locus-tag class description FHJ82_RS00005 ENOG4105CI4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity) FHJ82_RS00010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) FHJ82_RS00015 ENOG410848D S4 domain protein YaaA FHJ82_RS00020 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) FHJ82_RS00030 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FHJ82_RS00035 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FHJ82_RS00070 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) FHJ82_RS00080 ENOG4105CD9 Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity) FHJ82_RS00085 ENOG4108UHX Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity) FHJ82_RS00090 ENOG4105CGR Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity) FHJ82_RS00095 ENOG4105BZW Glycerate kinase FHJ82_RS00105 ENOG4105ZMH deoxynucleoside kinase FHJ82_RS00115 ENOG4105VRS hydrolase family 18 FHJ82_RS00120 ENOG4105GTG Isochorismatase FHJ82_RS00125 ENOG4108Z6B deaminase FHJ82_RS00135 ENOG4105C6E dna polymerase iii FHJ82_RS00140 ENOG410816I Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity) FHJ82_RS00145 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) FHJ82_RS00155 ENOG41067KS pro-sigma K processing FHJ82_RS00195 ENOG4105CDW Resistance protein FHJ82_RS00200 ENOG4105CXN decarboxylase FHJ82_RS00205 ENOG4108ZMD Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity) FHJ82_RS00210 ENOG4105X0R protein from nitrogen regulatory protein P-II FHJ82_RS00215 ENOG4105XVJ Protein of unknown function (DUF327) FHJ82_RS00220 ENOG4105FA2 dna polymerase iii FHJ82_RS00225 ENOG4105MA4 psp1 domain protein FHJ82_RS00235 ENOG41060K3 Methyltransferase FHJ82_RS00240 ENOG4105VC4 domain protein FHJ82_RS00245 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) FHJ82_RS00250 ENOG4105KRN Transcriptional regulator, abrb family FHJ82_RS00255 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) FHJ82_RS00260 ENOG4105F8V Hydrolase, tatD family FHJ82_RS00265 ENOG41069ER domain protein FHJ82_RS00275 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) FHJ82_RS00280 ENOG4105XFA sporulation peptidase YabG FHJ82_RS00285 ENOG4105W42 Veg protein FHJ82_RS00290 ENOG4105XEW small acid-soluble spore protein FHJ82_RS00295 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) FHJ82_RS00300 ENOG4105DFT pur operon repressor FHJ82_RS00305 ENOG4105KME endoribonuclease L-psp FHJ82_RS00310 ENOG4105K4W Could be involved in septation (By similarity) FHJ82_RS00315 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) FHJ82_RS00320 ENOG4105C5T Phosphoribosyl pyrophosphate synthase FHJ82_RS00325 ENOG4105KW6 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity) FHJ82_RS00340 ENOG4108JA2 transcriptioN-repair coupling factor FHJ82_RS00345 ENOG4108M14 stage v sporulation protein t FHJ82_RS00355 ENOG4108IY2 MazG family FHJ82_RS00360 ENOG41082I2 s4 domain protein FHJ82_RS00365 ENOG4105VYY sporulation protein yabp FHJ82_RS00380 ENOG41060GV RNA binding s1 domain protein FHJ82_RS00410 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) FHJ82_RS00415 ENOG4108UGV hypoxanthine phosphoribosyltransferase FHJ82_RS00420 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) FHJ82_RS00425 ENOG4105CGM Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity) FHJ82_RS00430 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) FHJ82_RS00435 ENOG4107U48 ppic-type peptidyL-prolyl cis-trans isomerase FHJ82_RS00440 ENOG4105C6T cysteine synthase FHJ82_RS00445 ENOG4105CRQ synthase (Component I) FHJ82_RS00450 ENOG4105DDQ anthranilate synthase FHJ82_RS00455 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 FHJ82_RS00460 ENOG4105EEI dihydropteroate synthase FHJ82_RS00465 ENOG4105KRF dihydroneopterin aldolase FHJ82_RS00470 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase FHJ82_RS00480 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) FHJ82_RS00485 ENOG4105CRK lysyL-tRNA synthetase FHJ82_RS00570 ENOG4108Z0C Uvrb UvrC protein FHJ82_RS00575 ENOG41066A3 ATP guanido phosphotransferase FHJ82_RS00585 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) FHJ82_RS00590 ENOG4105E59 Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity) FHJ82_RS00595 ENOG4105CTP PilT protein domain protein FHJ82_RS00600 ENOG4108QHG Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) FHJ82_RS00605 ENOG4108UH8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity) FHJ82_RS00610 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) FHJ82_RS00615 ENOG4105D7W serine acetyltransferase FHJ82_RS00625 ENOG4105KEB Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) FHJ82_RS00630 ENOG4105C2N RNA methyltransferase TrmH family group 3 FHJ82_RS00635 ENOG4105M0M Tetracycline resistance protein FHJ82_RS00655 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) FHJ82_RS00670 ENOG4108VZM 50s ribosomal protein L10 FHJ82_RS00680 ENOG4107Y49 methyltransferase FHJ82_RS00685 ENOG4108IIJ DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) FHJ82_RS00690 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) FHJ82_RS00695 ENOG4105XPM ribosomal protein FHJ82_RS00700 ENOG4108UKE Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity) FHJ82_RS00705 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) FHJ82_RS00710 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) FHJ82_RS00715 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) FHJ82_RS00720 ENOG4107SKW Inherit from COG: Alpha beta hydrolase FHJ82_RS00725 ENOG4108Z10 Involved in the binding of tRNA to the ribosomes (By similarity) FHJ82_RS00730 ENOG4105EEE One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity) FHJ82_RS00735 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) FHJ82_RS00745 ENOG4105CFD One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity FHJ82_RS00760 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) FHJ82_RS00775 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal FHJ82_RS00790 ENOG4105CW6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits FHJ82_RS00800 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) FHJ82_RS00805 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) FHJ82_RS00810 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) FHJ82_RS00815 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) FHJ82_RS00825 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) FHJ82_RS00830 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) FHJ82_RS00835 ENOG4105CC8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) FHJ82_RS00840 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) FHJ82_RS00855 ENOG41067V7 50S ribosomal protein L36 FHJ82_RS00860 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits FHJ82_RS00865 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) FHJ82_RS00870 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) FHJ82_RS00875 ENOG4108ZT0 50S ribosomal protein l17 FHJ82_RS00880 ENOG4108JJB ABC transporter FHJ82_RS00885 ENOG4108JJB ABC transporter FHJ82_RS00890 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) FHJ82_RS00895 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) FHJ82_RS00900 ENOG4108UM5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity) FHJ82_RS00905 ENOG4108UJD 30S ribosomal protein S9 FHJ82_RS00910 ENOG4108I0C methyltransferase FHJ82_RS00930 ENOG4105D1F ATP-binding protein FHJ82_RS00945 ENOG4108NMV polysaccharide deacetylase FHJ82_RS01010 ENOG4108JPW Aminotransferase FHJ82_RS01020 ENOG4105CPQ Dehydrogenase FHJ82_RS01025 ENOG4105CHH sulfate transporter FHJ82_RS01035 ENOG4108SA1 esterase FHJ82_RS01055 ENOG410874W AraC family transcriptional regulator FHJ82_RS01060 ENOG4105EHZ conserved protein UCP016719 FHJ82_RS01065 ENOG4105D17 glycoside hydrolase, family 3 domain protein FHJ82_RS01080 ENOG4105E15 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate FHJ82_RS01090 ENOG4105EWC Purine nucleoside phosphorylase FHJ82_RS01120 ENOG4105EMN RNA polymerase sigma factor FHJ82_RS01130 ENOG4105C8B TIGR00159 family FHJ82_RS01135 ENOG4107U5W ybbr family FHJ82_RS01140 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) FHJ82_RS01170 ENOG4105BZU Histidine kinase FHJ82_RS01175 ENOG4105C19 ABC transporter FHJ82_RS01200 ENOG41067MG lrgb family FHJ82_RS01210 ENOG41061AU MarR family Transcriptional regulator FHJ82_RS01225 ENOG4105BZU Histidine kinase FHJ82_RS01230 ENOG4105WH1 Two component transcriptional regulator luxr family FHJ82_RS01235 ENOG4105CJ1 ABC, transporter FHJ82_RS01260 ENOG4106DDH Sporulation-specific SASP protein FHJ82_RS01275 ENOG4107QTZ amino acid FHJ82_RS01280 ENOG4105NUN Orthopoxvirus protein of unknown function (DUF830) FHJ82_RS01295 ENOG4107VXM glycerophosphoryl diester phosphodiesterase FHJ82_RS01300 ENOG4105CXY transporter FHJ82_RS01335 ENOG41065RQ ADP-ribosylation crystallin J1 FHJ82_RS01340 ENOG4106BHF FHJ82_RS01350 ENOG4107SCQ Iron-containing alcohol dehydrogenase FHJ82_RS01355 ENOG4108HH9 Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR FHJ82_RS01360 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase FHJ82_RS01365 ENOG4107ZTW SNARE associated Golgi FHJ82_RS01380 ENOG4105C72 UPF0176 protein FHJ82_RS01390 ENOG4105CM2 brancheD-chain amino acid aminotransferase FHJ82_RS01395 ENOG4108IQI permease FHJ82_RS01400 ENOG4108J5H Homocysteine s-methyltransferase FHJ82_RS01410 ENOG4105CSV Glutaminase FHJ82_RS01440 ENOG41076HS cation diffusion facilitator family transporter FHJ82_RS01445 ENOG4108TVJ Nitroreductase FHJ82_RS01450 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase FHJ82_RS01455 ENOG4108VGI doxx family FHJ82_RS01460 ENOG4105XXY Thioredoxin FHJ82_RS01480 ENOG4105DGI Alkaline phosphatase FHJ82_RS01485 ENOG41067S4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) FHJ82_RS01490 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) FHJ82_RS01495 ENOG4108KN7 Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity) FHJ82_RS01500 ENOG4107EPV Aminotransferase class V FHJ82_RS01505 ENOG4105C0R drug resistance transporter emrb qaca subfamily FHJ82_RS01510 ENOG4105J7D transcriptional regulator FHJ82_RS01515 ENOG4107RB3 L-asparaginase FHJ82_RS01520 ENOG4108KTS Acetyltransferase and hydrolase with the alpha beta hydrolase fold FHJ82_RS01525 ENOG41060AI SEC-C motif FHJ82_RS01560 ENOG4105H9W Short-chain dehydrogenase reductase Sdr FHJ82_RS01570 ENOG4105DSE periplasmic solute binding protein FHJ82_RS01575 ENOG4105DIK (ABC) transporter FHJ82_RS01585 ENOG4105DEN Luciferase family FHJ82_RS01590 ENOG4108N0M stress protein FHJ82_RS01595 ENOG4106FN3 tellurium resistance protein FHJ82_RS01600 ENOG4106FN3 tellurium resistance protein FHJ82_RS01605 ENOG4107TS3 membrane protein, TerC FHJ82_RS01610 ENOG4108TTB tellurium resistance protein FHJ82_RS01620 ENOG41079KZ Major Facilitator Superfamily FHJ82_RS01625 ENOG4108IJ7 Glycine betaine FHJ82_RS01630 ENOG4107SQ8 Glycine betaine FHJ82_RS01660 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) FHJ82_RS01690 ENOG4105EIG urea carboxylase-associated protein 1 FHJ82_RS01695 ENOG4107RA1 nh(3)-dependent nad( ) synthetase FHJ82_RS01705 ENOG4105I1F Resistance protein FHJ82_RS01710 ENOG4108WBH protein TIM barrel FHJ82_RS01715 ENOG4105DJB Major Facilitator Superfamily FHJ82_RS01720 ENOG4107Z3Y Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) FHJ82_RS01725 ENOG4105I82 acetyl xylan esterase FHJ82_RS01730 ENOG410756H nucleotidyltransferase FHJ82_RS01740 ENOG4105C26 Dehydrogenase FHJ82_RS01745 ENOG4105CK7 Sodium proline symporter FHJ82_RS01750 ENOG4107YHD transcriptional regulator FHJ82_RS01755 ENOG4105CAY ferredoxin--nadp reductase FHJ82_RS01760 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) FHJ82_RS01765 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit FHJ82_RS01770 ENOG4108IFG nitrite reductase, (NAD(P)H) FHJ82_RS01775 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) FHJ82_RS01790 ENOG4105CKI cobalamin synthesis protein FHJ82_RS01795 ENOG4105E2A Dehydrogenase FHJ82_RS01800 ENOG4105HHM rdd domain containing protein FHJ82_RS01810 ENOG4105CS2 ec 3.2.1.21 FHJ82_RS01830 ENOG41080HJ 6-phospho 3-hexuloisomerase FHJ82_RS01835 ENOG4108VA3 3-hexulose-6-phosphate synthase FHJ82_RS01840 ENOG4105KVH Transcriptional regulator FHJ82_RS01845 ENOG4105CEY Amp-dependent synthetase and ligase FHJ82_RS01865 ENOG4105CAA catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity) FHJ82_RS01880 ENOG4105CDA abc transporter atp-binding protein FHJ82_RS01885 ENOG4105DRP amino acid AbC transporter FHJ82_RS01895 ENOG4106P55 Transcriptional regulator FHJ82_RS01900 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase FHJ82_RS01905 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) FHJ82_RS01910 ENOG41069ZX FHJ82_RS01915 ENOG41069ZX FHJ82_RS01920 ENOG4105DUX Transporter FHJ82_RS01935 ENOG4105E1K spore germination protein FHJ82_RS01960 ENOG4105EAB amino acid AbC transporter FHJ82_RS01965 ENOG4108HW4 amino acid AbC transporter FHJ82_RS01980 ENOG4108PGP mmge prpd family protein FHJ82_RS01990 ENOG4107WD8 ABC transporter, permease FHJ82_RS01995 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FHJ82_RS02000 ENOG4105BZU Histidine kinase FHJ82_RS02020 ENOG4105CFH Aspartokinase FHJ82_RS02025 ENOG4105DHS permease protein FHJ82_RS02030 ENOG4105CM4 permease protein FHJ82_RS02035 ENOG4108IPW abc transporter atp-binding protein FHJ82_RS02050 ENOG4105R8C Transcriptional regulator FHJ82_RS02055 ENOG4108DBC nitroreductase FHJ82_RS02060 ENOG41067V3 Antibiotic biosynthesis monooxygenase FHJ82_RS02065 ENOG4105YVS arsR family transcriptional regulator FHJ82_RS02075 ENOG4108JPW Aminotransferase FHJ82_RS02080 ENOG4105C26 Dehydrogenase FHJ82_RS02090 ENOG4105H9W Short-chain dehydrogenase reductase Sdr FHJ82_RS02095 ENOG4105KTB nuclear export factor GLE1 FHJ82_RS02100 ENOG4108T5E Copper resistance protein FHJ82_RS02105 ENOG4108ZYE Transcriptional regulator FHJ82_RS02125 ENOG4107SQ3 mannitol-1-phosphate 5-dehydrogenase FHJ82_RS02145 ENOG4105E7W lamb ycsf family protein FHJ82_RS02150 ENOG4105C5A transporter FHJ82_RS02155 ENOG4105CFM UPF0317 protein FHJ82_RS02160 ENOG4105P4J Allophanate hydrolase, subunit 1 FHJ82_RS02170 ENOG4107258 Transcriptional regulator FHJ82_RS02175 ENOG4105XJB lipolytic protein G-D-S-L family FHJ82_RS02185 ENOG41061CK Antibiotic biosynthesis monooxygenase FHJ82_RS02190 ENOG4107RVG penicillin-binding protein FHJ82_RS02195 ENOG4107QM2 Aldo Keto reductase FHJ82_RS02200 ENOG4105ETD TRANSCRIPTIONal FHJ82_RS02210 ENOG4105CYX Short-chain dehydrogenase reductase Sdr FHJ82_RS02225 ENOG410606W general stress protein FHJ82_RS02235 ENOG4105VCH membrane FHJ82_RS02245 ENOG4105C9U ATP-dependent DNA helicase RecQ FHJ82_RS02260 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) FHJ82_RS02265 ENOG4107R8N Glycosyl transferase, family 2 FHJ82_RS02275 ENOG4105C0X amino acid FHJ82_RS02335 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) FHJ82_RS02345 ENOG4105NRR Uncharacterized protein conserved in bacteria (DUF2188) FHJ82_RS02350 ENOG4105RXJ FHJ82_RS02355 ENOG4105KPY Small multidrug resistance protein FHJ82_RS02360 ENOG4105EU9 FHJ82_RS02365 ENOG4105QVS general stress protein FHJ82_RS02370 ENOG41082W1 Cupin 2, conserved barrel domain protein FHJ82_RS02385 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit FHJ82_RS02390 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism FHJ82_RS02395 ENOG4108MRH