locus-tag	class	description
DS740_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DS740_RS00010	COG0592	DNA-directed DNA polymerase activity
DS740_RS00015	COG2501	S4 domain
DS740_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DS740_RS00030	COG0187	DNA topoisomerase II activity
DS740_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DS740_RS00070	COG0517	IMP dehydrogenase activity
DS740_RS00070	COG0516	GMP reductase activity
DS740_RS00075	COG1686	Belongs to the peptidase S11 family
DS740_RS00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
DS740_RS00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
DS740_RS00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DS740_RS00100	COG1428	Deoxynucleoside kinase
DS740_RS00105	COG1428	Deoxynucleoside kinase
DS740_RS00110	COG3858	chitin binding
DS740_RS00110	COG1388	LysM domain
DS740_RS00115	COG1335	isochorismatase
DS740_RS00120	COG0590	tRNA wobble adenosine to inosine editing
DS740_RS00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DS740_RS00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DS740_RS00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DS740_RS00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
DS740_RS00190	COG3853	Toxic anion resistance protein (TelA)
DS740_RS00195	COG1982	Orn Lys Arg decarboxylase major
DS740_RS00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DS740_RS00205	COG3870	Protein conserved in bacteria
DS740_RS00210	COG1728	Protein conserved in bacteria
DS740_RS00215	COG0470	DNA polymerase III
DS740_RS00220	COG1774	PSP1 C-terminal conserved region
DS740_RS00225	COG4467	Involved in initiation control of chromosome replication
DS740_RS00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DS740_RS00235	COG2827	Endonuclease containing a URI domain
DS740_RS00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DS740_RS00245	COG2002	toxin-antitoxin pair type II binding
DS740_RS00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DS740_RS00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DS740_RS00255	COG0084	hydrolase, TatD family'
DS740_RS00260	COG3583	domain protein
DS740_RS00260	COG3584	3D domain protein
DS740_RS00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DS740_RS00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DS740_RS00280	COG4466	Protein conserved in bacteria
DS740_RS00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DS740_RS00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DS740_RS00305	COG2088	sporulation resulting in formation of a cellular spore
DS740_RS00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DS740_RS00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DS740_RS00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DS740_RS00325	COG0193	aminoacyl-tRNA hydrolase activity
DS740_RS00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DS740_RS00340	COG2002	toxin-antitoxin pair type II binding
DS740_RS00345	COG2244	polysaccharide biosynthetic process
DS740_RS00350	COG3956	TIGRFAM MazG family protein
DS740_RS00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DS740_RS00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DS740_RS00375	COG1098	S1 RNA binding domain
DS740_RS00390	COG2208	phosphoserine phosphatase activity
DS740_RS00395	COG2304	oxidoreductase activity
DS740_RS00400	COG0515	serine threonine protein kinase
DS740_RS00405	COG0037	tRNA processing
DS740_RS00410	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DS740_RS00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DS740_RS00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DS740_RS00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DS740_RS00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DS740_RS00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DS740_RS00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DS740_RS00445	COG0512	Glutamine amidotransferase of anthranilate synthase
DS740_RS00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DS740_RS00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DS740_RS00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DS740_RS00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DS740_RS00470	COG1396	sequence-specific DNA binding
DS740_RS00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DS740_RS00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DS740_RS00560	COG4463	regulation of RNA biosynthetic process
DS740_RS00565	COG3880	PFAM UvrB UvrC protein
DS740_RS00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
DS740_RS00575	COG0542	response to heat
DS740_RS00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DS740_RS00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
DS740_RS00590	COG4956	integral membrane protein (PIN domain superfamily)
DS740_RS00595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DS740_RS00600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DS740_RS00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DS740_RS00615	COG1045	serine acetyltransferase
DS740_RS00620	COG0215	cysteine-tRNA ligase activity
DS740_RS00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DS740_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DS740_RS00635	COG3688	RNA-binding protein containing a PIN domain
DS740_RS00640	COG1595	DNA-templated transcription, initiation
DS740_RS00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DS740_RS00655	COG0250	Participates in transcription elongation, termination and antitermination
DS740_RS00665	COG0081	regulation of translation
DS740_RS00670	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DS740_RS00680	COG2813	Specifically methylates the guanine in position
DS740_RS00685	COG0085	RNA polymerase activity
DS740_RS00690	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DS740_RS00695	COG1358	cellular component organization or biogenesis
DS740_RS00700	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DS740_RS00705	COG0049	tRNA binding
DS740_RS00710	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DS740_RS00715	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DS740_RS00720	COG0596	Alpha beta hydrolase
DS740_RS00730	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DS740_RS00735	COG0088	Forms part of the polypeptide exit tunnel
DS740_RS00745	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DS740_RS00760	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DS740_RS00765	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DS740_RS00775	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DS740_RS00780	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DS740_RS00790	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DS740_RS00800	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DS740_RS00805	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DS740_RS00810	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DS740_RS00815	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DS740_RS00825	COG0200	Binds to the 23S rRNA
DS740_RS00830	COG0201	protein transport
DS740_RS00835	COG0563	adenylate kinase activity
DS740_RS00840	COG0024	Methionine aminopeptidase
DS740_RS00845	COG2163	COG2163 Ribosomal protein L14E L6E L27E
DS740_RS00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DS740_RS00860	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DS740_RS00865	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DS740_RS00870	COG0202	RNA polymerase activity
DS740_RS00875	COG0203	ribosomal protein L17
DS740_RS00880	COG1122	ATPase activity
DS740_RS00885	COG1122	ATPase activity
DS740_RS00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DS740_RS00895	COG0101	tRNA pseudouridine synthase activity
DS740_RS00900	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DS740_RS00905	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DS740_RS00910	COG2226	methyltransferase
DS740_RS00920	COG0860	N-Acetylmuramoyl-L-alanine amidase
DS740_RS00925	COG0489	protein tyrosine kinase activity
DS740_RS00935	COG2194	sulfuric ester hydrolase activity
DS740_RS00940	COG0726	polysaccharide deacetylase
DS740_RS01020	COG0659	secondary active sulfate transmembrane transporter activity
DS740_RS01025	COG0385	Bile acid
DS740_RS01030	COG2819	hydrolase of the alpha beta superfamily
DS740_RS01035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DS740_RS01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DS740_RS01045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DS740_RS01050	COG2207	Transcriptional regulator
DS740_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DS740_RS01055	COG3876	Protein conserved in bacteria
DS740_RS01060	COG1472	Belongs to the glycosyl hydrolase 3 family
DS740_RS01065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DS740_RS01070	COG1263	PTS System
DS740_RS01070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DS740_RS01075	COG1737	Transcriptional regulator
DS740_RS01080	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DS740_RS01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DS740_RS01090	COG1683	Conserved Protein
DS740_RS01120	COG1595	DNA-templated transcription, initiation
DS740_RS01125	COG5662	AntiSigma factor
DS740_RS01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DS740_RS01135	COG4856	YbbR-like protein
DS740_RS01140	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DS740_RS01145	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DS740_RS01155	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DS740_RS01160	COG2169	Transcriptional regulator
DS740_RS01165	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DS740_RS01170	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DS740_RS01175	COG3002	Belongs to the UPF0753 family
DS740_RS01180	COG0288	reversible hydration of carbon dioxide
DS740_RS01190	COG5609	conserved protein (DUF2294)
DS740_RS01195	COG0640	Transcriptional regulator
DS740_RS01200	COG2814	Major facilitator Superfamily
DS740_RS01215	COG0515	serine threonine protein kinase
DS740_RS01230	COG1113	amino acid transport
DS740_RS01245	COG2602	Beta-lactamase
DS740_RS01250	COG2124	cytochrome p450
DS740_RS01260	COG0531	amino acid
DS740_RS01265	COG0584	glycerophosphoryl diester phosphodiesterase
DS740_RS01270	COG2271	Major facilitator Superfamily
DS740_RS01285	COG0456	acetyltransferase
DS740_RS01285	COG1846	Transcriptional regulator
DS740_RS01290	COG2271	Major facilitator Superfamily
DS740_RS01300	COG3409	Peptidoglycan-binding domain 1 protein
DS740_RS01305	COG0697	spore germination
DS740_RS01310	COG2207	Transcriptional regulator
DS740_RS01310	COG1917	Cupin 2, conserved barrel domain protein
DS740_RS01315	COG1397	ADP-ribosylglycohydrolase
DS740_RS01320	COG5444	nuclease activity
DS740_RS01325	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DS740_RS01330	COG3591	Belongs to the peptidase S1B family
DS740_RS01340	COG0596	Alpha beta hydrolase
DS740_RS01345	COG1183	phosphatidylcholine synthase activity
DS740_RS01350	COG0586	Pfam SNARE associated Golgi protein
DS740_RS01355	COG0688	phosphatidylethanolamine metabolic process
DS740_RS01365	COG2312	Erythromycin esterase
DS740_RS01370	COG1054	Belongs to the UPF0176 family
DS740_RS01375	COG1301	dicarboxylic acid transport
DS740_RS01380	COG2190	(PTS) system
DS740_RS01380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DS740_RS01380	COG1263	PTS System
DS740_RS01385	COG0363	glucosamine-6-phosphate deaminase activity
DS740_RS01390	COG2188	Transcriptional regulator
DS740_RS01400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DS740_RS01405	COG0833	amino acid
DS740_RS01410	COG2040	homocysteine
DS740_RS01420	COG1115	amino acid carrier protein
DS740_RS01425	COG2066	Belongs to the glutaminase family
DS740_RS01430	COG4191	Histidine kinase
DS740_RS01435	COG0784	Response regulator, receiver
DS740_RS01445	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DS740_RS01450	COG1012	belongs to the aldehyde dehydrogenase family
DS740_RS01455	COG2271	Major facilitator Superfamily
DS740_RS01460	COG4948	Mandelate Racemase Muconate Lactonizing
DS740_RS01465	COG2186	Transcriptional regulator
DS740_RS01470	COG2721	sulfolactate sulfo-lyase activity
DS740_RS01475	COG3173	Aminoglycoside phosphotransferase
DS740_RS01485	COG0697	spore germination
DS740_RS01490	COG0745	RESPONSE REGULATOR receiver
DS740_RS01495	COG2205	protein histidine kinase activity
DS740_RS01500	COG1131	(ABC) transporter
DS740_RS01515	COG3773	Cell wall hydrolase
DS740_RS01520	COG2304	oxidoreductase activity
DS740_RS01530	COG3540	Alkaline phosphatase
DS740_RS01535	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DS740_RS01540	COG0805	protein transport
DS740_RS01545	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DS740_RS01550	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DS740_RS01555	COG0477	Major facilitator Superfamily
DS740_RS01560	COG1309	transcriptional regulator
DS740_RS01565	COG0252	asparaginase activity
DS740_RS01570	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
DS740_RS01575	COG1714	RDD family
DS740_RS01580	COG1405	negative regulation of cell septum assembly
DS740_RS01580	COG3012	SEC-C Motif Domain Protein
DS740_RS01585	COG3290	protein histidine kinase activity
DS740_RS01590	COG3279	Response regulator of the LytR AlgR family
DS740_RS01595	COG4555	ABC transporter
DS740_RS01600	COG1668	transmembrane transport
DS740_RS01605	COG0667	Aldo Keto reductase
DS740_RS01615	COG1595	DNA-templated transcription, initiation
DS740_RS01625	COG1595	DNA-templated transcription, initiation
DS740_RS01630	COG1876	peptidase activity
DS740_RS01635	COG0457	Tetratricopeptide repeat
DS740_RS01640	COG1028	Short-chain dehydrogenase reductase Sdr
DS740_RS01645	COG0366	Alpha amylase catalytic
DS740_RS01650	COG0803	Belongs to the bacterial solute-binding protein 9 family
DS740_RS01655	COG1121	(ABC) transporter
DS740_RS01660	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DS740_RS01665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DS740_RS01670	COG2310	stress, protein
DS740_RS01675	COG2310	stress, protein
DS740_RS01680	COG2310	stress, protein
DS740_RS01685	COG0861	Integral membrane protein TerC family
DS740_RS01695	COG3853	Toxic anion resistance protein (TelA)
DS740_RS01700	COG0477	Major facilitator Superfamily
DS740_RS01710	COG2814	Major facilitator Superfamily
DS740_RS01715	COG0640	Transcriptional regulator
DS740_RS01720	COG0517	IMP dehydrogenase activity
DS740_RS01720	COG4175	Glycine betaine
DS740_RS01725	COG4176	ABC-type proline glycine betaine transport system permease component
DS740_RS01730	COG2113	Glycine betaine
DS740_RS01735	COG1473	amidohydrolase
DS740_RS01740	COG1288	antiporter activity
DS740_RS01750	COG0366	Alpha amylase catalytic
DS740_RS01755	COG0039	L-malate dehydrogenase activity
DS740_RS01760	COG1620	l-lactate permease
DS740_RS01765	COG2814	Major facilitator Superfamily
DS740_RS01770	COG1846	Transcriptional regulator
DS740_RS01775	COG1280	lysine exporter protein (LysE YggA)
DS740_RS01780	COG3403	YqcI/YcgG family
DS740_RS01785	COG1113	amino acid transport
DS740_RS01790	COG3665	Urea carboxylase-associated protein
DS740_RS01795	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DS740_RS01800	COG1660	Displays ATPase and GTPase activities
DS740_RS01805	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DS740_RS01810	COG2226	methyltransferase
DS740_RS01815	COG0583	DNA-binding transcription factor activity
DS740_RS01820	COG3458	cephalosporin-C deacetylase activity
DS740_RS01825	COG3541	Predicted nucleotidyltransferase
DS740_RS01830	COG0506	proline dehydrogenase activity
DS740_RS01835	COG1012	belongs to the aldehyde dehydrogenase family
DS740_RS01840	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DS740_RS01845	COG2508	Transcriptional regulator
DS740_RS01850	COG3689	TIGRFAM TIGR03943 family protein
DS740_RS01855	COG0701	Predicted permease
DS740_RS01860	COG2267	carboxylic ester hydrolase activity
DS740_RS01865	COG0492	ferredoxin-NADP+ reductase activity
DS740_RS01870	COG1587	Uroporphyrinogen-III synthase
DS740_RS01870	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DS740_RS01875	COG2146	nitrite reductase [NAD(P)H] activity
DS740_RS01880	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DS740_RS01885	COG0243	molybdopterin cofactor binding
DS740_RS01890	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DS740_RS01895	COG2223	nitrite transmembrane transporter activity
DS740_RS01900	COG1469	GTP cyclohydrolase I activity
DS740_RS01905	COG1376	ErfK ybiS ycfS ynhG family protein
DS740_RS01915	COG0523	cobalamin synthesis protein
DS740_RS01920	COG0765	amino acid transport
DS740_RS01925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DS740_RS01935	COG1714	RDD family
DS740_RS01945	COG2723	6-phospho-beta-galactosidase activity
DS740_RS01955	COG3209	COG3209 Rhs family protein
DS740_RS01960	COG3290	protein histidine kinase activity
DS740_RS01960	COG0840	transmembrane signaling receptor activity
DS740_RS01965	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DS740_RS01970	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
DS740_RS01975	COG1733	regulation of RNA biosynthetic process
DS740_RS01980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DS740_RS01985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DS740_RS01990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DS740_RS01995	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
DS740_RS02000	COG2814	Major facilitator Superfamily
DS740_RS02010	COG0697	spore germination
DS740_RS02015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DS740_RS02025	COG2364	Membrane
DS740_RS02030	COG1126	abc transporter atp-binding protein
DS740_RS02035	COG0765	amino acid transport
DS740_RS02040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DS740_RS02045	COG0583	DNA-binding transcription factor activity
DS740_RS02050	COG0163	prenyltransferase activity
DS740_RS02055	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DS740_RS02070	COG0596	Alpha beta hydrolase
DS740_RS02075	COG3104	oligopeptide transport
DS740_RS02080	COG5434	Belongs to the glycosyl hydrolase 28 family
DS740_RS02090	COG0697	spore germination
DS740_RS02100	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DS740_RS02105	COG1136	(ABC) transporter
DS740_RS02110	COG0577	efflux transmembrane transporter activity
DS740_RS02115	COG0745	RESPONSE REGULATOR receiver
DS740_RS02120	COG3850	Histidine kinase
DS740_RS02120	COG5002	protein histidine kinase activity
DS740_RS02125	COG0457	Tetratricopeptide repeat
DS740_RS02145	COG0527	aspartate kinase activity
DS740_RS02150	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DS740_RS02155	COG4605	iron ion homeostasis
DS740_RS02160	COG4604	ABC transporter, ATP-binding protein
DS740_RS02165	COG4607	ABC-type enterochelin transport system periplasmic component
DS740_RS02170	COG2814	Major facilitator Superfamily
DS740_RS02175	COG1309	transcriptional regulator
DS740_RS02180	COG0778	Nitroreductase
DS740_RS02185	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
DS740_RS02190	COG0640	Transcriptional regulator
DS740_RS02195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DS740_RS02200	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DS740_RS02205	COG1012	belongs to the aldehyde dehydrogenase family
DS740_RS02210	COG4975	Glucose uptake
DS740_RS02215	COG1028	Short-chain dehydrogenase reductase Sdr
DS740_RS02220	COG4549	nuclear export factor GLE1
DS740_RS02225	COG1276	copper resistance
DS740_RS02225	COG2372	response to copper ion
DS740_RS02230	COG1349	DNA-binding transcription factor activity
DS740_RS02240	COG2213	PTS system mannitol-specific
DS740_RS02245	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DS740_RS02250	COG0246	Mannitol dehydrogenase
DS740_RS02255	COG0473	3-isopropylmalate dehydrogenase activity
DS740_RS02260	COG0681	Belongs to the peptidase S26 family
DS740_RS02265	COG0412	Dienelactone hydrolase
DS740_RS02270	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DS740_RS02280	COG0561	phosphatase activity
DS740_RS02285	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DS740_RS02290	COG1914	H( )-stimulated, divalent metal cation uptake system
DS740_RS02295	COG4336	lyase activity
DS740_RS02300	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DS740_RS02305	COG1984	allophanate hydrolase subunit 2
DS740_RS02310	COG1414	Transcriptional regulator
DS740_RS02315	COG2755	lipolytic protein G-D-S-L family
DS740_RS02325	COG2329	Antibiotic biosynthesis monooxygenase
DS740_RS02330	COG0768	penicillin binding
DS740_RS02335	COG4989	oxidoreductase activity
DS740_RS02340	COG3711	transcriptional antiterminator
DS740_RS02345	COG0318	PFAM AMP-dependent synthetase and ligase
DS740_RS02350	COG2226	methyltransferase
DS740_RS02355	COG1028	Short-chain dehydrogenase reductase Sdr
DS740_RS02360	COG1917	Cupin 2, conserved barrel domain protein
DS740_RS02365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DS740_RS02370	COG3871	stress protein (general stress protein 26)
DS740_RS02380	COG2814	Major facilitator Superfamily
DS740_RS02385	COG1522	sequence-specific DNA binding
DS740_RS02390	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DS740_RS02390	COG0551	DNA topoisomerase type I activity
DS740_RS02395	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
DS740_RS02400	COG3706	GGDEF domain
DS740_RS02405	COG5298	Protein conserved in bacteria
DS740_RS02410	COG1215	transferase activity, transferring glycosyl groups
DS740_RS02420	COG0531	amino acid
DS740_RS02425	COG0494	nUDIX hydrolase
DS740_RS02430	COG0028	Belongs to the TPP enzyme family
DS740_RS02440	COG1914	H( )-stimulated, divalent metal cation uptake system
DS740_RS02445	COG2261	transglycosylase associated protein
DS740_RS02450	COG4876	unkown
DS740_RS02455	COG2217	Heavy metal translocating P-type atpase
DS740_RS02460	COG3729	General stress protein
DS740_RS02465	COG0662	Cupin 2, conserved barrel domain protein
DS740_RS02470	COG2329	Antibiotic biosynthesis monooxygenase
DS740_RS02475	COG3546	catalase activity
DS740_RS02480	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DS740_RS02485	COG3290	protein histidine kinase activity
DS740_RS02490	COG4565	transcriptional regulatory protein
DS740_RS02495	COG1301	dicarboxylic acid transport
DS740_RS02500	COG0628	permease
DS740_RS02505	COG1131	(ABC) transporter
DS740_RS02510	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DS740_RS02520	COG1960	acyl-CoA dehydrogenase activity
DS740_RS02535	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DS740_RS02540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DS740_RS02545	COG1181	Belongs to the D-alanine--D-alanine ligase family
DS740_RS02550	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DS740_RS02560	COG0513	Belongs to the DEAD box helicase family
DS740_RS02565	COG3402	PFAM membrane-flanked domain
DS740_RS02570	COG3428	Bacterial PH domain
DS740_RS02575	COG0705	Rhomboid family
DS740_RS02580	COG0736	holo-[acyl-carrier-protein] synthase activity
DS740_RS02585	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DS740_RS02590	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DS740_RS02595	COG0864	Transcriptional regulator
DS740_RS02600	COG2337	Toxic component of a toxin-antitoxin (TA) module
