locus-tag	class	description
LCF45_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LCF45_RS00010	COG0592	DNA-directed DNA polymerase activity
LCF45_RS00015	COG2501	S4 domain
LCF45_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LCF45_RS00025	COG0187	DNA topoisomerase II activity
LCF45_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LCF45_RS00065	COG0517	IMP dehydrogenase activity
LCF45_RS00065	COG0516	GMP reductase activity
LCF45_RS00070	COG1686	Belongs to the peptidase S11 family
LCF45_RS00075	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LCF45_RS00080	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LCF45_RS00100	COG1428	Deoxynucleoside kinase
LCF45_RS00105	COG1428	Deoxynucleoside kinase
LCF45_RS00110	COG1335	isochorismatase
LCF45_RS00115	COG0590	tRNA wobble adenosine to inosine editing
LCF45_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LCF45_RS00130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LCF45_RS00135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LCF45_RS00180	COG1982	Orn Lys Arg decarboxylase major
LCF45_RS00185	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LCF45_RS00190	COG0470	DNA polymerase III
LCF45_RS00195	COG1774	PSP1 C-terminal conserved region
LCF45_RS00200	COG4467	Involved in initiation control of chromosome replication
LCF45_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LCF45_RS00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LCF45_RS00220	COG2002	toxin-antitoxin pair type II binding
LCF45_RS00230	COG0084	hydrolase, TatD family'
LCF45_RS00240	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LCF45_RS00250	COG4466	Protein conserved in bacteria
LCF45_RS00260	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LCF45_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LCF45_RS00270	COG0251	oxidation-reduction process
LCF45_RS00275	COG2088	sporulation resulting in formation of a cellular spore
LCF45_RS00280	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LCF45_RS00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LCF45_RS00305	COG2002	toxin-antitoxin pair type II binding
LCF45_RS00310	COG2244	polysaccharide biosynthetic process
LCF45_RS00315	COG3956	TIGRFAM MazG family protein
LCF45_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LCF45_RS00340	COG1098	S1 RNA binding domain
LCF45_RS00355	COG2208	phosphoserine phosphatase activity
LCF45_RS00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LCF45_RS00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LCF45_RS00375	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LCF45_RS00380	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LCF45_RS00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LCF45_RS00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LCF45_RS00395	COG0512	Glutamine amidotransferase of anthranilate synthase
LCF45_RS00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LCF45_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LCF45_RS00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LCF45_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LCF45_RS00420	COG1396	sequence-specific DNA binding
LCF45_RS00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LCF45_RS00430	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LCF45_RS00515	COG3880	PFAM UvrB UvrC protein
LCF45_RS00520	COG3869	Catalyzes the specific phosphorylation of arginine residues in
LCF45_RS00525	COG0542	response to heat
LCF45_RS00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LCF45_RS00535	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LCF45_RS00540	COG4956	integral membrane protein (PIN domain superfamily)
LCF45_RS00545	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LCF45_RS00555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LCF45_RS00560	COG1045	serine acetyltransferase
LCF45_RS00565	COG0215	cysteine-tRNA ligase activity
LCF45_RS00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LCF45_RS00580	COG3688	RNA-binding protein containing a PIN domain
LCF45_RS00590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LCF45_RS00595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LCF45_RS00600	COG0250	Participates in transcription elongation, termination and antitermination
LCF45_RS00605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LCF45_RS00610	COG0081	regulation of translation
LCF45_RS00615	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LCF45_RS00620	COG0222	ribosome binding
LCF45_RS00625	COG2813	Specifically methylates the guanine in position
LCF45_RS00630	COG0085	RNA polymerase activity
LCF45_RS00635	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LCF45_RS00640	COG1358	cellular component organization or biogenesis
LCF45_RS00645	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LCF45_RS00655	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LCF45_RS00660	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LCF45_RS00665	COG0051	transcription antitermination factor activity, RNA binding
LCF45_RS00670	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LCF45_RS00675	COG0088	Forms part of the polypeptide exit tunnel
LCF45_RS00680	COG0089	rRNA binding
LCF45_RS00685	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LCF45_RS00690	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LCF45_RS00695	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LCF45_RS00710	COG0255	Belongs to the universal ribosomal protein uL29 family
LCF45_RS00715	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LCF45_RS00725	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LCF45_RS00730	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LCF45_RS00740	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LCF45_RS00750	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LCF45_RS00760	COG1841	ribosomal large subunit assembly
LCF45_RS00765	COG0200	Binds to the 23S rRNA
LCF45_RS00770	COG0201	protein transport
LCF45_RS00775	COG0563	adenylate kinase activity
LCF45_RS00780	COG0024	Methionine aminopeptidase
LCF45_RS00790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LCF45_RS00795	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LCF45_RS00800	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LCF45_RS00825	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LCF45_RS00835	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LCF45_RS00840	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LCF45_RS00850	COG0860	N-Acetylmuramoyl-L-alanine amidase
LCF45_RS00855	COG0489	protein tyrosine kinase activity
LCF45_RS00865	COG2194	sulfuric ester hydrolase activity
LCF45_RS00870	COG0726	polysaccharide deacetylase
LCF45_RS00950	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LCF45_RS00955	COG4856	YbbR-like protein
LCF45_RS00960	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LCF45_RS00985	COG1028	Short-chain dehydrogenase reductase Sdr
LCF45_RS00990	COG2011	ABC-type metal ion transport system permease component
LCF45_RS01000	COG1464	Belongs to the NlpA lipoprotein family
LCF45_RS01005	COG0604	alcohol dehydrogenase
LCF45_RS01015	COG0277	FAD linked oxidase domain protein
LCF45_RS01020	COG2271	Major facilitator Superfamily
LCF45_RS01030	COG2814	Major facilitator Superfamily
LCF45_RS01050	COG0601	transmembrane transport
LCF45_RS01055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LCF45_RS01060	COG0444	Belongs to the ABC transporter superfamily
LCF45_RS01065	COG4608	Belongs to the ABC transporter superfamily
LCF45_RS01070	COG4166	transmembrane transport
LCF45_RS01080	COG2207	Transcriptional regulator
LCF45_RS01095	COG4166	transmembrane transport
LCF45_RS01100	COG4166	transmembrane transport
LCF45_RS01105	COG0656	L-ascorbic acid biosynthetic process
LCF45_RS01110	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LCF45_RS01125	COG4149	molybdate abc transporter
LCF45_RS01130	COG0725	ABC transporter, periplasmic molybdate-binding protein
LCF45_RS01135	COG1910	domain protein
LCF45_RS01150	COG0697	spore germination
LCF45_RS01165	COG0204	Acyl-transferase
LCF45_RS01175	COG1609	Transcriptional regulator
LCF45_RS01185	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LCF45_RS01200	COG5298	Protein conserved in bacteria
LCF45_RS01220	COG0488	(ABC) transporter
LCF45_RS01225	COG4585	Histidine kinase
LCF45_RS01230	COG2197	response regulator
LCF45_RS01235	COG1131	(ABC) transporter
LCF45_RS01240	COG0842	Transport permease protein
LCF45_RS01240	COG1511	domain protein
LCF45_RS01245	COG0842	Transport permease protein
LCF45_RS01255	COG0747	negative chemotaxis
LCF45_RS01265	COG0601	transmembrane transport
LCF45_RS01270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LCF45_RS01275	COG0444	Belongs to the ABC transporter superfamily
LCF45_RS01280	COG4608	Belongs to the ABC transporter superfamily
LCF45_RS01285	COG0561	phosphatase activity
LCF45_RS01315	COG3185	4-Hydroxyphenylpyruvate dioxygenase
LCF45_RS01320	COG0179	Fumarylacetoacetate (FAA) hydrolase
LCF45_RS01330	COG0531	amino acid
LCF45_RS01335	COG2814	Major facilitator Superfamily
LCF45_RS01345	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LCF45_RS01355	COG4294	response to UV
LCF45_RS01360	COG0705	Rhomboid family
LCF45_RS01365	COG0736	holo-[acyl-carrier-protein] synthase activity
LCF45_RS01370	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LCF45_RS01380	COG0864	Transcriptional regulator
LCF45_RS01385	COG2337	Toxic component of a toxin-antitoxin (TA) module
LCF45_RS01390	COG2183	response to ionizing radiation
LCF45_RS01490	COG0802	atpase or kinase
LCF45_RS01495	COG1214	PFAM Peptidase M22, glycoprotease
LCF45_RS01500	COG0456	acetyltransferase
LCF45_RS01510	COG0488	(ABC) transporter
LCF45_RS01515	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LCF45_RS01525	COG1266	CAAX protease self-immunity
LCF45_RS01530	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LCF45_RS01540	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LCF45_RS01540	COG0519	Catalyzes the synthesis of GMP from XMP
LCF45_RS01545	COG2252	PERMEase
LCF45_RS01555	COG5002	protein histidine kinase activity
LCF45_RS01580	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LCF45_RS01610	COG2226	methyltransferase
LCF45_RS01620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LCF45_RS01630	COG1215	transferase activity, transferring glycosyl groups
LCF45_RS01675	COG2205	protein histidine kinase activity
LCF45_RS01680	COG0745	RESPONSE REGULATOR receiver
LCF45_RS01700	COG0697	spore germination
LCF45_RS01730	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LCF45_RS01735	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LCF45_RS01740	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LCF45_RS01745	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LCF45_RS01750	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LCF45_RS01755	COG0047	phosphoribosylformylglycinamidine synthase activity
LCF45_RS01760	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LCF45_RS01765	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LCF45_RS01770	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LCF45_RS01775	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LCF45_RS01780	COG0138	bifunctional purine biosynthesis protein purh
LCF45_RS01785	COG0151	Belongs to the GarS family
LCF45_RS01805	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
LCF45_RS01810	COG0210	DNA helicase
LCF45_RS01815	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LCF45_RS01820	COG4851	CamS sex pheromone cAM373 precursor
LCF45_RS01830	COG1012	belongs to the aldehyde dehydrogenase family
LCF45_RS01835	COG1335	isochorismatase
LCF45_RS01845	COG2011	ABC-type metal ion transport system permease component
LCF45_RS01850	COG1464	Belongs to the NlpA lipoprotein family
LCF45_RS01865	COG0003	Pfam Anion-transporting ATPase
LCF45_RS01870	COG1846	Transcriptional regulator
LCF45_RS01875	COG4682	membrane
LCF45_RS01885	COG0154	amidase activity
LCF45_RS01890	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LCF45_RS01895	COG1597	lipid kinase activity
LCF45_RS01905	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LCF45_RS01915	COG1012	belongs to the aldehyde dehydrogenase family
LCF45_RS01920	COG2076	Multidrug Resistance protein
LCF45_RS01925	COG2309	aminopeptidase activity
LCF45_RS01940	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LCF45_RS01950	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LCF45_RS01955	COG5002	protein histidine kinase activity
LCF45_RS01960	COG4807	Protein conserved in bacteria
LCF45_RS01985	COG1757	Na H antiporter
LCF45_RS01990	COG1473	amidohydrolase
LCF45_RS02005	COG0450	alkyl hydroperoxide reductase
LCF45_RS02015	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
LCF45_RS02025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LCF45_RS02030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LCF45_RS02035	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LCF45_RS02040	COG0492	ferredoxin-NADP+ reductase activity
LCF45_RS02050	COG0166	Belongs to the GPI family
LCF45_RS02075	COG5002	protein histidine kinase activity
LCF45_RS02095	COG3541	Predicted nucleotidyltransferase
LCF45_RS02100	COG2814	Major facilitator Superfamily
LCF45_RS02105	COG0723	plastoquinol--plastocyanin reductase activity
LCF45_RS02105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LCF45_RS02115	COG0765	amino acid transport
LCF45_RS02120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LCF45_RS02130	COG0840	transmembrane signaling receptor activity
LCF45_RS02130	COG3290	protein histidine kinase activity
LCF45_RS02135	COG0277	FAD linked oxidase domain protein
LCF45_RS02140	COG0366	Alpha amylase catalytic
LCF45_RS02145	COG1263	PTS System
LCF45_RS02145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCF45_RS02145	COG2190	(PTS) system
LCF45_RS02165	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LCF45_RS02170	COG0352	thiamine-phosphate diphosphorylase activity
LCF45_RS02175	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LCF45_RS02190	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LCF45_RS02200	COG1116	anion transmembrane transporter activity
LCF45_RS02205	COG0488	(ABC) transporter
LCF45_RS02250	COG2270	Major facilitator Superfamily
LCF45_RS02280	COG2310	stress, protein
LCF45_RS02285	COG2310	stress, protein
LCF45_RS02290	COG2310	stress, protein
LCF45_RS02295	COG0861	Integral membrane protein TerC family
LCF45_RS02305	COG3853	Toxic anion resistance protein (TelA)
LCF45_RS02315	COG4840	Belongs to the UPF0435 family
LCF45_RS02320	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LCF45_RS02330	COG1295	ribonuclease BN
LCF45_RS02335	COG2217	Heavy metal translocating P-type atpase
LCF45_RS02340	COG0697	spore germination
LCF45_RS02360	COG0586	Pfam SNARE associated Golgi protein
LCF45_RS02375	COG3871	stress protein (general stress protein 26)
LCF45_RS02380	COG0387	Pfam Sodium calcium exchanger
LCF45_RS02390	COG0535	radical SAM domain protein
LCF45_RS02410	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LCF45_RS02430	COG3829	transcription factor binding
LCF45_RS02440	COG0833	amino acid
LCF45_RS02445	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LCF45_RS02465	COG2066	Belongs to the glutaminase family
LCF45_RS02470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCF45_RS02470	COG1263	PTS System
LCF45_RS02475	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LCF45_RS02490	COG1216	Glycosyl transferase, family 2
LCF45_RS02500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LCF45_RS02500	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LCF45_RS02505	COG0463	Glycosyl transferase, family 2
LCF45_RS02520	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LCF45_RS02525	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LCF45_RS02540	COG1228	amidohydrolase
LCF45_RS02545	COG1090	epimerase
LCF45_RS02550	COG2137	regulation of response to DNA damage stimulus
LCF45_RS02575	COG1988	membrane-bound metal-dependent
LCF45_RS02580	COG1194	a g-specific adenine glycosylase
LCF45_RS02600	COG3557	Belongs to the UPF0374 family
LCF45_RS02605	COG1132	(ABC) transporter
LCF45_RS02610	COG4129	membrane
LCF45_RS02615	COG0067	glutamate synthase
LCF45_RS02615	COG0069	glutamate synthase activity
LCF45_RS02615	COG0070	glutamate synthase
LCF45_RS02620	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LCF45_RS02625	COG4555	ABC transporter
LCF45_RS02645	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LCF45_RS02650	COG0735	belongs to the Fur family
LCF45_RS02770	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LCF45_RS02775	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LCF45_RS02795	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LCF45_RS02805	COG2766	serine protein kinase
LCF45_RS02810	COG2718	Belongs to the UPF0229 family
LCF45_RS02825	COG1585	Membrane protein implicated in regulation of membrane protease activity
LCF45_RS02830	COG2268	Band 7 protein
LCF45_RS02840	COG3290	protein histidine kinase activity
LCF45_RS02845	COG4565	transcriptional regulatory protein
LCF45_RS02850	COG2851	Citrate transporter
LCF45_RS02875	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LCF45_RS02880	COG3842	ATPase activity
LCF45_RS02885	COG1175	transmembrane transport
LCF45_RS02890	COG0395	ABC-type sugar transport system, permease component
LCF45_RS02900	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LCF45_RS02905	COG0745	RESPONSE REGULATOR receiver
LCF45_RS02910	COG5002	protein histidine kinase activity
LCF45_RS02920	COG4990	cell redox homeostasis
LCF45_RS02930	COG3290	protein histidine kinase activity
LCF45_RS02935	COG4565	transcriptional regulatory protein
LCF45_RS02940	COG3493	citrate carrier protein
LCF45_RS02945	COG0281	malic enzyme
LCF45_RS02955	COG0697	spore germination
LCF45_RS02960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LCF45_RS02970	COG5002	protein histidine kinase activity
LCF45_RS02975	COG0745	RESPONSE REGULATOR receiver
LCF45_RS02985	COG0456	acetyltransferase
LCF45_RS02990	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LCF45_RS02995	COG3383	formate dehydrogenase (NAD+) activity
LCF45_RS03000	COG2427	Protein of unknown function (DUF1641)
LCF45_RS03015	COG0531	amino acid
LCF45_RS03025	COG0640	Transcriptional regulator
LCF45_RS03030	COG2217	Heavy metal translocating P-type atpase
LCF45_RS03035	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LCF45_RS03050	COG3227	Zinc metalloprotease (Elastase)
LCF45_RS03070	COG2720	vancomycin resistance protein
LCF45_RS03075	COG1316	TRANSCRIPTIONal
LCF45_RS03080	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LCF45_RS03085	COG0346	lactoylglutathione lyase activity