transcriptional regulatory protein FHJ82_RS02405 ENOG4106F5Q Membrane FHJ82_RS02410 ENOG4105CJ1 ABC, transporter FHJ82_RS02425 ENOG4105FDT acyl-CoA dehydrogenase FHJ82_RS02445 ENOG4105SZ6 Thioredoxin FHJ82_RS02450 ENOG4105CPF Cell wall formation (By similarity) FHJ82_RS02455 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) FHJ82_RS02460 ENOG4105C1J atp-dependent rna helicase FHJ82_RS02465 ENOG410905X membrane-flanked domain protein FHJ82_RS02470 ENOG4105CKV Membrane FHJ82_RS02480 ENOG4107ZSJ Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity) FHJ82_RS02485 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein FHJ82_RS02490 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) FHJ82_RS02500 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) FHJ82_RS02505 ENOG4107MMM Anti-sigma-factor antagonist FHJ82_RS02510 ENOG4105FUA antagonist FHJ82_RS02515 ENOG4105QD0 anti-sigma regulatory factor serine threonine protein kinase FHJ82_RS02520 ENOG4107SGM protein serine threonine phosphatase FHJ82_RS02525 ENOG4105WN5 stage II sporulation protein FHJ82_RS02530 ENOG4108ZBE Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity) FHJ82_RS02540 ENOG41064BQ Phosphatase FHJ82_RS02555 ENOG410906U SprT-like FHJ82_RS02630 ENOG4105CSH Transporter FHJ82_RS02635 ENOG4105K56 Transcriptional regulator FHJ82_RS02645 ENOG4108ZMQ domain protein FHJ82_RS02660 ENOG4108Z40 Transcriptional regulator FHJ82_RS02665 ENOG4108RYK Nad-dependent epimerase dehydratase FHJ82_RS02680 ENOG4105VEQ Cold shock protein FHJ82_RS02690 ENOG4105XTG Pfam:DUF156 FHJ82_RS02695 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase FHJ82_RS02700 ENOG4105C72 UPF0176 protein FHJ82_RS02705 ENOG4105VFE sira family FHJ82_RS02710 ENOG4107TPS domain protein FHJ82_RS02715 ENOG4105VFE sira family FHJ82_RS02720 ENOG41087NI Sulfite exporter TauE/SafE FHJ82_RS02740 ENOG4105IRW patatin-like phospholipase family protein FHJ82_RS02750 ENOG41082W1 Cupin 2, conserved barrel domain protein FHJ82_RS02765 ENOG4105DNP FAD linked oxidase domain protein FHJ82_RS02775 ENOG4105PGM cation diffusion facilitator family transporter FHJ82_RS02780 ENOG4105H3G oxidoreductase FHJ82_RS02790 ENOG4108VK3 Cupin 2 Conserved Barrel Domain Protein FHJ82_RS02830 ENOG4105DQ4 alcohol dehydrogenase FHJ82_RS02835 ENOG4105VUF Transcriptional regulator FHJ82_RS02845 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FHJ82_RS02860 ENOG4105EQ0 Major Facilitator superfamily FHJ82_RS02865 ENOG4108JGH Tetr family transcriptional regulator FHJ82_RS02870 ENOG4105T38 integral membrane protein FHJ82_RS02875 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FHJ82_RS02890 ENOG4105E2A Dehydrogenase FHJ82_RS02895 ENOG4105PGS Spore coat protein FHJ82_RS02905 ENOG4105ENE Histidine kinase FHJ82_RS02910 ENOG4108VB1 regulatoR FHJ82_RS02915 ENOG4105EYF MMPL domain protein FHJ82_RS02935 ENOG4108JYZ YitT family FHJ82_RS02945 ENOG4105C2C drug resistance transporter, Bcr CflA FHJ82_RS02950 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) FHJ82_RS02970 ENOG41090E6 transcriptional regulator MERR family FHJ82_RS02985 ENOG4105F2W methyltransferase FHJ82_RS02990 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) FHJ82_RS02995 ENOG4105DRR Transcriptional regulator, GntR family FHJ82_RS03015 ENOG4105FQP Beta-lactamase FHJ82_RS03025 ENOG41090UD (LipO)protein FHJ82_RS03030 ENOG4108SUT Major Facilitator Superfamily FHJ82_RS03035 ENOG4108TZY GntR Family Transcriptional Regulator FHJ82_RS03040 ENOG4105JXH GntR family transcriptional regulator FHJ82_RS03045 ENOG4105DJ2 Major Facilitator Superfamily FHJ82_RS03125 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) FHJ82_RS03130 ENOG4105K8N protein family UPF0079, ATPase FHJ82_RS03135 ENOG41072GX Peptidase M22 Glycoprotease FHJ82_RS03140 ENOG410801F ribosomal-protein-alanine acetyltransferase FHJ82_RS03145 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) FHJ82_RS03150 ENOG4105C5H ABC transporter FHJ82_RS03155 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) FHJ82_RS03160 ENOG4105FF6 Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity) FHJ82_RS03165 ENOG41067S4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) FHJ82_RS03170 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) FHJ82_RS03180 ENOG4108TYN CAAX amino terminal protease family protein FHJ82_RS03190 ENOG4105CJ9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity) FHJ82_RS03220 ENOG4105PGZ NB-ARC domain FHJ82_RS03225 ENOG4105CPQ Dehydrogenase FHJ82_RS03230 ENOG4105CT4 transporter FHJ82_RS03245 ENOG41087YS Phage shock protein A FHJ82_RS03250 ENOG4105DQX Zinc finger domain FHJ82_RS03255 ENOG4108WV1 Pfam:DUF477 FHJ82_RS03265 ENOG4105EXC Acyl-transferase FHJ82_RS03270 ENOG4108P49 AntiSigma factor FHJ82_RS03275 ENOG4105JVQ RNA Polymerase FHJ82_RS03300 ENOG4107STQ Multicopper oxidase FHJ82_RS03305 ENOG4105C85 amino acid FHJ82_RS03310 ENOG4105C7R Atpase associated with various cellular activities aaa_3 FHJ82_RS03325 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) FHJ82_RS03345 ENOG4105C7N Xanthine uracil vitamin C permease FHJ82_RS03370 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) FHJ82_RS03375 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit FHJ82_RS03380 ENOG4105C83 adenylosuccinate lyase FHJ82_RS03385 ENOG4105C8V SAICAR synthetase FHJ82_RS03390 ENOG4105VR9 phosphoribosylformylglycinamidine synthase FHJ82_RS03395 ENOG4105D21 Phosphoribosylformylglycinamidine synthase I FHJ82_RS03400 ENOG4108JIU phosphoribosylformylglycinamidine synthase ii FHJ82_RS03410 ENOG4105CXB phosphoribosylaminoimidazole synthetase FHJ82_RS03415 ENOG4108V3E phosphoribosylglycinamide formyltransferase FHJ82_RS03425 ENOG4105C12 Phosphoribosylglycinamide synthetase FHJ82_RS03440 ENOG4108R5T secreted protein FHJ82_RS03445 ENOG4105KGF protein, YerC YecD FHJ82_RS03450 ENOG4105CBC glutamate synthase FHJ82_RS03460 ENOG4105C4R Atp-dependent dna helicase FHJ82_RS03465 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) FHJ82_RS03475 ENOG4105CRN Aminoglycoside phosphotransferase FHJ82_RS03480 ENOG4105KT7 mgtC SapB transporter FHJ82_RS03485 ENOG4105CK7 Sodium proline symporter FHJ82_RS03490 ENOG4105VB5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) FHJ82_RS03495 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) FHJ82_RS03500 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) FHJ82_RS03505 ENOG4108IG5 Transcriptional regulator FHJ82_RS03515 ENOG4105CBD Diacylglycerol kinase FHJ82_RS03520 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) FHJ82_RS03530 ENOG4105CJ1 ABC, transporter FHJ82_RS03575 ENOG4105CDY transcriptional regulatory protein FHJ82_RS03585 ENOG41075D4 Aminoglycoside 6-adenylyltransferase FHJ82_RS03600 ENOG4105WEF catalase FHJ82_RS03605 ENOG4105M18 -acetyltransferase FHJ82_RS03615 ENOG4105H67 Protein of unknown function (DUF421) FHJ82_RS03620 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) FHJ82_RS03625 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FHJ82_RS03645 ENOG4106I4J membrane FHJ82_RS03650 ENOG41082F9 transcriptional regulator FHJ82_RS03655 ENOG41061H0 Monooxygenase FHJ82_RS03660 ENOG4108R1P FHJ82_RS03665 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) FHJ82_RS03670 ENOG4105E0M Sulfatase FHJ82_RS03675 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase FHJ82_RS03685 ENOG41090R9 glycosyltransferase FHJ82_RS03690 ENOG4107R51 Glycosyl transferase, family 2 FHJ82_RS03695 ENOG41090R9 glycosyltransferase FHJ82_RS03700 ENOG4105EU0 Major facilitator Superfamily FHJ82_RS03705 ENOG4105CUB amino acid FHJ82_RS03710 ENOG4105C26 Dehydrogenase FHJ82_RS03715 ENOG4105FKZ Methyl-accepting chemotaxis FHJ82_RS03720 ENOG4105CYX Short-chain dehydrogenase reductase Sdr FHJ82_RS03725 ENOG4107TVC Glycosyl transferase, family 2 FHJ82_RS03730 ENOG4105C5H ABC transporter FHJ82_RS03735 ENOG4107SWG transcriptional regulator MERR family FHJ82_RS03740 ENOG4105DXB Major Facilitator superfamily FHJ82_RS03745 ENOG4105C5H ABC transporter FHJ82_RS03750 ENOG4105FDU atp-dependent rna helicase FHJ82_RS03760 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein FHJ82_RS03775 ENOG4108J20 pectate lyase FHJ82_RS03780 ENOG4107QPK )-transporter FHJ82_RS03805 ENOG4108MRH transcriptional regulatory protein FHJ82_RS03830 ENOG41084X4 Acylphosphatase (EC 3.6.1.7) FHJ82_RS03835 ENOG4108RPX mosc domain containing protein FHJ82_RS03855 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) FHJ82_RS03895 ENOG4105C5Y PTS System FHJ82_RS03900 ENOG4105CG3 alpha amylase, catalytic region FHJ82_RS03905 ENOG4107414 GntR family transcriptional regulator FHJ82_RS03910 ENOG4108RCM Nitroreductase FHJ82_RS03925 ENOG4105CGH 5'-nucleotidase FHJ82_RS03930 ENOG4107RKG DJ-1/PfpI family FHJ82_RS03935 ENOG4105ETE Transcriptional regulator (LacI family FHJ82_RS03945 ENOG4105FF2 Type I DHQase FHJ82_RS03960 ENOG4105KJF protein tyrosine phosphatase FHJ82_RS03970 ENOG4107U9T Pfam:Ribonuclease_BN FHJ82_RS03975 ENOG4108ISG Major Facilitator FHJ82_RS03980 ENOG4105UPD Calcium Proton FHJ82_RS03990 ENOG4105D8X mechanosensitive ion channel FHJ82_RS04025 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FHJ82_RS04035 ENOG4106KE4 Dehydrogenase FHJ82_RS04045 ENOG4105D7N magnesium and cobalt transport protein CorA FHJ82_RS04055 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) FHJ82_RS04080 ENOG4107RUY (E1 component), alpha subunit FHJ82_RS04090 ENOG4107QKR Dehydrogenase FHJ82_RS04100 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family FHJ82_RS04110 ENOG4105F8D glycoside hydrolase family 4 FHJ82_RS04115 ENOG4108Q3X Transcriptional regulator FHJ82_RS04120 ENOG4105CI1 PTS System FHJ82_RS04130 ENOG4105BZ1 (ABC) transporter FHJ82_RS04135 ENOG4105BZ1 (ABC) transporter FHJ82_RS04145 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase FHJ82_RS04150 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) FHJ82_RS04155 ENOG4105U3E Transcriptional regulator FHJ82_RS04160 ENOG4105DYS nad(p)h dehydrogenase (quinone) FHJ82_RS04165 ENOG4105H93 Acyltransferase family FHJ82_RS04180 ENOG4108YYS metal-dependent hydrolase (By similarity) FHJ82_RS04185 ENOG4105C0R drug resistance transporter emrb qaca subfamily FHJ82_RS04190 ENOG410834F Transcriptional regulator FHJ82_RS04200 ENOG4105JAB phenazine biosynthesis protein, phzf family FHJ82_RS04205 ENOG4107Y03 Nitroreductase FHJ82_RS04220 ENOG4105ECP epimerase FHJ82_RS04225 ENOG410902V Modulates RecA activity (By similarity) FHJ82_RS04235 ENOG4105F27 Major Facilitator FHJ82_RS04245 ENOG4108TCS Glutamyl endopeptidase FHJ82_RS04265 ENOG4106AKJ FHJ82_RS04270 ENOG4105D74 hydrolase FHJ82_RS04275 ENOG4105CKK Glycosyl transferase, family 2 FHJ82_RS04280 ENOG4105EJV Membrane FHJ82_RS04285 ENOG41067AE Membrane-bound metal-dependent hydrolase FHJ82_RS04290 ENOG4105CEN a g-specific adenine glycosylase FHJ82_RS04295 ENOG4106BXE FHJ82_RS04300 ENOG4105CAN Short-chain dehydrogenase reductase Sdr FHJ82_RS04320 ENOG4105BZ1 (ABC) transporter FHJ82_RS04325 ENOG4107NBY Membrane FHJ82_RS04330 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase FHJ82_RS04335 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FHJ82_RS04340 ENOG4105G5W regulator Fur family FHJ82_RS04345 ENOG4105TUA UPF0295 protein FHJ82_RS04455 ENOG4105EC3 peptidase S51, dipeptidase E FHJ82_RS04460 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) FHJ82_RS04465 ENOG4105DNP FAD linked oxidase domain protein FHJ82_RS04475 ENOG4105DEF Extracellular solute-binding protein, family 5 FHJ82_RS04485 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FHJ82_RS04490 ENOG4105C3U ABC transporter FHJ82_RS04495 ENOG4108JQ7 (ABC) transporter FHJ82_RS04510 ENOG4105E2Y ABC, transporter FHJ82_RS04515 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein FHJ82_RS04520 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component FHJ82_RS04530 ENOG41082QR Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity) FHJ82_RS04535 ENOG4107D63 FHJ82_RS04540 ENOG4105VZ8 Transcriptional regulator FHJ82_RS04555 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) FHJ82_RS04565 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) FHJ82_RS04585 ENOG4105CYN Serine protein kinase FHJ82_RS04595 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes FHJ82_RS04600 ENOG4105CW7 secretion protein, HlyD family FHJ82_RS04605 ENOG4105C0R drug resistance transporter emrb qaca subfamily FHJ82_RS04610 ENOG4105CS1 NAD(P)H quinone oxidoreductase FHJ82_RS04625 ENOG4108TU7 Inherit from COG: (ABC) transporter FHJ82_RS04630 ENOG4105VEQ Cold shock protein FHJ82_RS04640 ENOG4105BZU Histidine kinase FHJ82_RS04680 ENOG4108YBP pseudouridine synthase FHJ82_RS04690 ENOG41080XP Cbs domain FHJ82_RS04695 ENOG4107YBY Hydrolase FHJ82_RS04700 ENOG4105DGM nitrilase cyanide hydratase and apolipoprotein n-acyltransferase FHJ82_RS04705 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FHJ82_RS04710 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator FHJ82_RS04720 ENOG4108HMR Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) FHJ82_RS04725 ENOG4105C6V Glycerol-3-phosphate dehydrogenase FHJ82_RS04735 ENOG4105BZU Histidine kinase FHJ82_RS04740 ENOG4105WH1 Two component transcriptional regulator luxr family FHJ82_RS04775 ENOG4105ED1 spovr family FHJ82_RS04780 ENOG4105G6Z alkaline phosphatase FHJ82_RS04795 ENOG4105BZN citrate synthase FHJ82_RS04800 ENOG4105CYX Short-chain dehydrogenase reductase Sdr FHJ82_RS04805 ENOG4105CUB amino acid FHJ82_RS04810 ENOG4105C8J )-transporter FHJ82_RS04820 ENOG4105J37 FHJ82_RS04825 ENOG4108AEY RNA polymerase sigma factor FHJ82_RS04830 ENOG4105F6E Acyl-transferase FHJ82_RS04835 ENOG4105C37 (CBS) domain FHJ82_RS04845 ENOG4105CHM Aminotransferase FHJ82_RS04850 ENOG4108MH3 Polyketide beta-ketoacyl acyl carrier protein synthase FHJ82_RS04855 ENOG4105C37 (CBS) domain FHJ82_RS04865 ENOG4105WMR Protein CrcB homolog FHJ82_RS04870 ENOG4108QXE glycerophosphoryl diester phosphodiesterase FHJ82_RS04880 ENOG4105D64 Mechanosensitive ion channel FHJ82_RS04885 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) FHJ82_RS04890 ENOG4107VMI polysaccharide deacetylase FHJ82_RS04895 ENOG4105F0I Aminotransferase FHJ82_RS04900 ENOG4105W1N transcriptional regulator FHJ82_RS04905 ENOG4105IIP Membrane FHJ82_RS04915 ENOG4105BZ1 (ABC) transporter FHJ82_RS04920 ENOG4105BZ1 (ABC) transporter FHJ82_RS04940 ENOG410839P FHJ82_RS04950 ENOG4106MP8 UPF0754 membrane protein FHJ82_RS04955 ENOG4105WZB UPF0342 protein FHJ82_RS04960 ENOG4105F1N DNA alkylation repair FHJ82_RS04970 ENOG4105D4P Coproporphyrinogen iii oxidase FHJ82_RS04980 ENOG4107S91 Sodium hydrogen exchanger FHJ82_RS04985 ENOG4105NCW Trka-c domain protein FHJ82_RS04995 ENOG4105CGU Enoyl-CoA hydratase FHJ82_RS05005 ENOG4108IUX (ABC) transporter FHJ82_RS05010 ENOG4105RHA ABC transporter, permease FHJ82_RS05015 ENOG4107VRP DNA repair exonuclease FHJ82_RS05020 ENOG4106D4I domain protein FHJ82_RS05025 ENOG4105EQI Metal Dependent Phosphohydrolase FHJ82_RS05035 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) FHJ82_RS05080 ENOG4105NBU tryptophan transport protein FHJ82_RS05085 ENOG4105DXJ Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) FHJ82_RS05090 ENOG4105K59 histidine triad (HIT) protein FHJ82_RS05120 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation FHJ82_RS05125 ENOG4105BZ4 penicillin-binding protein