locus-tag	class	description
G4O42_RS00010	COG0592	DNA-directed DNA polymerase activity
G4O42_RS00015	COG2501	S4 domain
G4O42_RS00030	COG0187	DNA topoisomerase II activity
G4O42_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
G4O42_RS00070	COG0517	IMP dehydrogenase activity
G4O42_RS00070	COG0516	GMP reductase activity
G4O42_RS00075	COG1686	Belongs to the peptidase S11 family
G4O42_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
G4O42_RS00105	COG1428	Deoxynucleoside kinase
G4O42_RS00110	COG1428	Deoxynucleoside kinase
G4O42_RS00115	COG3858	chitin binding
G4O42_RS00115	COG1388	LysM domain
G4O42_RS00120	COG1335	isochorismatase
G4O42_RS00125	COG0590	tRNA wobble adenosine to inosine editing
G4O42_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
G4O42_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
G4O42_RS00145	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
G4O42_RS00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
G4O42_RS00195	COG3853	Toxic anion resistance protein (TelA)
G4O42_RS00200	COG1982	Orn Lys Arg decarboxylase major
G4O42_RS00210	COG3870	Protein conserved in bacteria
G4O42_RS00215	COG1728	Protein conserved in bacteria
G4O42_RS00220	COG0470	DNA polymerase III
G4O42_RS00225	COG1774	PSP1 C-terminal conserved region
G4O42_RS00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
G4O42_RS00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
G4O42_RS00250	COG2002	toxin-antitoxin pair type II binding
G4O42_RS00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G4O42_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G4O42_RS00260	COG0084	hydrolase, TatD family'
G4O42_RS00265	COG3583	domain protein
G4O42_RS00265	COG3584	3D domain protein
G4O42_RS00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
G4O42_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G4O42_RS00285	COG4466	Protein conserved in bacteria
G4O42_RS00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G4O42_RS00305	COG0251	oxidation-reduction process
G4O42_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G4O42_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
G4O42_RS00345	COG2002	toxin-antitoxin pair type II binding
G4O42_RS00350	COG2244	polysaccharide biosynthetic process
G4O42_RS00355	COG3956	TIGRFAM MazG family protein
G4O42_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
G4O42_RS00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
G4O42_RS00380	COG1098	S1 RNA binding domain
G4O42_RS00395	COG2208	phosphoserine phosphatase activity
G4O42_RS00400	COG2304	oxidoreductase activity
G4O42_RS00405	COG0515	serine threonine protein kinase
G4O42_RS00410	COG0037	tRNA processing
G4O42_RS00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G4O42_RS00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G4O42_RS00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G4O42_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G4O42_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
G4O42_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G4O42_RS00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
G4O42_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
G4O42_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G4O42_RS00475	COG1396	sequence-specific DNA binding
G4O42_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G4O42_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
G4O42_RS00565	COG4463	regulation of RNA biosynthetic process
G4O42_RS00570	COG3880	PFAM UvrB UvrC protein
G4O42_RS00580	COG0542	response to heat
G4O42_RS00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
G4O42_RS00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
G4O42_RS00595	COG4956	integral membrane protein (PIN domain superfamily)
G4O42_RS00615	COG1045	serine acetyltransferase
G4O42_RS00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
G4O42_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G4O42_RS00635	COG3688	RNA-binding protein containing a PIN domain
G4O42_RS00640	COG1595	DNA-templated transcription, initiation
G4O42_RS00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G4O42_RS00655	COG0250	Participates in transcription elongation, termination and antitermination
G4O42_RS00680	COG2813	Specifically methylates the guanine in position
G4O42_RS00695	COG1358	cellular component organization or biogenesis
G4O42_RS00720	COG0596	Alpha beta hydrolase
G4O42_RS00815	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
G4O42_RS00830	COG0201	protein transport
G4O42_RS00840	COG0024	Methionine aminopeptidase
G4O42_RS00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G4O42_RS00880	COG1122	ATPase activity
G4O42_RS00885	COG1122	ATPase activity
G4O42_RS00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
G4O42_RS00910	COG2226	methyltransferase
G4O42_RS00915	COG2318	DinB family
G4O42_RS00925	COG0860	N-Acetylmuramoyl-L-alanine amidase
G4O42_RS00930	COG0489	protein tyrosine kinase activity
G4O42_RS00940	COG2194	sulfuric ester hydrolase activity
G4O42_RS00945	COG0726	polysaccharide deacetylase
G4O42_RS01005	COG0738	Major facilitator superfamily
G4O42_RS01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G4O42_RS01020	COG1063	alcohol dehydrogenase
G4O42_RS01025	COG0659	secondary active sulfate transmembrane transporter activity
G4O42_RS01030	COG0385	Bile acid
G4O42_RS01035	COG2819	hydrolase of the alpha beta superfamily
G4O42_RS01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G4O42_RS01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G4O42_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G4O42_RS01055	COG2207	Transcriptional regulator
G4O42_RS01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G4O42_RS01060	COG3876	Protein conserved in bacteria
G4O42_RS01065	COG1472	Belongs to the glycosyl hydrolase 3 family
G4O42_RS01070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G4O42_RS01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G4O42_RS01075	COG1263	PTS System
G4O42_RS01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G4O42_RS01090	COG1683	Conserved Protein
G4O42_RS01120	COG1595	DNA-templated transcription, initiation
G4O42_RS01125	COG5662	AntiSigma factor
G4O42_RS01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
G4O42_RS01135	COG4856	YbbR-like protein
G4O42_RS01170	COG5002	protein histidine kinase activity
G4O42_RS01175	COG1136	(ABC) transporter
G4O42_RS01180	COG0577	efflux transmembrane transporter activity
G4O42_RS01200	COG1346	cytolysis
G4O42_RS01205	COG1380	Effector of murein hydrolase LrgA
G4O42_RS01210	COG1846	Transcriptional regulator
G4O42_RS01215	COG1113	amino acid transport
G4O42_RS01220	COG1011	Hydrolase
G4O42_RS01225	COG4585	Histidine kinase
G4O42_RS01230	COG2197	response regulator
G4O42_RS01235	COG1131	(ABC) transporter
G4O42_RS01275	COG0531	amino acid
G4O42_RS01280	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
G4O42_RS01295	COG0584	glycerophosphoryl diester phosphodiesterase
G4O42_RS01300	COG2271	Major facilitator Superfamily
G4O42_RS01310	COG2368	4-hydroxyphenylacetate
G4O42_RS01320	COG3409	Peptidoglycan-binding domain 1 protein
G4O42_RS01335	COG1397	ADP-ribosylglycohydrolase
G4O42_RS01340	COG5444	nuclease activity
G4O42_RS01350	COG0371	Dehydrogenase
G4O42_RS01360	COG1183	phosphatidylcholine synthase activity
G4O42_RS01365	COG0586	Pfam SNARE associated Golgi protein
G4O42_RS01370	COG0688	phosphatidylethanolamine metabolic process
G4O42_RS01385	COG1301	dicarboxylic acid transport
G4O42_RS01390	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G4O42_RS01395	COG0833	amino acid
G4O42_RS01400	COG2040	homocysteine
G4O42_RS01405	COG1115	amino acid carrier protein
G4O42_RS01410	COG2066	Belongs to the glutaminase family
G4O42_RS01415	COG4191	Histidine kinase
G4O42_RS01420	COG0784	Response regulator, receiver
G4O42_RS01425	COG3173	Aminoglycoside phosphotransferase
G4O42_RS01440	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
G4O42_RS01445	COG0778	Nitroreductase
G4O42_RS01450	COG0346	lactoylglutathione lyase activity
G4O42_RS01455	COG2259	Doxx family
G4O42_RS01460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G4O42_RS01475	COG3773	Cell wall hydrolase
G4O42_RS01480	COG3540	Alkaline phosphatase
G4O42_RS01485	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G4O42_RS01490	COG0805	protein transport
G4O42_RS01500	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G4O42_RS01505	COG0477	Major facilitator Superfamily
G4O42_RS01510	COG1309	transcriptional regulator
G4O42_RS01515	COG0252	asparaginase activity
G4O42_RS01520	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
G4O42_RS01525	COG1405	negative regulation of cell septum assembly
G4O42_RS01525	COG3012	SEC-C Motif Domain Protein
G4O42_RS01540	COG1595	DNA-templated transcription, initiation
G4O42_RS01545	COG1595	DNA-templated transcription, initiation
G4O42_RS01550	COG1876	peptidase activity
G4O42_RS01555	COG0457	Tetratricopeptide repeat
G4O42_RS01560	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_RS01565	COG0366	Alpha amylase catalytic
G4O42_RS01570	COG0803	Belongs to the bacterial solute-binding protein 9 family
G4O42_RS01575	COG1121	(ABC) transporter
G4O42_RS01580	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G4O42_RS01585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G4O42_RS01590	COG2310	stress, protein
G4O42_RS01595	COG2310	stress, protein
G4O42_RS01600	COG2310	stress, protein
G4O42_RS01605	COG0861	Integral membrane protein TerC family
G4O42_RS01615	COG3853	Toxic anion resistance protein (TelA)
G4O42_RS01620	COG0477	Major facilitator Superfamily
G4O42_RS01625	COG4175	Glycine betaine
G4O42_RS01625	COG0517	IMP dehydrogenase activity
G4O42_RS01630	COG4176	ABC-type proline glycine betaine transport system permease component
G4O42_RS01635	COG2113	Glycine betaine
G4O42_RS01640	COG1473	amidohydrolase
G4O42_RS01645	COG1288	antiporter activity
G4O42_RS01665	COG2814	Major facilitator Superfamily
G4O42_RS01670	COG1846	Transcriptional regulator
G4O42_RS01675	COG1280	lysine exporter protein (LysE YggA)
G4O42_RS01680	COG3403	YqcI/YcgG family
G4O42_RS01685	COG1113	amino acid transport
G4O42_RS01690	COG3665	Urea carboxylase-associated protein
G4O42_RS01705	COG1660	Displays ATPase and GTPase activities
G4O42_RS01710	COG1082	Xylose isomerase domain protein TIM barrel
G4O42_RS01715	COG2271	Major facilitator Superfamily
G4O42_RS01720	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
G4O42_RS01725	COG3458	cephalosporin-C deacetylase activity
G4O42_RS01730	COG3541	Predicted nucleotidyltransferase
G4O42_RS01735	COG0506	proline dehydrogenase activity
G4O42_RS01740	COG1012	belongs to the aldehyde dehydrogenase family
G4O42_RS01745	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G4O42_RS01750	COG2508	Transcriptional regulator
G4O42_RS01760	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G4O42_RS01760	COG1587	Uroporphyrinogen-III synthase
G4O42_RS01765	COG2146	nitrite reductase [NAD(P)H] activity
G4O42_RS01770	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G4O42_RS01775	COG0243	molybdopterin cofactor binding
G4O42_RS01780	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G4O42_RS01785	COG2223	nitrite transmembrane transporter activity
G4O42_RS01790	COG0523	cobalamin synthesis protein
G4O42_RS01795	COG1063	alcohol dehydrogenase
G4O42_RS01800	COG1714	RDD family
G4O42_RS01810	COG2723	6-phospho-beta-galactosidase activity
G4O42_RS01825	COG3209	COG3209 Rhs family protein
G4O42_RS01830	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
G4O42_RS01835	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
G4O42_RS01840	COG1733	regulation of RNA biosynthetic process
G4O42_RS01845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_RS01850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_RS01855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_RS01860	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
G4O42_RS01875	COG2364	Membrane
G4O42_RS01880	COG1126	abc transporter atp-binding protein
G4O42_RS01885	COG0765	amino acid transport
G4O42_RS01895	COG0583	DNA-binding transcription factor activity
G4O42_RS01900	COG0163	prenyltransferase activity
G4O42_RS01905	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
G4O42_RS01920	COG3104	oligopeptide transport
G4O42_RS01925	COG5434	Belongs to the glycosyl hydrolase 28 family
G4O42_RS01935	COG0697	spore germination
G4O42_RS01945	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
G4O42_RS01950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G4O42_RS01955	COG0456	acetyltransferase
G4O42_RS01960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G4O42_RS01965	COG0765	amino acid transport
G4O42_RS01970	COG1126	abc transporter atp-binding protein
G4O42_RS01975	COG1473	amidohydrolase
G4O42_RS01980	COG2079	MmgE PrpD family protein
G4O42_RS01985	COG1136	(ABC) transporter
G4O42_RS01990	COG0577	efflux transmembrane transporter activity
G4O42_RS01995	COG0745	RESPONSE REGULATOR receiver
G4O42_RS02000	COG5002	protein histidine kinase activity
G4O42_RS02000	COG3850	Histidine kinase
G4O42_RS02005	COG0457	Tetratricopeptide repeat
G4O42_RS02020	COG0527	aspartate kinase activity
G4O42_RS02025	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G4O42_RS02030	COG4605	iron ion homeostasis
G4O42_RS02035	COG4604	ABC transporter, ATP-binding protein
G4O42_RS02040	COG4607	ABC-type enterochelin transport system periplasmic component
G4O42_RS02045	COG2814	Major facilitator Superfamily
G4O42_RS02050	COG1309	transcriptional regulator
G4O42_RS02055	COG0778	Nitroreductase
G4O42_RS02060	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
G4O42_RS02065	COG0640	Transcriptional regulator
G4O42_RS02070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G4O42_RS02075	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G4O42_RS02080	COG1012	belongs to the aldehyde dehydrogenase family
G4O42_RS02085	COG4975	Glucose uptake
G4O42_RS02090	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_RS02095	COG4549	nuclear export factor GLE1
G4O42_RS02100	COG1276	copper resistance
G4O42_RS02100	COG2372	response to copper ion
G4O42_RS02105	COG1349	DNA-binding transcription factor activity
G4O42_RS02115	COG2213	PTS system mannitol-specific
G4O42_RS02120	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
G4O42_RS02130	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G4O42_RS02140	COG0561	phosphatase activity
G4O42_RS02150	COG1914	H( )-stimulated, divalent metal cation uptake system
G4O42_RS02160	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
G4O42_RS02165	COG1984	allophanate hydrolase subunit 2
G4O42_RS02170	COG1414	Transcriptional regulator
G4O42_RS02175	COG2755	lipolytic protein G-D-S-L family
G4O42_RS02185	COG2329	Antibiotic biosynthesis monooxygenase
G4O42_RS02190	COG0768	penicillin binding
G4O42_RS02195	COG4989	oxidoreductase activity
G4O42_RS02200	COG3711	transcriptional antiterminator
G4O42_RS02205	COG0318	PFAM AMP-dependent synthetase and ligase
G4O42_RS02210	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_RS02215	COG1917	Cupin 2, conserved barrel domain protein
G4O42_RS02220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G4O42_RS02225	COG3871	stress protein (general stress protein 26)
G4O42_RS02235	COG2814	Major facilitator Superfamily
G4O42_RS02240	COG1522	sequence-specific DNA binding
G4O42_RS02245	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G4O42_RS02245	COG0551	DNA topoisomerase type I activity
G4O42_RS02250	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
G4O42_RS02255	COG3706	GGDEF domain
G4O42_RS02260	COG5298	Protein conserved in bacteria
G4O42_RS02265	COG1215	transferase activity, transferring glycosyl groups
G4O42_RS02275	COG0531	amino acid
G4O42_RS02285	COG0028	Belongs to the TPP enzyme family
G4O42_RS02310	COG0457	Tetratricopeptide repeat
G4O42_RS02335	COG1914	H( )-stimulated, divalent metal cation uptake system
G4O42_RS02345	COG4876	unkown
G4O42_RS02355	COG2076	Multidrug Resistance protein
G4O42_RS02360	COG2217	Heavy metal translocating P-type atpase
G4O42_RS02365	COG3729	General stress protein
G4O42_RS02370	COG0662	Cupin 2, conserved barrel domain protein
G4O42_RS02375	COG2329	Antibiotic biosynthesis monooxygenase
G4O42_RS02380	COG3546	catalase activity
G4O42_RS02385	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G4O42_RS02390	COG3290	protein histidine kinase activity
G4O42_RS02395	COG4565	transcriptional regulatory protein
G4O42_RS02400	COG1301	dicarboxylic acid transport
G4O42_RS02405	COG0628	permease
G4O42_RS02410	COG1131	(ABC) transporter
G4O42_RS02415	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
G4O42_RS02425	COG1960	acyl-CoA dehydrogenase activity
G4O42_RS02440	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
G4O42_RS02445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G4O42_RS02455	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
G4O42_RS02460	COG0513	Belongs to the DEAD box helicase family
G4O42_RS02465	COG3402	PFAM membrane-flanked domain
G4O42_RS02470	COG3428	Bacterial PH domain
G4O42_RS02475	COG0705	Rhomboid family
G4O42_RS02485	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
G4O42_RS02490	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G4O42_RS02495	COG0864	Transcriptional regulator
G4O42_RS02500	COG2337	Toxic component of a toxin-antitoxin (TA) module
G4O42_RS02505	COG1366	Belongs to the anti-sigma-factor antagonist family
G4O42_RS02510	COG1366	Belongs to the anti-sigma-factor antagonist family
G4O42_RS02515	COG2172	sigma factor antagonist activity
G4O42_RS02520	COG2208	phosphoserine phosphatase activity
G4O42_RS02525	COG1366	Belongs to the anti-sigma-factor antagonist family
