locus-tag	class	description
A9C19_RS00015	COG4499	WXG100 protein secretion system (Wss), protein YukC
A9C19_RS00030	COG4499	WXG100 protein secretion system (Wss), protein YukC
A9C19_RS00055	COG1511	domain protein
A9C19_RS00060	COG1511	domain protein
A9C19_RS00095	COG0840	transmembrane signaling receptor activity
A9C19_RS00095	COG5278	phosphoserine phosphatase activity
A9C19_RS00100	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A9C19_RS00105	COG2195	Cleaves the N-terminal amino acid of tripeptides
A9C19_RS00115	COG2188	Transcriptional regulator
A9C19_RS00120	COG0366	Alpha amylase catalytic
A9C19_RS00130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A9C19_RS00130	COG1263	PTS System
A9C19_RS00150	COG2966	Psort location CytoplasmicMembrane, score
A9C19_RS00160	COG0788	formyltetrahydrofolate deformylase activity
A9C19_RS00170	COG1587	Uroporphyrinogen-III synthase
A9C19_RS00180	COG1695	Transcriptional regulator
A9C19_RS00195	COG0723	plastoquinol--plastocyanin reductase activity
A9C19_RS00195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A9C19_RS00220	COG2197	response regulator
A9C19_RS00225	COG1366	Belongs to the anti-sigma-factor antagonist family
A9C19_RS00235	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A9C19_RS00235	COG0551	DNA topoisomerase type I activity
A9C19_RS00250	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A9C19_RS00260	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
A9C19_RS00270	COG0477	Major facilitator Superfamily
A9C19_RS00275	COG0778	Nitroreductase
A9C19_RS00300	COG1028	Short-chain dehydrogenase reductase Sdr
A9C19_RS00305	COG0492	ferredoxin-NADP+ reductase activity
A9C19_RS00325	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
A9C19_RS00350	COG2363	Small membrane protein
A9C19_RS00370	COG0280	phosphate acetyltransferase
A9C19_RS00380	COG2217	Heavy metal translocating P-type atpase
A9C19_RS00390	COG4844	belongs to the
A9C19_RS00400	COG1078	dGTPase activity
A9C19_RS00405	COG3465	dGTPase activity
A9C19_RS00410	COG0783	Belongs to the Dps family
A9C19_RS00415	COG1994	Peptidase M50
A9C19_RS00425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A9C19_RS00430	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
A9C19_RS00440	COG2340	Cysteine-rich secretory protein family
A9C19_RS00445	COG4506	Protein conserved in bacteria
A9C19_RS00450	COG0018	arginyl-trna synthetase
A9C19_RS00465	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A9C19_RS00470	COG0247	lactate metabolic process
A9C19_RS00470	COG2181	nitrate reductase activity
A9C19_RS00475	COG0183	Belongs to the thiolase family
A9C19_RS00480	COG1250	3-hydroxyacyl-CoA dehydrogenase
A9C19_RS00485	COG1960	acyl-CoA dehydrogenase activity
A9C19_RS00490	COG1960	acyl-CoA dehydrogenase activity
A9C19_RS00500	COG1703	isobutyryl-CoA mutase activity
A9C19_RS00500	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A9C19_RS00500	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A9C19_RS00505	COG3343	RNA polymerase activity
A9C19_RS00510	COG0504	CTP synthase activity
A9C19_RS00515	COG1653	transport
A9C19_RS00520	COG1175	transmembrane transport
A9C19_RS00525	COG0395	ABC-type sugar transport system, permease component
A9C19_RS00540	COG0840	transmembrane signaling receptor activity
A9C19_RS00545	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
A9C19_RS00550	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A9C19_RS00555	COG1984	allophanate hydrolase subunit 2
A9C19_RS00560	COG4821	SIS domain
A9C19_RS00565	COG2204	response regulator
A9C19_RS00570	COG0191	fructose-bisphosphate aldolase activity
A9C19_RS00575	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
A9C19_RS00580	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
A9C19_RS00590	COG1435	thymidine kinase activity
A9C19_RS00600	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
A9C19_RS00610	COG0789	Transcriptional regulator
A9C19_RS00615	COG0346	lactoylglutathione lyase activity
A9C19_RS00620	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
A9C19_RS00635	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
A9C19_RS00640	COG0009	L-threonylcarbamoyladenylate synthase
A9C19_RS00645	COG1971	Probably functions as a manganese efflux pump
A9C19_RS00655	COG0523	cobalamin synthesis protein
A9C19_RS00660	COG1785	Belongs to the alkaline phosphatase family
A9C19_RS00665	COG1785	Belongs to the alkaline phosphatase family
A9C19_RS00670	COG0701	Predicted permease
A9C19_RS00685	COG0840	transmembrane signaling receptor activity
A9C19_RS00690	COG0698	ribose 5-phosphate isomerase
A9C19_RS00720	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
A9C19_RS00730	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
A9C19_RS00740	COG2059	Chromate
A9C19_RS00745	COG1404	Belongs to the peptidase S8 family
A9C19_RS00765	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
A9C19_RS00770	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
A9C19_RS00775	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
A9C19_RS00780	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
A9C19_RS00785	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
A9C19_RS00790	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
A9C19_RS00795	COG0355	proton-transporting ATP synthase activity, rotational mechanism
A9C19_RS00805	COG4836	Membrane
A9C19_RS00815	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
A9C19_RS00820	COG2385	sporulation resulting in formation of a cellular spore
A9C19_RS00830	COG0739	heme binding
A9C19_RS00850	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A9C19_RS00860	COG1609	Transcriptional regulator
A9C19_RS00865	COG1077	Cell shape determining protein MreB Mrl
A9C19_RS00875	COG4786	Flagellar basal body rod
A9C19_RS00880	COG4786	Flagellar basal body rod
A9C19_RS00910	COG3546	catalase activity
A9C19_RS00930	COG0629	single-stranded DNA binding
A9C19_RS00940	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A9C19_RS00950	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A9C19_RS00955	COG1501	Belongs to the glycosyl hydrolase 31 family
A9C19_RS00960	COG2188	Transcriptional regulator
A9C19_RS00975	COG2188	Transcriptional regulator
A9C19_RS00980	COG1012	belongs to the aldehyde dehydrogenase family
A9C19_RS00990	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A9C19_RS00995	COG4715	Zinc finger, swim domain protein
A9C19_RS01000	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A9C19_RS01010	COG2972	Histidine kinase
A9C19_RS01015	COG2207	Transcriptional regulator
A9C19_RS01015	COG4753	response regulator
A9C19_RS01025	COG1175	transmembrane transport
A9C19_RS01040	COG1940	carbohydrate kinase activity
A9C19_RS01055	COG3944	biosynthesis protein
A9C19_RS01060	COG0489	protein tyrosine kinase activity
A9C19_RS01070	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A9C19_RS01090	COG0438	transferase activity, transferring glycosyl groups
A9C19_RS01100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A9C19_RS01110	COG1215	transferase activity, transferring glycosyl groups
A9C19_RS01120	COG0438	transferase activity, transferring glycosyl groups
A9C19_RS01125	COG1216	Glycosyl transferase, family 2
A9C19_RS01130	COG5039	Polysaccharide pyruvyl transferase
A9C19_RS01135	COG2244	polysaccharide biosynthetic process
A9C19_RS01140	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A9C19_RS01240	COG1388	LysM domain
A9C19_RS01240	COG3103	Sh3 type 3 domain protein
A9C19_RS01240	COG0791	NLP P60 protein
A9C19_RS01265	COG0531	amino acid
A9C19_RS01280	COG2207	Transcriptional regulator
A9C19_RS01280	COG4753	response regulator
A9C19_RS01285	COG3275	phosphorelay sensor kinase activity
A9C19_RS01325	COG1116	anion transmembrane transporter activity
A9C19_RS01330	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A9C19_RS01340	COG0154	amidase activity
A9C19_RS01345	COG0730	response to heat
A9C19_RS01350	COG2188	Transcriptional regulator
A9C19_RS01355	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
A9C19_RS01360	COG0402	S-adenosylhomocysteine deaminase activity
A9C19_RS01435	COG1175	transmembrane transport
A9C19_RS01440	COG1653	transport
A9C19_RS01450	COG0483	inositol monophosphate 1-phosphatase activity
A9C19_RS01455	COG2188	Transcriptional regulator
A9C19_RS01465	COG0653	protein targeting
A9C19_RS01470	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
A9C19_RS01500	COG4464	protein tyrosine phosphatase activity
A9C19_RS01510	COG0601	transmembrane transport
A9C19_RS01515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A9C19_RS01520	COG4172	Belongs to the ABC transporter superfamily
A9C19_RS01525	COG0534	Mate efflux family protein
A9C19_RS01555	COG0367	asparagine synthase
A9C19_RS01575	COG2205	protein histidine kinase activity
A9C19_RS01580	COG0745	RESPONSE REGULATOR receiver
A9C19_RS01595	COG5001	Diguanylate cyclase
A9C19_RS01595	COG3300	MHYT domain
A9C19_RS01600	COG1114	Component of the transport system for branched-chain amino acids
A9C19_RS01605	COG1114	Component of the transport system for branched-chain amino acids
A9C19_RS01615	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
A9C19_RS01620	COG3853	Toxic anion resistance protein (TelA)
A9C19_RS01655	COG1316	TRANSCRIPTIONal
A9C19_RS01670	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A9C19_RS01680	COG0662	Cupin 2, conserved barrel domain protein
A9C19_RS01680	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
A9C19_RS01690	COG2244	polysaccharide biosynthetic process
A9C19_RS01695	COG4193	domain, Protein
A9C19_RS01695	COG5263	repeat protein
A9C19_RS01700	COG0438	transferase activity, transferring glycosyl groups
A9C19_RS01720	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A9C19_RS01725	COG1215	transferase activity, transferring glycosyl groups
A9C19_RS01730	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A9C19_RS01735	COG1739	Uncharacterized protein family UPF0029
A9C19_RS01740	COG4585	Histidine kinase
A9C19_RS01745	COG2197	response regulator
A9C19_RS01750	COG1307	EDD domain protein, DegV family
A9C19_RS01760	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
A9C19_RS01770	COG1040	competence protein
A9C19_RS01785	COG3418	PFAM FlgN family protein
A9C19_RS01790	COG4786	Flagellar basal body rod
A9C19_RS01790	COG1256	bacterial-type flagellum assembly
A9C19_RS01795	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A9C19_RS01805	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
A9C19_RS01810	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
A9C19_RS01820	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A9C19_RS01830	COG2003	Belongs to the UPF0758 family
A9C19_RS01845	COG1334	flagellar protein FlaG
A9C19_RS01850	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
A9C19_RS01855	COG1516	flagellar protein fliS
A9C19_RS01875	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
A9C19_RS01880	COG1609	Transcriptional regulator
A9C19_RS01885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A9C19_RS01895	COG1129	ABC transporter
A9C19_RS01900	COG1172	Belongs to the binding-protein-dependent transport system permease family
A9C19_RS01905	COG1879	ABC-type sugar transport system periplasmic component
A9C19_RS01910	COG0653	protein targeting
A9C19_RS01915	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
A9C19_RS01920	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A9C19_RS01925	COG2010	Cytochrome c
A9C19_RS01930	COG2884	Cell division ATP-binding protein ftsE
A9C19_RS01935	COG2177	Part of the ABC transporter FtsEX involved in
A9C19_RS01940	COG0739	heme binding
A9C19_RS01945	COG3409	Peptidoglycan-binding domain 1 protein
A9C19_RS01945	COG0793	Belongs to the peptidase S41A family
A9C19_RS01955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A9C19_RS01960	COG0024	Methionine aminopeptidase
A9C19_RS01965	COG1937	Protein conserved in bacteria
A9C19_RS01970	COG0425	Belongs to the sulfur carrier protein TusA family
A9C19_RS01975	COG2210	Belongs to the sulfur carrier protein TusA family
A9C19_RS01980	COG1054	Belongs to the UPF0176 family
A9C19_RS01990	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A9C19_RS01990	COG0425	Belongs to the sulfur carrier protein TusA family
A9C19_RS01995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A9C19_RS01995	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A9C19_RS02000	COG0425	Belongs to the sulfur carrier protein TusA family
A9C19_RS02005	COG0730	response to heat
A9C19_RS02010	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
A9C19_RS02010	COG2213	PTS system mannitol-specific
A9C19_RS02015	COG3711	transcriptional antiterminator
A9C19_RS02020	COG0246	Mannitol dehydrogenase
A9C19_RS02030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A9C19_RS02035	COG1482	cell wall glycoprotein biosynthetic process
A9C19_RS02045	COG1309	transcriptional regulator
A9C19_RS02050	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
A9C19_RS02055	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A9C19_RS02055	COG0574	Belongs to the PEP-utilizing enzyme family
A9C19_RS02060	COG1392	Phosphate transport regulator
A9C19_RS02065	COG0306	phosphate transporter
A9C19_RS02070	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
A9C19_RS02075	COG0456	acetyltransferase
A9C19_RS02080	COG4897	Protein conserved in bacteria
A9C19_RS02085	COG0556	nucleotide-excision repair
A9C19_RS02090	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A9C19_RS02095	COG1595	DNA-templated transcription, initiation
A9C19_RS02110	COG3595	metallopeptidase activity
A9C19_RS02115	COG1983	PspC domain protein
A9C19_RS02120	COG1950	PFAM Membrane protein of
A9C19_RS02125	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
A9C19_RS02135	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
A9C19_RS02140	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
A9C19_RS02145	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
A9C19_RS02150	COG0546	phosphoglycolate phosphatase activity
A9C19_RS02155	COG0110	maltose O-acetyltransferase activity
A9C19_RS02160	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
A9C19_RS02170	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
A9C19_RS02175	COG0131	Imidazoleglycerol-phosphate dehydratase
A9C19_RS02180	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
A9C19_RS02185	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
A9C19_RS02190	COG0107	imidazoleglycerol-phosphate synthase activity
A9C19_RS02195	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
A9C19_RS02195	COG0140	phosphoribosyl-ATP diphosphatase activity
A9C19_RS02215	COG0457	Tetratricopeptide repeat
A9C19_RS02225	COG0492	ferredoxin-NADP+ reductase activity
A9C19_RS02230	COG1051	belongs to the nudix hydrolase family
A9C19_RS02240	COG0391	Required for morphogenesis under gluconeogenic growth conditions
A9C19_RS02245	COG1481	regulation of sporulation
A9C19_RS02250	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A9C19_RS02270	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
A9C19_RS02285	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A9C19_RS02305	COG0148	phosphopyruvate hydratase activity
A9C19_RS02320	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A9C19_RS02325	COG1647	Serine aminopeptidase, S33
A9C19_RS02330	COG0557	exoribonuclease II activity
A9C19_RS02335	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
A9C19_RS02375	COG1309	transcriptional regulator
A9C19_RS02380	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A9C19_RS02400	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
A9C19_RS02400	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
A9C19_RS02410	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
A9C19_RS02415	COG1609	Transcriptional regulator
A9C19_RS02420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A9C19_RS02435	COG3773	Cell wall hydrolase
A9C19_RS02440	COG1522	sequence-specific DNA binding
A9C19_RS02445	COG0697	spore germination
A9C19_RS02450	COG0519	Catalyzes the synthesis of GMP from XMP
A9C19_RS02455	COG0860	N-Acetylmuramoyl-L-alanine amidase
A9C19_RS02460	COG1595	DNA-templated transcription, initiation
A9C19_RS02475	COG0561	phosphatase activity
A9C19_RS02525	COG3706	GGDEF domain
A9C19_RS02530	COG0640	Transcriptional regulator
A9C19_RS02535	COG1012	belongs to the aldehyde dehydrogenase family
A9C19_RS02540	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
A9C19_RS02545	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
A9C19_RS02550	COG2267	carboxylic ester hydrolase activity
A9C19_RS02560	COG2201	protein-glutamate methylesterase activity
A9C19_RS02570	COG0791	NLP P60 protein
A9C19_RS02570	COG3883	PFAM NLP P60 protein
