locus-tag	class	description
KPL75_RS00045	COG2124	cytochrome p450
KPL75_RS00085	COG0463	Glycosyl transferase, family 2
KPL75_RS00100	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KPL75_RS00110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KPL75_RS00135	COG0577	efflux transmembrane transporter activity
KPL75_RS00140	COG1136	(ABC) transporter
KPL75_RS00155	COG0488	(ABC) transporter
KPL75_RS00160	COG0667	Aldo Keto reductase
KPL75_RS00165	COG0583	DNA-binding transcription factor activity
KPL75_RS00180	COG2205	protein histidine kinase activity
KPL75_RS00185	COG0745	RESPONSE REGULATOR receiver
KPL75_RS00195	COG3773	Cell wall hydrolase
KPL75_RS00200	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
KPL75_RS00210	COG3386	PFAM SMP-30 Gluconolaconase
KPL75_RS00250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KPL75_RS00265	COG2959	enzyme of heme biosynthesis
KPL75_RS00300	COG3844	kynureninase activity
KPL75_RS00305	COG1309	transcriptional regulator
KPL75_RS00330	COG3284	Transcriptional regulator
KPL75_RS00345	COG1349	DNA-binding transcription factor activity
KPL75_RS00365	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KPL75_RS00370	COG0508	dehydrogenase complex catalyzes the overall conversion of
KPL75_RS00375	COG0022	dehydrogenase e1 component
KPL75_RS00380	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KPL75_RS00400	COG1028	Short-chain dehydrogenase reductase Sdr
KPL75_RS00440	COG4176	ABC-type proline glycine betaine transport system permease component
KPL75_RS00445	COG4175	Glycine betaine
KPL75_RS00445	COG0517	IMP dehydrogenase activity
KPL75_RS00470	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KPL75_RS00475	COG2153	protein acetylation
KPL75_RS00480	COG3397	chitin binding
KPL75_RS00490	COG1819	glycosyl
KPL75_RS00510	COG2205	protein histidine kinase activity
KPL75_RS00515	COG2226	methyltransferase
KPL75_RS00520	COG2315	Protein conserved in bacteria
KPL75_RS00565	COG3973	AAA domain
KPL75_RS00580	COG0514	ATP-dependent DNA helicase (RecQ)
KPL75_RS00615	COG4637	Psort location Cytoplasmic, score
KPL75_RS00635	COG1227	inorganic diphosphatase activity
KPL75_RS00640	COG3397	chitin binding
KPL75_RS00645	COG2318	DinB family
KPL75_RS00660	COG1162	GTPase activity
KPL75_RS00665	COG1115	amino acid carrier protein
KPL75_RS00670	COG1012	belongs to the aldehyde dehydrogenase family
KPL75_RS00675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KPL75_RS00685	COG3938	Belongs to the proline racemase family
KPL75_RS00690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KPL75_RS00745	COG1078	dGTPase activity
KPL75_RS00750	COG0586	Pfam SNARE associated Golgi protein
KPL75_RS00765	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KPL75_RS00770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KPL75_RS00775	COG4166	transmembrane transport
KPL75_RS00785	COG4948	Mandelate Racemase Muconate Lactonizing
KPL75_RS00800	COG0667	Aldo Keto reductase
KPL75_RS00830	COG2936	dipeptidyl-peptidase activity
KPL75_RS00840	COG0745	RESPONSE REGULATOR receiver
KPL75_RS00855	COG0456	acetyltransferase
KPL75_RS00870	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KPL75_RS00880	COG1164	Oligoendopeptidase f
KPL75_RS00885	COG0456	acetyltransferase
KPL75_RS00890	COG1307	EDD domain protein, DegV family
KPL75_RS00920	COG1181	Belongs to the D-alanine--D-alanine ligase family
KPL75_RS00935	COG2814	Major facilitator Superfamily
KPL75_RS00945	COG1664	Polymer-forming cytoskeletal
KPL75_RS00950	COG0789	Transcriptional regulator
KPL75_RS00955	COG4533	DNA binding
KPL75_RS00960	COG2814	Major facilitator Superfamily
KPL75_RS00960	COG0477	Major facilitator Superfamily
KPL75_RS00980	COG2261	transglycosylase associated protein
KPL75_RS00995	COG2226	methyltransferase
KPL75_RS01030	COG0436	Aminotransferase
KPL75_RS01035	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KPL75_RS01060	COG1131	(ABC) transporter
KPL75_RS01115	COG0628	permease
KPL75_RS01130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KPL75_RS01135	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KPL75_RS01140	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KPL75_RS01180	COG2746	aminoglycoside 3-N-acetyltransferase activity
KPL75_RS01205	COG0697	spore germination
KPL75_RS01225	COG4912	Dna alkylation repair
KPL75_RS01265	COG2814	Major facilitator Superfamily
KPL75_RS01270	COG1368	sulfuric ester hydrolase activity
KPL75_RS01280	COG0488	(ABC) transporter
KPL75_RS01285	COG2409	Drug exporters of the RND superfamily
KPL75_RS01285	COG1033	growth of symbiont in host cell
KPL75_RS01290	COG1309	transcriptional regulator
KPL75_RS01305	COG0287	Prephenate dehydrogenase
KPL75_RS01320	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KPL75_RS01320	COG1605	Chorismate mutase
KPL75_RS01350	COG3584	3D domain protein
KPL75_RS01350	COG1388	LysM domain
KPL75_RS01390	COG1309	transcriptional regulator
KPL75_RS01400	COG1595	DNA-templated transcription, initiation
KPL75_RS01425	COG0579	oxidoreductase
KPL75_RS01430	COG1879	ABC-type sugar transport system periplasmic component
KPL75_RS01435	COG1172	Belongs to the binding-protein-dependent transport system permease family
KPL75_RS01450	COG2390	Transcriptional regulator
KPL75_RS01465	COG1830	Aldolase
KPL75_RS01470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KPL75_RS01495	COG0346	lactoylglutathione lyase activity
KPL75_RS01500	COG2329	Antibiotic biosynthesis monooxygenase
KPL75_RS01520	COG1472	Belongs to the glycosyl hydrolase 3 family
KPL75_RS01525	COG2207	Transcriptional regulator
KPL75_RS01530	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KPL75_RS01535	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KPL75_RS01540	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KPL75_RS01545	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KPL75_RS01550	COG3239	Fatty acid desaturase
KPL75_RS01565	COG3655	Transcriptional regulator
KPL75_RS01580	COG4377	Putative membrane peptidase family (DUF2324)
KPL75_RS01590	COG3279	Response regulator of the LytR AlgR family
KPL75_RS01610	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KPL75_RS01615	COG0346	lactoylglutathione lyase activity
KPL75_RS01645	COG0714	Associated with various cellular activities
KPL75_RS01665	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KPL75_RS01670	COG0753	catalase activity
KPL75_RS01705	COG0778	Nitroreductase
KPL75_RS01710	COG1846	Transcriptional regulator
KPL75_RS01725	COG0494	nUDIX hydrolase
KPL75_RS01730	COG4884	unkown
KPL75_RS01730	COG3831	ATPase activity
KPL75_RS01735	COG1136	(ABC) transporter
KPL75_RS01770	COG1028	Short-chain dehydrogenase reductase Sdr
KPL75_RS01775	COG1309	transcriptional regulator
KPL75_RS01815	COG0456	acetyltransferase
KPL75_RS01830	COG0697	spore germination
KPL75_RS01835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KPL75_RS01865	COG0456	acetyltransferase
KPL75_RS01865	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KPL75_RS01890	COG0730	response to heat
KPL75_RS01900	COG0833	amino acid
KPL75_RS01910	COG4335	DNA alkylation repair
KPL75_RS01935	COG0768	penicillin binding
KPL75_RS01945	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KPL75_RS01960	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
KPL75_RS01965	COG1984	allophanate hydrolase subunit 2
KPL75_RS01970	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KPL75_RS01975	COG1414	Transcriptional regulator
KPL75_RS01990	COG3142	Participates in the control of copper homeostasis
KPL75_RS01995	COG0860	N-Acetylmuramoyl-L-alanine amidase
KPL75_RS02000	COG0640	Transcriptional regulator
KPL75_RS02015	COG1960	acyl-CoA dehydrogenase activity
KPL75_RS02040	COG0640	Transcriptional regulator
KPL75_RS02045	COG3314	Sporulation integral membrane protein YlbJ
KPL75_RS02065	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KPL75_RS02085	COG0574	Belongs to the PEP-utilizing enzyme family
KPL75_RS02085	COG3848	Pyruvate phosphate dikinase
KPL75_RS02115	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KPL75_RS02120	COG0730	response to heat
KPL75_RS02155	COG1575	Belongs to the MenA family. Type 1 subfamily
KPL75_RS02170	COG0803	Belongs to the bacterial solute-binding protein 9 family
KPL75_RS02175	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KPL75_RS02180	COG1121	(ABC) transporter
KPL75_RS02200	COG0798	PFAM Bile acid sodium symporter
KPL75_RS02205	COG0346	lactoylglutathione lyase activity
KPL75_RS02210	COG0640	Transcriptional regulator
KPL75_RS02215	COG1028	Short-chain dehydrogenase reductase Sdr
KPL75_RS02220	COG1522	sequence-specific DNA binding
KPL75_RS02235	COG0346	lactoylglutathione lyase activity
KPL75_RS02240	COG3850	Histidine kinase
KPL75_RS02240	COG5002	protein histidine kinase activity
KPL75_RS02245	COG0745	RESPONSE REGULATOR receiver
KPL75_RS02305	COG0384	phenazine biosynthesis protein PhzF
KPL75_RS02310	COG2814	Major facilitator Superfamily
KPL75_RS02320	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KPL75_RS02325	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KPL75_RS02355	COG0789	Transcriptional regulator
KPL75_RS02365	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KPL75_RS02385	COG0277	FAD linked oxidase domain protein
KPL75_RS02395	COG0577	efflux transmembrane transporter activity
KPL75_RS02410	COG3850	Histidine kinase
KPL75_RS02410	COG5002	protein histidine kinase activity
KPL75_RS02425	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KPL75_RS02440	COG1619	proteins homologs of microcin C7 resistance protein MccF
KPL75_RS02455	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KPL75_RS02490	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KPL75_RS02510	COG2814	Major facilitator Superfamily
KPL75_RS02665	COG0477	Major facilitator Superfamily
KPL75_RS02675	COG1846	Transcriptional regulator
KPL75_RS02680	COG2814	Major facilitator Superfamily
KPL75_RS02700	COG2814	Major facilitator Superfamily
KPL75_RS02705	COG1309	transcriptional regulator
KPL75_RS02715	COG2357	RelA SpoT domain protein
KPL75_RS02725	COG2197	response regulator
KPL75_RS02755	COG3409	Peptidoglycan-binding domain 1 protein
KPL75_RS02755	COG5632	N-Acetylmuramoyl-L-alanine amidase
KPL75_RS02810	COG0657	acetylesterase activity
KPL75_RS02820	COG2814	Major facilitator Superfamily
KPL75_RS02825	COG1309	transcriptional regulator
KPL75_RS02840	COG0825	malonyl-CoA metabolic process
KPL75_RS02850	COG2205	protein histidine kinase activity
KPL75_RS02855	COG0745	RESPONSE REGULATOR receiver
KPL75_RS02860	COG0577	efflux transmembrane transporter activity
KPL75_RS02865	COG1136	(ABC) transporter
KPL75_RS02895	COG1136	(ABC) transporter
KPL75_RS02935	COG2031	fatty acid transporter
KPL75_RS02945	COG2249	NAD(P)H dehydrogenase (quinone) activity
KPL75_RS02995	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KPL75_RS03000	COG1288	antiporter activity
KPL75_RS03005	COG2356	endonuclease I
KPL75_RS03015	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KPL75_RS03020	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KPL75_RS03055	COG1785	Belongs to the alkaline phosphatase family
KPL75_RS03060	COG0778	Nitroreductase
KPL75_RS03065	COG1733	regulation of RNA biosynthetic process
KPL75_RS03085	COG1028	Short-chain dehydrogenase reductase Sdr
KPL75_RS03095	COG1131	(ABC) transporter
KPL75_RS03125	COG1011	Hydrolase
KPL75_RS03135	COG2365	Tyrosine phosphatase family
KPL75_RS03155	COG0346	lactoylglutathione lyase activity
KPL75_RS03160	COG1940	carbohydrate kinase activity
KPL75_RS03170	COG0110	maltose O-acetyltransferase activity
KPL75_RS03185	COG0628	permease
KPL75_RS03210	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KPL75_RS03220	COG0477	Major facilitator Superfamily
KPL75_RS03230	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
KPL75_RS03240	COG1253	flavin adenine dinucleotide binding
KPL75_RS03245	COG0789	Transcriptional regulator
KPL75_RS03250	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KPL75_RS03275	COG0697	spore germination
KPL75_RS03285	COG1357	PFAM Pentapeptide repeats (8 copies)
KPL75_RS03290	COG3813	Protein conserved in bacteria
KPL75_RS03300	COG2706	6-phosphogluconolactonase activity
KPL75_RS03305	COG1070	Carbohydrate kinase
KPL75_RS03315	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KPL75_RS03320	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KPL75_RS03325	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KPL75_RS03330	COG4702	Belongs to the UPF0303 family
KPL75_RS03360	COG1733	regulation of RNA biosynthetic process
KPL75_RS03365	COG2188	Transcriptional regulator
KPL75_RS03370	COG0673	inositol 2-dehydrogenase activity
KPL75_RS03390	COG2801	Transposase and inactivated derivatives
KPL75_RS03405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KPL75_RS03420	COG0494	nUDIX hydrolase
KPL75_RS03435	COG0384	phenazine biosynthesis protein PhzF
KPL75_RS03440	COG1028	Short-chain dehydrogenase reductase Sdr
KPL75_RS03450	COG0318	PFAM AMP-dependent synthetase and ligase
KPL75_RS03455	COG2249	NAD(P)H dehydrogenase (quinone) activity
KPL75_RS03460	COG1733	regulation of RNA biosynthetic process
KPL75_RS03475	COG1191	sigma factor activity
KPL75_RS03545	COG2197	response regulator
KPL75_RS03550	COG4585	Histidine kinase
KPL75_RS03580	COG0814	amino acid
KPL75_RS03615	COG1151	hydroxylamine reductase activity
KPL75_RS03655	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KPL75_RS03665	COG2072	flavoprotein involved in K transport
KPL75_RS03710	COG1695	Transcriptional regulator
KPL75_RS03715	COG0604	alcohol dehydrogenase
KPL75_RS03720	COG1113	amino acid transport
KPL75_RS03730	COG2814	Major facilitator Superfamily
KPL75_RS03740	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KPL75_RS03745	COG1012	belongs to the aldehyde dehydrogenase family
KPL75_RS03755	COG0534	Mate efflux family protein
KPL75_RS03760	COG1012	belongs to the aldehyde dehydrogenase family
KPL75_RS03765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KPL75_RS03780	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KPL75_RS03785	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KPL75_RS03800	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KPL75_RS03805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KPL75_RS03810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KPL75_RS03815	COG3739	integral membrane protein
KPL75_RS03835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KPL75_RS03850	COG0583	DNA-binding transcription factor activity
KPL75_RS03875	COG1193	negative regulation of DNA recombination
KPL75_RS03885	COG2162	N-hydroxyarylamine O-acetyltransferase activity
KPL75_RS03890	COG1164	Oligoendopeptidase f
KPL75_RS03915	COG3781	membrane
KPL75_RS03930	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KPL75_RS03940	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KPL75_RS03945	COG0640	Transcriptional regulator
KPL75_RS03950	COG0604	alcohol dehydrogenase
KPL75_RS03955	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KPL75_RS03960	COG0457	Tetratricopeptide repeat
KPL75_RS03965	COG2808	Putative FMN-binding domain
KPL75_RS03970	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KPL75_RS03980	COG0277	FAD linked oxidase domain protein
KPL75_RS04000	COG1285	pathogenesis
KPL75_RS04010	COG2514	catechol 2,3-dioxygenase activity
KPL75_RS04015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KPL75_RS04020	COG1126	abc transporter atp-binding protein
KPL75_RS04025	COG0765	amino acid transport
KPL75_RS04030	COG2720	vancomycin resistance protein
KPL75_RS04055	COG1278	Cold shock
KPL75_RS04065	COG0716	FMN binding
KPL75_RS04080	COG1051	belongs to the nudix hydrolase family
KPL75_RS04100	COG1028	Short-chain dehydrogenase reductase Sdr
KPL75_RS04110	COG0165	Argininosuccinate lyase
KPL75_RS04125	COG4145	pantothenate transmembrane transporter activity
KPL75_RS04135	COG1012	belongs to the aldehyde dehydrogenase family
KPL75_RS04140	COG1028	Short-chain dehydrogenase reductase Sdr
KPL75_RS04150	COG1657	PFAM Prenyltransferase squalene oxidase
KPL75_RS04155	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KPL75_RS04160	COG2962	Rard protein
KPL75_RS04165	COG3326	Membrane
KPL75_RS04170	COG0531	amino acid
KPL75_RS04200	COG2226	methyltransferase
KPL75_RS04205	COG4166	transmembrane transport
KPL75_RS04210	COG4166	transmembrane transport
KPL75_RS04215	COG4166	transmembrane transport
KPL75_RS04230	COG1595	DNA-templated transcription, initiation
KPL75_RS04240	COG1131	(ABC) transporter
KPL75_RS04260	COG0673	inositol 2-dehydrogenase activity
KPL75_RS04265	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KPL75_RS04270	COG0187	DNA topoisomerase II activity
KPL75_RS04275	COG1832	CoA-binding protein
KPL75_RS04280	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KPL75_RS04285	COG0745	RESPONSE REGULATOR receiver
KPL75_RS04295	COG1328	CTP reductase activity
KPL75_RS04295	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KPL75_RS04305	COG4841	protein insertion into membrane
KPL75_RS04310	COG0824	Thioesterase
KPL75_RS04345	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KPL75_RS04365	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KPL75_RS04395	COG2211	Major facilitator Superfamily
KPL75_RS04405	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KPL75_RS04420	COG0183	Belongs to the thiolase family
KPL75_RS04425	COG0318	PFAM AMP-dependent synthetase and ligase
KPL75_RS04430	COG1268	BioY protein
KPL75_RS04435	COG0318	PFAM AMP-dependent synthetase and ligase
KPL75_RS04450	COG1396	sequence-specific DNA binding
KPL75_RS04475	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
KPL75_RS04495	COG0830	nickel cation binding
KPL75_RS04535	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KPL75_RS04545	COG5002	protein histidine kinase activity
KPL75_RS04555	COG0400	carboxylic ester hydrolase activity
KPL75_RS04560	COG0346	lactoylglutathione lyase activity
KPL75_RS04565	COG0069	glutamate synthase activity
KPL75_RS04570	COG1902	pentaerythritol trinitrate reductase activity
KPL75_RS04575	COG1329	Transcriptional regulator