G4O42_RS02535	COG1191	sigma factor activity
G4O42_RS02540	COG2208	phosphoserine phosphatase activity
G4O42_RS02545	COG2183	response to ionizing radiation
G4O42_RS02610	COG5444	nuclease activity
G4O42_RS02615	COG0457	Tetratricopeptide repeat
G4O42_RS02630	COG0477	Major facilitator Superfamily
G4O42_RS02635	COG1846	Transcriptional regulator
G4O42_RS02645	COG2030	dehydratase
G4O42_RS02660	COG1959	2 iron, 2 sulfur cluster binding
G4O42_RS02665	COG2910	NAD(P)H-binding
G4O42_RS02680	COG1278	Cold shock
G4O42_RS02685	COG1329	Transcriptional regulator
G4O42_RS02690	COG1937	Protein conserved in bacteria
G4O42_RS02695	COG2210	Belongs to the sulfur carrier protein TusA family
G4O42_RS02705	COG0425	Belongs to the sulfur carrier protein TusA family
G4O42_RS02705	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G4O42_RS02710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G4O42_RS02710	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G4O42_RS02715	COG0425	Belongs to the sulfur carrier protein TusA family
G4O42_RS02720	COG0730	response to heat
G4O42_RS02725	COG1794	racemase activity, acting on amino acids and derivatives
G4O42_RS02740	COG3621	Patatin-like phospholipase
G4O42_RS02750	COG0662	Cupin 2, conserved barrel domain protein
G4O42_RS02765	COG0277	FAD linked oxidase domain protein
G4O42_RS02790	COG0662	Cupin 2, conserved barrel domain protein
G4O42_RS02795	COG2318	DinB family
G4O42_RS02830	COG1064	alcohol dehydrogenase
G4O42_RS02835	COG0789	Transcriptional regulator
G4O42_RS02845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G4O42_RS02860	COG2814	Major facilitator Superfamily
G4O42_RS02865	COG1309	transcriptional regulator
G4O42_RS02870	COG0697	spore germination
G4O42_RS02875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G4O42_RS02880	COG5577	PFAM Coat F domain
G4O42_RS02890	COG1063	alcohol dehydrogenase
G4O42_RS02895	COG5577	PFAM Coat F domain
G4O42_RS02905	COG4585	Histidine kinase
G4O42_RS02910	COG2197	response regulator
G4O42_RS02915	COG2409	Drug exporters of the RND superfamily
G4O42_RS02920	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
G4O42_RS02930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G4O42_RS02935	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G4O42_RS02945	COG2814	Major facilitator Superfamily
G4O42_RS02950	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G4O42_RS02960	COG0730	response to heat
G4O42_RS02965	COG0456	acetyltransferase
G4O42_RS02970	COG0789	Transcriptional regulator
G4O42_RS02970	COG4978	Transcriptional regulator
G4O42_RS02975	COG0697	spore germination
G4O42_RS02980	COG1051	belongs to the nudix hydrolase family
G4O42_RS02985	COG2226	methyltransferase
G4O42_RS02990	COG0473	3-isopropylmalate dehydrogenase activity
G4O42_RS02995	COG1802	Transcriptional regulator
G4O42_RS03000	COG1819	glycosyl
G4O42_RS03015	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G4O42_RS03025	COG1388	LysM domain
G4O42_RS03030	COG2814	Major facilitator Superfamily
G4O42_RS03035	COG2188	Transcriptional regulator
G4O42_RS03040	COG2186	Transcriptional regulator
G4O42_RS03045	COG2807	transmembrane transport
G4O42_RS03050	COG2076	Multidrug Resistance protein
G4O42_RS03055	COG2076	Multidrug Resistance protein
G4O42_RS03060	COG1309	transcriptional regulator
G4O42_RS03065	COG0531	amino acid
G4O42_RS03075	COG3832	glyoxalase III activity
G4O42_RS03080	COG0604	alcohol dehydrogenase
G4O42_RS03085	COG2814	Major facilitator Superfamily
G4O42_RS03125	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
G4O42_RS03130	COG0802	atpase or kinase
G4O42_RS03135	COG1214	PFAM Peptidase M22, glycoprotease
G4O42_RS03140	COG0456	acetyltransferase
G4O42_RS03145	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
G4O42_RS03150	COG0488	(ABC) transporter
G4O42_RS03165	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G4O42_RS03170	COG0805	protein transport
G4O42_RS03180	COG1266	CAAX protease self-immunity
G4O42_RS03220	COG0457	Tetratricopeptide repeat
G4O42_RS03225	COG1063	alcohol dehydrogenase
G4O42_RS03230	COG2211	Major facilitator Superfamily
G4O42_RS03235	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G4O42_RS03245	COG1842	Phage shock protein A
G4O42_RS03250	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
G4O42_RS03255	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
G4O42_RS03260	COG4260	virion core protein, lumpy skin disease virus
G4O42_RS03265	COG2755	lipolytic protein G-D-S-L family
G4O42_RS03265	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G4O42_RS03275	COG1595	DNA-templated transcription, initiation
G4O42_RS03280	COG1063	alcohol dehydrogenase
G4O42_RS03285	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
G4O42_RS03290	COG0823	Involved in the tonB-independent uptake of proteins
G4O42_RS03300	COG2132	Multicopper oxidase
G4O42_RS03305	COG1113	amino acid transport
G4O42_RS03310	COG0714	Associated with various cellular activities
G4O42_RS03315	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
G4O42_RS03320	COG1305	Transglutaminase-like
G4O42_RS03345	COG2252	PERMEase
G4O42_RS03350	COG3064	Membrane
G4O42_RS03370	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
G4O42_RS03375	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
G4O42_RS03380	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G4O42_RS03385	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
G4O42_RS03390	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G4O42_RS03405	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
G4O42_RS03415	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
G4O42_RS03420	COG0138	bifunctional purine biosynthesis protein purh
G4O42_RS03425	COG0151	Belongs to the GarS family
G4O42_RS03435	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
G4O42_RS03440	COG1470	cell adhesion involved in biofilm formation
G4O42_RS03445	COG4496	protein, YerC YecD
G4O42_RS03450	COG0069	glutamate synthase activity
G4O42_RS03460	COG0210	DNA helicase
G4O42_RS03470	COG4851	CamS sex pheromone cAM373 precursor
G4O42_RS03475	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G4O42_RS03480	COG1285	pathogenesis
G4O42_RS03485	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G4O42_RS03505	COG1309	transcriptional regulator
G4O42_RS03510	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G4O42_RS03515	COG1597	lipid kinase activity
G4O42_RS03520	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G4O42_RS03530	COG1131	(ABC) transporter
G4O42_RS03570	COG5444	nuclease activity
G4O42_RS03600	COG3546	catalase activity
G4O42_RS03605	COG0454	-acetyltransferase
G4O42_RS03615	COG2323	membrane
G4O42_RS03620	COG2329	Antibiotic biosynthesis monooxygenase
G4O42_RS03625	COG0346	lactoylglutathione lyase activity
G4O42_RS03630	COG1366	Belongs to the anti-sigma-factor antagonist family
G4O42_RS03635	COG5583	Uncharacterized small protein (DUF2292)
G4O42_RS03640	COG0196	riboflavin kinase activity
G4O42_RS03645	COG0670	Belongs to the BI1 family
G4O42_RS03650	COG1846	Transcriptional regulator
G4O42_RS03655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G4O42_RS03665	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G4O42_RS03665	COG2124	cytochrome p450
G4O42_RS03670	COG1368	sulfuric ester hydrolase activity
G4O42_RS03675	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
G4O42_RS03680	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G4O42_RS03685	COG1442	glycosyl transferase family 8
G4O42_RS03690	COG1216	Glycosyl transferase, family 2
G4O42_RS03695	COG1442	glycosyl transferase family 8
G4O42_RS03700	COG2223	nitrite transmembrane transporter activity
G4O42_RS03705	COG0531	amino acid
G4O42_RS03710	COG1012	belongs to the aldehyde dehydrogenase family
G4O42_RS03715	COG0840	transmembrane signaling receptor activity
G4O42_RS03720	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_RS03725	COG0463	Glycosyl transferase, family 2
G4O42_RS03725	COG0457	Tetratricopeptide repeat
G4O42_RS03730	COG0488	(ABC) transporter
G4O42_RS03735	COG0789	Transcriptional regulator
G4O42_RS03740	COG2814	Major facilitator Superfamily
G4O42_RS03745	COG0488	(ABC) transporter
G4O42_RS03750	COG0513	Belongs to the DEAD box helicase family
G4O42_RS03755	COG0456	acetyltransferase
G4O42_RS03760	COG2130	NADP-dependent
G4O42_RS03775	COG3866	Pectate lyase
G4O42_RS03780	COG0471	metal ion transport
G4O42_RS03800	COG3290	protein histidine kinase activity
G4O42_RS03805	COG4565	transcriptional regulatory protein
G4O42_RS03810	COG3181	Tripartite tricarboxylate transporter family receptor
G4O42_RS03815	COG2851	Citrate transporter
G4O42_RS03820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G4O42_RS03825	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
G4O42_RS03835	COG2258	MOSC domain
G4O42_RS03855	COG0024	Methionine aminopeptidase
G4O42_RS03860	COG1263	PTS System
G4O42_RS03860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G4O42_RS03870	COG1368	sulfuric ester hydrolase activity
G4O42_RS03880	COG0071	Belongs to the small heat shock protein (HSP20) family
G4O42_RS03895	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G4O42_RS03895	COG1263	PTS System
G4O42_RS03900	COG0366	Alpha amylase catalytic
G4O42_RS03905	COG2188	Transcriptional regulator
G4O42_RS03910	COG0778	Nitroreductase
G4O42_RS03925	COG0737	Belongs to the 5'-nucleotidase family
G4O42_RS03930	COG0693	protein deglycase activity
G4O42_RS03935	COG1609	Transcriptional regulator
G4O42_RS03950	COG2814	Major facilitator Superfamily
G4O42_RS03960	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G4O42_RS03965	COG4980	gas vesicle protein
G4O42_RS03970	COG1295	ribonuclease BN
G4O42_RS03975	COG0477	Major facilitator Superfamily
G4O42_RS03980	COG0387	Pfam Sodium calcium exchanger
G4O42_RS03990	COG0668	transmembrane transport
G4O42_RS03995	COG0535	radical SAM domain protein
G4O42_RS04005	COG0726	polysaccharide deacetylase
G4O42_RS04025	COG0745	RESPONSE REGULATOR receiver
G4O42_RS04030	COG2205	protein histidine kinase activity
G4O42_RS04035	COG2084	Dehydrogenase
G4O42_RS04045	COG0598	Magnesium transport protein CorA
G4O42_RS04050	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
G4O42_RS04055	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G4O42_RS04070	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G4O42_RS04075	COG4637	Psort location Cytoplasmic, score
G4O42_RS04080	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G4O42_RS04085	COG0022	dehydrogenase e1 component
G4O42_RS04090	COG0508	dehydrogenase complex catalyzes the overall conversion of
G4O42_RS04095	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G4O42_RS04100	COG3284	Transcriptional regulator
G4O42_RS04110	COG1486	melibiose metabolic process
G4O42_RS04115	COG1737	Transcriptional regulator
G4O42_RS04120	COG1263	PTS System
G4O42_RS04120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G4O42_RS04130	COG1132	(ABC) transporter
G4O42_RS04135	COG1132	(ABC) transporter
G4O42_RS04140	COG2259	Doxx family
G4O42_RS04145	COG2514	catechol 2,3-dioxygenase activity
G4O42_RS04155	COG1695	Transcriptional regulator
G4O42_RS04160	COG2249	NAD(P)H dehydrogenase (quinone) activity
G4O42_RS04165	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
G4O42_RS04170	COG0574	Belongs to the PEP-utilizing enzyme family
G4O42_RS04170	COG3848	Pyruvate phosphate dikinase
G4O42_RS04175	COG2732	(Barnase) inhibitor
G4O42_RS04180	COG2318	DinB family
G4O42_RS04185	COG2814	Major facilitator Superfamily
G4O42_RS04190	COG1846	Transcriptional regulator
G4O42_RS04195	COG0392	lysyltransferase activity
G4O42_RS04195	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
G4O42_RS04200	COG0384	phenazine biosynthesis protein PhzF
G4O42_RS04205	COG0778	Nitroreductase
G4O42_RS04220	COG1090	epimerase
G4O42_RS04235	COG2814	Major facilitator Superfamily
G4O42_RS04245	COG3591	Belongs to the peptidase S1B family
G4O42_RS04260	COG3103	Sh3 type 3 domain protein
G4O42_RS04265	COG5658	integral membrane protein
G4O42_RS04270	COG0596	Alpha beta hydrolase
G4O42_RS04275	COG0463	Glycosyl transferase, family 2
G4O42_RS04280	COG4485	Bacterial membrane protein, YfhO
G4O42_RS04285	COG1988	membrane-bound metal-dependent
G4O42_RS04290	COG1194	a g-specific adenine glycosylase
G4O42_RS04300	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_RS04320	COG1132	(ABC) transporter
G4O42_RS04325	COG4129	membrane
G4O42_RS04335	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G4O42_RS04340	COG0735	belongs to the Fur family
G4O42_RS04455	COG3340	Belongs to the peptidase S51 family
G4O42_RS04465	COG0277	FAD linked oxidase domain protein
G4O42_RS04475	COG0747	negative chemotaxis
G4O42_RS04480	COG0601	transmembrane transport
G4O42_RS04485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G4O42_RS04490	COG0444	Belongs to the ABC transporter superfamily
G4O42_RS04495	COG4608	Belongs to the ABC transporter superfamily
G4O42_RS04500	COG0753	catalase activity
G4O42_RS04510	COG1116	anion transmembrane transporter activity
G4O42_RS04515	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G4O42_RS04520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G4O42_RS04540	COG1476	TRANSCRIPTIONal
G4O42_RS04550	COG3382	B3 4 domain protein
G4O42_RS04555	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
G4O42_RS04565	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
G4O42_RS04570	COG0789	Transcriptional regulator
G4O42_RS04575	COG1664	Polymer-forming cytoskeletal
G4O42_RS04580	COG1664	Polymer-forming cytoskeletal
G4O42_RS04585	COG2766	serine protein kinase
G4O42_RS04595	COG1846	Transcriptional regulator
G4O42_RS04600	COG1566	PFAM secretion protein HlyD family protein
G4O42_RS04605	COG2814	Major facilitator Superfamily
G4O42_RS04610	COG0655	NAD(P)H dehydrogenase (quinone) activity
G4O42_RS04625	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
G4O42_RS04630	COG1278	Cold shock
G4O42_RS04635	COG1464	Belongs to the NlpA lipoprotein family
G4O42_RS04640	COG3706	GGDEF domain
G4O42_RS04645	COG1823	symporter activity
G4O42_RS04665	COG5577	PFAM Coat F domain
G4O42_RS04670	COG4085	toxin activity
G4O42_RS04670	COG0737	Belongs to the 5'-nucleotidase family
G4O42_RS04670	COG1525	nuclease
G4O42_RS04675	COG3764	Sortase (surface protein transpeptidase)
G4O42_RS04680	COG0564	pseudouridine synthase activity
G4O42_RS04690	COG0517	IMP dehydrogenase activity
G4O42_RS04695	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G4O42_RS04700	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G4O42_RS04700	COG3153	acetyltransferase
G4O42_RS04705	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G4O42_RS04710	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
G4O42_RS04715	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
G4O42_RS04725	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
G4O42_RS04730	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G4O42_RS04735	COG2203	Gaf domain
G4O42_RS04735	COG4585	Histidine kinase
G4O42_RS04740	COG2197	response regulator
G4O42_RS04745	COG0431	NADPH-dependent FMN reductase
G4O42_RS04760	COG1388	LysM domain
G4O42_RS04760	COG0791	NLP P60 protein
G4O42_RS04765	COG1959	2 iron, 2 sulfur cluster binding
G4O42_RS04770	COG0668	transmembrane transport
G4O42_RS04775	COG2719	SpoVR family
G4O42_RS04780	COG1785	Belongs to the alkaline phosphatase family
G4O42_RS04785	COG0791	NLP P60 protein
G4O42_RS04785	COG1388	LysM domain
G4O42_RS04790	COG0583	DNA-binding transcription factor activity
G4O42_RS04795	COG0372	Belongs to the citrate synthase family
G4O42_RS04800	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_RS04805	COG0531	amino acid
G4O42_RS04810	COG0733	neurotransmitter:sodium symporter activity
G4O42_RS04825	COG1595	DNA-templated transcription, initiation
G4O42_RS04830	COG0204	Acyl-transferase
G4O42_RS04835	COG1253	flavin adenine dinucleotide binding
G4O42_RS04840	COG0789	Transcriptional regulator
G4O42_RS04845	COG0436	Aminotransferase
G4O42_RS04850	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G4O42_RS04855	COG1253	flavin adenine dinucleotide binding
G4O42_RS04860	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G4O42_RS04865	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G4O42_RS04870	COG0584	glycerophosphoryl diester phosphodiesterase
G4O42_RS04880	COG0668	transmembrane transport
G4O42_RS04885	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
G4O42_RS04890	COG0726	polysaccharide deacetylase
G4O42_RS04895	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G4O42_RS04900	COG3226	Transcriptional regulator
G4O42_RS04910	COG0589	response to stress
G4O42_RS04915	COG1132	(ABC) transporter
G4O42_RS04920	COG1132	(ABC) transporter
G4O42_RS04925	COG0702	epimerase
G4O42_RS04940	COG0189	ligase activity
G4O42_RS04945	COG0189	ligase activity
G4O42_RS04960	COG4335	DNA alkylation repair
G4O42_RS04965	COG0561	phosphatase activity
G4O42_RS04970	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G4O42_RS04980	COG0475	glutathione-regulated potassium exporter activity
G4O42_RS04985	COG0490	domain, Protein
G4O42_RS04995	COG1024	Enoyl-CoA hydratase
G4O42_RS05005	COG4152	abc transporter atp-binding protein
G4O42_RS05010	COG1668	transmembrane transport
G4O42_RS05015	COG0420	3'-5' exonuclease activity
G4O42_RS05020	COG4717	serine-type aminopeptidase activity
G4O42_RS05035	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G4O42_RS05070	COG4980	gas vesicle protein
G4O42_RS05085	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
G4O42_RS05090	COG0537	adenosine 5'-monophosphoramidase activity
G4O42_RS05095	COG1131	(ABC) transporter
G4O42_RS05100	COG4473	ABC transporter
G4O42_RS05110	COG1473	amidohydrolase
G4O42_RS05115	COG3069	C4-dicarboxylate transmembrane transporter activity
