locus-tag	class	description
OXB_RS00005	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OXB_RS00015	COG1506	peptidase
OXB_RS00020	COG0494	nUDIX hydrolase
OXB_RS00035	COG0783	Belongs to the Dps family
OXB_RS00040	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
OXB_RS00055	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
OXB_RS00060	COG0596	Alpha beta hydrolase
OXB_RS00070	COG1169	isochorismate synthase
OXB_RS00075	COG1575	Belongs to the MenA family. Type 1 subfamily
OXB_RS00080	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OXB_RS00215	COG1285	pathogenesis
OXB_RS00225	COG1979	alcohol dehydrogenase
OXB_RS00235	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OXB_RS00240	COG1012	belongs to the aldehyde dehydrogenase family
OXB_RS00245	COG3829	transcription factor binding
OXB_RS00250	COG1098	S1 RNA binding domain
OXB_RS00265	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
OXB_RS00275	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OXB_RS00280	COG2814	Major facilitator Superfamily
OXB_RS00285	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OXB_RS00300	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OXB_RS00300	COG2111	Na H antiporter
OXB_RS00305	COG2111	Na H antiporter
OXB_RS00310	COG1006	Multisubunit Na H antiporter MnhC subunit
OXB_RS00315	COG0651	ATP synthesis coupled electron transport
OXB_RS00320	COG1863	multisubunit Na H antiporter MnhE subunit
OXB_RS00325	COG2212	antiporter activity
OXB_RS00330	COG1320	monovalent cation:proton antiporter activity
OXB_RS00340	COG0753	catalase activity
OXB_RS00350	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
OXB_RS00360	COG1252	NADH dehydrogenase
OXB_RS00365	COG0316	Belongs to the HesB IscA family
OXB_RS00375	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
OXB_RS00380	COG4837	Protein of unknown function (DUF1462)
OXB_RS00385	COG1252	NADH dehydrogenase
OXB_RS00395	COG0647	UMP catabolic process
OXB_RS00400	COG2445	Protein of unknown function DUF86
OXB_RS00405	COG4470	Protein conserved in bacteria
OXB_RS00410	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OXB_RS00420	COG0733	neurotransmitter:sodium symporter activity
OXB_RS00425	COG1757	Na H antiporter
OXB_RS00435	COG0737	Belongs to the 5'-nucleotidase family
OXB_RS00440	COG0730	response to heat
OXB_RS00445	COG1801	Protein of unknown function DUF72
OXB_RS00455	COG0719	Fe-S assembly protein
OXB_RS00460	COG0822	iron-sulfur transferase activity
OXB_RS00465	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OXB_RS00470	COG0719	Fe-S assembly protein
OXB_RS00475	COG0396	ATPase activity
OXB_RS00485	COG1464	Belongs to the NlpA lipoprotein family
OXB_RS00490	COG2011	ABC-type metal ion transport system permease component
OXB_RS00495	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OXB_RS00500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OXB_RS00505	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
OXB_RS00510	COG0509	glycine decarboxylation via glycine cleavage system
OXB_RS00515	COG1393	Belongs to the ArsC family
OXB_RS00520	COG1960	acyl-CoA dehydrogenase activity
OXB_RS00525	COG0183	Belongs to the thiolase family
OXB_RS00530	COG1024	Enoyl-CoA hydratase
OXB_RS00530	COG1250	3-hydroxyacyl-CoA dehydrogenase
OXB_RS00535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OXB_RS00550	COG1366	Belongs to the anti-sigma-factor antagonist family
OXB_RS00555	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OXB_RS00570	COG1595	DNA-templated transcription, initiation
OXB_RS00585	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OXB_RS00590	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OXB_RS00595	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OXB_RS00600	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OXB_RS00605	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OXB_RS00610	COG0640	Transcriptional regulator
OXB_RS00620	COG2271	Major facilitator Superfamily
OXB_RS00625	COG1473	amidohydrolase
OXB_RS00645	COG0617	tRNA 3'-terminal CCA addition
OXB_RS00645	COG3620	sequence-specific DNA binding
OXB_RS00645	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
OXB_RS00660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OXB_RS00670	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
OXB_RS00675	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
OXB_RS00685	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OXB_RS00695	COG0431	NADPH-dependent FMN reductase
OXB_RS00700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OXB_RS00710	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OXB_RS00720	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OXB_RS00770	COG5002	protein histidine kinase activity
OXB_RS00780	COG2311	Membrane
OXB_RS00795	COG2264	protein methyltransferase activity
OXB_RS00820	COG3177	Filamentation induced by cAMP protein fic
OXB_RS00830	COG0557	exoribonuclease II activity
OXB_RS00840	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
OXB_RS00865	COG0126	phosphoglycerate kinase activity
OXB_RS00890	COG1704	LemA family
OXB_RS00905	COG0352	thiamine-phosphate diphosphorylase activity
OXB_RS00910	COG2104	thiamine diphosphate biosynthetic process
OXB_RS00915	COG2022	thiamine diphosphate biosynthetic process
