locus-tag	class	description
K8M08_RS00005	COG1012	belongs to the aldehyde dehydrogenase family
K8M08_RS00010	COG1115	amino acid carrier protein
K8M08_RS00015	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
K8M08_RS00030	COG3397	chitin binding
K8M08_RS00055	COG4637	Psort location Cytoplasmic, score
K8M08_RS00085	COG0514	ATP-dependent DNA helicase (RecQ)
K8M08_RS00105	COG3973	AAA domain
K8M08_RS00155	COG0658	competence protein
K8M08_RS00155	COG2333	competence protein COMEC
K8M08_RS00165	COG2315	Protein conserved in bacteria
K8M08_RS00170	COG2226	methyltransferase
K8M08_RS00175	COG2205	protein histidine kinase activity
K8M08_RS00195	COG1819	glycosyl
K8M08_RS00200	COG3397	chitin binding
K8M08_RS00205	COG2153	protein acetylation
K8M08_RS00235	COG0517	IMP dehydrogenase activity
K8M08_RS00235	COG4175	Glycine betaine
K8M08_RS00240	COG4176	ABC-type proline glycine betaine transport system permease component
K8M08_RS00280	COG0456	acetyltransferase
K8M08_RS00280	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
K8M08_RS00285	COG1028	Short-chain dehydrogenase reductase Sdr
K8M08_RS00295	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K8M08_RS00300	COG0022	dehydrogenase e1 component
K8M08_RS00305	COG0508	dehydrogenase complex catalyzes the overall conversion of
K8M08_RS00310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K8M08_RS00330	COG1349	DNA-binding transcription factor activity
K8M08_RS00345	COG3284	Transcriptional regulator
K8M08_RS00365	COG1309	transcriptional regulator
K8M08_RS00405	COG2959	enzyme of heme biosynthesis
K8M08_RS00420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8M08_RS00460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8M08_RS00465	COG0697	spore germination
K8M08_RS00475	COG0201	protein transport
K8M08_RS00485	COG3227	Zinc metalloprotease (Elastase)
K8M08_RS00490	COG1523	belongs to the glycosyl hydrolase 13 family
K8M08_RS00510	COG1011	Hydrolase
K8M08_RS00535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K8M08_RS00575	COG0322	excinuclease ABC activity
K8M08_RS00615	COG4667	esterase of the alpha-beta hydrolase superfamily
K8M08_RS00635	COG3878	Protein conserved in bacteria
K8M08_RS00670	COG0592	DNA-directed DNA polymerase activity
K8M08_RS00675	COG2816	NAD+ diphosphatase activity
K8M08_RS00690	COG2223	nitrite transmembrane transporter activity
K8M08_RS00700	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K8M08_RS00735	COG0697	spore germination
K8M08_RS00740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8M08_RS00755	COG0584	glycerophosphoryl diester phosphodiesterase
K8M08_RS00770	COG2814	Major facilitator Superfamily
K8M08_RS00780	COG0693	protein deglycase activity
K8M08_RS00830	COG1028	Short-chain dehydrogenase reductase Sdr
K8M08_RS00840	COG0768	penicillin binding
K8M08_RS00845	COG0671	phosphoesterase, PA-phosphatase related
K8M08_RS00850	COG0604	alcohol dehydrogenase
K8M08_RS00855	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
K8M08_RS00865	COG2205	protein histidine kinase activity
K8M08_RS00890	COG1794	racemase activity, acting on amino acids and derivatives
K8M08_RS00895	COG1819	glycosyl
K8M08_RS00905	COG5002	protein histidine kinase activity
K8M08_RS00910	COG0561	phosphatase activity
K8M08_RS00945	COG2124	cytochrome p450
K8M08_RS01065	COG0740	serine-type endopeptidase activity
K8M08_RS01075	COG4626	Terminase
K8M08_RS01075	COG1802	Transcriptional regulator
K8M08_RS01120	COG0582	viral genome integration into host DNA
K8M08_RS01140	COG0662	Cupin 2, conserved barrel domain protein
K8M08_RS01180	COG1484	DNA-dependent DNA replication
K8M08_RS01230	COG0582	viral genome integration into host DNA
K8M08_RS01260	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
K8M08_RS01270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8M08_RS01275	COG0460	homoserine dehydrogenase
K8M08_RS01295	COG0577	efflux transmembrane transporter activity
K8M08_RS01300	COG1136	(ABC) transporter
K8M08_RS01315	COG0488	(ABC) transporter
K8M08_RS01325	COG2205	protein histidine kinase activity
K8M08_RS01330	COG0745	RESPONSE REGULATOR receiver
K8M08_RS01340	COG3773	Cell wall hydrolase
K8M08_RS01355	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
K8M08_RS01360	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
K8M08_RS01365	COG2323	membrane
K8M08_RS01385	COG2368	4-hydroxyphenylacetate
K8M08_RS01395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8M08_RS01425	COG2226	methyltransferase
K8M08_RS01430	COG1733	regulation of RNA biosynthetic process
K8M08_RS01435	COG1028	Short-chain dehydrogenase reductase Sdr
K8M08_RS01460	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
K8M08_RS01475	COG3227	Zinc metalloprotease (Elastase)
K8M08_RS01495	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
K8M08_RS01520	COG1686	Belongs to the peptidase S11 family
K8M08_RS01525	COG2318	DinB family
K8M08_RS01535	COG0572	uridine kinase
K8M08_RS01555	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K8M08_RS01560	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K8M08_RS01565	COG1024	Enoyl-CoA hydratase
K8M08_RS01570	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
K8M08_RS01575	COG0511	ligase activity, forming carbon-carbon bonds
K8M08_RS01580	COG0439	Biotin carboxylase
K8M08_RS01585	COG1960	acyl-CoA dehydrogenase activity
K8M08_RS01600	COG1309	transcriptional regulator
K8M08_RS01610	COG1131	(ABC) transporter
K8M08_RS01635	COG0584	glycerophosphoryl diester phosphodiesterase
K8M08_RS01690	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8M08_RS01695	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K8M08_RS01710	COG1131	(ABC) transporter
K8M08_RS01720	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
K8M08_RS01765	COG1404	Belongs to the peptidase S8 family
K8M08_RS01770	COG2197	response regulator
K8M08_RS01775	COG4585	Histidine kinase
K8M08_RS01815	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8M08_RS01825	COG2755	lipolytic protein G-D-S-L family
K8M08_RS01825	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
K8M08_RS01835	COG3773	Cell wall hydrolase
K8M08_RS01850	COG3718	enzyme involved in inositol metabolism
K8M08_RS01880	COG0673	inositol 2-dehydrogenase activity
K8M08_RS01885	COG2814	Major facilitator Superfamily
K8M08_RS01890	COG1609	Transcriptional regulator
K8M08_RS01900	COG2367	Beta-lactamase
K8M08_RS01905	COG0768	penicillin binding
K8M08_RS01910	COG0768	penicillin binding
K8M08_RS01920	COG1595	DNA-templated transcription, initiation
K8M08_RS01925	COG0768	penicillin binding
K8M08_RS01935	COG0110	maltose O-acetyltransferase activity
K8M08_RS01945	COG2195	Cleaves the N-terminal amino acid of tripeptides
K8M08_RS01975	COG1846	Transcriptional regulator
K8M08_RS01980	COG3961	Belongs to the TPP enzyme family
K8M08_RS01990	COG0500	methyltransferase
K8M08_RS01990	COG3615	Tellurite resistance protein tehB
K8M08_RS01995	COG0577	efflux transmembrane transporter activity
K8M08_RS01995	COG1136	(ABC) transporter
K8M08_RS02010	COG1309	transcriptional regulator
K8M08_RS02045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8M08_RS02065	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
K8M08_RS02075	COG2971	BadF BadG BcrA BcrD
K8M08_RS02100	COG1649	PFAM Uncharacterised BCR, COG1649
K8M08_RS02125	COG1595	DNA-templated transcription, initiation
K8M08_RS02130	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
K8M08_RS02140	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
K8M08_RS02170	COG1396	sequence-specific DNA binding
K8M08_RS02190	COG1132	(ABC) transporter
K8M08_RS02195	COG1132	(ABC) transporter
K8M08_RS02210	COG2258	MOSC domain
K8M08_RS02215	COG0583	DNA-binding transcription factor activity
K8M08_RS02230	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
K8M08_RS02235	COG0583	DNA-binding transcription factor activity
K8M08_RS02245	COG0561	phosphatase activity
K8M08_RS02250	COG0010	Belongs to the arginase family
K8M08_RS02265	COG1278	Cold shock
K8M08_RS02275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8M08_RS02285	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
K8M08_RS02290	COG0596	Alpha beta hydrolase
K8M08_RS02315	COG1247	-acetyltransferase
K8M08_RS02345	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8M08_RS02360	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K8M08_RS02395	COG2226	methyltransferase
K8M08_RS02405	COG0028	Belongs to the TPP enzyme family
K8M08_RS02420	COG2814	Major facilitator Superfamily
K8M08_RS02425	COG0596	Alpha beta hydrolase
K8M08_RS02435	COG1136	(ABC) transporter
K8M08_RS02445	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
K8M08_RS02450	COG1187	pseudouridine synthase activity
K8M08_RS02455	COG2329	Antibiotic biosynthesis monooxygenase
K8M08_RS02480	COG1115	amino acid carrier protein
K8M08_RS02490	COG2318	DinB family
K8M08_RS02500	COG0776	regulation of translation
K8M08_RS02515	COG2814	Major facilitator Superfamily
K8M08_RS02520	COG3251	PFAM MbtH domain protein
K8M08_RS02525	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K8M08_RS02530	COG1535	isochorismatase
K8M08_RS02530	COG3433	isochorismatase activity
K8M08_RS02535	COG1021	2,3-dihydroxybenzoate-AMP ligase
K8M08_RS02540	COG1169	isochorismate synthase
K8M08_RS02545	COG1028	Short-chain dehydrogenase reductase Sdr
K8M08_RS02550	COG2223	nitrite transmembrane transporter activity
K8M08_RS02575	COG0420	3'-5' exonuclease activity
K8M08_RS02590	COG1024	Enoyl-CoA hydratase
K8M08_RS02595	COG1280	lysine exporter protein (LysE YggA)
K8M08_RS02605	COG2084	Dehydrogenase
K8M08_RS02610	COG1960	acyl-CoA dehydrogenase activity
K8M08_RS02615	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
K8M08_RS02620	COG2079	MmgE PrpD family protein
K8M08_RS02625	COG0372	Belongs to the citrate synthase family
K8M08_RS02630	COG4841	protein insertion into membrane
K8M08_RS02635	COG2814	Major facilitator Superfamily
K8M08_RS02645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8M08_RS02645	COG4499	WXG100 protein secretion system (Wss), protein YukC
K8M08_RS02665	COG1028	Short-chain dehydrogenase reductase Sdr
K8M08_RS02695	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
K8M08_RS02730	COG1595	DNA-templated transcription, initiation
K8M08_RS02785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8M08_RS02790	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
K8M08_RS02795	COG0671	phosphoesterase, PA-phosphatase related
K8M08_RS02800	COG4326	sporulation control protein
K8M08_RS02805	COG3064	Membrane
K8M08_RS02805	COG4991	sh3 domain protein
K8M08_RS02805	COG0515	serine threonine protein kinase
K8M08_RS02840	COG1509	lysine 2,3-aminomutase activity
K8M08_RS02845	COG3829	transcription factor binding
K8M08_RS02850	COG0456	acetyltransferase
K8M08_RS02855	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K8M08_RS02860	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
K8M08_RS02865	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
K8M08_RS02870	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K8M08_RS02885	COG5506	Protein of unknown function (DUF1694)
K8M08_RS02890	COG1012	belongs to the aldehyde dehydrogenase family
K8M08_RS02895	COG1253	flavin adenine dinucleotide binding
K8M08_RS02930	COG1174	glycine betaine transport
K8M08_RS02935	COG0517	IMP dehydrogenase activity
K8M08_RS02935	COG1125	glycine betaine transport
K8M08_RS03005	COG1064	alcohol dehydrogenase
K8M08_RS03015	COG2197	response regulator
K8M08_RS03020	COG2203	Gaf domain
K8M08_RS03020	COG4585	Histidine kinase
K8M08_RS03025	COG0668	transmembrane transport
K8M08_RS03030	COG0071	Belongs to the small heat shock protein (HSP20) family
K8M08_RS03035	COG1051	belongs to the nudix hydrolase family
K8M08_RS03040	COG1335	isochorismatase
K8M08_RS03055	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K8M08_RS03060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8M08_RS03080	COG0367	asparagine synthase
K8M08_RS03085	COG0071	Belongs to the small heat shock protein (HSP20) family
K8M08_RS03090	COG1999	signal sequence binding
K8M08_RS03095	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
K8M08_RS03100	COG1307	EDD domain protein, DegV family
K8M08_RS03110	COG0805	protein transport
K8M08_RS03120	COG1272	protein, Hemolysin III
K8M08_RS03125	COG0204	Acyl-transferase
K8M08_RS03135	COG0768	penicillin binding
K8M08_RS03150	COG3250	beta-galactosidase activity
K8M08_RS03155	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K8M08_RS03170	COG0546	phosphoglycolate phosphatase activity
K8M08_RS03180	COG4473	ABC transporter
K8M08_RS03185	COG1131	(ABC) transporter
K8M08_RS03195	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
K8M08_RS03200	COG0456	acetyltransferase
K8M08_RS03210	COG1794	racemase activity, acting on amino acids and derivatives
K8M08_RS03215	COG1454	alcohol dehydrogenase
K8M08_RS03220	COG2610	gluconate transmembrane transporter activity
K8M08_RS03245	COG0733	neurotransmitter:sodium symporter activity
K8M08_RS03305	COG1674	ftsk spoiiie
K8M08_RS03325	COG0017	Asparaginyl-tRNA synthetase
K8M08_RS03330	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
K8M08_RS03375	COG2136	Putative SAM-dependent methyltransferase
K8M08_RS03375	COG2521	methyltransferase
K8M08_RS03390	COG1413	lyase activity
K8M08_RS03395	COG0629	single-stranded DNA binding
K8M08_RS03410	COG0488	(ABC) transporter
K8M08_RS03415	COG1418	mRNA catabolic process
K8M08_RS03440	COG2359	stage V sporulation protein S
K8M08_RS03465	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
K8M08_RS03470	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K8M08_RS03475	COG2146	nitrite reductase [NAD(P)H] activity
K8M08_RS03480	COG1587	Uroporphyrinogen-III synthase
K8M08_RS03480	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
K8M08_RS03490	COG1648	precorrin-2 dehydrogenase activity
K8M08_RS03505	COG2223	nitrite transmembrane transporter activity
K8M08_RS03515	COG0314	molybdopterin synthase activity
K8M08_RS03520	COG0303	'Molybdopterin
K8M08_RS03525	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K8M08_RS03530	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K8M08_RS03535	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K8M08_RS03540	COG2181	nitrate reductase activity
K8M08_RS03545	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
K8M08_RS03550	COG1140	nitrate reductase beta subunit
K8M08_RS03555	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
K8M08_RS03560	COG0714	Associated with various cellular activities
K8M08_RS03565	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
K8M08_RS03570	COG1305	Transglutaminase-like
K8M08_RS03575	COG0386	Belongs to the glutathione peroxidase family
K8M08_RS03605	COG1595	DNA-templated transcription, initiation
K8M08_RS03610	COG0604	alcohol dehydrogenase
K8M08_RS03620	COG0346	lactoylglutathione lyase activity
K8M08_RS03640	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
K8M08_RS03665	COG3874	Sporulation protein YtfJ
K8M08_RS03705	COG0456	acetyltransferase
K8M08_RS03735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8M08_RS03740	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8M08_RS03745	COG1819	glycosyl
K8M08_RS03760	COG4106	trans-aconitate 2-methyltransferase activity
K8M08_RS03765	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K8M08_RS03775	COG0561	phosphatase activity
K8M08_RS03800	COG0154	amidase activity
K8M08_RS03805	COG0494	nUDIX hydrolase
K8M08_RS03810	COG1876	peptidase activity
K8M08_RS03820	COG0860	N-Acetylmuramoyl-L-alanine amidase
K8M08_RS03840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K8M08_RS03845	COG1114	Component of the transport system for branched-chain amino acids
K8M08_RS03860	COG1253	flavin adenine dinucleotide binding
K8M08_RS03865	COG2839	Protein conserved in bacteria
K8M08_RS03870	COG0702	epimerase
K8M08_RS03885	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K8M08_RS03895	COG1607	acyl-coa hydrolase
K8M08_RS03900	COG3689	TIGRFAM TIGR03943 family protein
K8M08_RS03905	COG0701	Predicted permease
K8M08_RS03915	COG2244	polysaccharide biosynthetic process
K8M08_RS03920	COG0586	Pfam SNARE associated Golgi protein
K8M08_RS03925	COG1051	belongs to the nudix hydrolase family