G4O42_RS05120	COG2329	Antibiotic biosynthesis monooxygenase
G4O42_RS05125	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G4O42_RS05145	COG1309	transcriptional regulator
G4O42_RS05150	COG1511	domain protein
G4O42_RS05155	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G4O42_RS05165	COG1363	Peptidase, m42
G4O42_RS05170	COG1301	dicarboxylic acid transport
G4O42_RS05180	COG1234	tRNA 3'-trailer cleavage
G4O42_RS05185	COG0095	Lipoate-protein ligase
G4O42_RS05190	COG0702	epimerase
G4O42_RS05195	COG0318	PFAM AMP-dependent synthetase and ligase
G4O42_RS05205	COG0501	Belongs to the peptidase M48B family
G4O42_RS05210	COG1404	Belongs to the peptidase S8 family
G4O42_RS05220	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
G4O42_RS05225	COG0406	alpha-ribazole phosphatase activity
G4O42_RS05230	COG0183	Belongs to the thiolase family
G4O42_RS05235	COG0318	PFAM AMP-dependent synthetase and ligase
G4O42_RS05240	COG1268	BioY protein
G4O42_RS05245	COG0840	transmembrane signaling receptor activity
G4O42_RS05250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G4O42_RS05250	COG0723	plastoquinol--plastocyanin reductase activity
G4O42_RS05255	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_RS05265	COG4903	ComK protein
G4O42_RS05275	COG5646	InterPro IPR014922
G4O42_RS05295	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G4O42_RS05310	COG0398	Pfam SNARE associated Golgi protein
G4O42_RS05315	COG0681	Belongs to the peptidase S26 family
G4O42_RS05320	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G4O42_RS05325	COG1846	Transcriptional regulator
G4O42_RS05330	COG3180	Ammonia monooxygenase
G4O42_RS05335	COG2814	Major facilitator Superfamily
G4O42_RS05345	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
G4O42_RS05350	COG2323	membrane
G4O42_RS05365	COG0420	3'-5' exonuclease activity
G4O42_RS05370	COG0419	ATPase involved in DNA repair
G4O42_RS05375	COG1403	HNH endonuclease
G4O42_RS05415	COG0179	Fumarylacetoacetate (FAA) hydrolase
G4O42_RS05430	COG0367	asparagine synthase
G4O42_RS05435	COG1562	ergosterol biosynthetic process
G4O42_RS05440	COG0534	Mate efflux family protein
G4O42_RS05445	COG1917	Cupin 2, conserved barrel domain protein
G4O42_RS05445	COG2207	Transcriptional regulator
G4O42_RS05455	COG2318	DinB family
G4O42_RS05460	COG1279	arginine transmembrane transporter activity
G4O42_RS05465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G4O42_RS05470	COG1357	PFAM Pentapeptide repeats (8 copies)
G4O42_RS05475	COG2153	protein acetylation
G4O42_RS05480	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
G4O42_RS05480	COG0646	methionine synthase
G4O42_RS05490	COG2996	Protein conserved in bacteria
G4O42_RS05500	COG0840	transmembrane signaling receptor activity
G4O42_RS05505	COG2124	cytochrome p450
G4O42_RS05515	COG1307	EDD domain protein, DegV family
G4O42_RS05520	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G4O42_RS05540	COG0561	phosphatase activity
G4O42_RS05545	COG1073	alpha beta
G4O42_RS05550	COG2151	metal-sulfur cluster biosynthetic enzyme
G4O42_RS05560	COG0277	FAD linked oxidase domain protein
G4O42_RS05565	COG2271	Major facilitator Superfamily
G4O42_RS05575	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
G4O42_RS05585	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G4O42_RS05590	COG0505	Belongs to the CarA family
G4O42_RS05595	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
G4O42_RS05600	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G4O42_RS05615	COG2267	carboxylic ester hydrolase activity
G4O42_RS05625	COG1744	ABC transporter substrate-binding protein PnrA-like
G4O42_RS05640	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G4O42_RS05645	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G4O42_RS05650	COG5504	Zn-dependent protease
G4O42_RS05655	COG0444	Belongs to the ABC transporter superfamily
G4O42_RS05660	COG4608	Belongs to the ABC transporter superfamily
G4O42_RS05670	COG0601	transmembrane transport
G4O42_RS05675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G4O42_RS05685	COG0180	Tryptophanyl-tRNA synthetase
G4O42_RS05690	COG4166	transmembrane transport
G4O42_RS05695	COG0601	transmembrane transport
G4O42_RS05700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G4O42_RS05705	COG0444	Belongs to the ABC transporter superfamily
G4O42_RS05710	COG4608	Belongs to the ABC transporter superfamily
G4O42_RS05720	COG0456	acetyltransferase
G4O42_RS05725	COG1393	Belongs to the ArsC family
G4O42_RS05730	COG0861	Integral membrane protein TerC family
G4O42_RS05735	COG4862	establishment of competence for transformation
G4O42_RS05740	COG4469	Competence protein
G4O42_RS05745	COG1164	Oligoendopeptidase f
G4O42_RS05760	COG2346	COG2346, Truncated hemoglobins
G4O42_RS05765	COG0741	lytic transglycosylase activity
G4O42_RS05770	COG4116	CYTH
G4O42_RS05780	COG2357	RelA SpoT domain protein
G4O42_RS05785	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G4O42_RS05790	COG0564	pseudouridine synthase activity
G4O42_RS05800	COG0569	domain protein
G4O42_RS05800	COG0475	glutathione-regulated potassium exporter activity
G4O42_RS05805	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
G4O42_RS05810	COG0352	thiamine-phosphate diphosphorylase activity
G4O42_RS05815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G4O42_RS05820	COG2104	thiamine diphosphate biosynthetic process
G4O42_RS05830	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
G4O42_RS05835	COG0351	phosphomethylpyrimidine kinase
G4O42_RS05840	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
G4O42_RS05895	COG0210	DNA helicase
G4O42_RS05915	COG1131	(ABC) transporter
G4O42_RS05925	COG2153	protein acetylation
G4O42_RS05935	COG2382	esterase
G4O42_RS05940	COG0626	cystathionine gamma-synthase activity
G4O42_RS05945	COG0626	cystathionine gamma-synthase activity
G4O42_RS05975	COG5444	nuclease activity
G4O42_RS05985	COG0346	lactoylglutathione lyase activity
G4O42_RS05990	COG2367	Beta-lactamase
G4O42_RS05995	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
G4O42_RS06000	COG0477	Major facilitator Superfamily
G4O42_RS06005	COG1846	Transcriptional regulator
G4O42_RS06015	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
G4O42_RS06020	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G4O42_RS06025	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
G4O42_RS06030	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G4O42_RS06030	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G4O42_RS06035	COG1447	Phosphotransferase system cellobiose-specific component IIA
G4O42_RS06045	COG1349	DNA-binding transcription factor activity
G4O42_RS06065	COG1285	pathogenesis
G4O42_RS06080	COG2205	protein histidine kinase activity
G4O42_RS06090	COG3383	formate dehydrogenase (NAD+) activity
G4O42_RS06095	COG2427	Protein of unknown function (DUF1641)
G4O42_RS06100	COG2124	cytochrome p450
G4O42_RS06105	COG1819	glycosyl
G4O42_RS06115	COG1587	Uroporphyrinogen-III synthase
G4O42_RS06120	COG0390	transport system, permease component
G4O42_RS06125	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G4O42_RS06130	COG0697	spore germination
G4O42_RS06135	COG4297	protein containing double-stranded beta helix domain
G4O42_RS06145	COG1252	NADH dehydrogenase
G4O42_RS06155	COG2211	Major facilitator Superfamily
G4O42_RS06160	COG1609	Transcriptional regulator
G4O42_RS06165	COG0246	Mannitol dehydrogenase
G4O42_RS06170	COG2721	sulfolactate sulfo-lyase activity
G4O42_RS06175	COG0745	RESPONSE REGULATOR receiver
G4O42_RS06180	COG2205	protein histidine kinase activity
G4O42_RS06180	COG2770	Histidine kinase
G4O42_RS06200	COG4585	Histidine kinase
G4O42_RS06205	COG2197	response regulator
G4O42_RS06240	COG0730	response to heat
G4O42_RS06245	COG2318	DinB family
G4O42_RS06250	COG0457	Tetratricopeptide repeat
G4O42_RS06260	COG5632	N-Acetylmuramoyl-L-alanine amidase
G4O42_RS06260	COG3409	Peptidoglycan-binding domain 1 protein
G4O42_RS06260	COG1388	LysM domain
G4O42_RS06270	COG4195	phage-related replication protein
G4O42_RS06275	COG2856	Zn peptidase
G4O42_RS06280	COG1396	sequence-specific DNA binding
G4O42_RS06290	COG1522	sequence-specific DNA binding
G4O42_RS06295	COG1484	DNA-dependent DNA replication
G4O42_RS06315	COG1595	DNA-templated transcription, initiation
G4O42_RS06320	COG5484	DNA packaging
G4O42_RS06320	COG3728	DNA packaging
G4O42_RS06325	COG1783	phage Terminase large subunit
G4O42_RS06330	COG5518	Phage portal protein
G4O42_RS06335	COG0338	D12 class N6 adenine-specific DNA methyltransferase
G4O42_RS06340	COG4653	Phage capsid family
G4O42_RS06390	COG5412	phage tail tape measure protein
G4O42_RS06390	COG3953	SLT domain
G4O42_RS06390	COG5412	phage tail tape measure protein
G4O42_RS06390	COG3953	SLT domain
G4O42_RS06390	COG3953	SLT domain
G4O42_RS06390	COG5412	phage tail tape measure protein
G4O42_RS06395	COG1652	LysM domain
G4O42_RS06400	COG4193	domain, Protein
G4O42_RS06410	COG3628	GPW Gp25 family protein
G4O42_RS06415	COG3299	homolog of phage Mu protein gp47
G4O42_RS06420	COG3778	Protein conserved in bacteria
G4O42_RS06460	COG5632	N-Acetylmuramoyl-L-alanine amidase
G4O42_RS06460	COG3409	Peptidoglycan-binding domain 1 protein
G4O42_RS06475	COG0306	phosphate transporter
G4O42_RS06480	COG1392	Phosphate transport regulator
G4O42_RS06485	COG0531	amino acid
G4O42_RS06490	COG0346	lactoylglutathione lyase activity
G4O42_RS06495	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G4O42_RS06500	COG0463	Glycosyl transferase, family 2
G4O42_RS06510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G4O42_RS06515	COG0477	Major facilitator Superfamily
G4O42_RS06520	COG2362	D-Aminopeptidase
G4O42_RS06525	COG0601	transmembrane transport
G4O42_RS06530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G4O42_RS06535	COG0444	Belongs to the ABC transporter superfamily
G4O42_RS06540	COG4166	transmembrane transport
G4O42_RS06545	COG1619	proteins homologs of microcin C7 resistance protein MccF
G4O42_RS06550	COG4948	Mandelate Racemase Muconate Lactonizing
G4O42_RS06555	COG0791	NLP P60 protein
G4O42_RS06560	COG4608	Belongs to the ABC transporter superfamily
G4O42_RS06565	COG2706	6-phosphogluconolactonase activity
G4O42_RS06570	COG1834	amidinotransferase
G4O42_RS06575	COG1607	acyl-coa hydrolase
G4O42_RS06580	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G4O42_RS06585	COG2076	Multidrug Resistance protein
G4O42_RS06590	COG2076	Multidrug Resistance protein
G4O42_RS06595	COG0788	formyltetrahydrofolate deformylase activity
G4O42_RS06600	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
G4O42_RS06610	COG1764	response to oxidative stress
G4O42_RS06615	COG1846	Transcriptional regulator
G4O42_RS06620	COG1764	response to oxidative stress
G4O42_RS06635	COG0457	Tetratricopeptide repeat
G4O42_RS06635	COG0463	Glycosyl transferase, family 2
G4O42_RS06655	COG1404	Belongs to the peptidase S8 family
G4O42_RS06660	COG1366	Belongs to the anti-sigma-factor antagonist family
G4O42_RS06665	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
G4O42_RS06670	COG1122	ATPase activity
G4O42_RS06675	COG4721	ABC-type cobalt transport system, permease component
G4O42_RS06680	COG1388	LysM domain
G4O42_RS06680	COG3858	chitin binding
G4O42_RS06695	COG2239	Acts as a magnesium transporter
G4O42_RS06700	COG0789	Transcriptional regulator
G4O42_RS06715	COG1846	Transcriptional regulator
G4O42_RS06720	COG0726	polysaccharide deacetylase
G4O42_RS06725	COG3285	dna ligase
G4O42_RS06725	COG1793	dna ligase
G4O42_RS06730	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
G4O42_RS06735	COG0586	Pfam SNARE associated Golgi protein
G4O42_RS06740	COG0861	Integral membrane protein TerC family
G4O42_RS06745	COG1191	sigma factor activity
G4O42_RS06770	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G4O42_RS06775	COG2323	membrane
G4O42_RS06785	COG3594	Acyltransferase
G4O42_RS06790	COG5002	protein histidine kinase activity
G4O42_RS06795	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G4O42_RS06810	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G4O42_RS06815	COG0436	Aminotransferase
G4O42_RS06845	COG3852	Histidine kinase
G4O42_RS06850	COG1846	Transcriptional regulator
G4O42_RS06855	COG1360	Flagellar Motor Protein
G4O42_RS06860	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
G4O42_RS06865	COG0542	response to heat
G4O42_RS06870	COG3949	Membrane
G4O42_RS06885	COG0720	synthase
G4O42_RS06890	COG0602	queuosine metabolic process
G4O42_RS06905	COG1733	regulation of RNA biosynthetic process
G4O42_RS06910	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_RS06925	COG4873	Protein conserved in bacteria
G4O42_RS06935	COG3773	Cell wall hydrolase
G4O42_RS06940	COG2244	polysaccharide biosynthetic process
G4O42_RS06945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G4O42_RS06950	COG2217	Heavy metal translocating P-type atpase
G4O42_RS06955	COG0006	proline dipeptidase activity
G4O42_RS06960	COG1609	Transcriptional regulator
G4O42_RS06965	COG3711	transcriptional antiterminator
G4O42_RS06970	COG1263	PTS System
G4O42_RS06970	COG2190	(PTS) system
G4O42_RS06970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G4O42_RS06975	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G4O42_RS06980	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G4O42_RS06990	COG1533	DNA photolyase activity
G4O42_RS06995	COG0840	transmembrane signaling receptor activity
G4O42_RS07000	COG2084	Dehydrogenase
G4O42_RS07005	COG2340	Cysteine-rich secretory protein family
G4O42_RS07010	COG0768	penicillin binding
G4O42_RS07015	COG4191	Histidine kinase
G4O42_RS07020	COG0436	Aminotransferase
G4O42_RS07030	COG0835	chemotaxis
G4O42_RS07030	COG0784	Response regulator, receiver
G4O42_RS07040	COG2814	Major facilitator Superfamily
G4O42_RS07045	COG1376	ErfK ybiS ycfS ynhG family protein
G4O42_RS07050	COG1408	metallophosphoesterase
G4O42_RS07055	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_RS07065	COG2200	EAL domain
G4O42_RS07070	COG4703	Protein of unknown function (DUF1797)
G4O42_RS07075	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
G4O42_RS07085	COG0517	IMP dehydrogenase activity
G4O42_RS07090	COG0583	DNA-binding transcription factor activity
G4O42_RS07095	COG0716	FMN binding
G4O42_RS07105	COG0716	FMN binding
G4O42_RS07125	COG0668	transmembrane transport
G4O42_RS07130	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G4O42_RS07150	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
G4O42_RS07155	COG0303	'Molybdopterin
G4O42_RS07160	COG1763	Mo-molybdopterin cofactor biosynthetic process
G4O42_RS07165	COG0314	molybdopterin synthase activity
G4O42_RS07170	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
G4O42_RS07180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G4O42_RS07185	COG1136	(ABC) transporter
G4O42_RS07190	COG0577	efflux transmembrane transporter activity
G4O42_RS07195	COG1349	DNA-binding transcription factor activity
G4O42_RS07200	COG1105	Belongs to the carbohydrate kinase PfkB family
G4O42_RS07205	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G4O42_RS07205	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G4O42_RS07205	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G4O42_RS07210	COG0681	Belongs to the peptidase S26 family
G4O42_RS07220	COG0488	(ABC) transporter
G4O42_RS07225	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G4O42_RS07230	COG2309	aminopeptidase activity
G4O42_RS07240	COG1077	Cell shape determining protein MreB Mrl
G4O42_RS07245	COG2002	toxin-antitoxin pair type II binding
G4O42_RS07250	COG3852	Histidine kinase
G4O42_RS07255	COG2105	PFAM AIG2 family protein
G4O42_RS07255	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
G4O42_RS07260	COG0569	domain protein
G4O42_RS07270	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
G4O42_RS07280	COG0561	phosphatase activity
G4O42_RS07285	COG0242	peptide deformylase activity
G4O42_RS07295	COG0497	DNA recombination
G4O42_RS07300	COG2070	2-Nitropropane dioxygenase
G4O42_RS07300	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
G4O42_RS07305	COG3321	synthase
G4O42_RS07305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_RS07305	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_RS07305	COG4221	oxidoreductase activity
G4O42_RS07310	COG4221	oxidoreductase activity
G4O42_RS07310	COG3321	synthase
G4O42_RS07310	COG0300	oxidoreductase activity
G4O42_RS07310	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G4O42_RS07315	COG4221	oxidoreductase activity
G4O42_RS07315	COG3321	synthase
G4O42_RS07315	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_RS07315	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_RS07320	COG4221	oxidoreductase activity
G4O42_RS07320	COG3321	synthase
G4O42_RS07320	COG0300	oxidoreductase activity
G4O42_RS07320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G4O42_RS07325	COG4221	oxidoreductase activity
G4O42_RS07325	COG3321	synthase
G4O42_RS07325	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G4O42_RS07325	COG0300	oxidoreductase activity
G4O42_RS07330	COG4221	oxidoreductase activity
G4O42_RS07330	COG3321	synthase
G4O42_RS07330	COG0300	oxidoreductase activity
G4O42_RS07330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G4O42_RS07335	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_RS07335	COG3321	synthase
G4O42_RS07335	COG4221	oxidoreductase activity
G4O42_RS07335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_RS07340	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G4O42_RS07345	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G4O42_RS07350	COG0022	dehydrogenase e1 component
G4O42_RS07355	COG0508	dehydrogenase complex catalyzes the overall conversion of