LCF45_RS03090	COG1253	flavin adenine dinucleotide binding
LCF45_RS03095	COG1027	Aspartate ammonia-lyase
LCF45_RS03100	COG1620	l-lactate permease
LCF45_RS03105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LCF45_RS03120	COG3104	oligopeptide transport
LCF45_RS03125	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LCF45_RS03130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LCF45_RS03135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LCF45_RS03150	COG0156	8-amino-7-oxononanoate synthase activity
LCF45_RS03155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LCF45_RS03165	COG4548	von Willebrand factor, type A
LCF45_RS03170	COG0714	Associated with various cellular activities
LCF45_RS03190	COG0531	amino acid
LCF45_RS03195	COG2188	Transcriptional regulator
LCF45_RS03200	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCF45_RS03200	COG1263	PTS System
LCF45_RS03205	COG0366	Alpha amylase catalytic
LCF45_RS03220	COG0697	spore germination
LCF45_RS03225	COG4585	Histidine kinase
LCF45_RS03230	COG2197	response regulator
LCF45_RS03235	COG1404	Belongs to the peptidase S8 family
LCF45_RS03250	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LCF45_RS03255	COG1115	amino acid carrier protein
LCF45_RS03260	COG1126	abc transporter atp-binding protein
LCF45_RS03265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LCF45_RS03270	COG0765	amino acid transport
LCF45_RS03275	COG0765	amino acid transport
LCF45_RS03280	COG0833	amino acid
LCF45_RS03290	COG2378	regulation of single-species biofilm formation
LCF45_RS03295	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LCF45_RS03300	COG5002	protein histidine kinase activity
LCF45_RS03315	COG0659	secondary active sulfate transmembrane transporter activity
LCF45_RS03330	COG2271	Major facilitator Superfamily
LCF45_RS03335	COG1846	Transcriptional regulator
LCF45_RS03340	COG0477	Major facilitator Superfamily
LCF45_RS03345	COG1609	Transcriptional regulator
LCF45_RS03350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LCF45_RS03355	COG1869	D-ribose catabolic process
LCF45_RS03365	COG1172	Belongs to the binding-protein-dependent transport system permease family
LCF45_RS03370	COG1879	ABC-type sugar transport system periplasmic component
LCF45_RS03400	COG1063	alcohol dehydrogenase
LCF45_RS03415	COG3568	Endonuclease Exonuclease Phosphatase
LCF45_RS03445	COG0840	transmembrane signaling receptor activity
LCF45_RS03450	COG1388	LysM domain
LCF45_RS03450	COG3584	3D domain protein
LCF45_RS03455	COG1476	TRANSCRIPTIONal
LCF45_RS03475	COG3104	oligopeptide transport
LCF45_RS03480	COG1114	Component of the transport system for branched-chain amino acids
LCF45_RS03495	COG1113	amino acid transport
LCF45_RS03500	COG2252	PERMEase
LCF45_RS03525	COG0475	glutathione-regulated potassium exporter activity
LCF45_RS03525	COG0569	domain protein
LCF45_RS03535	COG1845	cytochrome c oxidase, subunit III
LCF45_RS03540	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LCF45_RS03550	COG0833	amino acid
LCF45_RS03555	COG4990	cell redox homeostasis
LCF45_RS03570	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LCF45_RS03575	COG0697	spore germination
LCF45_RS03580	COG0531	amino acid
LCF45_RS03595	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
LCF45_RS03600	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
LCF45_RS03610	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LCF45_RS03615	COG0573	inorganic phosphate transmembrane transporter activity
LCF45_RS03620	COG0581	inorganic phosphate transmembrane transporter activity
LCF45_RS03630	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LCF45_RS03750	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
LCF45_RS03765	COG0860	N-Acetylmuramoyl-L-alanine amidase
LCF45_RS03765	COG3103	Sh3 type 3 domain protein
LCF45_RS03765	COG4991	sh3 domain protein
LCF45_RS03770	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LCF45_RS03775	COG1116	anion transmembrane transporter activity
LCF45_RS03780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LCF45_RS03785	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LCF45_RS03790	COG0352	thiamine-phosphate diphosphorylase activity
LCF45_RS03795	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LCF45_RS03800	COG2104	thiamine diphosphate biosynthetic process
LCF45_RS03805	COG2022	thiamine diphosphate biosynthetic process
LCF45_RS03810	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LCF45_RS03815	COG0351	phosphomethylpyrimidine kinase
LCF45_RS03840	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
LCF45_RS03845	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LCF45_RS03850	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
LCF45_RS03855	COG2205	protein histidine kinase activity
LCF45_RS03860	COG2814	Major facilitator Superfamily
LCF45_RS03865	COG1846	Transcriptional regulator
LCF45_RS03885	COG1172	Belongs to the binding-protein-dependent transport system permease family
LCF45_RS03890	COG1129	ABC transporter
LCF45_RS03895	COG1879	ABC-type sugar transport system periplasmic component
LCF45_RS03900	COG2252	PERMEase
LCF45_RS03905	COG1028	Short-chain dehydrogenase reductase Sdr
LCF45_RS03920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LCF45_RS03925	COG1621	beta-fructofuranosidase activity
LCF45_RS03930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCF45_RS03930	COG1263	PTS System
LCF45_RS03935	COG1609	Transcriptional regulator
LCF45_RS03985	COG0778	Nitroreductase
LCF45_RS03990	COG2719	SpoVR family
LCF45_RS04010	COG1937	Protein conserved in bacteria
LCF45_RS04015	COG0425	Belongs to the sulfur carrier protein TusA family
LCF45_RS04015	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LCF45_RS04020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LCF45_RS04020	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LCF45_RS04025	COG0425	Belongs to the sulfur carrier protein TusA family
LCF45_RS04030	COG0425	Belongs to the sulfur carrier protein TusA family
LCF45_RS04030	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LCF45_RS04035	COG2210	Belongs to the sulfur carrier protein TusA family
LCF45_RS04040	COG0730	response to heat
LCF45_RS04050	COG1316	TRANSCRIPTIONal
LCF45_RS04055	COG0604	alcohol dehydrogenase
LCF45_RS04060	COG1283	sodium-dependent phosphate transmembrane transporter activity
LCF45_RS04065	COG0604	alcohol dehydrogenase
LCF45_RS04070	COG2814	Major facilitator Superfamily
LCF45_RS04080	COG3711	transcriptional antiterminator
LCF45_RS04080	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCF45_RS04085	COG1447	Phosphotransferase system cellobiose-specific component IIA
LCF45_RS04090	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LCF45_RS04115	COG3584	3D domain protein
LCF45_RS04115	COG1388	LysM domain
LCF45_RS04120	COG0577	efflux transmembrane transporter activity
LCF45_RS04125	COG1136	(ABC) transporter
LCF45_RS04135	COG5522	Integral membrane protein (intg_mem_TP0381)
LCF45_RS04150	COG1114	Component of the transport system for branched-chain amino acids
LCF45_RS04155	COG3546	catalase activity
LCF45_RS04185	COG0586	Pfam SNARE associated Golgi protein
LCF45_RS04215	COG0531	amino acid
LCF45_RS04220	COG0475	glutathione-regulated potassium exporter activity
LCF45_RS04230	COG1737	Transcriptional regulator
LCF45_RS04235	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LCF45_RS04240	COG1263	PTS System
LCF45_RS04240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCF45_RS04250	COG2259	Doxx family
LCF45_RS04270	COG0697	spore germination
LCF45_RS04275	COG1522	sequence-specific DNA binding
LCF45_RS04285	COG0300	oxidoreductase activity
LCF45_RS04300	COG2076	Multidrug Resistance protein
LCF45_RS04305	COG1309	transcriptional regulator
LCF45_RS04310	COG2814	Major facilitator Superfamily
LCF45_RS04315	COG1733	regulation of RNA biosynthetic process
LCF45_RS04330	COG4533	DNA binding
LCF45_RS04335	COG2211	Major facilitator Superfamily
LCF45_RS04345	COG0693	protein deglycase activity
LCF45_RS04355	COG0531	amino acid
LCF45_RS04360	COG1012	belongs to the aldehyde dehydrogenase family
LCF45_RS04365	COG1132	(ABC) transporter
LCF45_RS04370	COG1132	(ABC) transporter
LCF45_RS04375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LCF45_RS04380	COG0765	amino acid transport
LCF45_RS04385	COG1126	abc transporter atp-binding protein
LCF45_RS04400	COG0189	ligase activity
LCF45_RS04410	COG4399	Belongs to the UPF0754 family
LCF45_RS04415	COG3679	Belongs to the UPF0342 family
LCF45_RS04430	COG0028	Belongs to the TPP enzyme family
LCF45_RS04435	COG3527	Alpha-acetolactate decarboxylase
LCF45_RS04440	COG0463	Glycosyl transferase, family 2
LCF45_RS04445	COG1216	Glycosyl transferase, family 2
LCF45_RS04450	COG2094	Belongs to the DNA glycosylase MPG family
LCF45_RS04455	COG0561	phosphatase activity
LCF45_RS04465	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LCF45_RS04470	COG0318	PFAM AMP-dependent synthetase and ligase
LCF45_RS04480	COG0659	secondary active sulfate transmembrane transporter activity
LCF45_RS04495	COG0653	protein targeting
LCF45_RS04500	COG2244	polysaccharide biosynthetic process
LCF45_RS04510	COG0860	N-Acetylmuramoyl-L-alanine amidase
LCF45_RS04530	COG1696	Membrane protein involved in D-alanine export
LCF45_RS04545	COG1024	Enoyl-CoA hydratase
LCF45_RS04560	COG1363	Peptidase, m42
LCF45_RS04575	COG2318	DinB family
LCF45_RS04600	COG0579	oxidoreductase
LCF45_RS04635	COG0601	transmembrane transport
LCF45_RS04640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LCF45_RS04645	COG0444	Belongs to the ABC transporter superfamily
LCF45_RS04650	COG4608	Belongs to the ABC transporter superfamily
LCF45_RS04740	COG0477	Major facilitator Superfamily
LCF45_RS04745	COG3290	protein histidine kinase activity
LCF45_RS04750	COG4565	transcriptional regulatory protein
LCF45_RS04755	COG3181	Tripartite tricarboxylate transporter family receptor
LCF45_RS04825	COG0732	type I restriction modification DNA specificity domain
LCF45_RS04830	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LCF45_RS04885	COG0305	Participates in initiation and elongation during chromosome replication
LCF45_RS04915	COG0477	Major facilitator Superfamily
LCF45_RS04950	COG3711	transcriptional antiterminator
LCF45_RS04955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCF45_RS04955	COG1263	PTS System
LCF45_RS04955	COG2190	(PTS) system
LCF45_RS04960	COG2723	6-phospho-beta-galactosidase activity
LCF45_RS04965	COG0456	acetyltransferase
LCF45_RS04975	COG1183	phosphatidylcholine synthase activity
LCF45_RS05040	COG2814	Major facilitator Superfamily
LCF45_RS05045	COG0640	Transcriptional regulator
LCF45_RS05065	COG2376	Dihydroxyacetone kinase
LCF45_RS05075	COG2376	Dihydroxyacetone kinase
LCF45_RS05090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LCF45_RS05140	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LCF45_RS05145	COG1278	Cold shock
LCF45_RS05155	COG4932	domain protein
LCF45_RS05155	COG3266	domain, Protein
LCF45_RS05155	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
LCF45_RS05160	COG0737	Belongs to the 5'-nucleotidase family
LCF45_RS05160	COG1525	nuclease
LCF45_RS05160	COG4085	toxin activity
LCF45_RS05195	COG0825	malonyl-CoA metabolic process
LCF45_RS05215	COG3237	CsbD-like
LCF45_RS05235	COG2172	sigma factor antagonist activity
LCF45_RS05240	COG1191	sigma factor activity
LCF45_RS05250	COG2208	phosphoserine phosphatase activity
LCF45_RS05255	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LCF45_RS05260	COG0784	Response regulator, receiver
LCF45_RS05260	COG2205	protein histidine kinase activity
LCF45_RS05260	COG5002	protein histidine kinase activity
LCF45_RS05305	COG2807	transmembrane transport
LCF45_RS05310	COG2186	Transcriptional regulator
LCF45_RS05315	COG4585	Histidine kinase
LCF45_RS05320	COG2197	response regulator
LCF45_RS05350	COG0420	3'-5' exonuclease activity
LCF45_RS05355	COG4717	serine-type aminopeptidase activity
LCF45_RS05360	COG3481	metal-dependent phosphohydrolase, HD sub domain
LCF45_RS05370	COG0346	lactoylglutathione lyase activity
LCF45_RS05385	COG2267	carboxylic ester hydrolase activity
LCF45_RS05410	COG3620	sequence-specific DNA binding
LCF45_RS05415	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LCF45_RS05420	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LCF45_RS05425	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LCF45_RS05430	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LCF45_RS05435	COG1595	DNA-templated transcription, initiation
LCF45_RS05450	COG3973	AAA domain
LCF45_RS05470	COG1846	Transcriptional regulator
LCF45_RS05480	COG0537	adenosine 5'-monophosphoramidase activity
LCF45_RS05485	COG1131	(ABC) transporter
LCF45_RS05490	COG4473	ABC transporter
LCF45_RS05500	COG0247	lactate metabolic process
LCF45_RS05505	COG1139	Iron-sulfur cluster binding protein
LCF45_RS05510	COG1556	Lactate utilization protein
LCF45_RS05530	COG3402	PFAM membrane-flanked domain
LCF45_RS05535	COG3428	Bacterial PH domain
LCF45_RS05565	COG3402	PFAM membrane-flanked domain
LCF45_RS05570	COG3428	Bacterial PH domain
LCF45_RS05575	COG2329	Antibiotic biosynthesis monooxygenase
LCF45_RS05580	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LCF45_RS05585	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LCF45_RS05590	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LCF45_RS05595	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LCF45_RS05615	COG1309	transcriptional regulator
LCF45_RS05620	COG1511	domain protein
LCF45_RS05655	COG2378	regulation of single-species biofilm formation
LCF45_RS05660	COG1609	Transcriptional regulator
LCF45_RS05670	COG1234	tRNA 3'-trailer cleavage
LCF45_RS05675	COG0095	Lipoate-protein ligase
LCF45_RS05685	COG0318	PFAM AMP-dependent synthetase and ligase
LCF45_RS05700	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LCF45_RS05705	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LCF45_RS05710	COG4208	sulfate ABC transporter
LCF45_RS05725	COG1408	metallophosphoesterase
LCF45_RS05730	COG1078	dGTPase activity
LCF45_RS05745	COG1595	DNA-templated transcription, initiation
LCF45_RS05750	COG3708	Transcriptional regulator
LCF45_RS05750	COG2207	Transcriptional regulator
LCF45_RS05755	COG2205	protein histidine kinase activity
LCF45_RS05760	COG0745	RESPONSE REGULATOR receiver
LCF45_RS05775	COG0501	Belongs to the peptidase M48B family
LCF45_RS05780	COG0697	spore germination
LCF45_RS05805	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LCF45_RS05810	COG2224	Isocitrate lyase
LCF45_RS05820	COG1278	Cold shock
LCF45_RS05835	COG4903	ComK protein
LCF45_RS05840	COG0398	Pfam SNARE associated Golgi protein
LCF45_RS05850	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
LCF45_RS05855	COG1074	ATP-dependent DNA helicase activity
LCF45_RS05905	COG0179	Fumarylacetoacetate (FAA) hydrolase
LCF45_RS05930	COG0367	asparagine synthase
LCF45_RS05940	COG0753	catalase activity
LCF45_RS05945	COG0004	ammonium transporteR
LCF45_RS05955	COG1666	GTP binding
LCF45_RS05960	COG2996	Protein conserved in bacteria
LCF45_RS05965	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LCF45_RS05975	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LCF45_RS05990	COG0561	phosphatase activity
LCF45_RS06010	COG2267	carboxylic ester hydrolase activity
LCF45_RS06025	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LCF45_RS06030	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LCF45_RS06035	COG5504	Zn-dependent protease
LCF45_RS06045	COG0180	Tryptophanyl-tRNA synthetase
LCF45_RS06055	COG4166	transmembrane transport
LCF45_RS06060	COG0601	transmembrane transport
LCF45_RS06065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LCF45_RS06070	COG0444	Belongs to the ABC transporter superfamily
LCF45_RS06075	COG4608	Belongs to the ABC transporter superfamily
LCF45_RS06080	COG0534	Mate efflux family protein
LCF45_RS06085	COG4166	transmembrane transport
LCF45_RS06100	COG0861	Integral membrane protein TerC family
LCF45_RS06105	COG4862	establishment of competence for transformation
LCF45_RS06110	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LCF45_RS06120	COG1164	Oligoendopeptidase f
LCF45_RS06135	COG2346	COG2346, Truncated hemoglobins
LCF45_RS06140	COG4116	CYTH
LCF45_RS06150	COG2357	RelA SpoT domain protein
LCF45_RS06160	COG0564	pseudouridine synthase activity
LCF45_RS06170	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LCF45_RS06175	COG0772	Belongs to the SEDS family
LCF45_RS06180	COG1216	Glycosyl transferase, family 2
LCF45_RS06185	COG2226	methyltransferase
LCF45_RS06200	COG0457	Tetratricopeptide repeat
LCF45_RS06200	COG0463	Glycosyl transferase, family 2
LCF45_RS06220	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LCF45_RS06235	COG1091	dTDP-4-dehydrorhamnose reductase activity
LCF45_RS06280	COG2153	protein acetylation
LCF45_RS06285	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LCF45_RS06290	COG2382	esterase
LCF45_RS06315	COG5492	domain, Protein
LCF45_RS06320	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LCF45_RS06330	COG0512	Glutamine amidotransferase of anthranilate synthase
LCF45_RS06330	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LCF45_RS06335	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LCF45_RS06340	COG0134	indole-3-glycerol-phosphate synthase activity
LCF45_RS06345	COG0135	phosphoribosylanthranilate isomerase activity
LCF45_RS06350	COG0133	tryptophan synthase activity
LCF45_RS06355	COG0159	tryptophan synthase activity
LCF45_RS06365	COG1620	l-lactate permease
LCF45_RS06370	COG5634	Uncharacterized conserved protein (DUF2278)
LCF45_RS06415	COG2226	methyltransferase
LCF45_RS06435	COG0508	dehydrogenase complex catalyzes the overall conversion of
LCF45_RS06440	COG0567	Dehydrogenase, E1 component
LCF45_RS06445	COG1476	TRANSCRIPTIONal
LCF45_RS06470	COG4152	abc transporter atp-binding protein
LCF45_RS06475	COG1668	transmembrane transport
LCF45_RS06495	COG1686	Belongs to the peptidase S11 family
LCF45_RS06500	COG0681	Belongs to the peptidase S26 family
LCF45_RS06535	COG1012	belongs to the aldehyde dehydrogenase family
LCF45_RS06545	COG1176	ABC-type spermidine putrescine transport system, permease component I
LCF45_RS06550	COG1177	transmembrane transport
LCF45_RS06555	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LCF45_RS06565	COG2409	Drug exporters of the RND superfamily
LCF45_RS06575	COG0564	pseudouridine synthase activity
LCF45_RS06585	COG2340	Cysteine-rich secretory protein family
LCF45_RS06590	COG0247	lactate metabolic process
LCF45_RS06595	COG0277	FAD linked oxidase domain protein
LCF45_RS06600	COG3835	regulator
LCF45_RS06610	COG0745	RESPONSE REGULATOR receiver
LCF45_RS06615	COG5002	protein histidine kinase activity
LCF45_RS06620	COG2186	Transcriptional regulator