K8M08_RS03930	COG5337	Spore coat protein CotH
K8M08_RS03940	COG0406	alpha-ribazole phosphatase activity
K8M08_RS03955	COG4166	transmembrane transport
K8M08_RS03965	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
K8M08_RS03975	COG0702	epimerase
K8M08_RS03985	COG0803	Belongs to the bacterial solute-binding protein 9 family
K8M08_RS03985	COG3443	Belongs to the bacterial solute-binding protein 9 family
K8M08_RS04000	COG0456	acetyltransferase
K8M08_RS04005	COG0523	cobalamin synthesis protein
K8M08_RS04010	COG4989	oxidoreductase activity
K8M08_RS04015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8M08_RS04020	COG1231	oxidoreductase activity
K8M08_RS04030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K8M08_RS04045	COG0783	Belongs to the Dps family
K8M08_RS04050	COG3949	Membrane
K8M08_RS04090	COG2814	Major facilitator Superfamily
K8M08_RS04095	COG0667	Aldo Keto reductase
K8M08_RS04100	COG0640	Transcriptional regulator
K8M08_RS04105	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
K8M08_RS04110	COG1404	Belongs to the peptidase S8 family
K8M08_RS04115	COG2002	toxin-antitoxin pair type II binding
K8M08_RS04120	COG0577	efflux transmembrane transporter activity
K8M08_RS04155	COG1752	Esterase of the alpha-beta hydrolase superfamily
K8M08_RS04165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8M08_RS04170	COG1279	arginine transmembrane transporter activity
K8M08_RS04175	COG2814	Major facilitator Superfamily
K8M08_RS04185	COG1082	Xylose isomerase domain protein TIM barrel
K8M08_RS04195	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K8M08_RS04215	COG1247	-acetyltransferase
K8M08_RS04220	COG1285	pathogenesis
K8M08_RS04235	COG5002	protein histidine kinase activity
K8M08_RS04240	COG0745	RESPONSE REGULATOR receiver
K8M08_RS04250	COG1316	TRANSCRIPTIONal
K8M08_RS04275	COG0460	homoserine dehydrogenase
K8M08_RS04305	COG4122	O-methyltransferase activity
K8M08_RS04310	COG0300	oxidoreductase activity
K8M08_RS04320	COG5002	protein histidine kinase activity
K8M08_RS04325	COG0745	RESPONSE REGULATOR receiver
K8M08_RS04330	COG1132	(ABC) transporter
K8M08_RS04340	COG1388	LysM domain
K8M08_RS04340	COG0791	NLP P60 protein
K8M08_RS04355	COG1686	Belongs to the peptidase S11 family
K8M08_RS04385	COG1216	Glycosyl transferase, family 2
K8M08_RS04395	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
K8M08_RS04400	COG4988	ABC transporter
K8M08_RS04405	COG1294	oxidase, subunit
K8M08_RS04410	COG1271	oxidase subunit
K8M08_RS04430	COG1942	4-Oxalocrotonate Tautomerase
K8M08_RS04440	COG0583	DNA-binding transcription factor activity
K8M08_RS04460	COG0411	ABC transporter
K8M08_RS04475	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K8M08_RS04480	COG2030	dehydratase
K8M08_RS04485	COG0318	PFAM AMP-dependent synthetase and ligase
K8M08_RS04495	COG0523	cobalamin synthesis protein
K8M08_RS04500	COG1231	oxidoreductase activity
K8M08_RS04510	COG0628	permease
K8M08_RS04520	COG0778	Nitroreductase
K8M08_RS04525	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
K8M08_RS04530	COG1959	2 iron, 2 sulfur cluster binding
K8M08_RS04535	COG0583	DNA-binding transcription factor activity
K8M08_RS04540	COG0697	spore germination
K8M08_RS04545	COG4549	nuclear export factor GLE1
K8M08_RS04550	COG1276	copper resistance
K8M08_RS04550	COG2372	response to copper ion
K8M08_RS04560	COG1114	Component of the transport system for branched-chain amino acids
K8M08_RS04585	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K8M08_RS04595	COG2132	Multicopper oxidase
K8M08_RS04600	COG0006	proline dipeptidase activity
K8M08_RS04610	COG4846	Membrane protein involved in cytochrome C biogenesis
K8M08_RS04625	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
K8M08_RS04630	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8M08_RS04640	COG2390	Transcriptional regulator
K8M08_RS04645	COG1309	transcriptional regulator
K8M08_RS04680	COG0531	amino acid
K8M08_RS04685	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
K8M08_RS04700	COG1914	H( )-stimulated, divalent metal cation uptake system
K8M08_RS04720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8M08_RS04730	COG2226	methyltransferase
K8M08_RS04745	COG4166	transmembrane transport
K8M08_RS04750	COG1073	alpha beta
K8M08_RS04770	COG0427	acetyl-CoA hydrolase
K8M08_RS04775	COG3279	Response regulator of the LytR AlgR family
K8M08_RS04785	COG3384	dioxygenase
K8M08_RS04790	COG2814	Major facilitator Superfamily
K8M08_RS04815	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
K8M08_RS04835	COG0028	Belongs to the TPP enzyme family
K8M08_RS04840	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K8M08_RS04845	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K8M08_RS04865	COG2323	membrane
K8M08_RS04870	COG5566	PFAM Mor transcription activator
K8M08_RS04880	COG0733	neurotransmitter:sodium symporter activity
K8M08_RS04885	COG2244	polysaccharide biosynthetic process
K8M08_RS04900	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K8M08_RS04905	COG2223	nitrite transmembrane transporter activity
K8M08_RS04910	COG4166	transmembrane transport
K8M08_RS04915	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
K8M08_RS04925	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K8M08_RS04930	COG0477	Major facilitator Superfamily
K8M08_RS04975	COG1051	belongs to the nudix hydrolase family
K8M08_RS05005	COG3620	sequence-specific DNA binding
K8M08_RS05020	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K8M08_RS05025	COG0784	Response regulator, receiver
K8M08_RS05030	COG4191	Histidine kinase
K8M08_RS05035	COG0281	malic enzyme
K8M08_RS05040	COG1027	Aspartate ammonia-lyase
K8M08_RS05050	COG0528	UMP kinase activity
K8M08_RS05055	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K8M08_RS05070	COG1131	(ABC) transporter
K8M08_RS05105	COG2733	membrane
K8M08_RS05145	COG3340	Belongs to the peptidase S51 family
K8M08_RS05150	COG0534	Mate efflux family protein
K8M08_RS05160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8M08_RS05170	COG0114	fumarate hydratase activity
K8M08_RS05175	COG4221	oxidoreductase activity
K8M08_RS05180	COG0789	Transcriptional regulator
K8M08_RS05185	COG1757	Na H antiporter
K8M08_RS05190	COG0438	transferase activity, transferring glycosyl groups
K8M08_RS05190	COG1216	Glycosyl transferase, family 2
K8M08_RS05200	COG0701	Predicted permease
K8M08_RS05205	COG0523	cobalamin synthesis protein
K8M08_RS05210	COG0697	spore germination
K8M08_RS05215	COG1802	Transcriptional regulator
K8M08_RS05245	COG0367	asparagine synthase
K8M08_RS05255	COG1846	Transcriptional regulator
K8M08_RS05275	COG0406	alpha-ribazole phosphatase activity
K8M08_RS05285	COG1686	Belongs to the peptidase S11 family
K8M08_RS05315	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
K8M08_RS05330	COG3842	ATPase activity
K8M08_RS05335	COG0583	DNA-binding transcription factor activity
K8M08_RS05365	COG3764	Sortase (surface protein transpeptidase)
K8M08_RS05370	COG3764	Sortase (surface protein transpeptidase)
K8M08_RS05385	COG2329	Antibiotic biosynthesis monooxygenase
K8M08_RS05430	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K8M08_RS05435	COG4786	Flagellar basal body rod
K8M08_RS05440	COG1419	protein localization to endoplasmic reticulum
K8M08_RS05445	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
K8M08_RS05450	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
K8M08_RS05460	COG1987	bacterial-type flagellum assembly
K8M08_RS05465	COG1338	Plays a role in the flagellum-specific transport system
K8M08_RS05475	COG1776	CheC inhibitor of MCP methylation
K8M08_RS05475	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K8M08_RS05480	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K8M08_RS05490	COG0741	lytic transglycosylase activity
K8M08_RS05495	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K8M08_RS05515	COG0784	Response regulator, receiver
K8M08_RS05515	COG0835	chemotaxis
K8M08_RS05550	COG1157	protein secretion by the type III secretion system
K8M08_RS05560	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K8M08_RS05565	COG1766	The M ring may be actively involved in energy transduction
K8M08_RS05575	COG1558	bacterial-type flagellum-dependent cell motility
K8M08_RS05580	COG1815	bacterial-type flagellum-dependent cell motility
K8M08_RS05595	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
K8M08_RS05600	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K8M08_RS05605	COG1256	bacterial-type flagellum assembly
K8M08_RS05625	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
K8M08_RS05640	COG1776	CheC inhibitor of MCP methylation
K8M08_RS05640	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K8M08_RS05645	COG0643	Histidine kinase
K8M08_RS05645	COG2198	Histidine kinase
K8M08_RS05650	COG2201	protein-glutamate methylesterase activity
K8M08_RS05655	COG1360	Flagellar Motor Protein
K8M08_RS05660	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
K8M08_RS05670	COG1923	regulation of RNA biosynthetic process
K8M08_RS05690	COG2814	Major facilitator Superfamily
K8M08_RS05700	COG2814	Major facilitator Superfamily
K8M08_RS05725	COG1434	Gram-negative-bacterium-type cell wall biogenesis
K8M08_RS05730	COG2323	membrane
K8M08_RS05740	COG0789	Transcriptional regulator
K8M08_RS05740	COG4978	Transcriptional regulator
K8M08_RS05745	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
K8M08_RS05750	COG0475	glutathione-regulated potassium exporter activity
K8M08_RS05760	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K8M08_RS05765	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K8M08_RS05770	COG3162	membrane
K8M08_RS05785	COG1280	lysine exporter protein (LysE YggA)
K8M08_RS05790	COG3403	YqcI/YcgG family
K8M08_RS05825	COG0328	RNA-DNA hybrid ribonuclease activity
K8M08_RS05845	COG0454	-acetyltransferase
K8M08_RS05860	COG0438	transferase activity, transferring glycosyl groups
K8M08_RS05865	COG1215	transferase activity, transferring glycosyl groups
K8M08_RS05880	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
K8M08_RS05905	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K8M08_RS05920	COG0754	glutathionylspermidine amidase activity
K8M08_RS05955	COG0456	acetyltransferase
K8M08_RS05965	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
K8M08_RS05970	COG2311	Membrane
K8M08_RS05975	COG2233	PERMEase
K8M08_RS05985	COG0024	Methionine aminopeptidase
K8M08_RS05995	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
K8M08_RS06000	COG1199	ATP-dependent helicase activity
K8M08_RS06010	COG0116	Belongs to the methyltransferase superfamily
K8M08_RS06070	COG4499	WXG100 protein secretion system (Wss), protein YukC
K8M08_RS06070	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8M08_RS06080	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
K8M08_RS06085	COG3935	DnaD domain protein
K8M08_RS06105	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
K8M08_RS06105	COG1199	ATP-dependent helicase activity
K8M08_RS06140	COG0438	transferase activity, transferring glycosyl groups
K8M08_RS06145	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
K8M08_RS06160	COG1694	Mazg nucleotide pyrophosphohydrolase
K8M08_RS06165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8M08_RS06175	COG2738	Putative neutral zinc metallopeptidase
K8M08_RS06190	COG4347	Protein of unknown function (DUF1405)
K8M08_RS06195	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
K8M08_RS06195	COG2010	Cytochrome c
K8M08_RS06200	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
K8M08_RS06220	COG0457	Tetratricopeptide repeat
K8M08_RS06245	COG0142	geranyltranstransferase activity
K8M08_RS06255	COG0142	geranyltranstransferase activity
K8M08_RS06270	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
K8M08_RS06345	COG0492	ferredoxin-NADP+ reductase activity
K8M08_RS06365	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
K8M08_RS06370	COG4862	establishment of competence for transformation
K8M08_RS06380	COG1408	metallophosphoesterase
K8M08_RS06390	COG1266	CAAX protease self-immunity
K8M08_RS06395	COG0514	ATP-dependent DNA helicase (RecQ)
K8M08_RS06405	COG1141	Ferredoxin
K8M08_RS06410	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
K8M08_RS06420	COG4942	peptidase
K8M08_RS06425	COG2096	Adenosyltransferase
K8M08_RS06430	COG5002	protein histidine kinase activity
K8M08_RS06435	COG0745	RESPONSE REGULATOR receiver
K8M08_RS06440	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K8M08_RS06445	COG1333	cytochrome c biogenesis protein
K8M08_RS06455	COG1187	pseudouridine synthase activity
K8M08_RS06460	COG0700	Nucleoside recognition
K8M08_RS06465	COG2715	membrane protein required for spore maturation
K8M08_RS06470	COG1686	Belongs to the peptidase S11 family
K8M08_RS06475	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
K8M08_RS06490	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
K8M08_RS06490	COG0392	lysyltransferase activity
K8M08_RS06505	COG5002	protein histidine kinase activity
K8M08_RS06510	COG0582	viral genome integration into host DNA
K8M08_RS06520	COG1801	Protein of unknown function DUF72
K8M08_RS06525	COG3852	Histidine kinase
K8M08_RS06540	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8M08_RS06545	COG1392	Phosphate transport regulator
K8M08_RS06550	COG0306	phosphate transporter
K8M08_RS06555	COG0730	response to heat
K8M08_RS06605	COG1114	Component of the transport system for branched-chain amino acids
K8M08_RS06615	COG2197	response regulator
K8M08_RS06620	COG4585	Histidine kinase
K8M08_RS06625	COG4758	membrane
K8M08_RS06640	COG1757	Na H antiporter
K8M08_RS06665	COG0733	neurotransmitter:sodium symporter activity
K8M08_RS06670	COG1648	precorrin-2 dehydrogenase activity
K8M08_RS06690	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K8M08_RS06695	COG0529	Catalyzes the synthesis of activated sulfate
K8M08_RS06715	COG0019	diaminopimelate decarboxylase activity
K8M08_RS06725	COG1368	sulfuric ester hydrolase activity
K8M08_RS06730	COG1183	phosphatidylcholine synthase activity
K8M08_RS06745	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
K8M08_RS06820	COG0440	acetolactate synthase activity
K8M08_RS06825	COG0028	Belongs to the TPP enzyme family
K8M08_RS06830	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K8M08_RS06850	COG3874	Sporulation protein YtfJ
K8M08_RS06855	COG4709	membrane
K8M08_RS06860	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K8M08_RS06865	COG1301	dicarboxylic acid transport
K8M08_RS06875	COG1846	Transcriptional regulator
K8M08_RS06895	COG0534	Mate efflux family protein
K8M08_RS06930	COG0716	FMN binding
K8M08_RS06965	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
K8M08_RS06970	COG2070	2-Nitropropane dioxygenase
K8M08_RS06975	COG1619	proteins homologs of microcin C7 resistance protein MccF
K8M08_RS06985	COG1335	isochorismatase
K8M08_RS06995	COG1522	sequence-specific DNA binding
K8M08_RS07005	COG1266	CAAX protease self-immunity
K8M08_RS07010	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
K8M08_RS07015	COG1131	(ABC) transporter
K8M08_RS07025	COG1131	(ABC) transporter
K8M08_RS07030	COG1725	Transcriptional regulator
K8M08_RS07035	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K8M08_RS07050	COG1780	Probably involved in ribonucleotide reductase function
K8M08_RS07080	COG4873	Protein conserved in bacteria
K8M08_RS07095	COG0720	synthase
K8M08_RS07105	COG5002	protein histidine kinase activity
K8M08_RS07115	COG2318	DinB family
K8M08_RS07125	COG1846	Transcriptional regulator
K8M08_RS07130	COG3852	Histidine kinase
K8M08_RS07140	COG2861	carbohydrate metabolic process
K8M08_RS07150	COG0235	Class ii aldolase
K8M08_RS07160	COG1349	DNA-binding transcription factor activity
K8M08_RS07185	COG3842	ATPase activity
K8M08_RS07190	COG1840	ABC-type Fe3 transport system, periplasmic component
K8M08_RS07205	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K8M08_RS07215	COG3243	poly(R)-hydroxyalkanoic acid synthase
K8M08_RS07220	COG1028	Short-chain dehydrogenase reductase Sdr
K8M08_RS07240	COG2030	dehydratase
K8M08_RS07250	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K8M08_RS07255	COG0861	Integral membrane protein TerC family