A9C19_RS02580	COG0523	cobalamin synthesis protein
A9C19_RS02585	COG0267	Belongs to the bacterial ribosomal protein bL33 family
A9C19_RS02600	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A9C19_RS02605	COG1122	ATPase activity
A9C19_RS02615	COG0205	6-phosphofructokinase activity
A9C19_RS02620	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A9C19_RS02630	COG0693	protein deglycase activity
A9C19_RS02640	COG5002	protein histidine kinase activity
A9C19_RS02645	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A9C19_RS02650	COG0840	transmembrane signaling receptor activity
A9C19_RS02660	COG0456	acetyltransferase
A9C19_RS02670	COG1388	LysM domain
A9C19_RS02670	COG0791	NLP P60 protein
A9C19_RS02675	COG1388	LysM domain
A9C19_RS02675	COG0791	NLP P60 protein
A9C19_RS02680	COG1705	Flagellar rod assembly protein muramidase FlgJ
A9C19_RS02680	COG1388	LysM domain
A9C19_RS02690	COG2814	Major facilitator Superfamily
A9C19_RS02700	COG2608	mercury ion transmembrane transporter activity
A9C19_RS02705	COG4682	membrane
A9C19_RS02710	COG1695	Transcriptional regulator
A9C19_RS02735	COG1193	negative regulation of DNA recombination
A9C19_RS02740	COG0446	pyridine nucleotide-disulphide oxidoreductase
A9C19_RS02745	COG0114	fumarate hydratase activity
A9C19_RS02750	COG2770	Histidine kinase
A9C19_RS02750	COG2205	protein histidine kinase activity
A9C19_RS02755	COG0745	RESPONSE REGULATOR receiver
A9C19_RS02760	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A9C19_RS02770	COG1136	(ABC) transporter
A9C19_RS02770	COG0577	efflux transmembrane transporter activity
A9C19_RS02785	COG4191	Histidine kinase
A9C19_RS02790	COG3546	catalase activity
A9C19_RS02805	COG2076	Multidrug Resistance protein
A9C19_RS02810	COG2076	Multidrug Resistance protein
A9C19_RS02820	COG1686	Belongs to the peptidase S11 family
A9C19_RS02830	COG1301	dicarboxylic acid transport
A9C19_RS02835	COG0569	domain protein
A9C19_RS02840	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A9C19_RS02860	COG0506	proline dehydrogenase activity
A9C19_RS02870	COG1250	3-hydroxyacyl-CoA dehydrogenase
A9C19_RS02870	COG1024	Enoyl-CoA hydratase
A9C19_RS02875	COG0183	Belongs to the thiolase family
A9C19_RS02880	COG1960	acyl-CoA dehydrogenase activity
A9C19_RS02885	COG1393	Belongs to the ArsC family
A9C19_RS02890	COG0509	glycine decarboxylation via glycine cleavage system
A9C19_RS02900	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
A9C19_RS02905	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A9C19_RS02915	COG2873	o-acetylhomoserine
A9C19_RS02920	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A9C19_RS02925	COG2011	ABC-type metal ion transport system permease component
A9C19_RS02930	COG1464	Belongs to the NlpA lipoprotein family
A9C19_RS02935	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A9C19_RS02940	COG0396	ATPase activity
A9C19_RS02945	COG0719	Fe-S assembly protein
A9C19_RS02950	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A9C19_RS02955	COG0822	iron-sulfur transferase activity
A9C19_RS02960	COG0719	Fe-S assembly protein
A9C19_RS02990	COG1801	Protein of unknown function DUF72
A9C19_RS02995	COG0730	response to heat
A9C19_RS03000	COG0737	Belongs to the 5'-nucleotidase family
A9C19_RS03005	COG3377	Domain of unknown function (DUF1805)
A9C19_RS03010	COG1757	Na H antiporter
A9C19_RS03015	COG0733	neurotransmitter:sodium symporter activity
A9C19_RS03025	COG0739	heme binding
A9C19_RS03030	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
A9C19_RS03040	COG4470	Protein conserved in bacteria
A9C19_RS03055	COG3300	MHYT domain
A9C19_RS03055	COG5001	Diguanylate cyclase
A9C19_RS03060	COG2445	Protein of unknown function DUF86
A9C19_RS03065	COG0647	UMP catabolic process
A9C19_RS03070	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
A9C19_RS03075	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A9C19_RS03080	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A9C19_RS03085	COG0460	homoserine dehydrogenase
A9C19_RS03090	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A9C19_RS03095	COG0083	homoserine kinase activity
A9C19_RS03100	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
A9C19_RS03105	COG4837	Protein of unknown function (DUF1462)
A9C19_RS03110	COG1252	NADH dehydrogenase
A9C19_RS03120	COG2356	endonuclease I
A9C19_RS03185	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
A9C19_RS03190	COG0316	Belongs to the HesB IscA family
A9C19_RS03195	COG1252	NADH dehydrogenase
A9C19_RS03205	COG3584	3D domain protein
A9C19_RS03215	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
A9C19_RS03220	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
A9C19_RS03235	COG2056	Na+-H+ antiporter family
A9C19_RS03245	COG1268	BioY protein
A9C19_RS03250	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
A9C19_RS03270	COG1764	response to oxidative stress
A9C19_RS03275	COG1846	Transcriptional regulator
A9C19_RS03280	COG0686	Belongs to the AlaDH PNT family
A9C19_RS03285	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
A9C19_RS03285	COG2508	Transcriptional regulator
A9C19_RS03290	COG1028	Short-chain dehydrogenase reductase Sdr
A9C19_RS03295	COG3290	protein histidine kinase activity
A9C19_RS03300	COG1418	mRNA catabolic process
A9C19_RS03310	COG0789	Transcriptional regulator
A9C19_RS03315	COG2738	Putative neutral zinc metallopeptidase
A9C19_RS03320	COG1253	flavin adenine dinucleotide binding
A9C19_RS03325	COG0628	permease
A9C19_RS03340	COG2368	4-hydroxyphenylacetate
A9C19_RS03345	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
A9C19_RS03350	COG0861	Integral membrane protein TerC family
A9C19_RS03365	COG0142	geranyltranstransferase activity
A9C19_RS03375	COG4585	Histidine kinase
A9C19_RS03380	COG2197	response regulator
A9C19_RS03385	COG2050	protein possibly involved in aromatic compounds catabolism
A9C19_RS03390	COG2059	Chromate
A9C19_RS03395	COG2059	Chromate
A9C19_RS03400	COG1320	monovalent cation:proton antiporter activity
A9C19_RS03405	COG2212	antiporter activity
A9C19_RS03410	COG1863	multisubunit Na H antiporter MnhE subunit
A9C19_RS03415	COG0651	ATP synthesis coupled electron transport
A9C19_RS03420	COG1006	Multisubunit Na H antiporter MnhC subunit
A9C19_RS03425	COG2111	Na H antiporter
A9C19_RS03430	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A9C19_RS03430	COG2111	Na H antiporter
A9C19_RS03445	COG3011	Protein conserved in bacteria
A9C19_RS03450	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A9C19_RS03455	COG5018	Exonuclease
A9C19_RS03470	COG2032	superoxide dismutase activity
A9C19_RS03475	COG2205	protein histidine kinase activity
A9C19_RS03480	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
A9C19_RS03490	COG2267	carboxylic ester hydrolase activity
A9C19_RS03495	COG1522	sequence-specific DNA binding
A9C19_RS03500	COG0436	Aminotransferase
A9C19_RS03505	COG1098	S1 RNA binding domain
A9C19_RS03515	COG2155	Conserved Protein
A9C19_RS03520	COG1979	alcohol dehydrogenase
A9C19_RS03525	COG0166	Belongs to the GPI family
A9C19_RS03535	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A9C19_RS03545	COG2738	Putative neutral zinc metallopeptidase
A9C19_RS03570	COG0745	RESPONSE REGULATOR receiver
A9C19_RS03575	COG5002	protein histidine kinase activity
A9C19_RS03580	COG0432	Pfam Uncharacterised protein family UPF0047
A9C19_RS03600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A9C19_RS03620	COG1846	Transcriptional regulator
A9C19_RS03640	COG1278	Cold shock
A9C19_RS03645	COG0745	RESPONSE REGULATOR receiver
A9C19_RS03650	COG5002	protein histidine kinase activity
A9C19_RS03650	COG3850	Histidine kinase
A9C19_RS03655	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A9C19_RS03665	COG2264	protein methyltransferase activity
A9C19_RS03675	COG1227	inorganic diphosphatase activity
A9C19_RS03685	COG1309	transcriptional regulator
A9C19_RS03690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A9C19_RS03710	COG2357	RelA SpoT domain protein
A9C19_RS03720	COG2197	response regulator
A9C19_RS03725	COG4585	Histidine kinase
A9C19_RS03730	COG3239	Fatty acid desaturase
A9C19_RS03735	COG1494	fructose-1,6-bisphosphatase
A9C19_RS03740	COG0861	Integral membrane protein TerC family
A9C19_RS03755	COG5522	Integral membrane protein (intg_mem_TP0381)
A9C19_RS03760	COG1388	LysM domain
A9C19_RS03760	COG3584	3D domain protein
A9C19_RS03765	COG0326	Molecular chaperone. Has ATPase activity
A9C19_RS03770	COG1366	Belongs to the anti-sigma-factor antagonist family
A9C19_RS03785	COG0697	spore germination
A9C19_RS03790	COG2843	Capsule synthesis protein
A9C19_RS03795	COG2814	Major facilitator Superfamily
A9C19_RS03800	COG1309	transcriptional regulator
A9C19_RS03805	COG1349	DNA-binding transcription factor activity
A9C19_RS03815	COG4209	transmembrane transport
A9C19_RS03820	COG0395	ABC-type sugar transport system, permease component
A9C19_RS03830	COG2201	protein-glutamate methylesterase activity
A9C19_RS03835	COG2972	Histidine kinase
A9C19_RS03840	COG1028	Short-chain dehydrogenase reductase Sdr
A9C19_RS03870	COG4876	unkown
A9C19_RS03895	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
A9C19_RS03905	COG2318	DinB family
A9C19_RS03925	COG3859	Proton-coupled thiamine transporter YuaJ
A9C19_RS04060	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
A9C19_RS04065	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
A9C19_RS04070	COG0297	glycogen (starch) synthase activity
A9C19_RS04075	COG0058	SHG alpha-glucan phosphorylase activity
A9C19_RS04090	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A9C19_RS04095	COG1575	Belongs to the MenA family. Type 1 subfamily
A9C19_RS04100	COG1169	isochorismate synthase
A9C19_RS04105	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
A9C19_RS04110	COG0596	Alpha beta hydrolase
A9C19_RS04115	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
A9C19_RS04120	COG0318	PFAM AMP-dependent synthetase and ligase
A9C19_RS04125	COG4948	Mandelate Racemase Muconate Lactonizing
A9C19_RS04130	COG0803	Belongs to the bacterial solute-binding protein 9 family
A9C19_RS04135	COG1121	(ABC) transporter
A9C19_RS04140	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A9C19_RS04140	COG1321	iron dependent repressor
A9C19_RS04145	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A9C19_RS04155	COG1294	oxidase, subunit
A9C19_RS04160	COG1271	oxidase subunit
A9C19_RS04175	COG0288	reversible hydration of carbon dioxide
A9C19_RS04180	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
A9C19_RS04185	COG1854	S-ribosylhomocysteine lyase activity
A9C19_RS04190	COG1469	GTP cyclohydrolase I activity
A9C19_RS04195	COG0701	Predicted permease
A9C19_RS04210	COG0783	Belongs to the Dps family
A9C19_RS04225	COG0494	nUDIX hydrolase
A9C19_RS04230	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A9C19_RS04235	COG1116	anion transmembrane transporter activity
A9C19_RS04240	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A9C19_RS04245	COG1506	peptidase
A9C19_RS04255	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
A9C19_RS04260	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
A9C19_RS04270	COG5002	protein histidine kinase activity
A9C19_RS04275	COG0745	RESPONSE REGULATOR receiver
A9C19_RS04305	COG0714	Associated with various cellular activities
A9C19_RS04320	COG1714	RDD family
A9C19_RS04325	COG0438	transferase activity, transferring glycosyl groups
A9C19_RS04330	COG0671	phosphoesterase, PA-phosphatase related
A9C19_RS04335	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
A9C19_RS04340	COG2267	carboxylic ester hydrolase activity
A9C19_RS04350	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
A9C19_RS04355	COG1242	4 iron, 4 sulfur cluster binding
A9C19_RS04370	COG1136	(ABC) transporter
A9C19_RS04375	COG0577	efflux transmembrane transporter activity
A9C19_RS04385	COG2175	clavaminate synthase activity
A9C19_RS04390	COG1378	Sugar-specific transcriptional regulator TrmB
A9C19_RS04400	COG2814	Major facilitator Superfamily
A9C19_RS04405	COG3829	transcription factor binding
A9C19_RS04405	COG3290	protein histidine kinase activity
A9C19_RS04410	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
A9C19_RS04415	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
A9C19_RS04420	COG2610	gluconate transmembrane transporter activity
A9C19_RS04425	COG1028	Short-chain dehydrogenase reductase Sdr
A9C19_RS04430	COG0495	leucyl-tRNA aminoacylation
A9C19_RS04435	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A9C19_RS04445	COG2081	HI0933 family
A9C19_RS04450	COG2244	polysaccharide biosynthetic process
A9C19_RS04455	COG1187	pseudouridine synthase activity
A9C19_RS04460	COG1349	DNA-binding transcription factor activity
A9C19_RS04465	COG1131	(ABC) transporter
A9C19_RS04470	COG4473	ABC transporter
A9C19_RS04475	COG0024	Methionine aminopeptidase
A9C19_RS04480	COG2252	PERMEase
A9C19_RS04485	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A9C19_RS04495	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A9C19_RS04505	COG1380	Effector of murein hydrolase LrgA
A9C19_RS04510	COG1346	cytolysis
A9C19_RS04520	COG1597	lipid kinase activity
A9C19_RS04525	COG1523	belongs to the glycosyl hydrolase 13 family
A9C19_RS04530	COG0510	thiamine kinase activity
A9C19_RS04540	COG0220	tRNA (guanine-N7-)-methyltransferase activity
A9C19_RS04545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A9C19_RS04550	COG5584	Small secreted protein
A9C19_RS04555	COG1363	Peptidase, m42
A9C19_RS04560	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
A9C19_RS04575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A9C19_RS04580	COG4848	Belongs to the UPF0354 family
A9C19_RS04585	COG1674	ftsk spoiiie
A9C19_RS04595	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
A9C19_RS04600	COG2309	aminopeptidase activity
A9C19_RS04605	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
A9C19_RS04610	COG4980	gas vesicle protein
A9C19_RS04615	COG3118	belongs to the thioredoxin family
A9C19_RS04620	COG0849	cell division
A9C19_RS04625	COG1605	Chorismate mutase
A9C19_RS04625	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
A9C19_RS04630	COG1609	Transcriptional regulator
A9C19_RS04635	COG0123	including yeast histone deacetylase and acetoin utilization protein
A9C19_RS04640	COG0517	IMP dehydrogenase activity
A9C19_RS04645	COG0454	-acetyltransferase
A9C19_RS04650	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A9C19_RS04660	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
A9C19_RS04670	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
A9C19_RS04675	COG2203	Gaf domain
A9C19_RS04675	COG2199	diguanylate cyclase activity
A9C19_RS04680	COG1956	GAF domain-containing protein
A9C19_RS04685	COG1309	transcriptional regulator
A9C19_RS04690	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A9C19_RS04695	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
A9C19_RS04700	COG1104	cysteine desulfurase activity
A9C19_RS04705	COG0301	tRNA thio-modification
A9C19_RS04715	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A9C19_RS04720	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A9C19_RS04725	COG0616	signal peptide processing
A9C19_RS04730	COG1714	RDD family
A9C19_RS04740	COG3874	Sporulation protein YtfJ
A9C19_RS04745	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
A9C19_RS04750	COG0827	DNA restriction-modification system
A9C19_RS04755	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
A9C19_RS04765	COG0521	Mo-molybdopterin cofactor biosynthetic process
A9C19_RS04770	COG2801	Transposase and inactivated derivatives
A9C19_RS04785	COG0137	argininosuccinate synthase activity
A9C19_RS04790	COG0165	Argininosuccinate lyase
A9C19_RS04795	COG1028	Short-chain dehydrogenase reductase Sdr
A9C19_RS04805	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A9C19_RS04815	COG4109	DRTGG domain
A9C19_RS04825	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
A9C19_RS04845	COG0587	DNA-directed DNA polymerase activity
A9C19_RS04850	COG0281	malic enzyme
A9C19_RS04855	COG1725	Transcriptional regulator
A9C19_RS04860	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
A9C19_RS04865	COG0825	malonyl-CoA metabolic process
A9C19_RS04870	COG0205	6-phosphofructokinase activity
A9C19_RS04880	COG3030	protein affecting phage T7 exclusion by the F plasmid
A9C19_RS04885	COG0628	permease
A9C19_RS04890	COG2707	UPF0756 membrane protein
A9C19_RS04895	COG0372	Belongs to the citrate synthase family
A9C19_RS04900	COG0538	isocitrate dehydrogenase activity
A9C19_RS04905	COG0039	L-malate dehydrogenase activity
A9C19_RS04915	COG0745	RESPONSE REGULATOR receiver
A9C19_RS04920	COG5002	protein histidine kinase activity