LCF45_RS06625	COG0247	lactate metabolic process
LCF45_RS06630	COG1139	Iron-sulfur cluster binding protein
LCF45_RS06635	COG1556	Lactate utilization protein
LCF45_RS06640	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LCF45_RS06650	COG2116	formate transmembrane transporter activity
LCF45_RS06655	COG0861	Integral membrane protein TerC family
LCF45_RS06660	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LCF45_RS06670	COG2030	dehydratase
LCF45_RS06690	COG1028	Short-chain dehydrogenase reductase Sdr
LCF45_RS06695	COG3243	poly(R)-hydroxyalkanoic acid synthase
LCF45_RS06705	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LCF45_RS06720	COG1840	ABC-type Fe3 transport system, periplasmic component
LCF45_RS06725	COG3842	ATPase activity
LCF45_RS06735	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LCF45_RS06740	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LCF45_RS06750	COG1349	DNA-binding transcription factor activity
LCF45_RS06760	COG0235	Class ii aldolase
LCF45_RS06770	COG2861	carbohydrate metabolic process
LCF45_RS06780	COG3852	Histidine kinase
LCF45_RS06785	COG1846	Transcriptional regulator
LCF45_RS06795	COG2318	DinB family
LCF45_RS06805	COG5002	protein histidine kinase activity
LCF45_RS06810	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LCF45_RS06815	COG0720	synthase
LCF45_RS06825	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LCF45_RS06830	COG4873	Protein conserved in bacteria
LCF45_RS06845	COG0456	acetyltransferase
LCF45_RS06860	COG1780	Probably involved in ribonucleotide reductase function
LCF45_RS06875	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LCF45_RS06880	COG0531	amino acid
LCF45_RS06885	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LCF45_RS06900	COG2204	response regulator
LCF45_RS06905	COG1012	belongs to the aldehyde dehydrogenase family
LCF45_RS06915	COG1725	Transcriptional regulator
LCF45_RS06920	COG1131	(ABC) transporter
LCF45_RS06930	COG1131	(ABC) transporter
LCF45_RS06935	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LCF45_RS06940	COG1266	CAAX protease self-immunity
LCF45_RS06950	COG1522	sequence-specific DNA binding
LCF45_RS06960	COG1335	isochorismatase
LCF45_RS06970	COG1619	proteins homologs of microcin C7 resistance protein MccF
LCF45_RS06975	COG2070	2-Nitropropane dioxygenase
LCF45_RS06980	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LCF45_RS06985	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LCF45_RS06990	COG1696	Membrane protein involved in D-alanine export
LCF45_RS07015	COG0716	FMN binding
LCF45_RS07050	COG0534	Mate efflux family protein
LCF45_RS07055	COG1968	undecaprenyl-diphosphatase activity
LCF45_RS07075	COG1846	Transcriptional regulator
LCF45_RS07085	COG1301	dicarboxylic acid transport
LCF45_RS07090	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LCF45_RS07100	COG3874	Sporulation protein YtfJ
LCF45_RS07120	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LCF45_RS07125	COG0028	Belongs to the TPP enzyme family
LCF45_RS07130	COG0440	acetolactate synthase activity
LCF45_RS07140	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LCF45_RS07150	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LCF45_RS07160	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LCF45_RS07165	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LCF45_RS07175	COG0131	Imidazoleglycerol-phosphate dehydratase
LCF45_RS07180	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LCF45_RS07185	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LCF45_RS07190	COG0107	imidazoleglycerol-phosphate synthase activity
LCF45_RS07200	COG0140	phosphoribosyl-ATP diphosphatase activity
LCF45_RS07205	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LCF45_RS07220	COG1183	phosphatidylcholine synthase activity
LCF45_RS07225	COG1368	sulfuric ester hydrolase activity
LCF45_RS07235	COG0019	diaminopimelate decarboxylase activity
LCF45_RS07245	COG0175	sulfate reduction
LCF45_RS07250	COG2046	Belongs to the sulfate adenylyltransferase family
LCF45_RS07255	COG0529	Catalyzes the synthesis of activated sulfate
LCF45_RS07260	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LCF45_RS07280	COG1648	precorrin-2 dehydrogenase activity
LCF45_RS07285	COG0733	neurotransmitter:sodium symporter activity
LCF45_RS07310	COG1757	Na H antiporter
LCF45_RS07325	COG4758	membrane
LCF45_RS07330	COG4585	Histidine kinase
LCF45_RS07335	COG2197	response regulator
LCF45_RS07345	COG1114	Component of the transport system for branched-chain amino acids
LCF45_RS07355	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LCF45_RS07395	COG0730	response to heat
LCF45_RS07400	COG0306	phosphate transporter
LCF45_RS07405	COG1392	Phosphate transport regulator
LCF45_RS07410	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LCF45_RS07425	COG3852	Histidine kinase
LCF45_RS07430	COG1801	Protein of unknown function DUF72
LCF45_RS07440	COG0582	viral genome integration into host DNA
LCF45_RS07445	COG5002	protein histidine kinase activity
LCF45_RS07460	COG0392	lysyltransferase activity
LCF45_RS07460	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LCF45_RS07475	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LCF45_RS07480	COG1686	Belongs to the peptidase S11 family
LCF45_RS07485	COG2715	membrane protein required for spore maturation
LCF45_RS07490	COG0700	Nucleoside recognition
LCF45_RS07495	COG1187	pseudouridine synthase activity
LCF45_RS07505	COG1333	cytochrome c biogenesis protein
LCF45_RS07510	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LCF45_RS07515	COG0745	RESPONSE REGULATOR receiver
LCF45_RS07520	COG5002	protein histidine kinase activity
LCF45_RS07525	COG2096	Adenosyltransferase
LCF45_RS07530	COG4942	peptidase
LCF45_RS07540	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LCF45_RS07545	COG1141	Ferredoxin
LCF45_RS07550	COG4955	Helix-turn-helix domain
LCF45_RS07555	COG0514	ATP-dependent DNA helicase (RecQ)
LCF45_RS07560	COG1266	CAAX protease self-immunity
LCF45_RS07570	COG1408	metallophosphoesterase
LCF45_RS07585	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LCF45_RS07605	COG0492	ferredoxin-NADP+ reductase activity
LCF45_RS07610	COG0252	asparaginase activity
LCF45_RS07620	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LCF45_RS07630	COG1304	FMN binding
LCF45_RS07660	COG1160	GTP binding
LCF45_RS07665	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LCF45_RS07685	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LCF45_RS07700	COG0142	geranyltranstransferase activity
LCF45_RS07705	COG2226	methyltransferase
LCF45_RS07710	COG0142	geranyltranstransferase activity
LCF45_RS07735	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LCF45_RS07740	COG0457	Tetratricopeptide repeat
LCF45_RS07745	COG5582	Belongs to the UPF0302 family
LCF45_RS07760	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LCF45_RS07775	COG4347	Protein of unknown function (DUF1405)
LCF45_RS07790	COG2738	Putative neutral zinc metallopeptidase
LCF45_RS07800	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LCF45_RS07805	COG1694	Mazg nucleotide pyrophosphohydrolase
LCF45_RS07810	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LCF45_RS07815	COG1803	Methylglyoxal synthase
LCF45_RS07820	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LCF45_RS07825	COG0438	transferase activity, transferring glycosyl groups
LCF45_RS07830	COG0617	tRNA 3'-terminal CCA addition
LCF45_RS07840	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LCF45_RS07845	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LCF45_RS07855	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LCF45_RS07855	COG1199	ATP-dependent helicase activity
LCF45_RS07875	COG3935	DnaD domain protein
LCF45_RS07880	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LCF45_RS07890	COG4499	WXG100 protein secretion system (Wss), protein YukC
LCF45_RS07890	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LCF45_RS07895	COG3331	DNA recombination
LCF45_RS07930	COG4474	Belongs to the UPF0398 family
LCF45_RS07935	COG3599	regulation of cell shape
LCF45_RS07945	COG0116	Belongs to the methyltransferase superfamily
LCF45_RS07955	COG1199	ATP-dependent helicase activity
LCF45_RS07960	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LCF45_RS07970	COG0024	Methionine aminopeptidase
LCF45_RS07980	COG2233	PERMEase
LCF45_RS07985	COG2311	Membrane
LCF45_RS07990	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LCF45_RS08000	COG0456	acetyltransferase
LCF45_RS08010	COG2897	thiosulfate sulfurtransferase activity
LCF45_RS08050	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LCF45_RS08065	COG0454	-acetyltransferase
LCF45_RS08085	COG0328	RNA-DNA hybrid ribonuclease activity
LCF45_RS08120	COG3403	YqcI/YcgG family
LCF45_RS08125	COG1280	lysine exporter protein (LysE YggA)
LCF45_RS08140	COG3162	membrane
LCF45_RS08145	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LCF45_RS08150	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LCF45_RS08160	COG0475	glutathione-regulated potassium exporter activity
LCF45_RS08165	COG0789	Transcriptional regulator
LCF45_RS08165	COG4978	Transcriptional regulator
LCF45_RS08175	COG2323	membrane
LCF45_RS08180	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LCF45_RS08230	COG1923	regulation of RNA biosynthetic process
LCF45_RS08240	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LCF45_RS08245	COG1360	Flagellar Motor Protein
LCF45_RS08250	COG2201	protein-glutamate methylesterase activity
LCF45_RS08255	COG0643	Histidine kinase
LCF45_RS08255	COG2198	Histidine kinase
LCF45_RS08260	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LCF45_RS08260	COG1776	CheC inhibitor of MCP methylation
LCF45_RS08275	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LCF45_RS08295	COG1256	bacterial-type flagellum assembly
LCF45_RS08300	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LCF45_RS08320	COG1815	bacterial-type flagellum-dependent cell motility
LCF45_RS08325	COG1558	bacterial-type flagellum-dependent cell motility
LCF45_RS08335	COG1766	The M ring may be actively involved in energy transduction
LCF45_RS08340	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LCF45_RS08350	COG1157	protein secretion by the type III secretion system
LCF45_RS08370	COG1749	Flagellar hook protein flgE
LCF45_RS08385	COG0835	chemotaxis
LCF45_RS08385	COG0784	Response regulator, receiver
LCF45_RS08405	COG0861	Integral membrane protein TerC family
LCF45_RS08415	COG3383	formate dehydrogenase (NAD+) activity
LCF45_RS08420	COG2427	Protein of unknown function (DUF1641)
LCF45_RS08425	COG5609	conserved protein (DUF2294)
LCF45_RS08430	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LCF45_RS08440	COG2116	formate transmembrane transporter activity
LCF45_RS08445	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LCF45_RS08450	COG0303	'Molybdopterin
LCF45_RS08455	COG0314	molybdopterin synthase activity
LCF45_RS08460	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LCF45_RS08470	COG0489	protein tyrosine kinase activity
LCF45_RS08485	COG0741	lytic transglycosylase activity
LCF45_RS08495	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LCF45_RS08500	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LCF45_RS08500	COG1776	CheC inhibitor of MCP methylation
LCF45_RS08510	COG1338	Plays a role in the flagellum-specific transport system
LCF45_RS08515	COG1987	bacterial-type flagellum assembly
LCF45_RS08525	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LCF45_RS08530	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LCF45_RS08535	COG1419	protein localization to endoplasmic reticulum
LCF45_RS08540	COG4786	Flagellar basal body rod
LCF45_RS08545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LCF45_RS08575	COG0412	Dienelactone hydrolase
LCF45_RS08580	COG2329	Antibiotic biosynthesis monooxygenase
LCF45_RS08595	COG2814	Major facilitator Superfamily
LCF45_RS08605	COG0583	DNA-binding transcription factor activity
LCF45_RS08610	COG3842	ATPase activity
LCF45_RS08660	COG0406	alpha-ribazole phosphatase activity
LCF45_RS08690	COG0367	asparagine synthase
LCF45_RS08720	COG1802	Transcriptional regulator
LCF45_RS08725	COG0697	spore germination
LCF45_RS08740	COG0438	transferase activity, transferring glycosyl groups
LCF45_RS08740	COG1216	Glycosyl transferase, family 2
LCF45_RS08745	COG1757	Na H antiporter
LCF45_RS08755	COG0277	FAD linked oxidase domain protein
LCF45_RS08775	COG0534	Mate efflux family protein
LCF45_RS08780	COG3340	Belongs to the peptidase S51 family
LCF45_RS08800	COG0785	Cytochrome C biogenesis protein
LCF45_RS08805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LCF45_RS08820	COG3048	D-serine ammonia-lyase activity
LCF45_RS08825	COG2733	membrane
LCF45_RS08860	COG1131	(ABC) transporter
LCF45_RS08875	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LCF45_RS08920	COG0528	UMP kinase activity
LCF45_RS08930	COG1027	Aspartate ammonia-lyase
LCF45_RS08935	COG0281	malic enzyme
LCF45_RS08940	COG4191	Histidine kinase
LCF45_RS08945	COG0784	Response regulator, receiver
LCF45_RS08950	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LCF45_RS08960	COG2502	aspartate--ammonia ligase
LCF45_RS08995	COG1051	belongs to the nudix hydrolase family
LCF45_RS09000	COG0860	N-Acetylmuramoyl-L-alanine amidase
LCF45_RS09010	COG2814	Major facilitator Superfamily
LCF45_RS09040	COG0477	Major facilitator Superfamily
LCF45_RS09045	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LCF45_RS09055	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LCF45_RS09060	COG2223	nitrite transmembrane transporter activity
LCF45_RS09065	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LCF45_RS09080	COG2244	polysaccharide biosynthetic process
LCF45_RS09085	COG0733	neurotransmitter:sodium symporter activity
LCF45_RS09095	COG5566	PFAM Mor transcription activator
LCF45_RS09100	COG2323	membrane
LCF45_RS09115	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LCF45_RS09125	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LCF45_RS09130	COG0028	Belongs to the TPP enzyme family
LCF45_RS09145	COG0129	dihydroxy-acid dehydratase activity
LCF45_RS09150	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LCF45_RS09160	COG2843	Capsule synthesis protein
LCF45_RS09175	COG2814	Major facilitator Superfamily
LCF45_RS09180	COG3384	dioxygenase
LCF45_RS09205	COG4166	transmembrane transport
LCF45_RS09210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LCF45_RS09220	COG1914	H( )-stimulated, divalent metal cation uptake system
LCF45_RS09225	COG1054	Belongs to the UPF0176 family
LCF45_RS09235	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LCF45_RS09245	COG0531	amino acid
LCF45_RS09280	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LCF45_RS09295	COG4257	antibiotic catabolic process
LCF45_RS09300	COG2390	Transcriptional regulator
LCF45_RS09310	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LCF45_RS09315	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LCF45_RS09320	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
LCF45_RS09335	COG4846	Membrane protein involved in cytochrome C biogenesis
LCF45_RS09350	COG0583	DNA-binding transcription factor activity
LCF45_RS09375	COG0006	proline dipeptidase activity
LCF45_RS09380	COG2132	Multicopper oxidase
LCF45_RS09390	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LCF45_RS09410	COG1114	Component of the transport system for branched-chain amino acids
LCF45_RS09420	COG2372	response to copper ion
LCF45_RS09420	COG1276	copper resistance
LCF45_RS09425	COG4549	nuclear export factor GLE1
LCF45_RS09435	COG0697	spore germination
LCF45_RS09440	COG0583	DNA-binding transcription factor activity
LCF45_RS09445	COG1959	2 iron, 2 sulfur cluster binding
LCF45_RS09450	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LCF45_RS09455	COG0778	Nitroreductase
LCF45_RS09475	COG0628	permease
LCF45_RS09490	COG1231	oxidoreductase activity
LCF45_RS09495	COG0523	cobalamin synthesis protein
LCF45_RS09505	COG0318	PFAM AMP-dependent synthetase and ligase
LCF45_RS09510	COG2030	dehydratase
LCF45_RS09515	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LCF45_RS09530	COG0411	ABC transporter
LCF45_RS09550	COG0583	DNA-binding transcription factor activity
LCF45_RS09560	COG1942	4-Oxalocrotonate Tautomerase
LCF45_RS09575	COG0346	lactoylglutathione lyase activity
LCF45_RS09585	COG1271	oxidase subunit
LCF45_RS09590	COG1294	oxidase, subunit
LCF45_RS09595	COG4988	ABC transporter
LCF45_RS09600	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LCF45_RS09630	COG1686	Belongs to the peptidase S11 family
LCF45_RS09645	COG0791	NLP P60 protein
LCF45_RS09645	COG1388	LysM domain
LCF45_RS09655	COG1132	(ABC) transporter
LCF45_RS09660	COG0745	RESPONSE REGULATOR receiver
LCF45_RS09665	COG5002	protein histidine kinase activity
LCF45_RS09670	COG0300	oxidoreductase activity
LCF45_RS09675	COG4122	O-methyltransferase activity
LCF45_RS09695	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
LCF45_RS09705	COG0460	homoserine dehydrogenase
LCF45_RS09715	COG0083	homoserine kinase activity
LCF45_RS09730	COG1316	TRANSCRIPTIONal
LCF45_RS09755	COG1285	pathogenesis
LCF45_RS09760	COG1247	-acetyltransferase
LCF45_RS09780	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LCF45_RS09790	COG1082	Xylose isomerase domain protein TIM barrel
LCF45_RS09800	COG2814	Major facilitator Superfamily
LCF45_RS09805	COG1279	arginine transmembrane transporter activity
LCF45_RS09810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LCF45_RS09820	COG1752	Esterase of the alpha-beta hydrolase superfamily
LCF45_RS09850	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LCF45_RS09855	COG0577	efflux transmembrane transporter activity
LCF45_RS09860	COG2002	toxin-antitoxin pair type II binding
LCF45_RS09865	COG1404	Belongs to the peptidase S8 family
LCF45_RS09870	COG0640	Transcriptional regulator
LCF45_RS09920	COG3949	Membrane
LCF45_RS09925	COG0783	Belongs to the Dps family
LCF45_RS09940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LCF45_RS09950	COG1231	oxidoreductase activity
LCF45_RS09955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LCF45_RS09960	COG4989	oxidoreductase activity
LCF45_RS09965	COG0523	cobalamin synthesis protein
LCF45_RS09970	COG0456	acetyltransferase
LCF45_RS09975	COG0803	Belongs to the bacterial solute-binding protein 9 family
LCF45_RS09990	COG2814	Major facilitator Superfamily
LCF45_RS09995	COG1136	(ABC) transporter
LCF45_RS10000	COG0577	efflux transmembrane transporter activity
LCF45_RS10005	COG0745	RESPONSE REGULATOR receiver
LCF45_RS10010	COG2205	protein histidine kinase activity
LCF45_RS10015	COG1902	pentaerythritol trinitrate reductase activity