K8M08_RS07260	COG2116	formate transmembrane transporter activity
K8M08_RS07270	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
K8M08_RS07290	COG2186	Transcriptional regulator
K8M08_RS07295	COG5002	protein histidine kinase activity
K8M08_RS07300	COG0745	RESPONSE REGULATOR receiver
K8M08_RS07310	COG3835	regulator
K8M08_RS07315	COG0277	FAD linked oxidase domain protein
K8M08_RS07320	COG0247	lactate metabolic process
K8M08_RS07325	COG2340	Cysteine-rich secretory protein family
K8M08_RS07335	COG0564	pseudouridine synthase activity
K8M08_RS07345	COG2409	Drug exporters of the RND superfamily
K8M08_RS07355	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
K8M08_RS07360	COG1177	transmembrane transport
K8M08_RS07365	COG1176	ABC-type spermidine putrescine transport system, permease component I
K8M08_RS07375	COG1012	belongs to the aldehyde dehydrogenase family
K8M08_RS07390	COG1396	sequence-specific DNA binding
K8M08_RS07410	COG0681	Belongs to the peptidase S26 family
K8M08_RS07415	COG1686	Belongs to the peptidase S11 family
K8M08_RS07425	COG2226	methyltransferase
K8M08_RS07495	COG1476	TRANSCRIPTIONal
K8M08_RS07505	COG0508	dehydrogenase complex catalyzes the overall conversion of
K8M08_RS07565	COG5634	Uncharacterized conserved protein (DUF2278)
K8M08_RS07570	COG1620	l-lactate permease
K8M08_RS07605	COG0512	Glutamine amidotransferase of anthranilate synthase
K8M08_RS07605	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
K8M08_RS07615	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K8M08_RS07620	COG5492	domain, Protein
K8M08_RS07635	COG2382	esterase
K8M08_RS07645	COG2153	protein acetylation
K8M08_RS07690	COG1091	dTDP-4-dehydrorhamnose reductase activity
K8M08_RS07705	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
K8M08_RS07725	COG0457	Tetratricopeptide repeat
K8M08_RS07725	COG0463	Glycosyl transferase, family 2
K8M08_RS07745	COG1216	Glycosyl transferase, family 2
K8M08_RS07750	COG0772	Belongs to the SEDS family
K8M08_RS07765	COG0564	pseudouridine synthase activity
K8M08_RS07775	COG2357	RelA SpoT domain protein
K8M08_RS07785	COG4116	CYTH
K8M08_RS07790	COG2346	COG2346, Truncated hemoglobins
K8M08_RS07805	COG1164	Oligoendopeptidase f
K8M08_RS07815	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K8M08_RS07820	COG4862	establishment of competence for transformation
K8M08_RS07825	COG0861	Integral membrane protein TerC family
K8M08_RS07840	COG4166	transmembrane transport
K8M08_RS07845	COG0534	Mate efflux family protein
K8M08_RS07850	COG4608	Belongs to the ABC transporter superfamily
K8M08_RS07855	COG0444	Belongs to the ABC transporter superfamily
K8M08_RS07860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K8M08_RS07865	COG0601	transmembrane transport
K8M08_RS07870	COG4166	transmembrane transport
K8M08_RS07880	COG0180	Tryptophanyl-tRNA synthetase
K8M08_RS07890	COG5504	Zn-dependent protease
K8M08_RS07895	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K8M08_RS07900	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K8M08_RS07915	COG2267	carboxylic ester hydrolase activity
K8M08_RS07925	COG0542	response to heat
K8M08_RS07935	COG0561	phosphatase activity
K8M08_RS07950	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8M08_RS07960	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
K8M08_RS07965	COG2996	Protein conserved in bacteria
K8M08_RS07990	COG0004	ammonium transporteR
K8M08_RS07995	COG0753	catalase activity
K8M08_RS08005	COG0367	asparagine synthase
K8M08_RS08030	COG0179	Fumarylacetoacetate (FAA) hydrolase
K8M08_RS08090	COG0398	Pfam SNARE associated Golgi protein
K8M08_RS08100	COG4903	ComK protein
K8M08_RS08125	COG2224	Isocitrate lyase
K8M08_RS08130	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
K8M08_RS08150	COG0697	spore germination
K8M08_RS08155	COG0840	transmembrane signaling receptor activity
K8M08_RS08160	COG0501	Belongs to the peptidase M48B family
K8M08_RS08185	COG0745	RESPONSE REGULATOR receiver
K8M08_RS08190	COG2205	protein histidine kinase activity
K8M08_RS08205	COG2207	Transcriptional regulator
K8M08_RS08205	COG3708	Transcriptional regulator
K8M08_RS08210	COG1595	DNA-templated transcription, initiation
K8M08_RS08220	COG0477	Major facilitator Superfamily
K8M08_RS08230	COG1078	dGTPase activity
K8M08_RS08235	COG1408	metallophosphoesterase
K8M08_RS08240	COG1073	alpha beta
K8M08_RS08265	COG0318	PFAM AMP-dependent synthetase and ligase
K8M08_RS08275	COG0095	Lipoate-protein ligase
K8M08_RS08280	COG1234	tRNA 3'-trailer cleavage
K8M08_RS08290	COG1609	Transcriptional regulator
K8M08_RS08295	COG2378	regulation of single-species biofilm formation
K8M08_RS08320	COG1511	domain protein
K8M08_RS08325	COG1309	transcriptional regulator
K8M08_RS08350	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
K8M08_RS08365	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8M08_RS08370	COG2329	Antibiotic biosynthesis monooxygenase
K8M08_RS08375	COG3428	Bacterial PH domain
K8M08_RS08380	COG3402	PFAM membrane-flanked domain
K8M08_RS08420	COG3428	Bacterial PH domain
K8M08_RS08425	COG3402	PFAM membrane-flanked domain
K8M08_RS08435	COG1309	transcriptional regulator
K8M08_RS08450	COG4473	ABC transporter
K8M08_RS08455	COG1131	(ABC) transporter
K8M08_RS08460	COG0537	adenosine 5'-monophosphoramidase activity
K8M08_RS08465	COG4980	gas vesicle protein
K8M08_RS08485	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
K8M08_RS08490	COG3973	AAA domain
K8M08_RS08500	COG0772	Belongs to the SEDS family
K8M08_RS08510	COG1595	DNA-templated transcription, initiation
K8M08_RS08525	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
K8M08_RS08535	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
K8M08_RS08540	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
K8M08_RS08560	COG2267	carboxylic ester hydrolase activity
K8M08_RS08565	COG0457	Tetratricopeptide repeat
K8M08_RS08570	COG0346	lactoylglutathione lyase activity
K8M08_RS08575	COG0346	lactoylglutathione lyase activity
K8M08_RS08580	COG2814	Major facilitator Superfamily
K8M08_RS08585	COG1309	transcriptional regulator
K8M08_RS08595	COG4717	serine-type aminopeptidase activity
K8M08_RS08600	COG0420	3'-5' exonuclease activity
K8M08_RS08670	COG0784	Response regulator, receiver
K8M08_RS08670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8M08_RS08670	COG2198	Histidine kinase
K8M08_RS08670	COG2205	protein histidine kinase activity
K8M08_RS08675	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
K8M08_RS08680	COG2208	phosphoserine phosphatase activity
K8M08_RS08690	COG1191	sigma factor activity
K8M08_RS08715	COG3237	CsbD-like
K8M08_RS08735	COG0596	Alpha beta hydrolase
K8M08_RS08740	COG0577	efflux transmembrane transporter activity
K8M08_RS08745	COG1136	(ABC) transporter
K8M08_RS08800	COG2770	Histidine kinase
K8M08_RS08800	COG3437	response regulator, receiver
K8M08_RS08825	COG1959	2 iron, 2 sulfur cluster binding
K8M08_RS08835	COG2376	Dihydroxyacetone kinase
K8M08_RS08845	COG2376	Dihydroxyacetone kinase
K8M08_RS08865	COG1183	phosphatidylcholine synthase activity
K8M08_RS08940	COG0477	Major facilitator Superfamily
K8M08_RS08980	COG0305	Participates in initiation and elongation during chromosome replication
K8M08_RS09000	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
K8M08_RS09035	COG0494	nUDIX hydrolase
K8M08_RS09040	COG3181	Tripartite tricarboxylate transporter family receptor
K8M08_RS09045	COG4565	transcriptional regulatory protein
K8M08_RS09050	COG3290	protein histidine kinase activity
K8M08_RS09055	COG0477	Major facilitator Superfamily
K8M08_RS09070	COG3409	Peptidoglycan-binding domain 1 protein
K8M08_RS09075	COG1396	sequence-specific DNA binding
K8M08_RS09095	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8M08_RS09125	COG3409	Peptidoglycan-binding domain 1 protein
K8M08_RS09150	COG0305	Participates in initiation and elongation during chromosome replication
K8M08_RS09205	COG1363	Peptidase, m42
K8M08_RS09225	COG1024	Enoyl-CoA hydratase
K8M08_RS09245	COG4196	transglutaminase domain protein
K8M08_RS09250	COG0860	N-Acetylmuramoyl-L-alanine amidase
K8M08_RS09260	COG2244	polysaccharide biosynthetic process
K8M08_RS09265	COG0653	protein targeting
K8M08_RS09280	COG0659	secondary active sulfate transmembrane transporter activity
K8M08_RS09300	COG0635	Involved in the biosynthesis of porphyrin-containing compound
K8M08_RS09305	COG3409	Peptidoglycan-binding domain 1 protein
K8M08_RS09305	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8M08_RS09315	COG0561	phosphatase activity
K8M08_RS09330	COG3527	Alpha-acetolactate decarboxylase
K8M08_RS09335	COG0028	Belongs to the TPP enzyme family
K8M08_RS09365	COG0189	ligase activity
K8M08_RS09380	COG1126	abc transporter atp-binding protein
K8M08_RS09385	COG0765	amino acid transport
K8M08_RS09390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8M08_RS09395	COG1132	(ABC) transporter
K8M08_RS09400	COG1132	(ABC) transporter
K8M08_RS09405	COG1012	belongs to the aldehyde dehydrogenase family
K8M08_RS09415	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
K8M08_RS09420	COG0531	amino acid
K8M08_RS09430	COG0753	catalase activity
K8M08_RS09435	COG0693	protein deglycase activity
K8M08_RS09445	COG2211	Major facilitator Superfamily
K8M08_RS09450	COG4533	DNA binding
K8M08_RS09455	COG2249	NAD(P)H dehydrogenase (quinone) activity
K8M08_RS09465	COG1733	regulation of RNA biosynthetic process
K8M08_RS09470	COG2814	Major facilitator Superfamily
K8M08_RS09475	COG1309	transcriptional regulator
K8M08_RS09480	COG2076	Multidrug Resistance protein
K8M08_RS09495	COG0300	oxidoreductase activity
K8M08_RS09505	COG1522	sequence-specific DNA binding
K8M08_RS09525	COG2259	Doxx family
K8M08_RS09535	COG1263	PTS System
K8M08_RS09535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8M08_RS09545	COG1737	Transcriptional regulator
K8M08_RS09555	COG0475	glutathione-regulated potassium exporter activity
K8M08_RS09560	COG0531	amino acid
K8M08_RS09595	COG0586	Pfam SNARE associated Golgi protein
K8M08_RS09630	COG3546	catalase activity
K8M08_RS09635	COG1114	Component of the transport system for branched-chain amino acids
K8M08_RS09650	COG5522	Integral membrane protein (intg_mem_TP0381)
K8M08_RS09655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K8M08_RS09660	COG1136	(ABC) transporter
K8M08_RS09665	COG0577	efflux transmembrane transporter activity
K8M08_RS09670	COG3584	3D domain protein
K8M08_RS09670	COG1388	LysM domain
K8M08_RS09695	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K8M08_RS09700	COG1447	Phosphotransferase system cellobiose-specific component IIA
K8M08_RS09705	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
K8M08_RS09705	COG3711	transcriptional antiterminator
K8M08_RS09715	COG2814	Major facilitator Superfamily
K8M08_RS09720	COG1283	sodium-dependent phosphate transmembrane transporter activity
K8M08_RS09725	COG0604	alcohol dehydrogenase
K8M08_RS09730	COG1316	TRANSCRIPTIONal
K8M08_RS09740	COG0730	response to heat
K8M08_RS09745	COG2210	Belongs to the sulfur carrier protein TusA family
K8M08_RS09755	COG0425	Belongs to the sulfur carrier protein TusA family
K8M08_RS09755	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K8M08_RS09765	COG0425	Belongs to the sulfur carrier protein TusA family
K8M08_RS09770	COG0425	Belongs to the sulfur carrier protein TusA family
K8M08_RS09775	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K8M08_RS09775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8M08_RS09780	COG0425	Belongs to the sulfur carrier protein TusA family
K8M08_RS09780	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K8M08_RS09785	COG1937	Protein conserved in bacteria
K8M08_RS09790	COG0446	pyridine nucleotide-disulphide oxidoreductase
K8M08_RS09800	COG2719	SpoVR family
K8M08_RS09805	COG0778	Nitroreductase
K8M08_RS09845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8M08_RS09865	COG1028	Short-chain dehydrogenase reductase Sdr
K8M08_RS09870	COG2252	PERMEase
K8M08_RS09885	COG1846	Transcriptional regulator
K8M08_RS09890	COG2814	Major facilitator Superfamily
K8M08_RS09895	COG2205	protein histidine kinase activity
K8M08_RS09935	COG0351	phosphomethylpyrimidine kinase
K8M08_RS09940	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K8M08_RS09950	COG2104	thiamine diphosphate biosynthetic process
K8M08_RS09955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K8M08_RS09960	COG0352	thiamine-phosphate diphosphorylase activity
K8M08_RS09965	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K8M08_RS09970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K8M08_RS09975	COG1116	anion transmembrane transporter activity
K8M08_RS09980	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
K8M08_RS10000	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
K8M08_RS10120	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K8M08_RS10130	COG0581	inorganic phosphate transmembrane transporter activity
K8M08_RS10135	COG0573	inorganic phosphate transmembrane transporter activity
K8M08_RS10140	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
K8M08_RS10145	COG1918	ferrous iron import across plasma membrane
K8M08_RS10145	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
K8M08_RS10150	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
K8M08_RS10155	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
K8M08_RS10170	COG0531	amino acid
K8M08_RS10175	COG0697	spore germination
K8M08_RS10180	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K8M08_RS10195	COG4990	cell redox homeostasis
K8M08_RS10200	COG0833	amino acid
K8M08_RS10205	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
K8M08_RS10210	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
K8M08_RS10225	COG0569	domain protein
K8M08_RS10225	COG0475	glutathione-regulated potassium exporter activity
K8M08_RS10235	COG2153	protein acetylation
K8M08_RS10250	COG2252	PERMEase
K8M08_RS10255	COG1113	amino acid transport
K8M08_RS10270	COG1114	Component of the transport system for branched-chain amino acids
K8M08_RS10275	COG3104	oligopeptide transport
K8M08_RS10290	COG1476	TRANSCRIPTIONal
K8M08_RS10295	COG3583	domain protein
K8M08_RS10295	COG3584	3D domain protein
K8M08_RS10300	COG0840	transmembrane signaling receptor activity
K8M08_RS10330	COG3568	Endonuclease Exonuclease Phosphatase
K8M08_RS10345	COG1063	alcohol dehydrogenase
K8M08_RS10365	COG1879	ABC-type sugar transport system periplasmic component
K8M08_RS10370	COG1172	Belongs to the binding-protein-dependent transport system permease family
K8M08_RS10385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K8M08_RS10390	COG1609	Transcriptional regulator
K8M08_RS10395	COG0477	Major facilitator Superfamily
K8M08_RS10400	COG1846	Transcriptional regulator
K8M08_RS10405	COG2271	Major facilitator Superfamily
K8M08_RS10415	COG4608	Belongs to the ABC transporter superfamily
K8M08_RS10420	COG0601	transmembrane transport
K8M08_RS10445	COG0659	secondary active sulfate transmembrane transporter activity
K8M08_RS10460	COG5002	protein histidine kinase activity
K8M08_RS10465	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
K8M08_RS10470	COG2378	regulation of single-species biofilm formation
K8M08_RS10480	COG1595	DNA-templated transcription, initiation
K8M08_RS10495	COG0833	amino acid
K8M08_RS10500	COG0765	amino acid transport
K8M08_RS10505	COG0765	amino acid transport
K8M08_RS10510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8M08_RS10515	COG1126	abc transporter atp-binding protein
K8M08_RS10520	COG1115	amino acid carrier protein
K8M08_RS10525	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
K8M08_RS10530	COG0697	spore germination
K8M08_RS10545	COG0366	Alpha amylase catalytic
K8M08_RS10550	COG1263	PTS System
K8M08_RS10550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8M08_RS10555	COG2188	Transcriptional regulator
K8M08_RS10560	COG0531	amino acid
K8M08_RS10580	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K8M08_RS10585	COG0714	Associated with various cellular activities
K8M08_RS10590	COG4548	von Willebrand factor, type A
K8M08_RS10600	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