A9C19_RS04925	COG0330	HflC and HflK could
A9C19_RS04930	COG0330	HflC and HflK could
A9C19_RS04935	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A9C19_RS04935	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A9C19_RS04940	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
A9C19_RS04945	COG1971	Probably functions as a manganese efflux pump
A9C19_RS04955	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A9C19_RS04960	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
A9C19_RS04970	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
A9C19_RS04975	COG3611	Membrane attachment protein
A9C19_RS04980	COG1484	DNA-dependent DNA replication
A9C19_RS04990	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A9C19_RS05000	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
A9C19_RS05010	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
A9C19_RS05015	COG3326	Membrane
A9C19_RS05035	COG1363	Peptidase, m42
A9C19_RS05045	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A9C19_RS05050	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
A9C19_RS05055	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A9C19_RS05055	COG0072	phenylalanine-tRNA ligase activity
A9C19_RS05060	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
A9C19_RS05065	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
A9C19_RS05070	COG1286	toxin biosynthetic process
A9C19_RS05075	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A9C19_RS05075	COG1796	DNA polymerase
A9C19_RS05080	COG1193	negative regulation of DNA recombination
A9C19_RS05085	COG3766	membrane
A9C19_RS05090	COG0318	PFAM AMP-dependent synthetase and ligase
A9C19_RS05095	COG1309	transcriptional regulator
A9C19_RS05100	COG1024	Enoyl-CoA hydratase
A9C19_RS05105	COG2086	electron transfer activity
A9C19_RS05110	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
A9C19_RS05115	COG3118	belongs to the thioredoxin family
A9C19_RS05120	COG0322	excinuclease ABC activity
A9C19_RS05135	COG1719	4-vinyl reductase, 4VR
A9C19_RS05140	COG2009	succinate dehydrogenase
A9C19_RS05145	COG1053	succinate dehydrogenase
A9C19_RS05150	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A9C19_RS05155	COG2197	response regulator
A9C19_RS05165	COG2318	DinB family
A9C19_RS05175	COG3344	reverse transcriptase
A9C19_RS05225	COG3655	Transcriptional regulator
A9C19_RS05235	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
A9C19_RS05275	COG0497	DNA recombination
A9C19_RS05290	COG2197	response regulator
A9C19_RS05295	COG1846	Transcriptional regulator
A9C19_RS05305	COG5401	PFAM Sporulation and spore germination
A9C19_RS05310	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
A9C19_RS05315	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
A9C19_RS05320	COG0622	Phosphoesterase
A9C19_RS05330	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A9C19_RS05335	COG0028	Belongs to the TPP enzyme family
A9C19_RS05340	COG0440	acetolactate synthase activity
A9C19_RS05345	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
A9C19_RS05350	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A9C19_RS05355	COG0473	3-isopropylmalate dehydrogenase activity
A9C19_RS05360	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
A9C19_RS05365	COG0066	3-isopropylmalate dehydratase activity
A9C19_RS05370	COG0457	Tetratricopeptide repeat
A9C19_RS05370	COG1477	protein flavinylation
A9C19_RS05375	COG0544	peptidyl-prolyl cis-trans isomerase activity
A9C19_RS05380	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
A9C19_RS05390	COG0470	DNA polymerase III
A9C19_RS05390	COG1067	ATP-dependent peptidase activity
A9C19_RS05395	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
A9C19_RS05415	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A9C19_RS05420	COG0181	hydroxymethylbilane synthase activity
A9C19_RS05425	COG1587	Uroporphyrinogen-III synthase
A9C19_RS05430	COG0113	porphobilinogen synthase activity
A9C19_RS05435	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
A9C19_RS05440	COG0697	spore germination
A9C19_RS05455	COG1388	LysM domain
A9C19_RS05455	COG1388	LysM domain
A9C19_RS05460	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A9C19_RS05470	COG0525	valine-tRNA ligase activity
A9C19_RS05475	COG0285	dihydrofolate synthase activity
A9C19_RS05520	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A9C19_RS05530	COG1459	type II secretion system
A9C19_RS05540	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
A9C19_RS05565	COG0424	maF-like protein
A9C19_RS05570	COG2003	Belongs to the UPF0758 family
A9C19_RS05580	COG2003	Belongs to the UPF0758 family
A9C19_RS05585	COG1077	Cell shape determining protein MreB Mrl
A9C19_RS05590	COG1792	Involved in formation and maintenance of cell shape
A9C19_RS05595	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
A9C19_RS05600	COG0850	regulation of cytokinetic process
A9C19_RS05605	COG2894	cell division
A9C19_RS05610	COG0739	heme binding
A9C19_RS05615	COG1994	Peptidase M50
A9C19_RS05620	COG1530	ribonuclease E activity
A9C19_RS05625	COG0261	This protein binds to 23S rRNA in the presence of protein L20
A9C19_RS05630	COG2868	ribosomal protein
A9C19_RS05640	COG3290	protein histidine kinase activity
A9C19_RS05650	COG4492	Belongs to the UPF0735 family
A9C19_RS05655	COG0077	Prephenate dehydratase
A9C19_RS05660	COG1827	regulation of RNA biosynthetic process
A9C19_RS05665	COG1104	cysteine desulfurase activity
A9C19_RS05670	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
A9C19_RS05675	COG0157	Belongs to the NadC ModD family
A9C19_RS05680	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
A9C19_RS05685	COG1388	LysM domain
A9C19_RS05700	COG0632	four-way junction helicase activity
A9C19_RS05705	COG2255	four-way junction helicase activity
A9C19_RS05725	COG1862	Preprotein translocase
A9C19_RS05740	COG2323	membrane
A9C19_RS05745	COG2244	polysaccharide biosynthetic process
A9C19_RS05755	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A9C19_RS05755	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A9C19_RS05760	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A9C19_RS05765	COG5416	Lipopolysaccharide assembly protein A domain
A9C19_RS05770	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
A9C19_RS05770	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A9C19_RS05775	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A9C19_RS05780	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A9C19_RS05785	COG1490	D-aminoacyl-tRNA deacylase activity
A9C19_RS05790	COG4991	sh3 domain protein
A9C19_RS05790	COG3103	Sh3 type 3 domain protein
A9C19_RS05790	COG0860	N-Acetylmuramoyl-L-alanine amidase
A9C19_RS05800	COG0124	histidyl-tRNA synthetase
A9C19_RS05805	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
A9C19_RS05815	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
A9C19_RS05825	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A9C19_RS05830	COG2364	Membrane
A9C19_RS05835	COG1959	2 iron, 2 sulfur cluster binding
A9C19_RS05840	COG1104	cysteine desulfurase activity
A9C19_RS05845	COG0482	sulfurtransferase activity
A9C19_RS05850	COG0457	Tetratricopeptide repeat
A9C19_RS05855	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A9C19_RS05875	COG0189	ligase activity
A9C19_RS05900	COG0628	permease
A9C19_RS05905	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A9C19_RS05910	COG4472	Bacterial protein of unknown function (DUF965)
A9C19_RS05920	COG3906	Belongs to the UPF0473 family
A9C19_RS05925	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A9C19_RS05930	COG4122	O-methyltransferase activity
A9C19_RS05935	COG0826	peptidase U32
A9C19_RS05940	COG0826	peptidase U32
A9C19_RS05945	COG0572	uridine kinase
A9C19_RS05950	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A9C19_RS05955	COG0768	penicillin binding
A9C19_RS05970	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A9C19_RS05995	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
A9C19_RS06000	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
A9C19_RS06010	COG1534	Rna-binding protein
A9C19_RS06015	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
A9C19_RS06020	COG1713	HD superfamily hydrolase involved in NAD metabolism
A9C19_RS06025	COG0799	negative regulation of ribosome biogenesis
A9C19_RS06030	COG2226	methyltransferase
A9C19_RS06035	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A9C19_RS06040	COG1555	photosystem II stabilization
A9C19_RS06040	COG1596	polysaccharide export
A9C19_RS06045	COG2131	deaminase
A9C19_RS06050	COG0658	competence protein
A9C19_RS06050	COG2333	competence protein COMEC
A9C19_RS06060	COG1466	dna polymerase III delta subunit
A9C19_RS06065	COG0268	Binds directly to 16S ribosomal RNA
A9C19_RS06070	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
A9C19_RS06075	COG0860	N-Acetylmuramoyl-L-alanine amidase
A9C19_RS06085	COG0481	GTPase activity
A9C19_RS06090	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A9C19_RS06095	COG1420	regulation of RNA biosynthetic process
A9C19_RS06115	COG2264	protein methyltransferase activity
A9C19_RS06120	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A9C19_RS06125	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A9C19_RS06130	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
A9C19_RS06135	COG0828	Belongs to the bacterial ribosomal protein bS21 family
A9C19_RS06140	COG1610	YqeY-like protein
A9C19_RS06145	COG1030	water channel activity
A9C19_RS06150	COG4864	UPF0365 protein
A9C19_RS06170	COG1702	phosphate starvation-inducible protein PhoH
A9C19_RS06175	COG1480	7TM receptor with intracellular HD hydrolase
A9C19_RS06180	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
A9C19_RS06185	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
A9C19_RS06190	COG0295	cytidine deaminase activity
A9C19_RS06195	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
A9C19_RS06205	COG1381	Involved in DNA repair and RecF pathway recombination
A9C19_RS06210	COG0752	glycyl-tRNA synthetase alpha subunit
A9C19_RS06215	COG0751	glycine-tRNA ligase activity
A9C19_RS06220	COG0517	IMP dehydrogenase activity
A9C19_RS06225	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
A9C19_RS06230	COG1671	Belongs to the UPF0178 family
A9C19_RS06235	COG0358	DNA primase activity
A9C19_RS06240	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A9C19_RS06250	COG2010	Cytochrome c
A9C19_RS06255	COG2384	SAM-dependent methyltransferase
A9C19_RS06260	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A9C19_RS06265	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
A9C19_RS06275	COG0513	Belongs to the DEAD box helicase family
A9C19_RS06280	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
A9C19_RS06290	COG1121	(ABC) transporter
A9C19_RS06295	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A9C19_RS06300	COG0735	belongs to the Fur family
A9C19_RS06305	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
A9C19_RS06310	COG4709	membrane
A9C19_RS06320	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
A9C19_RS06330	COG0840	transmembrane signaling receptor activity
A9C19_RS06335	COG5521	maltodextrose utilization protein MalA
A9C19_RS06340	COG1283	sodium-dependent phosphate transmembrane transporter activity
A9C19_RS06345	COG2839	Protein conserved in bacteria
A9C19_RS06355	COG0477	Major facilitator Superfamily
A9C19_RS06360	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A9C19_RS06365	COG0573	inorganic phosphate transmembrane transporter activity
A9C19_RS06370	COG0581	inorganic phosphate transmembrane transporter activity
A9C19_RS06380	COG0704	Plays a role in the regulation of phosphate uptake
A9C19_RS06410	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A9C19_RS06420	COG0457	Tetratricopeptide repeat
A9C19_RS06420	COG0705	Rhomboid family
A9C19_RS06430	COG0697	spore germination
A9C19_RS06435	COG1966	Carbon starvation protein
A9C19_RS06445	COG1940	carbohydrate kinase activity
A9C19_RS06450	COG1368	sulfuric ester hydrolase activity
A9C19_RS06465	COG0011	TIGRFAM Protein of
A9C19_RS06475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A9C19_RS06485	COG1393	Belongs to the ArsC family
A9C19_RS06495	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A9C19_RS06500	COG1459	type II secretion system
A9C19_RS06505	COG4537	Required for transformation and DNA binding
A9C19_RS06510	COG4970	Tfp pilus assembly protein FimT
A9C19_RS06540	COG1476	TRANSCRIPTIONal
A9C19_RS06560	COG1396	sequence-specific DNA binding
A9C19_RS06585	COG0681	Belongs to the peptidase S26 family
A9C19_RS06605	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A9C19_RS06610	COG0404	The glycine cleavage system catalyzes the degradation of glycine
A9C19_RS06615	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A9C19_RS06630	COG4536	flavin adenine dinucleotide binding
A9C19_RS06640	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A9C19_RS06645	COG0095	Lipoate-protein ligase
A9C19_RS06665	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A9C19_RS06675	COG1321	iron dependent repressor
A9C19_RS06685	COG0444	Belongs to the ABC transporter superfamily
A9C19_RS06690	COG4608	Belongs to the ABC transporter superfamily
A9C19_RS06695	COG0747	negative chemotaxis
A9C19_RS06700	COG0601	transmembrane transport
A9C19_RS06705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A9C19_RS06710	COG1752	Esterase of the alpha-beta hydrolase superfamily
A9C19_RS06720	COG3872	metal-dependent enzyme
A9C19_RS06730	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
A9C19_RS06735	COG0006	proline dipeptidase activity
A9C19_RS06740	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
A9C19_RS06755	COG3854	ATPases associated with a variety of cellular activities
A9C19_RS06795	COG0511	ligase activity, forming carbon-carbon bonds
A9C19_RS06800	COG0439	Biotin carboxylase
A9C19_RS06805	COG1302	Protein conserved in bacteria
A9C19_RS06810	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A9C19_RS06815	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
A9C19_RS06820	COG1570	exodeoxyribonuclease VII activity
A9C19_RS06825	COG1722	exodeoxyribonuclease VII activity
A9C19_RS06830	COG0142	geranyltranstransferase activity
A9C19_RS06835	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
A9C19_RS06840	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
A9C19_RS06850	COG0497	DNA recombination
A9C19_RS06855	COG0750	zinc metalloprotease
A9C19_RS06865	COG0745	RESPONSE REGULATOR receiver
A9C19_RS06875	COG3093	addiction module antidote protein HigA
A9C19_RS06890	COG3829	transcription factor binding
A9C19_RS06890	COG3290	protein histidine kinase activity
A9C19_RS06895	COG0280	phosphate acetyltransferase
A9C19_RS06910	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A9C19_RS06915	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A9C19_RS06920	COG0022	dehydrogenase e1 component
A9C19_RS06925	COG0508	dehydrogenase complex catalyzes the overall conversion of
A9C19_RS06930	COG1597	lipid kinase activity
A9C19_RS06935	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A9C19_RS06940	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A9C19_RS06940	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A9C19_RS06945	COG1703	isobutyryl-CoA mutase activity
A9C19_RS06955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A9C19_RS06960	COG0765	amino acid transport
A9C19_RS06965	COG1126	abc transporter atp-binding protein
A9C19_RS06970	COG4129	membrane
A9C19_RS06975	COG1376	ErfK ybiS ycfS ynhG family protein
A9C19_RS06980	COG0346	lactoylglutathione lyase activity
A9C19_RS06985	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A9C19_RS06990	COG2195	Cleaves the N-terminal amino acid of tripeptides
A9C19_RS06995	COG2340	Cysteine-rich secretory protein family
A9C19_RS07065	COG0835	chemotaxis
A9C19_RS07095	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A9C19_RS07100	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
A9C19_RS07105	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
A9C19_RS07110	COG1234	tRNA 3'-trailer cleavage
A9C19_RS07115	COG0477	Major facilitator Superfamily
A9C19_RS07120	COG1902	pentaerythritol trinitrate reductase activity
A9C19_RS07125	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A9C19_RS07130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A9C19_RS07135	COG0300	oxidoreductase activity
A9C19_RS07160	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A9C19_RS07165	COG2755	lipolytic protein G-D-S-L family
A9C19_RS07180	COG4918	Iron-sulphur cluster biosynthesis
A9C19_RS07195	COG1073	alpha beta
A9C19_RS07205	COG0667	Aldo Keto reductase
A9C19_RS07215	COG0494	nUDIX hydrolase