KPL75_RS04580	COG0010	Belongs to the arginase family
KPL75_RS04590	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KPL75_RS04595	COG2986	histidine ammonia-lyase
KPL75_RS04605	COG2226	methyltransferase
KPL75_RS04630	COG4846	Membrane protein involved in cytochrome C biogenesis
KPL75_RS04635	COG0785	Cytochrome C biogenesis protein
KPL75_RS04645	COG1473	amidohydrolase
KPL75_RS04655	COG1131	(ABC) transporter
KPL75_RS04665	COG0583	DNA-binding transcription factor activity
KPL75_RS04675	COG1346	cytolysis
KPL75_RS04690	COG0730	response to heat
KPL75_RS04715	COG1132	(ABC) transporter
KPL75_RS04720	COG1132	(ABC) transporter
KPL75_RS04725	COG3763	UPF0154 protein
KPL75_RS04745	COG3639	organic phosphonate transmembrane transporter activity
KPL75_RS04755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KPL75_RS04760	COG0737	Belongs to the 5'-nucleotidase family
KPL75_RS04770	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KPL75_RS04775	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KPL75_RS04790	COG1695	Transcriptional regulator
KPL75_RS04800	COG0174	glutamine synthetase
KPL75_RS04805	COG0789	Transcriptional regulator
KPL75_RS04810	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KPL75_RS04815	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KPL75_RS04820	COG2860	membrane
KPL75_RS04830	COG0464	growth
KPL75_RS04850	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KPL75_RS04860	COG1388	LysM domain
KPL75_RS04860	COG3584	3D domain protein
KPL75_RS04865	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KPL75_RS04865	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KPL75_RS04865	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KPL75_RS04870	COG1105	Belongs to the carbohydrate kinase PfkB family
KPL75_RS04875	COG1349	DNA-binding transcription factor activity
KPL75_RS04880	COG1979	alcohol dehydrogenase
KPL75_RS04885	COG2322	membrane
KPL75_RS04895	COG1113	amino acid transport
KPL75_RS04905	COG1473	amidohydrolase
KPL75_RS04910	COG1408	metallophosphoesterase
KPL75_RS04915	COG2116	formate transmembrane transporter activity
KPL75_RS04925	COG0454	-acetyltransferase
KPL75_RS04930	COG2217	Heavy metal translocating P-type atpase
KPL75_RS04940	COG1937	Protein conserved in bacteria
KPL75_RS04970	COG2819	hydrolase of the alpha beta superfamily
KPL75_RS04975	COG1120	ATPase activity
KPL75_RS04980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KPL75_RS04985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KPL75_RS04990	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KPL75_RS05000	COG0708	Exodeoxyribonuclease III
KPL75_RS05005	COG2169	Transcriptional regulator
KPL75_RS05010	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KPL75_RS05015	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KPL75_RS05020	COG2195	Cleaves the N-terminal amino acid of tripeptides
KPL75_RS05025	COG2364	Membrane
KPL75_RS05045	COG0346	lactoylglutathione lyase activity
KPL75_RS05050	COG5001	Diguanylate cyclase
KPL75_RS05050	COG3300	MHYT domain
KPL75_RS05085	COG1346	cytolysis
KPL75_RS05095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KPL75_RS05100	COG2945	thiolester hydrolase activity
KPL75_RS05100	COG0596	Alpha beta hydrolase
KPL75_RS05105	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KPL75_RS05115	COG2188	Transcriptional regulator
KPL75_RS05120	COG2723	6-phospho-beta-galactosidase activity
KPL75_RS05130	COG3773	Cell wall hydrolase
KPL75_RS05140	COG1368	sulfuric ester hydrolase activity
KPL75_RS05155	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KPL75_RS05160	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KPL75_RS05175	COG4550	Control of competence regulator ComK, YlbF/YmcA
KPL75_RS05180	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KPL75_RS05185	COG1013	pyruvate-flavodoxin oxidoreductase activity
KPL75_RS05190	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KPL75_RS05190	COG0674	pyruvate-flavodoxin oxidoreductase activity
KPL75_RS05200	COG2359	stage V sporulation protein S
KPL75_RS05205	COG1692	metallophosphoesterase
KPL75_RS05210	COG1418	mRNA catabolic process
KPL75_RS05215	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KPL75_RS05220	COG1546	Belongs to the CinA family
KPL75_RS05220	COG1058	Belongs to the CinA family
KPL75_RS05225	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KPL75_RS05230	COG1426	Protein conserved in bacteria
KPL75_RS05245	COG0300	oxidoreductase activity
KPL75_RS05250	COG0612	Peptidase, M16
KPL75_RS05255	COG0612	Peptidase, M16
KPL75_RS05260	COG1079	Belongs to the binding-protein-dependent transport system permease family
KPL75_RS05265	COG4603	Belongs to the binding-protein-dependent transport system permease family
KPL75_RS05270	COG3845	ABC transporter
KPL75_RS05275	COG1744	ABC transporter substrate-binding protein PnrA-like
KPL75_RS05280	COG2188	Transcriptional regulator
KPL75_RS05290	COG1674	ftsk spoiiie
KPL75_RS05300	COG0740	serine-type endopeptidase activity
KPL75_RS05305	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KPL75_RS05315	COG0527	aspartate kinase activity
KPL75_RS05320	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KPL75_RS05460	COG0582	viral genome integration into host DNA
KPL75_RS05495	COG0305	Participates in initiation and elongation during chromosome replication
KPL75_RS05540	COG1396	sequence-specific DNA binding
KPL75_RS05555	COG2856	Zn peptidase
KPL75_RS05570	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KPL75_RS05575	COG1873	PFAM PRC-barrel domain
KPL75_RS05580	COG0612	Peptidase, M16
KPL75_RS05585	COG0726	polysaccharide deacetylase
KPL75_RS05590	COG1185	polyribonucleotide nucleotidyltransferase activity
KPL75_RS05600	COG0196	riboflavin kinase activity
KPL75_RS05610	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KPL75_RS05615	COG1550	Protein conserved in bacteria
KPL75_RS05620	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KPL75_RS05625	COG1358	cellular component organization or biogenesis
KPL75_RS05630	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KPL75_RS05635	COG0195	Participates in both transcription termination and antitermination
KPL75_RS05640	COG0779	Required for maturation of 30S ribosomal subunits
KPL75_RS05650	COG0442	prolyl-tRNA aminoacylation
KPL75_RS05655	COG0750	zinc metalloprotease
KPL75_RS05665	COG4589	Belongs to the CDS family
KPL75_RS05675	COG0233	cytoplasmic translational termination
KPL75_RS05680	COG0528	UMP kinase activity
KPL75_RS05685	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KPL75_RS05695	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KPL75_RS05700	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KPL75_RS05705	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KPL75_RS05710	COG4974	Belongs to the 'phage' integrase family
KPL75_RS05715	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KPL75_RS05720	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KPL75_RS05725	COG0758	DNA mediated transformation
KPL75_RS05730	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KPL75_RS05735	COG0045	succinate-CoA ligase (ADP-forming) activity
KPL75_RS05740	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KPL75_RS05755	COG0335	large ribosomal subunit rRNA binding
KPL75_RS05760	COG0336	Belongs to the RNA methyltransferase TrmD family
KPL75_RS05765	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KPL75_RS05770	COG1837	Belongs to the UPF0109 family
KPL75_RS05780	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KPL75_RS05790	COG0552	protein localization to endoplasmic reticulum
KPL75_RS05795	COG1196	nuclear chromosome segregation
KPL75_RS05800	COG0571	ribonuclease III activity
KPL75_RS05805	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KPL75_RS05810	COG1028	Short-chain dehydrogenase reductase Sdr
KPL75_RS05815	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KPL75_RS05830	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KPL75_RS05835	COG1461	Dihydroxyacetone kinase
KPL75_RS05840	COG1302	Protein conserved in bacteria
KPL75_RS05855	COG1564	THIamine pyrophosphokinase
KPL75_RS05860	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KPL75_RS05870	COG0515	serine threonine protein kinase
KPL75_RS05870	COG2815	serine threonine protein kinase
KPL75_RS05875	COG0631	protein serine/threonine phosphatase activity
KPL75_RS05880	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KPL75_RS05885	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KPL75_RS05885	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KPL75_RS05890	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KPL75_RS05895	COG0242	peptide deformylase activity
KPL75_RS05900	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KPL75_RS05905	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KPL75_RS05910	COG1758	RNA polymerase activity
KPL75_RS05925	COG1561	YicC-like family, N-terminal region
KPL75_RS05930	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KPL75_RS05945	COG0006	proline dipeptidase activity
KPL75_RS05965	COG3069	C4-dicarboxylate transmembrane transporter activity
KPL75_RS05965	COG3069	C4-dicarboxylate transmembrane transporter activity
KPL75_RS06025	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KPL75_RS06030	COG0564	pseudouridine synthase activity
KPL75_RS06050	COG3599	regulation of cell shape
KPL75_RS06055	COG2302	S4 RNA-binding domain
KPL75_RS06060	COG0762	integral membrane protein
KPL75_RS06065	COG1799	cell septum assembly
KPL75_RS06070	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KPL75_RS06080	COG1873	PFAM PRC-barrel domain
KPL75_RS06085	COG1191	sigma factor activity
KPL75_RS06090	COG1191	sigma factor activity
KPL75_RS06100	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KPL75_RS06105	COG0849	cell division
KPL75_RS06110	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KPL75_RS06125	COG0772	Belongs to the SEDS family
KPL75_RS06130	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KPL75_RS06135	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KPL75_RS06140	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KPL75_RS06145	COG0768	penicillin binding
KPL75_RS06150	COG0768	penicillin binding
KPL75_RS06160	COG0275	rRNA processing
KPL75_RS06165	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
KPL75_RS06170	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KPL75_RS06175	COG0454	-acetyltransferase
KPL75_RS06185	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KPL75_RS06190	COG1399	metal-binding, possibly nucleic acid-binding protein
KPL75_RS06195	COG1323	Belongs to the UPF0348 family
KPL75_RS06200	COG3480	Lon protease (S16) C-terminal proteolytic domain
KPL75_RS06205	COG1752	Esterase of the alpha-beta hydrolase superfamily
KPL75_RS06210	COG3314	Sporulation integral membrane protein YlbJ
KPL75_RS06220	COG0742	ribosomal rna small subunit methyltransferase
KPL75_RS06230	COG4471	UPF0298 protein
KPL75_RS06235	COG3679	Belongs to the UPF0342 family
KPL75_RS06240	COG0406	alpha-ribazole phosphatase activity
KPL75_RS06255	COG2340	Cysteine-rich secretory protein family
KPL75_RS06270	COG3336	cytochrome c oxidase
KPL75_RS06295	COG0109	protoheme IX farnesyltransferase activity
KPL75_RS06300	COG1612	heme a metabolic process
KPL75_RS06305	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KPL75_RS06310	COG0772	Belongs to the SEDS family
KPL75_RS06315	COG4838	Belongs to the UPF0358 family
KPL75_RS06320	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KPL75_RS06325	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KPL75_RS06335	COG4896	Protein conserved in bacteria
KPL75_RS06350	COG1217	gtp-binding protein TYPA
KPL75_RS06360	COG0483	inositol monophosphate 1-phosphatase activity
KPL75_RS06370	COG4493	Belongs to the UPF0637 family
KPL75_RS06375	COG4476	Belongs to the UPF0223 family
KPL75_RS06380	COG1982	Orn Lys Arg decarboxylase major
KPL75_RS06430	COG0022	dehydrogenase e1 component
KPL75_RS06435	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KPL75_RS06450	COG0561	phosphatase activity
KPL75_RS06455	COG5503	Protein of unknown function (DUF1447)
KPL75_RS06460	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KPL75_RS06465	COG0569	domain protein
KPL75_RS06475	COG1473	amidohydrolase
KPL75_RS06480	COG2171	N-acyltransferase activity
KPL75_RS06485	COG0583	DNA-binding transcription factor activity
KPL75_RS06490	COG0517	IMP dehydrogenase activity
KPL75_RS06500	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KPL75_RS06510	COG4703	Protein of unknown function (DUF1797)
KPL75_RS06525	COG2200	EAL domain
KPL75_RS06530	COG1028	Short-chain dehydrogenase reductase Sdr
KPL75_RS06535	COG1408	metallophosphoesterase
KPL75_RS06580	COG2814	Major facilitator Superfamily
KPL75_RS06590	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KPL75_RS06600	COG3209	COG3209 Rhs family protein
KPL75_RS06610	COG2205	protein histidine kinase activity
KPL75_RS06620	COG0436	Aminotransferase
KPL75_RS06625	COG1609	Transcriptional regulator
KPL75_RS06630	COG3833	ABC-type maltose transport systems, permease component
KPL75_RS06635	COG1175	transmembrane transport
KPL75_RS06640	COG2182	Extracellular solute-binding protein
KPL75_RS06650	COG0366	Alpha amylase catalytic
KPL75_RS06655	COG3842	ATPase activity
KPL75_RS06695	COG0183	Belongs to the thiolase family
KPL75_RS06725	COG1695	Transcriptional regulator
KPL75_RS06730	COG1028	Short-chain dehydrogenase reductase Sdr
KPL75_RS06740	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KPL75_RS06745	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
KPL75_RS06750	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KPL75_RS06755	COG0436	Aminotransferase
KPL75_RS06765	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
KPL75_RS06770	COG0235	Class ii aldolase
KPL75_RS06775	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KPL75_RS06790	COG2084	Dehydrogenase
KPL75_RS06800	COG2199	diguanylate cyclase activity
KPL75_RS06805	COG0778	Nitroreductase
KPL75_RS06830	COG2190	(PTS) system
KPL75_RS06830	COG1263	PTS System
KPL75_RS06830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KPL75_RS06835	COG3711	transcriptional antiterminator
KPL75_RS06845	COG2188	Transcriptional regulator
KPL75_RS06850	COG0363	glucosamine-6-phosphate deaminase activity
KPL75_RS06865	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KPL75_RS06870	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KPL75_RS06880	COG1547	Domain of unknown function (DUF309)
KPL75_RS06890	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KPL75_RS06895	COG4086	secreted protein
KPL75_RS06900	COG0561	phosphatase activity
KPL75_RS06905	COG0697	spore germination
KPL75_RS06920	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KPL75_RS06960	COG1686	Belongs to the peptidase S11 family
KPL75_RS06965	COG1725	Transcriptional regulator
KPL75_RS06970	COG1131	(ABC) transporter
KPL75_RS06995	COG1846	Transcriptional regulator
KPL75_RS07010	COG0598	Magnesium transport protein CorA
KPL75_RS07035	COG4974	Belongs to the 'phage' integrase family
KPL75_RS07045	COG0735	belongs to the Fur family
KPL75_RS07050	COG1300	Membrane
KPL75_RS07070	COG0667	Aldo Keto reductase
KPL75_RS07075	COG0656	L-ascorbic acid biosynthetic process
KPL75_RS07080	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KPL75_RS07080	COG0456	acetyltransferase
KPL75_RS07090	COG0737	Belongs to the 5'-nucleotidase family
KPL75_RS07090	COG1525	nuclease
KPL75_RS07090	COG4085	toxin activity
KPL75_RS07105	COG0596	Alpha beta hydrolase
KPL75_RS07110	COG2056	Na+-H+ antiporter family
KPL75_RS07115	COG1609	Transcriptional regulator
KPL75_RS07120	COG0456	acetyltransferase
KPL75_RS07125	COG1073	alpha beta
KPL75_RS07140	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KPL75_RS07140	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KPL75_RS07145	COG0307	riboflavin synthase, alpha
KPL75_RS07150	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KPL75_RS07150	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KPL75_RS07165	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KPL75_RS07175	COG2226	methyltransferase
KPL75_RS07175	COG1073	alpha beta
KPL75_RS07180	COG0156	8-amino-7-oxononanoate synthase activity
KPL75_RS07190	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KPL75_RS07200	COG1757	Na H antiporter
KPL75_RS07205	COG0737	Belongs to the 5'-nucleotidase family
KPL75_RS07215	COG1522	sequence-specific DNA binding
KPL75_RS07235	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KPL75_RS07260	COG0300	oxidoreductase activity
KPL75_RS07265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KPL75_RS07270	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KPL75_RS07275	COG1760	l-serine dehydratase
KPL75_RS07280	COG1760	l-serine dehydratase
KPL75_RS07295	COG1234	tRNA 3'-trailer cleavage
KPL75_RS07310	COG1285	pathogenesis
KPL75_RS07330	COG2195	Cleaves the N-terminal amino acid of tripeptides
KPL75_RS07335	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KPL75_RS07350	COG1376	ErfK ybiS ycfS ynhG family protein
KPL75_RS07355	COG4129	membrane
KPL75_RS07360	COG1126	abc transporter atp-binding protein
KPL75_RS07365	COG0765	amino acid transport
KPL75_RS07370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KPL75_RS07385	COG2816	NAD+ diphosphatase activity
KPL75_RS07390	COG2323	membrane
KPL75_RS07395	COG0772	Belongs to the SEDS family
KPL75_RS07400	COG0508	dehydrogenase complex catalyzes the overall conversion of
KPL75_RS07405	COG0022	dehydrogenase e1 component
KPL75_RS07410	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KPL75_RS07415	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KPL75_RS07420	COG3426	butyrate kinase activity
KPL75_RS07430	COG0280	phosphate acetyltransferase
KPL75_RS07435	COG3290	protein histidine kinase activity
KPL75_RS07435	COG3829	transcription factor binding
KPL75_RS07445	COG0584	glycerophosphoryl diester phosphodiesterase
KPL75_RS07450	COG3093	addiction module antidote protein HigA
KPL75_RS07555	COG0745	RESPONSE REGULATOR receiver
