locus-tag	class	description
CJO35_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CJO35_RS00010	COG0592	DNA-directed DNA polymerase activity
CJO35_RS00015	COG2501	S4 domain
CJO35_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CJO35_RS00030	COG0187	DNA topoisomerase II activity
CJO35_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CJO35_RS00070	COG0516	GMP reductase activity
CJO35_RS00070	COG0517	IMP dehydrogenase activity
CJO35_RS00075	COG1686	Belongs to the peptidase S11 family
CJO35_RS00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CJO35_RS00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CJO35_RS00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CJO35_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
CJO35_RS00100	COG2610	gluconate transmembrane transporter activity
CJO35_RS00105	COG3835	regulator
CJO35_RS00120	COG1428	Deoxynucleoside kinase
CJO35_RS00125	COG1428	Deoxynucleoside kinase
CJO35_RS00130	COG3858	chitin binding
CJO35_RS00130	COG1388	LysM domain
CJO35_RS00135	COG1335	isochorismatase
CJO35_RS00140	COG0590	tRNA wobble adenosine to inosine editing
CJO35_RS00150	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CJO35_RS00155	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CJO35_RS00160	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CJO35_RS00205	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
CJO35_RS00210	COG3853	Toxic anion resistance protein (TelA)
CJO35_RS00215	COG1982	Orn Lys Arg decarboxylase major
CJO35_RS00220	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CJO35_RS00225	COG3870	Protein conserved in bacteria
CJO35_RS00230	COG1728	Protein conserved in bacteria
CJO35_RS00235	COG0470	DNA polymerase III
CJO35_RS00240	COG1774	PSP1 C-terminal conserved region
CJO35_RS00245	COG4467	Involved in initiation control of chromosome replication
CJO35_RS00250	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CJO35_RS00255	COG2827	Endonuclease containing a URI domain
CJO35_RS00260	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CJO35_RS00265	COG2002	toxin-antitoxin pair type II binding
CJO35_RS00270	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CJO35_RS00270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CJO35_RS00275	COG0084	hydrolase, TatD family'
CJO35_RS00280	COG3583	domain protein
CJO35_RS00280	COG3584	3D domain protein
CJO35_RS00285	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CJO35_RS00290	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CJO35_RS00300	COG4466	Protein conserved in bacteria
CJO35_RS00310	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CJO35_RS00315	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CJO35_RS00320	COG0251	oxidation-reduction process
CJO35_RS00325	COG2088	sporulation resulting in formation of a cellular spore
CJO35_RS00330	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CJO35_RS00335	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CJO35_RS00340	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CJO35_RS00345	COG0193	aminoacyl-tRNA hydrolase activity
CJO35_RS00355	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CJO35_RS00360	COG2002	toxin-antitoxin pair type II binding
CJO35_RS00365	COG2244	polysaccharide biosynthetic process
CJO35_RS00370	COG3956	TIGRFAM MazG family protein
CJO35_RS00375	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CJO35_RS00390	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CJO35_RS00395	COG1098	S1 RNA binding domain
CJO35_RS00410	COG2208	phosphoserine phosphatase activity
CJO35_RS00415	COG2304	oxidoreductase activity
CJO35_RS00420	COG0515	serine threonine protein kinase
CJO35_RS00425	COG0037	tRNA processing
CJO35_RS00430	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CJO35_RS00435	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CJO35_RS00440	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CJO35_RS00445	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CJO35_RS00450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CJO35_RS00455	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CJO35_RS00465	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CJO35_RS00470	COG0512	Glutamine amidotransferase of anthranilate synthase
CJO35_RS00475	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CJO35_RS00480	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CJO35_RS00485	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CJO35_RS00490	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CJO35_RS00495	COG1396	sequence-specific DNA binding
CJO35_RS00500	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CJO35_RS00505	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CJO35_RS00585	COG4463	regulation of RNA biosynthetic process
CJO35_RS00590	COG3880	PFAM UvrB UvrC protein
CJO35_RS00595	COG3869	Catalyzes the specific phosphorylation of arginine residues in
CJO35_RS00600	COG0542	response to heat
CJO35_RS00605	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CJO35_RS00610	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CJO35_RS00615	COG4956	integral membrane protein (PIN domain superfamily)
CJO35_RS00620	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CJO35_RS00625	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CJO35_RS00630	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CJO35_RS00635	COG1045	serine acetyltransferase
CJO35_RS00640	COG0215	cysteine-tRNA ligase activity
CJO35_RS00645	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CJO35_RS00650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CJO35_RS00655	COG3688	RNA-binding protein containing a PIN domain
CJO35_RS00665	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CJO35_RS00675	COG0250	Participates in transcription elongation, termination and antitermination
CJO35_RS00680	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CJO35_RS00685	COG0081	regulation of translation
CJO35_RS00690	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CJO35_RS00695	COG0222	ribosome binding
CJO35_RS00700	COG2813	Specifically methylates the guanine in position
CJO35_RS00705	COG0085	RNA polymerase activity
CJO35_RS00710	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CJO35_RS00715	COG1358	cellular component organization or biogenesis
CJO35_RS00720	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CJO35_RS00725	COG0049	tRNA binding
CJO35_RS00730	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CJO35_RS00735	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CJO35_RS00745	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CJO35_RS00750	COG0088	Forms part of the polypeptide exit tunnel
CJO35_RS00755	COG0089	rRNA binding
CJO35_RS00760	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CJO35_RS00765	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CJO35_RS00770	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CJO35_RS00775	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CJO35_RS00780	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CJO35_RS00785	COG0255	Belongs to the universal ribosomal protein uL29 family
CJO35_RS00790	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CJO35_RS00795	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CJO35_RS00800	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CJO35_RS00805	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CJO35_RS00810	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CJO35_RS00815	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CJO35_RS00820	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CJO35_RS00825	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CJO35_RS00830	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CJO35_RS00835	COG1841	ribosomal large subunit assembly
CJO35_RS00840	COG0200	Binds to the 23S rRNA
CJO35_RS00845	COG0201	protein transport
CJO35_RS00850	COG0563	adenylate kinase activity
CJO35_RS00855	COG0024	Methionine aminopeptidase
CJO35_RS00860	COG2163	COG2163 Ribosomal protein L14E L6E L27E
CJO35_RS00865	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CJO35_RS00870	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CJO35_RS00875	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CJO35_RS00880	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CJO35_RS00885	COG0202	RNA polymerase activity
CJO35_RS00890	COG0203	ribosomal protein L17
CJO35_RS00895	COG1122	ATPase activity
CJO35_RS00900	COG1122	ATPase activity
CJO35_RS00905	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CJO35_RS00910	COG0101	tRNA pseudouridine synthase activity
CJO35_RS00915	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CJO35_RS00920	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CJO35_RS00925	COG2318	DinB family
CJO35_RS00935	COG0860	N-Acetylmuramoyl-L-alanine amidase
CJO35_RS00940	COG0489	protein tyrosine kinase activity
CJO35_RS00950	COG2194	sulfuric ester hydrolase activity
CJO35_RS00955	COG0726	polysaccharide deacetylase
CJO35_RS00985	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CJO35_RS00995	COG0385	Bile acid
CJO35_RS01010	COG3876	Protein conserved in bacteria
CJO35_RS01015	COG1472	Belongs to the glycosyl hydrolase 3 family
CJO35_RS01020	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CJO35_RS01025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CJO35_RS01025	COG1263	PTS System
CJO35_RS01030	COG1737	Transcriptional regulator
CJO35_RS01035	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CJO35_RS01040	COG1683	Conserved Protein
CJO35_RS01075	COG1595	DNA-templated transcription, initiation
CJO35_RS01080	COG5662	AntiSigma factor
CJO35_RS01085	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CJO35_RS01090	COG4856	YbbR-like protein
CJO35_RS01095	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CJO35_RS01100	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CJO35_RS01120	COG1725	Transcriptional regulator
CJO35_RS01125	COG0640	Transcriptional regulator
CJO35_RS01130	COG2814	Major facilitator Superfamily
CJO35_RS01140	COG1132	(ABC) transporter
CJO35_RS01145	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CJO35_RS01170	COG1011	Hydrolase
CJO35_RS01175	COG1113	amino acid transport
CJO35_RS01180	COG2851	Citrate transporter
CJO35_RS01185	COG3181	Tripartite tricarboxylate transporter family receptor
CJO35_RS01190	COG4565	transcriptional regulatory protein
CJO35_RS01195	COG3290	protein histidine kinase activity
CJO35_RS01210	COG2211	Major facilitator Superfamily
CJO35_RS01230	COG1331	Highly conserved protein containing a thioredoxin domain
CJO35_RS01235	COG3677	Transposase
CJO35_RS01270	COG1846	Transcriptional regulator
CJO35_RS01275	COG1331	Highly conserved protein containing a thioredoxin domain
CJO35_RS01285	COG0477	Major facilitator Superfamily
CJO35_RS01305	COG1283	sodium-dependent phosphate transmembrane transporter activity
CJO35_RS01310	COG4682	membrane
CJO35_RS01335	COG0697	spore germination
CJO35_RS01340	COG2207	Transcriptional regulator
CJO35_RS01340	COG1917	Cupin 2, conserved barrel domain protein
CJO35_RS01360	COG0371	Dehydrogenase
CJO35_RS01365	COG0840	transmembrane signaling receptor activity
CJO35_RS01370	COG4213	ABC transporter substrate-binding protein
CJO35_RS01385	COG4257	antibiotic catabolic process
CJO35_RS01395	COG0833	amino acid
CJO35_RS01400	COG2040	homocysteine
CJO35_RS01410	COG1263	PTS System
CJO35_RS01410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CJO35_RS01410	COG2190	(PTS) system
CJO35_RS01415	COG0789	Transcriptional regulator
CJO35_RS01420	COG2323	membrane
CJO35_RS01425	COG4451	ribulose bisphosphate carboxylase, small
CJO35_RS01425	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CJO35_RS01435	COG2205	protein histidine kinase activity
CJO35_RS01440	COG1115	amino acid carrier protein
CJO35_RS01445	COG2066	Belongs to the glutaminase family
CJO35_RS01450	COG4191	Histidine kinase
CJO35_RS01455	COG0784	Response regulator, receiver
CJO35_RS01480	COG3540	Alkaline phosphatase
CJO35_RS01485	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CJO35_RS01490	COG0805	protein transport
CJO35_RS01495	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CJO35_RS01500	COG1012	belongs to the aldehyde dehydrogenase family
CJO35_RS01505	COG2271	Major facilitator Superfamily
CJO35_RS01510	COG4948	Mandelate Racemase Muconate Lactonizing
CJO35_RS01515	COG2186	Transcriptional regulator
CJO35_RS01520	COG2721	sulfolactate sulfo-lyase activity
CJO35_RS01525	COG0745	RESPONSE REGULATOR receiver
CJO35_RS01530	COG2205	protein histidine kinase activity
CJO35_RS01535	COG1131	(ABC) transporter
CJO35_RS01560	COG3173	Aminoglycoside phosphotransferase
CJO35_RS01565	COG1846	Transcriptional regulator
CJO35_RS01570	COG0318	PFAM AMP-dependent synthetase and ligase
CJO35_RS01590	COG0789	Transcriptional regulator
CJO35_RS01620	COG1714	RDD family
CJO35_RS01625	COG3012	SEC-C Motif Domain Protein
CJO35_RS01625	COG1405	negative regulation of cell septum assembly
CJO35_RS01630	COG1131	(ABC) transporter
CJO35_RS01655	COG0583	DNA-binding transcription factor activity
CJO35_RS01660	COG1942	4-Oxalocrotonate Tautomerase
CJO35_RS01680	COG1288	antiporter activity
CJO35_RS01690	COG0456	acetyltransferase
CJO35_RS01700	COG1164	Oligoendopeptidase f
CJO35_RS01705	COG2261	transglycosylase associated protein
CJO35_RS01715	COG0247	lactate metabolic process
CJO35_RS01720	COG0277	FAD linked oxidase domain protein
CJO35_RS01725	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CJO35_RS01730	COG1447	Phosphotransferase system cellobiose-specific component IIA
CJO35_RS01735	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CJO35_RS01740	COG1486	melibiose metabolic process
CJO35_RS01745	COG2188	Transcriptional regulator
CJO35_RS01750	COG3394	polysaccharide catabolic process
CJO35_RS01765	COG3591	Belongs to the peptidase S1B family
CJO35_RS01770	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_RS01780	COG1595	DNA-templated transcription, initiation
CJO35_RS01790	COG3773	Cell wall hydrolase
CJO35_RS01795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CJO35_RS01800	COG0791	NLP P60 protein
CJO35_RS01800	COG3883	PFAM NLP P60 protein
CJO35_RS01810	COG1131	(ABC) transporter
CJO35_RS01815	COG1309	transcriptional regulator
CJO35_RS01835	COG2310	stress, protein
CJO35_RS01840	COG2310	stress, protein
CJO35_RS01845	COG2310	stress, protein
CJO35_RS01850	COG0861	Integral membrane protein TerC family
CJO35_RS01870	COG3853	Toxic anion resistance protein (TelA)
CJO35_RS01875	COG0785	Cytochrome C biogenesis protein
CJO35_RS01885	COG0789	Transcriptional regulator
CJO35_RS01890	COG2223	nitrite transmembrane transporter activity
CJO35_RS01895	COG0039	L-malate dehydrogenase activity
CJO35_RS01900	COG1620	l-lactate permease
CJO35_RS01905	COG1280	lysine exporter protein (LysE YggA)
CJO35_RS01910	COG1113	amino acid transport
CJO35_RS01915	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CJO35_RS01920	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CJO35_RS01925	COG3541	Predicted nucleotidyltransferase
CJO35_RS01930	COG0506	proline dehydrogenase activity
CJO35_RS01935	COG1012	belongs to the aldehyde dehydrogenase family
CJO35_RS01940	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CJO35_RS01945	COG2508	Transcriptional regulator
CJO35_RS01950	COG3689	TIGRFAM TIGR03943 family protein
CJO35_RS01955	COG0701	Predicted permease
CJO35_RS01960	COG3458	cephalosporin-C deacetylase activity
CJO35_RS01980	COG0765	amino acid transport
CJO35_RS01985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CJO35_RS01990	COG2249	NAD(P)H dehydrogenase (quinone) activity
CJO35_RS02000	COG2723	6-phospho-beta-galactosidase activity
CJO35_RS02010	COG3209	COG3209 Rhs family protein
CJO35_RS02015	COG3266	domain, Protein
CJO35_RS02015	COG0515	serine threonine protein kinase
CJO35_RS02025	COG5444	nuclease activity
CJO35_RS02050	COG1176	ABC-type spermidine putrescine transport system, permease component I
CJO35_RS02055	COG1177	transmembrane transport
CJO35_RS02060	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CJO35_RS02065	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CJO35_RS02070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CJO35_RS02075	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CJO35_RS02080	COG0697	spore germination
CJO35_RS02085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CJO35_RS02095	COG2819	hydrolase of the alpha beta superfamily
CJO35_RS02105	COG2364	Membrane
CJO35_RS02115	COG1131	(ABC) transporter
CJO35_RS02140	COG1126	abc transporter atp-binding protein
CJO35_RS02145	COG0765	amino acid transport
CJO35_RS02150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CJO35_RS02155	COG3829	transcription factor binding
CJO35_RS02160	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CJO35_RS02165	COG0833	amino acid
CJO35_RS02170	COG0010	Belongs to the arginase family
CJO35_RS02175	COG0583	DNA-binding transcription factor activity
CJO35_RS02180	COG0163	prenyltransferase activity
CJO35_RS02185	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CJO35_RS02235	COG5444	nuclease activity
CJO35_RS02255	COG2972	Histidine kinase
CJO35_RS02260	COG2207	Transcriptional regulator
CJO35_RS02260	COG4753	response regulator
CJO35_RS02265	COG4213	ABC transporter substrate-binding protein
CJO35_RS02275	COG4214	carbohydrate transport
CJO35_RS02280	COG2271	Major facilitator Superfamily
CJO35_RS02285	COG0456	acetyltransferase
CJO35_RS02285	COG1846	Transcriptional regulator
CJO35_RS02290	COG1874	Beta-galactosidase
CJO35_RS02300	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
CJO35_RS02305	COG3104	oligopeptide transport
CJO35_RS02310	COG5434	Belongs to the glycosyl hydrolase 28 family
CJO35_RS02320	COG0697	spore germination
CJO35_RS02330	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CJO35_RS02340	COG1136	(ABC) transporter
CJO35_RS02345	COG0577	efflux transmembrane transporter activity
CJO35_RS02350	COG0745	RESPONSE REGULATOR receiver
CJO35_RS02355	COG3850	Histidine kinase
CJO35_RS02355	COG5002	protein histidine kinase activity
CJO35_RS02360	COG0840	transmembrane signaling receptor activity
CJO35_RS02365	COG0527	aspartate kinase activity
CJO35_RS02370	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CJO35_RS02375	COG4605	iron ion homeostasis
CJO35_RS02380	COG4604	ABC transporter, ATP-binding protein
CJO35_RS02385	COG4607	ABC-type enterochelin transport system periplasmic component
CJO35_RS02390	COG2814	Major facilitator Superfamily
CJO35_RS02395	COG1309	transcriptional regulator
CJO35_RS02405	COG0778	Nitroreductase
CJO35_RS02410	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CJO35_RS02415	COG0640	Transcriptional regulator
CJO35_RS02420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CJO35_RS02425	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CJO35_RS02430	COG0531	amino acid
CJO35_RS02435	COG1012	belongs to the aldehyde dehydrogenase family
CJO35_RS02440	COG0697	spore germination
CJO35_RS02450	COG4549	nuclear export factor GLE1
CJO35_RS02455	COG2372	response to copper ion
CJO35_RS02455	COG1276	copper resistance
CJO35_RS02460	COG1349	DNA-binding transcription factor activity
CJO35_RS02465	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CJO35_RS02470	COG0243	molybdopterin cofactor binding
CJO35_RS02475	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CJO35_RS02480	COG2146	nitrite reductase [NAD(P)H] activity
CJO35_RS02485	COG1587	Uroporphyrinogen-III synthase
CJO35_RS02485	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CJO35_RS02490	COG1802	Transcriptional regulator
CJO35_RS02495	COG0471	metal ion transport
CJO35_RS02500	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CJO35_RS02505	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CJO35_RS02520	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CJO35_RS02535	COG3959	Transketolase, thiamine diphosphate binding domain
CJO35_RS02540	COG3958	Transketolase
CJO35_RS02545	COG0561	phosphatase activity
CJO35_RS02550	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CJO35_RS02555	COG1914	H( )-stimulated, divalent metal cation uptake system
CJO35_RS02560	COG4336	lyase activity
CJO35_RS02565	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CJO35_RS02570	COG1984	allophanate hydrolase subunit 2
CJO35_RS02575	COG1414	Transcriptional regulator
CJO35_RS02580	COG2755	lipolytic protein G-D-S-L family
CJO35_RS02585	COG2213	PTS system mannitol-specific
CJO35_RS02590	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CJO35_RS02595	COG0246	Mannitol dehydrogenase
CJO35_RS02600	COG3711	transcriptional antiterminator
CJO35_RS02605	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_RS02610	COG1917	Cupin 2, conserved barrel domain protein
CJO35_RS02620	COG3871	stress protein (general stress protein 26)
CJO35_RS02635	COG2814	Major facilitator Superfamily
CJO35_RS02645	COG1522	sequence-specific DNA binding
CJO35_RS02650	COG0551	DNA topoisomerase type I activity