DS740_RS02605	COG1366	Belongs to the anti-sigma-factor antagonist family
DS740_RS02610	COG1366	Belongs to the anti-sigma-factor antagonist family
DS740_RS02615	COG2172	sigma factor antagonist activity
DS740_RS02620	COG2208	phosphoserine phosphatase activity
DS740_RS02625	COG1366	Belongs to the anti-sigma-factor antagonist family
DS740_RS02630	COG2172	sigma factor antagonist activity
DS740_RS02635	COG1191	sigma factor activity
DS740_RS02640	COG2208	phosphoserine phosphatase activity
DS740_RS02645	COG2183	response to ionizing radiation
DS740_RS02655	COG3091	SprT-like family
DS740_RS02740	COG5444	nuclease activity
DS740_RS02750	COG1476	TRANSCRIPTIONal
DS740_RS02760	COG3239	Fatty acid desaturase
DS740_RS02765	COG1278	Cold shock
DS740_RS02770	COG1329	Transcriptional regulator
DS740_RS02780	COG0697	spore germination
DS740_RS02785	COG2207	Transcriptional regulator
DS740_RS02785	COG1917	Cupin 2, conserved barrel domain protein
DS740_RS02790	COG0697	spore germination
DS740_RS02795	COG2207	Transcriptional regulator
DS740_RS02795	COG3708	Transcriptional regulator
DS740_RS02800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DS740_RS02805	COG0477	Major facilitator Superfamily
DS740_RS02815	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
DS740_RS02835	COG1309	transcriptional regulator
DS740_RS02840	COG0697	spore germination
DS740_RS02845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DS740_RS02850	COG2030	dehydratase
DS740_RS02855	COG3545	Serine hydrolase
DS740_RS02860	COG1733	regulation of RNA biosynthetic process
DS740_RS02865	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DS740_RS02870	COG1733	regulation of RNA biosynthetic process
DS740_RS02875	COG2249	NAD(P)H dehydrogenase (quinone) activity
DS740_RS02880	COG2814	Major facilitator Superfamily
DS740_RS02885	COG1309	transcriptional regulator
DS740_RS02890	COG0640	Transcriptional regulator
DS740_RS02895	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DS740_RS02905	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DS740_RS02910	COG0697	spore germination
DS740_RS02915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DS740_RS02925	COG0640	Transcriptional regulator
DS740_RS02930	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DS740_RS02945	COG4585	Histidine kinase
DS740_RS02950	COG2197	response regulator
DS740_RS02955	COG2409	Drug exporters of the RND superfamily
DS740_RS02960	COG0596	Alpha beta hydrolase
DS740_RS02965	COG1811	Na channel or pump
DS740_RS02970	COG4978	Transcriptional regulator
DS740_RS02970	COG0789	Transcriptional regulator
DS740_RS02975	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DS740_RS02980	COG0778	Nitroreductase
DS740_RS02985	COG0346	lactoylglutathione lyase activity
DS740_RS02990	COG2259	Doxx family
DS740_RS02995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DS740_RS03015	COG2323	membrane
DS740_RS03020	COG2323	membrane
DS740_RS03025	COG0071	Belongs to the small heat shock protein (HSP20) family
DS740_RS03040	COG1309	transcriptional regulator
DS740_RS03050	COG0456	acetyltransferase
DS740_RS03055	COG0488	(ABC) transporter
DS740_RS03060	COG1113	amino acid transport
DS740_RS03065	COG2318	DinB family
DS740_RS03070	COG1846	Transcriptional regulator
DS740_RS03075	COG1033	growth of symbiont in host cell
DS740_RS03075	COG2409	Drug exporters of the RND superfamily
DS740_RS03080	COG0778	Nitroreductase
DS740_RS03085	COG1846	Transcriptional regulator
DS740_RS03090	COG2814	Major facilitator Superfamily
DS740_RS03095	COG0730	response to heat
DS740_RS03100	COG1802	Transcriptional regulator
DS740_RS03105	COG3858	chitin binding
DS740_RS03105	COG1388	LysM domain
DS740_RS03110	COG1819	glycosyl
DS740_RS03120	COG1785	Belongs to the alkaline phosphatase family
DS740_RS03125	COG5646	InterPro IPR014922
DS740_RS03135	COG0454	-acetyltransferase
DS740_RS03140	COG1078	dGTPase activity
DS740_RS03145	COG1388	LysM domain
DS740_RS03150	COG2814	Major facilitator Superfamily
DS740_RS03155	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DS740_RS03160	COG1447	Phosphotransferase system cellobiose-specific component IIA
DS740_RS03165	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DS740_RS03170	COG2723	6-phospho-beta-galactosidase activity
DS740_RS03175	COG2188	Transcriptional regulator
DS740_RS03180	COG1940	carbohydrate kinase activity
DS740_RS03185	COG1482	cell wall glycoprotein biosynthetic process
DS740_RS03190	COG4124	Belongs to the glycosyl hydrolase 26 family
DS740_RS03235	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DS740_RS03240	COG0802	atpase or kinase
DS740_RS03245	COG1214	PFAM Peptidase M22, glycoprotease
DS740_RS03250	COG0456	acetyltransferase
DS740_RS03255	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DS740_RS03260	COG0488	(ABC) transporter
DS740_RS03265	COG0315	cyclic pyranopterin monophosphate synthase activity
DS740_RS03270	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DS740_RS03275	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DS740_RS03280	COG0805	protein transport
DS740_RS03295	COG1266	CAAX protease self-immunity
DS740_RS03305	COG0459	protein refolding
DS740_RS03315	COG1073	alpha beta
DS740_RS03320	COG0457	Tetratricopeptide repeat
DS740_RS03325	COG1063	alcohol dehydrogenase
DS740_RS03330	COG2211	Major facilitator Superfamily
DS740_RS03335	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DS740_RS03340	COG1842	Phage shock protein A
DS740_RS03345	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DS740_RS03350	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
DS740_RS03355	COG4260	virion core protein, lumpy skin disease virus
DS740_RS03365	COG2814	Major facilitator Superfamily
DS740_RS03370	COG1063	alcohol dehydrogenase
DS740_RS03375	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DS740_RS03380	COG0823	Involved in the tonB-independent uptake of proteins
DS740_RS03395	COG2267	carboxylic ester hydrolase activity
DS740_RS03405	COG2132	Multicopper oxidase
DS740_RS03410	COG1113	amino acid transport
DS740_RS03420	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DS740_RS03425	COG0714	Associated with various cellular activities
DS740_RS03430	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
DS740_RS03435	COG1305	Transglutaminase-like
DS740_RS03440	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DS740_RS03440	COG0519	Catalyzes the synthesis of GMP from XMP
DS740_RS03455	COG2252	PERMEase
DS740_RS03460	COG3064	Membrane
DS740_RS03470	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
DS740_RS03480	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DS740_RS03485	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DS740_RS03490	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DS740_RS03495	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DS740_RS03500	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DS740_RS03505	COG0047	phosphoribosylformylglycinamidine synthase activity
DS740_RS03510	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DS740_RS03515	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DS740_RS03520	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DS740_RS03525	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DS740_RS03530	COG0138	bifunctional purine biosynthesis protein purh
DS740_RS03535	COG0151	Belongs to the GarS family
DS740_RS03540	COG1522	sequence-specific DNA binding
DS740_RS03545	COG0531	amino acid
DS740_RS03555	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DS740_RS03560	COG1470	cell adhesion involved in biofilm formation
DS740_RS03565	COG4496	protein, YerC YecD
DS740_RS03570	COG0069	glutamate synthase activity
DS740_RS03575	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
DS740_RS03580	COG0210	DNA helicase
DS740_RS03585	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DS740_RS03590	COG4851	CamS sex pheromone cAM373 precursor
DS740_RS03595	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DS740_RS03600	COG1285	pathogenesis
DS740_RS03605	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DS740_RS03610	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DS740_RS03615	COG0154	amidase activity
DS740_RS03620	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DS740_RS03625	COG1309	transcriptional regulator
DS740_RS03630	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DS740_RS03635	COG1597	lipid kinase activity
DS740_RS03640	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DS740_RS03655	COG5444	nuclease activity
DS740_RS03660	COG3391	amine dehydrogenase activity
DS740_RS03665	COG0457	Tetratricopeptide repeat
DS740_RS03675	COG0217	transcriptional regulatory protein
DS740_RS03685	COG1309	transcriptional regulator
DS740_RS03690	COG3631	Ketosteroid isomerase-related protein
DS740_RS03695	COG0702	epimerase
DS740_RS03710	COG3546	catalase activity
DS740_RS03715	COG0454	-acetyltransferase
DS740_RS03725	COG5578	integral membrane protein
DS740_RS03730	COG2972	Histidine kinase
DS740_RS03735	COG2207	Transcriptional regulator
DS740_RS03735	COG4753	response regulator
DS740_RS03740	COG1653	transport
DS740_RS03745	COG1175	transmembrane transport
DS740_RS03750	COG0395	ABC-type sugar transport system, permease component
DS740_RS03755	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DS740_RS03760	COG2207	Transcriptional regulator
DS740_RS03765	COG2755	lipolytic protein G-D-S-L family
DS740_RS03775	COG5578	integral membrane protein
DS740_RS03780	COG3401	FG-GAP repeat protein
DS740_RS03785	COG3401	FG-GAP repeat protein
DS740_RS03790	COG2755	lipolytic protein G-D-S-L family
DS740_RS03795	COG1874	Beta-galactosidase
DS740_RS03805	COG1653	transport
DS740_RS03810	COG4209	transmembrane transport
DS740_RS03815	COG0395	ABC-type sugar transport system, permease component
DS740_RS03820	COG1486	melibiose metabolic process
DS740_RS03825	COG2323	membrane
DS740_RS03830	COG2329	Antibiotic biosynthesis monooxygenase
DS740_RS03835	COG0346	lactoylglutathione lyase activity
DS740_RS03850	COG5583	Uncharacterized small protein (DUF2292)
DS740_RS03855	COG0670	Belongs to the BI1 family
DS740_RS03860	COG0697	spore germination
DS740_RS03865	COG1846	Transcriptional regulator
DS740_RS03870	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DS740_RS03885	COG2124	cytochrome p450
DS740_RS03885	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DS740_RS03890	COG1368	sulfuric ester hydrolase activity
DS740_RS03895	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DS740_RS03900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DS740_RS03905	COG1442	glycosyl transferase family 8
DS740_RS03910	COG1216	Glycosyl transferase, family 2
DS740_RS03915	COG1442	glycosyl transferase family 8
DS740_RS03920	COG2223	nitrite transmembrane transporter activity
DS740_RS03925	COG1011	Hydrolase
DS740_RS03930	COG0531	amino acid
DS740_RS03935	COG1012	belongs to the aldehyde dehydrogenase family
DS740_RS03940	COG0840	transmembrane signaling receptor activity
DS740_RS03945	COG0488	(ABC) transporter
DS740_RS03955	COG0789	Transcriptional regulator
DS740_RS03960	COG2814	Major facilitator Superfamily
DS740_RS03965	COG1404	Belongs to the peptidase S8 family
DS740_RS03980	COG0488	(ABC) transporter
DS740_RS03985	COG0513	Belongs to the DEAD box helicase family
DS740_RS03990	COG0456	acetyltransferase
DS740_RS03995	COG2130	NADP-dependent
DS740_RS04000	COG1120	ATPase activity
DS740_RS04005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DS740_RS04010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DS740_RS04015	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DS740_RS04035	COG3866	Pectate lyase
DS740_RS04040	COG0471	metal ion transport
DS740_RS04045	COG3290	protein histidine kinase activity
DS740_RS04050	COG4565	transcriptional regulatory protein
DS740_RS04055	COG3181	Tripartite tricarboxylate transporter family receptor
DS740_RS04060	COG2851	Citrate transporter
DS740_RS04065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DS740_RS04070	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
DS740_RS04075	COG1254	Belongs to the acylphosphatase family
DS740_RS04080	COG2258	MOSC domain
DS740_RS04100	COG0024	Methionine aminopeptidase
DS740_RS04105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DS740_RS04105	COG1263	PTS System
DS740_RS04110	COG1368	sulfuric ester hydrolase activity
DS740_RS04125	COG1115	amino acid carrier protein
DS740_RS04130	COG0531	amino acid
DS740_RS04145	COG0697	spore germination
DS740_RS04150	COG1263	PTS System
DS740_RS04150	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DS740_RS04155	COG0366	Alpha amylase catalytic
DS740_RS04160	COG2188	Transcriptional regulator
DS740_RS04165	COG0778	Nitroreductase
DS740_RS04170	COG0737	Belongs to the 5'-nucleotidase family
DS740_RS04175	COG0693	protein deglycase activity
DS740_RS04180	COG2814	Major facilitator Superfamily
DS740_RS04185	COG4840	Belongs to the UPF0435 family
DS740_RS04190	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DS740_RS04195	COG4980	gas vesicle protein
DS740_RS04200	COG1295	ribonuclease BN
DS740_RS04205	COG0477	Major facilitator Superfamily
DS740_RS04210	COG0387	Pfam Sodium calcium exchanger
DS740_RS04220	COG0668	transmembrane transport
DS740_RS04225	COG0535	radical SAM domain protein
DS740_RS04235	COG0726	polysaccharide deacetylase
DS740_RS04240	COG2084	Dehydrogenase
DS740_RS04245	COG0598	Magnesium transport protein CorA
DS740_RS04250	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DS740_RS04255	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DS740_RS04265	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DS740_RS04270	COG4637	Psort location Cytoplasmic, score
DS740_RS04275	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DS740_RS04280	COG0022	dehydrogenase e1 component
DS740_RS04285	COG0508	dehydrogenase complex catalyzes the overall conversion of
DS740_RS04290	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DS740_RS04295	COG3284	Transcriptional regulator
DS740_RS04305	COG1742	UPF0060 membrane protein
DS740_RS04330	COG4842	Belongs to the WXG100 family
DS740_RS04335	COG1486	melibiose metabolic process
DS740_RS04340	COG1737	Transcriptional regulator
DS740_RS04345	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DS740_RS04345	COG1263	PTS System
DS740_RS04350	COG5434	Belongs to the glycosyl hydrolase 28 family
DS740_RS04355	COG1132	(ABC) transporter
DS740_RS04360	COG1132	(ABC) transporter
DS740_RS04365	COG2259	Doxx family
DS740_RS04370	COG2514	catechol 2,3-dioxygenase activity
DS740_RS04375	COG4585	Histidine kinase
DS740_RS04380	COG2197	response regulator
DS740_RS04390	COG1131	(ABC) transporter
DS740_RS04395	COG1511	domain protein
DS740_RS04395	COG0842	Transport permease protein
DS740_RS04400	COG0842	Transport permease protein
DS740_RS04405	COG1695	Transcriptional regulator
DS740_RS04410	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
DS740_RS04415	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
DS740_RS04420	COG2318	DinB family
DS740_RS04425	COG2814	Major facilitator Superfamily
DS740_RS04430	COG1846	Transcriptional regulator
DS740_RS04435	COG0392	lysyltransferase activity
DS740_RS04435	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DS740_RS04440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DS740_RS04445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DS740_RS04450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DS740_RS04455	COG0384	phenazine biosynthesis protein PhzF
DS740_RS04460	COG0778	Nitroreductase
DS740_RS04475	COG1090	epimerase
DS740_RS04480	COG2137	regulation of response to DNA damage stimulus
DS740_RS04490	COG2814	Major facilitator Superfamily
DS740_RS04505	COG3103	Sh3 type 3 domain protein
DS740_RS04510	COG5658	integral membrane protein
DS740_RS04515	COG0596	Alpha beta hydrolase
DS740_RS04520	COG0463	Glycosyl transferase, family 2
DS740_RS04525	COG4485	Bacterial membrane protein, YfhO
DS740_RS04530	COG1988	membrane-bound metal-dependent
DS740_RS04535	COG1194	a g-specific adenine glycosylase
DS740_RS04545	COG1028	Short-chain dehydrogenase reductase Sdr
DS740_RS04560	COG3557	Belongs to the UPF0374 family
DS740_RS04565	COG1132	(ABC) transporter
DS740_RS04570	COG4129	membrane
DS740_RS04575	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DS740_RS04580	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DS740_RS04585	COG0735	belongs to the Fur family
DS740_RS04695	COG4326	sporulation control protein
DS740_RS04705	COG5577	PFAM Coat F domain
DS740_RS04715	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DS740_RS04730	COG0753	catalase activity
DS740_RS04735	COG1116	anion transmembrane transporter activity
DS740_RS04740	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DS740_RS04745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DS740_RS04750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DS740_RS04760	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DS740_RS04770	COG1476	TRANSCRIPTIONal
DS740_RS04780	COG3382	B3 4 domain protein
DS740_RS04785	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DS740_RS04795	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DS740_RS04800	COG0789	Transcriptional regulator
DS740_RS04805	COG1664	Polymer-forming cytoskeletal
DS740_RS04810	COG1664	Polymer-forming cytoskeletal
DS740_RS04815	COG2766	serine protein kinase
DS740_RS04820	COG2718	Belongs to the UPF0229 family
DS740_RS04825	COG1846	Transcriptional regulator
DS740_RS04830	COG1566	PFAM secretion protein HlyD family protein
DS740_RS04835	COG2814	Major facilitator Superfamily
DS740_RS04840	COG0655	NAD(P)H dehydrogenase (quinone) activity
DS740_RS04860	COG1725	Transcriptional regulator
DS740_RS04865	COG1131	(ABC) transporter
DS740_RS04870	COG1131	(ABC) transporter
DS740_RS04875	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DS740_RS04880	COG1278	Cold shock
DS740_RS04890	COG1464	Belongs to the NlpA lipoprotein family
DS740_RS04895	COG3706	GGDEF domain
DS740_RS04900	COG1823	symporter activity
DS740_RS04930	COG5577	PFAM Coat F domain
DS740_RS04935	COG1525	nuclease
DS740_RS04935	COG0737	Belongs to the 5'-nucleotidase family
DS740_RS04935	COG4085	toxin activity
DS740_RS04940	COG3764	Sortase (surface protein transpeptidase)
DS740_RS04945	COG0564	pseudouridine synthase activity
DS740_RS04955	COG0517	IMP dehydrogenase activity
DS740_RS04960	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DS740_RS04965	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DS740_RS04965	COG3153	acetyltransferase
DS740_RS04975	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DS740_RS04980	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
DS740_RS04985	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DS740_RS04990	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DS740_RS04995	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DS740_RS05000	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DS740_RS05005	COG2203	Gaf domain
DS740_RS05005	COG4585	Histidine kinase
DS740_RS05010	COG2197	response regulator
DS740_RS05015	COG0431	NADPH-dependent FMN reductase
DS740_RS05030	COG1388	LysM domain
DS740_RS05030	COG0791	NLP P60 protein
DS740_RS05035	COG1959	2 iron, 2 sulfur cluster binding
DS740_RS05040	COG0668	transmembrane transport
DS740_RS05045	COG2719	SpoVR family
DS740_RS05050	COG1785	Belongs to the alkaline phosphatase family
DS740_RS05055	COG0791	NLP P60 protein
DS740_RS05055	COG1388	LysM domain
DS740_RS05060	COG0583	DNA-binding transcription factor activity
DS740_RS05065	COG0372	Belongs to the citrate synthase family
DS740_RS05070	COG1028	Short-chain dehydrogenase reductase Sdr
DS740_RS05075	COG0531	amino acid
DS740_RS05080	COG0733	neurotransmitter:sodium symporter activity
DS740_RS05085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DS740_RS05090	COG0456	acetyltransferase
DS740_RS05105	COG1595	DNA-templated transcription, initiation
DS740_RS05110	COG0667	Aldo Keto reductase
DS740_RS05115	COG0204	Acyl-transferase
DS740_RS05120	COG1253	flavin adenine dinucleotide binding
DS740_RS05125	COG0789	Transcriptional regulator
DS740_RS05130	COG0436	Aminotransferase
DS740_RS05135	COG1253	flavin adenine dinucleotide binding
DS740_RS05140	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DS740_RS05145	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DS740_RS05150	COG0584	glycerophosphoryl diester phosphodiesterase
DS740_RS05160	COG0668	transmembrane transport
DS740_RS05165	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DS740_RS05170	COG0726	polysaccharide deacetylase
DS740_RS05175	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DS740_RS05180	COG1757	Na H antiporter
DS740_RS05185	COG0589	response to stress
DS740_RS05195	COG1132	(ABC) transporter
DS740_RS05200	COG1132	(ABC) transporter
DS740_RS05205	COG0702	epimerase
DS740_RS05225	COG0189	ligase activity
DS740_RS05230	COG0189	ligase activity
DS740_RS05235	COG4399	Belongs to the UPF0754 family
DS740_RS05240	COG3679	Belongs to the UPF0342 family
DS740_RS05245	COG4335	DNA alkylation repair
DS740_RS05250	COG0561	phosphatase activity
DS740_RS05255	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DS740_RS05260	COG0475	glutathione-regulated potassium exporter activity
DS740_RS05265	COG0490	domain, Protein
DS740_RS05275	COG1024	Enoyl-CoA hydratase
DS740_RS05285	COG4152	abc transporter atp-binding protein
DS740_RS05290	COG1668	transmembrane transport
DS740_RS05295	COG0420	3'-5' exonuclease activity
DS740_RS05300	COG4717	serine-type aminopeptidase activity
DS740_RS05305	COG3481	metal-dependent phosphohydrolase, HD sub domain
DS740_RS05315	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DS740_RS05345	COG1846	Transcriptional regulator
DS740_RS05350	COG4980	gas vesicle protein
DS740_RS05365	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DS740_RS05370	COG0537	adenosine 5'-monophosphoramidase activity
DS740_RS05375	COG1131	(ABC) transporter
DS740_RS05380	COG4473	ABC transporter
DS740_RS05390	COG1473	amidohydrolase
DS740_RS05395	COG3069	C4-dicarboxylate transmembrane transporter activity
DS740_RS05405	COG2329	Antibiotic biosynthesis monooxygenase
DS740_RS05410	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DS740_RS05415	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DS740_RS05420	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DS740_RS05425	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DS740_RS05430	COG1309	transcriptional regulator
DS740_RS05435	COG1511	domain protein
DS740_RS05440	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DS740_RS05445	COG4377	Putative membrane peptidase family (DUF2324)
DS740_RS05455	COG1363	Peptidase, m42
DS740_RS05460	COG4405	Protein conserved in bacteria
DS740_RS05465	COG1301	dicarboxylic acid transport
DS740_RS05475	COG1234	tRNA 3'-trailer cleavage
DS740_RS05480	COG0095	Lipoate-protein ligase
DS740_RS05485	COG0702	epimerase
DS740_RS05490	COG0318	PFAM AMP-dependent synthetase and ligase
DS740_RS05500	COG0501	Belongs to the peptidase M48B family
DS740_RS05510	COG0456	acetyltransferase
DS740_RS05515	COG0604	alcohol dehydrogenase
DS740_RS05520	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DS740_RS05525	COG0406	alpha-ribazole phosphatase activity
DS740_RS05530	COG0183	Belongs to the thiolase family
DS740_RS05535	COG0318	PFAM AMP-dependent synthetase and ligase