LCF45_RS10020	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LCF45_RS10030	COG4166	transmembrane transport
LCF45_RS10035	COG0346	lactoylglutathione lyase activity
LCF45_RS10045	COG0406	alpha-ribazole phosphatase activity
LCF45_RS10055	COG5337	Spore coat protein CotH
LCF45_RS10060	COG1051	belongs to the nudix hydrolase family
LCF45_RS10065	COG0586	Pfam SNARE associated Golgi protein
LCF45_RS10070	COG2244	polysaccharide biosynthetic process
LCF45_RS10080	COG0701	Predicted permease
LCF45_RS10085	COG3689	TIGRFAM TIGR03943 family protein
LCF45_RS10090	COG1607	acyl-coa hydrolase
LCF45_RS10100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LCF45_RS10115	COG0702	epimerase
LCF45_RS10120	COG2839	Protein conserved in bacteria
LCF45_RS10125	COG1253	flavin adenine dinucleotide binding
LCF45_RS10140	COG1114	Component of the transport system for branched-chain amino acids
LCF45_RS10145	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LCF45_RS10165	COG0860	N-Acetylmuramoyl-L-alanine amidase
LCF45_RS10175	COG1876	peptidase activity
LCF45_RS10190	COG2211	Major facilitator Superfamily
LCF45_RS10205	COG0860	N-Acetylmuramoyl-L-alanine amidase
LCF45_RS10215	COG0561	phosphatase activity
LCF45_RS10220	COG1846	Transcriptional regulator
LCF45_RS10225	COG2814	Major facilitator Superfamily
LCF45_RS10235	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LCF45_RS10250	COG1819	glycosyl
LCF45_RS10255	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LCF45_RS10260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LCF45_RS10285	COG0456	acetyltransferase
LCF45_RS10320	COG4499	WXG100 protein secretion system (Wss), protein YukC
LCF45_RS10400	COG3874	Sporulation protein YtfJ
LCF45_RS10425	COG2226	methyltransferase
LCF45_RS10455	COG0604	alcohol dehydrogenase
LCF45_RS10460	COG1595	DNA-templated transcription, initiation
LCF45_RS10480	COG0426	domain, Protein
LCF45_RS10480	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LCF45_RS10490	COG0386	Belongs to the glutathione peroxidase family
LCF45_RS10495	COG1305	Transglutaminase-like
LCF45_RS10500	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
LCF45_RS10505	COG0714	Associated with various cellular activities
LCF45_RS10510	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LCF45_RS10515	COG1140	nitrate reductase beta subunit
LCF45_RS10520	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
LCF45_RS10525	COG2181	nitrate reductase activity
LCF45_RS10530	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LCF45_RS10535	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LCF45_RS10540	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LCF45_RS10545	COG0303	'Molybdopterin
LCF45_RS10550	COG0314	molybdopterin synthase activity
LCF45_RS10560	COG2223	nitrite transmembrane transporter activity
LCF45_RS10580	COG1648	precorrin-2 dehydrogenase activity
LCF45_RS10590	COG1587	Uroporphyrinogen-III synthase
LCF45_RS10590	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LCF45_RS10595	COG2146	nitrite reductase [NAD(P)H] activity
LCF45_RS10600	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LCF45_RS10605	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
LCF45_RS10635	COG2359	stage V sporulation protein S
LCF45_RS10675	COG1418	mRNA catabolic process
LCF45_RS10680	COG0488	(ABC) transporter
LCF45_RS10700	COG1413	lyase activity
LCF45_RS10715	COG2521	methyltransferase
LCF45_RS10715	COG2136	Putative SAM-dependent methyltransferase
LCF45_RS10720	COG0018	arginyl-trna synthetase
LCF45_RS10775	COG0017	Asparaginyl-tRNA synthetase
LCF45_RS10780	COG0733	neurotransmitter:sodium symporter activity
LCF45_RS10805	COG2610	gluconate transmembrane transporter activity
LCF45_RS10815	COG1794	racemase activity, acting on amino acids and derivatives
LCF45_RS10825	COG0456	acetyltransferase
LCF45_RS10830	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LCF45_RS10840	COG1131	(ABC) transporter
LCF45_RS10845	COG4473	ABC transporter
LCF45_RS10855	COG0546	phosphoglycolate phosphatase activity
LCF45_RS10870	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LCF45_RS10885	COG0768	penicillin binding
LCF45_RS10895	COG0204	Acyl-transferase
LCF45_RS10900	COG1272	protein, Hemolysin III
LCF45_RS10905	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LCF45_RS10910	COG0805	protein transport
LCF45_RS10925	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LCF45_RS10930	COG1999	signal sequence binding
LCF45_RS10935	COG0071	Belongs to the small heat shock protein (HSP20) family
LCF45_RS10940	COG0367	asparagine synthase
LCF45_RS10955	COG0860	N-Acetylmuramoyl-L-alanine amidase
LCF45_RS10960	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LCF45_RS10965	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LCF45_RS10985	COG1335	isochorismatase
LCF45_RS10995	COG0668	transmembrane transport
LCF45_RS11000	COG4585	Histidine kinase
LCF45_RS11000	COG2203	Gaf domain
LCF45_RS11005	COG2197	response regulator
LCF45_RS11010	COG1737	Transcriptional regulator
LCF45_RS11015	COG1064	alcohol dehydrogenase
LCF45_RS11030	COG1070	Carbohydrate kinase
LCF45_RS11040	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LCF45_RS11060	COG1125	glycine betaine transport
LCF45_RS11060	COG0517	IMP dehydrogenase activity
LCF45_RS11065	COG1174	glycine betaine transport
LCF45_RS11100	COG1253	flavin adenine dinucleotide binding
LCF45_RS11105	COG1012	belongs to the aldehyde dehydrogenase family
LCF45_RS11110	COG5506	Protein of unknown function (DUF1694)
LCF45_RS11125	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LCF45_RS11130	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LCF45_RS11135	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LCF45_RS11140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LCF45_RS11145	COG0456	acetyltransferase
LCF45_RS11150	COG3829	transcription factor binding
LCF45_RS11155	COG1509	lysine 2,3-aminomutase activity
LCF45_RS11165	COG4479	Belongs to the UPF0346 family
LCF45_RS11190	COG4991	sh3 domain protein
LCF45_RS11190	COG0515	serine threonine protein kinase
LCF45_RS11190	COG3064	Membrane
LCF45_RS11200	COG0671	phosphoesterase, PA-phosphatase related
LCF45_RS11205	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LCF45_RS11210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LCF45_RS11260	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LCF45_RS11285	COG1028	Short-chain dehydrogenase reductase Sdr
LCF45_RS11305	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LCF45_RS11305	COG4499	WXG100 protein secretion system (Wss), protein YukC
LCF45_RS11315	COG2814	Major facilitator Superfamily
LCF45_RS11325	COG0372	Belongs to the citrate synthase family
LCF45_RS11330	COG2079	MmgE PrpD family protein
LCF45_RS11335	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LCF45_RS11340	COG1960	acyl-CoA dehydrogenase activity
LCF45_RS11345	COG2084	Dehydrogenase
LCF45_RS11350	COG1012	belongs to the aldehyde dehydrogenase family
LCF45_RS11355	COG1280	lysine exporter protein (LysE YggA)
LCF45_RS11360	COG1024	Enoyl-CoA hydratase
LCF45_RS11375	COG0420	3'-5' exonuclease activity
LCF45_RS11400	COG2223	nitrite transmembrane transporter activity
LCF45_RS11405	COG1028	Short-chain dehydrogenase reductase Sdr
LCF45_RS11410	COG1169	isochorismate synthase
LCF45_RS11415	COG1021	2,3-dihydroxybenzoate-AMP ligase
LCF45_RS11420	COG1535	isochorismatase
LCF45_RS11420	COG3433	isochorismatase activity
LCF45_RS11425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LCF45_RS11430	COG3251	PFAM MbtH domain protein
LCF45_RS11435	COG2814	Major facilitator Superfamily
LCF45_RS11450	COG0776	regulation of translation
LCF45_RS11460	COG2318	DinB family
LCF45_RS11465	COG1115	amino acid carrier protein
LCF45_RS11480	COG2329	Antibiotic biosynthesis monooxygenase
LCF45_RS11495	COG1187	pseudouridine synthase activity
LCF45_RS11500	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LCF45_RS11505	COG3655	Transcriptional regulator
LCF45_RS11515	COG1136	(ABC) transporter
LCF45_RS11525	COG0596	Alpha beta hydrolase
LCF45_RS11540	COG0028	Belongs to the TPP enzyme family
LCF45_RS11550	COG2226	methyltransferase
LCF45_RS11570	COG1253	flavin adenine dinucleotide binding
LCF45_RS11610	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LCF45_RS11630	COG1846	Transcriptional regulator
LCF45_RS11640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LCF45_RS11645	COG1309	transcriptional regulator
LCF45_RS11675	COG1247	-acetyltransferase
LCF45_RS11705	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LCF45_RS11715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LCF45_RS11745	COG0583	DNA-binding transcription factor activity
LCF45_RS11750	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LCF45_RS11765	COG0583	DNA-binding transcription factor activity
LCF45_RS11770	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LCF45_RS11775	COG2258	MOSC domain
LCF45_RS11790	COG1132	(ABC) transporter
LCF45_RS11795	COG1132	(ABC) transporter
LCF45_RS11810	COG0189	ligase activity
LCF45_RS11825	COG4974	Belongs to the 'phage' integrase family
LCF45_RS11835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LCF45_RS11850	COG1396	sequence-specific DNA binding
LCF45_RS11885	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
LCF45_RS11965	COG2755	lipolytic protein G-D-S-L family
LCF45_RS11965	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LCF45_RS11975	COG2169	Transcriptional regulator
LCF45_RS11980	COG0673	inositol 2-dehydrogenase activity
LCF45_RS11985	COG0673	inositol 2-dehydrogenase activity
LCF45_RS12045	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LCF45_RS12050	COG2971	BadF BadG BcrA BcrD
LCF45_RS12060	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LCF45_RS12110	COG1309	transcriptional regulator
LCF45_RS12125	COG1136	(ABC) transporter
LCF45_RS12130	COG0500	methyltransferase
LCF45_RS12130	COG3615	Tellurite resistance protein tehB
LCF45_RS12140	COG0693	protein deglycase activity
LCF45_RS12150	COG0588	phosphoglycerate mutase activity
LCF45_RS12175	COG2195	Cleaves the N-terminal amino acid of tripeptides
LCF45_RS12185	COG0110	maltose O-acetyltransferase activity
LCF45_RS12190	COG1136	(ABC) transporter
LCF45_RS12215	COG1686	Belongs to the peptidase S11 family
LCF45_RS12245	COG0768	penicillin binding
LCF45_RS12250	COG0745	RESPONSE REGULATOR receiver
LCF45_RS12255	COG2205	protein histidine kinase activity
LCF45_RS12260	COG1136	(ABC) transporter
LCF45_RS12265	COG0577	efflux transmembrane transporter activity
LCF45_RS12275	COG1595	DNA-templated transcription, initiation
LCF45_RS12285	COG0768	penicillin binding
LCF45_RS12290	COG0768	penicillin binding
LCF45_RS12325	COG1252	NADH dehydrogenase
LCF45_RS12330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LCF45_RS12330	COG0425	Belongs to the sulfur carrier protein TusA family
LCF45_RS12345	COG0697	spore germination
LCF45_RS12370	COG3397	chitin binding
LCF45_RS12375	COG0823	Involved in the tonB-independent uptake of proteins
LCF45_RS12385	COG1408	metallophosphoesterase
LCF45_RS12395	COG1131	(ABC) transporter
LCF45_RS12405	COG1309	transcriptional regulator
LCF45_RS12415	COG1960	acyl-CoA dehydrogenase activity
LCF45_RS12420	COG0439	Biotin carboxylase
LCF45_RS12425	COG0511	ligase activity, forming carbon-carbon bonds
LCF45_RS12430	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LCF45_RS12435	COG1024	Enoyl-CoA hydratase
LCF45_RS12440	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LCF45_RS12445	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LCF45_RS12505	COG1686	Belongs to the peptidase S11 family
LCF45_RS12530	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LCF45_RS12555	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LCF45_RS12580	COG1028	Short-chain dehydrogenase reductase Sdr
LCF45_RS12585	COG1733	regulation of RNA biosynthetic process
LCF45_RS12610	COG1309	transcriptional regulator
LCF45_RS12640	COG0697	spore germination
LCF45_RS12645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LCF45_RS12685	COG2323	membrane
LCF45_RS12700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LCF45_RS12705	COG0697	spore germination
LCF45_RS12710	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LCF45_RS12715	COG0201	protein transport
LCF45_RS12725	COG0737	Belongs to the 5'-nucleotidase family
LCF45_RS12730	COG3227	Zinc metalloprotease (Elastase)
LCF45_RS12735	COG1523	belongs to the glycosyl hydrolase 13 family
LCF45_RS12750	COG0076	glutamate decarboxylase activity
LCF45_RS12755	COG0657	acetylesterase activity
LCF45_RS12770	COG0577	efflux transmembrane transporter activity
LCF45_RS12775	COG1136	(ABC) transporter
LCF45_RS12790	COG5002	protein histidine kinase activity
LCF45_RS12795	COG0745	RESPONSE REGULATOR receiver
LCF45_RS12800	COG1011	Hydrolase
LCF45_RS12825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LCF45_RS12830	COG1183	phosphatidylcholine synthase activity
LCF45_RS12845	COG1132	(ABC) transporter
LCF45_RS12850	COG3961	Belongs to the TPP enzyme family
LCF45_RS12870	COG0322	excinuclease ABC activity
LCF45_RS12895	COG2318	DinB family
LCF45_RS12910	COG4667	esterase of the alpha-beta hydrolase superfamily
LCF45_RS12935	COG3878	Protein conserved in bacteria
LCF45_RS12960	COG1051	belongs to the nudix hydrolase family
LCF45_RS12965	COG0592	DNA-directed DNA polymerase activity
LCF45_RS12970	COG2816	NAD+ diphosphatase activity
LCF45_RS12980	COG2223	nitrite transmembrane transporter activity
LCF45_RS12990	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LCF45_RS13000	COG0494	nUDIX hydrolase
LCF45_RS13020	COG0697	spore germination
LCF45_RS13025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LCF45_RS13040	COG0584	glycerophosphoryl diester phosphodiesterase
LCF45_RS13055	COG2814	Major facilitator Superfamily
LCF45_RS13095	COG0768	penicillin binding
LCF45_RS13100	COG0671	phosphoesterase, PA-phosphatase related
LCF45_RS13105	COG0604	alcohol dehydrogenase
LCF45_RS13110	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LCF45_RS13120	COG2205	protein histidine kinase activity
LCF45_RS13135	COG1122	ATPase activity
LCF45_RS13140	COG4720	Psort location CytoplasmicMembrane, score
LCF45_RS13145	COG1794	racemase activity, acting on amino acids and derivatives
LCF45_RS13150	COG1819	glycosyl
LCF45_RS13160	COG0768	penicillin binding
LCF45_RS13165	COG5002	protein histidine kinase activity
LCF45_RS13170	COG0561	phosphatase activity
LCF45_RS13215	COG2124	cytochrome p450
LCF45_RS13265	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LCF45_RS13275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LCF45_RS13280	COG0460	homoserine dehydrogenase
LCF45_RS13300	COG0577	efflux transmembrane transporter activity
LCF45_RS13305	COG1136	(ABC) transporter
LCF45_RS13315	COG0488	(ABC) transporter
LCF45_RS13320	COG0667	Aldo Keto reductase
LCF45_RS13325	COG0583	DNA-binding transcription factor activity
LCF45_RS13330	COG2205	protein histidine kinase activity
LCF45_RS13335	COG0745	RESPONSE REGULATOR receiver
LCF45_RS13345	COG3773	Cell wall hydrolase
LCF45_RS13350	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
LCF45_RS13360	COG3386	PFAM SMP-30 Gluconolaconase
LCF45_RS13400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LCF45_RS13415	COG2959	enzyme of heme biosynthesis
LCF45_RS13440	COG3483	tryptophan 2,3-dioxygenase activity
LCF45_RS13445	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
LCF45_RS13450	COG3844	kynureninase activity
LCF45_RS13455	COG1309	transcriptional regulator
LCF45_RS13470	COG3284	Transcriptional regulator
LCF45_RS13485	COG1349	DNA-binding transcription factor activity
LCF45_RS13505	COG1959	2 iron, 2 sulfur cluster binding
LCF45_RS13520	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LCF45_RS13525	COG0508	dehydrogenase complex catalyzes the overall conversion of
LCF45_RS13530	COG0022	dehydrogenase e1 component
LCF45_RS13535	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LCF45_RS13555	COG1028	Short-chain dehydrogenase reductase Sdr
LCF45_RS13560	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LCF45_RS13560	COG0456	acetyltransferase
LCF45_RS13590	COG4176	ABC-type proline glycine betaine transport system permease component
LCF45_RS13595	COG4175	Glycine betaine
LCF45_RS13595	COG0517	IMP dehydrogenase activity
LCF45_RS13620	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LCF45_RS13625	COG2153	protein acetylation
LCF45_RS13630	COG3397	chitin binding
LCF45_RS13640	COG1819	glycosyl
LCF45_RS13655	COG2205	protein histidine kinase activity
LCF45_RS13660	COG2315	Protein conserved in bacteria
LCF45_RS13710	COG3973	AAA domain
LCF45_RS13720	COG2105	PFAM AIG2 family protein
LCF45_RS13725	COG0514	ATP-dependent DNA helicase (RecQ)
LCF45_RS13750	COG4637	Psort location Cytoplasmic, score
LCF45_RS13760	COG1227	inorganic diphosphatase activity
LCF45_RS13765	COG3397	chitin binding
LCF45_RS13770	COG2318	DinB family
LCF45_RS13790	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LCF45_RS13795	COG1115	amino acid carrier protein
LCF45_RS13800	COG1012	belongs to the aldehyde dehydrogenase family
LCF45_RS13805	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LCF45_RS13815	COG3938	Belongs to the proline racemase family
LCF45_RS13820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LCF45_RS13860	COG0586	Pfam SNARE associated Golgi protein
LCF45_RS13875	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LCF45_RS13880	COG4166	transmembrane transport
LCF45_RS13890	COG4948	Mandelate Racemase Muconate Lactonizing
LCF45_RS13910	COG0667	Aldo Keto reductase
LCF45_RS13950	COG2936	dipeptidyl-peptidase activity
LCF45_RS13960	COG0745	RESPONSE REGULATOR receiver
LCF45_RS13980	COG1307	EDD domain protein, DegV family
LCF45_RS14005	COG1335	isochorismatase
LCF45_RS14020	COG2814	Major facilitator Superfamily
LCF45_RS14030	COG1664	Polymer-forming cytoskeletal
LCF45_RS14035	COG0789	Transcriptional regulator
LCF45_RS14040	COG4533	DNA binding
LCF45_RS14045	COG0477	Major facilitator Superfamily
LCF45_RS14045	COG2814	Major facilitator Superfamily
LCF45_RS14065	COG2261	transglycosylase associated protein
LCF45_RS14080	COG2226	methyltransferase
LCF45_RS14115	COG0436	Aminotransferase
LCF45_RS14120	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LCF45_RS14145	COG1131	(ABC) transporter
LCF45_RS14150	COG2188	Transcriptional regulator
LCF45_RS14195	COG0628	permease
LCF45_RS14245	COG2746	aminoglycoside 3-N-acetyltransferase activity
LCF45_RS14255	COG0697	spore germination
LCF45_RS14260	COG2318	DinB family
LCF45_RS14310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCF45_RS14320	COG2814	Major facilitator Superfamily
LCF45_RS14325	COG1368	sulfuric ester hydrolase activity
LCF45_RS14330	COG0488	(ABC) transporter