CJO35_RS02650	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CJO35_RS02655	COG0531	amino acid
CJO35_RS02660	COG0028	Belongs to the TPP enzyme family
CJO35_RS02675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CJO35_RS02680	COG1914	H( )-stimulated, divalent metal cation uptake system
CJO35_RS02685	COG2261	transglycosylase associated protein
CJO35_RS02690	COG1027	Aspartate ammonia-lyase
CJO35_RS02695	COG1819	glycosyl
CJO35_RS02700	COG4876	unkown
CJO35_RS02705	COG2217	Heavy metal translocating P-type atpase
CJO35_RS02715	COG0662	Cupin 2, conserved barrel domain protein
CJO35_RS02720	COG3729	General stress protein
CJO35_RS02725	COG0628	permease
CJO35_RS02730	COG1301	dicarboxylic acid transport
CJO35_RS02735	COG1131	(ABC) transporter
CJO35_RS02740	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CJO35_RS02750	COG1960	acyl-CoA dehydrogenase activity
CJO35_RS02765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CJO35_RS02770	COG1181	Belongs to the D-alanine--D-alanine ligase family
CJO35_RS02775	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CJO35_RS02785	COG0513	Belongs to the DEAD box helicase family
CJO35_RS02790	COG3402	PFAM membrane-flanked domain
CJO35_RS02795	COG3428	Bacterial PH domain
CJO35_RS02800	COG0705	Rhomboid family
CJO35_RS02805	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CJO35_RS02810	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CJO35_RS02815	COG0864	Transcriptional regulator
CJO35_RS02820	COG2337	Toxic component of a toxin-antitoxin (TA) module
CJO35_RS02825	COG1366	Belongs to the anti-sigma-factor antagonist family
CJO35_RS02830	COG1366	Belongs to the anti-sigma-factor antagonist family
CJO35_RS02835	COG2172	sigma factor antagonist activity
CJO35_RS02840	COG2208	phosphoserine phosphatase activity
CJO35_RS02850	COG2172	sigma factor antagonist activity
CJO35_RS02855	COG1191	sigma factor activity
CJO35_RS02860	COG2208	phosphoserine phosphatase activity
CJO35_RS02865	COG2183	response to ionizing radiation
CJO35_RS02870	COG1309	transcriptional regulator
CJO35_RS02875	COG2409	Drug exporters of the RND superfamily
CJO35_RS02875	COG1033	growth of symbiont in host cell
CJO35_RS02885	COG3091	SprT-like family
CJO35_RS02935	COG1476	TRANSCRIPTIONal
CJO35_RS02940	COG3239	Fatty acid desaturase
CJO35_RS02945	COG1278	Cold shock
CJO35_RS02950	COG1063	alcohol dehydrogenase
CJO35_RS02960	COG2364	Membrane
CJO35_RS02965	COG1846	Transcriptional regulator
CJO35_RS02970	COG0456	acetyltransferase
CJO35_RS02975	COG2808	Putative FMN-binding domain
CJO35_RS02985	COG1733	regulation of RNA biosynthetic process
CJO35_RS02990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CJO35_RS03000	COG0583	DNA-binding transcription factor activity
CJO35_RS03015	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CJO35_RS03020	COG1113	amino acid transport
CJO35_RS03035	COG1595	DNA-templated transcription, initiation
CJO35_RS03045	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CJO35_RS03045	COG2755	lipolytic protein G-D-S-L family
CJO35_RS03050	COG2814	Major facilitator Superfamily
CJO35_RS03055	COG0745	RESPONSE REGULATOR receiver
CJO35_RS03055	COG2972	Histidine kinase
CJO35_RS03060	COG3279	Response regulator of the LytR AlgR family
CJO35_RS03070	COG3764	Sortase (surface protein transpeptidase)
CJO35_RS03075	COG2814	Major facilitator Superfamily
CJO35_RS03115	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CJO35_RS03120	COG0802	atpase or kinase
CJO35_RS03125	COG1214	PFAM Peptidase M22, glycoprotease
CJO35_RS03130	COG0456	acetyltransferase
CJO35_RS03135	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CJO35_RS03140	COG0488	(ABC) transporter
CJO35_RS03145	COG0315	cyclic pyranopterin monophosphate synthase activity
CJO35_RS03150	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CJO35_RS03155	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CJO35_RS03160	COG0805	protein transport
CJO35_RS03170	COG1266	CAAX protease self-immunity
CJO35_RS03175	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CJO35_RS03180	COG0459	protein refolding
CJO35_RS03215	COG2720	vancomycin resistance protein
CJO35_RS03230	COG2135	peptidase activity
CJO35_RS03240	COG1309	transcriptional regulator
CJO35_RS03245	COG0574	Belongs to the PEP-utilizing enzyme family
CJO35_RS03245	COG3848	Pyruvate phosphate dikinase
CJO35_RS03255	COG3189	MarR family transcriptional regulator
CJO35_RS03260	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CJO35_RS03265	COG2272	Belongs to the type-B carboxylesterase lipase family
CJO35_RS03270	COG2814	Major facilitator Superfamily
CJO35_RS03275	COG1842	Phage shock protein A
CJO35_RS03280	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CJO35_RS03285	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CJO35_RS03290	COG4260	virion core protein, lumpy skin disease virus
CJO35_RS03300	COG1378	Sugar-specific transcriptional regulator TrmB
CJO35_RS03305	COG1280	lysine exporter protein (LysE YggA)
CJO35_RS03310	COG3339	Conserved Protein
CJO35_RS03315	COG0772	Belongs to the SEDS family
CJO35_RS03320	COG0772	Belongs to the SEDS family
CJO35_RS03345	COG0726	polysaccharide deacetylase
CJO35_RS03355	COG1609	Transcriptional regulator
CJO35_RS03360	COG0366	Alpha amylase catalytic
CJO35_RS03365	COG2182	Extracellular solute-binding protein
CJO35_RS03370	COG1175	transmembrane transport
CJO35_RS03375	COG3833	ABC-type maltose transport systems, permease component
CJO35_RS03380	COG5521	maltodextrose utilization protein MalA
CJO35_RS03385	COG1554	hydrolase, family 65, central catalytic
CJO35_RS03390	COG0366	Alpha amylase catalytic
CJO35_RS03395	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CJO35_RS03400	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CJO35_RS03405	COG1846	Transcriptional regulator
CJO35_RS03420	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CJO35_RS03425	COG0823	Involved in the tonB-independent uptake of proteins
CJO35_RS03455	COG0702	epimerase
CJO35_RS03465	COG2132	Multicopper oxidase
CJO35_RS03480	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CJO35_RS03485	COG0714	Associated with various cellular activities
CJO35_RS03490	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
CJO35_RS03495	COG1305	Transglutaminase-like
CJO35_RS03500	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CJO35_RS03500	COG0519	Catalyzes the synthesis of GMP from XMP
CJO35_RS03510	COG2252	PERMEase
CJO35_RS03525	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
CJO35_RS03535	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CJO35_RS03540	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CJO35_RS03545	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CJO35_RS03550	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CJO35_RS03555	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CJO35_RS03560	COG0047	phosphoribosylformylglycinamidine synthase activity
CJO35_RS03565	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CJO35_RS03570	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CJO35_RS03575	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CJO35_RS03580	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CJO35_RS03585	COG0138	bifunctional purine biosynthesis protein purh
CJO35_RS03590	COG0151	Belongs to the GarS family
CJO35_RS03605	COG2124	cytochrome p450
CJO35_RS03625	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CJO35_RS03630	COG1470	cell adhesion involved in biofilm formation
CJO35_RS03635	COG4496	protein, YerC YecD
CJO35_RS03640	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
CJO35_RS03645	COG0210	DNA helicase
CJO35_RS03650	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CJO35_RS03655	COG4851	CamS sex pheromone cAM373 precursor
CJO35_RS03660	COG2188	Transcriptional regulator
CJO35_RS03680	COG1735	metal-dependent hydrolase with the TIM-barrel fold
CJO35_RS03685	COG0626	cystathionine gamma-synthase activity
CJO35_RS03690	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CJO35_RS03695	COG3457	Alanine racemase
CJO35_RS03700	COG0363	glucosamine-6-phosphate deaminase activity
CJO35_RS03705	COG1285	pathogenesis
CJO35_RS03710	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CJO35_RS03715	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CJO35_RS03720	COG0154	amidase activity
CJO35_RS03725	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CJO35_RS03745	COG1309	transcriptional regulator
CJO35_RS03750	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CJO35_RS03760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CJO35_RS03765	COG1957	nucleoside hydrolase
CJO35_RS03770	COG1597	lipid kinase activity
CJO35_RS03775	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CJO35_RS03795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CJO35_RS03795	COG2190	(PTS) system
CJO35_RS03795	COG1263	PTS System
CJO35_RS03800	COG2723	6-phospho-beta-galactosidase activity
CJO35_RS03805	COG3711	transcriptional antiterminator
CJO35_RS03810	COG0457	Tetratricopeptide repeat
CJO35_RS03830	COG0217	transcriptional regulatory protein
CJO35_RS03845	COG1012	belongs to the aldehyde dehydrogenase family
CJO35_RS03850	COG0840	transmembrane signaling receptor activity
CJO35_RS03855	COG0471	metal ion transport
CJO35_RS03860	COG0488	(ABC) transporter
CJO35_RS03865	COG1469	GTP cyclohydrolase I activity
CJO35_RS03880	COG0523	cobalamin synthesis protein
CJO35_RS03885	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
CJO35_RS03890	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CJO35_RS03895	COG0156	8-amino-7-oxononanoate synthase activity
CJO35_RS03900	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CJO35_RS03905	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CJO35_RS03910	COG2124	cytochrome p450
CJO35_RS03920	COG0789	Transcriptional regulator
CJO35_RS03925	COG2814	Major facilitator Superfamily
CJO35_RS03930	COG0488	(ABC) transporter
CJO35_RS03935	COG0513	Belongs to the DEAD box helicase family
CJO35_RS03940	COG2130	NADP-dependent
CJO35_RS03955	COG0471	metal ion transport
CJO35_RS03975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CJO35_RS03985	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
CJO35_RS03990	COG5658	integral membrane protein
CJO35_RS03995	COG0640	Transcriptional regulator
CJO35_RS04000	COG1254	Belongs to the acylphosphatase family
CJO35_RS04005	COG2258	MOSC domain
CJO35_RS04020	COG0024	Methionine aminopeptidase
CJO35_RS04025	COG1368	sulfuric ester hydrolase activity
CJO35_RS04035	COG1115	amino acid carrier protein
CJO35_RS04040	COG1263	PTS System
CJO35_RS04040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CJO35_RS04045	COG0366	Alpha amylase catalytic
CJO35_RS04050	COG2188	Transcriptional regulator
CJO35_RS04075	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CJO35_RS04080	COG1045	serine acetyltransferase
CJO35_RS04085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CJO35_RS04095	COG1215	transferase activity, transferring glycosyl groups
CJO35_RS04100	COG0463	Glycosyl transferase, family 2
CJO35_RS04100	COG0457	Tetratricopeptide repeat
CJO35_RS04110	COG0673	inositol 2-dehydrogenase activity
CJO35_RS04120	COG0657	acetylesterase activity
CJO35_RS04125	COG1733	regulation of RNA biosynthetic process
CJO35_RS04130	COG0778	Nitroreductase
CJO35_RS04135	COG0737	Belongs to the 5'-nucleotidase family
CJO35_RS04140	COG0693	protein deglycase activity
CJO35_RS04145	COG4840	Belongs to the UPF0435 family
CJO35_RS04150	COG1115	amino acid carrier protein
CJO35_RS04155	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CJO35_RS04160	COG4980	gas vesicle protein
CJO35_RS04165	COG1295	ribonuclease BN
CJO35_RS04170	COG0477	Major facilitator Superfamily
CJO35_RS04180	COG0387	Pfam Sodium calcium exchanger
CJO35_RS04190	COG0535	radical SAM domain protein
CJO35_RS04200	COG0726	polysaccharide deacetylase
CJO35_RS04205	COG0371	Dehydrogenase
CJO35_RS04215	COG0598	Magnesium transport protein CorA
CJO35_RS04220	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CJO35_RS04225	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CJO35_RS04230	COG4637	Psort location Cytoplasmic, score
CJO35_RS04255	COG1819	glycosyl
CJO35_RS04265	COG0477	Major facilitator Superfamily
CJO35_RS04270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CJO35_RS04270	COG1263	PTS System
CJO35_RS04275	COG3711	transcriptional antiterminator
CJO35_RS04280	COG0288	reversible hydration of carbon dioxide
CJO35_RS04285	COG3002	Belongs to the UPF0753 family
CJO35_RS04290	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CJO35_RS04295	COG5609	conserved protein (DUF2294)
CJO35_RS04305	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CJO35_RS04310	COG0022	dehydrogenase e1 component
CJO35_RS04315	COG0508	dehydrogenase complex catalyzes the overall conversion of
CJO35_RS04320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CJO35_RS04325	COG3284	Transcriptional regulator
CJO35_RS04330	COG1742	UPF0060 membrane protein
CJO35_RS04335	COG1486	melibiose metabolic process
CJO35_RS04340	COG1737	Transcriptional regulator
CJO35_RS04345	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CJO35_RS04345	COG1263	PTS System
CJO35_RS04360	COG1733	regulation of RNA biosynthetic process
CJO35_RS04365	COG2259	Doxx family
CJO35_RS04370	COG2514	catechol 2,3-dioxygenase activity
CJO35_RS04380	COG3507	Belongs to the glycosyl hydrolase 43 family
CJO35_RS04385	COG1917	Cupin 2, conserved barrel domain protein
CJO35_RS04385	COG2207	Transcriptional regulator
CJO35_RS04390	COG1653	transport
CJO35_RS04400	COG1051	belongs to the nudix hydrolase family
CJO35_RS04415	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CJO35_RS04415	COG0392	lysyltransferase activity
CJO35_RS04420	COG0384	phenazine biosynthesis protein PhzF
CJO35_RS04425	COG0778	Nitroreductase
CJO35_RS04445	COG1090	epimerase
CJO35_RS04450	COG2137	regulation of response to DNA damage stimulus
CJO35_RS04480	COG0463	Glycosyl transferase, family 2
CJO35_RS04490	COG4485	Bacterial membrane protein, YfhO
CJO35_RS04495	COG1988	membrane-bound metal-dependent
CJO35_RS04500	COG1194	a g-specific adenine glycosylase
CJO35_RS04510	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_RS04525	COG3557	Belongs to the UPF0374 family
CJO35_RS04530	COG1132	(ABC) transporter
CJO35_RS04535	COG0444	Belongs to the ABC transporter superfamily
CJO35_RS04540	COG4608	Belongs to the ABC transporter superfamily
CJO35_RS04545	COG0747	negative chemotaxis
CJO35_RS04550	COG0601	transmembrane transport
CJO35_RS04555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CJO35_RS04560	COG4129	membrane
CJO35_RS04565	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CJO35_RS04570	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CJO35_RS04575	COG0735	belongs to the Fur family
CJO35_RS04685	COG0457	Tetratricopeptide repeat
CJO35_RS04730	COG5444	nuclease activity
CJO35_RS04735	COG0457	Tetratricopeptide repeat
CJO35_RS04740	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CJO35_RS04750	COG0710	3-dehydroquinate dehydratase activity
CJO35_RS04755	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CJO35_RS04760	COG1116	anion transmembrane transporter activity
CJO35_RS04765	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CJO35_RS04770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CJO35_RS04775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CJO35_RS04785	COG1476	TRANSCRIPTIONal
CJO35_RS04795	COG1131	(ABC) transporter
CJO35_RS04815	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CJO35_RS04825	COG3382	B3 4 domain protein
CJO35_RS04830	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CJO35_RS04840	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CJO35_RS04845	COG0789	Transcriptional regulator
CJO35_RS04850	COG1664	Polymer-forming cytoskeletal
CJO35_RS04860	COG2766	serine protein kinase
CJO35_RS04865	COG2718	Belongs to the UPF0229 family
CJO35_RS04870	COG1566	PFAM secretion protein HlyD family protein
CJO35_RS04875	COG2814	Major facilitator Superfamily
CJO35_RS04880	COG0655	NAD(P)H dehydrogenase (quinone) activity
CJO35_RS04900	COG1131	(ABC) transporter
CJO35_RS04905	COG1131	(ABC) transporter
CJO35_RS04910	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CJO35_RS04915	COG1278	Cold shock
CJO35_RS04920	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CJO35_RS04925	COG2011	ABC-type metal ion transport system permease component
CJO35_RS04930	COG1464	Belongs to the NlpA lipoprotein family
CJO35_RS04935	COG1823	symporter activity
CJO35_RS04960	COG5577	PFAM Coat F domain
CJO35_RS04965	COG5002	protein histidine kinase activity
CJO35_RS04970	COG0737	Belongs to the 5'-nucleotidase family
CJO35_RS04970	COG4085	toxin activity
CJO35_RS04970	COG1525	nuclease
CJO35_RS04975	COG3764	Sortase (surface protein transpeptidase)
CJO35_RS04980	COG0564	pseudouridine synthase activity
CJO35_RS04990	COG0517	IMP dehydrogenase activity
CJO35_RS04995	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CJO35_RS05000	COG3153	acetyltransferase
CJO35_RS05000	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CJO35_RS05005	COG0488	(ABC) transporter
CJO35_RS05015	COG2116	formate transmembrane transporter activity
CJO35_RS05020	COG0679	Auxin Efflux Carrier
CJO35_RS05025	COG0604	alcohol dehydrogenase
CJO35_RS05030	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CJO35_RS05035	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CJO35_RS05040	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CJO35_RS05045	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CJO35_RS05050	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CJO35_RS05065	COG4585	Histidine kinase
CJO35_RS05065	COG2203	Gaf domain
CJO35_RS05070	COG2197	response regulator
CJO35_RS05075	COG0431	NADPH-dependent FMN reductase
CJO35_RS05090	COG1959	2 iron, 2 sulfur cluster binding
CJO35_RS05095	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CJO35_RS05095	COG1017	nitric oxide dioxygenase activity
CJO35_RS05100	COG2719	SpoVR family
CJO35_RS05105	COG1388	LysM domain
CJO35_RS05105	COG0791	NLP P60 protein
CJO35_RS05110	COG0583	DNA-binding transcription factor activity
CJO35_RS05115	COG0372	Belongs to the citrate synthase family
CJO35_RS05120	COG2133	pyrroloquinoline quinone binding
CJO35_RS05125	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_RS05130	COG0733	neurotransmitter:sodium symporter activity
CJO35_RS05140	COG2207	Transcriptional regulator
CJO35_RS05140	COG3708	Transcriptional regulator
CJO35_RS05145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CJO35_RS05165	COG1595	DNA-templated transcription, initiation
CJO35_RS05170	COG0662	Cupin 2, conserved barrel domain protein
CJO35_RS05180	COG0204	Acyl-transferase
CJO35_RS05185	COG3152	Membrane
CJO35_RS05195	COG1309	transcriptional regulator
CJO35_RS05200	COG1253	flavin adenine dinucleotide binding
CJO35_RS05205	COG0789	Transcriptional regulator
CJO35_RS05210	COG1253	flavin adenine dinucleotide binding
CJO35_RS05230	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CJO35_RS05235	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CJO35_RS05240	COG0584	glycerophosphoryl diester phosphodiesterase
CJO35_RS05250	COG0668	transmembrane transport
CJO35_RS05255	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CJO35_RS05265	COG0726	polysaccharide deacetylase
CJO35_RS05275	COG1757	Na H antiporter
CJO35_RS05280	COG2017	converts alpha-aldose to the beta-anomer
CJO35_RS05305	COG0589	response to stress
CJO35_RS05310	COG1132	(ABC) transporter
CJO35_RS05315	COG1132	(ABC) transporter
CJO35_RS05320	COG0702	epimerase
CJO35_RS05335	COG3842	ATPase activity
CJO35_RS05340	COG2508	Transcriptional regulator
CJO35_RS05350	COG0189	ligase activity
CJO35_RS05355	COG0189	ligase activity
CJO35_RS05360	COG4399	Belongs to the UPF0754 family
CJO35_RS05365	COG3679	Belongs to the UPF0342 family
CJO35_RS05375	COG0561	phosphatase activity
CJO35_RS05380	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CJO35_RS05385	COG0475	glutathione-regulated potassium exporter activity
CJO35_RS05390	COG0490	domain, Protein
CJO35_RS05400	COG1024	Enoyl-CoA hydratase
CJO35_RS05405	COG0457	Tetratricopeptide repeat
CJO35_RS05420	COG4152	abc transporter atp-binding protein
CJO35_RS05425	COG1668	transmembrane transport
CJO35_RS05430	COG0420	3'-5' exonuclease activity
CJO35_RS05435	COG4717	serine-type aminopeptidase activity
CJO35_RS05440	COG3481	metal-dependent phosphohydrolase, HD sub domain
CJO35_RS05450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CJO35_RS05480	COG1846	Transcriptional regulator
CJO35_RS05485	COG4980	gas vesicle protein
CJO35_RS05500	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CJO35_RS05505	COG0537	adenosine 5'-monophosphoramidase activity
CJO35_RS05515	COG1131	(ABC) transporter
CJO35_RS05520	COG4473	ABC transporter
CJO35_RS05530	COG1473	amidohydrolase
CJO35_RS05535	COG3069	C4-dicarboxylate transmembrane transporter activity
CJO35_RS05540	COG2329	Antibiotic biosynthesis monooxygenase