DS740_RS05540	COG1268	BioY protein
DS740_RS05545	COG0840	transmembrane signaling receptor activity
DS740_RS05550	COG0723	plastoquinol--plastocyanin reductase activity
DS740_RS05550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DS740_RS05555	COG1028	Short-chain dehydrogenase reductase Sdr
DS740_RS05565	COG4903	ComK protein
DS740_RS05570	COG1028	Short-chain dehydrogenase reductase Sdr
DS740_RS05580	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DS740_RS05595	COG0398	Pfam SNARE associated Golgi protein
DS740_RS05600	COG0681	Belongs to the peptidase S26 family
DS740_RS05605	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DS740_RS05610	COG1846	Transcriptional regulator
DS740_RS05625	COG0738	Major facilitator superfamily
DS740_RS05630	COG0673	inositol 2-dehydrogenase activity
DS740_RS05635	COG0561	phosphatase activity
DS740_RS05640	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DS740_RS05645	COG1609	Transcriptional regulator
DS740_RS05650	COG3180	Ammonia monooxygenase
DS740_RS05655	COG2814	Major facilitator Superfamily
DS740_RS05655	COG0477	Major facilitator Superfamily
DS740_RS05660	COG4533	DNA binding
DS740_RS05670	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
DS740_RS05675	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
DS740_RS05680	COG1074	ATP-dependent DNA helicase activity
DS740_RS05685	COG0420	3'-5' exonuclease activity
DS740_RS05690	COG0419	ATPase involved in DNA repair
DS740_RS05695	COG1403	HNH endonuclease
DS740_RS05735	COG5337	Spore coat protein CotH
DS740_RS05740	COG0179	Fumarylacetoacetate (FAA) hydrolase
DS740_RS05750	COG1404	Belongs to the peptidase S8 family
DS740_RS05760	COG0367	asparagine synthase
DS740_RS05765	COG2318	DinB family
DS740_RS05770	COG1562	ergosterol biosynthetic process
DS740_RS05775	COG0534	Mate efflux family protein
DS740_RS05780	COG2207	Transcriptional regulator
DS740_RS05780	COG1917	Cupin 2, conserved barrel domain protein
DS740_RS05785	COG1609	Transcriptional regulator
DS740_RS05790	COG0673	inositol 2-dehydrogenase activity
DS740_RS05795	COG2318	DinB family
DS740_RS05800	COG1279	arginine transmembrane transporter activity
DS740_RS05805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DS740_RS05810	COG1357	PFAM Pentapeptide repeats (8 copies)
DS740_RS05815	COG2267	carboxylic ester hydrolase activity
DS740_RS05820	COG0529	Catalyzes the synthesis of activated sulfate
DS740_RS05825	COG2046	Belongs to the sulfate adenylyltransferase family
DS740_RS05830	COG0175	sulfate reduction
DS740_RS05835	COG2045	Belongs to the ComB family
DS740_RS05840	COG1809	phosphosulfolactate synthase activity
DS740_RS05845	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DS740_RS05850	COG4948	Mandelate Racemase Muconate Lactonizing
DS740_RS05855	COG2814	Major facilitator Superfamily
DS740_RS05860	COG0454	-acetyltransferase
DS740_RS05865	COG2153	protein acetylation
DS740_RS05870	COG0646	methionine synthase
DS740_RS05870	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DS740_RS05875	COG1666	GTP binding
DS740_RS05880	COG2996	Protein conserved in bacteria
DS740_RS05900	COG1695	Transcriptional regulator
DS740_RS05915	COG3227	Zinc metalloprotease (Elastase)
DS740_RS05920	COG1307	EDD domain protein, DegV family
DS740_RS05925	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DS740_RS05940	COG0561	phosphatase activity
DS740_RS05945	COG1073	alpha beta
DS740_RS05950	COG2151	metal-sulfur cluster biosynthetic enzyme
DS740_RS05960	COG0277	FAD linked oxidase domain protein
DS740_RS05965	COG2271	Major facilitator Superfamily
DS740_RS05970	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DS740_RS05975	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DS740_RS05985	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DS740_RS05990	COG0505	Belongs to the CarA family
DS740_RS05995	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DS740_RS06000	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DS740_RS06015	COG2267	carboxylic ester hydrolase activity
DS740_RS06025	COG1744	ABC transporter substrate-binding protein PnrA-like
DS740_RS06040	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DS740_RS06045	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DS740_RS06050	COG5504	Zn-dependent protease
DS740_RS06055	COG0444	Belongs to the ABC transporter superfamily
DS740_RS06060	COG4608	Belongs to the ABC transporter superfamily
DS740_RS06070	COG0601	transmembrane transport
DS740_RS06075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DS740_RS06085	COG0180	Tryptophanyl-tRNA synthetase
DS740_RS06090	COG4166	transmembrane transport
DS740_RS06095	COG0601	transmembrane transport
DS740_RS06100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DS740_RS06105	COG0444	Belongs to the ABC transporter superfamily
DS740_RS06110	COG4608	Belongs to the ABC transporter superfamily
DS740_RS06115	COG2814	Major facilitator Superfamily
DS740_RS06120	COG0456	acetyltransferase
DS740_RS06125	COG1393	Belongs to the ArsC family
DS740_RS06130	COG0861	Integral membrane protein TerC family
DS740_RS06135	COG4862	establishment of competence for transformation
DS740_RS06140	COG4469	Competence protein
DS740_RS06145	COG1164	Oligoendopeptidase f
DS740_RS06160	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DS740_RS06165	COG2346	COG2346, Truncated hemoglobins
DS740_RS06170	COG0741	lytic transglycosylase activity
DS740_RS06175	COG4116	CYTH
DS740_RS06185	COG2357	RelA SpoT domain protein
DS740_RS06190	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DS740_RS06195	COG0564	pseudouridine synthase activity
DS740_RS06200	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DS740_RS06205	COG0569	domain protein
DS740_RS06205	COG0475	glutathione-regulated potassium exporter activity
DS740_RS06210	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DS740_RS06215	COG0352	thiamine-phosphate diphosphorylase activity
DS740_RS06220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DS740_RS06225	COG2104	thiamine diphosphate biosynthetic process
DS740_RS06230	COG2022	thiamine diphosphate biosynthetic process
DS740_RS06235	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DS740_RS06240	COG0351	phosphomethylpyrimidine kinase
DS740_RS06245	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DS740_RS06300	COG0210	DNA helicase
DS740_RS06310	COG2153	protein acetylation
DS740_RS06315	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
DS740_RS06320	COG2382	esterase
DS740_RS06325	COG0626	cystathionine gamma-synthase activity
DS740_RS06330	COG0626	cystathionine gamma-synthase activity
DS740_RS06335	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DS740_RS06340	COG5505	Protein of unknown function (DUF819)
DS740_RS06355	COG2856	Zn peptidase
DS740_RS06365	COG1525	nuclease
DS740_RS06370	COG1396	sequence-specific DNA binding
DS740_RS06385	COG3645	SOS response
DS740_RS06385	COG3646	Phage regulatory protein
DS740_RS06430	COG3935	DnaD domain protein
DS740_RS06435	COG1484	DNA-dependent DNA replication
DS740_RS06485	COG1595	DNA-templated transcription, initiation
DS740_RS06520	COG5484	DNA packaging
DS740_RS06585	COG5280	Phage tail tape measure protein TP901
DS740_RS06585	COG3953	SLT domain
DS740_RS06590	COG1388	LysM domain
DS740_RS06590	COG0791	NLP P60 protein
DS740_RS06650	COG5632	N-Acetylmuramoyl-L-alanine amidase
DS740_RS06650	COG3409	Peptidoglycan-binding domain 1 protein
DS740_RS06670	COG5444	nuclease activity
DS740_RS06720	COG5444	nuclease activity
DS740_RS06745	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
DS740_RS06750	COG1028	Short-chain dehydrogenase reductase Sdr
DS740_RS06760	COG3711	transcriptional antiterminator
DS740_RS06760	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DS740_RS06765	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DS740_RS06765	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DS740_RS06765	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DS740_RS06770	COG1482	cell wall glycoprotein biosynthetic process
DS740_RS06780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DS740_RS06790	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DS740_RS06810	COG0109	protoheme IX farnesyltransferase activity
DS740_RS06820	COG0726	polysaccharide deacetylase
DS740_RS06840	COG2205	protein histidine kinase activity
DS740_RS06850	COG3383	formate dehydrogenase (NAD+) activity
DS740_RS06855	COG2427	Protein of unknown function (DUF1641)
DS740_RS06875	COG2124	cytochrome p450
DS740_RS06880	COG1819	glycosyl
DS740_RS06900	COG1587	Uroporphyrinogen-III synthase
DS740_RS06905	COG0390	transport system, permease component
DS740_RS06910	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DS740_RS06915	COG0697	spore germination
DS740_RS06920	COG4297	protein containing double-stranded beta helix domain
DS740_RS06930	COG1252	NADH dehydrogenase
DS740_RS06935	COG1904	glucuronate isomerase
DS740_RS06940	COG2211	Major facilitator Superfamily
DS740_RS06945	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
DS740_RS06950	COG1063	alcohol dehydrogenase
DS740_RS06955	COG1312	Catalyzes the dehydration of D-mannonate
DS740_RS06960	COG1028	Short-chain dehydrogenase reductase Sdr
DS740_RS06965	COG2271	Major facilitator Superfamily
DS740_RS06970	COG1609	Transcriptional regulator
DS740_RS06975	COG0246	Mannitol dehydrogenase
DS740_RS06980	COG2721	sulfolactate sulfo-lyase activity
DS740_RS06985	COG0730	response to heat
DS740_RS06990	COG2318	DinB family
DS740_RS06995	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DS740_RS07000	COG0457	Tetratricopeptide repeat
DS740_RS07010	COG2350	Protein conserved in bacteria
DS740_RS07015	COG5632	N-Acetylmuramoyl-L-alanine amidase
DS740_RS07015	COG3409	Peptidoglycan-binding domain 1 protein
DS740_RS07015	COG1388	LysM domain
DS740_RS07025	COG4195	phage-related replication protein
DS740_RS07030	COG3546	catalase activity
DS740_RS07035	COG2856	Zn peptidase
DS740_RS07040	COG1396	sequence-specific DNA binding
DS740_RS07050	COG1522	sequence-specific DNA binding
DS740_RS07055	COG1484	DNA-dependent DNA replication
DS740_RS07075	COG1595	DNA-templated transcription, initiation
DS740_RS07080	COG5484	DNA packaging
DS740_RS07080	COG3728	DNA packaging
DS740_RS07085	COG1783	phage Terminase large subunit
DS740_RS07090	COG5518	Phage portal protein
DS740_RS07095	COG0338	D12 class N6 adenine-specific DNA methyltransferase
DS740_RS07100	COG4653	Phage capsid family
DS740_RS07150	COG3953	SLT domain
DS740_RS07150	COG5412	phage tail tape measure protein
DS740_RS07155	COG1652	LysM domain
DS740_RS07160	COG4193	domain, Protein
DS740_RS07170	COG3628	GPW Gp25 family protein
DS740_RS07175	COG3299	homolog of phage Mu protein gp47
DS740_RS07180	COG3778	Protein conserved in bacteria
DS740_RS07220	COG3409	Peptidoglycan-binding domain 1 protein
DS740_RS07220	COG5632	N-Acetylmuramoyl-L-alanine amidase
DS740_RS07235	COG0306	phosphate transporter
DS740_RS07240	COG1392	Phosphate transport regulator
DS740_RS07245	COG0531	amino acid
DS740_RS07250	COG0346	lactoylglutathione lyase activity
DS740_RS07255	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DS740_RS07260	COG0463	Glycosyl transferase, family 2
DS740_RS07265	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DS740_RS07270	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DS740_RS07275	COG2362	D-Aminopeptidase
DS740_RS07280	COG0601	transmembrane transport
DS740_RS07285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DS740_RS07290	COG0444	Belongs to the ABC transporter superfamily
DS740_RS07295	COG4166	transmembrane transport
DS740_RS07300	COG1619	proteins homologs of microcin C7 resistance protein MccF
DS740_RS07305	COG4948	Mandelate Racemase Muconate Lactonizing
DS740_RS07310	COG0791	NLP P60 protein
DS740_RS07315	COG4608	Belongs to the ABC transporter superfamily
DS740_RS07320	COG2706	6-phosphogluconolactonase activity
DS740_RS07325	COG1834	amidinotransferase
DS740_RS07330	COG1607	acyl-coa hydrolase
DS740_RS07335	COG1017	nitric oxide dioxygenase activity
DS740_RS07335	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DS740_RS07345	COG2323	membrane
DS740_RS07350	COG2318	DinB family
DS740_RS07355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DS740_RS07360	COG2076	Multidrug Resistance protein
DS740_RS07365	COG2076	Multidrug Resistance protein
DS740_RS07370	COG0788	formyltetrahydrofolate deformylase activity
DS740_RS07375	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DS740_RS07380	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DS740_RS07385	COG1764	response to oxidative stress
DS740_RS07390	COG1846	Transcriptional regulator
DS740_RS07395	COG1764	response to oxidative stress
DS740_RS07405	COG0590	tRNA wobble adenosine to inosine editing
DS740_RS07410	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DS740_RS07415	COG1404	Belongs to the peptidase S8 family
DS740_RS07420	COG1366	Belongs to the anti-sigma-factor antagonist family
DS740_RS07425	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DS740_RS07430	COG1122	ATPase activity
DS740_RS07435	COG4721	ABC-type cobalt transport system, permease component
DS740_RS07445	COG0745	RESPONSE REGULATOR receiver
DS740_RS07450	COG5002	protein histidine kinase activity
DS740_RS07450	COG3850	Histidine kinase
DS740_RS07455	COG3212	peptidase
DS740_RS07460	COG3212	peptidase
DS740_RS07475	COG2239	Acts as a magnesium transporter
DS740_RS07480	COG0789	Transcriptional regulator
DS740_RS07495	COG1846	Transcriptional regulator
DS740_RS07500	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DS740_RS07505	COG0726	polysaccharide deacetylase
DS740_RS07510	COG1408	metallophosphoesterase
DS740_RS07520	COG0463	Glycosyl transferase, family 2
DS740_RS07525	COG1793	dna ligase
DS740_RS07525	COG3285	dna ligase
DS740_RS07530	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DS740_RS07535	COG5001	Diguanylate cyclase
DS740_RS07535	COG3300	MHYT domain
DS740_RS07540	COG0586	Pfam SNARE associated Golgi protein
DS740_RS07545	COG0861	Integral membrane protein TerC family
DS740_RS07550	COG1191	sigma factor activity
DS740_RS07570	COG0501	Belongs to the peptidase M48B family
DS740_RS07575	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DS740_RS07590	COG3594	Acyltransferase
DS740_RS07595	COG5002	protein histidine kinase activity
DS740_RS07600	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DS740_RS07605	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DS740_RS07610	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
DS740_RS07615	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DS740_RS07620	COG0436	Aminotransferase
DS740_RS07625	COG1850	ribulose-bisphosphate carboxylase activity
DS740_RS07630	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
DS740_RS07635	COG0235	Class ii aldolase
DS740_RS07640	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
DS740_RS07645	COG3339	Conserved Protein
DS740_RS07660	COG3852	Histidine kinase
DS740_RS07665	COG1846	Transcriptional regulator
DS740_RS07670	COG1360	Flagellar Motor Protein
DS740_RS07675	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DS740_RS07680	COG0542	response to heat
DS740_RS07685	COG3949	Membrane
DS740_RS07690	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DS740_RS07695	COG0720	synthase
DS740_RS07700	COG0602	queuosine metabolic process
DS740_RS07705	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DS740_RS07710	COG1733	regulation of RNA biosynthetic process
DS740_RS07715	COG1028	Short-chain dehydrogenase reductase Sdr
DS740_RS07720	COG1388	LysM domain
DS740_RS07720	COG4641	Protein conserved in bacteria
DS740_RS07725	COG1388	LysM domain
DS740_RS07730	COG3858	chitin binding
DS740_RS07735	COG3858	chitin binding
DS740_RS07745	COG4873	Protein conserved in bacteria
DS740_RS07755	COG3773	Cell wall hydrolase
DS740_RS07760	COG2244	polysaccharide biosynthetic process
DS740_RS07765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DS740_RS07770	COG2217	Heavy metal translocating P-type atpase
DS740_RS07780	COG0006	proline dipeptidase activity
DS740_RS07785	COG1609	Transcriptional regulator
DS740_RS07790	COG3711	transcriptional antiterminator
DS740_RS07795	COG1263	PTS System
DS740_RS07795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DS740_RS07795	COG2190	(PTS) system
DS740_RS07800	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DS740_RS07805	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DS740_RS07815	COG1533	DNA photolyase activity
DS740_RS07820	COG0456	acetyltransferase
DS740_RS07825	COG0840	transmembrane signaling receptor activity
DS740_RS07830	COG2084	Dehydrogenase
DS740_RS07835	COG4257	antibiotic catabolic process
DS740_RS07840	COG2340	Cysteine-rich secretory protein family
DS740_RS07845	COG0768	penicillin binding
DS740_RS07850	COG4191	Histidine kinase
DS740_RS07855	COG0436	Aminotransferase
DS740_RS07865	COG0784	Response regulator, receiver
DS740_RS07865	COG0835	chemotaxis
DS740_RS07875	COG2814	Major facilitator Superfamily
DS740_RS07880	COG1376	ErfK ybiS ycfS ynhG family protein
DS740_RS07885	COG1408	metallophosphoesterase
DS740_RS07890	COG1028	Short-chain dehydrogenase reductase Sdr
DS740_RS07895	COG2200	EAL domain
DS740_RS07900	COG4703	Protein of unknown function (DUF1797)
DS740_RS07905	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
DS740_RS07915	COG0517	IMP dehydrogenase activity
DS740_RS07920	COG0583	DNA-binding transcription factor activity
DS740_RS07925	COG0716	FMN binding
DS740_RS07935	COG0716	FMN binding
DS740_RS07940	COG2171	N-acyltransferase activity
DS740_RS07945	COG1473	amidohydrolase
DS740_RS07955	COG0668	transmembrane transport
DS740_RS07960	COG0450	alkyl hydroperoxide reductase
DS740_RS07965	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DS740_RS07980	COG0746	molybdenum cofactor guanylyltransferase activity
DS740_RS07985	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DS740_RS07990	COG0303	'Molybdopterin
DS740_RS07995	COG1763	Mo-molybdopterin cofactor biosynthetic process
DS740_RS08000	COG0314	molybdopterin synthase activity
DS740_RS08005	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DS740_RS08010	COG1132	(ABC) transporter
DS740_RS08015	COG1132	(ABC) transporter
DS740_RS08025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DS740_RS08030	COG1136	(ABC) transporter
DS740_RS08035	COG0577	efflux transmembrane transporter activity
DS740_RS08040	COG1349	DNA-binding transcription factor activity
DS740_RS08045	COG1105	Belongs to the carbohydrate kinase PfkB family
DS740_RS08050	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DS740_RS08050	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DS740_RS08050	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DS740_RS08055	COG0681	Belongs to the peptidase S26 family
DS740_RS08065	COG0488	(ABC) transporter
DS740_RS08070	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DS740_RS08075	COG2309	aminopeptidase activity
DS740_RS08085	COG1077	Cell shape determining protein MreB Mrl
DS740_RS08090	COG2002	toxin-antitoxin pair type II binding
DS740_RS08095	COG3852	Histidine kinase
DS740_RS08100	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
DS740_RS08100	COG2105	PFAM AIG2 family protein
DS740_RS08105	COG0569	domain protein
DS740_RS08110	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DS740_RS08115	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DS740_RS08120	COG5503	Protein of unknown function (DUF1447)
DS740_RS08125	COG0561	phosphatase activity
DS740_RS08130	COG0242	peptide deformylase activity
DS740_RS08140	COG0497	DNA recombination
DS740_RS08145	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DS740_RS08150	COG0022	dehydrogenase e1 component
DS740_RS08155	COG0508	dehydrogenase complex catalyzes the overall conversion of
DS740_RS08160	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DS740_RS08165	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DS740_RS08175	COG1982	Orn Lys Arg decarboxylase major
DS740_RS08180	COG4476	Belongs to the UPF0223 family
DS740_RS08185	COG4493	Belongs to the UPF0637 family
DS740_RS08195	COG0483	inositol monophosphate 1-phosphatase activity
DS740_RS08205	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DS740_RS08245	COG1217	gtp-binding protein TYPA
DS740_RS08255	COG4896	Protein conserved in bacteria
DS740_RS08265	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DS740_RS08270	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DS740_RS08275	COG2066	Belongs to the glutaminase family
DS740_RS08280	COG4838	Belongs to the UPF0358 family
DS740_RS08285	COG0772	Belongs to the SEDS family
DS740_RS08290	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DS740_RS08295	COG1612	heme a metabolic process
DS740_RS08300	COG0109	protoheme IX farnesyltransferase activity
DS740_RS08305	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DS740_RS08305	COG2010	Cytochrome c
DS740_RS08310	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DS740_RS08315	COG1845	cytochrome c oxidase, subunit III
DS740_RS08320	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DS740_RS08325	COG3336	cytochrome c oxidase
DS740_RS08335	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
DS740_RS08340	COG2340	Cysteine-rich secretory protein family
DS740_RS08355	COG3679	Belongs to the UPF0342 family
DS740_RS08360	COG4471	UPF0298 protein
DS740_RS08365	COG0742	ribosomal rna small subunit methyltransferase
DS740_RS08370	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DS740_RS08375	COG3314	Sporulation integral membrane protein YlbJ
DS740_RS08380	COG1752	Esterase of the alpha-beta hydrolase superfamily
DS740_RS08385	COG3480	Lon protease (S16) C-terminal proteolytic domain
DS740_RS08390	COG1323	Belongs to the UPF0348 family
DS740_RS08400	COG1399	metal-binding, possibly nucleic acid-binding protein
DS740_RS08415	COG0454	-acetyltransferase
DS740_RS08420	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DS740_RS08425	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
DS740_RS08430	COG2001	Belongs to the MraZ family
DS740_RS08435	COG0275	rRNA processing
DS740_RS08440	COG4839	cell division protein FtsL
DS740_RS08445	COG0768	penicillin binding
DS740_RS08450	COG0768	penicillin binding
DS740_RS08455	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DS740_RS08460	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DS740_RS08465	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DS740_RS08470	COG0772	Belongs to the SEDS family
DS740_RS08475	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DS740_RS08480	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DS740_RS08485	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DS740_RS08490	COG3879	Bacterial protein of unknown function (DUF881)
DS740_RS08495	COG3879	Bacterial protein of unknown function (DUF881)
DS740_RS08500	COG3856	small basic protein
DS740_RS08505	COG0849	cell division
DS740_RS08510	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DS740_RS08515	COG4412	M6 family metalloprotease domain protein
DS740_RS08515	COG1404	Belongs to the peptidase S8 family
DS740_RS08525	COG1191	sigma factor activity
DS740_RS08530	COG1191	sigma factor activity
DS740_RS08535	COG1119	ATPase activity
DS740_RS08540	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DS740_RS08545	COG1873	PFAM PRC-barrel domain