KPL75_RS07560	COG0750	zinc metalloprotease
KPL75_RS07565	COG0497	DNA recombination
KPL75_RS07570	COG1438	arginine binding
KPL75_RS07575	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KPL75_RS07580	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KPL75_RS07585	COG0142	geranyltranstransferase activity
KPL75_RS07590	COG1722	exodeoxyribonuclease VII activity
KPL75_RS07595	COG1570	exodeoxyribonuclease VII activity
KPL75_RS07600	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KPL75_RS07605	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KPL75_RS07610	COG1302	Protein conserved in bacteria
KPL75_RS07615	COG0439	Biotin carboxylase
KPL75_RS07620	COG0511	ligase activity, forming carbon-carbon bonds
KPL75_RS07665	COG3854	ATPases associated with a variety of cellular activities
KPL75_RS07685	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KPL75_RS07690	COG0006	proline dipeptidase activity
KPL75_RS07705	COG3872	metal-dependent enzyme
KPL75_RS07715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KPL75_RS07750	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KPL75_RS07760	COG1609	Transcriptional regulator
KPL75_RS07770	COG2076	Multidrug Resistance protein
KPL75_RS07775	COG2076	Multidrug Resistance protein
KPL75_RS07815	COG1725	Transcriptional regulator
KPL75_RS07830	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KPL75_RS07835	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KPL75_RS07840	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KPL75_RS07845	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KPL75_RS07860	COG2801	Transposase and inactivated derivatives
KPL75_RS07885	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KPL75_RS07910	COG4970	Tfp pilus assembly protein FimT
KPL75_RS07920	COG1459	type II secretion system
KPL75_RS07925	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KPL75_RS07980	COG0646	methionine synthase
KPL75_RS07980	COG1410	methionine synthase
KPL75_RS07985	COG0646	methionine synthase
KPL75_RS07985	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KPL75_RS07990	COG0626	cystathionine gamma-synthase activity
KPL75_RS07995	COG0626	cystathionine gamma-synthase activity
KPL75_RS08015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KPL75_RS08025	COG1940	carbohydrate kinase activity
KPL75_RS08030	COG4483	Protein conserved in bacteria
KPL75_RS08035	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KPL75_RS08040	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KPL75_RS08045	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KPL75_RS08050	COG0704	Plays a role in the regulation of phosphate uptake
KPL75_RS08060	COG0581	inorganic phosphate transmembrane transporter activity
KPL75_RS08065	COG0573	inorganic phosphate transmembrane transporter activity
KPL75_RS08070	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KPL75_RS08075	COG0768	penicillin binding
KPL75_RS08080	COG0477	Major facilitator Superfamily
KPL75_RS08085	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KPL75_RS08105	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KPL75_RS08110	COG0735	belongs to the Fur family
KPL75_RS08115	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KPL75_RS08120	COG1121	(ABC) transporter
KPL75_RS08125	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KPL75_RS08135	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KPL75_RS08155	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KPL75_RS08160	COG2384	SAM-dependent methyltransferase
KPL75_RS08165	COG2010	Cytochrome c
KPL75_RS08170	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KPL75_RS08175	COG0358	DNA primase activity
KPL75_RS08185	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KPL75_RS08190	COG0517	IMP dehydrogenase activity
KPL75_RS08195	COG1381	Involved in DNA repair and RecF pathway recombination
KPL75_RS08205	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KPL75_RS08210	COG0295	cytidine deaminase activity
KPL75_RS08215	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KPL75_RS08220	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KPL75_RS08225	COG1480	7TM receptor with intracellular HD hydrolase
KPL75_RS08230	COG1702	phosphate starvation-inducible protein PhoH
KPL75_RS08245	COG1610	YqeY-like protein
KPL75_RS08250	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KPL75_RS08255	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KPL75_RS08260	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KPL75_RS08270	COG0484	heat shock protein binding
KPL75_RS08275	COG0443	Heat shock 70 kDa protein
KPL75_RS08285	COG1420	regulation of RNA biosynthetic process
KPL75_RS08295	COG1733	regulation of RNA biosynthetic process
KPL75_RS08300	COG0481	GTPase activity
KPL75_RS08310	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
KPL75_RS08315	COG0268	Binds directly to 16S ribosomal RNA
KPL75_RS08320	COG1466	dna polymerase III delta subunit
KPL75_RS08330	COG0658	competence protein
KPL75_RS08330	COG2333	competence protein COMEC
KPL75_RS08335	COG2131	deaminase
KPL75_RS08340	COG1555	photosystem II stabilization
KPL75_RS08340	COG1596	polysaccharide export
KPL75_RS08345	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KPL75_RS08350	COG2226	methyltransferase
KPL75_RS08355	COG0799	negative regulation of ribosome biogenesis
KPL75_RS08360	COG1713	HD superfamily hydrolase involved in NAD metabolism
KPL75_RS08365	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KPL75_RS08370	COG1534	Rna-binding protein
KPL75_RS08375	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KPL75_RS08380	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KPL75_RS08385	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KPL75_RS08395	COG0688	phosphatidylethanolamine metabolic process
KPL75_RS08415	COG2357	RelA SpoT domain protein
KPL75_RS08425	COG1785	Belongs to the alkaline phosphatase family
KPL75_RS08435	COG2267	carboxylic ester hydrolase activity
KPL75_RS08475	COG3186	Phenylalanine-4-hydroxylase
KPL75_RS08480	COG2154	pterin-4-alpha-carbinolamine dehydratase
KPL75_RS08485	COG2801	Transposase and inactivated derivatives
KPL75_RS08495	COG2514	catechol 2,3-dioxygenase activity
KPL75_RS08500	COG2259	Doxx family
KPL75_RS08540	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KPL75_RS08550	COG1012	belongs to the aldehyde dehydrogenase family
KPL75_RS08550	COG1454	alcohol dehydrogenase
KPL75_RS08555	COG0626	cystathionine gamma-synthase activity
KPL75_RS08560	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KPL75_RS08565	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KPL75_RS08570	COG2226	methyltransferase
KPL75_RS08585	COG0768	penicillin binding
KPL75_RS08595	COG0572	uridine kinase
KPL75_RS08600	COG0826	peptidase U32
KPL75_RS08605	COG0826	peptidase U32
KPL75_RS08610	COG4122	O-methyltransferase activity
KPL75_RS08615	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KPL75_RS08625	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KPL75_RS08635	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KPL75_RS08645	COG0628	permease
KPL75_RS08665	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KPL75_RS08675	COG0482	sulfurtransferase activity
KPL75_RS08680	COG1104	cysteine desulfurase activity
KPL75_RS08685	COG1959	2 iron, 2 sulfur cluster binding
KPL75_RS08690	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KPL75_RS08700	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KPL75_RS08735	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KPL75_RS08740	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KPL75_RS08745	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KPL75_RS08745	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KPL75_RS08750	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KPL75_RS08755	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KPL75_RS08755	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KPL75_RS08765	COG2244	polysaccharide biosynthetic process
KPL75_RS08770	COG2323	membrane
KPL75_RS08780	COG1862	Preprotein translocase
KPL75_RS08800	COG2255	four-way junction helicase activity
KPL75_RS08805	COG0632	four-way junction helicase activity
KPL75_RS08810	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KPL75_RS08820	COG0697	spore germination
KPL75_RS08825	COG0640	Transcriptional regulator
KPL75_RS08830	COG2801	Transposase and inactivated derivatives
KPL75_RS08855	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KPL75_RS08860	COG0157	Belongs to the NadC ModD family
KPL75_RS08865	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KPL75_RS08870	COG1104	cysteine desulfurase activity
KPL75_RS08875	COG1827	regulation of RNA biosynthetic process
KPL75_RS08880	COG2258	MOSC domain
KPL75_RS08885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KPL75_RS08890	COG0077	Prephenate dehydratase
KPL75_RS08895	COG0577	efflux transmembrane transporter activity
KPL75_RS08900	COG0577	efflux transmembrane transporter activity
KPL75_RS08905	COG1136	(ABC) transporter
KPL75_RS08910	COG5002	protein histidine kinase activity
KPL75_RS08915	COG0745	RESPONSE REGULATOR receiver
KPL75_RS08920	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KPL75_RS08925	COG3290	protein histidine kinase activity
KPL75_RS08935	COG2868	ribosomal protein
KPL75_RS08945	COG1530	ribonuclease E activity
KPL75_RS08950	COG1994	Peptidase M50
KPL75_RS08955	COG0739	heme binding
KPL75_RS08960	COG2894	cell division
KPL75_RS08965	COG0850	regulation of cytokinetic process
KPL75_RS08980	COG1077	Cell shape determining protein MreB Mrl
KPL75_RS08985	COG2003	Belongs to the UPF0758 family
KPL75_RS08990	COG0424	maF-like protein
KPL75_RS09000	COG0285	dihydrofolate synthase activity
KPL75_RS09015	COG1388	LysM domain
KPL75_RS09020	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KPL75_RS09025	COG0113	porphobilinogen synthase activity
KPL75_RS09030	COG1587	Uroporphyrinogen-III synthase
KPL75_RS09035	COG0181	hydroxymethylbilane synthase activity
KPL75_RS09040	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KPL75_RS09045	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KPL75_RS09050	COG1846	Transcriptional regulator
KPL75_RS09055	COG1764	response to oxidative stress
KPL75_RS09060	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KPL75_RS09070	COG1067	ATP-dependent peptidase activity
KPL75_RS09070	COG0470	DNA polymerase III
KPL75_RS09080	COG0544	peptidyl-prolyl cis-trans isomerase activity
KPL75_RS09110	COG0622	Phosphoesterase
KPL75_RS09120	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KPL75_RS09125	COG5401	PFAM Sporulation and spore germination
KPL75_RS09135	COG2197	response regulator
KPL75_RS09140	COG2233	PERMEase
KPL75_RS09145	COG0402	S-adenosylhomocysteine deaminase activity
KPL75_RS09150	COG1983	PspC domain protein
KPL75_RS09155	COG1396	sequence-specific DNA binding
KPL75_RS09160	COG0697	spore germination
KPL75_RS09170	COG1959	2 iron, 2 sulfur cluster binding
KPL75_RS09175	COG1668	transmembrane transport
KPL75_RS09180	COG4152	abc transporter atp-binding protein
KPL75_RS09185	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
KPL75_RS09190	COG1360	Flagellar Motor Protein
KPL75_RS09195	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KPL75_RS09200	COG1876	peptidase activity
KPL75_RS09205	COG0824	Thioesterase
KPL75_RS09210	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KPL75_RS09215	COG1053	succinate dehydrogenase
KPL75_RS09220	COG2009	succinate dehydrogenase
KPL75_RS09225	COG1719	4-vinyl reductase, 4VR
KPL75_RS09230	COG0322	excinuclease ABC activity
KPL75_RS09235	COG3118	belongs to the thioredoxin family
KPL75_RS09240	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KPL75_RS09245	COG2086	electron transfer activity
KPL75_RS09250	COG1024	Enoyl-CoA hydratase
KPL75_RS09255	COG1309	transcriptional regulator
KPL75_RS09260	COG0318	PFAM AMP-dependent synthetase and ligase
KPL75_RS09270	COG2318	DinB family
KPL75_RS09300	COG1131	(ABC) transporter
KPL75_RS09305	COG2205	protein histidine kinase activity
KPL75_RS09310	COG0745	RESPONSE REGULATOR receiver
KPL75_RS09320	COG4895	conserved protein (DUF2196)
KPL75_RS09325	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KPL75_RS09335	COG4509	Sortase family
KPL75_RS09340	COG1120	ATPase activity
KPL75_RS09355	COG5386	Cell surface protein
KPL75_RS09365	COG5386	Cell surface protein
KPL75_RS09370	COG1114	Component of the transport system for branched-chain amino acids
KPL75_RS09380	COG1193	negative regulation of DNA recombination
KPL75_RS09385	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KPL75_RS09385	COG1796	DNA polymerase
KPL75_RS09390	COG1286	toxin biosynthetic process
KPL75_RS09395	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KPL75_RS09400	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KPL75_RS09420	COG1028	Short-chain dehydrogenase reductase Sdr
KPL75_RS09435	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KPL75_RS09440	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KPL75_RS09450	COG1418	mRNA catabolic process
KPL75_RS09470	COG2814	Major facilitator Superfamily
KPL75_RS09475	COG1566	PFAM secretion protein HlyD family protein
KPL75_RS09480	COG1309	transcriptional regulator
KPL75_RS09485	COG1363	Peptidase, m42
KPL75_RS09495	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KPL75_RS09510	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KPL75_RS09520	COG1484	DNA-dependent DNA replication
KPL75_RS09525	COG3611	Membrane attachment protein
KPL75_RS09530	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KPL75_RS09535	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KPL75_RS09540	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KPL75_RS09550	COG1971	Probably functions as a manganese efflux pump
KPL75_RS09560	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KPL75_RS09560	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KPL75_RS09565	COG5002	protein histidine kinase activity
KPL75_RS09570	COG0745	RESPONSE REGULATOR receiver
KPL75_RS09590	COG0538	isocitrate dehydrogenase activity
KPL75_RS09595	COG0372	Belongs to the citrate synthase family
KPL75_RS09605	COG0628	permease
KPL75_RS09610	COG3030	protein affecting phage T7 exclusion by the F plasmid
KPL75_RS09620	COG0205	6-phosphofructokinase activity
KPL75_RS09630	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KPL75_RS09635	COG1725	Transcriptional regulator
KPL75_RS09640	COG0281	malic enzyme
KPL75_RS09645	COG0587	DNA-directed DNA polymerase activity
KPL75_RS09660	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KPL75_RS09675	COG4109	DRTGG domain
KPL75_RS09690	COG0006	proline dipeptidase activity
KPL75_RS09730	COG0662	Cupin 2, conserved barrel domain protein
KPL75_RS09745	COG1028	Short-chain dehydrogenase reductase Sdr
KPL75_RS09750	COG0589	response to stress
KPL75_RS09770	COG0165	Argininosuccinate lyase
KPL75_RS09775	COG0137	argininosuccinate synthase activity
KPL75_RS09790	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KPL75_RS09810	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KPL75_RS09815	COG0827	DNA restriction-modification system
KPL75_RS09820	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KPL75_RS09825	COG3874	Sporulation protein YtfJ
KPL75_RS09840	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KPL75_RS09850	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KPL75_RS09865	COG1104	cysteine desulfurase activity
KPL75_RS09870	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KPL75_RS09875	COG0583	DNA-binding transcription factor activity
KPL75_RS09880	COG0697	spore germination
KPL75_RS09885	COG1309	transcriptional regulator
KPL75_RS09890	COG1956	GAF domain-containing protein
KPL75_RS09895	COG0626	cystathionine gamma-synthase activity
KPL75_RS09900	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KPL75_RS09925	COG1595	DNA-templated transcription, initiation
KPL75_RS09935	COG0110	maltose O-acetyltransferase activity
KPL75_RS09945	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KPL75_RS09950	COG0454	-acetyltransferase
KPL75_RS09955	COG0517	IMP dehydrogenase activity
KPL75_RS09960	COG0123	including yeast histone deacetylase and acetoin utilization protein
KPL75_RS09965	COG2267	carboxylic ester hydrolase activity
KPL75_RS09980	COG0673	inositol 2-dehydrogenase activity
KPL75_RS09985	COG1970	mechanosensitive ion channel activity
KPL75_RS10005	COG1609	Transcriptional regulator
KPL75_RS10010	COG4851	CamS sex pheromone cAM373 precursor
KPL75_RS10015	COG3118	belongs to the thioredoxin family
KPL75_RS10025	COG2309	aminopeptidase activity
KPL75_RS10050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KPL75_RS10055	COG0697	spore germination
KPL75_RS10060	COG0789	Transcriptional regulator
KPL75_RS10065	COG1695	Transcriptional regulator
KPL75_RS10075	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KPL75_RS10085	COG1674	ftsk spoiiie
KPL75_RS10100	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KPL75_RS10105	COG4848	Belongs to the UPF0354 family
KPL75_RS10110	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KPL75_RS10115	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
KPL75_RS10120	COG1363	Peptidase, m42
KPL75_RS10130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KPL75_RS10135	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KPL75_RS10145	COG0510	thiamine kinase activity
KPL75_RS10150	COG1523	belongs to the glycosyl hydrolase 13 family
KPL75_RS10160	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KPL75_RS10165	COG1349	DNA-binding transcription factor activity
KPL75_RS10170	COG1187	pseudouridine synthase activity
KPL75_RS10175	COG2244	polysaccharide biosynthetic process
KPL75_RS10180	COG2081	HI0933 family
KPL75_RS10185	COG2814	Major facilitator Superfamily
KPL75_RS10195	COG3832	glyoxalase III activity
KPL75_RS10215	COG1329	Transcriptional regulator
KPL75_RS10240	COG0314	molybdopterin synthase activity
KPL75_RS10245	COG1763	Mo-molybdopterin cofactor biosynthetic process
KPL75_RS10250	COG0303	'Molybdopterin