LCF45_RS14335	COG1033	growth of symbiont in host cell
LCF45_RS14335	COG2409	Drug exporters of the RND superfamily
LCF45_RS14340	COG1309	transcriptional regulator
LCF45_RS14345	COG0494	nUDIX hydrolase
LCF45_RS14360	COG0287	Prephenate dehydrogenase
LCF45_RS14375	COG1605	Chorismate mutase
LCF45_RS14375	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
LCF45_RS14420	COG1388	LysM domain
LCF45_RS14420	COG3584	3D domain protein
LCF45_RS14430	COG0346	lactoylglutathione lyase activity
LCF45_RS14440	COG0431	NADPH-dependent FMN reductase
LCF45_RS14470	COG0579	oxidoreductase
LCF45_RS14475	COG1879	ABC-type sugar transport system periplasmic component
LCF45_RS14485	COG1172	Belongs to the binding-protein-dependent transport system permease family
LCF45_RS14490	COG1129	ABC transporter
LCF45_RS14495	COG2390	Transcriptional regulator
LCF45_RS14515	COG2226	methyltransferase
LCF45_RS14535	COG2329	Antibiotic biosynthesis monooxygenase
LCF45_RS14565	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LCF45_RS14570	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LCF45_RS14575	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LCF45_RS14580	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LCF45_RS14585	COG3239	Fatty acid desaturase
LCF45_RS14610	COG3842	ATPase activity
LCF45_RS14635	COG1175	transmembrane transport
LCF45_RS14640	COG1349	DNA-binding transcription factor activity
LCF45_RS14650	COG3655	Transcriptional regulator
LCF45_RS14665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LCF45_RS14670	COG0346	lactoylglutathione lyase activity
LCF45_RS14700	COG0714	Associated with various cellular activities
LCF45_RS14720	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LCF45_RS14725	COG0753	catalase activity
LCF45_RS14735	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LCF45_RS14755	COG0778	Nitroreductase
LCF45_RS14760	COG1846	Transcriptional regulator
LCF45_RS14795	COG1725	Transcriptional regulator
LCF45_RS14825	COG2207	Transcriptional regulator
LCF45_RS14830	COG0456	acetyltransferase
LCF45_RS14845	COG0697	spore germination
LCF45_RS14850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LCF45_RS14855	COG1671	Belongs to the UPF0178 family
LCF45_RS14875	COG0456	acetyltransferase
LCF45_RS14875	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LCF45_RS14900	COG0730	response to heat
LCF45_RS14910	COG0833	amino acid
LCF45_RS14920	COG4335	DNA alkylation repair
LCF45_RS14950	COG0768	penicillin binding
LCF45_RS14965	COG3104	oligopeptide transport
LCF45_RS14970	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
LCF45_RS14985	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LCF45_RS14990	COG1984	allophanate hydrolase subunit 2
LCF45_RS14995	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LCF45_RS15000	COG1414	Transcriptional regulator
LCF45_RS15015	COG1960	acyl-CoA dehydrogenase activity
LCF45_RS15040	COG0640	Transcriptional regulator
LCF45_RS15050	COG3314	Sporulation integral membrane protein YlbJ
LCF45_RS15070	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
LCF45_RS15075	COG0577	efflux transmembrane transporter activity
LCF45_RS15080	COG0577	efflux transmembrane transporter activity
LCF45_RS15085	COG1136	(ABC) transporter
LCF45_RS15115	COG0574	Belongs to the PEP-utilizing enzyme family
LCF45_RS15115	COG3848	Pyruvate phosphate dikinase
LCF45_RS15125	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LCF45_RS15150	COG5002	protein histidine kinase activity
LCF45_RS15155	COG0745	RESPONSE REGULATOR receiver
LCF45_RS15165	COG1575	Belongs to the MenA family. Type 1 subfamily
LCF45_RS15195	COG0798	PFAM Bile acid sodium symporter
LCF45_RS15200	COG0346	lactoylglutathione lyase activity
LCF45_RS15205	COG0640	Transcriptional regulator
LCF45_RS15235	COG1309	transcriptional regulator
LCF45_RS15240	COG1028	Short-chain dehydrogenase reductase Sdr
LCF45_RS15245	COG1522	sequence-specific DNA binding
LCF45_RS15265	COG0346	lactoylglutathione lyase activity
LCF45_RS15295	COG0745	RESPONSE REGULATOR receiver
LCF45_RS15300	COG3850	Histidine kinase
LCF45_RS15300	COG5002	protein histidine kinase activity
LCF45_RS15330	COG1073	alpha beta
LCF45_RS15340	COG0814	amino acid
LCF45_RS15345	COG1760	l-serine dehydratase
LCF45_RS15350	COG1760	l-serine dehydratase
LCF45_RS15360	COG5002	protein histidine kinase activity
LCF45_RS15365	COG0745	RESPONSE REGULATOR receiver
LCF45_RS15375	COG5002	protein histidine kinase activity
LCF45_RS15390	COG0814	amino acid
LCF45_RS15395	COG0697	spore germination
LCF45_RS15420	COG4977	sequence-specific DNA binding
LCF45_RS15445	COG2197	response regulator
LCF45_RS15455	COG2814	Major facilitator Superfamily
LCF45_RS15470	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LCF45_RS15490	COG1476	TRANSCRIPTIONal
LCF45_RS15500	COG2226	methyltransferase
LCF45_RS15515	COG1696	Membrane protein involved in D-alanine export
LCF45_RS15525	COG1690	Belongs to the RtcB family
LCF45_RS15540	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LCF45_RS15555	COG1136	(ABC) transporter
LCF45_RS15560	COG0577	efflux transmembrane transporter activity
LCF45_RS15580	COG3850	Histidine kinase
LCF45_RS15580	COG5002	protein histidine kinase activity
LCF45_RS15590	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LCF45_RS15605	COG1619	proteins homologs of microcin C7 resistance protein MccF
LCF45_RS15625	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LCF45_RS15660	COG2814	Major facilitator Superfamily
LCF45_RS15710	COG2849	repeat protein
LCF45_RS15715	COG5444	nuclease activity
LCF45_RS15790	COG0477	Major facilitator Superfamily
LCF45_RS15805	COG1846	Transcriptional regulator
LCF45_RS15810	COG2814	Major facilitator Superfamily
LCF45_RS15830	COG0577	efflux transmembrane transporter activity
LCF45_RS15830	COG1136	(ABC) transporter
LCF45_RS15860	COG1329	Transcriptional regulator
LCF45_RS15870	COG0697	spore germination
LCF45_RS15875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LCF45_RS15920	COG5002	protein histidine kinase activity
LCF45_RS15935	COG1136	(ABC) transporter
LCF45_RS15950	COG1131	(ABC) transporter
LCF45_RS16080	COG4187	Peptidase family M20/M25/M40
LCF45_RS16085	COG1414	Transcriptional regulator
LCF45_RS16090	COG0833	amino acid
LCF45_RS16100	COG2031	fatty acid transporter
LCF45_RS16160	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LCF45_RS16165	COG1288	antiporter activity
LCF45_RS16170	COG2356	endonuclease I
LCF45_RS16175	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LCF45_RS16180	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LCF45_RS16210	COG1785	Belongs to the alkaline phosphatase family
LCF45_RS16215	COG0778	Nitroreductase
LCF45_RS16220	COG1733	regulation of RNA biosynthetic process
LCF45_RS16235	COG1028	Short-chain dehydrogenase reductase Sdr
LCF45_RS16245	COG1131	(ABC) transporter
LCF45_RS16275	COG1011	Hydrolase
LCF45_RS16280	COG2365	Tyrosine phosphatase family
LCF45_RS16305	COG0346	lactoylglutathione lyase activity
LCF45_RS16310	COG1940	carbohydrate kinase activity
LCF45_RS16315	COG0738	Major facilitator superfamily
LCF45_RS16320	COG0110	maltose O-acetyltransferase activity
LCF45_RS16335	COG0628	permease
LCF45_RS16340	COG2261	transglycosylase associated protein
LCF45_RS16375	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
LCF45_RS16385	COG1253	flavin adenine dinucleotide binding
LCF45_RS16390	COG0789	Transcriptional regulator
LCF45_RS16395	COG0697	spore germination
LCF45_RS16400	COG1357	PFAM Pentapeptide repeats (8 copies)
LCF45_RS16405	COG3813	Protein conserved in bacteria
LCF45_RS16410	COG2706	6-phosphogluconolactonase activity
LCF45_RS16415	COG1070	Carbohydrate kinase
LCF45_RS16425	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LCF45_RS16430	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LCF45_RS16445	COG0814	amino acid
LCF45_RS16465	COG1393	Belongs to the ArsC family
LCF45_RS16475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LCF45_RS16490	COG0494	nUDIX hydrolase
LCF45_RS16505	COG0384	phenazine biosynthesis protein PhzF
LCF45_RS16515	COG0318	PFAM AMP-dependent synthetase and ligase
LCF45_RS16520	COG2249	NAD(P)H dehydrogenase (quinone) activity
LCF45_RS16525	COG1733	regulation of RNA biosynthetic process
LCF45_RS16540	COG1191	sigma factor activity
LCF45_RS16555	COG1876	peptidase activity
LCF45_RS16585	COG0741	lytic transglycosylase activity
LCF45_RS16610	COG5002	protein histidine kinase activity
LCF45_RS16655	COG0814	amino acid
LCF45_RS16680	COG1151	hydroxylamine reductase activity
LCF45_RS16710	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LCF45_RS16720	COG2072	flavoprotein involved in K transport
LCF45_RS16760	COG0604	alcohol dehydrogenase
LCF45_RS16765	COG1113	amino acid transport
LCF45_RS16775	COG2814	Major facilitator Superfamily
LCF45_RS16785	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LCF45_RS16790	COG1012	belongs to the aldehyde dehydrogenase family
LCF45_RS16800	COG0534	Mate efflux family protein
LCF45_RS16805	COG1012	belongs to the aldehyde dehydrogenase family
LCF45_RS16810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LCF45_RS16825	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LCF45_RS16830	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LCF45_RS16850	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LCF45_RS16855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LCF45_RS16860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LCF45_RS16865	COG3739	integral membrane protein
LCF45_RS16885	COG0583	DNA-binding transcription factor activity
LCF45_RS16910	COG1193	negative regulation of DNA recombination
LCF45_RS16930	COG2162	N-hydroxyarylamine O-acetyltransferase activity
LCF45_RS16935	COG1164	Oligoendopeptidase f
LCF45_RS16940	COG2957	Belongs to the agmatine deiminase family
LCF45_RS16960	COG3781	membrane
LCF45_RS16975	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LCF45_RS17010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LCF45_RS17015	COG0640	Transcriptional regulator
LCF45_RS17020	COG0604	alcohol dehydrogenase
LCF45_RS17025	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LCF45_RS17030	COG0457	Tetratricopeptide repeat
LCF45_RS17040	COG2808	Putative FMN-binding domain
LCF45_RS17045	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LCF45_RS17055	COG0277	FAD linked oxidase domain protein
LCF45_RS17075	COG1285	pathogenesis
LCF45_RS17085	COG2514	catechol 2,3-dioxygenase activity
LCF45_RS17090	COG2720	vancomycin resistance protein
LCF45_RS17115	COG1278	Cold shock
LCF45_RS17125	COG0716	FMN binding
LCF45_RS17135	COG0494	nUDIX hydrolase
LCF45_RS17155	COG1028	Short-chain dehydrogenase reductase Sdr
LCF45_RS17165	COG0165	Argininosuccinate lyase
LCF45_RS17180	COG4145	pantothenate transmembrane transporter activity
LCF45_RS17190	COG1012	belongs to the aldehyde dehydrogenase family
LCF45_RS17195	COG1028	Short-chain dehydrogenase reductase Sdr
LCF45_RS17205	COG1657	PFAM Prenyltransferase squalene oxidase
LCF45_RS17210	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
LCF45_RS17215	COG2962	Rard protein
LCF45_RS17220	COG3326	Membrane
LCF45_RS17225	COG0531	amino acid
LCF45_RS17260	COG2226	methyltransferase
LCF45_RS17265	COG4166	transmembrane transport
LCF45_RS17270	COG4166	transmembrane transport
LCF45_RS17275	COG4166	transmembrane transport
LCF45_RS17280	COG1316	TRANSCRIPTIONal
LCF45_RS17290	COG1595	DNA-templated transcription, initiation
LCF45_RS17300	COG1131	(ABC) transporter
LCF45_RS17320	COG0673	inositol 2-dehydrogenase activity
LCF45_RS17325	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LCF45_RS17330	COG0187	DNA topoisomerase II activity
LCF45_RS17335	COG1832	CoA-binding protein
LCF45_RS17340	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LCF45_RS17345	COG0745	RESPONSE REGULATOR receiver
LCF45_RS17355	COG1328	CTP reductase activity
LCF45_RS17365	COG4841	protein insertion into membrane
LCF45_RS17370	COG0824	Thioesterase
LCF45_RS17395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LCF45_RS17410	COG1132	(ABC) transporter
LCF45_RS17415	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LCF45_RS17445	COG2211	Major facilitator Superfamily
LCF45_RS17455	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LCF45_RS17470	COG0183	Belongs to the thiolase family
LCF45_RS17475	COG0318	PFAM AMP-dependent synthetase and ligase
LCF45_RS17480	COG1268	BioY protein
LCF45_RS17485	COG0318	PFAM AMP-dependent synthetase and ligase
LCF45_RS17535	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LCF45_RS17545	COG5002	protein histidine kinase activity
LCF45_RS17555	COG0400	carboxylic ester hydrolase activity
LCF45_RS17560	COG0346	lactoylglutathione lyase activity
LCF45_RS17565	COG0069	glutamate synthase activity
LCF45_RS17570	COG1902	pentaerythritol trinitrate reductase activity
LCF45_RS17580	COG1329	Transcriptional regulator
LCF45_RS17585	COG0010	Belongs to the arginase family
LCF45_RS17595	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LCF45_RS17600	COG2986	histidine ammonia-lyase
LCF45_RS17610	COG2226	methyltransferase
LCF45_RS17635	COG4846	Membrane protein involved in cytochrome C biogenesis
LCF45_RS17640	COG0785	Cytochrome C biogenesis protein
LCF45_RS17650	COG1473	amidohydrolase
LCF45_RS17655	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LCF45_RS17660	COG1131	(ABC) transporter
LCF45_RS17670	COG0583	DNA-binding transcription factor activity
LCF45_RS17680	COG1346	cytolysis
LCF45_RS17695	COG0730	response to heat
LCF45_RS17705	COG5632	N-Acetylmuramoyl-L-alanine amidase
LCF45_RS17705	COG3409	Peptidoglycan-binding domain 1 protein
LCF45_RS17725	COG1132	(ABC) transporter
LCF45_RS17730	COG1132	(ABC) transporter
LCF45_RS17735	COG3763	UPF0154 protein
LCF45_RS17755	COG3639	organic phosphonate transmembrane transporter activity
LCF45_RS17765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LCF45_RS17770	COG0737	Belongs to the 5'-nucleotidase family
LCF45_RS17780	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LCF45_RS17785	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LCF45_RS17800	COG1695	Transcriptional regulator
LCF45_RS17805	COG1132	(ABC) transporter
LCF45_RS17840	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LCF45_RS17850	COG1181	Belongs to the D-alanine--D-alanine ligase family
LCF45_RS17855	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LCF45_RS17860	COG5434	Belongs to the glycosyl hydrolase 28 family
LCF45_RS17860	COG3420	alginic acid biosynthetic process
LCF45_RS17885	COG0438	transferase activity, transferring glycosyl groups
LCF45_RS17895	COG0463	Glycosyl transferase, family 2
LCF45_RS17895	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LCF45_RS17900	COG0438	transferase activity, transferring glycosyl groups
LCF45_RS17905	COG0438	transferase activity, transferring glycosyl groups
LCF45_RS17910	COG1086	Polysaccharide biosynthesis protein
LCF45_RS17915	COG0489	protein tyrosine kinase activity
LCF45_RS17920	COG3944	biosynthesis protein
LCF45_RS17925	COG0174	glutamine synthetase
LCF45_RS17930	COG0789	Transcriptional regulator
LCF45_RS17935	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
LCF45_RS17940	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LCF45_RS17945	COG2860	membrane
LCF45_RS17955	COG0464	growth
LCF45_RS17975	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LCF45_RS17985	COG3584	3D domain protein
LCF45_RS17985	COG1388	LysM domain
LCF45_RS17990	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCF45_RS17990	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCF45_RS17990	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCF45_RS17995	COG1105	Belongs to the carbohydrate kinase PfkB family
LCF45_RS18000	COG1349	DNA-binding transcription factor activity
LCF45_RS18005	COG1979	alcohol dehydrogenase
LCF45_RS18010	COG2322	membrane
LCF45_RS18020	COG1113	amino acid transport
LCF45_RS18030	COG1473	amidohydrolase
LCF45_RS18035	COG1408	metallophosphoesterase
LCF45_RS18040	COG2116	formate transmembrane transporter activity
LCF45_RS18055	COG2217	Heavy metal translocating P-type atpase
LCF45_RS18060	COG2608	mercury ion transmembrane transporter activity
LCF45_RS18065	COG1937	Protein conserved in bacteria
LCF45_RS18095	COG4566	intracellular signal transduction
LCF45_RS18105	COG2819	hydrolase of the alpha beta superfamily
LCF45_RS18110	COG1120	ATPase activity
LCF45_RS18115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LCF45_RS18120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LCF45_RS18125	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LCF45_RS18130	COG0708	Exodeoxyribonuclease III
LCF45_RS18135	COG2169	Transcriptional regulator
LCF45_RS18140	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LCF45_RS18145	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LCF45_RS18150	COG2706	6-phosphogluconolactonase activity
LCF45_RS18155	COG2195	Cleaves the N-terminal amino acid of tripeptides
LCF45_RS18160	COG2364	Membrane
LCF45_RS18170	COG0346	lactoylglutathione lyase activity
LCF45_RS18175	COG3300	MHYT domain
LCF45_RS18175	COG5001	Diguanylate cyclase
LCF45_RS18215	COG1346	cytolysis
LCF45_RS18225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LCF45_RS18230	COG0596	Alpha beta hydrolase
LCF45_RS18235	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LCF45_RS18245	COG2188	Transcriptional regulator
LCF45_RS18250	COG2723	6-phospho-beta-galactosidase activity
LCF45_RS18255	COG0823	Involved in the tonB-independent uptake of proteins
LCF45_RS18260	COG3773	Cell wall hydrolase
LCF45_RS18270	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LCF45_RS18290	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LCF45_RS18295	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LCF45_RS18305	COG4550	Control of competence regulator ComK, YlbF/YmcA
LCF45_RS18310	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LCF45_RS18315	COG1013	pyruvate-flavodoxin oxidoreductase activity
LCF45_RS18320	COG0674	pyruvate-flavodoxin oxidoreductase activity
LCF45_RS18320	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LCF45_RS18330	COG2359	stage V sporulation protein S
LCF45_RS18335	COG1692	metallophosphoesterase
LCF45_RS18340	COG1418	mRNA catabolic process
LCF45_RS18345	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LCF45_RS18350	COG1058	Belongs to the CinA family
LCF45_RS18350	COG1546	Belongs to the CinA family
LCF45_RS18355	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LCF45_RS18360	COG1426	Protein conserved in bacteria
LCF45_RS18375	COG0300	oxidoreductase activity
LCF45_RS18380	COG0612	Peptidase, M16
LCF45_RS18385	COG0612	Peptidase, M16
LCF45_RS18390	COG1079	Belongs to the binding-protein-dependent transport system permease family
