locus-tag	class	description
AZK53_RS00075	COG1982	Orn Lys Arg decarboxylase major
AZK53_RS00080	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AZK53_RS00085	COG3870	Protein conserved in bacteria
AZK53_RS00090	COG0470	DNA polymerase III
AZK53_RS00095	COG1774	PSP1 C-terminal conserved region
AZK53_RS00100	COG4467	Involved in initiation control of chromosome replication
AZK53_RS00105	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AZK53_RS00110	COG2827	Endonuclease containing a URI domain
AZK53_RS00115	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AZK53_RS00120	COG2002	toxin-antitoxin pair type II binding
AZK53_RS00130	COG0084	hydrolase, TatD family'
AZK53_RS00140	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AZK53_RS00150	COG4466	Protein conserved in bacteria
AZK53_RS00165	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AZK53_RS00170	COG0251	oxidation-reduction process
AZK53_RS00175	COG2088	sporulation resulting in formation of a cellular spore
AZK53_RS00180	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AZK53_RS00190	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AZK53_RS00195	COG0193	aminoacyl-tRNA hydrolase activity
AZK53_RS00205	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AZK53_RS00210	COG2002	toxin-antitoxin pair type II binding
AZK53_RS00215	COG2244	polysaccharide biosynthetic process
AZK53_RS00220	COG3956	TIGRFAM MazG family protein
AZK53_RS00225	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AZK53_RS00240	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AZK53_RS00245	COG1098	S1 RNA binding domain
AZK53_RS00265	COG2304	oxidoreductase activity
AZK53_RS00270	COG0515	serine threonine protein kinase
AZK53_RS00275	COG0037	tRNA processing
AZK53_RS00280	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AZK53_RS00285	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AZK53_RS00290	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AZK53_RS00295	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AZK53_RS00300	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AZK53_RS00305	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AZK53_RS00310	COG0512	Glutamine amidotransferase of anthranilate synthase
AZK53_RS00315	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AZK53_RS00320	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AZK53_RS00325	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AZK53_RS00330	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AZK53_RS00355	COG3880	PFAM UvrB UvrC protein
AZK53_RS00360	COG3869	Catalyzes the specific phosphorylation of arginine residues in
AZK53_RS00365	COG0542	response to heat
AZK53_RS00370	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AZK53_RS00375	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
AZK53_RS00380	COG4956	integral membrane protein (PIN domain superfamily)
AZK53_RS00385	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AZK53_RS00395	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AZK53_RS00400	COG1045	serine acetyltransferase
AZK53_RS00405	COG0215	cysteine-tRNA ligase activity
AZK53_RS00415	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AZK53_RS00420	COG3688	RNA-binding protein containing a PIN domain
AZK53_RS00430	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AZK53_RS00435	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AZK53_RS00440	COG0250	Participates in transcription elongation, termination and antitermination
AZK53_RS00445	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AZK53_RS00450	COG0081	regulation of translation
AZK53_RS00455	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AZK53_RS00460	COG0222	ribosome binding
AZK53_RS00465	COG2813	Specifically methylates the guanine in position
AZK53_RS00470	COG0085	RNA polymerase activity
AZK53_RS00480	COG1358	cellular component organization or biogenesis
AZK53_RS00485	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AZK53_RS00490	COG0049	tRNA binding
AZK53_RS00500	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AZK53_RS00505	COG0051	transcription antitermination factor activity, RNA binding
AZK53_RS00510	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AZK53_RS00515	COG0088	Forms part of the polypeptide exit tunnel
AZK53_RS00520	COG0089	rRNA binding
AZK53_RS00525	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AZK53_RS00530	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AZK53_RS00535	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AZK53_RS00545	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AZK53_RS00550	COG0255	Belongs to the universal ribosomal protein uL29 family
AZK53_RS00555	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AZK53_RS00560	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AZK53_RS00575	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AZK53_RS00590	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AZK53_RS00595	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AZK53_RS00600	COG1841	ribosomal large subunit assembly
AZK53_RS00610	COG0201	protein transport
AZK53_RS00615	COG0563	adenylate kinase activity
AZK53_RS00620	COG0024	Methionine aminopeptidase
AZK53_RS00625	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AZK53_RS00630	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AZK53_RS00635	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AZK53_RS00645	COG0202	RNA polymerase activity
AZK53_RS00650	COG0203	ribosomal protein L17
AZK53_RS00655	COG1122	ATPase activity
AZK53_RS00660	COG1122	ATPase activity
AZK53_RS00665	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AZK53_RS00670	COG0101	tRNA pseudouridine synthase activity
AZK53_RS00675	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AZK53_RS00690	COG0860	N-Acetylmuramoyl-L-alanine amidase
AZK53_RS00695	COG0489	protein tyrosine kinase activity
AZK53_RS00700	COG0583	DNA-binding transcription factor activity
AZK53_RS00710	COG2194	sulfuric ester hydrolase activity
AZK53_RS00715	COG0726	polysaccharide deacetylase
AZK53_RS00790	COG1595	DNA-templated transcription, initiation
AZK53_RS00795	COG5662	AntiSigma factor
AZK53_RS00800	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AZK53_RS00810	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AZK53_RS00815	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AZK53_RS00825	COG3103	Sh3 type 3 domain protein
AZK53_RS00825	COG1388	LysM domain
AZK53_RS00825	COG0791	NLP P60 protein
AZK53_RS00830	COG2213	PTS system mannitol-specific
AZK53_RS00830	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AZK53_RS00835	COG3711	transcriptional antiterminator
AZK53_RS00840	COG0246	Mannitol dehydrogenase
AZK53_RS00850	COG1376	ErfK ybiS ycfS ynhG family protein
AZK53_RS00855	COG1970	mechanosensitive ion channel activity
AZK53_RS00860	COG1368	sulfuric ester hydrolase activity
AZK53_RS00880	COG1177	transmembrane transport
AZK53_RS00885	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AZK53_RS00895	COG0745	RESPONSE REGULATOR receiver
AZK53_RS00900	COG5002	protein histidine kinase activity
AZK53_RS00915	COG3976	FMN-binding domain protein
AZK53_RS00915	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AZK53_RS00920	COG1181	Belongs to the D-alanine--D-alanine ligase family
AZK53_RS00925	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AZK53_RS00930	COG0513	Belongs to the DEAD box helicase family
AZK53_RS00935	COG4294	response to UV
AZK53_RS00940	COG0705	Rhomboid family
AZK53_RS00945	COG0736	holo-[acyl-carrier-protein] synthase activity
AZK53_RS00950	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AZK53_RS00955	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AZK53_RS00960	COG0864	Transcriptional regulator
AZK53_RS00965	COG2337	Toxic component of a toxin-antitoxin (TA) module
AZK53_RS00970	COG1366	Belongs to the anti-sigma-factor antagonist family
AZK53_RS00975	COG1366	Belongs to the anti-sigma-factor antagonist family
AZK53_RS00980	COG2172	sigma factor antagonist activity
AZK53_RS00985	COG2208	phosphoserine phosphatase activity
AZK53_RS00990	COG1366	Belongs to the anti-sigma-factor antagonist family
AZK53_RS01000	COG1191	sigma factor activity
AZK53_RS01005	COG2208	phosphoserine phosphatase activity
AZK53_RS01010	COG2183	response to ionizing radiation
AZK53_RS01100	COG0802	atpase or kinase
AZK53_RS01105	COG1214	PFAM Peptidase M22, glycoprotease
AZK53_RS01110	COG0456	acetyltransferase
AZK53_RS01120	COG0488	(ABC) transporter
AZK53_RS01125	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AZK53_RS01130	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AZK53_RS01135	COG0805	protein transport
AZK53_RS01145	COG1266	CAAX protease self-immunity
AZK53_RS01150	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AZK53_RS01160	COG0714	Associated with various cellular activities
AZK53_RS01165	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
AZK53_RS01170	COG1305	Transglutaminase-like
AZK53_RS01175	COG0519	Catalyzes the synthesis of GMP from XMP
AZK53_RS01175	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AZK53_RS01180	COG2252	PERMEase
AZK53_RS01235	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AZK53_RS01240	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AZK53_RS01245	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AZK53_RS01250	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AZK53_RS01255	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AZK53_RS01260	COG0047	phosphoribosylformylglycinamidine synthase activity
AZK53_RS01265	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AZK53_RS01270	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AZK53_RS01275	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AZK53_RS01280	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AZK53_RS01285	COG0138	bifunctional purine biosynthesis protein purh
AZK53_RS01290	COG0151	Belongs to the GarS family
AZK53_RS01300	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AZK53_RS01305	COG4496	protein, YerC YecD
AZK53_RS01310	COG0423	glycine-tRNA ligase activity
AZK53_RS01320	COG0210	DNA helicase
AZK53_RS01330	COG4851	CamS sex pheromone cAM373 precursor
AZK53_RS01340	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AZK53_RS01345	COG0154	amidase activity
AZK53_RS01355	COG1597	lipid kinase activity
AZK53_RS01365	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AZK53_RS01375	COG0166	Belongs to the GPI family
AZK53_RS01380	COG1744	ABC transporter substrate-binding protein PnrA-like
AZK53_RS01385	COG3852	Histidine kinase
AZK53_RS01390	COG0024	Methionine aminopeptidase
AZK53_RS01395	COG2706	6-phosphogluconolactonase activity
AZK53_RS01405	COG0789	Transcriptional regulator
AZK53_RS01405	COG4978	Transcriptional regulator
AZK53_RS01410	COG2814	Major facilitator Superfamily
AZK53_RS01420	COG1876	peptidase activity
AZK53_RS01425	COG1126	abc transporter atp-binding protein
AZK53_RS01430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZK53_RS01435	COG0765	amino acid transport
AZK53_RS01440	COG0765	amino acid transport
AZK53_RS01445	COG1113	amino acid transport
AZK53_RS01450	COG2733	membrane
AZK53_RS01455	COG3212	peptidase
AZK53_RS01460	COG3212	peptidase
AZK53_RS01465	COG3850	Histidine kinase
AZK53_RS01465	COG5002	protein histidine kinase activity
AZK53_RS01470	COG0745	RESPONSE REGULATOR receiver
AZK53_RS01475	COG0671	phosphoesterase, PA-phosphatase related
AZK53_RS01480	COG1764	response to oxidative stress
AZK53_RS01485	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AZK53_RS01495	COG2259	Doxx family
AZK53_RS01500	COG0693	protein deglycase activity
AZK53_RS01510	COG2318	DinB family
AZK53_RS01520	COG1115	amino acid carrier protein
AZK53_RS01535	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
AZK53_RS01540	COG0598	Magnesium transport protein CorA
AZK53_RS01545	COG3290	protein histidine kinase activity
AZK53_RS01550	COG4565	transcriptional regulatory protein
AZK53_RS01565	COG4191	Histidine kinase
AZK53_RS01570	COG0513	Belongs to the DEAD box helicase family
AZK53_RS01590	COG4842	Belongs to the WXG100 family
AZK53_RS01595	COG5417	Belongs to the EsaB family
AZK53_RS01600	COG4499	WXG100 protein secretion system (Wss), protein YukC
AZK53_RS01605	COG0433	COG0433 Predicted ATPase
AZK53_RS01605	COG1674	ftsk spoiiie
AZK53_RS01610	COG1511	domain protein
AZK53_RS01625	COG2356	endonuclease I
AZK53_RS01635	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AZK53_RS01650	COG0488	(ABC) transporter
AZK53_RS01655	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AZK53_RS01660	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
AZK53_RS01670	COG1959	2 iron, 2 sulfur cluster binding
AZK53_RS01675	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AZK53_RS01675	COG1017	nitric oxide dioxygenase activity
AZK53_RS01685	COG0693	protein deglycase activity
AZK53_RS01690	COG2340	Cysteine-rich secretory protein family
AZK53_RS01695	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AZK53_RS01700	COG4840	Belongs to the UPF0435 family
AZK53_RS01705	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AZK53_RS01710	COG4980	gas vesicle protein
AZK53_RS01715	COG1295	ribonuclease BN
AZK53_RS01720	COG2217	Heavy metal translocating P-type atpase
AZK53_RS01730	COG0640	Transcriptional regulator
AZK53_RS01740	COG0477	Major facilitator Superfamily
AZK53_RS01745	COG3479	Phenolic acid decarboxylase
AZK53_RS01755	COG3871	stress protein (general stress protein 26)
AZK53_RS01760	COG0387	Pfam Sodium calcium exchanger
AZK53_RS01770	COG0535	radical SAM domain protein
AZK53_RS01790	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AZK53_RS01800	COG1113	amino acid transport
AZK53_RS01805	COG5002	protein histidine kinase activity
AZK53_RS01820	COG1090	epimerase
AZK53_RS01830	COG4221	oxidoreductase activity
AZK53_RS01850	COG1988	membrane-bound metal-dependent
AZK53_RS01855	COG1194	a g-specific adenine glycosylase
AZK53_RS01865	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_RS01880	COG3557	Belongs to the UPF0374 family
AZK53_RS01885	COG1132	(ABC) transporter
AZK53_RS01890	COG4129	membrane
AZK53_RS01895	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AZK53_RS01900	COG4555	ABC transporter
AZK53_RS01920	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AZK53_RS01925	COG0735	belongs to the Fur family
AZK53_RS02040	COG3382	B3 4 domain protein
AZK53_RS02055	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AZK53_RS02060	COG2766	serine protein kinase
AZK53_RS02075	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AZK53_RS02090	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AZK53_RS02100	COG1968	undecaprenyl-diphosphatase activity
AZK53_RS02105	COG1301	dicarboxylic acid transport
AZK53_RS02110	COG0628	permease
AZK53_RS02115	COG0586	Pfam SNARE associated Golgi protein
AZK53_RS02120	COG2217	Heavy metal translocating P-type atpase
AZK53_RS02125	COG0531	amino acid
AZK53_RS02140	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AZK53_RS02145	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AZK53_RS02150	COG3842	ATPase activity
AZK53_RS02155	COG1175	transmembrane transport
AZK53_RS02170	COG0584	glycerophosphoryl diester phosphodiesterase
AZK53_RS02190	COG4948	Mandelate Racemase Muconate Lactonizing
AZK53_RS02235	COG3584	3D domain protein
AZK53_RS02235	COG3583	domain protein
AZK53_RS02240	COG1876	peptidase activity
AZK53_RS02245	COG3103	Sh3 type 3 domain protein
AZK53_RS02250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AZK53_RS02250	COG0456	acetyltransferase
AZK53_RS02260	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AZK53_RS02280	COG1609	Transcriptional regulator
AZK53_RS02285	COG2814	Major facilitator Superfamily
AZK53_RS02290	COG0673	inositol 2-dehydrogenase activity
AZK53_RS02315	COG1609	Transcriptional regulator
AZK53_RS02330	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AZK53_RS02335	COG1522	sequence-specific DNA binding
AZK53_RS02350	COG2814	Major facilitator Superfamily
AZK53_RS02355	COG1309	transcriptional regulator
AZK53_RS02360	COG1187	pseudouridine synthase activity
AZK53_RS02370	COG1942	4-Oxalocrotonate Tautomerase
AZK53_RS02375	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AZK53_RS02380	COG0747	negative chemotaxis
AZK53_RS02395	COG0084	hydrolase, TatD family'
AZK53_RS02400	COG2962	Rard protein
AZK53_RS02410	COG0628	permease
AZK53_RS02425	COG0604	alcohol dehydrogenase
AZK53_RS02430	COG1620	l-lactate permease
AZK53_RS02440	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AZK53_RS02445	COG0840	transmembrane signaling receptor activity
AZK53_RS02450	COG0564	pseudouridine synthase activity
AZK53_RS02460	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AZK53_RS02465	COG1376	ErfK ybiS ycfS ynhG family protein
AZK53_RS02470	COG3153	acetyltransferase
AZK53_RS02470	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AZK53_RS02475	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AZK53_RS02480	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AZK53_RS02490	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AZK53_RS02495	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AZK53_RS02500	COG1268	BioY protein
AZK53_RS02510	COG2719	SpoVR family
AZK53_RS02520	COG1959	2 iron, 2 sulfur cluster binding
AZK53_RS02525	COG0604	alcohol dehydrogenase
AZK53_RS02535	COG1126	abc transporter atp-binding protein
AZK53_RS02540	COG0765	amino acid transport
AZK53_RS02545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZK53_RS02550	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AZK53_RS02555	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AZK53_RS02565	COG0352	thiamine-phosphate diphosphorylase activity
AZK53_RS02570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZK53_RS02585	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AZK53_RS02590	COG0351	phosphomethylpyrimidine kinase
AZK53_RS02605	COG0702	epimerase
AZK53_RS02610	COG1253	flavin adenine dinucleotide binding
AZK53_RS02625	COG3842	ATPase activity
AZK53_RS02630	COG2508	Transcriptional regulator
AZK53_RS02645	COG0189	ligase activity
AZK53_RS02650	COG0189	ligase activity
AZK53_RS02660	COG3679	Belongs to the UPF0342 family
AZK53_RS02665	COG0561	phosphatase activity
AZK53_RS02670	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AZK53_RS02675	COG0318	PFAM AMP-dependent synthetase and ligase
AZK53_RS02680	COG1024	Enoyl-CoA hydratase
AZK53_RS02695	COG4152	abc transporter atp-binding protein
AZK53_RS02700	COG1668	transmembrane transport
AZK53_RS02705	COG3481	metal-dependent phosphohydrolase, HD sub domain
AZK53_RS02715	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AZK53_RS02730	COG1846	Transcriptional regulator
AZK53_RS02745	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AZK53_RS02750	COG1695	Transcriptional regulator
AZK53_RS02755	COG2153	protein acetylation
AZK53_RS02760	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AZK53_RS02760	COG2755	lipolytic protein G-D-S-L family
AZK53_RS02765	COG0537	adenosine 5'-monophosphoramidase activity
AZK53_RS02770	COG1131	(ABC) transporter
AZK53_RS02775	COG4473	ABC transporter
AZK53_RS02785	COG1473	amidohydrolase
AZK53_RS02790	COG0671	phosphoesterase, PA-phosphatase related
AZK53_RS02795	COG3069	C4-dicarboxylate transmembrane transporter activity
AZK53_RS02800	COG2329	Antibiotic biosynthesis monooxygenase
AZK53_RS02805	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AZK53_RS02810	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AZK53_RS02815	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AZK53_RS02820	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AZK53_RS02825	COG1309	transcriptional regulator
AZK53_RS02830	COG0768	penicillin binding
AZK53_RS02840	COG2972	Histidine kinase
AZK53_RS02850	COG1234	tRNA 3'-trailer cleavage
AZK53_RS02855	COG0095	Lipoate-protein ligase
AZK53_RS02860	COG0318	PFAM AMP-dependent synthetase and ligase
AZK53_RS02865	COG1024	Enoyl-CoA hydratase
AZK53_RS02980	COG0501	Belongs to the peptidase M48B family
AZK53_RS02985	COG2224	Isocitrate lyase
AZK53_RS02995	COG4946	Tricorn protease homolog
AZK53_RS02995	COG1506	peptidase
AZK53_RS02995	COG0823	Involved in the tonB-independent uptake of proteins
AZK53_RS03000	COG0398	Pfam SNARE associated Golgi protein
AZK53_RS03005	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_RS03010	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AZK53_RS03015	COG1074	ATP-dependent DNA helicase activity
AZK53_RS03020	COG0420	3'-5' exonuclease activity