K8M08_RS10605	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K8M08_RS10610	COG0156	8-amino-7-oxononanoate synthase activity
K8M08_RS10615	COG2226	methyltransferase
K8M08_RS10625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8M08_RS10630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8M08_RS10635	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8M08_RS10640	COG3104	oligopeptide transport
K8M08_RS10655	COG1620	l-lactate permease
K8M08_RS10660	COG1027	Aspartate ammonia-lyase
K8M08_RS10665	COG1253	flavin adenine dinucleotide binding
K8M08_RS10670	COG0346	lactoylglutathione lyase activity
K8M08_RS10675	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8M08_RS10680	COG1316	TRANSCRIPTIONal
K8M08_RS10685	COG2720	vancomycin resistance protein
K8M08_RS10705	COG3227	Zinc metalloprotease (Elastase)
K8M08_RS10720	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
K8M08_RS10725	COG2217	Heavy metal translocating P-type atpase
K8M08_RS10730	COG0640	Transcriptional regulator
K8M08_RS10735	COG0531	amino acid
K8M08_RS10750	COG2427	Protein of unknown function (DUF1641)
K8M08_RS10755	COG3383	formate dehydrogenase (NAD+) activity
K8M08_RS10760	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
K8M08_RS10765	COG0456	acetyltransferase
K8M08_RS10765	COG0454	-acetyltransferase
K8M08_RS10770	COG0745	RESPONSE REGULATOR receiver
K8M08_RS10775	COG5002	protein histidine kinase activity
K8M08_RS10785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8M08_RS10790	COG0697	spore germination
K8M08_RS10800	COG0281	malic enzyme
K8M08_RS10805	COG3493	citrate carrier protein
K8M08_RS10810	COG4565	transcriptional regulatory protein
K8M08_RS10815	COG3290	protein histidine kinase activity
K8M08_RS10825	COG4990	cell redox homeostasis
K8M08_RS10835	COG5002	protein histidine kinase activity
K8M08_RS10840	COG0745	RESPONSE REGULATOR receiver
K8M08_RS10865	COG2851	Citrate transporter
K8M08_RS10870	COG4565	transcriptional regulatory protein
K8M08_RS10875	COG3290	protein histidine kinase activity
K8M08_RS10885	COG2268	Band 7 protein
K8M08_RS10890	COG1585	Membrane protein implicated in regulation of membrane protease activity
K8M08_RS10900	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K8M08_RS10920	COG2766	serine protein kinase
K8M08_RS10930	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
K8M08_RS10940	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
K8M08_RS10955	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
K8M08_RS10960	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
K8M08_RS11075	COG0735	belongs to the Fur family
K8M08_RS11080	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
K8M08_RS11100	COG4555	ABC transporter
K8M08_RS11110	COG0070	glutamate synthase
K8M08_RS11110	COG0069	glutamate synthase activity
K8M08_RS11110	COG0067	glutamate synthase
K8M08_RS11115	COG4129	membrane
K8M08_RS11120	COG1132	(ABC) transporter
K8M08_RS11145	COG1194	a g-specific adenine glycosylase
K8M08_RS11150	COG1988	membrane-bound metal-dependent
K8M08_RS11180	COG1090	epimerase
K8M08_RS11185	COG0402	S-adenosylhomocysteine deaminase activity
K8M08_RS11205	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
K8M08_RS11220	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
K8M08_RS11220	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K8M08_RS11230	COG0463	Glycosyl transferase, family 2
K8M08_RS11250	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K8M08_RS11255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8M08_RS11255	COG1263	PTS System
K8M08_RS11285	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K8M08_RS11290	COG0833	amino acid
K8M08_RS11300	COG3829	transcription factor binding
K8M08_RS11320	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
K8M08_RS11340	COG0535	radical SAM domain protein
K8M08_RS11350	COG0387	Pfam Sodium calcium exchanger
K8M08_RS11355	COG3871	stress protein (general stress protein 26)
K8M08_RS11370	COG0586	Pfam SNARE associated Golgi protein
K8M08_RS11380	COG0681	Belongs to the peptidase S26 family
K8M08_RS11390	COG0697	spore germination
K8M08_RS11395	COG2217	Heavy metal translocating P-type atpase
K8M08_RS11400	COG1295	ribonuclease BN
K8M08_RS11410	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
K8M08_RS11425	COG3853	Toxic anion resistance protein (TelA)
K8M08_RS11435	COG0861	Integral membrane protein TerC family
K8M08_RS11440	COG2310	stress, protein
K8M08_RS11445	COG2310	stress, protein
K8M08_RS11450	COG2310	stress, protein
K8M08_RS11480	COG2270	Major facilitator Superfamily
K8M08_RS11525	COG0488	(ABC) transporter
K8M08_RS11535	COG1116	anion transmembrane transporter activity
K8M08_RS11545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K8M08_RS11560	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
K8M08_RS11590	COG1263	PTS System
K8M08_RS11590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8M08_RS11590	COG2190	(PTS) system
K8M08_RS11595	COG0366	Alpha amylase catalytic
K8M08_RS11600	COG0277	FAD linked oxidase domain protein
K8M08_RS11610	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K8M08_RS11615	COG0549	Belongs to the carbamate kinase family
K8M08_RS11640	COG0840	transmembrane signaling receptor activity
K8M08_RS11650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8M08_RS11655	COG0765	amino acid transport
K8M08_RS11665	COG0723	plastoquinol--plastocyanin reductase activity
K8M08_RS11665	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K8M08_RS11670	COG2814	Major facilitator Superfamily
K8M08_RS11675	COG3541	Predicted nucleotidyltransferase
K8M08_RS11720	COG0166	Belongs to the GPI family
K8M08_RS11735	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8M08_RS11740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8M08_RS11745	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8M08_RS11755	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
K8M08_RS11765	COG0450	alkyl hydroperoxide reductase
K8M08_RS11780	COG1473	amidohydrolase
K8M08_RS11785	COG1757	Na H antiporter
K8M08_RS11810	COG4807	Protein conserved in bacteria
K8M08_RS11815	COG5002	protein histidine kinase activity
K8M08_RS11820	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K8M08_RS11825	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
K8M08_RS11830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8M08_RS11845	COG2309	aminopeptidase activity
K8M08_RS11850	COG2076	Multidrug Resistance protein
K8M08_RS11855	COG1012	belongs to the aldehyde dehydrogenase family
K8M08_RS11865	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K8M08_RS11870	COG0546	phosphoglycolate phosphatase activity
K8M08_RS11875	COG1597	lipid kinase activity
K8M08_RS11895	COG4682	membrane
K8M08_RS11900	COG1846	Transcriptional regulator
K8M08_RS11905	COG0003	Pfam Anion-transporting ATPase
K8M08_RS11920	COG1464	Belongs to the NlpA lipoprotein family
K8M08_RS11925	COG2011	ABC-type metal ion transport system permease component
K8M08_RS11935	COG1335	isochorismatase
K8M08_RS11955	COG4851	CamS sex pheromone cAM373 precursor
K8M08_RS11965	COG0210	DNA helicase
K8M08_RS11990	COG0151	Belongs to the GarS family
K8M08_RS12000	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
K8M08_RS12010	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
K8M08_RS12025	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
K8M08_RS12035	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
K8M08_RS12040	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
K8M08_RS12045	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
K8M08_RS12070	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
K8M08_RS12095	COG5002	protein histidine kinase activity
K8M08_RS12105	COG2252	PERMEase
K8M08_RS12115	COG0459	protein refolding
K8M08_RS12125	COG1266	CAAX protease self-immunity
K8M08_RS12140	COG0488	(ABC) transporter
K8M08_RS12150	COG0456	acetyltransferase
K8M08_RS12155	COG1214	PFAM Peptidase M22, glycoprotease
K8M08_RS12160	COG0802	atpase or kinase
K8M08_RS12255	COG2183	response to ionizing radiation
K8M08_RS12260	COG2337	Toxic component of a toxin-antitoxin (TA) module
K8M08_RS12265	COG0864	Transcriptional regulator
K8M08_RS12270	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K8M08_RS12275	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
K8M08_RS12285	COG0705	Rhomboid family
K8M08_RS12290	COG4294	response to UV
K8M08_RS12300	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
K8M08_RS12310	COG2814	Major facilitator Superfamily
K8M08_RS12315	COG0531	amino acid
K8M08_RS12325	COG0179	Fumarylacetoacetate (FAA) hydrolase
K8M08_RS12330	COG3185	4-Hydroxyphenylpyruvate dioxygenase
K8M08_RS12360	COG0561	phosphatase activity
K8M08_RS12365	COG4608	Belongs to the ABC transporter superfamily
K8M08_RS12370	COG0444	Belongs to the ABC transporter superfamily
K8M08_RS12375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K8M08_RS12380	COG0601	transmembrane transport
K8M08_RS12385	COG0747	negative chemotaxis
K8M08_RS12390	COG0747	negative chemotaxis
K8M08_RS12400	COG0842	Transport permease protein
K8M08_RS12405	COG0842	Transport permease protein
K8M08_RS12405	COG1511	domain protein
K8M08_RS12410	COG1131	(ABC) transporter
K8M08_RS12415	COG2197	response regulator
K8M08_RS12420	COG4585	Histidine kinase
K8M08_RS12425	COG0488	(ABC) transporter
K8M08_RS12450	COG5298	Protein conserved in bacteria
K8M08_RS12460	COG0084	hydrolase, TatD family'
K8M08_RS12470	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8M08_RS12480	COG1609	Transcriptional regulator
K8M08_RS12490	COG0204	Acyl-transferase
K8M08_RS12505	COG0697	spore germination
K8M08_RS12520	COG1910	domain protein
K8M08_RS12525	COG0725	ABC transporter, periplasmic molybdate-binding protein
K8M08_RS12530	COG4149	molybdate abc transporter
K8M08_RS12545	COG0656	L-ascorbic acid biosynthetic process
K8M08_RS12550	COG4166	transmembrane transport
K8M08_RS12555	COG4166	transmembrane transport
K8M08_RS12570	COG4166	transmembrane transport
K8M08_RS12575	COG4608	Belongs to the ABC transporter superfamily
K8M08_RS12580	COG0444	Belongs to the ABC transporter superfamily
K8M08_RS12585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K8M08_RS12590	COG0601	transmembrane transport
K8M08_RS12610	COG2814	Major facilitator Superfamily
K8M08_RS12620	COG2271	Major facilitator Superfamily
K8M08_RS12625	COG0277	FAD linked oxidase domain protein
K8M08_RS12640	COG1464	Belongs to the NlpA lipoprotein family
K8M08_RS12645	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
K8M08_RS12650	COG2011	ABC-type metal ion transport system permease component
K8M08_RS12655	COG1028	Short-chain dehydrogenase reductase Sdr
K8M08_RS12680	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
K8M08_RS12700	COG0596	Alpha beta hydrolase
K8M08_RS12705	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
K8M08_RS12720	COG4856	YbbR-like protein
K8M08_RS12725	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
K8M08_RS12805	COG0726	polysaccharide deacetylase
K8M08_RS12810	COG2194	sulfuric ester hydrolase activity
K8M08_RS12820	COG0489	protein tyrosine kinase activity
K8M08_RS12825	COG0860	N-Acetylmuramoyl-L-alanine amidase
K8M08_RS12850	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
K8M08_RS12885	COG0257	Belongs to the bacterial ribosomal protein bL36 family
K8M08_RS12895	COG0024	Methionine aminopeptidase
K8M08_RS12905	COG0201	protein transport
K8M08_RS12965	COG0255	Belongs to the universal ribosomal protein uL29 family
K8M08_RS13035	COG1358	cellular component organization or biogenesis
K8M08_RS13050	COG2813	Specifically methylates the guanine in position
K8M08_RS13070	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
K8M08_RS13075	COG0250	Participates in transcription elongation, termination and antitermination
K8M08_RS13080	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
K8M08_RS13095	COG3688	RNA-binding protein containing a PIN domain
K8M08_RS13100	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K8M08_RS13115	COG1045	serine acetyltransferase
K8M08_RS13125	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
K8M08_RS13135	COG4956	integral membrane protein (PIN domain superfamily)
K8M08_RS13145	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
K8M08_RS13150	COG0542	response to heat
K8M08_RS13160	COG3880	PFAM UvrB UvrC protein
K8M08_RS13250	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K8M08_RS13255	COG1396	sequence-specific DNA binding
K8M08_RS13260	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
K8M08_RS13265	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
K8M08_RS13270	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
K8M08_RS13275	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K8M08_RS13280	COG0512	Glutamine amidotransferase of anthranilate synthase
K8M08_RS13285	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
K8M08_RS13290	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K8M08_RS13305	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
K8M08_RS13310	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
K8M08_RS13320	COG2208	phosphoserine phosphatase activity
K8M08_RS13335	COG1098	S1 RNA binding domain
K8M08_RS13355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
K8M08_RS13360	COG3956	TIGRFAM MazG family protein
K8M08_RS13365	COG2244	polysaccharide biosynthetic process
K8M08_RS13370	COG2002	toxin-antitoxin pair type II binding
K8M08_RS13375	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
K8M08_RS13405	COG0251	oxidation-reduction process
K8M08_RS13410	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
K8M08_RS13425	COG4466	Protein conserved in bacteria
K8M08_RS13440	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
K8M08_RS13445	COG0084	hydrolase, TatD family'
K8M08_RS13455	COG2002	toxin-antitoxin pair type II binding
K8M08_RS13460	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
K8M08_RS13470	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
K8M08_RS13480	COG1774	PSP1 C-terminal conserved region
K8M08_RS13495	COG1982	Orn Lys Arg decarboxylase major
K8M08_RS13550	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
K8M08_RS13560	COG0590	tRNA wobble adenosine to inosine editing
K8M08_RS13565	COG1335	isochorismatase
K8M08_RS13570	COG1428	Deoxynucleoside kinase
K8M08_RS13575	COG1428	Deoxynucleoside kinase
K8M08_RS13605	COG1686	Belongs to the peptidase S11 family
K8M08_RS13610	COG0516	GMP reductase activity
K8M08_RS13610	COG0517	IMP dehydrogenase activity
K8M08_RS13645	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K8M08_RS13650	COG0187	DNA topoisomerase II activity
K8M08_RS13660	COG2501	S4 domain
K8M08_RS13665	COG0592	DNA-directed DNA polymerase activity
K8M08_RS13675	COG0230	Belongs to the bacterial ribosomal protein bL34 family
K8M08_RS13685	COG0706	membrane insertase activity
K8M08_RS13690	COG1847	R3H domain protein
K8M08_RS13715	COG1192	Involved in chromosome partitioning
K8M08_RS13720	COG1475	DNA binding
K8M08_RS13730	COG0668	transmembrane transport
K8M08_RS13735	COG4481	Protein conserved in bacteria
K8M08_RS13740	COG0012	GTP binding
K8M08_RS13750	COG0629	single-stranded DNA binding
K8M08_RS13760	COG4241	membrane
K8M08_RS13765	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
K8M08_RS13775	COG0305	Participates in initiation and elongation during chromosome replication
K8M08_RS13805	COG0745	RESPONSE REGULATOR receiver
K8M08_RS13810	COG5002	protein histidine kinase activity
K8M08_RS13815	COG4863	YycH protein
K8M08_RS13820	COG4853	Protein conserved in bacteria
K8M08_RS13825	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
K8M08_RS13830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K8M08_RS13850	COG1164	Oligoendopeptidase f
K8M08_RS13875	COG1272	protein, Hemolysin III
K8M08_RS13880	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
K8M08_RS13900	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
K8M08_RS13905	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
K8M08_RS13910	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K8M08_RS13915	COG2814	Major facilitator Superfamily
K8M08_RS13920	COG3275	phosphorelay sensor kinase activity