G4O42_RS07360	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G4O42_RS07365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G4O42_RS07380	COG1982	Orn Lys Arg decarboxylase major
G4O42_RS07400	COG0483	inositol monophosphate 1-phosphatase activity
G4O42_RS07410	COG3227	Zinc metalloprotease (Elastase)
G4O42_RS07445	COG4896	Protein conserved in bacteria
G4O42_RS07455	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
G4O42_RS07460	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G4O42_RS07465	COG2066	Belongs to the glutaminase family
G4O42_RS07475	COG0772	Belongs to the SEDS family
G4O42_RS07480	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
G4O42_RS07495	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G4O42_RS07495	COG2010	Cytochrome c
G4O42_RS07500	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G4O42_RS07505	COG1845	cytochrome c oxidase, subunit III
G4O42_RS07510	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
G4O42_RS07515	COG3336	cytochrome c oxidase
G4O42_RS07525	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
G4O42_RS07530	COG2340	Cysteine-rich secretory protein family
G4O42_RS07545	COG3679	Belongs to the UPF0342 family
G4O42_RS07555	COG0742	ribosomal rna small subunit methyltransferase
G4O42_RS07565	COG3314	Sporulation integral membrane protein YlbJ
G4O42_RS07570	COG1752	Esterase of the alpha-beta hydrolase superfamily
G4O42_RS07575	COG3480	Lon protease (S16) C-terminal proteolytic domain
G4O42_RS07585	COG1399	metal-binding, possibly nucleic acid-binding protein
G4O42_RS07605	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G4O42_RS07625	COG4839	cell division protein FtsL
G4O42_RS07635	COG0768	penicillin binding
G4O42_RS07655	COG0772	Belongs to the SEDS family
G4O42_RS07670	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
G4O42_RS07675	COG0849	cell division
G4O42_RS07680	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
G4O42_RS07685	COG4412	M6 family metalloprotease domain protein
G4O42_RS07685	COG1404	Belongs to the peptidase S8 family
G4O42_RS07695	COG1191	sigma factor activity
G4O42_RS07700	COG1191	sigma factor activity
G4O42_RS07705	COG1119	ATPase activity
G4O42_RS07710	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G4O42_RS07715	COG1873	PFAM PRC-barrel domain
G4O42_RS07725	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
G4O42_RS07735	COG0762	integral membrane protein
G4O42_RS07740	COG2302	S4 RNA-binding domain
G4O42_RS07745	COG3599	regulation of cell shape
G4O42_RS07750	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
G4O42_RS07755	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
G4O42_RS07765	COG0564	pseudouridine synthase activity
G4O42_RS07775	COG2233	PERMEase
G4O42_RS07785	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G4O42_RS07790	COG0505	Belongs to the CarA family
G4O42_RS07795	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
G4O42_RS07810	COG0284	orotidine-5'-phosphate decarboxylase activity
G4O42_RS07815	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
G4O42_RS07825	COG0306	phosphate transporter
G4O42_RS07840	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G4O42_RS07845	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
G4O42_RS07850	COG1648	precorrin-2 dehydrogenase activity
G4O42_RS07860	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
G4O42_RS07865	COG1561	YicC-like family, N-terminal region
G4O42_RS07875	COG0194	GDP metabolic process
G4O42_RS07885	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
G4O42_RS07890	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
G4O42_RS07895	COG0242	peptide deformylase activity
G4O42_RS07905	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G4O42_RS07905	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
G4O42_RS07915	COG0631	protein serine/threonine phosphatase activity
G4O42_RS07920	COG2815	serine threonine protein kinase
G4O42_RS07920	COG0515	serine threonine protein kinase
G4O42_RS07930	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
G4O42_RS07935	COG1564	THIamine pyrophosphokinase
G4O42_RS07950	COG1302	Protein conserved in bacteria
G4O42_RS07955	COG1461	Dihydroxyacetone kinase
G4O42_RS07960	COG1760	l-serine dehydratase
G4O42_RS07965	COG1760	l-serine dehydratase
G4O42_RS07970	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G4O42_RS07985	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
G4O42_RS07990	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_RS08005	COG1196	nuclear chromosome segregation
G4O42_RS08010	COG0552	protein localization to endoplasmic reticulum
G4O42_RS08025	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G4O42_RS08035	COG1837	Belongs to the UPF0109 family
G4O42_RS08060	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
G4O42_RS08075	COG2257	FlhB HrpN YscU SpaS Family
G4O42_RS08085	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
G4O42_RS08090	COG0758	DNA mediated transformation
G4O42_RS08095	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G4O42_RS08105	COG4974	Belongs to the 'phage' integrase family
G4O42_RS08125	COG1815	bacterial-type flagellum-dependent cell motility
G4O42_RS08130	COG1558	bacterial-type flagellum-dependent cell motility
G4O42_RS08135	COG1677	Flagellar hook-basal body complex protein FliE
G4O42_RS08140	COG1766	The M ring may be actively involved in energy transduction
G4O42_RS08145	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G4O42_RS08150	COG1317	bacterial-type flagellum organization
G4O42_RS08155	COG1157	protein secretion by the type III secretion system
G4O42_RS08160	COG2882	bacterial-type flagellum organization
G4O42_RS08165	COG3334	PFAM MgtE intracellular
G4O42_RS08170	COG3144	bacterial-type flagellum assembly
G4O42_RS08175	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
G4O42_RS08180	COG4786	Flagellar basal body rod
G4O42_RS08185	COG1582	Flagellar protein (FlbD)
G4O42_RS08190	COG1580	Controls the rotational direction of flagella during chemotaxis
G4O42_RS08195	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G4O42_RS08200	COG1776	CheC inhibitor of MCP methylation
G4O42_RS08200	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G4O42_RS08205	COG2201	protein-glutamate methylesterase activity
G4O42_RS08210	COG3190	flagellar
G4O42_RS08215	COG1338	Plays a role in the flagellum-specific transport system
G4O42_RS08220	COG1987	bacterial-type flagellum assembly
G4O42_RS08225	COG1684	flagellar biosynthetic protein fliR
G4O42_RS08230	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
G4O42_RS08235	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
G4O42_RS08240	COG1419	protein localization to endoplasmic reticulum
G4O42_RS08245	COG0455	bacterial-type flagellum organization
G4O42_RS08250	COG2201	protein-glutamate methylesterase activity
G4O42_RS08255	COG0643	Histidine kinase
G4O42_RS08255	COG2198	Histidine kinase
G4O42_RS08260	COG0835	chemotaxis
G4O42_RS08265	COG1776	CheC inhibitor of MCP methylation
G4O42_RS08275	COG1191	sigma factor activity
G4O42_RS08305	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G4O42_RS08310	COG4589	Belongs to the CDS family
G4O42_RS08320	COG0750	zinc metalloprotease
G4O42_RS08330	COG2176	DNA-directed DNA polymerase activity
G4O42_RS08340	COG0195	Participates in both transcription termination and antitermination
G4O42_RS08345	COG2740	Nucleic-acid-binding protein implicated in transcription termination
G4O42_RS08350	COG1358	cellular component organization or biogenesis
G4O42_RS08360	COG1550	Protein conserved in bacteria
G4O42_RS08375	COG0196	riboflavin kinase activity
G4O42_RS08390	COG0726	polysaccharide deacetylase
G4O42_RS08395	COG0612	Peptidase, M16
G4O42_RS08400	COG1873	PFAM PRC-barrel domain
G4O42_RS08405	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G4O42_RS08410	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
G4O42_RS08415	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
G4O42_RS08420	COG0527	aspartate kinase activity
G4O42_RS08430	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
G4O42_RS08435	COG0740	serine-type endopeptidase activity
G4O42_RS08445	COG4980	gas vesicle protein
G4O42_RS08445	COG1674	ftsk spoiiie
G4O42_RS08450	COG2188	Transcriptional regulator
G4O42_RS08455	COG2814	Major facilitator Superfamily
G4O42_RS08460	COG1846	Transcriptional regulator
G4O42_RS08465	COG1033	growth of symbiont in host cell
G4O42_RS08465	COG2409	Drug exporters of the RND superfamily
G4O42_RS08470	COG0612	Peptidase, M16
G4O42_RS08475	COG0612	Peptidase, M16
G4O42_RS08480	COG0300	oxidoreductase activity
G4O42_RS08495	COG1426	Protein conserved in bacteria
G4O42_RS08500	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G4O42_RS08515	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G4O42_RS08525	COG1692	metallophosphoesterase
G4O42_RS08530	COG2359	stage V sporulation protein S
G4O42_RS08550	COG4550	Control of competence regulator ComK, YlbF/YmcA
G4O42_RS08595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G4O42_RS08600	COG3425	synthase
G4O42_RS08605	COG1024	Enoyl-CoA hydratase
G4O42_RS08610	COG1024	Enoyl-CoA hydratase
G4O42_RS08615	COG0300	oxidoreductase activity
G4O42_RS08615	COG0318	PFAM AMP-dependent synthetase and ligase
G4O42_RS08615	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_RS08615	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_RS08615	COG3321	synthase
G4O42_RS08620	COG3321	synthase
G4O42_RS08620	COG0300	oxidoreductase activity
G4O42_RS08620	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G4O42_RS08620	COG4221	oxidoreductase activity
G4O42_RS08625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_RS08625	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_RS08625	COG3321	synthase
G4O42_RS08625	COG3321	synthase
G4O42_RS08625	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G4O42_RS08625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G4O42_RS08625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_RS08625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G4O42_RS08625	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_RS08625	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G4O42_RS08630	COG4221	oxidoreductase activity
G4O42_RS08630	COG3321	synthase
G4O42_RS08630	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_RS08630	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_RS08635	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
G4O42_RS08635	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G4O42_RS08635	COG3321	synthase
G4O42_RS08635	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G4O42_RS08640	COG2124	cytochrome p450
G4O42_RS08645	COG3209	COG3209 Rhs family protein
G4O42_RS08650	COG3619	membrane
G4O42_RS08660	COG1404	Belongs to the peptidase S8 family
G4O42_RS08670	COG4195	phage-related replication protein
G4O42_RS08675	COG1764	response to oxidative stress
G4O42_RS08685	COG2076	Multidrug Resistance protein
G4O42_RS08725	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G4O42_RS08730	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G4O42_RS08735	COG4112	unkown
G4O42_RS08740	COG0860	N-Acetylmuramoyl-L-alanine amidase
G4O42_RS08750	COG0464	growth
G4O42_RS08755	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G4O42_RS08760	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
G4O42_RS08765	COG0789	Transcriptional regulator
G4O42_RS08770	COG0174	glutamine synthetase
G4O42_RS08810	COG2211	Major facilitator Superfamily
G4O42_RS08815	COG3507	Belongs to the glycosyl hydrolase 43 family
G4O42_RS08830	COG1070	Carbohydrate kinase
G4O42_RS08835	COG3848	Pyruvate phosphate dikinase
G4O42_RS08835	COG0574	Belongs to the PEP-utilizing enzyme family
G4O42_RS08860	COG1064	alcohol dehydrogenase
G4O42_RS08865	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
G4O42_RS08865	COG4451	ribulose bisphosphate carboxylase, small
G4O42_RS08910	COG3397	chitin binding
G4O42_RS08930	COG5434	Belongs to the glycosyl hydrolase 28 family
G4O42_RS08935	COG0756	dUTP diphosphatase activity
G4O42_RS08940	COG4195	phage-related replication protein
G4O42_RS08975	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G4O42_RS08985	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
G4O42_RS09005	COG0785	Cytochrome C biogenesis protein
G4O42_RS09010	COG2201	protein-glutamate methylesterase activity
G4O42_RS09015	COG4846	Membrane protein involved in cytochrome C biogenesis
G4O42_RS09025	COG0071	Belongs to the small heat shock protein (HSP20) family
G4O42_RS09040	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
G4O42_RS09045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G4O42_RS09065	COG0824	Thioesterase
G4O42_RS09075	COG4841	protein insertion into membrane
G4O42_RS09085	COG1832	CoA-binding protein
G4O42_RS09090	COG0187	DNA topoisomerase II activity
G4O42_RS09095	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
G4O42_RS09105	COG1115	amino acid carrier protein
G4O42_RS09115	COG1063	alcohol dehydrogenase
G4O42_RS09120	COG0800	Aldolase
G4O42_RS09125	COG1312	Catalyzes the dehydration of D-mannonate
G4O42_RS09130	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_RS09135	COG1609	Transcriptional regulator
G4O42_RS09140	COG2271	Major facilitator Superfamily
G4O42_RS09185	COG2205	protein histidine kinase activity
G4O42_RS09190	COG0745	RESPONSE REGULATOR receiver
G4O42_RS09200	COG3507	Belongs to the glycosyl hydrolase 43 family
G4O42_RS09225	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_RS09230	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G4O42_RS09235	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
G4O42_RS09240	COG2610	gluconate transmembrane transporter activity
G4O42_RS09245	COG2124	cytochrome p450
G4O42_RS09265	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G4O42_RS09275	COG2246	polysaccharide biosynthetic process
G4O42_RS09285	COG0586	Pfam SNARE associated Golgi protein
G4O42_RS09290	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G4O42_RS09295	COG1024	Enoyl-CoA hydratase
G4O42_RS09300	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G4O42_RS09305	COG0511	ligase activity, forming carbon-carbon bonds
G4O42_RS09310	COG0439	Biotin carboxylase
G4O42_RS09315	COG0318	PFAM AMP-dependent synthetase and ligase
G4O42_RS09320	COG1960	acyl-CoA dehydrogenase activity
G4O42_RS09325	COG1649	PFAM Uncharacterised BCR, COG1649
G4O42_RS09335	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
G4O42_RS09335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_RS09340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_RS09345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_RS09350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_RS09355	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_RS09360	COG2027	D-alanyl-D-alanine carboxypeptidase
G4O42_RS09365	COG2017	converts alpha-aldose to the beta-anomer
G4O42_RS09370	COG0534	Mate efflux family protein
G4O42_RS09385	COG0582	viral genome integration into host DNA
G4O42_RS09390	COG0166	Belongs to the GPI family
G4O42_RS09395	COG0405	Gamma-glutamyltransferase
G4O42_RS09400	COG2814	Major facilitator Superfamily
G4O42_RS09405	COG0640	Transcriptional regulator
G4O42_RS09410	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
G4O42_RS09420	COG0604	alcohol dehydrogenase
G4O42_RS09425	COG0493	'glutamate synthase
G4O42_RS09430	COG0067	glutamate synthase
G4O42_RS09430	COG0069	glutamate synthase activity
G4O42_RS09430	COG0070	glutamate synthase
G4O42_RS09435	COG0583	DNA-binding transcription factor activity
G4O42_RS09440	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
G4O42_RS09455	COG0300	oxidoreductase activity
G4O42_RS09460	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
G4O42_RS09470	COG2814	Major facilitator Superfamily
G4O42_RS09475	COG1070	Carbohydrate kinase
G4O42_RS09480	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G4O42_RS09485	COG0243	molybdopterin cofactor binding
G4O42_RS09515	COG5444	nuclease activity
G4O42_RS09520	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G4O42_RS09525	COG0662	Cupin 2, conserved barrel domain protein
G4O42_RS09525	COG2207	Transcriptional regulator
G4O42_RS09530	COG1309	transcriptional regulator
G4O42_RS09535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G4O42_RS09545	COG0640	Transcriptional regulator
G4O42_RS09550	COG0741	lytic transglycosylase activity
G4O42_RS09555	COG2322	membrane
G4O42_RS09570	COG1619	proteins homologs of microcin C7 resistance protein MccF
G4O42_RS09580	COG1388	LysM domain
G4O42_RS09580	COG3584	3D domain protein
G4O42_RS09585	COG0514	ATP-dependent DNA helicase (RecQ)
G4O42_RS09595	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G4O42_RS09600	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
G4O42_RS09615	COG0071	Belongs to the small heat shock protein (HSP20) family
G4O42_RS09645	COG1012	belongs to the aldehyde dehydrogenase family
G4O42_RS09650	COG1657	PFAM Prenyltransferase squalene oxidase
G4O42_RS09655	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
G4O42_RS09660	COG0733	neurotransmitter:sodium symporter activity
G4O42_RS09665	COG0385	Bile acid
G4O42_RS09670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G4O42_RS09675	COG0508	dehydrogenase complex catalyzes the overall conversion of
G4O42_RS09685	COG4548	von Willebrand factor, type A
G4O42_RS09690	COG0714	Associated with various cellular activities
G4O42_RS09695	COG2032	superoxide dismutase activity
G4O42_RS09700	COG1388	LysM domain
G4O42_RS09700	COG0791	NLP P60 protein
G4O42_RS09705	COG1819	glycosyl
G4O42_RS09710	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
G4O42_RS09715	COG0534	Mate efflux family protein
G4O42_RS09720	COG1366	Belongs to the anti-sigma-factor antagonist family