DS740_RS08550	COG1496	oxidoreductase activity
DS740_RS08555	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DS740_RS08560	COG1799	cell septum assembly
DS740_RS08565	COG0762	integral membrane protein
DS740_RS08570	COG2302	S4 RNA-binding domain
DS740_RS08575	COG3599	regulation of cell shape
DS740_RS08580	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DS740_RS08585	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DS740_RS08590	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DS740_RS08595	COG0564	pseudouridine synthase activity
DS740_RS08600	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DS740_RS08605	COG2233	PERMEase
DS740_RS08610	COG0540	Belongs to the ATCase OTCase family
DS740_RS08615	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DS740_RS08620	COG0505	Belongs to the CarA family
DS740_RS08625	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DS740_RS08630	COG0543	2 iron, 2 sulfur cluster binding
DS740_RS08635	COG0167	dihydroorotate dehydrogenase activity
DS740_RS08640	COG0284	orotidine-5'-phosphate decarboxylase activity
DS740_RS08645	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DS740_RS08650	COG0175	sulfate reduction
DS740_RS08655	COG0306	phosphate transporter
DS740_RS08660	COG2046	Belongs to the sulfate adenylyltransferase family
DS740_RS08665	COG0529	Catalyzes the synthesis of activated sulfate
DS740_RS08670	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DS740_RS08675	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
DS740_RS08680	COG1648	precorrin-2 dehydrogenase activity
DS740_RS08685	COG1293	RNA-binding protein homologous to eukaryotic snRNP
DS740_RS08690	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DS740_RS08695	COG1561	YicC-like family, N-terminal region
DS740_RS08705	COG0194	GDP metabolic process
DS740_RS08710	COG1758	RNA polymerase activity
DS740_RS08715	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DS740_RS08720	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DS740_RS08725	COG0242	peptide deformylase activity
DS740_RS08730	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DS740_RS08735	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DS740_RS08735	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DS740_RS08740	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DS740_RS08745	COG0631	protein serine/threonine phosphatase activity
DS740_RS08750	COG2815	serine threonine protein kinase
DS740_RS08750	COG0515	serine threonine protein kinase
DS740_RS08755	COG1162	GTPase activity
DS740_RS08760	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DS740_RS08765	COG1564	THIamine pyrophosphokinase
DS740_RS08775	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DS740_RS08780	COG1302	Protein conserved in bacteria
DS740_RS08785	COG1461	Dihydroxyacetone kinase
DS740_RS08790	COG1760	l-serine dehydratase
DS740_RS08795	COG1760	l-serine dehydratase
DS740_RS08800	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DS740_RS08805	COG1349	DNA-binding transcription factor activity
DS740_RS08805	COG2050	protein possibly involved in aromatic compounds catabolism
DS740_RS08810	COG0416	fatty acid biosynthetic process
DS740_RS08815	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DS740_RS08820	COG1028	Short-chain dehydrogenase reductase Sdr
DS740_RS08830	COG0571	ribonuclease III activity
DS740_RS08835	COG1196	nuclear chromosome segregation
DS740_RS08840	COG0552	protein localization to endoplasmic reticulum
DS740_RS08850	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
DS740_RS08855	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DS740_RS08860	COG0228	four-way junction DNA binding
DS740_RS08865	COG1837	Belongs to the UPF0109 family
DS740_RS08875	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DS740_RS08880	COG0336	Belongs to the RNA methyltransferase TrmD family
DS740_RS08885	COG0335	large ribosomal subunit rRNA binding
DS740_RS08890	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DS740_RS08895	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DS740_RS08905	COG2257	FlhB HrpN YscU SpaS Family
DS740_RS08910	COG0045	succinate-CoA ligase (ADP-forming) activity
DS740_RS08915	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DS740_RS08920	COG0758	DNA mediated transformation
DS740_RS08925	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DS740_RS08930	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DS740_RS08935	COG4974	Belongs to the 'phage' integrase family
DS740_RS08940	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DS740_RS08945	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DS740_RS08950	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DS740_RS08955	COG1815	bacterial-type flagellum-dependent cell motility
DS740_RS08960	COG1558	bacterial-type flagellum-dependent cell motility
DS740_RS08965	COG1677	Flagellar hook-basal body complex protein FliE
DS740_RS08970	COG1766	The M ring may be actively involved in energy transduction
DS740_RS08975	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DS740_RS08980	COG1317	bacterial-type flagellum organization
DS740_RS08985	COG1157	protein secretion by the type III secretion system
DS740_RS08990	COG2882	bacterial-type flagellum organization
DS740_RS08995	COG3334	PFAM MgtE intracellular
DS740_RS09000	COG3144	bacterial-type flagellum assembly
DS740_RS09005	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DS740_RS09010	COG4786	Flagellar basal body rod
DS740_RS09015	COG1582	Flagellar protein (FlbD)
DS740_RS09020	COG1580	Controls the rotational direction of flagella during chemotaxis
DS740_RS09025	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DS740_RS09030	COG1776	CheC inhibitor of MCP methylation
DS740_RS09030	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DS740_RS09035	COG2201	protein-glutamate methylesterase activity
DS740_RS09040	COG3190	flagellar
DS740_RS09045	COG1338	Plays a role in the flagellum-specific transport system
DS740_RS09050	COG1987	bacterial-type flagellum assembly
DS740_RS09055	COG1684	flagellar biosynthetic protein fliR
DS740_RS09060	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DS740_RS09065	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DS740_RS09070	COG1419	protein localization to endoplasmic reticulum
DS740_RS09075	COG0455	bacterial-type flagellum organization
DS740_RS09080	COG2201	protein-glutamate methylesterase activity
DS740_RS09085	COG2198	Histidine kinase
DS740_RS09085	COG0643	Histidine kinase
DS740_RS09090	COG0835	chemotaxis
DS740_RS09095	COG1776	CheC inhibitor of MCP methylation
DS740_RS09100	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
DS740_RS09105	COG1191	sigma factor activity
DS740_RS09115	COG0052	Belongs to the universal ribosomal protein uS2 family
DS740_RS09120	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DS740_RS09125	COG0528	UMP kinase activity
DS740_RS09130	COG0233	cytoplasmic translational termination
DS740_RS09135	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DS740_RS09140	COG4589	Belongs to the CDS family
DS740_RS09145	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DS740_RS09150	COG0750	zinc metalloprotease
DS740_RS09155	COG0442	prolyl-tRNA aminoacylation
DS740_RS09160	COG2176	DNA-directed DNA polymerase activity
DS740_RS09185	COG0779	Required for maturation of 30S ribosomal subunits
DS740_RS09190	COG0195	Participates in both transcription termination and antitermination
DS740_RS09195	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DS740_RS09200	COG1358	cellular component organization or biogenesis
DS740_RS09205	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DS740_RS09210	COG1550	Protein conserved in bacteria
DS740_RS09215	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DS740_RS09220	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DS740_RS09225	COG0196	riboflavin kinase activity
DS740_RS09230	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DS740_RS09235	COG1185	polyribonucleotide nucleotidyltransferase activity
DS740_RS09240	COG0726	polysaccharide deacetylase
DS740_RS09245	COG0612	Peptidase, M16
DS740_RS09250	COG1873	PFAM PRC-barrel domain
DS740_RS09255	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DS740_RS09260	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DS740_RS09265	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DS740_RS09270	COG0527	aspartate kinase activity
DS740_RS09275	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DS740_RS09280	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DS740_RS09285	COG0740	serine-type endopeptidase activity
DS740_RS09295	COG4980	gas vesicle protein
DS740_RS09295	COG1674	ftsk spoiiie
DS740_RS09300	COG2188	Transcriptional regulator
DS740_RS09305	COG2814	Major facilitator Superfamily
DS740_RS09310	COG0612	Peptidase, M16
DS740_RS09315	COG0612	Peptidase, M16
DS740_RS09320	COG0300	oxidoreductase activity
DS740_RS09335	COG1426	Protein conserved in bacteria
DS740_RS09340	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DS740_RS09345	COG1546	Belongs to the CinA family
DS740_RS09345	COG1058	Belongs to the CinA family
DS740_RS09350	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DS740_RS09355	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DS740_RS09360	COG1418	mRNA catabolic process
DS740_RS09365	COG1692	metallophosphoesterase
DS740_RS09370	COG2359	stage V sporulation protein S
DS740_RS09375	COG1063	alcohol dehydrogenase
DS740_RS09380	COG0156	8-amino-7-oxononanoate synthase activity
DS740_RS09385	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DS740_RS09390	COG4550	Control of competence regulator ComK, YlbF/YmcA
DS740_RS09400	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DS740_RS09405	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DS740_RS09420	COG3226	Transcriptional regulator
DS740_RS09425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DS740_RS09435	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DS740_RS09440	COG3321	synthase
DS740_RS09445	COG2070	2-Nitropropane dioxygenase
DS740_RS09445	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DS740_RS09450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DS740_RS09455	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DS740_RS09460	COG3425	synthase
DS740_RS09465	COG1024	Enoyl-CoA hydratase
DS740_RS09470	COG1024	Enoyl-CoA hydratase
DS740_RS09475	COG0318	PFAM AMP-dependent synthetase and ligase
DS740_RS09475	COG0300	oxidoreductase activity
DS740_RS09475	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DS740_RS09475	COG1028	Short-chain dehydrogenase reductase Sdr
DS740_RS09475	COG3321	synthase
DS740_RS09480	COG3321	synthase
DS740_RS09480	COG0300	oxidoreductase activity
DS740_RS09480	COG4221	oxidoreductase activity
DS740_RS09480	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DS740_RS09485	COG1028	Short-chain dehydrogenase reductase Sdr
DS740_RS09485	COG3321	synthase
DS740_RS09485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DS740_RS09485	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DS740_RS09485	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DS740_RS09490	COG4221	oxidoreductase activity
DS740_RS09490	COG3321	synthase
DS740_RS09490	COG1028	Short-chain dehydrogenase reductase Sdr
DS740_RS09490	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DS740_RS09495	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
DS740_RS09495	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DS740_RS09495	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DS740_RS09495	COG3321	synthase
DS740_RS09500	COG2124	cytochrome p450
DS740_RS09510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DS740_RS09515	COG1404	Belongs to the peptidase S8 family
DS740_RS09525	COG4195	phage-related replication protein
DS740_RS09530	COG1764	response to oxidative stress
DS740_RS09535	COG2076	Multidrug Resistance protein
DS740_RS09540	COG2076	Multidrug Resistance protein
DS740_RS09555	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DS740_RS09560	COG1923	regulation of RNA biosynthetic process
DS740_RS09575	COG1780	Probably involved in ribonucleotide reductase function
DS740_RS09580	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DS740_RS09585	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DS740_RS09590	COG4112	unkown
DS740_RS09595	COG0860	N-Acetylmuramoyl-L-alanine amidase
DS740_RS09605	COG0464	growth
DS740_RS09610	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DS740_RS09615	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
DS740_RS09620	COG0789	Transcriptional regulator
DS740_RS09625	COG0174	glutamine synthetase
DS740_RS09650	COG4282	regulation of fungal-type cell wall biogenesis
DS740_RS09660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DS740_RS09690	COG0135	phosphoribosylanthranilate isomerase activity
DS740_RS09695	COG2211	Major facilitator Superfamily
DS740_RS09700	COG3507	Belongs to the glycosyl hydrolase 43 family
DS740_RS09705	COG1940	carbohydrate kinase activity
DS740_RS09710	COG2115	Belongs to the xylose isomerase family
DS740_RS09715	COG1070	Carbohydrate kinase
DS740_RS09730	COG2814	Major facilitator Superfamily
DS740_RS09735	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DS740_RS09750	COG0756	dUTP diphosphatase activity
DS740_RS09785	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DS740_RS09795	COG3832	glyoxalase III activity
DS740_RS09805	COG0697	spore germination
DS740_RS09810	COG0531	amino acid
DS740_RS09840	COG4195	phage-related replication protein
DS740_RS09850	COG0346	lactoylglutathione lyase activity
DS740_RS09860	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DS740_RS09865	COG1388	LysM domain
DS740_RS09870	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DS740_RS09875	COG4224	UPF0291 protein
DS740_RS09880	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DS740_RS09890	COG3763	UPF0154 protein
DS740_RS09900	COG0785	Cytochrome C biogenesis protein
DS740_RS09905	COG2201	protein-glutamate methylesterase activity
DS740_RS09910	COG4846	Membrane protein involved in cytochrome C biogenesis
DS740_RS09920	COG0071	Belongs to the small heat shock protein (HSP20) family
DS740_RS09935	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DS740_RS09940	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DS740_RS09960	COG0824	Thioesterase
DS740_RS09970	COG4841	protein insertion into membrane
DS740_RS09975	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DS740_RS09980	COG1832	CoA-binding protein
DS740_RS09985	COG0187	DNA topoisomerase II activity
DS740_RS09990	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DS740_RS10000	COG1115	amino acid carrier protein
DS740_RS10005	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DS740_RS10015	COG5520	Belongs to the glycosyl hydrolase 30 family
DS740_RS10020	COG3507	Belongs to the glycosyl hydrolase 43 family
DS740_RS10025	COG2246	polysaccharide biosynthetic process
DS740_RS10030	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DS740_RS10035	COG0586	Pfam SNARE associated Golgi protein
DS740_RS10040	COG2404	hydrolase activity, acting on ester bonds
DS740_RS10045	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DS740_RS10050	COG1024	Enoyl-CoA hydratase
DS740_RS10055	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DS740_RS10060	COG0511	ligase activity, forming carbon-carbon bonds
DS740_RS10065	COG0439	Biotin carboxylase
DS740_RS10070	COG0318	PFAM AMP-dependent synthetase and ligase
DS740_RS10075	COG1960	acyl-CoA dehydrogenase activity
DS740_RS10085	COG1649	PFAM Uncharacterised BCR, COG1649
DS740_RS10095	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
DS740_RS10095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DS740_RS10100	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DS740_RS10105	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DS740_RS10110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DS740_RS10115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DS740_RS10120	COG2027	D-alanyl-D-alanine carboxypeptidase
DS740_RS10125	COG2017	converts alpha-aldose to the beta-anomer
DS740_RS10130	COG0534	Mate efflux family protein
DS740_RS10145	COG0582	viral genome integration into host DNA
DS740_RS10150	COG0166	Belongs to the GPI family
DS740_RS10155	COG0405	Gamma-glutamyltransferase
DS740_RS10160	COG0583	DNA-binding transcription factor activity
DS740_RS10170	COG0493	'glutamate synthase
DS740_RS10175	COG0067	glutamate synthase
DS740_RS10175	COG0069	glutamate synthase activity
DS740_RS10175	COG0070	glutamate synthase
DS740_RS10180	COG0583	DNA-binding transcription factor activity
DS740_RS10185	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DS740_RS10190	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DS740_RS10200	COG0300	oxidoreductase activity
DS740_RS10205	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
DS740_RS10215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DS740_RS10230	COG1131	(ABC) transporter
DS740_RS10240	COG2814	Major facilitator Superfamily
DS740_RS10245	COG1070	Carbohydrate kinase
DS740_RS10250	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DS740_RS10255	COG0243	molybdopterin cofactor binding
DS740_RS10265	COG2814	Major facilitator Superfamily
DS740_RS10270	COG0673	inositol 2-dehydrogenase activity
DS740_RS10275	COG1082	Xylose isomerase domain protein TIM barrel
DS740_RS10280	COG1609	Transcriptional regulator
DS740_RS10300	COG0840	transmembrane signaling receptor activity
DS740_RS10300	COG5278	phosphoserine phosphatase activity
DS740_RS10305	COG2368	4-hydroxyphenylacetate
DS740_RS10310	COG4305	rare lipoprotein A
DS740_RS10315	COG3619	membrane
DS740_RS10320	COG3866	Pectate lyase
DS740_RS10325	COG2135	peptidase activity
DS740_RS10335	COG2140	Oxalate decarboxylase
DS740_RS10355	COG2720	vancomycin resistance protein
DS740_RS10370	COG3739	integral membrane protein
DS740_RS10375	COG0583	DNA-binding transcription factor activity
DS740_RS10380	COG0697	spore germination
DS740_RS10390	COG0693	protein deglycase activity
DS740_RS10395	COG2367	Beta-lactamase
DS740_RS10415	COG3848	Pyruvate phosphate dikinase
DS740_RS10415	COG0574	Belongs to the PEP-utilizing enzyme family
DS740_RS10420	COG0726	polysaccharide deacetylase
DS740_RS10430	COG2314	TM2 domain
DS740_RS10460	COG3655	Transcriptional regulator
DS740_RS10495	COG0457	Tetratricopeptide repeat
DS740_RS10505	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DS740_RS10515	COG4282	regulation of fungal-type cell wall biogenesis
DS740_RS10520	COG1231	oxidoreductase activity
DS740_RS10525	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DS740_RS10530	COG0662	Cupin 2, conserved barrel domain protein
DS740_RS10530	COG2207	Transcriptional regulator
DS740_RS10535	COG0456	acetyltransferase
DS740_RS10540	COG1309	transcriptional regulator
DS740_RS10545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DS740_RS10550	COG3708	Transcriptional regulator
DS740_RS10555	COG2378	regulation of single-species biofilm formation
DS740_RS10565	COG0640	Transcriptional regulator
DS740_RS10570	COG0741	lytic transglycosylase activity
DS740_RS10575	COG2322	membrane
DS740_RS10590	COG1619	proteins homologs of microcin C7 resistance protein MccF
DS740_RS10595	COG3239	Fatty acid desaturase
DS740_RS10600	COG4585	Histidine kinase
DS740_RS10605	COG2197	response regulator
DS740_RS10610	COG1388	LysM domain
DS740_RS10610	COG3584	3D domain protein
DS740_RS10615	COG0514	ATP-dependent DNA helicase (RecQ)
DS740_RS10630	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DS740_RS10635	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DS740_RS10650	COG0071	Belongs to the small heat shock protein (HSP20) family
DS740_RS10675	COG1012	belongs to the aldehyde dehydrogenase family
DS740_RS10680	COG1657	PFAM Prenyltransferase squalene oxidase
DS740_RS10685	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DS740_RS10690	COG0733	neurotransmitter:sodium symporter activity
DS740_RS10695	COG0385	Bile acid
DS740_RS10700	COG0508	dehydrogenase complex catalyzes the overall conversion of
DS740_RS10705	COG0567	Dehydrogenase, E1 component
DS740_RS10710	COG4548	von Willebrand factor, type A
DS740_RS10715	COG0714	Associated with various cellular activities
DS740_RS10720	COG2032	superoxide dismutase activity
DS740_RS10725	COG1388	LysM domain
DS740_RS10725	COG0791	NLP P60 protein
DS740_RS10730	COG1819	glycosyl
DS740_RS10735	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DS740_RS10740	COG0534	Mate efflux family protein
DS740_RS10745	COG1366	Belongs to the anti-sigma-factor antagonist family
DS740_RS10750	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DS740_RS10755	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DS740_RS10765	COG2962	Rard protein
DS740_RS10780	COG2610	gluconate transmembrane transporter activity
DS740_RS10785	COG1942	4-Oxalocrotonate Tautomerase
DS740_RS10790	COG1733	regulation of RNA biosynthetic process
DS740_RS10795	COG0778	Nitroreductase
DS740_RS10800	COG0400	carboxylic ester hydrolase activity
DS740_RS10805	COG0346	lactoylglutathione lyase activity
DS740_RS10815	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DS740_RS10820	COG0793	Belongs to the peptidase S41A family
DS740_RS10820	COG3409	Peptidoglycan-binding domain 1 protein
DS740_RS10825	COG2226	methyltransferase
DS740_RS10835	COG1876	peptidase activity
DS740_RS10840	COG0813	purine-nucleoside phosphorylase activity
DS740_RS10855	COG0671	phosphoesterase, PA-phosphatase related
DS740_RS10875	COG4479	Belongs to the UPF0346 family
DS740_RS10885	COG1509	lysine 2,3-aminomutase activity
DS740_RS10890	COG0456	acetyltransferase
DS740_RS10895	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DS740_RS10900	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DS740_RS10905	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DS740_RS10910	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DS740_RS10920	COG0456	acetyltransferase
DS740_RS10925	COG0463	Glycosyl transferase, family 2
DS740_RS10940	COG4641	Protein conserved in bacteria
DS740_RS10945	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
DS740_RS10950	COG1086	Polysaccharide biosynthesis protein
DS740_RS10955	COG3331	DNA recombination
DS740_RS11010	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DS740_RS11045	COG0756	dUTP diphosphatase activity
DS740_RS11050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DS740_RS11055	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DS740_RS11065	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DS740_RS11065	COG1372	Participates in initiation and elongation during chromosome replication
DS740_RS11070	COG1780	Probably involved in ribonucleotide reductase function
DS740_RS11145	COG0270	DNA (cytosine-5-)-methyltransferase activity
DS740_RS11160	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DS740_RS11185	COG3584	3D domain protein
DS740_RS11190	COG0587	DNA-directed DNA polymerase activity
DS740_RS11195	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DS740_RS11200	COG0358	DNA primase activity
DS740_RS11205	COG0305	Participates in initiation and elongation during chromosome replication
DS740_RS11215	COG2887	Belongs to the helicase family. UvrD subfamily