KPL75_RS10255	COG0315	cyclic pyranopterin monophosphate synthase activity
KPL75_RS10260	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KPL75_RS10265	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KPL75_RS10285	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KPL75_RS10295	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KPL75_RS10340	COG2814	Major facilitator Superfamily
KPL75_RS10345	COG0475	glutathione-regulated potassium exporter activity
KPL75_RS10350	COG0490	domain, Protein
KPL75_RS10355	COG0582	viral genome integration into host DNA
KPL75_RS10370	COG1136	(ABC) transporter
KPL75_RS10390	COG1242	4 iron, 4 sulfur cluster binding
KPL75_RS10395	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KPL75_RS10400	COG1794	racemase activity, acting on amino acids and derivatives
KPL75_RS10415	COG2267	carboxylic ester hydrolase activity
KPL75_RS10420	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KPL75_RS10425	COG0671	phosphoesterase, PA-phosphatase related
KPL75_RS10430	COG0438	transferase activity, transferring glycosyl groups
KPL75_RS10455	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KPL75_RS10460	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KPL75_RS10500	COG5002	protein histidine kinase activity
KPL75_RS10505	COG3852	Histidine kinase
KPL75_RS10510	COG0753	catalase activity
KPL75_RS10515	COG2267	carboxylic ester hydrolase activity
KPL75_RS10525	COG1368	sulfuric ester hydrolase activity
KPL75_RS10535	COG4895	conserved protein (DUF2196)
KPL75_RS10555	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KPL75_RS10560	COG1116	anion transmembrane transporter activity
KPL75_RS10565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KPL75_RS10585	COG0494	nUDIX hydrolase
KPL75_RS10620	COG1854	S-ribosylhomocysteine lyase activity
KPL75_RS10630	COG0288	reversible hydration of carbon dioxide
KPL75_RS10635	COG1271	oxidase subunit
KPL75_RS10640	COG1294	oxidase, subunit
KPL75_RS10660	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KPL75_RS10685	COG1842	Phage shock protein A
KPL75_RS10710	COG3859	Proton-coupled thiamine transporter YuaJ
KPL75_RS10715	COG5002	protein histidine kinase activity
KPL75_RS10720	COG0745	RESPONSE REGULATOR receiver
KPL75_RS10745	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KPL75_RS10750	COG1597	lipid kinase activity
KPL75_RS10765	COG1136	(ABC) transporter
KPL75_RS10780	COG5002	protein histidine kinase activity
KPL75_RS10790	COG0586	Pfam SNARE associated Golgi protein
KPL75_RS10800	COG0577	efflux transmembrane transporter activity
KPL75_RS10805	COG1136	(ABC) transporter
KPL75_RS10810	COG3708	Transcriptional regulator
KPL75_RS10810	COG2207	Transcriptional regulator
KPL75_RS10820	COG1131	(ABC) transporter
KPL75_RS10830	COG5658	integral membrane protein
KPL75_RS10835	COG0640	Transcriptional regulator
KPL75_RS10840	COG0745	RESPONSE REGULATOR receiver
KPL75_RS10845	COG2205	protein histidine kinase activity
KPL75_RS10850	COG0577	efflux transmembrane transporter activity
KPL75_RS10855	COG0577	efflux transmembrane transporter activity
KPL75_RS10860	COG1136	(ABC) transporter
KPL75_RS10865	COG0577	efflux transmembrane transporter activity
KPL75_RS10880	COG2188	Transcriptional regulator
KPL75_RS10900	COG3964	amidohydrolase
KPL75_RS10915	COG0745	RESPONSE REGULATOR receiver
KPL75_RS10920	COG4948	Mandelate Racemase Muconate Lactonizing
KPL75_RS10930	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KPL75_RS10935	COG0596	Alpha beta hydrolase
KPL75_RS10940	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KPL75_RS10945	COG1169	isochorismate synthase
KPL75_RS10950	COG1575	Belongs to the MenA family. Type 1 subfamily
KPL75_RS10955	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KPL75_RS10960	COG1278	Cold shock
KPL75_RS10985	COG0058	SHG alpha-glucan phosphorylase activity
KPL75_RS10995	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KPL75_RS11000	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KPL75_RS11005	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KPL75_RS11020	COG1309	transcriptional regulator
KPL75_RS11160	COG1285	pathogenesis
KPL75_RS11165	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KPL75_RS11175	COG0166	Belongs to the GPI family
KPL75_RS11180	COG2155	Conserved Protein
KPL75_RS11185	COG1098	S1 RNA binding domain
KPL75_RS11190	COG0436	Aminotransferase
KPL75_RS11195	COG1522	sequence-specific DNA binding
KPL75_RS11200	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KPL75_RS11205	COG2267	carboxylic ester hydrolase activity
KPL75_RS11215	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KPL75_RS11235	COG5018	Exonuclease
KPL75_RS11240	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KPL75_RS11260	COG2050	protein possibly involved in aromatic compounds catabolism
KPL75_RS11270	COG1268	BioY protein
KPL75_RS11280	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KPL75_RS11285	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KPL75_RS11295	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KPL75_RS11300	COG3584	3D domain protein
KPL75_RS11325	COG1252	NADH dehydrogenase
KPL75_RS11330	COG0492	ferredoxin-NADP+ reductase activity
KPL75_RS11335	COG3708	Transcriptional regulator
KPL75_RS11350	COG1683	Conserved Protein
KPL75_RS11360	COG0316	Belongs to the HesB IscA family
KPL75_RS11365	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KPL75_RS11370	COG4844	belongs to the
KPL75_RS11375	COG1252	NADH dehydrogenase
KPL75_RS11385	COG2274	protein secretion by the type I secretion system
KPL75_RS11390	COG0390	transport system, permease component
KPL75_RS11395	COG2824	Alkylphosphonate utilization operon protein PhnA
KPL75_RS11445	COG4837	Protein of unknown function (DUF1462)
KPL75_RS11450	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KPL75_RS11460	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KPL75_RS11465	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KPL75_RS11485	COG1358	cellular component organization or biogenesis
KPL75_RS11500	COG0647	UMP catabolic process
KPL75_RS11510	COG2445	Protein of unknown function DUF86
KPL75_RS11515	COG1494	fructose-1,6-bisphosphatase
KPL75_RS11535	COG4470	Protein conserved in bacteria
KPL75_RS11545	COG0789	Transcriptional regulator
KPL75_RS11550	COG4377	Putative membrane peptidase family (DUF2324)
KPL75_RS11575	COG0739	heme binding
KPL75_RS11585	COG3377	Domain of unknown function (DUF1805)
KPL75_RS11590	COG0737	Belongs to the 5'-nucleotidase family
KPL75_RS11595	COG0719	Fe-S assembly protein
KPL75_RS11600	COG0822	iron-sulfur transferase activity
KPL75_RS11605	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KPL75_RS11610	COG0719	Fe-S assembly protein
KPL75_RS11615	COG0396	ATPase activity
KPL75_RS11620	COG1464	Belongs to the NlpA lipoprotein family
KPL75_RS11625	COG1464	Belongs to the NlpA lipoprotein family
KPL75_RS11630	COG2011	ABC-type metal ion transport system permease component
KPL75_RS11645	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KPL75_RS11650	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KPL75_RS11655	COG0509	glycine decarboxylation via glycine cleavage system
KPL75_RS11660	COG1393	Belongs to the ArsC family
KPL75_RS11705	COG1309	transcriptional regulator
KPL75_RS11710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KPL75_RS11715	COG1960	acyl-CoA dehydrogenase activity
KPL75_RS11720	COG0183	Belongs to the thiolase family
KPL75_RS11725	COG1250	3-hydroxyacyl-CoA dehydrogenase
KPL75_RS11725	COG1024	Enoyl-CoA hydratase
KPL75_RS11735	COG1686	Belongs to the peptidase S11 family
KPL75_RS11740	COG0506	proline dehydrogenase activity
KPL75_RS11750	COG0011	TIGRFAM Protein of
KPL75_RS11755	COG0840	transmembrane signaling receptor activity
KPL75_RS11775	COG2801	Transposase and inactivated derivatives
KPL75_RS11780	COG2814	Major facilitator Superfamily
KPL75_RS11785	COG0531	amino acid
KPL75_RS11805	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KPL75_RS11815	COG5002	protein histidine kinase activity
KPL75_RS11820	COG0745	RESPONSE REGULATOR receiver
KPL75_RS11835	COG1131	(ABC) transporter
KPL75_RS11860	COG0586	Pfam SNARE associated Golgi protein
KPL75_RS11870	COG1376	ErfK ybiS ycfS ynhG family protein
KPL75_RS11875	COG0745	RESPONSE REGULATOR receiver
KPL75_RS11880	COG5002	protein histidine kinase activity
KPL75_RS11895	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KPL75_RS11905	COG0840	transmembrane signaling receptor activity
KPL75_RS11915	COG2151	metal-sulfur cluster biosynthetic enzyme
KPL75_RS11920	COG3227	Zinc metalloprotease (Elastase)
KPL75_RS11940	COG0586	Pfam SNARE associated Golgi protein
KPL75_RS11945	COG0475	glutathione-regulated potassium exporter activity
KPL75_RS11950	COG0490	domain, Protein
KPL75_RS11955	COG1115	amino acid carrier protein
KPL75_RS11960	COG0783	Belongs to the Dps family
KPL75_RS11980	COG1611	Belongs to the LOG family
KPL75_RS11990	COG1528	Iron-storage protein
KPL75_RS12000	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KPL75_RS12005	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KPL75_RS12010	COG1115	amino acid carrier protein
KPL75_RS12015	COG1115	amino acid carrier protein
KPL75_RS12020	COG2910	NAD(P)H-binding
KPL75_RS12040	COG0656	L-ascorbic acid biosynthetic process
KPL75_RS12045	COG2814	Major facilitator Superfamily
KPL75_RS12050	COG1733	regulation of RNA biosynthetic process
KPL75_RS12060	COG1252	NADH dehydrogenase
KPL75_RS12065	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KPL75_RS12080	COG0840	transmembrane signaling receptor activity
KPL75_RS12080	COG3290	protein histidine kinase activity
KPL75_RS12120	COG0488	(ABC) transporter
KPL75_RS12125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KPL75_RS12150	COG1522	sequence-specific DNA binding
KPL75_RS12155	COG0288	reversible hydration of carbon dioxide
KPL75_RS12160	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
KPL75_RS12165	COG2233	PERMEase
KPL75_RS12215	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KPL75_RS12220	COG0557	exoribonuclease II activity
KPL75_RS12225	COG1647	Serine aminopeptidase, S33
KPL75_RS12230	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KPL75_RS12235	COG1346	cytolysis
KPL75_RS12250	COG0148	phosphopyruvate hydratase activity
KPL75_RS12265	COG0126	phosphoglycerate kinase activity
KPL75_RS12270	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KPL75_RS12285	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KPL75_RS12315	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KPL75_RS12330	COG2323	membrane
KPL75_RS12340	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KPL75_RS12345	COG1481	regulation of sporulation
KPL75_RS12350	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KPL75_RS12355	COG1660	Displays ATPase and GTPase activities
KPL75_RS12360	COG1051	belongs to the nudix hydrolase family
KPL75_RS12370	COG0492	ferredoxin-NADP+ reductase activity
KPL75_RS12375	COG0457	Tetratricopeptide repeat
KPL75_RS12380	COG0110	maltose O-acetyltransferase activity
KPL75_RS12385	COG0546	phosphoglycolate phosphatase activity
KPL75_RS12390	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KPL75_RS12395	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KPL75_RS12400	COG1950	PFAM Membrane protein of
KPL75_RS12405	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KPL75_RS12425	COG0789	Transcriptional regulator
KPL75_RS12455	COG0583	DNA-binding transcription factor activity
KPL75_RS12465	COG0655	NAD(P)H dehydrogenase (quinone) activity
KPL75_RS12470	COG0488	(ABC) transporter
KPL75_RS12480	COG1132	(ABC) transporter
KPL75_RS12485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KPL75_RS12490	COG0793	Belongs to the peptidase S41A family
KPL75_RS12490	COG3409	Peptidoglycan-binding domain 1 protein
KPL75_RS12495	COG2177	Part of the ABC transporter FtsEX involved in
KPL75_RS12500	COG2884	Cell division ATP-binding protein ftsE
KPL75_RS12525	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KPL75_RS12530	COG1278	Cold shock
KPL75_RS12535	COG1040	competence protein
KPL75_RS12540	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KPL75_RS12545	COG0791	NLP P60 protein
KPL75_RS12545	COG1388	LysM domain
KPL75_RS12550	COG1733	regulation of RNA biosynthetic process
KPL75_RS12555	COG1307	EDD domain protein, DegV family
KPL75_RS12560	COG1739	Uncharacterized protein family UPF0029
KPL75_RS12565	COG1316	TRANSCRIPTIONal
KPL75_RS12570	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KPL75_RS12575	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KPL75_RS12580	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KPL75_RS12590	COG3933	PFAM sigma-54 factor interaction domain-containing protein
KPL75_RS12590	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KPL75_RS12610	COG1486	melibiose metabolic process
KPL75_RS12615	COG1447	Phosphotransferase system cellobiose-specific component IIA
KPL75_RS12620	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KPL75_RS12630	COG1447	Phosphotransferase system cellobiose-specific component IIA
KPL75_RS12640	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KPL75_RS12645	COG1301	dicarboxylic acid transport
KPL75_RS12660	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KPL75_RS12670	COG1271	oxidase subunit
KPL75_RS12675	COG1294	oxidase, subunit
KPL75_RS12680	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KPL75_RS12685	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KPL75_RS12690	COG1620	l-lactate permease
KPL75_RS12700	COG2389	metal-binding protein
KPL75_RS12710	COG1368	sulfuric ester hydrolase activity
KPL75_RS12720	COG1388	LysM domain
KPL75_RS12720	COG0791	NLP P60 protein
KPL75_RS12725	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KPL75_RS12735	COG1215	transferase activity, transferring glycosyl groups
KPL75_RS12740	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KPL75_RS12745	COG3584	3D domain protein
KPL75_RS12745	COG1388	LysM domain
KPL75_RS12755	COG4715	Zinc finger, swim domain protein
KPL75_RS12760	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KPL75_RS12800	COG0577	efflux transmembrane transporter activity
KPL75_RS12805	COG1136	(ABC) transporter
KPL75_RS12840	COG5002	protein histidine kinase activity
KPL75_RS12840	COG3850	Histidine kinase
KPL75_RS12845	COG0745	RESPONSE REGULATOR receiver
KPL75_RS12850	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KPL75_RS12865	COG1091	dTDP-4-dehydrorhamnose reductase activity
KPL75_RS12880	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KPL75_RS12895	COG0110	maltose O-acetyltransferase activity
KPL75_RS12945	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KPL75_RS12950	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KPL75_RS12955	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KPL75_RS12960	COG4464	protein tyrosine phosphatase activity
KPL75_RS12965	COG0489	protein tyrosine kinase activity
KPL75_RS12970	COG3944	biosynthesis protein
KPL75_RS12975	COG0489	protein tyrosine kinase activity
KPL75_RS12990	COG1609	Transcriptional regulator
KPL75_RS13000	COG0739	heme binding
KPL75_RS13015	COG4555	ABC transporter
KPL75_RS13020	COG2385	sporulation resulting in formation of a cellular spore
KPL75_RS13035	COG4836	Membrane
KPL75_RS13040	COG1007	ATP synthesis coupled electron transport
KPL75_RS13045	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KPL75_RS13050	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KPL75_RS13055	COG0713	ATP synthesis coupled electron transport
KPL75_RS13060	COG0839	Belongs to the complex I subunit 6 family
KPL75_RS13070	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
KPL75_RS13075	COG0649	NAD binding
KPL75_RS13080	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KPL75_RS13085	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KPL75_RS13090	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KPL75_RS13095	COG3300	MHYT domain
KPL75_RS13095	COG5001	Diguanylate cyclase
KPL75_RS13110	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KPL75_RS13115	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KPL75_RS13120	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KPL75_RS13125	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KPL75_RS13130	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KPL75_RS13135	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KPL75_RS13145	COG0356	it plays a direct role in the translocation of protons across the membrane
KPL75_RS13170	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KPL75_RS13180	COG0698	ribose 5-phosphate isomerase
KPL75_RS13190	COG2190	(PTS) system
KPL75_RS13195	COG2259	Doxx family
KPL75_RS13200	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KPL75_RS13210	COG1971	Probably functions as a manganese efflux pump
KPL75_RS13215	COG0009	L-threonylcarbamoyladenylate synthase
KPL75_RS13230	COG2890	protein-(glutamine-N5) methyltransferase activity
KPL75_RS13235	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KPL75_RS13240	COG1435	thymidine kinase activity
KPL75_RS13250	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KPL75_RS13255	COG1494	fructose-1,6-bisphosphatase
KPL75_RS13275	COG4821	SIS domain
KPL75_RS13280	COG0504	CTP synthase activity
KPL75_RS13295	COG1960	acyl-CoA dehydrogenase activity
KPL75_RS13300	COG1960	acyl-CoA dehydrogenase activity
KPL75_RS13305	COG1250	3-hydroxyacyl-CoA dehydrogenase
KPL75_RS13310	COG0183	Belongs to the thiolase family
KPL75_RS13315	COG2181	nitrate reductase activity
KPL75_RS13315	COG0247	lactate metabolic process
KPL75_RS13320	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KPL75_RS13325	COG4294	response to UV
KPL75_RS13330	COG5001	Diguanylate cyclase
KPL75_RS13330	COG3300	MHYT domain
KPL75_RS13345	COG3227	Zinc metalloprotease (Elastase)
KPL75_RS13350	COG2197	response regulator
KPL75_RS13355	COG4585	Histidine kinase
KPL75_RS13360	COG0842	Transport permease protein
KPL75_RS13365	COG1131	(ABC) transporter
KPL75_RS13370	COG0024	Methionine aminopeptidase
KPL75_RS13380	COG2234	aminopeptidase activity