A9C19_RS07220	COG1379	DNA repair
A9C19_RS07230	COG1300	Membrane
A9C19_RS07235	COG0735	belongs to the Fur family
A9C19_RS07245	COG4974	Belongs to the 'phage' integrase family
A9C19_RS07250	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
A9C19_RS07265	COG1686	Belongs to the peptidase S11 family
A9C19_RS07270	COG1366	Belongs to the anti-sigma-factor antagonist family
A9C19_RS07275	COG2172	sigma factor antagonist activity
A9C19_RS07280	COG1191	sigma factor activity
A9C19_RS07300	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A9C19_RS07315	COG0697	spore germination
A9C19_RS07320	COG0019	diaminopimelate decarboxylase activity
A9C19_RS07325	COG4086	secreted protein
A9C19_RS07330	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A9C19_RS07335	COG0307	riboflavin synthase, alpha
A9C19_RS07340	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A9C19_RS07340	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A9C19_RS07350	COG0456	acetyltransferase
A9C19_RS07355	COG1547	Domain of unknown function (DUF309)
A9C19_RS07370	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
A9C19_RS07375	COG1686	Belongs to the peptidase S11 family
A9C19_RS07380	COG2715	membrane protein required for spore maturation
A9C19_RS07385	COG0700	Nucleoside recognition
A9C19_RS07390	COG1187	pseudouridine synthase activity
A9C19_RS07395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A9C19_RS07400	COG1333	cytochrome c biogenesis protein
A9C19_RS07405	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A9C19_RS07410	COG0745	RESPONSE REGULATOR receiver
A9C19_RS07415	COG5002	protein histidine kinase activity
A9C19_RS07420	COG2096	Adenosyltransferase
A9C19_RS07430	COG1595	DNA-templated transcription, initiation
A9C19_RS07440	COG0739	heme binding
A9C19_RS07445	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
A9C19_RS07450	COG1141	Ferredoxin
A9C19_RS07455	COG4955	Helix-turn-helix domain
A9C19_RS07460	COG0514	ATP-dependent DNA helicase (RecQ)
A9C19_RS07465	COG1266	CAAX protease self-immunity
A9C19_RS07470	COG1388	LysM domain
A9C19_RS07480	COG1408	metallophosphoesterase
A9C19_RS07490	COG4862	establishment of competence for transformation
A9C19_RS07495	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A9C19_RS07500	COG0492	ferredoxin-NADP+ reductase activity
A9C19_RS07505	COG0252	asparaginase activity
A9C19_RS07510	COG2339	peptidase activity
A9C19_RS07515	COG3773	Cell wall hydrolase
A9C19_RS07515	COG3409	Peptidoglycan-binding domain 1 protein
A9C19_RS07520	COG2959	enzyme of heme biosynthesis
A9C19_RS07535	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
A9C19_RS07540	COG0204	Acyl-transferase
A9C19_RS07545	COG0539	negative regulation of cytoplasmic translation
A9C19_RS07550	COG1304	FMN binding
A9C19_RS07575	COG1160	GTP binding
A9C19_RS07595	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
A9C19_RS07600	COG0776	regulation of translation
A9C19_RS07605	COG0302	gtp cyclohydrolase
A9C19_RS07615	COG0142	geranyltranstransferase activity
A9C19_RS07625	COG0142	geranyltranstransferase activity
A9C19_RS07630	COG0105	UTP biosynthetic process
A9C19_RS07635	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
A9C19_RS07640	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
A9C19_RS07645	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
A9C19_RS07650	COG4401	Chorismate mutase type I
A9C19_RS07655	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A9C19_RS07660	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A9C19_RS07665	COG0134	indole-3-glycerol-phosphate synthase activity
A9C19_RS07670	COG0135	phosphoribosylanthranilate isomerase activity
A9C19_RS07675	COG0133	tryptophan synthase activity
A9C19_RS07680	COG0159	tryptophan synthase activity
A9C19_RS07695	COG0287	Prephenate dehydrogenase
A9C19_RS07700	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
A9C19_RS07710	COG0457	Tetratricopeptide repeat
A9C19_RS07715	COG5582	Belongs to the UPF0302 family
A9C19_RS07725	COG0723	plastoquinol--plastocyanin reductase activity
A9C19_RS07730	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
A9C19_RS07735	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
A9C19_RS07735	COG2010	Cytochrome c
A9C19_RS07740	COG4347	Protein of unknown function (DUF1405)
A9C19_RS07750	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A9C19_RS07755	COG1694	Mazg nucleotide pyrophosphohydrolase
A9C19_RS07760	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
A9C19_RS07765	COG1803	Methylglyoxal synthase
A9C19_RS07770	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A9C19_RS07775	COG0438	transferase activity, transferring glycosyl groups
A9C19_RS07780	COG0617	tRNA 3'-terminal CCA addition
A9C19_RS07795	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
A9C19_RS07800	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
A9C19_RS07805	COG1199	ATP-dependent helicase activity
A9C19_RS07805	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A9C19_RS07820	COG0017	Asparaginyl-tRNA synthetase
A9C19_RS07825	COG3935	DnaD domain protein
A9C19_RS07830	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A9C19_RS07840	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A9C19_RS07840	COG4499	WXG100 protein secretion system (Wss), protein YukC
A9C19_RS07845	COG3331	DNA recombination
A9C19_RS07870	COG2814	Major facilitator Superfamily
A9C19_RS07875	COG1846	Transcriptional regulator
A9C19_RS07905	COG3344	reverse transcriptase
A9C19_RS07910	COG2190	(PTS) system
A9C19_RS07915	COG1205	dead DEAH box helicase
A9C19_RS07915	COG1111	helicase
A9C19_RS07920	COG3359	exonuclease
A9C19_RS07945	COG0116	Belongs to the methyltransferase superfamily
A9C19_RS07960	COG1199	ATP-dependent helicase activity
A9C19_RS07965	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
A9C19_RS08000	COG3424	synthase
A9C19_RS08005	COG1755	Isoprenylcysteine carboxyl methyltransferase
A9C19_RS08010	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
A9C19_RS08025	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A9C19_RS08045	COG0328	RNA-DNA hybrid ribonuclease activity
A9C19_RS08070	COG1278	Cold shock
A9C19_RS08075	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A9C19_RS08080	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A9C19_RS08085	COG1988	membrane-bound metal-dependent
A9C19_RS08090	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
A9C19_RS08095	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
A9C19_RS08110	COG0386	Belongs to the glutathione peroxidase family
A9C19_RS08120	COG1418	mRNA catabolic process
A9C19_RS08125	COG1388	LysM domain
A9C19_RS08125	COG0791	NLP P60 protein
A9C19_RS08130	COG1413	lyase activity
A9C19_RS08135	COG0129	dihydroxy-acid dehydratase activity
A9C19_RS08145	COG2136	Putative SAM-dependent methyltransferase
A9C19_RS08145	COG2521	methyltransferase
A9C19_RS08165	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
A9C19_RS08170	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A9C19_RS08180	COG1272	protein, Hemolysin III
A9C19_RS08185	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A9C19_RS08205	COG1999	signal sequence binding
A9C19_RS08210	COG2755	lipolytic protein G-D-S-L family
A9C19_RS08215	COG4698	Protein conserved in bacteria
A9C19_RS08225	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A9C19_RS08245	COG1846	Transcriptional regulator
A9C19_RS08250	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A9C19_RS08250	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A9C19_RS08255	COG0346	lactoylglutathione lyase activity
A9C19_RS08265	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
A9C19_RS08270	COG1012	belongs to the aldehyde dehydrogenase family
A9C19_RS08275	COG4479	Belongs to the UPF0346 family
A9C19_RS08310	COG4326	sporulation control protein
A9C19_RS08325	COG1253	flavin adenine dinucleotide binding
A9C19_RS08340	COG0789	Transcriptional regulator
A9C19_RS08345	COG0671	phosphoesterase, PA-phosphatase related
A9C19_RS08360	COG1876	peptidase activity
A9C19_RS08365	COG3663	DNA glycosylase
A9C19_RS08375	COG2226	methyltransferase
A9C19_RS08390	COG0793	Belongs to the peptidase S41A family
A9C19_RS08390	COG3409	Peptidoglycan-binding domain 1 protein
A9C19_RS08395	COG0778	Nitroreductase
A9C19_RS08400	COG1733	regulation of RNA biosynthetic process
A9C19_RS08405	COG1028	Short-chain dehydrogenase reductase Sdr
A9C19_RS08420	COG2962	Rard protein
A9C19_RS08430	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A9C19_RS08435	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A9C19_RS08440	COG0534	Mate efflux family protein
A9C19_RS08445	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
A9C19_RS08455	COG0791	NLP P60 protein
A9C19_RS08455	COG1388	LysM domain
A9C19_RS08460	COG0714	Associated with various cellular activities
A9C19_RS08465	COG4548	von Willebrand factor, type A
A9C19_RS08470	COG0567	Dehydrogenase, E1 component
A9C19_RS08475	COG0508	dehydrogenase complex catalyzes the overall conversion of
A9C19_RS08480	COG0733	neurotransmitter:sodium symporter activity
A9C19_RS08485	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A9C19_RS08495	COG2211	Major facilitator Superfamily
A9C19_RS08510	COG1247	-acetyltransferase
A9C19_RS08515	COG2404	hydrolase activity, acting on ester bonds
A9C19_RS08535	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A9C19_RS08540	COG2112	serine threonine protein kinase
A9C19_RS08555	COG2323	membrane
A9C19_RS08580	COG1830	Aldolase
A9C19_RS08590	COG2340	Cysteine-rich secretory protein family
A9C19_RS08600	COG0596	Alpha beta hydrolase
A9C19_RS08630	COG0737	Belongs to the 5'-nucleotidase family
A9C19_RS08630	COG1525	nuclease
A9C19_RS08630	COG4085	toxin activity
A9C19_RS08635	COG3973	AAA domain
A9C19_RS08645	COG0778	Nitroreductase
A9C19_RS08650	COG0584	glycerophosphoryl diester phosphodiesterase
A9C19_RS08660	COG2855	membrane
A9C19_RS08665	COG0583	DNA-binding transcription factor activity
A9C19_RS08670	COG0583	DNA-binding transcription factor activity
A9C19_RS08675	COG0070	glutamate synthase
A9C19_RS08675	COG0069	glutamate synthase activity
A9C19_RS08675	COG0067	glutamate synthase
A9C19_RS08680	COG0493	'glutamate synthase
A9C19_RS08685	COG5002	protein histidine kinase activity
A9C19_RS08700	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
A9C19_RS08715	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A9C19_RS08720	COG2720	vancomycin resistance protein
A9C19_RS08725	COG0561	phosphatase activity
A9C19_RS08735	COG1609	Transcriptional regulator
A9C19_RS08740	COG1011	Hydrolase
A9C19_RS08755	COG1937	Protein conserved in bacteria
A9C19_RS08765	COG0640	Transcriptional regulator
A9C19_RS08785	COG2176	DNA-directed DNA polymerase activity
A9C19_RS08795	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A9C19_RS08800	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
A9C19_RS08820	COG0346	lactoylglutathione lyase activity
A9C19_RS08825	COG0400	carboxylic ester hydrolase activity
A9C19_RS08830	COG2135	peptidase activity
A9C19_RS08840	COG0656	L-ascorbic acid biosynthetic process
A9C19_RS08845	COG2027	D-alanyl-D-alanine carboxypeptidase
A9C19_RS08850	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
A9C19_RS08865	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A9C19_RS08870	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
A9C19_RS08875	COG2223	nitrite transmembrane transporter activity
A9C19_RS08900	COG0745	RESPONSE REGULATOR receiver
A9C19_RS08915	COG0501	Belongs to the peptidase M48B family
A9C19_RS08920	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A9C19_RS08950	COG3906	Belongs to the UPF0473 family
A9C19_RS08965	COG5553	Cysteine dioxygenase type I
A9C19_RS08970	COG0708	Exodeoxyribonuclease III
A9C19_RS08995	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A9C19_RS09000	COG5506	Protein of unknown function (DUF1694)
A9C19_RS09010	COG0511	ligase activity, forming carbon-carbon bonds
A9C19_RS09015	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A9C19_RS09020	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A9C19_RS09025	COG1960	acyl-CoA dehydrogenase activity
A9C19_RS09030	COG0439	Biotin carboxylase
A9C19_RS09035	COG1024	Enoyl-CoA hydratase
A9C19_RS09050	COG1164	Oligoendopeptidase f
A9C19_RS09055	COG1737	Transcriptional regulator
A9C19_RS09060	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
A9C19_RS09065	COG2610	gluconate transmembrane transporter activity
A9C19_RS09070	COG1070	Carbohydrate kinase
A9C19_RS09140	COG2205	protein histidine kinase activity
A9C19_RS09145	COG2066	Belongs to the glutaminase family
A9C19_RS09165	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
A9C19_RS09180	COG0697	spore germination
A9C19_RS09185	COG1396	sequence-specific DNA binding
A9C19_RS09195	COG0346	lactoylglutathione lyase activity
A9C19_RS09205	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
A9C19_RS09210	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A9C19_RS09220	COG0110	maltose O-acetyltransferase activity
A9C19_RS09225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A9C19_RS09230	COG2233	PERMEase
A9C19_RS09285	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A9C19_RS09295	COG4264	IucA IucC family
A9C19_RS09300	COG0019	diaminopimelate decarboxylase activity
A9C19_RS09315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A9C19_RS09320	COG2208	phosphoserine phosphatase activity
A9C19_RS09325	COG0596	Alpha beta hydrolase
A9C19_RS09335	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
A9C19_RS09370	COG0412	Dienelactone hydrolase
A9C19_RS09390	COG2972	Histidine kinase
A9C19_RS09395	COG2207	Transcriptional regulator
A9C19_RS09395	COG4753	response regulator
A9C19_RS09405	COG0747	negative chemotaxis
A9C19_RS09410	COG0601	transmembrane transport
A9C19_RS09415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A9C19_RS09425	COG0444	Belongs to the ABC transporter superfamily
A9C19_RS09430	COG4608	Belongs to the ABC transporter superfamily
A9C19_RS09450	COG0179	Fumarylacetoacetate (FAA) hydrolase
A9C19_RS09465	COG0305	Participates in initiation and elongation during chromosome replication
A9C19_RS09475	COG0604	alcohol dehydrogenase
A9C19_RS09535	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
A9C19_RS09560	COG2226	methyltransferase
A9C19_RS09570	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A9C19_RS09575	COG0477	Major facilitator Superfamily
A9C19_RS09610	COG1028	Short-chain dehydrogenase reductase Sdr
A9C19_RS09650	COG5444	nuclease activity
A9C19_RS09690	COG1028	Short-chain dehydrogenase reductase Sdr
A9C19_RS09730	COG1595	DNA-templated transcription, initiation
A9C19_RS09780	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A9C19_RS09795	COG2188	Transcriptional regulator
A9C19_RS09800	COG1131	(ABC) transporter
A9C19_RS09835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A9C19_RS09840	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A9C19_RS09840	COG2111	Na H antiporter
A9C19_RS09845	COG0651	ATP synthesis coupled electron transport
A9C19_RS09850	COG1006	Multisubunit Na H antiporter MnhC subunit
A9C19_RS09855	COG2111	Na H antiporter
A9C19_RS09865	COG1320	monovalent cation:proton antiporter activity
A9C19_RS09870	COG2212	antiporter activity
A9C19_RS09960	COG0494	nUDIX hydrolase
A9C19_RS09995	COG1476	TRANSCRIPTIONal
A9C19_RS10005	COG4974	Belongs to the 'phage' integrase family
A9C19_RS10010	COG0210	DNA helicase
A9C19_RS10015	COG1278	Cold shock
A9C19_RS10020	COG0662	Cupin 2, conserved barrel domain protein
A9C19_RS10040	COG0730	response to heat
A9C19_RS10045	COG2226	methyltransferase
A9C19_RS10050	COG0492	ferredoxin-NADP+ reductase activity
A9C19_RS10075	COG2814	Major facilitator Superfamily
A9C19_RS10080	COG3773	Cell wall hydrolase
A9C19_RS10080	COG3409	Peptidoglycan-binding domain 1 protein
A9C19_RS10085	COG1473	amidohydrolase
A9C19_RS10100	COG2217	Heavy metal translocating P-type atpase
A9C19_RS10135	COG1028	Short-chain dehydrogenase reductase Sdr
A9C19_RS10140	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A9C19_RS10145	COG1115	amino acid carrier protein
A9C19_RS10150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A9C19_RS10165	COG0514	ATP-dependent DNA helicase (RecQ)
A9C19_RS10185	COG0589	response to stress
A9C19_RS10200	COG1683	Conserved Protein
A9C19_RS10205	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
A9C19_RS10210	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
A9C19_RS10215	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A9C19_RS10220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A9C19_RS10225	COG1120	ATPase activity
A9C19_RS10230	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