CJO35_RS05545	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CJO35_RS05550	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CJO35_RS05555	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CJO35_RS05560	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CJO35_RS05565	COG1309	transcriptional regulator
CJO35_RS05570	COG1511	domain protein
CJO35_RS05575	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CJO35_RS05580	COG1363	Peptidase, m42
CJO35_RS05590	COG1301	dicarboxylic acid transport
CJO35_RS05600	COG1234	tRNA 3'-trailer cleavage
CJO35_RS05605	COG0095	Lipoate-protein ligase
CJO35_RS05610	COG0318	PFAM AMP-dependent synthetase and ligase
CJO35_RS05620	COG1396	sequence-specific DNA binding
CJO35_RS05635	COG0501	Belongs to the peptidase M48B family
CJO35_RS05645	COG0697	spore germination
CJO35_RS05650	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CJO35_RS05655	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CJO35_RS05660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CJO35_RS05665	COG0406	alpha-ribazole phosphatase activity
CJO35_RS05670	COG0840	transmembrane signaling receptor activity
CJO35_RS05675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CJO35_RS05675	COG0723	plastoquinol--plastocyanin reductase activity
CJO35_RS05680	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_RS05690	COG4903	ComK protein
CJO35_RS05700	COG0398	Pfam SNARE associated Golgi protein
CJO35_RS05705	COG0681	Belongs to the peptidase S26 family
CJO35_RS05710	COG1404	Belongs to the peptidase S8 family
CJO35_RS05720	COG2508	Transcriptional regulator
CJO35_RS05730	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CJO35_RS05740	COG3257	ureidoglycine aminohydrolase activity
CJO35_RS05745	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CJO35_RS05750	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CJO35_RS05755	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CJO35_RS05760	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CJO35_RS05770	COG0549	Belongs to the carbamate kinase family
CJO35_RS05775	COG2814	Major facilitator Superfamily
CJO35_RS05785	COG0457	Tetratricopeptide repeat
CJO35_RS05805	COG1609	Transcriptional regulator
CJO35_RS05810	COG1653	transport
CJO35_RS05815	COG1175	transmembrane transport
CJO35_RS05820	COG0395	ABC-type sugar transport system, permease component
CJO35_RS05825	COG1486	melibiose metabolic process
CJO35_RS05830	COG3180	Ammonia monooxygenase
CJO35_RS05845	COG3546	catalase activity
CJO35_RS05850	COG0318	PFAM AMP-dependent synthetase and ligase
CJO35_RS05855	COG2814	Major facilitator Superfamily
CJO35_RS05855	COG0477	Major facilitator Superfamily
CJO35_RS05865	COG5002	protein histidine kinase activity
CJO35_RS05870	COG0745	RESPONSE REGULATOR receiver
CJO35_RS05875	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
CJO35_RS05880	COG0725	ABC transporter, periplasmic molybdate-binding protein
CJO35_RS05885	COG4149	molybdate abc transporter
CJO35_RS05890	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CJO35_RS05895	COG1074	ATP-dependent DNA helicase activity
CJO35_RS05900	COG0420	3'-5' exonuclease activity
CJO35_RS05905	COG0419	ATPase involved in DNA repair
CJO35_RS05950	COG5337	Spore coat protein CotH
CJO35_RS05960	COG0179	Fumarylacetoacetate (FAA) hydrolase
CJO35_RS05980	COG0367	asparagine synthase
CJO35_RS05985	COG0004	ammonium transporteR
CJO35_RS05990	COG0347	Belongs to the P(II) protein family
CJO35_RS05995	COG0534	Mate efflux family protein
CJO35_RS06000	COG1917	Cupin 2, conserved barrel domain protein
CJO35_RS06000	COG2207	Transcriptional regulator
CJO35_RS06010	COG1609	Transcriptional regulator
CJO35_RS06015	COG0673	inositol 2-dehydrogenase activity
CJO35_RS06035	COG1279	arginine transmembrane transporter activity
CJO35_RS06040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CJO35_RS06050	COG0076	glutamate decarboxylase activity
CJO35_RS06075	COG2153	protein acetylation
CJO35_RS06080	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_RS06085	COG2378	regulation of single-species biofilm formation
CJO35_RS06090	COG1410	methionine synthase
CJO35_RS06090	COG0646	methionine synthase
CJO35_RS06095	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CJO35_RS06095	COG0646	methionine synthase
CJO35_RS06100	COG1666	GTP binding
CJO35_RS06105	COG2996	Protein conserved in bacteria
CJO35_RS06120	COG1307	EDD domain protein, DegV family
CJO35_RS06125	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CJO35_RS06135	COG0516	GMP reductase activity
CJO35_RS06145	COG0561	phosphatase activity
CJO35_RS06150	COG1073	alpha beta
CJO35_RS06155	COG2151	metal-sulfur cluster biosynthetic enzyme
CJO35_RS06165	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CJO35_RS06170	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CJO35_RS06175	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CJO35_RS06180	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CJO35_RS06185	COG0505	Belongs to the CarA family
CJO35_RS06190	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CJO35_RS06195	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CJO35_RS06200	COG1968	undecaprenyl-diphosphatase activity
CJO35_RS06215	COG2267	carboxylic ester hydrolase activity
CJO35_RS06225	COG1744	ABC transporter substrate-binding protein PnrA-like
CJO35_RS06240	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CJO35_RS06245	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CJO35_RS06250	COG5504	Zn-dependent protease
CJO35_RS06255	COG0444	Belongs to the ABC transporter superfamily
CJO35_RS06260	COG4608	Belongs to the ABC transporter superfamily
CJO35_RS06270	COG0601	transmembrane transport
CJO35_RS06275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CJO35_RS06300	COG0180	Tryptophanyl-tRNA synthetase
CJO35_RS06310	COG4166	transmembrane transport
CJO35_RS06315	COG0601	transmembrane transport
CJO35_RS06320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CJO35_RS06325	COG0444	Belongs to the ABC transporter superfamily
CJO35_RS06330	COG4608	Belongs to the ABC transporter superfamily
CJO35_RS06335	COG0456	acetyltransferase
CJO35_RS06340	COG1393	Belongs to the ArsC family
CJO35_RS06345	COG0861	Integral membrane protein TerC family
CJO35_RS06350	COG4862	establishment of competence for transformation
CJO35_RS06370	COG4565	transcriptional regulatory protein
CJO35_RS06375	COG3290	protein histidine kinase activity
CJO35_RS06380	COG4469	Competence protein
CJO35_RS06385	COG1164	Oligoendopeptidase f
CJO35_RS06395	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CJO35_RS06400	COG2346	COG2346, Truncated hemoglobins
CJO35_RS06405	COG0741	lytic transglycosylase activity
CJO35_RS06410	COG4116	CYTH
CJO35_RS06420	COG2357	RelA SpoT domain protein
CJO35_RS06425	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CJO35_RS06430	COG0564	pseudouridine synthase activity
CJO35_RS06435	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CJO35_RS06445	COG0569	domain protein
CJO35_RS06445	COG0475	glutathione-regulated potassium exporter activity
CJO35_RS06450	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CJO35_RS06455	COG0352	thiamine-phosphate diphosphorylase activity
CJO35_RS06465	COG2104	thiamine diphosphate biosynthetic process
CJO35_RS06470	COG2022	thiamine diphosphate biosynthetic process
CJO35_RS06475	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CJO35_RS06480	COG0351	phosphomethylpyrimidine kinase
CJO35_RS06485	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CJO35_RS06540	COG0210	DNA helicase
CJO35_RS06550	COG0586	Pfam SNARE associated Golgi protein
CJO35_RS06555	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CJO35_RS06560	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CJO35_RS06565	COG2246	polysaccharide biosynthetic process
CJO35_RS06570	COG2153	protein acetylation
CJO35_RS06575	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CJO35_RS06580	COG2382	esterase
CJO35_RS06600	COG0626	cystathionine gamma-synthase activity
CJO35_RS06605	COG0626	cystathionine gamma-synthase activity
CJO35_RS06630	COG3507	Belongs to the glycosyl hydrolase 43 family
CJO35_RS06650	COG0110	maltose O-acetyltransferase activity
CJO35_RS06660	COG0583	DNA-binding transcription factor activity
CJO35_RS06665	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CJO35_RS06670	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CJO35_RS06675	COG0583	DNA-binding transcription factor activity
CJO35_RS06680	COG0697	spore germination
CJO35_RS06685	COG0346	lactoylglutathione lyase activity
CJO35_RS06695	COG3584	3D domain protein
CJO35_RS06695	COG1388	LysM domain
CJO35_RS06700	COG2814	Major facilitator Superfamily
CJO35_RS06705	COG1309	transcriptional regulator
CJO35_RS06730	COG4195	phage-related replication protein
CJO35_RS06735	COG2856	Zn peptidase
CJO35_RS06740	COG1396	sequence-specific DNA binding
CJO35_RS06755	COG1522	sequence-specific DNA binding
CJO35_RS06760	COG1484	DNA-dependent DNA replication
CJO35_RS06775	COG1595	DNA-templated transcription, initiation
CJO35_RS06780	COG3728	DNA packaging
CJO35_RS06780	COG5484	DNA packaging
CJO35_RS06785	COG1783	phage Terminase large subunit
CJO35_RS06790	COG5518	Phage portal protein
CJO35_RS06795	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CJO35_RS06800	COG4653	Phage capsid family
CJO35_RS06855	COG1652	LysM domain
CJO35_RS06860	COG4193	domain, Protein
CJO35_RS06870	COG3628	GPW Gp25 family protein
CJO35_RS06875	COG3299	homolog of phage Mu protein gp47
CJO35_RS06880	COG3778	Protein conserved in bacteria
CJO35_RS06915	COG1802	Transcriptional regulator
CJO35_RS06920	COG1063	alcohol dehydrogenase
CJO35_RS06925	COG1312	Catalyzes the dehydration of D-mannonate
CJO35_RS06930	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_RS06935	COG1063	alcohol dehydrogenase
CJO35_RS06940	COG2271	Major facilitator Superfamily
CJO35_RS06955	COG0306	phosphate transporter
CJO35_RS06960	COG1392	Phosphate transport regulator
CJO35_RS06965	COG0405	Gamma-glutamyltransferase
CJO35_RS06970	COG5578	integral membrane protein
CJO35_RS06975	COG2972	Histidine kinase
CJO35_RS06980	COG2207	Transcriptional regulator
CJO35_RS06980	COG4753	response regulator
CJO35_RS06985	COG1653	transport
CJO35_RS06990	COG1175	transmembrane transport
CJO35_RS06995	COG0395	ABC-type sugar transport system, permease component
CJO35_RS07000	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CJO35_RS07005	COG2207	Transcriptional regulator
CJO35_RS07010	COG2755	lipolytic protein G-D-S-L family
CJO35_RS07020	COG5578	integral membrane protein
CJO35_RS07025	COG3401	FG-GAP repeat protein
CJO35_RS07035	COG2755	lipolytic protein G-D-S-L family
CJO35_RS07040	COG3401	FG-GAP repeat protein
CJO35_RS07045	COG0667	Aldo Keto reductase
CJO35_RS07050	COG2755	lipolytic protein G-D-S-L family
CJO35_RS07055	COG1874	Beta-galactosidase
CJO35_RS07065	COG1653	transport
CJO35_RS07070	COG4209	transmembrane transport
CJO35_RS07075	COG0395	ABC-type sugar transport system, permease component
CJO35_RS07080	COG0531	amino acid
CJO35_RS07085	COG0346	lactoylglutathione lyase activity
CJO35_RS07095	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CJO35_RS07100	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CJO35_RS07105	COG2362	D-Aminopeptidase
CJO35_RS07110	COG0601	transmembrane transport
CJO35_RS07115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CJO35_RS07120	COG0444	Belongs to the ABC transporter superfamily
CJO35_RS07125	COG4166	transmembrane transport
CJO35_RS07130	COG1619	proteins homologs of microcin C7 resistance protein MccF
CJO35_RS07135	COG4948	Mandelate Racemase Muconate Lactonizing
CJO35_RS07140	COG0791	NLP P60 protein
CJO35_RS07145	COG4608	Belongs to the ABC transporter superfamily
CJO35_RS07150	COG1834	amidinotransferase
CJO35_RS07155	COG1607	acyl-coa hydrolase
CJO35_RS07190	COG2076	Multidrug Resistance protein
CJO35_RS07195	COG2076	Multidrug Resistance protein
CJO35_RS07200	COG0788	formyltetrahydrofolate deformylase activity
CJO35_RS07205	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CJO35_RS07210	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CJO35_RS07215	COG1764	response to oxidative stress
CJO35_RS07220	COG1846	Transcriptional regulator
CJO35_RS07225	COG1764	response to oxidative stress
CJO35_RS07235	COG0590	tRNA wobble adenosine to inosine editing
CJO35_RS07240	COG0406	alpha-ribazole phosphatase activity
CJO35_RS07255	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CJO35_RS07260	COG1404	Belongs to the peptidase S8 family
CJO35_RS07265	COG2239	Acts as a magnesium transporter
CJO35_RS07280	COG2856	Zn peptidase
CJO35_RS07290	COG3620	sequence-specific DNA binding
CJO35_RS07340	COG3935	DnaD domain protein
CJO35_RS07345	COG1484	DNA-dependent DNA replication
CJO35_RS07435	COG3677	Transposase
CJO35_RS07445	COG5484	DNA packaging
CJO35_RS07450	COG1783	phage Terminase large subunit
CJO35_RS07570	COG0662	Cupin 2, conserved barrel domain protein
CJO35_RS07575	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
CJO35_RS07580	COG2323	membrane
CJO35_RS07585	COG0789	Transcriptional regulator
CJO35_RS07600	COG1846	Transcriptional regulator
CJO35_RS07605	COG3285	dna ligase
CJO35_RS07605	COG1793	dna ligase
CJO35_RS07610	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CJO35_RS07615	COG3300	MHYT domain
CJO35_RS07615	COG5001	Diguanylate cyclase
CJO35_RS07620	COG0586	Pfam SNARE associated Golgi protein
CJO35_RS07625	COG0861	Integral membrane protein TerC family
CJO35_RS07630	COG1191	sigma factor activity
CJO35_RS07650	COG0501	Belongs to the peptidase M48B family
CJO35_RS07655	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CJO35_RS07660	COG0768	penicillin binding
CJO35_RS07675	COG3594	Acyltransferase
CJO35_RS07680	COG5002	protein histidine kinase activity
CJO35_RS07685	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CJO35_RS07695	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
CJO35_RS07700	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CJO35_RS07705	COG0436	Aminotransferase
CJO35_RS07710	COG1850	ribulose-bisphosphate carboxylase activity
CJO35_RS07715	COG0235	Class ii aldolase
CJO35_RS07715	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
CJO35_RS07720	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CJO35_RS07725	COG0346	lactoylglutathione lyase activity
CJO35_RS07730	COG3339	Conserved Protein
CJO35_RS07740	COG3852	Histidine kinase
CJO35_RS07745	COG1846	Transcriptional regulator
CJO35_RS07750	COG1360	Flagellar Motor Protein
CJO35_RS07755	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CJO35_RS07760	COG0542	response to heat
CJO35_RS07765	COG3949	Membrane
CJO35_RS07770	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CJO35_RS07775	COG0720	synthase
CJO35_RS07780	COG0602	queuosine metabolic process
CJO35_RS07785	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CJO35_RS07795	COG3739	integral membrane protein
CJO35_RS07800	COG3655	Transcriptional regulator
CJO35_RS07830	COG4873	Protein conserved in bacteria
CJO35_RS07840	COG3773	Cell wall hydrolase
CJO35_RS07845	COG2244	polysaccharide biosynthetic process
CJO35_RS07850	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CJO35_RS07855	COG2217	Heavy metal translocating P-type atpase
CJO35_RS07860	COG0006	proline dipeptidase activity
CJO35_RS07870	COG1609	Transcriptional regulator
CJO35_RS07875	COG3711	transcriptional antiterminator
CJO35_RS07880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CJO35_RS07880	COG1263	PTS System
CJO35_RS07880	COG2190	(PTS) system
CJO35_RS07885	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CJO35_RS07890	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CJO35_RS07900	COG1533	DNA photolyase activity
CJO35_RS07905	COG0456	acetyltransferase
CJO35_RS07910	COG0840	transmembrane signaling receptor activity
CJO35_RS07915	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_RS07920	COG2084	Dehydrogenase
CJO35_RS07925	COG2340	Cysteine-rich secretory protein family
CJO35_RS07930	COG0768	penicillin binding
CJO35_RS07935	COG4191	Histidine kinase
CJO35_RS07940	COG0436	Aminotransferase
CJO35_RS07945	COG1714	RDD family
CJO35_RS07955	COG0784	Response regulator, receiver
CJO35_RS07955	COG0835	chemotaxis
CJO35_RS07965	COG2814	Major facilitator Superfamily
CJO35_RS07970	COG1376	ErfK ybiS ycfS ynhG family protein
CJO35_RS07980	COG1408	metallophosphoesterase
CJO35_RS07985	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_RS07990	COG2200	EAL domain
CJO35_RS08000	COG4703	Protein of unknown function (DUF1797)
CJO35_RS08010	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
CJO35_RS08020	COG0517	IMP dehydrogenase activity
CJO35_RS08025	COG0583	DNA-binding transcription factor activity
CJO35_RS08030	COG0716	FMN binding
CJO35_RS08040	COG0716	FMN binding
CJO35_RS08045	COG2171	N-acyltransferase activity
CJO35_RS08050	COG1473	amidohydrolase
CJO35_RS08060	COG0450	alkyl hydroperoxide reductase
CJO35_RS08065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CJO35_RS08080	COG0746	molybdenum cofactor guanylyltransferase activity
CJO35_RS08085	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CJO35_RS08090	COG0303	'Molybdopterin
CJO35_RS08095	COG1763	Mo-molybdopterin cofactor biosynthetic process
CJO35_RS08100	COG0314	molybdopterin synthase activity
CJO35_RS08105	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CJO35_RS08115	COG1132	(ABC) transporter
CJO35_RS08120	COG1132	(ABC) transporter
CJO35_RS08130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CJO35_RS08135	COG1136	(ABC) transporter
CJO35_RS08140	COG0577	efflux transmembrane transporter activity
CJO35_RS08145	COG1349	DNA-binding transcription factor activity
CJO35_RS08150	COG1105	Belongs to the carbohydrate kinase PfkB family
CJO35_RS08155	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CJO35_RS08155	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CJO35_RS08155	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CJO35_RS08175	COG0488	(ABC) transporter
CJO35_RS08185	COG2309	aminopeptidase activity
CJO35_RS08195	COG1077	Cell shape determining protein MreB Mrl
CJO35_RS08200	COG2002	toxin-antitoxin pair type II binding
CJO35_RS08205	COG3852	Histidine kinase
CJO35_RS08210	COG0569	domain protein
CJO35_RS08215	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CJO35_RS08220	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CJO35_RS08225	COG5503	Protein of unknown function (DUF1447)
CJO35_RS08230	COG0561	phosphatase activity
CJO35_RS08240	COG0242	peptide deformylase activity
CJO35_RS08250	COG0497	DNA recombination
CJO35_RS08255	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CJO35_RS08260	COG0022	dehydrogenase e1 component
CJO35_RS08265	COG0508	dehydrogenase complex catalyzes the overall conversion of
CJO35_RS08270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CJO35_RS08275	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CJO35_RS08285	COG1982	Orn Lys Arg decarboxylase major
CJO35_RS08290	COG4476	Belongs to the UPF0223 family
CJO35_RS08295	COG4493	Belongs to the UPF0637 family
CJO35_RS08305	COG0483	inositol monophosphate 1-phosphatase activity
CJO35_RS08325	COG1595	DNA-templated transcription, initiation
CJO35_RS08340	COG1217	gtp-binding protein TYPA
CJO35_RS08350	COG1846	Transcriptional regulator
CJO35_RS08355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CJO35_RS08360	COG4896	Protein conserved in bacteria
CJO35_RS08370	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CJO35_RS08375	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CJO35_RS08380	COG2066	Belongs to the glutaminase family
CJO35_RS08385	COG4838	Belongs to the UPF0358 family
CJO35_RS08390	COG0772	Belongs to the SEDS family
CJO35_RS08395	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CJO35_RS08400	COG1612	heme a metabolic process
CJO35_RS08405	COG0109	protoheme IX farnesyltransferase activity
CJO35_RS08410	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CJO35_RS08410	COG2010	Cytochrome c
CJO35_RS08415	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CJO35_RS08420	COG1845	cytochrome c oxidase, subunit III
CJO35_RS08425	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CJO35_RS08430	COG3336	cytochrome c oxidase
CJO35_RS08440	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CJO35_RS08445	COG2340	Cysteine-rich secretory protein family
CJO35_RS08460	COG3679	Belongs to the UPF0342 family
CJO35_RS08465	COG4471	UPF0298 protein
CJO35_RS08470	COG0742	ribosomal rna small subunit methyltransferase
CJO35_RS08475	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CJO35_RS08480	COG3314	Sporulation integral membrane protein YlbJ
CJO35_RS08485	COG3480	Lon protease (S16) C-terminal proteolytic domain
CJO35_RS08490	COG1323	Belongs to the UPF0348 family
CJO35_RS08495	COG1399	metal-binding, possibly nucleic acid-binding protein
CJO35_RS08500	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CJO35_RS08510	COG0454	-acetyltransferase
CJO35_RS08515	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CJO35_RS08520	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