KPL75_RS13395	COG4506	Protein conserved in bacteria
KPL75_RS13400	COG1619	proteins homologs of microcin C7 resistance protein MccF
KPL75_RS13425	COG2814	Major facilitator Superfamily
KPL75_RS13430	COG0789	Transcriptional regulator
KPL75_RS13435	COG0584	glycerophosphoryl diester phosphodiesterase
KPL75_RS13440	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KPL75_RS13450	COG1994	Peptidase M50
KPL75_RS13460	COG1078	dGTPase activity
KPL75_RS13465	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KPL75_RS13470	COG1120	ATPase activity
KPL75_RS13475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KPL75_RS13480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KPL75_RS13485	COG4844	belongs to the
KPL75_RS13500	COG0280	phosphate acetyltransferase
KPL75_RS13505	COG3253	May function as heme-dependent peroxidase
KPL75_RS13515	COG3773	Cell wall hydrolase
KPL75_RS13525	COG2363	Small membrane protein
KPL75_RS13535	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KPL75_RS13540	COG2233	PERMEase
KPL75_RS13545	COG0561	phosphatase activity
KPL75_RS13550	COG2814	Major facilitator Superfamily
KPL75_RS13555	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KPL75_RS13560	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KPL75_RS13565	COG1131	(ABC) transporter
KPL75_RS13570	COG2755	lipolytic protein G-D-S-L family
KPL75_RS13575	COG1609	Transcriptional regulator
KPL75_RS13585	COG0460	homoserine dehydrogenase
KPL75_RS13590	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KPL75_RS13595	COG2873	o-acetylhomoserine
KPL75_RS13605	COG1011	Hydrolase
KPL75_RS13610	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KPL75_RS13620	COG2197	response regulator
KPL75_RS13625	COG4585	Histidine kinase
KPL75_RS13625	COG2203	Gaf domain
KPL75_RS13630	COG0351	phosphomethylpyrimidine kinase
KPL75_RS13635	COG3706	GGDEF domain
KPL75_RS13640	COG2879	small protein
KPL75_RS13645	COG1966	Carbon starvation protein
KPL75_RS13650	COG3279	Response regulator of the LytR AlgR family
KPL75_RS13655	COG0477	Major facilitator Superfamily
KPL75_RS13680	COG0840	transmembrane signaling receptor activity
KPL75_RS13690	COG1607	acyl-coa hydrolase
KPL75_RS13695	COG1216	Glycosyl transferase, family 2
KPL75_RS13705	COG1216	Glycosyl transferase, family 2
KPL75_RS13720	COG0488	(ABC) transporter
KPL75_RS13735	COG0463	Glycosyl transferase, family 2
KPL75_RS13740	COG1309	transcriptional regulator
KPL75_RS13745	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KPL75_RS13750	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KPL75_RS13750	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KPL75_RS13755	COG0628	permease
KPL75_RS13765	COG1380	Effector of murein hydrolase LrgA
KPL75_RS13770	COG3279	Response regulator of the LytR AlgR family
KPL75_RS13775	COG3275	phosphorelay sensor kinase activity
KPL75_RS13785	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KPL75_RS13790	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KPL75_RS13825	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KPL75_RS13830	COG1272	protein, Hemolysin III
KPL75_RS13855	COG1164	Oligoendopeptidase f
KPL75_RS13870	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KPL75_RS13880	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KPL75_RS13885	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KPL75_RS13890	COG4853	Protein conserved in bacteria
KPL75_RS13900	COG5002	protein histidine kinase activity
KPL75_RS13905	COG0745	RESPONSE REGULATOR receiver
KPL75_RS13935	COG0305	Participates in initiation and elongation during chromosome replication
KPL75_RS13945	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KPL75_RS13950	COG4241	membrane
KPL75_RS13960	COG0629	single-stranded DNA binding
KPL75_RS13965	COG0360	Binds together with S18 to 16S ribosomal RNA
KPL75_RS13970	COG0012	GTP binding
KPL75_RS13975	COG4481	Protein conserved in bacteria
KPL75_RS13980	COG0668	transmembrane transport
KPL75_RS13990	COG1475	DNA binding
KPL75_RS13995	COG1192	Involved in chromosome partitioning
KPL75_RS14000	COG1475	DNA binding
KPL75_RS14005	COG0357	Ribosomal RNA small subunit methyltransferase G
KPL75_RS14010	COG0445	tRNA wobble uridine modification
KPL75_RS14015	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KPL75_RS14020	COG1847	R3H domain protein
KPL75_RS14025	COG0706	membrane insertase activity
KPL75_RS14030	COG0594	ribonuclease P activity
KPL75_RS14035	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KPL75_RS14040	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KPL75_RS14045	COG0592	DNA-directed DNA polymerase activity
KPL75_RS14050	COG2501	S4 domain
KPL75_RS14055	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KPL75_RS14060	COG0187	DNA topoisomerase II activity
KPL75_RS14065	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KPL75_RS14100	COG0516	GMP reductase activity
KPL75_RS14100	COG0517	IMP dehydrogenase activity
KPL75_RS14105	COG1686	Belongs to the peptidase S11 family
KPL75_RS14115	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KPL75_RS14135	COG1428	Deoxynucleoside kinase
KPL75_RS14140	COG1428	Deoxynucleoside kinase
KPL75_RS14145	COG1335	isochorismatase
KPL75_RS14150	COG0590	tRNA wobble adenosine to inosine editing
KPL75_RS14160	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KPL75_RS14170	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KPL75_RS14215	COG1982	Orn Lys Arg decarboxylase major
KPL75_RS14220	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KPL75_RS14225	COG0470	DNA polymerase III
KPL75_RS14230	COG1774	PSP1 C-terminal conserved region
KPL75_RS14235	COG4467	Involved in initiation control of chromosome replication
KPL75_RS14240	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KPL75_RS14250	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KPL75_RS14255	COG2002	toxin-antitoxin pair type II binding
KPL75_RS14265	COG0084	hydrolase, TatD family'
KPL75_RS14270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KPL75_RS14275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KPL75_RS14285	COG4466	Protein conserved in bacteria
KPL75_RS14300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KPL75_RS14305	COG0251	oxidation-reduction process
KPL75_RS14310	COG2088	sporulation resulting in formation of a cellular spore
KPL75_RS14315	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KPL75_RS14335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KPL75_RS14340	COG2002	toxin-antitoxin pair type II binding
KPL75_RS14345	COG2244	polysaccharide biosynthetic process
KPL75_RS14350	COG3956	TIGRFAM MazG family protein
KPL75_RS14355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KPL75_RS14375	COG1098	S1 RNA binding domain
KPL75_RS14390	COG2208	phosphoserine phosphatase activity
KPL75_RS14400	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KPL75_RS14405	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KPL75_RS14415	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KPL75_RS14420	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KPL75_RS14425	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KPL75_RS14430	COG0512	Glutamine amidotransferase of anthranilate synthase
KPL75_RS14435	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KPL75_RS14440	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KPL75_RS14445	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KPL75_RS14450	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KPL75_RS14455	COG1396	sequence-specific DNA binding
KPL75_RS14460	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KPL75_RS14550	COG3880	PFAM UvrB UvrC protein
KPL75_RS14555	COG3869	Catalyzes the specific phosphorylation of arginine residues in
KPL75_RS14560	COG0542	response to heat
KPL75_RS14565	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KPL75_RS14570	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
KPL75_RS14575	COG4956	integral membrane protein (PIN domain superfamily)
KPL75_RS14580	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KPL75_RS14590	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KPL75_RS14595	COG1045	serine acetyltransferase
KPL75_RS14600	COG0215	cysteine-tRNA ligase activity
KPL75_RS14610	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KPL75_RS14615	COG3688	RNA-binding protein containing a PIN domain
KPL75_RS14625	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KPL75_RS14630	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KPL75_RS14635	COG0250	Participates in transcription elongation, termination and antitermination
KPL75_RS14640	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KPL75_RS14645	COG0081	regulation of translation
KPL75_RS14650	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KPL75_RS14655	COG0222	ribosome binding
KPL75_RS14660	COG2813	Specifically methylates the guanine in position
KPL75_RS14665	COG0085	RNA polymerase activity
KPL75_RS14670	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KPL75_RS14675	COG1358	cellular component organization or biogenesis
KPL75_RS14680	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KPL75_RS14690	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KPL75_RS14695	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KPL75_RS14700	COG0051	transcription antitermination factor activity, RNA binding
KPL75_RS14705	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KPL75_RS14710	COG0088	Forms part of the polypeptide exit tunnel
KPL75_RS14715	COG0089	rRNA binding
KPL75_RS14720	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KPL75_RS14745	COG0255	Belongs to the universal ribosomal protein uL29 family
KPL75_RS14750	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KPL75_RS14760	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KPL75_RS14765	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KPL75_RS14775	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KPL75_RS14785	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KPL75_RS14795	COG1841	ribosomal large subunit assembly
KPL75_RS14800	COG0200	Binds to the 23S rRNA
KPL75_RS14805	COG0201	protein transport
KPL75_RS14810	COG0563	adenylate kinase activity
KPL75_RS14815	COG0024	Methionine aminopeptidase
KPL75_RS14825	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KPL75_RS14830	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KPL75_RS14835	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KPL75_RS14860	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KPL75_RS14870	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KPL75_RS14885	COG0860	N-Acetylmuramoyl-L-alanine amidase
KPL75_RS14890	COG0489	protein tyrosine kinase activity
KPL75_RS14900	COG2194	sulfuric ester hydrolase activity
KPL75_RS14905	COG0726	polysaccharide deacetylase
KPL75_RS14985	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KPL75_RS14990	COG4856	YbbR-like protein
KPL75_RS15010	COG4946	Tricorn protease homolog
KPL75_RS15010	COG1506	peptidase
KPL75_RS15010	COG0823	Involved in the tonB-independent uptake of proteins
KPL75_RS15045	COG1028	Short-chain dehydrogenase reductase Sdr
KPL75_RS15050	COG2011	ABC-type metal ion transport system permease component
KPL75_RS15060	COG1464	Belongs to the NlpA lipoprotein family
KPL75_RS15065	COG0604	alcohol dehydrogenase
KPL75_RS15070	COG0277	FAD linked oxidase domain protein
KPL75_RS15075	COG2271	Major facilitator Superfamily
KPL75_RS15085	COG2814	Major facilitator Superfamily
KPL75_RS15105	COG0601	transmembrane transport
KPL75_RS15110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KPL75_RS15115	COG0444	Belongs to the ABC transporter superfamily
KPL75_RS15120	COG4608	Belongs to the ABC transporter superfamily
KPL75_RS15125	COG4166	transmembrane transport
KPL75_RS15135	COG1309	transcriptional regulator
KPL75_RS15145	COG4166	transmembrane transport
KPL75_RS15150	COG4166	transmembrane transport
KPL75_RS15155	COG0656	L-ascorbic acid biosynthetic process
KPL75_RS15175	COG4149	molybdate abc transporter
KPL75_RS15180	COG0725	ABC transporter, periplasmic molybdate-binding protein
KPL75_RS15185	COG1910	domain protein
KPL75_RS15200	COG0697	spore germination
KPL75_RS15215	COG0204	Acyl-transferase
KPL75_RS15225	COG1609	Transcriptional regulator
KPL75_RS15235	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KPL75_RS15250	COG5298	Protein conserved in bacteria
KPL75_RS15275	COG0488	(ABC) transporter
KPL75_RS15280	COG4585	Histidine kinase
KPL75_RS15285	COG2197	response regulator
KPL75_RS15290	COG1131	(ABC) transporter
KPL75_RS15295	COG0842	Transport permease protein
KPL75_RS15295	COG1511	domain protein
KPL75_RS15300	COG0842	Transport permease protein
KPL75_RS15310	COG0747	negative chemotaxis
KPL75_RS15315	COG0747	negative chemotaxis
KPL75_RS15320	COG0601	transmembrane transport
KPL75_RS15325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KPL75_RS15330	COG0444	Belongs to the ABC transporter superfamily
KPL75_RS15335	COG4608	Belongs to the ABC transporter superfamily
KPL75_RS15340	COG0561	phosphatase activity
KPL75_RS15380	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KPL75_RS15385	COG0179	Fumarylacetoacetate (FAA) hydrolase
KPL75_RS15395	COG0531	amino acid
KPL75_RS15400	COG2814	Major facilitator Superfamily
KPL75_RS15410	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KPL75_RS15420	COG4294	response to UV
KPL75_RS15425	COG0705	Rhomboid family
KPL75_RS15430	COG0736	holo-[acyl-carrier-protein] synthase activity
KPL75_RS15435	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KPL75_RS15440	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KPL75_RS15445	COG0864	Transcriptional regulator
KPL75_RS15450	COG2337	Toxic component of a toxin-antitoxin (TA) module
KPL75_RS15455	COG2183	response to ionizing radiation
KPL75_RS15555	COG0802	atpase or kinase
KPL75_RS15560	COG1214	PFAM Peptidase M22, glycoprotease
KPL75_RS15565	COG0456	acetyltransferase
KPL75_RS15575	COG0488	(ABC) transporter
KPL75_RS15580	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KPL75_RS15590	COG1266	CAAX protease self-immunity
KPL75_RS15595	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KPL75_RS15600	COG0459	protein refolding
KPL75_RS15605	COG0519	Catalyzes the synthesis of GMP from XMP
KPL75_RS15605	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KPL75_RS15610	COG2252	PERMEase
KPL75_RS15620	COG5002	protein histidine kinase activity
KPL75_RS15645	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KPL75_RS15680	COG2226	methyltransferase
KPL75_RS15690	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KPL75_RS15700	COG1215	transferase activity, transferring glycosyl groups
KPL75_RS15760	COG0697	spore germination
KPL75_RS15785	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KPL75_RS15790	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KPL75_RS15795	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KPL75_RS15805	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KPL75_RS15810	COG0047	phosphoribosylformylglycinamidine synthase activity
KPL75_RS15820	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KPL75_RS15830	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KPL75_RS15835	COG0138	bifunctional purine biosynthesis protein purh
KPL75_RS15840	COG0151	Belongs to the GarS family
KPL75_RS15860	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
KPL75_RS15865	COG0210	DNA helicase
KPL75_RS15870	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KPL75_RS15875	COG4851	CamS sex pheromone cAM373 precursor
KPL75_RS15885	COG1012	belongs to the aldehyde dehydrogenase family
KPL75_RS15890	COG1335	isochorismatase
KPL75_RS15900	COG2011	ABC-type metal ion transport system permease component
KPL75_RS15905	COG1464	Belongs to the NlpA lipoprotein family
KPL75_RS15920	COG0003	Pfam Anion-transporting ATPase
KPL75_RS15925	COG1846	Transcriptional regulator
KPL75_RS15930	COG4682	membrane
KPL75_RS15945	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KPL75_RS15950	COG1597	lipid kinase activity
KPL75_RS15960	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KPL75_RS15970	COG1012	belongs to the aldehyde dehydrogenase family
KPL75_RS15975	COG2076	Multidrug Resistance protein
KPL75_RS15980	COG2309	aminopeptidase activity
KPL75_RS15995	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KPL75_RS16005	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KPL75_RS16010	COG5002	protein histidine kinase activity
KPL75_RS16020	COG4807	Protein conserved in bacteria
KPL75_RS16045	COG1757	Na H antiporter
KPL75_RS16050	COG1473	amidohydrolase
KPL75_RS16065	COG0450	alkyl hydroperoxide reductase
KPL75_RS16075	COG3279	Response regulator of the LytR AlgR family
KPL75_RS16080	COG2972	Histidine kinase
KPL75_RS16080	COG0745	RESPONSE REGULATOR receiver
KPL75_RS16090	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KPL75_RS16100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KPL75_RS16105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KPL75_RS16110	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KPL75_RS16115	COG0492	ferredoxin-NADP+ reductase activity
KPL75_RS16125	COG0166	Belongs to the GPI family
KPL75_RS16150	COG5002	protein histidine kinase activity
KPL75_RS16170	COG3541	Predicted nucleotidyltransferase
KPL75_RS16175	COG2814	Major facilitator Superfamily
KPL75_RS16180	COG0723	plastoquinol--plastocyanin reductase activity
KPL75_RS16180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KPL75_RS16190	COG0765	amino acid transport
KPL75_RS16195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KPL75_RS16205	COG0840	transmembrane signaling receptor activity
KPL75_RS16210	COG0277	FAD linked oxidase domain protein
KPL75_RS16215	COG0366	Alpha amylase catalytic
KPL75_RS16220	COG1263	PTS System
KPL75_RS16220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KPL75_RS16220	COG2190	(PTS) system
KPL75_RS16240	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KPL75_RS16245	COG0352	thiamine-phosphate diphosphorylase activity