DS740_RS11255	COG2135	peptidase activity
DS740_RS11260	COG1793	dna ligase
DS740_RS11305	COG1388	LysM domain
DS740_RS11320	COG3645	SOS response
DS740_RS11320	COG3646	Phage regulatory protein
DS740_RS11365	COG3655	Transcriptional regulator
DS740_RS11380	COG0582	viral genome integration into host DNA
DS740_RS11465	COG3655	Transcriptional regulator
DS740_RS11535	COG0776	regulation of translation
DS740_RS11570	COG4373	Mu-like prophage FluMu protein gp28
DS740_RS11670	COG0582	viral genome integration into host DNA
DS740_RS11695	COG0741	lytic transglycosylase activity
DS740_RS11695	COG1196	nuclear chromosome segregation
DS740_RS11695	COG0739	heme binding
DS740_RS11705	COG2433	Pfam Transposase IS66
DS740_RS11715	COG4632	Exopolysaccharide biosynthesis protein
DS740_RS11715	COG5434	Belongs to the glycosyl hydrolase 28 family
DS740_RS11725	COG5632	N-Acetylmuramoyl-L-alanine amidase
DS740_RS11740	COG0457	Tetratricopeptide repeat
DS740_RS11750	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DS740_RS11775	COG5444	nuclease activity
DS740_RS11780	COG4282	regulation of fungal-type cell wall biogenesis
DS740_RS11790	COG1525	nuclease
DS740_RS11810	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DS740_RS11815	COG1086	Polysaccharide biosynthesis protein
DS740_RS11820	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DS740_RS11825	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DS740_RS11830	COG1846	Transcriptional regulator
DS740_RS11835	COG0534	Mate efflux family protein
DS740_RS11845	COG4698	Protein conserved in bacteria
DS740_RS11850	COG2755	lipolytic protein G-D-S-L family
DS740_RS11855	COG1999	signal sequence binding
DS740_RS11865	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DS740_RS11870	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DS740_RS11875	COG1272	protein, Hemolysin III
DS740_RS11880	COG0204	Acyl-transferase
DS740_RS11885	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DS740_RS11890	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DS740_RS11900	COG2136	Putative SAM-dependent methyltransferase
DS740_RS11900	COG2521	methyltransferase
DS740_RS11910	COG0129	dihydroxy-acid dehydratase activity
DS740_RS11915	COG1413	lyase activity
DS740_RS11920	COG1418	mRNA catabolic process
DS740_RS11925	COG0386	Belongs to the glutathione peroxidase family
DS740_RS11930	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
DS740_RS11935	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DS740_RS11940	COG1278	Cold shock
DS740_RS11960	COG0328	RNA-DNA hybrid ribonuclease activity
DS740_RS11965	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DS740_RS11970	COG0328	RNA-DNA hybrid ribonuclease activity
DS740_RS11980	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DS740_RS11995	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DS740_RS12005	COG1755	Isoprenylcysteine carboxyl methyltransferase
DS740_RS12010	COG3424	synthase
DS740_RS12015	COG2233	PERMEase
DS740_RS12020	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DS740_RS12025	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
DS740_RS12035	COG0800	Aldolase
DS740_RS12040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DS740_RS12045	COG1609	Transcriptional regulator
DS740_RS12050	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
DS740_RS12055	COG1028	Short-chain dehydrogenase reductase Sdr
DS740_RS12060	COG1199	ATP-dependent helicase activity
DS740_RS12075	COG0116	Belongs to the methyltransferase superfamily
DS740_RS12090	COG4474	Belongs to the UPF0398 family
DS740_RS12100	COG3359	exonuclease
DS740_RS12105	COG1111	helicase
DS740_RS12105	COG1205	dead DEAH box helicase
DS740_RS12110	COG2190	(PTS) system
DS740_RS12115	COG0071	Belongs to the small heat shock protein (HSP20) family
DS740_RS12150	COG3331	DNA recombination
DS740_RS12155	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DS740_RS12155	COG4499	WXG100 protein secretion system (Wss), protein YukC
DS740_RS12165	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DS740_RS12170	COG3935	DnaD domain protein
DS740_RS12175	COG0017	Asparaginyl-tRNA synthetase
DS740_RS12180	COG0436	Aminotransferase
DS740_RS12185	COG5353	protein conserved in bacteria
DS740_RS12195	COG1199	ATP-dependent helicase activity
DS740_RS12195	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DS740_RS12200	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DS740_RS12205	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DS740_RS12210	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DS740_RS12215	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
DS740_RS12215	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
DS740_RS12220	COG0617	tRNA 3'-terminal CCA addition
DS740_RS12225	COG0438	transferase activity, transferring glycosyl groups
DS740_RS12230	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DS740_RS12235	COG1803	Methylglyoxal synthase
DS740_RS12240	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DS740_RS12245	COG1694	Mazg nucleotide pyrophosphohydrolase
DS740_RS12250	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DS740_RS12260	COG4347	Protein of unknown function (DUF1405)
DS740_RS12265	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DS740_RS12265	COG2010	Cytochrome c
DS740_RS12270	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DS740_RS12275	COG0723	plastoquinol--plastocyanin reductase activity
DS740_RS12285	COG5582	Belongs to the UPF0302 family
DS740_RS12290	COG0457	Tetratricopeptide repeat
DS740_RS12295	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DS740_RS12300	COG0287	Prephenate dehydrogenase
DS740_RS12305	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DS740_RS12315	COG0133	tryptophan synthase activity
DS740_RS12320	COG0135	phosphoribosylanthranilate isomerase activity
DS740_RS12330	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DS740_RS12335	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DS740_RS12340	COG4401	Chorismate mutase type I
DS740_RS12345	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DS740_RS12350	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DS740_RS12355	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DS740_RS12360	COG0105	UTP biosynthetic process
DS740_RS12365	COG0142	geranyltranstransferase activity
DS740_RS12370	COG2226	methyltransferase
DS740_RS12375	COG0142	geranyltranstransferase activity
DS740_RS12385	COG0302	gtp cyclohydrolase
DS740_RS12390	COG0776	regulation of translation
DS740_RS12395	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DS740_RS12410	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DS740_RS12415	COG1160	GTP binding
DS740_RS12440	COG1304	FMN binding
DS740_RS12445	COG0539	negative regulation of cytoplasmic translation
DS740_RS12450	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DS740_RS12460	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
DS740_RS12465	COG2959	enzyme of heme biosynthesis
DS740_RS12470	COG3773	Cell wall hydrolase
DS740_RS12470	COG3409	Peptidoglycan-binding domain 1 protein
DS740_RS12475	COG2339	peptidase activity
DS740_RS12480	COG0492	ferredoxin-NADP+ reductase activity
DS740_RS12485	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DS740_RS12490	COG4862	establishment of competence for transformation
DS740_RS12495	COG1408	metallophosphoesterase
DS740_RS12505	COG1388	LysM domain
DS740_RS12510	COG1266	CAAX protease self-immunity
DS740_RS12515	COG0514	ATP-dependent DNA helicase (RecQ)
DS740_RS12520	COG4955	Helix-turn-helix domain
DS740_RS12525	COG1141	Ferredoxin
DS740_RS12530	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DS740_RS12535	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DS740_RS12540	COG0710	3-dehydroquinate dehydratase activity
DS740_RS12550	COG1595	DNA-templated transcription, initiation
DS740_RS12555	COG5002	protein histidine kinase activity
DS740_RS12560	COG0745	RESPONSE REGULATOR receiver
DS740_RS12565	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DS740_RS12570	COG1333	cytochrome c biogenesis protein
DS740_RS12575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DS740_RS12580	COG1187	pseudouridine synthase activity
DS740_RS12585	COG0700	Nucleoside recognition
DS740_RS12590	COG2715	membrane protein required for spore maturation
DS740_RS12595	COG1686	Belongs to the peptidase S11 family
DS740_RS12605	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DS740_RS12610	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DS740_RS12615	COG1547	Domain of unknown function (DUF309)
DS740_RS12620	COG0456	acetyltransferase
DS740_RS12625	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DS740_RS12630	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DS740_RS12630	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DS740_RS12635	COG0307	riboflavin synthase, alpha
DS740_RS12640	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DS740_RS12640	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DS740_RS12650	COG0681	Belongs to the peptidase S26 family
DS740_RS12665	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DS740_RS12675	COG4086	secreted protein
DS740_RS12680	COG0019	diaminopimelate decarboxylase activity
DS740_RS12685	COG0697	spore germination
DS740_RS12700	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DS740_RS12720	COG1191	sigma factor activity
DS740_RS12725	COG2172	sigma factor antagonist activity
DS740_RS12730	COG1366	Belongs to the anti-sigma-factor antagonist family
DS740_RS12735	COG1686	Belongs to the peptidase S11 family
DS740_RS12740	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DS740_RS12745	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
DS740_RS12750	COG4974	Belongs to the 'phage' integrase family
DS740_RS12760	COG0735	belongs to the Fur family
DS740_RS12765	COG1300	Membrane
DS740_RS12775	COG0281	malic enzyme
DS740_RS12780	COG1757	Na H antiporter
DS740_RS12785	COG1027	Aspartate ammonia-lyase
DS740_RS12790	COG0252	asparaginase activity
DS740_RS12795	COG1396	sequence-specific DNA binding
DS740_RS12800	COG1379	DNA repair
DS740_RS12805	COG0494	nUDIX hydrolase
DS740_RS12815	COG0667	Aldo Keto reductase
DS740_RS12825	COG1073	alpha beta
DS740_RS12835	COG4918	Iron-sulphur cluster biosynthesis
DS740_RS12840	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DS740_RS12840	COG0456	acetyltransferase
DS740_RS12845	COG2329	Antibiotic biosynthesis monooxygenase
DS740_RS12850	COG0456	acetyltransferase
DS740_RS12860	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DS740_RS12870	COG2211	Major facilitator Superfamily
DS740_RS12880	COG0346	lactoylglutathione lyase activity
DS740_RS12885	COG1072	(Pantothenic acid kinase))
DS740_RS12890	COG3048	D-serine ammonia-lyase activity
DS740_RS12895	COG0300	oxidoreductase activity
DS740_RS12900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DS740_RS12905	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DS740_RS12910	COG4187	Peptidase family M20/M25/M40
DS740_RS12915	COG1902	pentaerythritol trinitrate reductase activity
DS740_RS12920	COG0596	Alpha beta hydrolase
DS740_RS12930	COG1234	tRNA 3'-trailer cleavage
DS740_RS12935	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DS740_RS12940	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DS740_RS12945	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DS740_RS12955	COG0706	membrane insertase activity
DS740_RS12960	COG3361	conserved protein (COG2071)
DS740_RS12965	COG2195	Cleaves the N-terminal amino acid of tripeptides
DS740_RS12970	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DS740_RS12975	COG0346	lactoylglutathione lyase activity
DS740_RS12980	COG1376	ErfK ybiS ycfS ynhG family protein
DS740_RS12985	COG4129	membrane
DS740_RS12990	COG1126	abc transporter atp-binding protein
DS740_RS12995	COG0765	amino acid transport
DS740_RS13000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DS740_RS13010	COG1597	lipid kinase activity
DS740_RS13015	COG2814	Major facilitator Superfamily
DS740_RS13020	COG4978	Transcriptional regulator
DS740_RS13020	COG0789	Transcriptional regulator
DS740_RS13025	COG0508	dehydrogenase complex catalyzes the overall conversion of
DS740_RS13030	COG0022	dehydrogenase e1 component
DS740_RS13035	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DS740_RS13040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DS740_RS13045	COG3426	butyrate kinase activity
DS740_RS13050	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DS740_RS13055	COG0280	phosphate acetyltransferase
DS740_RS13060	COG3290	protein histidine kinase activity
DS740_RS13060	COG3829	transcription factor binding
DS740_RS13070	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DS740_RS13075	COG2079	MmgE PrpD family protein
DS740_RS13080	COG0372	Belongs to the citrate synthase family
DS740_RS13085	COG1960	acyl-CoA dehydrogenase activity
DS740_RS13090	COG1250	3-hydroxyacyl-CoA dehydrogenase
DS740_RS13095	COG0183	Belongs to the thiolase family
DS740_RS13100	COG0584	glycerophosphoryl diester phosphodiesterase
DS740_RS13105	COG0860	N-Acetylmuramoyl-L-alanine amidase
DS740_RS13115	COG1902	pentaerythritol trinitrate reductase activity
DS740_RS13120	COG0745	RESPONSE REGULATOR receiver
DS740_RS13125	COG0750	zinc metalloprotease
DS740_RS13130	COG0497	DNA recombination
DS740_RS13135	COG1438	arginine binding
DS740_RS13140	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DS740_RS13145	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DS740_RS13150	COG0142	geranyltranstransferase activity
DS740_RS13155	COG1722	exodeoxyribonuclease VII activity
DS740_RS13160	COG1570	exodeoxyribonuclease VII activity
DS740_RS13165	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DS740_RS13170	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DS740_RS13175	COG1302	Protein conserved in bacteria
DS740_RS13180	COG0439	Biotin carboxylase
DS740_RS13185	COG0511	ligase activity, forming carbon-carbon bonds
DS740_RS13225	COG3854	ATPases associated with a variety of cellular activities
DS740_RS13235	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DS740_RS13240	COG0006	proline dipeptidase activity
DS740_RS13245	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DS740_RS13255	COG3872	metal-dependent enzyme
DS740_RS13265	COG1752	Esterase of the alpha-beta hydrolase superfamily
DS740_RS13270	COG1321	iron dependent repressor
DS740_RS13275	COG0095	Lipoate-protein ligase
DS740_RS13280	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DS740_RS13285	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DS740_RS13290	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DS740_RS13295	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DS740_RS13300	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DS740_RS13315	COG1396	sequence-specific DNA binding
DS740_RS13325	COG0681	Belongs to the peptidase S26 family
DS740_RS13350	COG4940	Competence protein ComGF
DS740_RS13360	COG4970	Tfp pilus assembly protein FimT
DS740_RS13365	COG4537	Required for transformation and DNA binding
DS740_RS13370	COG1459	type II secretion system
DS740_RS13375	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DS740_RS13385	COG0598	Magnesium transport protein CorA
DS740_RS13390	COG1253	flavin adenine dinucleotide binding
DS740_RS13395	COG1366	Belongs to the anti-sigma-factor antagonist family
DS740_RS13405	COG1393	Belongs to the ArsC family
DS740_RS13415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DS740_RS13425	COG0011	TIGRFAM Protein of
DS740_RS13435	COG2866	Carboxypeptidase
DS740_RS13440	COG1368	sulfuric ester hydrolase activity
DS740_RS13445	COG1940	carbohydrate kinase activity
DS740_RS13450	COG4483	Protein conserved in bacteria
DS740_RS13455	COG0457	Tetratricopeptide repeat
DS740_RS13455	COG0705	Rhomboid family
DS740_RS13465	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DS740_RS13475	COG0438	transferase activity, transferring glycosyl groups
DS740_RS13490	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DS740_RS13495	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DS740_RS13500	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DS740_RS13505	COG0581	inorganic phosphate transmembrane transporter activity
DS740_RS13510	COG0573	inorganic phosphate transmembrane transporter activity
DS740_RS13515	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DS740_RS13520	COG0768	penicillin binding
DS740_RS13525	COG0477	Major facilitator Superfamily
DS740_RS13530	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DS740_RS13535	COG2839	Protein conserved in bacteria
DS740_RS13540	COG5521	maltodextrose utilization protein MalA
DS740_RS13545	COG1388	LysM domain
DS740_RS13550	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DS740_RS13555	COG4709	membrane
DS740_RS13560	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
DS740_RS13565	COG0735	belongs to the Fur family
DS740_RS13570	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DS740_RS13580	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DS740_RS13585	COG0513	Belongs to the DEAD box helicase family
DS740_RS13595	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DS740_RS13600	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DS740_RS13605	COG2384	SAM-dependent methyltransferase
DS740_RS13610	COG2010	Cytochrome c
DS740_RS13620	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DS740_RS13625	COG0358	DNA primase activity
DS740_RS13630	COG1671	Belongs to the UPF0178 family
DS740_RS13635	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DS740_RS13640	COG0517	IMP dehydrogenase activity
DS740_RS13645	COG0751	glycine-tRNA ligase activity
DS740_RS13650	COG0752	glycyl-tRNA synthetase alpha subunit
DS740_RS13655	COG1381	Involved in DNA repair and RecF pathway recombination
DS740_RS13665	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DS740_RS13670	COG0295	cytidine deaminase activity
DS740_RS13675	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DS740_RS13680	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DS740_RS13685	COG1480	7TM receptor with intracellular HD hydrolase
DS740_RS13690	COG1702	phosphate starvation-inducible protein PhoH
DS740_RS13695	COG0561	phosphatase activity
DS740_RS13710	COG4864	UPF0365 protein
DS740_RS13715	COG1030	water channel activity
DS740_RS13720	COG1610	YqeY-like protein
DS740_RS13730	COG1283	sodium-dependent phosphate transmembrane transporter activity
DS740_RS13735	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DS740_RS13740	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DS740_RS13745	COG2264	protein methyltransferase activity
DS740_RS13750	COG0484	heat shock protein binding
DS740_RS13755	COG0443	Heat shock 70 kDa protein
DS740_RS13760	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DS740_RS13765	COG1420	regulation of RNA biosynthetic process
DS740_RS13770	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DS740_RS13775	COG0481	GTPase activity
DS740_RS13785	COG0860	N-Acetylmuramoyl-L-alanine amidase
DS740_RS13790	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
DS740_RS13795	COG0268	Binds directly to 16S ribosomal RNA
DS740_RS13800	COG1466	dna polymerase III delta subunit
DS740_RS13810	COG2333	competence protein COMEC
DS740_RS13810	COG0658	competence protein
DS740_RS13815	COG2131	deaminase
DS740_RS13820	COG1596	polysaccharide export
DS740_RS13820	COG1555	photosystem II stabilization
DS740_RS13825	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DS740_RS13830	COG2226	methyltransferase
DS740_RS13835	COG0799	negative regulation of ribosome biogenesis
DS740_RS13840	COG1713	HD superfamily hydrolase involved in NAD metabolism
DS740_RS13845	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DS740_RS13850	COG1534	Rna-binding protein
DS740_RS13855	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DS740_RS13860	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DS740_RS13865	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
DS740_RS13875	COG2755	lipolytic protein G-D-S-L family
DS740_RS13880	COG3409	Peptidoglycan-binding domain 1 protein
DS740_RS13880	COG5632	N-Acetylmuramoyl-L-alanine amidase
DS740_RS13885	COG0398	Pfam SNARE associated Golgi protein
DS740_RS13900	COG3209	COG3209 Rhs family protein
DS740_RS13910	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DS740_RS13920	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DS740_RS13925	COG0798	PFAM Bile acid sodium symporter
DS740_RS13930	COG0346	lactoylglutathione lyase activity
DS740_RS13935	COG0640	Transcriptional regulator
DS740_RS13940	COG3403	YqcI/YcgG family
DS740_RS13945	COG0457	Tetratricopeptide repeat
DS740_RS13960	COG5444	nuclease activity
DS740_RS13980	COG3409	Peptidoglycan-binding domain 1 protein
DS740_RS13980	COG5632	N-Acetylmuramoyl-L-alanine amidase
DS740_RS13985	COG4824	toxin secretion phage lysis holin
DS740_RS14015	COG3778	Protein conserved in bacteria
DS740_RS14020	COG3299	homolog of phage Mu protein gp47
DS740_RS14025	COG3628	GPW Gp25 family protein
DS740_RS14035	COG4193	domain, Protein
DS740_RS14040	COG1652	LysM domain
DS740_RS14045	COG3953	SLT domain
DS740_RS14045	COG5280	Phage tail tape measure protein TP901
DS740_RS14110	COG4653	Phage capsid family
DS740_RS14115	COG0338	D12 class N6 adenine-specific DNA methyltransferase
DS740_RS14125	COG2369	cell adhesion
DS740_RS14130	COG5518	Phage portal protein
DS740_RS14135	COG1783	phage Terminase large subunit
DS740_RS14140	COG5484	DNA packaging
DS740_RS14150	COG3677	Transposase
DS740_RS14165	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
DS740_RS14175	COG1484	DNA-dependent DNA replication
DS740_RS14180	COG3935	DnaD domain protein
DS740_RS14185	COG3723	Recombinational DNA repair protein, rece pathway
DS740_RS14190	COG5377	YqaJ viral recombinase family
DS740_RS14215	COG1476	TRANSCRIPTIONal
DS740_RS14220	COG3620	sequence-specific DNA binding
DS740_RS14230	COG0563	adenylate kinase activity
DS740_RS14235	COG2856	Zn peptidase
DS740_RS14245	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DS740_RS14255	COG3223	Belongs to the PsiE family
DS740_RS14260	COG0642	Histidine kinase
DS740_RS14260	COG5002	protein histidine kinase activity
DS740_RS14265	COG0745	RESPONSE REGULATOR receiver
DS740_RS14270	COG2311	Membrane
DS740_RS14275	COG0454	-acetyltransferase
DS740_RS14280	COG2249	NAD(P)H dehydrogenase (quinone) activity
DS740_RS14290	COG0730	response to heat
DS740_RS14295	COG0425	Belongs to the sulfur carrier protein TusA family
DS740_RS14300	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DS740_RS14300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DS740_RS14310	COG0425	Belongs to the sulfur carrier protein TusA family
DS740_RS14310	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DS740_RS14320	COG2210	Belongs to the sulfur carrier protein TusA family
DS740_RS14325	COG1937	Protein conserved in bacteria
DS740_RS14340	COG0662	Cupin 2, conserved barrel domain protein
DS740_RS14355	COG0789	Transcriptional regulator
DS740_RS14355	COG4978	Transcriptional regulator
DS740_RS14360	COG2814	Major facilitator Superfamily
DS740_RS14365	COG0456	acetyltransferase
DS740_RS14370	COG1253	flavin adenine dinucleotide binding
DS740_RS14380	COG0697	spore germination
DS740_RS14385	COG0583	DNA-binding transcription factor activity
DS740_RS14390	COG2072	flavoprotein involved in K transport
DS740_RS14395	COG1230	cation diffusion facilitator family transporter
DS740_RS14400	COG1942	4-Oxalocrotonate Tautomerase
DS740_RS14405	COG0583	DNA-binding transcription factor activity
DS740_RS14415	COG1114	Component of the transport system for branched-chain amino acids
DS740_RS14420	COG1687	branched-chain amino acid
DS740_RS14425	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DS740_RS14430	COG1522	sequence-specific DNA binding
DS740_RS14435	COG2732	(Barnase) inhibitor
DS740_RS14440	COG2124	cytochrome p450
DS740_RS14450	COG1335	isochorismatase
DS740_RS14465	COG2318	DinB family
DS740_RS14475	COG2070	2-Nitropropane dioxygenase
DS740_RS14490	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DS740_RS14500	COG2186	Transcriptional regulator
DS740_RS14515	COG1028	Short-chain dehydrogenase reductase Sdr
DS740_RS14520	COG3958	Transketolase
DS740_RS14525	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DS740_RS14530	COG0477	Major facilitator Superfamily
DS740_RS14535	COG1846	Transcriptional regulator
DS740_RS14540	COG3443	Belongs to the bacterial solute-binding protein 9 family
DS740_RS14545	COG1595	DNA-templated transcription, initiation
DS740_RS14550	COG0667	Aldo Keto reductase
DS740_RS14555	COG2851	Citrate transporter
DS740_RS14560	COG0583	DNA-binding transcription factor activity
DS740_RS14565	COG2828	Protein conserved in bacteria
DS740_RS14570	COG3409	Peptidoglycan-binding domain 1 protein
DS740_RS14575	COG5566	PFAM Mor transcription activator
DS740_RS14580	COG0596	Alpha beta hydrolase
DS740_RS14585	COG4991	sh3 domain protein
DS740_RS14590	COG4991	sh3 domain protein
DS740_RS14595	COG0346	lactoylglutathione lyase activity
DS740_RS14605	COG5577	PFAM Coat F domain
DS740_RS14610	COG1063	alcohol dehydrogenase
DS740_RS14620	COG5577	PFAM Coat F domain
DS740_RS14625	COG0789	Transcriptional regulator
DS740_RS14635	COG1064	alcohol dehydrogenase
DS740_RS14640	COG0693	protein deglycase activity
DS740_RS14645	COG1621	beta-fructofuranosidase activity
DS740_RS14650	COG3716	PTS system mannose fructose sorbose family IID component
DS740_RS14655	COG3715	PTS system
DS740_RS14660	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DS740_RS14665	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
DS740_RS14670	COG3933	PFAM sigma-54 factor interaction domain-containing protein
DS740_RS14670	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DS740_RS14675	COG1113	amino acid transport
DS740_RS14680	COG1280	lysine exporter protein (LysE YggA)
DS740_RS14685	COG1378	Sugar-specific transcriptional regulator TrmB
DS740_RS14690	COG1595	DNA-templated transcription, initiation
DS740_RS14700	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DS740_RS14700	COG2755	lipolytic protein G-D-S-L family
DS740_RS14710	COG2124	cytochrome p450
DS740_RS14710	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DS740_RS14715	COG1309	transcriptional regulator
DS740_RS14720	COG2226	methyltransferase
DS740_RS14730	COG2116	formate transmembrane transporter activity
DS740_RS14735	COG5609	conserved protein (DUF2294)
DS740_RS14740	COG3383	formate dehydrogenase (NAD+) activity
DS740_RS14745	COG2427	Protein of unknown function (DUF1641)
DS740_RS14755	COG0626	cystathionine gamma-synthase activity
DS740_RS14760	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DS740_RS14765	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DS740_RS14770	COG2226	methyltransferase
DS740_RS14785	COG0768	penicillin binding
DS740_RS14790	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DS740_RS14795	COG0572	uridine kinase
DS740_RS14800	COG0826	peptidase U32
DS740_RS14805	COG0826	peptidase U32
DS740_RS14810	COG4122	O-methyltransferase activity
DS740_RS14815	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DS740_RS14820	COG3906	Belongs to the UPF0473 family
DS740_RS14825	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DS740_RS14830	COG4472	Bacterial protein of unknown function (DUF965)
DS740_RS14835	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DS740_RS14840	COG0628	permease
DS740_RS14845	COG1126	abc transporter atp-binding protein
DS740_RS14850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DS740_RS14855	COG0765	amino acid transport
DS740_RS14860	COG0765	amino acid transport
DS740_RS14875	COG3881	PFAM PRC-barrel domain
DS740_RS14880	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DS740_RS14885	COG0457	Tetratricopeptide repeat
DS740_RS14890	COG0482	sulfurtransferase activity
DS740_RS14895	COG1104	cysteine desulfurase activity
DS740_RS14900	COG1959	2 iron, 2 sulfur cluster binding
DS740_RS14905	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DS740_RS14910	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DS740_RS14920	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DS740_RS14925	COG0124	histidyl-tRNA synthetase
DS740_RS14935	COG4991	sh3 domain protein
DS740_RS14935	COG3103	Sh3 type 3 domain protein
DS740_RS14935	COG0860	N-Acetylmuramoyl-L-alanine amidase
DS740_RS14940	COG1490	D-aminoacyl-tRNA deacylase activity
DS740_RS14945	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DS740_RS14950	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DS740_RS14955	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DS740_RS14955	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DS740_RS14960	COG5416	Lipopolysaccharide assembly protein A domain
DS740_RS14965	COG0490	domain, Protein
DS740_RS14970	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DS740_RS14970	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DS740_RS14980	COG2244	polysaccharide biosynthetic process
DS740_RS14985	COG2323	membrane
DS740_RS14995	COG1862	Preprotein translocase
DS740_RS15000	COG0343	queuine tRNA-ribosyltransferase activity
DS740_RS15005	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DS740_RS15015	COG2255	four-way junction helicase activity
DS740_RS15020	COG0632	four-way junction helicase activity
DS740_RS15030	COG2814	Major facilitator Superfamily
DS740_RS15035	COG0673	inositol 2-dehydrogenase activity
DS740_RS15040	COG2112	serine threonine protein kinase
DS740_RS15055	COG1115	amino acid carrier protein
DS740_RS15060	COG0217	transcriptional regulatory protein
DS740_RS15070	COG1388	LysM domain
DS740_RS15075	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DS740_RS15080	COG0157	Belongs to the NadC ModD family
DS740_RS15085	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DS740_RS15090	COG1104	cysteine desulfurase activity
DS740_RS15095	COG1827	regulation of RNA biosynthetic process
DS740_RS15100	COG0077	Prephenate dehydratase
DS740_RS15105	COG4492	Belongs to the UPF0735 family
DS740_RS15110	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DS740_RS15115	COG3290	protein histidine kinase activity
DS740_RS15120	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DS740_RS15125	COG2868	ribosomal protein
DS740_RS15130	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DS740_RS15135	COG1994	Peptidase M50
DS740_RS15140	COG0739	heme binding
DS740_RS15145	COG2894	cell division
DS740_RS15150	COG0850	regulation of cytokinetic process
DS740_RS15155	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
DS740_RS15165	COG1077	Cell shape determining protein MreB Mrl
DS740_RS15170	COG2003	Belongs to the UPF0758 family
DS740_RS15175	COG0424	maF-like protein
DS740_RS15185	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DS740_RS15190	COG0285	dihydrofolate synthase activity
DS740_RS15195	COG0525	valine-tRNA ligase activity
DS740_RS15205	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DS740_RS15210	COG1388	LysM domain
DS740_RS15215	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DS740_RS15220	COG0113	porphobilinogen synthase activity
DS740_RS15225	COG1587	Uroporphyrinogen-III synthase
DS740_RS15230	COG0181	hydroxymethylbilane synthase activity
DS740_RS15235	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DS740_RS15240	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DS740_RS15250	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DS740_RS15255	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DS740_RS15260	COG1067	ATP-dependent peptidase activity
DS740_RS15260	COG0470	DNA polymerase III
DS740_RS15265	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DS740_RS15270	COG0544	peptidyl-prolyl cis-trans isomerase activity
DS740_RS15275	COG1477	protein flavinylation
DS740_RS15275	COG0457	Tetratricopeptide repeat
DS740_RS15280	COG0066	3-isopropylmalate dehydratase activity
DS740_RS15285	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DS740_RS15290	COG0473	3-isopropylmalate dehydrogenase activity
DS740_RS15295	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DS740_RS15300	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DS740_RS15305	COG0440	acetolactate synthase activity
DS740_RS15310	COG0028	Belongs to the TPP enzyme family
DS740_RS15320	COG0454	-acetyltransferase
DS740_RS15325	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
DS740_RS15335	COG0622	Phosphoesterase
DS740_RS15340	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DS740_RS15345	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DS740_RS15350	COG5401	PFAM Sporulation and spore germination
DS740_RS15355	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DS740_RS15360	COG1846	Transcriptional regulator
DS740_RS15365	COG2197	response regulator
DS740_RS15370	COG0824	Thioesterase
DS740_RS15375	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DS740_RS15380	COG1053	succinate dehydrogenase
DS740_RS15385	COG2009	succinate dehydrogenase
DS740_RS15390	COG1719	4-vinyl reductase, 4VR
DS740_RS15395	COG0527	aspartate kinase activity
DS740_RS15405	COG0322	excinuclease ABC activity
DS740_RS15410	COG3118	belongs to the thioredoxin family
DS740_RS15420	COG3534	alpha-L-arabinofuranosidase
DS740_RS15425	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DS740_RS15430	COG2086	electron transfer activity
DS740_RS15435	COG1024	Enoyl-CoA hydratase
DS740_RS15440	COG1309	transcriptional regulator
DS740_RS15445	COG0318	PFAM AMP-dependent synthetase and ligase
DS740_RS15450	COG3766	membrane
DS740_RS15455	COG1193	negative regulation of DNA recombination
DS740_RS15460	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DS740_RS15460	COG1796	DNA polymerase
DS740_RS15465	COG1286	toxin biosynthetic process
DS740_RS15470	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
DS740_RS15475	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DS740_RS15480	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DS740_RS15480	COG0072	phenylalanine-tRNA ligase activity
DS740_RS15485	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DS740_RS15495	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DS740_RS15505	COG3835	regulator
DS740_RS15510	COG0277	FAD linked oxidase domain protein
DS740_RS15515	COG0247	lactate metabolic process
DS740_RS15520	COG0346	lactoylglutathione lyase activity
DS740_RS15530	COG1966	Carbon starvation protein
DS740_RS15535	COG3534	alpha-L-arabinofuranosidase
DS740_RS15540	COG0395	ABC-type sugar transport system, permease component
DS740_RS15545	COG1175	transmembrane transport
DS740_RS15550	COG1653	transport
DS740_RS15555	COG0371	Dehydrogenase
DS740_RS15560	COG0647	UMP catabolic process
DS740_RS15565	COG0235	Class ii aldolase
DS740_RS15570	COG1069	ribulokinase activity
DS740_RS15575	COG2160	L-arabinose isomerase activity
DS740_RS15580	COG3507	Belongs to the glycosyl hydrolase 43 family
DS740_RS15585	COG1363	Peptidase, m42
DS740_RS15595	COG3326	Membrane
DS740_RS15600	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DS740_RS15605	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DS740_RS15610	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DS740_RS15620	COG1346	cytolysis
DS740_RS15625	COG1380	Effector of murein hydrolase LrgA
DS740_RS15630	COG3279	Response regulator of the LytR AlgR family
DS740_RS15635	COG3275	phosphorelay sensor kinase activity
DS740_RS15640	COG1011	Hydrolase
DS740_RS15645	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DS740_RS15655	COG0398	Pfam SNARE associated Golgi protein
DS740_RS15660	COG1484	DNA-dependent DNA replication
DS740_RS15665	COG3611	Membrane attachment protein
DS740_RS15670	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DS740_RS15675	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
DS740_RS15680	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DS740_RS15685	COG1733	regulation of RNA biosynthetic process
DS740_RS15690	COG2814	Major facilitator Superfamily
DS740_RS15695	COG0656	L-ascorbic acid biosynthetic process
DS740_RS15700	COG0237	dephospho-CoA kinase activity
DS740_RS15705	COG1971	Probably functions as a manganese efflux pump
DS740_RS15710	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DS740_RS15715	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DS740_RS15715	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DS740_RS15720	COG5002	protein histidine kinase activity
DS740_RS15725	COG0745	RESPONSE REGULATOR receiver
DS740_RS15730	COG0039	L-malate dehydrogenase activity
DS740_RS15735	COG0538	isocitrate dehydrogenase activity
DS740_RS15740	COG0372	Belongs to the citrate synthase family
DS740_RS15745	COG2707	UPF0756 membrane protein
DS740_RS15750	COG0628	permease
DS740_RS15755	COG3030	protein affecting phage T7 exclusion by the F plasmid
DS740_RS15760	COG0469	pyruvate kinase activity
DS740_RS15765	COG0205	6-phosphofructokinase activity
DS740_RS15770	COG0825	malonyl-CoA metabolic process
DS740_RS15775	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DS740_RS15780	COG0281	malic enzyme
DS740_RS15805	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DS740_RS15815	COG4109	DRTGG domain
DS740_RS15820	COG0730	response to heat
DS740_RS15825	COG1473	amidohydrolase
DS740_RS15830	COG0196	riboflavin kinase activity
DS740_RS15835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DS740_RS15840	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DS740_RS15845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DS740_RS15850	COG1126	abc transporter atp-binding protein
DS740_RS15855	COG0765	amino acid transport
DS740_RS15860	COG0765	amino acid transport
DS740_RS15865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DS740_RS15870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DS740_RS15875	COG0454	-acetyltransferase
DS740_RS15880	COG0583	DNA-binding transcription factor activity
DS740_RS15885	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DS740_RS15890	COG1028	Short-chain dehydrogenase reductase Sdr
DS740_RS15900	COG0165	Argininosuccinate lyase
DS740_RS15905	COG0137	argininosuccinate synthase activity
DS740_RS15910	COG0521	Mo-molybdopterin cofactor biosynthetic process
DS740_RS15915	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DS740_RS15925	COG0827	DNA restriction-modification system
DS740_RS15930	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DS740_RS15935	COG3874	Sporulation protein YtfJ
DS740_RS15945	COG1714	RDD family
DS740_RS15950	COG0616	signal peptide processing
DS740_RS15955	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DS740_RS15960	COG1574	metal-dependent hydrolase with the TIM-barrel fold
DS740_RS15965	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DS740_RS15975	COG0301	tRNA thio-modification
DS740_RS15980	COG1104	cysteine desulfurase activity
DS740_RS15985	COG1114	Component of the transport system for branched-chain amino acids
DS740_RS15990	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DS740_RS15995	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DS740_RS16000	COG1309	transcriptional regulator
DS740_RS16005	COG1956	GAF domain-containing protein
DS740_RS16010	COG2203	Gaf domain
DS740_RS16010	COG2199	diguanylate cyclase activity
DS740_RS16020	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DS740_RS16025	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DS740_RS16035	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DS740_RS16040	COG0454	-acetyltransferase
DS740_RS16045	COG0517	IMP dehydrogenase activity
DS740_RS16050	COG0123	including yeast histone deacetylase and acetoin utilization protein
DS740_RS16055	COG1360	Flagellar Motor Protein
DS740_RS16060	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DS740_RS16065	COG1609	Transcriptional regulator
DS740_RS16070	COG1605	Chorismate mutase
DS740_RS16070	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DS740_RS16075	COG3118	belongs to the thioredoxin family
DS740_RS16080	COG4980	gas vesicle protein
DS740_RS16085	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
DS740_RS16090	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DS740_RS16095	COG1674	ftsk spoiiie
DS740_RS16100	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DS740_RS16105	COG4848	Belongs to the UPF0354 family
DS740_RS16110	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DS740_RS16120	COG1363	Peptidase, m42
DS740_RS16125	COG5584	Small secreted protein
DS740_RS16130	COG0281	malic enzyme
DS740_RS16135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DS740_RS16140	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DS740_RS16150	COG0510	thiamine kinase activity
DS740_RS16155	COG1523	belongs to the glycosyl hydrolase 13 family
DS740_RS16160	COG1597	lipid kinase activity
DS740_RS16170	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
DS740_RS16175	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DS740_RS16180	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DS740_RS16185	COG2252	PERMEase
DS740_RS16190	COG4473	ABC transporter
DS740_RS16195	COG1131	(ABC) transporter
DS740_RS16200	COG1349	DNA-binding transcription factor activity
DS740_RS16205	COG1187	pseudouridine synthase activity
DS740_RS16210	COG2244	polysaccharide biosynthetic process
DS740_RS16215	COG2081	HI0933 family
DS740_RS16220	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DS740_RS16230	COG5578	integral membrane protein
DS740_RS16235	COG0673	inositol 2-dehydrogenase activity
DS740_RS16240	COG1653	transport
DS740_RS16245	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DS740_RS16250	COG4209	transmembrane transport
DS740_RS16255	COG2207	Transcriptional regulator
DS740_RS16260	COG1653	transport
DS740_RS16265	COG0395	ABC-type sugar transport system, permease component
DS740_RS16270	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DS740_RS16275	COG2124	cytochrome p450
DS740_RS16280	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DS740_RS16290	COG0156	8-amino-7-oxononanoate synthase activity
DS740_RS16295	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DS740_RS16305	COG1073	alpha beta
DS740_RS16310	COG1609	Transcriptional regulator
DS740_RS16315	COG1653	transport
DS740_RS16320	COG1175	transmembrane transport
DS740_RS16325	COG0395	ABC-type sugar transport system, permease component
DS740_RS16330	COG1486	melibiose metabolic process
DS740_RS16335	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DS740_RS16340	COG0495	leucyl-tRNA aminoacylation
DS740_RS16350	COG1366	Belongs to the anti-sigma-factor antagonist family
DS740_RS16350	COG2202	Pas domain
DS740_RS16355	COG2814	Major facilitator Superfamily
DS740_RS16360	COG2433	Pfam Transposase IS66
DS740_RS16365	COG0577	efflux transmembrane transporter activity
DS740_RS16370	COG1136	(ABC) transporter
DS740_RS16375	COG2205	protein histidine kinase activity
DS740_RS16380	COG0745	RESPONSE REGULATOR receiver
DS740_RS16385	COG0577	efflux transmembrane transporter activity
DS740_RS16390	COG1136	(ABC) transporter
DS740_RS16405	COG1131	(ABC) transporter
DS740_RS16410	COG1725	Transcriptional regulator
DS740_RS16420	COG1242	4 iron, 4 sulfur cluster binding
DS740_RS16425	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DS740_RS16435	COG2267	carboxylic ester hydrolase activity
DS740_RS16440	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DS740_RS16445	COG1113	amino acid transport
DS740_RS16450	COG0367	asparagine synthase
DS740_RS16455	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DS740_RS16460	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
DS740_RS16470	COG1506	peptidase
DS740_RS16475	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DS740_RS16480	COG1116	anion transmembrane transporter activity
DS740_RS16485	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DS740_RS16490	COG0494	nUDIX hydrolase
DS740_RS16495	COG4824	toxin secretion phage lysis holin
DS740_RS16500	COG0783	Belongs to the Dps family
DS740_RS16515	COG1854	S-ribosylhomocysteine lyase activity
DS740_RS16520	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DS740_RS16525	COG0288	reversible hydration of carbon dioxide
DS740_RS16530	COG0254	rRNA binding
DS740_RS16535	COG1271	oxidase subunit
DS740_RS16540	COG1294	oxidase, subunit
DS740_RS16550	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DS740_RS16555	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DS740_RS16555	COG1321	iron dependent repressor
DS740_RS16560	COG1121	(ABC) transporter
DS740_RS16565	COG0803	Belongs to the bacterial solute-binding protein 9 family
DS740_RS16570	COG4948	Mandelate Racemase Muconate Lactonizing
DS740_RS16575	COG0318	PFAM AMP-dependent synthetase and ligase
DS740_RS16580	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DS740_RS16585	COG0596	Alpha beta hydrolase
DS740_RS16590	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
DS740_RS16595	COG1169	isochorismate synthase
DS740_RS16605	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DS740_RS16610	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DS740_RS16615	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DS740_RS16620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DS740_RS16625	COG0438	transferase activity, transferring glycosyl groups
DS740_RS16635	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DS740_RS16640	COG0438	transferase activity, transferring glycosyl groups
DS740_RS16645	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DS740_RS16650	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
DS740_RS16655	COG0058	SHG alpha-glucan phosphorylase activity
DS740_RS16660	COG0297	glycogen (starch) synthase activity
DS740_RS16665	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DS740_RS16670	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DS740_RS16675	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DS740_RS16800	COG3859	Proton-coupled thiamine transporter YuaJ
DS740_RS16805	COG1247	-acetyltransferase
DS740_RS16810	COG2268	Band 7 protein
DS740_RS16815	COG1585	Membrane protein implicated in regulation of membrane protease activity
DS740_RS16820	COG2318	DinB family
DS740_RS16830	COG1454	alcohol dehydrogenase
DS740_RS16835	COG1012	belongs to the aldehyde dehydrogenase family
DS740_RS16840	COG1510	regulation of RNA biosynthetic process
DS740_RS16850	COG0569	domain protein
DS740_RS16855	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DS740_RS16860	COG4682	membrane
DS740_RS16865	COG1705	Flagellar rod assembly protein muramidase FlgJ
DS740_RS16870	COG0477	Major facilitator Superfamily
DS740_RS16875	COG5553	Cysteine dioxygenase type I
DS740_RS16885	COG1968	undecaprenyl-diphosphatase activity
DS740_RS16890	COG0628	permease