LCF45_RS18395	COG4603	Belongs to the binding-protein-dependent transport system permease family
LCF45_RS18400	COG3845	ABC transporter
LCF45_RS18405	COG1744	ABC transporter substrate-binding protein PnrA-like
LCF45_RS18410	COG2188	Transcriptional regulator
LCF45_RS18420	COG1674	ftsk spoiiie
LCF45_RS18430	COG0740	serine-type endopeptidase activity
LCF45_RS18435	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LCF45_RS18445	COG0527	aspartate kinase activity
LCF45_RS18450	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LCF45_RS18470	COG3546	catalase activity
LCF45_RS18530	COG3170	Tfp pilus assembly protein FimV
LCF45_RS18615	COG0582	viral genome integration into host DNA
LCF45_RS18660	COG0305	Participates in initiation and elongation during chromosome replication
LCF45_RS18695	COG1396	sequence-specific DNA binding
LCF45_RS18710	COG2856	Zn peptidase
LCF45_RS18725	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LCF45_RS18730	COG1873	PFAM PRC-barrel domain
LCF45_RS18735	COG0612	Peptidase, M16
LCF45_RS18740	COG0726	polysaccharide deacetylase
LCF45_RS18745	COG1185	polyribonucleotide nucleotidyltransferase activity
LCF45_RS18755	COG0196	riboflavin kinase activity
LCF45_RS18765	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LCF45_RS18770	COG1550	Protein conserved in bacteria
LCF45_RS18775	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LCF45_RS18780	COG1358	cellular component organization or biogenesis
LCF45_RS18785	COG2740	Nucleic-acid-binding protein implicated in transcription termination
LCF45_RS18790	COG0195	Participates in both transcription termination and antitermination
LCF45_RS18795	COG0779	Required for maturation of 30S ribosomal subunits
LCF45_RS18805	COG0442	prolyl-tRNA aminoacylation
LCF45_RS18810	COG0750	zinc metalloprotease
LCF45_RS18820	COG4589	Belongs to the CDS family
LCF45_RS18830	COG0233	cytoplasmic translational termination
LCF45_RS18835	COG0528	UMP kinase activity
LCF45_RS18840	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LCF45_RS18850	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LCF45_RS18855	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LCF45_RS18860	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LCF45_RS18865	COG4974	Belongs to the 'phage' integrase family
LCF45_RS18870	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LCF45_RS18875	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LCF45_RS18880	COG0758	DNA mediated transformation
LCF45_RS18890	COG0045	succinate-CoA ligase (ADP-forming) activity
LCF45_RS18895	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LCF45_RS18910	COG0335	large ribosomal subunit rRNA binding
LCF45_RS18915	COG0336	Belongs to the RNA methyltransferase TrmD family
LCF45_RS18920	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LCF45_RS18925	COG1837	Belongs to the UPF0109 family
LCF45_RS18935	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LCF45_RS18945	COG0552	protein localization to endoplasmic reticulum
LCF45_RS18950	COG1196	nuclear chromosome segregation
LCF45_RS18955	COG0571	ribonuclease III activity
LCF45_RS18960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LCF45_RS18965	COG1028	Short-chain dehydrogenase reductase Sdr
LCF45_RS18970	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LCF45_RS18975	COG0416	fatty acid biosynthetic process
LCF45_RS18980	COG1349	DNA-binding transcription factor activity
LCF45_RS18980	COG2050	protein possibly involved in aromatic compounds catabolism
LCF45_RS18985	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LCF45_RS18990	COG1461	Dihydroxyacetone kinase
LCF45_RS18995	COG1302	Protein conserved in bacteria
LCF45_RS19010	COG1564	THIamine pyrophosphokinase
LCF45_RS19015	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LCF45_RS19025	COG0515	serine threonine protein kinase
LCF45_RS19025	COG2815	serine threonine protein kinase
LCF45_RS19030	COG0631	protein serine/threonine phosphatase activity
LCF45_RS19035	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LCF45_RS19040	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LCF45_RS19040	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LCF45_RS19045	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LCF45_RS19050	COG0242	peptide deformylase activity
LCF45_RS19055	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LCF45_RS19060	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LCF45_RS19065	COG1758	RNA polymerase activity
LCF45_RS19080	COG1561	YicC-like family, N-terminal region
LCF45_RS19085	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LCF45_RS19100	COG0006	proline dipeptidase activity
LCF45_RS19115	COG3069	C4-dicarboxylate transmembrane transporter activity
LCF45_RS19125	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LCF45_RS19135	COG0167	dihydroorotate dehydrogenase activity
LCF45_RS19140	COG0543	2 iron, 2 sulfur cluster binding
LCF45_RS19145	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LCF45_RS19155	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LCF45_RS19160	COG0540	Belongs to the ATCase OTCase family
LCF45_RS19170	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LCF45_RS19175	COG0564	pseudouridine synthase activity
LCF45_RS19180	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LCF45_RS19190	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LCF45_RS19195	COG3599	regulation of cell shape
LCF45_RS19200	COG2302	S4 RNA-binding domain
LCF45_RS19205	COG0762	integral membrane protein
LCF45_RS19210	COG1799	cell septum assembly
LCF45_RS19215	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LCF45_RS19225	COG1873	PFAM PRC-barrel domain
LCF45_RS19230	COG1191	sigma factor activity
LCF45_RS19235	COG1191	sigma factor activity
LCF45_RS19245	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LCF45_RS19250	COG0849	cell division
LCF45_RS19255	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LCF45_RS19270	COG0772	Belongs to the SEDS family
LCF45_RS19275	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LCF45_RS19280	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LCF45_RS19285	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LCF45_RS19290	COG0768	penicillin binding
LCF45_RS19295	COG0768	penicillin binding
LCF45_RS19305	COG0275	rRNA processing
LCF45_RS19310	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
LCF45_RS19315	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LCF45_RS19320	COG0454	-acetyltransferase
LCF45_RS19330	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LCF45_RS19335	COG1399	metal-binding, possibly nucleic acid-binding protein
LCF45_RS19340	COG1323	Belongs to the UPF0348 family
LCF45_RS19345	COG3480	Lon protease (S16) C-terminal proteolytic domain
LCF45_RS19350	COG1752	Esterase of the alpha-beta hydrolase superfamily
LCF45_RS19355	COG3314	Sporulation integral membrane protein YlbJ
LCF45_RS19365	COG0742	ribosomal rna small subunit methyltransferase
LCF45_RS19375	COG4471	UPF0298 protein
LCF45_RS19380	COG3679	Belongs to the UPF0342 family
LCF45_RS19385	COG0406	alpha-ribazole phosphatase activity
LCF45_RS19400	COG2340	Cysteine-rich secretory protein family
LCF45_RS19410	COG3336	cytochrome c oxidase
LCF45_RS19435	COG0109	protoheme IX farnesyltransferase activity
LCF45_RS19440	COG1612	heme a metabolic process
LCF45_RS19450	COG0772	Belongs to the SEDS family
LCF45_RS19455	COG4838	Belongs to the UPF0358 family
LCF45_RS19460	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LCF45_RS19465	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LCF45_RS19475	COG4896	Protein conserved in bacteria
LCF45_RS19490	COG1217	gtp-binding protein TYPA
LCF45_RS19500	COG0483	inositol monophosphate 1-phosphatase activity
LCF45_RS19510	COG4493	Belongs to the UPF0637 family
LCF45_RS19515	COG4476	Belongs to the UPF0223 family
LCF45_RS19520	COG1982	Orn Lys Arg decarboxylase major
LCF45_RS19565	COG0508	dehydrogenase complex catalyzes the overall conversion of
LCF45_RS19570	COG0022	dehydrogenase e1 component
LCF45_RS19575	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LCF45_RS19590	COG0561	phosphatase activity
LCF45_RS19595	COG5503	Protein of unknown function (DUF1447)
LCF45_RS19600	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LCF45_RS19605	COG0569	domain protein
LCF45_RS19615	COG1473	amidohydrolase
LCF45_RS19620	COG2171	N-acyltransferase activity
LCF45_RS19625	COG0583	DNA-binding transcription factor activity
LCF45_RS19630	COG0517	IMP dehydrogenase activity
LCF45_RS19640	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
LCF45_RS19650	COG4703	Protein of unknown function (DUF1797)
LCF45_RS19665	COG2200	EAL domain
LCF45_RS19670	COG1028	Short-chain dehydrogenase reductase Sdr
LCF45_RS19675	COG1408	metallophosphoesterase
LCF45_RS19720	COG2814	Major facilitator Superfamily
LCF45_RS19730	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LCF45_RS19740	COG3209	COG3209 Rhs family protein
LCF45_RS19750	COG2205	protein histidine kinase activity
LCF45_RS19760	COG0436	Aminotransferase
LCF45_RS19765	COG1609	Transcriptional regulator
LCF45_RS19770	COG3833	ABC-type maltose transport systems, permease component
LCF45_RS19775	COG1175	transmembrane transport
LCF45_RS19780	COG2182	Extracellular solute-binding protein
LCF45_RS19790	COG0366	Alpha amylase catalytic
LCF45_RS19795	COG3842	ATPase activity
LCF45_RS19835	COG0183	Belongs to the thiolase family
LCF45_RS19870	COG1695	Transcriptional regulator
LCF45_RS19875	COG1028	Short-chain dehydrogenase reductase Sdr
LCF45_RS19885	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
LCF45_RS19890	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
LCF45_RS19895	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LCF45_RS19900	COG0436	Aminotransferase
LCF45_RS19905	COG1850	ribulose-bisphosphate carboxylase activity
LCF45_RS19910	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
LCF45_RS19915	COG0235	Class ii aldolase
LCF45_RS19920	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
LCF45_RS19935	COG2084	Dehydrogenase
LCF45_RS19945	COG2199	diguanylate cyclase activity
LCF45_RS19950	COG0778	Nitroreductase
LCF45_RS19975	COG1263	PTS System
LCF45_RS19975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCF45_RS19975	COG2190	(PTS) system
LCF45_RS19980	COG3711	transcriptional antiterminator
LCF45_RS19990	COG2188	Transcriptional regulator
LCF45_RS19995	COG0363	glucosamine-6-phosphate deaminase activity
LCF45_RS20000	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LCF45_RS20010	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LCF45_RS20015	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LCF45_RS20025	COG1547	Domain of unknown function (DUF309)
LCF45_RS20035	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LCF45_RS20040	COG4086	secreted protein
LCF45_RS20045	COG0561	phosphatase activity
LCF45_RS20050	COG0697	spore germination
LCF45_RS20065	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LCF45_RS20105	COG1686	Belongs to the peptidase S11 family
LCF45_RS20110	COG1725	Transcriptional regulator
LCF45_RS20115	COG1131	(ABC) transporter
LCF45_RS20135	COG1846	Transcriptional regulator
LCF45_RS20150	COG0598	Magnesium transport protein CorA
LCF45_RS20165	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LCF45_RS20175	COG4974	Belongs to the 'phage' integrase family
LCF45_RS20185	COG0735	belongs to the Fur family
LCF45_RS20190	COG1300	Membrane
LCF45_RS20210	COG0667	Aldo Keto reductase
LCF45_RS20215	COG0656	L-ascorbic acid biosynthetic process
LCF45_RS20220	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LCF45_RS20220	COG0456	acetyltransferase
LCF45_RS20230	COG1525	nuclease
LCF45_RS20230	COG4085	toxin activity
LCF45_RS20230	COG0737	Belongs to the 5'-nucleotidase family
LCF45_RS20235	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
LCF45_RS20245	COG0596	Alpha beta hydrolase
LCF45_RS20250	COG2056	Na+-H+ antiporter family
LCF45_RS20255	COG1609	Transcriptional regulator
LCF45_RS20260	COG0456	acetyltransferase
LCF45_RS20265	COG1073	alpha beta
LCF45_RS20280	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LCF45_RS20280	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LCF45_RS20285	COG0307	riboflavin synthase, alpha
LCF45_RS20290	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LCF45_RS20290	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LCF45_RS20305	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LCF45_RS20310	COG4106	trans-aconitate 2-methyltransferase activity
LCF45_RS20315	COG2226	methyltransferase
LCF45_RS20315	COG1073	alpha beta
LCF45_RS20320	COG0156	8-amino-7-oxononanoate synthase activity
LCF45_RS20330	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LCF45_RS20340	COG1757	Na H antiporter
LCF45_RS20345	COG0737	Belongs to the 5'-nucleotidase family
LCF45_RS20355	COG1522	sequence-specific DNA binding
LCF45_RS20390	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LCF45_RS20400	COG0300	oxidoreductase activity
LCF45_RS20405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LCF45_RS20410	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LCF45_RS20415	COG1760	l-serine dehydratase
LCF45_RS20420	COG1760	l-serine dehydratase
LCF45_RS20430	COG1234	tRNA 3'-trailer cleavage
LCF45_RS20445	COG1285	pathogenesis
LCF45_RS20460	COG2195	Cleaves the N-terminal amino acid of tripeptides
LCF45_RS20465	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LCF45_RS20480	COG1376	ErfK ybiS ycfS ynhG family protein
LCF45_RS20485	COG4129	membrane
LCF45_RS20490	COG1126	abc transporter atp-binding protein
LCF45_RS20495	COG0765	amino acid transport
LCF45_RS20500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LCF45_RS20515	COG2816	NAD+ diphosphatase activity
LCF45_RS20520	COG2323	membrane
LCF45_RS20525	COG0772	Belongs to the SEDS family
LCF45_RS20530	COG0508	dehydrogenase complex catalyzes the overall conversion of
LCF45_RS20535	COG0022	dehydrogenase e1 component
LCF45_RS20540	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LCF45_RS20545	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LCF45_RS20550	COG3426	butyrate kinase activity
LCF45_RS20560	COG0280	phosphate acetyltransferase
LCF45_RS20565	COG3829	transcription factor binding
LCF45_RS20565	COG3290	protein histidine kinase activity
LCF45_RS20575	COG0584	glycerophosphoryl diester phosphodiesterase
LCF45_RS20580	COG3093	addiction module antidote protein HigA
LCF45_RS20615	COG0745	RESPONSE REGULATOR receiver
LCF45_RS20620	COG0750	zinc metalloprotease
LCF45_RS20625	COG0497	DNA recombination
LCF45_RS20630	COG1438	arginine binding
LCF45_RS20635	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
LCF45_RS20640	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LCF45_RS20645	COG0142	geranyltranstransferase activity
LCF45_RS20650	COG1722	exodeoxyribonuclease VII activity
LCF45_RS20655	COG1570	exodeoxyribonuclease VII activity
LCF45_RS20660	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LCF45_RS20665	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LCF45_RS20670	COG1302	Protein conserved in bacteria
LCF45_RS20675	COG0439	Biotin carboxylase
LCF45_RS20680	COG0511	ligase activity, forming carbon-carbon bonds
LCF45_RS20725	COG3854	ATPases associated with a variety of cellular activities
LCF45_RS20745	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LCF45_RS20750	COG0006	proline dipeptidase activity
LCF45_RS20755	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LCF45_RS20765	COG3872	metal-dependent enzyme
LCF45_RS20775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LCF45_RS20815	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LCF45_RS20825	COG1609	Transcriptional regulator
LCF45_RS20835	COG2076	Multidrug Resistance protein
LCF45_RS20840	COG2076	Multidrug Resistance protein
LCF45_RS20880	COG1725	Transcriptional regulator
LCF45_RS20895	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LCF45_RS20900	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LCF45_RS20905	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LCF45_RS20910	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LCF45_RS20940	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LCF45_RS20965	COG4970	Tfp pilus assembly protein FimT
LCF45_RS20975	COG1459	type II secretion system
LCF45_RS20980	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LCF45_RS21035	COG0646	methionine synthase
LCF45_RS21035	COG1410	methionine synthase
LCF45_RS21040	COG0646	methionine synthase
LCF45_RS21040	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LCF45_RS21045	COG0626	cystathionine gamma-synthase activity
LCF45_RS21050	COG0626	cystathionine gamma-synthase activity
LCF45_RS21070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LCF45_RS21080	COG1940	carbohydrate kinase activity
LCF45_RS21085	COG4483	Protein conserved in bacteria
LCF45_RS21090	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LCF45_RS21095	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LCF45_RS21100	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LCF45_RS21105	COG0704	Plays a role in the regulation of phosphate uptake
LCF45_RS21115	COG0581	inorganic phosphate transmembrane transporter activity
LCF45_RS21120	COG0573	inorganic phosphate transmembrane transporter activity
LCF45_RS21125	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LCF45_RS21130	COG0768	penicillin binding
LCF45_RS21135	COG0477	Major facilitator Superfamily
LCF45_RS21140	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LCF45_RS21160	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LCF45_RS21165	COG0735	belongs to the Fur family
LCF45_RS21170	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LCF45_RS21175	COG1121	(ABC) transporter
LCF45_RS21180	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LCF45_RS21190	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LCF45_RS21205	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LCF45_RS21210	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LCF45_RS21215	COG2384	SAM-dependent methyltransferase
LCF45_RS21220	COG2010	Cytochrome c
LCF45_RS21225	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LCF45_RS21230	COG0358	DNA primase activity
LCF45_RS21240	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LCF45_RS21245	COG0517	IMP dehydrogenase activity
LCF45_RS21250	COG1381	Involved in DNA repair and RecF pathway recombination
LCF45_RS21260	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LCF45_RS21265	COG0295	cytidine deaminase activity
LCF45_RS21270	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LCF45_RS21275	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LCF45_RS21280	COG1480	7TM receptor with intracellular HD hydrolase
LCF45_RS21285	COG1702	phosphate starvation-inducible protein PhoH