KPL75_RS16250	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KPL75_RS16265	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KPL75_RS16270	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KPL75_RS16275	COG1116	anion transmembrane transporter activity
KPL75_RS16285	COG0488	(ABC) transporter
KPL75_RS16325	COG2270	Major facilitator Superfamily
KPL75_RS16355	COG2310	stress, protein
KPL75_RS16360	COG2310	stress, protein
KPL75_RS16365	COG2310	stress, protein
KPL75_RS16370	COG0861	Integral membrane protein TerC family
KPL75_RS16380	COG3853	Toxic anion resistance protein (TelA)
KPL75_RS16390	COG4840	Belongs to the UPF0435 family
KPL75_RS16395	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KPL75_RS16405	COG1295	ribonuclease BN
KPL75_RS16410	COG2217	Heavy metal translocating P-type atpase
KPL75_RS16415	COG0697	spore germination
KPL75_RS16435	COG0586	Pfam SNARE associated Golgi protein
KPL75_RS16450	COG3871	stress protein (general stress protein 26)
KPL75_RS16455	COG0387	Pfam Sodium calcium exchanger
KPL75_RS16465	COG0535	radical SAM domain protein
KPL75_RS16485	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KPL75_RS16505	COG3829	transcription factor binding
KPL75_RS16515	COG0833	amino acid
KPL75_RS16545	COG1263	PTS System
KPL75_RS16545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KPL75_RS16550	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KPL75_RS16565	COG1216	Glycosyl transferase, family 2
KPL75_RS16575	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KPL75_RS16575	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KPL75_RS16580	COG0463	Glycosyl transferase, family 2
KPL75_RS16595	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KPL75_RS16600	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KPL75_RS16615	COG1228	amidohydrolase
KPL75_RS16620	COG1090	epimerase
KPL75_RS16625	COG2137	regulation of response to DNA damage stimulus
KPL75_RS16650	COG1988	membrane-bound metal-dependent
KPL75_RS16655	COG1194	a g-specific adenine glycosylase
KPL75_RS16675	COG3557	Belongs to the UPF0374 family
KPL75_RS16680	COG1132	(ABC) transporter
KPL75_RS16685	COG4129	membrane
KPL75_RS16690	COG0067	glutamate synthase
KPL75_RS16690	COG0069	glutamate synthase activity
KPL75_RS16690	COG0070	glutamate synthase
KPL75_RS16695	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KPL75_RS16700	COG4555	ABC transporter
KPL75_RS16720	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KPL75_RS16725	COG0735	belongs to the Fur family
KPL75_RS16840	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KPL75_RS16845	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KPL75_RS16865	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KPL75_RS16875	COG2766	serine protein kinase
KPL75_RS16880	COG2718	Belongs to the UPF0229 family
KPL75_RS16895	COG1585	Membrane protein implicated in regulation of membrane protease activity
KPL75_RS16900	COG2268	Band 7 protein
KPL75_RS16910	COG3290	protein histidine kinase activity
KPL75_RS16915	COG4565	transcriptional regulatory protein
KPL75_RS16920	COG2851	Citrate transporter
KPL75_RS16945	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KPL75_RS16950	COG3842	ATPase activity
KPL75_RS16955	COG1175	transmembrane transport
KPL75_RS16960	COG0395	ABC-type sugar transport system, permease component
KPL75_RS16970	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KPL75_RS16975	COG0745	RESPONSE REGULATOR receiver
KPL75_RS16980	COG5002	protein histidine kinase activity
KPL75_RS16990	COG4990	cell redox homeostasis
KPL75_RS17000	COG3290	protein histidine kinase activity
KPL75_RS17005	COG4565	transcriptional regulatory protein
KPL75_RS17010	COG3493	citrate carrier protein
KPL75_RS17015	COG0281	malic enzyme
KPL75_RS17025	COG0697	spore germination
KPL75_RS17030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KPL75_RS17040	COG5002	protein histidine kinase activity
KPL75_RS17045	COG0745	RESPONSE REGULATOR receiver
KPL75_RS17050	COG0456	acetyltransferase
KPL75_RS17055	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KPL75_RS17060	COG3383	formate dehydrogenase (NAD+) activity
KPL75_RS17065	COG2427	Protein of unknown function (DUF1641)
KPL75_RS17080	COG0531	amino acid
KPL75_RS17090	COG0640	Transcriptional regulator
KPL75_RS17095	COG2217	Heavy metal translocating P-type atpase
KPL75_RS17100	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KPL75_RS17115	COG3227	Zinc metalloprotease (Elastase)
KPL75_RS17135	COG2720	vancomycin resistance protein
KPL75_RS17140	COG1316	TRANSCRIPTIONal
KPL75_RS17145	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KPL75_RS17150	COG0346	lactoylglutathione lyase activity
KPL75_RS17155	COG1253	flavin adenine dinucleotide binding
KPL75_RS17160	COG1027	Aspartate ammonia-lyase
KPL75_RS17165	COG1620	l-lactate permease
KPL75_RS17180	COG3104	oligopeptide transport
KPL75_RS17185	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KPL75_RS17190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KPL75_RS17195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KPL75_RS17215	COG0156	8-amino-7-oxononanoate synthase activity
KPL75_RS17220	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KPL75_RS17225	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KPL75_RS17235	COG4548	von Willebrand factor, type A
KPL75_RS17240	COG0714	Associated with various cellular activities
KPL75_RS17245	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KPL75_RS17265	COG0531	amino acid
KPL75_RS17270	COG2188	Transcriptional regulator
KPL75_RS17275	COG1263	PTS System
KPL75_RS17275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KPL75_RS17280	COG0366	Alpha amylase catalytic
KPL75_RS17295	COG0697	spore germination
KPL75_RS17305	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KPL75_RS17310	COG1115	amino acid carrier protein
KPL75_RS17315	COG1126	abc transporter atp-binding protein
KPL75_RS17320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KPL75_RS17325	COG0765	amino acid transport
KPL75_RS17330	COG0765	amino acid transport
KPL75_RS17335	COG0833	amino acid
KPL75_RS17350	COG1595	DNA-templated transcription, initiation
KPL75_RS17360	COG2378	regulation of single-species biofilm formation
KPL75_RS17365	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KPL75_RS17370	COG5002	protein histidine kinase activity
KPL75_RS17390	COG2814	Major facilitator Superfamily
KPL75_RS17395	COG0659	secondary active sulfate transmembrane transporter activity
KPL75_RS17410	COG0747	negative chemotaxis
KPL75_RS17420	COG0601	transmembrane transport
KPL75_RS17425	COG4608	Belongs to the ABC transporter superfamily
KPL75_RS17435	COG2271	Major facilitator Superfamily
KPL75_RS17440	COG1846	Transcriptional regulator
KPL75_RS17445	COG0477	Major facilitator Superfamily
KPL75_RS17450	COG1609	Transcriptional regulator
KPL75_RS17455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KPL75_RS17460	COG1869	D-ribose catabolic process
KPL75_RS17470	COG1172	Belongs to the binding-protein-dependent transport system permease family
KPL75_RS17475	COG1879	ABC-type sugar transport system periplasmic component
KPL75_RS17505	COG1063	alcohol dehydrogenase
KPL75_RS17520	COG3568	Endonuclease Exonuclease Phosphatase
KPL75_RS17550	COG0840	transmembrane signaling receptor activity
KPL75_RS17555	COG1388	LysM domain
KPL75_RS17555	COG3584	3D domain protein
KPL75_RS17560	COG1476	TRANSCRIPTIONal
KPL75_RS17580	COG3104	oligopeptide transport
KPL75_RS17590	COG1114	Component of the transport system for branched-chain amino acids
KPL75_RS17605	COG1113	amino acid transport
KPL75_RS17610	COG2252	PERMEase
KPL75_RS17625	COG2153	protein acetylation
KPL75_RS17635	COG0475	glutathione-regulated potassium exporter activity
KPL75_RS17635	COG0569	domain protein
KPL75_RS17645	COG1845	cytochrome c oxidase, subunit III
KPL75_RS17650	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KPL75_RS17660	COG0833	amino acid
KPL75_RS17665	COG4990	cell redox homeostasis
KPL75_RS17685	COG0697	spore germination
KPL75_RS17690	COG0531	amino acid
KPL75_RS17705	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KPL75_RS17710	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KPL75_RS17715	COG1918	ferrous iron import across plasma membrane
KPL75_RS17715	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KPL75_RS17720	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KPL75_RS17725	COG0573	inorganic phosphate transmembrane transporter activity
KPL75_RS17730	COG0581	inorganic phosphate transmembrane transporter activity
KPL75_RS17740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KPL75_RS17860	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KPL75_RS17875	COG0860	N-Acetylmuramoyl-L-alanine amidase
KPL75_RS17875	COG3103	Sh3 type 3 domain protein
KPL75_RS17875	COG4991	sh3 domain protein
KPL75_RS17880	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KPL75_RS17885	COG1116	anion transmembrane transporter activity
KPL75_RS17890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KPL75_RS17895	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KPL75_RS17900	COG0352	thiamine-phosphate diphosphorylase activity
KPL75_RS17905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KPL75_RS17910	COG2104	thiamine diphosphate biosynthetic process
KPL75_RS17920	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KPL75_RS17925	COG0351	phosphomethylpyrimidine kinase
KPL75_RS17950	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KPL75_RS17955	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KPL75_RS17960	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
KPL75_RS17965	COG2205	protein histidine kinase activity
KPL75_RS17970	COG2814	Major facilitator Superfamily
KPL75_RS17975	COG1846	Transcriptional regulator
KPL75_RS17995	COG1172	Belongs to the binding-protein-dependent transport system permease family
KPL75_RS18000	COG1129	ABC transporter
KPL75_RS18010	COG2252	PERMEase
KPL75_RS18015	COG1028	Short-chain dehydrogenase reductase Sdr
KPL75_RS18020	COG1376	ErfK ybiS ycfS ynhG family protein
KPL75_RS18075	COG0778	Nitroreductase
KPL75_RS18080	COG2719	SpoVR family
KPL75_RS18110	COG1937	Protein conserved in bacteria
KPL75_RS18115	COG0425	Belongs to the sulfur carrier protein TusA family
KPL75_RS18115	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KPL75_RS18120	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KPL75_RS18120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KPL75_RS18125	COG0425	Belongs to the sulfur carrier protein TusA family
KPL75_RS18130	COG0425	Belongs to the sulfur carrier protein TusA family
KPL75_RS18130	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KPL75_RS18135	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KPL75_RS18140	COG2210	Belongs to the sulfur carrier protein TusA family
KPL75_RS18145	COG0730	response to heat
KPL75_RS18155	COG1316	TRANSCRIPTIONal
KPL75_RS18160	COG0604	alcohol dehydrogenase
KPL75_RS18165	COG1283	sodium-dependent phosphate transmembrane transporter activity
KPL75_RS18170	COG2814	Major facilitator Superfamily
KPL75_RS18180	COG3711	transcriptional antiterminator
KPL75_RS18180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KPL75_RS18185	COG1447	Phosphotransferase system cellobiose-specific component IIA
KPL75_RS18190	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KPL75_RS18210	COG3584	3D domain protein
KPL75_RS18210	COG1388	LysM domain
KPL75_RS18215	COG0577	efflux transmembrane transporter activity
KPL75_RS18220	COG1136	(ABC) transporter
KPL75_RS18230	COG5522	Integral membrane protein (intg_mem_TP0381)
KPL75_RS18245	COG0577	efflux transmembrane transporter activity
KPL75_RS18250	COG1114	Component of the transport system for branched-chain amino acids
KPL75_RS18255	COG3546	catalase activity
KPL75_RS18280	COG0586	Pfam SNARE associated Golgi protein
KPL75_RS18310	COG0531	amino acid
KPL75_RS18315	COG0475	glutathione-regulated potassium exporter activity
KPL75_RS18325	COG1737	Transcriptional regulator
KPL75_RS18335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KPL75_RS18335	COG1263	PTS System
KPL75_RS18345	COG2259	Doxx family
KPL75_RS18365	COG1522	sequence-specific DNA binding
KPL75_RS18390	COG2076	Multidrug Resistance protein
KPL75_RS18395	COG1309	transcriptional regulator
KPL75_RS18400	COG2814	Major facilitator Superfamily
KPL75_RS18405	COG1733	regulation of RNA biosynthetic process
KPL75_RS18415	COG2249	NAD(P)H dehydrogenase (quinone) activity
KPL75_RS18425	COG4533	DNA binding
KPL75_RS18430	COG2211	Major facilitator Superfamily
KPL75_RS18445	COG0531	amino acid
KPL75_RS18450	COG1012	belongs to the aldehyde dehydrogenase family
KPL75_RS18455	COG1132	(ABC) transporter
KPL75_RS18460	COG1132	(ABC) transporter
KPL75_RS18465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KPL75_RS18470	COG0765	amino acid transport
KPL75_RS18475	COG1126	abc transporter atp-binding protein
KPL75_RS18490	COG0189	ligase activity
KPL75_RS18500	COG4399	Belongs to the UPF0754 family
KPL75_RS18505	COG3679	Belongs to the UPF0342 family
KPL75_RS18520	COG0028	Belongs to the TPP enzyme family
KPL75_RS18525	COG3527	Alpha-acetolactate decarboxylase
KPL75_RS18530	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KPL75_RS18540	COG0561	phosphatase activity
KPL75_RS18550	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KPL75_RS18565	COG0586	Pfam SNARE associated Golgi protein
KPL75_RS18575	COG0789	Transcriptional regulator
KPL75_RS18575	COG4978	Transcriptional regulator
KPL75_RS18585	COG0659	secondary active sulfate transmembrane transporter activity
KPL75_RS18605	COG2244	polysaccharide biosynthetic process
KPL75_RS18620	COG1361	Conserved repeat domain
KPL75_RS18635	COG1024	Enoyl-CoA hydratase
KPL75_RS18650	COG1363	Peptidase, m42
KPL75_RS18685	COG0579	oxidoreductase
KPL75_RS18705	COG0601	transmembrane transport
KPL75_RS18710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KPL75_RS18715	COG0444	Belongs to the ABC transporter superfamily
KPL75_RS18720	COG4608	Belongs to the ABC transporter superfamily
KPL75_RS18820	COG0477	Major facilitator Superfamily
KPL75_RS18825	COG3290	protein histidine kinase activity
KPL75_RS18830	COG4565	transcriptional regulatory protein
KPL75_RS18835	COG3181	Tripartite tricarboxylate transporter family receptor
KPL75_RS18880	COG0789	Transcriptional regulator
KPL75_RS18880	COG4978	Transcriptional regulator
KPL75_RS18895	COG0305	Participates in initiation and elongation during chromosome replication
KPL75_RS18920	COG1842	Phage shock protein A
KPL75_RS18935	COG0477	Major facilitator Superfamily
KPL75_RS18975	COG2814	Major facilitator Superfamily
KPL75_RS18980	COG0640	Transcriptional regulator
KPL75_RS18985	COG3711	transcriptional antiterminator
KPL75_RS18990	COG1263	PTS System
KPL75_RS18990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KPL75_RS18990	COG2190	(PTS) system
KPL75_RS18995	COG2723	6-phospho-beta-galactosidase activity
KPL75_RS19010	COG2376	Dihydroxyacetone kinase
KPL75_RS19020	COG2376	Dihydroxyacetone kinase
KPL75_RS19040	COG1335	isochorismatase
KPL75_RS19090	COG2801	Transposase and inactivated derivatives
KPL75_RS19105	COG0076	glutamate decarboxylase activity
KPL75_RS19130	COG1388	LysM domain
KPL75_RS19150	COG2807	transmembrane transport
KPL75_RS19170	COG4585	Histidine kinase
KPL75_RS19175	COG2197	response regulator
KPL75_RS19205	COG0420	3'-5' exonuclease activity
KPL75_RS19210	COG4717	serine-type aminopeptidase activity
KPL75_RS19215	COG3481	metal-dependent phosphohydrolase, HD sub domain
KPL75_RS19225	COG0346	lactoylglutathione lyase activity
KPL75_RS19230	COG0346	lactoylglutathione lyase activity
KPL75_RS19245	COG2267	carboxylic ester hydrolase activity
KPL75_RS19255	COG2140	Oxalate decarboxylase
KPL75_RS19260	COG3620	sequence-specific DNA binding
KPL75_RS19265	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KPL75_RS19270	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KPL75_RS19275	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KPL75_RS19280	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KPL75_RS19295	COG1595	DNA-templated transcription, initiation
KPL75_RS19305	COG0772	Belongs to the SEDS family
KPL75_RS19315	COG3973	AAA domain
KPL75_RS19335	COG1846	Transcriptional regulator
KPL75_RS19345	COG0537	adenosine 5'-monophosphoramidase activity
KPL75_RS19350	COG1131	(ABC) transporter
KPL75_RS19355	COG4473	ABC transporter
KPL75_RS19365	COG0247	lactate metabolic process
KPL75_RS19370	COG1139	Iron-sulfur cluster binding protein
KPL75_RS19375	COG1556	Lactate utilization protein
KPL75_RS19395	COG3402	PFAM membrane-flanked domain
KPL75_RS19400	COG3428	Bacterial PH domain
KPL75_RS19440	COG1136	(ABC) transporter
KPL75_RS19445	COG0577	efflux transmembrane transporter activity
KPL75_RS19465	COG3402	PFAM membrane-flanked domain
KPL75_RS19470	COG3428	Bacterial PH domain
KPL75_RS19475	COG2329	Antibiotic biosynthesis monooxygenase
KPL75_RS19480	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KPL75_RS19495	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KPL75_RS19535	COG1309	transcriptional regulator
KPL75_RS19540	COG1511	domain protein
KPL75_RS19540	COG1511	domain protein
KPL75_RS19575	COG2378	regulation of single-species biofilm formation
KPL75_RS19580	COG1609	Transcriptional regulator
KPL75_RS19590	COG1234	tRNA 3'-trailer cleavage
KPL75_RS19595	COG0095	Lipoate-protein ligase
KPL75_RS19600	COG0318	PFAM AMP-dependent synthetase and ligase
KPL75_RS19610	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KPL75_RS19620	COG4208	sulfate ABC transporter
KPL75_RS19635	COG1408	metallophosphoesterase
KPL75_RS19640	COG1078	dGTPase activity
KPL75_RS19655	COG1595	DNA-templated transcription, initiation
KPL75_RS19660	COG3708	Transcriptional regulator
KPL75_RS19660	COG2207	Transcriptional regulator
KPL75_RS19665	COG2205	protein histidine kinase activity
KPL75_RS19670	COG0745	RESPONSE REGULATOR receiver
KPL75_RS19695	COG0501	Belongs to the peptidase M48B family
KPL75_RS19700	COG0697	spore germination
KPL75_RS19715	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KPL75_RS19720	COG2224	Isocitrate lyase