A9C19_RS10235	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A9C19_RS10245	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
A9C19_RS10315	COG1492	cobalamin metabolic process
A9C19_RS10335	COG0778	Nitroreductase
A9C19_RS10340	COG0310	cobalt ion transport
A9C19_RS10355	COG1122	ATPase activity
A9C19_RS10380	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A9C19_RS10390	COG4974	Belongs to the 'phage' integrase family
A9C19_RS10400	COG2113	Glycine betaine
A9C19_RS10405	COG4176	ABC-type proline glycine betaine transport system permease component
A9C19_RS10410	COG4175	Glycine betaine
A9C19_RS10410	COG0517	IMP dehydrogenase activity
A9C19_RS10415	COG1510	regulation of RNA biosynthetic process
A9C19_RS10425	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A9C19_RS10430	COG0187	DNA topoisomerase II activity
A9C19_RS10435	COG1832	CoA-binding protein
A9C19_RS10440	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
A9C19_RS10445	COG4841	protein insertion into membrane
A9C19_RS10455	COG0824	Thioesterase
A9C19_RS10475	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A9C19_RS10485	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
A9C19_RS10505	COG0071	Belongs to the small heat shock protein (HSP20) family
A9C19_RS10515	COG4191	Histidine kinase
A9C19_RS10525	COG0300	oxidoreductase activity
A9C19_RS10535	COG1335	isochorismatase
A9C19_RS10540	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
A9C19_RS10545	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
A9C19_RS10555	COG1607	acyl-coa hydrolase
A9C19_RS10570	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
A9C19_RS10600	COG4989	oxidoreductase activity
A9C19_RS10610	COG0673	inositol 2-dehydrogenase activity
A9C19_RS10615	COG1082	Xylose isomerase domain protein TIM barrel
A9C19_RS10625	COG5577	PFAM Coat F domain
A9C19_RS10640	COG4846	Membrane protein involved in cytochrome C biogenesis
A9C19_RS10645	COG2201	protein-glutamate methylesterase activity
A9C19_RS10650	COG0785	Cytochrome C biogenesis protein
A9C19_RS10660	COG3763	UPF0154 protein
A9C19_RS10685	COG4224	UPF0291 protein
A9C19_RS10690	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
A9C19_RS10695	COG1388	LysM domain
A9C19_RS10700	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
A9C19_RS10710	COG0673	inositol 2-dehydrogenase activity
A9C19_RS10715	COG0673	inositol 2-dehydrogenase activity
A9C19_RS10730	COG4753	response regulator
A9C19_RS10730	COG2207	Transcriptional regulator
A9C19_RS10735	COG2972	Histidine kinase
A9C19_RS10745	COG0395	ABC-type sugar transport system, permease component
A9C19_RS10755	COG0174	glutamine synthetase
A9C19_RS10760	COG0789	Transcriptional regulator
A9C19_RS10765	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
A9C19_RS10770	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A9C19_RS10775	COG2860	membrane
A9C19_RS10795	COG0464	growth
A9C19_RS10805	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
A9C19_RS10810	COG5609	conserved protein (DUF2294)
A9C19_RS10815	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
A9C19_RS10820	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
A9C19_RS10825	COG0789	Transcriptional regulator
A9C19_RS10830	COG1132	(ABC) transporter
A9C19_RS10850	COG4550	Control of competence regulator ComK, YlbF/YmcA
A9C19_RS10855	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A9C19_RS10860	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A9C19_RS10885	COG1335	isochorismatase
A9C19_RS10890	COG3344	reverse transcriptase
A9C19_RS10895	COG1063	alcohol dehydrogenase
A9C19_RS10900	COG0156	8-amino-7-oxononanoate synthase activity
A9C19_RS10905	COG1063	alcohol dehydrogenase
A9C19_RS10910	COG1013	pyruvate-flavodoxin oxidoreductase activity
A9C19_RS10915	COG0674	pyruvate-flavodoxin oxidoreductase activity
A9C19_RS10915	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A9C19_RS10925	COG2359	stage V sporulation protein S
A9C19_RS10930	COG1692	metallophosphoesterase
A9C19_RS10935	COG1418	mRNA catabolic process
A9C19_RS10940	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
A9C19_RS10945	COG1546	Belongs to the CinA family
A9C19_RS10945	COG1058	Belongs to the CinA family
A9C19_RS10950	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A9C19_RS10955	COG1426	Protein conserved in bacteria
A9C19_RS10970	COG0300	oxidoreductase activity
A9C19_RS10975	COG0612	Peptidase, M16
A9C19_RS10980	COG0612	Peptidase, M16
A9C19_RS10985	COG2814	Major facilitator Superfamily
A9C19_RS10990	COG1079	Belongs to the binding-protein-dependent transport system permease family
A9C19_RS10995	COG4603	Belongs to the binding-protein-dependent transport system permease family
A9C19_RS11000	COG3845	ABC transporter
A9C19_RS11005	COG1744	ABC transporter substrate-binding protein PnrA-like
A9C19_RS11010	COG2188	Transcriptional regulator
A9C19_RS11015	COG4980	gas vesicle protein
A9C19_RS11015	COG1674	ftsk spoiiie
A9C19_RS11025	COG0740	serine-type endopeptidase activity
A9C19_RS11030	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A9C19_RS11040	COG0527	aspartate kinase activity
A9C19_RS11045	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A9C19_RS11050	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A9C19_RS11055	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A9C19_RS11060	COG1873	PFAM PRC-barrel domain
A9C19_RS11065	COG0612	Peptidase, M16
A9C19_RS11070	COG0726	polysaccharide deacetylase
A9C19_RS11075	COG1185	polyribonucleotide nucleotidyltransferase activity
A9C19_RS11085	COG0196	riboflavin kinase activity
A9C19_RS11090	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
A9C19_RS11095	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
A9C19_RS11100	COG1550	Protein conserved in bacteria
A9C19_RS11105	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
A9C19_RS11110	COG1358	cellular component organization or biogenesis
A9C19_RS11115	COG2740	Nucleic-acid-binding protein implicated in transcription termination
A9C19_RS11120	COG0195	Participates in both transcription termination and antitermination
A9C19_RS11130	COG0779	Required for maturation of 30S ribosomal subunits
A9C19_RS11135	COG2176	DNA-directed DNA polymerase activity
A9C19_RS11140	COG0442	prolyl-tRNA aminoacylation
A9C19_RS11145	COG0750	zinc metalloprotease
A9C19_RS11150	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
A9C19_RS11155	COG4589	Belongs to the CDS family
A9C19_RS11160	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A9C19_RS11165	COG0233	cytoplasmic translational termination
A9C19_RS11170	COG0528	UMP kinase activity
A9C19_RS11175	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
A9C19_RS11195	COG1191	sigma factor activity
A9C19_RS11200	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
A9C19_RS11205	COG1776	CheC inhibitor of MCP methylation
A9C19_RS11210	COG0835	chemotaxis
A9C19_RS11215	COG0643	Histidine kinase
A9C19_RS11215	COG2198	Histidine kinase
A9C19_RS11220	COG2201	protein-glutamate methylesterase activity
A9C19_RS11225	COG0455	bacterial-type flagellum organization
A9C19_RS11230	COG1419	protein localization to endoplasmic reticulum
A9C19_RS11235	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A9C19_RS11240	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A9C19_RS11245	COG1684	flagellar biosynthetic protein fliR
A9C19_RS11250	COG1987	bacterial-type flagellum assembly
A9C19_RS11255	COG1338	Plays a role in the flagellum-specific transport system
A9C19_RS11260	COG3190	flagellar
A9C19_RS11265	COG2201	protein-glutamate methylesterase activity
A9C19_RS11270	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A9C19_RS11270	COG1776	CheC inhibitor of MCP methylation
A9C19_RS11275	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A9C19_RS11280	COG1580	Controls the rotational direction of flagella during chemotaxis
A9C19_RS11285	COG1582	Flagellar protein (FlbD)
A9C19_RS11290	COG4786	Flagellar basal body rod
A9C19_RS11300	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
A9C19_RS11305	COG3144	bacterial-type flagellum assembly
A9C19_RS11315	COG2882	bacterial-type flagellum organization
A9C19_RS11320	COG1157	protein secretion by the type III secretion system
A9C19_RS11325	COG1317	bacterial-type flagellum organization
A9C19_RS11330	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A9C19_RS11335	COG1766	The M ring may be actively involved in energy transduction
A9C19_RS11340	COG1677	Flagellar hook-basal body complex protein FliE
A9C19_RS11345	COG1558	bacterial-type flagellum-dependent cell motility
A9C19_RS11350	COG1815	bacterial-type flagellum-dependent cell motility
A9C19_RS11355	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
A9C19_RS11360	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
A9C19_RS11370	COG4974	Belongs to the 'phage' integrase family
A9C19_RS11375	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
A9C19_RS11380	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A9C19_RS11385	COG0758	DNA mediated transformation
A9C19_RS11390	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
A9C19_RS11400	COG2257	FlhB HrpN YscU SpaS Family
A9C19_RS11425	COG0335	large ribosomal subunit rRNA binding
A9C19_RS11430	COG0336	Belongs to the RNA methyltransferase TrmD family
A9C19_RS11435	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
A9C19_RS11445	COG1837	Belongs to the UPF0109 family
A9C19_RS11450	COG0228	four-way junction DNA binding
A9C19_RS11455	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A9C19_RS11465	COG0552	protein localization to endoplasmic reticulum
A9C19_RS11470	COG1196	nuclear chromosome segregation
A9C19_RS11475	COG0571	ribonuclease III activity
A9C19_RS11480	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A9C19_RS11485	COG1028	Short-chain dehydrogenase reductase Sdr
A9C19_RS11490	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A9C19_RS11495	COG0416	fatty acid biosynthetic process
A9C19_RS11500	COG1349	DNA-binding transcription factor activity
A9C19_RS11505	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A9C19_RS11510	COG1760	l-serine dehydratase
A9C19_RS11515	COG1760	l-serine dehydratase
A9C19_RS11520	COG1461	Dihydroxyacetone kinase
A9C19_RS11525	COG1302	Protein conserved in bacteria
A9C19_RS11530	COG0227	Belongs to the bacterial ribosomal protein bL28 family
A9C19_RS11540	COG1564	THIamine pyrophosphokinase
A9C19_RS11545	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A9C19_RS11550	COG1162	GTPase activity
A9C19_RS11555	COG2815	serine threonine protein kinase
A9C19_RS11555	COG0515	serine threonine protein kinase
A9C19_RS11560	COG0631	protein serine/threonine phosphatase activity
A9C19_RS11565	COG0820	rRNA (adenine-C2-)-methyltransferase activity
A9C19_RS11570	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A9C19_RS11570	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A9C19_RS11575	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
A9C19_RS11585	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A9C19_RS11590	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A9C19_RS11595	COG1758	RNA polymerase activity
A9C19_RS11600	COG0194	GDP metabolic process
A9C19_RS11605	COG2052	Domain of unknown function (DUF370)
A9C19_RS11610	COG1561	YicC-like family, N-terminal region
A9C19_RS11615	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A9C19_RS11635	COG1648	precorrin-2 dehydrogenase activity
A9C19_RS11640	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
A9C19_RS11650	COG0529	Catalyzes the synthesis of activated sulfate
A9C19_RS11655	COG2046	Belongs to the sulfate adenylyltransferase family
A9C19_RS11660	COG0306	phosphate transporter
A9C19_RS11680	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
A9C19_RS11685	COG0284	orotidine-5'-phosphate decarboxylase activity
A9C19_RS11700	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
A9C19_RS11705	COG0505	Belongs to the CarA family
A9C19_RS11710	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A9C19_RS11715	COG0540	Belongs to the ATCase OTCase family
A9C19_RS11725	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
A9C19_RS11730	COG0564	pseudouridine synthase activity
A9C19_RS11735	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
A9C19_RS11740	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A9C19_RS11750	COG3599	regulation of cell shape
A9C19_RS11755	COG2302	S4 RNA-binding domain
A9C19_RS11760	COG0762	integral membrane protein
A9C19_RS11765	COG1799	cell septum assembly
A9C19_RS11770	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
A9C19_RS11775	COG1496	oxidoreductase activity
A9C19_RS11780	COG1873	PFAM PRC-barrel domain
A9C19_RS11785	COG1191	sigma factor activity
A9C19_RS11790	COG1191	sigma factor activity
A9C19_RS11800	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A9C19_RS11805	COG0849	cell division
A9C19_RS11810	COG3856	small basic protein
A9C19_RS11815	COG3879	Bacterial protein of unknown function (DUF881)
A9C19_RS11820	COG3879	Bacterial protein of unknown function (DUF881)
A9C19_RS11825	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
A9C19_RS11835	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
A9C19_RS11840	COG0772	Belongs to the SEDS family
A9C19_RS11845	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
A9C19_RS11850	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A9C19_RS11860	COG0768	penicillin binding
A9C19_RS11865	COG0768	penicillin binding
A9C19_RS11870	COG4839	cell division protein FtsL
A9C19_RS11875	COG0275	rRNA processing
A9C19_RS11880	COG2001	Belongs to the MraZ family
A9C19_RS11885	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
A9C19_RS11895	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A9C19_RS11900	COG0454	-acetyltransferase
A9C19_RS11910	COG1024	Enoyl-CoA hydratase
A9C19_RS11915	COG0333	Belongs to the bacterial ribosomal protein bL32 family
A9C19_RS11920	COG1399	metal-binding, possibly nucleic acid-binding protein
A9C19_RS11925	COG1323	Belongs to the UPF0348 family
A9C19_RS11930	COG3480	Lon protease (S16) C-terminal proteolytic domain
A9C19_RS11935	COG1752	Esterase of the alpha-beta hydrolase superfamily
A9C19_RS11940	COG3314	Sporulation integral membrane protein YlbJ
A9C19_RS11945	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
A9C19_RS11950	COG0742	ribosomal rna small subunit methyltransferase
A9C19_RS11965	COG3679	Belongs to the UPF0342 family
A9C19_RS11990	COG2340	Cysteine-rich secretory protein family
A9C19_RS11995	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
A9C19_RS12015	COG0628	permease
A9C19_RS12030	COG3336	cytochrome c oxidase
A9C19_RS12040	COG1845	cytochrome c oxidase, subunit III
A9C19_RS12045	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A9C19_RS12055	COG0109	protoheme IX farnesyltransferase activity
A9C19_RS12060	COG1612	heme a metabolic process
A9C19_RS12065	COG0415	Belongs to the DNA photolyase family
A9C19_RS12070	COG2226	methyltransferase
A9C19_RS12080	COG0772	Belongs to the SEDS family
A9C19_RS12085	COG4838	Belongs to the UPF0358 family
A9C19_RS12090	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
A9C19_RS12095	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
A9C19_RS12110	COG4896	Protein conserved in bacteria
A9C19_RS12125	COG1217	gtp-binding protein TYPA
A9C19_RS12140	COG0483	inositol monophosphate 1-phosphatase activity
A9C19_RS12150	COG4493	Belongs to the UPF0637 family
A9C19_RS12155	COG4476	Belongs to the UPF0223 family
A9C19_RS12165	COG1982	Orn Lys Arg decarboxylase major
A9C19_RS12185	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A9C19_RS12195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A9C19_RS12215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A9C19_RS12220	COG0508	dehydrogenase complex catalyzes the overall conversion of
A9C19_RS12225	COG0022	dehydrogenase e1 component
A9C19_RS12230	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A9C19_RS12235	COG0497	DNA recombination
A9C19_RS12245	COG0242	peptide deformylase activity
A9C19_RS12250	COG0561	phosphatase activity
A9C19_RS12255	COG0697	spore germination
A9C19_RS12265	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A9C19_RS12270	COG0569	domain protein
A9C19_RS12275	COG3180	Ammonia monooxygenase
A9C19_RS12280	COG0514	ATP-dependent DNA helicase (RecQ)
A9C19_RS12290	COG1077	Cell shape determining protein MreB Mrl
A9C19_RS12300	COG1960	acyl-CoA dehydrogenase activity
A9C19_RS12305	COG2309	aminopeptidase activity
A9C19_RS12310	COG0523	cobalamin synthesis protein
A9C19_RS12315	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A9C19_RS12320	COG3275	phosphorelay sensor kinase activity
A9C19_RS12330	COG0488	(ABC) transporter