K8M08_RS13925	COG3279	Response regulator of the LytR AlgR family
K8M08_RS13940	COG0628	permease
K8M08_RS13945	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K8M08_RS13945	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K8M08_RS13950	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K8M08_RS13955	COG1309	transcriptional regulator
K8M08_RS13960	COG0463	Glycosyl transferase, family 2
K8M08_RS13980	COG0488	(ABC) transporter
K8M08_RS13995	COG1607	acyl-coa hydrolase
K8M08_RS14005	COG0840	transmembrane signaling receptor activity
K8M08_RS14030	COG0477	Major facilitator Superfamily
K8M08_RS14035	COG3279	Response regulator of the LytR AlgR family
K8M08_RS14040	COG1966	Carbon starvation protein
K8M08_RS14045	COG2879	small protein
K8M08_RS14050	COG3706	GGDEF domain
K8M08_RS14055	COG0351	phosphomethylpyrimidine kinase
K8M08_RS14060	COG4585	Histidine kinase
K8M08_RS14060	COG2203	Gaf domain
K8M08_RS14065	COG2197	response regulator
K8M08_RS14075	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K8M08_RS14080	COG1011	Hydrolase
K8M08_RS14090	COG2873	o-acetylhomoserine
K8M08_RS14100	COG0460	homoserine dehydrogenase
K8M08_RS14110	COG1609	Transcriptional regulator
K8M08_RS14115	COG2755	lipolytic protein G-D-S-L family
K8M08_RS14120	COG1131	(ABC) transporter
K8M08_RS14125	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
K8M08_RS14135	COG2814	Major facilitator Superfamily
K8M08_RS14140	COG0561	phosphatase activity
K8M08_RS14145	COG2233	PERMEase
K8M08_RS14150	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
K8M08_RS14160	COG2363	Small membrane protein
K8M08_RS14170	COG3773	Cell wall hydrolase
K8M08_RS14185	COG0280	phosphate acetyltransferase
K8M08_RS14210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8M08_RS14215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8M08_RS14220	COG1120	ATPase activity
K8M08_RS14225	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8M08_RS14230	COG1078	dGTPase activity
K8M08_RS14240	COG1994	Peptidase M50
K8M08_RS14250	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8M08_RS14255	COG0584	glycerophosphoryl diester phosphodiesterase
K8M08_RS14260	COG0789	Transcriptional regulator
K8M08_RS14265	COG2814	Major facilitator Superfamily
K8M08_RS14290	COG1619	proteins homologs of microcin C7 resistance protein MccF
K8M08_RS14295	COG4506	Protein conserved in bacteria
K8M08_RS14305	COG1595	DNA-templated transcription, initiation
K8M08_RS14330	COG2234	aminopeptidase activity
K8M08_RS14335	COG0024	Methionine aminopeptidase
K8M08_RS14340	COG1131	(ABC) transporter
K8M08_RS14345	COG0842	Transport permease protein
K8M08_RS14350	COG4585	Histidine kinase
K8M08_RS14355	COG2197	response regulator
K8M08_RS14375	COG5001	Diguanylate cyclase
K8M08_RS14375	COG3300	MHYT domain
K8M08_RS14385	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K8M08_RS14390	COG0247	lactate metabolic process
K8M08_RS14390	COG2181	nitrate reductase activity
K8M08_RS14395	COG0183	Belongs to the thiolase family
K8M08_RS14400	COG1250	3-hydroxyacyl-CoA dehydrogenase
K8M08_RS14405	COG1960	acyl-CoA dehydrogenase activity
K8M08_RS14410	COG1960	acyl-CoA dehydrogenase activity
K8M08_RS14430	COG4821	SIS domain
K8M08_RS14450	COG1494	fructose-1,6-bisphosphatase
K8M08_RS14455	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
K8M08_RS14475	COG2890	protein-(glutamine-N5) methyltransferase activity
K8M08_RS14490	COG0009	L-threonylcarbamoyladenylate synthase
K8M08_RS14505	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K8M08_RS14510	COG2259	Doxx family
K8M08_RS14515	COG2190	(PTS) system
K8M08_RS14525	COG0698	ribose 5-phosphate isomerase
K8M08_RS14560	COG0356	it plays a direct role in the translocation of protons across the membrane
K8M08_RS14610	COG3300	MHYT domain
K8M08_RS14610	COG5001	Diguanylate cyclase
K8M08_RS14625	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K8M08_RS14645	COG0839	Belongs to the complex I subunit 6 family
K8M08_RS14655	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K8M08_RS14660	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K8M08_RS14665	COG1007	ATP synthesis coupled electron transport
K8M08_RS14670	COG4836	Membrane
K8M08_RS14685	COG2385	sporulation resulting in formation of a cellular spore
K8M08_RS14690	COG3279	Response regulator of the LytR AlgR family
K8M08_RS14705	COG0739	heme binding
K8M08_RS14715	COG1609	Transcriptional regulator
K8M08_RS14725	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
K8M08_RS14730	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
K8M08_RS14735	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
K8M08_RS14750	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
K8M08_RS14755	COG1682	transport, permease protein
K8M08_RS14760	COG1134	teichoic acid transport
K8M08_RS14765	COG1210	Utp--glucose-1-phosphate uridylyltransferase
K8M08_RS14790	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
K8M08_RS14795	COG0745	RESPONSE REGULATOR receiver
K8M08_RS14800	COG5002	protein histidine kinase activity
K8M08_RS14825	COG1136	(ABC) transporter
K8M08_RS14830	COG0577	efflux transmembrane transporter activity
K8M08_RS14870	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K8M08_RS14875	COG4715	Zinc finger, swim domain protein
K8M08_RS14900	COG1388	LysM domain
K8M08_RS14900	COG3584	3D domain protein
K8M08_RS14905	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K8M08_RS14910	COG1215	transferase activity, transferring glycosyl groups
K8M08_RS14920	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8M08_RS14925	COG0791	NLP P60 protein
K8M08_RS14925	COG1388	LysM domain
K8M08_RS14935	COG1368	sulfuric ester hydrolase activity
K8M08_RS14945	COG2389	metal-binding protein
K8M08_RS14955	COG1620	l-lactate permease
K8M08_RS14965	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
K8M08_RS14970	COG1294	oxidase, subunit
K8M08_RS14975	COG1271	oxidase subunit
K8M08_RS14985	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
K8M08_RS14990	COG0583	DNA-binding transcription factor activity
K8M08_RS14995	COG1511	domain protein
K8M08_RS15000	COG0346	lactoylglutathione lyase activity
K8M08_RS15010	COG1301	dicarboxylic acid transport
K8M08_RS15015	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K8M08_RS15025	COG1447	Phosphotransferase system cellobiose-specific component IIA
K8M08_RS15045	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K8M08_RS15050	COG1447	Phosphotransferase system cellobiose-specific component IIA
K8M08_RS15055	COG1486	melibiose metabolic process
K8M08_RS15075	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
K8M08_RS15075	COG3933	PFAM sigma-54 factor interaction domain-containing protein
K8M08_RS15085	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
K8M08_RS15090	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
K8M08_RS15095	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
K8M08_RS15100	COG1316	TRANSCRIPTIONal
K8M08_RS15105	COG1739	Uncharacterized protein family UPF0029
K8M08_RS15110	COG1307	EDD domain protein, DegV family
K8M08_RS15115	COG1733	regulation of RNA biosynthetic process
K8M08_RS15120	COG1388	LysM domain
K8M08_RS15120	COG0791	NLP P60 protein
K8M08_RS15125	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
K8M08_RS15130	COG1040	competence protein
K8M08_RS15135	COG1278	Cold shock
K8M08_RS15140	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
K8M08_RS15160	COG2884	Cell division ATP-binding protein ftsE
K8M08_RS15165	COG2177	Part of the ABC transporter FtsEX involved in
K8M08_RS15170	COG0793	Belongs to the peptidase S41A family
K8M08_RS15170	COG3409	Peptidoglycan-binding domain 1 protein
K8M08_RS15175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K8M08_RS15180	COG1132	(ABC) transporter
K8M08_RS15190	COG0488	(ABC) transporter
K8M08_RS15195	COG0655	NAD(P)H dehydrogenase (quinone) activity
K8M08_RS15205	COG0583	DNA-binding transcription factor activity
K8M08_RS15225	COG0789	Transcriptional regulator
K8M08_RS15240	COG0556	nucleotide-excision repair
K8M08_RS15245	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
K8M08_RS15255	COG1950	PFAM Membrane protein of
K8M08_RS15275	COG0110	maltose O-acetyltransferase activity
K8M08_RS15280	COG0457	Tetratricopeptide repeat
K8M08_RS15285	COG0492	ferredoxin-NADP+ reductase activity
K8M08_RS15295	COG1051	belongs to the nudix hydrolase family
K8M08_RS15305	COG0391	Required for morphogenesis under gluconeogenic growth conditions
K8M08_RS15315	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
K8M08_RS15325	COG2323	membrane
K8M08_RS15340	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K8M08_RS15365	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
K8M08_RS15380	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
K8M08_RS15415	COG1346	cytolysis
K8M08_RS15420	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
K8M08_RS15425	COG1647	Serine aminopeptidase, S33
K8M08_RS15430	COG0557	exoribonuclease II activity
K8M08_RS15475	COG1136	(ABC) transporter
K8M08_RS15495	COG1136	(ABC) transporter
K8M08_RS15500	COG0745	RESPONSE REGULATOR receiver
K8M08_RS15505	COG5002	protein histidine kinase activity
K8M08_RS15570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8M08_RS15590	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
K8M08_RS15600	COG3290	protein histidine kinase activity
K8M08_RS15600	COG0840	transmembrane signaling receptor activity
K8M08_RS15615	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
K8M08_RS15620	COG1252	NADH dehydrogenase
K8M08_RS15630	COG1733	regulation of RNA biosynthetic process
K8M08_RS15635	COG2814	Major facilitator Superfamily
K8M08_RS15640	COG0656	L-ascorbic acid biosynthetic process
K8M08_RS15655	COG2910	NAD(P)H-binding
K8M08_RS15660	COG1115	amino acid carrier protein
K8M08_RS15665	COG1115	amino acid carrier protein
K8M08_RS15670	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8M08_RS15675	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8M08_RS15695	COG1611	Belongs to the LOG family
K8M08_RS15710	COG0783	Belongs to the Dps family
K8M08_RS15715	COG1115	amino acid carrier protein
K8M08_RS15720	COG0490	domain, Protein
K8M08_RS15725	COG0475	glutathione-regulated potassium exporter activity
K8M08_RS15730	COG0586	Pfam SNARE associated Golgi protein
K8M08_RS15745	COG1741	Belongs to the pirin family
K8M08_RS15750	COG3227	Zinc metalloprotease (Elastase)
K8M08_RS15755	COG2151	metal-sulfur cluster biosynthetic enzyme
K8M08_RS15760	COG0840	transmembrane signaling receptor activity
K8M08_RS15785	COG5002	protein histidine kinase activity
K8M08_RS15790	COG0745	RESPONSE REGULATOR receiver
K8M08_RS15795	COG1376	ErfK ybiS ycfS ynhG family protein
K8M08_RS15805	COG0586	Pfam SNARE associated Golgi protein
K8M08_RS15840	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8M08_RS15865	COG0531	amino acid
K8M08_RS15870	COG2814	Major facilitator Superfamily
K8M08_RS15890	COG0840	transmembrane signaling receptor activity
K8M08_RS15895	COG0011	TIGRFAM Protein of
K8M08_RS15910	COG1686	Belongs to the peptidase S11 family
K8M08_RS15920	COG1024	Enoyl-CoA hydratase
K8M08_RS15920	COG1250	3-hydroxyacyl-CoA dehydrogenase
K8M08_RS15925	COG0183	Belongs to the thiolase family
K8M08_RS15930	COG1960	acyl-CoA dehydrogenase activity
K8M08_RS15935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8M08_RS15940	COG1309	transcriptional regulator
K8M08_RS16015	COG1393	Belongs to the ArsC family
K8M08_RS16030	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
K8M08_RS16035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8M08_RS16045	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
K8M08_RS16050	COG2011	ABC-type metal ion transport system permease component
K8M08_RS16055	COG1464	Belongs to the NlpA lipoprotein family
K8M08_RS16060	COG1464	Belongs to the NlpA lipoprotein family
K8M08_RS16065	COG0396	ATPase activity
K8M08_RS16070	COG0719	Fe-S assembly protein
K8M08_RS16075	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
K8M08_RS16080	COG0822	iron-sulfur transferase activity
K8M08_RS16085	COG0719	Fe-S assembly protein
K8M08_RS16095	COG1695	Transcriptional regulator
K8M08_RS16100	COG0737	Belongs to the 5'-nucleotidase family
K8M08_RS16105	COG3377	Domain of unknown function (DUF1805)
K8M08_RS16115	COG0739	heme binding
K8M08_RS16140	COG4377	Putative membrane peptidase family (DUF2324)
K8M08_RS16145	COG0789	Transcriptional regulator
K8M08_RS16155	COG4470	Protein conserved in bacteria
K8M08_RS16170	COG1494	fructose-1,6-bisphosphatase
K8M08_RS16175	COG2445	Protein of unknown function DUF86
K8M08_RS16185	COG0647	UMP catabolic process
K8M08_RS16190	COG2249	NAD(P)H dehydrogenase (quinone) activity
K8M08_RS16200	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
K8M08_RS16205	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
K8M08_RS16215	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
K8M08_RS16220	COG4837	Protein of unknown function (DUF1462)
K8M08_RS16240	COG2824	Alkylphosphonate utilization operon protein PhnA
K8M08_RS16245	COG0390	transport system, permease component
K8M08_RS16260	COG1252	NADH dehydrogenase
K8M08_RS16275	COG0316	Belongs to the HesB IscA family
K8M08_RS16300	COG1683	Conserved Protein
K8M08_RS16315	COG3708	Transcriptional regulator
K8M08_RS16325	COG1252	NADH dehydrogenase
K8M08_RS16340	COG3584	3D domain protein
K8M08_RS16355	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K8M08_RS16360	COG1210	Utp--glucose-1-phosphate uridylyltransferase
K8M08_RS16365	COG1268	BioY protein
K8M08_RS16375	COG2050	protein possibly involved in aromatic compounds catabolism
K8M08_RS16395	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
K8M08_RS16400	COG5018	Exonuclease
K8M08_RS16420	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
K8M08_RS16430	COG2267	carboxylic ester hydrolase activity
K8M08_RS16435	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K8M08_RS16440	COG1522	sequence-specific DNA binding
K8M08_RS16445	COG0436	Aminotransferase
K8M08_RS16450	COG1098	S1 RNA binding domain
K8M08_RS16455	COG2155	Conserved Protein
K8M08_RS16470	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
K8M08_RS16475	COG1285	pathogenesis
K8M08_RS16510	COG0544	peptidyl-prolyl cis-trans isomerase activity
K8M08_RS16605	COG1595	DNA-templated transcription, initiation
K8M08_RS16620	COG1404	Belongs to the peptidase S8 family
K8M08_RS16640	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
K8M08_RS16650	COG0058	SHG alpha-glucan phosphorylase activity
K8M08_RS16675	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
K8M08_RS16680	COG1575	Belongs to the MenA family. Type 1 subfamily
K8M08_RS16685	COG1169	isochorismate synthase
K8M08_RS16695	COG0596	Alpha beta hydrolase
K8M08_RS16700	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
K8M08_RS16710	COG4948	Mandelate Racemase Muconate Lactonizing
K8M08_RS16730	COG3964	amidohydrolase
K8M08_RS16750	COG2188	Transcriptional regulator
K8M08_RS16775	COG0577	efflux transmembrane transporter activity
K8M08_RS16780	COG1136	(ABC) transporter
K8M08_RS16785	COG0577	efflux transmembrane transporter activity
K8M08_RS16790	COG0577	efflux transmembrane transporter activity
K8M08_RS16795	COG2205	protein histidine kinase activity
K8M08_RS16800	COG0745	RESPONSE REGULATOR receiver
K8M08_RS16805	COG0640	Transcriptional regulator
K8M08_RS16810	COG5658	integral membrane protein
K8M08_RS16815	COG3708	Transcriptional regulator
K8M08_RS16815	COG2207	Transcriptional regulator
K8M08_RS16820	COG1136	(ABC) transporter
K8M08_RS16825	COG0577	efflux transmembrane transporter activity
K8M08_RS16835	COG4977	sequence-specific DNA binding
K8M08_RS16845	COG0586	Pfam SNARE associated Golgi protein
K8M08_RS16885	COG1597	lipid kinase activity
K8M08_RS16890	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
K8M08_RS16915	COG0745	RESPONSE REGULATOR receiver
K8M08_RS16920	COG5002	protein histidine kinase activity
K8M08_RS16965	COG1842	Phage shock protein A
K8M08_RS16990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8M08_RS17015	COG1294	oxidase, subunit
K8M08_RS17020	COG1271	oxidase subunit
K8M08_RS17025	COG0288	reversible hydration of carbon dioxide