AZK53_RS03025	COG0419	ATPase involved in DNA repair
AZK53_RS03030	COG1403	HNH endonuclease
AZK53_RS03065	COG2311	Membrane
AZK53_RS03080	COG0367	asparagine synthase
AZK53_RS03095	COG1562	ergosterol biosynthetic process
AZK53_RS03105	COG1874	Beta-galactosidase
AZK53_RS03105	COG0366	Alpha amylase catalytic
AZK53_RS03110	COG1609	Transcriptional regulator
AZK53_RS03115	COG1012	belongs to the aldehyde dehydrogenase family
AZK53_RS03120	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AZK53_RS03125	COG4187	Peptidase family M20/M25/M40
AZK53_RS03130	COG0833	amino acid
AZK53_RS03135	COG3829	transcription factor binding
AZK53_RS03140	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_RS03145	COG1666	GTP binding
AZK53_RS03150	COG2996	Protein conserved in bacteria
AZK53_RS03155	COG1307	EDD domain protein, DegV family
AZK53_RS03160	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AZK53_RS03170	COG0561	phosphatase activity
AZK53_RS03175	COG2151	metal-sulfur cluster biosynthetic enzyme
AZK53_RS03180	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AZK53_RS03185	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AZK53_RS03190	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AZK53_RS03195	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AZK53_RS03215	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AZK53_RS03230	COG0542	response to heat
AZK53_RS03245	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AZK53_RS03250	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
AZK53_RS03255	COG2084	Dehydrogenase
AZK53_RS03265	COG2267	carboxylic ester hydrolase activity
AZK53_RS03285	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AZK53_RS03290	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AZK53_RS03295	COG5504	Zn-dependent protease
AZK53_RS03300	COG0444	Belongs to the ABC transporter superfamily
AZK53_RS03305	COG4608	Belongs to the ABC transporter superfamily
AZK53_RS03315	COG0601	transmembrane transport
AZK53_RS03330	COG0180	Tryptophanyl-tRNA synthetase
AZK53_RS03340	COG4166	transmembrane transport
AZK53_RS03345	COG0601	transmembrane transport
AZK53_RS03350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZK53_RS03355	COG0444	Belongs to the ABC transporter superfamily
AZK53_RS03360	COG4608	Belongs to the ABC transporter superfamily
AZK53_RS03365	COG0456	acetyltransferase
AZK53_RS03370	COG1113	amino acid transport
AZK53_RS03375	COG0531	amino acid
AZK53_RS03380	COG1393	Belongs to the ArsC family
AZK53_RS03385	COG0583	DNA-binding transcription factor activity
AZK53_RS03400	COG0861	Integral membrane protein TerC family
AZK53_RS03410	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AZK53_RS03420	COG1164	Oligoendopeptidase f
AZK53_RS03430	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AZK53_RS03435	COG2346	COG2346, Truncated hemoglobins
AZK53_RS03440	COG0741	lytic transglycosylase activity
AZK53_RS03445	COG4116	CYTH
AZK53_RS03455	COG2357	RelA SpoT domain protein
AZK53_RS03465	COG0564	pseudouridine synthase activity
AZK53_RS03475	COG2239	Acts as a magnesium transporter
AZK53_RS03480	COG0475	glutathione-regulated potassium exporter activity
AZK53_RS03480	COG0569	domain protein
AZK53_RS03525	COG0210	DNA helicase
AZK53_RS03535	COG2323	membrane
AZK53_RS03540	COG2153	protein acetylation
AZK53_RS03550	COG2382	esterase
AZK53_RS03560	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AZK53_RS03570	COG1737	Transcriptional regulator
AZK53_RS03575	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AZK53_RS03580	COG1070	Carbohydrate kinase
AZK53_RS03585	COG1953	Uracil, thiamine, allantoin
AZK53_RS03605	COG1522	sequence-specific DNA binding
AZK53_RS03615	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AZK53_RS03630	COG3142	Participates in the control of copper homeostasis
AZK53_RS03635	COG1113	amino acid transport
AZK53_RS03645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZK53_RS03650	COG1309	transcriptional regulator
AZK53_RS03655	COG3711	transcriptional antiterminator
AZK53_RS03655	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AZK53_RS03660	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AZK53_RS03665	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AZK53_RS03670	COG1447	Phosphotransferase system cellobiose-specific component IIA
AZK53_RS03675	COG1486	melibiose metabolic process
AZK53_RS03680	COG3275	phosphorelay sensor kinase activity
AZK53_RS03685	COG3279	Response regulator of the LytR AlgR family
AZK53_RS03695	COG1346	cytolysis
AZK53_RS03705	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AZK53_RS03710	COG0243	molybdopterin cofactor binding
AZK53_RS03715	COG2223	nitrite transmembrane transporter activity
AZK53_RS03720	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AZK53_RS03735	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AZK53_RS03745	COG0028	Belongs to the TPP enzyme family
AZK53_RS03745	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
AZK53_RS03750	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AZK53_RS03750	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AZK53_RS03760	COG3527	Alpha-acetolactate decarboxylase
AZK53_RS03765	COG0028	Belongs to the TPP enzyme family
AZK53_RS03770	COG4895	conserved protein (DUF2196)
AZK53_RS03780	COG1733	regulation of RNA biosynthetic process
AZK53_RS03785	COG2814	Major facilitator Superfamily
AZK53_RS03790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZK53_RS03810	COG3052	prosthetic group binding
AZK53_RS03825	COG0784	Response regulator, receiver
AZK53_RS03830	COG4191	Histidine kinase
AZK53_RS03835	COG2066	Belongs to the glutaminase family
AZK53_RS03840	COG1115	amino acid carrier protein
AZK53_RS03845	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AZK53_RS03855	COG4297	protein containing double-stranded beta helix domain
AZK53_RS03860	COG0531	amino acid
AZK53_RS03870	COG1607	acyl-coa hydrolase
AZK53_RS03875	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AZK53_RS03890	COG0390	transport system, permease component
AZK53_RS03895	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AZK53_RS03910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZK53_RS03915	COG1136	(ABC) transporter
AZK53_RS03920	COG0577	efflux transmembrane transporter activity
AZK53_RS03930	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AZK53_RS03950	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AZK53_RS03955	COG0833	amino acid
AZK53_RS03965	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AZK53_RS03970	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AZK53_RS03980	COG0861	Integral membrane protein TerC family
AZK53_RS03985	COG1301	dicarboxylic acid transport
AZK53_RS03990	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AZK53_RS03995	COG3290	protein histidine kinase activity
AZK53_RS04035	COG1476	TRANSCRIPTIONal
AZK53_RS04045	COG1368	sulfuric ester hydrolase activity
AZK53_RS04060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZK53_RS04065	COG2040	homocysteine
AZK53_RS04070	COG0179	Fumarylacetoacetate (FAA) hydrolase
AZK53_RS04085	COG2851	Citrate transporter
AZK53_RS04090	COG3290	protein histidine kinase activity
AZK53_RS04095	COG4565	transcriptional regulatory protein
AZK53_RS04100	COG3181	Tripartite tricarboxylate transporter family receptor
AZK53_RS04105	COG0583	DNA-binding transcription factor activity
AZK53_RS04110	COG3180	Ammonia monooxygenase
AZK53_RS04115	COG2226	methyltransferase
AZK53_RS04125	COG4175	Glycine betaine
AZK53_RS04125	COG0517	IMP dehydrogenase activity
AZK53_RS04130	COG2113	Glycine betaine
AZK53_RS04135	COG1309	transcriptional regulator
AZK53_RS04140	COG1012	belongs to the aldehyde dehydrogenase family
AZK53_RS04155	COG0531	amino acid
AZK53_RS04160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AZK53_RS04165	COG1464	Belongs to the NlpA lipoprotein family
AZK53_RS04170	COG2011	ABC-type metal ion transport system permease component
AZK53_RS04175	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AZK53_RS04190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZK53_RS04200	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AZK53_RS04205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AZK53_RS04210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AZK53_RS04235	COG1737	Transcriptional regulator
AZK53_RS04240	COG1263	PTS System
AZK53_RS04240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AZK53_RS04250	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AZK53_RS04255	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AZK53_RS04260	COG1116	anion transmembrane transporter activity
AZK53_RS04265	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZK53_RS04270	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZK53_RS04280	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AZK53_RS04285	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AZK53_RS04290	COG1733	regulation of RNA biosynthetic process
AZK53_RS04325	COG1511	domain protein
AZK53_RS04335	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AZK53_RS04340	COG1733	regulation of RNA biosynthetic process
AZK53_RS04345	COG4221	oxidoreductase activity
AZK53_RS04345	COG0604	alcohol dehydrogenase
AZK53_RS04345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AZK53_RS04345	COG3321	synthase
AZK53_RS04350	COG1132	(ABC) transporter
AZK53_RS04355	COG1132	(ABC) transporter
AZK53_RS04365	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AZK53_RS04370	COG3162	membrane
AZK53_RS04380	COG1414	Transcriptional regulator
AZK53_RS04385	COG0656	L-ascorbic acid biosynthetic process
AZK53_RS04390	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
AZK53_RS04395	COG1846	Transcriptional regulator
AZK53_RS04400	COG1566	PFAM secretion protein HlyD family protein
AZK53_RS04405	COG2814	Major facilitator Superfamily
AZK53_RS04410	COG0655	NAD(P)H dehydrogenase (quinone) activity
AZK53_RS04425	COG1609	Transcriptional regulator
AZK53_RS04430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AZK53_RS04440	COG1129	ABC transporter
AZK53_RS04445	COG1172	Belongs to the binding-protein-dependent transport system permease family
AZK53_RS04450	COG1879	ABC-type sugar transport system periplasmic component
AZK53_RS04455	COG3584	3D domain protein
AZK53_RS04455	COG3583	domain protein
AZK53_RS04460	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AZK53_RS04465	COG1653	transport
AZK53_RS04510	COG0745	RESPONSE REGULATOR receiver
AZK53_RS04515	COG5002	protein histidine kinase activity
AZK53_RS04525	COG2267	carboxylic ester hydrolase activity
AZK53_RS04535	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AZK53_RS04550	COG0402	S-adenosylhomocysteine deaminase activity
AZK53_RS04555	COG2252	PERMEase
AZK53_RS04560	COG1609	Transcriptional regulator
AZK53_RS04565	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AZK53_RS04570	COG1012	belongs to the aldehyde dehydrogenase family
AZK53_RS04580	COG0710	3-dehydroquinate dehydratase activity
AZK53_RS04585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AZK53_RS04585	COG1263	PTS System
AZK53_RS04590	COG0366	Alpha amylase catalytic
AZK53_RS04595	COG2188	Transcriptional regulator
AZK53_RS04605	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AZK53_RS04610	COG1984	allophanate hydrolase subunit 2
AZK53_RS04615	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AZK53_RS04620	COG1914	H( )-stimulated, divalent metal cation uptake system
AZK53_RS04625	COG1272	protein, Hemolysin III
AZK53_RS04640	COG0778	Nitroreductase
AZK53_RS04645	COG0628	permease
AZK53_RS04670	COG2271	Major facilitator Superfamily
AZK53_RS04675	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AZK53_RS04680	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AZK53_RS04685	COG1012	belongs to the aldehyde dehydrogenase family
AZK53_RS04695	COG0402	S-adenosylhomocysteine deaminase activity
AZK53_RS04700	COG1278	Cold shock
AZK53_RS04705	COG2910	NAD(P)H-binding
AZK53_RS04710	COG0673	inositol 2-dehydrogenase activity
AZK53_RS04715	COG0450	alkyl hydroperoxide reductase
AZK53_RS04720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AZK53_RS04735	COG5001	Diguanylate cyclase
AZK53_RS04735	COG3706	GGDEF domain
AZK53_RS04735	COG4251	negative regulation of phosphorylation
AZK53_RS04735	COG2203	Gaf domain
AZK53_RS04740	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AZK53_RS04820	COG1649	PFAM Uncharacterised BCR, COG1649
AZK53_RS04825	COG1737	Transcriptional regulator
AZK53_RS04845	COG1486	melibiose metabolic process
AZK53_RS04855	COG1447	Phosphotransferase system cellobiose-specific component IIA
AZK53_RS04865	COG2971	BadF BadG BcrA BcrD
AZK53_RS04870	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AZK53_RS04885	COG3037	sugar-specific permease SgaT UlaA
AZK53_RS04890	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AZK53_RS04890	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AZK53_RS04900	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AZK53_RS04915	COG1376	ErfK ybiS ycfS ynhG family protein
AZK53_RS04920	COG4106	trans-aconitate 2-methyltransferase activity
AZK53_RS04925	COG0583	DNA-binding transcription factor activity
AZK53_RS04935	COG0667	Aldo Keto reductase
AZK53_RS04950	COG0154	amidase activity
AZK53_RS04960	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AZK53_RS04995	COG2200	EAL domain
AZK53_RS04995	COG2199	diguanylate cyclase activity
AZK53_RS05005	COG1733	regulation of RNA biosynthetic process
AZK53_RS05020	COG0385	Bile acid
AZK53_RS05030	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AZK53_RS05035	COG4191	Histidine kinase
AZK53_RS05040	COG0784	Response regulator, receiver
AZK53_RS05055	COG0791	NLP P60 protein
AZK53_RS05055	COG1388	LysM domain
AZK53_RS05065	COG2385	sporulation resulting in formation of a cellular spore
AZK53_RS05070	COG0656	L-ascorbic acid biosynthetic process
AZK53_RS05080	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AZK53_RS05085	COG4948	Mandelate Racemase Muconate Lactonizing
AZK53_RS05105	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AZK53_RS05120	COG0477	Major facilitator Superfamily
AZK53_RS05125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AZK53_RS05135	COG0640	Transcriptional regulator
AZK53_RS05140	COG5658	integral membrane protein
AZK53_RS05160	COG3300	MHYT domain
AZK53_RS05160	COG5001	Diguanylate cyclase
AZK53_RS05165	COG0302	gtp cyclohydrolase
AZK53_RS05180	COG3300	MHYT domain
AZK53_RS05180	COG5001	Diguanylate cyclase
AZK53_RS05185	COG0531	amino acid
AZK53_RS05200	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AZK53_RS05235	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AZK53_RS05240	COG1396	sequence-specific DNA binding
AZK53_RS05260	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AZK53_RS05280	COG1215	transferase activity, transferring glycosyl groups
AZK53_RS05300	COG2247	cell wall binding repeat
AZK53_RS05300	COG2385	sporulation resulting in formation of a cellular spore
AZK53_RS05300	COG2247	cell wall binding repeat
AZK53_RS05300	COG2385	sporulation resulting in formation of a cellular spore
AZK53_RS05315	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AZK53_RS05320	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AZK53_RS05325	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AZK53_RS05330	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AZK53_RS05335	COG0728	peptidoglycan biosynthetic process
AZK53_RS05340	COG0438	transferase activity, transferring glycosyl groups
AZK53_RS05365	COG0110	maltose O-acetyltransferase activity
AZK53_RS05375	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AZK53_RS05390	COG1482	cell wall glycoprotein biosynthetic process
AZK53_RS05395	COG3944	biosynthesis protein
AZK53_RS05400	COG0489	protein tyrosine kinase activity
AZK53_RS05425	COG4464	protein tyrosine phosphatase activity
AZK53_RS05430	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AZK53_RS05435	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AZK53_RS05465	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AZK53_RS05470	COG1682	transport, permease protein
AZK53_RS05475	COG1134	teichoic acid transport
AZK53_RS05485	COG1316	TRANSCRIPTIONal
AZK53_RS05510	COG0028	Belongs to the TPP enzyme family
AZK53_RS05515	COG0069	glutamate synthase activity
AZK53_RS05525	COG2084	Dehydrogenase
AZK53_RS05560	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AZK53_RS05565	COG2146	nitrite reductase [NAD(P)H] activity
AZK53_RS05575	COG2116	formate transmembrane transporter activity
AZK53_RS05585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AZK53_RS05590	COG4975	Glucose uptake
AZK53_RS05605	COG0534	Mate efflux family protein
AZK53_RS05615	COG1316	TRANSCRIPTIONal
AZK53_RS05625	COG0598	Magnesium transport protein CorA
AZK53_RS05630	COG1404	Belongs to the peptidase S8 family
AZK53_RS05650	COG4821	SIS domain
AZK53_RS05655	COG2188	Transcriptional regulator
AZK53_RS05660	COG0363	glucosamine-6-phosphate deaminase activity
AZK53_RS05665	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AZK53_RS05670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AZK53_RS05670	COG1263	PTS System
AZK53_RS05670	COG2190	(PTS) system
AZK53_RS05675	COG1811	Na channel or pump
AZK53_RS05680	COG3961	Belongs to the TPP enzyme family
AZK53_RS05715	COG1131	(ABC) transporter
AZK53_RS05720	COG1253	flavin adenine dinucleotide binding
AZK53_RS05725	COG0789	Transcriptional regulator
AZK53_RS05735	COG0346	lactoylglutathione lyase activity
AZK53_RS05740	COG2105	PFAM AIG2 family protein
AZK53_RS05740	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AZK53_RS05785	COG0456	acetyltransferase
AZK53_RS05790	COG1473	amidohydrolase
AZK53_RS05800	COG4187	Peptidase family M20/M25/M40
AZK53_RS05815	COG0456	acetyltransferase
AZK53_RS05815	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AZK53_RS05830	COG2252	PERMEase
AZK53_RS05840	COG3279	Response regulator of the LytR AlgR family
AZK53_RS05845	COG4555	ABC transporter
AZK53_RS05850	COG1668	transmembrane transport
AZK53_RS05860	COG0789	Transcriptional regulator
AZK53_RS05865	COG1846	Transcriptional regulator
AZK53_RS05870	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AZK53_RS05870	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AZK53_RS05890	COG1785	Belongs to the alkaline phosphatase family
AZK53_RS05895	COG3279	Response regulator of the LytR AlgR family
AZK53_RS05900	COG0784	Response regulator, receiver
AZK53_RS05900	COG2205	protein histidine kinase activity
AZK53_RS05905	COG0861	Integral membrane protein TerC family
AZK53_RS05910	COG1191	sigma factor activity
AZK53_RS05940	COG3243	poly(R)-hydroxyalkanoic acid synthase
AZK53_RS05955	COG2186	Transcriptional regulator
AZK53_RS05960	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AZK53_RS05970	COG0247	lactate metabolic process
AZK53_RS05975	COG1139	Iron-sulfur cluster binding protein
AZK53_RS05980	COG1556	Lactate utilization protein
AZK53_RS05985	COG5002	protein histidine kinase activity
AZK53_RS05990	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AZK53_RS05995	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AZK53_RS06000	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
AZK53_RS06005	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AZK53_RS06010	COG0436	Aminotransferase
AZK53_RS06015	COG1850	ribulose-bisphosphate carboxylase activity
AZK53_RS06020	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
AZK53_RS06025	COG0235	Class ii aldolase
AZK53_RS06030	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AZK53_RS06040	COG1129	ABC transporter
AZK53_RS06045	COG1172	Belongs to the binding-protein-dependent transport system permease family
AZK53_RS06070	COG1846	Transcriptional regulator
AZK53_RS06080	COG2801	Transposase and inactivated derivatives
AZK53_RS06090	COG4191	Histidine kinase
AZK53_RS06100	COG0542	response to heat
AZK53_RS06105	COG1757	Na H antiporter
AZK53_RS06115	COG0300	oxidoreductase activity
AZK53_RS06120	COG0697	spore germination
AZK53_RS06140	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AZK53_RS06145	COG0720	synthase
AZK53_RS06155	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AZK53_RS06160	COG0702	epimerase
AZK53_RS06170	COG4873	Protein conserved in bacteria
AZK53_RS06190	COG3773	Cell wall hydrolase
AZK53_RS06230	COG1410	methionine synthase
AZK53_RS06230	COG0646	methionine synthase
AZK53_RS06235	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AZK53_RS06235	COG0646	methionine synthase
AZK53_RS06240	COG3949	Membrane
AZK53_RS06250	COG0307	riboflavin synthase, alpha
AZK53_RS06260	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AZK53_RS06270	COG3711	transcriptional antiterminator
AZK53_RS06275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AZK53_RS06275	COG1263	PTS System
AZK53_RS06275	COG2190	(PTS) system
AZK53_RS06290	COG1346	cytolysis
AZK53_RS06300	COG0583	DNA-binding transcription factor activity
AZK53_RS06310	COG0456	acetyltransferase
AZK53_RS06315	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_RS06320	COG0778	Nitroreductase
AZK53_RS06325	COG0436	Aminotransferase
AZK53_RS06345	COG0784	Response regulator, receiver
AZK53_RS06345	COG0835	chemotaxis
AZK53_RS06355	COG1376	ErfK ybiS ycfS ynhG family protein
AZK53_RS06375	COG1408	metallophosphoesterase
AZK53_RS06380	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_RS06385	COG2200	EAL domain
AZK53_RS06400	COG4703	Protein of unknown function (DUF1797)
AZK53_RS06405	COG0517	IMP dehydrogenase activity
AZK53_RS06410	COG0583	DNA-binding transcription factor activity
AZK53_RS06415	COG2171	N-acyltransferase activity
AZK53_RS06420	COG1473	amidohydrolase
AZK53_RS06430	COG0668	transmembrane transport
AZK53_RS06435	COG0450	alkyl hydroperoxide reductase
AZK53_RS06440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AZK53_RS06445	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AZK53_RS06455	COG1132	(ABC) transporter
AZK53_RS06460	COG1132	(ABC) transporter
AZK53_RS06465	COG0569	domain protein
AZK53_RS06470	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AZK53_RS06475	COG5503	Protein of unknown function (DUF1447)
AZK53_RS06480	COG0561	phosphatase activity
AZK53_RS06500	COG0022	dehydrogenase e1 component
AZK53_RS06505	COG0508	dehydrogenase complex catalyzes the overall conversion of
AZK53_RS06525	COG1982	Orn Lys Arg decarboxylase major
AZK53_RS06530	COG4476	Belongs to the UPF0223 family
AZK53_RS06535	COG4493	Belongs to the UPF0637 family
AZK53_RS06545	COG0483	inositol monophosphate 1-phosphatase activity
AZK53_RS06555	COG1217	gtp-binding protein TYPA
AZK53_RS06570	COG4896	Protein conserved in bacteria
AZK53_RS06585	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AZK53_RS06590	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AZK53_RS06595	COG4838	Belongs to the UPF0358 family
AZK53_RS06600	COG0772	Belongs to the SEDS family
AZK53_RS06605	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AZK53_RS06610	COG1612	heme a metabolic process
AZK53_RS06615	COG0109	protoheme IX farnesyltransferase activity
AZK53_RS06640	COG3336	cytochrome c oxidase
AZK53_RS06650	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
AZK53_RS06655	COG2340	Cysteine-rich secretory protein family
AZK53_RS06665	COG2738	Putative neutral zinc metallopeptidase
AZK53_RS06670	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AZK53_RS06675	COG1694	Mazg nucleotide pyrophosphohydrolase
AZK53_RS06680	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AZK53_RS06685	COG1803	Methylglyoxal synthase
AZK53_RS06690	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AZK53_RS06695	COG0438	transferase activity, transferring glycosyl groups
AZK53_RS06700	COG0617	tRNA 3'-terminal CCA addition
AZK53_RS06705	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AZK53_RS06705	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AZK53_RS06715	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AZK53_RS06720	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AZK53_RS06725	COG1199	ATP-dependent helicase activity
AZK53_RS06725	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AZK53_RS06740	COG0436	Aminotransferase
AZK53_RS06745	COG0017	Asparaginyl-tRNA synthetase
AZK53_RS06750	COG3935	DnaD domain protein
AZK53_RS06755	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AZK53_RS06765	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AZK53_RS06765	COG4499	WXG100 protein secretion system (Wss), protein YukC
AZK53_RS06770	COG3331	DNA recombination
AZK53_RS06805	COG5337	Spore coat protein CotH
AZK53_RS06820	COG0626	cystathionine gamma-synthase activity
AZK53_RS06825	COG0626	cystathionine gamma-synthase activity
AZK53_RS06840	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AZK53_RS06860	COG3706	GGDEF domain
AZK53_RS06870	COG1111	helicase
AZK53_RS06870	COG1205	dead DEAH box helicase
AZK53_RS06875	COG3359	exonuclease
AZK53_RS06885	COG4474	Belongs to the UPF0398 family
AZK53_RS06890	COG3599	regulation of cell shape
AZK53_RS06920	COG2197	response regulator
AZK53_RS06925	COG0366	Alpha amylase catalytic
AZK53_RS06930	COG0116	Belongs to the methyltransferase superfamily
AZK53_RS06945	COG1175	transmembrane transport
AZK53_RS06955	COG3842	ATPase activity
AZK53_RS06965	COG1199	ATP-dependent helicase activity
AZK53_RS06970	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AZK53_RS06975	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AZK53_RS06980	COG2233	PERMEase
AZK53_RS06985	COG0583	DNA-binding transcription factor activity
AZK53_RS06990	COG1012	belongs to the aldehyde dehydrogenase family
AZK53_RS07000	COG3424	synthase
AZK53_RS07005	COG1755	Isoprenylcysteine carboxyl methyltransferase
AZK53_RS07010	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AZK53_RS07015	COG3541	Predicted nucleotidyltransferase
AZK53_RS07040	COG0328	RNA-DNA hybrid ribonuclease activity
AZK53_RS07045	COG0328	RNA-DNA hybrid ribonuclease activity
AZK53_RS07070	COG2814	Major facilitator Superfamily
AZK53_RS07080	COG2233	PERMEase
AZK53_RS07085	COG2362	D-Aminopeptidase
AZK53_RS07090	COG0601	transmembrane transport
AZK53_RS07095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZK53_RS07100	COG0444	Belongs to the ABC transporter superfamily
AZK53_RS07105	COG4166	transmembrane transport
AZK53_RS07110	COG1619	proteins homologs of microcin C7 resistance protein MccF
AZK53_RS07115	COG0791	NLP P60 protein
AZK53_RS07120	COG4608	Belongs to the ABC transporter superfamily
AZK53_RS07140	COG5001	Diguanylate cyclase
AZK53_RS07140	COG3300	MHYT domain
AZK53_RS07170	COG2197	response regulator
AZK53_RS07175	COG4585	Histidine kinase
AZK53_RS07180	COG3239	Fatty acid desaturase
AZK53_RS07185	COG2205	protein histidine kinase activity
AZK53_RS07195	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AZK53_RS07210	COG1388	LysM domain
AZK53_RS07210	COG0791	NLP P60 protein
AZK53_RS07215	COG1819	glycosyl
AZK53_RS07220	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AZK53_RS07235	COG2814	Major facilitator Superfamily
AZK53_RS07245	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_RS07250	COG3964	amidohydrolase
AZK53_RS07270	COG2188	Transcriptional regulator
AZK53_RS07280	COG0434	BtpA family
AZK53_RS07285	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AZK53_RS07295	COG1785	Belongs to the alkaline phosphatase family
AZK53_RS07300	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AZK53_RS07305	COG1404	Belongs to the peptidase S8 family
AZK53_RS07315	COG1846	Transcriptional regulator
AZK53_RS07320	COG1566	PFAM secretion protein HlyD family protein
AZK53_RS07325	COG2814	Major facilitator Superfamily
AZK53_RS07330	COG1846	Transcriptional regulator
AZK53_RS07340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AZK53_RS07345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AZK53_RS07350	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AZK53_RS07355	COG1120	ATPase activity
AZK53_RS07360	COG0492	ferredoxin-NADP+ reductase activity
AZK53_RS07370	COG2814	Major facilitator Superfamily
AZK53_RS07390	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AZK53_RS07395	COG1733	regulation of RNA biosynthetic process
AZK53_RS07400	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AZK53_RS07410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZK53_RS07420	COG3448	diguanylate cyclase activity
AZK53_RS07420	COG4175	Glycine betaine
AZK53_RS07425	COG4176	ABC-type proline glycine betaine transport system permease component
AZK53_RS07440	COG0784	Response regulator, receiver
AZK53_RS07440	COG2205	protein histidine kinase activity
AZK53_RS07445	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AZK53_RS07450	COG2208	phosphoserine phosphatase activity
AZK53_RS07460	COG0531	amino acid
AZK53_RS07470	COG1011	Hydrolase
AZK53_RS07475	COG0405	Gamma-glutamyltransferase
AZK53_RS07480	COG1621	beta-fructofuranosidase activity
AZK53_RS07485	COG1621	beta-fructofuranosidase activity
AZK53_RS07490	COG2193	ferroxidase activity
AZK53_RS07495	COG0477	Major facilitator Superfamily
AZK53_RS07500	COG0156	8-amino-7-oxononanoate synthase activity
AZK53_RS07505	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AZK53_RS07515	COG2814	Major facilitator Superfamily
AZK53_RS07530	COG1012	belongs to the aldehyde dehydrogenase family
AZK53_RS07535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZK53_RS07545	COG1280	lysine exporter protein (LysE YggA)
AZK53_RS07550	COG1113	amino acid transport
AZK53_RS07555	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AZK53_RS07575	COG1113	amino acid transport
AZK53_RS07595	COG1609	Transcriptional regulator
AZK53_RS07600	COG2223	nitrite transmembrane transporter activity
AZK53_RS07610	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AZK53_RS07615	COG1621	beta-fructofuranosidase activity
AZK53_RS07620	COG3933	PFAM sigma-54 factor interaction domain-containing protein
AZK53_RS07620	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AZK53_RS07625	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AZK53_RS07630	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AZK53_RS07635	COG3715	PTS system
AZK53_RS07640	COG3716	PTS system mannose fructose sorbose family IID component
AZK53_RS07645	COG1621	beta-fructofuranosidase activity
AZK53_RS07650	COG0765	amino acid transport
AZK53_RS07655	COG0765	amino acid transport
AZK53_RS07660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZK53_RS07665	COG1464	Belongs to the NlpA lipoprotein family
AZK53_RS07670	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AZK53_RS07675	COG2011	ABC-type metal ion transport system permease component
AZK53_RS07695	COG1464	Belongs to the NlpA lipoprotein family
AZK53_RS07700	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AZK53_RS07705	COG2011	ABC-type metal ion transport system permease component
AZK53_RS07710	COG1464	Belongs to the NlpA lipoprotein family
AZK53_RS07715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZK53_RS07720	COG0024	Methionine aminopeptidase
AZK53_RS07730	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AZK53_RS07740	COG0656	L-ascorbic acid biosynthetic process
AZK53_RS07745	COG2986	histidine ammonia-lyase
AZK53_RS07755	COG1228	amidohydrolase
AZK53_RS07760	COG0010	Belongs to the arginase family
AZK53_RS07765	COG1846	Transcriptional regulator
AZK53_RS07775	COG0473	3-isopropylmalate dehydrogenase activity
AZK53_RS07780	COG1288	antiporter activity
AZK53_RS07785	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AZK53_RS07815	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AZK53_RS07835	COG2364	Membrane
AZK53_RS07840	COG1846	Transcriptional regulator
AZK53_RS07845	COG0456	acetyltransferase
AZK53_RS07875	COG0574	Belongs to the PEP-utilizing enzyme family
AZK53_RS07875	COG3848	Pyruvate phosphate dikinase
AZK53_RS07880	COG1309	transcriptional regulator
AZK53_RS07885	COG2814	Major facilitator Superfamily
AZK53_RS07890	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AZK53_RS07895	COG3958	Transketolase
AZK53_RS07900	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_RS07905	COG2186	Transcriptional regulator
AZK53_RS07915	COG0205	6-phosphofructokinase activity
AZK53_RS07920	COG0698	ribose 5-phosphate isomerase
AZK53_RS07945	COG0791	NLP P60 protein
AZK53_RS07945	COG1388	LysM domain
AZK53_RS07950	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AZK53_RS07965	COG2318	DinB family
AZK53_RS07990	COG0583	DNA-binding transcription factor activity
AZK53_RS07995	COG0596	Alpha beta hydrolase
AZK53_RS08020	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_RS08035	COG5002	protein histidine kinase activity
AZK53_RS08035	COG3850	Histidine kinase
AZK53_RS08040	COG0745	RESPONSE REGULATOR receiver
AZK53_RS08045	COG0586	Pfam SNARE associated Golgi protein
AZK53_RS08065	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AZK53_RS08075	COG0697	spore germination
AZK53_RS08105	COG0387	Pfam Sodium calcium exchanger
AZK53_RS08110	COG0318	PFAM AMP-dependent synthetase and ligase
AZK53_RS08125	COG1309	transcriptional regulator
AZK53_RS08130	COG0861	Integral membrane protein TerC family
AZK53_RS08140	COG5577	PFAM Coat F domain
AZK53_RS08155	COG1366	Belongs to the anti-sigma-factor antagonist family
AZK53_RS08165	COG1522	sequence-specific DNA binding
AZK53_RS08185	COG2076	Multidrug Resistance protein
AZK53_RS08200	COG1278	Cold shock
AZK53_RS08210	COG0513	Belongs to the DEAD box helicase family
AZK53_RS08215	COG1278	Cold shock
AZK53_RS08230	COG0028	Belongs to the TPP enzyme family
AZK53_RS08265	COG2172	sigma factor antagonist activity
AZK53_RS08270	COG1388	LysM domain
AZK53_RS08270	COG3858	chitin binding
AZK53_RS08275	COG1376	ErfK ybiS ycfS ynhG family protein
AZK53_RS08280	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AZK53_RS08300	COG2226	methyltransferase
AZK53_RS08310	COG1733	regulation of RNA biosynthetic process
AZK53_RS08315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZK53_RS08330	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AZK53_RS08335	COG3420	alginic acid biosynthetic process
AZK53_RS08355	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AZK53_RS08360	COG0640	Transcriptional regulator
AZK53_RS08370	COG0640	Transcriptional regulator
AZK53_RS08375	COG0346	lactoylglutathione lyase activity
AZK53_RS08380	COG0589	response to stress
AZK53_RS08380	COG0475	glutathione-regulated potassium exporter activity
AZK53_RS08390	COG2076	Multidrug Resistance protein
AZK53_RS08395	COG2076	Multidrug Resistance protein
AZK53_RS08425	COG0488	(ABC) transporter
AZK53_RS08445	COG0583	DNA-binding transcription factor activity
AZK53_RS08450	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AZK53_RS08460	COG0753	catalase activity
AZK53_RS08475	COG1366	Belongs to the anti-sigma-factor antagonist family
AZK53_RS08480	COG1366	Belongs to the anti-sigma-factor antagonist family
AZK53_RS08500	COG0384	phenazine biosynthesis protein PhzF
AZK53_RS08510	COG5577	PFAM Coat F domain
AZK53_RS08520	COG1063	alcohol dehydrogenase
AZK53_RS08525	COG5577	PFAM Coat F domain
AZK53_RS08535	COG2814	Major facilitator Superfamily
AZK53_RS08545	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_RS08560	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AZK53_RS08570	COG0789	Transcriptional regulator
AZK53_RS08575	COG1278	Cold shock
AZK53_RS08615	COG1113	amino acid transport
AZK53_RS08625	COG2207	Transcriptional regulator
AZK53_RS08635	COG2376	Dihydroxyacetone kinase
AZK53_RS08655	COG0745	RESPONSE REGULATOR receiver
AZK53_RS08660	COG0745	RESPONSE REGULATOR receiver
AZK53_RS08665	COG5002	protein histidine kinase activity
AZK53_RS08670	COG0671	phosphoesterase, PA-phosphatase related
AZK53_RS08680	COG2851	Citrate transporter
AZK53_RS08730	COG2318	DinB family
AZK53_RS08735	COG2890	protein-(glutamine-N5) methyltransferase activity
AZK53_RS08770	COG2311	Membrane
AZK53_RS08805	COG1114	Component of the transport system for branched-chain amino acids
AZK53_RS08815	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AZK53_RS08825	COG4282	regulation of fungal-type cell wall biogenesis
AZK53_RS08850	COG0574	Belongs to the PEP-utilizing enzyme family
AZK53_RS08850	COG3848	Pyruvate phosphate dikinase
AZK53_RS08855	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AZK53_RS08865	COG0601	transmembrane transport
AZK53_RS08870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZK53_RS08875	COG0444	Belongs to the ABC transporter superfamily
AZK53_RS08880	COG4608	Belongs to the ABC transporter superfamily
AZK53_RS08885	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AZK53_RS08890	COG0477	Major facilitator Superfamily
AZK53_RS08905	COG1012	belongs to the aldehyde dehydrogenase family
AZK53_RS08940	COG0517	IMP dehydrogenase activity
AZK53_RS08960	COG1309	transcriptional regulator
AZK53_RS08970	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AZK53_RS08975	COG1845	cytochrome c oxidase, subunit III
AZK53_RS08985	COG0589	response to stress
AZK53_RS08990	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_RS08995	COG1612	heme a metabolic process
AZK53_RS09000	COG2072	flavoprotein involved in K transport
AZK53_RS09010	COG2252	PERMEase
AZK53_RS09020	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AZK53_RS09025	COG0022	dehydrogenase e1 component
AZK53_RS09030	COG0508	dehydrogenase complex catalyzes the overall conversion of
AZK53_RS09035	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AZK53_RS09040	COG3284	Transcriptional regulator
AZK53_RS09045	COG1063	alcohol dehydrogenase
AZK53_RS09055	COG1846	Transcriptional regulator
AZK53_RS09075	COG0628	permease
AZK53_RS09080	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AZK53_RS09090	COG2211	Major facilitator Superfamily
AZK53_RS09115	COG0589	response to stress
AZK53_RS09120	COG5002	protein histidine kinase activity
AZK53_RS09130	COG1937	Protein conserved in bacteria
AZK53_RS09135	COG2608	mercury ion transmembrane transporter activity
AZK53_RS09140	COG2217	Heavy metal translocating P-type atpase
AZK53_RS09150	COG1388	LysM domain
AZK53_RS09155	COG2271	Major facilitator Superfamily
AZK53_RS09185	COG0640	Transcriptional regulator
AZK53_RS09190	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AZK53_RS09195	COG0551	DNA topoisomerase type I activity
AZK53_RS09195	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AZK53_RS09200	COG5444	nuclease activity
AZK53_RS09210	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AZK53_RS09220	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AZK53_RS09225	COG2323	membrane
AZK53_RS09240	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AZK53_RS09245	COG1802	Transcriptional regulator
AZK53_RS09250	COG0473	3-isopropylmalate dehydrogenase activity
AZK53_RS09255	COG2814	Major facilitator Superfamily
AZK53_RS09260	COG1733	regulation of RNA biosynthetic process
AZK53_RS09265	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AZK53_RS09265	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AZK53_RS09270	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AZK53_RS09270	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AZK53_RS09290	COG5566	PFAM Mor transcription activator
AZK53_RS09305	COG0561	phosphatase activity
AZK53_RS09310	COG1876	peptidase activity
AZK53_RS09350	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AZK53_RS09365	COG0386	Belongs to the glutathione peroxidase family
AZK53_RS09370	COG1418	mRNA catabolic process
AZK53_RS09375	COG0488	(ABC) transporter
AZK53_RS09380	COG1413	lyase activity
AZK53_RS09385	COG0726	polysaccharide deacetylase
AZK53_RS09395	COG2136	Putative SAM-dependent methyltransferase
AZK53_RS09395	COG2521	methyltransferase
AZK53_RS09405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AZK53_RS09410	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AZK53_RS09420	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AZK53_RS09425	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AZK53_RS09430	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
AZK53_RS09435	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AZK53_RS09440	COG0406	alpha-ribazole phosphatase activity
AZK53_RS09450	COG2096	Adenosyltransferase
AZK53_RS09455	COG2962	Rard protein
AZK53_RS09465	COG0523	cobalamin synthesis protein
AZK53_RS09470	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AZK53_RS09475	COG0322	excinuclease ABC activity
AZK53_RS09485	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AZK53_RS09490	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AZK53_RS09495	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AZK53_RS09505	COG3011	Protein conserved in bacteria
AZK53_RS09510	COG1595	DNA-templated transcription, initiation
AZK53_RS09530	COG2002	toxin-antitoxin pair type II binding
AZK53_RS09535	COG0534	Mate efflux family protein
AZK53_RS09540	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_RS09565	COG1368	sulfuric ester hydrolase activity
AZK53_RS09575	COG3853	Toxic anion resistance protein (TelA)
AZK53_RS09600	COG2234	aminopeptidase activity
AZK53_RS09605	COG5002	protein histidine kinase activity
AZK53_RS09615	COG1823	symporter activity
AZK53_RS09620	COG1523	belongs to the glycosyl hydrolase 13 family
AZK53_RS09625	COG1012	belongs to the aldehyde dehydrogenase family
AZK53_RS09630	COG2124	cytochrome p450
AZK53_RS09630	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AZK53_RS09635	COG2112	serine threonine protein kinase
AZK53_RS09645	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AZK53_RS09650	COG1360	Flagellar Motor Protein
AZK53_RS09665	COG3361	conserved protein (COG2071)
AZK53_RS09670	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AZK53_RS09675	COG1757	Na H antiporter
AZK53_RS09685	COG0833	amino acid
AZK53_RS09690	COG3594	Acyltransferase
AZK53_RS09695	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AZK53_RS09700	COG0745	RESPONSE REGULATOR receiver
AZK53_RS09705	COG5002	protein histidine kinase activity
AZK53_RS09710	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AZK53_RS09715	COG3104	oligopeptide transport
AZK53_RS09725	COG0281	malic enzyme
AZK53_RS09730	COG3493	citrate carrier protein
AZK53_RS09735	COG0561	phosphatase activity
AZK53_RS09740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZK53_RS09750	COG0456	acetyltransferase
AZK53_RS09755	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AZK53_RS09760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZK53_RS09765	COG0765	amino acid transport
AZK53_RS09770	COG0765	amino acid transport
AZK53_RS09775	COG1126	abc transporter atp-binding protein
AZK53_RS09780	COG0196	riboflavin kinase activity
AZK53_RS09785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZK53_RS09795	COG0860	N-Acetylmuramoyl-L-alanine amidase
AZK53_RS09835	COG1611	Belongs to the LOG family
AZK53_RS09840	COG0281	malic enzyme
AZK53_RS09845	COG3402	PFAM membrane-flanked domain
AZK53_RS09850	COG3428	Bacterial PH domain
AZK53_RS09865	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AZK53_RS09870	COG0109	protoheme IX farnesyltransferase activity
AZK53_RS09875	COG4195	phage-related replication protein
AZK53_RS09885	COG0789	Transcriptional regulator
AZK53_RS09915	COG0583	DNA-binding transcription factor activity
AZK53_RS09920	COG0069	glutamate synthase activity
AZK53_RS09920	COG0070	glutamate synthase
AZK53_RS09920	COG0067	glutamate synthase
AZK53_RS09925	COG0493	'glutamate synthase
AZK53_RS09945	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AZK53_RS09960	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AZK53_RS09970	COG1846	Transcriptional regulator
AZK53_RS09975	COG1380	Effector of murein hydrolase LrgA
AZK53_RS09980	COG1346	cytolysis
AZK53_RS09985	COG1366	Belongs to the anti-sigma-factor antagonist family
AZK53_RS10000	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AZK53_RS10005	COG0463	Glycosyl transferase, family 2
AZK53_RS10015	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AZK53_RS10020	COG0745	RESPONSE REGULATOR receiver
AZK53_RS10035	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AZK53_RS10045	COG4208	sulfate ABC transporter
AZK53_RS10060	COG0745	RESPONSE REGULATOR receiver
AZK53_RS10085	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AZK53_RS10095	COG1349	DNA-binding transcription factor activity
AZK53_RS10100	COG1105	Belongs to the carbohydrate kinase PfkB family
AZK53_RS10105	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AZK53_RS10105	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AZK53_RS10105	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AZK53_RS10110	COG0527	aspartate kinase activity
AZK53_RS10120	COG2032	superoxide dismutase activity
AZK53_RS10135	COG0300	oxidoreductase activity
AZK53_RS10140	COG0640	Transcriptional regulator
AZK53_RS10145	COG1012	belongs to the aldehyde dehydrogenase family
AZK53_RS10150	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AZK53_RS10165	COG0733	neurotransmitter:sodium symporter activity
AZK53_RS10170	COG3773	Cell wall hydrolase
AZK53_RS10190	COG0673	inositol 2-dehydrogenase activity
AZK53_RS10195	COG1082	Xylose isomerase domain protein TIM barrel
AZK53_RS10200	COG2094	Belongs to the DNA glycosylase MPG family
AZK53_RS10205	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AZK53_RS10215	COG0454	-acetyltransferase
AZK53_RS10225	COG2814	Major facilitator Superfamily
AZK53_RS10240	COG3871	stress protein (general stress protein 26)
AZK53_RS10265	COG1595	DNA-templated transcription, initiation
AZK53_RS10270	COG4873	Protein conserved in bacteria
AZK53_RS10275	COG0714	Associated with various cellular activities
AZK53_RS10280	COG4548	von Willebrand factor, type A
AZK53_RS10285	COG0697	spore germination
AZK53_RS10295	COG2207	Transcriptional regulator
AZK53_RS10300	COG1994	Peptidase M50
AZK53_RS10305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AZK53_RS10310	COG1119	ATPase activity
AZK53_RS10325	COG1657	PFAM Prenyltransferase squalene oxidase
AZK53_RS10335	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AZK53_RS10335	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AZK53_RS10345	COG0384	phenazine biosynthesis protein PhzF
AZK53_RS10360	COG1378	Sugar-specific transcriptional regulator TrmB
AZK53_RS10365	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AZK53_RS10370	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_RS10390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZK53_RS10395	COG1279	arginine transmembrane transporter activity
AZK53_RS10420	COG1396	sequence-specific DNA binding
AZK53_RS10435	COG0494	nUDIX hydrolase
AZK53_RS10440	COG1335	isochorismatase
AZK53_RS10445	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AZK53_RS10450	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AZK53_RS10455	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AZK53_RS10460	COG1098	S1 RNA binding domain
AZK53_RS10465	COG1404	Belongs to the peptidase S8 family
AZK53_RS10470	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_RS10475	COG1254	Belongs to the acylphosphatase family
AZK53_RS10480	COG2223	nitrite transmembrane transporter activity
AZK53_RS10485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZK53_RS10495	COG2207	Transcriptional regulator
AZK53_RS10495	COG0662	Cupin 2, conserved barrel domain protein
AZK53_RS10500	COG0697	spore germination
AZK53_RS10505	COG0488	(ABC) transporter
AZK53_RS10510	COG0697	spore germination
AZK53_RS10515	COG0531	amino acid
AZK53_RS10530	COG1131	(ABC) transporter
AZK53_RS10535	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AZK53_RS10540	COG1757	Na H antiporter
AZK53_RS10545	COG1609	Transcriptional regulator
AZK53_RS10555	COG1533	DNA photolyase activity
AZK53_RS10575	COG0551	DNA topoisomerase type I activity
AZK53_RS10575	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AZK53_RS10585	COG0446	pyridine nucleotide-disulphide oxidoreductase
AZK53_RS10615	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AZK53_RS10635	COG1757	Na H antiporter
AZK53_RS10660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AZK53_RS10665	COG2720	vancomycin resistance protein
AZK53_RS10705	COG0514	ATP-dependent DNA helicase (RecQ)
AZK53_RS10720	COG1012	belongs to the aldehyde dehydrogenase family
AZK53_RS10735	COG1575	Belongs to the MenA family. Type 1 subfamily
AZK53_RS10740	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AZK53_RS10755	COG2814	Major facilitator Superfamily
AZK53_RS10760	COG0583	DNA-binding transcription factor activity
AZK53_RS10765	COG1725	Transcriptional regulator
AZK53_RS10770	COG1131	(ABC) transporter
AZK53_RS10780	COG1595	DNA-templated transcription, initiation
AZK53_RS10795	COG1764	response to oxidative stress
AZK53_RS10800	COG1846	Transcriptional regulator
AZK53_RS10815	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
AZK53_RS10825	COG3584	3D domain protein
AZK53_RS10825	COG1388	LysM domain
AZK53_RS10845	COG5002	protein histidine kinase activity
AZK53_RS10850	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AZK53_RS10855	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AZK53_RS10860	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AZK53_RS10875	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AZK53_RS10890	COG2409	Drug exporters of the RND superfamily
AZK53_RS10895	COG1834	amidinotransferase
AZK53_RS10905	COG1295	ribonuclease BN
AZK53_RS10985	COG0110	maltose O-acetyltransferase activity
AZK53_RS10990	COG0346	lactoylglutathione lyase activity
AZK53_RS11000	COG1366	Belongs to the anti-sigma-factor antagonist family
AZK53_RS11010	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AZK53_RS11015	COG2176	DNA-directed DNA polymerase activity
AZK53_RS11030	COG0114	fumarate hydratase activity
AZK53_RS11040	COG3409	Peptidoglycan-binding domain 1 protein
AZK53_RS11040	COG3757	hydrolase, family 25
AZK53_RS11050	COG5002	protein histidine kinase activity
AZK53_RS11085	COG0778	Nitroreductase
AZK53_RS11095	COG0300	oxidoreductase activity
AZK53_RS11100	COG3290	protein histidine kinase activity
AZK53_RS11105	COG4565	transcriptional regulatory protein
AZK53_RS11110	COG2851	Citrate transporter
AZK53_RS11120	COG2610	gluconate transmembrane transporter activity
AZK53_RS11125	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_RS11130	COG2195	Cleaves the N-terminal amino acid of tripeptides
AZK53_RS11155	COG4122	O-methyltransferase activity
AZK53_RS11160	COG0583	DNA-binding transcription factor activity
AZK53_RS11170	COG1301	dicarboxylic acid transport
AZK53_RS11175	COG0019	diaminopimelate decarboxylase activity
AZK53_RS11185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZK53_RS11195	COG4191	Histidine kinase
AZK53_RS11205	COG1960	acyl-CoA dehydrogenase activity
AZK53_RS11210	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_RS11215	COG0318	PFAM AMP-dependent synthetase and ligase
AZK53_RS11225	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZK53_RS11230	COG1024	Enoyl-CoA hydratase
AZK53_RS11245	COG2045	Belongs to the ComB family
AZK53_RS11250	COG1960	acyl-CoA dehydrogenase activity
AZK53_RS11255	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_RS11260	COG1024	Enoyl-CoA hydratase
AZK53_RS11275	COG1141	Ferredoxin
AZK53_RS11285	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AZK53_RS11295	COG0183	Belongs to the thiolase family
AZK53_RS11300	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AZK53_RS11305	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AZK53_RS11325	COG1509	lysine 2,3-aminomutase activity
AZK53_RS11335	COG0833	amino acid
AZK53_RS11340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZK53_RS11355	COG1979	alcohol dehydrogenase
AZK53_RS11360	COG0738	Major facilitator superfamily
AZK53_RS11365	COG1181	Belongs to the D-alanine--D-alanine ligase family
AZK53_RS11385	COG3977	Valine--pyruvate aminotransferase
AZK53_RS11390	COG3773	Cell wall hydrolase
AZK53_RS11400	COG3119	arylsulfatase activity
AZK53_RS11405	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AZK53_RS11415	COG0531	amino acid
AZK53_RS11425	COG1846	Transcriptional regulator
AZK53_RS11430	COG1033	growth of symbiont in host cell
AZK53_RS11430	COG2409	Drug exporters of the RND superfamily
AZK53_RS11435	COG1366	Belongs to the anti-sigma-factor antagonist family
AZK53_RS11435	COG2202	Pas domain
AZK53_RS11440	COG3832	glyoxalase III activity
AZK53_RS11445	COG0640	Transcriptional regulator
AZK53_RS11455	COG2267	carboxylic ester hydrolase activity
AZK53_RS11465	COG3386	PFAM SMP-30 Gluconolaconase
AZK53_RS11475	COG2368	4-hydroxyphenylacetate
AZK53_RS11480	COG3739	integral membrane protein
AZK53_RS11490	COG0326	Molecular chaperone. Has ATPase activity
AZK53_RS11495	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AZK53_RS11515	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AZK53_RS11520	COG3757	hydrolase, family 25
AZK53_RS11520	COG3409	Peptidoglycan-binding domain 1 protein
AZK53_RS11530	COG0697	spore germination
AZK53_RS11535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZK53_RS11550	COG4572	Cation transport regulator
AZK53_RS11555	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AZK53_RS11560	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AZK53_RS11660	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AZK53_RS11675	COG0494	nUDIX hydrolase
AZK53_RS11680	COG0702	epimerase
AZK53_RS11685	COG0318	PFAM AMP-dependent synthetase and ligase
AZK53_RS11690	COG1846	Transcriptional regulator
AZK53_RS11695	COG2720	vancomycin resistance protein
AZK53_RS11700	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AZK53_RS11725	COG0076	glutamate decarboxylase activity
AZK53_RS11750	COG2116	formate transmembrane transporter activity
AZK53_RS11755	COG5609	conserved protein (DUF2294)
AZK53_RS11770	COG2271	Major facilitator Superfamily
AZK53_RS11775	COG0277	FAD linked oxidase domain protein
AZK53_RS11780	COG0840	transmembrane signaling receptor activity
AZK53_RS11790	COG0622	Phosphoesterase
AZK53_RS11800	COG1408	metallophosphoesterase
AZK53_RS11805	COG3663	DNA glycosylase
AZK53_RS11810	COG0791	NLP P60 protein
AZK53_RS11810	COG3883	PFAM NLP P60 protein
AZK53_RS11815	COG1587	Uroporphyrinogen-III synthase
AZK53_RS11820	COG1414	Transcriptional regulator
AZK53_RS11825	COG0439	Biotin carboxylase
AZK53_RS11830	COG0511	ligase activity, forming carbon-carbon bonds
AZK53_RS11835	COG1984	allophanate hydrolase subunit 2
AZK53_RS11840	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AZK53_RS11845	COG4336	lyase activity
AZK53_RS11850	COG1914	H( )-stimulated, divalent metal cation uptake system
AZK53_RS11855	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AZK53_RS11870	COG0318	PFAM AMP-dependent synthetase and ligase
AZK53_RS11875	COG1268	BioY protein
AZK53_RS11880	COG0183	Belongs to the thiolase family
AZK53_RS11900	COG0431	NADPH-dependent FMN reductase
AZK53_RS11905	COG2197	response regulator
AZK53_RS11910	COG2203	Gaf domain
AZK53_RS11910	COG4585	Histidine kinase
AZK53_RS11930	COG0697	spore germination
AZK53_RS11940	COG2153	protein acetylation
AZK53_RS11945	COG0129	dihydroxy-acid dehydratase activity
AZK53_RS11950	COG2267	carboxylic ester hydrolase activity
AZK53_RS11955	COG1227	inorganic diphosphatase activity
AZK53_RS11975	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AZK53_RS11985	COG0204	Acyl-transferase
AZK53_RS11990	COG2233	PERMEase
AZK53_RS11995	COG3195	allantoin biosynthetic process
AZK53_RS11995	COG3648	Uricase
AZK53_RS12020	COG1914	H( )-stimulated, divalent metal cation uptake system
AZK53_RS12035	COG1011	Hydrolase
AZK53_RS12040	COG1846	Transcriptional regulator
AZK53_RS12050	COG4974	Belongs to the 'phage' integrase family
AZK53_RS12065	COG0531	amino acid
AZK53_RS12070	COG4302	ethanolamine ammonia-lyase activity
AZK53_RS12075	COG4303	Ethanolamine ammonia lyase large subunit
AZK53_RS12080	COG4819	ethanolamine utilization protein
AZK53_RS12090	COG0833	amino acid
AZK53_RS12100	COG1247	-acetyltransferase
AZK53_RS12105	COG1335	isochorismatase
AZK53_RS12115	COG3403	YqcI/YcgG family
AZK53_RS12120	COG1280	lysine exporter protein (LysE YggA)
AZK53_RS12125	COG2267	carboxylic ester hydrolase activity
AZK53_RS12130	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AZK53_RS12135	COG0187	DNA topoisomerase II activity
AZK53_RS12140	COG1832	CoA-binding protein
AZK53_RS12145	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AZK53_RS12150	COG4841	protein insertion into membrane
AZK53_RS12155	COG0824	Thioesterase
AZK53_RS12180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AZK53_RS12185	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AZK53_RS12205	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AZK53_RS12240	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AZK53_RS12245	COG2068	MobA-Related Protein
AZK53_RS12250	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AZK53_RS12305	COG1183	phosphatidylcholine synthase activity
AZK53_RS12320	COG2814	Major facilitator Superfamily
AZK53_RS12325	COG1683	Conserved Protein
AZK53_RS12330	COG1302	Protein conserved in bacteria
AZK53_RS12345	COG1295	ribonuclease BN
AZK53_RS12355	COG1115	amino acid carrier protein
AZK53_RS12360	COG2814	Major facilitator Superfamily
AZK53_RS12370	COG2814	Major facilitator Superfamily
AZK53_RS12375	COG0789	Transcriptional regulator
AZK53_RS12385	COG0288	reversible hydration of carbon dioxide
AZK53_RS12390	COG0659	secondary active sulfate transmembrane transporter activity
AZK53_RS12395	COG0745	RESPONSE REGULATOR receiver
AZK53_RS12400	COG5002	protein histidine kinase activity
AZK53_RS12410	COG0477	Major facilitator Superfamily
AZK53_RS12415	COG4282	regulation of fungal-type cell wall biogenesis
AZK53_RS12420	COG0531	amino acid
AZK53_RS12430	COG0860	N-Acetylmuramoyl-L-alanine amidase
AZK53_RS12435	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
AZK53_RS12505	COG1363	Peptidase, m42
AZK53_RS12515	COG1114	Component of the transport system for branched-chain amino acids
AZK53_RS12535	COG0004	ammonium transporteR
AZK53_RS12550	COG1252	NADH dehydrogenase
AZK53_RS12555	COG0679	Auxin Efflux Carrier
AZK53_RS12560	COG0281	malic enzyme
AZK53_RS12565	COG1473	amidohydrolase
AZK53_RS12570	COG2271	Major facilitator Superfamily
AZK53_RS12590	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AZK53_RS12595	COG0163	prenyltransferase activity
AZK53_RS12600	COG0583	DNA-binding transcription factor activity
AZK53_RS12605	COG0679	Auxin Efflux Carrier
AZK53_RS12625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZK53_RS12630	COG0247	lactate metabolic process
AZK53_RS12635	COG0277	FAD linked oxidase domain protein
AZK53_RS12640	COG3835	regulator
AZK53_RS12645	COG0693	protein deglycase activity
AZK53_RS12655	COG2610	gluconate transmembrane transporter activity
AZK53_RS12675	COG1131	(ABC) transporter
AZK53_RS12685	COG2197	response regulator
AZK53_RS12720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZK53_RS12730	COG0586	Pfam SNARE associated Golgi protein
AZK53_RS12735	COG1515	deoxyribonuclease V activity
AZK53_RS12740	COG0584	glycerophosphoryl diester phosphodiesterase
AZK53_RS12745	COG3153	acetyltransferase
AZK53_RS12745	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AZK53_RS12755	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AZK53_RS12760	COG0531	amino acid
AZK53_RS12795	COG2849	repeat protein
AZK53_RS12800	COG5444	nuclease activity
AZK53_RS12815	COG0534	Mate efflux family protein
AZK53_RS12820	COG1566	PFAM secretion protein HlyD family protein
AZK53_RS12830	COG1846	Transcriptional regulator
AZK53_RS12835	COG0708	Exodeoxyribonuclease III
AZK53_RS12850	COG0673	inositol 2-dehydrogenase activity
AZK53_RS12855	COG1349	DNA-binding transcription factor activity
AZK53_RS12860	COG3853	Toxic anion resistance protein (TelA)
AZK53_RS12870	COG2310	stress, protein
AZK53_RS12875	COG2310	stress, protein
AZK53_RS12880	COG2310	stress, protein
AZK53_RS12885	COG0737	Belongs to the 5'-nucleotidase family
AZK53_RS12900	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AZK53_RS12905	COG1131	(ABC) transporter
AZK53_RS12915	COG2084	Dehydrogenase
AZK53_RS12920	COG1278	Cold shock
AZK53_RS12925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZK53_RS12930	COG0028	Belongs to the TPP enzyme family
AZK53_RS12935	COG1278	Cold shock
AZK53_RS12965	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_RS12975	COG0427	acetyl-CoA hydrolase
AZK53_RS12980	COG3279	Response regulator of the LytR AlgR family
AZK53_RS12985	COG2323	membrane
AZK53_RS12990	COG2814	Major facilitator Superfamily
AZK53_RS12995	COG1388	LysM domain
AZK53_RS12995	COG3584	3D domain protein
AZK53_RS13000	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AZK53_RS13025	COG3340	Belongs to the peptidase S51 family
AZK53_RS13120	COG2318	DinB family
AZK53_RS13130	COG0579	oxidoreductase
AZK53_RS13160	COG0488	(ABC) transporter
AZK53_RS13165	COG1486	melibiose metabolic process
AZK53_RS13170	COG0395	ABC-type sugar transport system, permease component
AZK53_RS13175	COG1175	transmembrane transport
AZK53_RS13180	COG1653	transport
AZK53_RS13185	COG1609	Transcriptional regulator
AZK53_RS13215	COG0596	Alpha beta hydrolase
AZK53_RS13220	COG1929	Belongs to the glycerate kinase type-1 family
AZK53_RS13225	COG2610	gluconate transmembrane transporter activity
AZK53_RS13230	COG3835	regulator
AZK53_RS13235	COG1454	alcohol dehydrogenase
AZK53_RS13240	COG3152	Membrane
AZK53_RS13255	COG0492	ferredoxin-NADP+ reductase activity
AZK53_RS13265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZK53_RS13270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZK53_RS13295	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AZK53_RS13305	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AZK53_RS13320	COG2390	Transcriptional regulator
AZK53_RS13350	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AZK53_RS13355	COG0501	Belongs to the peptidase M48B family
AZK53_RS13360	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZK53_RS13365	COG1742	UPF0060 membrane protein
AZK53_RS13370	COG2182	Extracellular solute-binding protein
AZK53_RS13390	COG2031	fatty acid transporter
AZK53_RS13420	COG2391	methyltransferase activity
AZK53_RS13435	COG1979	alcohol dehydrogenase
AZK53_RS13440	COG0583	DNA-binding transcription factor activity
AZK53_RS13450	COG0456	acetyltransferase
AZK53_RS13480	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_RS13485	COG1063	alcohol dehydrogenase
AZK53_RS13510	COG0025	NhaP-type Na H and K H
AZK53_RS13515	COG1253	flavin adenine dinucleotide binding
AZK53_RS13540	COG4608	Belongs to the ABC transporter superfamily
AZK53_RS13550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZK53_RS13555	COG0601	transmembrane transport
AZK53_RS13560	COG0747	negative chemotaxis
AZK53_RS13570	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AZK53_RS13585	COG1525	nuclease
AZK53_RS13595	COG0579	oxidoreductase
AZK53_RS13600	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AZK53_RS13605	COG0561	phosphatase activity
AZK53_RS13620	COG0668	transmembrane transport
AZK53_RS13645	COG2309	aminopeptidase activity
AZK53_RS13650	COG1414	Transcriptional regulator
AZK53_RS13660	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AZK53_RS13665	COG0277	FAD linked oxidase domain protein
AZK53_RS13670	COG0247	lactate metabolic process
AZK53_RS13675	COG0277	FAD linked oxidase domain protein
AZK53_RS13680	COG1620	l-lactate permease
AZK53_RS13700	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AZK53_RS13725	COG1595	DNA-templated transcription, initiation
AZK53_RS13745	COG4682	membrane
AZK53_RS13760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZK53_RS13765	COG1366	Belongs to the anti-sigma-factor antagonist family
AZK53_RS13770	COG0598	Magnesium transport protein CorA
AZK53_RS13775	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AZK53_RS13785	COG2323	membrane
AZK53_RS13790	COG1876	peptidase activity
AZK53_RS13805	COG5002	protein histidine kinase activity
AZK53_RS13810	COG0745	RESPONSE REGULATOR receiver
AZK53_RS13830	COG0508	dehydrogenase complex catalyzes the overall conversion of
AZK53_RS13835	COG0567	Dehydrogenase, E1 component
AZK53_RS13845	COG2814	Major facilitator Superfamily
AZK53_RS13850	COG1764	response to oxidative stress
AZK53_RS13860	COG2311	Membrane
AZK53_RS13920	COG0347	Belongs to the P(II) protein family
AZK53_RS13925	COG0004	ammonium transporteR
AZK53_RS13930	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AZK53_RS13945	COG0596	Alpha beta hydrolase
AZK53_RS13955	COG0456	acetyltransferase
AZK53_RS13955	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AZK53_RS13960	COG1960	acyl-CoA dehydrogenase activity
AZK53_RS14000	COG4604	ABC transporter, ATP-binding protein
AZK53_RS14005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AZK53_RS14010	COG1492	cobalamin metabolic process
AZK53_RS14020	COG0531	amino acid
AZK53_RS14030	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_RS14035	COG2404	hydrolase activity, acting on ester bonds
AZK53_RS14040	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AZK53_RS14050	COG1609	Transcriptional regulator
AZK53_RS14060	COG2271	Major facilitator Superfamily
AZK53_RS14065	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AZK53_RS14080	COG1233	COG1233 Phytoene dehydrogenase and related
AZK53_RS14085	COG0463	Glycosyl transferase, family 2
AZK53_RS14130	COG0804	urea catabolic process
AZK53_RS14140	COG0831	urea catabolic process
AZK53_RS14145	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AZK53_RS14150	COG0791	NLP P60 protein
AZK53_RS14150	COG1388	LysM domain
AZK53_RS14155	COG1388	LysM domain
AZK53_RS14155	COG3584	3D domain protein
AZK53_RS14160	COG0778	Nitroreductase
AZK53_RS14165	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AZK53_RS14170	COG0586	Pfam SNARE associated Golgi protein
AZK53_RS14180	COG0400	carboxylic ester hydrolase activity
AZK53_RS14185	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AZK53_RS14190	COG2244	polysaccharide biosynthetic process
AZK53_RS14195	COG0697	spore germination
AZK53_RS14200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZK53_RS14220	COG1132	(ABC) transporter
AZK53_RS14245	COG4195	phage-related replication protein
AZK53_RS14255	COG0783	Belongs to the Dps family
AZK53_RS14265	COG5577	PFAM Coat F domain
AZK53_RS14270	COG1253	flavin adenine dinucleotide binding
AZK53_RS14285	COG0517	IMP dehydrogenase activity
AZK53_RS14285	COG0516	GMP reductase activity
AZK53_RS14295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZK53_RS14295	COG0723	plastoquinol--plastocyanin reductase activity
AZK53_RS14310	COG0287	Prephenate dehydrogenase
AZK53_RS14320	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AZK53_RS14320	COG1605	Chorismate mutase
AZK53_RS14330	COG2059	Chromate
AZK53_RS14335	COG2059	Chromate
AZK53_RS14345	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AZK53_RS14350	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AZK53_RS14355	COG2508	Transcriptional regulator
AZK53_RS14360	COG0011	TIGRFAM Protein of
AZK53_RS14365	COG0791	NLP P60 protein
AZK53_RS14365	COG1388	LysM domain
AZK53_RS14370	COG0753	catalase activity
AZK53_RS14380	COG0733	neurotransmitter:sodium symporter activity
AZK53_RS14420	COG0730	response to heat
AZK53_RS14425	COG1902	pentaerythritol trinitrate reductase activity
AZK53_RS14440	COG2205	protein histidine kinase activity
AZK53_RS14450	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AZK53_RS14475	COG0640	Transcriptional regulator
AZK53_RS14485	COG0778	Nitroreductase
AZK53_RS14500	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AZK53_RS14505	COG4991	sh3 domain protein
AZK53_RS14505	COG0860	N-Acetylmuramoyl-L-alanine amidase
AZK53_RS14505	COG3103	Sh3 type 3 domain protein
AZK53_RS14510	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AZK53_RS14515	COG2002	toxin-antitoxin pair type II binding
AZK53_RS14520	COG2318	DinB family
AZK53_RS14525	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AZK53_RS14535	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AZK53_RS14540	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AZK53_RS14555	COG2211	Major facilitator Superfamily
AZK53_RS14560	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AZK53_RS14565	COG1597	lipid kinase activity
AZK53_RS14575	COG0372	Belongs to the citrate synthase family
AZK53_RS14580	COG0583	DNA-binding transcription factor activity
AZK53_RS14585	COG0697	spore germination
AZK53_RS14590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZK53_RS14605	COG1366	Belongs to the anti-sigma-factor antagonist family
AZK53_RS14605	COG2202	Pas domain
AZK53_RS14610	COG1366	Belongs to the anti-sigma-factor antagonist family
AZK53_RS14640	COG1366	Belongs to the anti-sigma-factor antagonist family
AZK53_RS14645	COG2261	transglycosylase associated protein
AZK53_RS14655	COG0740	serine-type endopeptidase activity
AZK53_RS14670	COG1027	Aspartate ammonia-lyase
AZK53_RS14675	COG0252	asparaginase activity
AZK53_RS14680	COG1396	sequence-specific DNA binding
AZK53_RS14695	COG0640	Transcriptional regulator
AZK53_RS14715	COG0531	amino acid
AZK53_RS14720	COG1959	2 iron, 2 sulfur cluster binding
AZK53_RS14740	COG0281	malic enzyme
AZK53_RS14745	COG2746	aminoglycoside 3-N-acetyltransferase activity
AZK53_RS14755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AZK53_RS14760	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_RS14770	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AZK53_RS14775	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AZK53_RS14785	COG0477	Major facilitator Superfamily
AZK53_RS14790	COG1846	Transcriptional regulator
AZK53_RS14795	COG0789	Transcriptional regulator
AZK53_RS14800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AZK53_RS14835	COG1819	glycosyl
AZK53_RS14850	COG1902	pentaerythritol trinitrate reductase activity
AZK53_RS14860	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AZK53_RS14875	COG2814	Major facilitator Superfamily
AZK53_RS14885	COG1228	amidohydrolase
AZK53_RS14895	COG1316	TRANSCRIPTIONal
AZK53_RS14900	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AZK53_RS14920	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AZK53_RS14930	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AZK53_RS14995	COG1280	lysine exporter protein (LysE YggA)
AZK53_RS15000	COG0531	amino acid
AZK53_RS15015	COG3764	Sortase (surface protein transpeptidase)
AZK53_RS15020	COG0730	response to heat
AZK53_RS15025	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AZK53_RS15030	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
AZK53_RS15040	COG2130	NADP-dependent
AZK53_RS15065	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AZK53_RS15080	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AZK53_RS15090	COG0501	Belongs to the peptidase M48B family
AZK53_RS15140	COG2076	Multidrug Resistance protein
AZK53_RS15145	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AZK53_RS15150	COG1278	Cold shock
AZK53_RS15155	COG2323	membrane
AZK53_RS15165	COG2910	NAD(P)H-binding
AZK53_RS15190	COG4607	ABC-type enterochelin transport system periplasmic component
AZK53_RS15195	COG4604	ABC transporter, ATP-binding protein
AZK53_RS15200	COG4605	iron ion homeostasis
AZK53_RS15205	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AZK53_RS15210	COG3773	Cell wall hydrolase
AZK53_RS15230	COG1063	alcohol dehydrogenase
AZK53_RS15235	COG3775	system Galactitol-specific IIC component
AZK53_RS15240	COG3414	Phosphotransferase system galactitol-specific IIB component
AZK53_RS15245	COG3414	Phosphotransferase system galactitol-specific IIB component
AZK53_RS15260	COG2249	NAD(P)H dehydrogenase (quinone) activity
AZK53_RS15265	COG0681	Belongs to the peptidase S26 family
AZK53_RS15295	COG1349	DNA-binding transcription factor activity
AZK53_RS15310	COG1193	negative regulation of DNA recombination
AZK53_RS15320	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AZK53_RS15325	COG1396	sequence-specific DNA binding
AZK53_RS15330	COG0861	Integral membrane protein TerC family
AZK53_RS15335	COG1609	Transcriptional regulator
AZK53_RS15340	COG1959	2 iron, 2 sulfur cluster binding
AZK53_RS15400	COG3773	Cell wall hydrolase
AZK53_RS15405	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AZK53_RS15430	COG3546	catalase activity
AZK53_RS15450	COG1280	lysine exporter protein (LysE YggA)
AZK53_RS15455	COG1917	Cupin 2, conserved barrel domain protein
AZK53_RS15455	COG2207	Transcriptional regulator
AZK53_RS15460	COG4585	Histidine kinase
AZK53_RS15480	COG3209	COG3209 Rhs family protein
AZK53_RS15500	COG1819	glycosyl
AZK53_RS15505	COG0456	acetyltransferase
AZK53_RS15520	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AZK53_RS15530	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AZK53_RS15550	COG0346	lactoylglutathione lyase activity
AZK53_RS15555	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AZK53_RS15570	COG1136	(ABC) transporter
AZK53_RS15575	COG0577	efflux transmembrane transporter activity
AZK53_RS15580	COG5002	protein histidine kinase activity
AZK53_RS15580	COG3850	Histidine kinase
AZK53_RS15605	COG5002	protein histidine kinase activity
AZK53_RS15610	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AZK53_RS15615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZK53_RS15640	COG4989	oxidoreductase activity
AZK53_RS15650	COG0697	spore germination
AZK53_RS15655	COG1917	Cupin 2, conserved barrel domain protein
AZK53_RS15655	COG2207	Transcriptional regulator
AZK53_RS15730	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
AZK53_RS15740	COG0583	DNA-binding transcription factor activity
AZK53_RS15750	COG1301	dicarboxylic acid transport
AZK53_RS15755	COG2824	Alkylphosphonate utilization operon protein PhnA
AZK53_RS15785	COG0405	Gamma-glutamyltransferase
AZK53_RS15805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZK53_RS15810	COG4521	taurine ABC transporter
AZK53_RS15815	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AZK53_RS15820	COG2175	clavaminate synthase activity
AZK53_RS15825	COG2814	Major facilitator Superfamily
AZK53_RS15845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZK53_RS15855	COG1960	acyl-CoA dehydrogenase activity
AZK53_RS15860	COG1063	alcohol dehydrogenase
AZK53_RS15865	COG0745	RESPONSE REGULATOR receiver
AZK53_RS15870	COG0642	Histidine kinase
AZK53_RS15875	COG1136	(ABC) transporter
AZK53_RS15880	COG0577	efflux transmembrane transporter activity
AZK53_RS15890	COG0412	Dienelactone hydrolase
AZK53_RS15895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZK53_RS15900	COG0730	response to heat
AZK53_RS15905	COG0425	Belongs to the sulfur carrier protein TusA family
AZK53_RS15910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AZK53_RS15910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZK53_RS15915	COG0425	Belongs to the sulfur carrier protein TusA family
AZK53_RS15915	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AZK53_RS15930	COG2210	Belongs to the sulfur carrier protein TusA family
AZK53_RS15935	COG0425	Belongs to the sulfur carrier protein TusA family
AZK53_RS15940	COG1937	Protein conserved in bacteria
AZK53_RS15965	COG0583	DNA-binding transcription factor activity
AZK53_RS15985	COG2188	Transcriptional regulator
AZK53_RS15995	COG2723	6-phospho-beta-galactosidase activity
AZK53_RS16020	COG1280	lysine exporter protein (LysE YggA)
AZK53_RS16035	COG0583	DNA-binding transcription factor activity
AZK53_RS16040	COG2814	Major facilitator Superfamily
AZK53_RS16045	COG0346	lactoylglutathione lyase activity
AZK53_RS16060	COG2723	6-phospho-beta-galactosidase activity
AZK53_RS16065	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AZK53_RS16080	COG0778	Nitroreductase
AZK53_RS16085	COG1012	belongs to the aldehyde dehydrogenase family
AZK53_RS16100	COG1704	LemA family
AZK53_RS16105	COG0726	polysaccharide deacetylase
AZK53_RS16120	COG1733	regulation of RNA biosynthetic process
AZK53_RS16125	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AZK53_RS16130	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AZK53_RS16135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AZK53_RS16150	COG2304	oxidoreductase activity
AZK53_RS16160	COG0346	lactoylglutathione lyase activity
AZK53_RS16165	COG2808	Putative FMN-binding domain
AZK53_RS16195	COG4807	Protein conserved in bacteria
AZK53_RS16205	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
AZK53_RS16210	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AZK53_RS16215	COG1278	Cold shock
AZK53_RS16220	COG1278	Cold shock
AZK53_RS16235	COG0747	negative chemotaxis
AZK53_RS16240	COG0601	transmembrane transport
AZK53_RS16245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZK53_RS16250	COG0444	Belongs to the ABC transporter superfamily
AZK53_RS16255	COG4608	Belongs to the ABC transporter superfamily
AZK53_RS16265	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AZK53_RS16270	COG1301	dicarboxylic acid transport
AZK53_RS16280	COG0477	Major facilitator Superfamily
AZK53_RS16320	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AZK53_RS16325	COG0659	secondary active sulfate transmembrane transporter activity
AZK53_RS16335	COG2211	Major facilitator Superfamily
AZK53_RS16340	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
AZK53_RS16345	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
AZK53_RS16350	COG1691	(AIR) carboxylase
AZK53_RS16355	COG1606	tRNA processing
AZK53_RS16360	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_RS16370	COG1904	glucuronate isomerase
AZK53_RS16405	COG2329	Antibiotic biosynthesis monooxygenase
AZK53_RS16445	COG3655	Transcriptional regulator
AZK53_RS16455	COG0583	DNA-binding transcription factor activity
AZK53_RS16460	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_RS16475	COG1609	Transcriptional regulator
AZK53_RS16480	COG1082	Xylose isomerase domain protein TIM barrel
AZK53_RS16485	COG0673	inositol 2-dehydrogenase activity
AZK53_RS16505	COG3718	enzyme involved in inositol metabolism
AZK53_RS16510	COG3962	Belongs to the TPP enzyme family
AZK53_RS16515	COG1349	DNA-binding transcription factor activity
AZK53_RS16520	COG0191	fructose-bisphosphate aldolase activity
AZK53_RS16525	COG1082	Xylose isomerase domain protein TIM barrel
AZK53_RS16530	COG2814	Major facilitator Superfamily
AZK53_RS16545	COG1064	alcohol dehydrogenase
AZK53_RS16550	COG0789	Transcriptional regulator
AZK53_RS16565	COG0662	Cupin 2, conserved barrel domain protein
AZK53_RS16585	COG1366	Belongs to the anti-sigma-factor antagonist family
AZK53_RS16590	COG1278	Cold shock
AZK53_RS16595	COG1876	peptidase activity
AZK53_RS16615	COG0598	Magnesium transport protein CorA
AZK53_RS16620	COG1366	Belongs to the anti-sigma-factor antagonist family
AZK53_RS16630	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_RS16640	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_RS16650	COG4335	DNA alkylation repair
AZK53_RS16655	COG0454	-acetyltransferase
AZK53_RS16670	COG2814	Major facilitator Superfamily
AZK53_RS16675	COG3848	Pyruvate phosphate dikinase
AZK53_RS16675	COG0574	Belongs to the PEP-utilizing enzyme family
AZK53_RS16680	COG0574	Belongs to the PEP-utilizing enzyme family
AZK53_RS16680	COG3848	Pyruvate phosphate dikinase
AZK53_RS16695	COG2186	Transcriptional regulator
AZK53_RS16715	COG3619	membrane
AZK53_RS16725	COG1349	DNA-binding transcription factor activity
AZK53_RS16730	COG0561	phosphatase activity
AZK53_RS16740	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AZK53_RS16760	COG1280	lysine exporter protein (LysE YggA)
AZK53_RS16775	COG3153	acetyltransferase
AZK53_RS16775	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AZK53_RS16785	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AZK53_RS16800	COG2814	Major facilitator Superfamily
AZK53_RS16805	COG2160	L-arabinose isomerase activity
AZK53_RS16820	COG1609	Transcriptional regulator
AZK53_RS16825	COG1078	dGTPase activity
AZK53_RS16845	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AZK53_RS16850	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AZK53_RS16855	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AZK53_RS16855	COG1918	ferrous iron import across plasma membrane
AZK53_RS16880	COG1846	Transcriptional regulator
AZK53_RS16910	COG0697	spore germination
AZK53_RS16915	COG1388	LysM domain
AZK53_RS16915	COG0791	NLP P60 protein
AZK53_RS16920	COG2258	MOSC domain
AZK53_RS16925	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AZK53_RS16960	COG4974	Belongs to the 'phage' integrase family
AZK53_RS17005	COG3844	kynureninase activity
AZK53_RS17010	COG1113	amino acid transport
AZK53_RS17015	COG3483	tryptophan 2,3-dioxygenase activity
AZK53_RS17020	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AZK53_RS17025	COG1942	4-Oxalocrotonate Tautomerase
AZK53_RS17055	COG0251	oxidation-reduction process
AZK53_RS17070	COG0431	NADPH-dependent FMN reductase
AZK53_RS17075	COG0196	riboflavin kinase activity
AZK53_RS17080	COG2368	4-hydroxyphenylacetate
AZK53_RS17100	COG0789	Transcriptional regulator
AZK53_RS17135	COG5646	InterPro IPR014922
AZK53_RS17140	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
AZK53_RS17170	COG2258	MOSC domain
AZK53_RS17190	COG0583	DNA-binding transcription factor activity
AZK53_RS17195	COG2070	2-Nitropropane dioxygenase
AZK53_RS17200	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AZK53_RS17215	COG1376	ErfK ybiS ycfS ynhG family protein
AZK53_RS17245	COG1012	belongs to the aldehyde dehydrogenase family
AZK53_RS17250	COG2188	Transcriptional regulator
AZK53_RS17260	COG1501	Belongs to the glycosyl hydrolase 31 family
AZK53_RS17270	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AZK53_RS17280	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
AZK53_RS17290	COG0300	oxidoreductase activity
AZK53_RS17300	COG0596	Alpha beta hydrolase
AZK53_RS17300	COG0508	dehydrogenase complex catalyzes the overall conversion of
AZK53_RS17305	COG1309	transcriptional regulator
AZK53_RS17310	COG1733	regulation of RNA biosynthetic process
AZK53_RS17315	COG2249	NAD(P)H dehydrogenase (quinone) activity
AZK53_RS17320	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AZK53_RS17325	COG2226	methyltransferase
AZK53_RS17340	COG1942	4-Oxalocrotonate Tautomerase
AZK53_RS17345	COG0583	DNA-binding transcription factor activity
AZK53_RS17355	COG1522	sequence-specific DNA binding
AZK53_RS17365	COG2267	carboxylic ester hydrolase activity
AZK53_RS17375	COG1335	isochorismatase
AZK53_RS17385	COG0346	lactoylglutathione lyase activity
AZK53_RS17390	COG2259	Doxx family
AZK53_RS17415	COG1309	transcriptional regulator
AZK53_RS17420	COG2076	Multidrug Resistance protein
AZK53_RS17450	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AZK53_RS17460	COG2851	Citrate transporter
AZK53_RS17470	COG0477	Major facilitator Superfamily
AZK53_RS17480	COG0477	Major facilitator Superfamily
AZK53_RS17485	COG1309	transcriptional regulator
AZK53_RS17495	COG2318	DinB family
AZK53_RS17505	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AZK53_RS17520	COG1378	Sugar-specific transcriptional regulator TrmB
AZK53_RS17525	COG0697	spore germination
AZK53_RS17535	COG0583	DNA-binding transcription factor activity
AZK53_RS17575	COG1266	CAAX protease self-immunity
AZK53_RS17600	COG0252	asparaginase activity
AZK53_RS17620	COG1695	Transcriptional regulator
AZK53_RS17625	COG0656	L-ascorbic acid biosynthetic process
AZK53_RS17635	COG0583	DNA-binding transcription factor activity
AZK53_RS17645	COG2814	Major facilitator Superfamily
AZK53_RS17650	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_RS17670	COG1309	transcriptional regulator
AZK53_RS17720	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AZK53_RS17785	COG3339	Conserved Protein
AZK53_RS17800	COG2207	Transcriptional regulator
AZK53_RS17800	COG3708	Transcriptional regulator
AZK53_RS17815	COG1357	PFAM Pentapeptide repeats (8 copies)
AZK53_RS17825	COG2249	NAD(P)H dehydrogenase (quinone) activity
AZK53_RS17830	COG1733	regulation of RNA biosynthetic process
AZK53_RS17870	COG0303	'Molybdopterin
AZK53_RS17880	COG0521	Mo-molybdopterin cofactor biosynthetic process
AZK53_RS17885	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AZK53_RS17890	COG1079	Belongs to the binding-protein-dependent transport system permease family
AZK53_RS17895	COG4603	Belongs to the binding-protein-dependent transport system permease family
AZK53_RS17900	COG3845	ABC transporter
AZK53_RS17915	COG2244	polysaccharide biosynthetic process
AZK53_RS17935	COG2828	Protein conserved in bacteria
AZK53_RS17940	COG0583	DNA-binding transcription factor activity
AZK53_RS17945	COG2851	Citrate transporter
AZK53_RS17960	COG0670	Belongs to the BI1 family
AZK53_RS17980	COG0791	NLP P60 protein
AZK53_RS17985	COG2814	Major facilitator Superfamily
AZK53_RS17990	COG1846	Transcriptional regulator
AZK53_RS18005	COG1278	Cold shock
AZK53_RS18015	COG1113	amino acid transport
AZK53_RS18020	COG1113	amino acid transport
AZK53_RS18025	COG1012	belongs to the aldehyde dehydrogenase family
AZK53_RS18030	COG0506	proline dehydrogenase activity
AZK53_RS18035	COG3878	Protein conserved in bacteria
AZK53_RS18050	COG0860	N-Acetylmuramoyl-L-alanine amidase
AZK53_RS18055	COG5001	Diguanylate cyclase
AZK53_RS18055	COG3300	MHYT domain
AZK53_RS18100	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AZK53_RS18105	COG5609	conserved protein (DUF2294)
AZK53_RS18140	COG0454	-acetyltransferase
AZK53_RS18150	COG0789	Transcriptional regulator
AZK53_RS18155	COG0667	Aldo Keto reductase
AZK53_RS18165	COG0789	Transcriptional regulator
AZK53_RS18190	COG1621	beta-fructofuranosidase activity
AZK53_RS18195	COG4980	gas vesicle protein
AZK53_RS18220	COG1752	Esterase of the alpha-beta hydrolase superfamily
AZK53_RS18225	COG0577	efflux transmembrane transporter activity
AZK53_RS18230	COG1136	(ABC) transporter
AZK53_RS18240	COG0642	Histidine kinase
AZK53_RS18255	COG1289	transmembrane transporter activity
AZK53_RS18260	COG1937	Protein conserved in bacteria
AZK53_RS18265	COG3209	COG3209 Rhs family protein
AZK53_RS18275	COG3973	AAA domain
AZK53_RS18280	COG1024	Enoyl-CoA hydratase
AZK53_RS18285	COG1733	regulation of RNA biosynthetic process
AZK53_RS18300	COG2124	cytochrome p450
AZK53_RS18305	COG2259	Doxx family
AZK53_RS18310	COG0463	Glycosyl transferase, family 2
AZK53_RS18320	COG0463	Glycosyl transferase, family 2
AZK53_RS18335	COG0791	NLP P60 protein
AZK53_RS18335	COG1388	LysM domain
AZK53_RS18340	COG0840	transmembrane signaling receptor activity
AZK53_RS18345	COG1846	Transcriptional regulator
AZK53_RS18355	COG1595	DNA-templated transcription, initiation
AZK53_RS18360	COG0726	polysaccharide deacetylase
AZK53_RS18365	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AZK53_RS18380	COG0833	amino acid
AZK53_RS18390	COG0405	Gamma-glutamyltransferase
AZK53_RS18400	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AZK53_RS18405	COG0569	domain protein
AZK53_RS18415	COG1522	sequence-specific DNA binding
AZK53_RS18425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AZK53_RS18430	COG0745	RESPONSE REGULATOR receiver
AZK53_RS18435	COG2205	protein histidine kinase activity
AZK53_RS18435	COG2770	Histidine kinase
AZK53_RS18440	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AZK53_RS18445	COG1607	acyl-coa hydrolase
AZK53_RS18450	COG1802	Transcriptional regulator
AZK53_RS18455	COG0697	spore germination
AZK53_RS18465	COG0006	proline dipeptidase activity
AZK53_RS18485	COG2249	NAD(P)H dehydrogenase (quinone) activity
AZK53_RS18490	COG5522	Integral membrane protein (intg_mem_TP0381)
AZK53_RS18495	COG1174	glycine betaine transport
AZK53_RS18500	COG0517	IMP dehydrogenase activity
AZK53_RS18500	COG1125	glycine betaine transport
AZK53_RS18515	COG2814	Major facilitator Superfamily
AZK53_RS18525	COG0395	ABC-type sugar transport system, permease component
AZK53_RS18545	COG1609	Transcriptional regulator
AZK53_RS18550	COG2205	protein histidine kinase activity
AZK53_RS18555	COG0730	response to heat
AZK53_RS18560	COG1301	dicarboxylic acid transport
AZK53_RS18575	COG0753	catalase activity
AZK53_RS18600	COG1368	sulfuric ester hydrolase activity
AZK53_RS18610	COG0697	spore germination
AZK53_RS18615	COG1902	pentaerythritol trinitrate reductase activity
AZK53_RS18630	COG1113	amino acid transport
AZK53_RS18635	COG5505	Protein of unknown function (DUF819)
AZK53_RS18640	COG1309	transcriptional regulator
AZK53_RS18650	COG0583	DNA-binding transcription factor activity
AZK53_RS18655	COG0730	response to heat
AZK53_RS18660	COG1247	-acetyltransferase
AZK53_RS18665	COG2910	NAD(P)H-binding
AZK53_RS18670	COG1285	pathogenesis
AZK53_RS18675	COG2226	methyltransferase
AZK53_RS18680	COG4195	phage-related replication protein
AZK53_RS18685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZK53_RS18700	COG1113	amino acid transport
AZK53_RS18725	COG0463	Glycosyl transferase, family 2
AZK53_RS18750	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AZK53_RS18755	COG2514	catechol 2,3-dioxygenase activity
AZK53_RS18775	COG1280	lysine exporter protein (LysE YggA)
AZK53_RS18780	COG1115	amino acid carrier protein
AZK53_RS18790	COG0385	Bile acid
AZK53_RS18795	COG0668	transmembrane transport
AZK53_RS18800	COG2340	Cysteine-rich secretory protein family
AZK53_RS18805	COG1253	flavin adenine dinucleotide binding
AZK53_RS18815	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AZK53_RS18820	COG0589	response to stress
AZK53_RS18825	COG0205	6-phosphofructokinase activity
AZK53_RS18830	COG0791	NLP P60 protein
AZK53_RS18830	COG1388	LysM domain
AZK53_RS18840	COG0432	Pfam Uncharacterised protein family UPF0047
AZK53_RS18845	COG0697	spore germination
AZK53_RS18850	COG0814	amino acid
AZK53_RS18875	COG1131	(ABC) transporter
AZK53_RS18890	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AZK53_RS18905	COG0584	glycerophosphoryl diester phosphodiesterase
AZK53_RS18915	COG1131	(ABC) transporter
AZK53_RS18930	COG0706	membrane insertase activity
AZK53_RS18940	COG1263	PTS System
AZK53_RS18940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AZK53_RS18945	COG3711	transcriptional antiterminator
AZK53_RS18950	COG2190	(PTS) system
AZK53_RS18955	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AZK53_RS18970	COG0772	Belongs to the SEDS family
AZK53_RS18975	COG0659	secondary active sulfate transmembrane transporter activity
AZK53_RS18980	COG0813	purine-nucleoside phosphorylase activity
AZK53_RS18990	COG0671	phosphoesterase, PA-phosphatase related
AZK53_RS18995	COG4326	sporulation control protein
AZK53_RS19000	COG0515	serine threonine protein kinase
AZK53_RS19000	COG2815	serine threonine protein kinase
AZK53_RS19015	COG4479	Belongs to the UPF0346 family
AZK53_RS19020	COG3594	Acyltransferase
AZK53_RS19035	COG1509	lysine 2,3-aminomutase activity
AZK53_RS19040	COG0456	acetyltransferase
AZK53_RS19045	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AZK53_RS19050	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AZK53_RS19055	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AZK53_RS19060	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AZK53_RS19065	COG1301	dicarboxylic acid transport
AZK53_RS19075	COG4191	Histidine kinase
AZK53_RS19095	COG2755	lipolytic protein G-D-S-L family
AZK53_RS19100	COG1999	signal sequence binding
AZK53_RS19110	COG1307	EDD domain protein, DegV family
AZK53_RS19120	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AZK53_RS19130	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AZK53_RS19135	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AZK53_RS19140	COG0788	formyltetrahydrofolate deformylase activity
AZK53_RS19170	COG0076	glutamate decarboxylase activity
AZK53_RS19190	COG0415	Belongs to the DNA photolyase family
AZK53_RS19195	COG3852	Histidine kinase
AZK53_RS19210	COG1012	belongs to the aldehyde dehydrogenase family
AZK53_RS19220	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AZK53_RS19230	COG4846	Membrane protein involved in cytochrome C biogenesis
AZK53_RS19235	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
AZK53_RS19240	COG0785	Cytochrome C biogenesis protein
AZK53_RS19250	COG1132	(ABC) transporter
AZK53_RS19255	COG1132	(ABC) transporter
AZK53_RS19275	COG4224	UPF0291 protein
AZK53_RS19280	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AZK53_RS19300	COG0463	Glycosyl transferase, family 2
AZK53_RS19305	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AZK53_RS19310	COG0531	amino acid
AZK53_RS19320	COG0174	glutamine synthetase
AZK53_RS19325	COG0789	Transcriptional regulator
AZK53_RS19330	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
AZK53_RS19335	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AZK53_RS19340	COG2860	membrane
AZK53_RS19345	COG0464	growth
AZK53_RS19355	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AZK53_RS19365	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AZK53_RS19370	COG0531	amino acid
AZK53_RS19380	COG4550	Control of competence regulator ComK, YlbF/YmcA
AZK53_RS19385	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AZK53_RS19390	COG1013	pyruvate-flavodoxin oxidoreductase activity
AZK53_RS19395	COG0674	pyruvate-flavodoxin oxidoreductase activity
AZK53_RS19395	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AZK53_RS19405	COG2359	stage V sporulation protein S
AZK53_RS19410	COG1692	metallophosphoesterase
AZK53_RS19420	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AZK53_RS19425	COG1058	Belongs to the CinA family
AZK53_RS19425	COG1546	Belongs to the CinA family
AZK53_RS19430	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AZK53_RS19435	COG1426	Protein conserved in bacteria
AZK53_RS19450	COG0300	oxidoreductase activity
AZK53_RS19455	COG0612	Peptidase, M16
AZK53_RS19460	COG0612	Peptidase, M16
AZK53_RS19465	COG1079	Belongs to the binding-protein-dependent transport system permease family
AZK53_RS19470	COG4603	Belongs to the binding-protein-dependent transport system permease family
AZK53_RS19475	COG3845	ABC transporter
AZK53_RS19480	COG1744	ABC transporter substrate-binding protein PnrA-like
AZK53_RS19485	COG2188	Transcriptional regulator
AZK53_RS19490	COG4980	gas vesicle protein
AZK53_RS19490	COG1674	ftsk spoiiie
AZK53_RS19500	COG0740	serine-type endopeptidase activity
AZK53_RS19505	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AZK53_RS19515	COG0527	aspartate kinase activity
AZK53_RS19520	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AZK53_RS19525	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AZK53_RS19530	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AZK53_RS19535	COG1873	PFAM PRC-barrel domain
AZK53_RS19540	COG0612	Peptidase, M16
AZK53_RS19545	COG0726	polysaccharide deacetylase
AZK53_RS19550	COG1185	polyribonucleotide nucleotidyltransferase activity
AZK53_RS19555	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AZK53_RS19560	COG0196	riboflavin kinase activity
AZK53_RS19570	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AZK53_RS19575	COG1550	Protein conserved in bacteria
AZK53_RS19585	COG1358	cellular component organization or biogenesis
AZK53_RS19590	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AZK53_RS19595	COG0195	Participates in both transcription termination and antitermination
AZK53_RS19600	COG0779	Required for maturation of 30S ribosomal subunits
AZK53_RS19605	COG2176	DNA-directed DNA polymerase activity
AZK53_RS19610	COG0442	prolyl-tRNA aminoacylation
AZK53_RS19615	COG0750	zinc metalloprotease
AZK53_RS19625	COG4589	Belongs to the CDS family
AZK53_RS19635	COG0233	cytoplasmic translational termination
AZK53_RS19645	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AZK53_RS19660	COG1191	sigma factor activity
AZK53_RS19665	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AZK53_RS19670	COG0835	chemotaxis
AZK53_RS19675	COG2198	Histidine kinase
AZK53_RS19675	COG0643	Histidine kinase
AZK53_RS19680	COG2201	protein-glutamate methylesterase activity
AZK53_RS19685	COG0455	bacterial-type flagellum organization
AZK53_RS19690	COG1419	protein localization to endoplasmic reticulum
AZK53_RS19695	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AZK53_RS19700	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AZK53_RS19705	COG1684	flagellar biosynthetic protein fliR
AZK53_RS19710	COG1987	bacterial-type flagellum assembly
AZK53_RS19715	COG1338	Plays a role in the flagellum-specific transport system
AZK53_RS19720	COG3190	flagellar
AZK53_RS19725	COG2201	protein-glutamate methylesterase activity
AZK53_RS19730	COG1776	CheC inhibitor of MCP methylation
AZK53_RS19730	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AZK53_RS19735	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AZK53_RS19745	COG1582	Flagellar protein (FlbD)
AZK53_RS19750	COG4786	Flagellar basal body rod
AZK53_RS19755	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AZK53_RS19770	COG2882	bacterial-type flagellum organization
AZK53_RS19775	COG1157	protein secretion by the type III secretion system
AZK53_RS19780	COG1317	bacterial-type flagellum organization
AZK53_RS19785	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AZK53_RS19790	COG1766	The M ring may be actively involved in energy transduction
AZK53_RS19795	COG1677	Flagellar hook-basal body complex protein FliE
AZK53_RS19800	COG1558	bacterial-type flagellum-dependent cell motility
AZK53_RS19805	COG1815	bacterial-type flagellum-dependent cell motility
AZK53_RS19810	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AZK53_RS19815	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AZK53_RS19825	COG4974	Belongs to the 'phage' integrase family
AZK53_RS19830	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AZK53_RS19835	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AZK53_RS19840	COG0758	DNA mediated transformation
AZK53_RS19845	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AZK53_RS19850	COG0045	succinate-CoA ligase (ADP-forming) activity
AZK53_RS19870	COG0335	large ribosomal subunit rRNA binding
AZK53_RS19880	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AZK53_RS19890	COG1837	Belongs to the UPF0109 family
AZK53_RS19895	COG0228	four-way junction DNA binding
AZK53_RS19900	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AZK53_RS19910	COG0552	protein localization to endoplasmic reticulum
AZK53_RS19915	COG1196	nuclear chromosome segregation
AZK53_RS19920	COG0571	ribonuclease III activity
AZK53_RS19930	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_RS19935	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AZK53_RS19940	COG0416	fatty acid biosynthetic process
AZK53_RS19945	COG1349	DNA-binding transcription factor activity
AZK53_RS19950	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AZK53_RS19955	COG1760	l-serine dehydratase
AZK53_RS19960	COG1760	l-serine dehydratase
AZK53_RS19970	COG1461	Dihydroxyacetone kinase
AZK53_RS19975	COG1302	Protein conserved in bacteria
AZK53_RS19980	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AZK53_RS19990	COG1564	THIamine pyrophosphokinase
AZK53_RS19995	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AZK53_RS20000	COG1162	GTPase activity
AZK53_RS20005	COG0515	serine threonine protein kinase
AZK53_RS20005	COG2815	serine threonine protein kinase
AZK53_RS20010	COG0631	protein serine/threonine phosphatase activity
AZK53_RS20020	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AZK53_RS20020	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AZK53_RS20025	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AZK53_RS20035	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AZK53_RS20040	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AZK53_RS20045	COG1758	RNA polymerase activity
AZK53_RS20050	COG0194	GDP metabolic process
AZK53_RS20055	COG2052	Domain of unknown function (DUF370)
AZK53_RS20060	COG1561	YicC-like family, N-terminal region
AZK53_RS20065	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AZK53_RS20075	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AZK53_RS20105	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AZK53_RS20110	COG0540	Belongs to the ATCase OTCase family
AZK53_RS20120	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AZK53_RS20125	COG0564	pseudouridine synthase activity
AZK53_RS20130	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AZK53_RS20145	COG3599	regulation of cell shape
AZK53_RS20150	COG2302	S4 RNA-binding domain
AZK53_RS20155	COG0762	integral membrane protein
AZK53_RS20160	COG1799	cell septum assembly
AZK53_RS20165	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AZK53_RS20175	COG1873	PFAM PRC-barrel domain
AZK53_RS20180	COG1191	sigma factor activity
AZK53_RS20185	COG1191	sigma factor activity
AZK53_RS20195	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AZK53_RS20200	COG0849	cell division
AZK53_RS20205	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AZK53_RS20210	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AZK53_RS20215	COG0772	Belongs to the SEDS family
AZK53_RS20220	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AZK53_RS20225	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AZK53_RS20230	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AZK53_RS20235	COG0768	penicillin binding
AZK53_RS20240	COG0768	penicillin binding
AZK53_RS20245	COG4839	cell division protein FtsL
AZK53_RS20255	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
AZK53_RS20265	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AZK53_RS20270	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AZK53_RS20275	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AZK53_RS20280	COG0439	Biotin carboxylase
AZK53_RS20285	COG0454	-acetyltransferase
AZK53_RS20295	COG1024	Enoyl-CoA hydratase
AZK53_RS20300	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AZK53_RS20305	COG1399	metal-binding, possibly nucleic acid-binding protein
AZK53_RS20310	COG1323	Belongs to the UPF0348 family
AZK53_RS20315	COG3480	Lon protease (S16) C-terminal proteolytic domain
AZK53_RS20325	COG3314	Sporulation integral membrane protein YlbJ
AZK53_RS20330	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AZK53_RS20335	COG0742	ribosomal rna small subunit methyltransferase
AZK53_RS20345	COG4471	UPF0298 protein
AZK53_RS20355	COG3679	Belongs to the UPF0342 family
AZK53_RS20375	COG4347	Protein of unknown function (DUF1405)
AZK53_RS20385	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AZK53_RS20400	COG5582	Belongs to the UPF0302 family
AZK53_RS20405	COG0457	Tetratricopeptide repeat
AZK53_RS20410	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AZK53_RS20415	COG0287	Prephenate dehydrogenase
AZK53_RS20420	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AZK53_RS20425	COG0159	tryptophan synthase activity
AZK53_RS20435	COG0135	phosphoribosylanthranilate isomerase activity
AZK53_RS20440	COG0134	indole-3-glycerol-phosphate synthase activity
AZK53_RS20445	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AZK53_RS20455	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AZK53_RS20460	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AZK53_RS20465	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AZK53_RS20470	COG0105	UTP biosynthetic process
AZK53_RS20475	COG0142	geranyltranstransferase activity
AZK53_RS20480	COG2226	methyltransferase
AZK53_RS20485	COG0142	geranyltranstransferase activity
AZK53_RS20495	COG0302	gtp cyclohydrolase
AZK53_RS20500	COG0776	regulation of translation
AZK53_RS20505	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AZK53_RS20535	COG2271	Major facilitator Superfamily
AZK53_RS20540	COG1304	FMN binding
AZK53_RS20545	COG0539	negative regulation of cytoplasmic translation
AZK53_RS20555	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AZK53_RS20565	COG2959	enzyme of heme biosynthesis
AZK53_RS20570	COG3409	Peptidoglycan-binding domain 1 protein
AZK53_RS20570	COG3773	Cell wall hydrolase
AZK53_RS20575	COG2339	peptidase activity
AZK53_RS20580	COG0252	asparaginase activity
AZK53_RS20585	COG0492	ferredoxin-NADP+ reductase activity
AZK53_RS20590	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AZK53_RS20595	COG4862	establishment of competence for transformation
AZK53_RS20600	COG0789	Transcriptional regulator
AZK53_RS20605	COG1408	metallophosphoesterase
AZK53_RS20620	COG1266	CAAX protease self-immunity
AZK53_RS20625	COG0514	ATP-dependent DNA helicase (RecQ)
AZK53_RS20635	COG1141	Ferredoxin
AZK53_RS20640	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AZK53_RS20645	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AZK53_RS20650	COG0739	heme binding
AZK53_RS20655	COG5002	protein histidine kinase activity
AZK53_RS20660	COG0745	RESPONSE REGULATOR receiver
AZK53_RS20665	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AZK53_RS20670	COG1333	cytochrome c biogenesis protein
AZK53_RS20675	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AZK53_RS20680	COG1187	pseudouridine synthase activity
AZK53_RS20685	COG0700	Nucleoside recognition
AZK53_RS20690	COG2715	membrane protein required for spore maturation
AZK53_RS20695	COG1686	Belongs to the peptidase S11 family
AZK53_RS20700	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AZK53_RS20705	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AZK53_RS20710	COG1547	Domain of unknown function (DUF309)
AZK53_RS20720	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AZK53_RS20725	COG4086	secreted protein
AZK53_RS20735	COG0697	spore germination
AZK53_RS20750	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AZK53_RS20785	COG1686	Belongs to the peptidase S11 family
AZK53_RS20800	COG4974	Belongs to the 'phage' integrase family
AZK53_RS20810	COG0735	belongs to the Fur family
AZK53_RS20815	COG1300	Membrane
AZK53_RS20820	COG0494	nUDIX hydrolase
AZK53_RS20830	COG0667	Aldo Keto reductase
AZK53_RS20840	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AZK53_RS20845	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AZK53_RS20855	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AZK53_RS20860	COG1073	alpha beta
AZK53_RS20875	COG0300	oxidoreductase activity
AZK53_RS20880	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZK53_RS20885	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AZK53_RS20890	COG1902	pentaerythritol trinitrate reductase activity
AZK53_RS20895	COG1234	tRNA 3'-trailer cleavage
AZK53_RS20900	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AZK53_RS20905	COG1012	belongs to the aldehyde dehydrogenase family
AZK53_RS20910	COG2508	Transcriptional regulator
AZK53_RS20930	COG0167	dihydroorotate dehydrogenase activity
AZK53_RS20930	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AZK53_RS20935	COG0493	'glutamate synthase
AZK53_RS20940	COG2195	Cleaves the N-terminal amino acid of tripeptides
AZK53_RS20945	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AZK53_RS20950	COG0346	lactoylglutathione lyase activity
AZK53_RS20955	COG1376	ErfK ybiS ycfS ynhG family protein
AZK53_RS20960	COG4129	membrane
AZK53_RS20965	COG1126	abc transporter atp-binding protein
AZK53_RS20970	COG0765	amino acid transport
AZK53_RS20975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZK53_RS20985	COG1703	isobutyryl-CoA mutase activity
AZK53_RS20990	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AZK53_RS20990	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AZK53_RS20995	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AZK53_RS20995	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AZK53_RS21000	COG0508	dehydrogenase complex catalyzes the overall conversion of
AZK53_RS21005	COG0022	dehydrogenase e1 component
AZK53_RS21010	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AZK53_RS21015	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AZK53_RS21030	COG0280	phosphate acetyltransferase
AZK53_RS21035	COG3290	protein histidine kinase activity
AZK53_RS21035	COG3829	transcription factor binding
AZK53_RS21045	COG0584	glycerophosphoryl diester phosphodiesterase
AZK53_RS21050	COG3104	oligopeptide transport
AZK53_RS21055	COG0745	RESPONSE REGULATOR receiver
AZK53_RS21060	COG0750	zinc metalloprotease
AZK53_RS21065	COG0497	DNA recombination
AZK53_RS21075	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AZK53_RS21090	COG1722	exodeoxyribonuclease VII activity
AZK53_RS21100	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AZK53_RS21105	COG1302	Protein conserved in bacteria
AZK53_RS21110	COG0439	Biotin carboxylase
AZK53_RS21115	COG0511	ligase activity, forming carbon-carbon bonds
AZK53_RS21155	COG3854	ATPases associated with a variety of cellular activities
AZK53_RS21165	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AZK53_RS21170	COG0006	proline dipeptidase activity
AZK53_RS21175	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AZK53_RS21185	COG3872	metal-dependent enzyme
AZK53_RS21195	COG1752	Esterase of the alpha-beta hydrolase superfamily
AZK53_RS21200	COG1321	iron dependent repressor
AZK53_RS21205	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AZK53_RS21210	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AZK53_RS21215	COG0095	Lipoate-protein ligase
AZK53_RS21220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AZK53_RS21230	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AZK53_RS21235	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AZK53_RS21240	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AZK53_RS21270	COG4970	Tfp pilus assembly protein FimT
AZK53_RS21275	COG4537	Required for transformation and DNA binding
AZK53_RS21280	COG1459	type II secretion system
AZK53_RS21285	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AZK53_RS21290	COG1393	Belongs to the ArsC family
AZK53_RS21300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZK53_RS21310	COG1940	carbohydrate kinase activity
AZK53_RS21315	COG4483	Protein conserved in bacteria
AZK53_RS21320	COG0705	Rhomboid family
AZK53_RS21320	COG0457	Tetratricopeptide repeat
AZK53_RS21330	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AZK53_RS21340	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AZK53_RS21355	COG0704	Plays a role in the regulation of phosphate uptake
AZK53_RS21365	COG0768	penicillin binding
AZK53_RS21370	COG0477	Major facilitator Superfamily
AZK53_RS21405	COG2839	Protein conserved in bacteria
AZK53_RS21415	COG2814	Major facilitator Superfamily
AZK53_RS21420	COG1388	LysM domain
AZK53_RS21425	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AZK53_RS21430	COG4709	membrane
AZK53_RS21435	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
AZK53_RS21440	COG0735	belongs to the Fur family
AZK53_RS21445	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AZK53_RS21450	COG1121	(ABC) transporter
AZK53_RS21460	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AZK53_RS21465	COG0513	Belongs to the DEAD box helicase family
AZK53_RS21475	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AZK53_RS21480	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AZK53_RS21485	COG2384	SAM-dependent methyltransferase
AZK53_RS21490	COG2010	Cytochrome c
AZK53_RS21500	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AZK53_RS21505	COG0358	DNA primase activity
AZK53_RS21510	COG1671	Belongs to the UPF0178 family
AZK53_RS21515	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AZK53_RS21520	COG0517	IMP dehydrogenase activity
AZK53_RS21530	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AZK53_RS21535	COG0295	cytidine deaminase activity
AZK53_RS21540	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AZK53_RS21550	COG1480	7TM receptor with intracellular HD hydrolase
AZK53_RS21555	COG1702	phosphate starvation-inducible protein PhoH
AZK53_RS21580	COG1030	water channel activity
AZK53_RS21585	COG1610	YqeY-like protein
AZK53_RS21595	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AZK53_RS21600	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AZK53_RS21605	COG2264	protein methyltransferase activity
AZK53_RS21620	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AZK53_RS21625	COG1420	regulation of RNA biosynthetic process
AZK53_RS21630	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AZK53_RS21635	COG0481	GTPase activity
AZK53_RS21645	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AZK53_RS21650	COG0268	Binds directly to 16S ribosomal RNA
AZK53_RS21655	COG1466	dna polymerase III delta subunit
AZK53_RS21660	COG2333	competence protein COMEC
AZK53_RS21660	COG0658	competence protein
AZK53_RS21665	COG2131	deaminase
AZK53_RS21670	COG1596	polysaccharide export
AZK53_RS21670	COG1555	photosystem II stabilization
AZK53_RS21675	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AZK53_RS21680	COG2226	methyltransferase
AZK53_RS21685	COG0799	negative regulation of ribosome biogenesis
AZK53_RS21690	COG1713	HD superfamily hydrolase involved in NAD metabolism
AZK53_RS21695	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AZK53_RS21700	COG1534	Rna-binding protein
AZK53_RS21705	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AZK53_RS21710	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AZK53_RS21715	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AZK53_RS21725	COG0688	phosphatidylethanolamine metabolic process
AZK53_RS21730	COG1183	phosphatidylcholine synthase activity
AZK53_RS21745	COG0626	cystathionine gamma-synthase activity
AZK53_RS21750	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AZK53_RS21755	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AZK53_RS21760	COG2226	methyltransferase
AZK53_RS21775	COG0768	penicillin binding
AZK53_RS21780	COG1335	isochorismatase
AZK53_RS21785	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AZK53_RS21790	COG0572	uridine kinase
AZK53_RS21795	COG0826	peptidase U32
AZK53_RS21800	COG0826	peptidase U32
AZK53_RS21805	COG4122	O-methyltransferase activity
AZK53_RS21810	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AZK53_RS21815	COG3906	Belongs to the UPF0473 family
AZK53_RS21825	COG4472	Bacterial protein of unknown function (DUF965)
AZK53_RS21835	COG0628	permease
AZK53_RS21845	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AZK53_RS21855	COG0482	sulfurtransferase activity
AZK53_RS21860	COG1104	cysteine desulfurase activity
AZK53_RS21865	COG1959	2 iron, 2 sulfur cluster binding
AZK53_RS21870	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AZK53_RS21875	COG0581	inorganic phosphate transmembrane transporter activity
AZK53_RS21880	COG0573	inorganic phosphate transmembrane transporter activity
AZK53_RS21885	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AZK53_RS21890	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AZK53_RS21900	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AZK53_RS21905	COG0124	histidyl-tRNA synthetase
AZK53_RS21915	COG0860	N-Acetylmuramoyl-L-alanine amidase
AZK53_RS21920	COG1490	D-aminoacyl-tRNA deacylase activity
AZK53_RS21925	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AZK53_RS21930	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AZK53_RS21935	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AZK53_RS21935	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AZK53_RS21940	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AZK53_RS21940	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AZK53_RS21950	COG2244	polysaccharide biosynthetic process
AZK53_RS21955	COG2323	membrane
AZK53_RS21965	COG1862	Preprotein translocase
AZK53_RS21970	COG0343	queuine tRNA-ribosyltransferase activity
AZK53_RS21975	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AZK53_RS21985	COG2255	four-way junction helicase activity
AZK53_RS21990	COG0632	four-way junction helicase activity
AZK53_RS22015	COG1388	LysM domain
AZK53_RS22020	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AZK53_RS22025	COG0157	Belongs to the NadC ModD family
AZK53_RS22030	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AZK53_RS22035	COG1104	cysteine desulfurase activity
AZK53_RS22040	COG1827	regulation of RNA biosynthetic process
AZK53_RS22045	COG0077	Prephenate dehydratase
AZK53_RS22050	COG4492	Belongs to the UPF0735 family
AZK53_RS22055	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AZK53_RS22060	COG3290	protein histidine kinase activity
AZK53_RS22070	COG2868	ribosomal protein
AZK53_RS22080	COG1530	ribonuclease E activity
AZK53_RS22085	COG1994	Peptidase M50
AZK53_RS22090	COG0739	heme binding
AZK53_RS22095	COG2894	cell division
AZK53_RS22100	COG0850	regulation of cytokinetic process
AZK53_RS22105	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AZK53_RS22110	COG1792	Involved in formation and maintenance of cell shape
AZK53_RS22115	COG1077	Cell shape determining protein MreB Mrl
AZK53_RS22120	COG2003	Belongs to the UPF0758 family
AZK53_RS22125	COG0424	maF-like protein
AZK53_RS22135	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AZK53_RS22145	COG2322	membrane
AZK53_RS22150	COG0285	dihydrofolate synthase activity
AZK53_RS22155	COG0525	valine-tRNA ligase activity
AZK53_RS22165	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AZK53_RS22170	COG1388	LysM domain
AZK53_RS22175	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AZK53_RS22180	COG0113	porphobilinogen synthase activity
AZK53_RS22185	COG1587	Uroporphyrinogen-III synthase
AZK53_RS22190	COG0181	hydroxymethylbilane synthase activity
AZK53_RS22195	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AZK53_RS22210	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AZK53_RS22215	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AZK53_RS22220	COG1067	ATP-dependent peptidase activity
AZK53_RS22220	COG0470	DNA polymerase III
AZK53_RS22225	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AZK53_RS22230	COG0544	peptidyl-prolyl cis-trans isomerase activity
AZK53_RS22235	COG1477	protein flavinylation
AZK53_RS22235	COG0457	Tetratricopeptide repeat
AZK53_RS22240	COG0066	3-isopropylmalate dehydratase activity
AZK53_RS22245	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AZK53_RS22255	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AZK53_RS22260	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AZK53_RS22265	COG0440	acetolactate synthase activity
AZK53_RS22270	COG0028	Belongs to the TPP enzyme family
AZK53_RS22280	COG0622	Phosphoesterase
AZK53_RS22295	COG5401	PFAM Sporulation and spore germination
AZK53_RS22300	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AZK53_RS22305	COG1846	Transcriptional regulator
AZK53_RS22315	COG0306	phosphate transporter
AZK53_RS22320	COG1392	Phosphate transport regulator
AZK53_RS22325	COG0768	penicillin binding
AZK53_RS22335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZK53_RS22340	COG0431	NADPH-dependent FMN reductase
AZK53_RS22345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZK53_RS22350	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZK53_RS22355	COG1116	anion transmembrane transporter activity
AZK53_RS22360	COG0475	glutathione-regulated potassium exporter activity
AZK53_RS22365	COG0490	domain, Protein
AZK53_RS22375	COG2197	response regulator
AZK53_RS22380	COG0824	Thioesterase
AZK53_RS22385	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AZK53_RS22390	COG1053	succinate dehydrogenase
AZK53_RS22395	COG2009	succinate dehydrogenase
AZK53_RS22400	COG1719	4-vinyl reductase, 4VR
AZK53_RS22405	COG0527	aspartate kinase activity
AZK53_RS22415	COG3118	belongs to the thioredoxin family
AZK53_RS22420	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AZK53_RS22425	COG2086	electron transfer activity
AZK53_RS22430	COG1024	Enoyl-CoA hydratase
AZK53_RS22435	COG1309	transcriptional regulator
AZK53_RS22440	COG0318	PFAM AMP-dependent synthetase and ligase
AZK53_RS22445	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AZK53_RS22450	COG3766	membrane
AZK53_RS22455	COG1193	negative regulation of DNA recombination
AZK53_RS22460	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AZK53_RS22460	COG1796	DNA polymerase
AZK53_RS22465	COG1286	toxin biosynthetic process
AZK53_RS22470	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AZK53_RS22475	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AZK53_RS22480	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AZK53_RS22480	COG0072	phenylalanine-tRNA ligase activity
AZK53_RS22485	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AZK53_RS22490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AZK53_RS22500	COG1363	Peptidase, m42
AZK53_RS22520	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AZK53_RS22525	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AZK53_RS22530	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AZK53_RS22535	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AZK53_RS22550	COG1484	DNA-dependent DNA replication
AZK53_RS22555	COG3611	Membrane attachment protein
AZK53_RS22560	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AZK53_RS22570	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AZK53_RS22575	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AZK53_RS22580	COG0237	dephospho-CoA kinase activity
AZK53_RS22585	COG1971	Probably functions as a manganese efflux pump
AZK53_RS22590	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AZK53_RS22595	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AZK53_RS22595	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AZK53_RS22600	COG5002	protein histidine kinase activity
AZK53_RS22605	COG0745	RESPONSE REGULATOR receiver
AZK53_RS22615	COG0039	L-malate dehydrogenase activity
AZK53_RS22620	COG0538	isocitrate dehydrogenase activity
AZK53_RS22625	COG0372	Belongs to the citrate synthase family
AZK53_RS22630	COG2707	UPF0756 membrane protein
AZK53_RS22635	COG0628	permease
AZK53_RS22640	COG3030	protein affecting phage T7 exclusion by the F plasmid
AZK53_RS22650	COG0825	malonyl-CoA metabolic process
AZK53_RS22655	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AZK53_RS22660	COG2186	Transcriptional regulator
AZK53_RS22665	COG0281	malic enzyme
AZK53_RS22670	COG0587	DNA-directed DNA polymerase activity
AZK53_RS22685	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AZK53_RS22695	COG4109	DRTGG domain
AZK53_RS22705	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AZK53_RS22715	COG0165	Argininosuccinate lyase
AZK53_RS22720	COG0137	argininosuccinate synthase activity
AZK53_RS22735	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AZK53_RS22740	COG0827	DNA restriction-modification system
AZK53_RS22745	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AZK53_RS22750	COG3874	Sporulation protein YtfJ
AZK53_RS22760	COG1714	RDD family
AZK53_RS22765	COG0616	signal peptide processing
AZK53_RS22770	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AZK53_RS22775	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AZK53_RS22785	COG0301	tRNA thio-modification
AZK53_RS22790	COG1104	cysteine desulfurase activity
AZK53_RS22795	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AZK53_RS22800	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AZK53_RS22805	COG1309	transcriptional regulator
AZK53_RS22810	COG1956	GAF domain-containing protein
AZK53_RS22825	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AZK53_RS22830	COG0454	-acetyltransferase
AZK53_RS22835	COG0517	IMP dehydrogenase activity
AZK53_RS22840	COG0123	including yeast histone deacetylase and acetoin utilization protein
AZK53_RS22860	COG1605	Chorismate mutase
AZK53_RS22860	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AZK53_RS22865	COG3118	belongs to the thioredoxin family
AZK53_RS22870	COG4980	gas vesicle protein
AZK53_RS22885	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AZK53_RS22895	COG1674	ftsk spoiiie
AZK53_RS22900	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AZK53_RS22905	COG4848	Belongs to the UPF0354 family
AZK53_RS22910	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AZK53_RS22915	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
AZK53_RS22920	COG1363	Peptidase, m42
AZK53_RS22925	COG5584	Small secreted protein
AZK53_RS22930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZK53_RS22935	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AZK53_RS22945	COG0510	thiamine kinase activity
AZK53_RS22950	COG1523	belongs to the glycosyl hydrolase 13 family
AZK53_RS22960	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AZK53_RS22965	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AZK53_RS22970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AZK53_RS22975	COG1349	DNA-binding transcription factor activity
AZK53_RS22980	COG1187	pseudouridine synthase activity
AZK53_RS22985	COG2244	polysaccharide biosynthetic process
AZK53_RS22990	COG2081	HI0933 family
AZK53_RS23000	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AZK53_RS23005	COG0495	leucyl-tRNA aminoacylation
AZK53_RS23015	COG2610	gluconate transmembrane transporter activity
AZK53_RS23020	COG2814	Major facilitator Superfamily
AZK53_RS23035	COG1242	4 iron, 4 sulfur cluster binding
AZK53_RS23040	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AZK53_RS23050	COG2267	carboxylic ester hydrolase activity
AZK53_RS23055	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AZK53_RS23060	COG0671	phosphoesterase, PA-phosphatase related
AZK53_RS23065	COG0438	transferase activity, transferring glycosyl groups
AZK53_RS23070	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AZK53_RS23075	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AZK53_RS23085	COG1506	peptidase
AZK53_RS23090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZK53_RS23095	COG1116	anion transmembrane transporter activity
AZK53_RS23100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZK53_RS23105	COG0494	nUDIX hydrolase
AZK53_RS23115	COG4824	toxin secretion phage lysis holin
AZK53_RS23120	COG0783	Belongs to the Dps family
AZK53_RS23130	COG0288	reversible hydration of carbon dioxide
AZK53_RS23135	COG0523	cobalamin synthesis protein
AZK53_RS23145	COG0254	rRNA binding
AZK53_RS23150	COG1271	oxidase subunit
AZK53_RS23155	COG1294	oxidase, subunit
AZK53_RS23160	COG0716	FMN binding
AZK53_RS23180	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AZK53_RS23185	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AZK53_RS23190	COG4948	Mandelate Racemase Muconate Lactonizing
AZK53_RS23195	COG0318	PFAM AMP-dependent synthetase and ligase
AZK53_RS23200	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AZK53_RS23205	COG0596	Alpha beta hydrolase
AZK53_RS23210	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AZK53_RS23215	COG1169	isochorismate synthase
AZK53_RS23220	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AZK53_RS23230	COG0058	SHG alpha-glucan phosphorylase activity
AZK53_RS23235	COG0297	glycogen (starch) synthase activity
AZK53_RS23240	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AZK53_RS23245	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AZK53_RS23375	COG0318	PFAM AMP-dependent synthetase and ligase
AZK53_RS23380	COG1285	pathogenesis
AZK53_RS23400	COG0529	Catalyzes the synthesis of activated sulfate
AZK53_RS23410	COG0306	phosphate transporter
AZK53_RS23420	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AZK53_RS23425	COG0346	lactoylglutathione lyase activity
AZK53_RS23430	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AZK53_RS23440	COG0166	Belongs to the GPI family
AZK53_RS23450	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AZK53_RS23450	COG2111	Na H antiporter
AZK53_RS23455	COG2111	Na H antiporter
AZK53_RS23460	COG1006	Multisubunit Na H antiporter MnhC subunit
AZK53_RS23465	COG0651	ATP synthesis coupled electron transport
AZK53_RS23470	COG1863	multisubunit Na H antiporter MnhE subunit
AZK53_RS23475	COG2212	antiporter activity
AZK53_RS23480	COG1320	monovalent cation:proton antiporter activity
AZK53_RS23485	COG1979	alcohol dehydrogenase
AZK53_RS23490	COG2155	Conserved Protein
AZK53_RS23495	COG1098	S1 RNA binding domain
AZK53_RS23500	COG0436	Aminotransferase
AZK53_RS23505	COG1522	sequence-specific DNA binding
AZK53_RS23510	COG2267	carboxylic ester hydrolase activity
AZK53_RS23515	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AZK53_RS23520	COG2032	superoxide dismutase activity
AZK53_RS23535	COG5018	Exonuclease
AZK53_RS23540	COG2050	protein possibly involved in aromatic compounds catabolism
AZK53_RS23550	COG1418	mRNA catabolic process
AZK53_RS23560	COG2056	Na+-H+ antiporter family
AZK53_RS23565	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AZK53_RS23570	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
AZK53_RS23575	COG3584	3D domain protein
AZK53_RS23585	COG1252	NADH dehydrogenase
AZK53_RS23590	COG0492	ferredoxin-NADP+ reductase activity
AZK53_RS23600	COG0316	Belongs to the HesB IscA family
AZK53_RS23605	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AZK53_RS23615	COG4844	belongs to the
AZK53_RS23620	COG1252	NADH dehydrogenase
AZK53_RS23625	COG4837	Protein of unknown function (DUF1462)
AZK53_RS23630	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AZK53_RS23635	COG0083	homoserine kinase activity
AZK53_RS23640	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AZK53_RS23645	COG0460	homoserine dehydrogenase
AZK53_RS23650	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AZK53_RS23655	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AZK53_RS23660	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AZK53_RS23665	COG0647	UMP catabolic process
AZK53_RS23670	COG2445	Protein of unknown function DUF86
AZK53_RS23680	COG4470	Protein conserved in bacteria
AZK53_RS23690	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AZK53_RS23695	COG0739	heme binding
AZK53_RS23700	COG0733	neurotransmitter:sodium symporter activity
AZK53_RS23710	COG3377	Domain of unknown function (DUF1805)
AZK53_RS23715	COG1801	Protein of unknown function DUF72
AZK53_RS23720	COG0719	Fe-S assembly protein
AZK53_RS23725	COG0822	iron-sulfur transferase activity
AZK53_RS23730	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AZK53_RS23735	COG0719	Fe-S assembly protein
AZK53_RS23740	COG0396	ATPase activity
AZK53_RS23745	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AZK53_RS23750	COG1464	Belongs to the NlpA lipoprotein family
AZK53_RS23755	COG2011	ABC-type metal ion transport system permease component
AZK53_RS23760	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AZK53_RS23765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AZK53_RS23770	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AZK53_RS23780	COG0509	glycine decarboxylation via glycine cleavage system
AZK53_RS23785	COG1393	Belongs to the ArsC family
AZK53_RS23790	COG1960	acyl-CoA dehydrogenase activity
AZK53_RS23795	COG0183	Belongs to the thiolase family
AZK53_RS23800	COG1024	Enoyl-CoA hydratase
AZK53_RS23800	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZK53_RS23820	COG1120	ATPase activity
AZK53_RS23825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AZK53_RS23830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AZK53_RS23835	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AZK53_RS23840	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AZK53_RS23845	COG1309	transcriptional regulator
AZK53_RS23855	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_RS23860	COG0477	Major facilitator Superfamily
AZK53_RS23870	COG5002	protein histidine kinase activity
AZK53_RS23870	COG3850	Histidine kinase
AZK53_RS23875	COG0745	RESPONSE REGULATOR receiver
AZK53_RS23880	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AZK53_RS23885	COG0671	phosphoesterase, PA-phosphatase related
AZK53_RS23890	COG1846	Transcriptional regulator
AZK53_RS23895	COG0778	Nitroreductase
AZK53_RS23900	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AZK53_RS23905	COG0314	molybdopterin synthase activity
AZK53_RS23910	COG1763	Mo-molybdopterin cofactor biosynthetic process
AZK53_RS23915	COG0303	'Molybdopterin
AZK53_RS23920	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AZK53_RS23925	COG0746	molybdenum cofactor guanylyltransferase activity
AZK53_RS23935	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AZK53_RS23940	COG5609	conserved protein (DUF2294)
AZK53_RS23945	COG3383	formate dehydrogenase (NAD+) activity
AZK53_RS23950	COG2427	Protein of unknown function (DUF1641)
AZK53_RS23955	COG0725	ABC transporter, periplasmic molybdate-binding protein
AZK53_RS23960	COG4149	molybdate abc transporter
AZK53_RS23970	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AZK53_RS23975	COG0557	exoribonuclease II activity
AZK53_RS23980	COG1647	Serine aminopeptidase, S33
AZK53_RS23985	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AZK53_RS23995	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AZK53_RS24025	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AZK53_RS24045	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AZK53_RS24055	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AZK53_RS24060	COG1660	Displays ATPase and GTPase activities
AZK53_RS24065	COG1051	belongs to the nudix hydrolase family
AZK53_RS24070	COG0492	ferredoxin-NADP+ reductase activity
AZK53_RS24075	COG0457	Tetratricopeptide repeat
AZK53_RS24080	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AZK53_RS24080	COG0140	phosphoribosyl-ATP diphosphatase activity
AZK53_RS24085	COG0107	imidazoleglycerol-phosphate synthase activity
AZK53_RS24090	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AZK53_RS24095	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AZK53_RS24100	COG0131	Imidazoleglycerol-phosphate dehydratase
AZK53_RS24105	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AZK53_RS24110	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AZK53_RS24115	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AZK53_RS24120	COG0110	maltose O-acetyltransferase activity
AZK53_RS24125	COG0546	phosphoglycolate phosphatase activity
AZK53_RS24130	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AZK53_RS24135	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AZK53_RS24140	COG1950	PFAM Membrane protein of
AZK53_RS24145	COG1983	PspC domain protein
AZK53_RS24150	COG3595	metallopeptidase activity
AZK53_RS24160	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AZK53_RS24165	COG0556	nucleotide-excision repair
AZK53_RS24170	COG2204	response regulator
AZK53_RS24175	COG1012	belongs to the aldehyde dehydrogenase family
AZK53_RS24180	COG0506	proline dehydrogenase activity
AZK53_RS24185	COG4897	Protein conserved in bacteria
AZK53_RS24190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AZK53_RS24195	COG3409	Peptidoglycan-binding domain 1 protein
AZK53_RS24195	COG0793	Belongs to the peptidase S41A family
AZK53_RS24200	COG0739	heme binding
AZK53_RS24205	COG2177	Part of the ABC transporter FtsEX involved in
AZK53_RS24210	COG2884	Cell division ATP-binding protein ftsE
AZK53_RS24215	COG0655	NAD(P)H dehydrogenase (quinone) activity
AZK53_RS24225	COG0805	protein transport
AZK53_RS24230	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AZK53_RS24235	COG3540	Alkaline phosphatase
AZK53_RS24240	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AZK53_RS24245	COG0653	protein targeting
AZK53_RS24250	COG0456	acetyltransferase
AZK53_RS24255	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AZK53_RS24265	COG1516	flagellar protein fliS
AZK53_RS24270	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AZK53_RS24280	COG1113	amino acid transport
AZK53_RS24290	COG1012	belongs to the aldehyde dehydrogenase family
AZK53_RS24295	COG1454	alcohol dehydrogenase
AZK53_RS24300	COG1510	regulation of RNA biosynthetic process
AZK53_RS24305	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AZK53_RS24310	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
AZK53_RS24315	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AZK53_RS24320	COG4786	Flagellar basal body rod
AZK53_RS24320	COG1256	bacterial-type flagellum assembly
AZK53_RS24340	COG1040	competence protein
AZK53_RS24345	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AZK53_RS24350	COG1307	EDD domain protein, DegV family
AZK53_RS24355	COG1728	Protein conserved in bacteria
AZK53_RS24365	COG2197	response regulator
AZK53_RS24370	COG4585	Histidine kinase
AZK53_RS24375	COG1739	Uncharacterized protein family UPF0029
AZK53_RS24380	COG1316	TRANSCRIPTIONal
AZK53_RS24385	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AZK53_RS24390	COG1585	Membrane protein implicated in regulation of membrane protease activity
AZK53_RS24395	COG2268	Band 7 protein
AZK53_RS24400	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AZK53_RS24410	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AZK53_RS24420	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AZK53_RS24425	COG0791	NLP P60 protein
AZK53_RS24425	COG1388	LysM domain
AZK53_RS24430	COG0629	single-stranded DNA binding
AZK53_RS24455	COG4786	Flagellar basal body rod
AZK53_RS24460	COG4786	Flagellar basal body rod
AZK53_RS24465	COG1077	Cell shape determining protein MreB Mrl
AZK53_RS24470	COG1609	Transcriptional regulator
AZK53_RS24475	COG0739	heme binding
AZK53_RS24480	COG2385	sporulation resulting in formation of a cellular spore
AZK53_RS24495	COG4836	Membrane
AZK53_RS24500	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AZK53_RS24505	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AZK53_RS24510	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AZK53_RS24515	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AZK53_RS24520	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AZK53_RS24525	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AZK53_RS24530	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AZK53_RS24535	COG0356	it plays a direct role in the translocation of protons across the membrane
AZK53_RS24550	COG1404	Belongs to the peptidase S8 family
AZK53_RS24555	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AZK53_RS24560	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AZK53_RS24575	COG0698	ribose 5-phosphate isomerase
AZK53_RS24585	COG1971	Probably functions as a manganese efflux pump
AZK53_RS24590	COG0009	L-threonylcarbamoyladenylate synthase
AZK53_RS24610	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AZK53_RS24625	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AZK53_RS24635	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AZK53_RS24640	COG0191	fructose-bisphosphate aldolase activity
AZK53_RS24645	COG2204	response regulator
AZK53_RS24650	COG4821	SIS domain
AZK53_RS24655	COG0504	CTP synthase activity
AZK53_RS24665	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AZK53_RS24665	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AZK53_RS24665	COG1703	isobutyryl-CoA mutase activity
AZK53_RS24675	COG1960	acyl-CoA dehydrogenase activity
AZK53_RS24680	COG1960	acyl-CoA dehydrogenase activity
AZK53_RS24685	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZK53_RS24695	COG2181	nitrate reductase activity
AZK53_RS24695	COG0247	lactate metabolic process
AZK53_RS24700	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AZK53_RS24705	COG4294	response to UV
AZK53_RS24710	COG0018	arginyl-trna synthetase
AZK53_RS24715	COG4506	Protein conserved in bacteria
AZK53_RS24720	COG0010	Belongs to the arginase family
AZK53_RS24725	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AZK53_RS24730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AZK53_RS24740	COG1994	Peptidase M50
AZK53_RS24745	COG1942	4-Oxalocrotonate Tautomerase
AZK53_RS24750	COG3465	dGTPase activity
AZK53_RS24755	COG1078	dGTPase activity
AZK53_RS24760	COG4844	belongs to the
AZK53_RS24770	COG0095	Lipoate-protein ligase
AZK53_RS24775	COG0280	phosphate acetyltransferase
AZK53_RS24780	COG3253	May function as heme-dependent peroxidase
AZK53_RS24785	COG3773	Cell wall hydrolase
AZK53_RS24795	COG2363	Small membrane protein
AZK53_RS24805	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AZK53_RS24815	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AZK53_RS24820	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AZK53_RS24825	COG2508	Transcriptional regulator
AZK53_RS24825	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AZK53_RS24830	COG0686	Belongs to the AlaDH PNT family
AZK53_RS24840	COG0351	phosphomethylpyrimidine kinase
AZK53_RS24845	COG0561	phosphatase activity
AZK53_RS24850	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AZK53_RS24855	COG1263	PTS System
AZK53_RS24855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AZK53_RS24855	COG2190	(PTS) system
AZK53_RS24865	COG0438	transferase activity, transferring glycosyl groups
AZK53_RS24880	COG2076	Multidrug Resistance protein
AZK53_RS24890	COG0728	peptidoglycan biosynthetic process
AZK53_RS24905	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AZK53_RS24910	COG4988	ABC transporter
AZK53_RS24915	COG1294	oxidase, subunit
AZK53_RS24920	COG1271	oxidase subunit
AZK53_RS24925	COG3610	response to peptide
AZK53_RS24930	COG2966	Psort location CytoplasmicMembrane, score
AZK53_RS24935	COG1609	Transcriptional regulator
AZK53_RS24945	COG2814	Major facilitator Superfamily
AZK53_RS24960	COG1966	Carbon starvation protein
AZK53_RS24965	COG0753	catalase activity
AZK53_RS24975	COG0471	metal ion transport
AZK53_RS24980	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AZK53_RS24990	COG0745	RESPONSE REGULATOR receiver
AZK53_RS24995	COG5002	protein histidine kinase activity
AZK53_RS25010	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AZK53_RS25015	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AZK53_RS25025	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AZK53_RS25030	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AZK53_RS25035	COG4853	Protein conserved in bacteria
AZK53_RS25045	COG5002	protein histidine kinase activity
AZK53_RS25050	COG0745	RESPONSE REGULATOR receiver
AZK53_RS25075	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AZK53_RS25080	COG0305	Participates in initiation and elongation during chromosome replication
AZK53_RS25090	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
AZK53_RS25100	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AZK53_RS25110	COG0360	Binds together with S18 to 16S ribosomal RNA
AZK53_RS25115	COG0012	GTP binding
AZK53_RS25120	COG4481	Protein conserved in bacteria
AZK53_RS25125	COG0668	transmembrane transport
AZK53_RS25130	COG3949	Membrane
AZK53_RS25140	COG1475	DNA binding
AZK53_RS25145	COG1192	Involved in chromosome partitioning
AZK53_RS25150	COG1475	DNA binding
AZK53_RS25160	COG0445	tRNA wobble uridine modification
AZK53_RS25165	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AZK53_RS25170	COG1847	R3H domain protein
AZK53_RS25175	COG0706	membrane insertase activity
AZK53_RS25180	COG0594	ribonuclease P activity
AZK53_RS25185	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AZK53_RS25190	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AZK53_RS25195	COG0592	DNA-directed DNA polymerase activity
AZK53_RS25200	COG2501	S4 domain
AZK53_RS25205	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AZK53_RS25210	COG0187	DNA topoisomerase II activity
AZK53_RS25215	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AZK53_RS25250	COG0517	IMP dehydrogenase activity
AZK53_RS25250	COG0516	GMP reductase activity
AZK53_RS25265	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AZK53_RS25280	COG1428	Deoxynucleoside kinase
AZK53_RS25285	COG1428	Deoxynucleoside kinase
AZK53_RS25290	COG3858	chitin binding
AZK53_RS25290	COG1388	LysM domain
AZK53_RS25295	COG1335	isochorismatase
AZK53_RS25300	COG0590	tRNA wobble adenosine to inosine editing
AZK53_RS25310	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AZK53_RS25315	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AZK53_RS25320	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AZK53_RS25425	COG1982	Orn Lys Arg decarboxylase major
AZK53_RS25450	COG5583	Uncharacterized small protein (DUF2292)
AZK53_RS25470	COG3093	addiction module antidote protein HigA