FHJ82_RS05130 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) FHJ82_RS05135 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) FHJ82_RS05140 ENOG4105C1Q protoporphyrinogen oxidase FHJ82_RS05150 ENOG4105ECB domain protein FHJ82_RS05165 ENOG4105DER m42 family FHJ82_RS05175 ENOG4106AXD FHJ82_RS05180 ENOG4108RQ5 Beta-lactamase domain-containing protein FHJ82_RS05185 ENOG4105DF9 Lipoate-protein, ligase FHJ82_RS05195 ENOG4105CEY Amp-dependent synthetase and ligase FHJ82_RS05205 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 FHJ82_RS05220 ENOG4108HUF Transporter FHJ82_RS05225 ENOG4107TB6 phosphoglycerate mutase FHJ82_RS05235 ENOG4107F3J Amp-dependent synthetase and ligase FHJ82_RS05240 ENOG4107ZYJ bioY protein FHJ82_RS05245 ENOG4106YBV Methyl-accepting chemotaxis FHJ82_RS05265 ENOG4105XVF Competence transcription factor FHJ82_RS05275 ENOG4108ZMX Domain of unknown function (DU1801) FHJ82_RS05285 ENOG4105X3H Excalibur domain protein FHJ82_RS05290 ENOG4105K8R UPF0145 protein FHJ82_RS05295 ENOG4105E1V na solute symporter FHJ82_RS05300 ENOG4106CAD Protein of unknown function (DUF3311) FHJ82_RS05305 ENOG41060YP FHJ82_RS05320 ENOG4107SCK Monooxygenase FHJ82_RS05325 ENOG4108INS Transcriptional regulator FHJ82_RS05330 ENOG4108KK1 membrane protein AbrB duplication FHJ82_RS05340 ENOG4108IG5 Transcriptional regulator FHJ82_RS05350 ENOG4108QY0 Membrane FHJ82_RS05355 ENOG4105C5N The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination FHJ82_RS05360 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation FHJ82_RS05370 ENOG4105EYH Exonuclease FHJ82_RS05415 ENOG4105ERH Fumarylacetoacetate hydrolase FHJ82_RS05430 ENOG4105CAQ asparagine synthetase FHJ82_RS05440 ENOG4105UQX Mate efflux family protein FHJ82_RS05445 ENOG4106HBX Transcriptional Regulator AraC Family FHJ82_RS05455 ENOG4105SF0 DinB family FHJ82_RS05460 ENOG4108ZUB Lysine exporter protein (Lyse ygga) FHJ82_RS05465 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FHJ82_RS05470 ENOG4105MYW Pentapeptide repeat protein FHJ82_RS05475 ENOG4105MA6 gCN5-related N-acetyltransferase FHJ82_RS05485 ENOG4108VPT UPF0234 protein FHJ82_RS05490 ENOG4105QNR S1 RNA binding domain protein FHJ82_RS05495 ENOG4105DIH basic membrane FHJ82_RS05500 ENOG4105C8Q Methyl-accepting chemotaxis FHJ82_RS05505 ENOG4107E6A Cytochrome p-450 FHJ82_RS05515 ENOG4105EPR degv family FHJ82_RS05520 ENOG4107AYK membrAne FHJ82_RS05530 ENOG41073B9 FHJ82_RS05540 ENOG4108KP7 hydrolase FHJ82_RS05545 ENOG4108MXZ Esterase FHJ82_RS05550 ENOG4105VG1 fes assembly suf system protein FHJ82_RS05555 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) FHJ82_RS05560 ENOG4105IQ5 FAD linked oxidase domain protein FHJ82_RS05570 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase FHJ82_RS05575 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) FHJ82_RS05580 ENOG4105CAS nag kinase FHJ82_RS05585 ENOG4105C8Y Acetylornithine aminotransferase FHJ82_RS05590 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain FHJ82_RS05600 ENOG4105DBV ornithine carbamoyltransferase FHJ82_RS05625 ENOG4107RMD Basic membrane lipoprotein FHJ82_RS05640 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) FHJ82_RS05645 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) FHJ82_RS05655 ENOG4105C3U ABC transporter FHJ82_RS05660 ENOG4108JQ7 (ABC) transporter FHJ82_RS05675 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FHJ82_RS05685 ENOG4105C31 Tryptophanyl-tRNA synthetase FHJ82_RS05690 ENOG4108J59 Extracellular solute-binding protein, family 5 FHJ82_RS05695 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FHJ82_RS05700 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FHJ82_RS05710 ENOG4108JQ7 (ABC) transporter FHJ82_RS05725 ENOG41090SU Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity) FHJ82_RS05730 ENOG4108ZCF integral membrane protein FHJ82_RS05735 ENOG4108SQ7 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis FHJ82_RS05745 ENOG4105DPN Oligoendopeptidase f FHJ82_RS05755 ENOG4105T58 Dithiol-disulfide isomerase FHJ82_RS05760 ENOG4108Z18 K06886 hemoglobin FHJ82_RS05765 ENOG4105E4C Lytic transglycosylase catalytic FHJ82_RS05770 ENOG4105MIX Adenylate cyclase FHJ82_RS05785 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) FHJ82_RS05790 ENOG4105EMS pseudouridine synthase FHJ82_RS05795 ENOG4107S1Q Phosphatase FHJ82_RS05805 ENOG4105ETU transcriptional activator (TenA FHJ82_RS05810 ENOG4108VEU Thiamine monophosphate synthase FHJ82_RS05830 ENOG4105D06 uba thif-type nad fad binding protein FHJ82_RS05835 ENOG4105DWF phosphomethylpyrimidine kinase FHJ82_RS05840 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH FHJ82_RS05845 ENOG4107A88 FHJ82_RS05895 ENOG4105ENA helicase FHJ82_RS05915 ENOG4105CJ1 ABC, transporter FHJ82_RS05930 ENOG4108ZMI UPF0477 protein FHJ82_RS05940 ENOG4105C28 cystathionine FHJ82_RS05945 ENOG4105C28 cystathionine FHJ82_RS05985 ENOG4105Z0X Glyoxalase Bleomycin resistance protein (Dioxygenase FHJ82_RS06000 ENOG4105C0R drug resistance transporter emrb qaca subfamily FHJ82_RS06015 ENOG4105CKN UDP-glucose-hexose-1-phosphate uridylyltransferase FHJ82_RS06020 ENOG4105CMR udp-glucose 4-epimerase FHJ82_RS06025 ENOG4105CRD Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity) FHJ82_RS06030 ENOG4105CK1 PTS System FHJ82_RS06035 ENOG4105VCP PTS System FHJ82_RS06045 ENOG4105E98 transcriptional regulator DeoR family FHJ82_RS06065 ENOG4105KT7 mgtC SapB transporter FHJ82_RS06090 ENOG4108IEG Formate dehydrogenase Alpha subunit FHJ82_RS06100 ENOG4106A3M Cytochrome p-450 FHJ82_RS06105 ENOG41087PP glycosyltransferase MGT family FHJ82_RS06115 ENOG4105EXQ uroporphyrinogen iii synthase hem4 FHJ82_RS06120 ENOG4105C4B ABC transporter, permease FHJ82_RS06125 ENOG4108IXI (ABC) transporter FHJ82_RS06135 ENOG4105Q95 Cupin 2, conserved barrel domain protein FHJ82_RS06150 ENOG4105D2H Uronic isomerase FHJ82_RS06155 ENOG4105CT4 transporter FHJ82_RS06160 ENOG4107KJX Transcriptional regulator FHJ82_RS06165 ENOG4107QZW Altronate oxidoreductase FHJ82_RS06170 ENOG4105CTX dehydratase FHJ82_RS06180 ENOG4105F3H Histidine kinase FHJ82_RS06200 ENOG4105BZU Histidine kinase FHJ82_RS06220 ENOG4108JJA ABC, transporter FHJ82_RS06235 ENOG4107TSN permease FHJ82_RS06255 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase FHJ82_RS06260 ENOG4105KWG Pfam:DUF1696 FHJ82_RS06265 ENOG4105K7W phage-related replication protein FHJ82_RS06270 ENOG410635T phage-like element pbsx protein FHJ82_RS06315 ENOG4108TFU terminase (Small subunit) FHJ82_RS06325 ENOG4108MDF Phage Portal Protein FHJ82_RS06350 ENOG41060SN FHJ82_RS06365 ENOG4105PQS phage protein FHJ82_RS06370 ENOG4105FR7 XkdM protein, phage-like element PBSX FHJ82_RS06375 ENOG4105MTC XkdN-like protein FHJ82_RS06385 ENOG4108FKH Transglycosylase SLT domain FHJ82_RS06385 ENOG4108FKH Transglycosylase SLT domain FHJ82_RS06385 ENOG4108FKH Transglycosylase SLT domain FHJ82_RS06390 ENOG4108WZM domain protein FHJ82_RS06395 ENOG4105X7F FHJ82_RS06405 ENOG4105MFU Protein of unknown function (DUF2634) FHJ82_RS06410 ENOG41066EA baseplate J family protein FHJ82_RS06415 ENOG410906S phage-like element pbsx protein xkdt FHJ82_RS06425 ENOG41068G1 FHJ82_RS06455 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase FHJ82_RS06470 ENOG4105CJ3 phosphate transporter FHJ82_RS06475 ENOG4107GRR phosphate transport regulator FHJ82_RS06480 ENOG4107R7I amino acid FHJ82_RS06490 ENOG4105EDW glycosyl transferase, family 39 FHJ82_RS06495 ENOG4105CKK Glycosyl transferase, family 2 FHJ82_RS06505 ENOG4105C0H protease FHJ82_RS06515 ENOG4108ME1 Peptidase M55 D-aminopeptidase FHJ82_RS06520 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FHJ82_RS06525 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FHJ82_RS06540 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A FHJ82_RS06545 ENOG4105DTQ mandelate racemase muconate lactonizing FHJ82_RS06550 ENOG4107SN7 NLP P60 protein FHJ82_RS06555 ENOG4108JQ7 (ABC) transporter FHJ82_RS06560 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) FHJ82_RS06565 ENOG4107TUM Amidinotransferase FHJ82_RS06570 ENOG4108S4H thioesterase Superfamily protein FHJ82_RS06575 ENOG4108428 Inherit from COG: -acetyltransferase FHJ82_RS06585 ENOG41080TC multidrug resistance protein FHJ82_RS06590 ENOG4105CIY formyltetrahydrofolate deformylase FHJ82_RS06595 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) FHJ82_RS06610 ENOG4105K56 Transcriptional regulator FHJ82_RS06615 ENOG4108ZHJ Organic hydroperoxide resistance protein FHJ82_RS06630 ENOG4107TVC Glycosyl transferase, family 2 FHJ82_RS06645 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) FHJ82_RS06650 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin FHJ82_RS06660 ENOG4108W7F transporter, permease FHJ82_RS06665 ENOG4108JJB ABC transporter FHJ82_RS06670 ENOG4105NSK ABC superfamily ATP binding cassette transporter membrane protein FHJ82_RS06675 ENOG4105VRS hydrolase family 18 FHJ82_RS06690 ENOG4105CJW magnesium transporter FHJ82_RS06695 ENOG4105V75 Transcriptional regulator FHJ82_RS06725 ENOG4105FDF Could be involved in DNA repair (By similarity) FHJ82_RS06735 ENOG4107T5V SNARE associated Golgi FHJ82_RS06740 ENOG4107TS3 membrane protein, TerC FHJ82_RS06745 ENOG4108WZW RNA polymerase sigma FHJ82_RS06755 ENOG410681C small acid-soluble spore protein FHJ82_RS06765 ENOG4105D0M Protease HtpX homolog FHJ82_RS06775 ENOG410900G Protein of unknown function (DUF421) FHJ82_RS06785 ENOG4108TGC Acyltransferase FHJ82_RS06790 ENOG4105BZU Histidine kinase FHJ82_RS06795 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FHJ82_RS06800 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) FHJ82_RS06810 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase FHJ82_RS06820 ENOG4105DT1 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate FHJ82_RS06825 ENOG4105JAS Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene) (By similarity) FHJ82_RS06830 ENOG4107QY0 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) FHJ82_RS06835 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) FHJ82_RS06845 ENOG4105BZU Histidine kinase FHJ82_RS06850 ENOG41090MY MarR family Transcriptional regulator FHJ82_RS06855 ENOG4105ER2 Ompa motb domain protein FHJ82_RS06860 ENOG4105E14 MotA TolQ exbB proton channel FHJ82_RS06870 ENOG4108K88 Membrane FHJ82_RS06880 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) FHJ82_RS06885 ENOG4107ZAE 6-carboxy-5,6,7,8-tetrahydropterin synthase FHJ82_RS06890 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) FHJ82_RS06895 ENOG4105CSD Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity) FHJ82_RS06910 ENOG4105CBZ Short-chain dehydrogenase reductase Sdr FHJ82_RS06935 ENOG4105F0V Cell wall hydrolase FHJ82_RS06950 ENOG4105C59 p-type ATPase FHJ82_RS06955 ENOG4105DC7 peptidase M24 FHJ82_RS06965 ENOG4105CID antiterminator FHJ82_RS06975 ENOG4105KRI phosphocarrier protein (HPr FHJ82_RS06980 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) FHJ82_RS06990 ENOG4105F6S Spore photoproduct lyase FHJ82_RS06995 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FHJ82_RS07000 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FHJ82_RS07005 ENOG4105K4I Scp-like extracellular FHJ82_RS07015 ENOG4105BZU Histidine kinase FHJ82_RS07020 ENOG4105CHM Aminotransferase FHJ82_RS07035 ENOG4105UIN FHJ82_RS07045 ENOG4107Y2H ErfK ybiS ycfS ynhG family protein FHJ82_RS07065 ENOG4105EPM Diguanylate phosphodiesterase FHJ82_RS07075 ENOG4108XRC Protein of unknown function (DUF458) FHJ82_RS07105 ENOG4105NQC Flavodoxin FHJ82_RS07125 ENOG4105D8X mechanosensitive ion channel FHJ82_RS07130 ENOG4107R19 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FHJ82_RS07145 ENOG41082CS Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) FHJ82_RS07150 ENOG4105D06 uba thif-type nad fad binding protein FHJ82_RS07155 ENOG4105CVM Molybdenum cofactor synthesis domain protein FHJ82_RS07160 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein FHJ82_RS07165 ENOG4108ZAF Molybdopterin FHJ82_RS07170 ENOG41067WU Molybdopterin converting factor (Subunit 1) FHJ82_RS07180 ENOG4107X8C Efflux transporter RND family MFP subunit FHJ82_RS07185 ENOG4105C19 ABC transporter FHJ82_RS07190 ENOG4107RBB ABC transporter, permease FHJ82_RS07195 ENOG4105E98 transcriptional regulator DeoR family FHJ82_RS07200 ENOG4105DE4 1-phosphofructokinase FHJ82_RS07205 ENOG4105DM4 PTS System FHJ82_RS07220 ENOG4105C5H ABC transporter FHJ82_RS07225 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) FHJ82_RS07250 ENOG4105BZU Histidine kinase FHJ82_RS07260 ENOG4107ZYR domain protein FHJ82_RS07265 ENOG4105CPN adenine deaminase FHJ82_RS07270 ENOG4105CN5 Metallo-Beta-Lactamase FHJ82_RS07275 ENOG4106148 UPF0356 protein FHJ82_RS07280 ENOG4108X4Q Hydrolase FHJ82_RS07285 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) FHJ82_RS07300 ENOG4107QKG PfaD family FHJ82_RS07305 ENOG4105C0W non-ribosomal peptide synthetase FHJ82_RS07310 ENOG4107SQU synthase FHJ82_RS07315 ENOG4105C0W non-ribosomal peptide synthetase FHJ82_RS07320 ENOG4107SQU synthase FHJ82_RS07325 ENOG4107SQU synthase FHJ82_RS07330 ENOG4107SQU synthase FHJ82_RS07340 ENOG4105FQP Beta-lactamase FHJ82_RS07350 ENOG4105CPP Dehydrogenase, E1 component FHJ82_RS07355 ENOG4105C7S Dehydrogenase FHJ82_RS07380 ENOG4105CXN decarboxylase FHJ82_RS07385 ENOG4105WBI UPF0223 protein FHJ82_RS07400 ENOG4105ECY inositol monophosphatase FHJ82_RS07410 ENOG4105D4Y metalloprotease FHJ82_RS07435 ENOG4105CI3 gtp-binding protein typa FHJ82_RS07440 ENOG4105QA2 FHJ82_RS07455 ENOG4108IAB Phoh family FHJ82_RS07465 ENOG4105CSV Glutaminase FHJ82_RS07475 ENOG4105CNI cell division protein FtsW FHJ82_RS07480 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) FHJ82_RS07490 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) FHJ82_RS07500 ENOG4105BZ9 Cytochrome C oxidase, subunit I FHJ82_RS07505 ENOG4105CCU oxidase (Subunit III) FHJ82_RS07510 ENOG41064X9 cytochrome C oxidase subunit IV FHJ82_RS07525 ENOG41080XQ Signal transduction protein with cbs domains FHJ82_RS07530 ENOG4106UY4 Inherit from COG: Scp-like extracellular FHJ82_RS07555 ENOG4106H78 methyltransferase FHJ82_RS07560 ENOG4108ZEF Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity) FHJ82_RS07565 ENOG4105H20 Sporulation integral membrane protein YlbJ FHJ82_RS07570 ENOG4105D78 K07001 NTE family protein FHJ82_RS07575 ENOG41063PX domain protein FHJ82_RS07585 ENOG4105KNH Nucleic acid-binding protein FHJ82_RS07615 ENOG4108V6E Cell division protein mraZ FHJ82_RS07620 ENOG4105CGJ Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity) FHJ82_RS07630 ENOG4105CJN penicillin-binding protein FHJ82_RS07635 ENOG4105CJN penicillin-binding protein FHJ82_RS07640 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) FHJ82_RS07645 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) FHJ82_RS07650 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) FHJ82_RS07655 ENOG4105CNI cell division protein FtsW FHJ82_RS07660 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) FHJ82_RS07665 ENOG4105D4A Cell wall formation (By similarity) FHJ82_RS07670 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) FHJ82_RS07675 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) FHJ82_RS07680 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) FHJ82_RS07690 ENOG4105FFI sigma-e processing peptidase spoiiga FHJ82_RS07695 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FHJ82_RS07705 ENOG4105DKW ABC transporter FHJ82_RS07715 ENOG4105WR5 sporulation protein, YlmC YmxH family FHJ82_RS07720 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase FHJ82_RS07725 ENOG4105DFA alanine racemase domain protein FHJ82_RS07730 ENOG4105VR5 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity) FHJ82_RS07735 ENOG41067XK integral membrane protein FHJ82_RS07740 ENOG4105DBK s4 domain protein FHJ82_RS07750 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) FHJ82_RS07760 ENOG4105M02 This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) FHJ82_RS07765 ENOG4105C34 Pseudouridine synthase FHJ82_RS07770 ENOG4108UK1 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity) FHJ82_RS07780 ENOG4105CXT aspartate transcarbamylase FHJ82_RS07790 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain FHJ82_RS07795 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain FHJ82_RS07800 ENOG4105DF0 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity) FHJ82_RS07805 ENOG4107RY0 Catalyzes the conversion of dihydroorotate to orotate (By similarity) FHJ82_RS07815 ENOG41065E1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) FHJ82_RS07830 ENOG4107RIQ Sulfate adenylate transferase FHJ82_RS07840 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) FHJ82_RS07850 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein FHJ82_RS07865 ENOG4105DSJ YicC domain protein FHJ82_RS07870 ENOG4105KC4 UPF0296 protein FHJ82_RS07875 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) FHJ82_RS07885 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase FHJ82_RS07890 ENOG4105C25 Primosomal protein n' FHJ82_RS07895 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) FHJ82_RS07900 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) FHJ82_RS07905 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B FHJ82_RS07910 ENOG4105C55 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs FHJ82_RS07915 ENOG4108ZF3 Phosphatase FHJ82_RS07920 ENOG4105D9P serine threonine protein kinase FHJ82_RS07925 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) FHJ82_RS07930 ENOG4105DJV ribulose-phosphate 3-epimerase FHJ82_RS07935 ENOG4105FJ0 thiamine FHJ82_RS07945 ENOG4105VB9 50S ribosomal protein l28 FHJ82_RS07950 ENOG4108ZAA Alkaline-shock protein FHJ82_RS07955 ENOG4105DP4 dak2 domain fusion protein ylov FHJ82_RS07965 ENOG4105EJQ L-serine dehydratase FHJ82_RS07970 ENOG4105CB5 ATP-dependent DNA helicase recG FHJ82_RS07975 ENOG4108VVV Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism (By similarity) FHJ82_RS07980 ENOG4105C6B Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity) FHJ82_RS07985 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase FHJ82_RS07990 ENOG4105CHR reductase FHJ82_RS08000 ENOG4108ZBM Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) FHJ82_RS08005 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) FHJ82_RS08010 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) FHJ82_RS08020 ENOG4105VBN Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity) FHJ82_RS08030 ENOG4105K5M 30s ribosomal protein S16 FHJ82_RS08035 ENOG4108BW8 UPF0109 protein FHJ82_RS08050 ENOG4105D6X Specifically methylates guanosine-37 in various tRNAs (By similarity) FHJ82_RS08055 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) FHJ82_RS08060 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) FHJ82_RS08065 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) FHJ82_RS08075 ENOG4105VM1 flagellar FHJ82_RS08080 ENOG4105CMV Succinyl-CoA synthetase subunit beta FHJ82_RS08085 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha FHJ82_RS08090 ENOG4105C79 DNA protecting protein DprA FHJ82_RS08095 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) FHJ82_RS08100 ENOG4107QXI Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity) FHJ82_RS08105 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FHJ82_RS08110 ENOG4108R5P Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity) FHJ82_RS08115 ENOG4105C4N this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity) FHJ82_RS08125 ENOG4105Q75 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) FHJ82_RS08130 ENOG4108ZC9 flagellar basal-body rod protein flgc FHJ82_RS08135 ENOG4105VQ0 flagellar hook-basal body complex protein fliE FHJ82_RS08140 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) FHJ82_RS08145 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) FHJ82_RS08160 ENOG4106YF4 Flagellar biosynthesis chaperone FHJ82_RS08170 ENOG410696Y Flagellar hook-length control protein FHJ82_RS08175 ENOG410822I Flagellar hook capping protein FHJ82_RS08180 ENOG4108JQA flagellar FHJ82_RS08185 ENOG41068WV flagellar FlbD family protein FHJ82_RS08195 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) FHJ82_RS08200 ENOG4105DD5 Flagellar motor switch protein FHJ82_RS08205 ENOG4107YTP response regulator receiver protein FHJ82_RS08215 ENOG4105CN7 Flagellar biosynthetic protein FliP FHJ82_RS08220 ENOG4105VS8 Flagellar biosynthetic protein fliq FHJ82_RS08225 ENOG4105D19 Role in flagellar biosynthesis (By similarity) FHJ82_RS08230 ENOG4105D00 flagellar biosynthetic protein flhB FHJ82_RS08235 ENOG4105D7B Flagellar biosynthesis protein flha FHJ82_RS08240 ENOG4105FZW flagellar biosynthesis regulator FlhF FHJ82_RS08250 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) FHJ82_RS08255 ENOG4105CBS Chea signal transduction histidine kinase FHJ82_RS08260 ENOG410807Z Modulation of CheA activity in response to attractants (Chemotaxis FHJ82_RS08270 ENOG4108Z4W Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity) FHJ82_RS08275 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FHJ82_RS08285 ENOG4105CE9 30S ribosomal protein S2 FHJ82_RS08295 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) FHJ82_RS08300 ENOG4108VCV Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) FHJ82_RS08305 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) FHJ82_RS08310 ENOG4105KNE Phosphatidate cytidylyltransferase FHJ82_RS08320 ENOG4105DZP Membrane-associated zinc metalloprotease FHJ82_RS08325 ENOG4105C90 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity) FHJ82_RS08330 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) FHJ82_RS08335 ENOG4105K7D Required for maturation of 30S ribosomal subunits (By similarity) FHJ82_RS08340 ENOG4105CHV Transcription elongation factor NusA FHJ82_RS08345 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination FHJ82_RS08350 ENOG4105VHM ribosomal protein FHJ82_RS08355 ENOG4107EEM One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity) FHJ82_RS08360 ENOG4105W7A Protein of unknown function (DUF503) FHJ82_RS08365 ENOG4105KG7 Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity) FHJ82_RS08370 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) FHJ82_RS08375 ENOG4105DTN riboflavin biosynthesis protein ribF FHJ82_RS08380 ENOG4105K77 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity) FHJ82_RS08385 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) FHJ82_RS08395 ENOG4105C1V Peptidase, M16 FHJ82_RS08405 ENOG4105E35 Dipicolinate synthase subunit A FHJ82_RS08410 ENOG4108S0H Dipicolinic acid synthetase, b subunit FHJ82_RS08415 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) FHJ82_RS08425 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FHJ82_RS08435 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit FHJ82_RS08445 ENOG4105CNU cell division protein FtsK FHJ82_RS08450 ENOG4105FDP GntR family transcriptional regulator FHJ82_RS08465 ENOG4105EYF MMPL domain protein FHJ82_RS08480 ENOG4108RKS Short-chain dehydrogenase reductase Sdr FHJ82_RS08485 ENOG4105XZV Protein of unknown function (DUF3243) FHJ82_RS08500 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase FHJ82_RS08505 ENOG4105CEV competence damage-inducible protein FHJ82_RS08510 ENOG4105C68 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity) FHJ82_RS08515 ENOG4108A04 Beta-lactamase FHJ82_RS08525 ENOG4105D48 metallophosphoesterase FHJ82_RS08530 ENOG4105MCT stage V sporulation protein S FHJ82_RS08535 ENOG4105CPQ Dehydrogenase FHJ82_RS08540 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) FHJ82_RS08545 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) FHJ82_RS08565 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) FHJ82_RS08575 ENOG4108151 Beta-lactamase domain protein FHJ82_RS08580 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase FHJ82_RS08585 ENOG4108JA1 polyketide synthase FHJ82_RS08590 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase FHJ82_RS08595 ENOG41062T2 Acyl carrier protein FHJ82_RS08600 ENOG4105F99 Hydroxymethylglutaryl-CoA synthase FHJ82_RS08605 ENOG4108MGH Enoyl-CoA hydratase FHJ82_RS08610 ENOG4108KQ6 Enoyl-CoA hydratase FHJ82_RS08615 ENOG4105C0W non-ribosomal peptide synthetase FHJ82_RS08620 ENOG4107SQU synthase FHJ82_RS08630 ENOG4105C0W non-ribosomal peptide synthetase FHJ82_RS08640 ENOG4106A3M Cytochrome p-450 FHJ82_RS08645 ENOG4105WFK nuclease FHJ82_RS08650 ENOG4105XPP Protein of unknown function (DUF1275) FHJ82_RS08660 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin FHJ82_RS08670 ENOG4105K7W phage-related replication protein FHJ82_RS08675 ENOG4108X3M OsmC Ohr family protein FHJ82_RS08700 ENOG4105DKX Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity) FHJ82_RS08725 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FHJ82_RS08730 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FHJ82_RS08735 ENOG4105U6W MutT NUDIX family protein FHJ82_RS08740 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase FHJ82_RS08750 ENOG4106F1P AAA ATPase, central domain protein FHJ82_RS08755 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) FHJ82_RS08760 ENOG4105CXI aluminum resistance protein FHJ82_RS08765 ENOG4105KV4 Transcriptional regulator FHJ82_RS08770 ENOG4105C5F glutamine synthetase FHJ82_RS08795 ENOG41064BW Protein of unknown function (DUF2568) FHJ82_RS08810 ENOG4105CT4 transporter FHJ82_RS08825 ENOG4105C93 Xylose Isomerase FHJ82_RS08830 ENOG4105CMG Carbohydrate kinase FHJ82_RS08835 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) FHJ82_RS08860 ENOG4105DQ4 alcohol dehydrogenase FHJ82_RS08865 ENOG4105MXK Carbon dioxide concentrating mechanism protein FHJ82_RS08910 ENOG4108M1A Chitin-binding protein FHJ82_RS08935 ENOG4107YUK This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) FHJ82_RS08940 ENOG4105K7W phage-related replication protein FHJ82_RS08965 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) FHJ82_RS08980 ENOG4105VPS UPF0291 protein FHJ82_RS08985 ENOG4105CV1 Transketolase (EC 2.2.1.1) FHJ82_RS08995 ENOG4105VXM UPF0154 protein FHJ82_RS09005 ENOG4107QIV Cytochrome c biogenesis protein FHJ82_RS09040 ENOG4108I0Z Aconitate hydratase FHJ82_RS09045 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FHJ82_RS09060 ENOG41067CD Small, acid-soluble spore protein Tlp FHJ82_RS09070 ENOG4105MI2 FHJ82_RS09075 ENOG4105W8X HesB YadR YfhF-family protein FHJ82_RS09080 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) FHJ82_RS09085 ENOG4105K4P CoA-binding domain protein FHJ82_RS09090 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FHJ82_RS09115 ENOG4105CPQ Dehydrogenase FHJ82_RS09120 ENOG4108UHU Aldolase FHJ82_RS09125 ENOG4105CHZ Catalyzes the dehydration of D-mannonate (By similarity) FHJ82_RS09130 ENOG4105DMW Dehydrogenase reductase FHJ82_RS09140 ENOG4108I5G Major Facilitator superfamily FHJ82_RS09155 ENOG4105FVX FHJ82_RS09190 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FHJ82_RS09200 ENOG4107SYN Glycosyl hydrolases family 43 FHJ82_RS09225 ENOG4105DTD Dehydrogenase FHJ82_RS09230 ENOG4108IIH CoA-transferase subunit B FHJ82_RS09235 ENOG4105D6N CoA-transferase, subunit a FHJ82_RS09240 ENOG4105CY2 Citrate transporter FHJ82_RS09245 ENOG4106A3M Cytochrome p-450 FHJ82_RS09250 ENOG4105CZF Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) FHJ82_RS09255 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) FHJ82_RS09260 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) FHJ82_RS09265 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FHJ82_RS09270 ENOG4108W8G Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP (By similarity) FHJ82_RS09285 ENOG4107T5V SNARE associated Golgi FHJ82_RS09290 ENOG4107QX3 carboxylase FHJ82_RS09295 ENOG4105E39 Enoyl-CoA hydratase FHJ82_RS09300 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase FHJ82_RS09305 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit FHJ82_RS09310 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase FHJ82_RS09315 ENOG4105CEY Amp-dependent synthetase and ligase FHJ82_RS09320 ENOG4105C1G acyl-Coa dehydrogenase FHJ82_RS09325 ENOG4105F32 YngK protein FHJ82_RS09330 ENOG4106U2H Protein of unknown function (DUF1360) FHJ82_RS09340 ENOG4105CEY Amp-dependent synthetase and ligase FHJ82_RS09345 ENOG4105CEY Amp-dependent synthetase and ligase FHJ82_RS09350 ENOG4105C0W non-ribosomal peptide synthetase FHJ82_RS09360 ENOG4105C0W non-ribosomal peptide synthetase FHJ82_RS09365 ENOG4107RVU D-Ala-D-Ala carboxypeptidase 3 (S13) family FHJ82_RS09370 ENOG4108N2V aldose 1-epimerase FHJ82_RS09375 ENOG4107QJQ Mate efflux family protein FHJ82_RS09400 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) FHJ82_RS09405 ENOG4108RWP Major Facilitator Superfamily protein FHJ82_RS09410 ENOG4105WAB arsR family transcriptional regulator FHJ82_RS09415 ENOG4105C22 threonyL-tRNA synthetase FHJ82_RS09420 ENOG4108KSA LysR family transcriptional regulator FHJ82_RS09425 ENOG4105CB2 alcohol dehydrogenase FHJ82_RS09430 ENOG4105BZ8 glutamate synthase FHJ82_RS09435 ENOG4105CBC glutamate synthase FHJ82_RS09440 ENOG4105C5Q Transcriptional regulator FHJ82_RS09445 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) FHJ82_RS09470 ENOG4108UB7 FHJ82_RS09475 ENOG4105IE8 Alpha-ketoglutarate permease FHJ82_RS09480 ENOG4107U6E carbohydrate kinase FGGY FHJ82_RS09485 ENOG4108M3J Dehydrogenase FHJ82_RS09490 ENOG4108J2R molybdopterin oxidoreductase FHJ82_RS09515 ENOG4106ANW SMI1_KNR4 FHJ82_RS09520 ENOG4106BHF FHJ82_RS09525 ENOG4108Z7R Chaperone CsaA FHJ82_RS09530 ENOG4105FTV AraC Family Transcriptional Regulator FHJ82_RS09540 ENOG4108W8B Beta-lactamase domain protein FHJ82_RS09550 ENOG4105KTU Transcriptional regulator, arsr family FHJ82_RS09560 ENOG4108SJC Membrane FHJ82_RS09585 ENOG41069ER domain protein FHJ82_RS09590 ENOG4105C9U ATP-dependent DNA helicase RecQ FHJ82_RS09600 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) FHJ82_RS09605 ENOG4105SCY DNAK suppressor FHJ82_RS09650 ENOG4105C26 Dehydrogenase FHJ82_RS09655 ENOG4105EWU Squalene--hopene cyclase FHJ82_RS09660 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FHJ82_RS09665 ENOG4105C8J )-transporter FHJ82_RS09670 ENOG4105C09 Bile acid FHJ82_RS09680 ENOG4105C7S Dehydrogenase FHJ82_RS09685 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 FHJ82_RS09690 ENOG4107T89 von Willebrand factor, type A FHJ82_RS09695 ENOG4105GMT ATPase associated with various cellular activities aaa_5 FHJ82_RS09705 ENOG4105K4H Nlp p60 protein FHJ82_RS09710 ENOG41087PP glycosyltransferase MGT family FHJ82_RS09720 ENOG4107QMU Mate efflux family protein FHJ82_RS09725 ENOG4106SCS STAS domain FHJ82_RS09745 ENOG4105FR1 rard protein FHJ82_RS09760 ENOG41090U3 tautomerase FHJ82_RS09780 ENOG4105FBA Phospholipase Carboxylesterase FHJ82_RS09795 ENOG4105E1V na solute symporter FHJ82_RS09805 ENOG4105CS2 ec 3.2.1.21 FHJ82_RS09810 ENOG4108S3Y transcriptional regulator FHJ82_RS09830 ENOG4108VXD carboxy-peptidase FHJ82_RS09835 ENOG4105D3A purine nucleoside phosphorylase DeoD-type FHJ82_RS09845 ENOG4106Z5R FHJ82_RS09850 ENOG410841Q phosphoesterase PA-phosphatase related protein FHJ82_RS09880 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein FHJ82_RS09885 ENOG4108TSC N-acetyltransferase FHJ82_RS09890 ENOG4107S4Y M20 DapE family protein YgeY FHJ82_RS09905 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FHJ82_RS09910 ENOG4105FTQ Dna gyrase FHJ82_RS10010 ENOG4106ANW SMI1_KNR4 FHJ82_RS10015 ENOG4106BHF FHJ82_RS10025 ENOG4107Y9E nuclease FHJ82_RS10040 ENOG4105E0X reductase FHJ82_RS10045 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) FHJ82_RS10055 ENOG4105QZP Uncharacterized protein conserved in bacteria (DUF2140) FHJ82_RS10060 ENOG41090WU lipolytic protein G-D-S-L family FHJ82_RS10065 ENOG4108KF3 Electron transport protein SCO1 SenC FHJ82_RS10075 ENOG4105C7B Threonine dehydratase FHJ82_RS10085 ENOG4108UT2 hemolysin iii FHJ82_RS10095 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) FHJ82_RS10100 ENOG4105C0V Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity) FHJ82_RS10110 ENOG4107YX5 Pfam:DUF548 FHJ82_RS10115 ENOG4108Y6J UPF0403 protein FHJ82_RS10120 ENOG4105C01 Dihydroxy-acid dehydratase FHJ82_RS10135 ENOG4108V06 Glutathione peroxidase FHJ82_RS10140 ENOG4105CVG Homoserine O-transsuccinylase FHJ82_RS10185 ENOG41081VK Ribonuclease FHJ82_RS10210 ENOG410890F Dynamin family FHJ82_RS10225 ENOG41065KQ synthase FHJ82_RS10255 ENOG4105C2W permease FHJ82_RS10260 ENOG4108UPS Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity) FHJ82_RS10265 ENOG4105CTD carboxy-peptidase FHJ82_RS10270 ENOG4105DVT helicase FHJ82_RS10285 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) FHJ82_RS10295 ENOG4105XWG Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity) FHJ82_RS10300 ENOG4108UKS UPF0398 protein FHJ82_RS10315 ENOG4107X2U Inherit from COG: Exonuclease-like protein FHJ82_RS10320 ENOG4108I5C dEAD DEAH box helicase FHJ82_RS10365 ENOG4108UI2 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity) FHJ82_RS10370 ENOG4105BZ4 penicillin-binding protein FHJ82_RS10380 ENOG4105CSM endonuclease III FHJ82_RS10390 ENOG4105C5S asparaginyl-tRNA synthetase FHJ82_RS10395 ENOG4105CHM Aminotransferase FHJ82_RS10405 ENOG4105YAC FHJ82_RS10410 ENOG4105DVT helicase FHJ82_RS10415 ENOG4108Z2X Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity) FHJ82_RS10425 ENOG4105CCG Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity) FHJ82_RS10435 ENOG4105D4J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate FHJ82_RS10440 ENOG4105CPK Glycosyl transferase (Group 1 FHJ82_RS10445 ENOG4105FJR Lmbe family FHJ82_RS10450 ENOG4108Z5K methylglyoxal synthase FHJ82_RS10455 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) FHJ82_RS10460 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase FHJ82_RS10465 ENOG4108JYZ YitT family FHJ82_RS10490 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) FHJ82_RS10510 ENOG41068YB TPR repeat-containing protein FHJ82_RS10515 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase FHJ82_RS10525 ENOG4105CIH Imidazole acetol-phosphate transaminase FHJ82_RS10535 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) FHJ82_RS10540 ENOG4108ZGB N-(5'-phosphoribosyl)anthranilate isomerase FHJ82_RS10545 ENOG4105DK0 Indole-3-glycerol phosphate synthase FHJ82_RS10555 ENOG4105CRQ synthase (Component I) FHJ82_RS10560 ENOG4105KHN chorismate mutase FHJ82_RS10570 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase FHJ82_RS10575 ENOG4105BZU Histidine kinase FHJ82_RS10580 ENOG4108UGX Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity) FHJ82_RS10585 ENOG4105EAH synthase FHJ82_RS10590 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) FHJ82_RS10595 ENOG4105XXQ heptaprenyl diphosphate synthase component I FHJ82_RS10600 ENOG4105WP2 Tryptophan RNA-binding attenuator protein FHJ82_RS10605 ENOG4105EUJ GTP cyclohydrolase i FHJ82_RS10610 ENOG4105K70 DNA-binding protein FHJ82_RS10615 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) FHJ82_RS10630 ENOG4105CSF NADPH-dependent glycerol-3-phosphate dehydrogenase FHJ82_RS10635 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) FHJ82_RS10655 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) FHJ82_RS10660 ENOG4105CAT Cytidine monophosphate kinase FHJ82_RS10675 ENOG4105MSI germination protein ypeb FHJ82_RS10685 ENOG4108PNU Involved in the degradation of specific anti-sigma factors (By similarity) FHJ82_RS10690 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase FHJ82_RS10705 ENOG4107RGJ metallophosphoesterase FHJ82_RS10720 ENOG4105I7S Abortive infection protein FHJ82_RS10725 ENOG4105C9U ATP-dependent DNA helicase RecQ FHJ82_RS10730 ENOG4105T7X FHJ82_RS10740 ENOG4108SAX Membrane FHJ82_RS10745 ENOG4108JQ1 Dehydrogenase FHJ82_RS10760 ENOG4105BZU Histidine kinase FHJ82_RS10765 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FHJ82_RS10770 ENOG4105CRE cytochrome C FHJ82_RS10775 ENOG4107TWT Cytochrome c biogenesis protein FHJ82_RS10785 ENOG4105FE9 pseudouridine synthase FHJ82_RS10795 ENOG4108JIC nucleoside recognition domain protein FHJ82_RS10800 ENOG4105DZ1 carboxypeptidase FHJ82_RS10810 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) FHJ82_RS10815 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) FHJ82_RS10835 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) FHJ82_RS10840 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) FHJ82_RS10845 ENOG4108R6K riboflavin synthase, subunit alpha FHJ82_RS10870 ENOG4107ZE5 PPIases accelerate the folding of proteins FHJ82_RS10875 ENOG4105PTM secreted protein FHJ82_RS10880 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) FHJ82_RS10890 ENOG4105G6R Stage v sporulation protein ae FHJ82_RS10900 ENOG4105CZ3 stage V sporulation protein ad FHJ82_RS10905 ENOG41090VF Stage v sporulation protein ac FHJ82_RS10920 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FHJ82_RS10925 ENOG4108ZBE Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity) FHJ82_RS10930 ENOG41082AN stage II sporulation protein FHJ82_RS10935 ENOG4105DZ1 carboxypeptidase FHJ82_RS10940 ENOG4105CB1 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) FHJ82_RS10945 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) FHJ82_RS10950 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FHJ82_RS10960 ENOG4105I3K Ferric uptake regulator, Fur family FHJ82_RS10965 ENOG4105MZ9 stage II sporulation protein m FHJ82_RS10985 ENOG4105DFD Na H antiporter FHJ82_RS10995 ENOG4105HDK L-asparaginase FHJ82_RS11000 ENOG4108IMY Transcriptional regulator FHJ82_RS11010 ENOG4108YZ4 nudix hydrolase FHJ82_RS11020 ENOG4105CPC Aldo Keto reductase FHJ82_RS11040 ENOG4106HZJ FHJ82_RS11045 ENOG4105RHY Pfam:UPF0157 FHJ82_RS11050 ENOG4105KAC Antibiotic biosynthesis monooxygenase FHJ82_RS11055 ENOG4108XET gCN5-related N-acetyltransferase FHJ82_RS11060 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FHJ82_RS11075 ENOG4105C02 permease FHJ82_RS11085 ENOG4105HRU Glyoxalase Bleomycin resistance protein (Dioxygenase FHJ82_RS11090 ENOG4105CS9 pantothenic acid kinase FHJ82_RS11100 ENOG4108IXY short-chain dehydrogenase reductase FHJ82_RS11105 ENOG41069FQ Metallo-beta-lactamase superfamily FHJ82_RS11110 ENOG4105II7 pyrroline-5-carboxylate reductase FHJ82_RS11115 ENOG4108KQ6 Enoyl-CoA hydratase FHJ82_RS11120 ENOG4105F99 Hydroxymethylglutaryl-CoA synthase FHJ82_RS11125 ENOG4106A3M Cytochrome p-450 FHJ82_RS11140 ENOG4105C0W non-ribosomal peptide synthetase FHJ82_RS11145 ENOG4105C0W non-ribosomal peptide synthetase FHJ82_RS11155 ENOG4105C0W non-ribosomal peptide synthetase FHJ82_RS11165 ENOG4105CHR reductase FHJ82_RS11170 ENOG4105CEY Amp-dependent synthetase and ligase FHJ82_RS11185 ENOG4107QKG PfaD family FHJ82_RS11190 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) FHJ82_RS11195 ENOG4108K70 Transcriptional regulator FHJ82_RS11205 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FHJ82_RS11215 ENOG410861F 50S ribosomal protein L33 FHJ82_RS11220 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) FHJ82_RS11225 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase FHJ82_RS11230 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) FHJ82_RS11235 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FHJ82_RS11245 ENOG4107XQC Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity) FHJ82_RS11250 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) FHJ82_RS11255 ENOG4108HNZ carboxyl transferase FHJ82_RS11260 ENOG4108ZVT methylmalonyl-coA epimerase FHJ82_RS11275 ENOG4108QEG Membrane FHJ82_RS11280 ENOG4105CDA abc transporter atp-binding protein FHJ82_RS11285 ENOG4105E5Q amino acid AbC transporter FHJ82_RS11290 ENOG4108HW3 (ABC) transporter FHJ82_RS11295 ENOG4108Y6J UPF0403 protein FHJ82_RS11300 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) FHJ82_RS11305 ENOG4105C7S Dehydrogenase FHJ82_RS11310 ENOG4105CPP Dehydrogenase, E1 component FHJ82_RS11325 ENOG4105CKM Branched-chain carboxylic acid kinase FHJ82_RS11330 ENOG4107RDP Dehydrogenase FHJ82_RS11340 ENOG4108JUB Transcriptional regulator FHJ82_RS11345 ENOG4106CCJ Protein of unknown function (DUF2627) FHJ82_RS11350 ENOG4105CR4 methylisocitrate lyase FHJ82_RS11355 ENOG4105DXD 2-methylcitrate dehydratase FHJ82_RS11365 ENOG4105C1G acyl-Coa dehydrogenase FHJ82_RS11370 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase FHJ82_RS11380 ENOG4108QXE glycerophosphoryl diester phosphodiesterase FHJ82_RS11385 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase FHJ82_RS11410 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FHJ82_RS11425 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) FHJ82_RS11430 ENOG4107QQR Sporulation FHJ82_RS11435 ENOG4105S1Z Stage IV sporulation protein B FHJ82_RS11440 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) FHJ82_RS11445 ENOG4105XBY Regulates arginine biosynthesis genes (By similarity) FHJ82_RS11450 ENOG4105DX0 Hemolysin A FHJ82_RS11455 ENOG4105C2V Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity) FHJ82_RS11460 ENOG4105CTB Polyprenyl synthetase FHJ82_RS11465 ENOG41067QG Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) FHJ82_RS11470 ENOG4105DVS Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) FHJ82_RS11475 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) FHJ82_RS11480 ENOG4105M7K Involved in the transcription termination process (By similarity) FHJ82_RS11485 ENOG4108ZSR alkaline shock protein FHJ82_RS11490 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase FHJ82_RS11510 ENOG410644B Stage III sporulation protein af FHJ82_RS11520 ENOG4105KQ4 Stage iii sporulation protein ad FHJ82_RS11525 ENOG4108CQH stage III sporulation protein AC FHJ82_RS11530 ENOG4105KR5 Stage iii sporulation protein FHJ82_RS11535 ENOG4105CD2 stage iii sporulation protein aa FHJ82_RS11545 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) FHJ82_RS11550 ENOG4105DC7 peptidase M24 FHJ82_RS11560 ENOG4105CBJ Metal-dependent enzyme FHJ82_RS11580 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) FHJ82_RS11585 ENOG4105WZW rhodanese family FHJ82_RS11590 ENOG4107RGW The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor FHJ82_RS11600 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) FHJ82_RS11605 ENOG4105C0D helicase FHJ82_RS11620 ENOG4108IMY Transcriptional regulator FHJ82_RS11630 ENOG4105VFR signal peptidase FHJ82_RS11690 ENOG4105C37 (CBS) domain FHJ82_RS11715 ENOG4105C5X domain protein FHJ82_RS11760 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase FHJ82_RS11775 ENOG41068DG YceG-like family FHJ82_RS11780 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) FHJ82_RS11785 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) FHJ82_RS11790 ENOG4105E2Z phosphate ABC transporter (Permease FHJ82_RS11795 ENOG4105C8U phosphate abc transporter FHJ82_RS11800 ENOG4105CVA phosphate FHJ82_RS11805 ENOG4107RF6 penicillin-binding protein FHJ82_RS11815 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FHJ82_RS11820 ENOG4105SXS Protein of unknown function (DUF456) FHJ82_RS11835 ENOG4105C4E Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity) FHJ82_RS11840 ENOG41063Y9 FHJ82_RS11845 ENOG4108U5J '-nucleotidase FHJ82_RS11850 ENOG4105N80 Ferric uptake regulator, Fur family FHJ82_RS11855 ENOG4108JYZ YitT family FHJ82_RS11860 ENOG41069ZM Protein of unknown function (DUF2624) FHJ82_RS11865 ENOG4105EFU Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity) FHJ82_RS11880 ENOG4108IUH Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity) FHJ82_RS11885 ENOG4105EGD dinuclear metal center protein, YbgI family FHJ82_RS11900 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FHJ82_RS11905 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) FHJ82_RS11910 ENOG4108UPT UPF0178 protein FHJ82_RS11915 ENOG4105CF9 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity) FHJ82_RS11925 ENOG4105C38 Glycyl-tRNA synthetase beta subunit FHJ82_RS11930 ENOG4108HMW glycyl-tRNA synthetase, alpha subunit FHJ82_RS11935 ENOG4106DBE Involved in DNA repair and RecF pathway recombination (By similarity) FHJ82_RS11945 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) FHJ82_RS11950 ENOG4105KG3 cytidine deaminase FHJ82_RS11955 ENOG4107YR5 Diacylglycerol kinase FHJ82_RS11960 ENOG4105KGE Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity) FHJ82_RS11965 ENOG4105CTJ Metal Dependent Phosphohydrolase FHJ82_RS11970 ENOG4105C9A Phoh family FHJ82_RS11975 ENOG4105EI1 sporulation protein yqfd FHJ82_RS11980 ENOG41068P3 sporulation protein YqfC FHJ82_RS11990 ENOG4105DI5 UPF0365 protein FHJ82_RS11995 ENOG4105F7J membrane-bound serine protease FHJ82_RS12000 ENOG4105KTH gatB Yqey FHJ82_RS12015 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) FHJ82_RS12020 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) FHJ82_RS12025 ENOG4105F59 Methylates ribosomal protein L11 (By similarity) FHJ82_RS12030 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) FHJ82_RS12035 ENOG4105CFG Acts as a chaperone (By similarity) FHJ82_RS12040 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ FHJ82_RS12045 ENOG4105CI8 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity) FHJ82_RS12050 ENOG4105CSA Coproporphyrinogen iii oxidase FHJ82_RS12055 ENOG4105C4S Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity) FHJ82_RS12065 ENOG4108ZRV stage ii sporulation protein p FHJ82_RS12070 ENOG4105CEF Initiates the rapid degradation of small, acid-soluble proteins during spore germination (By similarity) FHJ82_RS12075 ENOG4105KQV Binds directly to 16S ribosomal RNA (By similarity) FHJ82_RS12080 ENOG4105TQK DNA polymerase iii, delta' subunit FHJ82_RS12095 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 FHJ82_RS12100 ENOG4108UK2 deaminase FHJ82_RS12105 ENOG4105KQC Competence protein FHJ82_RS12115 ENOG4108D32 Methyltransferase FHJ82_RS12125 ENOG4108WF2 Metal Dependent Phosphohydrolase FHJ82_RS12130 ENOG4108Z1W Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity) FHJ82_RS12135 ENOG410812S Rna-binding protein FHJ82_RS12140 ENOG4105E2X shikimate dehydrogenase FHJ82_RS12145 ENOG4105CQW ribosome biogenesis GTPase YqeH FHJ82_RS12150 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase FHJ82_RS12170 ENOG41080BT SNARE associated Golgi FHJ82_RS12185 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FHJ82_RS12210 ENOG4105KVH Transcriptional regulator FHJ82_RS12285 ENOG4108SWU Histidine kinase FHJ82_RS12290 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FHJ82_RS12295 ENOG4105DHF Membrane FHJ82_RS12305 ENOG4108UYN gCN5-related N-acetyltransferase FHJ82_RS12310 ENOG4105KR8 Inherit from COG: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) FHJ82_RS12320 ENOG4108J8C transporter major facilitator family protein FHJ82_RS12330 ENOG4108U7W acetyltransferase FHJ82_RS12345 ENOG4108HCJ Hydrolase FHJ82_RS12350 ENOG4108HCJ Hydrolase FHJ82_RS12360 ENOG4105DG6 mannose-6-phosphate isomerase FHJ82_RS12365 ENOG4105DM4 PTS System FHJ82_RS12380 ENOG4108Z66 YbaK ebsC protein FHJ82_RS12385 ENOG4107RSM transcriptional regulator FHJ82_RS12390 ENOG4105D94 Major Facilitator Superfamily FHJ82_RS12395 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) FHJ82_RS12400 ENOG41082JN Transcriptional regulator FHJ82_RS12420 ENOG4105TMB Formate nitrite transporter FHJ82_RS12425 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) FHJ82_RS12430 ENOG4108JB9 formate dehydrogenase FHJ82_RS12445 ENOG4105C28 cystathionine FHJ82_RS12475 ENOG4107XRG penicillin-binding protein FHJ82_RS12480 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) FHJ82_RS12490 ENOG4105CFP Peptidase U32 FHJ82_RS12495 ENOG4105XYU peptidase (U32 family) FHJ82_RS12505 ENOG4105HHA aminodeoxychorismate lyase FHJ82_RS12515 ENOG4108Z08 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) FHJ82_RS12520 ENOG4105VBH UPF0297 protein FHJ82_RS12525 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) FHJ82_RS12530 ENOG4105C02 permease FHJ82_RS12535 ENOG4105CDA abc transporter atp-binding protein FHJ82_RS12540 ENOG4105CT1 (ABC) transporter FHJ82_RS12545 ENOG4105EAD ABC transporter FHJ82_RS12550 ENOG4105DRP amino acid AbC transporter FHJ82_RS12560 ENOG41060CR FHJ82_RS12570 ENOG4105C7H Helicase, RecD TraA family FHJ82_RS12580 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) FHJ82_RS12585 ENOG4105C3J Cysteine desulfurase FHJ82_RS12595 ENOG4105D1H recombination factor protein RarA FHJ82_RS12600 ENOG4105CUZ uba thif-type nad fad binding protein FHJ82_RS12610 ENOG4105C9M aspartyl-trna synthetase FHJ82_RS12615 ENOG4105CUT histidyl-tRNA synthetase FHJ82_RS12650 ENOG41067VP Protein of unknown function (DUF1049) FHJ82_RS12655 ENOG4105NCW Trka-c domain protein FHJ82_RS12670 ENOG4105CKP Polysaccharide Biosynthesis Protein FHJ82_RS12675 ENOG4108QG2 Membrane FHJ82_RS12680 ENOG4105NAP FHJ82_RS12685 ENOG4105VIE preprotein translocase, subunit YajC FHJ82_RS12690 ENOG4105C6U Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity) FHJ82_RS12695 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) FHJ82_RS12700 ENOG41061AI Protein of unknown function (DUF2905) FHJ82_RS12705 ENOG4105CKJ The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity) FHJ82_RS12710 ENOG4105KA4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity) FHJ82_RS12725 ENOG4106678 morphogenetic protein associated with SpoVID FHJ82_RS12730 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) FHJ82_RS12735 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase FHJ82_RS12740 ENOG4108IYU L-aspartate oxidase FHJ82_RS12755 ENOG4105CQC Prephenate dehydratase FHJ82_RS12765 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control FHJ82_RS12775 ENOG4105K46 50S ribosomal protein l27 FHJ82_RS12780 ENOG4105X36 (ribosomal) protein FHJ82_RS12785 ENOG4105KK9 This protein binds to 23S rRNA in the presence of protein L20 (By similarity) FHJ82_RS12800 ENOG4107QMS site-determining protein FHJ82_RS12805 ENOG4107YDG Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity) FHJ82_RS12810 ENOG4105YHC Rod shape-determining protein MreD FHJ82_RS12825 ENOG4105W5Q DNA repair protein (RadC FHJ82_RS12830 ENOG4108Z03 MAF-like protein FHJ82_RS12840 ENOG4106A3R peptidase FHJ82_RS12845 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase FHJ82_RS12850 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) FHJ82_RS12860 ENOG4106AR7 Spore coat protein FHJ82_RS12865 ENOG41068KH stage VI sporulation protein D FHJ82_RS12870 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase FHJ82_RS12875 ENOG4105D52 delta-aminolevulinic acid dehydratase FHJ82_RS12885 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) FHJ82_RS12895 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) FHJ82_RS12905 ENOG4105WHM Necessary for normal cell division and for the maintenance of normal septation (By similarity) FHJ82_RS12910 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) FHJ82_RS12915 ENOG4108IUQ atp-dependent protease FHJ82_RS12920 ENOG4105CHN ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity) FHJ82_RS12925 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation FHJ82_RS12935 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) FHJ82_RS12940 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) FHJ82_RS12945 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) FHJ82_RS12955 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase FHJ82_RS12960 ENOG4108ZP8 Acetolactate synthase small subunit FHJ82_RS12965 ENOG4105C7K acetolactate synthase FHJ82_RS12990 ENOG4105M59 Phosphodiesterase, mj0936 family FHJ82_RS12995 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) FHJ82_RS13000 ENOG4105ED0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity) FHJ82_RS13005 ENOG4108XJQ germination protein FHJ82_RS13010 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) FHJ82_RS13015 ENOG41067TZ transcriptional regulator, MarR family FHJ82_RS13020 ENOG4105PFC Transcriptional regulator FHJ82_RS13030 ENOG4105E33 succinate dehydrogenase FHJ82_RS13040 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit FHJ82_RS13050 ENOG4105CFH Aspartokinase FHJ82_RS13055 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) FHJ82_RS13060 ENOG4105K63 Thioredoxin FHJ82_RS13065 ENOG4105CZZ Alpha-N-arabinofuranosidase (EC 3.2.1.55) FHJ82_RS13070 ENOG4105C10 Electron transfer flavoprotein FHJ82_RS13075 ENOG4105BZJ Electron transfer flavoprotein FHJ82_RS13080 ENOG41060WC Enoyl-CoA hydratase FHJ82_RS13085 ENOG4107Z3H Transcriptional regulator, TetR family FHJ82_RS13090 ENOG4105CEY Amp-dependent synthetase and ligase FHJ82_RS13105 ENOG4105C98 muts2 protein FHJ82_RS13110 ENOG4105DCG PHP domain protein FHJ82_RS13125 ENOG4107FSS Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) FHJ82_RS13135 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) FHJ82_RS13140 ENOG4108RWN rrna methyltransferase FHJ82_RS13145 ENOG41067MF small acid-soluble spore protein FHJ82_RS13155 ENOG4105CQB FAD linked oxidase domain protein FHJ82_RS13170 ENOG4105CZZ Alpha-N-arabinofuranosidase (EC 3.2.1.55) FHJ82_RS13175 ENOG4105DRS transport system, permease FHJ82_RS13190 ENOG4108MDK Dehydrogenase FHJ82_RS13200 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase FHJ82_RS13205 ENOG4105EF1 ribulokinase FHJ82_RS13215 ENOG4107PMW Arabinan endo-1,5-alpha-L-arabinosidase FHJ82_RS13220 ENOG4105CN9 Peptidase m42 family protein FHJ82_RS13230 ENOG410696E Membrane FHJ82_RS13235 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) FHJ82_RS13240 ENOG4105VJV 50s ribosomal protein L35 FHJ82_RS13245 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) FHJ82_RS13250 ENOG41067MG lrgb family FHJ82_RS13260 ENOG4105DY9 regulatoR FHJ82_RS13265 ENOG4108HRK Histidine kinase FHJ82_RS13275 ENOG4105C22 threonyL-tRNA synthetase FHJ82_RS13280 ENOG4108TDW sporulation protein YtxC FHJ82_RS13305 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) FHJ82_RS13310 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase FHJ82_RS13315 ENOG4105KVH Transcriptional regulator FHJ82_RS13320 ENOG4105F27 Major Facilitator FHJ82_RS13325 ENOG4105CV8 reductase FHJ82_RS13330 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) FHJ82_RS13340 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) FHJ82_RS13345 ENOG4105C2M dna polymerase I FHJ82_RS13350 ENOG4105BZU Histidine kinase FHJ82_RS13355 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FHJ82_RS13365 ENOG4108HMX isocitrate dehydrogenase (NADP) FHJ82_RS13370 ENOG4105BZN citrate synthase FHJ82_RS13385 ENOG4105G7B Protein of unknown function (DUF2992) FHJ82_RS13400 ENOG4108REF Sporulation integral membrane protein ytvi FHJ82_RS13405 ENOG4105FS0 cytoplasmic membrane protein FHJ82_RS13410 ENOG4105CA9 Pyruvate kinase FHJ82_RS13415 ENOG4105CTQ phosphohexokinase FHJ82_RS13420 ENOG4107QM9 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity) FHJ82_RS13425 ENOG4107QTG Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity) FHJ82_RS13430 ENOG4105C6K Malic enzyme FHJ82_RS13435 ENOG4105C0B DNA polymerase III (alpha subunit) FHJ82_RS13440 ENOG4105VV2 FHJ82_RS13450 ENOG4106EVM FHJ82_RS13495 ENOG4105EPU Molybdenum cofactor synthesis domain protein FHJ82_RS13510 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) FHJ82_RS13515 ENOG4105KBJ sporulation protein ytfj FHJ82_RS13525 ENOG4105VK3 rdd domain containing protein FHJ82_RS13530 ENOG4105D07 Signal peptide peptidase, SppA FHJ82_RS13535 ENOG4108KKH Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) FHJ82_RS13540 ENOG4105EFZ amidohydrolase FHJ82_RS13545 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) FHJ82_RS13555 ENOG4105D8I Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity) FHJ82_RS13590 ENOG4105BZU Histidine kinase FHJ82_RS13600 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) FHJ82_RS13605 ENOG4105C26 Dehydrogenase FHJ82_RS13655 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) FHJ82_RS13670 ENOG4108Z0Z intracellular protease Pfpi family FHJ82_RS13690 ENOG4108NGU Transcriptional regulator FHJ82_RS13705 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) FHJ82_RS13715 ENOG4105F1V Acetoin utilization protein FHJ82_RS13720 ENOG4105W87 Cbs domain FHJ82_RS13725 ENOG4105DGU Histone deacetylase FHJ82_RS13730 ENOG4105ER2 Ompa motb domain protein FHJ82_RS13735 ENOG4107R0U MotA TolQ exbB proton channel FHJ82_RS13740 ENOG4105ETE Transcriptional regulator (LacI family FHJ82_RS13745 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase FHJ82_RS13765 ENOG4105DFU Cell wall formation (By similarity) FHJ82_RS13775 ENOG4108VDD TRNA binding domain protein FHJ82_RS13790 ENOG4108V0E nucleoside 2-deoxyribosyltransferase YtoQ FHJ82_RS13805 ENOG4105C6K Malic enzyme FHJ82_RS13810 ENOG4105C8F Beta-lactamase domain protein FHJ82_RS13815 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) FHJ82_RS13825 ENOG4108V15 phosphotransferase enzyme family FHJ82_RS13840 ENOG4107F58 2'-5' rna ligase FHJ82_RS13845 ENOG4105C6T cysteine synthase FHJ82_RS13850 ENOG4107QSE Dipeptidase FHJ82_RS13855 ENOG4105C7N Xanthine uracil vitamin C permease FHJ82_RS13870 ENOG4105YW5 deoR family transcriptional regulator FHJ82_RS13885 ENOG4105CBX hi0933 family FHJ82_RS13890 ENOG4105C94 Transporter FHJ82_RS13930 ENOG41085GJ domain protein FHJ82_RS13935 ENOG4105C8T Leucyl-tRNA synthetase FHJ82_RS13945 ENOG4105BZU Histidine kinase FHJ82_RS13950 ENOG410605W Major Facilitator FHJ82_RS13965 ENOG4105C19 ABC transporter FHJ82_RS13970 ENOG4105EWM Histidine kinase FHJ82_RS13980 ENOG4107R34 abc transporter permease protein FHJ82_RS13985 ENOG4105C19 ABC transporter FHJ82_RS14005 ENOG4105DVE abc transporter atp-binding protein FHJ82_RS14010 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family FHJ82_RS14020 ENOG4105N5T Radical SAM Protein FHJ82_RS14035 ENOG4107VXM glycerophosphoryl diester phosphodiesterase FHJ82_RS14045 ENOG4105E8V Alpha Beta Hydrolase Fold protein FHJ82_RS14050 ENOG4108Z0R Transferase FHJ82_RS14055 ENOG4105C85 amino acid FHJ82_RS14060 ENOG4105CAQ asparagine synthetase FHJ82_RS14065 ENOG4105CPH Catalyzes the formation of S-adenosylmethionine from methionine and ATP FHJ82_RS14070 ENOG4105DJ1 Phosphoenolpyruvate Carboxylase FHJ82_RS14085 ENOG4105D2X ABC transporter substrate-binding protein FHJ82_RS14095 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component FHJ82_RS14110 ENOG4108RMU ferritin dps family protein FHJ82_RS14125 ENOG4106762 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity) FHJ82_RS14130 ENOG4105VAS Could be involved in insertion of integral membrane proteins into the membrane (By similarity) FHJ82_RS14135 ENOG4108V2W Carbonate dehydratase FHJ82_RS14140 ENOG4105NRA 50s ribosomal protein l31 type b FHJ82_RS14165 ENOG4105DTQ mandelate racemase muconate lactonizing FHJ82_RS14170 ENOG4105CEY Amp-dependent synthetase and ligase FHJ82_RS14175 ENOG4108IPT Naphthoate synthase FHJ82_RS14180 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) FHJ82_RS14185 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) FHJ82_RS14190 ENOG4105E4F Isochorismate synthase FHJ82_RS14325 ENOG4105N67 Proton-coupled thiamine transporter YuaJ FHJ82_RS14330 ENOG4105DZ6 Band 7 protein FHJ82_RS14340 ENOG4106DF1 FHJ82_RS14345 ENOG4108VNY MOSC domain protein FHJ82_RS14350 ENOG4108JB8 alcohol dehydrogenase FHJ82_RS14360 ENOG4105TRT Transcriptional regulator FHJ82_RS14375 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj FHJ82_RS14380 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) FHJ82_RS14400 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) FHJ82_RS14410 ENOG4105EE0 oxidoreductase FHJ82_RS14415 ENOG4108Z0Z intracellular protease Pfpi family FHJ82_RS14420 ENOG4105C8Q Methyl-accepting chemotaxis FHJ82_RS14425 ENOG4105C8Q Methyl-accepting chemotaxis FHJ82_RS14430 ENOG4105C8Q Methyl-accepting chemotaxis FHJ82_RS14435 ENOG4105C8Q Methyl-accepting chemotaxis FHJ82_RS14450 ENOG4105EA8 2-Nitropropane dioxygenase FHJ82_RS14455 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme FHJ82_RS14465 ENOG4105C37 (CBS) domain FHJ82_RS14480 ENOG4107PBV potassium channel FHJ82_RS14485 ENOG4107PBV potassium channel FHJ82_RS14500 ENOG4107QYV phosphohexose isomerase FHJ82_RS14510 ENOG4105CHJ isochorismatase hydrolase FHJ82_RS14520 ENOG4107QW4 alcohol dehydrogenase FHJ82_RS14525 ENOG4105WG9 Conserved Protein FHJ82_RS14535 ENOG4105CHM Aminotransferase FHJ82_RS14540 ENOG4108ZB6 transcriptional regulator AsnC family FHJ82_RS14545 ENOG4108MUZ hydrolase FHJ82_RS14555 ENOG4105C87 Aminotransferase class I and II FHJ82_RS14560 ENOG4108HGU Histidine kinase FHJ82_RS14565 ENOG4105Y38 Kinase-associated protein B FHJ82_RS14580 ENOG4105BZ4 penicillin-binding protein FHJ82_RS14585 ENOG4105KIR Thiol-disulfide oxidoreductase dcc FHJ82_RS14600 ENOG4108MRH transcriptional regulatory protein FHJ82_RS14605 ENOG4105DIH basic membrane FHJ82_RS14610 ENOG4108JQ9 ABC transporter FHJ82_RS14615 ENOG4105UIB (ABC) transporter FHJ82_RS14630 ENOG4105D65 subunit l FHJ82_RS14635 ENOG4105HC0 Na H antiporter FHJ82_RS14640 ENOG4108ZE9 Monovalent cation H antiporter subunit C FHJ82_RS14645 ENOG4108JPZ Monovalent cation H antiporter subunit D FHJ82_RS14650 ENOG4105SC1 monovalent cation H antiporter subunit E FHJ82_RS14660 ENOG4105KJM monovalent cation h antiporter subunit g FHJ82_RS14665 ENOG4105KA0 thioesterase Superfamily protein FHJ82_RS14675 ENOG4105BZU Histidine kinase FHJ82_RS14705 ENOG4105D58 Diguanylate phosphodiesterase FHJ82_RS14710 ENOG4105DAP Nicotinate phosphoribosyltransferase FHJ82_RS14735 ENOG4105C02 permease FHJ82_RS14750 ENOG410904N short-chain dehydrogenase reductase FHJ82_RS14785 ENOG4108K8K Transcriptional regulator FHJ82_RS14790 ENOG4105DCF alanine dehydrogenase FHJ82_RS14800 ENOG4105WQT MbtH domain protein FHJ82_RS14805 ENOG4105CEY Amp-dependent synthetase and ligase FHJ82_RS14810 ENOG4105WQI isochorismatase FHJ82_RS14815 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase FHJ82_RS14820 ENOG4105E4F Isochorismate synthase FHJ82_RS14825 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase FHJ82_RS14830 ENOG4105NIV Esterase FHJ82_RS14850 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) FHJ82_RS14860 ENOG41069ER domain protein FHJ82_RS14875 ENOG4105CEP NADH dehydrogenase FHJ82_RS14890 ENOG4107SJ1 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity) FHJ82_RS14905 ENOG4105CJ1 ABC, transporter FHJ82_RS14925 ENOG4105D9U N-acetyltransferase FHJ82_RS14930 ENOG4108VHC Short-chain dehydrogenase reductase Sdr FHJ82_RS14935 ENOG4108YX9 iron--sulfur cluster insertion protein erpA FHJ82_RS14940 ENOG4105E4Z Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity) FHJ82_RS14950 ENOG4105ZKE UPF0349 protein FHJ82_RS14965 ENOG41083MR nifu domain-containing protein FHJ82_RS14970 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein FHJ82_RS14975 ENOG4105D5I Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity) FHJ82_RS14980 ENOG4108IYI Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity) FHJ82_RS14985 ENOG4105D6E homoserine dehydrogenase FHJ82_RS14995 ENOG4108W5N phosphatidylglycerophosphatase a FHJ82_RS15000 ENOG4105D4U had-superfamily hydrolase, subfamily iia FHJ82_RS15010 ENOG4105MMD transcriptional regulator FHJ82_RS15015 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) FHJ82_RS15020 ENOG4105FAA peptidase M23 FHJ82_RS15025 ENOG4108YTE sporulation protein YunB FHJ82_RS15030 ENOG4107R8B 5'-nucleotidase FHJ82_RS15050 ENOG4105CD3 dihydroorotase FHJ82_RS15055 ENOG4105G9B Transcriptional regulator FHJ82_RS15080 ENOG4105C5R Aminotransferase FHJ82_RS15090 ENOG4108K8S endonuclease I FHJ82_RS15095 ENOG4108IJ9 (ABC) transporter FHJ82_RS15100 ENOG4105FDP GntR family transcriptional regulator FHJ82_RS15105 ENOG4108KPW sugar kinase FHJ82_RS15110 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component FHJ82_RS15115 ENOG4105F0P binding-protein-dependent transport systems inner membrane Component FHJ82_RS15120 ENOG4105XN3 extracellular solute-binding protein family 1 FHJ82_RS15125 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine FHJ82_RS15130 ENOG4108Z6Z Transcriptional regulator FHJ82_RS15155 ENOG4105PKS Excinuclease abc c subunit domain protein FHJ82_RS15160 ENOG4107VFR oxidoreductase FHJ82_RS15180 ENOG41083Q9 chitosanase FHJ82_RS15185 ENOG4105DIW FeS assembly protein SUFB FHJ82_RS15190 ENOG4108UNV SUF system FeS assembly protein, NifU family FHJ82_RS15195 ENOG4105C9B Cysteine desulfurase FHJ82_RS15200 ENOG4105JRK feS assembly protein SufD FHJ82_RS15205 ENOG4105C3K feS assembly ATPase SufC FHJ82_RS15220 ENOG4105D01 (LipO)protein FHJ82_RS15225 ENOG4108UMI ABC transporter, permease FHJ82_RS15230 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) FHJ82_RS15255 ENOG4105KE9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity) FHJ82_RS15260 ENOG41080E8 Transcriptional regulator, Spx MgsR family FHJ82_RS15265 ENOG4105C1G acyl-Coa dehydrogenase FHJ82_RS15270 ENOG4105CHU acetyl-coa acetyltransferase FHJ82_RS15300 ENOG41067TZ transcriptional regulator, MarR family FHJ82_RS15305 ENOG4105C0R drug resistance transporter emrb qaca subfamily FHJ82_RS15310 ENOG4105MDS 4-oxalocrotonate tautomerase FHJ82_RS15320 ENOG4105EGI Transcriptional regulator FHJ82_RS15330 ENOG4105C5Q Transcriptional regulator FHJ82_RS15350 ENOG4105E0A ABC, transporter FHJ82_RS15365 ENOG4105E1F short-chain dehydrogenase reductase FHJ82_RS15370 ENOG4105HUF DNA protection during starvation protein FHJ82_RS15375 ENOG4105C0H protease FHJ82_RS15385 ENOG4105F3H Histidine kinase FHJ82_RS15395 ENOG41067SE Tetr family transcriptional regulator FHJ82_RS15400 ENOG4105C9Q fumarate hydratase class II FHJ82_RS15425 ENOG4105WH1 Two component transcriptional regulator luxr family FHJ82_RS15430 ENOG4105ENE Histidine kinase FHJ82_RS15445 ENOG41087YS Phage shock protein A FHJ82_RS15460 ENOG4108WBT adenosyltransferase FHJ82_RS15465 ENOG4105E0A ABC, transporter FHJ82_RS15480 ENOG4105EWI Short-chain dehydrogenase reductase Sdr FHJ82_RS15485 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein FHJ82_RS15495 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FHJ82_RS15505 ENOG4106DF4 Sigma-70, region 4 FHJ82_RS15515 ENOG4105F0F Oxalate decarboxylase FHJ82_RS15525 ENOG4105E0A ABC, transporter FHJ82_RS15530 ENOG4105EHG Permease protein FHJ82_RS15535 ENOG4105DQ5 transport system permease protein FHJ82_RS15545 ENOG4105D5Q Arginine ornithine antiporter FHJ82_RS15555 ENOG4107K5X Membrane-bound metal-dependent hydrolase FHJ82_RS15560 ENOG4107QZ2 Sulfatase FHJ82_RS15565 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family FHJ82_RS15570 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein FHJ82_RS15575 ENOG4105E0C molybdate abc transporter FHJ82_RS15580 ENOG4105WH1 Two component transcriptional regulator luxr family FHJ82_RS15585 ENOG4105BZU Histidine kinase FHJ82_RS15590 ENOG4105CJ1 ABC, transporter FHJ82_RS15600 ENOG4108KYE ABC-2 type transporter FHJ82_RS15615 ENOG4105EEQ Na H antiporter FHJ82_RS15620 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) FHJ82_RS15625 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) FHJ82_RS15630 ENOG4105EEM helicase FHJ82_RS15635 ENOG4105EN6 Membrane FHJ82_RS15650 ENOG4107ZQN disulfide bond FHJ82_RS15655 ENOG4105C59 p-type ATPase FHJ82_RS15660 ENOG4105C59 p-type ATPase FHJ82_RS15665 ENOG410681U heavy metal transport detoxification protein FHJ82_RS15670 ENOG4105VPX protein, conserved in bacteria FHJ82_RS15675 ENOG4105D9R oxidoreductase FHJ82_RS15680 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) FHJ82_RS15695 ENOG4105DEN Luciferase family FHJ82_RS15700 ENOG4105CDA abc transporter atp-binding protein FHJ82_RS15725 ENOG4108XSB acetyltransferase, (GNAT) family FHJ82_RS15730 ENOG4108KSA LysR family transcriptional regulator FHJ82_RS15735 ENOG4105EWI Short-chain dehydrogenase reductase Sdr FHJ82_RS15775 ENOG4108UH4 Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity) FHJ82_RS15780 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) FHJ82_RS15790 ENOG4105XZU Preprotein translocase, subunit SecG FHJ82_RS15810 ENOG4105KVH Transcriptional regulator FHJ82_RS15835 ENOG4105DA5 (ABC) transporter FHJ82_RS15840 ENOG4105R40 Glycine betaine carnitine choline FHJ82_RS15845 ENOG4108HQR Glycine betaine FHJ82_RS15850 ENOG4105E90 ABC transporter FHJ82_RS15855 ENOG4108IJ8 ABC transporter FHJ82_RS15860 ENOG4107HG4 Transcriptional regulator FHJ82_RS15865 ENOG4105R40 Glycine betaine carnitine choline FHJ82_RS15870 ENOG4108HQR Glycine betaine FHJ82_RS15875 ENOG4105E90 ABC transporter FHJ82_RS15880 ENOG4108IJ8 ABC transporter FHJ82_RS15885 ENOG4107HG4 Transcriptional regulator FHJ82_RS15890 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein FHJ82_RS15900 ENOG4105T65 Membrane-associated protein FHJ82_RS15905 ENOG4108W0I acetyltransferase FHJ82_RS15920 ENOG4105FJR Lmbe family FHJ82_RS15940 ENOG4108IAJ Nad-dependent epimerase dehydratase FHJ82_RS15945 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase FHJ82_RS15950 ENOG4107QQG Dehydrogenase FHJ82_RS15955 ENOG4105IIU Aminopeptidase FHJ82_RS15960 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) FHJ82_RS15965 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) FHJ82_RS15970 ENOG4105CP7 Triose-phosphate isomerase FHJ82_RS15975 ENOG4105BZA Phosphoglycerate kinase FHJ82_RS15980 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase FHJ82_RS15995 ENOG4105CMD Transcriptional regulator, GntR family FHJ82_RS16000 ENOG4105DEN Luciferase family FHJ82_RS16010 ENOG4105GZI Transcriptional regulator FHJ82_RS16015 ENOG4107RT3 EamA-like transporter family FHJ82_RS16035 ENOG410667J hydrolase FHJ82_RS16040 ENOG4106KNT transcriptional regulator FHJ82_RS16045 ENOG4105CMG Carbohydrate kinase FHJ82_RS16050 ENOG4105C6Z Gluconate FHJ82_RS16075 ENOG4107QR9 Iron-sulfur cluster binding protein FHJ82_RS16080 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) FHJ82_RS16085 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FHJ82_RS16090 ENOG4105JXH GntR family transcriptional regulator FHJ82_RS16095 ENOG4105DAA L-lactate FHJ82_RS16100 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FHJ82_RS16110 ENOG4108ZPC Polysaccharide pyruvyl transferase FHJ82_RS16115 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase FHJ82_RS16120 ENOG4105MME Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family FHJ82_RS16125 ENOG4105D3Q Sugar transferase FHJ82_RS16135 ENOG4105K64 Glycosyl transferase, family 2 FHJ82_RS16145 ENOG4107QRS glycosyltransferase group 2 family protein FHJ82_RS16150 ENOG41068W6 Capsular polysaccharide biosynthesis protein FHJ82_RS16155 ENOG4108KMV Glycosyl transferase (Group 1 FHJ82_RS16160 ENOG4105K64 Glycosyl transferase, family 2 FHJ82_RS16165 ENOG4108PQP glycosyl transferase group 1 FHJ82_RS16175 ENOG4108QV3 biosynthesis protein FHJ82_RS16180 ENOG4105HTX biosynthesis protein FHJ82_RS16190 ENOG4105EBR Carboxylesterase FHJ82_RS16195 ENOG4105NAE bifunctional deaminase-reductase domain protein FHJ82_RS16205 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 FHJ82_RS16210 ENOG4105PY6 Phenolic acid decarboxylase FHJ82_RS16255 ENOG4108HKT sucrose-6-phosphate hydrolase FHJ82_RS16260 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) FHJ82_RS16265 ENOG4105ETE Transcriptional regulator (LacI family FHJ82_RS16270 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) FHJ82_RS16275 ENOG4107URF beta-phospho-glucomutase FHJ82_RS16280 ENOG4105CG3 alpha amylase, catalytic region FHJ82_RS16295 ENOG4105EG2 ABC transporter, permease FHJ82_RS16300 ENOG4105D56 permease protein FHJ82_RS16305 ENOG4107FKK extracellular solute-binding protein family 1 FHJ82_RS16310 ENOG4108IUK alpha amylase, catalytic FHJ82_RS16315 ENOG4105FKQ transcriptional regulator FHJ82_RS16320 ENOG4108URH decarboxylase FHJ82_RS16325 ENOG4105TPC MazG nucleotide pyrophosphohydrolase domain FHJ82_RS16330 ENOG4105CHH sulfate transporter FHJ82_RS16335 ENOG4108V2W Carbonate dehydratase FHJ82_RS16345 ENOG4105C5I Dehydrogenase FHJ82_RS16350 ENOG4105GGE ribonuclease FHJ82_RS16355 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase FHJ82_RS16360 ENOG4105KRI phosphocarrier protein (HPr FHJ82_RS16365 ENOG4105CIE May be required for sporulation (By similarity) FHJ82_RS16370 ENOG4105CHW UPF0052 protein FHJ82_RS16375 ENOG4105C21 Displays ATPase and GTPase activities (By similarity) FHJ82_RS16380 ENOG4108Z4K mutator MutT protein FHJ82_RS16385 ENOG4105C3M thioredoxin reductase FHJ82_RS16400 ENOG4105BZU Histidine kinase FHJ82_RS16405 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FHJ82_RS16410 ENOG4105BZ1 (ABC) transporter FHJ82_RS16415 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase FHJ82_RS16420 ENOG4105C0S IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) FHJ82_RS16425 ENOG4105CJV Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase FHJ82_RS16430 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) FHJ82_RS16435 ENOG4105ECC imidazole-glycerol-phosphate dehydratase FHJ82_RS16440 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) FHJ82_RS16445 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) FHJ82_RS16450 ENOG4108IQ6 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity) FHJ82_RS16460 ENOG4108S4C acetyltransferase FHJ82_RS16465 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) FHJ82_RS16475 ENOG4105D1C Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity) FHJ82_RS16480 ENOG4105CE4 GlcNAc 6-P deacetylase FHJ82_RS16485 ENOG4105CKA Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity) FHJ82_RS16495 ENOG4105J7D transcriptional regulator FHJ82_RS16500 ENOG41088CQ domain protein FHJ82_RS16505 ENOG41086DT Membrane protein of unknown function FHJ82_RS16510 ENOG41067S9 phage shock protein C, PspC FHJ82_RS16515 ENOG4108PY7 FHJ82_RS16530 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) FHJ82_RS16535 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) FHJ82_RS16550 ENOG4105MKU Transcriptional regulator FHJ82_RS16580 ENOG4105CN1 protease FHJ82_RS16585 ENOG4108M26 parallel beta-helix repeat protein FHJ82_RS16590 ENOG4105CRP Part of the ABC transporter FtsEX involved in FHJ82_RS16595 ENOG4105CAK Cell division ATP-binding protein ftsE FHJ82_RS16615 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving FHJ82_RS16620 ENOG4105MS2 ribosomal subunit Interface protein FHJ82_RS16635 ENOG4105MQ3 flagellar protein FliS FHJ82_RS16645 ENOG4105I03 Flagellin FHJ82_RS16650 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) FHJ82_RS16655 ENOG4105W5T Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity) FHJ82_RS16665 ENOG4105DTJ flagellar hook-associated protein FHJ82_RS16670 ENOG4105E1Q flagellar hook-associated protein FHJ82_RS16685 ENOG4105RU3 FHJ82_RS16690 ENOG41081UC Inherit from COG: Competence protein FHJ82_RS16710 ENOG4105WH1 Two component transcriptional regulator luxr family FHJ82_RS16715 ENOG4105BZU Histidine kinase FHJ82_RS16720 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein FHJ82_RS16725 ENOG4108KGH TRANSCRIPTIONal FHJ82_RS16730 ENOG4105ESV Glycosyl transferase, family 4 FHJ82_RS16735 ENOG4107EF8 Glycosyl transferase (Group 1 FHJ82_RS16750 ENOG4105QZI O-Antigen Polymerase FHJ82_RS16755 ENOG4105C6Y Udp-glucose 6-dehydrogenase FHJ82_RS16760 ENOG4107RA4 Glycosyl transferase (Group 1 FHJ82_RS16765 ENOG4105PSV Polysaccharide Biosynthesis Protein FHJ82_RS16770 ENOG4105D3Q Sugar transferase FHJ82_RS16775 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase FHJ82_RS16780 ENOG4105JFG SpoIID LytB domain protein FHJ82_RS16795 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase FHJ82_RS16800 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase FHJ82_RS16805 ENOG4105EY8 ABC transporter FHJ82_RS16815 ENOG4107SJB teichoic acid biosynthesis FHJ82_RS16825 ENOG4107ZIC Glycerol-3-phosphate cytidylyltransferase FHJ82_RS16835 ENOG4107RZX Teichoic acid biosynthesis protein FHJ82_RS16845 ENOG4105DG6 mannose-6-phosphate isomerase FHJ82_RS16860 ENOG4108NHD germination protein FHJ82_RS16865 ENOG4107R8N Glycosyl transferase, family 2 FHJ82_RS16870 ENOG4105C54 Major Facilitator superfamily FHJ82_RS16875 ENOG4108KGH TRANSCRIPTIONal FHJ82_RS16880 ENOG4105J7I hydrolase FHJ82_RS16885 ENOG4106UBQ FHJ82_RS16890 ENOG4105K4H Nlp p60 protein FHJ82_RS16900 ENOG4105PNM synthesis protein FHJ82_RS16910 ENOG4105N98 Capsule biosynthesis protein capB FHJ82_RS16915 ENOG4105E1K spore germination protein FHJ82_RS16930 ENOG4105ETE Transcriptional regulator (LacI family FHJ82_RS16935 ENOG4108RVA ribokinase FHJ82_RS16940 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) FHJ82_RS16945 ENOG4105C2J ABC transporter FHJ82_RS16950 ENOG4105CNN ABC, transporter FHJ82_RS16955 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator FHJ82_RS16965 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein FHJ82_RS16970 ENOG4107FQX Alpha-acetolactate decarboxylase FHJ82_RS16980 ENOG4107RSM transcriptional regulator FHJ82_RS16995 ENOG4106UIA FHJ82_RS17010 ENOG4107XC4 flavin reductase domain protein, FMN-binding FHJ82_RS17020 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) FHJ82_RS17030 ENOG4105CAH Chromate FHJ82_RS17035 ENOG4105FGV Chromate FHJ82_RS17045 ENOG4108WS4 fmn reductase FHJ82_RS17050 ENOG4107V2S Transcriptional regulator FHJ82_RS17055 ENOG4105Y7X Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity) FHJ82_RS17095 ENOG4108XI2 Domain of unknown function (DUF1963) FHJ82_RS17100 ENOG4105C6Y Udp-glucose 6-dehydrogenase FHJ82_RS17105 ENOG4108RB3 Capsular polysaccharide biosynthesis protein FHJ82_RS17110 ENOG4107YJ4 chain length determinant protein FHJ82_RS17115 ENOG4105HTX biosynthesis protein FHJ82_RS17125 ENOG4105KBK Zinc finger, swim domain protein FHJ82_RS17130 ENOG4105C0D helicase FHJ82_RS17135 ENOG410667J hydrolase FHJ82_RS17140 ENOG4105E98 transcriptional regulator DeoR family FHJ82_RS17145 ENOG4105Z8H single-stranded DNA-binding protein FHJ82_RS17160 ENOG4105M2E Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity) FHJ82_RS17165 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) FHJ82_RS17175 ENOG4105CGA flagellar basal-body rod protein FlgG FHJ82_RS17185 ENOG4105DFF Rod shape-determining protein mreb FHJ82_RS17190 ENOG4105MT0 Sporulation transcriptional regulator spoiiid FHJ82_RS17195 ENOG4107MII Sugar-specific transcriptional regulator TrmB FHJ82_RS17200 ENOG4105CZM Major Facilitator FHJ82_RS17205 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease FHJ82_RS17210 ENOG41080V3 Major Facilitator superfamily FHJ82_RS17215 ENOG4105D3W isochorismatase FHJ82_RS17220 ENOG4105BZU Histidine kinase FHJ82_RS17230 ENOG4105CNI cell division protein FtsW FHJ82_RS17235 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase FHJ82_RS17245 ENOG4105FRN stage II sporulation protein FHJ82_RS17250 ENOG4107TCE N-acetyltransferase FHJ82_RS17265 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) FHJ82_RS17270 ENOG4106BRK FHJ82_RS17275 ENOG4107T94 Endo-14-beta-xylanase FHJ82_RS17285 ENOG4108Z40 Transcriptional regulator FHJ82_RS17290 ENOG4105CQM Urea amidohydrolase subunit alpha FHJ82_RS17295 ENOG4105KI2 Urea amidohydrolase subunit beta FHJ82_RS17300 ENOG4108YZ9 Urea amidohydrolase subunit gamma FHJ82_RS17320 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) FHJ82_RS17325 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) FHJ82_RS17335 ENOG4108TF4 von Willebrand factor, type A FHJ82_RS17350 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) FHJ82_RS17360 ENOG4106778 Protein of unknown function (DUF1146) FHJ82_RS17370 ENOG4105KNM Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) FHJ82_RS17375 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) FHJ82_RS17380 ENOG4105J80 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity) FHJ82_RS17385 ENOG4105CDG Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity) FHJ82_RS17390 ENOG4107YZM F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) FHJ82_RS17405 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) FHJ82_RS17415 ENOG4105CZ5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity) FHJ82_RS17420 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) FHJ82_RS17425 ENOG4108UIC UPF0340 protein FHJ82_RS17430 ENOG4108YZG isomerase FHJ82_RS17435 ENOG4107WAU Protein tyrosine phosphatase FHJ82_RS17440 ENOG410815N Probably functions as a manganese efflux pump (By similarity) FHJ82_RS17445 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) FHJ82_RS17475 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) FHJ82_RS17480 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase FHJ82_RS17490 ENOG4107TT2 Auxin Efflux Carrier FHJ82_RS17495 ENOG4105C6K Malic enzyme FHJ82_RS17500 ENOG4107104 thymidine kinase FHJ82_RS17510 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) FHJ82_RS17515 ENOG4105CBT Fructose-1,6-bisphosphatase FHJ82_RS17520 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) FHJ82_RS17530 ENOG4105D2N Aldolase FHJ82_RS17535 ENOG410812K response regulator receiver protein FHJ82_RS17545 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) FHJ82_RS17555 ENOG4105DF6 Fe-S oxidoreductase FHJ82_RS17565 ENOG4105E5J UV damage endonuclease FHJ82_RS17575 ENOG4105BZ1 (ABC) transporter FHJ82_RS17580 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) FHJ82_RS17595 ENOG4105R3A Nitrate reductase FHJ82_RS17600 ENOG4108IUE nitrate reductase beta subunit FHJ82_RS17620 ENOG4107V6Q Cyclic nucleotide-binding domain FHJ82_RS17630 ENOG4105C75 arginyL-tRNA synthetase FHJ82_RS17635 ENOG410684U Domain of unknown function (DUF1934) FHJ82_RS17655 ENOG4107JM4 Tetratricopeptide repeat FHJ82_RS17665 ENOG4105CYW agmatinase FHJ82_RS17675 ENOG4105BZ4 penicillin-binding protein FHJ82_RS17685 ENOG4108XFG YwhD family FHJ82_RS17690 ENOG4108Z4T Peptidase M50 FHJ82_RS17695 ENOG41069HH 4-oxalocrotonate tautomerase FHJ82_RS17700 ENOG41067TZ transcriptional regulator, MarR family FHJ82_RS17705 ENOG4105CUB amino acid FHJ82_RS17715 ENOG4105DCI Phosphohydrolase FHJ82_RS17725 ENOG4108VCI transcription factor, rsfa family FHJ82_RS17730 ENOG4105K7K Transcriptional regulator FHJ82_RS17740 ENOG4105CJ1 ABC, transporter FHJ82_RS17745 ENOG4108TU7 Inherit from COG: (ABC) transporter FHJ82_RS17770 ENOG4105JGI Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity) FHJ82_RS17775 ENOG4105DUM transcriptional regulator, lysR family FHJ82_RS17780 ENOG4105HMI Membrane FHJ82_RS17785 ENOG4108IJ2 phosphate acetyltransferase FHJ82_RS17790 ENOG4107JTW chlorite dismutase FHJ82_RS17800 ENOG4105CHM Aminotransferase FHJ82_RS17830 ENOG4105FCW Major Facilitator superfamily FHJ82_RS17835 ENOG4105C2C drug resistance transporter, Bcr CflA FHJ82_RS17850 ENOG4105C26 Dehydrogenase FHJ82_RS17855 ENOG4105D82 Glutamate dehydrogenase FHJ82_RS17865 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FHJ82_RS17885 ENOG4107ZIM Dtdp-4-dehydrorhamnose 3,5-epimerase FHJ82_RS17890 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase FHJ82_RS17895 ENOG4105C1B dTDP-glucose 4-6-dehydratase FHJ82_RS17900 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) FHJ82_RS17905 ENOG4107P9E Inherit from COG: pseudaminic acid biosynthesis-associated protein PseG FHJ82_RS17910 ENOG4107TY6 Acylneuraminate cytidylyltransferase FHJ82_RS17920 ENOG41067MN Spore coat polysaccharide biosynthesis protein spsD FHJ82_RS17925 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase FHJ82_RS17960 ENOG4105D5S Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity) FHJ82_RS17965 ENOG4108RJ9 Glycosyl transferase, family 2 FHJ82_RS17985 ENOG4105DWF phosphomethylpyrimidine kinase FHJ82_RS18000 ENOG4105C5Y PTS System FHJ82_RS18015 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin FHJ82_RS18020 ENOG4105DEN Luciferase family FHJ82_RS18025 ENOG4108DBC nitroreductase FHJ82_RS18035 ENOG4105I4A GCN5-related N-acetyltransferase FHJ82_RS18055 ENOG4105BZ9 Cytochrome C oxidase, subunit I FHJ82_RS18060 ENOG4105E2S oxidase) subunit II FHJ82_RS18065 ENOG4107BMA Transglycosylase associated protein FHJ82_RS18075 ENOG4105CRD Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity) FHJ82_RS18080 ENOG4105WH5 Teichoic acid glycosylation protein FHJ82_RS18105 ENOG4107ZXU DSBA oxidoreductase FHJ82_RS18110 ENOG4105DBE peroxidase FHJ82_RS18115 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) FHJ82_RS18120 ENOG4105C4U 4-methyl-5-beta-hydroxyethylthiazole kinase FHJ82_RS18125 ENOG4105CMU LysR family (Transcriptional regulator FHJ82_RS18130 ENOG4105VAW lrga family FHJ82_RS18135 ENOG41067MG lrgb family FHJ82_RS18145 ENOG4107TXC Transcriptional regulator FHJ82_RS18155 ENOG4105DR4 Methyltransferase FHJ82_RS18165 ENOG4105CK1 PTS System FHJ82_RS18170 ENOG4105J8Z peptidase S8 and S53, subtilisin, kexin, sedolisin FHJ82_RS18175 ENOG4105X1N Glycosyl transferase family 8 FHJ82_RS18185 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase FHJ82_RS18195 ENOG4108IQD Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity) FHJ82_RS18200 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein FHJ82_RS18205 ENOG4105X96 Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA (By similarity) FHJ82_RS18210 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD FHJ82_RS18215 ENOG4105CM2 brancheD-chain amino acid aminotransferase FHJ82_RS18220 ENOG4105F8D glycoside hydrolase family 4 FHJ82_RS18225 ENOG4105VCP PTS System FHJ82_RS18230 ENOG4105CK1 PTS System FHJ82_RS18235 ENOG4105VZJ PTS System FHJ82_RS18240 ENOG4105EMD TRANSCRIPTIONal FHJ82_RS18250 ENOG4105DQ5 transport system permease protein FHJ82_RS18255 ENOG4105EHG Permease protein FHJ82_RS18265 ENOG41082YX Transcriptional regulator, arsr family FHJ82_RS18270 ENOG4107R5R arsenical pump membrane protein FHJ82_RS18275 ENOG4105VZJ PTS System FHJ82_RS18280 ENOG4105VCP PTS System FHJ82_RS18285 ENOG4105CK1 PTS System FHJ82_RS18290 ENOG4105CS2 ec 3.2.1.21 FHJ82_RS18300 ENOG4105DG6 mannose-6-phosphate isomerase FHJ82_RS18310 ENOG4105CH6 catalase FHJ82_RS18315 ENOG4107QHE Choloylglycine hydrolase FHJ82_RS18320 ENOG4105ETS cytosine purines uracil thiamine allantoin FHJ82_RS18345 ENOG4108NEV two component transcriptional regulator, LytTR family FHJ82_RS18365 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) FHJ82_RS18370 ENOG4108JJ8 (ABC) transporter FHJ82_RS18375 ENOG4108JJ9 ABC, transporter FHJ82_RS18380 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FHJ82_RS18385 ENOG4105C4M (Ubiquinol oxidase) subunit I FHJ82_RS18390 ENOG4105D2K citrate carrier protein FHJ82_RS18395 ENOG4107BJW polysaccharide deacetylase FHJ82_RS18410 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) FHJ82_RS18420 ENOG4105CMR udp-glucose 4-epimerase FHJ82_RS18425 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) FHJ82_RS18445 ENOG4105DHI Methyltransferase FHJ82_RS18465 ENOG4105CH6 catalase FHJ82_RS18470 ENOG4105D4T Citrate transporter FHJ82_RS18485 ENOG4105DEU major facilitator superfamily FHJ82_RS18490 ENOG4105C1J atp-dependent rna helicase FHJ82_RS18495 ENOG4108NR7 pectate lyase FHJ82_RS18505 ENOG4107YZX Universal stress protein FHJ82_RS18575 ENOG4105C84 Histidine ammonia-lyase FHJ82_RS18580 ENOG4105CGP Urocanate hydratase FHJ82_RS18585 ENOG4105CI2 imidazolone-5-propionate hydrolase FHJ82_RS18590 ENOG4107W25 arginase agmatinase formiminoglutamase FHJ82_RS18600 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) FHJ82_RS18605 ENOG4105D9N nucleoside FHJ82_RS18610 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) FHJ82_RS18615 ENOG4107RHR regulatoR FHJ82_RS18620 ENOG410667J hydrolase FHJ82_RS18650 ENOG4108V5C ABC transporter FHJ82_RS18685 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FHJ82_RS18710 ENOG4105WZ4 isomerase FHJ82_RS18715 ENOG4105F0H myo-inositol catabolism protein FHJ82_RS18720 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) FHJ82_RS18730 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) FHJ82_RS18740 ENOG4105EDK PfkB domain protein FHJ82_RS18750 ENOG4105C26 Dehydrogenase FHJ82_RS18760 ENOG4105CPC Aldo Keto reductase FHJ82_RS18765 ENOG4107QNK )-transporter FHJ82_RS18770 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) FHJ82_RS18780 ENOG41061TZ Short-chain dehydrogenase reductase Sdr FHJ82_RS18785 ENOG4108S01 response regulator FHJ82_RS18790 ENOG4108ZGX Histidine kinase FHJ82_RS18795 ENOG4105ECK Fatty Acid Desaturase FHJ82_RS18800 ENOG4105ST3 Transcriptional regulator FHJ82_RS18805 ENOG4105C26 Dehydrogenase FHJ82_RS18810 ENOG4108ITS PQQ enzyme repeat FHJ82_RS18820 ENOG4105WAB arsR family transcriptional regulator FHJ82_RS18825 ENOG4105F27 Major Facilitator FHJ82_RS18830 ENOG41085PJ rdd domain containing protein FHJ82_RS18840 ENOG4105D3R alkyl hydroperoxide reductase FHJ82_RS18845 ENOG4108JU3 Alkyl hydroperoxide reductase FHJ82_RS18850 ENOG4107R3N Filamentation induced by cAMP protein fic FHJ82_RS18855 ENOG4105C85 amino acid FHJ82_RS18860 ENOG4105DMC D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3 FHJ82_RS18865 ENOG4108XHQ (2Fe-2S)-binding domain protein FHJ82_RS18885 ENOG4105XRQ Xanthine dehydrogenase accessory factor FHJ82_RS18920 ENOG4108UXA Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity) FHJ82_RS18940 ENOG4105NUN Orthopoxvirus protein of unknown function (DUF830) FHJ82_RS18945 ENOG4105CPC Aldo Keto reductase FHJ82_RS18950 ENOG4105WQG acetyltransferase FHJ82_RS18960 ENOG41066UZ arginase EC 3.5.3.1 FHJ82_RS18965 ENOG4108IQI permease FHJ82_RS18970 ENOG4105C8Y Acetylornithine aminotransferase FHJ82_RS18980 ENOG41082BM Transcriptional regulator, arsr family FHJ82_RS18985 ENOG4108JUB Transcriptional regulator FHJ82_RS18995 ENOG4105C5H ABC transporter FHJ82_RS19010 ENOG4105D06 uba thif-type nad fad binding protein FHJ82_RS19015 ENOG41062D9 Histidine kinase FHJ82_RS19020 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FHJ82_RS19025 ENOG4105C0H protease FHJ82_RS19030 ENOG4105Q2H domain protein FHJ82_RS19045 ENOG4105BZU Histidine kinase FHJ82_RS19050 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FHJ82_RS19075 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis FHJ82_RS19080 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase FHJ82_RS19085 ENOG4105CDU Replicative dna helicase FHJ82_RS19105 ENOG4105EDW glycosyl transferase, family 39 FHJ82_RS19110 ENOG4107QPH glycogen) synthase FHJ82_RS19120 ENOG4108HH9 Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR FHJ82_RS19130 ENOG4105CPK Glycosyl transferase (Group 1 FHJ82_RS19150 ENOG4105BZR domain protein FHJ82_RS19155 ENOG4108XMW Membrane FHJ82_RS19170 ENOG4105KVH Transcriptional regulator FHJ82_RS19175 ENOG4105E2M Manganese-dependent inorganic pyrophosphatase FHJ82_RS19180 ENOG4108UZ3 Transporter FHJ82_RS19185 ENOG4105EDQ levansucrase EC 2.4.1.10 FHJ82_RS19190 ENOG4108HKT sucrose-6-phosphate hydrolase FHJ82_RS19215 ENOG4108TVJ Nitroreductase FHJ82_RS19220 ENOG4105FS7 Transcriptional regulator FHJ82_RS19230 ENOG4108U05 Transcriptional regulator FHJ82_RS19235 ENOG41082BV acetyltransferase FHJ82_RS19245 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase FHJ82_RS19250 ENOG4105CMU LysR family (Transcriptional regulator FHJ82_RS19255 ENOG4105DTD Dehydrogenase FHJ82_RS19265 ENOG4107Y9U Membrane FHJ82_RS19270 ENOG4105C7Z Conserved Protein FHJ82_RS19295 ENOG4105C7Z Conserved Protein FHJ82_RS19300 ENOG4107FCW Abortive infection protein FHJ82_RS19310 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase FHJ82_RS19320 ENOG4105CGK Exodeoxyribonuclease III FHJ82_RS19325 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FHJ82_RS19335 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) FHJ82_RS19340 ENOG4108UUM single-stranded DNA-binding protein FHJ82_RS19345 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) FHJ82_RS19350 ENOG4105C3G gtp-binding protein FHJ82_RS19355 ENOG4108J2R molybdopterin oxidoreductase FHJ82_RS19360 ENOG4105VDK protein, conserved in bacteria FHJ82_RS19375 ENOG4108ZDA Sporulation protein YyaC FHJ82_RS19380 ENOG4105FA0 parb-like partition protein FHJ82_RS19385 ENOG4107QJE Chromosome Partitioning Protein FHJ82_RS19400 ENOG4105CWE NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) FHJ82_RS19405 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) FHJ82_RS19420 ENOG4105M7T RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)