K8M08_RS17055	COG0494	nUDIX hydrolase
K8M08_RS17080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K8M08_RS17085	COG1116	anion transmembrane transporter activity
K8M08_RS17090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K8M08_RS17105	COG1368	sulfuric ester hydrolase activity
K8M08_RS17110	COG2267	carboxylic ester hydrolase activity
K8M08_RS17115	COG4191	Histidine kinase
K8M08_RS17120	COG5002	protein histidine kinase activity
K8M08_RS17190	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8M08_RS17205	COG0521	Mo-molybdopterin cofactor biosynthetic process
K8M08_RS17215	COG0438	transferase activity, transferring glycosyl groups
K8M08_RS17220	COG0671	phosphoesterase, PA-phosphatase related
K8M08_RS17225	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
K8M08_RS17230	COG2267	carboxylic ester hydrolase activity
K8M08_RS17255	COG1794	racemase activity, acting on amino acids and derivatives
K8M08_RS17270	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
K8M08_RS17275	COG1242	4 iron, 4 sulfur cluster binding
K8M08_RS17295	COG1136	(ABC) transporter
K8M08_RS17305	COG0582	viral genome integration into host DNA
K8M08_RS17310	COG0490	domain, Protein
K8M08_RS17315	COG0475	glutathione-regulated potassium exporter activity
K8M08_RS17320	COG2814	Major facilitator Superfamily
K8M08_RS17360	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
K8M08_RS17370	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K8M08_RS17390	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K8M08_RS17395	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K8M08_RS17405	COG0303	'Molybdopterin
K8M08_RS17410	COG1763	Mo-molybdopterin cofactor biosynthetic process
K8M08_RS17415	COG0314	molybdopterin synthase activity
K8M08_RS17440	COG1329	Transcriptional regulator
K8M08_RS17460	COG3832	glyoxalase III activity
K8M08_RS17470	COG2814	Major facilitator Superfamily
K8M08_RS17475	COG2081	HI0933 family
K8M08_RS17480	COG2244	polysaccharide biosynthetic process
K8M08_RS17485	COG1187	pseudouridine synthase activity
K8M08_RS17490	COG1349	DNA-binding transcription factor activity
K8M08_RS17495	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K8M08_RS17505	COG1523	belongs to the glycosyl hydrolase 13 family
K8M08_RS17510	COG0510	thiamine kinase activity
K8M08_RS17525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8M08_RS17535	COG1363	Peptidase, m42
K8M08_RS17540	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
K8M08_RS17545	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8M08_RS17555	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K8M08_RS17570	COG1674	ftsk spoiiie
K8M08_RS17590	COG1695	Transcriptional regulator
K8M08_RS17595	COG0789	Transcriptional regulator
K8M08_RS17600	COG0697	spore germination
K8M08_RS17605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8M08_RS17620	COG2309	aminopeptidase activity
K8M08_RS17630	COG3118	belongs to the thioredoxin family
K8M08_RS17635	COG4851	CamS sex pheromone cAM373 precursor
K8M08_RS17640	COG1609	Transcriptional regulator
K8M08_RS17675	COG0666	response to abiotic stimulus
K8M08_RS17680	COG5002	protein histidine kinase activity
K8M08_RS17685	COG0745	RESPONSE REGULATOR receiver
K8M08_RS17695	COG2267	carboxylic ester hydrolase activity
K8M08_RS17700	COG0123	including yeast histone deacetylase and acetoin utilization protein
K8M08_RS17705	COG0517	IMP dehydrogenase activity
K8M08_RS17710	COG0454	-acetyltransferase
K8M08_RS17715	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K8M08_RS17730	COG1595	DNA-templated transcription, initiation
K8M08_RS17760	COG0626	cystathionine gamma-synthase activity
K8M08_RS17765	COG1956	GAF domain-containing protein
K8M08_RS17770	COG1309	transcriptional regulator
K8M08_RS17775	COG0697	spore germination
K8M08_RS17780	COG0583	DNA-binding transcription factor activity
K8M08_RS17790	COG1104	cysteine desulfurase activity
K8M08_RS17805	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K8M08_RS17815	COG1574	metal-dependent hydrolase with the TIM-barrel fold
K8M08_RS17830	COG3874	Sporulation protein YtfJ
K8M08_RS17835	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
K8M08_RS17840	COG0827	DNA restriction-modification system
K8M08_RS17865	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8M08_RS17900	COG0589	response to stress
K8M08_RS17905	COG1028	Short-chain dehydrogenase reductase Sdr
K8M08_RS17920	COG1476	TRANSCRIPTIONal
K8M08_RS17930	COG0662	Cupin 2, conserved barrel domain protein
K8M08_RS17935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8M08_RS17975	COG0006	proline dipeptidase activity
K8M08_RS17990	COG4109	DRTGG domain
K8M08_RS18000	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
K8M08_RS18015	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
K8M08_RS18030	COG0587	DNA-directed DNA polymerase activity
K8M08_RS18035	COG0281	malic enzyme
K8M08_RS18040	COG1725	Transcriptional regulator
K8M08_RS18065	COG3030	protein affecting phage T7 exclusion by the F plasmid
K8M08_RS18070	COG0628	permease
K8M08_RS18080	COG0372	Belongs to the citrate synthase family
K8M08_RS18085	COG0538	isocitrate dehydrogenase activity
K8M08_RS18105	COG0745	RESPONSE REGULATOR receiver
K8M08_RS18110	COG5002	protein histidine kinase activity
K8M08_RS18115	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K8M08_RS18115	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K8M08_RS18125	COG1971	Probably functions as a manganese efflux pump
K8M08_RS18130	COG0237	dephospho-CoA kinase activity
K8M08_RS18135	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
K8M08_RS18140	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
K8M08_RS18150	COG3611	Membrane attachment protein
K8M08_RS18155	COG1484	DNA-dependent DNA replication
K8M08_RS18165	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
K8M08_RS18190	COG1363	Peptidase, m42
K8M08_RS18195	COG1309	transcriptional regulator
K8M08_RS18200	COG1566	PFAM secretion protein HlyD family protein
K8M08_RS18205	COG2814	Major facilitator Superfamily
K8M08_RS18215	COG1418	mRNA catabolic process
K8M08_RS18225	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K8M08_RS18270	COG1286	toxin biosynthetic process
K8M08_RS18275	COG1796	DNA polymerase
K8M08_RS18275	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
K8M08_RS18285	COG1187	pseudouridine synthase activity
K8M08_RS18290	COG1114	Component of the transport system for branched-chain amino acids
K8M08_RS18295	COG5386	Cell surface protein
K8M08_RS18305	COG5386	Cell surface protein
K8M08_RS18320	COG1120	ATPase activity
K8M08_RS18325	COG4509	Sortase family
K8M08_RS18335	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
K8M08_RS18340	COG4895	conserved protein (DUF2196)
K8M08_RS18350	COG0745	RESPONSE REGULATOR receiver
K8M08_RS18355	COG2205	protein histidine kinase activity
K8M08_RS18360	COG1131	(ABC) transporter
K8M08_RS18390	COG2318	DinB family
K8M08_RS18405	COG0318	PFAM AMP-dependent synthetase and ligase
K8M08_RS18410	COG1309	transcriptional regulator
K8M08_RS18415	COG1024	Enoyl-CoA hydratase
K8M08_RS18420	COG2086	electron transfer activity
K8M08_RS18425	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
K8M08_RS18430	COG3118	belongs to the thioredoxin family
K8M08_RS18440	COG1719	4-vinyl reductase, 4VR
K8M08_RS18445	COG2009	succinate dehydrogenase
K8M08_RS18450	COG1053	succinate dehydrogenase
K8M08_RS18455	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
K8M08_RS18460	COG0824	Thioesterase
K8M08_RS18465	COG1876	peptidase activity
K8M08_RS18470	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
K8M08_RS18475	COG1360	Flagellar Motor Protein
K8M08_RS18480	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
K8M08_RS18485	COG4152	abc transporter atp-binding protein
K8M08_RS18490	COG1668	transmembrane transport
K8M08_RS18495	COG1959	2 iron, 2 sulfur cluster binding
K8M08_RS18505	COG0697	spore germination
K8M08_RS18510	COG1396	sequence-specific DNA binding
K8M08_RS18515	COG1983	PspC domain protein
K8M08_RS18525	COG3279	Response regulator of the LytR AlgR family
K8M08_RS18530	COG3275	phosphorelay sensor kinase activity
K8M08_RS18535	COG4608	Belongs to the ABC transporter superfamily
K8M08_RS18540	COG0444	Belongs to the ABC transporter superfamily
K8M08_RS18550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K8M08_RS18560	COG0402	S-adenosylhomocysteine deaminase activity
K8M08_RS18565	COG0402	S-adenosylhomocysteine deaminase activity
K8M08_RS18575	COG2233	PERMEase
K8M08_RS18580	COG2197	response regulator
K8M08_RS18595	COG1309	transcriptional regulator
K8M08_RS18615	COG5401	PFAM Sporulation and spore germination
K8M08_RS18630	COG0622	Phosphoesterase
K8M08_RS18675	COG1067	ATP-dependent peptidase activity
K8M08_RS18675	COG0470	DNA polymerase III
K8M08_RS18690	COG1764	response to oxidative stress
K8M08_RS18695	COG1846	Transcriptional regulator
K8M08_RS18705	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K8M08_RS18715	COG1587	Uroporphyrinogen-III synthase
K8M08_RS18720	COG0113	porphobilinogen synthase activity
K8M08_RS18730	COG1388	LysM domain
K8M08_RS18745	COG0285	dihydrofolate synthase activity
K8M08_RS18765	COG1077	Cell shape determining protein MreB Mrl
K8M08_RS18785	COG2894	cell division
K8M08_RS18790	COG0739	heme binding
K8M08_RS18795	COG1994	Peptidase M50
K8M08_RS18800	COG1530	ribonuclease E activity
K8M08_RS18810	COG2868	ribosomal protein
K8M08_RS18820	COG3290	protein histidine kinase activity
K8M08_RS18830	COG0745	RESPONSE REGULATOR receiver
K8M08_RS18835	COG5002	protein histidine kinase activity
K8M08_RS18840	COG1136	(ABC) transporter
K8M08_RS18845	COG0577	efflux transmembrane transporter activity
K8M08_RS18850	COG0577	efflux transmembrane transporter activity
K8M08_RS18855	COG0077	Prephenate dehydratase
K8M08_RS18860	COG2258	MOSC domain
K8M08_RS18865	COG1827	regulation of RNA biosynthetic process
K8M08_RS18870	COG1104	cysteine desulfurase activity
K8M08_RS18875	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
K8M08_RS18880	COG0157	Belongs to the NadC ModD family
K8M08_RS18905	COG0640	Transcriptional regulator
K8M08_RS18910	COG0697	spore germination
K8M08_RS18920	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
K8M08_RS18950	COG1862	Preprotein translocase
K8M08_RS18960	COG2323	membrane
K8M08_RS18965	COG2244	polysaccharide biosynthetic process
K8M08_RS18975	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K8M08_RS18975	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K8M08_RS18980	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
K8M08_RS18985	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
K8M08_RS18985	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
K8M08_RS18995	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
K8M08_RS19020	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
K8M08_RS19030	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
K8M08_RS19035	COG1959	2 iron, 2 sulfur cluster binding
K8M08_RS19040	COG1104	cysteine desulfurase activity
K8M08_RS19055	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
K8M08_RS19075	COG0628	permease
K8M08_RS19105	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
K8M08_RS19110	COG4122	O-methyltransferase activity
K8M08_RS19115	COG0826	peptidase U32
K8M08_RS19120	COG0826	peptidase U32
K8M08_RS19135	COG0768	penicillin binding
K8M08_RS19160	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K8M08_RS19165	COG0626	cystathionine gamma-synthase activity
K8M08_RS19170	COG1454	alcohol dehydrogenase
K8M08_RS19170	COG1012	belongs to the aldehyde dehydrogenase family
K8M08_RS19180	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8M08_RS19220	COG2259	Doxx family
K8M08_RS19225	COG2514	catechol 2,3-dioxygenase activity
K8M08_RS19235	COG3186	Phenylalanine-4-hydroxylase
K8M08_RS19240	COG1404	Belongs to the peptidase S8 family
K8M08_RS19275	COG2267	carboxylic ester hydrolase activity
K8M08_RS19285	COG1785	Belongs to the alkaline phosphatase family
K8M08_RS19295	COG2357	RelA SpoT domain protein
K8M08_RS19300	COG0778	Nitroreductase
K8M08_RS19330	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
K8M08_RS19335	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
K8M08_RS19345	COG1534	Rna-binding protein
K8M08_RS19360	COG0799	negative regulation of ribosome biogenesis
K8M08_RS19365	COG2226	methyltransferase
K8M08_RS19370	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K8M08_RS19375	COG1555	photosystem II stabilization
K8M08_RS19375	COG1596	polysaccharide export
K8M08_RS19380	COG2131	deaminase
K8M08_RS19385	COG0658	competence protein
K8M08_RS19385	COG2333	competence protein COMEC
K8M08_RS19395	COG1466	dna polymerase III delta subunit
K8M08_RS19420	COG1733	regulation of RNA biosynthetic process
K8M08_RS19425	COG0635	Involved in the biosynthesis of porphyrin-containing compound
K8M08_RS19455	COG1385	rRNA (uridine-N3-)-methyltransferase activity
K8M08_RS19460	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
K8M08_RS19465	COG0828	Belongs to the bacterial ribosomal protein bS21 family
K8M08_RS19470	COG1610	YqeY-like protein
K8M08_RS19485	COG1702	phosphate starvation-inducible protein PhoH
K8M08_RS19490	COG1480	7TM receptor with intracellular HD hydrolase
K8M08_RS19500	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
K8M08_RS19505	COG0295	cytidine deaminase activity
K8M08_RS19510	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
K8M08_RS19525	COG0517	IMP dehydrogenase activity
K8M08_RS19535	COG0358	DNA primase activity
K8M08_RS19540	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
K8M08_RS19545	COG2010	Cytochrome c
K8M08_RS19550	COG2384	SAM-dependent methyltransferase
K8M08_RS19555	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
K8M08_RS19585	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8M08_RS19590	COG1121	(ABC) transporter
K8M08_RS19595	COG1108	ABC-type Mn2 Zn2 transport systems permease components
K8M08_RS19600	COG0735	belongs to the Fur family
K8M08_RS19630	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
K8M08_RS19635	COG0477	Major facilitator Superfamily
K8M08_RS19640	COG0768	penicillin binding
K8M08_RS19645	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
K8M08_RS19650	COG0573	inorganic phosphate transmembrane transporter activity
K8M08_RS19655	COG0581	inorganic phosphate transmembrane transporter activity
K8M08_RS19665	COG0704	Plays a role in the regulation of phosphate uptake
K8M08_RS19670	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K8M08_RS19675	COG0267	Belongs to the bacterial ribosomal protein bL33 family
K8M08_RS19680	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
K8M08_RS19685	COG4483	Protein conserved in bacteria
K8M08_RS19690	COG1940	carbohydrate kinase activity
K8M08_RS19700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8M08_RS19720	COG0626	cystathionine gamma-synthase activity
K8M08_RS19725	COG0626	cystathionine gamma-synthase activity
K8M08_RS19730	COG0646	methionine synthase
K8M08_RS19730	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
K8M08_RS19735	COG1410	methionine synthase
K8M08_RS19735	COG0646	methionine synthase
K8M08_RS19785	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
K8M08_RS19790	COG1459	type II secretion system
K8M08_RS19800	COG4970	Tfp pilus assembly protein FimT
K8M08_RS19865	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K8M08_RS19895	COG1725	Transcriptional regulator
K8M08_RS19935	COG2076	Multidrug Resistance protein
K8M08_RS19940	COG2076	Multidrug Resistance protein
K8M08_RS19950	COG1609	Transcriptional regulator
K8M08_RS19960	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K8M08_RS19965	COG0095	Lipoate-protein ligase
K8M08_RS20000	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
K8M08_RS20010	COG3872	metal-dependent enzyme
K8M08_RS20025	COG0006	proline dipeptidase activity
K8M08_RS20050	COG3854	ATPases associated with a variety of cellular activities
K8M08_RS20095	COG0511	ligase activity, forming carbon-carbon bonds
K8M08_RS20100	COG0439	Biotin carboxylase
K8M08_RS20105	COG1302	Protein conserved in bacteria
K8M08_RS20130	COG0142	geranyltranstransferase activity