A9C19_RS12340	COG1966	Carbon starvation protein
A9C19_RS12375	COG1764	response to oxidative stress
A9C19_RS12380	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A9C19_RS12380	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A9C19_RS12380	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A9C19_RS12385	COG1105	Belongs to the carbohydrate kinase PfkB family
A9C19_RS12390	COG1349	DNA-binding transcription factor activity
A9C19_RS12395	COG0577	efflux transmembrane transporter activity
A9C19_RS12400	COG1136	(ABC) transporter
A9C19_RS12405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A9C19_RS12420	COG1132	(ABC) transporter
A9C19_RS12425	COG1132	(ABC) transporter
A9C19_RS12430	COG0456	acetyltransferase
A9C19_RS12430	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
A9C19_RS12435	COG1970	mechanosensitive ion channel activity
A9C19_RS12440	COG0840	transmembrane signaling receptor activity
A9C19_RS12445	COG2176	DNA-directed DNA polymerase activity
A9C19_RS12455	COG0004	ammonium transporteR
A9C19_RS12460	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A9C19_RS12475	COG0392	lysyltransferase activity
A9C19_RS12475	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
A9C19_RS12490	COG4149	molybdate abc transporter
A9C19_RS12495	COG0725	ABC transporter, periplasmic molybdate-binding protein
A9C19_RS12505	COG0314	molybdopterin synthase activity
A9C19_RS12510	COG1763	Mo-molybdopterin cofactor biosynthetic process
A9C19_RS12515	COG0303	'Molybdopterin
A9C19_RS12520	COG0746	molybdenum cofactor guanylyltransferase activity
A9C19_RS12525	COG0450	alkyl hydroperoxide reductase
A9C19_RS12530	COG0668	transmembrane transport
A9C19_RS12540	COG1473	amidohydrolase
A9C19_RS12545	COG2171	N-acyltransferase activity
A9C19_RS12550	COG0583	DNA-binding transcription factor activity
A9C19_RS12560	COG0517	IMP dehydrogenase activity
A9C19_RS12565	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
A9C19_RS12570	COG4703	Protein of unknown function (DUF1797)
A9C19_RS12590	COG2200	EAL domain
A9C19_RS12595	COG1028	Short-chain dehydrogenase reductase Sdr
A9C19_RS12600	COG1408	metallophosphoesterase
A9C19_RS12605	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A9C19_RS12610	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A9C19_RS12625	COG1376	ErfK ybiS ycfS ynhG family protein
A9C19_RS12630	COG2814	Major facilitator Superfamily
A9C19_RS12635	COG2770	Histidine kinase
A9C19_RS12635	COG3437	response regulator, receiver
A9C19_RS12645	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A9C19_RS12650	COG0784	Response regulator, receiver
A9C19_RS12650	COG0835	chemotaxis
A9C19_RS12675	COG3706	GGDEF domain
A9C19_RS12690	COG0598	Magnesium transport protein CorA
A9C19_RS12695	COG0436	Aminotransferase
A9C19_RS12700	COG4191	Histidine kinase
A9C19_RS12710	COG1960	acyl-CoA dehydrogenase activity
A9C19_RS12725	COG1250	3-hydroxyacyl-CoA dehydrogenase
A9C19_RS12730	COG1309	transcriptional regulator
A9C19_RS12735	COG0318	PFAM AMP-dependent synthetase and ligase
A9C19_RS12740	COG1028	Short-chain dehydrogenase reductase Sdr
A9C19_RS12750	COG0768	penicillin binding
A9C19_RS12755	COG0456	acetyltransferase
A9C19_RS12760	COG2084	Dehydrogenase
A9C19_RS12775	COG1028	Short-chain dehydrogenase reductase Sdr
A9C19_RS12780	COG1533	DNA photolyase activity
A9C19_RS12790	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A9C19_RS12795	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A9C19_RS12800	COG2190	(PTS) system
A9C19_RS12800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A9C19_RS12800	COG1263	PTS System
A9C19_RS12805	COG3711	transcriptional antiterminator
A9C19_RS12830	COG0205	6-phosphofructokinase activity
A9C19_RS12840	COG4943	cyclic-guanylate-specific phosphodiesterase activity
A9C19_RS12845	COG0006	proline dipeptidase activity
A9C19_RS12850	COG1215	transferase activity, transferring glycosyl groups
A9C19_RS12865	COG2217	Heavy metal translocating P-type atpase
A9C19_RS12870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A9C19_RS12875	COG2244	polysaccharide biosynthetic process
A9C19_RS12895	COG3773	Cell wall hydrolase
A9C19_RS12905	COG0702	epimerase
A9C19_RS12910	COG4873	Protein conserved in bacteria
A9C19_RS12920	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
A9C19_RS12925	COG0602	queuosine metabolic process
A9C19_RS12930	COG0720	synthase
A9C19_RS12935	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
A9C19_RS12950	COG1253	flavin adenine dinucleotide binding
A9C19_RS12960	COG3949	Membrane
A9C19_RS12965	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A9C19_RS12975	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
A9C19_RS12980	COG1360	Flagellar Motor Protein
A9C19_RS12985	COG1846	Transcriptional regulator
A9C19_RS13000	COG2861	carbohydrate metabolic process
A9C19_RS13010	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
A9C19_RS13015	COG0235	Class ii aldolase
A9C19_RS13020	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
A9C19_RS13025	COG1850	ribulose-bisphosphate carboxylase activity
A9C19_RS13030	COG0436	Aminotransferase
A9C19_RS13035	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A9C19_RS13040	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
A9C19_RS13045	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
A9C19_RS13050	COG5002	protein histidine kinase activity
A9C19_RS13055	COG3594	Acyltransferase
A9C19_RS13065	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A9C19_RS13070	COG0501	Belongs to the peptidase M48B family
A9C19_RS13090	COG1191	sigma factor activity
A9C19_RS13095	COG0861	Integral membrane protein TerC family
A9C19_RS13100	COG0586	Pfam SNARE associated Golgi protein
A9C19_RS13110	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
A9C19_RS13115	COG1523	belongs to the glycosyl hydrolase 13 family
A9C19_RS13120	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
A9C19_RS13125	COG3285	dna ligase
A9C19_RS13125	COG1793	dna ligase
A9C19_RS13135	COG1846	Transcriptional regulator
A9C19_RS13155	COG0789	Transcriptional regulator
A9C19_RS13165	COG2258	MOSC domain
A9C19_RS13170	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
A9C19_RS13185	COG3764	Sortase (surface protein transpeptidase)
A9C19_RS13190	COG0028	Belongs to the TPP enzyme family
A9C19_RS13230	COG0697	spore germination
A9C19_RS13250	COG1363	Peptidase, m42
A9C19_RS13255	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
A9C19_RS13290	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
A9C19_RS13295	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
A9C19_RS13305	COG1090	epimerase
A9C19_RS13315	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A9C19_RS13320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A9C19_RS13325	COG1116	anion transmembrane transporter activity
A9C19_RS13330	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
A9C19_RS13335	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A9C19_RS13340	COG0385	Bile acid
A9C19_RS13350	COG2720	vancomycin resistance protein
A9C19_RS13360	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A9C19_RS13390	COG1595	DNA-templated transcription, initiation
A9C19_RS13395	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
A9C19_RS13415	COG1366	Belongs to the anti-sigma-factor antagonist family
A9C19_RS13420	COG0604	alcohol dehydrogenase
A9C19_RS13425	COG3706	GGDEF domain
A9C19_RS13430	COG0456	acetyltransferase
A9C19_RS13435	COG0456	acetyltransferase
A9C19_RS13455	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A9C19_RS13460	COG3279	Response regulator of the LytR AlgR family
A9C19_RS13465	COG0745	RESPONSE REGULATOR receiver
A9C19_RS13465	COG2972	Histidine kinase
A9C19_RS13470	COG3300	MHYT domain
A9C19_RS13470	COG5001	Diguanylate cyclase
A9C19_RS13490	COG0579	oxidoreductase
A9C19_RS13500	COG2385	sporulation resulting in formation of a cellular spore
A9C19_RS13505	COG0454	-acetyltransferase
A9C19_RS13540	COG0772	Belongs to the SEDS family
A9C19_RS13575	COG0768	penicillin binding
A9C19_RS13585	COG3541	Predicted nucleotidyltransferase
A9C19_RS13600	COG2252	PERMEase
A9C19_RS13615	COG0840	transmembrane signaling receptor activity
A9C19_RS13620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A9C19_RS13655	COG4129	membrane
A9C19_RS13660	COG0861	Integral membrane protein TerC family
A9C19_RS13720	COG5444	nuclease activity
A9C19_RS13740	COG2076	Multidrug Resistance protein
A9C19_RS13765	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A9C19_RS13765	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A9C19_RS13775	COG3314	Sporulation integral membrane protein YlbJ
A9C19_RS13785	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A9C19_RS13800	COG1132	(ABC) transporter
A9C19_RS13805	COG2706	6-phosphogluconolactonase activity
A9C19_RS13815	COG3655	Transcriptional regulator
A9C19_RS13985	COG2323	membrane
A9C19_RS13995	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
A9C19_RS14010	COG2385	sporulation resulting in formation of a cellular spore
A9C19_RS14010	COG2247	cell wall binding repeat
A9C19_RS14015	COG2329	Antibiotic biosynthesis monooxygenase
A9C19_RS14035	COG0561	phosphatase activity
A9C19_RS14045	COG2508	Transcriptional regulator
A9C19_RS14050	COG2268	Band 7 protein
A9C19_RS14070	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A9C19_RS14075	COG1012	belongs to the aldehyde dehydrogenase family
A9C19_RS14080	COG0506	proline dehydrogenase activity
A9C19_RS14095	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
A9C19_RS14100	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
A9C19_RS14110	COG5002	protein histidine kinase activity
A9C19_RS14120	COG3480	Lon protease (S16) C-terminal proteolytic domain
A9C19_RS14140	COG0754	glutathionylspermidine amidase activity
A9C19_RS14155	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
A9C19_RS14160	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
A9C19_RS14165	COG0534	Mate efflux family protein
A9C19_RS14170	COG1309	transcriptional regulator
A9C19_RS14175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A9C19_RS14180	COG0366	Alpha amylase catalytic
A9C19_RS14215	COG5578	integral membrane protein
A9C19_RS14245	COG1309	transcriptional regulator
A9C19_RS14250	COG1131	(ABC) transporter
A9C19_RS14295	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A9C19_RS14305	COG0398	Pfam SNARE associated Golgi protein
A9C19_RS14325	COG4134	Bacterial extracellular solute-binding protein
A9C19_RS14330	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A9C19_RS14330	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A9C19_RS14335	COG5002	protein histidine kinase activity
A9C19_RS14340	COG0745	RESPONSE REGULATOR receiver
A9C19_RS14350	COG2199	diguanylate cyclase activity
A9C19_RS14350	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
A9C19_RS14360	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
A9C19_RS14365	COG0254	rRNA binding
A9C19_RS14370	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A9C19_RS14400	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
A9C19_RS14405	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A9C19_RS14415	COG1609	Transcriptional regulator
A9C19_RS14430	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A9C19_RS14440	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
A9C19_RS14445	COG1028	Short-chain dehydrogenase reductase Sdr
A9C19_RS14460	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
A9C19_RS14470	COG1606	tRNA processing
A9C19_RS14475	COG3875	lactate racemase activity
A9C19_RS14485	COG1929	Belongs to the glycerate kinase type-1 family
A9C19_RS14490	COG3835	regulator
A9C19_RS14500	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
A9C19_RS14505	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
A9C19_RS14510	COG1691	(AIR) carboxylase
A9C19_RS14515	COG1070	Carbohydrate kinase
A9C19_RS14520	COG1606	tRNA processing
A9C19_RS14525	COG1028	Short-chain dehydrogenase reductase Sdr
A9C19_RS14535	COG1904	glucuronate isomerase
A9C19_RS14540	COG1940	carbohydrate kinase activity
A9C19_RS14545	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
A9C19_RS14570	COG1609	Transcriptional regulator
A9C19_RS14580	COG1028	Short-chain dehydrogenase reductase Sdr
A9C19_RS14585	COG0840	transmembrane signaling receptor activity
A9C19_RS14625	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A9C19_RS14630	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A9C19_RS14635	COG0640	Transcriptional regulator
A9C19_RS14645	COG1124	(ABC) transporter
A9C19_RS14650	COG0444	Belongs to the ABC transporter superfamily
A9C19_RS14655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A9C19_RS14660	COG0601	transmembrane transport
A9C19_RS14665	COG0747	negative chemotaxis
A9C19_RS14680	COG1028	Short-chain dehydrogenase reductase Sdr
A9C19_RS14690	COG0701	Predicted permease
A9C19_RS14695	COG0523	cobalamin synthesis protein
A9C19_RS14705	COG0402	S-adenosylhomocysteine deaminase activity
A9C19_RS14710	COG2211	Major facilitator Superfamily
A9C19_RS14725	COG0492	ferredoxin-NADP+ reductase activity
A9C19_RS14735	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A9C19_RS14845	COG4974	Belongs to the 'phage' integrase family
A9C19_RS14880	COG0626	cystathionine gamma-synthase activity
A9C19_RS14885	COG0626	cystathionine gamma-synthase activity
A9C19_RS14890	COG1999	signal sequence binding
A9C19_RS14900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A9C19_RS14915	COG2382	esterase
A9C19_RS14925	COG2153	protein acetylation
A9C19_RS14930	COG2323	membrane
A9C19_RS14940	COG0210	DNA helicase
A9C19_RS14960	COG2323	membrane
A9C19_RS15005	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
A9C19_RS15015	COG0351	phosphomethylpyrimidine kinase
A9C19_RS15020	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A9C19_RS15025	COG2022	thiamine diphosphate biosynthetic process
A9C19_RS15030	COG2104	thiamine diphosphate biosynthetic process
A9C19_RS15035	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A9C19_RS15040	COG0352	thiamine-phosphate diphosphorylase activity
A9C19_RS15045	COG0569	domain protein
A9C19_RS15045	COG0475	glutathione-regulated potassium exporter activity
A9C19_RS15050	COG2239	Acts as a magnesium transporter
A9C19_RS15055	COG0772	Belongs to the SEDS family
A9C19_RS15060	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
A9C19_RS15065	COG0564	pseudouridine synthase activity
A9C19_RS15070	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A9C19_RS15075	COG2357	RelA SpoT domain protein
A9C19_RS15085	COG4116	CYTH
A9C19_RS15090	COG0741	lytic transglycosylase activity
A9C19_RS15095	COG2346	COG2346, Truncated hemoglobins
A9C19_RS15100	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
A9C19_RS15105	COG1164	Oligoendopeptidase f
A9C19_RS15115	COG4469	Competence protein
A9C19_RS15120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A9C19_RS15125	COG4862	establishment of competence for transformation
A9C19_RS15130	COG0861	Integral membrane protein TerC family
A9C19_RS15140	COG1393	Belongs to the ArsC family
A9C19_RS15145	COG0456	acetyltransferase
A9C19_RS15150	COG4608	Belongs to the ABC transporter superfamily
A9C19_RS15155	COG0444	Belongs to the ABC transporter superfamily
A9C19_RS15160	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A9C19_RS15165	COG0601	transmembrane transport
A9C19_RS15170	COG4166	transmembrane transport
A9C19_RS15180	COG0180	Tryptophanyl-tRNA synthetase
A9C19_RS15190	COG5504	Zn-dependent protease
A9C19_RS15195	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A9C19_RS15200	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A9C19_RS15215	COG1744	ABC transporter substrate-binding protein PnrA-like
A9C19_RS15225	COG2267	carboxylic ester hydrolase activity
A9C19_RS15245	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
A9C19_RS15250	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
A9C19_RS15255	COG0505	Belongs to the CarA family
A9C19_RS15265	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
A9C19_RS15270	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
A9C19_RS15275	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
A9C19_RS15285	COG2151	metal-sulfur cluster biosynthetic enzyme
A9C19_RS15290	COG1073	alpha beta
A9C19_RS15295	COG0561	phosphatase activity
A9C19_RS15310	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A9C19_RS15315	COG1307	EDD domain protein, DegV family
A9C19_RS15325	COG0840	transmembrane signaling receptor activity
A9C19_RS15325	COG5278	phosphoserine phosphatase activity
A9C19_RS15335	COG2996	Protein conserved in bacteria
A9C19_RS15340	COG1666	GTP binding
A9C19_RS15345	COG0646	methionine synthase
A9C19_RS15345	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
A9C19_RS15350	COG1410	methionine synthase
A9C19_RS15350	COG0646	methionine synthase
A9C19_RS15365	COG1028	Short-chain dehydrogenase reductase Sdr
A9C19_RS15370	COG0366	Alpha amylase catalytic
A9C19_RS15375	COG1917	Cupin 2, conserved barrel domain protein
A9C19_RS15375	COG2207	Transcriptional regulator
A9C19_RS15380	COG0534	Mate efflux family protein
A9C19_RS15400	COG1562	ergosterol biosynthetic process
A9C19_RS15415	COG0367	asparagine synthase
A9C19_RS15430	COG1511	domain protein
A9C19_RS15430	COG0842	Transport permease protein
A9C19_RS15435	COG1131	(ABC) transporter
A9C19_RS15445	COG0179	Fumarylacetoacetate (FAA) hydrolase
A9C19_RS15485	COG1403	HNH endonuclease
A9C19_RS15490	COG0419	ATPase involved in DNA repair
A9C19_RS15495	COG0420	3'-5' exonuclease activity
A9C19_RS15500	COG1074	ATP-dependent DNA helicase activity
A9C19_RS15505	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
A9C19_RS15515	COG0681	Belongs to the peptidase S26 family
A9C19_RS15520	COG0398	Pfam SNARE associated Golgi protein
A9C19_RS15535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A9C19_RS15540	COG0765	amino acid transport
A9C19_RS15545	COG1126	abc transporter atp-binding protein
A9C19_RS15550	COG4903	ComK protein
A9C19_RS15560	COG2224	Isocitrate lyase
A9C19_RS15565	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
A9C19_RS15570	COG0501	Belongs to the peptidase M48B family
A9C19_RS15580	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
A9C19_RS15585	COG1396	sequence-specific DNA binding
A9C19_RS15590	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A9C19_RS15595	COG0363	glucosamine-6-phosphate deaminase activity
A9C19_RS15600	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A9C19_RS15600	COG1116	anion transmembrane transporter activity
A9C19_RS15605	COG4120	Belongs to the binding-protein-dependent transport system permease family
A9C19_RS15615	COG0318	PFAM AMP-dependent synthetase and ligase
A9C19_RS15620	COG0095	Lipoate-protein ligase
A9C19_RS15625	COG1234	tRNA 3'-trailer cleavage
A9C19_RS15635	COG1609	Transcriptional regulator
A9C19_RS15645	COG1619	proteins homologs of microcin C7 resistance protein MccF
A9C19_RS15665	COG0546	phosphoglycolate phosphatase activity
A9C19_RS15685	COG0154	amidase activity
A9C19_RS15690	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
A9C19_RS15695	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
A9C19_RS15700	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A9C19_RS15705	COG2329	Antibiotic biosynthesis monooxygenase
A9C19_RS15715	COG3069	C4-dicarboxylate transmembrane transporter activity
A9C19_RS15720	COG5520	Belongs to the glycosyl hydrolase 30 family
A9C19_RS15730	COG2723	6-phospho-beta-galactosidase activity
A9C19_RS15745	COG0667	Aldo Keto reductase
A9C19_RS15750	COG4753	response regulator
A9C19_RS15750	COG2207	Transcriptional regulator
A9C19_RS15755	COG3275	phosphorelay sensor kinase activity
A9C19_RS15765	COG0395	ABC-type sugar transport system, permease component
A9C19_RS15770	COG4209	transmembrane transport
A9C19_RS15775	COG0667	Aldo Keto reductase
A9C19_RS15790	COG1131	(ABC) transporter
A9C19_RS15795	COG2188	Transcriptional regulator
A9C19_RS15815	COG1473	amidohydrolase
A9C19_RS15825	COG4473	ABC transporter
A9C19_RS15830	COG1131	(ABC) transporter
A9C19_RS15840	COG0537	adenosine 5'-monophosphoramidase activity
A9C19_RS15845	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
A9C19_RS15860	COG4980	gas vesicle protein
A9C19_RS15865	COG1846	Transcriptional regulator
A9C19_RS15910	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A9C19_RS15920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A9C19_RS15925	COG1442	glycosyl transferase family 8
A9C19_RS15930	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A9C19_RS15935	COG1442	glycosyl transferase family 8
A9C19_RS15935	COG1216	Glycosyl transferase, family 2
A9C19_RS15980	COG3481	metal-dependent phosphohydrolase, HD sub domain
A9C19_RS15985	COG4717	serine-type aminopeptidase activity
A9C19_RS15990	COG0420	3'-5' exonuclease activity
A9C19_RS16000	COG1668	transmembrane transport
A9C19_RS16005	COG4152	abc transporter atp-binding protein
A9C19_RS16015	COG1024	Enoyl-CoA hydratase
A9C19_RS16020	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A9C19_RS16035	COG4589	Belongs to the CDS family
A9C19_RS16045	COG0561	phosphatase activity
A9C19_RS16050	COG3679	Belongs to the UPF0342 family
A9C19_RS16055	COG4399	Belongs to the UPF0754 family
A9C19_RS16065	COG0189	ligase activity
A9C19_RS16070	COG0189	ligase activity
A9C19_RS16095	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A9C19_RS16105	COG2508	Transcriptional regulator
A9C19_RS16110	COG3842	ATPase activity
A9C19_RS16125	COG0702	epimerase
A9C19_RS16130	COG0393	Putative heavy-metal-binding
A9C19_RS16145	COG0589	response to stress
A9C19_RS16155	COG0439	Biotin carboxylase
A9C19_RS16160	COG3665	Urea carboxylase-associated protein
A9C19_RS16170	COG0531	amino acid
A9C19_RS16185	COG1757	Na H antiporter
A9C19_RS16190	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A9C19_RS16195	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A9C19_RS16205	COG0589	response to stress
A9C19_RS16210	COG0659	secondary active sulfate transmembrane transporter activity
A9C19_RS16215	COG1011	Hydrolase
A9C19_RS16220	COG0586	Pfam SNARE associated Golgi protein
A9C19_RS16225	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A9C19_RS16260	COG1595	DNA-templated transcription, initiation
A9C19_RS16265	COG0753	catalase activity
A9C19_RS16270	COG0673	inositol 2-dehydrogenase activity
A9C19_RS16275	COG0561	phosphatase activity
A9C19_RS16280	COG0640	Transcriptional regulator
A9C19_RS16295	COG0697	spore germination
A9C19_RS16325	COG2719	SpoVR family
A9C19_RS16345	COG5002	protein histidine kinase activity
A9C19_RS16350	COG0745	RESPONSE REGULATOR receiver
A9C19_RS16360	COG1388	LysM domain
A9C19_RS16365	COG2132	Multicopper oxidase
A9C19_RS16370	COG2608	mercury ion transmembrane transporter activity
A9C19_RS16380	COG0860	N-Acetylmuramoyl-L-alanine amidase
A9C19_RS16385	COG0860	N-Acetylmuramoyl-L-alanine amidase
A9C19_RS16395	COG2719	SpoVR family
A9C19_RS16405	COG1959	2 iron, 2 sulfur cluster binding
A9C19_RS16425	COG0431	NADPH-dependent FMN reductase
A9C19_RS16430	COG2197	response regulator
A9C19_RS16435	COG4585	Histidine kinase
A9C19_RS16435	COG2203	Gaf domain
A9C19_RS16445	COG1131	(ABC) transporter
A9C19_RS16460	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A9C19_RS16465	COG3153	acetyltransferase
A9C19_RS16465	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A9C19_RS16470	COG0517	IMP dehydrogenase activity
A9C19_RS16490	COG0564	pseudouridine synthase activity
A9C19_RS16500	COG3764	Sortase (surface protein transpeptidase)
A9C19_RS16505	COG2249	NAD(P)H dehydrogenase (quinone) activity
A9C19_RS16525	COG4191	Histidine kinase
A9C19_RS16530	COG4607	ABC-type enterochelin transport system periplasmic component
A9C19_RS16535	COG4604	ABC transporter, ATP-binding protein
A9C19_RS16540	COG4605	iron ion homeostasis
A9C19_RS16560	COG3250	beta-galactosidase activity
A9C19_RS16580	COG2972	Histidine kinase
A9C19_RS16585	COG4753	response regulator
A9C19_RS16585	COG2207	Transcriptional regulator
A9C19_RS16605	COG2766	serine protein kinase
A9C19_RS16610	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
A9C19_RS16620	COG0300	oxidoreductase activity
A9C19_RS16630	COG3382	B3 4 domain protein
A9C19_RS16650	COG4191	Histidine kinase
A9C19_RS16655	COG1309	transcriptional regulator
A9C19_RS16660	COG0477	Major facilitator Superfamily
A9C19_RS16670	COG1366	Belongs to the anti-sigma-factor antagonist family
A9C19_RS16680	COG4191	Histidine kinase
A9C19_RS16725	COG5444	nuclease activity
A9C19_RS16780	COG3507	Belongs to the glycosyl hydrolase 43 family
A9C19_RS16780	COG2382	esterase
A9C19_RS16780	COG3693	PFAM glycoside hydrolase, family 10
A9C19_RS16785	COG0667	Aldo Keto reductase
A9C19_RS16790	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
A9C19_RS16795	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
A9C19_RS16800	COG1079	Belongs to the binding-protein-dependent transport system permease family
A9C19_RS16805	COG4603	Belongs to the binding-protein-dependent transport system permease family
A9C19_RS16810	COG3845	ABC transporter
A9C19_RS16870	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
A9C19_RS16980	COG0735	belongs to the Fur family
A9C19_RS16985	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A9C19_RS16995	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A9C19_RS17035	COG4555	ABC transporter
A9C19_RS17040	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
A9C19_RS17045	COG4129	membrane
A9C19_RS17060	COG1132	(ABC) transporter
A9C19_RS17065	COG3557	Belongs to the UPF0374 family
A9C19_RS17080	COG1028	Short-chain dehydrogenase reductase Sdr
A9C19_RS17090	COG1194	a g-specific adenine glycosylase
A9C19_RS17095	COG1988	membrane-bound metal-dependent
A9C19_RS17125	COG1090	epimerase
A9C19_RS17190	COG0513	Belongs to the DEAD box helicase family
A9C19_RS17200	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
A9C19_RS17210	COG0673	inositol 2-dehydrogenase activity
A9C19_RS17215	COG0673	inositol 2-dehydrogenase activity
A9C19_RS17225	COG1609	Transcriptional regulator
A9C19_RS17235	COG1028	Short-chain dehydrogenase reductase Sdr
A9C19_RS17245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A9C19_RS17255	COG0559	Belongs to the binding-protein-dependent transport system permease family
A9C19_RS17275	COG2909	trisaccharide binding
A9C19_RS17285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A9C19_RS17290	COG1511	domain protein
A9C19_RS17295	COG1309	transcriptional regulator
A9C19_RS17310	COG4990	cell redox homeostasis
A9C19_RS17350	COG0142	geranyltranstransferase activity
A9C19_RS17355	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
A9C19_RS17360	COG2311	Membrane
A9C19_RS17380	COG4807	Protein conserved in bacteria
A9C19_RS17385	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
A9C19_RS17405	COG0514	ATP-dependent DNA helicase (RecQ)
A9C19_RS17420	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A9C19_RS17425	COG1012	belongs to the aldehyde dehydrogenase family
A9C19_RS17430	COG3835	regulator
A9C19_RS17450	COG0167	dihydroorotate dehydrogenase activity
A9C19_RS17460	COG0745	RESPONSE REGULATOR receiver
A9C19_RS17465	COG2205	protein histidine kinase activity
A9C19_RS17470	COG1136	(ABC) transporter
A9C19_RS17475	COG0577	efflux transmembrane transporter activity
A9C19_RS17480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A9C19_RS17510	COG0488	(ABC) transporter
A9C19_RS17535	COG1671	Belongs to the UPF0178 family
A9C19_RS17560	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A9C19_RS17565	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
A9C19_RS17580	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A9C19_RS17595	COG0535	radical SAM domain protein
A9C19_RS17600	COG0668	transmembrane transport
A9C19_RS17610	COG2364	Membrane
A9C19_RS17615	COG0387	Pfam Sodium calcium exchanger
A9C19_RS17620	COG3871	stress protein (general stress protein 26)
A9C19_RS17630	COG0477	Major facilitator Superfamily
A9C19_RS17650	COG1295	ribonuclease BN
A9C19_RS17660	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A9C19_RS17665	COG4840	Belongs to the UPF0435 family
A9C19_RS17670	COG0693	protein deglycase activity
A9C19_RS17675	COG1073	alpha beta
A9C19_RS17690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A9C19_RS17690	COG1263	PTS System
A9C19_RS17695	COG1115	amino acid carrier protein
A9C19_RS17705	COG0840	transmembrane signaling receptor activity
A9C19_RS17720	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
A9C19_RS17730	COG1994	Peptidase M50
A9C19_RS17735	COG0488	(ABC) transporter
A9C19_RS17740	COG0840	transmembrane signaling receptor activity
A9C19_RS17745	COG1725	Transcriptional regulator
A9C19_RS17750	COG1131	(ABC) transporter
A9C19_RS17760	COG1115	amino acid carrier protein
A9C19_RS17765	COG0584	glycerophosphoryl diester phosphodiesterase
A9C19_RS17780	COG1175	transmembrane transport
A9C19_RS17785	COG3842	ATPase activity
A9C19_RS17800	COG1132	(ABC) transporter
A9C19_RS17805	COG1132	(ABC) transporter
A9C19_RS17825	COG2223	nitrite transmembrane transporter activity
A9C19_RS17830	COG1388	LysM domain
A9C19_RS17830	COG3584	3D domain protein
A9C19_RS17835	COG2205	protein histidine kinase activity
A9C19_RS17880	COG0527	aspartate kinase activity
A9C19_RS17885	COG1172	Belongs to the binding-protein-dependent transport system permease family
A9C19_RS17890	COG1129	ABC transporter
A9C19_RS17910	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A9C19_RS17930	COG4152	abc transporter atp-binding protein
A9C19_RS17950	COG0142	geranyltranstransferase activity
A9C19_RS17955	COG4585	Histidine kinase
A9C19_RS17960	COG2197	response regulator
A9C19_RS17990	COG0166	Belongs to the GPI family
A9C19_RS17995	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A9C19_RS17995	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A9C19_RS17995	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A9C19_RS18010	COG3711	transcriptional antiterminator
A9C19_RS18010	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A9C19_RS18015	COG1349	DNA-binding transcription factor activity
A9C19_RS18020	COG0561	phosphatase activity
A9C19_RS18030	COG0697	spore germination
A9C19_RS18035	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
A9C19_RS18050	COG5582	Belongs to the UPF0302 family
A9C19_RS18060	COG2124	cytochrome p450
A9C19_RS18070	COG0415	Belongs to the DNA photolyase family
A9C19_RS18075	COG0737	Belongs to the 5'-nucleotidase family
A9C19_RS18090	COG0733	neurotransmitter:sodium symporter activity
A9C19_RS18105	COG3844	kynureninase activity
A9C19_RS18120	COG1595	DNA-templated transcription, initiation
A9C19_RS18125	COG1073	alpha beta
A9C19_RS18135	COG0840	transmembrane signaling receptor activity
A9C19_RS18175	COG2508	Transcriptional regulator
A9C19_RS18205	COG1979	alcohol dehydrogenase
A9C19_RS18210	COG0626	cystathionine gamma-synthase activity
A9C19_RS18220	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A9C19_RS18270	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A9C19_RS18275	COG1597	lipid kinase activity
A9C19_RS18285	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
A9C19_RS18290	COG0582	viral genome integration into host DNA
A9C19_RS18310	COG0154	amidase activity
A9C19_RS18315	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A9C19_RS18320	COG1082	Xylose isomerase domain protein TIM barrel
A9C19_RS18330	COG0318	PFAM AMP-dependent synthetase and ligase
A9C19_RS18360	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A9C19_RS18370	COG1012	belongs to the aldehyde dehydrogenase family
A9C19_RS18375	COG4851	CamS sex pheromone cAM373 precursor
A9C19_RS18380	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
A9C19_RS18385	COG0210	DNA helicase
A9C19_RS18390	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
A9C19_RS18395	COG1714	RDD family
A9C19_RS18400	COG4496	protein, YerC YecD
A9C19_RS18405	COG1470	cell adhesion involved in biofilm formation
A9C19_RS18410	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
A9C19_RS18420	COG0151	Belongs to the GarS family
A9C19_RS18425	COG0138	bifunctional purine biosynthesis protein purh
A9C19_RS18430	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
A9C19_RS18435	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
A9C19_RS18440	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
A9C19_RS18445	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A9C19_RS18450	COG0047	phosphoribosylformylglycinamidine synthase activity
A9C19_RS18455	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A9C19_RS18465	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A9C19_RS18470	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
A9C19_RS18475	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A9C19_RS18485	COG0346	lactoylglutathione lyase activity
A9C19_RS18505	COG4191	Histidine kinase
A9C19_RS18530	COG0456	acetyltransferase
A9C19_RS18560	COG2252	PERMEase
A9C19_RS18565	COG0519	Catalyzes the synthesis of GMP from XMP
A9C19_RS18565	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A9C19_RS18570	COG1305	Transglutaminase-like
A9C19_RS18575	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
A9C19_RS18580	COG0714	Associated with various cellular activities
A9C19_RS18600	COG1357	PFAM Pentapeptide repeats (8 copies)
A9C19_RS18605	COG1051	belongs to the nudix hydrolase family
