locus-tag	class	description
NL113_RS00030	COG0697	spore germination
NL113_RS00035	COG1802	Transcriptional regulator
NL113_RS00040	COG4112	unkown
NL113_RS00045	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NL113_RS00050	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NL113_RS00055	COG1780	Probably involved in ribonucleotide reductase function
NL113_RS00065	COG1923	regulation of RNA biosynthetic process
NL113_RS00070	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NL113_RS00085	COG2076	Multidrug Resistance protein
NL113_RS00090	COG2076	Multidrug Resistance protein
NL113_RS00095	COG1764	response to oxidative stress
NL113_RS00105	COG0702	epimerase
NL113_RS00110	COG3631	Ketosteroid isomerase-related protein
NL113_RS00115	COG1309	transcriptional regulator
NL113_RS00120	COG3858	chitin binding
NL113_RS00120	COG1388	LysM domain
NL113_RS00130	COG5577	PFAM Coat F domain
NL113_RS00135	COG0531	amino acid
NL113_RS00140	COG1819	glycosyl
NL113_RS00145	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NL113_RS00150	COG0398	Pfam SNARE associated Golgi protein
NL113_RS00155	COG0393	Putative heavy-metal-binding
NL113_RS00195	COG2814	Major facilitator Superfamily
NL113_RS00200	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NL113_RS00200	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
NL113_RS00205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NL113_RS00210	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NL113_RS00215	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NL113_RS00225	COG3263	regulation of cellular component size
NL113_RS00230	COG3619	membrane
NL113_RS00245	COG2135	peptidase activity
NL113_RS00310	COG5444	nuclease activity
NL113_RS00315	COG0346	lactoylglutathione lyase activity
NL113_RS00320	COG0640	Transcriptional regulator
NL113_RS00350	COG5444	nuclease activity
NL113_RS00355	COG0457	Tetratricopeptide repeat
NL113_RS00385	COG4282	regulation of fungal-type cell wall biogenesis
NL113_RS00425	COG1124	(ABC) transporter
NL113_RS00430	COG0444	Belongs to the ABC transporter superfamily
NL113_RS00435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NL113_RS00440	COG0601	transmembrane transport
NL113_RS00445	COG0747	negative chemotaxis
NL113_RS00465	COG0523	cobalamin synthesis protein
NL113_RS00475	COG3411	Ferredoxin
NL113_RS00480	COG0523	cobalamin synthesis protein
NL113_RS00485	COG0822	iron-sulfur transferase activity
NL113_RS00500	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
NL113_RS00505	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NL113_RS00510	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NL113_RS00520	COG4550	Control of competence regulator ComK, YlbF/YmcA
NL113_RS00525	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NL113_RS00530	COG0156	8-amino-7-oxononanoate synthase activity
NL113_RS00535	COG1063	alcohol dehydrogenase
NL113_RS00545	COG2359	stage V sporulation protein S
NL113_RS00550	COG1692	metallophosphoesterase
NL113_RS00555	COG1418	mRNA catabolic process
NL113_RS00565	COG1546	Belongs to the CinA family
NL113_RS00565	COG1058	Belongs to the CinA family
NL113_RS00570	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NL113_RS00575	COG1426	Protein conserved in bacteria
NL113_RS00590	COG0300	oxidoreductase activity
NL113_RS00595	COG0612	Peptidase, M16
NL113_RS00600	COG0612	Peptidase, M16
NL113_RS00605	COG2814	Major facilitator Superfamily
NL113_RS00610	COG2188	Transcriptional regulator
NL113_RS00615	COG1674	ftsk spoiiie
NL113_RS00615	COG4980	gas vesicle protein
NL113_RS00625	COG0740	serine-type endopeptidase activity
NL113_RS00630	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NL113_RS00640	COG0527	aspartate kinase activity
NL113_RS00645	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NL113_RS00650	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NL113_RS00655	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NL113_RS00660	COG1873	PFAM PRC-barrel domain
NL113_RS00665	COG0612	Peptidase, M16
NL113_RS00670	COG0726	polysaccharide deacetylase
NL113_RS00675	COG1185	polyribonucleotide nucleotidyltransferase activity
NL113_RS00680	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NL113_RS00685	COG0196	riboflavin kinase activity
NL113_RS00690	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NL113_RS00695	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NL113_RS00700	COG1550	Protein conserved in bacteria
NL113_RS00705	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NL113_RS00710	COG1358	cellular component organization or biogenesis
NL113_RS00715	COG2740	Nucleic-acid-binding protein implicated in transcription termination
NL113_RS00720	COG0195	Participates in both transcription termination and antitermination
NL113_RS00725	COG0779	Required for maturation of 30S ribosomal subunits
NL113_RS00750	COG2176	DNA-directed DNA polymerase activity
NL113_RS00755	COG0442	prolyl-tRNA aminoacylation
NL113_RS00760	COG0750	zinc metalloprotease
NL113_RS00765	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NL113_RS00770	COG4589	Belongs to the CDS family
NL113_RS00775	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NL113_RS00780	COG0233	cytoplasmic translational termination
NL113_RS00785	COG0528	UMP kinase activity
NL113_RS00790	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NL113_RS00795	COG0052	Belongs to the universal ribosomal protein uS2 family
NL113_RS00805	COG1191	sigma factor activity
NL113_RS00810	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
NL113_RS00815	COG1776	CheC inhibitor of MCP methylation
NL113_RS00820	COG0835	chemotaxis
NL113_RS00825	COG0643	Histidine kinase
NL113_RS00825	COG2198	Histidine kinase
NL113_RS00830	COG2201	protein-glutamate methylesterase activity
NL113_RS00835	COG0455	bacterial-type flagellum organization
NL113_RS00840	COG1419	protein localization to endoplasmic reticulum
NL113_RS00845	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NL113_RS00850	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NL113_RS00855	COG1684	flagellar biosynthetic protein fliR
NL113_RS00860	COG1987	bacterial-type flagellum assembly
NL113_RS00865	COG1338	Plays a role in the flagellum-specific transport system
NL113_RS00870	COG3190	flagellar
NL113_RS00875	COG2201	protein-glutamate methylesterase activity
NL113_RS00880	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NL113_RS00880	COG1776	CheC inhibitor of MCP methylation
NL113_RS00885	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NL113_RS00890	COG1580	Controls the rotational direction of flagella during chemotaxis
NL113_RS00895	COG1582	Flagellar protein (FlbD)
NL113_RS00900	COG4786	Flagellar basal body rod
NL113_RS00905	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
NL113_RS00910	COG3144	bacterial-type flagellum assembly
NL113_RS00920	COG2882	bacterial-type flagellum organization
NL113_RS00925	COG1157	protein secretion by the type III secretion system
NL113_RS00930	COG1317	bacterial-type flagellum organization
NL113_RS00935	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NL113_RS00940	COG1766	The M ring may be actively involved in energy transduction
NL113_RS00945	COG1677	Flagellar hook-basal body complex protein FliE
NL113_RS00950	COG1558	bacterial-type flagellum-dependent cell motility
NL113_RS00955	COG1815	bacterial-type flagellum-dependent cell motility
NL113_RS00960	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NL113_RS00965	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NL113_RS00970	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NL113_RS00975	COG4974	Belongs to the 'phage' integrase family
NL113_RS00980	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NL113_RS00985	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NL113_RS00990	COG0758	DNA mediated transformation
NL113_RS00995	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NL113_RS01000	COG0045	succinate-CoA ligase (ADP-forming) activity
NL113_RS01005	COG2257	FlhB HrpN YscU SpaS Family
NL113_RS01015	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NL113_RS01020	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NL113_RS01025	COG0335	large ribosomal subunit rRNA binding
NL113_RS01030	COG0336	Belongs to the RNA methyltransferase TrmD family
NL113_RS01035	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NL113_RS01045	COG1837	Belongs to the UPF0109 family
NL113_RS01050	COG0228	four-way junction DNA binding
NL113_RS01055	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NL113_RS01060	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NL113_RS01065	COG0552	protein localization to endoplasmic reticulum
NL113_RS01070	COG1196	nuclear chromosome segregation
NL113_RS01075	COG0571	ribonuclease III activity
NL113_RS01080	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NL113_RS01085	COG1028	Short-chain dehydrogenase reductase Sdr
NL113_RS01090	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NL113_RS01095	COG0416	fatty acid biosynthetic process
NL113_RS01100	COG1349	DNA-binding transcription factor activity
NL113_RS01105	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NL113_RS01110	COG1760	l-serine dehydratase
NL113_RS01115	COG1760	l-serine dehydratase
NL113_RS01120	COG1461	Dihydroxyacetone kinase
NL113_RS01125	COG1302	Protein conserved in bacteria
NL113_RS01130	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NL113_RS01140	COG1564	THIamine pyrophosphokinase
NL113_RS01145	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NL113_RS01150	COG1162	GTPase activity
NL113_RS01155	COG0515	serine threonine protein kinase
NL113_RS01155	COG2815	serine threonine protein kinase
NL113_RS01160	COG0631	protein serine/threonine phosphatase activity
NL113_RS01165	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NL113_RS01170	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NL113_RS01170	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NL113_RS01175	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NL113_RS01180	COG0242	peptide deformylase activity
NL113_RS01185	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NL113_RS01190	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NL113_RS01195	COG1758	RNA polymerase activity
NL113_RS01200	COG0194	GDP metabolic process
NL113_RS01205	COG2052	Domain of unknown function (DUF370)
NL113_RS01210	COG1561	YicC-like family, N-terminal region
NL113_RS01215	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NL113_RS01225	COG1648	precorrin-2 dehydrogenase activity
NL113_RS01230	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
NL113_RS01235	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NL113_RS01240	COG0529	Catalyzes the synthesis of activated sulfate
NL113_RS01245	COG2046	Belongs to the sulfate adenylyltransferase family
NL113_RS01250	COG0306	phosphate transporter
NL113_RS01255	COG0175	sulfate reduction
NL113_RS01265	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NL113_RS01270	COG0284	orotidine-5'-phosphate decarboxylase activity
NL113_RS01275	COG0167	dihydroorotate dehydrogenase activity
NL113_RS01280	COG0543	2 iron, 2 sulfur cluster binding
NL113_RS01285	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NL113_RS01290	COG0505	Belongs to the CarA family
NL113_RS01295	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NL113_RS01300	COG0540	Belongs to the ATCase OTCase family
NL113_RS01305	COG2233	PERMEase
NL113_RS01315	COG0564	pseudouridine synthase activity
NL113_RS01320	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NL113_RS01325	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NL113_RS01330	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NL113_RS01335	COG3599	regulation of cell shape
NL113_RS01340	COG2302	S4 RNA-binding domain
NL113_RS01345	COG0762	integral membrane protein
NL113_RS01350	COG1799	cell septum assembly
NL113_RS01355	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NL113_RS01360	COG1496	oxidoreductase activity
NL113_RS01365	COG1873	PFAM PRC-barrel domain
NL113_RS01370	COG0500	methyltransferase
NL113_RS01375	COG0457	Tetratricopeptide repeat
NL113_RS01380	COG1119	ATPase activity
NL113_RS01385	COG1191	sigma factor activity
NL113_RS01390	COG1191	sigma factor activity
NL113_RS01400	COG1404	Belongs to the peptidase S8 family
NL113_RS01400	COG4412	M6 family metalloprotease domain protein
NL113_RS01410	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NL113_RS01415	COG0849	cell division
NL113_RS01420	COG3856	small basic protein
NL113_RS01425	COG3879	Bacterial protein of unknown function (DUF881)
NL113_RS01430	COG3879	Bacterial protein of unknown function (DUF881)
NL113_RS01435	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NL113_RS01440	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NL113_RS01445	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NL113_RS01450	COG0772	Belongs to the SEDS family
NL113_RS01455	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NL113_RS01460	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NL113_RS01465	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NL113_RS01470	COG0768	penicillin binding
NL113_RS01475	COG0768	penicillin binding
NL113_RS01480	COG4839	cell division protein FtsL
NL113_RS01485	COG0275	rRNA processing
NL113_RS01490	COG2001	Belongs to the MraZ family
NL113_RS01495	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NL113_RS01500	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NL113_RS01505	COG0454	-acetyltransferase
NL113_RS01515	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NL113_RS01520	COG1399	metal-binding, possibly nucleic acid-binding protein
NL113_RS01525	COG1323	Belongs to the UPF0348 family
NL113_RS01530	COG3480	Lon protease (S16) C-terminal proteolytic domain
NL113_RS01535	COG3314	Sporulation integral membrane protein YlbJ
NL113_RS01540	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NL113_RS01545	COG0742	ribosomal rna small subunit methyltransferase
NL113_RS01550	COG4471	UPF0298 protein
NL113_RS01555	COG3679	Belongs to the UPF0342 family
NL113_RS01570	COG1834	amidinotransferase
NL113_RS01580	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NL113_RS01585	COG0583	DNA-binding transcription factor activity
NL113_RS01590	COG2340	Cysteine-rich secretory protein family
NL113_RS01595	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
NL113_RS01605	COG3336	cytochrome c oxidase
NL113_RS01610	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NL113_RS01615	COG1845	cytochrome c oxidase, subunit III
NL113_RS01620	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NL113_RS01625	COG2010	Cytochrome c
NL113_RS01625	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NL113_RS01630	COG0109	protoheme IX farnesyltransferase activity
NL113_RS01635	COG1612	heme a metabolic process
NL113_RS01640	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NL113_RS01645	COG0772	Belongs to the SEDS family
NL113_RS01650	COG4838	Belongs to the UPF0358 family
NL113_RS01655	COG2066	Belongs to the glutaminase family
NL113_RS01660	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NL113_RS01665	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NL113_RS01675	COG4896	Protein conserved in bacteria
NL113_RS01680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NL113_RS01685	COG1846	Transcriptional regulator
NL113_RS01695	COG1217	gtp-binding protein TYPA
NL113_RS01710	COG0483	inositol monophosphate 1-phosphatase activity
NL113_RS01720	COG4493	Belongs to the UPF0637 family
NL113_RS01725	COG4476	Belongs to the UPF0223 family
NL113_RS01730	COG1982	Orn Lys Arg decarboxylase major
NL113_RS01745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NL113_RS01750	COG0508	dehydrogenase complex catalyzes the overall conversion of
NL113_RS01755	COG0022	dehydrogenase e1 component
NL113_RS01760	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NL113_RS01765	COG0497	DNA recombination
NL113_RS01775	COG0242	peptide deformylase activity
NL113_RS01780	COG0561	phosphatase activity
NL113_RS01785	COG5503	Protein of unknown function (DUF1447)
NL113_RS01790	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NL113_RS01795	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NL113_RS01800	COG0569	domain protein
NL113_RS01805	COG3852	Histidine kinase
NL113_RS01810	COG2002	toxin-antitoxin pair type II binding
NL113_RS01815	COG1077	Cell shape determining protein MreB Mrl
NL113_RS01825	COG2309	aminopeptidase activity
NL113_RS01835	COG0488	(ABC) transporter
NL113_RS01855	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NL113_RS01855	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NL113_RS01855	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NL113_RS01860	COG1105	Belongs to the carbohydrate kinase PfkB family
NL113_RS01865	COG1349	DNA-binding transcription factor activity
NL113_RS01880	COG0577	efflux transmembrane transporter activity
NL113_RS01885	COG1136	(ABC) transporter
NL113_RS01890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NL113_RS01900	COG1132	(ABC) transporter
NL113_RS01905	COG1132	(ABC) transporter
NL113_RS01915	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NL113_RS01920	COG0314	molybdopterin synthase activity
NL113_RS01925	COG1763	Mo-molybdopterin cofactor biosynthetic process
NL113_RS01930	COG0303	'Molybdopterin
NL113_RS01935	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NL113_RS01940	COG0746	molybdenum cofactor guanylyltransferase activity
NL113_RS01955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NL113_RS01960	COG0450	alkyl hydroperoxide reductase
NL113_RS01970	COG1473	amidohydrolase
NL113_RS01975	COG2171	N-acyltransferase activity
NL113_RS01980	COG0716	FMN binding
NL113_RS01990	COG0716	FMN binding
NL113_RS01995	COG0583	DNA-binding transcription factor activity
NL113_RS02000	COG0517	IMP dehydrogenase activity
NL113_RS02010	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
NL113_RS02020	COG4703	Protein of unknown function (DUF1797)
NL113_RS02035	COG2200	EAL domain
NL113_RS02040	COG1028	Short-chain dehydrogenase reductase Sdr
NL113_RS02045	COG1408	metallophosphoesterase
NL113_RS02050	COG1376	ErfK ybiS ycfS ynhG family protein
NL113_RS02055	COG2814	Major facilitator Superfamily
NL113_RS02065	COG0784	Response regulator, receiver
NL113_RS02065	COG0835	chemotaxis
NL113_RS02075	COG1714	RDD family
NL113_RS02085	COG0436	Aminotransferase
NL113_RS02090	COG4191	Histidine kinase
NL113_RS02095	COG0768	penicillin binding
NL113_RS02100	COG2340	Cysteine-rich secretory protein family
NL113_RS02105	COG2084	Dehydrogenase
NL113_RS02110	COG1028	Short-chain dehydrogenase reductase Sdr
NL113_RS02115	COG0840	transmembrane signaling receptor activity
NL113_RS02120	COG0456	acetyltransferase
NL113_RS02125	COG1533	DNA photolyase activity
NL113_RS02135	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NL113_RS02140	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NL113_RS02145	COG1263	PTS System
NL113_RS02145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NL113_RS02145	COG2190	(PTS) system
NL113_RS02150	COG3711	transcriptional antiterminator
NL113_RS02155	COG1609	Transcriptional regulator
NL113_RS02165	COG0006	proline dipeptidase activity
NL113_RS02170	COG2217	Heavy metal translocating P-type atpase
NL113_RS02175	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NL113_RS02180	COG2244	polysaccharide biosynthetic process
NL113_RS02185	COG3773	Cell wall hydrolase
NL113_RS02195	COG4873	Protein conserved in bacteria
NL113_RS02205	COG0456	acetyltransferase
NL113_RS02210	COG1522	sequence-specific DNA binding
NL113_RS02215	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NL113_RS02250	COG0457	Tetratricopeptide repeat
NL113_RS02280	COG2378	regulation of single-species biofilm formation
NL113_RS02300	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NL113_RS02305	COG0602	queuosine metabolic process
NL113_RS02310	COG0720	synthase
NL113_RS02315	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NL113_RS02320	COG3949	Membrane
NL113_RS02325	COG0542	response to heat
NL113_RS02330	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NL113_RS02335	COG1360	Flagellar Motor Protein
NL113_RS02340	COG1846	Transcriptional regulator
NL113_RS02345	COG3852	Histidine kinase
NL113_RS02355	COG3339	Conserved Protein
NL113_RS02360	COG0346	lactoylglutathione lyase activity
NL113_RS02365	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NL113_RS02370	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NL113_RS02370	COG0235	Class ii aldolase
NL113_RS02375	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NL113_RS02375	COG0235	Class ii aldolase
NL113_RS02380	COG1850	ribulose-bisphosphate carboxylase activity
NL113_RS02385	COG0436	Aminotransferase
NL113_RS02390	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NL113_RS02395	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
NL113_RS02400	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NL113_RS02410	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NL113_RS02415	COG5002	protein histidine kinase activity
NL113_RS02420	COG3594	Acyltransferase
NL113_RS02435	COG0768	penicillin binding
NL113_RS02440	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NL113_RS02445	COG0501	Belongs to the peptidase M48B family
NL113_RS02475	COG1191	sigma factor activity
NL113_RS02485	COG0586	Pfam SNARE associated Golgi protein
NL113_RS02490	COG3300	MHYT domain
NL113_RS02490	COG5001	Diguanylate cyclase
NL113_RS02495	COG2203	Gaf domain
NL113_RS02495	COG4251	negative regulation of phosphorylation
NL113_RS02495	COG5001	Diguanylate cyclase
NL113_RS02495	COG3706	GGDEF domain
NL113_RS02500	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NL113_RS02505	COG3285	dna ligase
NL113_RS02505	COG1793	dna ligase
NL113_RS02510	COG1846	Transcriptional regulator
NL113_RS02525	COG0789	Transcriptional regulator
NL113_RS02535	COG2239	Acts as a magnesium transporter