K8M08_RS20140	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
K8M08_RS20150	COG0497	DNA recombination
K8M08_RS20155	COG0750	zinc metalloprotease
K8M08_RS20160	COG0745	RESPONSE REGULATOR receiver
K8M08_RS20170	COG3093	addiction module antidote protein HigA
K8M08_RS20175	COG0584	glycerophosphoryl diester phosphodiesterase
K8M08_RS20185	COG3290	protein histidine kinase activity
K8M08_RS20185	COG3829	transcription factor binding
K8M08_RS20190	COG0280	phosphate acetyltransferase
K8M08_RS20205	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K8M08_RS20210	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K8M08_RS20215	COG0022	dehydrogenase e1 component
K8M08_RS20220	COG0508	dehydrogenase complex catalyzes the overall conversion of
K8M08_RS20225	COG0772	Belongs to the SEDS family
K8M08_RS20230	COG2323	membrane
K8M08_RS20250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8M08_RS20255	COG0765	amino acid transport
K8M08_RS20260	COG1126	abc transporter atp-binding protein
K8M08_RS20265	COG4129	membrane
K8M08_RS20270	COG1376	ErfK ybiS ycfS ynhG family protein
K8M08_RS20285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8M08_RS20290	COG2195	Cleaves the N-terminal amino acid of tripeptides
K8M08_RS20315	COG1760	l-serine dehydratase
K8M08_RS20320	COG1760	l-serine dehydratase
K8M08_RS20325	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K8M08_RS20330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8M08_RS20335	COG0300	oxidoreductase activity
K8M08_RS20360	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
K8M08_RS20380	COG1522	sequence-specific DNA binding
K8M08_RS20390	COG0737	Belongs to the 5'-nucleotidase family
K8M08_RS20395	COG1757	Na H antiporter
K8M08_RS20405	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K8M08_RS20420	COG1073	alpha beta
K8M08_RS20420	COG2226	methyltransferase
K8M08_RS20425	COG4106	trans-aconitate 2-methyltransferase activity
K8M08_RS20450	COG0307	riboflavin synthase, alpha
K8M08_RS20455	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K8M08_RS20455	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K8M08_RS20470	COG1073	alpha beta
K8M08_RS20475	COG0456	acetyltransferase
K8M08_RS20480	COG1609	Transcriptional regulator
K8M08_RS20485	COG2056	Na+-H+ antiporter family
K8M08_RS20490	COG0596	Alpha beta hydrolase
K8M08_RS20500	COG4085	toxin activity
K8M08_RS20500	COG1525	nuclease
K8M08_RS20500	COG0737	Belongs to the 5'-nucleotidase family
K8M08_RS20510	COG0456	acetyltransferase
K8M08_RS20510	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
K8M08_RS20515	COG0656	L-ascorbic acid biosynthetic process
K8M08_RS20520	COG0667	Aldo Keto reductase
K8M08_RS20540	COG1300	Membrane
K8M08_RS20545	COG0735	belongs to the Fur family
K8M08_RS20555	COG4974	Belongs to the 'phage' integrase family
K8M08_RS20580	COG0598	Magnesium transport protein CorA
K8M08_RS20595	COG1846	Transcriptional regulator
K8M08_RS20615	COG1131	(ABC) transporter
K8M08_RS20620	COG1725	Transcriptional regulator
K8M08_RS20625	COG1686	Belongs to the peptidase S11 family
K8M08_RS20645	COG0733	neurotransmitter:sodium symporter activity
K8M08_RS20670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K8M08_RS20685	COG0697	spore germination
K8M08_RS20690	COG0561	phosphatase activity
K8M08_RS20695	COG4086	secreted protein
K8M08_RS20700	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
K8M08_RS20710	COG0456	acetyltransferase
K8M08_RS20715	COG1547	Domain of unknown function (DUF309)
K8M08_RS20740	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
K8M08_RS20750	COG2188	Transcriptional regulator
K8M08_RS20760	COG3711	transcriptional antiterminator
K8M08_RS20765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8M08_RS20765	COG2190	(PTS) system
K8M08_RS20765	COG1263	PTS System
K8M08_RS20790	COG0778	Nitroreductase
K8M08_RS20795	COG2199	diguanylate cyclase activity
K8M08_RS20805	COG2084	Dehydrogenase
K8M08_RS20840	COG0436	Aminotransferase
K8M08_RS20845	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K8M08_RS20865	COG1028	Short-chain dehydrogenase reductase Sdr
K8M08_RS20870	COG1695	Transcriptional regulator
K8M08_RS20905	COG0183	Belongs to the thiolase family
K8M08_RS20910	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
K8M08_RS20945	COG3842	ATPase activity
K8M08_RS20950	COG0366	Alpha amylase catalytic
K8M08_RS20960	COG2182	Extracellular solute-binding protein
K8M08_RS20965	COG1175	transmembrane transport
K8M08_RS20970	COG3833	ABC-type maltose transport systems, permease component
K8M08_RS20975	COG1609	Transcriptional regulator
K8M08_RS20980	COG0436	Aminotransferase
K8M08_RS20990	COG2205	protein histidine kinase activity
K8M08_RS21000	COG3209	COG3209 Rhs family protein
K8M08_RS21020	COG2814	Major facilitator Superfamily
K8M08_RS21055	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
K8M08_RS21065	COG1408	metallophosphoesterase
K8M08_RS21070	COG1028	Short-chain dehydrogenase reductase Sdr
K8M08_RS21075	COG2200	EAL domain
K8M08_RS21090	COG4703	Protein of unknown function (DUF1797)
K8M08_RS21100	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
K8M08_RS21110	COG0517	IMP dehydrogenase activity
K8M08_RS21115	COG0583	DNA-binding transcription factor activity
K8M08_RS21135	COG0569	domain protein
K8M08_RS21140	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
K8M08_RS21150	COG0561	phosphatase activity
K8M08_RS21155	COG0242	peptide deformylase activity
K8M08_RS21165	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K8M08_RS21170	COG0022	dehydrogenase e1 component
K8M08_RS21220	COG1982	Orn Lys Arg decarboxylase major
K8M08_RS21240	COG0483	inositol monophosphate 1-phosphatase activity
K8M08_RS21250	COG1217	gtp-binding protein TYPA
K8M08_RS21265	COG4896	Protein conserved in bacteria
K8M08_RS21275	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
K8M08_RS21280	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
K8M08_RS21290	COG0772	Belongs to the SEDS family
K8M08_RS21295	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
K8M08_RS21330	COG3336	cytochrome c oxidase
K8M08_RS21340	COG2340	Cysteine-rich secretory protein family
K8M08_RS21355	COG0406	alpha-ribazole phosphatase activity
K8M08_RS21360	COG3679	Belongs to the UPF0342 family
K8M08_RS21375	COG0742	ribosomal rna small subunit methyltransferase
K8M08_RS21385	COG3314	Sporulation integral membrane protein YlbJ
K8M08_RS21390	COG1752	Esterase of the alpha-beta hydrolase superfamily
K8M08_RS21395	COG3480	Lon protease (S16) C-terminal proteolytic domain
K8M08_RS21405	COG1399	metal-binding, possibly nucleic acid-binding protein
K8M08_RS21410	COG0333	Belongs to the bacterial ribosomal protein bL32 family
K8M08_RS21425	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
K8M08_RS21440	COG4839	cell division protein FtsL
K8M08_RS21445	COG0768	penicillin binding
K8M08_RS21450	COG0768	penicillin binding
K8M08_RS21455	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
K8M08_RS21470	COG0772	Belongs to the SEDS family
K8M08_RS21485	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
K8M08_RS21490	COG0849	cell division
K8M08_RS21495	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
K8M08_RS21505	COG1191	sigma factor activity
K8M08_RS21510	COG1191	sigma factor activity
K8M08_RS21515	COG1873	PFAM PRC-barrel domain
K8M08_RS21525	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
K8M08_RS21535	COG0762	integral membrane protein
K8M08_RS21540	COG2302	S4 RNA-binding domain
K8M08_RS21545	COG3599	regulation of cell shape
K8M08_RS21565	COG0564	pseudouridine synthase activity
K8M08_RS21630	COG3069	C4-dicarboxylate transmembrane transporter activity
K8M08_RS21645	COG0006	proline dipeptidase activity
K8M08_RS21660	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
K8M08_RS21665	COG1561	YicC-like family, N-terminal region
K8M08_RS21685	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
K8M08_RS21690	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
K8M08_RS21695	COG0242	peptide deformylase activity
K8M08_RS21705	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
K8M08_RS21705	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
K8M08_RS21715	COG0631	protein serine/threonine phosphatase activity
K8M08_RS21720	COG0515	serine threonine protein kinase
K8M08_RS21720	COG2815	serine threonine protein kinase
K8M08_RS21730	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
K8M08_RS21735	COG1564	THIamine pyrophosphokinase
K8M08_RS21750	COG1302	Protein conserved in bacteria
K8M08_RS21755	COG1461	Dihydroxyacetone kinase
K8M08_RS21760	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
K8M08_RS21775	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
K8M08_RS21780	COG1028	Short-chain dehydrogenase reductase Sdr
K8M08_RS21785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K8M08_RS21795	COG1196	nuclear chromosome segregation
K8M08_RS21800	COG0552	protein localization to endoplasmic reticulum
K8M08_RS21810	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
K8M08_RS21820	COG1837	Belongs to the UPF0109 family
K8M08_RS21860	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
K8M08_RS21865	COG0758	DNA mediated transformation
K8M08_RS21870	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K8M08_RS21880	COG4974	Belongs to the 'phage' integrase family
K8M08_RS21910	COG0528	UMP kinase activity
K8M08_RS21925	COG4589	Belongs to the CDS family
K8M08_RS21935	COG0750	zinc metalloprotease
K8M08_RS21955	COG0195	Participates in both transcription termination and antitermination
K8M08_RS21960	COG2740	Nucleic-acid-binding protein implicated in transcription termination
K8M08_RS21965	COG1358	cellular component organization or biogenesis
K8M08_RS21975	COG1550	Protein conserved in bacteria
K8M08_RS21990	COG0196	riboflavin kinase activity
K8M08_RS22005	COG0726	polysaccharide deacetylase
K8M08_RS22010	COG0612	Peptidase, M16
K8M08_RS22015	COG1873	PFAM PRC-barrel domain
K8M08_RS22020	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K8M08_RS22025	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
K8M08_RS22030	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
K8M08_RS22035	COG0527	aspartate kinase activity
K8M08_RS22045	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
K8M08_RS22050	COG0740	serine-type endopeptidase activity
K8M08_RS22060	COG1674	ftsk spoiiie
K8M08_RS22065	COG2188	Transcriptional regulator
K8M08_RS22070	COG1744	ABC transporter substrate-binding protein PnrA-like
K8M08_RS22075	COG3845	ABC transporter
K8M08_RS22080	COG4603	Belongs to the binding-protein-dependent transport system permease family
K8M08_RS22085	COG1079	Belongs to the binding-protein-dependent transport system permease family
K8M08_RS22090	COG0612	Peptidase, M16
K8M08_RS22095	COG0612	Peptidase, M16
K8M08_RS22100	COG0300	oxidoreductase activity
K8M08_RS22115	COG1426	Protein conserved in bacteria
K8M08_RS22120	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
K8M08_RS22145	COG1692	metallophosphoesterase
K8M08_RS22150	COG2359	stage V sporulation protein S
K8M08_RS22160	COG0674	pyruvate-flavodoxin oxidoreductase activity
K8M08_RS22160	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
K8M08_RS22165	COG1013	pyruvate-flavodoxin oxidoreductase activity
K8M08_RS22175	COG4550	Control of competence regulator ComK, YlbF/YmcA
K8M08_RS22195	COG1131	(ABC) transporter
K8M08_RS22220	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
K8M08_RS22230	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
K8M08_RS22235	COG1368	sulfuric ester hydrolase activity
K8M08_RS22245	COG3773	Cell wall hydrolase
K8M08_RS22250	COG1404	Belongs to the peptidase S8 family
K8M08_RS22270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8M08_RS22275	COG1380	Effector of murein hydrolase LrgA
K8M08_RS22280	COG1346	cytolysis
K8M08_RS22290	COG0384	phenazine biosynthesis protein PhzF
K8M08_RS22325	COG5001	Diguanylate cyclase
K8M08_RS22325	COG3300	MHYT domain
K8M08_RS22345	COG2364	Membrane
K8M08_RS22355	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
K8M08_RS22360	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
K8M08_RS22365	COG2169	Transcriptional regulator
K8M08_RS22370	COG0708	Exodeoxyribonuclease III
K8M08_RS22375	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8M08_RS22380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8M08_RS22385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8M08_RS22390	COG1120	ATPase activity
K8M08_RS22395	COG2819	hydrolase of the alpha beta superfamily
K8M08_RS22405	COG1937	Protein conserved in bacteria
K8M08_RS22410	COG2608	mercury ion transmembrane transporter activity
K8M08_RS22415	COG2217	Heavy metal translocating P-type atpase
K8M08_RS22430	COG2116	formate transmembrane transporter activity
K8M08_RS22435	COG1408	metallophosphoesterase
K8M08_RS22445	COG1113	amino acid transport
K8M08_RS22455	COG2322	membrane
K8M08_RS22460	COG1979	alcohol dehydrogenase
K8M08_RS22465	COG1349	DNA-binding transcription factor activity
K8M08_RS22470	COG1105	Belongs to the carbohydrate kinase PfkB family
K8M08_RS22475	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K8M08_RS22475	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K8M08_RS22475	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
K8M08_RS22480	COG1388	LysM domain
K8M08_RS22480	COG3584	3D domain protein
K8M08_RS22510	COG0464	growth
K8M08_RS22515	COG2860	membrane
K8M08_RS22520	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
K8M08_RS22525	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
K8M08_RS22530	COG0789	Transcriptional regulator
K8M08_RS22535	COG0174	glutamine synthetase
K8M08_RS22545	COG2815	serine threonine protein kinase
K8M08_RS22545	COG0515	serine threonine protein kinase
K8M08_RS22560	COG1396	sequence-specific DNA binding
K8M08_RS22590	COG1484	DNA-dependent DNA replication
K8M08_RS22660	COG0582	viral genome integration into host DNA
K8M08_RS22780	COG4824	toxin secretion phage lysis holin
K8M08_RS22840	COG1695	Transcriptional regulator
K8M08_RS22860	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K8M08_RS22870	COG0737	Belongs to the 5'-nucleotidase family
K8M08_RS22875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8M08_RS22885	COG3639	organic phosphonate transmembrane transporter activity
K8M08_RS22910	COG1132	(ABC) transporter
K8M08_RS22915	COG1132	(ABC) transporter
K8M08_RS22930	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8M08_RS22930	COG3409	Peptidoglycan-binding domain 1 protein
K8M08_RS22940	COG0730	response to heat
K8M08_RS22955	COG1346	cytolysis
K8M08_RS22965	COG0583	DNA-binding transcription factor activity
K8M08_RS22975	COG1131	(ABC) transporter
K8M08_RS22985	COG1473	amidohydrolase
K8M08_RS22995	COG0785	Cytochrome C biogenesis protein
K8M08_RS23000	COG4846	Membrane protein involved in cytochrome C biogenesis
K8M08_RS23025	COG2226	methyltransferase
K8M08_RS23050	COG0010	Belongs to the arginase family
K8M08_RS23055	COG1329	Transcriptional regulator
K8M08_RS23060	COG1902	pentaerythritol trinitrate reductase activity
K8M08_RS23065	COG0069	glutamate synthase activity
K8M08_RS23075	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K8M08_RS23080	COG0346	lactoylglutathione lyase activity
K8M08_RS23085	COG0400	carboxylic ester hydrolase activity
K8M08_RS23090	COG5002	protein histidine kinase activity
K8M08_RS23100	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8M08_RS23150	COG1396	sequence-specific DNA binding
K8M08_RS23165	COG0318	PFAM AMP-dependent synthetase and ligase
K8M08_RS23170	COG1268	BioY protein
K8M08_RS23175	COG0318	PFAM AMP-dependent synthetase and ligase
K8M08_RS23180	COG0183	Belongs to the thiolase family
K8M08_RS23195	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K8M08_RS23205	COG2211	Major facilitator Superfamily
K8M08_RS23235	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
K8M08_RS23240	COG2274	protein secretion by the type I secretion system
K8M08_RS23250	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8M08_RS23280	COG0824	Thioesterase
K8M08_RS23285	COG4841	protein insertion into membrane
K8M08_RS23305	COG0745	RESPONSE REGULATOR receiver