CJO35_RS08525	COG2001	Belongs to the MraZ family
CJO35_RS08530	COG0275	rRNA processing
CJO35_RS08535	COG4839	cell division protein FtsL
CJO35_RS08540	COG0768	penicillin binding
CJO35_RS08545	COG0768	penicillin binding
CJO35_RS08550	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CJO35_RS08555	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CJO35_RS08560	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CJO35_RS08565	COG0772	Belongs to the SEDS family
CJO35_RS08570	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CJO35_RS08575	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CJO35_RS08580	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CJO35_RS08585	COG3879	Bacterial protein of unknown function (DUF881)
CJO35_RS08590	COG3879	Bacterial protein of unknown function (DUF881)
CJO35_RS08595	COG3856	small basic protein
CJO35_RS08600	COG0849	cell division
CJO35_RS08605	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CJO35_RS08610	COG4412	M6 family metalloprotease domain protein
CJO35_RS08610	COG1404	Belongs to the peptidase S8 family
CJO35_RS08615	COG4412	M6 family metalloprotease domain protein
CJO35_RS08615	COG1404	Belongs to the peptidase S8 family
CJO35_RS08625	COG1191	sigma factor activity
CJO35_RS08630	COG1191	sigma factor activity
CJO35_RS08635	COG1119	ATPase activity
CJO35_RS08640	COG0500	methyltransferase
CJO35_RS08645	COG1873	PFAM PRC-barrel domain
CJO35_RS08650	COG1496	oxidoreductase activity
CJO35_RS08655	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CJO35_RS08660	COG1799	cell septum assembly
CJO35_RS08665	COG0762	integral membrane protein
CJO35_RS08670	COG2302	S4 RNA-binding domain
CJO35_RS08675	COG3599	regulation of cell shape
CJO35_RS08680	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CJO35_RS08685	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CJO35_RS08690	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CJO35_RS08695	COG0564	pseudouridine synthase activity
CJO35_RS08700	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CJO35_RS08705	COG2233	PERMEase
CJO35_RS08710	COG0540	Belongs to the ATCase OTCase family
CJO35_RS08715	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CJO35_RS08720	COG0505	Belongs to the CarA family
CJO35_RS08725	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CJO35_RS08730	COG0543	2 iron, 2 sulfur cluster binding
CJO35_RS08735	COG0167	dihydroorotate dehydrogenase activity
CJO35_RS08740	COG0284	orotidine-5'-phosphate decarboxylase activity
CJO35_RS08745	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CJO35_RS08755	COG0175	sulfate reduction
CJO35_RS08760	COG0306	phosphate transporter
CJO35_RS08765	COG2046	Belongs to the sulfate adenylyltransferase family
CJO35_RS08770	COG0529	Catalyzes the synthesis of activated sulfate
CJO35_RS08775	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CJO35_RS08780	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
CJO35_RS08785	COG1648	precorrin-2 dehydrogenase activity
CJO35_RS08795	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CJO35_RS08800	COG1561	YicC-like family, N-terminal region
CJO35_RS08805	COG2052	Domain of unknown function (DUF370)
CJO35_RS08810	COG0194	GDP metabolic process
CJO35_RS08815	COG1758	RNA polymerase activity
CJO35_RS08820	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CJO35_RS08825	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CJO35_RS08830	COG0242	peptide deformylase activity
CJO35_RS08835	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CJO35_RS08840	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CJO35_RS08840	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CJO35_RS08845	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CJO35_RS08850	COG0631	protein serine/threonine phosphatase activity
CJO35_RS08855	COG2815	serine threonine protein kinase
CJO35_RS08855	COG0515	serine threonine protein kinase
CJO35_RS08860	COG1162	GTPase activity
CJO35_RS08865	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CJO35_RS08870	COG1564	THIamine pyrophosphokinase
CJO35_RS08880	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CJO35_RS08885	COG1302	Protein conserved in bacteria
CJO35_RS08890	COG1461	Dihydroxyacetone kinase
CJO35_RS08895	COG1760	l-serine dehydratase
CJO35_RS08900	COG1760	l-serine dehydratase
CJO35_RS08905	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CJO35_RS08910	COG1349	DNA-binding transcription factor activity
CJO35_RS08915	COG0416	fatty acid biosynthetic process
CJO35_RS08920	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CJO35_RS08925	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_RS08930	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CJO35_RS08935	COG0571	ribonuclease III activity
CJO35_RS08940	COG1196	nuclear chromosome segregation
CJO35_RS08945	COG0552	protein localization to endoplasmic reticulum
CJO35_RS08950	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CJO35_RS08955	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CJO35_RS08960	COG0228	four-way junction DNA binding
CJO35_RS08965	COG1837	Belongs to the UPF0109 family
CJO35_RS08975	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CJO35_RS08980	COG0336	Belongs to the RNA methyltransferase TrmD family
CJO35_RS08985	COG0335	large ribosomal subunit rRNA binding
CJO35_RS08990	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CJO35_RS08995	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CJO35_RS09005	COG2257	FlhB HrpN YscU SpaS Family
CJO35_RS09010	COG0045	succinate-CoA ligase (ADP-forming) activity
CJO35_RS09015	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CJO35_RS09020	COG0758	DNA mediated transformation
CJO35_RS09025	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CJO35_RS09030	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CJO35_RS09035	COG4974	Belongs to the 'phage' integrase family
CJO35_RS09040	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CJO35_RS09045	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CJO35_RS09050	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CJO35_RS09055	COG1815	bacterial-type flagellum-dependent cell motility
CJO35_RS09060	COG1558	bacterial-type flagellum-dependent cell motility
CJO35_RS09065	COG1677	Flagellar hook-basal body complex protein FliE
CJO35_RS09070	COG1766	The M ring may be actively involved in energy transduction
CJO35_RS09075	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CJO35_RS09080	COG1317	bacterial-type flagellum organization
CJO35_RS09085	COG1157	protein secretion by the type III secretion system
CJO35_RS09090	COG2882	bacterial-type flagellum organization
CJO35_RS09100	COG3144	bacterial-type flagellum assembly
CJO35_RS09105	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CJO35_RS09110	COG4786	Flagellar basal body rod
CJO35_RS09115	COG1582	Flagellar protein (FlbD)
CJO35_RS09120	COG1580	Controls the rotational direction of flagella during chemotaxis
CJO35_RS09125	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CJO35_RS09130	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CJO35_RS09130	COG1776	CheC inhibitor of MCP methylation
CJO35_RS09135	COG2201	protein-glutamate methylesterase activity
CJO35_RS09140	COG3190	flagellar
CJO35_RS09145	COG1338	Plays a role in the flagellum-specific transport system
CJO35_RS09150	COG1987	bacterial-type flagellum assembly
CJO35_RS09155	COG1684	flagellar biosynthetic protein fliR
CJO35_RS09160	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CJO35_RS09165	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CJO35_RS09170	COG1419	protein localization to endoplasmic reticulum
CJO35_RS09175	COG0455	bacterial-type flagellum organization
CJO35_RS09180	COG2201	protein-glutamate methylesterase activity
CJO35_RS09185	COG0643	Histidine kinase
CJO35_RS09185	COG2198	Histidine kinase
CJO35_RS09190	COG0835	chemotaxis
CJO35_RS09195	COG1776	CheC inhibitor of MCP methylation
CJO35_RS09200	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CJO35_RS09205	COG1191	sigma factor activity
CJO35_RS09215	COG0052	Belongs to the universal ribosomal protein uS2 family
CJO35_RS09220	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CJO35_RS09225	COG0528	UMP kinase activity
CJO35_RS09230	COG0233	cytoplasmic translational termination
CJO35_RS09235	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CJO35_RS09240	COG4589	Belongs to the CDS family
CJO35_RS09245	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CJO35_RS09250	COG0750	zinc metalloprotease
CJO35_RS09255	COG0442	prolyl-tRNA aminoacylation
CJO35_RS09260	COG2176	DNA-directed DNA polymerase activity
CJO35_RS09290	COG0779	Required for maturation of 30S ribosomal subunits
CJO35_RS09295	COG0195	Participates in both transcription termination and antitermination
CJO35_RS09300	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CJO35_RS09305	COG1358	cellular component organization or biogenesis
CJO35_RS09310	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CJO35_RS09315	COG1550	Protein conserved in bacteria
CJO35_RS09320	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CJO35_RS09325	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CJO35_RS09330	COG0196	riboflavin kinase activity
CJO35_RS09335	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CJO35_RS09340	COG1185	polyribonucleotide nucleotidyltransferase activity
CJO35_RS09345	COG0726	polysaccharide deacetylase
CJO35_RS09350	COG0612	Peptidase, M16
CJO35_RS09355	COG1873	PFAM PRC-barrel domain
CJO35_RS09360	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CJO35_RS09365	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CJO35_RS09370	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CJO35_RS09375	COG0527	aspartate kinase activity
CJO35_RS09385	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CJO35_RS09390	COG0740	serine-type endopeptidase activity
CJO35_RS09400	COG4980	gas vesicle protein
CJO35_RS09400	COG1674	ftsk spoiiie
CJO35_RS09405	COG2188	Transcriptional regulator
CJO35_RS09410	COG2814	Major facilitator Superfamily
CJO35_RS09415	COG0612	Peptidase, M16
CJO35_RS09420	COG0612	Peptidase, M16
CJO35_RS09425	COG0300	oxidoreductase activity
CJO35_RS09440	COG1426	Protein conserved in bacteria
CJO35_RS09445	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CJO35_RS09450	COG1546	Belongs to the CinA family
CJO35_RS09450	COG1058	Belongs to the CinA family
CJO35_RS09460	COG1418	mRNA catabolic process
CJO35_RS09465	COG1692	metallophosphoesterase
CJO35_RS09470	COG2359	stage V sporulation protein S
CJO35_RS09480	COG1063	alcohol dehydrogenase
CJO35_RS09485	COG0156	8-amino-7-oxononanoate synthase activity
CJO35_RS09490	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CJO35_RS09495	COG4550	Control of competence regulator ComK, YlbF/YmcA
CJO35_RS09505	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CJO35_RS09510	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CJO35_RS09515	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CJO35_RS09520	COG5444	nuclease activity
CJO35_RS09540	COG0523	cobalamin synthesis protein
CJO35_RS09550	COG1247	-acetyltransferase
CJO35_RS09570	COG3619	membrane
CJO35_RS09575	COG3263	regulation of cellular component size
CJO35_RS09580	COG2814	Major facilitator Superfamily
CJO35_RS09585	COG2814	Major facilitator Superfamily
CJO35_RS09590	COG2814	Major facilitator Superfamily
CJO35_RS09595	COG2267	carboxylic ester hydrolase activity
CJO35_RS09600	COG2267	carboxylic ester hydrolase activity
CJO35_RS09610	COG0393	Putative heavy-metal-binding
CJO35_RS09615	COG0398	Pfam SNARE associated Golgi protein
CJO35_RS09620	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CJO35_RS09625	COG1819	glycosyl
CJO35_RS09630	COG0531	amino acid
CJO35_RS09635	COG5577	PFAM Coat F domain
CJO35_RS09645	COG3858	chitin binding
CJO35_RS09645	COG1388	LysM domain
CJO35_RS09650	COG1309	transcriptional regulator
CJO35_RS09655	COG3631	Ketosteroid isomerase-related protein
CJO35_RS09660	COG0702	epimerase
CJO35_RS09670	COG1764	response to oxidative stress
CJO35_RS09675	COG2076	Multidrug Resistance protein
CJO35_RS09680	COG2076	Multidrug Resistance protein
CJO35_RS09695	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CJO35_RS09700	COG1923	regulation of RNA biosynthetic process
CJO35_RS09715	COG1780	Probably involved in ribonucleotide reductase function
CJO35_RS09720	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CJO35_RS09725	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CJO35_RS09730	COG4112	unkown
CJO35_RS09745	COG0735	belongs to the Fur family
CJO35_RS09750	COG1802	Transcriptional regulator
CJO35_RS09755	COG0697	spore germination
CJO35_RS09790	COG1309	transcriptional regulator
CJO35_RS09845	COG0464	growth
CJO35_RS09850	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CJO35_RS09855	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CJO35_RS09860	COG0789	Transcriptional regulator
CJO35_RS09865	COG0174	glutamine synthetase
CJO35_RS09910	COG1073	alpha beta
CJO35_RS09950	COG1309	transcriptional regulator
CJO35_RS09955	COG2076	Multidrug Resistance protein
CJO35_RS09960	COG2076	Multidrug Resistance protein
CJO35_RS09965	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CJO35_RS09980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CJO35_RS09985	COG3546	catalase activity
CJO35_RS10010	COG1846	Transcriptional regulator
CJO35_RS10015	COG0778	Nitroreductase
CJO35_RS10020	COG0346	lactoylglutathione lyase activity
CJO35_RS10025	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CJO35_RS10030	COG0655	NAD(P)H dehydrogenase (quinone) activity
CJO35_RS10050	COG3209	COG3209 Rhs family protein
CJO35_RS10055	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CJO35_RS10060	COG1388	LysM domain
CJO35_RS10065	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CJO35_RS10070	COG4224	UPF0291 protein
CJO35_RS10075	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CJO35_RS10085	COG3763	UPF0154 protein
CJO35_RS10095	COG0785	Cytochrome C biogenesis protein
CJO35_RS10100	COG2201	protein-glutamate methylesterase activity
CJO35_RS10105	COG4846	Membrane protein involved in cytochrome C biogenesis
CJO35_RS10115	COG0071	Belongs to the small heat shock protein (HSP20) family
CJO35_RS10130	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CJO35_RS10135	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CJO35_RS10155	COG0824	Thioesterase
CJO35_RS10180	COG4841	protein insertion into membrane
CJO35_RS10185	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CJO35_RS10190	COG1832	CoA-binding protein
CJO35_RS10195	COG0187	DNA topoisomerase II activity
CJO35_RS10200	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CJO35_RS10205	COG1609	Transcriptional regulator
CJO35_RS10220	COG2160	L-arabinose isomerase activity
CJO35_RS10240	COG1115	amino acid carrier protein
CJO35_RS10250	COG2181	nitrate reductase activity
CJO35_RS10255	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CJO35_RS10260	COG1140	nitrate reductase beta subunit
CJO35_RS10265	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CJO35_RS10280	COG0535	radical SAM domain protein
CJO35_RS10285	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CJO35_RS10295	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CJO35_RS10300	COG2223	nitrite transmembrane transporter activity
CJO35_RS10320	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
CJO35_RS10330	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CJO35_RS10340	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CJO35_RS10365	COG3420	alginic acid biosynthetic process
CJO35_RS10370	COG1114	Component of the transport system for branched-chain amino acids
CJO35_RS10380	COG0789	Transcriptional regulator
CJO35_RS10405	COG1024	Enoyl-CoA hydratase
CJO35_RS10410	COG1012	belongs to the aldehyde dehydrogenase family
CJO35_RS10415	COG2084	Dehydrogenase
CJO35_RS10420	COG1960	acyl-CoA dehydrogenase activity
CJO35_RS10425	COG1482	cell wall glycoprotein biosynthetic process
CJO35_RS10430	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CJO35_RS10430	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CJO35_RS10430	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CJO35_RS10450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CJO35_RS10450	COG3711	transcriptional antiterminator
CJO35_RS10465	COG1725	Transcriptional regulator
CJO35_RS10470	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_RS10475	COG1312	Catalyzes the dehydration of D-mannonate
CJO35_RS10490	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CJO35_RS10500	COG1609	Transcriptional regulator
CJO35_RS10505	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CJO35_RS10510	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CJO35_RS10515	COG0640	Transcriptional regulator
CJO35_RS10525	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
CJO35_RS10540	COG1649	PFAM Uncharacterised BCR, COG1649
CJO35_RS10545	COG2404	hydrolase activity, acting on ester bonds
CJO35_RS10550	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CJO35_RS10560	COG2027	D-alanyl-D-alanine carboxypeptidase
CJO35_RS10565	COG1252	NADH dehydrogenase
CJO35_RS10580	COG0166	Belongs to the GPI family
CJO35_RS10590	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CJO35_RS10595	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CJO35_RS10600	COG1024	Enoyl-CoA hydratase
CJO35_RS10605	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CJO35_RS10610	COG0511	ligase activity, forming carbon-carbon bonds
CJO35_RS10615	COG0439	Biotin carboxylase
CJO35_RS10620	COG0318	PFAM AMP-dependent synthetase and ligase
CJO35_RS10625	COG1960	acyl-CoA dehydrogenase activity
CJO35_RS10630	COG2249	NAD(P)H dehydrogenase (quinone) activity
CJO35_RS10635	COG1733	regulation of RNA biosynthetic process
CJO35_RS10640	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CJO35_RS10645	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CJO35_RS10655	COG2323	membrane
CJO35_RS10665	COG0306	phosphate transporter
CJO35_RS10670	COG0175	sulfate reduction
CJO35_RS10675	COG1809	phosphosulfolactate synthase activity
CJO35_RS10680	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CJO35_RS10685	COG4948	Mandelate Racemase Muconate Lactonizing
CJO35_RS10690	COG2814	Major facilitator Superfamily
CJO35_RS10695	COG0463	Glycosyl transferase, family 2
CJO35_RS10710	COG0493	'glutamate synthase
CJO35_RS10715	COG0069	glutamate synthase activity
CJO35_RS10715	COG0070	glutamate synthase
CJO35_RS10715	COG0067	glutamate synthase
CJO35_RS10720	COG0583	DNA-binding transcription factor activity
CJO35_RS10740	COG1846	Transcriptional regulator
CJO35_RS10750	COG1132	(ABC) transporter
CJO35_RS10760	COG0300	oxidoreductase activity
CJO35_RS10765	COG3848	Pyruvate phosphate dikinase
CJO35_RS10765	COG0574	Belongs to the PEP-utilizing enzyme family
CJO35_RS10775	COG0477	Major facilitator Superfamily
CJO35_RS10780	COG0243	molybdopterin cofactor binding
CJO35_RS10785	COG1846	Transcriptional regulator
CJO35_RS10795	COG0531	amino acid
CJO35_RS10805	COG0531	amino acid
CJO35_RS10810	COG0531	amino acid
CJO35_RS10815	COG0697	spore germination
CJO35_RS10825	COG0488	(ABC) transporter
CJO35_RS10830	COG0840	transmembrane signaling receptor activity
CJO35_RS10835	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CJO35_RS10840	COG1404	Belongs to the peptidase S8 family
CJO35_RS10850	COG1309	transcriptional regulator
CJO35_RS10855	COG1846	Transcriptional regulator
CJO35_RS10885	COG1309	transcriptional regulator
CJO35_RS10905	COG2378	regulation of single-species biofilm formation
CJO35_RS10915	COG0640	Transcriptional regulator
CJO35_RS10920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CJO35_RS10930	COG0531	amino acid
CJO35_RS10935	COG0741	lytic transglycosylase activity
CJO35_RS10940	COG1086	Polysaccharide biosynthesis protein
CJO35_RS10960	COG2322	membrane
CJO35_RS10975	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CJO35_RS10980	COG1388	LysM domain
CJO35_RS10980	COG3584	3D domain protein
CJO35_RS10985	COG0514	ATP-dependent DNA helicase (RecQ)
CJO35_RS11025	COG2427	Protein of unknown function (DUF1641)
CJO35_RS11030	COG3383	formate dehydrogenase (NAD+) activity
CJO35_RS11055	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CJO35_RS11100	COG0402	S-adenosylhomocysteine deaminase activity
CJO35_RS11115	COG2267	carboxylic ester hydrolase activity
CJO35_RS11130	COG1280	lysine exporter protein (LysE YggA)
CJO35_RS11135	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CJO35_RS11145	COG0574	Belongs to the PEP-utilizing enzyme family
CJO35_RS11145	COG3848	Pyruvate phosphate dikinase
CJO35_RS11150	COG1309	transcriptional regulator
CJO35_RS11165	COG2318	DinB family
CJO35_RS11170	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CJO35_RS11175	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CJO35_RS11190	COG1012	belongs to the aldehyde dehydrogenase family
CJO35_RS11195	COG2814	Major facilitator Superfamily