KPL75_RS19730	COG1278	Cold shock
KPL75_RS19740	COG4903	ComK protein
KPL75_RS19750	COG0398	Pfam SNARE associated Golgi protein
KPL75_RS19760	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KPL75_RS19820	COG0179	Fumarylacetoacetate (FAA) hydrolase
KPL75_RS19845	COG0367	asparagine synthase
KPL75_RS19860	COG0753	catalase activity
KPL75_RS19875	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KPL75_RS19895	COG3339	Conserved Protein
KPL75_RS19900	COG0004	ammonium transporteR
KPL75_RS19915	COG2996	Protein conserved in bacteria
KPL75_RS19930	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KPL75_RS19940	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KPL75_RS19955	COG0561	phosphatase activity
KPL75_RS19975	COG2267	carboxylic ester hydrolase activity
KPL75_RS19990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KPL75_RS19995	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KPL75_RS20000	COG5504	Zn-dependent protease
KPL75_RS20015	COG0180	Tryptophanyl-tRNA synthetase
KPL75_RS20025	COG4166	transmembrane transport
KPL75_RS20030	COG0601	transmembrane transport
KPL75_RS20035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KPL75_RS20040	COG0444	Belongs to the ABC transporter superfamily
KPL75_RS20045	COG4608	Belongs to the ABC transporter superfamily
KPL75_RS20060	COG0534	Mate efflux family protein
KPL75_RS20065	COG4166	transmembrane transport
KPL75_RS20080	COG0861	Integral membrane protein TerC family
KPL75_RS20085	COG4862	establishment of competence for transformation
KPL75_RS20090	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KPL75_RS20100	COG1164	Oligoendopeptidase f
KPL75_RS20115	COG2346	COG2346, Truncated hemoglobins
KPL75_RS20120	COG4116	CYTH
KPL75_RS20130	COG2357	RelA SpoT domain protein
KPL75_RS20140	COG0564	pseudouridine synthase activity
KPL75_RS20150	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KPL75_RS20155	COG0772	Belongs to the SEDS family
KPL75_RS20160	COG1216	Glycosyl transferase, family 2
KPL75_RS20180	COG0463	Glycosyl transferase, family 2
KPL75_RS20180	COG0457	Tetratricopeptide repeat
KPL75_RS20200	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KPL75_RS20215	COG1091	dTDP-4-dehydrorhamnose reductase activity
KPL75_RS20260	COG2153	protein acetylation
KPL75_RS20265	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KPL75_RS20270	COG2382	esterase
KPL75_RS20295	COG5492	domain, Protein
KPL75_RS20300	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KPL75_RS20310	COG0512	Glutamine amidotransferase of anthranilate synthase
KPL75_RS20310	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KPL75_RS20315	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KPL75_RS20320	COG0134	indole-3-glycerol-phosphate synthase activity
KPL75_RS20325	COG0135	phosphoribosylanthranilate isomerase activity
KPL75_RS20330	COG0133	tryptophan synthase activity
KPL75_RS20335	COG0159	tryptophan synthase activity
KPL75_RS20345	COG1620	l-lactate permease
KPL75_RS20350	COG5634	Uncharacterized conserved protein (DUF2278)
KPL75_RS20390	COG2226	methyltransferase
KPL75_RS20410	COG0508	dehydrogenase complex catalyzes the overall conversion of
KPL75_RS20415	COG0567	Dehydrogenase, E1 component
KPL75_RS20420	COG1476	TRANSCRIPTIONal
KPL75_RS20465	COG1686	Belongs to the peptidase S11 family
KPL75_RS20470	COG0681	Belongs to the peptidase S26 family
KPL75_RS20505	COG1012	belongs to the aldehyde dehydrogenase family
KPL75_RS20515	COG1176	ABC-type spermidine putrescine transport system, permease component I
KPL75_RS20520	COG1177	transmembrane transport
KPL75_RS20525	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KPL75_RS20535	COG2409	Drug exporters of the RND superfamily
KPL75_RS20545	COG0564	pseudouridine synthase activity
KPL75_RS20555	COG2801	Transposase and inactivated derivatives
KPL75_RS20565	COG2340	Cysteine-rich secretory protein family
KPL75_RS20570	COG0247	lactate metabolic process
KPL75_RS20575	COG0277	FAD linked oxidase domain protein
KPL75_RS20580	COG3835	regulator
KPL75_RS20590	COG0745	RESPONSE REGULATOR receiver
KPL75_RS20600	COG2186	Transcriptional regulator
KPL75_RS20615	COG1556	Lactate utilization protein
KPL75_RS20620	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KPL75_RS20630	COG2116	formate transmembrane transporter activity
KPL75_RS20635	COG0861	Integral membrane protein TerC family
KPL75_RS20640	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KPL75_RS20650	COG2030	dehydratase
KPL75_RS20670	COG1028	Short-chain dehydrogenase reductase Sdr
KPL75_RS20675	COG3243	poly(R)-hydroxyalkanoic acid synthase
KPL75_RS20685	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KPL75_RS20700	COG1840	ABC-type Fe3 transport system, periplasmic component
KPL75_RS20705	COG3842	ATPase activity
KPL75_RS20715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KPL75_RS20720	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KPL75_RS20730	COG1349	DNA-binding transcription factor activity
KPL75_RS20740	COG0235	Class ii aldolase
KPL75_RS20750	COG2861	carbohydrate metabolic process
KPL75_RS20760	COG3852	Histidine kinase
KPL75_RS20765	COG1846	Transcriptional regulator
KPL75_RS20775	COG2318	DinB family
KPL75_RS20785	COG5002	protein histidine kinase activity
KPL75_RS20795	COG0720	synthase
KPL75_RS20810	COG4873	Protein conserved in bacteria
KPL75_RS20840	COG1780	Probably involved in ribonucleotide reductase function
KPL75_RS20855	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KPL75_RS20860	COG0531	amino acid
KPL75_RS20865	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KPL75_RS20880	COG2204	response regulator
KPL75_RS20885	COG1012	belongs to the aldehyde dehydrogenase family
KPL75_RS20895	COG1725	Transcriptional regulator
KPL75_RS20900	COG1131	(ABC) transporter
KPL75_RS20910	COG1131	(ABC) transporter
KPL75_RS20920	COG1266	CAAX protease self-immunity
KPL75_RS20930	COG1522	sequence-specific DNA binding
KPL75_RS20940	COG1335	isochorismatase
KPL75_RS20950	COG1619	proteins homologs of microcin C7 resistance protein MccF
KPL75_RS20955	COG2070	2-Nitropropane dioxygenase
KPL75_RS20960	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KPL75_RS20965	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KPL75_RS20970	COG1696	Membrane protein involved in D-alanine export
KPL75_RS20995	COG0716	FMN binding
KPL75_RS21010	COG3173	Aminoglycoside phosphotransferase
KPL75_RS21030	COG0534	Mate efflux family protein
KPL75_RS21050	COG1846	Transcriptional regulator
KPL75_RS21065	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KPL75_RS21075	COG3874	Sporulation protein YtfJ
KPL75_RS21100	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KPL75_RS21105	COG0028	Belongs to the TPP enzyme family
KPL75_RS21110	COG0440	acetolactate synthase activity
KPL75_RS21120	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KPL75_RS21130	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KPL75_RS21140	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KPL75_RS21145	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KPL75_RS21160	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KPL75_RS21165	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KPL75_RS21170	COG0107	imidazoleglycerol-phosphate synthase activity
KPL75_RS21180	COG0140	phosphoribosyl-ATP diphosphatase activity
KPL75_RS21185	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KPL75_RS21200	COG1183	phosphatidylcholine synthase activity
KPL75_RS21205	COG1368	sulfuric ester hydrolase activity
KPL75_RS21215	COG0019	diaminopimelate decarboxylase activity
KPL75_RS21235	COG0529	Catalyzes the synthesis of activated sulfate
KPL75_RS21240	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KPL75_RS21260	COG1648	precorrin-2 dehydrogenase activity
KPL75_RS21265	COG0733	neurotransmitter:sodium symporter activity
KPL75_RS21290	COG1757	Na H antiporter
KPL75_RS21310	COG4758	membrane
KPL75_RS21315	COG4585	Histidine kinase
KPL75_RS21320	COG2197	response regulator
KPL75_RS21330	COG1114	Component of the transport system for branched-chain amino acids
KPL75_RS21380	COG0730	response to heat
KPL75_RS21385	COG0306	phosphate transporter
KPL75_RS21390	COG1392	Phosphate transport regulator
KPL75_RS21395	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KPL75_RS21410	COG3852	Histidine kinase
KPL75_RS21415	COG1801	Protein of unknown function DUF72
KPL75_RS21425	COG0582	viral genome integration into host DNA
KPL75_RS21430	COG5002	protein histidine kinase activity
KPL75_RS21445	COG0392	lysyltransferase activity
KPL75_RS21445	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KPL75_RS21460	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KPL75_RS21465	COG1686	Belongs to the peptidase S11 family
KPL75_RS21470	COG2715	membrane protein required for spore maturation
KPL75_RS21475	COG0700	Nucleoside recognition
KPL75_RS21480	COG1187	pseudouridine synthase activity
KPL75_RS21490	COG1333	cytochrome c biogenesis protein
KPL75_RS21495	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KPL75_RS21500	COG0745	RESPONSE REGULATOR receiver
KPL75_RS21505	COG5002	protein histidine kinase activity
KPL75_RS21510	COG2096	Adenosyltransferase
KPL75_RS21515	COG4942	peptidase
KPL75_RS21525	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KPL75_RS21530	COG1141	Ferredoxin
KPL75_RS21535	COG4955	Helix-turn-helix domain
KPL75_RS21540	COG0514	ATP-dependent DNA helicase (RecQ)
KPL75_RS21545	COG1266	CAAX protease self-immunity
KPL75_RS21555	COG1408	metallophosphoesterase
KPL75_RS21570	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KPL75_RS21590	COG0492	ferredoxin-NADP+ reductase activity
KPL75_RS21595	COG0252	asparaginase activity
KPL75_RS21605	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KPL75_RS21615	COG1304	FMN binding
KPL75_RS21650	COG1160	GTP binding
KPL75_RS21675	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KPL75_RS21690	COG0142	geranyltranstransferase activity
KPL75_RS21695	COG2226	methyltransferase
KPL75_RS21700	COG0142	geranyltranstransferase activity
KPL75_RS21715	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KPL75_RS21725	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KPL75_RS21730	COG0457	Tetratricopeptide repeat
KPL75_RS21735	COG5582	Belongs to the UPF0302 family
KPL75_RS21750	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KPL75_RS21760	COG4347	Protein of unknown function (DUF1405)
KPL75_RS21775	COG2738	Putative neutral zinc metallopeptidase
KPL75_RS21785	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KPL75_RS21790	COG1694	Mazg nucleotide pyrophosphohydrolase
KPL75_RS21795	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KPL75_RS21800	COG1803	Methylglyoxal synthase
KPL75_RS21805	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KPL75_RS21810	COG0438	transferase activity, transferring glycosyl groups
KPL75_RS21815	COG0617	tRNA 3'-terminal CCA addition
KPL75_RS21825	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KPL75_RS21830	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KPL75_RS21840	COG1199	ATP-dependent helicase activity
KPL75_RS21840	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KPL75_RS21860	COG3935	DnaD domain protein
KPL75_RS21865	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KPL75_RS21875	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KPL75_RS21875	COG4499	WXG100 protein secretion system (Wss), protein YukC
KPL75_RS21880	COG3331	DNA recombination
KPL75_RS21915	COG4474	Belongs to the UPF0398 family
KPL75_RS21920	COG3599	regulation of cell shape
KPL75_RS21930	COG0116	Belongs to the methyltransferase superfamily
KPL75_RS21940	COG1199	ATP-dependent helicase activity
KPL75_RS21945	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KPL75_RS21950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KPL75_RS21955	COG0024	Methionine aminopeptidase
KPL75_RS21965	COG2233	PERMEase
KPL75_RS21970	COG2311	Membrane
KPL75_RS21980	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KPL75_RS21990	COG0456	acetyltransferase
KPL75_RS22020	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KPL75_RS22045	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KPL75_RS22060	COG1215	transferase activity, transferring glycosyl groups
KPL75_RS22065	COG0438	transferase activity, transferring glycosyl groups
KPL75_RS22100	COG0328	RNA-DNA hybrid ribonuclease activity
KPL75_RS22135	COG3403	YqcI/YcgG family
KPL75_RS22140	COG1280	lysine exporter protein (LysE YggA)
KPL75_RS22155	COG3162	membrane
KPL75_RS22160	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KPL75_RS22165	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KPL75_RS22175	COG0475	glutathione-regulated potassium exporter activity
KPL75_RS22180	COG4978	Transcriptional regulator
KPL75_RS22180	COG0789	Transcriptional regulator
KPL75_RS22190	COG2323	membrane
KPL75_RS22195	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KPL75_RS22250	COG1923	regulation of RNA biosynthetic process
KPL75_RS22260	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KPL75_RS22265	COG1360	Flagellar Motor Protein
KPL75_RS22270	COG2201	protein-glutamate methylesterase activity
KPL75_RS22275	COG2198	Histidine kinase
KPL75_RS22275	COG0643	Histidine kinase
KPL75_RS22280	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KPL75_RS22280	COG1776	CheC inhibitor of MCP methylation
KPL75_RS22300	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KPL75_RS22320	COG1256	bacterial-type flagellum assembly
KPL75_RS22325	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KPL75_RS22345	COG1815	bacterial-type flagellum-dependent cell motility
KPL75_RS22350	COG1558	bacterial-type flagellum-dependent cell motility
KPL75_RS22360	COG1766	The M ring may be actively involved in energy transduction
KPL75_RS22365	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KPL75_RS22375	COG1157	protein secretion by the type III secretion system
KPL75_RS22410	COG0835	chemotaxis
KPL75_RS22410	COG0784	Response regulator, receiver
KPL75_RS22430	COG0861	Integral membrane protein TerC family
KPL75_RS22440	COG3383	formate dehydrogenase (NAD+) activity
KPL75_RS22445	COG2427	Protein of unknown function (DUF1641)
KPL75_RS22450	COG5609	conserved protein (DUF2294)
KPL75_RS22455	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KPL75_RS22465	COG2116	formate transmembrane transporter activity
KPL75_RS22470	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KPL75_RS22475	COG0303	'Molybdopterin
KPL75_RS22480	COG0314	molybdopterin synthase activity
KPL75_RS22485	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KPL75_RS22495	COG0489	protein tyrosine kinase activity
KPL75_RS22500	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KPL75_RS22505	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KPL75_RS22510	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KPL75_RS22515	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KPL75_RS22520	COG0741	lytic transglycosylase activity
KPL75_RS22530	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KPL75_RS22535	COG1776	CheC inhibitor of MCP methylation
KPL75_RS22535	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KPL75_RS22545	COG1338	Plays a role in the flagellum-specific transport system
KPL75_RS22550	COG1987	bacterial-type flagellum assembly
KPL75_RS22560	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KPL75_RS22565	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KPL75_RS22570	COG1419	protein localization to endoplasmic reticulum
KPL75_RS22575	COG4786	Flagellar basal body rod
KPL75_RS22615	COG2329	Antibiotic biosynthesis monooxygenase
KPL75_RS22650	COG0583	DNA-binding transcription factor activity
KPL75_RS22655	COG3842	ATPase activity
KPL75_RS22720	COG1846	Transcriptional regulator
KPL75_RS22730	COG0367	asparagine synthase
KPL75_RS22770	COG1216	Glycosyl transferase, family 2
KPL75_RS22770	COG0438	transferase activity, transferring glycosyl groups
KPL75_RS22775	COG1757	Na H antiporter
KPL75_RS22805	COG0534	Mate efflux family protein
KPL75_RS22810	COG3340	Belongs to the peptidase S51 family
KPL75_RS22830	COG0785	Cytochrome C biogenesis protein
KPL75_RS22835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KPL75_RS22850	COG3048	D-serine ammonia-lyase activity
KPL75_RS22855	COG2733	membrane
KPL75_RS22890	COG1131	(ABC) transporter
KPL75_RS22910	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KPL75_RS22915	COG2801	Transposase and inactivated derivatives
KPL75_RS22965	COG0528	UMP kinase activity
KPL75_RS22975	COG1027	Aspartate ammonia-lyase
KPL75_RS22980	COG0281	malic enzyme
KPL75_RS22985	COG4191	Histidine kinase
KPL75_RS22990	COG0784	Response regulator, receiver
KPL75_RS22995	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KPL75_RS23050	COG2814	Major facilitator Superfamily
KPL75_RS23070	COG1695	Transcriptional regulator
KPL75_RS23080	COG0477	Major facilitator Superfamily
KPL75_RS23095	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KPL75_RS23100	COG2223	nitrite transmembrane transporter activity
KPL75_RS23105	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KPL75_RS23120	COG2244	polysaccharide biosynthetic process
KPL75_RS23125	COG0733	neurotransmitter:sodium symporter activity
KPL75_RS23130	COG5566	PFAM Mor transcription activator
KPL75_RS23135	COG2323	membrane
KPL75_RS23150	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KPL75_RS23165	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KPL75_RS23190	COG2814	Major facilitator Superfamily
KPL75_RS23200	COG3384	dioxygenase
KPL75_RS23210	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KPL75_RS23250	COG4166	transmembrane transport
KPL75_RS23260	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KPL75_RS23280	COG1914	H( )-stimulated, divalent metal cation uptake system
KPL75_RS23285	COG1054	Belongs to the UPF0176 family
KPL75_RS23295	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KPL75_RS23300	COG0531	amino acid
KPL75_RS23340	COG0745	RESPONSE REGULATOR receiver
KPL75_RS23345	COG5002	protein histidine kinase activity