LCF45_RS21300	COG1610	YqeY-like protein
LCF45_RS21305	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LCF45_RS21310	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LCF45_RS21315	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LCF45_RS21325	COG0484	heat shock protein binding
LCF45_RS21330	COG0443	Heat shock 70 kDa protein
LCF45_RS21340	COG1420	regulation of RNA biosynthetic process
LCF45_RS21345	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LCF45_RS21350	COG1733	regulation of RNA biosynthetic process
LCF45_RS21355	COG0481	GTPase activity
LCF45_RS21365	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LCF45_RS21370	COG0268	Binds directly to 16S ribosomal RNA
LCF45_RS21375	COG1466	dna polymerase III delta subunit
LCF45_RS21385	COG0658	competence protein
LCF45_RS21385	COG2333	competence protein COMEC
LCF45_RS21390	COG2131	deaminase
LCF45_RS21395	COG1555	photosystem II stabilization
LCF45_RS21395	COG1596	polysaccharide export
LCF45_RS21400	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LCF45_RS21405	COG2226	methyltransferase
LCF45_RS21410	COG0799	negative regulation of ribosome biogenesis
LCF45_RS21415	COG1713	HD superfamily hydrolase involved in NAD metabolism
LCF45_RS21420	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LCF45_RS21425	COG1534	Rna-binding protein
LCF45_RS21430	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LCF45_RS21435	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LCF45_RS21440	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
LCF45_RS21450	COG0688	phosphatidylethanolamine metabolic process
LCF45_RS21460	COG1595	DNA-templated transcription, initiation
LCF45_RS21465	COG2357	RelA SpoT domain protein
LCF45_RS21475	COG1785	Belongs to the alkaline phosphatase family
LCF45_RS21485	COG2267	carboxylic ester hydrolase activity
LCF45_RS21520	COG1404	Belongs to the peptidase S8 family
LCF45_RS21525	COG3186	Phenylalanine-4-hydroxylase
LCF45_RS21530	COG2154	pterin-4-alpha-carbinolamine dehydratase
LCF45_RS21535	COG2514	catechol 2,3-dioxygenase activity
LCF45_RS21540	COG2259	Doxx family
LCF45_RS21580	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LCF45_RS21590	COG1012	belongs to the aldehyde dehydrogenase family
LCF45_RS21590	COG1454	alcohol dehydrogenase
LCF45_RS21595	COG0626	cystathionine gamma-synthase activity
LCF45_RS21600	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LCF45_RS21605	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LCF45_RS21610	COG2226	methyltransferase
LCF45_RS21625	COG0768	penicillin binding
LCF45_RS21630	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LCF45_RS21635	COG0572	uridine kinase
LCF45_RS21640	COG0826	peptidase U32
LCF45_RS21645	COG0826	peptidase U32
LCF45_RS21650	COG4122	O-methyltransferase activity
LCF45_RS21655	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LCF45_RS21665	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LCF45_RS21670	COG4472	Bacterial protein of unknown function (DUF965)
LCF45_RS21675	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LCF45_RS21685	COG0628	permease
LCF45_RS21705	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LCF45_RS21715	COG0482	sulfurtransferase activity
LCF45_RS21720	COG1104	cysteine desulfurase activity
LCF45_RS21725	COG1959	2 iron, 2 sulfur cluster binding
LCF45_RS21730	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LCF45_RS21740	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LCF45_RS21745	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LCF45_RS21760	COG1490	D-aminoacyl-tRNA deacylase activity
LCF45_RS21765	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LCF45_RS21770	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LCF45_RS21775	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LCF45_RS21775	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LCF45_RS21780	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LCF45_RS21785	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LCF45_RS21785	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LCF45_RS21795	COG2244	polysaccharide biosynthetic process
LCF45_RS21800	COG2323	membrane
LCF45_RS21810	COG1862	Preprotein translocase
LCF45_RS21815	COG0343	queuine tRNA-ribosyltransferase activity
LCF45_RS21820	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LCF45_RS21830	COG2255	four-way junction helicase activity
LCF45_RS21835	COG0632	four-way junction helicase activity
LCF45_RS21840	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
LCF45_RS21865	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LCF45_RS21870	COG0157	Belongs to the NadC ModD family
LCF45_RS21875	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LCF45_RS21880	COG1104	cysteine desulfurase activity
LCF45_RS21885	COG1827	regulation of RNA biosynthetic process
LCF45_RS21890	COG2258	MOSC domain
LCF45_RS21895	COG0077	Prephenate dehydratase
LCF45_RS21900	COG0577	efflux transmembrane transporter activity
LCF45_RS21905	COG0577	efflux transmembrane transporter activity
LCF45_RS21910	COG1136	(ABC) transporter
LCF45_RS21915	COG5002	protein histidine kinase activity
LCF45_RS21920	COG0745	RESPONSE REGULATOR receiver
LCF45_RS21925	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LCF45_RS21930	COG3290	protein histidine kinase activity
LCF45_RS21940	COG2868	ribosomal protein
LCF45_RS21950	COG1530	ribonuclease E activity
LCF45_RS21955	COG1994	Peptidase M50
LCF45_RS21960	COG0739	heme binding
LCF45_RS21965	COG2894	cell division
LCF45_RS21970	COG0850	regulation of cytokinetic process
LCF45_RS21985	COG1077	Cell shape determining protein MreB Mrl
LCF45_RS21990	COG2003	Belongs to the UPF0758 family
LCF45_RS21995	COG0424	maF-like protein
LCF45_RS22005	COG0285	dihydrofolate synthase activity
LCF45_RS22020	COG1388	LysM domain
LCF45_RS22025	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LCF45_RS22030	COG0113	porphobilinogen synthase activity
LCF45_RS22035	COG1587	Uroporphyrinogen-III synthase
LCF45_RS22040	COG0181	hydroxymethylbilane synthase activity
LCF45_RS22045	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LCF45_RS22050	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LCF45_RS22055	COG1846	Transcriptional regulator
LCF45_RS22060	COG1764	response to oxidative stress
LCF45_RS22065	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LCF45_RS22075	COG0470	DNA polymerase III
LCF45_RS22075	COG1067	ATP-dependent peptidase activity
LCF45_RS22085	COG0544	peptidyl-prolyl cis-trans isomerase activity
LCF45_RS22115	COG0622	Phosphoesterase
LCF45_RS22125	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LCF45_RS22130	COG5401	PFAM Sporulation and spore germination
LCF45_RS22140	COG0477	Major facilitator Superfamily
LCF45_RS22145	COG2197	response regulator
LCF45_RS22150	COG2233	PERMEase
LCF45_RS22155	COG0402	S-adenosylhomocysteine deaminase activity
LCF45_RS22160	COG1983	PspC domain protein
LCF45_RS22165	COG1396	sequence-specific DNA binding
LCF45_RS22170	COG0697	spore germination
LCF45_RS22180	COG1959	2 iron, 2 sulfur cluster binding
LCF45_RS22185	COG1668	transmembrane transport
LCF45_RS22190	COG4152	abc transporter atp-binding protein
LCF45_RS22195	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
LCF45_RS22200	COG1360	Flagellar Motor Protein
LCF45_RS22205	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LCF45_RS22210	COG1876	peptidase activity
LCF45_RS22215	COG0824	Thioesterase
LCF45_RS22220	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LCF45_RS22225	COG1053	succinate dehydrogenase
LCF45_RS22230	COG2009	succinate dehydrogenase
LCF45_RS22235	COG1719	4-vinyl reductase, 4VR
LCF45_RS22240	COG0322	excinuclease ABC activity
LCF45_RS22245	COG3118	belongs to the thioredoxin family
LCF45_RS22250	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LCF45_RS22255	COG2086	electron transfer activity
LCF45_RS22260	COG1024	Enoyl-CoA hydratase
LCF45_RS22265	COG1309	transcriptional regulator
LCF45_RS22270	COG0318	PFAM AMP-dependent synthetase and ligase
LCF45_RS22290	COG2318	DinB family
LCF45_RS22315	COG1131	(ABC) transporter
LCF45_RS22320	COG2205	protein histidine kinase activity
LCF45_RS22325	COG0745	RESPONSE REGULATOR receiver
LCF45_RS22335	COG4895	conserved protein (DUF2196)
LCF45_RS22340	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LCF45_RS22345	COG2329	Antibiotic biosynthesis monooxygenase
LCF45_RS22350	COG4509	Sortase family
LCF45_RS22355	COG1120	ATPase activity
LCF45_RS22370	COG5386	Cell surface protein
LCF45_RS22380	COG5386	Cell surface protein
LCF45_RS22385	COG1114	Component of the transport system for branched-chain amino acids
LCF45_RS22395	COG1193	negative regulation of DNA recombination
LCF45_RS22400	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LCF45_RS22400	COG1796	DNA polymerase
LCF45_RS22405	COG1286	toxin biosynthetic process
LCF45_RS22410	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LCF45_RS22415	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LCF45_RS22440	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LCF45_RS22445	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LCF45_RS22455	COG1418	mRNA catabolic process
LCF45_RS22485	COG2814	Major facilitator Superfamily
LCF45_RS22490	COG1566	PFAM secretion protein HlyD family protein
LCF45_RS22495	COG1309	transcriptional regulator
LCF45_RS22500	COG1363	Peptidase, m42
LCF45_RS22510	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LCF45_RS22525	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LCF45_RS22535	COG1484	DNA-dependent DNA replication
LCF45_RS22540	COG3611	Membrane attachment protein
LCF45_RS22545	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LCF45_RS22550	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
LCF45_RS22555	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LCF45_RS22560	COG0237	dephospho-CoA kinase activity
LCF45_RS22565	COG1971	Probably functions as a manganese efflux pump
LCF45_RS22575	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LCF45_RS22575	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LCF45_RS22580	COG5002	protein histidine kinase activity
LCF45_RS22585	COG0745	RESPONSE REGULATOR receiver
LCF45_RS22605	COG0039	L-malate dehydrogenase activity
LCF45_RS22610	COG0538	isocitrate dehydrogenase activity
LCF45_RS22615	COG0372	Belongs to the citrate synthase family
LCF45_RS22625	COG0628	permease
LCF45_RS22630	COG3030	protein affecting phage T7 exclusion by the F plasmid
LCF45_RS22640	COG0205	6-phosphofructokinase activity
LCF45_RS22650	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LCF45_RS22655	COG1725	Transcriptional regulator
LCF45_RS22660	COG0281	malic enzyme
LCF45_RS22665	COG0587	DNA-directed DNA polymerase activity
LCF45_RS22680	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LCF45_RS22695	COG4109	DRTGG domain
LCF45_RS22710	COG0006	proline dipeptidase activity
LCF45_RS22740	COG0662	Cupin 2, conserved barrel domain protein
LCF45_RS22750	COG1476	TRANSCRIPTIONal
LCF45_RS22765	COG1028	Short-chain dehydrogenase reductase Sdr
LCF45_RS22770	COG0589	response to stress
LCF45_RS22790	COG0165	Argininosuccinate lyase
LCF45_RS22795	COG0137	argininosuccinate synthase activity
LCF45_RS22810	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LCF45_RS22830	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LCF45_RS22835	COG0827	DNA restriction-modification system
LCF45_RS22840	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LCF45_RS22845	COG3874	Sporulation protein YtfJ
LCF45_RS22860	COG1574	metal-dependent hydrolase with the TIM-barrel fold
LCF45_RS22870	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LCF45_RS22885	COG1104	cysteine desulfurase activity
LCF45_RS22890	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LCF45_RS22905	COG1309	transcriptional regulator
LCF45_RS22910	COG1956	GAF domain-containing protein
LCF45_RS22915	COG0626	cystathionine gamma-synthase activity
LCF45_RS22920	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LCF45_RS22945	COG1595	DNA-templated transcription, initiation
LCF45_RS22955	COG0110	maltose O-acetyltransferase activity
LCF45_RS22960	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LCF45_RS22965	COG0454	-acetyltransferase
LCF45_RS22970	COG0517	IMP dehydrogenase activity
LCF45_RS22975	COG0123	including yeast histone deacetylase and acetoin utilization protein
LCF45_RS22980	COG2267	carboxylic ester hydrolase activity
LCF45_RS22990	COG0745	RESPONSE REGULATOR receiver
LCF45_RS22995	COG5002	protein histidine kinase activity
LCF45_RS23010	COG1970	mechanosensitive ion channel activity
LCF45_RS23030	COG1609	Transcriptional regulator
LCF45_RS23040	COG4851	CamS sex pheromone cAM373 precursor
LCF45_RS23045	COG3118	belongs to the thioredoxin family
LCF45_RS23055	COG2309	aminopeptidase activity
LCF45_RS23085	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LCF45_RS23110	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LCF45_RS23115	COG4848	Belongs to the UPF0354 family
LCF45_RS23120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LCF45_RS23125	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
LCF45_RS23130	COG1363	Peptidase, m42
LCF45_RS23140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LCF45_RS23145	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LCF45_RS23155	COG0510	thiamine kinase activity
LCF45_RS23160	COG1523	belongs to the glycosyl hydrolase 13 family
LCF45_RS23170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LCF45_RS23175	COG1349	DNA-binding transcription factor activity
LCF45_RS23180	COG1187	pseudouridine synthase activity
LCF45_RS23185	COG2244	polysaccharide biosynthetic process
LCF45_RS23190	COG2081	HI0933 family
LCF45_RS23195	COG2814	Major facilitator Superfamily
LCF45_RS23205	COG3832	glyoxalase III activity
LCF45_RS23225	COG1329	Transcriptional regulator
LCF45_RS23250	COG0314	molybdopterin synthase activity
LCF45_RS23255	COG1763	Mo-molybdopterin cofactor biosynthetic process
LCF45_RS23260	COG0303	'Molybdopterin
LCF45_RS23265	COG0315	cyclic pyranopterin monophosphate synthase activity
LCF45_RS23270	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LCF45_RS23275	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LCF45_RS23295	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LCF45_RS23305	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LCF45_RS23345	COG0495	leucyl-tRNA aminoacylation
LCF45_RS23350	COG2814	Major facilitator Superfamily
LCF45_RS23355	COG0475	glutathione-regulated potassium exporter activity
LCF45_RS23360	COG0490	domain, Protein
LCF45_RS23365	COG0582	viral genome integration into host DNA
LCF45_RS23375	COG1136	(ABC) transporter
LCF45_RS23390	COG1242	4 iron, 4 sulfur cluster binding
LCF45_RS23395	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
LCF45_RS23400	COG1131	(ABC) transporter
LCF45_RS23410	COG1794	racemase activity, acting on amino acids and derivatives
LCF45_RS23425	COG2267	carboxylic ester hydrolase activity
LCF45_RS23430	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LCF45_RS23435	COG0671	phosphoesterase, PA-phosphatase related
LCF45_RS23440	COG0438	transferase activity, transferring glycosyl groups
LCF45_RS23455	COG0746	molybdenum cofactor guanylyltransferase activity
LCF45_RS23475	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LCF45_RS23480	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LCF45_RS23520	COG5002	protein histidine kinase activity
LCF45_RS23525	COG3852	Histidine kinase
LCF45_RS23530	COG0753	catalase activity
LCF45_RS23535	COG2267	carboxylic ester hydrolase activity
LCF45_RS23545	COG1368	sulfuric ester hydrolase activity
LCF45_RS23555	COG4895	conserved protein (DUF2196)
LCF45_RS23570	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LCF45_RS23575	COG1116	anion transmembrane transporter activity
LCF45_RS23580	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LCF45_RS23605	COG0494	nUDIX hydrolase
LCF45_RS23640	COG2076	Multidrug Resistance protein
LCF45_RS23645	COG2076	Multidrug Resistance protein
LCF45_RS23650	COG0789	Transcriptional regulator
LCF45_RS23655	COG1854	S-ribosylhomocysteine lyase activity
LCF45_RS23665	COG0288	reversible hydration of carbon dioxide
LCF45_RS23670	COG1271	oxidase subunit
LCF45_RS23675	COG1294	oxidase, subunit
LCF45_RS23695	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LCF45_RS23720	COG1842	Phage shock protein A
LCF45_RS23745	COG3859	Proton-coupled thiamine transporter YuaJ
LCF45_RS23750	COG5002	protein histidine kinase activity
LCF45_RS23755	COG0745	RESPONSE REGULATOR receiver
LCF45_RS23780	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LCF45_RS23785	COG1597	lipid kinase activity
LCF45_RS23800	COG1136	(ABC) transporter
LCF45_RS23815	COG5002	protein histidine kinase activity
LCF45_RS23825	COG0586	Pfam SNARE associated Golgi protein
LCF45_RS23840	COG0577	efflux transmembrane transporter activity
LCF45_RS23845	COG1136	(ABC) transporter
LCF45_RS23850	COG2207	Transcriptional regulator
LCF45_RS23850	COG3708	Transcriptional regulator
LCF45_RS23860	COG1131	(ABC) transporter
LCF45_RS23865	COG5658	integral membrane protein
LCF45_RS23870	COG0640	Transcriptional regulator
LCF45_RS23875	COG0745	RESPONSE REGULATOR receiver
LCF45_RS23880	COG2205	protein histidine kinase activity
LCF45_RS23885	COG0577	efflux transmembrane transporter activity
LCF45_RS23890	COG0577	efflux transmembrane transporter activity
LCF45_RS23895	COG1136	(ABC) transporter
LCF45_RS23900	COG0577	efflux transmembrane transporter activity
LCF45_RS23915	COG2188	Transcriptional regulator
LCF45_RS23935	COG3964	amidohydrolase
LCF45_RS23955	COG4948	Mandelate Racemase Muconate Lactonizing
LCF45_RS23960	COG0318	PFAM AMP-dependent synthetase and ligase
LCF45_RS23975	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LCF45_RS23985	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LCF45_RS23990	COG1169	isochorismate synthase
LCF45_RS23995	COG1575	Belongs to the MenA family. Type 1 subfamily
LCF45_RS24000	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LCF45_RS24005	COG1278	Cold shock
LCF45_RS24015	COG0789	Transcriptional regulator
LCF45_RS24025	COG0058	SHG alpha-glucan phosphorylase activity
LCF45_RS24035	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LCF45_RS24040	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LCF45_RS24045	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LCF45_RS24075	COG1595	DNA-templated transcription, initiation
LCF45_RS24205	COG1285	pathogenesis
LCF45_RS24210	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LCF45_RS24220	COG0166	Belongs to the GPI family
LCF45_RS24225	COG2155	Conserved Protein
LCF45_RS24230	COG1098	S1 RNA binding domain
LCF45_RS24235	COG0436	Aminotransferase
LCF45_RS24240	COG1522	sequence-specific DNA binding
LCF45_RS24245	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LCF45_RS24250	COG2267	carboxylic ester hydrolase activity
LCF45_RS24260	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LCF45_RS24280	COG5018	Exonuclease
LCF45_RS24285	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LCF45_RS24305	COG2050	protein possibly involved in aromatic compounds catabolism
LCF45_RS24315	COG1268	BioY protein
LCF45_RS24325	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LCF45_RS24330	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LCF45_RS24340	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LCF45_RS24345	COG3584	3D domain protein
LCF45_RS24360	COG1252	NADH dehydrogenase
LCF45_RS24365	COG0492	ferredoxin-NADP+ reductase activity
LCF45_RS24370	COG3708	Transcriptional regulator
LCF45_RS24385	COG1683	Conserved Protein
LCF45_RS24410	COG0316	Belongs to the HesB IscA family
LCF45_RS24415	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LCF45_RS24420	COG4844	belongs to the
LCF45_RS24425	COG1252	NADH dehydrogenase
LCF45_RS24435	COG0390	transport system, permease component
LCF45_RS24440	COG2824	Alkylphosphonate utilization operon protein PhnA
LCF45_RS24465	COG4837	Protein of unknown function (DUF1462)
LCF45_RS24470	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
LCF45_RS24480	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LCF45_RS24485	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LCF45_RS24500	COG0577	efflux transmembrane transporter activity
LCF45_RS24500	COG1136	(ABC) transporter
LCF45_RS24505	COG2249	NAD(P)H dehydrogenase (quinone) activity
LCF45_RS24515	COG0647	UMP catabolic process
LCF45_RS24525	COG2445	Protein of unknown function DUF86
LCF45_RS24530	COG1494	fructose-1,6-bisphosphatase
LCF45_RS24545	COG4470	Protein conserved in bacteria
LCF45_RS24555	COG0789	Transcriptional regulator
LCF45_RS24560	COG4377	Putative membrane peptidase family (DUF2324)
LCF45_RS24580	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LCF45_RS24585	COG0739	heme binding
LCF45_RS24595	COG3377	Domain of unknown function (DUF1805)
LCF45_RS24600	COG0737	Belongs to the 5'-nucleotidase family
LCF45_RS24605	COG0719	Fe-S assembly protein
LCF45_RS24610	COG0822	iron-sulfur transferase activity
LCF45_RS24615	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LCF45_RS24620	COG0719	Fe-S assembly protein
LCF45_RS24625	COG0396	ATPase activity
LCF45_RS24630	COG1464	Belongs to the NlpA lipoprotein family
LCF45_RS24635	COG1464	Belongs to the NlpA lipoprotein family
LCF45_RS24640	COG2011	ABC-type metal ion transport system permease component
LCF45_RS24645	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LCF45_RS24655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LCF45_RS24660	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LCF45_RS24665	COG0509	glycine decarboxylation via glycine cleavage system
LCF45_RS24670	COG1393	Belongs to the ArsC family
LCF45_RS24705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LCF45_RS24710	COG1960	acyl-CoA dehydrogenase activity
LCF45_RS24715	COG0183	Belongs to the thiolase family
LCF45_RS24720	COG1024	Enoyl-CoA hydratase
LCF45_RS24720	COG1250	3-hydroxyacyl-CoA dehydrogenase
LCF45_RS24730	COG1686	Belongs to the peptidase S11 family
LCF45_RS24735	COG0506	proline dehydrogenase activity
LCF45_RS24745	COG0011	TIGRFAM Protein of
LCF45_RS24750	COG0840	transmembrane signaling receptor activity
LCF45_RS24765	COG2814	Major facilitator Superfamily
LCF45_RS24770	COG0531	amino acid
LCF45_RS24795	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LCF45_RS24825	COG0586	Pfam SNARE associated Golgi protein
LCF45_RS24835	COG1376	ErfK ybiS ycfS ynhG family protein
LCF45_RS24840	COG0745	RESPONSE REGULATOR receiver
LCF45_RS24845	COG5002	protein histidine kinase activity
LCF45_RS24855	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LCF45_RS24865	COG0840	transmembrane signaling receptor activity
LCF45_RS24870	COG0840	transmembrane signaling receptor activity
LCF45_RS24875	COG2151	metal-sulfur cluster biosynthetic enzyme
LCF45_RS24880	COG3227	Zinc metalloprotease (Elastase)
LCF45_RS24885	COG1741	Belongs to the pirin family
LCF45_RS24900	COG0586	Pfam SNARE associated Golgi protein
LCF45_RS24905	COG0475	glutathione-regulated potassium exporter activity
LCF45_RS24910	COG0490	domain, Protein
LCF45_RS24915	COG1115	amino acid carrier protein
LCF45_RS24920	COG0783	Belongs to the Dps family
LCF45_RS24930	COG2318	DinB family
LCF45_RS24935	COG1611	Belongs to the LOG family
LCF45_RS24945	COG1528	Iron-storage protein
LCF45_RS24950	COG2311	Membrane
LCF45_RS24955	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LCF45_RS24960	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LCF45_RS24965	COG1115	amino acid carrier protein
LCF45_RS24970	COG1115	amino acid carrier protein
LCF45_RS24975	COG2910	NAD(P)H-binding
LCF45_RS24990	COG0656	L-ascorbic acid biosynthetic process
LCF45_RS24995	COG2814	Major facilitator Superfamily
LCF45_RS25000	COG1733	regulation of RNA biosynthetic process
LCF45_RS25010	COG1252	NADH dehydrogenase
LCF45_RS25030	COG0840	transmembrane signaling receptor activity
LCF45_RS25030	COG3290	protein histidine kinase activity
LCF45_RS25040	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LCF45_RS25060	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LCF45_RS25075	COG4224	UPF0291 protein
LCF45_RS25080	COG1335	isochorismatase
LCF45_RS25085	COG1522	sequence-specific DNA binding
LCF45_RS25095	COG1522	sequence-specific DNA binding
LCF45_RS25100	COG0288	reversible hydration of carbon dioxide
LCF45_RS25105	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
LCF45_RS25110	COG2233	PERMEase
LCF45_RS25135	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LCF45_RS25150	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LCF45_RS25155	COG0557	exoribonuclease II activity
LCF45_RS25160	COG1647	Serine aminopeptidase, S33
LCF45_RS25165	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LCF45_RS25170	COG1346	cytolysis
LCF45_RS25185	COG0148	phosphopyruvate hydratase activity
LCF45_RS25195	COG0149	triose-phosphate isomerase activity
LCF45_RS25200	COG0126	phosphoglycerate kinase activity
LCF45_RS25205	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LCF45_RS25220	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LCF45_RS25255	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LCF45_RS25270	COG2323	membrane
LCF45_RS25280	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCF45_RS25285	COG1481	regulation of sporulation
LCF45_RS25290	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LCF45_RS25295	COG1660	Displays ATPase and GTPase activities
LCF45_RS25300	COG1051	belongs to the nudix hydrolase family
LCF45_RS25310	COG0492	ferredoxin-NADP+ reductase activity
LCF45_RS25315	COG0457	Tetratricopeptide repeat
LCF45_RS25320	COG0110	maltose O-acetyltransferase activity
LCF45_RS25325	COG0546	phosphoglycolate phosphatase activity
LCF45_RS25330	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LCF45_RS25335	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LCF45_RS25340	COG1950	PFAM Membrane protein of
LCF45_RS25345	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LCF45_RS25365	COG0789	Transcriptional regulator
LCF45_RS25400	COG0583	DNA-binding transcription factor activity
LCF45_RS25405	COG0789	Transcriptional regulator
LCF45_RS25410	COG0655	NAD(P)H dehydrogenase (quinone) activity
LCF45_RS25415	COG0488	(ABC) transporter
LCF45_RS25425	COG1132	(ABC) transporter
LCF45_RS25430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LCF45_RS25435	COG0793	Belongs to the peptidase S41A family
LCF45_RS25435	COG3409	Peptidoglycan-binding domain 1 protein
LCF45_RS25440	COG2177	Part of the ABC transporter FtsEX involved in
LCF45_RS25445	COG2884	Cell division ATP-binding protein ftsE
LCF45_RS25475	COG1131	(ABC) transporter
LCF45_RS25510	COG1278	Cold shock
LCF45_RS25515	COG1040	competence protein
LCF45_RS25520	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LCF45_RS25525	COG0791	NLP P60 protein
LCF45_RS25525	COG1388	LysM domain
LCF45_RS25530	COG1733	regulation of RNA biosynthetic process
LCF45_RS25535	COG1307	EDD domain protein, DegV family
LCF45_RS25540	COG1739	Uncharacterized protein family UPF0029
LCF45_RS25545	COG1316	TRANSCRIPTIONal
LCF45_RS25550	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LCF45_RS25555	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LCF45_RS25560	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LCF45_RS25570	COG3933	PFAM sigma-54 factor interaction domain-containing protein
LCF45_RS25570	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LCF45_RS25590	COG1486	melibiose metabolic process
LCF45_RS25595	COG1447	Phosphotransferase system cellobiose-specific component IIA
LCF45_RS25600	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LCF45_RS25620	COG1447	Phosphotransferase system cellobiose-specific component IIA
LCF45_RS25630	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LCF45_RS25635	COG1301	dicarboxylic acid transport
LCF45_RS25650	COG1511	domain protein
LCF45_RS25655	COG0583	DNA-binding transcription factor activity
LCF45_RS25660	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
LCF45_RS25670	COG1271	oxidase subunit
LCF45_RS25675	COG1294	oxidase, subunit
LCF45_RS25680	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LCF45_RS25685	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LCF45_RS25690	COG1620	l-lactate permease
LCF45_RS25700	COG2389	metal-binding protein
LCF45_RS25710	COG1368	sulfuric ester hydrolase activity
LCF45_RS25720	COG0791	NLP P60 protein
LCF45_RS25720	COG1388	LysM domain
LCF45_RS25725	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LCF45_RS25735	COG1215	transferase activity, transferring glycosyl groups
LCF45_RS25745	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LCF45_RS25750	COG1388	LysM domain
LCF45_RS25750	COG3584	3D domain protein
LCF45_RS25775	COG4715	Zinc finger, swim domain protein
LCF45_RS25780	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LCF45_RS25820	COG0577	efflux transmembrane transporter activity
LCF45_RS25825	COG1136	(ABC) transporter
LCF45_RS25860	COG5002	protein histidine kinase activity
LCF45_RS25860	COG3850	Histidine kinase
LCF45_RS25865	COG0745	RESPONSE REGULATOR receiver
LCF45_RS25885	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LCF45_RS25890	COG1134	teichoic acid transport
LCF45_RS25895	COG1682	transport, permease protein
LCF45_RS25900	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LCF45_RS25905	COG1215	transferase activity, transferring glycosyl groups
LCF45_RS25905	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LCF45_RS25915	COG1216	Glycosyl transferase, family 2
LCF45_RS25915	COG1442	glycosyl transferase family 8
LCF45_RS25935	COG1609	Transcriptional regulator
LCF45_RS25945	COG0726	polysaccharide deacetylase
LCF45_RS25955	COG0739	heme binding
LCF45_RS25970	COG3279	Response regulator of the LytR AlgR family
LCF45_RS25975	COG2385	sporulation resulting in formation of a cellular spore
LCF45_RS25990	COG4836	Membrane
LCF45_RS25995	COG1007	ATP synthesis coupled electron transport
LCF45_RS26000	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LCF45_RS26005	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LCF45_RS26010	COG0713	ATP synthesis coupled electron transport
LCF45_RS26015	COG0839	Belongs to the complex I subunit 6 family
LCF45_RS26025	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LCF45_RS26030	COG0649	NAD binding
LCF45_RS26035	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LCF45_RS26040	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LCF45_RS26045	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LCF45_RS26050	COG5001	Diguanylate cyclase
LCF45_RS26050	COG3300	MHYT domain
LCF45_RS26065	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LCF45_RS26070	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LCF45_RS26075	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LCF45_RS26080	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LCF45_RS26085	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LCF45_RS26090	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LCF45_RS26100	COG0356	it plays a direct role in the translocation of protons across the membrane
LCF45_RS26125	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LCF45_RS26135	COG0698	ribose 5-phosphate isomerase
LCF45_RS26145	COG2190	(PTS) system
LCF45_RS26150	COG2259	Doxx family
LCF45_RS26155	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LCF45_RS26170	COG1971	Probably functions as a manganese efflux pump
LCF45_RS26175	COG0009	L-threonylcarbamoyladenylate synthase
LCF45_RS26190	COG2890	protein-(glutamine-N5) methyltransferase activity
LCF45_RS26195	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LCF45_RS26200	COG1435	thymidine kinase activity
LCF45_RS26210	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LCF45_RS26215	COG1494	fructose-1,6-bisphosphatase
LCF45_RS26235	COG4821	SIS domain
LCF45_RS26240	COG0504	CTP synthase activity
LCF45_RS26245	COG3343	RNA polymerase activity
LCF45_RS26255	COG1960	acyl-CoA dehydrogenase activity
LCF45_RS26260	COG1960	acyl-CoA dehydrogenase activity
LCF45_RS26265	COG1250	3-hydroxyacyl-CoA dehydrogenase
LCF45_RS26270	COG0183	Belongs to the thiolase family
LCF45_RS26275	COG0247	lactate metabolic process
LCF45_RS26275	COG2181	nitrate reductase activity
LCF45_RS26280	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LCF45_RS26285	COG4294	response to UV
LCF45_RS26290	COG5001	Diguanylate cyclase
LCF45_RS26290	COG3300	MHYT domain
LCF45_RS26305	COG3227	Zinc metalloprotease (Elastase)
LCF45_RS26310	COG2197	response regulator
LCF45_RS26315	COG4585	Histidine kinase
LCF45_RS26320	COG0842	Transport permease protein
LCF45_RS26325	COG1131	(ABC) transporter
LCF45_RS26330	COG0024	Methionine aminopeptidase
LCF45_RS26335	COG2234	aminopeptidase activity
LCF45_RS26350	COG4506	Protein conserved in bacteria
LCF45_RS26355	COG1619	proteins homologs of microcin C7 resistance protein MccF
LCF45_RS26370	COG0010	Belongs to the arginase family
LCF45_RS26375	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LCF45_RS26380	COG2814	Major facilitator Superfamily
LCF45_RS26385	COG0789	Transcriptional regulator
LCF45_RS26390	COG0584	glycerophosphoryl diester phosphodiesterase
LCF45_RS26395	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LCF45_RS26405	COG1994	Peptidase M50
LCF45_RS26415	COG1078	dGTPase activity
LCF45_RS26420	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LCF45_RS26425	COG1120	ATPase activity
LCF45_RS26430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LCF45_RS26435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LCF45_RS26440	COG4844	belongs to the
LCF45_RS26455	COG0280	phosphate acetyltransferase
LCF45_RS26460	COG3253	May function as heme-dependent peroxidase
LCF45_RS26470	COG3773	Cell wall hydrolase
LCF45_RS26480	COG2363	Small membrane protein
LCF45_RS26495	COG2233	PERMEase
LCF45_RS26500	COG0561	phosphatase activity
LCF45_RS26505	COG2814	Major facilitator Superfamily
LCF45_RS26510	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LCF45_RS26515	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LCF45_RS26520	COG1131	(ABC) transporter
LCF45_RS26525	COG2755	lipolytic protein G-D-S-L family
LCF45_RS26530	COG1609	Transcriptional regulator
LCF45_RS26540	COG0460	homoserine dehydrogenase
LCF45_RS26545	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
LCF45_RS26550	COG2873	o-acetylhomoserine
LCF45_RS26565	COG2197	response regulator
LCF45_RS26570	COG4585	Histidine kinase
LCF45_RS26570	COG2203	Gaf domain
LCF45_RS26575	COG0351	phosphomethylpyrimidine kinase
LCF45_RS26580	COG3706	GGDEF domain
LCF45_RS26585	COG2879	small protein
LCF45_RS26590	COG1966	Carbon starvation protein
LCF45_RS26595	COG3279	Response regulator of the LytR AlgR family
LCF45_RS26600	COG0477	Major facilitator Superfamily
LCF45_RS26625	COG0840	transmembrane signaling receptor activity
LCF45_RS26635	COG1607	acyl-coa hydrolase
LCF45_RS26640	COG1216	Glycosyl transferase, family 2
LCF45_RS26650	COG1216	Glycosyl transferase, family 2
LCF45_RS26660	COG4485	Bacterial membrane protein, YfhO
LCF45_RS26665	COG0463	Glycosyl transferase, family 2
LCF45_RS26675	COG1309	transcriptional regulator
LCF45_RS26680	COG0488	(ABC) transporter
LCF45_RS26685	COG1309	transcriptional regulator
LCF45_RS26690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LCF45_RS26695	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LCF45_RS26695	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LCF45_RS26700	COG0628	permease
LCF45_RS26710	COG1380	Effector of murein hydrolase LrgA
LCF45_RS26715	COG3279	Response regulator of the LytR AlgR family
LCF45_RS26720	COG3275	phosphorelay sensor kinase activity
LCF45_RS26725	COG2814	Major facilitator Superfamily
LCF45_RS26730	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LCF45_RS26735	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
LCF45_RS26740	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LCF45_RS26790	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LCF45_RS26795	COG1272	protein, Hemolysin III
LCF45_RS26820	COG1164	Oligoendopeptidase f
LCF45_RS26830	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LCF45_RS26840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LCF45_RS26845	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LCF45_RS26850	COG4853	Protein conserved in bacteria
LCF45_RS26860	COG5002	protein histidine kinase activity
LCF45_RS26865	COG0745	RESPONSE REGULATOR receiver
LCF45_RS26895	COG0305	Participates in initiation and elongation during chromosome replication
LCF45_RS26900	COG0359	binds to the 23S rRNA
LCF45_RS26905	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
LCF45_RS26910	COG4241	membrane
LCF45_RS26920	COG0629	single-stranded DNA binding
LCF45_RS26925	COG0360	Binds together with S18 to 16S ribosomal RNA
LCF45_RS26930	COG0012	GTP binding
LCF45_RS26935	COG4481	Protein conserved in bacteria
LCF45_RS26940	COG0668	transmembrane transport
LCF45_RS26950	COG1475	DNA binding
LCF45_RS26955	COG1192	Involved in chromosome partitioning
LCF45_RS26960	COG1475	DNA binding
LCF45_RS26965	COG0357	Ribosomal RNA small subunit methyltransferase G
LCF45_RS26970	COG0445	tRNA wobble uridine modification
LCF45_RS26975	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LCF45_RS26980	COG1847	R3H domain protein
LCF45_RS26985	COG0706	membrane insertase activity
LCF45_RS26990	COG0594	ribonuclease P activity
LCF45_RS26995	COG0230	Belongs to the bacterial ribosomal protein bL34 family