G4O42_RS09725	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G4O42_RS09730	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G4O42_RS09740	COG2962	Rard protein
G4O42_RS09755	COG1942	4-Oxalocrotonate Tautomerase
G4O42_RS09765	COG1733	regulation of RNA biosynthetic process
G4O42_RS09770	COG0778	Nitroreductase
G4O42_RS09775	COG0400	carboxylic ester hydrolase activity
G4O42_RS09780	COG0346	lactoylglutathione lyase activity
G4O42_RS09790	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G4O42_RS09800	COG2723	6-phospho-beta-galactosidase activity
G4O42_RS09805	COG2188	Transcriptional regulator
G4O42_RS09810	COG3409	Peptidoglycan-binding domain 1 protein
G4O42_RS09810	COG0793	Belongs to the peptidase S41A family
G4O42_RS09815	COG2226	methyltransferase
G4O42_RS09825	COG1876	peptidase activity
G4O42_RS09845	COG0671	phosphoesterase, PA-phosphatase related
G4O42_RS09875	COG1509	lysine 2,3-aminomutase activity
G4O42_RS09880	COG0456	acetyltransferase
G4O42_RS09885	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G4O42_RS09890	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G4O42_RS09895	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
G4O42_RS09900	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G4O42_RS09905	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
G4O42_RS09915	COG0456	acetyltransferase
G4O42_RS09920	COG0463	Glycosyl transferase, family 2
G4O42_RS09935	COG4641	Protein conserved in bacteria
G4O42_RS09945	COG1086	Polysaccharide biosynthesis protein
G4O42_RS09980	COG0457	Tetratricopeptide repeat
G4O42_RS09990	COG3391	amine dehydrogenase activity
G4O42_RS10010	COG5444	nuclease activity
G4O42_RS10015	COG4282	regulation of fungal-type cell wall biogenesis
G4O42_RS10020	COG1525	nuclease
G4O42_RS10025	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G4O42_RS10045	COG1846	Transcriptional regulator
G4O42_RS10050	COG4698	Protein conserved in bacteria
G4O42_RS10055	COG2755	lipolytic protein G-D-S-L family
G4O42_RS10060	COG1999	signal sequence binding
G4O42_RS10070	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
G4O42_RS10075	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
G4O42_RS10080	COG1272	protein, Hemolysin III
G4O42_RS10085	COG0204	Acyl-transferase
G4O42_RS10090	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
G4O42_RS10105	COG2136	Putative SAM-dependent methyltransferase
G4O42_RS10105	COG2521	methyltransferase
G4O42_RS10120	COG1413	lyase activity
G4O42_RS10125	COG1418	mRNA catabolic process
G4O42_RS10130	COG0386	Belongs to the glutathione peroxidase family
G4O42_RS10140	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G4O42_RS10150	COG1278	Cold shock
G4O42_RS10170	COG0328	RNA-DNA hybrid ribonuclease activity
G4O42_RS10175	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
G4O42_RS10180	COG0328	RNA-DNA hybrid ribonuclease activity
G4O42_RS10190	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G4O42_RS10205	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
G4O42_RS10215	COG1755	Isoprenylcysteine carboxyl methyltransferase
G4O42_RS10220	COG3424	synthase
G4O42_RS10240	COG1335	isochorismatase
G4O42_RS10250	COG2233	PERMEase
G4O42_RS10260	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
G4O42_RS10265	COG1199	ATP-dependent helicase activity
G4O42_RS10280	COG0116	Belongs to the methyltransferase superfamily
G4O42_RS10310	COG3359	exonuclease
G4O42_RS10315	COG1205	dead DEAH box helicase
G4O42_RS10315	COG1111	helicase
G4O42_RS10320	COG2190	(PTS) system
G4O42_RS10325	COG0071	Belongs to the small heat shock protein (HSP20) family
G4O42_RS10365	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G4O42_RS10365	COG4499	WXG100 protein secretion system (Wss), protein YukC
G4O42_RS10375	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
G4O42_RS10380	COG3935	DnaD domain protein
G4O42_RS10390	COG0436	Aminotransferase
G4O42_RS10395	COG5353	protein conserved in bacteria
G4O42_RS10405	COG1199	ATP-dependent helicase activity
G4O42_RS10405	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G4O42_RS10435	COG0438	transferase activity, transferring glycosyl groups
G4O42_RS10440	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G4O42_RS10455	COG1694	Mazg nucleotide pyrophosphohydrolase
G4O42_RS10460	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G4O42_RS10475	COG4347	Protein of unknown function (DUF1405)
G4O42_RS10480	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
G4O42_RS10480	COG2010	Cytochrome c
G4O42_RS10485	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
G4O42_RS10490	COG0723	plastoquinol--plastocyanin reductase activity
G4O42_RS10505	COG0457	Tetratricopeptide repeat
G4O42_RS10515	COG0287	Prephenate dehydrogenase
G4O42_RS10550	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G4O42_RS10555	COG4401	Chorismate mutase type I
G4O42_RS10570	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
G4O42_RS10575	COG0105	UTP biosynthetic process
G4O42_RS10580	COG0142	geranyltranstransferase activity
G4O42_RS10590	COG0142	geranyltranstransferase activity
G4O42_RS10605	COG0776	regulation of translation
G4O42_RS10610	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
G4O42_RS10650	COG0539	negative regulation of cytoplasmic translation
G4O42_RS10665	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
G4O42_RS10670	COG2959	enzyme of heme biosynthesis
G4O42_RS10675	COG3409	Peptidoglycan-binding domain 1 protein
G4O42_RS10675	COG3773	Cell wall hydrolase
G4O42_RS10680	COG2339	peptidase activity
G4O42_RS10685	COG0492	ferredoxin-NADP+ reductase activity
G4O42_RS10690	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G4O42_RS10695	COG4862	establishment of competence for transformation
G4O42_RS10700	COG1408	metallophosphoesterase
G4O42_RS10710	COG1388	LysM domain
G4O42_RS10715	COG1266	CAAX protease self-immunity
G4O42_RS10720	COG0514	ATP-dependent DNA helicase (RecQ)
G4O42_RS10725	COG4955	Helix-turn-helix domain
G4O42_RS10730	COG1141	Ferredoxin
G4O42_RS10735	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
G4O42_RS10740	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G4O42_RS10750	COG1595	DNA-templated transcription, initiation
G4O42_RS10755	COG5002	protein histidine kinase activity
G4O42_RS10760	COG0745	RESPONSE REGULATOR receiver
G4O42_RS10765	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G4O42_RS10770	COG1333	cytochrome c biogenesis protein
G4O42_RS10775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G4O42_RS10780	COG1187	pseudouridine synthase activity
G4O42_RS10785	COG0700	Nucleoside recognition
G4O42_RS10790	COG2715	membrane protein required for spore maturation
G4O42_RS10795	COG1686	Belongs to the peptidase S11 family
G4O42_RS10820	COG1547	Domain of unknown function (DUF309)
G4O42_RS10825	COG0456	acetyltransferase
G4O42_RS10840	COG0307	riboflavin synthase, alpha
G4O42_RS10845	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G4O42_RS10845	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G4O42_RS10855	COG0681	Belongs to the peptidase S26 family
G4O42_RS10865	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G4O42_RS10870	COG4086	secreted protein
G4O42_RS10875	COG0019	diaminopimelate decarboxylase activity
G4O42_RS10880	COG0697	spore germination
G4O42_RS10895	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G4O42_RS10915	COG1191	sigma factor activity
G4O42_RS10925	COG1366	Belongs to the anti-sigma-factor antagonist family
G4O42_RS10930	COG1686	Belongs to the peptidase S11 family
G4O42_RS10935	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
G4O42_RS10940	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
G4O42_RS10945	COG4974	Belongs to the 'phage' integrase family
G4O42_RS10955	COG0735	belongs to the Fur family
G4O42_RS10960	COG1300	Membrane
G4O42_RS10975	COG0281	malic enzyme
G4O42_RS10980	COG1757	Na H antiporter
G4O42_RS10985	COG1027	Aspartate ammonia-lyase
G4O42_RS10990	COG0252	asparaginase activity
G4O42_RS10995	COG1396	sequence-specific DNA binding
G4O42_RS11000	COG1379	DNA repair
G4O42_RS11005	COG0494	nUDIX hydrolase
G4O42_RS11015	COG0667	Aldo Keto reductase
G4O42_RS11025	COG1073	alpha beta
G4O42_RS11035	COG4918	Iron-sulphur cluster biosynthesis
G4O42_RS11040	COG0456	acetyltransferase
G4O42_RS11040	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
G4O42_RS11045	COG2329	Antibiotic biosynthesis monooxygenase
G4O42_RS11050	COG0456	acetyltransferase
G4O42_RS11055	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G4O42_RS11070	COG0628	permease
G4O42_RS11080	COG0346	lactoylglutathione lyase activity
G4O42_RS11090	COG3048	D-serine ammonia-lyase activity
G4O42_RS11095	COG0300	oxidoreductase activity
G4O42_RS11100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G4O42_RS11105	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
G4O42_RS11110	COG1024	Enoyl-CoA hydratase
G4O42_RS11115	COG3425	synthase
G4O42_RS11120	COG2124	cytochrome p450
G4O42_RS11125	COG3321	synthase
G4O42_RS11125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G4O42_RS11125	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G4O42_RS11125	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_RS11125	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_RS11130	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_RS11130	COG3321	synthase
G4O42_RS11130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_RS11130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G4O42_RS11130	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G4O42_RS11135	COG3321	synthase
G4O42_RS11135	COG0300	oxidoreductase activity
G4O42_RS11135	COG0318	PFAM AMP-dependent synthetase and ligase
G4O42_RS11135	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_RS11135	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_RS11140	COG0318	PFAM AMP-dependent synthetase and ligase
G4O42_RS11140	COG3321	synthase
G4O42_RS11140	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_RS11140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_RS11140	COG0300	oxidoreductase activity
G4O42_RS11145	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_RS11145	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G4O42_RS11145	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_RS11145	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G4O42_RS11145	COG3321	synthase
G4O42_RS11150	COG0300	oxidoreductase activity
G4O42_RS11150	COG0318	PFAM AMP-dependent synthetase and ligase
G4O42_RS11150	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_RS11150	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_RS11150	COG3321	synthase
G4O42_RS11155	COG3321	synthase
G4O42_RS11155	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G4O42_RS11155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G4O42_RS11155	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_RS11155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_RS11160	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_RS11165	COG0318	PFAM AMP-dependent synthetase and ligase
G4O42_RS11180	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
G4O42_RS11180	COG2070	2-Nitropropane dioxygenase
G4O42_RS11185	COG0250	Participates in transcription elongation, termination and antitermination
G4O42_RS11205	COG0596	Alpha beta hydrolase
G4O42_RS11220	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
G4O42_RS11225	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
G4O42_RS11240	COG0706	membrane insertase activity
G4O42_RS11245	COG2195	Cleaves the N-terminal amino acid of tripeptides
G4O42_RS11250	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G4O42_RS11255	COG0346	lactoylglutathione lyase activity
G4O42_RS11270	COG4129	membrane
G4O42_RS11275	COG1126	abc transporter atp-binding protein
G4O42_RS11280	COG0765	amino acid transport
G4O42_RS11285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G4O42_RS11295	COG1597	lipid kinase activity
G4O42_RS11300	COG0508	dehydrogenase complex catalyzes the overall conversion of
G4O42_RS11305	COG0022	dehydrogenase e1 component
G4O42_RS11310	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G4O42_RS11315	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G4O42_RS11320	COG3426	butyrate kinase activity
G4O42_RS11325	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G4O42_RS11330	COG0280	phosphate acetyltransferase
G4O42_RS11335	COG3290	protein histidine kinase activity
G4O42_RS11335	COG3829	transcription factor binding
G4O42_RS11345	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
G4O42_RS11350	COG2079	MmgE PrpD family protein
G4O42_RS11355	COG0372	Belongs to the citrate synthase family
G4O42_RS11360	COG1960	acyl-CoA dehydrogenase activity
G4O42_RS11365	COG1250	3-hydroxyacyl-CoA dehydrogenase
G4O42_RS11370	COG0183	Belongs to the thiolase family
G4O42_RS11375	COG0584	glycerophosphoryl diester phosphodiesterase
G4O42_RS11380	COG0860	N-Acetylmuramoyl-L-alanine amidase
G4O42_RS11405	COG1902	pentaerythritol trinitrate reductase activity
G4O42_RS11420	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G4O42_RS11425	COG0745	RESPONSE REGULATOR receiver
G4O42_RS11430	COG0750	zinc metalloprotease
G4O42_RS11435	COG0497	DNA recombination
G4O42_RS11445	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
G4O42_RS11455	COG0142	geranyltranstransferase activity
G4O42_RS11465	COG1570	exodeoxyribonuclease VII activity
G4O42_RS11480	COG1302	Protein conserved in bacteria
G4O42_RS11485	COG0439	Biotin carboxylase
G4O42_RS11490	COG0511	ligase activity, forming carbon-carbon bonds
G4O42_RS11530	COG3854	ATPases associated with a variety of cellular activities
G4O42_RS11545	COG0006	proline dipeptidase activity
G4O42_RS11555	COG3872	metal-dependent enzyme
G4O42_RS11565	COG1752	Esterase of the alpha-beta hydrolase superfamily
G4O42_RS11580	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G4O42_RS11600	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G4O42_RS11615	COG1396	sequence-specific DNA binding
G4O42_RS11625	COG0681	Belongs to the peptidase S26 family
G4O42_RS11650	COG4940	Competence protein ComGF
G4O42_RS11660	COG4970	Tfp pilus assembly protein FimT
G4O42_RS11665	COG4537	Required for transformation and DNA binding
G4O42_RS11670	COG1459	type II secretion system
G4O42_RS11675	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G4O42_RS11680	COG0598	Magnesium transport protein CorA
G4O42_RS11685	COG1253	flavin adenine dinucleotide binding
G4O42_RS11690	COG1366	Belongs to the anti-sigma-factor antagonist family
G4O42_RS11700	COG1393	Belongs to the ArsC family
G4O42_RS11710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G4O42_RS11720	COG0011	TIGRFAM Protein of
G4O42_RS11730	COG2866	Carboxypeptidase
G4O42_RS11735	COG1940	carbohydrate kinase activity
G4O42_RS11740	COG4483	Protein conserved in bacteria
G4O42_RS11745	COG1757	Na H antiporter
G4O42_RS11755	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G4O42_RS11770	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
G4O42_RS11775	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G4O42_RS11780	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G4O42_RS11785	COG0581	inorganic phosphate transmembrane transporter activity
G4O42_RS11790	COG0573	inorganic phosphate transmembrane transporter activity
G4O42_RS11795	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
G4O42_RS11805	COG0477	Major facilitator Superfamily
G4O42_RS11810	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
G4O42_RS11815	COG2839	Protein conserved in bacteria
G4O42_RS11820	COG5521	maltodextrose utilization protein MalA
G4O42_RS11825	COG1388	LysM domain
G4O42_RS11835	COG4709	membrane
G4O42_RS11840	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
G4O42_RS11845	COG0735	belongs to the Fur family
G4O42_RS11850	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G4O42_RS11865	COG0513	Belongs to the DEAD box helicase family
G4O42_RS11880	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
G4O42_RS11885	COG2384	SAM-dependent methyltransferase
G4O42_RS11890	COG2010	Cytochrome c
G4O42_RS11895	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G4O42_RS11900	COG0358	DNA primase activity
G4O42_RS11915	COG0517	IMP dehydrogenase activity
G4O42_RS11920	COG0751	glycine-tRNA ligase activity
G4O42_RS11940	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
G4O42_RS11945	COG0295	cytidine deaminase activity
G4O42_RS11950	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
G4O42_RS11960	COG1480	7TM receptor with intracellular HD hydrolase
G4O42_RS11965	COG1702	phosphate starvation-inducible protein PhoH
G4O42_RS11970	COG0561	phosphatase activity
G4O42_RS11985	COG4864	UPF0365 protein
G4O42_RS11990	COG1030	water channel activity
G4O42_RS11995	COG1610	YqeY-like protein
G4O42_RS12005	COG1283	sodium-dependent phosphate transmembrane transporter activity
G4O42_RS12010	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G4O42_RS12015	COG1385	rRNA (uridine-N3-)-methyltransferase activity
G4O42_RS12045	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G4O42_RS12060	COG0860	N-Acetylmuramoyl-L-alanine amidase
G4O42_RS12075	COG1466	dna polymerase III delta subunit
G4O42_RS12090	COG2333	competence protein COMEC
G4O42_RS12090	COG0658	competence protein
G4O42_RS12095	COG2131	deaminase
G4O42_RS12100	COG1555	photosystem II stabilization
G4O42_RS12100	COG1596	polysaccharide export
G4O42_RS12105	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
G4O42_RS12110	COG2226	methyltransferase
G4O42_RS12115	COG0799	negative regulation of ribosome biogenesis
G4O42_RS12120	COG1713	HD superfamily hydrolase involved in NAD metabolism
G4O42_RS12130	COG1534	Rna-binding protein
G4O42_RS12135	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G4O42_RS12140	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
G4O42_RS12145	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
G4O42_RS12155	COG2755	lipolytic protein G-D-S-L family
G4O42_RS12165	COG0398	Pfam SNARE associated Golgi protein
G4O42_RS12190	COG1794	racemase activity, acting on amino acids and derivatives
G4O42_RS12205	COG1733	regulation of RNA biosynthetic process
G4O42_RS12210	COG0656	L-ascorbic acid biosynthetic process
G4O42_RS12240	COG3677	Transposase
G4O42_RS12280	COG5002	protein histidine kinase activity
G4O42_RS12280	COG0642	Histidine kinase
G4O42_RS12285	COG0745	RESPONSE REGULATOR receiver
G4O42_RS12290	COG2311	Membrane
G4O42_RS12300	COG0454	-acetyltransferase
G4O42_RS12305	COG0563	adenylate kinase activity
G4O42_RS12315	COG2814	Major facilitator Superfamily
G4O42_RS12325	COG0456	acetyltransferase
G4O42_RS12330	COG2318	DinB family
G4O42_RS12340	COG0561	phosphatase activity
G4O42_RS12345	COG0561	phosphatase activity
G4O42_RS12355	COG1482	cell wall glycoprotein biosynthetic process
G4O42_RS12360	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G4O42_RS12360	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G4O42_RS12360	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G4O42_RS12365	COG3711	transcriptional antiterminator
G4O42_RS12365	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G4O42_RS12375	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
G4O42_RS12380	COG0583	DNA-binding transcription factor activity
G4O42_RS12385	COG2814	Major facilitator Superfamily
G4O42_RS12390	COG2124	cytochrome p450
G4O42_RS12390	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G4O42_RS12395	COG1309	transcriptional regulator
G4O42_RS12400	COG2226	methyltransferase
G4O42_RS12415	COG2116	formate transmembrane transporter activity
G4O42_RS12420	COG5609	conserved protein (DUF2294)
G4O42_RS12425	COG3383	formate dehydrogenase (NAD+) activity
G4O42_RS12430	COG2427	Protein of unknown function (DUF1641)
G4O42_RS12440	COG0626	cystathionine gamma-synthase activity
G4O42_RS12445	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G4O42_RS12470	COG0768	penicillin binding
G4O42_RS12495	COG4122	O-methyltransferase activity
G4O42_RS12500	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
G4O42_RS12525	COG0628	permease
G4O42_RS12530	COG1126	abc transporter atp-binding protein
G4O42_RS12535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G4O42_RS12540	COG0765	amino acid transport
G4O42_RS12545	COG0765	amino acid transport
G4O42_RS12560	COG3881	PFAM PRC-barrel domain
G4O42_RS12565	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G4O42_RS12570	COG0457	Tetratricopeptide repeat
G4O42_RS12580	COG1104	cysteine desulfurase activity
G4O42_RS12585	COG1959	2 iron, 2 sulfur cluster binding
G4O42_RS12590	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
G4O42_RS12595	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
G4O42_RS12620	COG4991	sh3 domain protein
G4O42_RS12620	COG3103	Sh3 type 3 domain protein
G4O42_RS12620	COG0860	N-Acetylmuramoyl-L-alanine amidase
G4O42_RS12630	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G4O42_RS12640	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
G4O42_RS12640	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
G4O42_RS12645	COG5416	Lipopolysaccharide assembly protein A domain
G4O42_RS12650	COG0490	domain, Protein
G4O42_RS12655	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G4O42_RS12655	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G4O42_RS12665	COG2244	polysaccharide biosynthetic process
G4O42_RS12670	COG2323	membrane
G4O42_RS12680	COG1862	Preprotein translocase
G4O42_RS12720	COG1388	LysM domain
G4O42_RS12730	COG0157	Belongs to the NadC ModD family
G4O42_RS12735	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
G4O42_RS12740	COG1104	cysteine desulfurase activity
G4O42_RS12745	COG1827	regulation of RNA biosynthetic process
G4O42_RS12750	COG0077	Prephenate dehydratase
G4O42_RS12765	COG3290	protein histidine kinase activity
G4O42_RS12770	COG0211	Belongs to the bacterial ribosomal protein bL27 family
G4O42_RS12775	COG2868	ribosomal protein
G4O42_RS12785	COG1994	Peptidase M50
G4O42_RS12790	COG0739	heme binding
G4O42_RS12795	COG2894	cell division
G4O42_RS12800	COG0850	regulation of cytokinetic process
G4O42_RS12805	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
G4O42_RS12815	COG1077	Cell shape determining protein MreB Mrl
G4O42_RS12835	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
G4O42_RS12840	COG0285	dihydrofolate synthase activity
G4O42_RS12845	COG0525	valine-tRNA ligase activity
G4O42_RS12855	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G4O42_RS12860	COG1388	LysM domain
G4O42_RS12870	COG0113	porphobilinogen synthase activity
G4O42_RS12875	COG1587	Uroporphyrinogen-III synthase
G4O42_RS12885	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G4O42_RS12905	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
G4O42_RS12910	COG1067	ATP-dependent peptidase activity
G4O42_RS12910	COG0470	DNA polymerase III
G4O42_RS12925	COG1477	protein flavinylation
G4O42_RS12925	COG0457	Tetratricopeptide repeat
G4O42_RS12940	COG0473	3-isopropylmalate dehydrogenase activity
G4O42_RS12955	COG0440	acetolactate synthase activity
G4O42_RS12960	COG0028	Belongs to the TPP enzyme family
G4O42_RS12985	COG0622	Phosphoesterase
G4O42_RS12990	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
G4O42_RS13000	COG5401	PFAM Sporulation and spore germination
G4O42_RS13010	COG1846	Transcriptional regulator
G4O42_RS13015	COG2197	response regulator
G4O42_RS13020	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G4O42_RS13025	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G4O42_RS13055	COG5444	nuclease activity
G4O42_RS13075	COG5632	N-Acetylmuramoyl-L-alanine amidase
G4O42_RS13080	COG4824	toxin secretion phage lysis holin
G4O42_RS13135	COG5280	Phage tail tape measure protein TP901
G4O42_RS13135	COG3953	SLT domain
G4O42_RS13210	COG5484	DNA packaging
G4O42_RS13220	COG3677	Transposase
G4O42_RS13320	COG1484	DNA-dependent DNA replication
G4O42_RS13325	COG3935	DnaD domain protein
G4O42_RS13330	COG3723	Recombinational DNA repair protein, rece pathway
G4O42_RS13335	COG5377	YqaJ viral recombinase family
G4O42_RS13365	COG3617	BRO family, N-terminal domain
G4O42_RS13390	COG3620	sequence-specific DNA binding
G4O42_RS13395	COG1525	nuclease
G4O42_RS13405	COG2856	Zn peptidase
G4O42_RS13410	COG2197	response regulator
G4O42_RS13415	COG0824	Thioesterase
G4O42_RS13420	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G4O42_RS13425	COG1053	succinate dehydrogenase
G4O42_RS13430	COG2009	succinate dehydrogenase
G4O42_RS13435	COG1719	4-vinyl reductase, 4VR
G4O42_RS13440	COG0527	aspartate kinase activity
G4O42_RS13450	COG3118	belongs to the thioredoxin family
G4O42_RS13455	COG3534	alpha-L-arabinofuranosidase
G4O42_RS13460	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
G4O42_RS13465	COG2086	electron transfer activity
G4O42_RS13470	COG1024	Enoyl-CoA hydratase
G4O42_RS13475	COG1309	transcriptional regulator
G4O42_RS13480	COG0318	PFAM AMP-dependent synthetase and ligase
G4O42_RS13490	COG3766	membrane
G4O42_RS13500	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
G4O42_RS13500	COG1796	DNA polymerase
G4O42_RS13505	COG1286	toxin biosynthetic process
G4O42_RS13520	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G4O42_RS13520	COG0072	phenylalanine-tRNA ligase activity
G4O42_RS13525	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
G4O42_RS13530	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G4O42_RS13540	COG3835	regulator
G4O42_RS13545	COG0277	FAD linked oxidase domain protein
G4O42_RS13550	COG0247	lactate metabolic process
G4O42_RS13555	COG1966	Carbon starvation protein
G4O42_RS13560	COG3534	alpha-L-arabinofuranosidase
G4O42_RS13565	COG0395	ABC-type sugar transport system, permease component
G4O42_RS13570	COG1175	transmembrane transport
G4O42_RS13575	COG1653	transport
G4O42_RS13585	COG0647	UMP catabolic process
G4O42_RS13590	COG0235	Class ii aldolase
G4O42_RS13595	COG1069	ribulokinase activity
G4O42_RS13600	COG2160	L-arabinose isomerase activity
G4O42_RS13605	COG3507	Belongs to the glycosyl hydrolase 43 family
G4O42_RS13610	COG1363	Peptidase, m42
G4O42_RS13620	COG3326	Membrane
G4O42_RS13635	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
G4O42_RS13640	COG1346	cytolysis
G4O42_RS13645	COG1380	Effector of murein hydrolase LrgA
G4O42_RS13650	COG3279	Response regulator of the LytR AlgR family
G4O42_RS13655	COG3275	phosphorelay sensor kinase activity
G4O42_RS13660	COG1011	Hydrolase
G4O42_RS13675	COG0398	Pfam SNARE associated Golgi protein
G4O42_RS13680	COG1484	DNA-dependent DNA replication
G4O42_RS13685	COG3611	Membrane attachment protein
G4O42_RS13700	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G4O42_RS13705	COG1733	regulation of RNA biosynthetic process
G4O42_RS13710	COG2814	Major facilitator Superfamily
G4O42_RS13715	COG0656	L-ascorbic acid biosynthetic process
G4O42_RS13720	COG0237	dephospho-CoA kinase activity
G4O42_RS13725	COG1971	Probably functions as a manganese efflux pump
G4O42_RS13730	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G4O42_RS13735	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G4O42_RS13735	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G4O42_RS13740	COG5002	protein histidine kinase activity
G4O42_RS13745	COG0745	RESPONSE REGULATOR receiver
G4O42_RS13755	COG0538	isocitrate dehydrogenase activity
G4O42_RS13760	COG0372	Belongs to the citrate synthase family
G4O42_RS13790	COG0628	permease
G4O42_RS13795	COG3030	protein affecting phage T7 exclusion by the F plasmid
G4O42_RS13800	COG0469	pyruvate kinase activity
G4O42_RS13820	COG0281	malic enzyme
G4O42_RS13825	COG0587	DNA-directed DNA polymerase activity
G4O42_RS13845	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
G4O42_RS13855	COG4109	DRTGG domain
G4O42_RS13865	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_RS13880	COG0521	Mo-molybdopterin cofactor biosynthetic process
G4O42_RS13890	COG0827	DNA restriction-modification system
G4O42_RS13895	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
G4O42_RS13900	COG3874	Sporulation protein YtfJ
G4O42_RS13910	COG1714	RDD family
G4O42_RS13915	COG0616	signal peptide processing
G4O42_RS13920	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G4O42_RS13925	COG1574	metal-dependent hydrolase with the TIM-barrel fold
G4O42_RS13930	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G4O42_RS13945	COG1104	cysteine desulfurase activity
G4O42_RS13950	COG1114	Component of the transport system for branched-chain amino acids
G4O42_RS13960	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
G4O42_RS13965	COG1309	transcriptional regulator
G4O42_RS13970	COG1956	GAF domain-containing protein
G4O42_RS13975	COG2199	diguanylate cyclase activity
G4O42_RS13975	COG2203	Gaf domain
G4O42_RS13990	COG1012	belongs to the aldehyde dehydrogenase family
G4O42_RS13995	COG4282	regulation of fungal-type cell wall biogenesis
G4O42_RS14040	COG1017	nitric oxide dioxygenase activity
G4O42_RS14040	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G4O42_RS14055	COG0693	protein deglycase activity
G4O42_RS14070	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
G4O42_RS14075	COG1378	Sugar-specific transcriptional regulator TrmB
G4O42_RS14095	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G4O42_RS14100	COG0454	-acetyltransferase
G4O42_RS14105	COG0517	IMP dehydrogenase activity
G4O42_RS14110	COG0123	including yeast histone deacetylase and acetoin utilization protein
G4O42_RS14115	COG1360	Flagellar Motor Protein
G4O42_RS14120	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
G4O42_RS14125	COG1609	Transcriptional regulator
G4O42_RS14130	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
G4O42_RS14130	COG1605	Chorismate mutase
G4O42_RS14135	COG3118	belongs to the thioredoxin family
G4O42_RS14140	COG4980	gas vesicle protein
G4O42_RS14145	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
G4O42_RS14155	COG1674	ftsk spoiiie
G4O42_RS14160	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G4O42_RS14170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G4O42_RS14180	COG1363	Peptidase, m42
G4O42_RS14185	COG5584	Small secreted protein
G4O42_RS14190	COG0281	malic enzyme
G4O42_RS14195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G4O42_RS14210	COG0510	thiamine kinase activity
G4O42_RS14215	COG1597	lipid kinase activity
G4O42_RS14225	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
G4O42_RS14230	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G4O42_RS14235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G4O42_RS14240	COG2252	PERMEase
G4O42_RS14245	COG4473	ABC transporter
G4O42_RS14250	COG1131	(ABC) transporter
G4O42_RS14255	COG1349	DNA-binding transcription factor activity
G4O42_RS14260	COG1187	pseudouridine synthase activity
G4O42_RS14265	COG2244	polysaccharide biosynthetic process
G4O42_RS14270	COG2081	HI0933 family
G4O42_RS14275	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G4O42_RS14285	COG1609	Transcriptional regulator
G4O42_RS14290	COG1653	transport
G4O42_RS14295	COG1175	transmembrane transport
G4O42_RS14300	COG0395	ABC-type sugar transport system, permease component
G4O42_RS14305	COG1486	melibiose metabolic process
G4O42_RS14315	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G4O42_RS14330	COG2202	Pas domain
G4O42_RS14330	COG1366	Belongs to the anti-sigma-factor antagonist family
G4O42_RS14335	COG2814	Major facilitator Superfamily
G4O42_RS14340	COG5522	Integral membrane protein (intg_mem_TP0381)
G4O42_RS14345	COG0577	efflux transmembrane transporter activity
G4O42_RS14350	COG1136	(ABC) transporter
G4O42_RS14355	COG2205	protein histidine kinase activity
G4O42_RS14360	COG0745	RESPONSE REGULATOR receiver
G4O42_RS14365	COG0577	efflux transmembrane transporter activity
G4O42_RS14370	COG1136	(ABC) transporter
G4O42_RS14390	COG1131	(ABC) transporter
G4O42_RS14395	COG1725	Transcriptional regulator
G4O42_RS14405	COG1242	4 iron, 4 sulfur cluster binding
G4O42_RS14410	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
G4O42_RS14420	COG0584	glycerophosphoryl diester phosphodiesterase
G4O42_RS14430	COG2267	carboxylic ester hydrolase activity
G4O42_RS14435	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
G4O42_RS14440	COG1113	amino acid transport
G4O42_RS14445	COG0367	asparagine synthase
G4O42_RS14465	COG1506	peptidase
G4O42_RS14470	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G4O42_RS14475	COG1116	anion transmembrane transporter activity
G4O42_RS14480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G4O42_RS14485	COG0494	nUDIX hydrolase
G4O42_RS14490	COG4824	toxin secretion phage lysis holin
G4O42_RS14495	COG0783	Belongs to the Dps family
G4O42_RS14520	COG0288	reversible hydration of carbon dioxide
G4O42_RS14530	COG1271	oxidase subunit
G4O42_RS14535	COG1294	oxidase, subunit
G4O42_RS14550	COG4948	Mandelate Racemase Muconate Lactonizing
G4O42_RS14560	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
G4O42_RS14565	COG0596	Alpha beta hydrolase
G4O42_RS14575	COG1169	isochorismate synthase
G4O42_RS14580	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
G4O42_RS14585	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
G4O42_RS14710	COG3859	Proton-coupled thiamine transporter YuaJ
G4O42_RS14715	COG2268	Band 7 protein
G4O42_RS14720	COG1585	Membrane protein implicated in regulation of membrane protease activity
G4O42_RS14725	COG2318	DinB family
G4O42_RS14735	COG1454	alcohol dehydrogenase
G4O42_RS14740	COG1012	belongs to the aldehyde dehydrogenase family
G4O42_RS14745	COG1510	regulation of RNA biosynthetic process
G4O42_RS14755	COG0569	domain protein
G4O42_RS14760	COG1705	Flagellar rod assembly protein muramidase FlgJ
G4O42_RS14765	COG1017	nitric oxide dioxygenase activity
G4O42_RS14765	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G4O42_RS14790	COG0628	permease
G4O42_RS14795	COG0673	inositol 2-dehydrogenase activity
G4O42_RS14800	COG0693	protein deglycase activity
G4O42_RS14805	COG0840	transmembrane signaling receptor activity
G4O42_RS14810	COG0840	transmembrane signaling receptor activity
G4O42_RS14815	COG0840	transmembrane signaling receptor activity
G4O42_RS14820	COG0840	transmembrane signaling receptor activity
G4O42_RS14835	COG2070	2-Nitropropane dioxygenase
G4O42_RS14840	COG0432	Pfam Uncharacterised protein family UPF0047
G4O42_RS14845	COG0366	Alpha amylase catalytic
G4O42_RS14850	COG1253	flavin adenine dinucleotide binding
G4O42_RS14855	COG2738	Putative neutral zinc metallopeptidase
G4O42_RS14870	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G4O42_RS14895	COG1335	isochorismatase
G4O42_RS14900	COG1979	alcohol dehydrogenase
G4O42_RS14905	COG1979	alcohol dehydrogenase
G4O42_RS14910	COG2155	Conserved Protein
G4O42_RS14915	COG1098	S1 RNA binding domain
G4O42_RS14920	COG0436	Aminotransferase
G4O42_RS14925	COG1522	sequence-specific DNA binding
G4O42_RS14930	COG2267	carboxylic ester hydrolase activity
G4O42_RS14940	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
G4O42_RS14945	COG2205	protein histidine kinase activity
G4O42_RS14955	COG5018	Exonuclease
G4O42_RS14960	COG2814	Major facilitator Superfamily
G4O42_RS14965	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G4O42_RS14970	COG3011	Protein conserved in bacteria
G4O42_RS14980	COG3290	protein histidine kinase activity
G4O42_RS14985	COG4565	transcriptional regulatory protein
G4O42_RS15015	COG2111	Na H antiporter
G4O42_RS15015	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G4O42_RS15020	COG2111	Na H antiporter