KPL75_RS23370	COG2390	Transcriptional regulator
KPL75_RS23380	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KPL75_RS23385	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KPL75_RS23390	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KPL75_RS23405	COG4846	Membrane protein involved in cytochrome C biogenesis
KPL75_RS23425	COG0583	DNA-binding transcription factor activity
KPL75_RS23440	COG0006	proline dipeptidase activity
KPL75_RS23450	COG2132	Multicopper oxidase
KPL75_RS23460	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KPL75_RS23470	COG0583	DNA-binding transcription factor activity
KPL75_RS23490	COG1114	Component of the transport system for branched-chain amino acids
KPL75_RS23500	COG4641	Protein conserved in bacteria
KPL75_RS23510	COG1276	copper resistance
KPL75_RS23510	COG2372	response to copper ion
KPL75_RS23515	COG4549	nuclear export factor GLE1
KPL75_RS23525	COG0697	spore germination
KPL75_RS23530	COG0583	DNA-binding transcription factor activity
KPL75_RS23535	COG1959	2 iron, 2 sulfur cluster binding
KPL75_RS23540	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KPL75_RS23545	COG0778	Nitroreductase
KPL75_RS23555	COG0628	permease
KPL75_RS23570	COG1231	oxidoreductase activity
KPL75_RS23575	COG0523	cobalamin synthesis protein
KPL75_RS23585	COG0411	ABC transporter
KPL75_RS23605	COG0583	DNA-binding transcription factor activity
KPL75_RS23615	COG1942	4-Oxalocrotonate Tautomerase
KPL75_RS23630	COG0346	lactoylglutathione lyase activity
KPL75_RS23640	COG1271	oxidase subunit
KPL75_RS23645	COG1294	oxidase, subunit
KPL75_RS23650	COG4988	ABC transporter
KPL75_RS23655	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KPL75_RS23680	COG1619	proteins homologs of microcin C7 resistance protein MccF
KPL75_RS23685	COG1686	Belongs to the peptidase S11 family
KPL75_RS23700	COG1388	LysM domain
KPL75_RS23700	COG0791	NLP P60 protein
KPL75_RS23710	COG1132	(ABC) transporter
KPL75_RS23715	COG0745	RESPONSE REGULATOR receiver
KPL75_RS23720	COG5002	protein histidine kinase activity
KPL75_RS23725	COG0300	oxidoreductase activity
KPL75_RS23730	COG4122	O-methyltransferase activity
KPL75_RS23760	COG0460	homoserine dehydrogenase
KPL75_RS23770	COG0083	homoserine kinase activity
KPL75_RS23785	COG1316	TRANSCRIPTIONal
KPL75_RS23795	COG0745	RESPONSE REGULATOR receiver
KPL75_RS23800	COG5002	protein histidine kinase activity
KPL75_RS23815	COG1285	pathogenesis
KPL75_RS23820	COG1247	-acetyltransferase
KPL75_RS23840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KPL75_RS23850	COG1082	Xylose isomerase domain protein TIM barrel
KPL75_RS23860	COG2814	Major facilitator Superfamily
KPL75_RS23865	COG1279	arginine transmembrane transporter activity
KPL75_RS23870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KPL75_RS23880	COG1752	Esterase of the alpha-beta hydrolase superfamily
KPL75_RS23915	COG0577	efflux transmembrane transporter activity
KPL75_RS23920	COG2002	toxin-antitoxin pair type II binding
KPL75_RS23950	COG1404	Belongs to the peptidase S8 family
KPL75_RS23955	COG0640	Transcriptional regulator
KPL75_RS23960	COG0667	Aldo Keto reductase
KPL75_RS23965	COG2814	Major facilitator Superfamily
KPL75_RS24005	COG3949	Membrane
KPL75_RS24010	COG0783	Belongs to the Dps family
KPL75_RS24025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KPL75_RS24035	COG1231	oxidoreductase activity
KPL75_RS24045	COG4989	oxidoreductase activity
KPL75_RS24050	COG0523	cobalamin synthesis protein
KPL75_RS24065	COG0456	acetyltransferase
KPL75_RS24070	COG0803	Belongs to the bacterial solute-binding protein 9 family
KPL75_RS24085	COG1902	pentaerythritol trinitrate reductase activity
KPL75_RS24090	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KPL75_RS24100	COG4166	transmembrane transport
KPL75_RS24105	COG0346	lactoylglutathione lyase activity
KPL75_RS24115	COG0406	alpha-ribazole phosphatase activity
KPL75_RS24125	COG5337	Spore coat protein CotH
KPL75_RS24130	COG1051	belongs to the nudix hydrolase family
KPL75_RS24135	COG0586	Pfam SNARE associated Golgi protein
KPL75_RS24140	COG2244	polysaccharide biosynthetic process
KPL75_RS24150	COG0701	Predicted permease
KPL75_RS24155	COG3689	TIGRFAM TIGR03943 family protein
KPL75_RS24160	COG1607	acyl-coa hydrolase
KPL75_RS24170	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KPL75_RS24185	COG0702	epimerase
KPL75_RS24190	COG2839	Protein conserved in bacteria
KPL75_RS24195	COG1253	flavin adenine dinucleotide binding
KPL75_RS24220	COG1114	Component of the transport system for branched-chain amino acids
KPL75_RS24225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KPL75_RS24240	COG0860	N-Acetylmuramoyl-L-alanine amidase
KPL75_RS24250	COG1876	peptidase activity
KPL75_RS24265	COG2211	Major facilitator Superfamily
KPL75_RS24290	COG0561	phosphatase activity
KPL75_RS24300	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KPL75_RS24315	COG1819	glycosyl
KPL75_RS24320	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KPL75_RS24325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KPL75_RS24350	COG0456	acetyltransferase
KPL75_RS24385	COG4499	WXG100 protein secretion system (Wss), protein YukC
KPL75_RS24470	COG3874	Sporulation protein YtfJ
KPL75_RS24495	COG2226	methyltransferase
KPL75_RS24520	COG0346	lactoylglutathione lyase activity
KPL75_RS24530	COG0604	alcohol dehydrogenase
KPL75_RS24535	COG1595	DNA-templated transcription, initiation
KPL75_RS24555	COG0426	domain, Protein
KPL75_RS24555	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KPL75_RS24565	COG0386	Belongs to the glutathione peroxidase family
KPL75_RS24570	COG1305	Transglutaminase-like
KPL75_RS24575	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KPL75_RS24580	COG0714	Associated with various cellular activities
KPL75_RS24585	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KPL75_RS24590	COG1140	nitrate reductase beta subunit
KPL75_RS24595	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KPL75_RS24600	COG2181	nitrate reductase activity
KPL75_RS24605	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KPL75_RS24610	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KPL75_RS24615	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KPL75_RS24620	COG0303	'Molybdopterin
KPL75_RS24625	COG0314	molybdopterin synthase activity
KPL75_RS24635	COG2223	nitrite transmembrane transporter activity
KPL75_RS24650	COG1648	precorrin-2 dehydrogenase activity
KPL75_RS24660	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KPL75_RS24660	COG1587	Uroporphyrinogen-III synthase
KPL75_RS24665	COG2146	nitrite reductase [NAD(P)H] activity
KPL75_RS24670	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KPL75_RS24675	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
KPL75_RS24710	COG2359	stage V sporulation protein S
KPL75_RS24720	COG1418	mRNA catabolic process
KPL75_RS24725	COG0488	(ABC) transporter
KPL75_RS24740	COG0629	single-stranded DNA binding
KPL75_RS24765	COG1413	lyase activity
KPL75_RS24780	COG2521	methyltransferase
KPL75_RS24780	COG2136	Putative SAM-dependent methyltransferase
KPL75_RS24830	COG0017	Asparaginyl-tRNA synthetase
KPL75_RS24835	COG0733	neurotransmitter:sodium symporter activity
KPL75_RS24860	COG2610	gluconate transmembrane transporter activity
KPL75_RS24865	COG1454	alcohol dehydrogenase
KPL75_RS24870	COG1794	racemase activity, acting on amino acids and derivatives
KPL75_RS24880	COG0456	acetyltransferase
KPL75_RS24885	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KPL75_RS24895	COG1131	(ABC) transporter
KPL75_RS24900	COG4473	ABC transporter
KPL75_RS24910	COG0546	phosphoglycolate phosphatase activity
KPL75_RS24950	COG0768	penicillin binding
KPL75_RS24965	COG1272	protein, Hemolysin III
KPL75_RS24970	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KPL75_RS24975	COG0805	protein transport
KPL75_RS24985	COG1307	EDD domain protein, DegV family
KPL75_RS24990	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KPL75_RS24995	COG1999	signal sequence binding
KPL75_RS25000	COG0071	Belongs to the small heat shock protein (HSP20) family
KPL75_RS25005	COG0367	asparagine synthase
KPL75_RS25020	COG0860	N-Acetylmuramoyl-L-alanine amidase
KPL75_RS25025	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KPL75_RS25030	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KPL75_RS25045	COG1335	isochorismatase
KPL75_RS25050	COG1051	belongs to the nudix hydrolase family
KPL75_RS25055	COG0668	transmembrane transport
KPL75_RS25060	COG2203	Gaf domain
KPL75_RS25060	COG4585	Histidine kinase
KPL75_RS25065	COG2197	response regulator
KPL75_RS25070	COG1737	Transcriptional regulator
KPL75_RS25075	COG1064	alcohol dehydrogenase
KPL75_RS25090	COG1070	Carbohydrate kinase
KPL75_RS25100	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KPL75_RS25135	COG0517	IMP dehydrogenase activity
KPL75_RS25135	COG1125	glycine betaine transport
KPL75_RS25140	COG1174	glycine betaine transport
KPL75_RS25175	COG1253	flavin adenine dinucleotide binding
KPL75_RS25180	COG1012	belongs to the aldehyde dehydrogenase family
KPL75_RS25185	COG5506	Protein of unknown function (DUF1694)
KPL75_RS25200	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KPL75_RS25205	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KPL75_RS25210	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KPL75_RS25215	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KPL75_RS25220	COG0456	acetyltransferase
KPL75_RS25225	COG3829	transcription factor binding
KPL75_RS25230	COG1509	lysine 2,3-aminomutase activity
KPL75_RS25240	COG4479	Belongs to the UPF0346 family
KPL75_RS25265	COG3064	Membrane
KPL75_RS25265	COG0515	serine threonine protein kinase
KPL75_RS25265	COG4991	sh3 domain protein
KPL75_RS25275	COG0671	phosphoesterase, PA-phosphatase related
KPL75_RS25280	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KPL75_RS25290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KPL75_RS25295	COG0582	viral genome integration into host DNA
KPL75_RS25310	COG5377	YqaJ viral recombinase family
KPL75_RS25340	COG2801	Transposase and inactivated derivatives
KPL75_RS25365	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KPL75_RS25385	COG1028	Short-chain dehydrogenase reductase Sdr
KPL75_RS25405	COG4499	WXG100 protein secretion system (Wss), protein YukC
KPL75_RS25405	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KPL75_RS25415	COG2814	Major facilitator Superfamily
KPL75_RS25420	COG0372	Belongs to the citrate synthase family
KPL75_RS25425	COG2079	MmgE PrpD family protein
KPL75_RS25430	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KPL75_RS25435	COG1960	acyl-CoA dehydrogenase activity
KPL75_RS25440	COG2084	Dehydrogenase
KPL75_RS25445	COG1012	belongs to the aldehyde dehydrogenase family
KPL75_RS25450	COG1280	lysine exporter protein (LysE YggA)
KPL75_RS25455	COG1024	Enoyl-CoA hydratase
KPL75_RS25470	COG0420	3'-5' exonuclease activity
KPL75_RS25475	COG0419	ATPase involved in DNA repair
KPL75_RS25485	COG3397	chitin binding
KPL75_RS25490	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KPL75_RS25505	COG2223	nitrite transmembrane transporter activity
KPL75_RS25510	COG1028	Short-chain dehydrogenase reductase Sdr
KPL75_RS25515	COG1169	isochorismate synthase
KPL75_RS25520	COG1021	2,3-dihydroxybenzoate-AMP ligase
KPL75_RS25525	COG1535	isochorismatase
KPL75_RS25525	COG3433	isochorismatase activity
KPL75_RS25530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KPL75_RS25535	COG3251	PFAM MbtH domain protein
KPL75_RS25540	COG2814	Major facilitator Superfamily
KPL75_RS25555	COG0776	regulation of translation
KPL75_RS25565	COG1115	amino acid carrier protein
KPL75_RS25585	COG2329	Antibiotic biosynthesis monooxygenase
KPL75_RS25590	COG1187	pseudouridine synthase activity
KPL75_RS25595	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KPL75_RS25675	COG1136	(ABC) transporter
KPL75_RS25685	COG0596	Alpha beta hydrolase
KPL75_RS25690	COG2814	Major facilitator Superfamily
KPL75_RS25705	COG0028	Belongs to the TPP enzyme family
KPL75_RS25715	COG2226	methyltransferase
KPL75_RS25720	COG1253	flavin adenine dinucleotide binding
KPL75_RS25755	COG1846	Transcriptional regulator
KPL75_RS25765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KPL75_RS25770	COG1309	transcriptional regulator
KPL75_RS25800	COG1247	-acetyltransferase
KPL75_RS25835	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KPL75_RS25850	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KPL75_RS25880	COG0561	phosphatase activity
KPL75_RS25890	COG0583	DNA-binding transcription factor activity
KPL75_RS25895	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KPL75_RS25915	COG0583	DNA-binding transcription factor activity
KPL75_RS25920	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KPL75_RS25925	COG2258	MOSC domain
KPL75_RS25935	COG1132	(ABC) transporter
KPL75_RS25940	COG1132	(ABC) transporter
KPL75_RS25955	COG1396	sequence-specific DNA binding
KPL75_RS25990	COG1595	DNA-templated transcription, initiation
KPL75_RS26015	COG1649	PFAM Uncharacterised BCR, COG1649
KPL75_RS26040	COG2971	BadF BadG BcrA BcrD
KPL75_RS26060	COG1846	Transcriptional regulator
KPL75_RS26095	COG1309	transcriptional regulator
KPL75_RS26110	COG1136	(ABC) transporter
KPL75_RS26125	COG2226	methyltransferase
KPL75_RS26165	COG2195	Cleaves the N-terminal amino acid of tripeptides
KPL75_RS26185	COG1686	Belongs to the peptidase S11 family
KPL75_RS26215	COG1136	(ABC) transporter
KPL75_RS26220	COG0577	efflux transmembrane transporter activity
KPL75_RS26230	COG2205	protein histidine kinase activity
KPL75_RS26235	COG1136	(ABC) transporter
KPL75_RS26240	COG0577	efflux transmembrane transporter activity
KPL75_RS26250	COG0768	penicillin binding
KPL75_RS26255	COG1595	DNA-templated transcription, initiation
KPL75_RS26265	COG0768	penicillin binding
KPL75_RS26270	COG0768	penicillin binding
KPL75_RS26305	COG1316	TRANSCRIPTIONal
KPL75_RS26310	COG2239	Acts as a magnesium transporter
KPL75_RS26315	COG0772	Belongs to the SEDS family
KPL75_RS26325	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KPL75_RS26345	COG0697	spore germination
KPL75_RS26375	COG3397	chitin binding
KPL75_RS26390	COG1408	metallophosphoesterase
KPL75_RS26400	COG1131	(ABC) transporter
KPL75_RS26410	COG1309	transcriptional regulator
KPL75_RS26420	COG1960	acyl-CoA dehydrogenase activity
KPL75_RS26425	COG0439	Biotin carboxylase
KPL75_RS26430	COG0511	ligase activity, forming carbon-carbon bonds
KPL75_RS26435	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KPL75_RS26440	COG1024	Enoyl-CoA hydratase
KPL75_RS26445	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KPL75_RS26450	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KPL75_RS26475	COG0572	uridine kinase
KPL75_RS26490	COG1686	Belongs to the peptidase S11 family
KPL75_RS26515	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KPL75_RS26555	COG1136	(ABC) transporter
KPL75_RS26555	COG0577	efflux transmembrane transporter activity
KPL75_RS26565	COG0745	RESPONSE REGULATOR receiver
KPL75_RS26570	COG5002	protein histidine kinase activity
KPL75_RS26580	COG2207	Transcriptional regulator
KPL75_RS26610	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KPL75_RS26630	COG0693	protein deglycase activity
KPL75_RS26650	COG0789	Transcriptional regulator
KPL75_RS26650	COG4978	Transcriptional regulator
KPL75_RS26660	COG1028	Short-chain dehydrogenase reductase Sdr
KPL75_RS26665	COG1733	regulation of RNA biosynthetic process
KPL75_RS26690	COG1309	transcriptional regulator
KPL75_RS26720	COG0697	spore germination
KPL75_RS26725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KPL75_RS26740	COG2368	4-hydroxyphenylacetate
KPL75_RS26755	COG1063	alcohol dehydrogenase
KPL75_RS26765	COG2323	membrane
KPL75_RS26780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KPL75_RS26785	COG0697	spore germination
KPL75_RS26805	COG0201	protein transport
KPL75_RS26835	COG1523	belongs to the glycosyl hydrolase 13 family
KPL75_RS26840	COG1073	alpha beta
KPL75_RS26865	COG0577	efflux transmembrane transporter activity
KPL75_RS26870	COG1136	(ABC) transporter
KPL75_RS26905	COG5002	protein histidine kinase activity
KPL75_RS26910	COG0745	RESPONSE REGULATOR receiver
KPL75_RS26915	COG1011	Hydrolase
KPL75_RS26940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KPL75_RS26945	COG1183	phosphatidylcholine synthase activity
KPL75_RS26950	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KPL75_RS26960	COG1132	(ABC) transporter
KPL75_RS26970	COG3961	Belongs to the TPP enzyme family
KPL75_RS26990	COG0322	excinuclease ABC activity
KPL75_RS27015	COG2318	DinB family
KPL75_RS27030	COG4667	esterase of the alpha-beta hydrolase superfamily
KPL75_RS27050	COG3878	Protein conserved in bacteria
KPL75_RS27070	COG1051	belongs to the nudix hydrolase family
KPL75_RS27075	COG0592	DNA-directed DNA polymerase activity
KPL75_RS27085	COG2223	nitrite transmembrane transporter activity
KPL75_RS27095	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KPL75_RS27120	COG0697	spore germination
KPL75_RS27125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KPL75_RS27145	COG0584	glycerophosphoryl diester phosphodiesterase
KPL75_RS27160	COG2814	Major facilitator Superfamily
KPL75_RS27205	COG0768	penicillin binding
KPL75_RS27210	COG0671	phosphoesterase, PA-phosphatase related
KPL75_RS27215	COG0604	alcohol dehydrogenase
KPL75_RS27220	COG5002	protein histidine kinase activity
KPL75_RS27225	COG0745	RESPONSE REGULATOR receiver
KPL75_RS27235	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KPL75_RS27245	COG2205	protein histidine kinase activity
KPL75_RS27260	COG1122	ATPase activity
KPL75_RS27265	COG4720	Psort location CytoplasmicMembrane, score
KPL75_RS27270	COG1794	racemase activity, acting on amino acids and derivatives
KPL75_RS27275	COG1819	glycosyl
KPL75_RS27285	COG0768	penicillin binding
KPL75_RS27290	COG5002	protein histidine kinase activity
KPL75_RS27405	COG1671	Belongs to the UPF0178 family
KPL75_RS27435	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls