locus-tag	class	description
A6J74_RS00020	COG0772	Belongs to the SEDS family
A6J74_RS00030	COG0741	lytic transglycosylase activity
A6J74_RS00045	COG0577	efflux transmembrane transporter activity
A6J74_RS00050	COG1136	(ABC) transporter
A6J74_RS00090	COG2318	DinB family
A6J74_RS00095	COG2378	regulation of single-species biofilm formation
A6J74_RS00205	COG0791	NLP P60 protein
A6J74_RS00205	COG3883	PFAM NLP P60 protein
A6J74_RS00500	COG1923	regulation of RNA biosynthetic process
A6J74_RS00505	COG0640	Transcriptional regulator
A6J74_RS00510	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A6J74_RS00540	COG3227	Zinc metalloprotease (Elastase)
A6J74_RS00550	COG1957	nucleoside hydrolase
A6J74_RS00575	COG1131	(ABC) transporter
A6J74_RS00595	COG1999	signal sequence binding
A6J74_RS00600	COG0662	Cupin 2, conserved barrel domain protein
A6J74_RS00610	COG0010	Belongs to the arginase family
A6J74_RS00620	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A6J74_RS00635	COG0456	acetyltransferase
A6J74_RS00660	COG3290	protein histidine kinase activity
A6J74_RS00665	COG4565	transcriptional regulatory protein
A6J74_RS00680	COG1136	(ABC) transporter
A6J74_RS00685	COG0577	efflux transmembrane transporter activity
A6J74_RS00695	COG0745	RESPONSE REGULATOR receiver
A6J74_RS00700	COG2205	protein histidine kinase activity
A6J74_RS00705	COG0753	catalase activity
A6J74_RS00725	COG0745	RESPONSE REGULATOR receiver
A6J74_RS00765	COG1136	(ABC) transporter
A6J74_RS00820	COG0640	Transcriptional regulator
A6J74_RS00825	COG0346	lactoylglutathione lyase activity
A6J74_RS00830	COG0798	PFAM Bile acid sodium symporter
A6J74_RS00870	COG2226	methyltransferase
A6J74_RS00880	COG4555	ABC transporter
A6J74_RS00900	COG0720	synthase
A6J74_RS00910	COG0302	gtp cyclohydrolase
A6J74_RS00975	COG4974	Belongs to the 'phage' integrase family
A6J74_RS00980	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A6J74_RS01000	COG0583	DNA-binding transcription factor activity
A6J74_RS01030	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
A6J74_RS01045	COG5002	protein histidine kinase activity
A6J74_RS01055	COG3338	carbonate dehydratase activity
A6J74_RS01075	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
A6J74_RS01075	COG2755	lipolytic protein G-D-S-L family
A6J74_RS01090	COG0686	Belongs to the AlaDH PNT family
A6J74_RS01095	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
A6J74_RS01095	COG2508	Transcriptional regulator
A6J74_RS01165	COG1329	Transcriptional regulator
A6J74_RS01265	COG0358	DNA primase activity
A6J74_RS01270	COG1132	(ABC) transporter
A6J74_RS01345	COG3011	Protein conserved in bacteria
A6J74_RS01505	COG1923	regulation of RNA biosynthetic process
A6J74_RS01580	COG0753	catalase activity
A6J74_RS01610	COG0714	Associated with various cellular activities
A6J74_RS01635	COG0346	lactoylglutathione lyase activity
A6J74_RS01640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A6J74_RS01670	COG3655	Transcriptional regulator
A6J74_RS01680	COG1349	DNA-binding transcription factor activity
A6J74_RS01685	COG1175	transmembrane transport
A6J74_RS01710	COG3842	ATPase activity
A6J74_RS01720	COG1785	Belongs to the alkaline phosphatase family
A6J74_RS01725	COG2720	vancomycin resistance protein
A6J74_RS01730	COG3239	Fatty acid desaturase
A6J74_RS01740	COG0833	amino acid
A6J74_RS01745	COG1414	Transcriptional regulator
A6J74_RS01750	COG4187	Peptidase family M20/M25/M40
A6J74_RS01755	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A6J74_RS01765	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
A6J74_RS01770	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
A6J74_RS01775	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A6J74_RS01780	COG2207	Transcriptional regulator
A6J74_RS01785	COG1472	Belongs to the glycosyl hydrolase 3 family
A6J74_RS01805	COG2329	Antibiotic biosynthesis monooxygenase
A6J74_RS01835	COG1070	Carbohydrate kinase
A6J74_RS01840	COG2390	Transcriptional regulator
A6J74_RS01850	COG1172	Belongs to the binding-protein-dependent transport system permease family
A6J74_RS01855	COG1172	Belongs to the binding-protein-dependent transport system permease family
A6J74_RS01880	COG0431	NADPH-dependent FMN reductase
A6J74_RS01885	COG0519	Catalyzes the synthesis of GMP from XMP
A6J74_RS01890	COG0346	lactoylglutathione lyase activity
A6J74_RS01900	COG3584	3D domain protein
A6J74_RS01900	COG1388	LysM domain
A6J74_RS01945	COG1605	Chorismate mutase
A6J74_RS01945	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
A6J74_RS01965	COG0287	Prephenate dehydrogenase
A6J74_RS01980	COG1051	belongs to the nudix hydrolase family
A6J74_RS01985	COG1309	transcriptional regulator
A6J74_RS01990	COG2409	Drug exporters of the RND superfamily
A6J74_RS01990	COG1033	growth of symbiont in host cell
A6J74_RS01995	COG0488	(ABC) transporter
A6J74_RS02000	COG1368	sulfuric ester hydrolase activity
A6J74_RS02005	COG0861	Integral membrane protein TerC family
A6J74_RS02010	COG2814	Major facilitator Superfamily
A6J74_RS02035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A6J74_RS02040	COG0346	lactoylglutathione lyase activity
A6J74_RS02045	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A6J74_RS02075	COG0697	spore germination
A6J74_RS02110	COG2746	aminoglycoside 3-N-acetyltransferase activity
A6J74_RS02140	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A6J74_RS02145	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A6J74_RS02150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A6J74_RS02165	COG0628	permease
A6J74_RS02215	COG1131	(ABC) transporter
A6J74_RS02230	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
A6J74_RS02240	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
A6J74_RS02245	COG0436	Aminotransferase
A6J74_RS02285	COG2226	methyltransferase
A6J74_RS02300	COG2261	transglycosylase associated protein
A6J74_RS02325	COG0477	Major facilitator Superfamily
A6J74_RS02325	COG2814	Major facilitator Superfamily
A6J74_RS02330	COG4533	DNA binding
A6J74_RS02335	COG0789	Transcriptional regulator
A6J74_RS02340	COG1664	Polymer-forming cytoskeletal
A6J74_RS02350	COG2814	Major facilitator Superfamily
A6J74_RS02400	COG1307	EDD domain protein, DegV family
A6J74_RS02405	COG0456	acetyltransferase
A6J74_RS02410	COG1164	Oligoendopeptidase f
A6J74_RS02435	COG0745	RESPONSE REGULATOR receiver
A6J74_RS02440	COG5002	protein histidine kinase activity
A6J74_RS02440	COG3850	Histidine kinase
A6J74_RS02445	COG2936	dipeptidyl-peptidase activity
A6J74_RS02495	COG4948	Mandelate Racemase Muconate Lactonizing
A6J74_RS02505	COG4166	transmembrane transport
A6J74_RS02510	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
A6J74_RS02525	COG0586	Pfam SNARE associated Golgi protein
A6J74_RS02530	COG1078	dGTPase activity
A6J74_RS02580	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A6J74_RS02585	COG3938	Belongs to the proline racemase family
A6J74_RS02590	COG3938	Belongs to the proline racemase family
A6J74_RS02595	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A6J74_RS02600	COG1012	belongs to the aldehyde dehydrogenase family
A6J74_RS02605	COG1115	amino acid carrier protein
A6J74_RS02610	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A6J74_RS02615	COG1162	GTPase activity
A6J74_RS02630	COG2318	DinB family
A6J74_RS02635	COG3397	chitin binding
A6J74_RS02650	COG4637	Psort location Cytoplasmic, score
A6J74_RS02680	COG0514	ATP-dependent DNA helicase (RecQ)
A6J74_RS02690	COG3973	AAA domain
A6J74_RS02740	COG2315	Protein conserved in bacteria
A6J74_RS02745	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A6J74_RS02750	COG2205	protein histidine kinase activity
A6J74_RS02770	COG1819	glycosyl
A6J74_RS02780	COG3397	chitin binding
A6J74_RS02795	COG2153	protein acetylation
A6J74_RS02825	COG4175	Glycine betaine
A6J74_RS02825	COG0517	IMP dehydrogenase activity
A6J74_RS02830	COG4176	ABC-type proline glycine betaine transport system permease component
A6J74_RS02860	COG1028	Short-chain dehydrogenase reductase Sdr
A6J74_RS02870	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A6J74_RS02875	COG0022	dehydrogenase e1 component
A6J74_RS02880	COG0508	dehydrogenase complex catalyzes the overall conversion of
A6J74_RS02885	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A6J74_RS02905	COG1349	DNA-binding transcription factor activity
A6J74_RS02925	COG3284	Transcriptional regulator
A6J74_RS02935	COG1309	transcriptional regulator
A6J74_RS02975	COG2959	enzyme of heme biosynthesis
A6J74_RS02990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A6J74_RS03025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A6J74_RS03030	COG0697	spore germination
A6J74_RS03035	COG0201	protein transport
A6J74_RS03045	COG0737	Belongs to the 5'-nucleotidase family
A6J74_RS03050	COG3227	Zinc metalloprotease (Elastase)
A6J74_RS03055	COG1523	belongs to the glycosyl hydrolase 13 family
A6J74_RS03075	COG0076	glutamate decarboxylase activity
A6J74_RS03080	COG0657	acetylesterase activity
A6J74_RS03100	COG0577	efflux transmembrane transporter activity
A6J74_RS03105	COG1136	(ABC) transporter
A6J74_RS03145	COG5002	protein histidine kinase activity
A6J74_RS03150	COG0745	RESPONSE REGULATOR receiver
A6J74_RS03155	COG1011	Hydrolase
A6J74_RS03180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A6J74_RS03210	COG0322	excinuclease ABC activity
A6J74_RS03250	COG4667	esterase of the alpha-beta hydrolase superfamily
A6J74_RS03275	COG3878	Protein conserved in bacteria
A6J74_RS03300	COG0592	DNA-directed DNA polymerase activity
A6J74_RS03305	COG2816	NAD+ diphosphatase activity
A6J74_RS03315	COG2223	nitrite transmembrane transporter activity
A6J74_RS03325	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A6J74_RS03355	COG0697	spore germination
A6J74_RS03360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A6J74_RS03380	COG0584	glycerophosphoryl diester phosphodiesterase
A6J74_RS03400	COG2814	Major facilitator Superfamily
A6J74_RS03410	COG0789	Transcriptional regulator
A6J74_RS03465	COG0768	penicillin binding
A6J74_RS03470	COG0671	phosphoesterase, PA-phosphatase related
A6J74_RS03475	COG0604	alcohol dehydrogenase
A6J74_RS03480	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
A6J74_RS03490	COG2205	protein histidine kinase activity
A6J74_RS03515	COG1794	racemase activity, acting on amino acids and derivatives
A6J74_RS03520	COG1819	glycosyl
A6J74_RS03530	COG0768	penicillin binding
A6J74_RS03535	COG5002	protein histidine kinase activity
A6J74_RS03540	COG0561	phosphatase activity
A6J74_RS03575	COG2124	cytochrome p450
A6J74_RS03660	COG5632	N-Acetylmuramoyl-L-alanine amidase
A6J74_RS03735	COG0740	serine-type endopeptidase activity
A6J74_RS03745	COG4626	Terminase
A6J74_RS03745	COG1802	Transcriptional regulator
A6J74_RS03775	COG0582	viral genome integration into host DNA
A6J74_RS03780	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
A6J74_RS03835	COG1484	DNA-dependent DNA replication
A6J74_RS03875	COG0582	viral genome integration into host DNA
A6J74_RS03930	COG0582	viral genome integration into host DNA
A6J74_RS04075	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
A6J74_RS04085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A6J74_RS04115	COG0577	efflux transmembrane transporter activity
A6J74_RS04120	COG1136	(ABC) transporter
A6J74_RS04130	COG0488	(ABC) transporter
A6J74_RS04135	COG0667	Aldo Keto reductase
A6J74_RS04140	COG0583	DNA-binding transcription factor activity
A6J74_RS04150	COG2205	protein histidine kinase activity
A6J74_RS04155	COG0745	RESPONSE REGULATOR receiver
A6J74_RS04165	COG3773	Cell wall hydrolase
A6J74_RS04170	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
A6J74_RS04180	COG3386	PFAM SMP-30 Gluconolaconase
A6J74_RS04190	COG0693	protein deglycase activity
A6J74_RS04200	COG2323	membrane
A6J74_RS04225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A6J74_RS04230	COG0697	spore germination
A6J74_RS04255	COG0583	DNA-binding transcription factor activity
A6J74_RS04260	COG1942	4-Oxalocrotonate Tautomerase
A6J74_RS04270	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A6J74_RS04280	COG2226	methyltransferase
A6J74_RS04285	COG1733	regulation of RNA biosynthetic process
A6J74_RS04300	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A6J74_RS04330	COG2207	Transcriptional regulator
A6J74_RS04335	COG3227	Zinc metalloprotease (Elastase)
A6J74_RS04360	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A6J74_RS04385	COG1686	Belongs to the peptidase S11 family
A6J74_RS04390	COG2318	DinB family
A6J74_RS04450	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A6J74_RS04455	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A6J74_RS04460	COG1024	Enoyl-CoA hydratase
A6J74_RS04465	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A6J74_RS04470	COG0511	ligase activity, forming carbon-carbon bonds
A6J74_RS04475	COG0439	Biotin carboxylase
A6J74_RS04480	COG1960	acyl-CoA dehydrogenase activity
A6J74_RS04490	COG1309	transcriptional regulator
A6J74_RS04500	COG1131	(ABC) transporter
A6J74_RS04525	COG0823	Involved in the tonB-independent uptake of proteins
A6J74_RS04530	COG3397	chitin binding
A6J74_RS04545	COG0697	spore germination
A6J74_RS04590	COG0768	penicillin binding
A6J74_RS04595	COG0768	penicillin binding
A6J74_RS04605	COG1595	DNA-templated transcription, initiation
A6J74_RS04610	COG0768	penicillin binding
A6J74_RS04630	COG1686	Belongs to the peptidase S11 family
A6J74_RS04635	COG0110	maltose O-acetyltransferase activity
A6J74_RS04640	COG0730	response to heat
A6J74_RS04650	COG2002	toxin-antitoxin pair type II binding
A6J74_RS04680	COG2195	Cleaves the N-terminal amino acid of tripeptides
A6J74_RS04720	COG3961	Belongs to the TPP enzyme family
A6J74_RS04725	COG2226	methyltransferase
A6J74_RS04755	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A6J74_RS04790	COG2971	BadF BadG BcrA BcrD
A6J74_RS04795	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
A6J74_RS04815	COG1649	PFAM Uncharacterised BCR, COG1649
A6J74_RS04845	COG1595	DNA-templated transcription, initiation
A6J74_RS04850	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
A6J74_RS04885	COG1396	sequence-specific DNA binding
A6J74_RS04900	COG1132	(ABC) transporter
A6J74_RS04905	COG1132	(ABC) transporter
A6J74_RS04920	COG2258	MOSC domain
A6J74_RS04925	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A6J74_RS04930	COG0583	DNA-binding transcription factor activity
A6J74_RS04935	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A6J74_RS04940	COG0583	DNA-binding transcription factor activity
A6J74_RS04970	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A6J74_RS04980	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
A6J74_RS05005	COG1247	-acetyltransferase
A6J74_RS05030	COG1309	transcriptional regulator
A6J74_RS05035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A6J74_RS05045	COG1846	Transcriptional regulator
A6J74_RS05065	COG0745	RESPONSE REGULATOR receiver
A6J74_RS05075	COG5002	protein histidine kinase activity
A6J74_RS05090	COG2755	lipolytic protein G-D-S-L family
A6J74_RS05090	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
A6J74_RS05115	COG2207	Transcriptional regulator
A6J74_RS05125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A6J74_RS05160	COG0028	Belongs to the TPP enzyme family
A6J74_RS05175	COG0596	Alpha beta hydrolase
A6J74_RS05185	COG1136	(ABC) transporter
A6J74_RS05190	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A6J74_RS05195	COG1187	pseudouridine synthase activity
A6J74_RS05200	COG2329	Antibiotic biosynthesis monooxygenase
A6J74_RS05215	COG1115	amino acid carrier protein
A6J74_RS05240	COG2318	DinB family
A6J74_RS05250	COG0776	regulation of translation
A6J74_RS05265	COG2814	Major facilitator Superfamily
A6J74_RS05270	COG3251	PFAM MbtH domain protein
A6J74_RS05275	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A6J74_RS05280	COG1535	isochorismatase
A6J74_RS05280	COG3433	isochorismatase activity
A6J74_RS05285	COG1021	2,3-dihydroxybenzoate-AMP ligase
A6J74_RS05290	COG1169	isochorismate synthase
A6J74_RS05295	COG1028	Short-chain dehydrogenase reductase Sdr
A6J74_RS05300	COG2223	nitrite transmembrane transporter activity
A6J74_RS05330	COG0420	3'-5' exonuclease activity
A6J74_RS05345	COG1024	Enoyl-CoA hydratase
A6J74_RS05350	COG1280	lysine exporter protein (LysE YggA)
A6J74_RS05360	COG2084	Dehydrogenase
A6J74_RS05365	COG1960	acyl-CoA dehydrogenase activity
A6J74_RS05370	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
A6J74_RS05375	COG2079	MmgE PrpD family protein
A6J74_RS05380	COG0372	Belongs to the citrate synthase family
A6J74_RS05390	COG2814	Major facilitator Superfamily
A6J74_RS05400	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A6J74_RS05400	COG4499	WXG100 protein secretion system (Wss), protein YukC
A6J74_RS05420	COG1028	Short-chain dehydrogenase reductase Sdr
A6J74_RS05445	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A6J74_RS05500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A6J74_RS05505	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A6J74_RS05510	COG0671	phosphoesterase, PA-phosphatase related
A6J74_RS05520	COG3064	Membrane
A6J74_RS05520	COG0515	serine threonine protein kinase
A6J74_RS05520	COG4991	sh3 domain protein
A6J74_RS05555	COG1509	lysine 2,3-aminomutase activity
A6J74_RS05560	COG3829	transcription factor binding
A6J74_RS05565	COG0456	acetyltransferase
A6J74_RS05570	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A6J74_RS05575	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
A6J74_RS05580	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
A6J74_RS05585	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A6J74_RS05600	COG5506	Protein of unknown function (DUF1694)
A6J74_RS05605	COG1012	belongs to the aldehyde dehydrogenase family
A6J74_RS05610	COG1253	flavin adenine dinucleotide binding
A6J74_RS05645	COG1174	glycine betaine transport
A6J74_RS05650	COG1125	glycine betaine transport
A6J74_RS05650	COG0517	IMP dehydrogenase activity
A6J74_RS05685	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
A6J74_RS05695	COG1070	Carbohydrate kinase
A6J74_RS05725	COG1064	alcohol dehydrogenase
A6J74_RS05730	COG1737	Transcriptional regulator
A6J74_RS05735	COG2197	response regulator
A6J74_RS05740	COG2203	Gaf domain
A6J74_RS05740	COG4585	Histidine kinase
A6J74_RS05745	COG0668	transmembrane transport
A6J74_RS05750	COG1051	belongs to the nudix hydrolase family
A6J74_RS05755	COG1335	isochorismatase
A6J74_RS05775	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A6J74_RS05780	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A6J74_RS05785	COG0860	N-Acetylmuramoyl-L-alanine amidase
A6J74_RS05800	COG0367	asparagine synthase
A6J74_RS05805	COG0071	Belongs to the small heat shock protein (HSP20) family
A6J74_RS05810	COG1999	signal sequence binding
A6J74_RS05815	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A6J74_RS05820	COG1307	EDD domain protein, DegV family
A6J74_RS05835	COG0805	protein transport
A6J74_RS05845	COG1272	protein, Hemolysin III
A6J74_RS05850	COG0204	Acyl-transferase
A6J74_RS05860	COG0768	penicillin binding
A6J74_RS05875	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A6J74_RS05890	COG0546	phosphoglycolate phosphatase activity
A6J74_RS05905	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
A6J74_RS05910	COG0456	acetyltransferase
A6J74_RS05920	COG1794	racemase activity, acting on amino acids and derivatives
A6J74_RS05930	COG2610	gluconate transmembrane transporter activity
A6J74_RS05955	COG0733	neurotransmitter:sodium symporter activity
A6J74_RS05960	COG0017	Asparaginyl-tRNA synthetase
A6J74_RS05995	COG0018	arginyl-trna synthetase
A6J74_RS06000	COG2521	methyltransferase
A6J74_RS06000	COG2136	Putative SAM-dependent methyltransferase
A6J74_RS06015	COG1413	lyase activity
A6J74_RS06030	COG0629	single-stranded DNA binding
A6J74_RS06045	COG0488	(ABC) transporter
A6J74_RS06050	COG1418	mRNA catabolic process
A6J74_RS06060	COG2359	stage V sporulation protein S
A6J74_RS06105	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A6J74_RS06115	COG0582	viral genome integration into host DNA
A6J74_RS06145	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
A6J74_RS06150	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A6J74_RS06155	COG2146	nitrite reductase [NAD(P)H] activity
A6J74_RS06160	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A6J74_RS06160	COG1587	Uroporphyrinogen-III synthase
A6J74_RS06185	COG2223	nitrite transmembrane transporter activity
A6J74_RS06195	COG0314	molybdopterin synthase activity
A6J74_RS06200	COG0303	'Molybdopterin
A6J74_RS06205	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A6J74_RS06210	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A6J74_RS06215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A6J74_RS06220	COG2181	nitrate reductase activity
A6J74_RS06225	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
A6J74_RS06230	COG1140	nitrate reductase beta subunit
A6J74_RS06235	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
A6J74_RS06240	COG0714	Associated with various cellular activities
A6J74_RS06245	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
A6J74_RS06250	COG1305	Transglutaminase-like
A6J74_RS06255	COG0386	Belongs to the glutathione peroxidase family
A6J74_RS06265	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A6J74_RS06265	COG0426	domain, Protein
A6J74_RS06285	COG1595	DNA-templated transcription, initiation
A6J74_RS06300	COG0346	lactoylglutathione lyase activity
A6J74_RS06320	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A6J74_RS06345	COG3874	Sporulation protein YtfJ
A6J74_RS06355	COG4974	Belongs to the 'phage' integrase family
A6J74_RS06520	COG4499	WXG100 protein secretion system (Wss), protein YukC
A6J74_RS06555	COG0456	acetyltransferase
A6J74_RS06580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A6J74_RS06585	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A6J74_RS06590	COG1819	glycosyl
A6J74_RS06605	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A6J74_RS06615	COG2814	Major facilitator Superfamily
A6J74_RS06620	COG1846	Transcriptional regulator
A6J74_RS06625	COG0561	phosphatase activity
A6J74_RS06635	COG0860	N-Acetylmuramoyl-L-alanine amidase
A6J74_RS06650	COG2211	Major facilitator Superfamily
A6J74_RS06655	COG0154	amidase activity
A6J74_RS06665	COG1876	peptidase activity
A6J74_RS06680	COG0860	N-Acetylmuramoyl-L-alanine amidase
A6J74_RS06700	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A6J74_RS06705	COG1114	Component of the transport system for branched-chain amino acids
A6J74_RS06720	COG1253	flavin adenine dinucleotide binding
A6J74_RS06725	COG2839	Protein conserved in bacteria
A6J74_RS06730	COG0702	epimerase
A6J74_RS06745	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A6J74_RS06755	COG1607	acyl-coa hydrolase
A6J74_RS06760	COG3689	TIGRFAM TIGR03943 family protein
A6J74_RS06765	COG0701	Predicted permease
A6J74_RS06775	COG2244	polysaccharide biosynthetic process
A6J74_RS06780	COG0586	Pfam SNARE associated Golgi protein
A6J74_RS06785	COG1051	belongs to the nudix hydrolase family
A6J74_RS06790	COG5337	Spore coat protein CotH
A6J74_RS06800	COG0406	alpha-ribazole phosphatase activity
A6J74_RS06810	COG0346	lactoylglutathione lyase activity
A6J74_RS06815	COG4166	transmembrane transport
A6J74_RS06825	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A6J74_RS06835	COG0702	epimerase
A6J74_RS06840	COG0803	Belongs to the bacterial solute-binding protein 9 family
A6J74_RS06850	COG0523	cobalamin synthesis protein
A6J74_RS06855	COG4989	oxidoreductase activity
A6J74_RS06860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A6J74_RS06865	COG1231	oxidoreductase activity
A6J74_RS06880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A6J74_RS06895	COG0783	Belongs to the Dps family
A6J74_RS06900	COG3949	Membrane
A6J74_RS06945	COG0667	Aldo Keto reductase
A6J74_RS06950	COG0640	Transcriptional regulator
A6J74_RS06955	COG1404	Belongs to the peptidase S8 family
A6J74_RS06960	COG2002	toxin-antitoxin pair type II binding
A6J74_RS06965	COG0577	efflux transmembrane transporter activity
A6J74_RS07000	COG1752	Esterase of the alpha-beta hydrolase superfamily
A6J74_RS07010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A6J74_RS07015	COG1279	arginine transmembrane transporter activity
A6J74_RS07020	COG2814	Major facilitator Superfamily
A6J74_RS07030	COG1082	Xylose isomerase domain protein TIM barrel
A6J74_RS07040	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A6J74_RS07060	COG1247	-acetyltransferase
A6J74_RS07065	COG1285	pathogenesis
A6J74_RS07080	COG5002	protein histidine kinase activity
A6J74_RS07085	COG0745	RESPONSE REGULATOR receiver
A6J74_RS07095	COG1316	TRANSCRIPTIONal
A6J74_RS07110	COG0083	homoserine kinase activity
A6J74_RS07120	COG0460	homoserine dehydrogenase
A6J74_RS07140	COG5658	integral membrane protein
A6J74_RS07165	COG0300	oxidoreductase activity
A6J74_RS07170	COG5002	protein histidine kinase activity
A6J74_RS07175	COG0745	RESPONSE REGULATOR receiver
A6J74_RS07180	COG1132	(ABC) transporter
A6J74_RS07190	COG0791	NLP P60 protein
A6J74_RS07190	COG1388	LysM domain
A6J74_RS07205	COG1686	Belongs to the peptidase S11 family
A6J74_RS07225	COG1216	Glycosyl transferase, family 2
A6J74_RS07230	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
A6J74_RS07235	COG4988	ABC transporter
A6J74_RS07240	COG1294	oxidase, subunit
A6J74_RS07245	COG1271	oxidase subunit
A6J74_RS07275	COG0583	DNA-binding transcription factor activity
A6J74_RS07295	COG0411	ABC transporter
A6J74_RS07305	COG0523	cobalamin synthesis protein
A6J74_RS07310	COG1231	oxidoreductase activity
A6J74_RS07325	COG0628	permease
A6J74_RS07340	COG0778	Nitroreductase
A6J74_RS07345	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
A6J74_RS07350	COG1959	2 iron, 2 sulfur cluster binding
A6J74_RS07355	COG0583	DNA-binding transcription factor activity
A6J74_RS07360	COG0697	spore germination
A6J74_RS07365	COG4549	nuclear export factor GLE1
A6J74_RS07370	COG2372	response to copper ion
A6J74_RS07370	COG1276	copper resistance
A6J74_RS07380	COG1114	Component of the transport system for branched-chain amino acids
A6J74_RS07400	COG0583	DNA-binding transcription factor activity
A6J74_RS07410	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A6J74_RS07465	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A6J74_RS07475	COG2239	Acts as a magnesium transporter
A6J74_RS07480	COG0772	Belongs to the SEDS family
A6J74_RS07515	COG2205	protein histidine kinase activity
A6J74_RS07520	COG0745	RESPONSE REGULATOR receiver
A6J74_RS07525	COG0577	efflux transmembrane transporter activity
A6J74_RS07530	COG1136	(ABC) transporter
A6J74_RS07550	COG0814	amino acid
A6J74_RS07555	COG1760	l-serine dehydratase
A6J74_RS07560	COG1760	l-serine dehydratase
A6J74_RS07615	COG1073	alpha beta
A6J74_RS07625	COG2132	Multicopper oxidase
A6J74_RS07630	COG0006	proline dipeptidase activity
A6J74_RS07645	COG0583	DNA-binding transcription factor activity
A6J74_RS07665	COG4846	Membrane protein involved in cytochrome C biogenesis
A6J74_RS07675	COG0295	cytidine deaminase activity
A6J74_RS07680	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
A6J74_RS07685	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A6J74_RS07695	COG2390	Transcriptional regulator
A6J74_RS07700	COG1309	transcriptional regulator
A6J74_RS07705	COG1266	CAAX protease self-immunity
A6J74_RS07735	COG0531	amino acid
A6J74_RS07740	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A6J74_RS07755	COG1914	H( )-stimulated, divalent metal cation uptake system
A6J74_RS07775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A6J74_RS07780	COG0535	radical SAM domain protein
A6J74_RS07795	COG4166	transmembrane transport
A6J74_RS07815	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A6J74_RS07825	COG3384	dioxygenase
A6J74_RS07830	COG2814	Major facilitator Superfamily
A6J74_RS07855	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A6J74_RS07875	COG0028	Belongs to the TPP enzyme family
A6J74_RS07880	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A6J74_RS07890	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A6J74_RS07915	COG2323	membrane
A6J74_RS07920	COG5566	PFAM Mor transcription activator
A6J74_RS07930	COG0733	neurotransmitter:sodium symporter activity
A6J74_RS07935	COG2244	polysaccharide biosynthetic process
A6J74_RS07950	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A6J74_RS07955	COG2223	nitrite transmembrane transporter activity
A6J74_RS07960	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A6J74_RS07970	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A6J74_RS07975	COG0477	Major facilitator Superfamily
A6J74_RS07985	COG1695	Transcriptional regulator
A6J74_RS08010	COG2814	Major facilitator Superfamily
A6J74_RS08045	COG3620	sequence-specific DNA binding
A6J74_RS08070	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A6J74_RS08080	COG1846	Transcriptional regulator
A6J74_RS08085	COG0784	Response regulator, receiver
A6J74_RS08090	COG4191	Histidine kinase
A6J74_RS08095	COG0281	malic enzyme
A6J74_RS08100	COG1027	Aspartate ammonia-lyase
A6J74_RS08110	COG0528	UMP kinase activity
A6J74_RS08115	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A6J74_RS08130	COG1131	(ABC) transporter
A6J74_RS08170	COG2733	membrane
A6J74_RS08190	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A6J74_RS08195	COG0785	Cytochrome C biogenesis protein
A6J74_RS08215	COG3340	Belongs to the peptidase S51 family
A6J74_RS08220	COG0534	Mate efflux family protein
A6J74_RS08240	COG4221	oxidoreductase activity
A6J74_RS08245	COG0789	Transcriptional regulator
A6J74_RS08250	COG1757	Na H antiporter
A6J74_RS08255	COG0438	transferase activity, transferring glycosyl groups
A6J74_RS08255	COG1216	Glycosyl transferase, family 2
A6J74_RS08260	COG0523	cobalamin synthesis protein
A6J74_RS08270	COG0697	spore germination
A6J74_RS08275	COG1802	Transcriptional regulator
A6J74_RS08305	COG0367	asparagine synthase
A6J74_RS08315	COG1846	Transcriptional regulator
A6J74_RS08335	COG0406	alpha-ribazole phosphatase activity
A6J74_RS08370	COG1234	tRNA 3'-trailer cleavage
A6J74_RS08380	COG1840	ABC-type Fe3 transport system, periplasmic component
A6J74_RS08385	COG3842	ATPase activity
A6J74_RS08390	COG0583	DNA-binding transcription factor activity
A6J74_RS08400	COG2814	Major facilitator Superfamily
A6J74_RS08415	COG2329	Antibiotic biosynthesis monooxygenase
A6J74_RS08455	COG4787	bacterial-type flagellum-dependent cell motility
A6J74_RS08460	COG1419	protein localization to endoplasmic reticulum
A6J74_RS08465	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A6J74_RS08470	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A6J74_RS08480	COG1987	bacterial-type flagellum assembly
A6J74_RS08485	COG1338	Plays a role in the flagellum-specific transport system
A6J74_RS08495	COG1776	CheC inhibitor of MCP methylation
A6J74_RS08495	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A6J74_RS08500	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A6J74_RS08510	COG0741	lytic transglycosylase activity
A6J74_RS08515	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A6J74_RS08515	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A6J74_RS08520	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A6J74_RS08530	COG0835	chemotaxis
A6J74_RS08530	COG0784	Response regulator, receiver
A6J74_RS08545	COG1749	Flagellar hook protein flgE
A6J74_RS08565	COG1157	protein secretion by the type III secretion system
A6J74_RS08575	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A6J74_RS08580	COG1766	The M ring may be actively involved in energy transduction
A6J74_RS08590	COG1558	bacterial-type flagellum-dependent cell motility
A6J74_RS08595	COG1815	bacterial-type flagellum-dependent cell motility
A6J74_RS08610	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
A6J74_RS08615	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A6J74_RS08620	COG1256	bacterial-type flagellum assembly
A6J74_RS08640	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
A6J74_RS08655	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A6J74_RS08655	COG1776	CheC inhibitor of MCP methylation
A6J74_RS08660	COG0643	Histidine kinase
A6J74_RS08660	COG2198	Histidine kinase
A6J74_RS08665	COG2201	protein-glutamate methylesterase activity
A6J74_RS08670	COG1360	Flagellar Motor Protein
A6J74_RS08675	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
A6J74_RS08685	COG1923	regulation of RNA biosynthetic process
A6J74_RS08705	COG2814	Major facilitator Superfamily
A6J74_RS08735	COG1434	Gram-negative-bacterium-type cell wall biogenesis
A6J74_RS08740	COG2323	membrane
A6J74_RS08750	COG0789	Transcriptional regulator
A6J74_RS08750	COG4978	Transcriptional regulator
A6J74_RS08755	COG0475	glutathione-regulated potassium exporter activity
A6J74_RS08765	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A6J74_RS08770	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A6J74_RS08775	COG3162	membrane
A6J74_RS08790	COG1280	lysine exporter protein (LysE YggA)
A6J74_RS08795	COG3403	YqcI/YcgG family
A6J74_RS08830	COG0328	RNA-DNA hybrid ribonuclease activity
A6J74_RS08850	COG0454	-acetyltransferase
A6J74_RS08865	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A6J74_RS08880	COG0754	glutathionylspermidine amidase activity
A6J74_RS08925	COG0456	acetyltransferase
A6J74_RS08935	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
A6J74_RS08945	COG2311	Membrane
A6J74_RS08950	COG2233	PERMEase
A6J74_RS08960	COG0024	Methionine aminopeptidase
A6J74_RS08965	COG3173	Aminoglycoside phosphotransferase
A6J74_RS08975	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
A6J74_RS08980	COG1199	ATP-dependent helicase activity
A6J74_RS08990	COG0116	Belongs to the methyltransferase superfamily
A6J74_RS09000	COG3599	regulation of cell shape
A6J74_RS09050	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A6J74_RS09050	COG4499	WXG100 protein secretion system (Wss), protein YukC
A6J74_RS09060	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A6J74_RS09065	COG3935	DnaD domain protein
A6J74_RS09085	COG1199	ATP-dependent helicase activity
A6J74_RS09085	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A6J74_RS09125	COG0438	transferase activity, transferring glycosyl groups
A6J74_RS09130	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A6J74_RS09145	COG1694	Mazg nucleotide pyrophosphohydrolase
A6J74_RS09150	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A6J74_RS09160	COG2738	Putative neutral zinc metallopeptidase
A6J74_RS09175	COG4347	Protein of unknown function (DUF1405)
A6J74_RS09185	COG2010	Cytochrome c
A6J74_RS09185	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
A6J74_RS09190	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
A6J74_RS09210	COG0457	Tetratricopeptide repeat
A6J74_RS09235	COG0142	geranyltranstransferase activity
A6J74_RS09245	COG0142	geranyltranstransferase activity
A6J74_RS09260	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
A6J74_RS09335	COG0492	ferredoxin-NADP+ reductase activity
A6J74_RS09355	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A6J74_RS09360	COG4862	establishment of competence for transformation
A6J74_RS09365	COG0789	Transcriptional regulator
A6J74_RS09370	COG1408	metallophosphoesterase
A6J74_RS09380	COG1266	CAAX protease self-immunity
A6J74_RS09385	COG0514	ATP-dependent DNA helicase (RecQ)
A6J74_RS09390	COG4955	Helix-turn-helix domain
A6J74_RS09395	COG1141	Ferredoxin
A6J74_RS09400	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
A6J74_RS09410	COG4942	peptidase
A6J74_RS09415	COG2096	Adenosyltransferase
A6J74_RS09420	COG5002	protein histidine kinase activity
A6J74_RS09425	COG0745	RESPONSE REGULATOR receiver
A6J74_RS09430	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A6J74_RS09435	COG1333	cytochrome c biogenesis protein
A6J74_RS09445	COG1187	pseudouridine synthase activity
A6J74_RS09450	COG0700	Nucleoside recognition
A6J74_RS09455	COG2715	membrane protein required for spore maturation
A6J74_RS09460	COG1686	Belongs to the peptidase S11 family
A6J74_RS09465	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A6J74_RS09480	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
A6J74_RS09480	COG0392	lysyltransferase activity
A6J74_RS09495	COG5002	protein histidine kinase activity
A6J74_RS09500	COG0582	viral genome integration into host DNA
A6J74_RS09510	COG1801	Protein of unknown function DUF72
A6J74_RS09515	COG3852	Histidine kinase
A6J74_RS09530	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A6J74_RS09535	COG1392	Phosphate transport regulator
A6J74_RS09540	COG0306	phosphate transporter
A6J74_RS09545	COG0730	response to heat
A6J74_RS09585	COG2226	methyltransferase
A6J74_RS09595	COG1114	Component of the transport system for branched-chain amino acids
A6J74_RS09605	COG2197	response regulator
A6J74_RS09610	COG4585	Histidine kinase
A6J74_RS09615	COG4758	membrane
A6J74_RS09630	COG1757	Na H antiporter
A6J74_RS09650	COG0733	neurotransmitter:sodium symporter activity
A6J74_RS09660	COG1648	precorrin-2 dehydrogenase activity
A6J74_RS09680	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A6J74_RS09685	COG0529	Catalyzes the synthesis of activated sulfate
A6J74_RS09705	COG0019	diaminopimelate decarboxylase activity
A6J74_RS09715	COG1368	sulfuric ester hydrolase activity
A6J74_RS09720	COG1183	phosphatidylcholine synthase activity
A6J74_RS09725	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A6J74_RS09735	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A6J74_RS09740	COG0140	phosphoribosyl-ATP diphosphatase activity
A6J74_RS09750	COG0107	imidazoleglycerol-phosphate synthase activity
A6J74_RS09760	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
A6J74_RS09790	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
A6J74_RS09810	COG0440	acetolactate synthase activity
A6J74_RS09815	COG0028	Belongs to the TPP enzyme family
A6J74_RS09820	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A6J74_RS09850	COG3874	Sporulation protein YtfJ
A6J74_RS09855	COG4709	membrane
A6J74_RS09860	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A6J74_RS09865	COG1301	dicarboxylic acid transport
A6J74_RS09875	COG1846	Transcriptional regulator
A6J74_RS09900	COG0534	Mate efflux family protein
A6J74_RS09940	COG0716	FMN binding
A6J74_RS09965	COG1696	Membrane protein involved in D-alanine export
A6J74_RS09975	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
A6J74_RS09980	COG2070	2-Nitropropane dioxygenase
A6J74_RS09985	COG1619	proteins homologs of microcin C7 resistance protein MccF
A6J74_RS09995	COG1335	isochorismatase
A6J74_RS10005	COG1522	sequence-specific DNA binding
A6J74_RS10015	COG1266	CAAX protease self-immunity
A6J74_RS10020	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
A6J74_RS10025	COG1131	(ABC) transporter
A6J74_RS10035	COG1131	(ABC) transporter
A6J74_RS10040	COG1725	Transcriptional regulator
A6J74_RS10050	COG1012	belongs to the aldehyde dehydrogenase family
A6J74_RS10055	COG2204	response regulator
A6J74_RS10070	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A6J74_RS10075	COG0531	amino acid
A6J74_RS10080	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A6J74_RS10095	COG1780	Probably involved in ribonucleotide reductase function
A6J74_RS10115	COG0456	acetyltransferase
A6J74_RS10125	COG4873	Protein conserved in bacteria
A6J74_RS10140	COG0720	synthase
A6J74_RS10150	COG5002	protein histidine kinase activity
A6J74_RS10160	COG2318	DinB family
A6J74_RS10170	COG1846	Transcriptional regulator
A6J74_RS10175	COG3852	Histidine kinase
A6J74_RS10185	COG2861	carbohydrate metabolic process
A6J74_RS10195	COG0235	Class ii aldolase
A6J74_RS10210	COG1349	DNA-binding transcription factor activity
A6J74_RS10235	COG3842	ATPase activity
A6J74_RS10240	COG1840	ABC-type Fe3 transport system, periplasmic component
A6J74_RS10260	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A6J74_RS10270	COG3243	poly(R)-hydroxyalkanoic acid synthase
A6J74_RS10275	COG1028	Short-chain dehydrogenase reductase Sdr
A6J74_RS10295	COG2030	dehydratase
A6J74_RS10305	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A6J74_RS10310	COG0861	Integral membrane protein TerC family
A6J74_RS10315	COG2116	formate transmembrane transporter activity
A6J74_RS10325	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
A6J74_RS10345	COG2186	Transcriptional regulator
A6J74_RS10350	COG5002	protein histidine kinase activity
A6J74_RS10355	COG0745	RESPONSE REGULATOR receiver
A6J74_RS10365	COG3835	regulator
A6J74_RS10370	COG0277	FAD linked oxidase domain protein
A6J74_RS10375	COG0247	lactate metabolic process
A6J74_RS10380	COG2340	Cysteine-rich secretory protein family
A6J74_RS10390	COG0564	pseudouridine synthase activity
A6J74_RS10400	COG2409	Drug exporters of the RND superfamily
A6J74_RS10410	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
A6J74_RS10415	COG1177	transmembrane transport
A6J74_RS10420	COG1176	ABC-type spermidine putrescine transport system, permease component I
A6J74_RS10430	COG1012	belongs to the aldehyde dehydrogenase family
A6J74_RS10465	COG0681	Belongs to the peptidase S26 family
A6J74_RS10470	COG1686	Belongs to the peptidase S11 family
A6J74_RS10510	COG1668	transmembrane transport
A6J74_RS10515	COG4152	abc transporter atp-binding protein
A6J74_RS10555	COG1476	TRANSCRIPTIONal
A6J74_RS10565	COG0508	dehydrogenase complex catalyzes the overall conversion of
A6J74_RS10585	COG2226	methyltransferase
A6J74_RS10660	COG5634	Uncharacterized conserved protein (DUF2278)
A6J74_RS10665	COG1620	l-lactate permease
A6J74_RS10680	COG0133	tryptophan synthase activity
A6J74_RS10695	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A6J74_RS10700	COG0512	Glutamine amidotransferase of anthranilate synthase
A6J74_RS10700	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A6J74_RS10715	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A6J74_RS10720	COG5492	domain, Protein
A6J74_RS10730	COG0697	spore germination
A6J74_RS10735	COG2382	esterase
A6J74_RS10745	COG2153	protein acetylation
A6J74_RS10790	COG1091	dTDP-4-dehydrorhamnose reductase activity
A6J74_RS10805	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
A6J74_RS10825	COG0457	Tetratricopeptide repeat
A6J74_RS10825	COG0463	Glycosyl transferase, family 2
A6J74_RS10845	COG1216	Glycosyl transferase, family 2
A6J74_RS10850	COG0772	Belongs to the SEDS family
A6J74_RS10865	COG0564	pseudouridine synthase activity
A6J74_RS10875	COG2357	RelA SpoT domain protein
A6J74_RS10885	COG4116	CYTH
A6J74_RS10890	COG2346	COG2346, Truncated hemoglobins
A6J74_RS10905	COG1164	Oligoendopeptidase f
A6J74_RS10915	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A6J74_RS10925	COG0861	Integral membrane protein TerC family
A6J74_RS10945	COG4166	transmembrane transport
A6J74_RS10950	COG0534	Mate efflux family protein
A6J74_RS10955	COG4608	Belongs to the ABC transporter superfamily
A6J74_RS10960	COG0444	Belongs to the ABC transporter superfamily
A6J74_RS10965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A6J74_RS10970	COG0601	transmembrane transport
A6J74_RS10975	COG4166	transmembrane transport
A6J74_RS10990	COG0180	Tryptophanyl-tRNA synthetase
A6J74_RS11000	COG5504	Zn-dependent protease
A6J74_RS11005	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A6J74_RS11010	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A6J74_RS11025	COG2267	carboxylic ester hydrolase activity
A6J74_RS11050	COG0561	phosphatase activity
A6J74_RS11065	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A6J74_RS11090	COG2996	Protein conserved in bacteria
A6J74_RS11115	COG0004	ammonium transporteR
A6J74_RS11120	COG0753	catalase activity
A6J74_RS11130	COG0367	asparagine synthase
A6J74_RS11155	COG0179	Fumarylacetoacetate (FAA) hydrolase
A6J74_RS11215	COG0398	Pfam SNARE associated Golgi protein
A6J74_RS11225	COG4903	ComK protein
A6J74_RS11255	COG2224	Isocitrate lyase
A6J74_RS11260	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
A6J74_RS11265	COG0697	spore germination
A6J74_RS11270	COG0840	transmembrane signaling receptor activity
A6J74_RS11275	COG0501	Belongs to the peptidase M48B family
A6J74_RS11300	COG0745	RESPONSE REGULATOR receiver
A6J74_RS11305	COG2205	protein histidine kinase activity
A6J74_RS11320	COG3708	Transcriptional regulator
A6J74_RS11320	COG2207	Transcriptional regulator
A6J74_RS11325	COG1595	DNA-templated transcription, initiation
A6J74_RS11335	COG1078	dGTPase activity
A6J74_RS11345	COG1408	metallophosphoesterase
A6J74_RS11365	COG0318	PFAM AMP-dependent synthetase and ligase
A6J74_RS11375	COG0095	Lipoate-protein ligase
A6J74_RS11380	COG1234	tRNA 3'-trailer cleavage
A6J74_RS11390	COG1609	Transcriptional regulator
A6J74_RS11435	COG1511	domain protein
A6J74_RS11440	COG1309	transcriptional regulator
A6J74_RS11470	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
A6J74_RS11485	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A6J74_RS11490	COG2329	Antibiotic biosynthesis monooxygenase
A6J74_RS11495	COG3428	Bacterial PH domain
A6J74_RS11500	COG3402	PFAM membrane-flanked domain
A6J74_RS11545	COG3428	Bacterial PH domain
A6J74_RS11550	COG3402	PFAM membrane-flanked domain
A6J74_RS11560	COG1309	transcriptional regulator
A6J74_RS11575	COG4473	ABC transporter
A6J74_RS11580	COG1131	(ABC) transporter
A6J74_RS11590	COG0537	adenosine 5'-monophosphoramidase activity
A6J74_RS11620	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A6J74_RS11625	COG3973	AAA domain
A6J74_RS11645	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
A6J74_RS11655	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A6J74_RS11660	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
A6J74_RS11665	COG3620	sequence-specific DNA binding
A6J74_RS11685	COG0457	Tetratricopeptide repeat
A6J74_RS11690	COG0346	lactoylglutathione lyase activity
A6J74_RS11695	COG0346	lactoylglutathione lyase activity
A6J74_RS11705	COG0714	Associated with various cellular activities
A6J74_RS11725	COG4717	serine-type aminopeptidase activity
A6J74_RS11730	COG0420	3'-5' exonuclease activity
A6J74_RS11765	COG2186	Transcriptional regulator
A6J74_RS11770	COG2807	transmembrane transport
A6J74_RS11800	COG0784	Response regulator, receiver
A6J74_RS11800	COG2198	Histidine kinase
A6J74_RS11800	COG2205	protein histidine kinase activity
A6J74_RS11805	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
A6J74_RS11810	COG2208	phosphoserine phosphatase activity
A6J74_RS11825	COG1191	sigma factor activity
A6J74_RS11850	COG3237	CsbD-like
A6J74_RS11890	COG3850	Histidine kinase
A6J74_RS11890	COG5002	protein histidine kinase activity
A6J74_RS11895	COG0745	RESPONSE REGULATOR receiver
A6J74_RS11910	COG1959	2 iron, 2 sulfur cluster binding
A6J74_RS11920	COG2376	Dihydroxyacetone kinase
A6J74_RS11935	COG2376	Dihydroxyacetone kinase
A6J74_RS11950	COG0640	Transcriptional regulator
A6J74_RS11955	COG2814	Major facilitator Superfamily
A6J74_RS11980	COG1183	phosphatidylcholine synthase activity
A6J74_RS11990	COG2723	6-phospho-beta-galactosidase activity
A6J74_RS11995	COG2190	(PTS) system
A6J74_RS11995	COG1263	PTS System
A6J74_RS11995	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A6J74_RS12000	COG3711	transcriptional antiterminator
A6J74_RS12010	COG3409	Peptidoglycan-binding domain 1 protein
A6J74_RS12010	COG5632	N-Acetylmuramoyl-L-alanine amidase
A6J74_RS12050	COG0477	Major facilitator Superfamily
A6J74_RS12070	COG1012	belongs to the aldehyde dehydrogenase family
A6J74_RS12075	COG0305	Participates in initiation and elongation during chromosome replication
A6J74_RS12125	COG0582	viral genome integration into host DNA
A6J74_RS12135	COG3181	Tripartite tricarboxylate transporter family receptor
A6J74_RS12140	COG4565	transcriptional regulatory protein
A6J74_RS12145	COG3290	protein histidine kinase activity
A6J74_RS12150	COG0477	Major facilitator Superfamily
A6J74_RS12200	COG0582	viral genome integration into host DNA
A6J74_RS12265	COG0457	Tetratricopeptide repeat
A6J74_RS12285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A6J74_RS12295	COG4608	Belongs to the ABC transporter superfamily
A6J74_RS12300	COG0444	Belongs to the ABC transporter superfamily
A6J74_RS12305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A6J74_RS12310	COG0601	transmembrane transport
A6J74_RS12335	COG0579	oxidoreductase
A6J74_RS12365	COG1363	Peptidase, m42
A6J74_RS12385	COG1024	Enoyl-CoA hydratase
A6J74_RS12395	COG0659	secondary active sulfate transmembrane transporter activity
A6J74_RS12410	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A6J74_RS12420	COG0561	phosphatase activity
A6J74_RS12435	COG3527	Alpha-acetolactate decarboxylase
A6J74_RS12440	COG0028	Belongs to the TPP enzyme family
A6J74_RS12460	COG0189	ligase activity
A6J74_RS12475	COG1126	abc transporter atp-binding protein
A6J74_RS12480	COG0765	amino acid transport
A6J74_RS12485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6J74_RS12495	COG1132	(ABC) transporter
A6J74_RS12500	COG1132	(ABC) transporter
A6J74_RS12515	COG1012	belongs to the aldehyde dehydrogenase family
A6J74_RS12520	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
A6J74_RS12525	COG0531	amino acid
A6J74_RS12535	COG0693	protein deglycase activity
A6J74_RS12545	COG2211	Major facilitator Superfamily
A6J74_RS12550	COG4533	DNA binding
A6J74_RS12560	COG2249	NAD(P)H dehydrogenase (quinone) activity
A6J74_RS12570	COG1733	regulation of RNA biosynthetic process
A6J74_RS12575	COG2814	Major facilitator Superfamily
A6J74_RS12580	COG1309	transcriptional regulator
A6J74_RS12585	COG2076	Multidrug Resistance protein
A6J74_RS12620	COG1522	sequence-specific DNA binding
A6J74_RS12640	COG2259	Doxx family
A6J74_RS12650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A6J74_RS12650	COG1263	PTS System
A6J74_RS12660	COG1737	Transcriptional regulator
A6J74_RS12670	COG0475	glutathione-regulated potassium exporter activity
A6J74_RS12675	COG0531	amino acid
A6J74_RS12710	COG0586	Pfam SNARE associated Golgi protein
A6J74_RS12745	COG3546	catalase activity
A6J74_RS12750	COG1114	Component of the transport system for branched-chain amino acids
A6J74_RS12765	COG5522	Integral membrane protein (intg_mem_TP0381)
A6J74_RS12775	COG1136	(ABC) transporter
A6J74_RS12780	COG0577	efflux transmembrane transporter activity
A6J74_RS12785	COG1388	LysM domain
A6J74_RS12785	COG3584	3D domain protein
A6J74_RS12805	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A6J74_RS12810	COG1447	Phosphotransferase system cellobiose-specific component IIA
A6J74_RS12815	COG3711	transcriptional antiterminator
A6J74_RS12815	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A6J74_RS12830	COG2814	Major facilitator Superfamily
A6J74_RS12835	COG1283	sodium-dependent phosphate transmembrane transporter activity
A6J74_RS12840	COG0604	alcohol dehydrogenase
A6J74_RS12845	COG1316	TRANSCRIPTIONal
A6J74_RS12855	COG0730	response to heat
A6J74_RS12860	COG2210	Belongs to the sulfur carrier protein TusA family
A6J74_RS12865	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A6J74_RS12870	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A6J74_RS12870	COG0425	Belongs to the sulfur carrier protein TusA family
A6J74_RS12875	COG0425	Belongs to the sulfur carrier protein TusA family
A6J74_RS12880	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A6J74_RS12880	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A6J74_RS12885	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A6J74_RS12885	COG0425	Belongs to the sulfur carrier protein TusA family
A6J74_RS12890	COG1937	Protein conserved in bacteria
A6J74_RS12895	COG0446	pyridine nucleotide-disulphide oxidoreductase
A6J74_RS12910	COG2719	SpoVR family
A6J74_RS12915	COG0778	Nitroreductase
A6J74_RS12975	COG1028	Short-chain dehydrogenase reductase Sdr
A6J74_RS12980	COG2252	PERMEase
A6J74_RS12990	COG1129	ABC transporter
A6J74_RS12995	COG1172	Belongs to the binding-protein-dependent transport system permease family
A6J74_RS13010	COG1846	Transcriptional regulator
A6J74_RS13015	COG2814	Major facilitator Superfamily
A6J74_RS13020	COG2205	protein histidine kinase activity
A6J74_RS13025	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
A6J74_RS13030	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
A6J74_RS13035	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
A6J74_RS13060	COG0351	phosphomethylpyrimidine kinase
A6J74_RS13065	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A6J74_RS13070	COG2022	thiamine diphosphate biosynthetic process
A6J74_RS13075	COG2104	thiamine diphosphate biosynthetic process
A6J74_RS13080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A6J74_RS13085	COG0352	thiamine-phosphate diphosphorylase activity
A6J74_RS13090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A6J74_RS13095	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A6J74_RS13100	COG1116	anion transmembrane transporter activity
A6J74_RS13105	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
A6J74_RS13130	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
A6J74_RS13250	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A6J74_RS13260	COG0581	inorganic phosphate transmembrane transporter activity
A6J74_RS13265	COG0573	inorganic phosphate transmembrane transporter activity
A6J74_RS13270	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A6J74_RS13275	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
A6J74_RS13275	COG1918	ferrous iron import across plasma membrane
A6J74_RS13280	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
A6J74_RS13285	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
A6J74_RS13300	COG0531	amino acid
A6J74_RS13305	COG0697	spore germination
A6J74_RS13310	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A6J74_RS13325	COG4990	cell redox homeostasis
A6J74_RS13330	COG0833	amino acid
A6J74_RS13335	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
A6J74_RS13340	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A6J74_RS13345	COG1845	cytochrome c oxidase, subunit III
A6J74_RS13355	COG0569	domain protein
A6J74_RS13355	COG0475	glutathione-regulated potassium exporter activity
A6J74_RS13380	COG2252	PERMEase
A6J74_RS13385	COG1113	amino acid transport
A6J74_RS13400	COG1114	Component of the transport system for branched-chain amino acids
A6J74_RS13405	COG3104	oligopeptide transport
A6J74_RS13425	COG1476	TRANSCRIPTIONal
A6J74_RS13430	COG3584	3D domain protein
A6J74_RS13430	COG1388	LysM domain
A6J74_RS13435	COG0840	transmembrane signaling receptor activity
A6J74_RS13485	COG1063	alcohol dehydrogenase
A6J74_RS13515	COG1879	ABC-type sugar transport system periplasmic component
A6J74_RS13520	COG1172	Belongs to the binding-protein-dependent transport system permease family
A6J74_RS13535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A6J74_RS13540	COG1609	Transcriptional regulator
A6J74_RS13545	COG0477	Major facilitator Superfamily
A6J74_RS13550	COG1846	Transcriptional regulator
A6J74_RS13555	COG2271	Major facilitator Superfamily
A6J74_RS13570	COG0659	secondary active sulfate transmembrane transporter activity
A6J74_RS13585	COG5002	protein histidine kinase activity
A6J74_RS13590	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A6J74_RS13595	COG2378	regulation of single-species biofilm formation
A6J74_RS13605	COG1595	DNA-templated transcription, initiation
A6J74_RS13620	COG0833	amino acid
A6J74_RS13625	COG0765	amino acid transport
A6J74_RS13630	COG0765	amino acid transport
A6J74_RS13635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6J74_RS13640	COG1126	abc transporter atp-binding protein
A6J74_RS13645	COG1115	amino acid carrier protein
A6J74_RS13650	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A6J74_RS13660	COG1404	Belongs to the peptidase S8 family
A6J74_RS13665	COG2197	response regulator
A6J74_RS13670	COG4585	Histidine kinase
A6J74_RS13675	COG0697	spore germination
A6J74_RS13690	COG0366	Alpha amylase catalytic
A6J74_RS13695	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A6J74_RS13695	COG1263	PTS System
A6J74_RS13700	COG2188	Transcriptional regulator
A6J74_RS13705	COG0531	amino acid
A6J74_RS13725	COG0714	Associated with various cellular activities
A6J74_RS13730	COG4548	von Willebrand factor, type A
A6J74_RS13740	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A6J74_RS13750	COG2226	methyltransferase
A6J74_RS13760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A6J74_RS13765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A6J74_RS13770	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A6J74_RS13775	COG3104	oligopeptide transport
A6J74_RS13790	COG1620	l-lactate permease
A6J74_RS13795	COG1027	Aspartate ammonia-lyase
A6J74_RS13800	COG1253	flavin adenine dinucleotide binding
A6J74_RS13805	COG0346	lactoylglutathione lyase activity
A6J74_RS13810	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A6J74_RS13815	COG1316	TRANSCRIPTIONal
A6J74_RS13820	COG2720	vancomycin resistance protein
A6J74_RS13840	COG3227	Zinc metalloprotease (Elastase)
A6J74_RS13850	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
A6J74_RS13855	COG2217	Heavy metal translocating P-type atpase
A6J74_RS13860	COG0640	Transcriptional regulator
A6J74_RS13875	COG0531	amino acid
A6J74_RS13890	COG2427	Protein of unknown function (DUF1641)
A6J74_RS13895	COG3383	formate dehydrogenase (NAD+) activity
A6J74_RS13900	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
A6J74_RS13905	COG0454	-acetyltransferase
A6J74_RS13905	COG0456	acetyltransferase
A6J74_RS13915	COG0745	RESPONSE REGULATOR receiver
A6J74_RS13920	COG5002	protein histidine kinase activity
A6J74_RS13935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A6J74_RS13940	COG0697	spore germination
A6J74_RS13950	COG0281	malic enzyme
A6J74_RS13955	COG3493	citrate carrier protein
A6J74_RS13960	COG4565	transcriptional regulatory protein
A6J74_RS13965	COG3290	protein histidine kinase activity
A6J74_RS13975	COG4990	cell redox homeostasis
A6J74_RS13985	COG5002	protein histidine kinase activity
A6J74_RS13990	COG0745	RESPONSE REGULATOR receiver
A6J74_RS13995	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
A6J74_RS14005	COG0395	ABC-type sugar transport system, permease component
A6J74_RS14010	COG1175	transmembrane transport
A6J74_RS14015	COG3842	ATPase activity
A6J74_RS14020	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
A6J74_RS14045	COG2851	Citrate transporter
A6J74_RS14050	COG4565	transcriptional regulatory protein
A6J74_RS14055	COG3290	protein histidine kinase activity
A6J74_RS14065	COG2268	Band 7 protein
A6J74_RS14070	COG1585	Membrane protein implicated in regulation of membrane protease activity
A6J74_RS14085	COG2718	Belongs to the UPF0229 family
A6J74_RS14100	COG2766	serine protein kinase
A6J74_RS14110	COG5001	Diguanylate cyclase
A6J74_RS14110	COG1716	ATPase activity
A6J74_RS14115	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
A6J74_RS14140	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
A6J74_RS14265	COG0735	belongs to the Fur family
A6J74_RS14270	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A6J74_RS14290	COG4555	ABC transporter
A6J74_RS14295	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
A6J74_RS14300	COG0067	glutamate synthase
A6J74_RS14300	COG0070	glutamate synthase
A6J74_RS14300	COG0069	glutamate synthase activity
A6J74_RS14305	COG4129	membrane
A6J74_RS14310	COG1132	(ABC) transporter
A6J74_RS14315	COG3557	Belongs to the UPF0374 family
A6J74_RS14335	COG1194	a g-specific adenine glycosylase
A6J74_RS14340	COG1988	membrane-bound metal-dependent
A6J74_RS14370	COG1090	epimerase
A6J74_RS14375	COG1228	amidohydrolase
A6J74_RS14395	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A6J74_RS14400	COG1882	Formate acetyltransferase
A6J74_RS14410	COG0463	Glycosyl transferase, family 2
A6J74_RS14415	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A6J74_RS14415	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
A6J74_RS14425	COG0463	Glycosyl transferase, family 2
A6J74_RS14445	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A6J74_RS14450	COG1263	PTS System
A6J74_RS14450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A6J74_RS14480	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A6J74_RS14485	COG0833	amino acid
A6J74_RS14495	COG3829	transcription factor binding
A6J74_RS14515	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
A6J74_RS14535	COG0535	radical SAM domain protein
A6J74_RS14545	COG0387	Pfam Sodium calcium exchanger
A6J74_RS14550	COG3871	stress protein (general stress protein 26)
A6J74_RS14565	COG0586	Pfam SNARE associated Golgi protein
A6J74_RS14585	COG0697	spore germination
A6J74_RS14590	COG2217	Heavy metal translocating P-type atpase
A6J74_RS14600	COG1295	ribonuclease BN
A6J74_RS14610	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A6J74_RS14625	COG3853	Toxic anion resistance protein (TelA)
A6J74_RS14635	COG0861	Integral membrane protein TerC family
A6J74_RS14640	COG2310	stress, protein
A6J74_RS14645	COG2310	stress, protein
A6J74_RS14650	COG2310	stress, protein
A6J74_RS14660	COG4193	domain, Protein
A6J74_RS14660	COG4193	domain, Protein
A6J74_RS14685	COG2270	Major facilitator Superfamily
A6J74_RS14735	COG1116	anion transmembrane transporter activity
A6J74_RS14745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A6J74_RS14765	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
A6J74_RS14770	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A6J74_RS14800	COG2190	(PTS) system
A6J74_RS14800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A6J74_RS14800	COG1263	PTS System
A6J74_RS14805	COG0366	Alpha amylase catalytic
A6J74_RS14810	COG0277	FAD linked oxidase domain protein
A6J74_RS14825	COG0549	Belongs to the carbamate kinase family
A6J74_RS14850	COG0840	transmembrane signaling receptor activity
A6J74_RS14860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6J74_RS14865	COG0765	amino acid transport
A6J74_RS14875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A6J74_RS14875	COG0723	plastoquinol--plastocyanin reductase activity
A6J74_RS14880	COG2814	Major facilitator Superfamily
A6J74_RS14885	COG3541	Predicted nucleotidyltransferase
A6J74_RS14905	COG5002	protein histidine kinase activity
A6J74_RS14930	COG0166	Belongs to the GPI family
A6J74_RS14940	COG0492	ferredoxin-NADP+ reductase activity
A6J74_RS14950	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A6J74_RS14955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A6J74_RS14960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A6J74_RS14980	COG0450	alkyl hydroperoxide reductase
A6J74_RS14995	COG1473	amidohydrolase
A6J74_RS15000	COG1757	Na H antiporter
A6J74_RS15025	COG4807	Protein conserved in bacteria
A6J74_RS15035	COG5002	protein histidine kinase activity
A6J74_RS15040	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A6J74_RS15050	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A6J74_RS15065	COG2309	aminopeptidase activity
A6J74_RS15075	COG2076	Multidrug Resistance protein
A6J74_RS15080	COG1012	belongs to the aldehyde dehydrogenase family
A6J74_RS15090	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A6J74_RS15095	COG0546	phosphoglycolate phosphatase activity
A6J74_RS15100	COG1597	lipid kinase activity
A6J74_RS15120	COG4682	membrane
A6J74_RS15125	COG1846	Transcriptional regulator
A6J74_RS15130	COG0003	Pfam Anion-transporting ATPase
A6J74_RS15145	COG1464	Belongs to the NlpA lipoprotein family
A6J74_RS15150	COG2011	ABC-type metal ion transport system permease component
A6J74_RS15160	COG1335	isochorismatase
A6J74_RS15175	COG4851	CamS sex pheromone cAM373 precursor
A6J74_RS15185	COG0210	DNA helicase
A6J74_RS15210	COG0151	Belongs to the GarS family
A6J74_RS15215	COG0138	bifunctional purine biosynthesis protein purh
A6J74_RS15220	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
A6J74_RS15230	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
A6J74_RS15245	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A6J74_RS15255	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A6J74_RS15260	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
A6J74_RS15265	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A6J74_RS15290	COG0745	RESPONSE REGULATOR receiver
A6J74_RS15295	COG2205	protein histidine kinase activity
A6J74_RS15345	COG0697	spore germination
A6J74_RS15365	COG1215	transferase activity, transferring glycosyl groups
A6J74_RS15375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A6J74_RS15415	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
A6J74_RS15440	COG5002	protein histidine kinase activity
A6J74_RS15450	COG2252	PERMEase
A6J74_RS15465	COG0459	protein refolding
A6J74_RS15475	COG1266	CAAX protease self-immunity
A6J74_RS15490	COG0488	(ABC) transporter
A6J74_RS15500	COG0456	acetyltransferase
A6J74_RS15505	COG1214	PFAM Peptidase M22, glycoprotease
A6J74_RS15510	COG0802	atpase or kinase
A6J74_RS15610	COG2183	response to ionizing radiation
A6J74_RS15615	COG2337	Toxic component of a toxin-antitoxin (TA) module
A6J74_RS15620	COG0864	Transcriptional regulator
A6J74_RS15625	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A6J74_RS15630	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
A6J74_RS15640	COG0705	Rhomboid family
A6J74_RS15645	COG4294	response to UV
A6J74_RS15655	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A6J74_RS15665	COG2814	Major facilitator Superfamily
A6J74_RS15670	COG0531	amino acid
A6J74_RS15680	COG0179	Fumarylacetoacetate (FAA) hydrolase
A6J74_RS15685	COG3185	4-Hydroxyphenylpyruvate dioxygenase
A6J74_RS15715	COG0561	phosphatase activity
A6J74_RS15720	COG4608	Belongs to the ABC transporter superfamily
A6J74_RS15725	COG0444	Belongs to the ABC transporter superfamily
A6J74_RS15730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A6J74_RS15735	COG0601	transmembrane transport
A6J74_RS15740	COG0747	negative chemotaxis
A6J74_RS15750	COG0488	(ABC) transporter
A6J74_RS15775	COG5298	Protein conserved in bacteria
A6J74_RS15795	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A6J74_RS15805	COG1609	Transcriptional regulator
A6J74_RS15820	COG0204	Acyl-transferase
A6J74_RS15840	COG0697	spore germination
A6J74_RS15860	COG1910	domain protein
A6J74_RS15865	COG0725	ABC transporter, periplasmic molybdate-binding protein
A6J74_RS15870	COG4149	molybdate abc transporter
A6J74_RS15890	COG0656	L-ascorbic acid biosynthetic process
A6J74_RS15895	COG4166	transmembrane transport
A6J74_RS15900	COG4166	transmembrane transport
A6J74_RS15915	COG2207	Transcriptional regulator
A6J74_RS15925	COG4166	transmembrane transport
A6J74_RS15930	COG4608	Belongs to the ABC transporter superfamily
A6J74_RS15935	COG0444	Belongs to the ABC transporter superfamily
A6J74_RS15940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A6J74_RS15945	COG0601	transmembrane transport
A6J74_RS15960	COG2814	Major facilitator Superfamily
A6J74_RS15970	COG2271	Major facilitator Superfamily
A6J74_RS15975	COG0277	FAD linked oxidase domain protein
A6J74_RS15985	COG0604	alcohol dehydrogenase
A6J74_RS15990	COG1464	Belongs to the NlpA lipoprotein family
A6J74_RS16000	COG2011	ABC-type metal ion transport system permease component
A6J74_RS16005	COG1028	Short-chain dehydrogenase reductase Sdr
A6J74_RS16045	COG4856	YbbR-like protein
A6J74_RS16050	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
A6J74_RS16135	COG0726	polysaccharide deacetylase
A6J74_RS16140	COG2194	sulfuric ester hydrolase activity
A6J74_RS16150	COG0489	protein tyrosine kinase activity
A6J74_RS16155	COG0860	N-Acetylmuramoyl-L-alanine amidase
A6J74_RS16180	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A6J74_RS16215	COG0257	Belongs to the bacterial ribosomal protein bL36 family
A6J74_RS16225	COG0024	Methionine aminopeptidase
A6J74_RS16235	COG0201	protein transport
A6J74_RS16245	COG1841	ribosomal large subunit assembly
A6J74_RS16295	COG0255	Belongs to the universal ribosomal protein uL29 family
A6J74_RS16335	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
A6J74_RS16340	COG0051	transcription antitermination factor activity, RNA binding
A6J74_RS16360	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
A6J74_RS16365	COG1358	cellular component organization or biogenesis
A6J74_RS16380	COG2813	Specifically methylates the guanine in position
A6J74_RS16385	COG0222	ribosome binding
A6J74_RS16395	COG0081	regulation of translation
A6J74_RS16400	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
A6J74_RS16405	COG0250	Participates in transcription elongation, termination and antitermination
A6J74_RS16410	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A6J74_RS16415	COG0267	Belongs to the bacterial ribosomal protein bL33 family
A6J74_RS16425	COG3688	RNA-binding protein containing a PIN domain
A6J74_RS16430	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A6J74_RS16445	COG1045	serine acetyltransferase
A6J74_RS16465	COG4956	integral membrane protein (PIN domain superfamily)
A6J74_RS16475	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
A6J74_RS16480	COG0542	response to heat
A6J74_RS16490	COG3880	PFAM UvrB UvrC protein
A6J74_RS16585	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A6J74_RS16590	COG1396	sequence-specific DNA binding
A6J74_RS16595	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A6J74_RS16600	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
A6J74_RS16605	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A6J74_RS16610	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A6J74_RS16615	COG0512	Glutamine amidotransferase of anthranilate synthase
A6J74_RS16620	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A6J74_RS16625	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A6J74_RS16640	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A6J74_RS16645	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
A6J74_RS16655	COG2208	phosphoserine phosphatase activity
A6J74_RS16670	COG1098	S1 RNA binding domain
A6J74_RS16690	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A6J74_RS16695	COG3956	TIGRFAM MazG family protein
A6J74_RS16700	COG2244	polysaccharide biosynthetic process
A6J74_RS16705	COG2002	toxin-antitoxin pair type II binding
A6J74_RS16710	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A6J74_RS16735	COG2088	sporulation resulting in formation of a cellular spore
A6J74_RS16740	COG0251	oxidation-reduction process
A6J74_RS16750	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A6J74_RS16765	COG4466	Protein conserved in bacteria
A6J74_RS16775	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
A6J74_RS16785	COG0084	hydrolase, TatD family'
A6J74_RS16795	COG2002	toxin-antitoxin pair type II binding
A6J74_RS16800	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
A6J74_RS16810	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
A6J74_RS16820	COG1774	PSP1 C-terminal conserved region
A6J74_RS16825	COG0470	DNA polymerase III
A6J74_RS16835	COG1982	Orn Lys Arg decarboxylase major
A6J74_RS16890	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A6J74_RS16900	COG0590	tRNA wobble adenosine to inosine editing
A6J74_RS16910	COG1335	isochorismatase
A6J74_RS16915	COG1428	Deoxynucleoside kinase
A6J74_RS16920	COG1428	Deoxynucleoside kinase
A6J74_RS16950	COG1686	Belongs to the peptidase S11 family
A6J74_RS16955	COG0516	GMP reductase activity
A6J74_RS16955	COG0517	IMP dehydrogenase activity
A6J74_RS16990	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A6J74_RS16995	COG0187	DNA topoisomerase II activity
A6J74_RS17005	COG2501	S4 domain
A6J74_RS17010	COG0592	DNA-directed DNA polymerase activity
A6J74_RS17020	COG0230	Belongs to the bacterial ribosomal protein bL34 family
A6J74_RS17030	COG0706	membrane insertase activity
A6J74_RS17035	COG1847	R3H domain protein
A6J74_RS17060	COG1192	Involved in chromosome partitioning
A6J74_RS17065	COG1475	DNA binding
A6J74_RS17075	COG0668	transmembrane transport
A6J74_RS17080	COG4481	Protein conserved in bacteria
A6J74_RS17085	COG0012	GTP binding
A6J74_RS17095	COG0629	single-stranded DNA binding
A6J74_RS17105	COG4241	membrane
A6J74_RS17110	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
A6J74_RS17120	COG0305	Participates in initiation and elongation during chromosome replication
A6J74_RS17150	COG0745	RESPONSE REGULATOR receiver
A6J74_RS17155	COG5002	protein histidine kinase activity
A6J74_RS17165	COG4853	Protein conserved in bacteria
A6J74_RS17170	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A6J74_RS17175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A6J74_RS17195	COG1164	Oligoendopeptidase f
A6J74_RS17220	COG1272	protein, Hemolysin III
A6J74_RS17225	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A6J74_RS17260	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
A6J74_RS17265	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A6J74_RS17270	COG2814	Major facilitator Superfamily
A6J74_RS17275	COG3275	phosphorelay sensor kinase activity
A6J74_RS17295	COG0628	permease
A6J74_RS17300	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A6J74_RS17300	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A6J74_RS17305	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A6J74_RS17310	COG1309	transcriptional regulator
A6J74_RS17315	COG0463	Glycosyl transferase, family 2
A6J74_RS17335	COG0488	(ABC) transporter
A6J74_RS17340	COG1309	transcriptional regulator
A6J74_RS17350	COG1215	transferase activity, transferring glycosyl groups
A6J74_RS17360	COG1607	acyl-coa hydrolase
A6J74_RS17370	COG0840	transmembrane signaling receptor activity
A6J74_RS17385	COG0438	transferase activity, transferring glycosyl groups
A6J74_RS17400	COG0477	Major facilitator Superfamily
A6J74_RS17405	COG3279	Response regulator of the LytR AlgR family
A6J74_RS17410	COG1966	Carbon starvation protein
A6J74_RS17415	COG2879	small protein
A6J74_RS17420	COG3706	GGDEF domain
A6J74_RS17425	COG0351	phosphomethylpyrimidine kinase
A6J74_RS17430	COG4585	Histidine kinase
A6J74_RS17430	COG2203	Gaf domain
A6J74_RS17435	COG2197	response regulator
A6J74_RS17445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A6J74_RS17450	COG1011	Hydrolase
A6J74_RS17460	COG2873	o-acetylhomoserine
A6J74_RS17470	COG0460	homoserine dehydrogenase
A6J74_RS17480	COG1609	Transcriptional regulator
A6J74_RS17485	COG2755	lipolytic protein G-D-S-L family
A6J74_RS17490	COG1131	(ABC) transporter
A6J74_RS17495	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
A6J74_RS17505	COG2814	Major facilitator Superfamily
A6J74_RS17510	COG0561	phosphatase activity
A6J74_RS17515	COG2233	PERMEase
A6J74_RS17520	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A6J74_RS17530	COG2363	Small membrane protein
A6J74_RS17540	COG3773	Cell wall hydrolase
A6J74_RS17560	COG0280	phosphate acetyltransferase
A6J74_RS17575	COG4844	belongs to the
A6J74_RS17580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A6J74_RS17585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A6J74_RS17590	COG1120	ATPase activity
A6J74_RS17595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A6J74_RS17600	COG1078	dGTPase activity
A6J74_RS17610	COG1994	Peptidase M50
A6J74_RS17620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A6J74_RS17625	COG0584	glycerophosphoryl diester phosphodiesterase
A6J74_RS17630	COG0789	Transcriptional regulator
A6J74_RS17635	COG2814	Major facilitator Superfamily
A6J74_RS17640	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
A6J74_RS17665	COG1619	proteins homologs of microcin C7 resistance protein MccF
A6J74_RS17670	COG4506	Protein conserved in bacteria
A6J74_RS17685	COG2234	aminopeptidase activity
A6J74_RS17690	COG0024	Methionine aminopeptidase
A6J74_RS17695	COG1131	(ABC) transporter
A6J74_RS17700	COG0842	Transport permease protein
A6J74_RS17705	COG4585	Histidine kinase
A6J74_RS17710	COG2197	response regulator
A6J74_RS17715	COG3227	Zinc metalloprotease (Elastase)
A6J74_RS17730	COG3300	MHYT domain
A6J74_RS17730	COG5001	Diguanylate cyclase
A6J74_RS17740	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A6J74_RS17750	COG0247	lactate metabolic process
A6J74_RS17750	COG2181	nitrate reductase activity
A6J74_RS17760	COG1250	3-hydroxyacyl-CoA dehydrogenase
A6J74_RS17765	COG1960	acyl-CoA dehydrogenase activity
A6J74_RS17770	COG1960	acyl-CoA dehydrogenase activity
A6J74_RS17785	COG0504	CTP synthase activity
A6J74_RS17790	COG4821	SIS domain
A6J74_RS17815	COG1494	fructose-1,6-bisphosphatase
A6J74_RS17820	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
A6J74_RS17835	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
A6J74_RS17855	COG0009	L-threonylcarbamoyladenylate synthase
A6J74_RS17875	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A6J74_RS17880	COG2259	Doxx family
A6J74_RS17885	COG2190	(PTS) system
A6J74_RS17895	COG0698	ribose 5-phosphate isomerase
A6J74_RS17930	COG0356	it plays a direct role in the translocation of protons across the membrane
A6J74_RS17950	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
A6J74_RS17995	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A6J74_RS18015	COG0839	Belongs to the complex I subunit 6 family
A6J74_RS18025	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A6J74_RS18030	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A6J74_RS18035	COG1007	ATP synthesis coupled electron transport
A6J74_RS18040	COG4836	Membrane
A6J74_RS18055	COG2385	sporulation resulting in formation of a cellular spore
A6J74_RS18060	COG3279	Response regulator of the LytR AlgR family
A6J74_RS18075	COG0739	heme binding
A6J74_RS18085	COG1609	Transcriptional regulator
A6J74_RS18100	COG0489	protein tyrosine kinase activity
A6J74_RS18105	COG3944	biosynthesis protein
A6J74_RS18110	COG0489	protein tyrosine kinase activity
A6J74_RS18115	COG4464	protein tyrosine phosphatase activity
A6J74_RS18120	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A6J74_RS18125	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A6J74_RS18180	COG0438	transferase activity, transferring glycosyl groups
A6J74_RS18185	COG0438	transferase activity, transferring glycosyl groups
A6J74_RS18195	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
A6J74_RS18210	COG1091	dTDP-4-dehydrorhamnose reductase activity
A6J74_RS18225	COG3475	LICD family
A6J74_RS18235	COG0697	spore germination
A6J74_RS18240	COG4750	Nucleotidyl transferase
A6J74_RS18245	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A6J74_RS18250	COG0745	RESPONSE REGULATOR receiver
A6J74_RS18255	COG5002	protein histidine kinase activity
A6J74_RS18255	COG3850	Histidine kinase
A6J74_RS18270	COG2271	Major facilitator Superfamily
A6J74_RS18280	COG1136	(ABC) transporter
A6J74_RS18285	COG0577	efflux transmembrane transporter activity
A6J74_RS18325	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A6J74_RS18330	COG4715	Zinc finger, swim domain protein
A6J74_RS18340	COG3584	3D domain protein
A6J74_RS18340	COG1388	LysM domain
A6J74_RS18350	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A6J74_RS18360	COG1215	transferase activity, transferring glycosyl groups
A6J74_RS18370	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A6J74_RS18375	COG1388	LysM domain
A6J74_RS18375	COG0791	NLP P60 protein
A6J74_RS18385	COG1368	sulfuric ester hydrolase activity
A6J74_RS18400	COG2389	metal-binding protein
A6J74_RS18410	COG1620	l-lactate permease
A6J74_RS18420	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A6J74_RS18425	COG1294	oxidase, subunit
A6J74_RS18430	COG1271	oxidase subunit
A6J74_RS18435	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
A6J74_RS18440	COG0583	DNA-binding transcription factor activity
A6J74_RS18445	COG1511	domain protein
A6J74_RS18450	COG0346	lactoylglutathione lyase activity
A6J74_RS18460	COG1301	dicarboxylic acid transport
A6J74_RS18465	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A6J74_RS18475	COG1447	Phosphotransferase system cellobiose-specific component IIA
A6J74_RS18485	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
A6J74_RS18485	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
A6J74_RS18495	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A6J74_RS18500	COG1447	Phosphotransferase system cellobiose-specific component IIA
A6J74_RS18505	COG1486	melibiose metabolic process
A6J74_RS18525	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
A6J74_RS18525	COG3933	PFAM sigma-54 factor interaction domain-containing protein
A6J74_RS18535	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A6J74_RS18540	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
A6J74_RS18545	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
A6J74_RS18550	COG1316	TRANSCRIPTIONal
A6J74_RS18555	COG1739	Uncharacterized protein family UPF0029
A6J74_RS18560	COG1307	EDD domain protein, DegV family
A6J74_RS18570	COG1733	regulation of RNA biosynthetic process
A6J74_RS18575	COG0791	NLP P60 protein
A6J74_RS18575	COG1388	LysM domain
A6J74_RS18580	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
A6J74_RS18585	COG1040	competence protein
A6J74_RS18590	COG1278	Cold shock
A6J74_RS18595	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
A6J74_RS18615	COG2884	Cell division ATP-binding protein ftsE
A6J74_RS18620	COG2177	Part of the ABC transporter FtsEX involved in
A6J74_RS18625	COG3409	Peptidoglycan-binding domain 1 protein
A6J74_RS18625	COG0793	Belongs to the peptidase S41A family
A6J74_RS18630	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A6J74_RS18635	COG1132	(ABC) transporter
A6J74_RS18645	COG0488	(ABC) transporter
A6J74_RS18650	COG0655	NAD(P)H dehydrogenase (quinone) activity
A6J74_RS18660	COG0583	DNA-binding transcription factor activity
A6J74_RS18680	COG0789	Transcriptional regulator
A6J74_RS18690	COG0556	nucleotide-excision repair
A6J74_RS18695	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A6J74_RS18705	COG1950	PFAM Membrane protein of
A6J74_RS18725	COG0110	maltose O-acetyltransferase activity
A6J74_RS18730	COG0457	Tetratricopeptide repeat
A6J74_RS18735	COG0492	ferredoxin-NADP+ reductase activity
A6J74_RS18745	COG1051	belongs to the nudix hydrolase family
A6J74_RS18755	COG0391	Required for morphogenesis under gluconeogenic growth conditions
A6J74_RS18765	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A6J74_RS18775	COG2323	membrane
A6J74_RS18790	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A6J74_RS18825	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
A6J74_RS18840	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A6J74_RS18875	COG1346	cytolysis
A6J74_RS18880	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A6J74_RS18885	COG1647	Serine aminopeptidase, S33
A6J74_RS18890	COG0557	exoribonuclease II activity
A6J74_RS18940	COG2233	PERMEase
A6J74_RS18945	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
A6J74_RS18950	COG0288	reversible hydration of carbon dioxide
A6J74_RS18955	COG1522	sequence-specific DNA binding
A6J74_RS18970	COG1335	isochorismatase
A6J74_RS18985	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A6J74_RS18990	COG0488	(ABC) transporter
A6J74_RS19015	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A6J74_RS19025	COG0840	transmembrane signaling receptor activity
A6J74_RS19025	COG3290	protein histidine kinase activity
A6J74_RS19040	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
A6J74_RS19045	COG1252	NADH dehydrogenase
A6J74_RS19055	COG1733	regulation of RNA biosynthetic process
A6J74_RS19060	COG2814	Major facilitator Superfamily
A6J74_RS19070	COG0656	L-ascorbic acid biosynthetic process
A6J74_RS19085	COG2910	NAD(P)H-binding
A6J74_RS19090	COG1115	amino acid carrier protein
A6J74_RS19095	COG1115	amino acid carrier protein
A6J74_RS19100	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A6J74_RS19105	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A6J74_RS19110	COG2311	Membrane
A6J74_RS19115	COG1528	Iron-storage protein
A6J74_RS19125	COG1611	Belongs to the LOG family
A6J74_RS19145	COG0783	Belongs to the Dps family
A6J74_RS19150	COG1115	amino acid carrier protein
A6J74_RS19160	COG0490	domain, Protein
A6J74_RS19165	COG0475	glutathione-regulated potassium exporter activity
A6J74_RS19170	COG0586	Pfam SNARE associated Golgi protein
A6J74_RS19190	COG3227	Zinc metalloprotease (Elastase)
A6J74_RS19195	COG2151	metal-sulfur cluster biosynthetic enzyme
A6J74_RS19200	COG0840	transmembrane signaling receptor activity
A6J74_RS19205	COG0840	transmembrane signaling receptor activity
A6J74_RS19215	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A6J74_RS19225	COG5002	protein histidine kinase activity
A6J74_RS19230	COG0745	RESPONSE REGULATOR receiver
A6J74_RS19235	COG1376	ErfK ybiS ycfS ynhG family protein
A6J74_RS19245	COG0586	Pfam SNARE associated Golgi protein
A6J74_RS19285	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A6J74_RS19310	COG0531	amino acid
A6J74_RS19315	COG2814	Major facilitator Superfamily
A6J74_RS19330	COG0840	transmembrane signaling receptor activity
A6J74_RS19335	COG0011	TIGRFAM Protein of
A6J74_RS19345	COG0506	proline dehydrogenase activity
A6J74_RS19350	COG1686	Belongs to the peptidase S11 family
A6J74_RS19365	COG1250	3-hydroxyacyl-CoA dehydrogenase
A6J74_RS19365	COG1024	Enoyl-CoA hydratase
A6J74_RS19370	COG0183	Belongs to the thiolase family
A6J74_RS19375	COG1960	acyl-CoA dehydrogenase activity
A6J74_RS19380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A6J74_RS19400	COG0039	L-malate dehydrogenase activity
A6J74_RS19420	COG1393	Belongs to the ArsC family
A6J74_RS19430	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
A6J74_RS19435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A6J74_RS19450	COG2011	ABC-type metal ion transport system permease component
A6J74_RS19455	COG1464	Belongs to the NlpA lipoprotein family
A6J74_RS19460	COG1464	Belongs to the NlpA lipoprotein family
A6J74_RS19465	COG0396	ATPase activity
A6J74_RS19470	COG0719	Fe-S assembly protein
A6J74_RS19475	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A6J74_RS19480	COG0822	iron-sulfur transferase activity
A6J74_RS19485	COG0719	Fe-S assembly protein
A6J74_RS19495	COG0737	Belongs to the 5'-nucleotidase family
A6J74_RS19500	COG3377	Domain of unknown function (DUF1805)
A6J74_RS19510	COG0739	heme binding
A6J74_RS19535	COG4377	Putative membrane peptidase family (DUF2324)
A6J74_RS19540	COG0789	Transcriptional regulator
A6J74_RS19550	COG4470	Protein conserved in bacteria
A6J74_RS19575	COG1494	fructose-1,6-bisphosphatase
A6J74_RS19580	COG2445	Protein of unknown function DUF86
A6J74_RS19590	COG0647	UMP catabolic process
A6J74_RS19600	COG2249	NAD(P)H dehydrogenase (quinone) activity
A6J74_RS19625	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
A6J74_RS19630	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A6J74_RS19645	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
A6J74_RS19650	COG4837	Protein of unknown function (DUF1462)
A6J74_RS19685	COG2824	Alkylphosphonate utilization operon protein PhnA
A6J74_RS19690	COG0390	transport system, permease component
A6J74_RS19695	COG2274	protein secretion by the type I secretion system
A6J74_RS19705	COG1252	NADH dehydrogenase
A6J74_RS19720	COG0316	Belongs to the HesB IscA family
A6J74_RS19745	COG1683	Conserved Protein
A6J74_RS19765	COG3708	Transcriptional regulator
A6J74_RS19775	COG1252	NADH dehydrogenase
A6J74_RS19790	COG3584	3D domain protein
A6J74_RS19805	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A6J74_RS19810	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A6J74_RS19815	COG1268	BioY protein
A6J74_RS19825	COG2050	protein possibly involved in aromatic compounds catabolism
A6J74_RS19850	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A6J74_RS19855	COG5018	Exonuclease
A6J74_RS19870	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
A6J74_RS19880	COG2267	carboxylic ester hydrolase activity
A6J74_RS19885	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A6J74_RS19890	COG1522	sequence-specific DNA binding
A6J74_RS19895	COG0436	Aminotransferase
A6J74_RS19900	COG1098	S1 RNA binding domain
A6J74_RS19905	COG2155	Conserved Protein
A6J74_RS19925	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A6J74_RS19930	COG1285	pathogenesis
A6J74_RS19970	COG0544	peptidyl-prolyl cis-trans isomerase activity
A6J74_RS20105	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
A6J74_RS20110	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
A6J74_RS20120	COG0058	SHG alpha-glucan phosphorylase activity
A6J74_RS20145	COG1278	Cold shock
A6J74_RS20150	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A6J74_RS20155	COG1575	Belongs to the MenA family. Type 1 subfamily
A6J74_RS20160	COG1169	isochorismate synthase
A6J74_RS20170	COG0596	Alpha beta hydrolase
A6J74_RS20175	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
A6J74_RS20185	COG4948	Mandelate Racemase Muconate Lactonizing
A6J74_RS20190	COG0745	RESPONSE REGULATOR receiver
A6J74_RS20210	COG3964	amidohydrolase
A6J74_RS20230	COG2188	Transcriptional regulator
A6J74_RS20245	COG0577	efflux transmembrane transporter activity
A6J74_RS20250	COG1136	(ABC) transporter
A6J74_RS20255	COG0577	efflux transmembrane transporter activity
A6J74_RS20260	COG0577	efflux transmembrane transporter activity
A6J74_RS20265	COG2205	protein histidine kinase activity
A6J74_RS20270	COG0745	RESPONSE REGULATOR receiver
A6J74_RS20275	COG1595	DNA-templated transcription, initiation
A6J74_RS20290	COG0640	Transcriptional regulator
A6J74_RS20295	COG5658	integral membrane protein
A6J74_RS20300	COG1131	(ABC) transporter
A6J74_RS20310	COG3708	Transcriptional regulator
A6J74_RS20310	COG2207	Transcriptional regulator
A6J74_RS20315	COG1136	(ABC) transporter
A6J74_RS20320	COG0577	efflux transmembrane transporter activity
A6J74_RS20325	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
A6J74_RS20330	COG0586	Pfam SNARE associated Golgi protein
A6J74_RS20345	COG1136	(ABC) transporter
A6J74_RS20350	COG0577	efflux transmembrane transporter activity
A6J74_RS20375	COG1597	lipid kinase activity
A6J74_RS20380	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
A6J74_RS20405	COG0745	RESPONSE REGULATOR receiver
A6J74_RS20410	COG5002	protein histidine kinase activity
A6J74_RS20440	COG1842	Phage shock protein A
A6J74_RS20465	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A6J74_RS20480	COG1294	oxidase, subunit
A6J74_RS20485	COG1271	oxidase subunit
A6J74_RS20490	COG0288	reversible hydration of carbon dioxide
A6J74_RS20500	COG1854	S-ribosylhomocysteine lyase activity
A6J74_RS20530	COG0494	nUDIX hydrolase
A6J74_RS20555	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A6J74_RS20560	COG1116	anion transmembrane transporter activity
A6J74_RS20565	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A6J74_RS20580	COG1368	sulfuric ester hydrolase activity
A6J74_RS20585	COG2267	carboxylic ester hydrolase activity
A6J74_RS20595	COG3852	Histidine kinase
A6J74_RS20600	COG3852	Histidine kinase
A6J74_RS20670	COG0438	transferase activity, transferring glycosyl groups
A6J74_RS20675	COG0671	phosphoesterase, PA-phosphatase related
A6J74_RS20680	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
A6J74_RS20685	COG2267	carboxylic ester hydrolase activity
A6J74_RS20705	COG1794	racemase activity, acting on amino acids and derivatives
A6J74_RS20710	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
A6J74_RS20715	COG1242	4 iron, 4 sulfur cluster binding
A6J74_RS20735	COG1136	(ABC) transporter
A6J74_RS20750	COG0582	viral genome integration into host DNA
A6J74_RS20755	COG0490	domain, Protein
A6J74_RS20760	COG0475	glutathione-regulated potassium exporter activity
A6J74_RS20765	COG2814	Major facilitator Superfamily
A6J74_RS20810	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
A6J74_RS20820	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A6J74_RS20840	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A6J74_RS20845	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A6J74_RS20855	COG0303	'Molybdopterin
A6J74_RS20860	COG1763	Mo-molybdopterin cofactor biosynthetic process
A6J74_RS20865	COG0314	molybdopterin synthase activity
A6J74_RS20890	COG1329	Transcriptional regulator
A6J74_RS20915	COG3832	glyoxalase III activity
A6J74_RS20925	COG2814	Major facilitator Superfamily
A6J74_RS20930	COG2081	HI0933 family
A6J74_RS20935	COG2244	polysaccharide biosynthetic process
A6J74_RS20940	COG1187	pseudouridine synthase activity
A6J74_RS20945	COG1349	DNA-binding transcription factor activity
A6J74_RS20950	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A6J74_RS20965	COG1523	belongs to the glycosyl hydrolase 13 family
A6J74_RS20970	COG0510	thiamine kinase activity
A6J74_RS20985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A6J74_RS20995	COG1363	Peptidase, m42
A6J74_RS21000	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
A6J74_RS21005	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A6J74_RS21010	COG4848	Belongs to the UPF0354 family
A6J74_RS21015	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A6J74_RS21025	COG1388	LysM domain
A6J74_RS21025	COG0860	N-Acetylmuramoyl-L-alanine amidase
A6J74_RS21030	COG1674	ftsk spoiiie
A6J74_RS21045	COG0789	Transcriptional regulator
A6J74_RS21050	COG0697	spore germination
A6J74_RS21075	COG2309	aminopeptidase activity
A6J74_RS21085	COG3118	belongs to the thioredoxin family
A6J74_RS21090	COG4851	CamS sex pheromone cAM373 precursor
A6J74_RS21105	COG1609	Transcriptional regulator
A6J74_RS21135	COG0666	response to abiotic stimulus
A6J74_RS21140	COG5002	protein histidine kinase activity
A6J74_RS21145	COG0745	RESPONSE REGULATOR receiver
A6J74_RS21160	COG0123	including yeast histone deacetylase and acetoin utilization protein
A6J74_RS21165	COG0517	IMP dehydrogenase activity
A6J74_RS21170	COG0454	-acetyltransferase
A6J74_RS21175	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A6J74_RS21180	COG0110	maltose O-acetyltransferase activity
A6J74_RS21190	COG1595	DNA-templated transcription, initiation
A6J74_RS21230	COG0626	cystathionine gamma-synthase activity
A6J74_RS21235	COG1956	GAF domain-containing protein
A6J74_RS21240	COG1309	transcriptional regulator
A6J74_RS21245	COG0697	spore germination
A6J74_RS21250	COG0583	DNA-binding transcription factor activity
A6J74_RS21255	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
A6J74_RS21260	COG1104	cysteine desulfurase activity
A6J74_RS21275	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A6J74_RS21285	COG1574	metal-dependent hydrolase with the TIM-barrel fold
A6J74_RS21300	COG3874	Sporulation protein YtfJ
A6J74_RS21305	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
A6J74_RS21310	COG0827	DNA restriction-modification system
A6J74_RS21335	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A6J74_RS21375	COG0346	lactoylglutathione lyase activity
A6J74_RS21380	COG0589	response to stress
A6J74_RS21385	COG1028	Short-chain dehydrogenase reductase Sdr
A6J74_RS21400	COG0662	Cupin 2, conserved barrel domain protein
A6J74_RS21435	COG0006	proline dipeptidase activity
A6J74_RS21450	COG4109	DRTGG domain
A6J74_RS21465	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
A6J74_RS21480	COG0587	DNA-directed DNA polymerase activity
A6J74_RS21485	COG0281	malic enzyme
A6J74_RS21490	COG1725	Transcriptional regulator
A6J74_RS21515	COG3030	protein affecting phage T7 exclusion by the F plasmid
A6J74_RS21520	COG0628	permease
A6J74_RS21535	COG0372	Belongs to the citrate synthase family
A6J74_RS21540	COG0538	isocitrate dehydrogenase activity
A6J74_RS21565	COG0745	RESPONSE REGULATOR receiver
A6J74_RS21570	COG5002	protein histidine kinase activity
A6J74_RS21575	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A6J74_RS21575	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A6J74_RS21585	COG1971	Probably functions as a manganese efflux pump
A6J74_RS21590	COG0237	dephospho-CoA kinase activity
A6J74_RS21595	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A6J74_RS21605	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
A6J74_RS21620	COG3611	Membrane attachment protein
A6J74_RS21625	COG1484	DNA-dependent DNA replication
A6J74_RS21635	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A6J74_RS21660	COG1363	Peptidase, m42
A6J74_RS21665	COG1309	transcriptional regulator
A6J74_RS21670	COG1566	PFAM secretion protein HlyD family protein
A6J74_RS21675	COG2814	Major facilitator Superfamily
A6J74_RS21700	COG1418	mRNA catabolic process
A6J74_RS21710	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A6J74_RS21740	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
A6J74_RS21745	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
A6J74_RS21750	COG1286	toxin biosynthetic process
A6J74_RS21755	COG1796	DNA polymerase
A6J74_RS21755	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A6J74_RS21770	COG1187	pseudouridine synthase activity
A6J74_RS21775	COG1114	Component of the transport system for branched-chain amino acids
A6J74_RS21780	COG5386	Cell surface protein
A6J74_RS21790	COG5386	Cell surface protein
A6J74_RS21805	COG1120	ATPase activity
A6J74_RS21810	COG4509	Sortase family
A6J74_RS21820	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
A6J74_RS21825	COG4895	conserved protein (DUF2196)
A6J74_RS21835	COG0745	RESPONSE REGULATOR receiver
A6J74_RS21840	COG2205	protein histidine kinase activity
A6J74_RS21845	COG1131	(ABC) transporter
A6J74_RS21875	COG2318	DinB family
A6J74_RS21905	COG0318	PFAM AMP-dependent synthetase and ligase
A6J74_RS21910	COG1309	transcriptional regulator
A6J74_RS21915	COG1024	Enoyl-CoA hydratase
A6J74_RS21920	COG2086	electron transfer activity
A6J74_RS21925	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
A6J74_RS21930	COG3118	belongs to the thioredoxin family
A6J74_RS21935	COG0322	excinuclease ABC activity
A6J74_RS21940	COG1719	4-vinyl reductase, 4VR
A6J74_RS21945	COG2009	succinate dehydrogenase
A6J74_RS21950	COG1053	succinate dehydrogenase
A6J74_RS21955	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A6J74_RS21960	COG0824	Thioesterase
A6J74_RS21965	COG1876	peptidase activity
A6J74_RS21970	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
A6J74_RS21975	COG1360	Flagellar Motor Protein
A6J74_RS21980	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
A6J74_RS21985	COG4152	abc transporter atp-binding protein
A6J74_RS21990	COG1668	transmembrane transport
A6J74_RS21995	COG1959	2 iron, 2 sulfur cluster binding
A6J74_RS22005	COG0697	spore germination
A6J74_RS22010	COG1396	sequence-specific DNA binding
A6J74_RS22015	COG1983	PspC domain protein
A6J74_RS22020	COG0402	S-adenosylhomocysteine deaminase activity
A6J74_RS22025	COG2233	PERMEase
A6J74_RS22030	COG2197	response regulator
A6J74_RS22045	COG5401	PFAM Sporulation and spore germination
A6J74_RS22060	COG0622	Phosphoesterase
A6J74_RS22110	COG1067	ATP-dependent peptidase activity
A6J74_RS22110	COG0470	DNA polymerase III
A6J74_RS22125	COG1764	response to oxidative stress
A6J74_RS22130	COG1846	Transcriptional regulator
A6J74_RS22140	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A6J74_RS22150	COG1587	Uroporphyrinogen-III synthase
A6J74_RS22155	COG0113	porphobilinogen synthase activity
A6J74_RS22165	COG1388	LysM domain
A6J74_RS22180	COG0285	dihydrofolate synthase activity
A6J74_RS22205	COG1077	Cell shape determining protein MreB Mrl
A6J74_RS22225	COG2894	cell division
A6J74_RS22230	COG0739	heme binding
A6J74_RS22235	COG1994	Peptidase M50
A6J74_RS22240	COG1530	ribonuclease E activity
A6J74_RS22250	COG2868	ribosomal protein
A6J74_RS22260	COG3290	protein histidine kinase activity
A6J74_RS22270	COG0745	RESPONSE REGULATOR receiver
A6J74_RS22275	COG5002	protein histidine kinase activity
A6J74_RS22280	COG1136	(ABC) transporter
A6J74_RS22285	COG0577	efflux transmembrane transporter activity
A6J74_RS22290	COG0577	efflux transmembrane transporter activity
A6J74_RS22295	COG0077	Prephenate dehydratase
A6J74_RS22300	COG2258	MOSC domain
A6J74_RS22305	COG1827	regulation of RNA biosynthetic process
A6J74_RS22310	COG1104	cysteine desulfurase activity
A6J74_RS22315	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
A6J74_RS22320	COG0157	Belongs to the NadC ModD family
A6J74_RS22350	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
A6J74_RS22355	COG0632	four-way junction helicase activity
A6J74_RS22360	COG2255	four-way junction helicase activity
A6J74_RS22375	COG0343	queuine tRNA-ribosyltransferase activity
A6J74_RS22380	COG1862	Preprotein translocase
A6J74_RS22390	COG2323	membrane
A6J74_RS22395	COG2244	polysaccharide biosynthetic process
A6J74_RS22405	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A6J74_RS22405	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A6J74_RS22410	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A6J74_RS22415	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A6J74_RS22415	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
A6J74_RS22425	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A6J74_RS22460	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
A6J74_RS22480	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A6J74_RS22485	COG1959	2 iron, 2 sulfur cluster binding
A6J74_RS22490	COG1104	cysteine desulfurase activity
A6J74_RS22505	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A6J74_RS22525	COG0628	permease
A6J74_RS22540	COG4472	Bacterial protein of unknown function (DUF965)
A6J74_RS22555	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A6J74_RS22560	COG4122	O-methyltransferase activity
A6J74_RS22565	COG0826	peptidase U32
A6J74_RS22570	COG0826	peptidase U32
A6J74_RS22585	COG0768	penicillin binding
A6J74_RS22610	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A6J74_RS22615	COG0626	cystathionine gamma-synthase activity
A6J74_RS22620	COG1012	belongs to the aldehyde dehydrogenase family
A6J74_RS22620	COG1454	alcohol dehydrogenase
A6J74_RS22635	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
A6J74_RS22675	COG2259	Doxx family
A6J74_RS22680	COG2514	catechol 2,3-dioxygenase activity
A6J74_RS22690	COG3186	Phenylalanine-4-hydroxylase
A6J74_RS22700	COG1404	Belongs to the peptidase S8 family
A6J74_RS22735	COG2267	carboxylic ester hydrolase activity
A6J74_RS22745	COG1785	Belongs to the alkaline phosphatase family
A6J74_RS22755	COG2357	RelA SpoT domain protein
A6J74_RS22760	COG0778	Nitroreductase
A6J74_RS22795	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
A6J74_RS22800	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
A6J74_RS22810	COG1534	Rna-binding protein
A6J74_RS22815	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
A6J74_RS22820	COG1713	HD superfamily hydrolase involved in NAD metabolism
A6J74_RS22825	COG0799	negative regulation of ribosome biogenesis
A6J74_RS22830	COG2226	methyltransferase
A6J74_RS22835	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A6J74_RS22840	COG1596	polysaccharide export
A6J74_RS22840	COG1555	photosystem II stabilization
A6J74_RS22845	COG2131	deaminase
A6J74_RS22850	COG0658	competence protein
A6J74_RS22850	COG2333	competence protein COMEC
A6J74_RS22860	COG1466	dna polymerase III delta subunit
A6J74_RS22885	COG1733	regulation of RNA biosynthetic process
A6J74_RS22890	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A6J74_RS22895	COG1420	regulation of RNA biosynthetic process
A6J74_RS22910	COG0484	heat shock protein binding
A6J74_RS22920	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A6J74_RS22925	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A6J74_RS22930	COG0828	Belongs to the bacterial ribosomal protein bS21 family
A6J74_RS22935	COG1610	YqeY-like protein
A6J74_RS22955	COG1702	phosphate starvation-inducible protein PhoH
A6J74_RS22960	COG1480	7TM receptor with intracellular HD hydrolase
A6J74_RS22965	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
A6J74_RS22970	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
A6J74_RS22975	COG0295	cytidine deaminase activity
A6J74_RS22980	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
A6J74_RS22995	COG0517	IMP dehydrogenase activity
A6J74_RS23005	COG1671	Belongs to the UPF0178 family
A6J74_RS23010	COG0358	DNA primase activity
A6J74_RS23015	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A6J74_RS23020	COG2010	Cytochrome c
A6J74_RS23025	COG2384	SAM-dependent methyltransferase
A6J74_RS23030	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A6J74_RS23060	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A6J74_RS23065	COG1121	(ABC) transporter
A6J74_RS23070	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A6J74_RS23075	COG0735	belongs to the Fur family
A6J74_RS23100	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A6J74_RS23105	COG0477	Major facilitator Superfamily
A6J74_RS23110	COG0768	penicillin binding
A6J74_RS23115	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A6J74_RS23120	COG0573	inorganic phosphate transmembrane transporter activity
A6J74_RS23125	COG0581	inorganic phosphate transmembrane transporter activity
A6J74_RS23135	COG0704	Plays a role in the regulation of phosphate uptake
A6J74_RS23140	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A6J74_RS23145	COG0267	Belongs to the bacterial ribosomal protein bL33 family
A6J74_RS23150	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A6J74_RS23155	COG4483	Protein conserved in bacteria
A6J74_RS23160	COG1940	carbohydrate kinase activity
A6J74_RS23170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A6J74_RS23195	COG0626	cystathionine gamma-synthase activity
A6J74_RS23200	COG0626	cystathionine gamma-synthase activity
A6J74_RS23205	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
A6J74_RS23205	COG0646	methionine synthase
A6J74_RS23210	COG1410	methionine synthase
A6J74_RS23210	COG0646	methionine synthase
A6J74_RS23265	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A6J74_RS23270	COG1459	type II secretion system
A6J74_RS23280	COG4970	Tfp pilus assembly protein FimT
A6J74_RS23340	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A6J74_RS23345	COG0404	The glycine cleavage system catalyzes the degradation of glycine
A6J74_RS23355	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A6J74_RS23370	COG1725	Transcriptional regulator
A6J74_RS23375	COG1131	(ABC) transporter
A6J74_RS23410	COG2076	Multidrug Resistance protein
A6J74_RS23415	COG2076	Multidrug Resistance protein
A6J74_RS23425	COG1609	Transcriptional regulator
A6J74_RS23435	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A6J74_RS23440	COG0095	Lipoate-protein ligase
A6J74_RS23470	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A6J74_RS23480	COG3872	metal-dependent enzyme
A6J74_RS23495	COG0006	proline dipeptidase activity
A6J74_RS23520	COG3854	ATPases associated with a variety of cellular activities
A6J74_RS23565	COG0511	ligase activity, forming carbon-carbon bonds
A6J74_RS23570	COG0439	Biotin carboxylase
A6J74_RS23575	COG1302	Protein conserved in bacteria
A6J74_RS23580	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A6J74_RS23600	COG0142	geranyltranstransferase activity
A6J74_RS23610	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
A6J74_RS23620	COG0497	DNA recombination
A6J74_RS23625	COG0750	zinc metalloprotease
A6J74_RS23635	COG0745	RESPONSE REGULATOR receiver
A6J74_RS23645	COG1215	transferase activity, transferring glycosyl groups
A6J74_RS23650	COG3093	addiction module antidote protein HigA
A6J74_RS23655	COG0584	glycerophosphoryl diester phosphodiesterase
A6J74_RS23665	COG3829	transcription factor binding
A6J74_RS23665	COG3290	protein histidine kinase activity
A6J74_RS23675	COG0280	phosphate acetyltransferase
A6J74_RS23690	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A6J74_RS23695	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A6J74_RS23700	COG0022	dehydrogenase e1 component
A6J74_RS23705	COG0508	dehydrogenase complex catalyzes the overall conversion of
A6J74_RS23715	COG0772	Belongs to the SEDS family
A6J74_RS23720	COG2323	membrane
A6J74_RS23725	COG2816	NAD+ diphosphatase activity
A6J74_RS23745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6J74_RS23750	COG0765	amino acid transport
A6J74_RS23755	COG1126	abc transporter atp-binding protein
A6J74_RS23760	COG4129	membrane
A6J74_RS23765	COG1376	ErfK ybiS ycfS ynhG family protein
A6J74_RS23780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A6J74_RS23785	COG2195	Cleaves the N-terminal amino acid of tripeptides
A6J74_RS23800	COG1285	pathogenesis
A6J74_RS23825	COG1760	l-serine dehydratase
A6J74_RS23830	COG1760	l-serine dehydratase
A6J74_RS23835	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A6J74_RS23840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A6J74_RS23845	COG0300	oxidoreductase activity
A6J74_RS23855	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
A6J74_RS23890	COG1522	sequence-specific DNA binding
A6J74_RS23900	COG0737	Belongs to the 5'-nucleotidase family
A6J74_RS23905	COG1757	Na H antiporter
A6J74_RS23920	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A6J74_RS23935	COG1073	alpha beta
A6J74_RS23935	COG2226	methyltransferase
A6J74_RS23940	COG4106	trans-aconitate 2-methyltransferase activity
A6J74_RS23965	COG0307	riboflavin synthase, alpha
A6J74_RS23970	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A6J74_RS23970	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A6J74_RS23990	COG1073	alpha beta
A6J74_RS23995	COG0454	-acetyltransferase
A6J74_RS24000	COG1609	Transcriptional regulator
A6J74_RS24005	COG2056	Na+-H+ antiporter family
A6J74_RS24010	COG0596	Alpha beta hydrolase
A6J74_RS24020	COG1525	nuclease
A6J74_RS24020	COG4085	toxin activity
A6J74_RS24020	COG0737	Belongs to the 5'-nucleotidase family
A6J74_RS24030	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
A6J74_RS24030	COG0456	acetyltransferase
A6J74_RS24035	COG0656	L-ascorbic acid biosynthetic process
A6J74_RS24040	COG0667	Aldo Keto reductase
A6J74_RS24060	COG1300	Membrane
A6J74_RS24065	COG0735	belongs to the Fur family
A6J74_RS24075	COG4974	Belongs to the 'phage' integrase family
A6J74_RS24100	COG0598	Magnesium transport protein CorA
A6J74_RS24115	COG1846	Transcriptional regulator
A6J74_RS24140	COG1131	(ABC) transporter
A6J74_RS24145	COG1725	Transcriptional regulator
A6J74_RS24155	COG1686	Belongs to the peptidase S11 family
A6J74_RS24175	COG0733	neurotransmitter:sodium symporter activity
A6J74_RS24200	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A6J74_RS24215	COG0697	spore germination
A6J74_RS24220	COG0561	phosphatase activity
A6J74_RS24225	COG4086	secreted protein
A6J74_RS24230	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A6J74_RS24235	COG0456	acetyltransferase
A6J74_RS24240	COG1547	Domain of unknown function (DUF309)
A6J74_RS24270	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A6J74_RS24280	COG2188	Transcriptional regulator
A6J74_RS24290	COG3711	transcriptional antiterminator
A6J74_RS24295	COG1263	PTS System
A6J74_RS24295	COG2190	(PTS) system
A6J74_RS24295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A6J74_RS24320	COG0778	Nitroreductase
A6J74_RS24325	COG2199	diguanylate cyclase activity
A6J74_RS24335	COG2084	Dehydrogenase
A6J74_RS24370	COG0436	Aminotransferase
A6J74_RS24375	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A6J74_RS24380	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
A6J74_RS24395	COG1028	Short-chain dehydrogenase reductase Sdr
A6J74_RS24400	COG1695	Transcriptional regulator
A6J74_RS24435	COG0183	Belongs to the thiolase family
A6J74_RS24480	COG3842	ATPase activity
A6J74_RS24485	COG0366	Alpha amylase catalytic
A6J74_RS24495	COG2182	Extracellular solute-binding protein
A6J74_RS24500	COG1175	transmembrane transport
A6J74_RS24505	COG3833	ABC-type maltose transport systems, permease component
A6J74_RS24510	COG1609	Transcriptional regulator
A6J74_RS24515	COG0436	Aminotransferase
A6J74_RS24525	COG2205	protein histidine kinase activity
A6J74_RS24540	COG3209	COG3209 Rhs family protein
A6J74_RS24560	COG2814	Major facilitator Superfamily
A6J74_RS24595	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
A6J74_RS24605	COG1408	metallophosphoesterase
A6J74_RS24610	COG1028	Short-chain dehydrogenase reductase Sdr
A6J74_RS24615	COG2200	EAL domain
A6J74_RS24630	COG4703	Protein of unknown function (DUF1797)
A6J74_RS24640	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
A6J74_RS24650	COG0517	IMP dehydrogenase activity
A6J74_RS24655	COG0583	DNA-binding transcription factor activity
A6J74_RS24660	COG2171	N-acyltransferase activity
A6J74_RS24675	COG0569	domain protein
A6J74_RS24680	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A6J74_RS24685	COG5503	Protein of unknown function (DUF1447)
A6J74_RS24695	COG0561	phosphatase activity
A6J74_RS24710	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A6J74_RS24715	COG0022	dehydrogenase e1 component
A6J74_RS24775	COG1982	Orn Lys Arg decarboxylase major
A6J74_RS24795	COG0483	inositol monophosphate 1-phosphatase activity
A6J74_RS24805	COG1217	gtp-binding protein TYPA
A6J74_RS24820	COG4896	Protein conserved in bacteria
A6J74_RS24830	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
A6J74_RS24835	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
A6J74_RS24845	COG0772	Belongs to the SEDS family
A6J74_RS24855	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
A6J74_RS24890	COG3336	cytochrome c oxidase
A6J74_RS24905	COG2340	Cysteine-rich secretory protein family
A6J74_RS24920	COG0406	alpha-ribazole phosphatase activity
A6J74_RS24925	COG3679	Belongs to the UPF0342 family
A6J74_RS24940	COG0742	ribosomal rna small subunit methyltransferase
A6J74_RS24950	COG3314	Sporulation integral membrane protein YlbJ
A6J74_RS24955	COG1752	Esterase of the alpha-beta hydrolase superfamily
A6J74_RS24960	COG3480	Lon protease (S16) C-terminal proteolytic domain
A6J74_RS24970	COG1399	metal-binding, possibly nucleic acid-binding protein
A6J74_RS24975	COG0333	Belongs to the bacterial ribosomal protein bL32 family
A6J74_RS24990	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A6J74_RS25010	COG0768	penicillin binding
A6J74_RS25015	COG0768	penicillin binding
A6J74_RS25035	COG0772	Belongs to the SEDS family
A6J74_RS25050	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
A6J74_RS25055	COG0849	cell division
A6J74_RS25060	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A6J74_RS25070	COG1191	sigma factor activity
A6J74_RS25075	COG1191	sigma factor activity
A6J74_RS25080	COG1873	PFAM PRC-barrel domain
A6J74_RS25090	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
A6J74_RS25095	COG1799	cell septum assembly
A6J74_RS25100	COG0762	integral membrane protein
A6J74_RS25105	COG2302	S4 RNA-binding domain
A6J74_RS25110	COG3599	regulation of cell shape
A6J74_RS25130	COG0564	pseudouridine synthase activity
A6J74_RS25190	COG3069	C4-dicarboxylate transmembrane transporter activity
A6J74_RS25210	COG0006	proline dipeptidase activity
A6J74_RS25220	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A6J74_RS25225	COG1561	YicC-like family, N-terminal region
A6J74_RS25245	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A6J74_RS25250	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A6J74_RS25260	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
A6J74_RS25265	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A6J74_RS25265	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A6J74_RS25275	COG0631	protein serine/threonine phosphatase activity
A6J74_RS25280	COG0515	serine threonine protein kinase
A6J74_RS25280	COG2815	serine threonine protein kinase
A6J74_RS25285	COG1162	GTPase activity
A6J74_RS25290	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A6J74_RS25295	COG1564	THIamine pyrophosphokinase
A6J74_RS25310	COG1302	Protein conserved in bacteria
A6J74_RS25315	COG1461	Dihydroxyacetone kinase
A6J74_RS25320	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A6J74_RS25335	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A6J74_RS25340	COG1028	Short-chain dehydrogenase reductase Sdr
A6J74_RS25345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A6J74_RS25355	COG1196	nuclear chromosome segregation
A6J74_RS25360	COG0552	protein localization to endoplasmic reticulum
A6J74_RS25370	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A6J74_RS25380	COG1837	Belongs to the UPF0109 family
A6J74_RS25395	COG0335	large ribosomal subunit rRNA binding
A6J74_RS25420	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
A6J74_RS25425	COG0758	DNA mediated transformation
A6J74_RS25430	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A6J74_RS25440	COG4974	Belongs to the 'phage' integrase family
A6J74_RS25465	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
A6J74_RS25470	COG0528	UMP kinase activity
A6J74_RS25485	COG4589	Belongs to the CDS family
A6J74_RS25495	COG0750	zinc metalloprotease
A6J74_RS25520	COG0195	Participates in both transcription termination and antitermination
A6J74_RS25525	COG2740	Nucleic-acid-binding protein implicated in transcription termination
A6J74_RS25530	COG1358	cellular component organization or biogenesis
A6J74_RS25540	COG1550	Protein conserved in bacteria
A6J74_RS25545	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
A6J74_RS25555	COG0196	riboflavin kinase activity
A6J74_RS25570	COG0726	polysaccharide deacetylase
A6J74_RS25575	COG0612	Peptidase, M16
A6J74_RS25580	COG1873	PFAM PRC-barrel domain
A6J74_RS25585	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A6J74_RS25590	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A6J74_RS25595	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A6J74_RS25600	COG0527	aspartate kinase activity
A6J74_RS25610	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A6J74_RS25615	COG0740	serine-type endopeptidase activity
A6J74_RS25625	COG1674	ftsk spoiiie
A6J74_RS25635	COG2188	Transcriptional regulator
A6J74_RS25640	COG1744	ABC transporter substrate-binding protein PnrA-like
A6J74_RS25645	COG3845	ABC transporter
A6J74_RS25650	COG4603	Belongs to the binding-protein-dependent transport system permease family
A6J74_RS25655	COG1079	Belongs to the binding-protein-dependent transport system permease family
A6J74_RS25660	COG0612	Peptidase, M16
A6J74_RS25665	COG0612	Peptidase, M16
A6J74_RS25670	COG0300	oxidoreductase activity
A6J74_RS25685	COG1426	Protein conserved in bacteria
A6J74_RS25690	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A6J74_RS25725	COG1692	metallophosphoesterase
A6J74_RS25730	COG2359	stage V sporulation protein S
A6J74_RS25740	COG0674	pyruvate-flavodoxin oxidoreductase activity
A6J74_RS25740	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A6J74_RS25745	COG1013	pyruvate-flavodoxin oxidoreductase activity
A6J74_RS25755	COG4550	Control of competence regulator ComK, YlbF/YmcA
A6J74_RS25770	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
A6J74_RS25785	COG1368	sulfuric ester hydrolase activity
A6J74_RS25800	COG3773	Cell wall hydrolase
A6J74_RS25805	COG1404	Belongs to the peptidase S8 family
A6J74_RS25825	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A6J74_RS25830	COG0508	dehydrogenase complex catalyzes the overall conversion of
A6J74_RS25830	COG0596	Alpha beta hydrolase
A6J74_RS25835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A6J74_RS25845	COG1346	cytolysis
A6J74_RS25885	COG3300	MHYT domain
A6J74_RS25885	COG5001	Diguanylate cyclase
A6J74_RS25890	COG2267	carboxylic ester hydrolase activity
A6J74_RS25905	COG2364	Membrane
A6J74_RS25915	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
A6J74_RS25920	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A6J74_RS25925	COG2169	Transcriptional regulator
A6J74_RS25930	COG0708	Exodeoxyribonuclease III
A6J74_RS25935	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A6J74_RS25940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A6J74_RS25945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A6J74_RS25950	COG1120	ATPase activity
A6J74_RS25955	COG2819	hydrolase of the alpha beta superfamily
A6J74_RS25975	COG1937	Protein conserved in bacteria
A6J74_RS25980	COG2608	mercury ion transmembrane transporter activity
A6J74_RS25985	COG2217	Heavy metal translocating P-type atpase
A6J74_RS26005	COG1408	metallophosphoesterase
A6J74_RS26010	COG1473	amidohydrolase
A6J74_RS26025	COG1113	amino acid transport
A6J74_RS26040	COG2322	membrane
A6J74_RS26045	COG1979	alcohol dehydrogenase
A6J74_RS26050	COG1349	DNA-binding transcription factor activity
A6J74_RS26055	COG1105	Belongs to the carbohydrate kinase PfkB family
A6J74_RS26060	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A6J74_RS26060	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A6J74_RS26060	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A6J74_RS26070	COG1388	LysM domain
A6J74_RS26070	COG3584	3D domain protein
A6J74_RS26100	COG0464	growth
A6J74_RS26105	COG2860	membrane
A6J74_RS26110	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A6J74_RS26115	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
A6J74_RS26120	COG0789	Transcriptional regulator
A6J74_RS26125	COG0174	glutamine synthetase
A6J74_RS26145	COG1396	sequence-specific DNA binding
A6J74_RS26245	COG1595	DNA-templated transcription, initiation
A6J74_RS26250	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
A6J74_RS26400	COG5632	N-Acetylmuramoyl-L-alanine amidase
A6J74_RS26435	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
A6J74_RS26470	COG1196	nuclear chromosome segregation
A6J74_RS26470	COG0741	lytic transglycosylase activity
A6J74_RS26470	COG0739	heme binding
A6J74_RS26490	COG0489	protein tyrosine kinase activity
A6J74_RS26495	COG1086	Polysaccharide biosynthesis protein
A6J74_RS26500	COG0438	transferase activity, transferring glycosyl groups
A6J74_RS26505	COG0438	transferase activity, transferring glycosyl groups
A6J74_RS26510	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
A6J74_RS26510	COG0463	Glycosyl transferase, family 2
A6J74_RS26520	COG0438	transferase activity, transferring glycosyl groups
A6J74_RS26545	COG3420	alginic acid biosynthetic process
A6J74_RS26545	COG5434	Belongs to the glycosyl hydrolase 28 family
A6J74_RS26550	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A6J74_RS26555	COG1181	Belongs to the D-alanine--D-alanine ligase family
A6J74_RS26565	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A6J74_RS26570	COG0367	asparagine synthase
A6J74_RS26600	COG1132	(ABC) transporter
A6J74_RS26605	COG1695	Transcriptional regulator
A6J74_RS26625	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
A6J74_RS26635	COG0737	Belongs to the 5'-nucleotidase family
A6J74_RS26650	COG3639	organic phosphonate transmembrane transporter activity
A6J74_RS26670	COG3763	UPF0154 protein
A6J74_RS26675	COG1132	(ABC) transporter
A6J74_RS26680	COG1132	(ABC) transporter
A6J74_RS26710	COG0730	response to heat
A6J74_RS26720	COG1051	belongs to the nudix hydrolase family
A6J74_RS26725	COG1346	cytolysis
A6J74_RS26735	COG0583	DNA-binding transcription factor activity
A6J74_RS26750	COG1131	(ABC) transporter
A6J74_RS26760	COG1473	amidohydrolase
A6J74_RS26775	COG0785	Cytochrome C biogenesis protein
A6J74_RS26780	COG4846	Membrane protein involved in cytochrome C biogenesis
A6J74_RS26810	COG2226	methyltransferase
A6J74_RS26840	COG0010	Belongs to the arginase family
A6J74_RS26845	COG1329	Transcriptional regulator
A6J74_RS26850	COG1902	pentaerythritol trinitrate reductase activity
A6J74_RS26855	COG0069	glutamate synthase activity
A6J74_RS26860	COG0346	lactoylglutathione lyase activity
A6J74_RS26865	COG0400	carboxylic ester hydrolase activity
A6J74_RS26870	COG5002	protein histidine kinase activity
A6J74_RS26880	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A6J74_RS26920	COG1396	sequence-specific DNA binding
A6J74_RS26925	COG0318	PFAM AMP-dependent synthetase and ligase
A6J74_RS26930	COG1268	BioY protein
A6J74_RS26935	COG0318	PFAM AMP-dependent synthetase and ligase
A6J74_RS26940	COG0183	Belongs to the thiolase family
A6J74_RS26955	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A6J74_RS26965	COG2211	Major facilitator Superfamily
A6J74_RS26995	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
A6J74_RS27000	COG1132	(ABC) transporter
A6J74_RS27010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A6J74_RS27035	COG0824	Thioesterase
A6J74_RS27040	COG4841	protein insertion into membrane
A6J74_RS27060	COG0745	RESPONSE REGULATOR receiver
A6J74_RS27065	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A6J74_RS27070	COG1832	CoA-binding protein
A6J74_RS27080	COG0187	DNA topoisomerase II activity
A6J74_RS27085	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A6J74_RS27090	COG0673	inositol 2-dehydrogenase activity
A6J74_RS27100	COG1131	(ABC) transporter
A6J74_RS27110	COG1595	DNA-templated transcription, initiation
A6J74_RS27120	COG1316	TRANSCRIPTIONal
A6J74_RS27125	COG1301	dicarboxylic acid transport
A6J74_RS27130	COG4166	transmembrane transport
A6J74_RS27135	COG4166	transmembrane transport
A6J74_RS27140	COG4166	transmembrane transport
A6J74_RS27145	COG2226	methyltransferase
A6J74_RS27180	COG0531	amino acid
A6J74_RS27200	COG3383	formate dehydrogenase (NAD+) activity
A6J74_RS27205	COG2427	Protein of unknown function (DUF1641)
A6J74_RS27210	COG5609	conserved protein (DUF2294)
A6J74_RS27215	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
A6J74_RS27230	COG2116	formate transmembrane transporter activity
A6J74_RS27235	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A6J74_RS27240	COG0303	'Molybdopterin
A6J74_RS27245	COG0314	molybdopterin synthase activity
A6J74_RS27255	COG0489	protein tyrosine kinase activity
A6J74_RS27270	COG3326	Membrane
A6J74_RS27275	COG2962	Rard protein
A6J74_RS27280	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
A6J74_RS27285	COG1657	PFAM Prenyltransferase squalene oxidase
A6J74_RS27295	COG1028	Short-chain dehydrogenase reductase Sdr
A6J74_RS27300	COG1012	belongs to the aldehyde dehydrogenase family
A6J74_RS27310	COG4145	pantothenate transmembrane transporter activity
A6J74_RS27325	COG0165	Argininosuccinate lyase
A6J74_RS27335	COG1028	Short-chain dehydrogenase reductase Sdr
A6J74_RS27365	COG0716	FMN binding
A6J74_RS27400	COG2720	vancomycin resistance protein
A6J74_RS27405	COG2514	catechol 2,3-dioxygenase activity
A6J74_RS27415	COG1285	pathogenesis
A6J74_RS27425	COG3852	Histidine kinase
A6J74_RS27455	COG1876	peptidase activity
A6J74_RS27470	COG5001	Diguanylate cyclase
A6J74_RS27470	COG3300	MHYT domain
A6J74_RS27480	COG3858	chitin binding
A6J74_RS27495	COG0277	FAD linked oxidase domain protein
A6J74_RS27510	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
A6J74_RS27515	COG2808	Putative FMN-binding domain
A6J74_RS27525	COG0457	Tetratricopeptide repeat
A6J74_RS27535	COG0604	alcohol dehydrogenase
A6J74_RS27540	COG0640	Transcriptional regulator
A6J74_RS27550	COG0584	glycerophosphoryl diester phosphodiesterase
A6J74_RS27560	COG0583	DNA-binding transcription factor activity
A6J74_RS27575	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A6J74_RS27590	COG3781	membrane
A6J74_RS27620	COG1164	Oligoendopeptidase f
A6J74_RS27625	COG2162	N-hydroxyarylamine O-acetyltransferase activity
A6J74_RS27635	COG1193	negative regulation of DNA recombination
A6J74_RS27655	COG0583	DNA-binding transcription factor activity
A6J74_RS27685	COG3739	integral membrane protein
A6J74_RS27690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A6J74_RS27695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A6J74_RS27700	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A6J74_RS27705	COG1247	-acetyltransferase
A6J74_RS27715	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A6J74_RS27720	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A6J74_RS27775	COG2814	Major facilitator Superfamily
A6J74_RS27780	COG0456	acetyltransferase
A6J74_RS27785	COG1113	amino acid transport
A6J74_RS27790	COG0604	alcohol dehydrogenase
A6J74_RS27825	COG2072	flavoprotein involved in K transport
A6J74_RS27860	COG3409	Peptidoglycan-binding domain 1 protein
A6J74_RS27860	COG3757	hydrolase, family 25
A6J74_RS27875	COG1151	hydroxylamine reductase activity
A6J74_RS27935	COG1280	lysine exporter protein (LysE YggA)
A6J74_RS27945	COG1191	sigma factor activity
A6J74_RS27980	COG1733	regulation of RNA biosynthetic process
A6J74_RS27985	COG2249	NAD(P)H dehydrogenase (quinone) activity
A6J74_RS27990	COG0318	PFAM AMP-dependent synthetase and ligase
A6J74_RS28020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A6J74_RS28040	COG0673	inositol 2-dehydrogenase activity
A6J74_RS28045	COG2188	Transcriptional regulator
A6J74_RS28050	COG1733	regulation of RNA biosynthetic process
A6J74_RS28060	COG1393	Belongs to the ArsC family
A6J74_RS28090	COG3655	Transcriptional regulator
A6J74_RS28095	COG0814	amino acid
A6J74_RS28135	COG3321	synthase
A6J74_RS28135	COG0604	alcohol dehydrogenase
A6J74_RS28145	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
A6J74_RS28155	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
A6J74_RS28180	COG2706	6-phosphogluconolactonase activity
A6J74_RS28185	COG3813	Protein conserved in bacteria
A6J74_RS28190	COG1357	PFAM Pentapeptide repeats (8 copies)
A6J74_RS28195	COG0697	spore germination
A6J74_RS28220	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A6J74_RS28230	COG0789	Transcriptional regulator
A6J74_RS28235	COG1253	flavin adenine dinucleotide binding
A6J74_RS28245	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
A6J74_RS28265	COG0477	Major facilitator Superfamily
A6J74_RS28290	COG0628	permease
A6J74_RS28305	COG0110	maltose O-acetyltransferase activity
A6J74_RS28315	COG1940	carbohydrate kinase activity
A6J74_RS28320	COG0346	lactoylglutathione lyase activity
A6J74_RS28345	COG2365	Tyrosine phosphatase family
A6J74_RS28355	COG1011	Hydrolase
A6J74_RS28380	COG1131	(ABC) transporter
A6J74_RS28390	COG1028	Short-chain dehydrogenase reductase Sdr
A6J74_RS28430	COG0778	Nitroreductase
A6J74_RS28435	COG1733	regulation of RNA biosynthetic process
A6J74_RS28455	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A6J74_RS28460	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A6J74_RS28470	COG2356	endonuclease I
A6J74_RS28475	COG1288	antiporter activity
A6J74_RS28530	COG2249	NAD(P)H dehydrogenase (quinone) activity
A6J74_RS28540	COG2031	fatty acid transporter
A6J74_RS28570	COG2814	Major facilitator Superfamily
A6J74_RS28575	COG1846	Transcriptional regulator
A6J74_RS28590	COG0477	Major facilitator Superfamily
A6J74_RS28605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A6J74_RS28610	COG1012	belongs to the aldehyde dehydrogenase family
A6J74_RS28615	COG0534	Mate efflux family protein
A6J74_RS28625	COG1012	belongs to the aldehyde dehydrogenase family
A6J74_RS28630	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A6J74_RS28640	COG2843	Capsule synthesis protein
A6J74_RS28645	COG1876	peptidase activity
A6J74_RS28710	COG2814	Major facilitator Superfamily
A6J74_RS28765	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A6J74_RS28785	COG1619	proteins homologs of microcin C7 resistance protein MccF
A6J74_RS28800	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A6J74_RS28810	COG3850	Histidine kinase
A6J74_RS28810	COG5002	protein histidine kinase activity
A6J74_RS28830	COG0577	efflux transmembrane transporter activity
A6J74_RS28850	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
A6J74_RS28865	COG2515	1-aminocyclopropane-1-carboxylate deaminase
A6J74_RS28870	COG2814	Major facilitator Superfamily
A6J74_RS28875	COG0384	phenazine biosynthesis protein PhzF
A6J74_RS28950	COG0346	lactoylglutathione lyase activity
A6J74_RS28965	COG1522	sequence-specific DNA binding
A6J74_RS28980	COG0697	spore germination
A6J74_RS28985	COG0814	amino acid
A6J74_RS29000	COG2186	Transcriptional regulator
A6J74_RS29010	COG1309	transcriptional regulator
A6J74_RS29025	COG0825	malonyl-CoA metabolic process
A6J74_RS29045	COG0640	Transcriptional regulator
A6J74_RS29050	COG0346	lactoylglutathione lyase activity
A6J74_RS29055	COG0798	PFAM Bile acid sodium symporter
A6J74_RS29085	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
A6J74_RS29090	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A6J74_RS29095	COG1999	signal sequence binding
A6J74_RS29110	COG1121	(ABC) transporter
A6J74_RS29115	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A6J74_RS29120	COG0803	Belongs to the bacterial solute-binding protein 9 family
A6J74_RS29125	COG1575	Belongs to the MenA family. Type 1 subfamily
A6J74_RS29130	COG0456	acetyltransferase
A6J74_RS29140	COG0745	RESPONSE REGULATOR receiver
A6J74_RS29145	COG5002	protein histidine kinase activity
A6J74_RS29175	COG0583	DNA-binding transcription factor activity
A6J74_RS29180	COG2814	Major facilitator Superfamily
A6J74_RS29185	COG5609	conserved protein (DUF2294)
A6J74_RS29190	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A6J74_RS29200	COG0288	reversible hydration of carbon dioxide
A6J74_RS29205	COG0415	Belongs to the DNA photolyase family
A6J74_RS29250	COG1846	Transcriptional regulator
A6J74_RS29255	COG0583	DNA-binding transcription factor activity
A6J74_RS29275	COG1335	isochorismatase
A6J74_RS29280	COG2267	carboxylic ester hydrolase activity
A6J74_RS29290	COG0737	Belongs to the 5'-nucleotidase family
A6J74_RS29295	COG1876	peptidase activity
A6J74_RS29310	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A6J74_RS29325	COG0574	Belongs to the PEP-utilizing enzyme family
A6J74_RS29325	COG3848	Pyruvate phosphate dikinase
A6J74_RS29345	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
A6J74_RS29375	COG3314	Sporulation integral membrane protein YlbJ
A6J74_RS29390	COG1960	acyl-CoA dehydrogenase activity
A6J74_RS29400	COG3142	Participates in the control of copper homeostasis
A6J74_RS29420	COG1414	Transcriptional regulator
A6J74_RS29425	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A6J74_RS29430	COG1984	allophanate hydrolase subunit 2
A6J74_RS29460	COG0768	penicillin binding
A6J74_RS29495	COG4335	DNA alkylation repair
A6J74_RS29505	COG0833	amino acid
A6J74_RS29515	COG0730	response to heat
A6J74_RS29560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A6J74_RS29580	COG0456	acetyltransferase
A6J74_RS29615	COG4884	unkown
A6J74_RS29615	COG3831	ATPase activity
A6J74_RS29640	COG1846	Transcriptional regulator
A6J74_RS29645	COG0778	Nitroreductase