NL113_RS02545	COG1404	Belongs to the peptidase S8 family
NL113_RS02550	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NL113_RS02570	COG0590	tRNA wobble adenosine to inosine editing
NL113_RS02580	COG1764	response to oxidative stress
NL113_RS02585	COG1846	Transcriptional regulator
NL113_RS02590	COG1764	response to oxidative stress
NL113_RS02595	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NL113_RS02600	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NL113_RS02605	COG0788	formyltetrahydrofolate deformylase activity
NL113_RS02610	COG2076	Multidrug Resistance protein
NL113_RS02615	COG2076	Multidrug Resistance protein
NL113_RS02620	COG2318	DinB family
NL113_RS02625	COG3866	Pectate lyase
NL113_RS02630	COG2323	membrane
NL113_RS02635	COG1607	acyl-coa hydrolase
NL113_RS02640	COG1834	amidinotransferase
NL113_RS02645	COG4608	Belongs to the ABC transporter superfamily
NL113_RS02650	COG0791	NLP P60 protein
NL113_RS02655	COG4948	Mandelate Racemase Muconate Lactonizing
NL113_RS02660	COG1619	proteins homologs of microcin C7 resistance protein MccF
NL113_RS02665	COG4166	transmembrane transport
NL113_RS02670	COG0444	Belongs to the ABC transporter superfamily
NL113_RS02675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NL113_RS02680	COG0601	transmembrane transport
NL113_RS02685	COG2362	D-Aminopeptidase
NL113_RS02690	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NL113_RS02695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NL113_RS02700	COG0346	lactoylglutathione lyase activity
NL113_RS02705	COG0531	amino acid
NL113_RS02710	COG0395	ABC-type sugar transport system, permease component
NL113_RS02715	COG4209	transmembrane transport
NL113_RS02720	COG1653	transport
NL113_RS02730	COG1874	Beta-galactosidase
NL113_RS02735	COG2755	lipolytic protein G-D-S-L family
NL113_RS02740	COG2755	lipolytic protein G-D-S-L family
NL113_RS02745	COG3401	FG-GAP repeat protein
NL113_RS02750	COG5578	integral membrane protein
NL113_RS02760	COG2755	lipolytic protein G-D-S-L family
NL113_RS02765	COG2207	Transcriptional regulator
NL113_RS02770	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NL113_RS02775	COG0395	ABC-type sugar transport system, permease component
NL113_RS02780	COG1175	transmembrane transport
NL113_RS02785	COG1653	transport
NL113_RS02790	COG2207	Transcriptional regulator
NL113_RS02790	COG4753	response regulator
NL113_RS02795	COG2972	Histidine kinase
NL113_RS02810	COG4208	sulfate ABC transporter
NL113_RS02820	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
NL113_RS02825	COG0405	Gamma-glutamyltransferase
NL113_RS02830	COG1392	Phosphate transport regulator
NL113_RS02835	COG0306	phosphate transporter
NL113_RS02850	COG2271	Major facilitator Superfamily
NL113_RS02855	COG1063	alcohol dehydrogenase
NL113_RS02860	COG1028	Short-chain dehydrogenase reductase Sdr
NL113_RS02865	COG1312	Catalyzes the dehydration of D-mannonate
NL113_RS02870	COG1063	alcohol dehydrogenase
NL113_RS02875	COG1802	Transcriptional regulator
NL113_RS02915	COG1595	DNA-templated transcription, initiation
NL113_RS02935	COG1396	sequence-specific DNA binding
NL113_RS02940	COG2856	Zn peptidase
NL113_RS02945	COG4195	phage-related replication protein
NL113_RS02960	COG0697	spore germination
NL113_RS02965	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NL113_RS02985	COG1309	transcriptional regulator
NL113_RS02990	COG2814	Major facilitator Superfamily
NL113_RS02995	COG5434	Belongs to the glycosyl hydrolase 28 family
NL113_RS03005	COG1388	LysM domain
NL113_RS03005	COG3584	3D domain protein
NL113_RS03015	COG0346	lactoylglutathione lyase activity
NL113_RS03020	COG0697	spore germination
NL113_RS03025	COG0583	DNA-binding transcription factor activity
NL113_RS03030	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NL113_RS03035	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NL113_RS03040	COG0583	DNA-binding transcription factor activity
NL113_RS03050	COG0110	maltose O-acetyltransferase activity
NL113_RS03070	COG1388	LysM domain
NL113_RS03075	COG2267	carboxylic ester hydrolase activity
NL113_RS03080	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NL113_RS03100	COG1902	pentaerythritol trinitrate reductase activity
NL113_RS03105	COG1522	sequence-specific DNA binding
NL113_RS03120	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NL113_RS03125	COG1073	alpha beta
NL113_RS03135	COG0457	Tetratricopeptide repeat
NL113_RS03170	COG4282	regulation of fungal-type cell wall biogenesis
NL113_RS03185	COG5505	Protein of unknown function (DUF819)
NL113_RS03190	COG0626	cystathionine gamma-synthase activity
NL113_RS03195	COG0626	cystathionine gamma-synthase activity
NL113_RS03200	COG2382	esterase
NL113_RS03205	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NL113_RS03210	COG2153	protein acetylation
NL113_RS03215	COG2246	polysaccharide biosynthetic process
NL113_RS03220	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NL113_RS03225	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NL113_RS03230	COG0586	Pfam SNARE associated Golgi protein
NL113_RS03240	COG0210	DNA helicase
NL113_RS03295	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NL113_RS03300	COG0351	phosphomethylpyrimidine kinase
NL113_RS03305	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NL113_RS03310	COG2022	thiamine diphosphate biosynthetic process
NL113_RS03315	COG2104	thiamine diphosphate biosynthetic process
NL113_RS03325	COG0352	thiamine-phosphate diphosphorylase activity
NL113_RS03330	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NL113_RS03335	COG0569	domain protein
NL113_RS03335	COG0475	glutathione-regulated potassium exporter activity
NL113_RS03340	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NL113_RS03345	COG0564	pseudouridine synthase activity
NL113_RS03350	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NL113_RS03355	COG2357	RelA SpoT domain protein
NL113_RS03365	COG4116	CYTH
NL113_RS03370	COG0741	lytic transglycosylase activity
NL113_RS03375	COG2346	COG2346, Truncated hemoglobins
NL113_RS03380	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NL113_RS03390	COG1164	Oligoendopeptidase f
NL113_RS03395	COG4469	Competence protein
NL113_RS03400	COG4862	establishment of competence for transformation
NL113_RS03410	COG0861	Integral membrane protein TerC family
NL113_RS03415	COG1393	Belongs to the ArsC family
NL113_RS03420	COG0456	acetyltransferase
NL113_RS03425	COG4608	Belongs to the ABC transporter superfamily
NL113_RS03430	COG0444	Belongs to the ABC transporter superfamily
NL113_RS03435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NL113_RS03440	COG0601	transmembrane transport
NL113_RS03445	COG4166	transmembrane transport
NL113_RS03450	COG0180	Tryptophanyl-tRNA synthetase
NL113_RS03460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NL113_RS03465	COG0601	transmembrane transport
NL113_RS03475	COG4608	Belongs to the ABC transporter superfamily
NL113_RS03480	COG0444	Belongs to the ABC transporter superfamily
NL113_RS03485	COG5504	Zn-dependent protease
NL113_RS03490	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NL113_RS03495	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NL113_RS03520	COG2267	carboxylic ester hydrolase activity
NL113_RS03535	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NL113_RS03540	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NL113_RS03545	COG0505	Belongs to the CarA family
NL113_RS03550	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NL113_RS03555	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NL113_RS03560	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NL113_RS03565	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NL113_RS03575	COG2151	metal-sulfur cluster biosynthetic enzyme
NL113_RS03580	COG1073	alpha beta
NL113_RS03585	COG0561	phosphatase activity
NL113_RS03600	COG0516	GMP reductase activity
NL113_RS03610	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NL113_RS03615	COG1307	EDD domain protein, DegV family
NL113_RS03630	COG2996	Protein conserved in bacteria
NL113_RS03635	COG1666	GTP binding
NL113_RS03640	COG0646	methionine synthase
NL113_RS03640	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NL113_RS03645	COG1410	methionine synthase
NL113_RS03645	COG0646	methionine synthase
NL113_RS03670	COG0076	glutamate decarboxylase activity
NL113_RS03680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NL113_RS03685	COG1279	arginine transmembrane transporter activity
NL113_RS03690	COG0673	inositol 2-dehydrogenase activity
NL113_RS03695	COG1609	Transcriptional regulator
NL113_RS03705	COG1917	Cupin 2, conserved barrel domain protein
NL113_RS03705	COG2207	Transcriptional regulator
NL113_RS03710	COG0534	Mate efflux family protein
NL113_RS03720	COG0367	asparagine synthase
NL113_RS03740	COG0179	Fumarylacetoacetate (FAA) hydrolase
NL113_RS03750	COG5337	Spore coat protein CotH
NL113_RS03795	COG0419	ATPase involved in DNA repair
NL113_RS03800	COG0420	3'-5' exonuclease activity
NL113_RS03805	COG1074	ATP-dependent DNA helicase activity
NL113_RS03810	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
NL113_RS03815	COG4149	molybdate abc transporter
NL113_RS03820	COG0725	ABC transporter, periplasmic molybdate-binding protein
NL113_RS03825	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
NL113_RS03830	COG0745	RESPONSE REGULATOR receiver
NL113_RS03835	COG5002	protein histidine kinase activity
NL113_RS03840	COG2720	vancomycin resistance protein
NL113_RS03850	COG0477	Major facilitator Superfamily
NL113_RS03850	COG2814	Major facilitator Superfamily
NL113_RS03855	COG0318	PFAM AMP-dependent synthetase and ligase
NL113_RS03860	COG3546	catalase activity
NL113_RS03875	COG3180	Ammonia monooxygenase
NL113_RS03880	COG0549	Belongs to the carbamate kinase family
NL113_RS03890	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NL113_RS03895	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NL113_RS03900	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
NL113_RS03905	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
NL113_RS03910	COG3257	ureidoglycine aminohydrolase activity
NL113_RS03915	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NL113_RS03920	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NL113_RS03930	COG2508	Transcriptional regulator
NL113_RS03945	COG3421	Type III restriction
NL113_RS03950	COG2189	Belongs to the N(4) N(6)-methyltransferase family
NL113_RS03955	COG2003	Belongs to the UPF0758 family
NL113_RS03965	COG0681	Belongs to the peptidase S26 family
NL113_RS03970	COG0398	Pfam SNARE associated Golgi protein
NL113_RS03980	COG4903	ComK protein
NL113_RS03990	COG1028	Short-chain dehydrogenase reductase Sdr
NL113_RS03995	COG0723	plastoquinol--plastocyanin reductase activity
NL113_RS03995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NL113_RS04000	COG0840	transmembrane signaling receptor activity
NL113_RS04010	COG0406	alpha-ribazole phosphatase activity
NL113_RS04015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NL113_RS04020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NL113_RS04025	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
NL113_RS04035	COG0501	Belongs to the peptidase M48B family
NL113_RS04050	COG1396	sequence-specific DNA binding
NL113_RS04060	COG0318	PFAM AMP-dependent synthetase and ligase
NL113_RS04070	COG0095	Lipoate-protein ligase
NL113_RS04075	COG1234	tRNA 3'-trailer cleavage
NL113_RS04085	COG1301	dicarboxylic acid transport
NL113_RS04095	COG1363	Peptidase, m42
NL113_RS04100	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NL113_RS04105	COG1511	domain protein
NL113_RS04110	COG1309	transcriptional regulator
NL113_RS04115	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NL113_RS04120	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NL113_RS04125	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NL113_RS04130	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NL113_RS04135	COG2329	Antibiotic biosynthesis monooxygenase
NL113_RS04175	COG5444	nuclease activity
NL113_RS04215	COG5434	Belongs to the glycosyl hydrolase 28 family
NL113_RS04220	COG1705	Flagellar rod assembly protein muramidase FlgJ
NL113_RS04230	COG3953	SLT domain
NL113_RS04230	COG5280	Phage tail tape measure protein TP901
NL113_RS04295	COG1802	Transcriptional regulator
NL113_RS04295	COG4626	Terminase
NL113_RS04425	COG1473	amidohydrolase
NL113_RS04435	COG4473	ABC transporter
NL113_RS04440	COG1131	(ABC) transporter
NL113_RS04445	COG0537	adenosine 5'-monophosphoramidase activity
NL113_RS04450	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NL113_RS04465	COG4980	gas vesicle protein
NL113_RS04470	COG1846	Transcriptional regulator
NL113_RS04500	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NL113_RS04510	COG3481	metal-dependent phosphohydrolase, HD sub domain
NL113_RS04515	COG4717	serine-type aminopeptidase activity
NL113_RS04520	COG0420	3'-5' exonuclease activity
NL113_RS04525	COG1668	transmembrane transport
NL113_RS04530	COG4152	abc transporter atp-binding protein
NL113_RS04545	COG1024	Enoyl-CoA hydratase
NL113_RS04555	COG0490	domain, Protein
NL113_RS04560	COG0475	glutathione-regulated potassium exporter activity
NL113_RS04575	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NL113_RS04580	COG0561	phosphatase activity
NL113_RS04585	COG3679	Belongs to the UPF0342 family
NL113_RS04590	COG4399	Belongs to the UPF0754 family
NL113_RS04595	COG0189	ligase activity
NL113_RS04600	COG0189	ligase activity
NL113_RS04610	COG2508	Transcriptional regulator
NL113_RS04615	COG3842	ATPase activity
NL113_RS04635	COG0702	epimerase
NL113_RS04640	COG1132	(ABC) transporter
NL113_RS04645	COG1132	(ABC) transporter
NL113_RS04650	COG0589	response to stress
NL113_RS04670	COG2017	converts alpha-aldose to the beta-anomer
NL113_RS04675	COG1757	Na H antiporter
NL113_RS04685	COG0726	polysaccharide deacetylase
NL113_RS04695	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NL113_RS04700	COG0668	transmembrane transport
NL113_RS04710	COG0584	glycerophosphoryl diester phosphodiesterase
NL113_RS04715	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NL113_RS04720	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NL113_RS04740	COG1253	flavin adenine dinucleotide binding
NL113_RS04745	COG0789	Transcriptional regulator
NL113_RS04750	COG1253	flavin adenine dinucleotide binding
NL113_RS04755	COG1309	transcriptional regulator
NL113_RS04765	COG0204	Acyl-transferase
NL113_RS04770	COG1595	DNA-templated transcription, initiation
NL113_RS04785	COG0456	acetyltransferase
NL113_RS04790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NL113_RS04795	COG2207	Transcriptional regulator
NL113_RS04795	COG3708	Transcriptional regulator
NL113_RS04805	COG0733	neurotransmitter:sodium symporter activity
NL113_RS04810	COG0531	amino acid
NL113_RS04820	COG0372	Belongs to the citrate synthase family
NL113_RS04825	COG0583	DNA-binding transcription factor activity
NL113_RS04830	COG0791	NLP P60 protein
NL113_RS04830	COG1388	LysM domain
NL113_RS04845	COG2719	SpoVR family
NL113_RS04850	COG1017	nitric oxide dioxygenase activity
NL113_RS04850	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NL113_RS04855	COG1959	2 iron, 2 sulfur cluster binding
NL113_RS04870	COG0431	NADPH-dependent FMN reductase
NL113_RS04875	COG2197	response regulator
NL113_RS04880	COG2203	Gaf domain
NL113_RS04880	COG4585	Histidine kinase
NL113_RS04900	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NL113_RS04905	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NL113_RS04910	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NL113_RS04915	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NL113_RS04920	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NL113_RS04925	COG0604	alcohol dehydrogenase
NL113_RS04930	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NL113_RS04935	COG0679	Auxin Efflux Carrier
NL113_RS04945	COG0488	(ABC) transporter
NL113_RS04950	COG3153	acetyltransferase
NL113_RS04950	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NL113_RS04955	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NL113_RS04960	COG0517	IMP dehydrogenase activity
NL113_RS04970	COG0564	pseudouridine synthase activity
NL113_RS04975	COG1174	glycine betaine transport
NL113_RS04980	COG1732	Glycine betaine
NL113_RS04985	COG1174	glycine betaine transport
NL113_RS04990	COG1125	glycine betaine transport
NL113_RS04990	COG0517	IMP dehydrogenase activity
NL113_RS04995	COG3764	Sortase (surface protein transpeptidase)
NL113_RS05000	COG4085	toxin activity
NL113_RS05000	COG1525	nuclease
NL113_RS05000	COG0737	Belongs to the 5'-nucleotidase family
NL113_RS05005	COG5002	protein histidine kinase activity
NL113_RS05010	COG5577	PFAM Coat F domain
NL113_RS05035	COG1823	symporter activity
NL113_RS05040	COG1464	Belongs to the NlpA lipoprotein family
NL113_RS05045	COG2011	ABC-type metal ion transport system permease component
NL113_RS05050	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NL113_RS05055	COG1278	Cold shock
NL113_RS05060	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NL113_RS05065	COG1131	(ABC) transporter
NL113_RS05070	COG1131	(ABC) transporter
NL113_RS05075	COG1725	Transcriptional regulator
NL113_RS05090	COG0655	NAD(P)H dehydrogenase (quinone) activity
NL113_RS05095	COG2814	Major facilitator Superfamily
NL113_RS05100	COG1566	PFAM secretion protein HlyD family protein
NL113_RS05105	COG2718	Belongs to the UPF0229 family
NL113_RS05110	COG2766	serine protein kinase
NL113_RS05120	COG1664	Polymer-forming cytoskeletal
NL113_RS05125	COG0789	Transcriptional regulator
NL113_RS05130	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NL113_RS05140	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NL113_RS05145	COG3382	B3 4 domain protein
NL113_RS05155	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NL113_RS05160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NL113_RS05165	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NL113_RS05170	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NL113_RS05175	COG1116	anion transmembrane transporter activity
NL113_RS05180	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NL113_RS05185	COG4326	sporulation control protein
NL113_RS05190	COG0710	3-dehydroquinate dehydratase activity
NL113_RS05200	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NL113_RS05310	COG0735	belongs to the Fur family
NL113_RS05315	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NL113_RS05320	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NL113_RS05325	COG4129	membrane
NL113_RS05330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NL113_RS05335	COG0601	transmembrane transport
NL113_RS05340	COG0747	negative chemotaxis
NL113_RS05345	COG4608	Belongs to the ABC transporter superfamily
NL113_RS05350	COG0444	Belongs to the ABC transporter superfamily
NL113_RS05355	COG1132	(ABC) transporter
NL113_RS05360	COG3557	Belongs to the UPF0374 family
NL113_RS05375	COG1028	Short-chain dehydrogenase reductase Sdr
NL113_RS05385	COG1194	a g-specific adenine glycosylase
NL113_RS05390	COG1988	membrane-bound metal-dependent
NL113_RS05395	COG4485	Bacterial membrane protein, YfhO
NL113_RS05405	COG0463	Glycosyl transferase, family 2
NL113_RS05410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NL113_RS05435	COG2137	regulation of response to DNA damage stimulus
NL113_RS05440	COG1090	epimerase
NL113_RS05460	COG0778	Nitroreductase
NL113_RS05465	COG0384	phenazine biosynthesis protein PhzF
NL113_RS05470	COG0392	lysyltransferase activity
NL113_RS05470	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NL113_RS05480	COG1051	belongs to the nudix hydrolase family
NL113_RS05485	COG2249	NAD(P)H dehydrogenase (quinone) activity
NL113_RS05490	COG2814	Major facilitator Superfamily
NL113_RS05495	COG1309	transcriptional regulator
NL113_RS05500	COG1653	transport
NL113_RS05505	COG1917	Cupin 2, conserved barrel domain protein
NL113_RS05505	COG2207	Transcriptional regulator
NL113_RS05510	COG3507	Belongs to the glycosyl hydrolase 43 family
NL113_RS05520	COG2514	catechol 2,3-dioxygenase activity
NL113_RS05525	COG2259	Doxx family
NL113_RS05530	COG1733	regulation of RNA biosynthetic process
NL113_RS05540	COG1263	PTS System
NL113_RS05540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NL113_RS05545	COG1737	Transcriptional regulator
NL113_RS05550	COG1486	melibiose metabolic process
NL113_RS05555	COG1742	UPF0060 membrane protein
NL113_RS05560	COG3284	Transcriptional regulator
NL113_RS05565	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NL113_RS05570	COG0508	dehydrogenase complex catalyzes the overall conversion of
NL113_RS05575	COG0022	dehydrogenase e1 component
NL113_RS05580	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NL113_RS05590	COG3711	transcriptional antiterminator
NL113_RS05595	COG1263	PTS System
NL113_RS05595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NL113_RS05600	COG0477	Major facilitator Superfamily
NL113_RS05610	COG4637	Psort location Cytoplasmic, score
NL113_RS05615	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NL113_RS05620	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NL113_RS05625	COG0598	Magnesium transport protein CorA
NL113_RS05640	COG0371	Dehydrogenase
NL113_RS05645	COG0726	polysaccharide deacetylase
NL113_RS05655	COG0535	radical SAM domain protein
NL113_RS05665	COG0387	Pfam Sodium calcium exchanger
NL113_RS05675	COG0477	Major facilitator Superfamily
NL113_RS05680	COG1295	ribonuclease BN
NL113_RS05685	COG4980	gas vesicle protein
NL113_RS05690	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NL113_RS05695	COG1115	amino acid carrier protein
NL113_RS05700	COG4840	Belongs to the UPF0435 family
NL113_RS05705	COG0693	protein deglycase activity
NL113_RS05710	COG0737	Belongs to the 5'-nucleotidase family
NL113_RS05715	COG0778	Nitroreductase
NL113_RS05720	COG1733	regulation of RNA biosynthetic process
NL113_RS05725	COG1073	alpha beta
NL113_RS05735	COG0673	inositol 2-dehydrogenase activity
NL113_RS05745	COG0463	Glycosyl transferase, family 2
NL113_RS05745	COG0457	Tetratricopeptide repeat
NL113_RS05750	COG0463	Glycosyl transferase, family 2
NL113_RS05765	COG2188	Transcriptional regulator
NL113_RS05770	COG0366	Alpha amylase catalytic
NL113_RS05775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NL113_RS05775	COG1263	PTS System
NL113_RS05780	COG1115	amino acid carrier protein
NL113_RS05790	COG1368	sulfuric ester hydrolase activity
NL113_RS05795	COG0024	Methionine aminopeptidase
NL113_RS05810	COG2258	MOSC domain
NL113_RS05815	COG1254	Belongs to the acylphosphatase family
NL113_RS05820	COG0640	Transcriptional regulator
NL113_RS05825	COG5658	integral membrane protein
NL113_RS05840	COG3858	chitin binding
NL113_RS05845	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NL113_RS05855	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NL113_RS05870	COG0471	metal ion transport
NL113_RS05890	COG0513	Belongs to the DEAD box helicase family
NL113_RS05895	COG0488	(ABC) transporter
NL113_RS05900	COG2814	Major facilitator Superfamily
NL113_RS05905	COG0789	Transcriptional regulator
NL113_RS05910	COG2124	cytochrome p450
NL113_RS05915	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NL113_RS05920	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NL113_RS05930	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NL113_RS05935	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
NL113_RS05940	COG0523	cobalamin synthesis protein
NL113_RS05955	COG1469	GTP cyclohydrolase I activity
NL113_RS05960	COG2814	Major facilitator Superfamily
NL113_RS05965	COG0640	Transcriptional regulator
NL113_RS05970	COG0488	(ABC) transporter
NL113_RS05975	COG0471	metal ion transport
NL113_RS05980	COG5444	nuclease activity
NL113_RS05985	COG0840	transmembrane signaling receptor activity
NL113_RS05990	COG1012	belongs to the aldehyde dehydrogenase family
NL113_RS05995	COG0583	DNA-binding transcription factor activity
NL113_RS06000	COG0281	malic enzyme
NL113_RS06005	COG0471	metal ion transport
NL113_RS06025	COG0217	transcriptional regulatory protein
NL113_RS06035	COG0697	spore germination
NL113_RS06040	COG3586	endonuclease activity
NL113_RS06045	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
NL113_RS06045	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NL113_RS06055	COG3711	transcriptional antiterminator
NL113_RS06060	COG2723	6-phospho-beta-galactosidase activity
NL113_RS06065	COG1263	PTS System
NL113_RS06065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NL113_RS06065	COG2190	(PTS) system
NL113_RS06090	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
NL113_RS06105	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NL113_RS06110	COG1597	lipid kinase activity
NL113_RS06115	COG1957	nucleoside hydrolase
NL113_RS06120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NL113_RS06125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NL113_RS06130	COG1309	transcriptional regulator
NL113_RS06135	COG1063	alcohol dehydrogenase
NL113_RS06145	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NL113_RS06150	COG0154	amidase activity
NL113_RS06155	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NL113_RS06160	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NL113_RS06170	COG1285	pathogenesis
NL113_RS06175	COG3457	Alanine racemase
NL113_RS06180	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NL113_RS06185	COG0626	cystathionine gamma-synthase activity
NL113_RS06190	COG1735	metal-dependent hydrolase with the TIM-barrel fold
NL113_RS06210	COG2188	Transcriptional regulator
NL113_RS06215	COG4851	CamS sex pheromone cAM373 precursor
NL113_RS06220	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NL113_RS06225	COG0210	DNA helicase
NL113_RS06230	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
NL113_RS06235	COG4496	protein, YerC YecD
NL113_RS06240	COG1470	cell adhesion involved in biofilm formation
NL113_RS06245	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NL113_RS06255	COG2124	cytochrome p450
NL113_RS06265	COG0151	Belongs to the GarS family
NL113_RS06270	COG0138	bifunctional purine biosynthesis protein purh
NL113_RS06275	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NL113_RS06280	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NL113_RS06285	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NL113_RS06290	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NL113_RS06295	COG0047	phosphoribosylformylglycinamidine synthase activity
NL113_RS06300	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NL113_RS06305	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NL113_RS06310	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NL113_RS06315	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NL113_RS06320	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NL113_RS06330	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
NL113_RS06345	COG2252	PERMEase
NL113_RS06350	COG0519	Catalyzes the synthesis of GMP from XMP
NL113_RS06350	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NL113_RS06355	COG1305	Transglutaminase-like
NL113_RS06360	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
NL113_RS06365	COG0714	Associated with various cellular activities
NL113_RS06370	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NL113_RS06380	COG2132	Multicopper oxidase
NL113_RS06390	COG0702	epimerase
NL113_RS06410	COG0823	Involved in the tonB-independent uptake of proteins
NL113_RS06415	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NL113_RS06420	COG3739	integral membrane protein
NL113_RS06425	COG3655	Transcriptional regulator
NL113_RS06450	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NL113_RS06455	COG0366	Alpha amylase catalytic
NL113_RS06460	COG1554	hydrolase, family 65, central catalytic
NL113_RS06465	COG5521	maltodextrose utilization protein MalA
NL113_RS06470	COG3833	ABC-type maltose transport systems, permease component
NL113_RS06475	COG1175	transmembrane transport
NL113_RS06480	COG2182	Extracellular solute-binding protein
NL113_RS06485	COG0366	Alpha amylase catalytic
NL113_RS06490	COG1609	Transcriptional regulator
NL113_RS06500	COG0726	polysaccharide deacetylase
NL113_RS06530	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NL113_RS06535	COG1280	lysine exporter protein (LysE YggA)
NL113_RS06540	COG1378	Sugar-specific transcriptional regulator TrmB
NL113_RS06550	COG0640	Transcriptional regulator
NL113_RS06565	COG2272	Belongs to the type-B carboxylesterase lipase family
NL113_RS06570	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
NL113_RS06575	COG3189	MarR family transcriptional regulator
NL113_RS06585	COG3848	Pyruvate phosphate dikinase
NL113_RS06585	COG0574	Belongs to the PEP-utilizing enzyme family
NL113_RS06590	COG1309	transcriptional regulator
NL113_RS06615	COG0402	S-adenosylhomocysteine deaminase activity
NL113_RS06620	COG5634	Uncharacterized conserved protein (DUF2278)
NL113_RS06625	COG0459	protein refolding
NL113_RS06630	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NL113_RS06635	COG1266	CAAX protease self-immunity
NL113_RS06645	COG0805	protein transport
NL113_RS06650	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NL113_RS06655	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NL113_RS06660	COG0315	cyclic pyranopterin monophosphate synthase activity
NL113_RS06665	COG0488	(ABC) transporter
NL113_RS06670	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NL113_RS06675	COG0456	acetyltransferase
NL113_RS06680	COG1214	PFAM Peptidase M22, glycoprotease
NL113_RS06685	COG0802	atpase or kinase
NL113_RS06690	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NL113_RS06730	COG2814	Major facilitator Superfamily
NL113_RS06735	COG3764	Sortase (surface protein transpeptidase)
NL113_RS06750	COG1979	alcohol dehydrogenase
NL113_RS06755	COG2814	Major facilitator Superfamily
NL113_RS06760	COG0494	nUDIX hydrolase
NL113_RS06765	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NL113_RS06765	COG2755	lipolytic protein G-D-S-L family
NL113_RS06775	COG1595	DNA-templated transcription, initiation
NL113_RS06780	COG5566	PFAM Mor transcription activator
NL113_RS06785	COG0596	Alpha beta hydrolase
NL113_RS06795	COG1309	transcriptional regulator
NL113_RS06820	COG1113	amino acid transport
NL113_RS06825	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NL113_RS06830	COG0778	Nitroreductase
NL113_RS06840	COG0583	DNA-binding transcription factor activity
NL113_RS06855	COG1114	Component of the transport system for branched-chain amino acids
NL113_RS06860	COG1309	transcriptional regulator
NL113_RS06865	COG2814	Major facilitator Superfamily
NL113_RS06870	COG2249	NAD(P)H dehydrogenase (quinone) activity
NL113_RS06875	COG1733	regulation of RNA biosynthetic process
NL113_RS06880	COG0789	Transcriptional regulator
NL113_RS06880	COG4978	Transcriptional regulator
NL113_RS06885	COG2814	Major facilitator Superfamily
NL113_RS06900	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NL113_RS06915	COG1733	regulation of RNA biosynthetic process
NL113_RS06925	COG0457	Tetratricopeptide repeat
NL113_RS06935	COG4124	Belongs to the glycosyl hydrolase 26 family
NL113_RS06940	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
NL113_RS06955	COG0477	Major facilitator Superfamily
NL113_RS06960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NL113_RS06965	COG1278	Cold shock
NL113_RS06970	COG3239	Fatty acid desaturase
NL113_RS06990	COG0457	Tetratricopeptide repeat
NL113_RS07035	COG3091	SprT-like family
NL113_RS07045	COG1033	growth of symbiont in host cell
NL113_RS07045	COG2409	Drug exporters of the RND superfamily
NL113_RS07050	COG1309	transcriptional regulator
NL113_RS07055	COG2183	response to ionizing radiation
NL113_RS07060	COG2208	phosphoserine phosphatase activity
NL113_RS07065	COG1191	sigma factor activity
NL113_RS07080	COG2208	phosphoserine phosphatase activity
NL113_RS07085	COG2172	sigma factor antagonist activity
NL113_RS07090	COG1366	Belongs to the anti-sigma-factor antagonist family
NL113_RS07095	COG1366	Belongs to the anti-sigma-factor antagonist family
NL113_RS07100	COG2337	Toxic component of a toxin-antitoxin (TA) module
NL113_RS07105	COG0864	Transcriptional regulator
NL113_RS07110	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NL113_RS07115	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
NL113_RS07120	COG0705	Rhomboid family
NL113_RS07125	COG3428	Bacterial PH domain
NL113_RS07130	COG3402	PFAM membrane-flanked domain
NL113_RS07135	COG0513	Belongs to the DEAD box helicase family
NL113_RS07145	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NL113_RS07150	COG1181	Belongs to the D-alanine--D-alanine ligase family
NL113_RS07155	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NL113_RS07170	COG1960	acyl-CoA dehydrogenase activity
NL113_RS07180	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NL113_RS07185	COG1131	(ABC) transporter
NL113_RS07190	COG1301	dicarboxylic acid transport
NL113_RS07195	COG0628	permease
NL113_RS07215	COG2217	Heavy metal translocating P-type atpase
NL113_RS07225	COG1819	glycosyl
NL113_RS07230	COG1027	Aspartate ammonia-lyase
NL113_RS07235	COG2261	transglycosylase associated protein
NL113_RS07240	COG1914	H( )-stimulated, divalent metal cation uptake system
NL113_RS07245	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NL113_RS07255	COG1028	Short-chain dehydrogenase reductase Sdr
NL113_RS07265	COG0028	Belongs to the TPP enzyme family
NL113_RS07270	COG0531	amino acid
NL113_RS07280	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NL113_RS07280	COG0551	DNA topoisomerase type I activity
NL113_RS07285	COG1522	sequence-specific DNA binding
NL113_RS07295	COG2814	Major facilitator Superfamily
NL113_RS07315	COG3871	stress protein (general stress protein 26)
NL113_RS07320	COG1917	Cupin 2, conserved barrel domain protein
NL113_RS07325	COG1028	Short-chain dehydrogenase reductase Sdr
NL113_RS07330	COG3711	transcriptional antiterminator
NL113_RS07335	COG0246	Mannitol dehydrogenase
NL113_RS07340	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NL113_RS07345	COG2213	PTS system mannitol-specific
NL113_RS07350	COG2755	lipolytic protein G-D-S-L family
NL113_RS07355	COG1414	Transcriptional regulator
NL113_RS07360	COG1984	allophanate hydrolase subunit 2
NL113_RS07365	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NL113_RS07370	COG4336	lyase activity
NL113_RS07375	COG1914	H( )-stimulated, divalent metal cation uptake system
NL113_RS07380	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NL113_RS07385	COG0561	phosphatase activity
NL113_RS07400	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NL113_RS07415	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NL113_RS07430	COG0471	metal ion transport
NL113_RS07435	COG1802	Transcriptional regulator
NL113_RS07445	COG1587	Uroporphyrinogen-III synthase
NL113_RS07445	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NL113_RS07455	COG2146	nitrite reductase [NAD(P)H] activity
NL113_RS07460	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NL113_RS07465	COG0243	molybdopterin cofactor binding
NL113_RS07470	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NL113_RS07480	COG1349	DNA-binding transcription factor activity
NL113_RS07485	COG1276	copper resistance
NL113_RS07485	COG2372	response to copper ion
NL113_RS07490	COG4549	nuclear export factor GLE1
NL113_RS07495	COG0697	spore germination
NL113_RS07500	COG1012	belongs to the aldehyde dehydrogenase family
NL113_RS07505	COG0531	amino acid
NL113_RS07510	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NL113_RS07515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NL113_RS07520	COG0640	Transcriptional regulator
NL113_RS07525	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
NL113_RS07530	COG0778	Nitroreductase
NL113_RS07540	COG1309	transcriptional regulator
NL113_RS07545	COG2814	Major facilitator Superfamily
NL113_RS07550	COG4607	ABC-type enterochelin transport system periplasmic component
NL113_RS07555	COG4604	ABC transporter, ATP-binding protein
NL113_RS07560	COG4605	iron ion homeostasis
NL113_RS07565	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NL113_RS07570	COG0527	aspartate kinase activity
NL113_RS07575	COG5278	phosphoserine phosphatase activity
NL113_RS07575	COG0840	transmembrane signaling receptor activity
NL113_RS07580	COG5002	protein histidine kinase activity
NL113_RS07580	COG3850	Histidine kinase
NL113_RS07585	COG0745	RESPONSE REGULATOR receiver
NL113_RS07590	COG0577	efflux transmembrane transporter activity
NL113_RS07595	COG1136	(ABC) transporter
NL113_RS07600	COG0789	Transcriptional regulator
NL113_RS07605	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
NL113_RS07625	COG5434	Belongs to the glycosyl hydrolase 28 family
NL113_RS07630	COG3104	oligopeptide transport
NL113_RS07635	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
NL113_RS07640	COG1874	Beta-galactosidase
NL113_RS07645	COG1846	Transcriptional regulator
NL113_RS07645	COG0456	acetyltransferase
NL113_RS07650	COG2271	Major facilitator Superfamily
NL113_RS07655	COG4214	carbohydrate transport
NL113_RS07665	COG4213	ABC transporter substrate-binding protein
NL113_RS07670	COG2207	Transcriptional regulator
NL113_RS07670	COG4753	response regulator
NL113_RS07675	COG2972	Histidine kinase
NL113_RS07695	COG5444	nuclease activity
NL113_RS07720	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
NL113_RS07725	COG0163	prenyltransferase activity
NL113_RS07730	COG0583	DNA-binding transcription factor activity
NL113_RS07735	COG2808	Putative FMN-binding domain
NL113_RS07740	COG0456	acetyltransferase
NL113_RS07745	COG1846	Transcriptional regulator
NL113_RS07750	COG2364	Membrane
NL113_RS07755	COG0010	Belongs to the arginase family
NL113_RS07760	COG0833	amino acid
NL113_RS07765	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NL113_RS07770	COG3829	transcription factor binding
NL113_RS07775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NL113_RS07780	COG0765	amino acid transport
NL113_RS07785	COG1126	abc transporter atp-binding protein
NL113_RS07810	COG2364	Membrane
NL113_RS07835	COG2207	Transcriptional regulator
NL113_RS07835	COG3708	Transcriptional regulator
NL113_RS07840	COG3708	Transcriptional regulator
NL113_RS07840	COG2207	Transcriptional regulator
NL113_RS07845	COG2819	hydrolase of the alpha beta superfamily
NL113_RS07855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NL113_RS07860	COG0697	spore germination
NL113_RS07865	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
NL113_RS07870	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NL113_RS07875	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NL113_RS07880	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NL113_RS07885	COG2814	Major facilitator Superfamily
NL113_RS07900	COG1176	ABC-type spermidine putrescine transport system, permease component I
NL113_RS07910	COG3842	ATPase activity
NL113_RS07930	COG5444	nuclease activity
NL113_RS07950	COG2723	6-phospho-beta-galactosidase activity
NL113_RS07960	COG1120	ATPase activity
NL113_RS07965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NL113_RS07970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NL113_RS07975	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
NL113_RS07985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NL113_RS07990	COG0765	amino acid transport
NL113_RS08015	COG3458	cephalosporin-C deacetylase activity
NL113_RS08020	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NL113_RS08025	COG0701	Predicted permease
NL113_RS08030	COG3689	TIGRFAM TIGR03943 family protein
NL113_RS08035	COG2508	Transcriptional regulator
NL113_RS08040	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NL113_RS08045	COG1012	belongs to the aldehyde dehydrogenase family
NL113_RS08050	COG0506	proline dehydrogenase activity
NL113_RS08055	COG3541	Predicted nucleotidyltransferase
NL113_RS08065	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NL113_RS08070	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NL113_RS08075	COG1113	amino acid transport
NL113_RS08080	COG1280	lysine exporter protein (LysE YggA)
NL113_RS08085	COG1620	l-lactate permease
NL113_RS08090	COG0039	L-malate dehydrogenase activity
NL113_RS08100	COG1288	antiporter activity
NL113_RS08105	COG1473	amidohydrolase
NL113_RS08110	COG2113	Glycine betaine
NL113_RS08115	COG4176	ABC-type proline glycine betaine transport system permease component
NL113_RS08120	COG4175	Glycine betaine
NL113_RS08120	COG0517	IMP dehydrogenase activity
NL113_RS08125	COG3853	Toxic anion resistance protein (TelA)
NL113_RS08160	COG0861	Integral membrane protein TerC family
NL113_RS08165	COG2310	stress, protein
NL113_RS08170	COG2310	stress, protein
NL113_RS08175	COG2310	stress, protein
NL113_RS08185	COG1309	transcriptional regulator
NL113_RS08190	COG1131	(ABC) transporter
NL113_RS08200	COG0791	NLP P60 protein
NL113_RS08200	COG3883	PFAM NLP P60 protein
NL113_RS08205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NL113_RS08210	COG3773	Cell wall hydrolase
NL113_RS08220	COG1595	DNA-templated transcription, initiation
NL113_RS08230	COG1028	Short-chain dehydrogenase reductase Sdr
NL113_RS08235	COG3591	Belongs to the peptidase S1B family
NL113_RS08240	COG0277	FAD linked oxidase domain protein
NL113_RS08245	COG0247	lactate metabolic process
NL113_RS08255	COG2261	transglycosylase associated protein
NL113_RS08260	COG1164	Oligoendopeptidase f
NL113_RS08270	COG0456	acetyltransferase
NL113_RS08275	COG0252	asparaginase activity
NL113_RS08285	COG1288	antiporter activity
NL113_RS08295	COG4106	trans-aconitate 2-methyltransferase activity
NL113_RS08300	COG1028	Short-chain dehydrogenase reductase Sdr
NL113_RS08305	COG1942	4-Oxalocrotonate Tautomerase
NL113_RS08310	COG0583	DNA-binding transcription factor activity
NL113_RS08315	COG1405	negative regulation of cell septum assembly
NL113_RS08315	COG3012	SEC-C Motif Domain Protein
NL113_RS08320	COG1714	RDD family
NL113_RS08325	COG0697	spore germination
NL113_RS08340	COG0789	Transcriptional regulator
NL113_RS08365	COG0318	PFAM AMP-dependent synthetase and ligase
NL113_RS08370	COG1846	Transcriptional regulator
NL113_RS08375	COG3173	Aminoglycoside phosphotransferase
NL113_RS08405	COG1131	(ABC) transporter
NL113_RS08410	COG2205	protein histidine kinase activity
NL113_RS08415	COG0745	RESPONSE REGULATOR receiver
NL113_RS08435	COG2721	sulfolactate sulfo-lyase activity
NL113_RS08440	COG2186	Transcriptional regulator
NL113_RS08445	COG4948	Mandelate Racemase Muconate Lactonizing
NL113_RS08450	COG2271	Major facilitator Superfamily
NL113_RS08455	COG1012	belongs to the aldehyde dehydrogenase family
NL113_RS08460	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NL113_RS08465	COG0805	protein transport
NL113_RS08470	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NL113_RS08475	COG3540	Alkaline phosphatase
NL113_RS08485	COG0784	Response regulator, receiver
NL113_RS08490	COG4191	Histidine kinase
NL113_RS08495	COG2066	Belongs to the glutaminase family
NL113_RS08500	COG1115	amino acid carrier protein
NL113_RS08510	COG2205	protein histidine kinase activity
NL113_RS08520	COG0531	amino acid
NL113_RS08535	COG1263	PTS System
NL113_RS08535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NL113_RS08540	COG3394	polysaccharide catabolic process
NL113_RS08545	COG2188	Transcriptional regulator
NL113_RS08550	COG0363	glucosamine-6-phosphate deaminase activity
NL113_RS08565	COG4257	antibiotic catabolic process
NL113_RS08575	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NL113_RS08580	COG0371	Dehydrogenase
NL113_RS08600	COG1917	Cupin 2, conserved barrel domain protein
NL113_RS08600	COG2207	Transcriptional regulator
NL113_RS08605	COG0697	spore germination
NL113_RS08615	COG3409	Peptidoglycan-binding domain 1 protein
NL113_RS08630	COG4682	membrane
NL113_RS08635	COG1283	sodium-dependent phosphate transmembrane transporter activity
NL113_RS08645	COG0730	response to heat
NL113_RS08650	COG1802	Transcriptional regulator
NL113_RS08655	COG0778	Nitroreductase
NL113_RS08665	COG2226	methyltransferase
NL113_RS08690	COG2211	Major facilitator Superfamily
NL113_RS08695	COG0596	Alpha beta hydrolase
NL113_RS08700	COG1733	regulation of RNA biosynthetic process
NL113_RS08710	COG1331	Highly conserved protein containing a thioredoxin domain
NL113_RS08720	COG1917	Cupin 2, conserved barrel domain protein
NL113_RS08720	COG2207	Transcriptional regulator
NL113_RS08735	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
NL113_RS08745	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NL113_RS08790	COG1113	amino acid transport
NL113_RS08795	COG1011	Hydrolase
NL113_RS08815	COG2312	Erythromycin esterase
NL113_RS08825	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NL113_RS08835	COG1131	(ABC) transporter
NL113_RS08850	COG1132	(ABC) transporter
NL113_RS08875	COG1131	(ABC) transporter
NL113_RS08910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NL113_RS08915	COG1309	transcriptional regulator
NL113_RS08920	COG2814	Major facilitator Superfamily
NL113_RS08925	COG0640	Transcriptional regulator
NL113_RS08935	COG1725	Transcriptional regulator
NL113_RS08960	COG2723	6-phospho-beta-galactosidase activity
NL113_RS08965	COG2190	(PTS) system
NL113_RS08975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NL113_RS08975	COG2190	(PTS) system
NL113_RS08975	COG1263	PTS System
NL113_RS08980	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NL113_RS08985	COG3958	Transketolase
NL113_RS08990	COG3959	Transketolase, thiamine diphosphate binding domain
NL113_RS09000	COG1609	Transcriptional regulator
NL113_RS09005	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NL113_RS09010	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NL113_RS09015	COG4856	YbbR-like protein
NL113_RS09020	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NL113_RS09025	COG5662	AntiSigma factor
NL113_RS09030	COG1595	DNA-templated transcription, initiation
NL113_RS09065	COG1683	Conserved Protein
NL113_RS09070	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NL113_RS09075	COG1737	Transcriptional regulator
NL113_RS09080	COG1263	PTS System
NL113_RS09080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NL113_RS09085	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NL113_RS09090	COG1472	Belongs to the glycosyl hydrolase 3 family
NL113_RS09095	COG3876	Protein conserved in bacteria
NL113_RS09100	COG0385	Bile acid
NL113_RS09110	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NL113_RS09125	COG5444	nuclease activity
NL113_RS09130	COG0457	Tetratricopeptide repeat
NL113_RS09175	COG0726	polysaccharide deacetylase
NL113_RS09180	COG2194	sulfuric ester hydrolase activity
NL113_RS09190	COG0489	protein tyrosine kinase activity
NL113_RS09195	COG0860	N-Acetylmuramoyl-L-alanine amidase
NL113_RS09215	COG3290	protein histidine kinase activity
NL113_RS09245	COG1131	(ABC) transporter
NL113_RS09265	COG2318	DinB family
NL113_RS09270	COG2318	DinB family
NL113_RS09275	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NL113_RS09280	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NL113_RS09285	COG0101	tRNA pseudouridine synthase activity
NL113_RS09290	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NL113_RS09295	COG1122	ATPase activity
NL113_RS09300	COG1122	ATPase activity
NL113_RS09305	COG0203	ribosomal protein L17
NL113_RS09310	COG0202	RNA polymerase activity
NL113_RS09315	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NL113_RS09320	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NL113_RS09325	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NL113_RS09330	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NL113_RS09335	COG2163	COG2163 Ribosomal protein L14E L6E L27E
NL113_RS09340	COG0024	Methionine aminopeptidase
NL113_RS09345	COG0563	adenylate kinase activity
NL113_RS09350	COG0201	protein transport
NL113_RS09355	COG0200	Binds to the 23S rRNA
NL113_RS09365	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NL113_RS09370	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NL113_RS09375	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NL113_RS09380	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NL113_RS09385	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NL113_RS09390	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NL113_RS09395	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NL113_RS09400	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NL113_RS09405	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NL113_RS09410	COG0255	Belongs to the universal ribosomal protein uL29 family
NL113_RS09415	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NL113_RS09420	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NL113_RS09425	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NL113_RS09430	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NL113_RS09435	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NL113_RS09440	COG0089	rRNA binding
NL113_RS09445	COG0088	Forms part of the polypeptide exit tunnel
NL113_RS09450	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NL113_RS09460	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NL113_RS09465	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NL113_RS09470	COG0049	tRNA binding
NL113_RS09475	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NL113_RS09480	COG1358	cellular component organization or biogenesis
NL113_RS09485	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NL113_RS09490	COG0085	RNA polymerase activity
NL113_RS09495	COG2813	Specifically methylates the guanine in position
NL113_RS09500	COG0222	ribosome binding
NL113_RS09505	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NL113_RS09510	COG0081	regulation of translation
NL113_RS09515	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NL113_RS09520	COG0250	Participates in transcription elongation, termination and antitermination
NL113_RS09530	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NL113_RS09540	COG3688	RNA-binding protein containing a PIN domain
NL113_RS09545	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NL113_RS09555	COG0215	cysteine-tRNA ligase activity
NL113_RS09560	COG1045	serine acetyltransferase
NL113_RS09565	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NL113_RS09570	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NL113_RS09575	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NL113_RS09580	COG4956	integral membrane protein (PIN domain superfamily)
NL113_RS09585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NL113_RS09590	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NL113_RS09595	COG0542	response to heat
NL113_RS09600	COG3869	Catalyzes the specific phosphorylation of arginine residues in
NL113_RS09605	COG3880	PFAM UvrB UvrC protein
NL113_RS09610	COG4463	regulation of RNA biosynthetic process
NL113_RS09690	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NL113_RS09695	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NL113_RS09700	COG1396	sequence-specific DNA binding
NL113_RS09705	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NL113_RS09710	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NL113_RS09715	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NL113_RS09720	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NL113_RS09725	COG0512	Glutamine amidotransferase of anthranilate synthase
NL113_RS09730	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NL113_RS09735	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NL113_RS09745	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NL113_RS09750	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NL113_RS09755	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NL113_RS09760	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NL113_RS09765	COG0037	tRNA processing
NL113_RS09770	COG0515	serine threonine protein kinase
NL113_RS09775	COG2304	oxidoreductase activity
NL113_RS09780	COG2208	phosphoserine phosphatase activity
NL113_RS09795	COG1098	S1 RNA binding domain
NL113_RS09800	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NL113_RS09815	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NL113_RS09820	COG3956	TIGRFAM MazG family protein
NL113_RS09825	COG2244	polysaccharide biosynthetic process
NL113_RS09830	COG2002	toxin-antitoxin pair type II binding
NL113_RS09835	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NL113_RS09845	COG0193	aminoacyl-tRNA hydrolase activity
NL113_RS09850	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NL113_RS09855	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NL113_RS09860	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NL113_RS09865	COG2088	sporulation resulting in formation of a cellular spore
NL113_RS09870	COG0251	oxidation-reduction process
NL113_RS09875	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NL113_RS09880	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NL113_RS09890	COG4466	Protein conserved in bacteria
NL113_RS09900	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NL113_RS09905	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NL113_RS09910	COG3583	domain protein
NL113_RS09910	COG3584	3D domain protein
NL113_RS09915	COG0084	hydrolase, TatD family'
NL113_RS09920	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NL113_RS09920	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NL113_RS09925	COG2002	toxin-antitoxin pair type II binding
NL113_RS09930	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NL113_RS09935	COG2827	Endonuclease containing a URI domain
NL113_RS09940	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NL113_RS09945	COG4467	Involved in initiation control of chromosome replication
NL113_RS09950	COG1774	PSP1 C-terminal conserved region
NL113_RS09955	COG0470	DNA polymerase III
NL113_RS09960	COG1728	Protein conserved in bacteria
NL113_RS09965	COG3870	Protein conserved in bacteria
NL113_RS09970	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NL113_RS09975	COG1982	Orn Lys Arg decarboxylase major
NL113_RS09980	COG3853	Toxic anion resistance protein (TelA)
NL113_RS09985	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
NL113_RS10030	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NL113_RS10035	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NL113_RS10040	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NL113_RS10050	COG0590	tRNA wobble adenosine to inosine editing
NL113_RS10055	COG1335	isochorismatase
NL113_RS10060	COG1388	LysM domain
NL113_RS10060	COG3858	chitin binding
NL113_RS10065	COG1428	Deoxynucleoside kinase
NL113_RS10070	COG1428	Deoxynucleoside kinase
NL113_RS10085	COG3835	regulator
NL113_RS10090	COG2610	gluconate transmembrane transporter activity
NL113_RS10095	COG1929	Belongs to the glycerate kinase type-1 family
NL113_RS10100	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NL113_RS10105	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NL113_RS10110	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NL113_RS10115	COG1686	Belongs to the peptidase S11 family
NL113_RS10120	COG0516	GMP reductase activity
NL113_RS10120	COG0517	IMP dehydrogenase activity
NL113_RS10155	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NL113_RS10160	COG0187	DNA topoisomerase II activity
NL113_RS10170	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NL113_RS10175	COG2501	S4 domain
NL113_RS10180	COG0592	DNA-directed DNA polymerase activity
NL113_RS10185	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NL113_RS10200	COG0594	ribonuclease P activity
NL113_RS10205	COG0706	membrane insertase activity
NL113_RS10210	COG1847	R3H domain protein
NL113_RS10215	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NL113_RS10220	COG0445	tRNA wobble uridine modification
NL113_RS10225	COG0357	Ribosomal RNA small subunit methyltransferase G
NL113_RS10230	COG1475	DNA binding
NL113_RS10240	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NL113_RS10245	COG1192	Involved in chromosome partitioning
NL113_RS10250	COG1475	DNA binding
NL113_RS10260	COG3949	Membrane
NL113_RS10265	COG4481	Protein conserved in bacteria
NL113_RS10270	COG0012	GTP binding
NL113_RS10275	COG0360	Binds together with S18 to 16S ribosomal RNA
NL113_RS10280	COG0629	single-stranded DNA binding
NL113_RS10285	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NL113_RS10290	COG2271	Major facilitator Superfamily
NL113_RS10295	COG0659	secondary active sulfate transmembrane transporter activity
NL113_RS10300	COG5577	PFAM Coat F domain
NL113_RS10310	COG4241	membrane
NL113_RS10315	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
NL113_RS10320	COG0359	binds to the 23S rRNA
NL113_RS10325	COG1263	PTS System
NL113_RS10325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NL113_RS10330	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NL113_RS10335	COG2188	Transcriptional regulator
NL113_RS10340	COG0363	glucosamine-6-phosphate deaminase activity
NL113_RS10345	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NL113_RS10350	COG2807	transmembrane transport
NL113_RS10355	COG3093	addiction module antidote protein HigA
NL113_RS10370	COG0305	Participates in initiation and elongation during chromosome replication
NL113_RS10380	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NL113_RS10405	COG0745	RESPONSE REGULATOR receiver
NL113_RS10410	COG5002	protein histidine kinase activity
NL113_RS10415	COG4863	YycH protein
NL113_RS10420	COG4853	Protein conserved in bacteria
NL113_RS10425	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NL113_RS10430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NL113_RS10445	COG0456	acetyltransferase
NL113_RS10460	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NL113_RS10490	COG2197	response regulator
NL113_RS10495	COG4585	Histidine kinase
NL113_RS10500	COG0842	Transport permease protein
NL113_RS10505	COG1131	(ABC) transporter
NL113_RS10520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NL113_RS10525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NL113_RS10545	COG3634	alkyl hydroperoxide reductase activity
NL113_RS10550	COG0450	alkyl hydroperoxide reductase
NL113_RS10555	COG1012	belongs to the aldehyde dehydrogenase family
NL113_RS10555	COG1454	alcohol dehydrogenase
NL113_RS10560	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NL113_RS10565	COG2610	gluconate transmembrane transporter activity
NL113_RS10585	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NL113_RS10595	COG1940	carbohydrate kinase activity
NL113_RS10600	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
NL113_RS10605	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NL113_RS10610	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NL113_RS10615	COG1609	Transcriptional regulator
NL113_RS10620	COG2182	Extracellular solute-binding protein
NL113_RS10625	COG1175	transmembrane transport
NL113_RS10630	COG3833	ABC-type maltose transport systems, permease component
NL113_RS10635	COG1874	Beta-galactosidase
NL113_RS10640	COG3867	Arabinogalactan endo-beta-1,4-galactanase
NL113_RS10645	COG0686	Belongs to the AlaDH PNT family
NL113_RS10650	COG1115	amino acid carrier protein
NL113_RS10655	COG0840	transmembrane signaling receptor activity
NL113_RS10655	COG5278	phosphoserine phosphatase activity
NL113_RS10665	COG0745	RESPONSE REGULATOR receiver
NL113_RS10670	COG2205	protein histidine kinase activity
NL113_RS10675	COG1136	(ABC) transporter
NL113_RS10680	COG0577	efflux transmembrane transporter activity
NL113_RS10685	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
NL113_RS10710	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NL113_RS10730	COG0561	phosphatase activity
NL113_RS10735	COG0488	(ABC) transporter
NL113_RS10740	COG0326	Molecular chaperone. Has ATPase activity
NL113_RS10745	COG2271	Major facilitator Superfamily
NL113_RS10750	COG0584	glycerophosphoryl diester phosphodiesterase
NL113_RS10755	COG0667	Aldo Keto reductase
NL113_RS10760	COG1349	DNA-binding transcription factor activity
NL113_RS10765	COG1012	belongs to the aldehyde dehydrogenase family
NL113_RS10770	COG3718	enzyme involved in inositol metabolism
NL113_RS10775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NL113_RS10780	COG3962	Belongs to the TPP enzyme family
NL113_RS10785	COG1082	Xylose isomerase domain protein TIM barrel
NL113_RS10790	COG2814	Major facilitator Superfamily
NL113_RS10800	COG1082	Xylose isomerase domain protein TIM barrel
NL113_RS10805	COG1082	Xylose isomerase domain protein TIM barrel
NL113_RS10810	COG0191	fructose-bisphosphate aldolase activity
NL113_RS10820	COG1181	Belongs to the D-alanine--D-alanine ligase family
NL113_RS10835	COG3977	Valine--pyruvate aminotransferase
NL113_RS10845	COG1215	transferase activity, transferring glycosyl groups
NL113_RS10855	COG3706	GGDEF domain
NL113_RS10860	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
NL113_RS10870	COG0457	Tetratricopeptide repeat
NL113_RS10875	COG2390	Transcriptional regulator
NL113_RS10880	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NL113_RS10885	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NL113_RS10890	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
NL113_RS10920	COG0513	Belongs to the DEAD box helicase family
NL113_RS10925	COG3507	Belongs to the glycosyl hydrolase 43 family
NL113_RS10935	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
NL113_RS10945	COG1263	PTS System
NL113_RS10945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NL113_RS10945	COG2190	(PTS) system
NL113_RS10950	COG2723	6-phospho-beta-galactosidase activity
NL113_RS10955	COG0745	RESPONSE REGULATOR receiver
NL113_RS10960	COG2205	protein histidine kinase activity
NL113_RS10965	COG1136	(ABC) transporter
NL113_RS10970	COG0577	efflux transmembrane transporter activity
NL113_RS10975	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NL113_RS10985	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NL113_RS10990	COG2224	Isocitrate lyase
NL113_RS10995	COG0561	phosphatase activity
NL113_RS11000	COG3775	system Galactitol-specific IIC component
NL113_RS11015	COG1349	DNA-binding transcription factor activity
NL113_RS11020	COG0698	ribose 5-phosphate isomerase
NL113_RS11025	COG0698	ribose 5-phosphate isomerase
NL113_RS11030	COG1105	Belongs to the carbohydrate kinase PfkB family
NL113_RS11035	COG3684	Belongs to the aldolase LacD family
NL113_RS11050	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NL113_RS11055	COG4721	ABC-type cobalt transport system, permease component
NL113_RS11060	COG1122	ATPase activity
NL113_RS11065	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NL113_RS11070	COG3711	transcriptional antiterminator
NL113_RS11075	COG2190	(PTS) system
NL113_RS11075	COG1263	PTS System
NL113_RS11075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NL113_RS11080	COG2723	6-phospho-beta-galactosidase activity
NL113_RS11085	COG2851	Citrate transporter
NL113_RS11090	COG0693	protein deglycase activity
NL113_RS11090	COG0753	catalase activity
NL113_RS11095	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NL113_RS11100	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NL113_RS11105	COG0463	Glycosyl transferase, family 2
NL113_RS11110	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NL113_RS11115	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NL113_RS11130	COG1609	Transcriptional regulator
NL113_RS11140	COG1175	transmembrane transport
NL113_RS11145	COG0395	ABC-type sugar transport system, permease component
NL113_RS11165	COG2195	Cleaves the N-terminal amino acid of tripeptides
NL113_RS11175	COG1595	DNA-templated transcription, initiation
NL113_RS11185	COG2205	protein histidine kinase activity
NL113_RS11190	COG0745	RESPONSE REGULATOR receiver
NL113_RS11210	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NL113_RS11215	COG2723	6-phospho-beta-galactosidase activity
NL113_RS11225	COG0549	Belongs to the carbamate kinase family
NL113_RS11235	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NL113_RS11240	COG2235	arginine
NL113_RS11245	COG1438	arginine binding
NL113_RS11250	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NL113_RS11260	COG1368	sulfuric ester hydrolase activity
NL113_RS11270	COG5444	nuclease activity
NL113_RS11290	COG0584	glycerophosphoryl diester phosphodiesterase
NL113_RS11295	COG3493	citrate carrier protein
NL113_RS11315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NL113_RS11320	COG0726	polysaccharide deacetylase
NL113_RS11335	COG5294	Protein conserved in bacteria
NL113_RS11340	COG0577	efflux transmembrane transporter activity
NL113_RS11345	COG1136	(ABC) transporter
NL113_RS11355	COG2205	protein histidine kinase activity
NL113_RS11360	COG0745	RESPONSE REGULATOR receiver
NL113_RS11365	COG2706	6-phosphogluconolactonase activity
NL113_RS11370	COG1396	sequence-specific DNA binding
NL113_RS11375	COG0252	asparaginase activity
NL113_RS11380	COG1027	Aspartate ammonia-lyase
NL113_RS11385	COG1757	Na H antiporter
NL113_RS11390	COG0281	malic enzyme
NL113_RS11400	COG2116	formate transmembrane transporter activity
NL113_RS11405	COG3001	Fructosamine kinase
NL113_RS11410	COG1271	oxidase subunit
NL113_RS11415	COG1294	oxidase, subunit
NL113_RS11420	COG4988	ABC transporter
NL113_RS11425	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NL113_RS11430	COG2311	Membrane
NL113_RS11435	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NL113_RS11445	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NL113_RS11455	COG0753	catalase activity
NL113_RS11460	COG0753	catalase activity
NL113_RS11465	COG2814	Major facilitator Superfamily
NL113_RS11470	COG1595	DNA-templated transcription, initiation
NL113_RS11490	COG1131	(ABC) transporter
NL113_RS11495	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NL113_RS11500	COG2814	Major facilitator Superfamily
NL113_RS11510	COG2755	lipolytic protein G-D-S-L family
NL113_RS11515	COG1132	(ABC) transporter
NL113_RS11530	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NL113_RS11535	COG2079	MmgE PrpD family protein
NL113_RS11540	COG0372	Belongs to the citrate synthase family
NL113_RS11545	COG2186	Transcriptional regulator
NL113_RS11555	COG1086	Polysaccharide biosynthesis protein
NL113_RS11565	COG2094	Belongs to the DNA glycosylase MPG family
NL113_RS11570	COG3711	transcriptional antiterminator
NL113_RS11570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NL113_RS11575	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NL113_RS11580	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NL113_RS11585	COG1447	Phosphotransferase system cellobiose-specific component IIA
NL113_RS11590	COG1486	melibiose metabolic process
NL113_RS11595	COG2814	Major facilitator Superfamily
NL113_RS11600	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NL113_RS11605	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NL113_RS11610	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NL113_RS11615	COG1696	Membrane protein involved in D-alanine export
NL113_RS11620	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NL113_RS11630	COG2357	RelA SpoT domain protein
NL113_RS11635	COG1335	isochorismatase
NL113_RS11640	COG0477	Major facilitator Superfamily
NL113_RS11665	COG2234	aminopeptidase activity
NL113_RS11670	COG1414	Transcriptional regulator
NL113_RS11675	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NL113_RS11680	COG0800	Aldolase
NL113_RS11685	COG4948	Mandelate Racemase Muconate Lactonizing
NL113_RS11690	COG2271	Major facilitator Superfamily
NL113_RS11695	COG5522	Integral membrane protein (intg_mem_TP0381)
NL113_RS11700	COG2409	Drug exporters of the RND superfamily
NL113_RS11705	COG2197	response regulator
NL113_RS11710	COG4585	Histidine kinase
NL113_RS11725	COG1442	glycosyl transferase family 8
NL113_RS11730	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NL113_RS11735	COG0346	lactoylglutathione lyase activity
NL113_RS11740	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NL113_RS11745	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NL113_RS11750	COG1346	cytolysis
NL113_RS11755	COG1380	Effector of murein hydrolase LrgA
NL113_RS11770	COG0583	DNA-binding transcription factor activity
NL113_RS11775	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NL113_RS11780	COG0352	thiamine-phosphate diphosphorylase activity
NL113_RS11785	COG1940	carbohydrate kinase activity
NL113_RS11790	COG2115	Belongs to the xylose isomerase family
NL113_RS11795	COG1070	Carbohydrate kinase
NL113_RS11800	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NL113_RS11805	COG3162	membrane
NL113_RS11810	COG0655	NAD(P)H dehydrogenase (quinone) activity
NL113_RS11820	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NL113_RS11825	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NL113_RS11830	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NL113_RS11840	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NL113_RS11845	COG0456	acetyltransferase
NL113_RS11855	COG3314	Sporulation integral membrane protein YlbJ
NL113_RS11860	COG0772	Belongs to the SEDS family
NL113_RS11865	COG0772	Belongs to the SEDS family
NL113_RS11870	COG1473	amidohydrolase
NL113_RS11875	COG0778	Nitroreductase
NL113_RS11885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NL113_RS11895	COG1404	Belongs to the peptidase S8 family
NL113_RS11905	COG3711	transcriptional antiterminator
NL113_RS11910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NL113_RS11910	COG1263	PTS System
NL113_RS11915	COG1621	beta-fructofuranosidase activity
NL113_RS11925	COG0351	phosphomethylpyrimidine kinase
NL113_RS11930	COG1216	Glycosyl transferase, family 2
NL113_RS11935	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NL113_RS11945	COG2233	PERMEase
NL113_RS11950	COG2363	Small membrane protein
NL113_RS11965	COG1131	(ABC) transporter
NL113_RS11985	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NL113_RS11995	COG3253	May function as heme-dependent peroxidase
NL113_RS12000	COG0280	phosphate acetyltransferase
NL113_RS12010	COG1414	Transcriptional regulator
NL113_RS12035	COG2814	Major facilitator Superfamily
NL113_RS12060	COG4844	belongs to the
NL113_RS12065	COG1078	dGTPase activity
NL113_RS12070	COG3465	dGTPase activity
NL113_RS12080	COG1942	4-Oxalocrotonate Tautomerase
NL113_RS12085	COG1994	Peptidase M50
NL113_RS12095	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NL113_RS12110	COG1131	(ABC) transporter
NL113_RS12125	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NL113_RS12130	COG0010	Belongs to the arginase family
NL113_RS12135	COG4506	Protein conserved in bacteria
NL113_RS12140	COG0018	arginyl-trna synthetase
NL113_RS12155	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NL113_RS12160	COG0247	lactate metabolic process
NL113_RS12160	COG2181	nitrate reductase activity
NL113_RS12165	COG0183	Belongs to the thiolase family
NL113_RS12170	COG1250	3-hydroxyacyl-CoA dehydrogenase
NL113_RS12175	COG1960	acyl-CoA dehydrogenase activity
NL113_RS12180	COG1960	acyl-CoA dehydrogenase activity
NL113_RS12185	COG3343	RNA polymerase activity
NL113_RS12190	COG0504	CTP synthase activity
NL113_RS12195	COG4821	SIS domain
NL113_RS12200	COG2204	response regulator
NL113_RS12205	COG0191	fructose-bisphosphate aldolase activity
NL113_RS12210	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NL113_RS12215	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NL113_RS12220	COG1494	fructose-1,6-bisphosphatase
NL113_RS12225	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NL113_RS12235	COG1435	thymidine kinase activity
NL113_RS12240	COG0281	malic enzyme
NL113_RS12245	COG0679	Auxin Efflux Carrier
NL113_RS12250	COG0789	Transcriptional regulator
NL113_RS12255	COG0346	lactoylglutathione lyase activity
NL113_RS12260	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NL113_RS12265	COG2890	protein-(glutamine-N5) methyltransferase activity
NL113_RS12270	COG1609	Transcriptional regulator
NL113_RS12275	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NL113_RS12280	COG0561	phosphatase activity
NL113_RS12290	COG0738	Major facilitator superfamily
NL113_RS12300	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
NL113_RS12305	COG0009	L-threonylcarbamoyladenylate synthase
NL113_RS12310	COG1971	Probably functions as a manganese efflux pump
NL113_RS12315	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NL113_RS12320	COG0698	ribose 5-phosphate isomerase
NL113_RS12325	COG4475	Protein of unknown function (DUF436)
NL113_RS12330	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NL113_RS12335	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NL113_RS12345	COG0356	it plays a direct role in the translocation of protons across the membrane
NL113_RS12350	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NL113_RS12355	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NL113_RS12360	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NL113_RS12365	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NL113_RS12370	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NL113_RS12375	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NL113_RS12380	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NL113_RS12385	COG4836	Membrane
NL113_RS12395	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NL113_RS12400	COG2385	sporulation resulting in formation of a cellular spore
NL113_RS12405	COG2304	oxidoreductase activity
NL113_RS12410	COG2304	oxidoreductase activity
NL113_RS12415	COG0243	molybdopterin cofactor binding
NL113_RS12420	COG2223	nitrite transmembrane transporter activity
NL113_RS12425	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NL113_RS12430	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NL113_RS12440	COG1994	Peptidase M50
NL113_RS12450	COG1959	2 iron, 2 sulfur cluster binding
NL113_RS12455	COG2910	NAD(P)H-binding
NL113_RS12465	COG2207	Transcriptional regulator
NL113_RS12465	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NL113_RS12470	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NL113_RS12475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NL113_RS12480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NL113_RS12485	COG2819	hydrolase of the alpha beta superfamily
NL113_RS12490	COG1028	Short-chain dehydrogenase reductase Sdr
NL113_RS12495	COG1169	isochorismate synthase
NL113_RS12500	COG1021	2,3-dihydroxybenzoate-AMP ligase
NL113_RS12505	COG1535	isochorismatase
NL113_RS12505	COG3433	isochorismatase activity
NL113_RS12510	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NL113_RS12515	COG3251	PFAM MbtH domain protein
NL113_RS12520	COG0477	Major facilitator Superfamily
NL113_RS12525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NL113_RS12535	COG1247	-acetyltransferase
NL113_RS12540	COG0739	heme binding
NL113_RS12550	COG0740	serine-type endopeptidase activity
NL113_RS12560	COG0347	Belongs to the P(II) protein family
NL113_RS12565	COG0004	ammonium transporteR
NL113_RS12570	COG1253	flavin adenine dinucleotide binding
NL113_RS12575	COG0598	Magnesium transport protein CorA
NL113_RS12580	COG0517	IMP dehydrogenase activity
NL113_RS12590	COG1309	transcriptional regulator
NL113_RS12595	COG3361	conserved protein (COG2071)
NL113_RS12600	COG3546	catalase activity
NL113_RS12605	COG1227	inorganic diphosphatase activity
NL113_RS12610	COG0671	phosphoesterase, PA-phosphatase related
NL113_RS12615	COG2814	Major facilitator Superfamily
NL113_RS12620	COG1846	Transcriptional regulator
NL113_RS12625	COG1609	Transcriptional regulator
NL113_RS12630	COG1077	Cell shape determining protein MreB Mrl
NL113_RS12635	COG4786	Flagellar basal body rod
NL113_RS12640	COG4786	Flagellar basal body rod
NL113_RS12645	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NL113_RS12650	COG1970	mechanosensitive ion channel activity
NL113_RS12660	COG0629	single-stranded DNA binding
NL113_RS12680	COG3732	PTS system glucitol sorbitol-specific
NL113_RS12690	COG1028	Short-chain dehydrogenase reductase Sdr
NL113_RS12695	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NL113_RS12700	COG1349	DNA-binding transcription factor activity
NL113_RS12705	COG0561	phosphatase activity
NL113_RS12710	COG0804	urea catabolic process
NL113_RS12715	COG0832	Belongs to the urease beta subunit family
NL113_RS12720	COG0831	urea catabolic process
NL113_RS12725	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NL113_RS12730	COG4715	Zinc finger, swim domain protein
NL113_RS12740	COG3944	biosynthesis protein
NL113_RS12745	COG4464	protein tyrosine phosphatase activity
NL113_RS12750	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NL113_RS12755	COG2059	Chromate
NL113_RS12760	COG2059	Chromate
NL113_RS12765	COG1522	sequence-specific DNA binding
NL113_RS12775	COG0583	DNA-binding transcription factor activity
NL113_RS12780	COG0028	Belongs to the TPP enzyme family
NL113_RS12785	COG3527	Alpha-acetolactate decarboxylase
NL113_RS12790	COG2226	methyltransferase
NL113_RS12795	COG0583	DNA-binding transcription factor activity
NL113_RS12800	COG1879	ABC-type sugar transport system periplasmic component
NL113_RS12810	COG1129	ABC transporter
NL113_RS12815	COG1869	D-ribose catabolic process
NL113_RS12820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NL113_RS12825	COG1609	Transcriptional regulator
NL113_RS12830	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NL113_RS12840	COG2843	Capsule synthesis protein
NL113_RS12850	COG0791	NLP P60 protein
NL113_RS12855	COG0561	phosphatase activity
NL113_RS12860	COG1316	TRANSCRIPTIONal
NL113_RS12865	COG2814	Major facilitator Superfamily
NL113_RS12875	COG1063	alcohol dehydrogenase
NL113_RS12880	COG1028	Short-chain dehydrogenase reductase Sdr
NL113_RS12885	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NL113_RS12890	COG1609	Transcriptional regulator
NL113_RS12895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NL113_RS12900	COG0800	Aldolase
NL113_RS12910	COG1328	CTP reductase activity
NL113_RS12920	COG1482	cell wall glycoprotein biosynthetic process
NL113_RS12925	COG4193	domain, Protein
NL113_RS12935	COG0438	transferase activity, transferring glycosyl groups
NL113_RS12940	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NL113_RS12945	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NL113_RS12965	COG4193	domain, Protein
NL113_RS12970	COG1134	teichoic acid transport
NL113_RS12975	COG1682	transport, permease protein
NL113_RS12980	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NL113_RS12990	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NL113_RS12995	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
NL113_RS13000	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NL113_RS13005	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NL113_RS13010	COG1316	TRANSCRIPTIONal
NL113_RS13020	COG2247	cell wall binding repeat
NL113_RS13020	COG2385	sporulation resulting in formation of a cellular spore
NL113_RS13025	COG0860	N-Acetylmuramoyl-L-alanine amidase
NL113_RS13025	COG2247	cell wall binding repeat
NL113_RS13035	COG2244	polysaccharide biosynthetic process
NL113_RS13040	COG0297	glycogen (starch) synthase activity
NL113_RS13040	COG0438	transferase activity, transferring glycosyl groups
NL113_RS13045	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NL113_RS13050	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NL113_RS13055	COG3307	-O-antigen
NL113_RS13060	COG3206	protein involved in exopolysaccharide biosynthesis
NL113_RS13065	COG1215	transferase activity, transferring glycosyl groups
NL113_RS13070	COG0438	transferase activity, transferring glycosyl groups
NL113_RS13075	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NL113_RS13080	COG1316	TRANSCRIPTIONal
NL113_RS13085	COG1739	Uncharacterized protein family UPF0029
NL113_RS13090	COG4585	Histidine kinase
NL113_RS13095	COG2197	response regulator
NL113_RS13100	COG1307	EDD domain protein, DegV family
NL113_RS13105	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NL113_RS13115	COG1040	competence protein
NL113_RS13125	COG2747	anti-sigma28 factor FlgM
NL113_RS13130	COG3418	PFAM FlgN family protein
NL113_RS13135	COG1256	bacterial-type flagellum assembly
NL113_RS13135	COG4786	Flagellar basal body rod
NL113_RS13140	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NL113_RS13150	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NL113_RS13155	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NL113_RS13160	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NL113_RS13165	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NL113_RS13170	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NL113_RS13175	COG1334	flagellar protein FlaG
NL113_RS13180	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NL113_RS13185	COG1516	flagellar protein fliS
NL113_RS13200	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NL113_RS13205	COG0653	protein targeting
NL113_RS13215	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NL113_RS13220	COG2010	Cytochrome c
NL113_RS13225	COG2884	Cell division ATP-binding protein ftsE
NL113_RS13230	COG2177	Part of the ABC transporter FtsEX involved in
NL113_RS13235	COG0791	NLP P60 protein
NL113_RS13235	COG3883	PFAM NLP P60 protein
NL113_RS13240	COG0473	3-isopropylmalate dehydrogenase activity
NL113_RS13245	COG0793	Belongs to the peptidase S41A family
NL113_RS13245	COG3409	Peptidoglycan-binding domain 1 protein
NL113_RS13255	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NL113_RS13265	COG4897	Protein conserved in bacteria
NL113_RS13270	COG0556	nucleotide-excision repair
NL113_RS13275	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NL113_RS13290	COG3595	metallopeptidase activity
NL113_RS13295	COG1983	PspC domain protein
NL113_RS13300	COG1950	PFAM Membrane protein of
NL113_RS13305	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NL113_RS13310	COG2814	Major facilitator Superfamily
NL113_RS13315	COG1846	Transcriptional regulator
NL113_RS13320	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NL113_RS13325	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NL113_RS13330	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NL113_RS13335	COG0546	phosphoglycolate phosphatase activity
NL113_RS13340	COG0110	maltose O-acetyltransferase activity
NL113_RS13345	COG5297	Belongs to the glycosyl hydrolase family 6
NL113_RS13350	COG3858	chitin binding
NL113_RS13355	COG4990	cell redox homeostasis
NL113_RS13360	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NL113_RS13365	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NL113_RS13370	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NL113_RS13375	COG0131	Imidazoleglycerol-phosphate dehydratase
NL113_RS13380	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NL113_RS13385	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NL113_RS13390	COG0107	imidazoleglycerol-phosphate synthase activity
NL113_RS13395	COG0140	phosphoribosyl-ATP diphosphatase activity
NL113_RS13395	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NL113_RS13400	COG0457	Tetratricopeptide repeat
NL113_RS13405	COG0492	ferredoxin-NADP+ reductase activity
NL113_RS13410	COG1051	belongs to the nudix hydrolase family
NL113_RS13415	COG1660	Displays ATPase and GTPase activities
NL113_RS13420	COG0391	Required for morphogenesis under gluconeogenic growth conditions
NL113_RS13425	COG1481	regulation of sporulation
NL113_RS13430	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NL113_RS13435	COG2162	N-hydroxyarylamine O-acetyltransferase activity
NL113_RS13440	COG0745	RESPONSE REGULATOR receiver
NL113_RS13445	COG5002	protein histidine kinase activity
NL113_RS13450	COG1136	(ABC) transporter
NL113_RS13455	COG0577	efflux transmembrane transporter activity
NL113_RS13460	COG0640	Transcriptional regulator
NL113_RS13465	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NL113_RS13470	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NL113_RS13475	COG0288	reversible hydration of carbon dioxide
NL113_RS13480	COG0659	secondary active sulfate transmembrane transporter activity
NL113_RS13485	COG1078	dGTPase activity
NL113_RS13490	COG1694	Mazg nucleotide pyrophosphohydrolase
NL113_RS13495	COG1611	Belongs to the LOG family
NL113_RS13505	COG0740	serine-type endopeptidase activity
NL113_RS13535	COG1621	beta-fructofuranosidase activity
NL113_RS13540	COG1621	beta-fructofuranosidase activity
NL113_RS13545	COG1902	pentaerythritol trinitrate reductase activity
NL113_RS13555	COG2249	NAD(P)H dehydrogenase (quinone) activity
NL113_RS13560	COG1396	sequence-specific DNA binding
NL113_RS13565	COG3944	biosynthesis protein
NL113_RS13570	COG0489	protein tyrosine kinase activity
NL113_RS13575	COG1086	Polysaccharide biosynthesis protein
NL113_RS13580	COG0438	transferase activity, transferring glycosyl groups
NL113_RS13585	COG1215	transferase activity, transferring glycosyl groups
NL113_RS13590	COG0438	transferase activity, transferring glycosyl groups
NL113_RS13600	COG1216	Glycosyl transferase, family 2
NL113_RS13605	COG5039	Polysaccharide pyruvyl transferase
NL113_RS13610	COG1216	Glycosyl transferase, family 2
NL113_RS13615	COG2244	polysaccharide biosynthetic process
NL113_RS13620	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NL113_RS13625	COG0110	maltose O-acetyltransferase activity
NL113_RS13630	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NL113_RS13635	COG5039	Polysaccharide pyruvyl transferase
NL113_RS13645	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
NL113_RS13650	COG1620	l-lactate permease
NL113_RS13655	COG2186	Transcriptional regulator
NL113_RS13660	COG0247	lactate metabolic process
NL113_RS13665	COG1139	Iron-sulfur cluster binding protein
NL113_RS13670	COG1556	Lactate utilization protein
NL113_RS13685	COG4978	Transcriptional regulator
NL113_RS13685	COG0789	Transcriptional regulator
NL113_RS13705	COG1113	amino acid transport
NL113_RS13710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NL113_RS13720	COG2390	Transcriptional regulator
NL113_RS13725	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NL113_RS13730	COG0126	phosphoglycerate kinase activity
NL113_RS13735	COG0149	triose-phosphate isomerase activity
NL113_RS13740	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NL113_RS13745	COG0148	phosphopyruvate hydratase activity
NL113_RS13750	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NL113_RS13755	COG4640	response to antibiotic
NL113_RS13760	COG3064	Membrane
NL113_RS13765	COG2095	MarC family integral membrane protein
NL113_RS13770	COG1510	regulation of RNA biosynthetic process
NL113_RS13775	COG1125	glycine betaine transport
NL113_RS13775	COG0517	IMP dehydrogenase activity
NL113_RS13780	COG1174	glycine betaine transport
NL113_RS13785	COG1732	Glycine betaine
NL113_RS13790	COG1174	glycine betaine transport
NL113_RS13795	COG1396	sequence-specific DNA binding
NL113_RS13800	COG1396	sequence-specific DNA binding
NL113_RS13805	COG1476	TRANSCRIPTIONal
NL113_RS13810	COG2002	toxin-antitoxin pair type II binding
NL113_RS13815	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NL113_RS13820	COG1647	Serine aminopeptidase, S33
NL113_RS13825	COG0557	exoribonuclease II activity
NL113_RS13830	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NL113_RS13855	COG2140	Oxalate decarboxylase
NL113_RS13865	COG1191	sigma factor activity
NL113_RS13875	COG1054	Belongs to the UPF0176 family
NL113_RS13880	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NL113_RS13885	COG0673	inositol 2-dehydrogenase activity
NL113_RS13890	COG1819	glycosyl
NL113_RS13895	COG1846	Transcriptional regulator
NL113_RS13900	COG2814	Major facilitator Superfamily
NL113_RS13905	COG3340	Belongs to the peptidase S51 family
NL113_RS13910	COG2814	Major facilitator Superfamily
NL113_RS13925	COG1070	Carbohydrate kinase
NL113_RS13930	COG1349	DNA-binding transcription factor activity
NL113_RS13935	COG0693	protein deglycase activity
NL113_RS13940	COG1937	Protein conserved in bacteria
NL113_RS13945	COG2608	mercury ion transmembrane transporter activity
NL113_RS13950	COG2217	Heavy metal translocating P-type atpase
NL113_RS13965	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NL113_RS13965	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NL113_RS13965	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NL113_RS13970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NL113_RS13970	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NL113_RS13970	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NL113_RS13975	COG1105	Belongs to the carbohydrate kinase PfkB family
NL113_RS13990	COG0803	Belongs to the bacterial solute-binding protein 9 family
NL113_RS13995	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NL113_RS14000	COG1121	(ABC) transporter
NL113_RS14005	COG1472	Belongs to the glycosyl hydrolase 3 family
NL113_RS14010	COG1501	Belongs to the glycosyl hydrolase 31 family
NL113_RS14015	COG0395	ABC-type sugar transport system, permease component
NL113_RS14020	COG1175	transmembrane transport
NL113_RS14030	COG2217	Heavy metal translocating P-type atpase
NL113_RS14035	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NL113_RS14040	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
NL113_RS14060	COG0456	acetyltransferase
NL113_RS14060	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NL113_RS14065	COG2860	membrane
NL113_RS14070	COG3973	AAA domain
NL113_RS14090	COG1940	carbohydrate kinase activity
NL113_RS14095	COG0656	L-ascorbic acid biosynthetic process
NL113_RS14100	COG2814	Major facilitator Superfamily
NL113_RS14105	COG1368	sulfuric ester hydrolase activity
NL113_RS14110	COG1988	membrane-bound metal-dependent
NL113_RS14120	COG0531	amino acid
NL113_RS14125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NL113_RS14130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NL113_RS14135	COG1120	ATPase activity
NL113_RS14140	COG0745	RESPONSE REGULATOR receiver
NL113_RS14145	COG2205	protein histidine kinase activity
NL113_RS14150	COG1904	glucuronate isomerase
NL113_RS14155	COG2211	Major facilitator Superfamily
NL113_RS14160	COG1609	Transcriptional regulator
NL113_RS14165	COG0246	Mannitol dehydrogenase
NL113_RS14170	COG2721	sulfolactate sulfo-lyase activity
NL113_RS14185	COG2258	MOSC domain
NL113_RS14190	COG1028	Short-chain dehydrogenase reductase Sdr
NL113_RS14200	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NL113_RS14205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NL113_RS14210	COG1120	ATPase activity
NL113_RS14215	COG2096	Adenosyltransferase
NL113_RS14220	COG4677	pectinesterase activity
NL113_RS14225	COG4758	membrane
NL113_RS14230	COG1842	Phage shock protein A
NL113_RS14235	COG3595	metallopeptidase activity
NL113_RS14240	COG4758	membrane
NL113_RS14245	COG4585	Histidine kinase
NL113_RS14250	COG2197	response regulator
NL113_RS14265	COG0814	amino acid
NL113_RS14270	COG0697	spore germination
NL113_RS14280	COG0114	fumarate hydratase activity
NL113_RS14285	COG1309	transcriptional regulator
NL113_RS14295	COG2205	protein histidine kinase activity
NL113_RS14295	COG2770	Histidine kinase
NL113_RS14300	COG0745	RESPONSE REGULATOR receiver
NL113_RS14305	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NL113_RS14310	COG0783	Belongs to the Dps family
NL113_RS14320	COG1686	Belongs to the peptidase S11 family
NL113_RS14335	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NL113_RS14340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NL113_RS14345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NL113_RS14350	COG1120	ATPase activity
NL113_RS14365	COG5577	PFAM Coat F domain
NL113_RS14380	COG1250	3-hydroxyacyl-CoA dehydrogenase
NL113_RS14380	COG1024	Enoyl-CoA hydratase
NL113_RS14385	COG0183	Belongs to the thiolase family
NL113_RS14390	COG1960	acyl-CoA dehydrogenase activity
NL113_RS14395	COG1393	Belongs to the ArsC family
NL113_RS14400	COG0509	glycine decarboxylation via glycine cleavage system
NL113_RS14410	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NL113_RS14415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NL113_RS14425	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NL113_RS14430	COG2011	ABC-type metal ion transport system permease component
NL113_RS14435	COG1464	Belongs to the NlpA lipoprotein family
NL113_RS14440	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NL113_RS14455	COG0396	ATPase activity
NL113_RS14460	COG0719	Fe-S assembly protein
NL113_RS14465	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NL113_RS14470	COG0822	iron-sulfur transferase activity
NL113_RS14475	COG0719	Fe-S assembly protein
NL113_RS14490	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NL113_RS14505	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
NL113_RS14515	COG0482	sulfurtransferase activity
NL113_RS14530	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NL113_RS14535	COG2222	sugar isomerase
NL113_RS14540	COG1653	transport
NL113_RS14545	COG1175	transmembrane transport
NL113_RS14550	COG0395	ABC-type sugar transport system, permease component
NL113_RS14555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NL113_RS14560	COG2188	Transcriptional regulator
NL113_RS14565	COG3842	ATPase activity
NL113_RS14570	COG2356	endonuclease I
NL113_RS14575	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NL113_RS14580	COG1288	antiporter activity
NL113_RS14585	COG2814	Major facilitator Superfamily
NL113_RS14590	COG2508	Transcriptional regulator
NL113_RS14595	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NL113_RS14600	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NL113_RS14615	COG3226	Transcriptional regulator
NL113_RS14625	COG1801	Protein of unknown function DUF72
NL113_RS14630	COG0730	response to heat
NL113_RS14635	COG0737	Belongs to the 5'-nucleotidase family
NL113_RS14640	COG3377	Domain of unknown function (DUF1805)
NL113_RS14650	COG0733	neurotransmitter:sodium symporter activity
NL113_RS14660	COG0739	heme binding
NL113_RS14675	COG4470	Protein conserved in bacteria
NL113_RS14680	COG2445	Protein of unknown function DUF86
NL113_RS14685	COG0647	UMP catabolic process
NL113_RS14690	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NL113_RS14695	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NL113_RS14700	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NL113_RS14705	COG0460	homoserine dehydrogenase
NL113_RS14710	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NL113_RS14715	COG0083	homoserine kinase activity
NL113_RS14720	COG0823	Involved in the tonB-independent uptake of proteins
NL113_RS14720	COG1506	peptidase
NL113_RS14720	COG4946	Tricorn protease homolog
NL113_RS14730	COG4837	Protein of unknown function (DUF1462)
NL113_RS14740	COG3479	Phenolic acid decarboxylase
NL113_RS14745	COG0457	Tetratricopeptide repeat
NL113_RS14760	COG1252	NADH dehydrogenase
NL113_RS14765	COG4844	belongs to the
NL113_RS14770	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NL113_RS14775	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NL113_RS14780	COG0316	Belongs to the HesB IscA family
NL113_RS14795	COG0492	ferredoxin-NADP+ reductase activity
NL113_RS14800	COG1252	NADH dehydrogenase
NL113_RS14815	COG3584	3D domain protein
NL113_RS14820	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
NL113_RS14825	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NL113_RS14830	COG2056	Na+-H+ antiporter family
NL113_RS14835	COG1268	BioY protein
NL113_RS14840	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NL113_RS14845	COG0686	Belongs to the AlaDH PNT family
NL113_RS14850	COG2508	Transcriptional regulator
NL113_RS14850	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NL113_RS14855	COG1115	amino acid carrier protein
NL113_RS14860	COG4842	Belongs to the WXG100 family
NL113_RS14865	COG5417	Belongs to the EsaB family
NL113_RS14870	COG4499	WXG100 protein secretion system (Wss), protein YukC
NL113_RS14875	COG0433	COG0433 Predicted ATPase
NL113_RS14875	COG1674	ftsk spoiiie
NL113_RS14880	COG1511	domain protein
NL113_RS14895	COG1028	Short-chain dehydrogenase reductase Sdr
NL113_RS14905	COG1418	mRNA catabolic process
NL113_RS14915	COG0657	acetylesterase activity
NL113_RS14920	COG1959	2 iron, 2 sulfur cluster binding
NL113_RS14925	COG0628	permease
NL113_RS14940	COG5506	Protein of unknown function (DUF1694)
NL113_RS14945	COG1335	isochorismatase
NL113_RS14950	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NL113_RS14955	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
NL113_RS14970	COG0142	geranyltranstransferase activity
NL113_RS14980	COG4585	Histidine kinase
NL113_RS14985	COG2197	response regulator
NL113_RS14990	COG2050	protein possibly involved in aromatic compounds catabolism
NL113_RS14995	COG1320	monovalent cation:proton antiporter activity
NL113_RS15000	COG2212	antiporter activity
NL113_RS15005	COG1863	multisubunit Na H antiporter MnhE subunit
NL113_RS15010	COG0651	ATP synthesis coupled electron transport
NL113_RS15015	COG1006	Multisubunit Na H antiporter MnhC subunit
NL113_RS15020	COG2111	Na H antiporter
NL113_RS15025	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NL113_RS15025	COG2111	Na H antiporter
NL113_RS15035	COG3493	citrate carrier protein
NL113_RS15040	COG0688	phosphatidylethanolamine metabolic process
NL113_RS15045	COG0586	Pfam SNARE associated Golgi protein
NL113_RS15050	COG1183	phosphatidylcholine synthase activity
NL113_RS15055	COG1079	Belongs to the binding-protein-dependent transport system permease family
NL113_RS15060	COG4603	Belongs to the binding-protein-dependent transport system permease family
NL113_RS15065	COG3845	ABC transporter
NL113_RS15070	COG1744	ABC transporter substrate-binding protein PnrA-like
NL113_RS15075	COG4565	transcriptional regulatory protein
NL113_RS15080	COG3290	protein histidine kinase activity
NL113_RS15090	COG3011	Protein conserved in bacteria
NL113_RS15095	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NL113_RS15100	COG2814	Major facilitator Superfamily
NL113_RS15105	COG5018	Exonuclease
NL113_RS15120	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NL113_RS15135	COG2267	carboxylic ester hydrolase activity
NL113_RS15140	COG1522	sequence-specific DNA binding
NL113_RS15145	COG0436	Aminotransferase
NL113_RS15150	COG1098	S1 RNA binding domain
NL113_RS15155	COG2155	Conserved Protein
NL113_RS15160	COG1979	alcohol dehydrogenase
NL113_RS15165	COG0166	Belongs to the GPI family
NL113_RS15170	COG2323	membrane
NL113_RS15180	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NL113_RS15195	COG2738	Putative neutral zinc metallopeptidase
NL113_RS15200	COG1253	flavin adenine dinucleotide binding
NL113_RS15205	COG5297	Belongs to the glycosyl hydrolase family 6
NL113_RS15215	COG0432	Pfam Uncharacterised protein family UPF0047
NL113_RS15235	COG0840	transmembrane signaling receptor activity
NL113_RS15240	COG0840	transmembrane signaling receptor activity
NL113_RS15245	COG0673	inositol 2-dehydrogenase activity
NL113_RS15250	COG0628	permease
NL113_RS15255	COG1968	undecaprenyl-diphosphatase activity
NL113_RS15260	COG1408	metallophosphoesterase
NL113_RS15265	COG0726	polysaccharide deacetylase
NL113_RS15270	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NL113_RS15345	COG1510	regulation of RNA biosynthetic process
NL113_RS15350	COG1012	belongs to the aldehyde dehydrogenase family
NL113_RS15355	COG1454	alcohol dehydrogenase
NL113_RS15365	COG2318	DinB family
NL113_RS15370	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NL113_RS15375	COG0569	domain protein
NL113_RS15380	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NL113_RS15385	COG0457	Tetratricopeptide repeat
NL113_RS15400	COG3764	Sortase (surface protein transpeptidase)
NL113_RS15405	COG3859	Proton-coupled thiamine transporter YuaJ
NL113_RS15410	COG1609	Transcriptional regulator
NL113_RS15550	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NL113_RS15555	COG1575	Belongs to the MenA family. Type 1 subfamily
NL113_RS15560	COG1169	isochorismate synthase
NL113_RS15565	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NL113_RS15570	COG0596	Alpha beta hydrolase
NL113_RS15575	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NL113_RS15580	COG0318	PFAM AMP-dependent synthetase and ligase
NL113_RS15585	COG4948	Mandelate Racemase Muconate Lactonizing
NL113_RS15590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NL113_RS15595	COG0456	acetyltransferase
NL113_RS15600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NL113_RS15605	COG0765	amino acid transport
NL113_RS15610	COG1126	abc transporter atp-binding protein
NL113_RS15615	COG1473	amidohydrolase
NL113_RS15620	COG2079	MmgE PrpD family protein
NL113_RS15635	COG1294	oxidase, subunit
NL113_RS15640	COG1271	oxidase subunit
NL113_RS15645	COG0254	rRNA binding
NL113_RS15650	COG0803	Belongs to the bacterial solute-binding protein 9 family
NL113_RS15655	COG0288	reversible hydration of carbon dioxide
NL113_RS15660	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NL113_RS15665	COG1854	S-ribosylhomocysteine lyase activity
NL113_RS15680	COG0783	Belongs to the Dps family
NL113_RS15685	COG4824	toxin secretion phage lysis holin
NL113_RS15700	COG0494	nUDIX hydrolase
NL113_RS15705	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NL113_RS15710	COG1116	anion transmembrane transporter activity
NL113_RS15715	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NL113_RS15720	COG1506	peptidase
NL113_RS15735	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NL113_RS15740	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NL113_RS15745	COG0367	asparagine synthase
NL113_RS15750	COG0438	transferase activity, transferring glycosyl groups
NL113_RS15755	COG0671	phosphoesterase, PA-phosphatase related
NL113_RS15760	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NL113_RS15765	COG2267	carboxylic ester hydrolase activity
NL113_RS15775	COG1301	dicarboxylic acid transport
NL113_RS15780	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
NL113_RS15785	COG1242	4 iron, 4 sulfur cluster binding
NL113_RS15800	COG1725	Transcriptional regulator
NL113_RS15805	COG1131	(ABC) transporter
NL113_RS15815	COG1136	(ABC) transporter
NL113_RS15820	COG0577	efflux transmembrane transporter activity
NL113_RS15825	COG0109	protoheme IX farnesyltransferase activity
NL113_RS15840	COG2814	Major facilitator Superfamily
NL113_RS15850	COG0495	leucyl-tRNA aminoacylation
NL113_RS15855	COG0346	lactoylglutathione lyase activity
NL113_RS15860	COG0583	DNA-binding transcription factor activity
NL113_RS15870	COG1073	alpha beta
NL113_RS15875	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NL113_RS15880	COG0395	ABC-type sugar transport system, permease component
NL113_RS15885	COG1653	transport
NL113_RS15890	COG2207	Transcriptional regulator
NL113_RS15895	COG4209	transmembrane transport
NL113_RS15900	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NL113_RS15905	COG1653	transport
NL113_RS15910	COG0673	inositol 2-dehydrogenase activity
NL113_RS15915	COG5578	integral membrane protein
NL113_RS15925	COG0457	Tetratricopeptide repeat
NL113_RS15935	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NL113_RS15940	COG0471	metal ion transport
NL113_RS15945	COG1053	succinate dehydrogenase
NL113_RS15950	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NL113_RS15955	COG2048	Heterodisulfide reductase, subunit B
NL113_RS15975	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NL113_RS15980	COG3395	kinase activity
NL113_RS15985	COG1349	DNA-binding transcription factor activity
NL113_RS15990	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NL113_RS15995	COG2081	HI0933 family
NL113_RS16000	COG2244	polysaccharide biosynthetic process
NL113_RS16005	COG1187	pseudouridine synthase activity
NL113_RS16010	COG1349	DNA-binding transcription factor activity
NL113_RS16015	COG2252	PERMEase
NL113_RS16020	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NL113_RS16025	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NL113_RS16030	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NL113_RS16040	COG1597	lipid kinase activity
NL113_RS16045	COG0510	thiamine kinase activity
NL113_RS16055	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NL113_RS16060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NL113_RS16065	COG0281	malic enzyme
NL113_RS16070	COG5584	Small secreted protein
NL113_RS16075	COG1363	Peptidase, m42
NL113_RS16085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NL113_RS16090	COG4848	Belongs to the UPF0354 family
NL113_RS16095	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NL113_RS16100	COG1674	ftsk spoiiie
NL113_RS16105	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NL113_RS16110	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NL113_RS16115	COG4980	gas vesicle protein
NL113_RS16120	COG3118	belongs to the thioredoxin family
NL113_RS16130	COG1605	Chorismate mutase
NL113_RS16130	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
NL113_RS16135	COG1609	Transcriptional regulator
NL113_RS16140	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NL113_RS16145	COG1360	Flagellar Motor Protein
NL113_RS16150	COG0123	including yeast histone deacetylase and acetoin utilization protein
NL113_RS16155	COG0517	IMP dehydrogenase activity
NL113_RS16160	COG0454	-acetyltransferase
NL113_RS16165	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NL113_RS16170	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NL113_RS16175	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NL113_RS16180	COG2199	diguanylate cyclase activity
NL113_RS16180	COG2203	Gaf domain
NL113_RS16185	COG1956	GAF domain-containing protein
NL113_RS16190	COG1309	transcriptional regulator
NL113_RS16195	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NL113_RS16200	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NL113_RS16210	COG1104	cysteine desulfurase activity
NL113_RS16215	COG0301	tRNA thio-modification
NL113_RS16225	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NL113_RS16235	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NL113_RS16240	COG0616	signal peptide processing
NL113_RS16245	COG1714	RDD family
NL113_RS16255	COG3874	Sporulation protein YtfJ
NL113_RS16260	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NL113_RS16265	COG0827	DNA restriction-modification system
NL113_RS16270	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NL113_RS16275	COG0521	Mo-molybdopterin cofactor biosynthetic process
NL113_RS16280	COG0137	argininosuccinate synthase activity
NL113_RS16285	COG0165	Argininosuccinate lyase
NL113_RS16295	COG1028	Short-chain dehydrogenase reductase Sdr
NL113_RS16300	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NL113_RS16305	COG1695	Transcriptional regulator
NL113_RS16310	COG4109	DRTGG domain
NL113_RS16320	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NL113_RS16340	COG0587	DNA-directed DNA polymerase activity
NL113_RS16345	COG0281	malic enzyme
NL113_RS16350	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NL113_RS16355	COG0825	malonyl-CoA metabolic process
NL113_RS16360	COG0205	6-phosphofructokinase activity
NL113_RS16370	COG3030	protein affecting phage T7 exclusion by the F plasmid
NL113_RS16375	COG0628	permease
NL113_RS16380	COG2707	UPF0756 membrane protein
NL113_RS16385	COG0372	Belongs to the citrate synthase family
NL113_RS16390	COG0538	isocitrate dehydrogenase activity
NL113_RS16395	COG0039	L-malate dehydrogenase activity
NL113_RS16400	COG0745	RESPONSE REGULATOR receiver
NL113_RS16405	COG5002	protein histidine kinase activity
NL113_RS16410	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NL113_RS16410	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NL113_RS16415	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NL113_RS16420	COG1971	Probably functions as a manganese efflux pump
NL113_RS16425	COG0237	dephospho-CoA kinase activity
NL113_RS16430	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NL113_RS16435	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NL113_RS16445	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NL113_RS16450	COG3611	Membrane attachment protein
NL113_RS16455	COG1484	DNA-dependent DNA replication
NL113_RS16460	COG0398	Pfam SNARE associated Golgi protein
NL113_RS16475	COG1011	Hydrolase
NL113_RS16485	COG3275	phosphorelay sensor kinase activity
NL113_RS16490	COG3279	Response regulator of the LytR AlgR family
NL113_RS16495	COG3540	Alkaline phosphatase
NL113_RS16500	COG1380	Effector of murein hydrolase LrgA
NL113_RS16505	COG1346	cytolysis
NL113_RS16510	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NL113_RS16515	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NL113_RS16520	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NL113_RS16525	COG3326	Membrane
NL113_RS16535	COG1363	Peptidase, m42
NL113_RS16540	COG3507	Belongs to the glycosyl hydrolase 43 family
NL113_RS16555	COG0235	Class ii aldolase
NL113_RS16560	COG0371	Dehydrogenase
NL113_RS16565	COG1653	transport
NL113_RS16570	COG1175	transmembrane transport
NL113_RS16575	COG0395	ABC-type sugar transport system, permease component
NL113_RS16595	COG3402	PFAM membrane-flanked domain
NL113_RS16600	COG1309	transcriptional regulator
NL113_RS16605	COG1966	Carbon starvation protein
NL113_RS16615	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NL113_RS16620	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NL113_RS16625	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NL113_RS16625	COG0072	phenylalanine-tRNA ligase activity
NL113_RS16645	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NL113_RS16650	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NL113_RS16655	COG1286	toxin biosynthetic process
NL113_RS16660	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NL113_RS16660	COG1796	DNA polymerase
NL113_RS16665	COG1193	negative regulation of DNA recombination
NL113_RS16670	COG3766	membrane
NL113_RS16675	COG0318	PFAM AMP-dependent synthetase and ligase
NL113_RS16680	COG1309	transcriptional regulator
NL113_RS16685	COG1024	Enoyl-CoA hydratase
NL113_RS16690	COG2086	electron transfer activity
NL113_RS16695	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
NL113_RS16700	COG3118	belongs to the thioredoxin family
NL113_RS16705	COG0322	excinuclease ABC activity
NL113_RS16710	COG0527	aspartate kinase activity
NL113_RS16715	COG1719	4-vinyl reductase, 4VR
NL113_RS16720	COG2009	succinate dehydrogenase
NL113_RS16725	COG1053	succinate dehydrogenase
NL113_RS16730	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NL113_RS16735	COG0824	Thioesterase
NL113_RS16740	COG1028	Short-chain dehydrogenase reductase Sdr
NL113_RS16745	COG2197	response regulator
NL113_RS16750	COG1846	Transcriptional regulator
NL113_RS16755	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NL113_RS16760	COG3420	alginic acid biosynthetic process
NL113_RS16765	COG5401	PFAM Sporulation and spore germination
NL113_RS16770	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NL113_RS16775	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NL113_RS16780	COG0622	Phosphoesterase
NL113_RS16825	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NL113_RS16835	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NL113_RS16840	COG0028	Belongs to the TPP enzyme family
NL113_RS16845	COG0440	acetolactate synthase activity
NL113_RS16850	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NL113_RS16855	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NL113_RS16860	COG0473	3-isopropylmalate dehydrogenase activity
NL113_RS16865	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NL113_RS16870	COG0066	3-isopropylmalate dehydratase activity
NL113_RS16875	COG1477	protein flavinylation
NL113_RS16875	COG0457	Tetratricopeptide repeat
NL113_RS16880	COG0544	peptidyl-prolyl cis-trans isomerase activity
NL113_RS16885	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NL113_RS16890	COG0470	DNA polymerase III
NL113_RS16890	COG1067	ATP-dependent peptidase activity
NL113_RS16895	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NL113_RS16900	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NL113_RS16910	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NL113_RS16915	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NL113_RS16920	COG0181	hydroxymethylbilane synthase activity
NL113_RS16925	COG1587	Uroporphyrinogen-III synthase
NL113_RS16930	COG0113	porphobilinogen synthase activity
NL113_RS16935	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NL113_RS16940	COG1388	LysM domain
NL113_RS16945	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NL113_RS16955	COG0525	valine-tRNA ligase activity
NL113_RS16960	COG0285	dihydrofolate synthase activity
NL113_RS16965	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NL113_RS16975	COG0424	maF-like protein
NL113_RS16980	COG2003	Belongs to the UPF0758 family
NL113_RS16985	COG1077	Cell shape determining protein MreB Mrl
NL113_RS16995	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NL113_RS17000	COG0850	regulation of cytokinetic process
NL113_RS17005	COG2894	cell division
NL113_RS17010	COG0640	Transcriptional regulator
NL113_RS17015	COG3832	glyoxalase III activity
NL113_RS17020	COG0739	heme binding
NL113_RS17025	COG1994	Peptidase M50
NL113_RS17030	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NL113_RS17035	COG2868	ribosomal protein
NL113_RS17040	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NL113_RS17045	COG3290	protein histidine kinase activity
NL113_RS17050	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NL113_RS17055	COG4492	Belongs to the UPF0735 family
NL113_RS17060	COG0077	Prephenate dehydratase
NL113_RS17065	COG1827	regulation of RNA biosynthetic process
NL113_RS17070	COG1104	cysteine desulfurase activity
NL113_RS17075	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NL113_RS17080	COG0157	Belongs to the NadC ModD family
NL113_RS17085	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NL113_RS17090	COG1388	LysM domain
NL113_RS17100	COG0217	transcriptional regulatory protein
NL113_RS17115	COG4195	phage-related replication protein
NL113_RS17120	COG2318	DinB family
NL113_RS17135	COG2112	serine threonine protein kinase
NL113_RS17145	COG0632	four-way junction helicase activity
NL113_RS17150	COG2255	four-way junction helicase activity
NL113_RS17160	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NL113_RS17165	COG0343	queuine tRNA-ribosyltransferase activity
NL113_RS17170	COG1862	Preprotein translocase
NL113_RS17180	COG2323	membrane
NL113_RS17185	COG2244	polysaccharide biosynthetic process
NL113_RS17195	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NL113_RS17195	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NL113_RS17200	COG0490	domain, Protein
NL113_RS17205	COG5416	Lipopolysaccharide assembly protein A domain
NL113_RS17210	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NL113_RS17210	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
NL113_RS17215	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NL113_RS17220	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NL113_RS17225	COG1490	D-aminoacyl-tRNA deacylase activity
NL113_RS17230	COG3103	Sh3 type 3 domain protein
NL113_RS17230	COG4991	sh3 domain protein
NL113_RS17230	COG0860	N-Acetylmuramoyl-L-alanine amidase
NL113_RS17240	COG0124	histidyl-tRNA synthetase
NL113_RS17245	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NL113_RS17255	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NL113_RS17265	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NL113_RS17270	COG1959	2 iron, 2 sulfur cluster binding
NL113_RS17275	COG1104	cysteine desulfurase activity
NL113_RS17280	COG0482	sulfurtransferase activity
NL113_RS17285	COG0457	Tetratricopeptide repeat
NL113_RS17290	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NL113_RS17295	COG3881	PFAM PRC-barrel domain
NL113_RS17310	COG0628	permease
NL113_RS17315	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NL113_RS17320	COG4472	Bacterial protein of unknown function (DUF965)
NL113_RS17325	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NL113_RS17330	COG3906	Belongs to the UPF0473 family
NL113_RS17335	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NL113_RS17340	COG4122	O-methyltransferase activity
NL113_RS17345	COG0826	peptidase U32
NL113_RS17350	COG0826	peptidase U32
NL113_RS17355	COG0572	uridine kinase
NL113_RS17360	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NL113_RS17365	COG0768	penicillin binding
NL113_RS17380	COG2226	methyltransferase
NL113_RS17385	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NL113_RS17390	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NL113_RS17395	COG0626	cystathionine gamma-synthase activity
NL113_RS17420	COG2226	methyltransferase
NL113_RS17425	COG1404	Belongs to the peptidase S8 family
NL113_RS17435	COG1309	transcriptional regulator
NL113_RS17440	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NL113_RS17440	COG2124	cytochrome p450
NL113_RS17450	COG2814	Major facilitator Superfamily
NL113_RS17455	COG0583	DNA-binding transcription factor activity
NL113_RS17465	COG1587	Uroporphyrinogen-III synthase
NL113_RS17470	COG1733	regulation of RNA biosynthetic process
NL113_RS17475	COG2814	Major facilitator Superfamily
NL113_RS17480	COG0656	L-ascorbic acid biosynthetic process
NL113_RS17500	COG2205	protein histidine kinase activity
NL113_RS17505	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NL113_RS17510	COG2169	Transcriptional regulator
NL113_RS17530	COG2350	Protein conserved in bacteria
NL113_RS17550	COG1525	nuclease
NL113_RS17565	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
NL113_RS17565	COG3933	PFAM sigma-54 factor interaction domain-containing protein
NL113_RS17570	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
NL113_RS17575	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NL113_RS17580	COG3715	PTS system
NL113_RS17585	COG3716	PTS system mannose fructose sorbose family IID component
NL113_RS17590	COG1621	beta-fructofuranosidase activity
NL113_RS17595	COG0673	inositol 2-dehydrogenase activity
NL113_RS17600	COG1082	Xylose isomerase domain protein TIM barrel
NL113_RS17605	COG4977	sequence-specific DNA binding
NL113_RS17605	COG1917	Cupin 2, conserved barrel domain protein
NL113_RS17610	COG2211	Major facilitator Superfamily
NL113_RS17615	COG3507	Belongs to the glycosyl hydrolase 43 family
NL113_RS17620	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NL113_RS17625	COG4187	Peptidase family M20/M25/M40
NL113_RS17630	COG0833	amino acid
NL113_RS17645	COG2124	cytochrome p450
NL113_RS17655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NL113_RS17670	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NL113_RS17675	COG1846	Transcriptional regulator
NL113_RS17685	COG0693	protein deglycase activity
NL113_RS17700	COG1263	PTS System
NL113_RS17700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NL113_RS17700	COG2190	(PTS) system
NL113_RS17730	COG1942	4-Oxalocrotonate Tautomerase
NL113_RS17740	COG1028	Short-chain dehydrogenase reductase Sdr
NL113_RS17750	COG1070	Carbohydrate kinase
NL113_RS17755	COG4806	L-rhamnose isomerase
NL113_RS17760	COG0235	Class ii aldolase
NL113_RS17765	COG3254	rhamnose metabolic process
NL113_RS17770	COG2814	Major facilitator Superfamily
NL113_RS17775	COG1454	alcohol dehydrogenase
NL113_RS17780	COG0492	ferredoxin-NADP+ reductase activity
NL113_RS17785	COG1114	Component of the transport system for branched-chain amino acids
NL113_RS17790	COG3409	Peptidoglycan-binding domain 1 protein
NL113_RS17815	COG2197	response regulator
NL113_RS17820	COG4585	Histidine kinase
NL113_RS17825	COG3239	Fatty acid desaturase
NL113_RS17830	COG1733	regulation of RNA biosynthetic process
NL113_RS17835	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
NL113_RS17840	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NL113_RS17865	COG4978	Transcriptional regulator
NL113_RS17865	COG0789	Transcriptional regulator
NL113_RS17885	COG5386	Cell surface protein
NL113_RS17890	COG5386	Cell surface protein
NL113_RS17895	COG5386	Cell surface protein
NL113_RS17915	COG4509	Sortase family
NL113_RS17925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NL113_RS17930	COG1120	ATPase activity
NL113_RS17935	COG2329	Antibiotic biosynthesis monooxygenase
NL113_RS17955	COG2390	Transcriptional regulator
NL113_RS17960	COG0133	tryptophan synthase activity
NL113_RS17995	COG2070	2-Nitropropane dioxygenase
NL113_RS18015	COG2807	transmembrane transport
NL113_RS18035	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NL113_RS18040	COG0583	DNA-binding transcription factor activity
NL113_RS18050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NL113_RS18065	COG2427	Protein of unknown function (DUF1641)
NL113_RS18070	COG3383	formate dehydrogenase (NAD+) activity
NL113_RS18075	COG5609	conserved protein (DUF2294)
NL113_RS18095	COG2755	lipolytic protein G-D-S-L family
NL113_RS18110	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
NL113_RS18115	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NL113_RS18120	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NL113_RS18125	COG1534	Rna-binding protein
NL113_RS18130	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NL113_RS18135	COG1713	HD superfamily hydrolase involved in NAD metabolism
NL113_RS18140	COG0799	negative regulation of ribosome biogenesis
NL113_RS18145	COG2226	methyltransferase
NL113_RS18150	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NL113_RS18155	COG1555	photosystem II stabilization
NL113_RS18155	COG1596	polysaccharide export
NL113_RS18160	COG2131	deaminase
NL113_RS18165	COG0658	competence protein
NL113_RS18165	COG2333	competence protein COMEC
NL113_RS18175	COG1466	dna polymerase III delta subunit
NL113_RS18180	COG0268	Binds directly to 16S ribosomal RNA
NL113_RS18185	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NL113_RS18190	COG0860	N-Acetylmuramoyl-L-alanine amidase
NL113_RS18200	COG0481	GTPase activity
NL113_RS18205	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NL113_RS18210	COG1420	regulation of RNA biosynthetic process
NL113_RS18215	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NL113_RS18220	COG0443	Heat shock 70 kDa protein
NL113_RS18225	COG0484	heat shock protein binding
NL113_RS18230	COG2264	protein methyltransferase activity
NL113_RS18235	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NL113_RS18240	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NL113_RS18245	COG1247	-acetyltransferase
NL113_RS18250	COG1283	sodium-dependent phosphate transmembrane transporter activity
NL113_RS18255	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NL113_RS18260	COG1610	YqeY-like protein
NL113_RS18265	COG1030	water channel activity
NL113_RS18270	COG4864	UPF0365 protein
NL113_RS18285	COG0561	phosphatase activity
NL113_RS18290	COG1702	phosphate starvation-inducible protein PhoH
NL113_RS18295	COG1480	7TM receptor with intracellular HD hydrolase
NL113_RS18300	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NL113_RS18305	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NL113_RS18310	COG0295	cytidine deaminase activity
NL113_RS18315	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NL113_RS18325	COG1381	Involved in DNA repair and RecF pathway recombination
NL113_RS18330	COG0752	glycyl-tRNA synthetase alpha subunit
NL113_RS18335	COG0751	glycine-tRNA ligase activity
NL113_RS18340	COG0517	IMP dehydrogenase activity
NL113_RS18345	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
NL113_RS18350	COG1671	Belongs to the UPF0178 family
NL113_RS18355	COG0358	DNA primase activity
NL113_RS18360	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NL113_RS18365	COG2010	Cytochrome c
NL113_RS18385	COG1515	deoxyribonuclease V activity
NL113_RS18390	COG2384	SAM-dependent methyltransferase
NL113_RS18395	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NL113_RS18400	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NL113_RS18410	COG0513	Belongs to the DEAD box helicase family
NL113_RS18415	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NL113_RS18425	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NL113_RS18430	COG1121	(ABC) transporter
NL113_RS18435	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NL113_RS18440	COG0735	belongs to the Fur family
NL113_RS18445	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
NL113_RS18450	COG4709	membrane
NL113_RS18455	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NL113_RS18460	COG1388	LysM domain
NL113_RS18465	COG5521	maltodextrose utilization protein MalA
NL113_RS18470	COG2839	Protein conserved in bacteria
NL113_RS18475	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NL113_RS18480	COG0477	Major facilitator Superfamily
NL113_RS18485	COG0768	penicillin binding
NL113_RS18490	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NL113_RS18495	COG0573	inorganic phosphate transmembrane transporter activity
NL113_RS18500	COG0581	inorganic phosphate transmembrane transporter activity
NL113_RS18505	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NL113_RS18510	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NL113_RS18515	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NL113_RS18530	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NL113_RS18540	COG0457	Tetratricopeptide repeat
NL113_RS18540	COG0705	Rhomboid family
NL113_RS18545	COG0697	spore germination
NL113_RS18550	COG4483	Protein conserved in bacteria
NL113_RS18555	COG1940	carbohydrate kinase activity
NL113_RS18560	COG1368	sulfuric ester hydrolase activity
NL113_RS18565	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NL113_RS18570	COG2866	Carboxypeptidase
NL113_RS18580	COG0011	TIGRFAM Protein of
NL113_RS18590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NL113_RS18600	COG1393	Belongs to the ArsC family
NL113_RS18610	COG1366	Belongs to the anti-sigma-factor antagonist family
NL113_RS18615	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NL113_RS18620	COG1459	type II secretion system
NL113_RS18625	COG4537	Required for transformation and DNA binding
NL113_RS18630	COG4970	Tfp pilus assembly protein FimT
NL113_RS18640	COG4940	Competence protein ComGF
NL113_RS18665	COG0681	Belongs to the peptidase S26 family
NL113_RS18690	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NL113_RS18695	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NL113_RS18700	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NL113_RS18705	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NL113_RS18710	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NL113_RS18715	COG0095	Lipoate-protein ligase
NL113_RS18720	COG1321	iron dependent repressor
NL113_RS18725	COG1752	Esterase of the alpha-beta hydrolase superfamily
NL113_RS18735	COG3872	metal-dependent enzyme
NL113_RS18745	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NL113_RS18750	COG0006	proline dipeptidase activity
NL113_RS18755	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NL113_RS18765	COG3854	ATPases associated with a variety of cellular activities
NL113_RS18805	COG0511	ligase activity, forming carbon-carbon bonds
NL113_RS18810	COG0439	Biotin carboxylase
NL113_RS18815	COG1302	Protein conserved in bacteria
NL113_RS18820	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NL113_RS18825	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NL113_RS18830	COG1570	exodeoxyribonuclease VII activity
NL113_RS18835	COG1722	exodeoxyribonuclease VII activity
NL113_RS18840	COG0142	geranyltranstransferase activity
NL113_RS18845	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NL113_RS18850	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
NL113_RS18855	COG1438	arginine binding
NL113_RS18860	COG0497	DNA recombination
NL113_RS18865	COG0750	zinc metalloprotease
NL113_RS18870	COG0745	RESPONSE REGULATOR receiver
NL113_RS18890	COG1619	proteins homologs of microcin C7 resistance protein MccF
NL113_RS18905	COG0860	N-Acetylmuramoyl-L-alanine amidase
NL113_RS18910	COG0584	glycerophosphoryl diester phosphodiesterase
NL113_RS18920	COG3290	protein histidine kinase activity
NL113_RS18920	COG3829	transcription factor binding
NL113_RS18925	COG0280	phosphate acetyltransferase
NL113_RS18935	COG3426	butyrate kinase activity
NL113_RS18940	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NL113_RS18945	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NL113_RS18950	COG0022	dehydrogenase e1 component
NL113_RS18955	COG0508	dehydrogenase complex catalyzes the overall conversion of
NL113_RS18960	COG1597	lipid kinase activity
NL113_RS18970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NL113_RS18975	COG0765	amino acid transport
NL113_RS18980	COG1126	abc transporter atp-binding protein
NL113_RS18985	COG4129	membrane
NL113_RS18995	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NL113_RS19000	COG2195	Cleaves the N-terminal amino acid of tripeptides
NL113_RS19010	COG0706	membrane insertase activity
NL113_RS19020	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NL113_RS19025	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NL113_RS19030	COG1028	Short-chain dehydrogenase reductase Sdr
NL113_RS19035	COG1785	Belongs to the alkaline phosphatase family
NL113_RS19040	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NL113_RS19045	COG1447	Phosphotransferase system cellobiose-specific component IIA
NL113_RS19050	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NL113_RS19055	COG2723	6-phospho-beta-galactosidase activity
NL113_RS19060	COG2188	Transcriptional regulator
NL113_RS19065	COG2358	TRAP transporter, solute receptor (TAXI family
NL113_RS19080	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NL113_RS19085	COG1234	tRNA 3'-trailer cleavage
NL113_RS19090	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NL113_RS19095	COG0596	Alpha beta hydrolase
NL113_RS19100	COG1902	pentaerythritol trinitrate reductase activity
NL113_RS19105	COG4187	Peptidase family M20/M25/M40
NL113_RS19110	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NL113_RS19115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NL113_RS19120	COG0300	oxidoreductase activity
NL113_RS19125	COG4195	phage-related replication protein
NL113_RS19135	COG2814	Major facilitator Superfamily
NL113_RS19140	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
NL113_RS19160	COG0745	RESPONSE REGULATOR receiver
NL113_RS19165	COG2205	protein histidine kinase activity
NL113_RS19195	COG1131	(ABC) transporter
NL113_RS19205	COG1072	(Pantothenic acid kinase))
NL113_RS19210	COG0346	lactoylglutathione lyase activity
NL113_RS19215	COG2211	Major facilitator Superfamily
NL113_RS19230	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NL113_RS19245	COG0534	Mate efflux family protein
NL113_RS19255	COG0444	Belongs to the ABC transporter superfamily
NL113_RS19260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NL113_RS19265	COG0601	transmembrane transport
NL113_RS19270	COG0747	negative chemotaxis
NL113_RS19280	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NL113_RS19290	COG0456	acetyltransferase
NL113_RS19295	COG2329	Antibiotic biosynthesis monooxygenase
NL113_RS19300	COG0456	acetyltransferase
NL113_RS19300	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NL113_RS19310	COG4918	Iron-sulphur cluster biosynthesis
NL113_RS19320	COG1073	alpha beta
NL113_RS19330	COG0667	Aldo Keto reductase
NL113_RS19340	COG1309	transcriptional regulator
NL113_RS19350	COG0494	nUDIX hydrolase
NL113_RS19355	COG1379	DNA repair
NL113_RS19360	COG2153	protein acetylation
NL113_RS19375	COG1953	Uracil, thiamine, allantoin
NL113_RS19385	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NL113_RS19390	COG1300	Membrane
NL113_RS19395	COG0735	belongs to the Fur family
NL113_RS19405	COG4974	Belongs to the 'phage' integrase family
NL113_RS19410	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NL113_RS19415	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NL113_RS19420	COG1686	Belongs to the peptidase S11 family
NL113_RS19455	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NL113_RS19470	COG0697	spore germination
NL113_RS19480	COG0019	diaminopimelate decarboxylase activity
NL113_RS19485	COG4195	phage-related replication protein
NL113_RS19490	COG4086	secreted protein
NL113_RS19495	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NL113_RS19500	COG0457	Tetratricopeptide repeat
NL113_RS19520	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NL113_RS19520	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NL113_RS19525	COG0307	riboflavin synthase, alpha
NL113_RS19530	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NL113_RS19530	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NL113_RS19535	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NL113_RS19540	COG0456	acetyltransferase
NL113_RS19545	COG1547	Domain of unknown function (DUF309)
NL113_RS19555	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NL113_RS19560	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NL113_RS19570	COG1686	Belongs to the peptidase S11 family
NL113_RS19575	COG2715	membrane protein required for spore maturation
NL113_RS19580	COG0700	Nucleoside recognition
NL113_RS19585	COG1187	pseudouridine synthase activity
NL113_RS19590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NL113_RS19595	COG1333	cytochrome c biogenesis protein
NL113_RS19600	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NL113_RS19605	COG0745	RESPONSE REGULATOR receiver
NL113_RS19610	COG5002	protein histidine kinase activity
NL113_RS19615	COG0745	RESPONSE REGULATOR receiver
NL113_RS19620	COG5002	protein histidine kinase activity
NL113_RS19635	COG1316	TRANSCRIPTIONal
NL113_RS19640	COG1595	DNA-templated transcription, initiation
NL113_RS19650	COG0739	heme binding
NL113_RS19655	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NL113_RS19660	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NL113_RS19665	COG1141	Ferredoxin
NL113_RS19670	COG4955	Helix-turn-helix domain
NL113_RS19675	COG0514	ATP-dependent DNA helicase (RecQ)
NL113_RS19680	COG1266	CAAX protease self-immunity
NL113_RS19685	COG1388	LysM domain
NL113_RS19695	COG1408	metallophosphoesterase
NL113_RS19700	COG4862	establishment of competence for transformation
NL113_RS19705	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NL113_RS19710	COG0492	ferredoxin-NADP+ reductase activity
NL113_RS19720	COG2339	peptidase activity
NL113_RS19725	COG3773	Cell wall hydrolase
NL113_RS19725	COG3409	Peptidoglycan-binding domain 1 protein
NL113_RS19730	COG2959	enzyme of heme biosynthesis
NL113_RS19740	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NL113_RS19745	COG0539	negative regulation of cytoplasmic translation
NL113_RS19750	COG1304	FMN binding
NL113_RS19775	COG1160	GTP binding
NL113_RS19780	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NL113_RS19795	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NL113_RS19800	COG0776	regulation of translation
NL113_RS19805	COG0302	gtp cyclohydrolase
NL113_RS19815	COG0142	geranyltranstransferase activity
NL113_RS19820	COG2226	methyltransferase
NL113_RS19825	COG0142	geranyltranstransferase activity
NL113_RS19830	COG0105	UTP biosynthetic process
NL113_RS19835	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NL113_RS19840	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NL113_RS19845	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NL113_RS19850	COG4401	Chorismate mutase type I
NL113_RS19855	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NL113_RS19860	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NL113_RS19865	COG0134	indole-3-glycerol-phosphate synthase activity
NL113_RS19870	COG0135	phosphoribosylanthranilate isomerase activity
NL113_RS19875	COG0133	tryptophan synthase activity
NL113_RS19880	COG0159	tryptophan synthase activity
NL113_RS19885	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NL113_RS19890	COG0287	Prephenate dehydrogenase
NL113_RS19895	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NL113_RS19900	COG0457	Tetratricopeptide repeat
NL113_RS19905	COG5582	Belongs to the UPF0302 family
NL113_RS19915	COG0723	plastoquinol--plastocyanin reductase activity
NL113_RS19920	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NL113_RS19925	COG2010	Cytochrome c
NL113_RS19925	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NL113_RS19930	COG4347	Protein of unknown function (DUF1405)
NL113_RS19940	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NL113_RS19945	COG1694	Mazg nucleotide pyrophosphohydrolase
NL113_RS19950	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NL113_RS19955	COG1803	Methylglyoxal synthase
NL113_RS19960	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NL113_RS19965	COG0438	transferase activity, transferring glycosyl groups
NL113_RS19970	COG0617	tRNA 3'-terminal CCA addition
NL113_RS19980	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NL113_RS19985	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NL113_RS19990	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NL113_RS19995	COG1199	ATP-dependent helicase activity
NL113_RS19995	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NL113_RS20005	COG5353	protein conserved in bacteria
NL113_RS20010	COG0436	Aminotransferase
NL113_RS20015	COG0017	Asparaginyl-tRNA synthetase
NL113_RS20020	COG3935	DnaD domain protein
NL113_RS20025	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NL113_RS20035	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NL113_RS20035	COG4499	WXG100 protein secretion system (Wss), protein YukC
NL113_RS20040	COG3331	DNA recombination
NL113_RS20075	COG0071	Belongs to the small heat shock protein (HSP20) family
NL113_RS20080	COG2190	(PTS) system
NL113_RS20085	COG1111	helicase
NL113_RS20085	COG1205	dead DEAH box helicase
NL113_RS20090	COG3359	exonuclease
NL113_RS20100	COG4474	Belongs to the UPF0398 family
NL113_RS20105	COG3599	regulation of cell shape
NL113_RS20115	COG0116	Belongs to the methyltransferase superfamily
NL113_RS20130	COG1199	ATP-dependent helicase activity
NL113_RS20135	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NL113_RS20140	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NL113_RS20145	COG2233	PERMEase
NL113_RS20150	COG1247	-acetyltransferase
NL113_RS20155	COG3424	synthase
NL113_RS20160	COG1755	Isoprenylcysteine carboxyl methyltransferase
NL113_RS20170	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NL113_RS20185	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NL113_RS20195	COG0328	RNA-DNA hybrid ribonuclease activity
NL113_RS20200	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NL113_RS20225	COG1278	Cold shock
NL113_RS20235	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NL113_RS20240	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
NL113_RS20245	COG2759	Belongs to the formate--tetrahydrofolate ligase family
NL113_RS20250	COG0386	Belongs to the glutathione peroxidase family
NL113_RS20255	COG1418	mRNA catabolic process
NL113_RS20260	COG1413	lyase activity
NL113_RS20265	COG0129	dihydroxy-acid dehydratase activity
NL113_RS20275	COG2521	methyltransferase
NL113_RS20275	COG2136	Putative SAM-dependent methyltransferase
NL113_RS20285	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NL113_RS20290	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NL113_RS20295	COG0204	Acyl-transferase
NL113_RS20300	COG1272	protein, Hemolysin III
NL113_RS20305	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
NL113_RS20310	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NL113_RS20320	COG1307	EDD domain protein, DegV family
NL113_RS20325	COG1999	signal sequence binding
NL113_RS20330	COG2755	lipolytic protein G-D-S-L family
NL113_RS20335	COG4698	Protein conserved in bacteria
NL113_RS20350	COG0534	Mate efflux family protein
NL113_RS20360	COG1846	Transcriptional regulator
NL113_RS20370	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NL113_RS20375	COG0456	acetyltransferase
NL113_RS20390	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NL113_RS20395	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NL113_RS20400	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NL113_RS20405	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NL113_RS20410	COG0456	acetyltransferase
NL113_RS20415	COG1509	lysine 2,3-aminomutase activity
NL113_RS20425	COG4479	Belongs to the UPF0346 family
NL113_RS20445	COG0671	phosphoesterase, PA-phosphatase related
NL113_RS20465	COG0701	Predicted permease
NL113_RS20470	COG0813	purine-nucleoside phosphorylase activity
NL113_RS20475	COG1876	peptidase activity
NL113_RS20485	COG2226	methyltransferase
NL113_RS20490	COG0793	Belongs to the peptidase S41A family
NL113_RS20490	COG3409	Peptidoglycan-binding domain 1 protein
NL113_RS20495	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NL113_RS20505	COG0346	lactoylglutathione lyase activity
NL113_RS20510	COG0400	carboxylic ester hydrolase activity
NL113_RS20515	COG0778	Nitroreductase
NL113_RS20520	COG1733	regulation of RNA biosynthetic process
NL113_RS20525	COG1028	Short-chain dehydrogenase reductase Sdr
NL113_RS20535	COG4305	rare lipoprotein A
NL113_RS20545	COG2962	Rard protein
NL113_RS20555	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NL113_RS20560	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NL113_RS20565	COG0534	Mate efflux family protein
NL113_RS20570	COG0791	NLP P60 protein
NL113_RS20570	COG1388	LysM domain
NL113_RS20575	COG2032	superoxide dismutase activity
NL113_RS20580	COG0714	Associated with various cellular activities
NL113_RS20585	COG4548	von Willebrand factor, type A
NL113_RS20590	COG0567	Dehydrogenase, E1 component
NL113_RS20595	COG0508	dehydrogenase complex catalyzes the overall conversion of
NL113_RS20600	COG0385	Bile acid
NL113_RS20605	COG0733	neurotransmitter:sodium symporter activity
NL113_RS20610	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NL113_RS20615	COG1657	PFAM Prenyltransferase squalene oxidase
NL113_RS20625	COG0667	Aldo Keto reductase
NL113_RS20645	COG1012	belongs to the aldehyde dehydrogenase family
NL113_RS20660	COG2140	Oxalate decarboxylase
NL113_RS20665	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NL113_RS20670	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NL113_RS20710	COG4555	ABC transporter
NL113_RS20725	COG0602	queuosine metabolic process
NL113_RS20730	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NL113_RS20735	COG2318	DinB family
NL113_RS20755	COG1309	transcriptional regulator
NL113_RS20765	COG3848	Pyruvate phosphate dikinase
NL113_RS20765	COG0574	Belongs to the PEP-utilizing enzyme family
NL113_RS20770	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NL113_RS20780	COG1280	lysine exporter protein (LysE YggA)
NL113_RS20795	COG1357	PFAM Pentapeptide repeats (8 copies)
NL113_RS20800	COG1028	Short-chain dehydrogenase reductase Sdr
NL113_RS20835	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NL113_RS20850	COG2323	membrane
NL113_RS20880	COG1660	Displays ATPase and GTPase activities
NL113_RS20885	COG0789	Transcriptional regulator
NL113_RS20890	COG4221	oxidoreductase activity
NL113_RS20920	COG5646	InterPro IPR014922
NL113_RS20955	COG0514	ATP-dependent DNA helicase (RecQ)
NL113_RS20960	COG3584	3D domain protein
NL113_RS20960	COG1388	LysM domain
NL113_RS20965	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NL113_RS20975	COG2322	membrane
NL113_RS21000	COG0741	lytic transglycosylase activity
NL113_RS21005	COG0531	amino acid
NL113_RS21015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NL113_RS21020	COG0640	Transcriptional regulator
NL113_RS21030	COG2378	regulation of single-species biofilm formation
NL113_RS21040	COG3708	Transcriptional regulator
NL113_RS21045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NL113_RS21050	COG1309	transcriptional regulator
NL113_RS21060	COG1309	transcriptional regulator
NL113_RS21070	COG1404	Belongs to the peptidase S8 family
NL113_RS21080	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NL113_RS21085	COG0840	transmembrane signaling receptor activity
NL113_RS21090	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
NL113_RS21095	COG0697	spore germination
NL113_RS21105	COG0488	(ABC) transporter
NL113_RS21115	COG0697	spore germination
NL113_RS21120	COG0531	amino acid
NL113_RS21125	COG0531	amino acid
NL113_RS21135	COG0531	amino acid
NL113_RS21140	COG2814	Major facilitator Superfamily
NL113_RS21145	COG1846	Transcriptional regulator
NL113_RS21150	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NL113_RS21155	COG0243	molybdopterin cofactor binding
NL113_RS21160	COG0477	Major facilitator Superfamily
NL113_RS21165	COG0300	oxidoreductase activity
NL113_RS21175	COG3540	Alkaline phosphatase
NL113_RS21180	COG1132	(ABC) transporter
NL113_RS21210	COG0583	DNA-binding transcription factor activity
NL113_RS21215	COG0069	glutamate synthase activity
NL113_RS21215	COG0070	glutamate synthase
NL113_RS21215	COG0067	glutamate synthase
NL113_RS21220	COG0493	'glutamate synthase
NL113_RS21235	COG0463	Glycosyl transferase, family 2
NL113_RS21240	COG2814	Major facilitator Superfamily
NL113_RS21245	COG4948	Mandelate Racemase Muconate Lactonizing
NL113_RS21250	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NL113_RS21255	COG1809	phosphosulfolactate synthase activity
NL113_RS21260	COG0175	sulfate reduction
NL113_RS21270	COG2046	Belongs to the sulfate adenylyltransferase family
NL113_RS21275	COG0529	Catalyzes the synthesis of activated sulfate
NL113_RS21280	COG2323	membrane
NL113_RS21285	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NL113_RS21290	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NL113_RS21295	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NL113_RS21300	COG1960	acyl-CoA dehydrogenase activity
NL113_RS21305	COG0318	PFAM AMP-dependent synthetase and ligase
NL113_RS21310	COG0439	Biotin carboxylase
NL113_RS21315	COG0511	ligase activity, forming carbon-carbon bonds
NL113_RS21320	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NL113_RS21325	COG1024	Enoyl-CoA hydratase
NL113_RS21330	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NL113_RS21335	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NL113_RS21345	COG0166	Belongs to the GPI family
NL113_RS21355	COG1252	NADH dehydrogenase
NL113_RS21360	COG2027	D-alanyl-D-alanine carboxypeptidase
NL113_RS21365	COG1882	Formate acetyltransferase
NL113_RS21370	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NL113_RS21375	COG2404	hydrolase activity, acting on ester bonds
NL113_RS21395	COG0640	Transcriptional regulator
NL113_RS21400	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NL113_RS21405	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NL113_RS21410	COG1725	Transcriptional regulator
NL113_RS21440	COG2814	Major facilitator Superfamily
NL113_RS21445	COG0785	Cytochrome C biogenesis protein
NL113_RS21450	COG1309	transcriptional regulator
NL113_RS21460	COG2076	Multidrug Resistance protein
NL113_RS21465	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NL113_RS21465	COG3711	transcriptional antiterminator
NL113_RS21470	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NL113_RS21470	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NL113_RS21470	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NL113_RS21475	COG1482	cell wall glycoprotein biosynthetic process
NL113_RS21480	COG1595	DNA-templated transcription, initiation
NL113_RS21485	COG0667	Aldo Keto reductase
NL113_RS21495	COG1960	acyl-CoA dehydrogenase activity
NL113_RS21500	COG2084	Dehydrogenase
NL113_RS21505	COG1012	belongs to the aldehyde dehydrogenase family
NL113_RS21510	COG1024	Enoyl-CoA hydratase
NL113_RS21530	COG2223	nitrite transmembrane transporter activity
NL113_RS21535	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NL113_RS21540	COG1140	nitrate reductase beta subunit
NL113_RS21545	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
NL113_RS21550	COG2181	nitrate reductase activity
NL113_RS21560	COG0517	IMP dehydrogenase activity
NL113_RS21560	COG1125	glycine betaine transport
NL113_RS21565	COG1174	glycine betaine transport
NL113_RS21575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NL113_RS21580	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
NL113_RS21585	COG1687	branched-chain amino acid
NL113_RS21595	COG0457	Tetratricopeptide repeat
NL113_RS21610	COG5609	conserved protein (DUF2294)
NL113_RS21615	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NL113_RS21620	COG3002	Belongs to the UPF0753 family
NL113_RS21645	COG1473	amidohydrolase
NL113_RS21670	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NL113_RS21675	COG1116	anion transmembrane transporter activity
NL113_RS21685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NL113_RS21695	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NL113_RS21705	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
NL113_RS21725	COG2223	nitrite transmembrane transporter activity
NL113_RS21730	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NL113_RS21740	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NL113_RS21745	COG0535	radical SAM domain protein
NL113_RS21760	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NL113_RS21765	COG1140	nitrate reductase beta subunit
NL113_RS21770	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
NL113_RS21775	COG2181	nitrate reductase activity
NL113_RS21785	COG1115	amino acid carrier protein
NL113_RS21810	COG2160	L-arabinose isomerase activity
NL113_RS21825	COG1609	Transcriptional regulator
NL113_RS21830	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NL113_RS21835	COG0187	DNA topoisomerase II activity
NL113_RS21840	COG1832	CoA-binding protein
NL113_RS21845	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
NL113_RS21850	COG4841	protein insertion into membrane
NL113_RS21860	COG0824	Thioesterase
NL113_RS21880	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NL113_RS21885	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NL113_RS21900	COG0071	Belongs to the small heat shock protein (HSP20) family
NL113_RS21910	COG4846	Membrane protein involved in cytochrome C biogenesis
NL113_RS21915	COG2201	protein-glutamate methylesterase activity
NL113_RS21920	COG0785	Cytochrome C biogenesis protein
NL113_RS21930	COG3763	UPF0154 protein
NL113_RS21940	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NL113_RS21945	COG4224	UPF0291 protein
NL113_RS21950	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NL113_RS21955	COG1388	LysM domain
NL113_RS21960	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NL113_RS21965	COG5434	Belongs to the glycosyl hydrolase 28 family
NL113_RS22025	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NL113_RS22030	COG2076	Multidrug Resistance protein
NL113_RS22035	COG2076	Multidrug Resistance protein
NL113_RS22040	COG1309	transcriptional regulator
NL113_RS22045	COG0457	Tetratricopeptide repeat
NL113_RS22050	COG2814	Major facilitator Superfamily
NL113_RS22065	COG4989	oxidoreductase activity
NL113_RS22080	COG1028	Short-chain dehydrogenase reductase Sdr
NL113_RS22105	COG0457	Tetratricopeptide repeat
NL113_RS22110	COG2814	Major facilitator Superfamily
NL113_RS22120	COG1064	alcohol dehydrogenase
NL113_RS22130	COG0756	dUTP diphosphatase activity
NL113_RS22145	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NL113_RS22160	COG0475	glutathione-regulated potassium exporter activity
NL113_RS22165	COG0490	domain, Protein
NL113_RS22180	COG0457	Tetratricopeptide repeat
NL113_RS22205	COG0457	Tetratricopeptide repeat
NL113_RS22210	COG2814	Major facilitator Superfamily
NL113_RS22215	COG3848	Pyruvate phosphate dikinase
NL113_RS22215	COG0574	Belongs to the PEP-utilizing enzyme family
NL113_RS22225	COG0457	Tetratricopeptide repeat
NL113_RS22230	COG2814	Major facilitator Superfamily
NL113_RS22240	COG3716	PTS system mannose fructose sorbose family IID component
NL113_RS22245	COG3715	PTS system
NL113_RS22295	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NL113_RS22355	COG4373	Mu-like prophage FluMu protein gp28
NL113_RS22450	COG0582	viral genome integration into host DNA
NL113_RS22525	COG1196	nuclear chromosome segregation
NL113_RS22525	COG0739	heme binding
NL113_RS22525	COG0741	lytic transglycosylase activity
NL113_RS22530	COG1196	nuclear chromosome segregation
NL113_RS22530	COG0741	lytic transglycosylase activity
NL113_RS22530	COG0739	heme binding
NL113_RS22540	COG1196	nuclear chromosome segregation
NL113_RS22540	COG0741	lytic transglycosylase activity
NL113_RS22540	COG0739	heme binding
NL113_RS22550	COG2433	Pfam Transposase IS66
NL113_RS22560	COG5434	Belongs to the glycosyl hydrolase 28 family
NL113_RS22570	COG5632	N-Acetylmuramoyl-L-alanine amidase
NL113_RS22600	COG0457	Tetratricopeptide repeat
NL113_RS22630	COG5444	nuclease activity
NL113_RS22635	COG4282	regulation of fungal-type cell wall biogenesis
NL113_RS22670	COG2003	Belongs to the UPF0758 family
NL113_RS22685	COG3209	COG3209 Rhs family protein
NL113_RS22695	COG0457	Tetratricopeptide repeat
NL113_RS22750	COG3591	Belongs to the peptidase S1B family
NL113_RS22770	COG0653	protein targeting
NL113_RS22780	COG1136	(ABC) transporter
NL113_RS22850	COG2805	Type II/IV secretion system protein
NL113_RS22925	COG4086	secreted protein
NL113_RS22975	COG3764	Sortase (surface protein transpeptidase)
NL113_RS23025	COG0653	protein targeting
NL113_RS23130	COG1674	ftsk spoiiie
NL113_RS23130	COG1196	nuclear chromosome segregation
NL113_RS23160	COG2002	toxin-antitoxin pair type II binding
NL113_RS23275	COG2814	Major facilitator Superfamily