DS740_RS16895	COG0673	inositol 2-dehydrogenase activity
DS740_RS16900	COG4806	L-rhamnose isomerase
DS740_RS16905	COG3254	rhamnose metabolic process
DS740_RS16910	COG1070	Carbohydrate kinase
DS740_RS16915	COG1349	DNA-binding transcription factor activity
DS740_RS16920	COG3347	Dehydrogenase
DS740_RS16920	COG1028	Short-chain dehydrogenase reductase Sdr
DS740_RS16930	COG0840	transmembrane signaling receptor activity
DS740_RS16935	COG0840	transmembrane signaling receptor activity
DS740_RS16940	COG0840	transmembrane signaling receptor activity
DS740_RS16945	COG0840	transmembrane signaling receptor activity
DS740_RS16960	COG0432	Pfam Uncharacterised protein family UPF0047
DS740_RS16965	COG0366	Alpha amylase catalytic
DS740_RS16970	COG1253	flavin adenine dinucleotide binding
DS740_RS16975	COG2738	Putative neutral zinc metallopeptidase
DS740_RS16990	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DS740_RS17005	COG0166	Belongs to the GPI family
DS740_RS17010	COG1979	alcohol dehydrogenase
DS740_RS17015	COG1979	alcohol dehydrogenase
DS740_RS17020	COG2155	Conserved Protein
DS740_RS17025	COG1098	S1 RNA binding domain
DS740_RS17030	COG0436	Aminotransferase
DS740_RS17035	COG1522	sequence-specific DNA binding
DS740_RS17040	COG2267	carboxylic ester hydrolase activity
DS740_RS17050	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DS740_RS17055	COG2205	protein histidine kinase activity
DS740_RS17065	COG5018	Exonuclease
DS740_RS17075	COG2814	Major facilitator Superfamily
DS740_RS17080	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DS740_RS17085	COG3011	Protein conserved in bacteria
DS740_RS17095	COG3290	protein histidine kinase activity
DS740_RS17100	COG4565	transcriptional regulatory protein
DS740_RS17105	COG1744	ABC transporter substrate-binding protein PnrA-like
DS740_RS17110	COG3845	ABC transporter
DS740_RS17115	COG4603	Belongs to the binding-protein-dependent transport system permease family
DS740_RS17120	COG1079	Belongs to the binding-protein-dependent transport system permease family
DS740_RS17125	COG3493	citrate carrier protein
DS740_RS17135	COG2111	Na H antiporter
DS740_RS17135	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DS740_RS17140	COG2111	Na H antiporter
DS740_RS17145	COG1006	Multisubunit Na H antiporter MnhC subunit
DS740_RS17150	COG0651	ATP synthesis coupled electron transport
DS740_RS17155	COG1863	multisubunit Na H antiporter MnhE subunit
DS740_RS17160	COG2212	antiporter activity
DS740_RS17165	COG1320	monovalent cation:proton antiporter activity
DS740_RS17170	COG2050	protein possibly involved in aromatic compounds catabolism
DS740_RS17175	COG2197	response regulator
DS740_RS17180	COG4585	Histidine kinase
DS740_RS17190	COG0142	geranyltranstransferase activity
DS740_RS17205	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
DS740_RS17210	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DS740_RS17215	COG1335	isochorismatase
DS740_RS17220	COG5506	Protein of unknown function (DUF1694)
DS740_RS17235	COG0628	permease
DS740_RS17250	COG1418	mRNA catabolic process
DS740_RS17255	COG1028	Short-chain dehydrogenase reductase Sdr
DS740_RS17265	COG1511	domain protein
DS740_RS17270	COG0433	COG0433 Predicted ATPase
DS740_RS17270	COG1674	ftsk spoiiie
DS740_RS17275	COG4499	WXG100 protein secretion system (Wss), protein YukC
DS740_RS17280	COG5417	Belongs to the EsaB family
DS740_RS17285	COG4842	Belongs to the WXG100 family
DS740_RS17290	COG2508	Transcriptional regulator
DS740_RS17290	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DS740_RS17295	COG0686	Belongs to the AlaDH PNT family
DS740_RS17300	COG5634	Uncharacterized conserved protein (DUF2278)
DS740_RS17305	COG3251	PFAM MbtH domain protein
DS740_RS17310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DS740_RS17315	COG1535	isochorismatase
DS740_RS17315	COG3433	isochorismatase activity
DS740_RS17320	COG1021	2,3-dihydroxybenzoate-AMP ligase
DS740_RS17325	COG1169	isochorismate synthase
DS740_RS17330	COG1028	Short-chain dehydrogenase reductase Sdr
DS740_RS17335	COG2819	hydrolase of the alpha beta superfamily
DS740_RS17340	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DS740_RS17345	COG1268	BioY protein
DS740_RS17350	COG2056	Na+-H+ antiporter family
DS740_RS17355	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DS740_RS17360	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
DS740_RS17365	COG3584	3D domain protein
DS740_RS17380	COG1252	NADH dehydrogenase
DS740_RS17385	COG0492	ferredoxin-NADP+ reductase activity
DS740_RS17395	COG0516	GMP reductase activity
DS740_RS17400	COG2808	Putative FMN-binding domain
DS740_RS17405	COG0456	acetyltransferase
DS740_RS17410	COG0316	Belongs to the HesB IscA family
DS740_RS17415	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DS740_RS17420	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DS740_RS17425	COG4844	belongs to the
DS740_RS17430	COG1252	NADH dehydrogenase
DS740_RS17435	COG4837	Protein of unknown function (DUF1462)
DS740_RS17440	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DS740_RS17445	COG0823	Involved in the tonB-independent uptake of proteins
DS740_RS17445	COG4946	Tricorn protease homolog
DS740_RS17445	COG1506	peptidase
DS740_RS17450	COG0083	homoserine kinase activity
DS740_RS17455	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DS740_RS17460	COG0460	homoserine dehydrogenase
DS740_RS17465	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DS740_RS17470	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DS740_RS17475	COG0647	UMP catabolic process
DS740_RS17480	COG2445	Protein of unknown function DUF86
DS740_RS17485	COG4470	Protein conserved in bacteria
DS740_RS17495	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DS740_RS17500	COG0739	heme binding
DS740_RS17510	COG3377	Domain of unknown function (DUF1805)
DS740_RS17515	COG0737	Belongs to the 5'-nucleotidase family
DS740_RS17520	COG0730	response to heat
DS740_RS17525	COG1801	Protein of unknown function DUF72
DS740_RS17535	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DS740_RS17540	COG2508	Transcriptional regulator
DS740_RS17545	COG2233	PERMEase
DS740_RS17550	COG2233	PERMEase
DS740_RS17555	COG3195	allantoin biosynthetic process
DS740_RS17555	COG3648	Uricase
DS740_RS17560	COG2351	hydroxyisourate hydrolase activity
DS740_RS17570	COG2080	2 iron, 2 sulfur cluster binding
DS740_RS17575	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DS740_RS17580	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
DS740_RS17585	COG2068	MobA-Related Protein
DS740_RS17590	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DS740_RS17595	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DS740_RS17600	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DS740_RS17605	COG2356	endonuclease I
DS740_RS17610	COG3842	ATPase activity
DS740_RS17615	COG2188	Transcriptional regulator
DS740_RS17620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DS740_RS17625	COG0395	ABC-type sugar transport system, permease component
DS740_RS17630	COG1175	transmembrane transport
DS740_RS17635	COG1653	transport
DS740_RS17640	COG2222	sugar isomerase
DS740_RS17645	COG0322	excinuclease ABC activity
DS740_RS17650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DS740_RS17665	COG0346	lactoylglutathione lyase activity
DS740_RS17670	COG0640	Transcriptional regulator
DS740_RS17675	COG0719	Fe-S assembly protein
DS740_RS17680	COG0822	iron-sulfur transferase activity
DS740_RS17685	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DS740_RS17690	COG0719	Fe-S assembly protein
DS740_RS17695	COG0396	ATPase activity
DS740_RS17710	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DS740_RS17715	COG1464	Belongs to the NlpA lipoprotein family
DS740_RS17720	COG2011	ABC-type metal ion transport system permease component
DS740_RS17725	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DS740_RS17735	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DS740_RS17740	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DS740_RS17750	COG0509	glycine decarboxylation via glycine cleavage system
DS740_RS17755	COG1393	Belongs to the ArsC family
DS740_RS17760	COG1960	acyl-CoA dehydrogenase activity
DS740_RS17765	COG0183	Belongs to the thiolase family
DS740_RS17770	COG1024	Enoyl-CoA hydratase
DS740_RS17770	COG1250	3-hydroxyacyl-CoA dehydrogenase
DS740_RS17780	COG0506	proline dehydrogenase activity
DS740_RS17790	COG5577	PFAM Coat F domain
DS740_RS17795	COG1846	Transcriptional regulator
DS740_RS17800	COG0477	Major facilitator Superfamily
DS740_RS17805	COG1942	4-Oxalocrotonate Tautomerase
DS740_RS17815	COG0583	DNA-binding transcription factor activity
DS740_RS17825	COG1120	ATPase activity
DS740_RS17840	COG1028	Short-chain dehydrogenase reductase Sdr
DS740_RS17845	COG0783	Belongs to the Dps family
DS740_RS17850	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DS740_RS17855	COG0745	RESPONSE REGULATOR receiver
DS740_RS17860	COG2770	Histidine kinase
DS740_RS17860	COG2205	protein histidine kinase activity
DS740_RS17870	COG1309	transcriptional regulator
DS740_RS17875	COG0114	fumarate hydratase activity
DS740_RS17885	COG0697	spore germination
DS740_RS17890	COG0814	amino acid
DS740_RS17900	COG2197	response regulator
DS740_RS17905	COG4585	Histidine kinase
DS740_RS17910	COG4758	membrane
DS740_RS17915	COG3595	metallopeptidase activity
DS740_RS17920	COG1842	Phage shock protein A
DS740_RS17925	COG4758	membrane
DS740_RS17930	COG2814	Major facilitator Superfamily
DS740_RS17935	COG2096	Adenosyltransferase
DS740_RS17940	COG1120	ATPase activity
DS740_RS17945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DS740_RS17950	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DS740_RS17955	COG1028	Short-chain dehydrogenase reductase Sdr
DS740_RS17960	COG3386	PFAM SMP-30 Gluconolaconase
DS740_RS17965	COG2205	protein histidine kinase activity
DS740_RS17970	COG0745	RESPONSE REGULATOR receiver
DS740_RS17980	COG1191	sigma factor activity
DS740_RS17990	COG2140	Oxalate decarboxylase
DS740_RS18000	COG0577	efflux transmembrane transporter activity
DS740_RS18005	COG1136	(ABC) transporter
DS740_RS18010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DS740_RS18015	COG1120	ATPase activity
DS740_RS18020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DS740_RS18025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DS740_RS18030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DS740_RS18040	COG0531	amino acid
DS740_RS18055	COG1988	membrane-bound metal-dependent
DS740_RS18060	COG1368	sulfuric ester hydrolase activity
DS740_RS18065	COG1910	domain protein
DS740_RS18070	COG0725	ABC transporter, periplasmic molybdate-binding protein
DS740_RS18075	COG4149	molybdate abc transporter
DS740_RS18080	COG0656	L-ascorbic acid biosynthetic process
DS740_RS18090	COG0025	NhaP-type Na H and K H
DS740_RS18095	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DS740_RS18100	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DS740_RS18105	COG3973	AAA domain
DS740_RS18115	COG2860	membrane
DS740_RS18120	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
DS740_RS18125	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DS740_RS18130	COG2217	Heavy metal translocating P-type atpase
DS740_RS18135	COG2217	Heavy metal translocating P-type atpase
DS740_RS18140	COG2608	mercury ion transmembrane transporter activity
DS740_RS18145	COG1937	Protein conserved in bacteria
DS740_RS18150	COG0673	inositol 2-dehydrogenase activity
DS740_RS18155	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DS740_RS18160	COG1289	transmembrane transporter activity
DS740_RS18170	COG2076	Multidrug Resistance protein
DS740_RS18175	COG1309	transcriptional regulator
DS740_RS18180	COG1028	Short-chain dehydrogenase reductase Sdr
DS740_RS18205	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DS740_RS18210	COG0557	exoribonuclease II activity
DS740_RS18215	COG1647	Serine aminopeptidase, S33
DS740_RS18220	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DS740_RS18225	COG0596	Alpha beta hydrolase
DS740_RS18230	COG1476	TRANSCRIPTIONal
DS740_RS18235	COG1396	sequence-specific DNA binding
DS740_RS18240	COG1396	sequence-specific DNA binding
DS740_RS18245	COG1733	regulation of RNA biosynthetic process
DS740_RS18250	COG0840	transmembrane signaling receptor activity
DS740_RS18275	COG1131	(ABC) transporter
DS740_RS18305	COG1174	glycine betaine transport
DS740_RS18310	COG1732	Glycine betaine
DS740_RS18315	COG1174	glycine betaine transport
DS740_RS18320	COG1125	glycine betaine transport
DS740_RS18320	COG0517	IMP dehydrogenase activity
DS740_RS18325	COG1510	regulation of RNA biosynthetic process
DS740_RS18330	COG1174	glycine betaine transport
DS740_RS18335	COG1732	Glycine betaine
DS740_RS18340	COG1174	glycine betaine transport
DS740_RS18345	COG0517	IMP dehydrogenase activity
DS740_RS18345	COG1125	glycine betaine transport
DS740_RS18350	COG1510	regulation of RNA biosynthetic process
DS740_RS18355	COG2095	MarC family integral membrane protein
DS740_RS18365	COG3064	Membrane
DS740_RS18370	COG4640	response to antibiotic
DS740_RS18375	COG0456	acetyltransferase
DS740_RS18380	COG0148	phosphopyruvate hydratase activity
DS740_RS18385	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DS740_RS18390	COG0149	triose-phosphate isomerase activity
DS740_RS18395	COG0126	phosphoglycerate kinase activity
DS740_RS18400	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DS740_RS18405	COG2390	Transcriptional regulator
DS740_RS18410	COG2814	Major facilitator Superfamily
DS740_RS18415	COG1609	Transcriptional regulator
DS740_RS18420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DS740_RS18430	COG0583	DNA-binding transcription factor activity
DS740_RS18435	COG0697	spore germination
DS740_RS18440	COG1113	amino acid transport
DS740_RS18445	COG3858	chitin binding
DS740_RS18450	COG1556	Lactate utilization protein
DS740_RS18455	COG1139	Iron-sulfur cluster binding protein
DS740_RS18460	COG0247	lactate metabolic process
DS740_RS18465	COG2197	response regulator
DS740_RS18470	COG4585	Histidine kinase
DS740_RS18475	COG0842	Transport permease protein
DS740_RS18480	COG1131	(ABC) transporter
DS740_RS18485	COG0596	Alpha beta hydrolase
DS740_RS18490	COG2208	phosphoserine phosphatase activity
DS740_RS18495	COG3867	Arabinogalactan endo-beta-1,4-galactanase
DS740_RS18500	COG1874	Beta-galactosidase
DS740_RS18505	COG3833	ABC-type maltose transport systems, permease component
DS740_RS18510	COG1175	transmembrane transport
DS740_RS18515	COG2182	Extracellular solute-binding protein
DS740_RS18520	COG1609	Transcriptional regulator
DS740_RS18525	COG2186	Transcriptional regulator
DS740_RS18530	COG1620	l-lactate permease
DS740_RS18535	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DS740_RS18545	COG5039	Polysaccharide pyruvyl transferase
DS740_RS18550	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DS740_RS18555	COG0110	maltose O-acetyltransferase activity
DS740_RS18560	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DS740_RS18565	COG2244	polysaccharide biosynthetic process
DS740_RS18570	COG1216	Glycosyl transferase, family 2
DS740_RS18575	COG5039	Polysaccharide pyruvyl transferase
DS740_RS18580	COG1216	Glycosyl transferase, family 2
DS740_RS18590	COG0438	transferase activity, transferring glycosyl groups
DS740_RS18595	COG1215	transferase activity, transferring glycosyl groups
DS740_RS18600	COG0438	transferase activity, transferring glycosyl groups
DS740_RS18605	COG1086	Polysaccharide biosynthesis protein
DS740_RS18610	COG0489	protein tyrosine kinase activity
DS740_RS18615	COG3944	biosynthesis protein
DS740_RS18620	COG1396	sequence-specific DNA binding
DS740_RS18625	COG2272	Belongs to the type-B carboxylesterase lipase family
DS740_RS18635	COG3479	Phenolic acid decarboxylase
DS740_RS18645	COG1794	racemase activity, acting on amino acids and derivatives
DS740_RS18650	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DS740_RS18655	COG1621	beta-fructofuranosidase activity
DS740_RS18660	COG1621	beta-fructofuranosidase activity
DS740_RS18665	COG0531	amino acid
DS740_RS18670	COG1309	transcriptional regulator
DS740_RS18675	COG2076	Multidrug Resistance protein
DS740_RS18680	COG2076	Multidrug Resistance protein
DS740_RS18695	COG0740	serine-type endopeptidase activity
DS740_RS18700	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DS740_RS18705	COG0366	Alpha amylase catalytic
DS740_RS18710	COG1554	hydrolase, family 65, central catalytic
DS740_RS18715	COG5521	maltodextrose utilization protein MalA
DS740_RS18720	COG3833	ABC-type maltose transport systems, permease component
DS740_RS18725	COG1175	transmembrane transport
DS740_RS18730	COG2182	Extracellular solute-binding protein
DS740_RS18740	COG1609	Transcriptional regulator
DS740_RS18745	COG1611	Belongs to the LOG family
DS740_RS18750	COG1694	Mazg nucleotide pyrophosphohydrolase
DS740_RS18755	COG0659	secondary active sulfate transmembrane transporter activity
DS740_RS18760	COG0288	reversible hydration of carbon dioxide
DS740_RS18765	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DS740_RS18770	COG0577	efflux transmembrane transporter activity
DS740_RS18775	COG1136	(ABC) transporter
DS740_RS18780	COG5002	protein histidine kinase activity
DS740_RS18785	COG0745	RESPONSE REGULATOR receiver
DS740_RS18800	COG2162	N-hydroxyarylamine O-acetyltransferase activity
DS740_RS18805	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DS740_RS18810	COG1481	regulation of sporulation
DS740_RS18815	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DS740_RS18820	COG1660	Displays ATPase and GTPase activities
DS740_RS18825	COG1051	belongs to the nudix hydrolase family
DS740_RS18830	COG0492	ferredoxin-NADP+ reductase activity
DS740_RS18835	COG0791	NLP P60 protein
DS740_RS18835	COG3883	PFAM NLP P60 protein
DS740_RS18840	COG0457	Tetratricopeptide repeat
DS740_RS18845	COG1132	(ABC) transporter
DS740_RS18865	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DS740_RS18865	COG0140	phosphoribosyl-ATP diphosphatase activity
DS740_RS18870	COG0107	imidazoleglycerol-phosphate synthase activity
DS740_RS18875	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DS740_RS18880	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DS740_RS18885	COG0131	Imidazoleglycerol-phosphate dehydratase
DS740_RS18890	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DS740_RS18895	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DS740_RS18900	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DS740_RS18905	COG4990	cell redox homeostasis
DS740_RS18910	COG5297	Belongs to the glycosyl hydrolase family 6
DS740_RS18915	COG0110	maltose O-acetyltransferase activity
DS740_RS18920	COG0546	phosphoglycolate phosphatase activity
DS740_RS18925	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DS740_RS18930	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DS740_RS18935	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DS740_RS18940	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DS740_RS18945	COG0363	glucosamine-6-phosphate deaminase activity
DS740_RS18950	COG2188	Transcriptional regulator
DS740_RS18955	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DS740_RS18960	COG1846	Transcriptional regulator
DS740_RS18975	COG1846	Transcriptional regulator
DS740_RS18980	COG2814	Major facilitator Superfamily
DS740_RS18985	COG1950	PFAM Membrane protein of
DS740_RS18990	COG1983	PspC domain protein
DS740_RS18995	COG3595	metallopeptidase activity
DS740_RS19015	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DS740_RS19020	COG0556	nucleotide-excision repair
DS740_RS19025	COG4897	Protein conserved in bacteria
DS740_RS19030	COG0574	Belongs to the PEP-utilizing enzyme family
DS740_RS19030	COG3848	Pyruvate phosphate dikinase
DS740_RS19035	COG1309	transcriptional regulator
DS740_RS19040	COG2814	Major facilitator Superfamily
DS740_RS19045	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DS740_RS19055	COG3409	Peptidoglycan-binding domain 1 protein
DS740_RS19055	COG0793	Belongs to the peptidase S41A family
DS740_RS19060	COG2177	Part of the ABC transporter FtsEX involved in
DS740_RS19065	COG2884	Cell division ATP-binding protein ftsE
DS740_RS19070	COG2010	Cytochrome c
DS740_RS19075	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DS740_RS19085	COG0653	protein targeting
DS740_RS19090	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DS740_RS19105	COG1516	flagellar protein fliS
DS740_RS19110	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
DS740_RS19115	COG1334	flagellar protein FlaG
DS740_RS19120	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DS740_RS19125	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
DS740_RS19130	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
DS740_RS19140	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DS740_RS19145	COG1256	bacterial-type flagellum assembly
DS740_RS19145	COG4786	Flagellar basal body rod
DS740_RS19150	COG3418	PFAM FlgN family protein
DS740_RS19155	COG2747	anti-sigma28 factor FlgM
DS740_RS19165	COG1040	competence protein
DS740_RS19175	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DS740_RS19180	COG1307	EDD domain protein, DegV family
DS740_RS19185	COG2197	response regulator
DS740_RS19190	COG4585	Histidine kinase
DS740_RS19195	COG1739	Uncharacterized protein family UPF0029
DS740_RS19200	COG1316	TRANSCRIPTIONal
DS740_RS19205	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DS740_RS19210	COG0438	transferase activity, transferring glycosyl groups
DS740_RS19215	COG1215	transferase activity, transferring glycosyl groups
DS740_RS19220	COG3206	protein involved in exopolysaccharide biosynthesis
DS740_RS19225	COG3307	-O-antigen
DS740_RS19230	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DS740_RS19235	COG0297	glycogen (starch) synthase activity
DS740_RS19235	COG0438	transferase activity, transferring glycosyl groups
DS740_RS19240	COG2244	polysaccharide biosynthetic process
DS740_RS19255	COG0860	N-Acetylmuramoyl-L-alanine amidase
DS740_RS19255	COG2247	cell wall binding repeat
DS740_RS19260	COG2247	cell wall binding repeat
DS740_RS19260	COG2385	sporulation resulting in formation of a cellular spore
DS740_RS19270	COG1316	TRANSCRIPTIONal
DS740_RS19275	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DS740_RS19295	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DS740_RS19300	COG1134	teichoic acid transport
DS740_RS19305	COG1682	transport, permease protein
DS740_RS19310	COG1215	transferase activity, transferring glycosyl groups
DS740_RS19310	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DS740_RS19315	COG0463	Glycosyl transferase, family 2
DS740_RS19360	COG4193	domain, Protein
DS740_RS19365	COG1482	cell wall glycoprotein biosynthetic process
DS740_RS19370	COG0697	spore germination
DS740_RS19375	COG0814	amino acid
DS740_RS19385	COG2814	Major facilitator Superfamily
DS740_RS19390	COG1316	TRANSCRIPTIONal
DS740_RS19395	COG0561	phosphatase activity
DS740_RS19400	COG0791	NLP P60 protein
DS740_RS19410	COG2843	Capsule synthesis protein
DS740_RS19420	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DS740_RS19425	COG1609	Transcriptional regulator
DS740_RS19430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DS740_RS19435	COG1869	D-ribose catabolic process