G4O42_RS15025	COG1006	Multisubunit Na H antiporter MnhC subunit
G4O42_RS15030	COG0651	ATP synthesis coupled electron transport
G4O42_RS15035	COG1863	multisubunit Na H antiporter MnhE subunit
G4O42_RS15040	COG2212	antiporter activity
G4O42_RS15045	COG1320	monovalent cation:proton antiporter activity
G4O42_RS15050	COG2050	protein possibly involved in aromatic compounds catabolism
G4O42_RS15055	COG2197	response regulator
G4O42_RS15060	COG4585	Histidine kinase
G4O42_RS15090	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
G4O42_RS15095	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
G4O42_RS15100	COG1335	isochorismatase
G4O42_RS15105	COG5506	Protein of unknown function (DUF1694)
G4O42_RS15120	COG0628	permease
G4O42_RS15130	COG1418	mRNA catabolic process
G4O42_RS15135	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_RS15145	COG1511	domain protein
G4O42_RS15150	COG1674	ftsk spoiiie
G4O42_RS15150	COG0433	COG0433 Predicted ATPase
G4O42_RS15155	COG4499	WXG100 protein secretion system (Wss), protein YukC
G4O42_RS15160	COG5417	Belongs to the EsaB family
G4O42_RS15165	COG4842	Belongs to the WXG100 family
G4O42_RS15170	COG2508	Transcriptional regulator
G4O42_RS15170	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
G4O42_RS15175	COG0686	Belongs to the AlaDH PNT family
G4O42_RS15180	COG5634	Uncharacterized conserved protein (DUF2278)
G4O42_RS15185	COG3251	PFAM MbtH domain protein
G4O42_RS15190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_RS15195	COG3433	isochorismatase activity
G4O42_RS15195	COG1535	isochorismatase
G4O42_RS15200	COG1021	2,3-dihydroxybenzoate-AMP ligase
G4O42_RS15205	COG1169	isochorismate synthase
G4O42_RS15210	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_RS15215	COG2819	hydrolase of the alpha beta superfamily
G4O42_RS15220	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G4O42_RS15225	COG1268	BioY protein
G4O42_RS15230	COG2056	Na+-H+ antiporter family
G4O42_RS15240	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
G4O42_RS15245	COG3584	3D domain protein
G4O42_RS15260	COG1252	NADH dehydrogenase
G4O42_RS15290	COG1131	(ABC) transporter
G4O42_RS15310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G4O42_RS15315	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
G4O42_RS15320	COG0316	Belongs to the HesB IscA family
G4O42_RS15330	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
G4O42_RS15340	COG1252	NADH dehydrogenase
G4O42_RS15345	COG4837	Protein of unknown function (DUF1462)
G4O42_RS15350	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
G4O42_RS15355	COG1506	peptidase
G4O42_RS15355	COG4946	Tricorn protease homolog
G4O42_RS15355	COG0823	Involved in the tonB-independent uptake of proteins
G4O42_RS15365	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G4O42_RS15370	COG0460	homoserine dehydrogenase
G4O42_RS15375	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G4O42_RS15380	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
G4O42_RS15385	COG0647	UMP catabolic process
G4O42_RS15390	COG2445	Protein of unknown function DUF86
G4O42_RS15395	COG4470	Protein conserved in bacteria
G4O42_RS15405	COG0739	heme binding
G4O42_RS15415	COG0737	Belongs to the 5'-nucleotidase family
G4O42_RS15420	COG0730	response to heat
G4O42_RS15425	COG1801	Protein of unknown function DUF72
G4O42_RS15440	COG2508	Transcriptional regulator
G4O42_RS15460	COG2814	Major facilitator Superfamily
G4O42_RS15465	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
G4O42_RS15470	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G4O42_RS15475	COG2356	endonuclease I
G4O42_RS15480	COG3842	ATPase activity
G4O42_RS15485	COG2188	Transcriptional regulator
G4O42_RS15490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G4O42_RS15495	COG0395	ABC-type sugar transport system, permease component
G4O42_RS15500	COG1175	transmembrane transport
G4O42_RS15505	COG1653	transport
G4O42_RS15510	COG2222	sugar isomerase
G4O42_RS15515	COG0789	Transcriptional regulator
G4O42_RS15540	COG0322	excinuclease ABC activity
G4O42_RS15545	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G4O42_RS15565	COG3409	Peptidoglycan-binding domain 1 protein
G4O42_RS15570	COG0719	Fe-S assembly protein
G4O42_RS15575	COG0822	iron-sulfur transferase activity
G4O42_RS15580	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G4O42_RS15585	COG0719	Fe-S assembly protein
G4O42_RS15590	COG0396	ATPase activity
G4O42_RS15600	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G4O42_RS15605	COG1464	Belongs to the NlpA lipoprotein family
G4O42_RS15610	COG2011	ABC-type metal ion transport system permease component
G4O42_RS15615	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
G4O42_RS15625	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G4O42_RS15630	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
G4O42_RS15645	COG1393	Belongs to the ArsC family
G4O42_RS15650	COG1960	acyl-CoA dehydrogenase activity
G4O42_RS15655	COG0183	Belongs to the thiolase family
G4O42_RS15660	COG1024	Enoyl-CoA hydratase
G4O42_RS15660	COG1250	3-hydroxyacyl-CoA dehydrogenase
G4O42_RS15680	COG5577	PFAM Coat F domain
G4O42_RS15685	COG1846	Transcriptional regulator
G4O42_RS15690	COG0477	Major facilitator Superfamily
G4O42_RS15695	COG1942	4-Oxalocrotonate Tautomerase
G4O42_RS15700	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_RS15705	COG0583	DNA-binding transcription factor activity
G4O42_RS15715	COG0583	DNA-binding transcription factor activity
G4O42_RS15735	COG1120	ATPase activity
G4O42_RS15750	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_RS15755	COG0783	Belongs to the Dps family
G4O42_RS15760	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G4O42_RS15765	COG0745	RESPONSE REGULATOR receiver
G4O42_RS15770	COG2205	protein histidine kinase activity
G4O42_RS15770	COG2770	Histidine kinase
G4O42_RS15780	COG1309	transcriptional regulator
G4O42_RS15785	COG0114	fumarate hydratase activity
G4O42_RS15795	COG0697	spore germination
G4O42_RS15800	COG0814	amino acid
G4O42_RS15810	COG2197	response regulator
G4O42_RS15815	COG4585	Histidine kinase
G4O42_RS15820	COG4758	membrane
G4O42_RS15825	COG3595	metallopeptidase activity
G4O42_RS15830	COG1842	Phage shock protein A
G4O42_RS15835	COG4758	membrane
G4O42_RS15840	COG2814	Major facilitator Superfamily
G4O42_RS15845	COG2096	Adenosyltransferase
G4O42_RS15850	COG1120	ATPase activity
G4O42_RS15855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G4O42_RS15860	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G4O42_RS15865	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_RS15870	COG3386	PFAM SMP-30 Gluconolaconase
G4O42_RS15875	COG2205	protein histidine kinase activity
G4O42_RS15880	COG0745	RESPONSE REGULATOR receiver
G4O42_RS15890	COG1191	sigma factor activity
G4O42_RS15900	COG2140	Oxalate decarboxylase
G4O42_RS15910	COG1120	ATPase activity
G4O42_RS15915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G4O42_RS15920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G4O42_RS15925	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G4O42_RS15930	COG0531	amino acid
G4O42_RS15940	COG1988	membrane-bound metal-dependent
G4O42_RS15945	COG1368	sulfuric ester hydrolase activity
G4O42_RS15950	COG1910	domain protein
G4O42_RS15955	COG0725	ABC transporter, periplasmic molybdate-binding protein
G4O42_RS15960	COG4149	molybdate abc transporter
G4O42_RS15965	COG2197	response regulator
G4O42_RS15970	COG3850	Histidine kinase
G4O42_RS15975	COG1131	(ABC) transporter
G4O42_RS15985	COG0842	Transport permease protein
G4O42_RS15990	COG0656	L-ascorbic acid biosynthetic process
G4O42_RS16010	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G4O42_RS16015	COG3973	AAA domain
G4O42_RS16020	COG2860	membrane
G4O42_RS16030	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
G4O42_RS16035	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G4O42_RS16040	COG2217	Heavy metal translocating P-type atpase
G4O42_RS16045	COG2217	Heavy metal translocating P-type atpase
G4O42_RS16050	COG2608	mercury ion transmembrane transporter activity
G4O42_RS16055	COG1937	Protein conserved in bacteria
G4O42_RS16060	COG0673	inositol 2-dehydrogenase activity
G4O42_RS16070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G4O42_RS16075	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
G4O42_RS16080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G4O42_RS16085	COG1126	abc transporter atp-binding protein
G4O42_RS16090	COG0765	amino acid transport
G4O42_RS16095	COG0765	amino acid transport
G4O42_RS16100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G4O42_RS16105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G4O42_RS16110	COG0454	-acetyltransferase
G4O42_RS16115	COG0583	DNA-binding transcription factor activity
G4O42_RS16120	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_RS16165	COG0557	exoribonuclease II activity
G4O42_RS16170	COG1647	Serine aminopeptidase, S33
G4O42_RS16175	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G4O42_RS16180	COG1476	TRANSCRIPTIONal
G4O42_RS16185	COG1396	sequence-specific DNA binding
G4O42_RS16190	COG1396	sequence-specific DNA binding
G4O42_RS16195	COG1733	regulation of RNA biosynthetic process
G4O42_RS16220	COG1131	(ABC) transporter
G4O42_RS16225	COG1174	glycine betaine transport
G4O42_RS16230	COG1732	Glycine betaine
G4O42_RS16235	COG1174	glycine betaine transport
G4O42_RS16240	COG1125	glycine betaine transport
G4O42_RS16240	COG0517	IMP dehydrogenase activity
G4O42_RS16245	COG1510	regulation of RNA biosynthetic process
G4O42_RS16250	COG1174	glycine betaine transport
G4O42_RS16255	COG1732	Glycine betaine
G4O42_RS16260	COG1174	glycine betaine transport
G4O42_RS16265	COG1125	glycine betaine transport
G4O42_RS16265	COG0517	IMP dehydrogenase activity
G4O42_RS16270	COG1510	regulation of RNA biosynthetic process
G4O42_RS16275	COG2095	MarC family integral membrane protein
G4O42_RS16280	COG3064	Membrane
G4O42_RS16285	COG4640	response to antibiotic
G4O42_RS16290	COG0456	acetyltransferase
G4O42_RS16305	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G4O42_RS16325	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G4O42_RS16330	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G4O42_RS16340	COG2234	aminopeptidase activity
G4O42_RS16360	COG0126	phosphoglycerate kinase activity
G4O42_RS16365	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G4O42_RS16370	COG2390	Transcriptional regulator
G4O42_RS16375	COG2814	Major facilitator Superfamily
G4O42_RS16380	COG1609	Transcriptional regulator
G4O42_RS16385	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G4O42_RS16395	COG0583	DNA-binding transcription factor activity
G4O42_RS16400	COG0697	spore germination
G4O42_RS16405	COG1113	amino acid transport
G4O42_RS16410	COG1609	Transcriptional regulator
G4O42_RS16420	COG0561	phosphatase activity
G4O42_RS16425	COG1737	Transcriptional regulator
G4O42_RS16430	COG1070	Carbohydrate kinase
G4O42_RS16470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G4O42_RS16475	COG2186	Transcriptional regulator
G4O42_RS16480	COG1620	l-lactate permease
G4O42_RS16485	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
G4O42_RS16495	COG5039	Polysaccharide pyruvyl transferase
G4O42_RS16500	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G4O42_RS16505	COG0110	maltose O-acetyltransferase activity
G4O42_RS16510	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G4O42_RS16515	COG2244	polysaccharide biosynthetic process
G4O42_RS16520	COG1216	Glycosyl transferase, family 2
G4O42_RS16525	COG5039	Polysaccharide pyruvyl transferase
G4O42_RS16530	COG1216	Glycosyl transferase, family 2
G4O42_RS16540	COG0438	transferase activity, transferring glycosyl groups
G4O42_RS16545	COG1215	transferase activity, transferring glycosyl groups
G4O42_RS16550	COG0438	transferase activity, transferring glycosyl groups
G4O42_RS16555	COG1086	Polysaccharide biosynthesis protein
G4O42_RS16560	COG0489	protein tyrosine kinase activity
G4O42_RS16565	COG3944	biosynthesis protein
G4O42_RS16570	COG1396	sequence-specific DNA binding
G4O42_RS16575	COG2272	Belongs to the type-B carboxylesterase lipase family
G4O42_RS16580	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
G4O42_RS16585	COG2364	Membrane
G4O42_RS16590	COG0456	acetyltransferase
G4O42_RS16595	COG3479	Phenolic acid decarboxylase
G4O42_RS16645	COG2223	nitrite transmembrane transporter activity
G4O42_RS16650	COG1609	Transcriptional regulator
G4O42_RS16660	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G4O42_RS16665	COG0366	Alpha amylase catalytic
G4O42_RS16670	COG1554	hydrolase, family 65, central catalytic
G4O42_RS16675	COG5521	maltodextrose utilization protein MalA
G4O42_RS16680	COG3833	ABC-type maltose transport systems, permease component
G4O42_RS16685	COG1175	transmembrane transport
G4O42_RS16690	COG2182	Extracellular solute-binding protein
G4O42_RS16695	COG0366	Alpha amylase catalytic
G4O42_RS16700	COG1609	Transcriptional regulator
G4O42_RS16705	COG1611	Belongs to the LOG family
G4O42_RS16710	COG1694	Mazg nucleotide pyrophosphohydrolase
G4O42_RS16715	COG0659	secondary active sulfate transmembrane transporter activity
G4O42_RS16720	COG0288	reversible hydration of carbon dioxide
G4O42_RS16730	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G4O42_RS16735	COG4290	ribonuclease
G4O42_RS16740	COG2162	N-hydroxyarylamine O-acetyltransferase activity
G4O42_RS16745	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G4O42_RS16755	COG0391	Required for morphogenesis under gluconeogenic growth conditions
G4O42_RS16765	COG1051	belongs to the nudix hydrolase family
G4O42_RS16770	COG0492	ferredoxin-NADP+ reductase activity
G4O42_RS16775	COG0791	NLP P60 protein
G4O42_RS16775	COG3883	PFAM NLP P60 protein
G4O42_RS16780	COG0457	Tetratricopeptide repeat
G4O42_RS16785	COG5002	protein histidine kinase activity
G4O42_RS16790	COG0745	RESPONSE REGULATOR receiver
G4O42_RS16795	COG1132	(ABC) transporter
G4O42_RS16800	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
G4O42_RS16800	COG0140	phosphoribosyl-ATP diphosphatase activity
G4O42_RS16825	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
G4O42_RS16840	COG4990	cell redox homeostasis
G4O42_RS16845	COG0110	maltose O-acetyltransferase activity
G4O42_RS16865	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
G4O42_RS16875	COG2188	Transcriptional regulator
G4O42_RS16880	COG1309	transcriptional regulator
G4O42_RS16885	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
G4O42_RS16890	COG1950	PFAM Membrane protein of
G4O42_RS16895	COG1983	PspC domain protein
G4O42_RS16900	COG3595	metallopeptidase activity
G4O42_RS16915	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G4O42_RS16925	COG4897	Protein conserved in bacteria
G4O42_RS16930	COG3848	Pyruvate phosphate dikinase
G4O42_RS16930	COG0574	Belongs to the PEP-utilizing enzyme family
G4O42_RS16935	COG1309	transcriptional regulator
G4O42_RS16940	COG2814	Major facilitator Superfamily
G4O42_RS16955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G4O42_RS16965	COG3409	Peptidoglycan-binding domain 1 protein
G4O42_RS16965	COG0793	Belongs to the peptidase S41A family
G4O42_RS16970	COG3420	alginic acid biosynthetic process
G4O42_RS16975	COG2177	Part of the ABC transporter FtsEX involved in
G4O42_RS16980	COG2884	Cell division ATP-binding protein ftsE
G4O42_RS16985	COG2010	Cytochrome c
G4O42_RS16990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G4O42_RS17005	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
G4O42_RS17020	COG1516	flagellar protein fliS
G4O42_RS17025	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
G4O42_RS17030	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
G4O42_RS17050	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
G4O42_RS17055	COG4786	Flagellar basal body rod
G4O42_RS17055	COG1256	bacterial-type flagellum assembly
G4O42_RS17060	COG3418	PFAM FlgN family protein
G4O42_RS17065	COG2747	anti-sigma28 factor FlgM
G4O42_RS17075	COG1040	competence protein
G4O42_RS17085	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
G4O42_RS17090	COG1307	EDD domain protein, DegV family
G4O42_RS17095	COG2197	response regulator
G4O42_RS17100	COG4585	Histidine kinase
G4O42_RS17105	COG1739	Uncharacterized protein family UPF0029
G4O42_RS17110	COG1316	TRANSCRIPTIONal
G4O42_RS17115	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G4O42_RS17120	COG0438	transferase activity, transferring glycosyl groups
G4O42_RS17125	COG1215	transferase activity, transferring glycosyl groups
G4O42_RS17130	COG3206	protein involved in exopolysaccharide biosynthesis
G4O42_RS17135	COG3307	-O-antigen
G4O42_RS17140	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
G4O42_RS17145	COG0297	glycogen (starch) synthase activity
G4O42_RS17145	COG0438	transferase activity, transferring glycosyl groups
G4O42_RS17150	COG2244	polysaccharide biosynthetic process
G4O42_RS17160	COG2247	cell wall binding repeat
G4O42_RS17160	COG0860	N-Acetylmuramoyl-L-alanine amidase
G4O42_RS17165	COG2385	sporulation resulting in formation of a cellular spore
G4O42_RS17165	COG2247	cell wall binding repeat
G4O42_RS17175	COG1316	TRANSCRIPTIONal
G4O42_RS17180	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
G4O42_RS17185	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G4O42_RS17190	COG1134	teichoic acid transport
G4O42_RS17195	COG1682	transport, permease protein
G4O42_RS17200	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
G4O42_RS17210	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
G4O42_RS17215	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
G4O42_RS17220	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
G4O42_RS17225	COG4193	domain, Protein
G4O42_RS17230	COG1482	cell wall glycoprotein biosynthetic process
G4O42_RS17235	COG0697	spore germination
G4O42_RS17240	COG0814	amino acid
G4O42_RS17250	COG1215	transferase activity, transferring glycosyl groups
G4O42_RS17255	COG2814	Major facilitator Superfamily
G4O42_RS17260	COG1316	TRANSCRIPTIONal
G4O42_RS17265	COG0561	phosphatase activity
G4O42_RS17270	COG2433	Pfam Transposase IS66
G4O42_RS17275	COG0791	NLP P60 protein
G4O42_RS17285	COG2843	Capsule synthesis protein
G4O42_RS17295	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
G4O42_RS17300	COG0697	spore germination
G4O42_RS17305	COG0814	amino acid
G4O42_RS17315	COG1609	Transcriptional regulator
G4O42_RS17320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G4O42_RS17330	COG1129	ABC transporter
G4O42_RS17335	COG1172	Belongs to the binding-protein-dependent transport system permease family
G4O42_RS17340	COG1879	ABC-type sugar transport system periplasmic component
G4O42_RS17345	COG3103	Sh3 type 3 domain protein
G4O42_RS17350	COG2249	NAD(P)H dehydrogenase (quinone) activity
G4O42_RS17355	COG3527	Alpha-acetolactate decarboxylase
G4O42_RS17360	COG0028	Belongs to the TPP enzyme family
G4O42_RS17365	COG0583	DNA-binding transcription factor activity
G4O42_RS17370	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
G4O42_RS17385	COG5337	Spore coat protein CotH
G4O42_RS17395	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G4O42_RS17405	COG0405	Gamma-glutamyltransferase
G4O42_RS17410	COG1522	sequence-specific DNA binding
G4O42_RS17415	COG2059	Chromate
G4O42_RS17420	COG2059	Chromate
G4O42_RS17430	COG0655	NAD(P)H dehydrogenase (quinone) activity
G4O42_RS17435	COG0583	DNA-binding transcription factor activity
G4O42_RS17465	COG5444	nuclease activity
G4O42_RS17480	COG3878	Protein conserved in bacteria
G4O42_RS17485	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
G4O42_RS17490	COG4464	protein tyrosine phosphatase activity
G4O42_RS17495	COG0489	protein tyrosine kinase activity
G4O42_RS17500	COG3944	biosynthesis protein
G4O42_RS17510	COG4715	Zinc finger, swim domain protein
G4O42_RS17515	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G4O42_RS17520	COG0561	phosphatase activity
G4O42_RS17525	COG1349	DNA-binding transcription factor activity
G4O42_RS17530	COG0629	single-stranded DNA binding
G4O42_RS17555	COG0457	Tetratricopeptide repeat
G4O42_RS17560	COG4786	Flagellar basal body rod
G4O42_RS17565	COG4786	Flagellar basal body rod
G4O42_RS17570	COG1077	Cell shape determining protein MreB Mrl
G4O42_RS17575	COG1609	Transcriptional regulator
G4O42_RS17580	COG1846	Transcriptional regulator
G4O42_RS17585	COG2814	Major facilitator Superfamily
G4O42_RS17590	COG1953	Uracil, thiamine, allantoin
G4O42_RS17595	COG0477	Major facilitator Superfamily
G4O42_RS17600	COG1335	isochorismatase
G4O42_RS17605	COG0004	ammonium transporteR
G4O42_RS17610	COG0347	Belongs to the P(II) protein family
G4O42_RS17615	COG0772	Belongs to the SEDS family
G4O42_RS17620	COG0671	phosphoesterase, PA-phosphatase related
G4O42_RS17630	COG0739	heme binding
G4O42_RS17635	COG1247	-acetyltransferase
G4O42_RS17650	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G4O42_RS17660	COG0726	polysaccharide deacetylase
G4O42_RS17670	COG1959	2 iron, 2 sulfur cluster binding
G4O42_RS17685	COG0831	urea catabolic process
G4O42_RS17690	COG3237	CsbD-like
G4O42_RS17695	COG1994	Peptidase M50
G4O42_RS17700	COG0457	Tetratricopeptide repeat
G4O42_RS17710	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
G4O42_RS17720	COG2304	oxidoreductase activity
G4O42_RS17725	COG2304	oxidoreductase activity
G4O42_RS17730	COG2385	sporulation resulting in formation of a cellular spore
G4O42_RS17735	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G4O42_RS17745	COG4836	Membrane
G4O42_RS17815	COG0698	ribose 5-phosphate isomerase
G4O42_RS17820	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G4O42_RS17830	COG0009	L-threonylcarbamoyladenylate synthase
G4O42_RS17835	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
G4O42_RS17855	COG2890	protein-(glutamine-N5) methyltransferase activity
G4O42_RS17860	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
G4O42_RS17865	COG0346	lactoylglutathione lyase activity
G4O42_RS17870	COG0789	Transcriptional regulator
G4O42_RS17875	COG0679	Auxin Efflux Carrier
G4O42_RS17880	COG0281	malic enzyme
G4O42_RS17895	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
G4O42_RS17900	COG1494	fructose-1,6-bisphosphatase
G4O42_RS17905	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G4O42_RS17915	COG0191	fructose-bisphosphate aldolase activity
G4O42_RS17920	COG2204	response regulator
G4O42_RS17925	COG4821	SIS domain
G4O42_RS17940	COG2181	nitrate reductase activity
G4O42_RS17940	COG0247	lactate metabolic process
G4O42_RS17945	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G4O42_RS17960	COG1132	(ABC) transporter
G4O42_RS17965	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G4O42_RS17975	COG2181	nitrate reductase activity
G4O42_RS17980	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
G4O42_RS17985	COG1140	nitrate reductase beta subunit
G4O42_RS17990	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
G4O42_RS17995	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G4O42_RS18005	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G4O42_RS18010	COG2223	nitrite transmembrane transporter activity
G4O42_RS18020	COG4506	Protein conserved in bacteria
G4O42_RS18030	COG3391	amine dehydrogenase activity
G4O42_RS18035	COG3391	amine dehydrogenase activity
G4O42_RS18040	COG0457	Tetratricopeptide repeat
G4O42_RS18050	COG0010	Belongs to the arginase family
G4O42_RS18055	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
G4O42_RS18060	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G4O42_RS18075	COG1994	Peptidase M50
G4O42_RS18080	COG1942	4-Oxalocrotonate Tautomerase
G4O42_RS18085	COG1846	Transcriptional regulator
G4O42_RS18090	COG0531	amino acid
G4O42_RS18095	COG3465	dGTPase activity
G4O42_RS18100	COG1078	dGTPase activity
G4O42_RS18115	COG1695	Transcriptional regulator
G4O42_RS18125	COG1131	(ABC) transporter
G4O42_RS18130	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
G4O42_RS18160	COG0583	DNA-binding transcription factor activity
G4O42_RS18165	COG2855	membrane
G4O42_RS18170	COG0280	phosphate acetyltransferase
G4O42_RS18180	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_RS18185	COG0436	Aminotransferase
G4O42_RS18215	COG2814	Major facilitator Superfamily
G4O42_RS18220	COG2814	Major facilitator Superfamily
G4O42_RS18225	COG0833	amino acid
G4O42_RS18230	COG4187	Peptidase family M20/M25/M40
G4O42_RS18235	COG1012	belongs to the aldehyde dehydrogenase family
G4O42_RS18240	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G4O42_RS18245	COG2205	protein histidine kinase activity
G4O42_RS18250	COG0745	RESPONSE REGULATOR receiver
G4O42_RS18265	COG1131	(ABC) transporter
G4O42_RS18270	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
G4O42_RS18275	COG1091	dTDP-4-dehydrorhamnose reductase activity
G4O42_RS18280	COG1088	dTDP-glucose 4,6-dehydratase activity
G4O42_RS18285	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
G4O42_RS18290	COG3980	spore coat polysaccharide biosynthesis protein
G4O42_RS18295	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
G4O42_RS18300	COG2089	acid synthase
G4O42_RS18305	COG0456	acetyltransferase
G4O42_RS18310	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G4O42_RS18315	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
G4O42_RS18320	COG0463	Glycosyl transferase, family 2
G4O42_RS18330	COG2363	Small membrane protein
G4O42_RS18335	COG2233	PERMEase
G4O42_RS18350	COG1216	Glycosyl transferase, family 2
G4O42_RS18365	COG1695	Transcriptional regulator
G4O42_RS18370	COG0351	phosphomethylpyrimidine kinase
G4O42_RS18380	COG1621	beta-fructofuranosidase activity
G4O42_RS18385	COG1263	PTS System
G4O42_RS18385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G4O42_RS18390	COG3711	transcriptional antiterminator
G4O42_RS18400	COG1404	Belongs to the peptidase S8 family
G4O42_RS18405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G4O42_RS18410	COG0778	Nitroreductase
G4O42_RS18415	COG0772	Belongs to the SEDS family
G4O42_RS18420	COG0454	-acetyltransferase
G4O42_RS18440	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G4O42_RS18445	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G4O42_RS18450	COG2261	transglycosylase associated protein
G4O42_RS18455	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
G4O42_RS18460	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
G4O42_RS18465	COG2246	polysaccharide biosynthetic process
G4O42_RS18470	COG1309	transcriptional regulator
G4O42_RS18490	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
G4O42_RS18495	COG2837	iron assimilation
G4O42_RS18510	COG0583	DNA-binding transcription factor activity
G4O42_RS18520	COG1346	cytolysis
G4O42_RS18525	COG4895	conserved protein (DUF2196)
G4O42_RS18530	COG0789	Transcriptional regulator
G4O42_RS18535	COG5504	Zn-dependent protease
G4O42_RS18540	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
G4O42_RS18545	COG0346	lactoylglutathione lyase activity
G4O42_RS18550	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G4O42_RS18555	COG1404	Belongs to the peptidase S8 family
G4O42_RS18560	COG1442	glycosyl transferase family 8
G4O42_RS18565	COG2357	RelA SpoT domain protein
G4O42_RS18570	COG1575	Belongs to the MenA family. Type 1 subfamily
G4O42_RS18585	COG1696	Membrane protein involved in D-alanine export
G4O42_RS18595	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
G4O42_RS18600	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G4O42_RS18605	COG1486	melibiose metabolic process
G4O42_RS18610	COG1447	Phosphotransferase system cellobiose-specific component IIA
G4O42_RS18615	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G4O42_RS18620	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G4O42_RS18625	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G4O42_RS18625	COG3711	transcriptional antiterminator
G4O42_RS18635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G4O42_RS18640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G4O42_RS18650	COG0640	Transcriptional regulator
G4O42_RS18655	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
G4O42_RS18660	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G4O42_RS18665	COG1447	Phosphotransferase system cellobiose-specific component IIA
G4O42_RS18670	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G4O42_RS18675	COG2723	6-phospho-beta-galactosidase activity
G4O42_RS18685	COG1482	cell wall glycoprotein biosynthetic process
G4O42_RS18695	COG0753	catalase activity
G4O42_RS18700	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
G4O42_RS18705	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
G4O42_RS18725	COG3279	Response regulator of the LytR AlgR family
G4O42_RS18745	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
G4O42_RS18750	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
G4O42_RS18755	COG4988	ABC transporter
G4O42_RS18760	COG1294	oxidase, subunit
G4O42_RS18765	COG1271	oxidase subunit
G4O42_RS18770	COG3493	citrate carrier protein
G4O42_RS18775	COG0726	polysaccharide deacetylase
G4O42_RS18780	COG3842	ATPase activity
G4O42_RS18785	COG2508	Transcriptional regulator
G4O42_RS18790	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G4O42_RS18800	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G4O42_RS18815	COG4894	glucomannan catabolic process
G4O42_RS18820	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
G4O42_RS18825	COG0500	methyltransferase
G4O42_RS18830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
G4O42_RS18845	COG0693	protein deglycase activity
G4O42_RS18845	COG0753	catalase activity
G4O42_RS18850	COG2851	Citrate transporter
G4O42_RS18855	COG2273	Hydrolase Family 16
G4O42_RS18865	COG2270	Major facilitator Superfamily
G4O42_RS18870	COG0513	Belongs to the DEAD box helicase family
G4O42_RS18880	COG0697	spore germination
G4O42_RS18885	COG0589	response to stress
G4O42_RS18945	COG3507	Belongs to the glycosyl hydrolase 43 family
G4O42_RS18970	COG0010	Belongs to the arginase family
G4O42_RS18975	COG0833	amino acid
G4O42_RS18980	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
G4O42_RS18985	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
G4O42_RS18995	COG2390	Transcriptional regulator
G4O42_RS19000	COG0561	phosphatase activity
G4O42_RS19030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G4O42_RS19035	COG5294	Protein conserved in bacteria
G4O42_RS19040	COG0577	efflux transmembrane transporter activity
G4O42_RS19045	COG1136	(ABC) transporter
G4O42_RS19050	COG2205	protein histidine kinase activity
G4O42_RS19055	COG0745	RESPONSE REGULATOR receiver
G4O42_RS19060	COG2205	protein histidine kinase activity
G4O42_RS19065	COG0745	RESPONSE REGULATOR receiver
G4O42_RS19095	COG1082	Xylose isomerase domain protein TIM barrel
G4O42_RS19105	COG2814	Major facilitator Superfamily
G4O42_RS19135	COG1349	DNA-binding transcription factor activity
G4O42_RS19140	COG0667	Aldo Keto reductase
G4O42_RS19145	COG2814	Major facilitator Superfamily
G4O42_RS19160	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_RS19165	COG2197	response regulator
G4O42_RS19170	COG4585	Histidine kinase
G4O42_RS19175	COG3239	Fatty acid desaturase
G4O42_RS19180	COG1309	transcriptional regulator
G4O42_RS19185	COG1012	belongs to the aldehyde dehydrogenase family
G4O42_RS19190	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G4O42_RS19200	COG0640	Transcriptional regulator
G4O42_RS19205	COG2814	Major facilitator Superfamily
G4O42_RS19210	COG1714	RDD family
G4O42_RS19220	COG0450	alkyl hydroperoxide reductase
G4O42_RS19225	COG3634	alkyl hydroperoxide reductase activity
G4O42_RS19230	COG3177	Filamentation induced by cAMP protein fic
G4O42_RS19235	COG1113	amino acid transport
G4O42_RS19245	COG2080	2 iron, 2 sulfur cluster binding
G4O42_RS19260	COG2068	MobA-Related Protein
G4O42_RS19265	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
G4O42_RS19320	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
G4O42_RS19325	COG0667	Aldo Keto reductase
G4O42_RS19330	COG0456	acetyltransferase
G4O42_RS19335	COG0457	Tetratricopeptide repeat
G4O42_RS19340	COG0010	Belongs to the arginase family
G4O42_RS19345	COG0833	amino acid
G4O42_RS19350	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G4O42_RS19355	COG5658	integral membrane protein
G4O42_RS19360	COG0640	Transcriptional regulator
G4O42_RS19365	COG3829	transcription factor binding
G4O42_RS19375	COG0488	(ABC) transporter
G4O42_RS19390	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
G4O42_RS19395	COG3850	Histidine kinase
G4O42_RS19395	COG5002	protein histidine kinase activity
G4O42_RS19400	COG0745	RESPONSE REGULATOR receiver
G4O42_RS19405	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G4O42_RS19410	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
G4O42_RS19415	COG4853	Protein conserved in bacteria
G4O42_RS19420	COG4863	YycH protein
G4O42_RS19425	COG5002	protein histidine kinase activity
G4O42_RS19430	COG0745	RESPONSE REGULATOR receiver
G4O42_RS19460	COG0346	lactoylglutathione lyase activity
G4O42_RS19465	COG0305	Participates in initiation and elongation during chromosome replication
G4O42_RS19480	COG3093	addiction module antidote protein HigA
G4O42_RS19485	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G4O42_RS19490	COG0297	glycogen (starch) synthase activity
G4O42_RS19500	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
G4O42_RS19505	COG0438	transferase activity, transferring glycosyl groups
G4O42_RS19525	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
G4O42_RS19530	COG4241	membrane
G4O42_RS19540	COG5577	PFAM Coat F domain
G4O42_RS19545	COG1733	regulation of RNA biosynthetic process
G4O42_RS19555	COG0697	spore germination
G4O42_RS19560	COG1621	beta-fructofuranosidase activity
G4O42_RS19565	COG1621	beta-fructofuranosidase activity
G4O42_RS19575	COG2318	DinB family
G4O42_RS19580	COG2211	Major facilitator Superfamily
G4O42_RS19590	COG0778	Nitroreductase
G4O42_RS19595	COG1846	Transcriptional regulator
G4O42_RS19600	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G4O42_RS19605	COG1846	Transcriptional regulator
G4O42_RS19610	COG2153	protein acetylation
G4O42_RS19620	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G4O42_RS19625	COG0583	DNA-binding transcription factor activity
G4O42_RS19630	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_RS19635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G4O42_RS19640	COG0697	spore germination
G4O42_RS19645	COG1331	Highly conserved protein containing a thioredoxin domain
G4O42_RS19670	COG1331	Highly conserved protein containing a thioredoxin domain
G4O42_RS19675	COG1266	CAAX protease self-immunity
G4O42_RS19680	COG2814	Major facilitator Superfamily
G4O42_RS19680	COG0477	Major facilitator Superfamily
G4O42_RS19685	COG0346	lactoylglutathione lyase activity
G4O42_RS19690	COG1609	Transcriptional regulator
G4O42_RS19695	COG0708	Exodeoxyribonuclease III
G4O42_RS19700	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G4O42_RS19705	COG2169	Transcriptional regulator
G4O42_RS19715	COG0629	single-stranded DNA binding
G4O42_RS19725	COG0012	GTP binding
G4O42_RS19730	COG0243	molybdopterin cofactor binding
G4O42_RS19735	COG4481	Protein conserved in bacteria
G4O42_RS19740	COG3949	Membrane
G4O42_RS19755	COG1475	DNA binding
G4O42_RS19760	COG1192	Involved in chromosome partitioning
G4O42_RS19785	COG1847	R3H domain protein
G4O42_RS19790	COG0706	membrane insertase activity