CJO35_RS11210	COG1657	PFAM Prenyltransferase squalene oxidase
CJO35_RS11215	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CJO35_RS11225	COG0733	neurotransmitter:sodium symporter activity
CJO35_RS11230	COG0385	Bile acid
CJO35_RS11235	COG0508	dehydrogenase complex catalyzes the overall conversion of
CJO35_RS11240	COG0567	Dehydrogenase, E1 component
CJO35_RS11245	COG4548	von Willebrand factor, type A
CJO35_RS11250	COG0714	Associated with various cellular activities
CJO35_RS11255	COG2032	superoxide dismutase activity
CJO35_RS11260	COG1388	LysM domain
CJO35_RS11260	COG0791	NLP P60 protein
CJO35_RS11270	COG0534	Mate efflux family protein
CJO35_RS11275	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CJO35_RS11280	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CJO35_RS11290	COG2962	Rard protein
CJO35_RS11300	COG4305	rare lipoprotein A
CJO35_RS11315	COG1733	regulation of RNA biosynthetic process
CJO35_RS11320	COG0778	Nitroreductase
CJO35_RS11325	COG0400	carboxylic ester hydrolase activity
CJO35_RS11335	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CJO35_RS11340	COG0793	Belongs to the peptidase S41A family
CJO35_RS11340	COG3409	Peptidoglycan-binding domain 1 protein
CJO35_RS11345	COG2226	methyltransferase
CJO35_RS11355	COG1876	peptidase activity
CJO35_RS11360	COG0813	purine-nucleoside phosphorylase activity
CJO35_RS11365	COG0701	Predicted permease
CJO35_RS11385	COG0671	phosphoesterase, PA-phosphatase related
CJO35_RS11405	COG4479	Belongs to the UPF0346 family
CJO35_RS11415	COG1509	lysine 2,3-aminomutase activity
CJO35_RS11420	COG0456	acetyltransferase
CJO35_RS11425	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CJO35_RS11430	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CJO35_RS11435	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CJO35_RS11440	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CJO35_RS11455	COG0456	acetyltransferase
CJO35_RS11460	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CJO35_RS11465	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CJO35_RS11470	COG1846	Transcriptional regulator
CJO35_RS11480	COG3706	GGDEF domain
CJO35_RS11485	COG0534	Mate efflux family protein
CJO35_RS11500	COG4698	Protein conserved in bacteria
CJO35_RS11505	COG2755	lipolytic protein G-D-S-L family
CJO35_RS11510	COG1999	signal sequence binding
CJO35_RS11525	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CJO35_RS11530	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CJO35_RS11535	COG1272	protein, Hemolysin III
CJO35_RS11540	COG0204	Acyl-transferase
CJO35_RS11545	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CJO35_RS11550	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CJO35_RS11560	COG2521	methyltransferase
CJO35_RS11560	COG2136	Putative SAM-dependent methyltransferase
CJO35_RS11570	COG0129	dihydroxy-acid dehydratase activity
CJO35_RS11575	COG1413	lyase activity
CJO35_RS11580	COG1418	mRNA catabolic process
CJO35_RS11585	COG0386	Belongs to the glutathione peroxidase family
CJO35_RS11590	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CJO35_RS11595	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CJO35_RS11600	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CJO35_RS11610	COG1278	Cold shock
CJO35_RS11630	COG0328	RNA-DNA hybrid ribonuclease activity
CJO35_RS11635	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CJO35_RS11640	COG0328	RNA-DNA hybrid ribonuclease activity
CJO35_RS11650	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CJO35_RS11665	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CJO35_RS11675	COG1755	Isoprenylcysteine carboxyl methyltransferase
CJO35_RS11680	COG3424	synthase
CJO35_RS11685	COG0456	acetyltransferase
CJO35_RS11690	COG2233	PERMEase
CJO35_RS11695	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CJO35_RS11700	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CJO35_RS11705	COG1199	ATP-dependent helicase activity
CJO35_RS11720	COG0116	Belongs to the methyltransferase superfamily
CJO35_RS11730	COG3599	regulation of cell shape
CJO35_RS11735	COG4474	Belongs to the UPF0398 family
CJO35_RS11745	COG3359	exonuclease
CJO35_RS11750	COG1205	dead DEAH box helicase
CJO35_RS11750	COG1111	helicase
CJO35_RS11755	COG2190	(PTS) system
CJO35_RS11760	COG0071	Belongs to the small heat shock protein (HSP20) family
CJO35_RS11795	COG3331	DNA recombination
CJO35_RS11800	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CJO35_RS11800	COG4499	WXG100 protein secretion system (Wss), protein YukC
CJO35_RS11810	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CJO35_RS11815	COG3935	DnaD domain protein
CJO35_RS11820	COG0017	Asparaginyl-tRNA synthetase
CJO35_RS11825	COG0436	Aminotransferase
CJO35_RS11830	COG5353	protein conserved in bacteria
CJO35_RS11840	COG1199	ATP-dependent helicase activity
CJO35_RS11840	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CJO35_RS11845	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CJO35_RS11850	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CJO35_RS11855	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CJO35_RS11870	COG0617	tRNA 3'-terminal CCA addition
CJO35_RS11875	COG0438	transferase activity, transferring glycosyl groups
CJO35_RS11880	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CJO35_RS11885	COG1803	Methylglyoxal synthase
CJO35_RS11890	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CJO35_RS11895	COG1694	Mazg nucleotide pyrophosphohydrolase
CJO35_RS11900	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CJO35_RS11910	COG4347	Protein of unknown function (DUF1405)
CJO35_RS11915	COG2010	Cytochrome c
CJO35_RS11915	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CJO35_RS11920	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CJO35_RS11925	COG0723	plastoquinol--plastocyanin reductase activity
CJO35_RS11935	COG5582	Belongs to the UPF0302 family
CJO35_RS11940	COG0457	Tetratricopeptide repeat
CJO35_RS11945	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CJO35_RS11950	COG0287	Prephenate dehydrogenase
CJO35_RS11955	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CJO35_RS11960	COG0159	tryptophan synthase activity
CJO35_RS11965	COG0133	tryptophan synthase activity
CJO35_RS11970	COG0135	phosphoribosylanthranilate isomerase activity
CJO35_RS11975	COG0134	indole-3-glycerol-phosphate synthase activity
CJO35_RS11980	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CJO35_RS11985	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CJO35_RS11990	COG4401	Chorismate mutase type I
CJO35_RS11995	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CJO35_RS12000	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CJO35_RS12005	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CJO35_RS12010	COG0105	UTP biosynthetic process
CJO35_RS12015	COG0142	geranyltranstransferase activity
CJO35_RS12020	COG2226	methyltransferase
CJO35_RS12025	COG0142	geranyltranstransferase activity
CJO35_RS12040	COG0776	regulation of translation
CJO35_RS12045	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CJO35_RS12065	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CJO35_RS12070	COG1160	GTP binding
CJO35_RS12095	COG1304	FMN binding
CJO35_RS12100	COG0539	negative regulation of cytoplasmic translation
CJO35_RS12105	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CJO35_RS12115	COG2959	enzyme of heme biosynthesis
CJO35_RS12120	COG3773	Cell wall hydrolase
CJO35_RS12120	COG3409	Peptidoglycan-binding domain 1 protein
CJO35_RS12125	COG2339	peptidase activity
CJO35_RS12135	COG0492	ferredoxin-NADP+ reductase activity
CJO35_RS12140	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CJO35_RS12145	COG4862	establishment of competence for transformation
CJO35_RS12150	COG1408	metallophosphoesterase
CJO35_RS12160	COG1388	LysM domain
CJO35_RS12165	COG1266	CAAX protease self-immunity
CJO35_RS12170	COG0514	ATP-dependent DNA helicase (RecQ)
CJO35_RS12175	COG4955	Helix-turn-helix domain
CJO35_RS12180	COG1141	Ferredoxin
CJO35_RS12185	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CJO35_RS12190	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CJO35_RS12195	COG0739	heme binding
CJO35_RS12205	COG1595	DNA-templated transcription, initiation
CJO35_RS12210	COG1316	TRANSCRIPTIONal
CJO35_RS12225	COG5002	protein histidine kinase activity
CJO35_RS12230	COG0745	RESPONSE REGULATOR receiver
CJO35_RS12235	COG5002	protein histidine kinase activity
CJO35_RS12240	COG0745	RESPONSE REGULATOR receiver
CJO35_RS12245	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CJO35_RS12250	COG1333	cytochrome c biogenesis protein
CJO35_RS12255	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CJO35_RS12260	COG1187	pseudouridine synthase activity
CJO35_RS12265	COG0700	Nucleoside recognition
CJO35_RS12270	COG2715	membrane protein required for spore maturation
CJO35_RS12275	COG1686	Belongs to the peptidase S11 family
CJO35_RS12285	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CJO35_RS12290	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CJO35_RS12300	COG1547	Domain of unknown function (DUF309)
CJO35_RS12305	COG0456	acetyltransferase
CJO35_RS12310	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CJO35_RS12315	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CJO35_RS12315	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CJO35_RS12320	COG0307	riboflavin synthase, alpha
CJO35_RS12325	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CJO35_RS12325	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CJO35_RS12350	COG0457	Tetratricopeptide repeat
CJO35_RS12355	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CJO35_RS12360	COG4086	secreted protein
CJO35_RS12365	COG4195	phage-related replication protein
CJO35_RS12370	COG0019	diaminopimelate decarboxylase activity
CJO35_RS12380	COG0697	spore germination
CJO35_RS12395	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CJO35_RS12430	COG1686	Belongs to the peptidase S11 family
CJO35_RS12435	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CJO35_RS12440	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CJO35_RS12445	COG4974	Belongs to the 'phage' integrase family
CJO35_RS12455	COG0735	belongs to the Fur family
CJO35_RS12460	COG1300	Membrane
CJO35_RS12465	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CJO35_RS12485	COG2153	protein acetylation
CJO35_RS12490	COG1379	DNA repair
CJO35_RS12495	COG0494	nUDIX hydrolase
CJO35_RS12505	COG1309	transcriptional regulator
CJO35_RS12515	COG0667	Aldo Keto reductase
CJO35_RS12525	COG1073	alpha beta
CJO35_RS12535	COG4918	Iron-sulphur cluster biosynthesis
CJO35_RS12550	COG2329	Antibiotic biosynthesis monooxygenase
CJO35_RS12560	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CJO35_RS12570	COG0747	negative chemotaxis
CJO35_RS12575	COG0601	transmembrane transport
CJO35_RS12585	COG0444	Belongs to the ABC transporter superfamily
CJO35_RS12595	COG0534	Mate efflux family protein
CJO35_RS12610	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CJO35_RS12620	COG2211	Major facilitator Superfamily
CJO35_RS12625	COG0346	lactoylglutathione lyase activity
CJO35_RS12630	COG1072	(Pantothenic acid kinase))
CJO35_RS12645	COG1131	(ABC) transporter
CJO35_RS12665	COG4195	phage-related replication protein
CJO35_RS12675	COG0300	oxidoreductase activity
CJO35_RS12680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CJO35_RS12685	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CJO35_RS12690	COG4187	Peptidase family M20/M25/M40
CJO35_RS12695	COG1902	pentaerythritol trinitrate reductase activity
CJO35_RS12700	COG0596	Alpha beta hydrolase
CJO35_RS12705	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CJO35_RS12710	COG1234	tRNA 3'-trailer cleavage
CJO35_RS12715	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CJO35_RS12730	COG2358	TRAP transporter, solute receptor (TAXI family
CJO35_RS12735	COG2188	Transcriptional regulator
CJO35_RS12740	COG2723	6-phospho-beta-galactosidase activity
CJO35_RS12745	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CJO35_RS12750	COG1447	Phosphotransferase system cellobiose-specific component IIA
CJO35_RS12755	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CJO35_RS12760	COG1785	Belongs to the alkaline phosphatase family
CJO35_RS12765	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_RS12770	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CJO35_RS12775	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CJO35_RS12785	COG0706	membrane insertase activity
CJO35_RS12790	COG2195	Cleaves the N-terminal amino acid of tripeptides
CJO35_RS12795	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CJO35_RS12800	COG4129	membrane
CJO35_RS12805	COG1126	abc transporter atp-binding protein
CJO35_RS12810	COG0765	amino acid transport
CJO35_RS12815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CJO35_RS12825	COG1597	lipid kinase activity
CJO35_RS12830	COG0508	dehydrogenase complex catalyzes the overall conversion of
CJO35_RS12835	COG0022	dehydrogenase e1 component
CJO35_RS12840	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CJO35_RS12845	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CJO35_RS12850	COG3426	butyrate kinase activity
CJO35_RS12860	COG0280	phosphate acetyltransferase
CJO35_RS12865	COG3290	protein histidine kinase activity
CJO35_RS12865	COG3829	transcription factor binding
CJO35_RS12875	COG0584	glycerophosphoryl diester phosphodiesterase
CJO35_RS12880	COG0860	N-Acetylmuramoyl-L-alanine amidase
CJO35_RS12895	COG1045	serine acetyltransferase
CJO35_RS12905	COG0745	RESPONSE REGULATOR receiver
CJO35_RS12910	COG0750	zinc metalloprotease
CJO35_RS12915	COG0497	DNA recombination
CJO35_RS12920	COG1438	arginine binding
CJO35_RS12925	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CJO35_RS12930	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CJO35_RS12935	COG0142	geranyltranstransferase activity
CJO35_RS12940	COG1722	exodeoxyribonuclease VII activity
CJO35_RS12945	COG1570	exodeoxyribonuclease VII activity
CJO35_RS12950	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CJO35_RS12955	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CJO35_RS12960	COG1302	Protein conserved in bacteria
CJO35_RS12965	COG0439	Biotin carboxylase
CJO35_RS12970	COG0511	ligase activity, forming carbon-carbon bonds
CJO35_RS13010	COG3854	ATPases associated with a variety of cellular activities
CJO35_RS13020	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CJO35_RS13025	COG0006	proline dipeptidase activity
CJO35_RS13030	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CJO35_RS13040	COG3872	metal-dependent enzyme
CJO35_RS13050	COG1752	Esterase of the alpha-beta hydrolase superfamily
CJO35_RS13055	COG1321	iron dependent repressor
CJO35_RS13060	COG0095	Lipoate-protein ligase
CJO35_RS13065	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CJO35_RS13070	COG2113	Glycine betaine
CJO35_RS13075	COG4176	ABC-type proline glycine betaine transport system permease component
CJO35_RS13080	COG0517	IMP dehydrogenase activity
CJO35_RS13080	COG4175	Glycine betaine
CJO35_RS13085	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CJO35_RS13090	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CJO35_RS13095	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CJO35_RS13100	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CJO35_RS13125	COG0681	Belongs to the peptidase S26 family
CJO35_RS13150	COG4940	Competence protein ComGF
CJO35_RS13160	COG4970	Tfp pilus assembly protein FimT
CJO35_RS13165	COG4537	Required for transformation and DNA binding
CJO35_RS13170	COG1459	type II secretion system
CJO35_RS13175	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CJO35_RS13180	COG1366	Belongs to the anti-sigma-factor antagonist family
CJO35_RS13190	COG1393	Belongs to the ArsC family
CJO35_RS13200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CJO35_RS13210	COG0011	TIGRFAM Protein of
CJO35_RS13220	COG2866	Carboxypeptidase
CJO35_RS13225	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CJO35_RS13230	COG1368	sulfuric ester hydrolase activity
CJO35_RS13235	COG1940	carbohydrate kinase activity
CJO35_RS13240	COG4483	Protein conserved in bacteria
CJO35_RS13245	COG0697	spore germination
CJO35_RS13250	COG0705	Rhomboid family
CJO35_RS13250	COG0457	Tetratricopeptide repeat
CJO35_RS13260	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CJO35_RS13265	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CJO35_RS13270	COG0438	transferase activity, transferring glycosyl groups
CJO35_RS13285	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CJO35_RS13290	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CJO35_RS13295	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CJO35_RS13300	COG0581	inorganic phosphate transmembrane transporter activity
CJO35_RS13305	COG0573	inorganic phosphate transmembrane transporter activity
CJO35_RS13310	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CJO35_RS13315	COG0768	penicillin binding
CJO35_RS13320	COG0477	Major facilitator Superfamily
CJO35_RS13325	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CJO35_RS13330	COG2839	Protein conserved in bacteria
CJO35_RS13335	COG5521	maltodextrose utilization protein MalA
CJO35_RS13340	COG1388	LysM domain
CJO35_RS13345	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CJO35_RS13350	COG4709	membrane
CJO35_RS13355	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
CJO35_RS13360	COG0735	belongs to the Fur family
CJO35_RS13365	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CJO35_RS13370	COG1121	(ABC) transporter
CJO35_RS13375	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CJO35_RS13385	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CJO35_RS13390	COG0513	Belongs to the DEAD box helicase family
CJO35_RS13400	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CJO35_RS13405	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CJO35_RS13410	COG2384	SAM-dependent methyltransferase
CJO35_RS13465	COG5444	nuclease activity
CJO35_RS13480	COG2010	Cytochrome c
CJO35_RS13485	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CJO35_RS13490	COG0358	DNA primase activity
CJO35_RS13495	COG1671	Belongs to the UPF0178 family
CJO35_RS13500	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CJO35_RS13505	COG0517	IMP dehydrogenase activity
CJO35_RS13510	COG0751	glycine-tRNA ligase activity
CJO35_RS13515	COG0752	glycyl-tRNA synthetase alpha subunit
CJO35_RS13520	COG1381	Involved in DNA repair and RecF pathway recombination
CJO35_RS13530	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CJO35_RS13535	COG0295	cytidine deaminase activity
CJO35_RS13540	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CJO35_RS13545	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CJO35_RS13550	COG1480	7TM receptor with intracellular HD hydrolase
CJO35_RS13555	COG1702	phosphate starvation-inducible protein PhoH
CJO35_RS13560	COG0561	phosphatase activity
CJO35_RS13575	COG4864	UPF0365 protein
CJO35_RS13580	COG1030	water channel activity
CJO35_RS13585	COG1610	YqeY-like protein
CJO35_RS13590	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CJO35_RS13595	COG1283	sodium-dependent phosphate transmembrane transporter activity
CJO35_RS13600	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CJO35_RS13605	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CJO35_RS13610	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CJO35_RS13615	COG2264	protein methyltransferase activity
CJO35_RS13620	COG0484	heat shock protein binding
CJO35_RS13625	COG0443	Heat shock 70 kDa protein
CJO35_RS13630	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CJO35_RS13635	COG1420	regulation of RNA biosynthetic process
CJO35_RS13640	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CJO35_RS13645	COG0481	GTPase activity
CJO35_RS13655	COG0860	N-Acetylmuramoyl-L-alanine amidase
CJO35_RS13660	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CJO35_RS13665	COG0268	Binds directly to 16S ribosomal RNA
CJO35_RS13670	COG1466	dna polymerase III delta subunit
CJO35_RS13680	COG2333	competence protein COMEC
CJO35_RS13680	COG0658	competence protein
CJO35_RS13685	COG2131	deaminase
CJO35_RS13690	COG1596	polysaccharide export
CJO35_RS13690	COG1555	photosystem II stabilization
CJO35_RS13695	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CJO35_RS13700	COG2226	methyltransferase
CJO35_RS13705	COG0799	negative regulation of ribosome biogenesis
CJO35_RS13710	COG1713	HD superfamily hydrolase involved in NAD metabolism
CJO35_RS13715	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CJO35_RS13720	COG1534	Rna-binding protein
CJO35_RS13725	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CJO35_RS13730	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CJO35_RS13735	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CJO35_RS13745	COG2755	lipolytic protein G-D-S-L family
CJO35_RS13750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CJO35_RS13755	COG5609	conserved protein (DUF2294)
CJO35_RS13760	COG3383	formate dehydrogenase (NAD+) activity
CJO35_RS13765	COG2427	Protein of unknown function (DUF1641)
CJO35_RS13800	COG0860	N-Acetylmuramoyl-L-alanine amidase
CJO35_RS13865	COG2197	response regulator
CJO35_RS13870	COG4585	Histidine kinase
CJO35_RS13875	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CJO35_RS13880	COG0730	response to heat
CJO35_RS13885	COG0425	Belongs to the sulfur carrier protein TusA family
CJO35_RS13890	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CJO35_RS13890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CJO35_RS13895	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CJO35_RS13895	COG0425	Belongs to the sulfur carrier protein TusA family
CJO35_RS13900	COG2210	Belongs to the sulfur carrier protein TusA family
CJO35_RS13905	COG1937	Protein conserved in bacteria
CJO35_RS13945	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CJO35_RS13950	COG0113	porphobilinogen synthase activity
CJO35_RS13955	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CJO35_RS13960	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CJO35_RS13965	COG1733	regulation of RNA biosynthetic process
CJO35_RS13970	COG3239	Fatty acid desaturase
CJO35_RS13975	COG4585	Histidine kinase
CJO35_RS13980	COG2197	response regulator
CJO35_RS13985	COG0492	ferredoxin-NADP+ reductase activity
CJO35_RS13990	COG0747	negative chemotaxis
CJO35_RS13995	COG0601	transmembrane transport
CJO35_RS14000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CJO35_RS14005	COG0444	Belongs to the ABC transporter superfamily
CJO35_RS14010	COG4608	Belongs to the ABC transporter superfamily
CJO35_RS14030	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_RS14045	COG2124	cytochrome p450
CJO35_RS14050	COG0730	response to heat
CJO35_RS14065	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_RS14070	COG1621	beta-fructofuranosidase activity
CJO35_RS14075	COG3716	PTS system mannose fructose sorbose family IID component
CJO35_RS14080	COG3715	PTS system
CJO35_RS14085	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CJO35_RS14090	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CJO35_RS14095	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CJO35_RS14095	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CJO35_RS14120	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CJO35_RS14125	COG0656	L-ascorbic acid biosynthetic process
CJO35_RS14130	COG2814	Major facilitator Superfamily
CJO35_RS14135	COG1733	regulation of RNA biosynthetic process
CJO35_RS14140	COG3340	Belongs to the peptidase S51 family
CJO35_RS14145	COG1587	Uroporphyrinogen-III synthase
CJO35_RS14155	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CJO35_RS14160	COG0583	DNA-binding transcription factor activity
CJO35_RS14165	COG2814	Major facilitator Superfamily
CJO35_RS14175	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CJO35_RS14175	COG2124	cytochrome p450
CJO35_RS14180	COG1309	transcriptional regulator
CJO35_RS14185	COG1404	Belongs to the peptidase S8 family
CJO35_RS14190	COG2226	methyltransferase
CJO35_RS14215	COG0626	cystathionine gamma-synthase activity
CJO35_RS14220	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CJO35_RS14225	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CJO35_RS14230	COG2226	methyltransferase
CJO35_RS14245	COG0768	penicillin binding
CJO35_RS14250	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CJO35_RS14255	COG0572	uridine kinase
CJO35_RS14260	COG0826	peptidase U32
CJO35_RS14265	COG0826	peptidase U32
CJO35_RS14270	COG4122	O-methyltransferase activity
CJO35_RS14275	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CJO35_RS14280	COG3906	Belongs to the UPF0473 family
CJO35_RS14285	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CJO35_RS14290	COG4472	Bacterial protein of unknown function (DUF965)
CJO35_RS14295	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CJO35_RS14300	COG0628	permease
CJO35_RS14315	COG3881	PFAM PRC-barrel domain
CJO35_RS14320	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CJO35_RS14325	COG0457	Tetratricopeptide repeat
CJO35_RS14330	COG0482	sulfurtransferase activity
CJO35_RS14335	COG1104	cysteine desulfurase activity
CJO35_RS14340	COG1959	2 iron, 2 sulfur cluster binding
CJO35_RS14345	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CJO35_RS14350	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CJO35_RS14360	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CJO35_RS14365	COG0124	histidyl-tRNA synthetase
CJO35_RS14375	COG3103	Sh3 type 3 domain protein
CJO35_RS14375	COG0860	N-Acetylmuramoyl-L-alanine amidase
CJO35_RS14375	COG4991	sh3 domain protein
CJO35_RS14380	COG1490	D-aminoacyl-tRNA deacylase activity
CJO35_RS14385	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CJO35_RS14390	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CJO35_RS14395	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CJO35_RS14395	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CJO35_RS14400	COG5416	Lipopolysaccharide assembly protein A domain
CJO35_RS14405	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CJO35_RS14405	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CJO35_RS14415	COG2244	polysaccharide biosynthetic process
CJO35_RS14420	COG2323	membrane
CJO35_RS14430	COG1862	Preprotein translocase
CJO35_RS14435	COG0343	queuine tRNA-ribosyltransferase activity
CJO35_RS14440	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CJO35_RS14450	COG2255	four-way junction helicase activity
CJO35_RS14455	COG0632	four-way junction helicase activity
CJO35_RS14465	COG2112	serine threonine protein kinase
CJO35_RS14475	COG2318	DinB family
CJO35_RS14480	COG4195	phage-related replication protein
CJO35_RS14495	COG0217	transcriptional regulatory protein
CJO35_RS14505	COG1388	LysM domain
CJO35_RS14510	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CJO35_RS14515	COG0157	Belongs to the NadC ModD family
CJO35_RS14520	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CJO35_RS14525	COG1104	cysteine desulfurase activity
CJO35_RS14530	COG1827	regulation of RNA biosynthetic process
CJO35_RS14535	COG0077	Prephenate dehydratase
CJO35_RS14540	COG4492	Belongs to the UPF0735 family
CJO35_RS14545	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CJO35_RS14550	COG3290	protein histidine kinase activity
CJO35_RS14555	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CJO35_RS14560	COG2868	ribosomal protein
CJO35_RS14565	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CJO35_RS14570	COG1994	Peptidase M50
CJO35_RS14575	COG0739	heme binding
CJO35_RS14580	COG3832	glyoxalase III activity
CJO35_RS14585	COG0640	Transcriptional regulator
CJO35_RS14590	COG2894	cell division
CJO35_RS14595	COG0850	regulation of cytokinetic process
CJO35_RS14600	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CJO35_RS14610	COG1077	Cell shape determining protein MreB Mrl
CJO35_RS14620	COG0424	maF-like protein
CJO35_RS14630	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CJO35_RS14635	COG0285	dihydrofolate synthase activity
CJO35_RS14640	COG0525	valine-tRNA ligase activity
CJO35_RS14650	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CJO35_RS14655	COG1388	LysM domain
CJO35_RS14660	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CJO35_RS14665	COG0113	porphobilinogen synthase activity
CJO35_RS14670	COG1587	Uroporphyrinogen-III synthase
CJO35_RS14675	COG0181	hydroxymethylbilane synthase activity
CJO35_RS14680	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CJO35_RS14685	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CJO35_RS14695	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CJO35_RS14700	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CJO35_RS14705	COG1067	ATP-dependent peptidase activity
CJO35_RS14705	COG0470	DNA polymerase III
CJO35_RS14710	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CJO35_RS14715	COG0544	peptidyl-prolyl cis-trans isomerase activity
CJO35_RS14720	COG0457	Tetratricopeptide repeat
CJO35_RS14720	COG1477	protein flavinylation
CJO35_RS14725	COG0066	3-isopropylmalate dehydratase activity
CJO35_RS14730	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CJO35_RS14735	COG0473	3-isopropylmalate dehydrogenase activity
CJO35_RS14740	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CJO35_RS14745	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CJO35_RS14750	COG0440	acetolactate synthase activity
CJO35_RS14755	COG0028	Belongs to the TPP enzyme family
CJO35_RS14760	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CJO35_RS14770	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CJO35_RS14790	COG5518	Phage portal protein
CJO35_RS14845	COG5444	nuclease activity
CJO35_RS14850	COG0457	Tetratricopeptide repeat
CJO35_RS14870	COG0622	Phosphoesterase
CJO35_RS14875	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CJO35_RS14880	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CJO35_RS14885	COG5401	PFAM Sporulation and spore germination
CJO35_RS14890	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CJO35_RS14895	COG1846	Transcriptional regulator
CJO35_RS14900	COG2197	response regulator
CJO35_RS14905	COG4221	oxidoreductase activity
CJO35_RS14910	COG0824	Thioesterase
CJO35_RS14915	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CJO35_RS14920	COG1053	succinate dehydrogenase
CJO35_RS14925	COG2009	succinate dehydrogenase
CJO35_RS14930	COG1719	4-vinyl reductase, 4VR
CJO35_RS14935	COG0527	aspartate kinase activity
CJO35_RS14940	COG0322	excinuclease ABC activity
CJO35_RS14945	COG3118	belongs to the thioredoxin family
CJO35_RS14950	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CJO35_RS14955	COG2086	electron transfer activity
CJO35_RS14960	COG1024	Enoyl-CoA hydratase
CJO35_RS14965	COG1309	transcriptional regulator
CJO35_RS14970	COG0318	PFAM AMP-dependent synthetase and ligase
CJO35_RS14975	COG3766	membrane
CJO35_RS14980	COG1193	negative regulation of DNA recombination
CJO35_RS14985	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CJO35_RS14985	COG1796	DNA polymerase
CJO35_RS14990	COG1286	toxin biosynthetic process
CJO35_RS14995	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CJO35_RS15000	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CJO35_RS15025	COG1137	ATPase activity
CJO35_RS15040	COG0072	phenylalanine-tRNA ligase activity
CJO35_RS15040	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CJO35_RS15045	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CJO35_RS15050	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CJO35_RS15060	COG1966	Carbon starvation protein
CJO35_RS15075	COG0395	ABC-type sugar transport system, permease component
CJO35_RS15080	COG1175	transmembrane transport
CJO35_RS15085	COG1653	transport
CJO35_RS15090	COG0371	Dehydrogenase
CJO35_RS15095	COG0235	Class ii aldolase
CJO35_RS15100	COG1069	ribulokinase activity
CJO35_RS15105	COG2160	L-arabinose isomerase activity
CJO35_RS15110	COG3507	Belongs to the glycosyl hydrolase 43 family
CJO35_RS15115	COG1363	Peptidase, m42
CJO35_RS15125	COG3326	Membrane
CJO35_RS15130	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CJO35_RS15135	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CJO35_RS15140	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CJO35_RS15145	COG1346	cytolysis
CJO35_RS15155	COG3540	Alkaline phosphatase
CJO35_RS15160	COG3279	Response regulator of the LytR AlgR family
CJO35_RS15165	COG3275	phosphorelay sensor kinase activity
CJO35_RS15175	COG1011	Hydrolase
CJO35_RS15180	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CJO35_RS15190	COG0398	Pfam SNARE associated Golgi protein
CJO35_RS15195	COG1484	DNA-dependent DNA replication
CJO35_RS15200	COG3611	Membrane attachment protein
CJO35_RS15205	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CJO35_RS15220	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CJO35_RS15225	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CJO35_RS15230	COG3866	Pectate lyase
CJO35_RS15235	COG0237	dephospho-CoA kinase activity
CJO35_RS15240	COG1971	Probably functions as a manganese efflux pump
CJO35_RS15245	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CJO35_RS15250	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CJO35_RS15250	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CJO35_RS15255	COG5002	protein histidine kinase activity
CJO35_RS15260	COG0745	RESPONSE REGULATOR receiver
CJO35_RS15265	COG0039	L-malate dehydrogenase activity
CJO35_RS15270	COG0538	isocitrate dehydrogenase activity
CJO35_RS15275	COG0372	Belongs to the citrate synthase family
CJO35_RS15280	COG2707	UPF0756 membrane protein
CJO35_RS15285	COG0628	permease
CJO35_RS15290	COG3030	protein affecting phage T7 exclusion by the F plasmid
CJO35_RS15300	COG0205	6-phosphofructokinase activity
CJO35_RS15305	COG0825	malonyl-CoA metabolic process
CJO35_RS15310	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CJO35_RS15315	COG0281	malic enzyme
CJO35_RS15320	COG0587	DNA-directed DNA polymerase activity
CJO35_RS15340	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CJO35_RS15350	COG4109	DRTGG domain
CJO35_RS15355	COG1695	Transcriptional regulator
CJO35_RS15360	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CJO35_RS15365	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_RS15370	COG0165	Argininosuccinate lyase
CJO35_RS15375	COG0137	argininosuccinate synthase activity
CJO35_RS15380	COG0521	Mo-molybdopterin cofactor biosynthetic process
CJO35_RS15385	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CJO35_RS15390	COG0827	DNA restriction-modification system
CJO35_RS15395	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CJO35_RS15400	COG3874	Sporulation protein YtfJ
CJO35_RS15410	COG1714	RDD family
CJO35_RS15415	COG0616	signal peptide processing
CJO35_RS15420	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CJO35_RS15425	COG1566	PFAM secretion protein HlyD family protein
CJO35_RS15430	COG0477	Major facilitator Superfamily
CJO35_RS15440	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CJO35_RS15450	COG0301	tRNA thio-modification
CJO35_RS15455	COG1104	cysteine desulfurase activity
CJO35_RS15460	COG1114	Component of the transport system for branched-chain amino acids
CJO35_RS15465	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CJO35_RS15470	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CJO35_RS15475	COG1309	transcriptional regulator
CJO35_RS15480	COG1956	GAF domain-containing protein
CJO35_RS15495	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CJO35_RS15510	COG3152	Membrane
CJO35_RS15515	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CJO35_RS15520	COG1522	sequence-specific DNA binding
CJO35_RS15525	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CJO35_RS15530	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CJO35_RS15535	COG0454	-acetyltransferase
CJO35_RS15540	COG0517	IMP dehydrogenase activity
CJO35_RS15545	COG0123	including yeast histone deacetylase and acetoin utilization protein
CJO35_RS15550	COG1360	Flagellar Motor Protein
CJO35_RS15555	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CJO35_RS15560	COG1609	Transcriptional regulator
CJO35_RS15565	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CJO35_RS15565	COG1605	Chorismate mutase
CJO35_RS15575	COG3118	belongs to the thioredoxin family
CJO35_RS15580	COG4980	gas vesicle protein
CJO35_RS15585	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CJO35_RS15590	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CJO35_RS15595	COG1674	ftsk spoiiie
CJO35_RS15600	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CJO35_RS15605	COG4848	Belongs to the UPF0354 family
CJO35_RS15610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CJO35_RS15620	COG1363	Peptidase, m42
CJO35_RS15625	COG5584	Small secreted protein
CJO35_RS15630	COG0281	malic enzyme
CJO35_RS15635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CJO35_RS15640	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CJO35_RS15650	COG0510	thiamine kinase activity
CJO35_RS15655	COG1523	belongs to the glycosyl hydrolase 13 family
CJO35_RS15660	COG1597	lipid kinase activity
CJO35_RS15670	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CJO35_RS15675	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CJO35_RS15690	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CJO35_RS15695	COG2252	PERMEase
CJO35_RS15700	COG1349	DNA-binding transcription factor activity
CJO35_RS15705	COG1187	pseudouridine synthase activity
CJO35_RS15710	COG2244	polysaccharide biosynthetic process
CJO35_RS15715	COG2081	HI0933 family
CJO35_RS15720	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CJO35_RS15730	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CJO35_RS15745	COG5578	integral membrane protein
CJO35_RS15750	COG0673	inositol 2-dehydrogenase activity
CJO35_RS15755	COG1653	transport
CJO35_RS15760	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CJO35_RS15765	COG4209	transmembrane transport
CJO35_RS15770	COG2207	Transcriptional regulator
CJO35_RS15775	COG1653	transport
CJO35_RS15780	COG0395	ABC-type sugar transport system, permease component
CJO35_RS15785	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CJO35_RS15790	COG1073	alpha beta
CJO35_RS15800	COG0583	DNA-binding transcription factor activity
CJO35_RS15805	COG0346	lactoylglutathione lyase activity
CJO35_RS15810	COG0495	leucyl-tRNA aminoacylation
CJO35_RS15820	COG2814	Major facilitator Superfamily
CJO35_RS15830	COG2433	Pfam Transposase IS66
CJO35_RS15835	COG0577	efflux transmembrane transporter activity
CJO35_RS15840	COG1136	(ABC) transporter
CJO35_RS15850	COG1131	(ABC) transporter
CJO35_RS15855	COG1725	Transcriptional regulator
CJO35_RS15865	COG1242	4 iron, 4 sulfur cluster binding
CJO35_RS15870	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CJO35_RS15875	COG1301	dicarboxylic acid transport
CJO35_RS15885	COG2267	carboxylic ester hydrolase activity
CJO35_RS15890	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CJO35_RS15895	COG0671	phosphoesterase, PA-phosphatase related
CJO35_RS15900	COG0438	transferase activity, transferring glycosyl groups
CJO35_RS15900	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CJO35_RS15905	COG0367	asparagine synthase
CJO35_RS15910	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CJO35_RS15915	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CJO35_RS15930	COG1506	peptidase
CJO35_RS15935	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CJO35_RS15940	COG1116	anion transmembrane transporter activity
CJO35_RS15945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CJO35_RS15950	COG0494	nUDIX hydrolase
CJO35_RS15960	COG4824	toxin secretion phage lysis holin
CJO35_RS15965	COG0783	Belongs to the Dps family
CJO35_RS15980	COG1854	S-ribosylhomocysteine lyase activity
CJO35_RS15985	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CJO35_RS15990	COG0288	reversible hydration of carbon dioxide
CJO35_RS15995	COG0523	cobalamin synthesis protein
CJO35_RS16000	COG0803	Belongs to the bacterial solute-binding protein 9 family
CJO35_RS16005	COG0254	rRNA binding
CJO35_RS16010	COG1271	oxidase subunit
CJO35_RS16015	COG1294	oxidase, subunit
CJO35_RS16030	COG4948	Mandelate Racemase Muconate Lactonizing
CJO35_RS16035	COG0318	PFAM AMP-dependent synthetase and ligase
CJO35_RS16040	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CJO35_RS16045	COG0596	Alpha beta hydrolase
CJO35_RS16050	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CJO35_RS16055	COG1169	isochorismate synthase
CJO35_RS16060	COG1575	Belongs to the MenA family. Type 1 subfamily
CJO35_RS16065	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CJO35_RS16070	COG0058	SHG alpha-glucan phosphorylase activity
CJO35_RS16075	COG0297	glycogen (starch) synthase activity
CJO35_RS16080	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CJO35_RS16085	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CJO35_RS16090	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CJO35_RS16215	COG1609	Transcriptional regulator
CJO35_RS16220	COG3859	Proton-coupled thiamine transporter YuaJ
CJO35_RS16225	COG3764	Sortase (surface protein transpeptidase)
CJO35_RS16240	COG0457	Tetratricopeptide repeat
CJO35_RS16245	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CJO35_RS16250	COG0569	domain protein
CJO35_RS16255	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CJO35_RS16265	COG2318	DinB family
CJO35_RS16275	COG1454	alcohol dehydrogenase
CJO35_RS16280	COG1012	belongs to the aldehyde dehydrogenase family
CJO35_RS16285	COG1510	regulation of RNA biosynthetic process
CJO35_RS16295	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CJO35_RS16300	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CJO35_RS16305	COG2140	Oxalate decarboxylase
CJO35_RS16335	COG1397	ADP-ribosylglycohydrolase
CJO35_RS16370	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
CJO35_RS16380	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CJO35_RS16385	COG0726	polysaccharide deacetylase
CJO35_RS16390	COG1408	metallophosphoesterase
CJO35_RS16395	COG1968	undecaprenyl-diphosphatase activity
CJO35_RS16400	COG0628	permease
CJO35_RS16405	COG0673	inositol 2-dehydrogenase activity
CJO35_RS16410	COG0693	protein deglycase activity
CJO35_RS16415	COG0840	transmembrane signaling receptor activity
CJO35_RS16420	COG0840	transmembrane signaling receptor activity
CJO35_RS16425	COG0840	transmembrane signaling receptor activity
CJO35_RS16435	COG2070	2-Nitropropane dioxygenase
CJO35_RS16440	COG0432	Pfam Uncharacterised protein family UPF0047
CJO35_RS16445	COG0366	Alpha amylase catalytic
CJO35_RS16460	COG5297	Belongs to the glycosyl hydrolase family 6
CJO35_RS16465	COG1253	flavin adenine dinucleotide binding
CJO35_RS16470	COG2738	Putative neutral zinc metallopeptidase
CJO35_RS16480	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CJO35_RS16495	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CJO35_RS16505	COG0166	Belongs to the GPI family
CJO35_RS16510	COG1979	alcohol dehydrogenase
CJO35_RS16515	COG2155	Conserved Protein
CJO35_RS16520	COG1098	S1 RNA binding domain
CJO35_RS16525	COG0436	Aminotransferase
CJO35_RS16530	COG1522	sequence-specific DNA binding
CJO35_RS16535	COG2267	carboxylic ester hydrolase activity
CJO35_RS16550	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CJO35_RS16565	COG5018	Exonuclease
CJO35_RS16570	COG2814	Major facilitator Superfamily
CJO35_RS16575	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CJO35_RS16580	COG3011	Protein conserved in bacteria
CJO35_RS16590	COG3290	protein histidine kinase activity
CJO35_RS16595	COG4565	transcriptional regulatory protein
CJO35_RS16605	COG1183	phosphatidylcholine synthase activity
CJO35_RS16610	COG0586	Pfam SNARE associated Golgi protein
CJO35_RS16615	COG0688	phosphatidylethanolamine metabolic process
CJO35_RS16620	COG3493	citrate carrier protein
CJO35_RS16630	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CJO35_RS16630	COG2111	Na H antiporter
CJO35_RS16635	COG2111	Na H antiporter
CJO35_RS16640	COG1006	Multisubunit Na H antiporter MnhC subunit
CJO35_RS16645	COG0651	ATP synthesis coupled electron transport
CJO35_RS16650	COG1863	multisubunit Na H antiporter MnhE subunit
CJO35_RS16655	COG2212	antiporter activity
CJO35_RS16660	COG1320	monovalent cation:proton antiporter activity
CJO35_RS16665	COG2050	protein possibly involved in aromatic compounds catabolism
CJO35_RS16670	COG2197	response regulator
CJO35_RS16675	COG4585	Histidine kinase
CJO35_RS16685	COG0142	geranyltranstransferase activity
CJO35_RS16705	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CJO35_RS16710	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CJO35_RS16715	COG1335	isochorismatase
CJO35_RS16720	COG5506	Protein of unknown function (DUF1694)
CJO35_RS16735	COG0628	permease
CJO35_RS16740	COG1959	2 iron, 2 sulfur cluster binding
CJO35_RS16745	COG0657	acetylesterase activity
CJO35_RS16755	COG1418	mRNA catabolic process
CJO35_RS16760	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_RS16770	COG1511	domain protein
CJO35_RS16775	COG1674	ftsk spoiiie
CJO35_RS16775	COG0433	COG0433 Predicted ATPase
CJO35_RS16780	COG4499	WXG100 protein secretion system (Wss), protein YukC
CJO35_RS16785	COG5417	Belongs to the EsaB family
CJO35_RS16790	COG4842	Belongs to the WXG100 family
CJO35_RS16795	COG1115	amino acid carrier protein
CJO35_RS16800	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CJO35_RS16800	COG2508	Transcriptional regulator
CJO35_RS16805	COG0686	Belongs to the AlaDH PNT family
CJO35_RS16815	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CJO35_RS16820	COG1268	BioY protein
CJO35_RS16825	COG2056	Na+-H+ antiporter family
CJO35_RS16830	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CJO35_RS16835	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
CJO35_RS16840	COG3584	3D domain protein
CJO35_RS16850	COG1252	NADH dehydrogenase
CJO35_RS16855	COG0492	ferredoxin-NADP+ reductase activity
CJO35_RS16870	COG0456	acetyltransferase
CJO35_RS16875	COG0316	Belongs to the HesB IscA family
CJO35_RS16880	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CJO35_RS16885	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CJO35_RS16890	COG4844	belongs to the
CJO35_RS16895	COG1252	NADH dehydrogenase
CJO35_RS16900	COG5646	InterPro IPR014922
CJO35_RS16910	COG0457	Tetratricopeptide repeat
CJO35_RS16925	COG4837	Protein of unknown function (DUF1462)
CJO35_RS16930	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CJO35_RS16935	COG1506	peptidase
CJO35_RS16935	COG4946	Tricorn protease homolog
CJO35_RS16935	COG0823	Involved in the tonB-independent uptake of proteins
CJO35_RS16940	COG0083	homoserine kinase activity
CJO35_RS16945	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CJO35_RS16950	COG0460	homoserine dehydrogenase
CJO35_RS16960	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CJO35_RS16965	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CJO35_RS16970	COG0647	UMP catabolic process
CJO35_RS16975	COG2445	Protein of unknown function DUF86
CJO35_RS16980	COG4470	Protein conserved in bacteria
CJO35_RS16995	COG0739	heme binding
CJO35_RS17005	COG0733	neurotransmitter:sodium symporter activity
CJO35_RS17015	COG3377	Domain of unknown function (DUF1805)
CJO35_RS17020	COG0737	Belongs to the 5'-nucleotidase family
CJO35_RS17025	COG0730	response to heat
CJO35_RS17030	COG1801	Protein of unknown function DUF72
CJO35_RS17040	COG3226	Transcriptional regulator
CJO35_RS17050	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CJO35_RS17055	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CJO35_RS17060	COG2508	Transcriptional regulator
CJO35_RS17065	COG2814	Major facilitator Superfamily
CJO35_RS17070	COG1288	antiporter activity
CJO35_RS17075	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CJO35_RS17080	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CJO35_RS17085	COG2356	endonuclease I
CJO35_RS17095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CJO35_RS17110	COG0457	Tetratricopeptide repeat
CJO35_RS17115	COG0719	Fe-S assembly protein
CJO35_RS17120	COG0822	iron-sulfur transferase activity
CJO35_RS17125	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CJO35_RS17130	COG0719	Fe-S assembly protein
CJO35_RS17135	COG0396	ATPase activity
CJO35_RS17145	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CJO35_RS17150	COG1464	Belongs to the NlpA lipoprotein family
CJO35_RS17155	COG2011	ABC-type metal ion transport system permease component
CJO35_RS17160	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CJO35_RS17170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CJO35_RS17175	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CJO35_RS17185	COG0509	glycine decarboxylation via glycine cleavage system
CJO35_RS17190	COG1393	Belongs to the ArsC family
CJO35_RS17195	COG1960	acyl-CoA dehydrogenase activity
CJO35_RS17200	COG0183	Belongs to the thiolase family
CJO35_RS17205	COG1024	Enoyl-CoA hydratase
CJO35_RS17205	COG1250	3-hydroxyacyl-CoA dehydrogenase
CJO35_RS17220	COG5577	PFAM Coat F domain
CJO35_RS17235	COG1120	ATPase activity
CJO35_RS17240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CJO35_RS17245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CJO35_RS17250	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CJO35_RS17265	COG1686	Belongs to the peptidase S11 family
CJO35_RS17270	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_RS17275	COG0783	Belongs to the Dps family
CJO35_RS17280	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CJO35_RS17285	COG0745	RESPONSE REGULATOR receiver
CJO35_RS17290	COG2205	protein histidine kinase activity
CJO35_RS17290	COG2770	Histidine kinase
CJO35_RS17300	COG1309	transcriptional regulator
CJO35_RS17305	COG0114	fumarate hydratase activity
CJO35_RS17315	COG0697	spore germination
CJO35_RS17320	COG0814	amino acid
CJO35_RS17335	COG2197	response regulator
CJO35_RS17340	COG4585	Histidine kinase
CJO35_RS17345	COG4758	membrane
CJO35_RS17355	COG1842	Phage shock protein A
CJO35_RS17360	COG4758	membrane
CJO35_RS17365	COG4677	pectinesterase activity
CJO35_RS17370	COG2096	Adenosyltransferase
CJO35_RS17375	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_RS17390	COG1454	alcohol dehydrogenase
CJO35_RS17395	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CJO35_RS17400	COG1120	ATPase activity
CJO35_RS17405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CJO35_RS17410	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CJO35_RS17415	COG1802	Transcriptional regulator
CJO35_RS17420	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_RS17425	COG2258	MOSC domain
CJO35_RS17430	COG0583	DNA-binding transcription factor activity
CJO35_RS17440	COG2721	sulfolactate sulfo-lyase activity
CJO35_RS17445	COG0246	Mannitol dehydrogenase
CJO35_RS17450	COG1609	Transcriptional regulator
CJO35_RS17455	COG2211	Major facilitator Superfamily
CJO35_RS17460	COG1904	glucuronate isomerase
CJO35_RS17465	COG2205	protein histidine kinase activity
CJO35_RS17470	COG0745	RESPONSE REGULATOR receiver
CJO35_RS17475	COG1120	ATPase activity
CJO35_RS17480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CJO35_RS17485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CJO35_RS17490	COG0531	amino acid
CJO35_RS17500	COG1988	membrane-bound metal-dependent
CJO35_RS17505	COG1368	sulfuric ester hydrolase activity
CJO35_RS17510	COG2814	Major facilitator Superfamily
CJO35_RS17515	COG0656	L-ascorbic acid biosynthetic process
CJO35_RS17520	COG1940	carbohydrate kinase activity
CJO35_RS17525	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CJO35_RS17535	COG3973	AAA domain
CJO35_RS17540	COG2860	membrane
CJO35_RS17545	COG0456	acetyltransferase
CJO35_RS17545	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CJO35_RS17550	COG0456	acetyltransferase
CJO35_RS17555	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CJO35_RS17560	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CJO35_RS17565	COG2217	Heavy metal translocating P-type atpase
CJO35_RS17575	COG1175	transmembrane transport
CJO35_RS17580	COG0395	ABC-type sugar transport system, permease component
CJO35_RS17585	COG1501	Belongs to the glycosyl hydrolase 31 family
CJO35_RS17590	COG1472	Belongs to the glycosyl hydrolase 3 family
CJO35_RS17595	COG1121	(ABC) transporter
CJO35_RS17600	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CJO35_RS17605	COG0803	Belongs to the bacterial solute-binding protein 9 family
CJO35_RS17620	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CJO35_RS17620	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CJO35_RS17625	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CJO35_RS17625	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CJO35_RS17625	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CJO35_RS17640	COG2217	Heavy metal translocating P-type atpase
CJO35_RS17645	COG2608	mercury ion transmembrane transporter activity
CJO35_RS17650	COG1937	Protein conserved in bacteria
CJO35_RS17655	COG0693	protein deglycase activity
CJO35_RS17660	COG1349	DNA-binding transcription factor activity
CJO35_RS17665	COG1070	Carbohydrate kinase
CJO35_RS17670	COG4952	isomerase
CJO35_RS17680	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_RS17680	COG3347	Dehydrogenase
CJO35_RS17685	COG2814	Major facilitator Superfamily
CJO35_RS17690	COG2814	Major facilitator Superfamily
CJO35_RS17700	COG2124	cytochrome p450
CJO35_RS17710	COG1846	Transcriptional regulator
CJO35_RS17720	COG0673	inositol 2-dehydrogenase activity
CJO35_RS17725	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CJO35_RS17730	COG1054	Belongs to the UPF0176 family
CJO35_RS17740	COG1191	sigma factor activity
CJO35_RS17750	COG2140	Oxalate decarboxylase
CJO35_RS17785	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CJO35_RS17825	COG5444	nuclease activity
CJO35_RS17875	COG1705	Flagellar rod assembly protein muramidase FlgJ
CJO35_RS17885	COG3953	SLT domain
CJO35_RS17885	COG5280	Phage tail tape measure protein TP901
CJO35_RS17945	COG1802	Transcriptional regulator
CJO35_RS17945	COG4626	Terminase
CJO35_RS18100	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CJO35_RS18105	COG0557	exoribonuclease II activity
CJO35_RS18110	COG1647	Serine aminopeptidase, S33
CJO35_RS18115	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CJO35_RS18120	COG2002	toxin-antitoxin pair type II binding
CJO35_RS18125	COG1476	TRANSCRIPTIONal
CJO35_RS18130	COG1396	sequence-specific DNA binding
CJO35_RS18135	COG1396	sequence-specific DNA binding
CJO35_RS18140	COG1174	glycine betaine transport
CJO35_RS18145	COG1732	Glycine betaine
CJO35_RS18150	COG1174	glycine betaine transport
CJO35_RS18155	COG1125	glycine betaine transport
CJO35_RS18155	COG0517	IMP dehydrogenase activity
CJO35_RS18160	COG1510	regulation of RNA biosynthetic process
CJO35_RS18165	COG2095	MarC family integral membrane protein
CJO35_RS18180	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CJO35_RS18195	COG0693	protein deglycase activity
CJO35_RS18200	COG0148	phosphopyruvate hydratase activity
CJO35_RS18205	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CJO35_RS18210	COG0149	triose-phosphate isomerase activity
CJO35_RS18215	COG0126	phosphoglycerate kinase activity
CJO35_RS18220	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CJO35_RS18225	COG2390	Transcriptional regulator
CJO35_RS18230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CJO35_RS18235	COG1113	amino acid transport
CJO35_RS18255	COG1556	Lactate utilization protein
CJO35_RS18260	COG1139	Iron-sulfur cluster binding protein
CJO35_RS18265	COG0247	lactate metabolic process
CJO35_RS18270	COG2186	Transcriptional regulator
CJO35_RS18275	COG1620	l-lactate permease
CJO35_RS18280	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CJO35_RS18290	COG5039	Polysaccharide pyruvyl transferase
CJO35_RS18295	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CJO35_RS18300	COG0110	maltose O-acetyltransferase activity
CJO35_RS18305	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CJO35_RS18310	COG2244	polysaccharide biosynthetic process
CJO35_RS18315	COG1216	Glycosyl transferase, family 2
CJO35_RS18320	COG5039	Polysaccharide pyruvyl transferase
CJO35_RS18325	COG1216	Glycosyl transferase, family 2
CJO35_RS18335	COG0438	transferase activity, transferring glycosyl groups
CJO35_RS18340	COG1215	transferase activity, transferring glycosyl groups
CJO35_RS18345	COG0438	transferase activity, transferring glycosyl groups
CJO35_RS18350	COG1086	Polysaccharide biosynthesis protein
CJO35_RS18355	COG0489	protein tyrosine kinase activity
CJO35_RS18360	COG3944	biosynthesis protein
CJO35_RS18365	COG1396	sequence-specific DNA binding
CJO35_RS18370	COG2249	NAD(P)H dehydrogenase (quinone) activity
CJO35_RS18375	COG2271	Major facilitator Superfamily
CJO35_RS18385	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CJO35_RS18400	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CJO35_RS18410	COG1733	regulation of RNA biosynthetic process
CJO35_RS18415	COG1902	pentaerythritol trinitrate reductase activity
CJO35_RS18420	COG1621	beta-fructofuranosidase activity
CJO35_RS18425	COG1621	beta-fructofuranosidase activity
CJO35_RS18440	COG0740	serine-type endopeptidase activity
CJO35_RS18445	COG1611	Belongs to the LOG family
CJO35_RS18450	COG1694	Mazg nucleotide pyrophosphohydrolase
CJO35_RS18455	COG1078	dGTPase activity
CJO35_RS18460	COG0659	secondary active sulfate transmembrane transporter activity
CJO35_RS18465	COG0288	reversible hydration of carbon dioxide
CJO35_RS18470	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CJO35_RS18475	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CJO35_RS18480	COG0640	Transcriptional regulator
CJO35_RS18490	COG2732	(Barnase) inhibitor
CJO35_RS18495	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CJO35_RS18500	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CJO35_RS18505	COG1481	regulation of sporulation
CJO35_RS18510	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CJO35_RS18515	COG1660	Displays ATPase and GTPase activities
CJO35_RS18520	COG1051	belongs to the nudix hydrolase family
CJO35_RS18530	COG0492	ferredoxin-NADP+ reductase activity
CJO35_RS18535	COG0457	Tetratricopeptide repeat
CJO35_RS18540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CJO35_RS18545	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CJO35_RS18545	COG0140	phosphoribosyl-ATP diphosphatase activity
CJO35_RS18550	COG0107	imidazoleglycerol-phosphate synthase activity
CJO35_RS18555	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CJO35_RS18560	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CJO35_RS18565	COG0131	Imidazoleglycerol-phosphate dehydratase
CJO35_RS18570	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CJO35_RS18575	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CJO35_RS18580	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CJO35_RS18585	COG4990	cell redox homeostasis
CJO35_RS18590	COG5297	Belongs to the glycosyl hydrolase family 6
CJO35_RS18595	COG0110	maltose O-acetyltransferase activity
CJO35_RS18600	COG0546	phosphoglycolate phosphatase activity
CJO35_RS18605	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CJO35_RS18610	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CJO35_RS18615	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CJO35_RS18620	COG1846	Transcriptional regulator
CJO35_RS18625	COG2814	Major facilitator Superfamily
CJO35_RS18630	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CJO35_RS18635	COG1950	PFAM Membrane protein of
CJO35_RS18640	COG1983	PspC domain protein
CJO35_RS18645	COG3595	metallopeptidase activity
CJO35_RS18670	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CJO35_RS18675	COG0556	nucleotide-excision repair
CJO35_RS18680	COG4897	Protein conserved in bacteria
CJO35_RS18690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CJO35_RS18700	COG0793	Belongs to the peptidase S41A family
CJO35_RS18700	COG3409	Peptidoglycan-binding domain 1 protein
CJO35_RS18705	COG0473	3-isopropylmalate dehydrogenase activity
CJO35_RS18710	COG3883	PFAM NLP P60 protein
CJO35_RS18710	COG0791	NLP P60 protein
CJO35_RS18715	COG2177	Part of the ABC transporter FtsEX involved in
CJO35_RS18720	COG2884	Cell division ATP-binding protein ftsE
CJO35_RS18730	COG2010	Cytochrome c
CJO35_RS18735	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CJO35_RS18745	COG0653	protein targeting
CJO35_RS18750	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CJO35_RS18765	COG1516	flagellar protein fliS
CJO35_RS18770	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CJO35_RS18775	COG1334	flagellar protein FlaG
CJO35_RS18785	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CJO35_RS18790	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CJO35_RS18795	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
CJO35_RS18805	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CJO35_RS18810	COG4786	Flagellar basal body rod
CJO35_RS18810	COG1256	bacterial-type flagellum assembly
CJO35_RS18815	COG3418	PFAM FlgN family protein
CJO35_RS18820	COG2747	anti-sigma28 factor FlgM
CJO35_RS18830	COG1040	competence protein
CJO35_RS18840	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CJO35_RS18845	COG1307	EDD domain protein, DegV family
CJO35_RS18850	COG2197	response regulator
CJO35_RS18855	COG4585	Histidine kinase
CJO35_RS18860	COG1739	Uncharacterized protein family UPF0029
CJO35_RS18865	COG1316	TRANSCRIPTIONal
CJO35_RS18875	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CJO35_RS18880	COG0438	transferase activity, transferring glycosyl groups
CJO35_RS18885	COG1215	transferase activity, transferring glycosyl groups
CJO35_RS18890	COG3206	protein involved in exopolysaccharide biosynthesis
CJO35_RS18895	COG3307	-O-antigen
CJO35_RS18900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CJO35_RS18905	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CJO35_RS18910	COG0438	transferase activity, transferring glycosyl groups
CJO35_RS18910	COG0297	glycogen (starch) synthase activity
CJO35_RS18915	COG2244	polysaccharide biosynthetic process
CJO35_RS18925	COG2247	cell wall binding repeat
CJO35_RS18925	COG0860	N-Acetylmuramoyl-L-alanine amidase
CJO35_RS18930	COG2247	cell wall binding repeat
CJO35_RS18930	COG2385	sporulation resulting in formation of a cellular spore
CJO35_RS18940	COG1316	TRANSCRIPTIONal
CJO35_RS18945	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CJO35_RS18950	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CJO35_RS18955	COG1134	teichoic acid transport
CJO35_RS18960	COG1682	transport, permease protein
CJO35_RS18965	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CJO35_RS18965	COG0463	Glycosyl transferase, family 2
CJO35_RS18970	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CJO35_RS18975	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CJO35_RS18980	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CJO35_RS18985	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CJO35_RS18995	COG1482	cell wall glycoprotein biosynthetic process
CJO35_RS19015	COG0800	Aldolase
CJO35_RS19020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CJO35_RS19025	COG1609	Transcriptional regulator
CJO35_RS19030	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CJO35_RS19035	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_RS19040	COG1063	alcohol dehydrogenase
CJO35_RS19045	COG2814	Major facilitator Superfamily
CJO35_RS19050	COG1316	TRANSCRIPTIONal
CJO35_RS19055	COG0561	phosphatase activity
CJO35_RS19060	COG0791	NLP P60 protein
CJO35_RS19070	COG2843	Capsule synthesis protein
CJO35_RS19080	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CJO35_RS19085	COG1609	Transcriptional regulator
CJO35_RS19090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CJO35_RS19095	COG1869	D-ribose catabolic process
CJO35_RS19100	COG1129	ABC transporter
CJO35_RS19105	COG1172	Belongs to the binding-protein-dependent transport system permease family
CJO35_RS19110	COG1879	ABC-type sugar transport system periplasmic component
CJO35_RS19120	COG3527	Alpha-acetolactate decarboxylase
CJO35_RS19125	COG0028	Belongs to the TPP enzyme family
CJO35_RS19130	COG0583	DNA-binding transcription factor activity
CJO35_RS19135	COG0405	Gamma-glutamyltransferase
CJO35_RS19140	COG1522	sequence-specific DNA binding
CJO35_RS19145	COG2059	Chromate
CJO35_RS19150	COG2059	Chromate
CJO35_RS19155	COG4464	protein tyrosine phosphatase activity
CJO35_RS19160	COG3944	biosynthesis protein
CJO35_RS19170	COG4715	Zinc finger, swim domain protein
CJO35_RS19175	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CJO35_RS19180	COG0561	phosphatase activity
CJO35_RS19185	COG1349	DNA-binding transcription factor activity
CJO35_RS19195	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_RS19205	COG3732	PTS system glucitol sorbitol-specific
CJO35_RS19225	COG0629	single-stranded DNA binding
CJO35_RS19240	COG1970	mechanosensitive ion channel activity
CJO35_RS19245	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CJO35_RS19250	COG4786	Flagellar basal body rod
CJO35_RS19255	COG4786	Flagellar basal body rod
CJO35_RS19260	COG1077	Cell shape determining protein MreB Mrl
CJO35_RS19265	COG1609	Transcriptional regulator
CJO35_RS19275	COG1846	Transcriptional regulator
CJO35_RS19280	COG2814	Major facilitator Superfamily
CJO35_RS19285	COG0671	phosphoesterase, PA-phosphatase related
CJO35_RS19290	COG1227	inorganic diphosphatase activity
CJO35_RS19295	COG3546	catalase activity
CJO35_RS19300	COG3361	conserved protein (COG2071)
CJO35_RS19305	COG0517	IMP dehydrogenase activity
CJO35_RS19310	COG0598	Magnesium transport protein CorA
CJO35_RS19315	COG1253	flavin adenine dinucleotide binding
CJO35_RS19320	COG0004	ammonium transporteR
CJO35_RS19325	COG0347	Belongs to the P(II) protein family
CJO35_RS19330	COG0740	serine-type endopeptidase activity
CJO35_RS19340	COG0739	heme binding
CJO35_RS19345	COG1247	-acetyltransferase
CJO35_RS19355	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CJO35_RS19365	COG0477	Major facilitator Superfamily
CJO35_RS19370	COG3251	PFAM MbtH domain protein
CJO35_RS19375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CJO35_RS19380	COG3433	isochorismatase activity
CJO35_RS19380	COG1535	isochorismatase
CJO35_RS19385	COG1021	2,3-dihydroxybenzoate-AMP ligase
CJO35_RS19390	COG1169	isochorismate synthase
CJO35_RS19395	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_RS19400	COG2819	hydrolase of the alpha beta superfamily
CJO35_RS19405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CJO35_RS19410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CJO35_RS19415	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CJO35_RS19420	COG2207	Transcriptional regulator
CJO35_RS19420	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CJO35_RS19430	COG2910	NAD(P)H-binding
CJO35_RS19435	COG1959	2 iron, 2 sulfur cluster binding
CJO35_RS19440	COG1994	Peptidase M50
CJO35_RS19445	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CJO35_RS19450	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CJO35_RS19455	COG2223	nitrite transmembrane transporter activity
CJO35_RS19460	COG0243	molybdopterin cofactor binding
CJO35_RS19465	COG2304	oxidoreductase activity
CJO35_RS19470	COG2304	oxidoreductase activity
CJO35_RS19475	COG2385	sporulation resulting in formation of a cellular spore
CJO35_RS19480	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CJO35_RS19490	COG4836	Membrane
CJO35_RS19495	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CJO35_RS19500	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CJO35_RS19505	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CJO35_RS19510	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CJO35_RS19515	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CJO35_RS19520	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CJO35_RS19525	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CJO35_RS19545	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CJO35_RS19550	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CJO35_RS19555	COG4475	Protein of unknown function (DUF436)
CJO35_RS19560	COG0698	ribose 5-phosphate isomerase
CJO35_RS19565	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CJO35_RS19570	COG1971	Probably functions as a manganese efflux pump
CJO35_RS19575	COG0009	L-threonylcarbamoyladenylate synthase
CJO35_RS19580	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CJO35_RS19590	COG0738	Major facilitator superfamily
CJO35_RS19595	COG0673	inositol 2-dehydrogenase activity
CJO35_RS19600	COG0561	phosphatase activity
CJO35_RS19605	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CJO35_RS19610	COG1609	Transcriptional regulator
CJO35_RS19615	COG2890	protein-(glutamine-N5) methyltransferase activity
CJO35_RS19620	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CJO35_RS19625	COG0346	lactoylglutathione lyase activity
CJO35_RS19630	COG0789	Transcriptional regulator
CJO35_RS19635	COG0679	Auxin Efflux Carrier
CJO35_RS19640	COG0281	malic enzyme
CJO35_RS19645	COG1435	thymidine kinase activity
CJO35_RS19650	COG0254	rRNA binding
CJO35_RS19655	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CJO35_RS19660	COG1494	fructose-1,6-bisphosphatase
CJO35_RS19665	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CJO35_RS19670	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CJO35_RS19675	COG0191	fructose-bisphosphate aldolase activity
CJO35_RS19680	COG2204	response regulator
CJO35_RS19685	COG4821	SIS domain
CJO35_RS19690	COG0504	CTP synthase activity
CJO35_RS19695	COG3343	RNA polymerase activity
CJO35_RS19700	COG1960	acyl-CoA dehydrogenase activity
CJO35_RS19705	COG1960	acyl-CoA dehydrogenase activity
CJO35_RS19710	COG1250	3-hydroxyacyl-CoA dehydrogenase
CJO35_RS19715	COG0183	Belongs to the thiolase family
CJO35_RS19720	COG2181	nitrate reductase activity
CJO35_RS19720	COG0247	lactate metabolic process
CJO35_RS19725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CJO35_RS19735	COG0018	arginyl-trna synthetase
CJO35_RS19740	COG4506	Protein conserved in bacteria
CJO35_RS19745	COG0010	Belongs to the arginase family
CJO35_RS19750	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CJO35_RS19765	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CJO35_RS19775	COG1994	Peptidase M50
CJO35_RS19780	COG1942	4-Oxalocrotonate Tautomerase
CJO35_RS19790	COG3465	dGTPase activity
CJO35_RS19795	COG1078	dGTPase activity
CJO35_RS19800	COG4844	belongs to the
CJO35_RS19825	COG2814	Major facilitator Superfamily
CJO35_RS19850	COG1414	Transcriptional regulator
CJO35_RS19860	COG0280	phosphate acetyltransferase
CJO35_RS19865	COG3253	May function as heme-dependent peroxidase
CJO35_RS19880	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CJO35_RS19900	COG1131	(ABC) transporter
CJO35_RS19915	COG2363	Small membrane protein
CJO35_RS19920	COG2233	PERMEase
CJO35_RS19930	COG1012	belongs to the aldehyde dehydrogenase family
CJO35_RS19935	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CJO35_RS19940	COG1216	Glycosyl transferase, family 2
CJO35_RS19945	COG0351	phosphomethylpyrimidine kinase
CJO35_RS19955	COG1621	beta-fructofuranosidase activity
CJO35_RS19960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CJO35_RS19960	COG1263	PTS System
CJO35_RS19965	COG3711	transcriptional antiterminator
CJO35_RS19975	COG1404	Belongs to the peptidase S8 family
CJO35_RS19985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CJO35_RS19990	COG0778	Nitroreductase
CJO35_RS19995	COG1473	amidohydrolase
CJO35_RS20000	COG0772	Belongs to the SEDS family
CJO35_RS20005	COG0772	Belongs to the SEDS family
CJO35_RS20010	COG3314	Sporulation integral membrane protein YlbJ
CJO35_RS20030	COG0456	acetyltransferase
CJO35_RS20065	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CJO35_RS20075	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CJO35_RS20080	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CJO35_RS20085	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CJO35_RS20105	COG3162	membrane
CJO35_RS20110	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CJO35_RS20115	COG1070	Carbohydrate kinase
CJO35_RS20120	COG2115	Belongs to the xylose isomerase family
CJO35_RS20130	COG0352	thiamine-phosphate diphosphorylase activity
CJO35_RS20135	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CJO35_RS20140	COG0583	DNA-binding transcription factor activity
CJO35_RS20155	COG1380	Effector of murein hydrolase LrgA
CJO35_RS20160	COG1346	cytolysis
CJO35_RS20170	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CJO35_RS20175	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CJO35_RS20180	COG0346	lactoylglutathione lyase activity
CJO35_RS20185	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CJO35_RS20190	COG1442	glycosyl transferase family 8
CJO35_RS20205	COG4585	Histidine kinase
CJO35_RS20210	COG2197	response regulator
CJO35_RS20215	COG2409	Drug exporters of the RND superfamily
CJO35_RS20220	COG5522	Integral membrane protein (intg_mem_TP0381)
CJO35_RS20225	COG2271	Major facilitator Superfamily
CJO35_RS20230	COG4948	Mandelate Racemase Muconate Lactonizing
CJO35_RS20235	COG0800	Aldolase
CJO35_RS20240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CJO35_RS20250	COG2234	aminopeptidase activity
CJO35_RS20255	COG0477	Major facilitator Superfamily
CJO35_RS20265	COG2357	RelA SpoT domain protein
CJO35_RS20280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CJO35_RS20285	COG1696	Membrane protein involved in D-alanine export
CJO35_RS20290	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CJO35_RS20295	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CJO35_RS20300	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CJO35_RS20305	COG2814	Major facilitator Superfamily
CJO35_RS20310	COG1486	melibiose metabolic process
CJO35_RS20315	COG1447	Phosphotransferase system cellobiose-specific component IIA
CJO35_RS20320	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CJO35_RS20325	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CJO35_RS20330	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CJO35_RS20330	COG3711	transcriptional antiterminator
CJO35_RS20335	COG2094	Belongs to the DNA glycosylase MPG family
CJO35_RS20345	COG0372	Belongs to the citrate synthase family
CJO35_RS20350	COG2079	MmgE PrpD family protein
CJO35_RS20355	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CJO35_RS20370	COG1132	(ABC) transporter
CJO35_RS20375	COG2755	lipolytic protein G-D-S-L family
CJO35_RS20390	COG2814	Major facilitator Superfamily
CJO35_RS20395	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CJO35_RS20400	COG1131	(ABC) transporter
CJO35_RS20420	COG1595	DNA-templated transcription, initiation
CJO35_RS20425	COG2814	Major facilitator Superfamily
CJO35_RS20430	COG0753	catalase activity
CJO35_RS20435	COG0753	catalase activity
CJO35_RS20440	COG0735	belongs to the Fur family
CJO35_RS20445	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CJO35_RS20450	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CJO35_RS20455	COG1131	(ABC) transporter
CJO35_RS20470	COG1131	(ABC) transporter
CJO35_RS20525	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CJO35_RS20530	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CJO35_RS20535	COG4988	ABC transporter
CJO35_RS20540	COG1294	oxidase, subunit
CJO35_RS20545	COG1271	oxidase subunit
CJO35_RS20555	COG2116	formate transmembrane transporter activity
CJO35_RS20565	COG0281	malic enzyme
CJO35_RS20570	COG1757	Na H antiporter
CJO35_RS20575	COG1027	Aspartate ammonia-lyase
CJO35_RS20580	COG0252	asparaginase activity
CJO35_RS20585	COG1396	sequence-specific DNA binding
CJO35_RS20590	COG2706	6-phosphogluconolactonase activity
CJO35_RS20595	COG0745	RESPONSE REGULATOR receiver
CJO35_RS20600	COG2205	protein histidine kinase activity
CJO35_RS20610	COG1136	(ABC) transporter
CJO35_RS20615	COG0577	efflux transmembrane transporter activity
CJO35_RS20620	COG5294	Protein conserved in bacteria
CJO35_RS20630	COG0726	polysaccharide deacetylase
CJO35_RS20635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CJO35_RS20640	COG1215	transferase activity, transferring glycosyl groups
CJO35_RS20645	COG3493	citrate carrier protein
CJO35_RS20650	COG0584	glycerophosphoryl diester phosphodiesterase
CJO35_RS20665	COG1368	sulfuric ester hydrolase activity
CJO35_RS20675	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CJO35_RS20690	COG2235	arginine
CJO35_RS20695	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CJO35_RS20705	COG0549	Belongs to the carbamate kinase family
CJO35_RS20720	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CJO35_RS20730	COG1595	DNA-templated transcription, initiation
CJO35_RS20740	COG2195	Cleaves the N-terminal amino acid of tripeptides
CJO35_RS20750	COG1621	beta-fructofuranosidase activity
CJO35_RS20755	COG2223	nitrite transmembrane transporter activity
CJO35_RS20765	COG1609	Transcriptional regulator
CJO35_RS20780	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CJO35_RS20785	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CJO35_RS20790	COG0463	Glycosyl transferase, family 2
CJO35_RS20795	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CJO35_RS20820	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CJO35_RS20825	COG0693	protein deglycase activity
CJO35_RS20825	COG0753	catalase activity
CJO35_RS20835	COG2723	6-phospho-beta-galactosidase activity
CJO35_RS20840	COG2190	(PTS) system
CJO35_RS20840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CJO35_RS20840	COG1263	PTS System
CJO35_RS20850	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CJO35_RS20855	COG1122	ATPase activity
CJO35_RS20860	COG4721	ABC-type cobalt transport system, permease component
CJO35_RS20865	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CJO35_RS20870	COG2224	Isocitrate lyase
CJO35_RS20875	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CJO35_RS20885	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CJO35_RS20890	COG0577	efflux transmembrane transporter activity
CJO35_RS20895	COG1136	(ABC) transporter
CJO35_RS20900	COG2205	protein histidine kinase activity
CJO35_RS20905	COG0745	RESPONSE REGULATOR receiver
CJO35_RS20910	COG2723	6-phospho-beta-galactosidase activity
CJO35_RS20915	COG1263	PTS System
CJO35_RS20915	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CJO35_RS20915	COG2190	(PTS) system
CJO35_RS20925	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CJO35_RS20940	COG3507	Belongs to the glycosyl hydrolase 43 family
CJO35_RS20945	COG0513	Belongs to the DEAD box helicase family
CJO35_RS20975	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CJO35_RS20980	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CJO35_RS20985	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CJO35_RS20990	COG2390	Transcriptional regulator
CJO35_RS21000	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CJO35_RS21005	COG3706	GGDEF domain
CJO35_RS21010	COG5298	Protein conserved in bacteria
CJO35_RS21015	COG1215	transferase activity, transferring glycosyl groups
CJO35_RS21025	COG3977	Valine--pyruvate aminotransferase
CJO35_RS21040	COG1181	Belongs to the D-alanine--D-alanine ligase family
CJO35_RS21050	COG0191	fructose-bisphosphate aldolase activity
CJO35_RS21055	COG1082	Xylose isomerase domain protein TIM barrel
CJO35_RS21060	COG1082	Xylose isomerase domain protein TIM barrel
CJO35_RS21065	COG0673	inositol 2-dehydrogenase activity
CJO35_RS21070	COG2814	Major facilitator Superfamily
CJO35_RS21075	COG1082	Xylose isomerase domain protein TIM barrel
CJO35_RS21080	COG3962	Belongs to the TPP enzyme family
CJO35_RS21085	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CJO35_RS21090	COG3718	enzyme involved in inositol metabolism
CJO35_RS21095	COG1012	belongs to the aldehyde dehydrogenase family
CJO35_RS21100	COG1349	DNA-binding transcription factor activity
CJO35_RS21105	COG0667	Aldo Keto reductase
CJO35_RS21110	COG0584	glycerophosphoryl diester phosphodiesterase
CJO35_RS21115	COG2271	Major facilitator Superfamily
CJO35_RS21120	COG0326	Molecular chaperone. Has ATPase activity
CJO35_RS21125	COG0488	(ABC) transporter
CJO35_RS21130	COG0561	phosphatase activity
CJO35_RS21150	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CJO35_RS21180	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
CJO35_RS21185	COG0577	efflux transmembrane transporter activity
CJO35_RS21190	COG1136	(ABC) transporter
CJO35_RS21195	COG2205	protein histidine kinase activity
CJO35_RS21200	COG0745	RESPONSE REGULATOR receiver
CJO35_RS21210	COG0840	transmembrane signaling receptor activity
CJO35_RS21210	COG5278	phosphoserine phosphatase activity
CJO35_RS21215	COG1115	amino acid carrier protein
CJO35_RS21220	COG0686	Belongs to the AlaDH PNT family
CJO35_RS21225	COG3867	Arabinogalactan endo-beta-1,4-galactanase
CJO35_RS21230	COG1874	Beta-galactosidase
CJO35_RS21235	COG3833	ABC-type maltose transport systems, permease component
CJO35_RS21240	COG1175	transmembrane transport
CJO35_RS21245	COG2182	Extracellular solute-binding protein
CJO35_RS21250	COG1609	Transcriptional regulator
CJO35_RS21260	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CJO35_RS21265	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CJO35_RS21270	COG1940	carbohydrate kinase activity
CJO35_RS21295	COG1012	belongs to the aldehyde dehydrogenase family
CJO35_RS21295	COG1454	alcohol dehydrogenase
CJO35_RS21300	COG0450	alkyl hydroperoxide reductase
CJO35_RS21305	COG3634	alkyl hydroperoxide reductase activity
CJO35_RS21330	COG1131	(ABC) transporter
CJO35_RS21335	COG0842	Transport permease protein
CJO35_RS21340	COG4585	Histidine kinase
CJO35_RS21345	COG2197	response regulator
CJO35_RS21370	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CJO35_RS21385	COG0456	acetyltransferase
CJO35_RS21400	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CJO35_RS21405	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CJO35_RS21410	COG4853	Protein conserved in bacteria
CJO35_RS21415	COG4863	YycH protein
CJO35_RS21420	COG5002	protein histidine kinase activity
CJO35_RS21425	COG0745	RESPONSE REGULATOR receiver
CJO35_RS21450	COG1051	belongs to the nudix hydrolase family
CJO35_RS21455	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CJO35_RS21465	COG0305	Participates in initiation and elongation during chromosome replication
CJO35_RS21480	COG3093	addiction module antidote protein HigA
CJO35_RS21485	COG2807	transmembrane transport
CJO35_RS21490	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CJO35_RS21495	COG0363	glucosamine-6-phosphate deaminase activity
CJO35_RS21500	COG2188	Transcriptional regulator
CJO35_RS21505	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CJO35_RS21510	COG1263	PTS System
CJO35_RS21510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CJO35_RS21515	COG0359	binds to the 23S rRNA
CJO35_RS21520	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CJO35_RS21525	COG4241	membrane
CJO35_RS21535	COG5577	PFAM Coat F domain
CJO35_RS21540	COG0589	response to stress
CJO35_RS21545	COG0659	secondary active sulfate transmembrane transporter activity
CJO35_RS21550	COG2271	Major facilitator Superfamily
CJO35_RS21555	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CJO35_RS21560	COG0629	single-stranded DNA binding
CJO35_RS21565	COG0360	Binds together with S18 to 16S ribosomal RNA
CJO35_RS21570	COG0012	GTP binding
CJO35_RS21580	COG4481	Protein conserved in bacteria
CJO35_RS21585	COG3949	Membrane
CJO35_RS21595	COG1475	DNA binding
CJO35_RS21600	COG1192	Involved in chromosome partitioning
CJO35_RS21605	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CJO35_RS21615	COG1475	DNA binding
CJO35_RS21620	COG0357	Ribosomal RNA small subunit methyltransferase G
CJO35_RS21625	COG0445	tRNA wobble uridine modification
CJO35_RS21630	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CJO35_RS21635	COG1847	R3H domain protein
CJO35_RS21640	COG0706	membrane insertase activity
CJO35_RS21645	COG0594	ribonuclease P activity