K8M08_RS23310	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K8M08_RS23315	COG1832	CoA-binding protein
K8M08_RS23320	COG0187	DNA topoisomerase II activity
K8M08_RS23325	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K8M08_RS23330	COG0673	inositol 2-dehydrogenase activity
K8M08_RS23350	COG1131	(ABC) transporter
K8M08_RS23365	COG1595	DNA-templated transcription, initiation
K8M08_RS23375	COG1316	TRANSCRIPTIONal
K8M08_RS23385	COG4166	transmembrane transport
K8M08_RS23390	COG4166	transmembrane transport
K8M08_RS23395	COG4166	transmembrane transport
K8M08_RS23400	COG2226	methyltransferase
K8M08_RS23435	COG0531	amino acid
K8M08_RS23450	COG0697	spore germination
K8M08_RS23455	COG3383	formate dehydrogenase (NAD+) activity
K8M08_RS23460	COG2427	Protein of unknown function (DUF1641)
K8M08_RS23465	COG5609	conserved protein (DUF2294)
K8M08_RS23470	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
K8M08_RS23480	COG2116	formate transmembrane transporter activity
K8M08_RS23485	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K8M08_RS23490	COG0303	'Molybdopterin
K8M08_RS23495	COG0314	molybdopterin synthase activity
K8M08_RS23505	COG0489	protein tyrosine kinase activity
K8M08_RS23520	COG3326	Membrane
K8M08_RS23525	COG2962	Rard protein
K8M08_RS23530	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
K8M08_RS23535	COG1657	PFAM Prenyltransferase squalene oxidase
K8M08_RS23545	COG1028	Short-chain dehydrogenase reductase Sdr
K8M08_RS23550	COG1012	belongs to the aldehyde dehydrogenase family
K8M08_RS23560	COG4145	pantothenate transmembrane transporter activity
K8M08_RS23575	COG0165	Argininosuccinate lyase
K8M08_RS23585	COG1028	Short-chain dehydrogenase reductase Sdr
K8M08_RS23605	COG0494	nUDIX hydrolase
K8M08_RS23615	COG0716	FMN binding
K8M08_RS23655	COG2720	vancomycin resistance protein
K8M08_RS23660	COG2514	catechol 2,3-dioxygenase activity
K8M08_RS23675	COG1285	pathogenesis
K8M08_RS23685	COG3852	Histidine kinase
K8M08_RS23715	COG1309	transcriptional regulator
K8M08_RS23730	COG0825	malonyl-CoA metabolic process
K8M08_RS23740	COG0277	FAD linked oxidase domain protein
K8M08_RS23745	COG0385	Bile acid
K8M08_RS23755	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
K8M08_RS23760	COG2808	Putative FMN-binding domain
K8M08_RS23770	COG0457	Tetratricopeptide repeat
K8M08_RS23780	COG0604	alcohol dehydrogenase
K8M08_RS23785	COG0640	Transcriptional regulator
K8M08_RS23795	COG0584	glycerophosphoryl diester phosphodiesterase
K8M08_RS23825	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K8M08_RS23840	COG3781	membrane
K8M08_RS23865	COG1164	Oligoendopeptidase f
K8M08_RS23870	COG2162	N-hydroxyarylamine O-acetyltransferase activity
K8M08_RS23885	COG1193	negative regulation of DNA recombination
K8M08_RS23905	COG0583	DNA-binding transcription factor activity
K8M08_RS23920	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8M08_RS23940	COG3739	integral membrane protein
K8M08_RS23945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8M08_RS23950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8M08_RS23955	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8M08_RS23970	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
K8M08_RS23975	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
K8M08_RS24005	COG2814	Major facilitator Superfamily
K8M08_RS24010	COG1113	amino acid transport
K8M08_RS24050	COG2072	flavoprotein involved in K transport
K8M08_RS24085	COG3409	Peptidoglycan-binding domain 1 protein
K8M08_RS24085	COG3757	hydrolase, family 25
K8M08_RS24100	COG1151	hydroxylamine reductase activity
K8M08_RS24130	COG3152	Membrane
K8M08_RS24150	COG1280	lysine exporter protein (LysE YggA)
K8M08_RS24160	COG1191	sigma factor activity
K8M08_RS24195	COG1733	regulation of RNA biosynthetic process
K8M08_RS24200	COG2249	NAD(P)H dehydrogenase (quinone) activity
K8M08_RS24205	COG0318	PFAM AMP-dependent synthetase and ligase
K8M08_RS24230	COG0384	phenazine biosynthesis protein PhzF
K8M08_RS24250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8M08_RS24270	COG1733	regulation of RNA biosynthetic process
K8M08_RS24275	COG1733	regulation of RNA biosynthetic process
K8M08_RS24280	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
K8M08_RS24285	COG0673	inositol 2-dehydrogenase activity
K8M08_RS24290	COG2188	Transcriptional regulator
K8M08_RS24295	COG1733	regulation of RNA biosynthetic process
K8M08_RS24300	COG1393	Belongs to the ArsC family
K8M08_RS24325	COG0814	amino acid
K8M08_RS24330	COG0346	lactoylglutathione lyase activity
K8M08_RS24345	COG2814	Major facilitator Superfamily
K8M08_RS24350	COG0656	L-ascorbic acid biosynthetic process
K8M08_RS24365	COG1733	regulation of RNA biosynthetic process
K8M08_RS24370	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K8M08_RS24370	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K8M08_RS24375	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K8M08_RS24375	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K8M08_RS24385	COG0840	transmembrane signaling receptor activity
K8M08_RS24400	COG1028	Short-chain dehydrogenase reductase Sdr
K8M08_RS24415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K8M08_RS24420	COG0604	alcohol dehydrogenase
K8M08_RS24425	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
K8M08_RS24430	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
K8M08_RS24440	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
K8M08_RS24445	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
K8M08_RS24455	COG1070	Carbohydrate kinase
K8M08_RS24460	COG2706	6-phosphogluconolactonase activity
K8M08_RS24465	COG3813	Protein conserved in bacteria
K8M08_RS24470	COG1357	PFAM Pentapeptide repeats (8 copies)
K8M08_RS24475	COG0697	spore germination
K8M08_RS24500	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K8M08_RS24510	COG0789	Transcriptional regulator
K8M08_RS24515	COG1253	flavin adenine dinucleotide binding
K8M08_RS24545	COG0477	Major facilitator Superfamily
K8M08_RS24555	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
K8M08_RS24585	COG0628	permease
K8M08_RS24605	COG1136	(ABC) transporter
K8M08_RS24605	COG0577	efflux transmembrane transporter activity
K8M08_RS24615	COG0110	maltose O-acetyltransferase activity
K8M08_RS24625	COG1940	carbohydrate kinase activity
K8M08_RS24630	COG0346	lactoylglutathione lyase activity
K8M08_RS24650	COG2365	Tyrosine phosphatase family
K8M08_RS24660	COG1011	Hydrolase
K8M08_RS24685	COG1131	(ABC) transporter
K8M08_RS24695	COG1028	Short-chain dehydrogenase reductase Sdr
K8M08_RS24715	COG0778	Nitroreductase
K8M08_RS24720	COG1733	regulation of RNA biosynthetic process
K8M08_RS24740	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
K8M08_RS24755	COG3620	sequence-specific DNA binding
K8M08_RS24770	COG2356	endonuclease I
K8M08_RS24775	COG1288	antiporter activity
K8M08_RS24780	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
K8M08_RS24795	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
K8M08_RS24835	COG2031	fatty acid transporter
K8M08_RS24850	COG1309	transcriptional regulator
K8M08_RS24855	COG2076	Multidrug Resistance protein
K8M08_RS24875	COG1131	(ABC) transporter
K8M08_RS24880	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
K8M08_RS24890	COG2814	Major facilitator Superfamily
K8M08_RS24895	COG1846	Transcriptional regulator
K8M08_RS24910	COG0477	Major facilitator Superfamily
K8M08_RS24920	COG2843	Capsule synthesis protein
K8M08_RS24925	COG1876	peptidase activity
K8M08_RS24955	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8M08_RS24955	COG3409	Peptidoglycan-binding domain 1 protein
K8M08_RS24980	COG0662	Cupin 2, conserved barrel domain protein
K8M08_RS25000	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
K8M08_RS25020	COG0531	amino acid
K8M08_RS25025	COG1522	sequence-specific DNA binding
K8M08_RS25030	COG1335	isochorismatase
K8M08_RS25040	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
K8M08_RS25045	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K8M08_RS25055	COG1760	l-serine dehydratase
K8M08_RS25060	COG1760	l-serine dehydratase
K8M08_RS25065	COG0814	amino acid
K8M08_RS25110	COG1619	proteins homologs of microcin C7 resistance protein MccF
K8M08_RS25135	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8M08_RS25145	COG3850	Histidine kinase
K8M08_RS25145	COG5002	protein histidine kinase activity
K8M08_RS25165	COG0577	efflux transmembrane transporter activity
K8M08_RS25185	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
K8M08_RS25205	COG1476	TRANSCRIPTIONal
K8M08_RS25225	COG2515	1-aminocyclopropane-1-carboxylate deaminase
K8M08_RS25270	COG2814	Major facilitator Superfamily
K8M08_RS25295	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K8M08_RS25305	COG2169	Transcriptional regulator
K8M08_RS25325	COG0346	lactoylglutathione lyase activity
K8M08_RS25340	COG1522	sequence-specific DNA binding
K8M08_RS25345	COG1028	Short-chain dehydrogenase reductase Sdr
K8M08_RS25385	COG1309	transcriptional regulator
K8M08_RS25390	COG2814	Major facilitator Superfamily
K8M08_RS25400	COG1309	transcriptional regulator
K8M08_RS25405	COG3320	Male sterility
K8M08_RS25405	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K8M08_RS25440	COG0519	Catalyzes the synthesis of GMP from XMP
K8M08_RS25450	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
K8M08_RS25460	COG0640	Transcriptional regulator
K8M08_RS25465	COG0346	lactoylglutathione lyase activity
K8M08_RS25470	COG0798	PFAM Bile acid sodium symporter
K8M08_RS25500	COG0577	efflux transmembrane transporter activity
K8M08_RS25505	COG1136	(ABC) transporter
K8M08_RS25510	COG4641	Protein conserved in bacteria
K8M08_RS25515	COG1575	Belongs to the MenA family. Type 1 subfamily
K8M08_RS25525	COG0697	spore germination
K8M08_RS25540	COG5609	conserved protein (DUF2294)
K8M08_RS25545	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K8M08_RS25555	COG0288	reversible hydration of carbon dioxide
K8M08_RS25570	COG0415	Belongs to the DNA photolyase family
K8M08_RS25595	COG0697	spore germination
K8M08_RS25600	COG0814	amino acid
K8M08_RS25640	COG0598	Magnesium transport protein CorA
K8M08_RS25650	COG0583	DNA-binding transcription factor activity
K8M08_RS25670	COG1335	isochorismatase
K8M08_RS25675	COG2267	carboxylic ester hydrolase activity
K8M08_RS25680	COG0753	catalase activity
K8M08_RS25685	COG0737	Belongs to the 5'-nucleotidase family
K8M08_RS25715	COG1115	amino acid carrier protein
K8M08_RS25720	COG2066	Belongs to the glutaminase family
K8M08_RS25725	COG4191	Histidine kinase
K8M08_RS25730	COG0784	Response regulator, receiver
K8M08_RS25735	COG0697	spore germination
K8M08_RS25740	COG0531	amino acid
K8M08_RS25750	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K8M08_RS25755	COG0531	amino acid
K8M08_RS25760	COG0322	excinuclease ABC activity
K8M08_RS25775	COG2207	Transcriptional regulator
K8M08_RS25805	COG5002	protein histidine kinase activity
K8M08_RS25815	COG1396	sequence-specific DNA binding
K8M08_RS25820	COG0252	asparaginase activity
K8M08_RS25825	COG1027	Aspartate ammonia-lyase
K8M08_RS25830	COG1063	alcohol dehydrogenase
K8M08_RS25850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8M08_RS25860	COG0574	Belongs to the PEP-utilizing enzyme family
K8M08_RS25860	COG3848	Pyruvate phosphate dikinase
K8M08_RS25875	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
K8M08_RS25890	COG3314	Sporulation integral membrane protein YlbJ
K8M08_RS25905	COG1960	acyl-CoA dehydrogenase activity
K8M08_RS25910	COG0860	N-Acetylmuramoyl-L-alanine amidase
K8M08_RS25915	COG3142	Participates in the control of copper homeostasis
K8M08_RS25925	COG1414	Transcriptional regulator
K8M08_RS25930	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
K8M08_RS25935	COG1984	allophanate hydrolase subunit 2
K8M08_RS25970	COG0768	penicillin binding
K8M08_RS26005	COG4335	DNA alkylation repair
K8M08_RS26015	COG0833	amino acid
K8M08_RS26025	COG0730	response to heat
K8M08_RS26065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8M08_RS26085	COG0456	acetyltransferase
K8M08_RS26090	COG2207	Transcriptional regulator
K8M08_RS26115	COG1136	(ABC) transporter
K8M08_RS26125	COG4884	unkown
K8M08_RS26125	COG3831	ATPase activity
K8M08_RS26145	COG1846	Transcriptional regulator
K8M08_RS26150	COG0778	Nitroreductase
K8M08_RS26170	COG0659	secondary active sulfate transmembrane transporter activity
K8M08_RS26175	COG2824	Alkylphosphonate utilization operon protein PhnA
K8M08_RS26180	COG0714	Associated with various cellular activities
K8M08_RS26205	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
K8M08_RS26220	COG0753	catalase activity
K8M08_RS26225	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
K8M08_RS26245	COG0714	Associated with various cellular activities
K8M08_RS26270	COG0346	lactoylglutathione lyase activity
K8M08_RS26285	COG3279	Response regulator of the LytR AlgR family
K8M08_RS26295	COG4377	Putative membrane peptidase family (DUF2324)
K8M08_RS26310	COG3655	Transcriptional regulator
K8M08_RS26320	COG1785	Belongs to the alkaline phosphatase family
K8M08_RS26330	COG3239	Fatty acid desaturase
K8M08_RS26345	COG0833	amino acid
K8M08_RS26350	COG1414	Transcriptional regulator
K8M08_RS26355	COG4187	Peptidase family M20/M25/M40
K8M08_RS26360	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K8M08_RS26375	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8M08_RS26395	COG2329	Antibiotic biosynthesis monooxygenase
K8M08_RS26430	COG1070	Carbohydrate kinase
K8M08_RS26435	COG2390	Transcriptional regulator
K8M08_RS26450	COG1172	Belongs to the binding-protein-dependent transport system permease family
K8M08_RS26470	COG1388	LysM domain
K8M08_RS26470	COG3584	3D domain protein
K8M08_RS26500	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
K8M08_RS26500	COG1605	Chorismate mutase
K8M08_RS26510	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
K8M08_RS26515	COG0287	Prephenate dehydrogenase
K8M08_RS26530	COG1309	transcriptional regulator
K8M08_RS26535	COG1033	growth of symbiont in host cell
K8M08_RS26535	COG2409	Drug exporters of the RND superfamily
K8M08_RS26545	COG0488	(ABC) transporter
K8M08_RS26550	COG1368	sulfuric ester hydrolase activity
K8M08_RS26555	COG0861	Integral membrane protein TerC family
K8M08_RS26560	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
K8M08_RS26585	COG0346	lactoylglutathione lyase activity
K8M08_RS26615	COG2318	DinB family
K8M08_RS26620	COG0697	spore germination
K8M08_RS26640	COG2746	aminoglycoside 3-N-acetyltransferase activity
K8M08_RS26685	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K8M08_RS26690	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K8M08_RS26695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K8M08_RS26710	COG0628	permease
K8M08_RS26750	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
K8M08_RS26760	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
K8M08_RS26765	COG0436	Aminotransferase
K8M08_RS26805	COG2226	methyltransferase
K8M08_RS26820	COG2261	transglycosylase associated protein
K8M08_RS26845	COG0477	Major facilitator Superfamily
K8M08_RS26845	COG2814	Major facilitator Superfamily
K8M08_RS26850	COG4533	DNA binding
K8M08_RS26855	COG0789	Transcriptional regulator
K8M08_RS26860	COG1664	Polymer-forming cytoskeletal
K8M08_RS26870	COG2814	Major facilitator Superfamily
K8M08_RS26920	COG1307	EDD domain protein, DegV family
K8M08_RS26930	COG1164	Oligoendopeptidase f
K8M08_RS26965	COG0745	RESPONSE REGULATOR receiver
K8M08_RS26970	COG5002	protein histidine kinase activity
K8M08_RS26970	COG3850	Histidine kinase
K8M08_RS26975	COG2936	dipeptidyl-peptidase activity
K8M08_RS27025	COG4948	Mandelate Racemase Muconate Lactonizing
K8M08_RS27035	COG4166	transmembrane transport
K8M08_RS27055	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
K8M08_RS27070	COG0586	Pfam SNARE associated Golgi protein
K8M08_RS27110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K8M08_RS27115	COG3938	Belongs to the proline racemase family
K8M08_RS27125	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K8M08_RS27260	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8M08_RS27260	COG2207	Transcriptional regulator