DS740_RS19440	COG1129	ABC transporter
DS740_RS19445	COG1172	Belongs to the binding-protein-dependent transport system permease family
DS740_RS19450	COG1879	ABC-type sugar transport system periplasmic component
DS740_RS19455	COG3103	Sh3 type 3 domain protein
DS740_RS19465	COG2249	NAD(P)H dehydrogenase (quinone) activity
DS740_RS19470	COG3527	Alpha-acetolactate decarboxylase
DS740_RS19475	COG0028	Belongs to the TPP enzyme family
DS740_RS19480	COG0583	DNA-binding transcription factor activity
DS740_RS19485	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DS740_RS19500	COG5337	Spore coat protein CotH
DS740_RS19510	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DS740_RS19520	COG0405	Gamma-glutamyltransferase
DS740_RS19525	COG1522	sequence-specific DNA binding
DS740_RS19530	COG2059	Chromate
DS740_RS19535	COG2059	Chromate
DS740_RS19550	COG5444	nuclease activity
DS740_RS19570	COG3878	Protein conserved in bacteria
DS740_RS19575	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DS740_RS19580	COG4464	protein tyrosine phosphatase activity
DS740_RS19585	COG0489	protein tyrosine kinase activity
DS740_RS19590	COG3944	biosynthesis protein
DS740_RS19600	COG4715	Zinc finger, swim domain protein
DS740_RS19605	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DS740_RS19620	COG1349	DNA-binding transcription factor activity
DS740_RS19625	COG0629	single-stranded DNA binding
DS740_RS19640	COG3764	Sortase (surface protein transpeptidase)
DS740_RS19650	COG3279	Response regulator of the LytR AlgR family
DS740_RS19655	COG0745	RESPONSE REGULATOR receiver
DS740_RS19655	COG2972	Histidine kinase
DS740_RS19660	COG1970	mechanosensitive ion channel activity
DS740_RS19665	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DS740_RS19670	COG0457	Tetratricopeptide repeat
DS740_RS19675	COG4786	Flagellar basal body rod
DS740_RS19680	COG4786	Flagellar basal body rod
DS740_RS19685	COG1077	Cell shape determining protein MreB Mrl
DS740_RS19690	COG1609	Transcriptional regulator
DS740_RS19700	COG1846	Transcriptional regulator
DS740_RS19705	COG2814	Major facilitator Superfamily
DS740_RS19710	COG3420	alginic acid biosynthetic process
DS740_RS19715	COG1953	Uracil, thiamine, allantoin
DS740_RS19720	COG0477	Major facilitator Superfamily
DS740_RS19725	COG1335	isochorismatase
DS740_RS19735	COG0004	ammonium transporteR
DS740_RS19740	COG0347	Belongs to the P(II) protein family
DS740_RS19745	COG0671	phosphoesterase, PA-phosphatase related
DS740_RS19755	COG0739	heme binding
DS740_RS19760	COG1247	-acetyltransferase
DS740_RS19775	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DS740_RS19780	COG0789	Transcriptional regulator
DS740_RS19790	COG2910	NAD(P)H-binding
DS740_RS19795	COG1959	2 iron, 2 sulfur cluster binding
DS740_RS19800	COG0804	urea catabolic process
DS740_RS19805	COG0832	Belongs to the urease beta subunit family
DS740_RS19810	COG0831	urea catabolic process
DS740_RS19825	COG3237	CsbD-like
DS740_RS19830	COG1994	Peptidase M50
DS740_RS19835	COG0457	Tetratricopeptide repeat
DS740_RS19845	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DS740_RS19850	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DS740_RS19860	COG2304	oxidoreductase activity
DS740_RS19870	COG2304	oxidoreductase activity
DS740_RS19875	COG2385	sporulation resulting in formation of a cellular spore
DS740_RS19880	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DS740_RS19890	COG4836	Membrane
DS740_RS19900	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DS740_RS19905	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DS740_RS19910	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DS740_RS19915	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DS740_RS19920	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DS740_RS19925	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DS740_RS19935	COG0356	it plays a direct role in the translocation of protons across the membrane
DS740_RS19945	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DS740_RS19950	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DS740_RS19955	COG4475	Protein of unknown function (DUF436)
DS740_RS19960	COG0698	ribose 5-phosphate isomerase
DS740_RS19965	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DS740_RS19970	COG1971	Probably functions as a manganese efflux pump
DS740_RS19975	COG0009	L-threonylcarbamoyladenylate synthase
DS740_RS19980	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DS740_RS20000	COG2890	protein-(glutamine-N5) methyltransferase activity
DS740_RS20005	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DS740_RS20010	COG0346	lactoylglutathione lyase activity
DS740_RS20015	COG0789	Transcriptional regulator
DS740_RS20020	COG0679	Auxin Efflux Carrier
DS740_RS20025	COG0281	malic enzyme
DS740_RS20030	COG1435	thymidine kinase activity
DS740_RS20040	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DS740_RS20045	COG1494	fructose-1,6-bisphosphatase
DS740_RS20050	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DS740_RS20055	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DS740_RS20060	COG0191	fructose-bisphosphate aldolase activity
DS740_RS20065	COG2204	response regulator
DS740_RS20070	COG4821	SIS domain
DS740_RS20075	COG0504	CTP synthase activity
DS740_RS20080	COG3343	RNA polymerase activity
DS740_RS20085	COG1960	acyl-CoA dehydrogenase activity
DS740_RS20090	COG2181	nitrate reductase activity
DS740_RS20090	COG0247	lactate metabolic process
DS740_RS20095	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DS740_RS20100	COG4294	response to UV
DS740_RS20110	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DS740_RS20115	COG1132	(ABC) transporter
DS740_RS20120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DS740_RS20130	COG2181	nitrate reductase activity
DS740_RS20135	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
DS740_RS20140	COG1140	nitrate reductase beta subunit
DS740_RS20145	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DS740_RS20150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DS740_RS20160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DS740_RS20165	COG2223	nitrite transmembrane transporter activity
DS740_RS20170	COG0018	arginyl-trna synthetase
DS740_RS20175	COG4506	Protein conserved in bacteria
DS740_RS20190	COG0535	radical SAM domain protein
DS740_RS20200	COG1131	(ABC) transporter
DS740_RS20205	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DS740_RS20210	COG0612	Peptidase, M16
DS740_RS20215	COG0612	Peptidase, M16
DS740_RS20225	COG3391	amine dehydrogenase activity
DS740_RS20230	COG3391	amine dehydrogenase activity
DS740_RS20240	COG0457	Tetratricopeptide repeat
DS740_RS20270	COG1131	(ABC) transporter
DS740_RS20280	COG0010	Belongs to the arginase family
DS740_RS20285	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DS740_RS20290	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DS740_RS20305	COG1994	Peptidase M50
DS740_RS20310	COG1942	4-Oxalocrotonate Tautomerase
DS740_RS20315	COG1846	Transcriptional regulator
DS740_RS20320	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DS740_RS20325	COG0477	Major facilitator Superfamily
DS740_RS20330	COG1959	2 iron, 2 sulfur cluster binding
DS740_RS20335	COG3465	dGTPase activity
DS740_RS20340	COG1078	dGTPase activity
DS740_RS20345	COG4844	belongs to the
DS740_RS20355	COG0697	spore germination
DS740_RS20360	COG0095	Lipoate-protein ligase
DS740_RS20365	COG0583	DNA-binding transcription factor activity
DS740_RS20370	COG0280	phosphate acetyltransferase
DS740_RS20375	COG3253	May function as heme-dependent peroxidase
DS740_RS20380	COG1028	Short-chain dehydrogenase reductase Sdr
DS740_RS20385	COG0436	Aminotransferase
DS740_RS20390	COG2814	Major facilitator Superfamily
DS740_RS20395	COG0151	Belongs to the GarS family
DS740_RS20400	COG1028	Short-chain dehydrogenase reductase Sdr
DS740_RS20405	COG1917	Cupin 2, conserved barrel domain protein
DS740_RS20410	COG0077	Prephenate dehydratase
DS740_RS20415	COG2814	Major facilitator Superfamily
DS740_RS20420	COG0833	amino acid
DS740_RS20425	COG4187	Peptidase family M20/M25/M40
DS740_RS20430	COG1012	belongs to the aldehyde dehydrogenase family
DS740_RS20435	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DS740_RS20445	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
DS740_RS20450	COG1091	dTDP-4-dehydrorhamnose reductase activity
DS740_RS20455	COG1088	dTDP-glucose 4,6-dehydratase activity
DS740_RS20460	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DS740_RS20465	COG3980	spore coat polysaccharide biosynthesis protein
DS740_RS20470	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
DS740_RS20475	COG2089	acid synthase
DS740_RS20480	COG0456	acetyltransferase
DS740_RS20485	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DS740_RS20490	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DS740_RS20495	COG0463	Glycosyl transferase, family 2
DS740_RS20510	COG2363	Small membrane protein
DS740_RS20515	COG2233	PERMEase
DS740_RS20525	COG1012	belongs to the aldehyde dehydrogenase family
DS740_RS20530	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DS740_RS20535	COG1216	Glycosyl transferase, family 2
DS740_RS20550	COG1695	Transcriptional regulator
DS740_RS20555	COG0351	phosphomethylpyrimidine kinase
DS740_RS20565	COG1621	beta-fructofuranosidase activity
DS740_RS20570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DS740_RS20570	COG1263	PTS System
DS740_RS20575	COG2116	formate transmembrane transporter activity
DS740_RS20580	COG3711	transcriptional antiterminator
DS740_RS20590	COG1404	Belongs to the peptidase S8 family
DS740_RS20595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DS740_RS20600	COG0778	Nitroreductase
DS740_RS20605	COG0772	Belongs to the SEDS family
DS740_RS20615	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DS740_RS20620	COG1845	cytochrome c oxidase, subunit III
DS740_RS20625	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DS740_RS20630	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DS740_RS20635	COG2261	transglycosylase associated protein
DS740_RS20640	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
DS740_RS20645	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DS740_RS20650	COG2246	polysaccharide biosynthetic process
DS740_RS20655	COG1309	transcriptional regulator
DS740_RS20665	COG3162	membrane
DS740_RS20670	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DS740_RS20675	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DS740_RS20680	COG2837	iron assimilation
DS740_RS20685	COG2822	iron ion transport
DS740_RS20690	COG0672	)-iron permease
DS740_RS20695	COG0352	thiamine-phosphate diphosphorylase activity
DS740_RS20700	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DS740_RS20705	COG0583	DNA-binding transcription factor activity
DS740_RS20710	COG1380	Effector of murein hydrolase LrgA
DS740_RS20715	COG1346	cytolysis
DS740_RS20720	COG2814	Major facilitator Superfamily
DS740_RS20725	COG4895	conserved protein (DUF2196)
DS740_RS20730	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DS740_RS20735	COG0346	lactoylglutathione lyase activity
DS740_RS20740	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DS740_RS20745	COG1404	Belongs to the peptidase S8 family
DS740_RS20750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DS740_RS20750	COG1263	PTS System
DS740_RS20755	COG3711	transcriptional antiterminator
DS740_RS20760	COG1442	glycosyl transferase family 8
DS740_RS20765	COG5522	Integral membrane protein (intg_mem_TP0381)
DS740_RS20770	COG1846	Transcriptional regulator
DS740_RS20775	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DS740_RS20780	COG2234	aminopeptidase activity
DS740_RS20795	COG2814	Major facilitator Superfamily
DS740_RS20800	COG2357	RelA SpoT domain protein
DS740_RS20805	COG1575	Belongs to the MenA family. Type 1 subfamily
DS740_RS20820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DS740_RS20825	COG1696	Membrane protein involved in D-alanine export
DS740_RS20830	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DS740_RS20835	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DS740_RS20840	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
DS740_RS20845	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DS740_RS20850	COG1486	melibiose metabolic process
DS740_RS20855	COG1447	Phosphotransferase system cellobiose-specific component IIA
DS740_RS20860	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DS740_RS20865	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DS740_RS20870	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DS740_RS20870	COG3711	transcriptional antiterminator
DS740_RS20880	COG2094	Belongs to the DNA glycosylase MPG family
DS740_RS20885	COG0753	catalase activity
DS740_RS20890	COG2814	Major facilitator Superfamily
DS740_RS20895	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DS740_RS20900	COG1131	(ABC) transporter
DS740_RS20920	COG1595	DNA-templated transcription, initiation
DS740_RS20925	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DS740_RS20930	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DS740_RS20935	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DS740_RS20940	COG4988	ABC transporter
DS740_RS20945	COG1294	oxidase, subunit
DS740_RS20950	COG1271	oxidase subunit
DS740_RS20955	COG3493	citrate carrier protein
DS740_RS20960	COG0501	Belongs to the peptidase M48B family
DS740_RS20970	COG0726	polysaccharide deacetylase
DS740_RS20985	COG3842	ATPase activity
DS740_RS20990	COG2508	Transcriptional regulator
DS740_RS20995	COG1012	belongs to the aldehyde dehydrogenase family
DS740_RS21000	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DS740_RS21015	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DS740_RS21020	COG1881	PFAM PEBP family protein
DS740_RS21025	COG0583	DNA-binding transcription factor activity
DS740_RS21035	COG4585	Histidine kinase
DS740_RS21040	COG2197	response regulator
DS740_RS21045	COG2195	Cleaves the N-terminal amino acid of tripeptides
DS740_RS21055	COG4894	glucomannan catabolic process
DS740_RS21060	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DS740_RS21065	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DS740_RS21070	COG1028	Short-chain dehydrogenase reductase Sdr
DS740_RS21075	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DS740_RS21080	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DS740_RS21085	COG2610	gluconate transmembrane transporter activity
DS740_RS21090	COG0500	methyltransferase
DS740_RS21095	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DS740_RS21110	COG0693	protein deglycase activity
DS740_RS21110	COG0753	catalase activity
DS740_RS21115	COG2851	Citrate transporter
DS740_RS21120	COG2273	Hydrolase Family 16
DS740_RS21125	COG3711	transcriptional antiterminator
DS740_RS21135	COG2270	Major facilitator Superfamily
DS740_RS21140	COG0513	Belongs to the DEAD box helicase family
DS740_RS21145	COG2755	lipolytic protein G-D-S-L family
DS740_RS21145	COG3401	FG-GAP repeat protein
DS740_RS21190	COG3209	COG3209 Rhs family protein
DS740_RS21195	COG0697	spore germination
DS740_RS21200	COG0589	response to stress
DS740_RS21205	COG2723	6-phospho-beta-galactosidase activity
DS740_RS21210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DS740_RS21210	COG1263	PTS System
DS740_RS21210	COG2190	(PTS) system
DS740_RS21255	COG3507	Belongs to the glycosyl hydrolase 43 family
DS740_RS21270	COG2986	histidine ammonia-lyase
DS740_RS21275	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DS740_RS21280	COG1228	amidohydrolase
DS740_RS21285	COG0010	Belongs to the arginase family
DS740_RS21290	COG0833	amino acid
DS740_RS21295	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
DS740_RS21300	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DS740_RS21305	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DS740_RS21310	COG2390	Transcriptional regulator
DS740_RS21320	COG3192	ethanolamine utilization protein
DS740_RS21325	COG2079	MmgE PrpD family protein
DS740_RS21330	COG1473	amidohydrolase
DS740_RS21335	COG1126	abc transporter atp-binding protein
DS740_RS21340	COG0765	amino acid transport
DS740_RS21345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DS740_RS21350	COG0456	acetyltransferase
DS740_RS21355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DS740_RS21360	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
DS740_RS21365	COG0561	phosphatase activity
DS740_RS21395	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DS740_RS21400	COG5294	Protein conserved in bacteria
DS740_RS21405	COG0577	efflux transmembrane transporter activity
DS740_RS21410	COG1136	(ABC) transporter
DS740_RS21415	COG2205	protein histidine kinase activity
DS740_RS21420	COG0745	RESPONSE REGULATOR receiver
DS740_RS21425	COG0191	fructose-bisphosphate aldolase activity
DS740_RS21430	COG1082	Xylose isomerase domain protein TIM barrel
DS740_RS21435	COG1082	Xylose isomerase domain protein TIM barrel
DS740_RS21440	COG0673	inositol 2-dehydrogenase activity
DS740_RS21445	COG2814	Major facilitator Superfamily
DS740_RS21450	COG1082	Xylose isomerase domain protein TIM barrel
DS740_RS21455	COG3962	Belongs to the TPP enzyme family
DS740_RS21460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DS740_RS21470	COG1012	belongs to the aldehyde dehydrogenase family
DS740_RS21475	COG1349	DNA-binding transcription factor activity
DS740_RS21480	COG0667	Aldo Keto reductase
DS740_RS21495	COG2814	Major facilitator Superfamily
DS740_RS21500	COG0326	Molecular chaperone. Has ATPase activity
DS740_RS21510	COG1028	Short-chain dehydrogenase reductase Sdr
DS740_RS21540	COG1309	transcriptional regulator
DS740_RS21545	COG1012	belongs to the aldehyde dehydrogenase family
DS740_RS21550	COG1714	RDD family
DS740_RS21555	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DS740_RS21565	COG1714	RDD family
DS740_RS21570	COG2311	Membrane
DS740_RS21575	COG1917	Cupin 2, conserved barrel domain protein
DS740_RS21580	COG1309	transcriptional regulator
DS740_RS21585	COG1028	Short-chain dehydrogenase reductase Sdr
DS740_RS21590	COG1846	Transcriptional regulator
DS740_RS21595	COG1380	Effector of murein hydrolase LrgA
DS740_RS21600	COG1346	cytolysis
DS740_RS21605	COG5039	Polysaccharide pyruvyl transferase
DS740_RS21610	COG1929	Belongs to the glycerate kinase type-1 family
DS740_RS21615	COG1802	Transcriptional regulator
DS740_RS21620	COG1070	Carbohydrate kinase
DS740_RS21625	COG2610	gluconate transmembrane transporter activity
DS740_RS21630	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DS740_RS21635	COG0450	alkyl hydroperoxide reductase
DS740_RS21640	COG3634	alkyl hydroperoxide reductase activity
DS740_RS21660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DS740_RS21660	COG1263	PTS System
DS740_RS21665	COG2188	Transcriptional regulator
DS740_RS21680	COG1131	(ABC) transporter
DS740_RS21685	COG1994	Peptidase M50
DS740_RS21690	COG0535	radical SAM domain protein
DS740_RS21700	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
DS740_RS21710	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DS740_RS21725	COG1063	alcohol dehydrogenase
DS740_RS21745	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
DS740_RS21750	COG0456	acetyltransferase
DS740_RS21755	COG0457	Tetratricopeptide repeat
DS740_RS21765	COG0010	Belongs to the arginase family
DS740_RS21770	COG0833	amino acid
DS740_RS21775	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DS740_RS21780	COG3829	transcription factor binding
DS740_RS21790	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DS740_RS21795	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DS740_RS21800	COG4853	Protein conserved in bacteria
DS740_RS21805	COG4863	YycH protein
DS740_RS21810	COG5002	protein histidine kinase activity
DS740_RS21815	COG0745	RESPONSE REGULATOR receiver
DS740_RS21845	COG0346	lactoylglutathione lyase activity
DS740_RS21850	COG0305	Participates in initiation and elongation during chromosome replication
DS740_RS21865	COG3093	addiction module antidote protein HigA
DS740_RS21870	COG2807	transmembrane transport
DS740_RS21875	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DS740_RS21880	COG0359	binds to the 23S rRNA
DS740_RS21885	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
DS740_RS21890	COG4241	membrane
DS740_RS21900	COG5577	PFAM Coat F domain
DS740_RS21905	COG1733	regulation of RNA biosynthetic process
DS740_RS21910	COG1227	inorganic diphosphatase activity
DS740_RS21925	COG2271	Major facilitator Superfamily
DS740_RS21930	COG0789	Transcriptional regulator
DS740_RS21930	COG4978	Transcriptional regulator
DS740_RS21940	COG4319	ketosteroid isomerase
DS740_RS21950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DS740_RS21955	COG1846	Transcriptional regulator
DS740_RS21960	COG2153	protein acetylation
DS740_RS21965	COG2364	Membrane
DS740_RS21970	COG0456	acetyltransferase
DS740_RS21975	COG2315	Protein conserved in bacteria
DS740_RS21980	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DS740_RS22000	COG0789	Transcriptional regulator
DS740_RS22005	COG0697	spore germination
DS740_RS22010	COG1331	Highly conserved protein containing a thioredoxin domain
DS740_RS22015	COG1266	CAAX protease self-immunity
DS740_RS22020	COG0477	Major facilitator Superfamily
DS740_RS22020	COG2814	Major facilitator Superfamily
DS740_RS22025	COG0110	maltose O-acetyltransferase activity
DS740_RS22030	COG0346	lactoylglutathione lyase activity
DS740_RS22035	COG1609	Transcriptional regulator
DS740_RS22040	COG0708	Exodeoxyribonuclease III
DS740_RS22045	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DS740_RS22050	COG0629	single-stranded DNA binding
DS740_RS22055	COG0360	Binds together with S18 to 16S ribosomal RNA
DS740_RS22060	COG0012	GTP binding
DS740_RS22065	COG0243	molybdopterin cofactor binding
DS740_RS22070	COG4481	Protein conserved in bacteria
DS740_RS22075	COG3949	Membrane
DS740_RS22085	COG1475	DNA binding
DS740_RS22090	COG1192	Involved in chromosome partitioning
DS740_RS22100	COG1475	DNA binding
DS740_RS22105	COG0357	Ribosomal RNA small subunit methyltransferase G
DS740_RS22110	COG0445	tRNA wobble uridine modification
DS740_RS22115	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DS740_RS22120	COG1847	R3H domain protein
DS740_RS22125	COG0706	membrane insertase activity
DS740_RS22130	COG0594	ribonuclease P activity
DS740_RS22145	COG0587	DNA-directed DNA polymerase activity
DS740_RS22165	COG0328	RNA-DNA hybrid ribonuclease activity
DS740_RS22200	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DS740_RS22240	COG0716	FMN binding
DS740_RS22245	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DS740_RS22250	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DS740_RS22255	COG2887	Belongs to the helicase family. UvrD subfamily
DS740_RS22325	COG0582	viral genome integration into host DNA
DS740_RS22340	COG3584	3D domain protein
DS740_RS22340	COG1388	LysM domain
DS740_RS22360	COG0457	Tetratricopeptide repeat
DS740_RS22450	COG3953	SLT domain
DS740_RS22450	COG5280	Phage tail tape measure protein TP901
DS740_RS22505	COG5444	nuclease activity
DS740_RS22570	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DS740_RS22575	COG0187	DNA topoisomerase II activity
DS740_RS22620	COG0194	GDP metabolic process