A9C19_RS18615	COG1316	TRANSCRIPTIONal
A9C19_RS18620	COG1595	DNA-templated transcription, initiation
A9C19_RS18670	COG4191	Histidine kinase
A9C19_RS18685	COG1595	DNA-templated transcription, initiation
A9C19_RS18700	COG1136	(ABC) transporter
A9C19_RS18700	COG0577	efflux transmembrane transporter activity
A9C19_RS18730	COG2130	NADP-dependent
A9C19_RS18775	COG3378	Phage plasmid primase P4 family
A9C19_RS18795	COG0582	viral genome integration into host DNA
A9C19_RS18800	COG0459	protein refolding
A9C19_RS18810	COG1266	CAAX protease self-immunity
A9C19_RS18820	COG0805	protein transport
A9C19_RS18825	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A9C19_RS18830	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
A9C19_RS18835	COG0315	cyclic pyranopterin monophosphate synthase activity
A9C19_RS18840	COG0488	(ABC) transporter
A9C19_RS18850	COG0456	acetyltransferase
A9C19_RS18855	COG1214	PFAM Peptidase M22, glycoprotease
A9C19_RS18860	COG0802	atpase or kinase
A9C19_RS18865	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
A9C19_RS18950	COG3091	SprT-like family
A9C19_RS18955	COG2183	response to ionizing radiation
A9C19_RS18960	COG2208	phosphoserine phosphatase activity
A9C19_RS18965	COG1191	sigma factor activity
A9C19_RS18975	COG1366	Belongs to the anti-sigma-factor antagonist family
A9C19_RS18980	COG2208	phosphoserine phosphatase activity
A9C19_RS18985	COG2172	sigma factor antagonist activity
A9C19_RS18990	COG1366	Belongs to the anti-sigma-factor antagonist family
A9C19_RS18995	COG1366	Belongs to the anti-sigma-factor antagonist family
A9C19_RS19000	COG2337	Toxic component of a toxin-antitoxin (TA) module
A9C19_RS19005	COG0864	Transcriptional regulator
A9C19_RS19010	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A9C19_RS19020	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
A9C19_RS19030	COG0736	holo-[acyl-carrier-protein] synthase activity
A9C19_RS19035	COG0705	Rhomboid family
A9C19_RS19040	COG3428	Bacterial PH domain
A9C19_RS19045	COG3402	PFAM membrane-flanked domain
A9C19_RS19050	COG4294	response to UV
A9C19_RS19055	COG0513	Belongs to the DEAD box helicase family
A9C19_RS19065	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A9C19_RS19070	COG1181	Belongs to the D-alanine--D-alanine ligase family
A9C19_RS19085	COG0628	permease
A9C19_RS19090	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
A9C19_RS19095	COG2226	methyltransferase
A9C19_RS19100	COG1113	amino acid transport
A9C19_RS19105	COG2318	DinB family
A9C19_RS19120	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A9C19_RS19120	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A9C19_RS19125	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A9C19_RS19125	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A9C19_RS19130	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A9C19_RS19170	COG0463	Glycosyl transferase, family 2
A9C19_RS19170	COG0457	Tetratricopeptide repeat
A9C19_RS19185	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
A9C19_RS19195	COG0386	Belongs to the glutathione peroxidase family
A9C19_RS19205	COG1595	DNA-templated transcription, initiation
A9C19_RS19215	COG5504	Zn-dependent protease
A9C19_RS19235	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A9C19_RS19240	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A9C19_RS19245	COG4856	YbbR-like protein
A9C19_RS19250	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
A9C19_RS19255	COG5662	AntiSigma factor
A9C19_RS19260	COG1595	DNA-templated transcription, initiation
A9C19_RS19335	COG0726	polysaccharide deacetylase
A9C19_RS19340	COG2194	sulfuric ester hydrolase activity
A9C19_RS19350	COG0489	protein tyrosine kinase activity
A9C19_RS19355	COG0860	N-Acetylmuramoyl-L-alanine amidase
A9C19_RS19365	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A9C19_RS19400	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
A9C19_RS19435	COG0582	viral genome integration into host DNA
A9C19_RS19440	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A9C19_RS19445	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
A9C19_RS19450	COG0101	tRNA pseudouridine synthase activity
A9C19_RS19455	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A9C19_RS19460	COG1122	ATPase activity
A9C19_RS19465	COG1122	ATPase activity
A9C19_RS19470	COG0203	ribosomal protein L17
A9C19_RS19475	COG0202	RNA polymerase activity
A9C19_RS19485	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A9C19_RS19490	COG0257	Belongs to the bacterial ribosomal protein bL36 family
A9C19_RS19495	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
A9C19_RS19500	COG0024	Methionine aminopeptidase
A9C19_RS19505	COG0563	adenylate kinase activity
A9C19_RS19510	COG0201	protein transport
A9C19_RS19515	COG0200	Binds to the 23S rRNA
A9C19_RS19520	COG1841	ribosomal large subunit assembly
A9C19_RS19525	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
A9C19_RS19530	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
A9C19_RS19540	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
A9C19_RS19545	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
A9C19_RS19555	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
A9C19_RS19560	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
A9C19_RS19565	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
A9C19_RS19570	COG0255	Belongs to the universal ribosomal protein uL29 family
A9C19_RS19580	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
A9C19_RS19585	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
A9C19_RS19590	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
A9C19_RS19595	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A9C19_RS19600	COG0089	rRNA binding
A9C19_RS19605	COG0088	Forms part of the polypeptide exit tunnel
A9C19_RS19610	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
A9C19_RS19615	COG0051	transcription antitermination factor activity, RNA binding
A9C19_RS19620	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
A9C19_RS19625	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
A9C19_RS19630	COG0049	tRNA binding
A9C19_RS19640	COG1358	cellular component organization or biogenesis
A9C19_RS19645	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
A9C19_RS19650	COG0085	RNA polymerase activity
A9C19_RS19655	COG2813	Specifically methylates the guanine in position
A9C19_RS19660	COG0222	ribosome binding
A9C19_RS19665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
A9C19_RS19670	COG0081	regulation of translation
A9C19_RS19675	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
A9C19_RS19680	COG0250	Participates in transcription elongation, termination and antitermination
A9C19_RS19685	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A9C19_RS19690	COG0267	Belongs to the bacterial ribosomal protein bL33 family
A9C19_RS19700	COG3688	RNA-binding protein containing a PIN domain
A9C19_RS19705	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A9C19_RS19715	COG0215	cysteine-tRNA ligase activity
A9C19_RS19720	COG1045	serine acetyltransferase
A9C19_RS19725	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A9C19_RS19730	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
A9C19_RS19740	COG4956	integral membrane protein (PIN domain superfamily)
A9C19_RS19745	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
A9C19_RS19750	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
A9C19_RS19755	COG0542	response to heat
A9C19_RS19760	COG3869	Catalyzes the specific phosphorylation of arginine residues in
A9C19_RS19765	COG3880	PFAM UvrB UvrC protein
A9C19_RS19775	COG1285	pathogenesis
A9C19_RS19855	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
A9C19_RS19860	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A9C19_RS19865	COG1396	sequence-specific DNA binding
A9C19_RS19870	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A9C19_RS19875	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
A9C19_RS19880	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A9C19_RS19885	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A9C19_RS19890	COG0512	Glutamine amidotransferase of anthranilate synthase
A9C19_RS19895	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A9C19_RS19900	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A9C19_RS19905	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A9C19_RS19910	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
A9C19_RS19915	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
A9C19_RS19920	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A9C19_RS19925	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
A9C19_RS19930	COG0037	tRNA processing
A9C19_RS19935	COG0515	serine threonine protein kinase
A9C19_RS19940	COG2304	oxidoreductase activity
A9C19_RS19945	COG2208	phosphoserine phosphatase activity
A9C19_RS19960	COG1098	S1 RNA binding domain
A9C19_RS19965	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
A9C19_RS19980	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A9C19_RS19985	COG3956	TIGRFAM MazG family protein
A9C19_RS19990	COG2244	polysaccharide biosynthetic process
A9C19_RS19995	COG2002	toxin-antitoxin pair type II binding
A9C19_RS20000	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A9C19_RS20010	COG0193	aminoacyl-tRNA hydrolase activity
A9C19_RS20015	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
A9C19_RS20020	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A9C19_RS20025	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
A9C19_RS20030	COG2088	sporulation resulting in formation of a cellular spore
A9C19_RS20035	COG0251	oxidation-reduction process
A9C19_RS20040	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A9C19_RS20045	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
A9C19_RS20055	COG4466	Protein conserved in bacteria
A9C19_RS20065	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
A9C19_RS20075	COG3583	domain protein
A9C19_RS20075	COG3584	3D domain protein
A9C19_RS20080	COG0084	hydrolase, TatD family'
A9C19_RS20090	COG2002	toxin-antitoxin pair type II binding
A9C19_RS20095	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
A9C19_RS20105	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
A9C19_RS20110	COG4467	Involved in initiation control of chromosome replication
A9C19_RS20115	COG1774	PSP1 C-terminal conserved region
A9C19_RS20120	COG0470	DNA polymerase III
A9C19_RS20125	COG1728	Protein conserved in bacteria
A9C19_RS20130	COG3870	Protein conserved in bacteria
A9C19_RS20135	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
A9C19_RS20140	COG1982	Orn Lys Arg decarboxylase major
A9C19_RS20185	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
A9C19_RS20190	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
A9C19_RS20195	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A9C19_RS20205	COG0590	tRNA wobble adenosine to inosine editing
A9C19_RS20210	COG1335	isochorismatase
A9C19_RS20215	COG3858	chitin binding
A9C19_RS20215	COG1388	LysM domain
A9C19_RS20220	COG1428	Deoxynucleoside kinase
A9C19_RS20225	COG1428	Deoxynucleoside kinase
A9C19_RS20235	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
A9C19_RS20240	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
A9C19_RS20250	COG1686	Belongs to the peptidase S11 family
A9C19_RS20255	COG0516	GMP reductase activity
A9C19_RS20255	COG0517	IMP dehydrogenase activity
A9C19_RS20295	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
A9C19_RS20300	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A9C19_RS20305	COG0187	DNA topoisomerase II activity
A9C19_RS20315	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
A9C19_RS20320	COG2501	S4 domain
A9C19_RS20325	COG0592	DNA-directed DNA polymerase activity
A9C19_RS20330	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
A9C19_RS20335	COG0230	Belongs to the bacterial ribosomal protein bL34 family
A9C19_RS20340	COG0594	ribonuclease P activity
A9C19_RS20345	COG0706	membrane insertase activity
A9C19_RS20350	COG1847	R3H domain protein
A9C19_RS20365	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
A9C19_RS20370	COG0445	tRNA wobble uridine modification
A9C19_RS20375	COG0357	Ribosomal RNA small subunit methyltransferase G
A9C19_RS20380	COG1475	DNA binding
A9C19_RS20385	COG1192	Involved in chromosome partitioning
A9C19_RS20390	COG1475	DNA binding
A9C19_RS20395	COG1811	Na channel or pump
A9C19_RS20405	COG3949	Membrane
A9C19_RS20410	COG0668	transmembrane transport
A9C19_RS20415	COG4481	Protein conserved in bacteria
A9C19_RS20420	COG0243	molybdopterin cofactor binding
A9C19_RS20425	COG0012	GTP binding
A9C19_RS20430	COG0360	Binds together with S18 to 16S ribosomal RNA
A9C19_RS20435	COG0629	single-stranded DNA binding
A9C19_RS20440	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
A9C19_RS20445	COG4241	membrane
A9C19_RS20450	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
A9C19_RS20455	COG0359	binds to the 23S rRNA
A9C19_RS20460	COG0305	Participates in initiation and elongation during chromosome replication
A9C19_RS20465	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
A9C19_RS20495	COG0745	RESPONSE REGULATOR receiver
A9C19_RS20500	COG5002	protein histidine kinase activity
A9C19_RS20505	COG4863	YycH protein
A9C19_RS20510	COG4853	Protein conserved in bacteria
A9C19_RS20515	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A9C19_RS20520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A9C19_RS20530	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
A9C19_RS20535	COG0840	transmembrane signaling receptor activity
A9C19_RS20575	COG2070	2-Nitropropane dioxygenase
A9C19_RS20585	COG3403	YqcI/YcgG family
A9C19_RS20605	COG0745	RESPONSE REGULATOR receiver
A9C19_RS20610	COG5002	protein histidine kinase activity
A9C19_RS20640	COG3706	GGDEF domain
A9C19_RS20645	COG1120	ATPase activity
A9C19_RS20650	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A9C19_RS20655	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A9C19_RS20660	COG4607	ABC-type enterochelin transport system periplasmic component
A9C19_RS20685	COG1404	Belongs to the peptidase S8 family
A9C19_RS20710	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A9C19_RS20715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A9C19_RS20720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A9C19_RS20725	COG1120	ATPase activity
A9C19_RS20730	COG3706	GGDEF domain
A9C19_RS20735	COG3290	protein histidine kinase activity
A9C19_RS20740	COG2207	Transcriptional regulator
A9C19_RS20740	COG0662	Cupin 2, conserved barrel domain protein
A9C19_RS20745	COG0697	spore germination
A9C19_RS20750	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A9C19_RS20760	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
A9C19_RS20765	COG0778	Nitroreductase
A9C19_RS20770	COG3634	alkyl hydroperoxide reductase activity
A9C19_RS20775	COG0450	alkyl hydroperoxide reductase
A9C19_RS20790	COG0753	catalase activity
A9C19_RS20795	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A9C19_RS20800	COG1115	amino acid carrier protein
A9C19_RS20805	COG2329	Antibiotic biosynthesis monooxygenase
A9C19_RS20815	COG1902	pentaerythritol trinitrate reductase activity
A9C19_RS20825	COG2364	Membrane
A9C19_RS20830	COG1174	glycine betaine transport
A9C19_RS20835	COG1125	glycine betaine transport
A9C19_RS20835	COG0517	IMP dehydrogenase activity
A9C19_RS20855	COG0840	transmembrane signaling receptor activity
A9C19_RS20865	COG2235	arginine
A9C19_RS20870	COG3403	YqcI/YcgG family
A9C19_RS20875	COG1280	lysine exporter protein (LysE YggA)
A9C19_RS20880	COG2391	methyltransferase activity
A9C19_RS20885	COG0492	ferredoxin-NADP+ reductase activity
A9C19_RS20890	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A9C19_RS20900	COG1028	Short-chain dehydrogenase reductase Sdr
A9C19_RS20905	COG1132	(ABC) transporter
A9C19_RS20910	COG1132	(ABC) transporter
A9C19_RS20915	COG2323	membrane
A9C19_RS20920	COG2270	Major facilitator Superfamily
A9C19_RS20930	COG4842	Belongs to the WXG100 family
A9C19_RS20935	COG5417	Belongs to the EsaB family
A9C19_RS20940	COG4499	WXG100 protein secretion system (Wss), protein YukC
A9C19_RS20945	COG1674	ftsk spoiiie
A9C19_RS20945	COG0433	COG0433 Predicted ATPase
A9C19_RS20950	COG1511	domain protein
A9C19_RS20980	COG0840	transmembrane signaling receptor activity
A9C19_RS20980	COG5278	phosphoserine phosphatase activity
A9C19_RS20985	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A9C19_RS21015	COG2195	Cleaves the N-terminal amino acid of tripeptides
A9C19_RS21095	COG5278	phosphoserine phosphatase activity
A9C19_RS21095	COG0840	transmembrane signaling receptor activity