OXB_RS00920	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OXB_RS00935	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OXB_RS00945	COG0391	Required for morphogenesis under gluconeogenic growth conditions
OXB_RS00955	COG1051	belongs to the nudix hydrolase family
OXB_RS00960	COG0492	ferredoxin-NADP+ reductase activity
OXB_RS00965	COG0457	Tetratricopeptide repeat
OXB_RS00970	COG0110	maltose O-acetyltransferase activity
OXB_RS00975	COG0546	phosphoglycolate phosphatase activity
OXB_RS00980	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
OXB_RS00990	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
OXB_RS00995	COG4372	Transposase
OXB_RS01010	COG3595	metallopeptidase activity
OXB_RS01015	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OXB_RS01020	COG0556	nucleotide-excision repair
OXB_RS01035	COG1131	(ABC) transporter
OXB_RS01060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OXB_RS01070	COG3481	metal-dependent phosphohydrolase, HD sub domain
OXB_RS01075	COG4717	serine-type aminopeptidase activity
OXB_RS01080	COG0420	3'-5' exonuclease activity
OXB_RS01085	COG1668	transmembrane transport
OXB_RS01090	COG4152	abc transporter atp-binding protein
OXB_RS01100	COG1476	TRANSCRIPTIONal
OXB_RS01110	COG1803	Methylglyoxal synthase
OXB_RS01115	COG1366	Belongs to the anti-sigma-factor antagonist family
OXB_RS01120	COG1024	Enoyl-CoA hydratase
OXB_RS01125	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OXB_RS01145	COG3871	stress protein (general stress protein 26)
OXB_RS01150	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OXB_RS01170	COG1253	flavin adenine dinucleotide binding
OXB_RS01175	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OXB_RS01180	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OXB_RS01180	COG3153	acetyltransferase
OXB_RS01185	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
OXB_RS01190	COG3118	belongs to the thioredoxin family
OXB_RS01195	COG0564	pseudouridine synthase activity
OXB_RS01205	COG2252	PERMEase
OXB_RS01215	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OXB_RS01220	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OXB_RS01225	COG3382	B3 4 domain protein
OXB_RS01360	COG0735	belongs to the Fur family
OXB_RS01370	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OXB_RS01380	COG4129	membrane
OXB_RS01385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OXB_RS01390	COG0601	transmembrane transport
OXB_RS01395	COG0747	negative chemotaxis
OXB_RS01400	COG4608	Belongs to the ABC transporter superfamily
OXB_RS01405	COG0444	Belongs to the ABC transporter superfamily
OXB_RS01410	COG1132	(ABC) transporter
OXB_RS01415	COG3557	Belongs to the UPF0374 family
OXB_RS01430	COG1988	membrane-bound metal-dependent
OXB_RS01445	COG2137	regulation of response to DNA damage stimulus
OXB_RS01450	COG1090	epimerase
OXB_RS01475	COG2217	Heavy metal translocating P-type atpase
OXB_RS01480	COG1295	ribonuclease BN
OXB_RS01490	COG1115	amino acid carrier protein
OXB_RS01495	COG4840	Belongs to the UPF0435 family
OXB_RS01500	COG1360	Flagellar Motor Protein
OXB_RS01505	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
OXB_RS01510	COG2309	aminopeptidase activity
OXB_RS01515	COG0288	reversible hydration of carbon dioxide
OXB_RS01520	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OXB_RS01530	COG3859	Proton-coupled thiamine transporter YuaJ
OXB_RS01540	COG0024	Methionine aminopeptidase
OXB_RS01545	COG0513	Belongs to the DEAD box helicase family
OXB_RS01550	COG1794	racemase activity, acting on amino acids and derivatives
OXB_RS01565	COG0840	transmembrane signaling receptor activity
OXB_RS01570	COG0840	transmembrane signaling receptor activity
OXB_RS01575	COG0109	protoheme IX farnesyltransferase activity
OXB_RS01580	COG1126	abc transporter atp-binding protein
OXB_RS01585	COG0765	amino acid transport
OXB_RS01590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OXB_RS01600	COG0683	leucine binding
OXB_RS01615	COG1022	Amp-dependent synthetase and ligase
OXB_RS01625	COG1366	Belongs to the anti-sigma-factor antagonist family
OXB_RS01630	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OXB_RS01640	COG3584	3D domain protein
OXB_RS01640	COG1388	LysM domain
OXB_RS01645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OXB_RS01650	COG0840	transmembrane signaling receptor activity
OXB_RS01655	COG1405	negative regulation of cell septum assembly
OXB_RS01655	COG3012	SEC-C Motif Domain Protein
OXB_RS01675	COG1115	amino acid carrier protein
OXB_RS01680	COG0346	lactoylglutathione lyase activity
OXB_RS01735	COG0071	Belongs to the small heat shock protein (HSP20) family
OXB_RS01740	COG4372	Transposase
OXB_RS01750	COG3546	catalase activity
OXB_RS01765	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OXB_RS01770	COG1294	oxidase, subunit
OXB_RS01775	COG1271	oxidase subunit
OXB_RS01780	COG0494	nUDIX hydrolase
OXB_RS01785	COG1597	lipid kinase activity
OXB_RS01795	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OXB_RS01800	COG0154	amidase activity
OXB_RS01805	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OXB_RS01810	COG4851	CamS sex pheromone cAM373 precursor
OXB_RS01820	COG0210	DNA helicase
OXB_RS01830	COG4496	protein, YerC YecD
OXB_RS01835	COG1470	cell adhesion involved in biofilm formation
OXB_RS01840	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OXB_RS01850	COG0697	spore germination
OXB_RS01870	COG0151	Belongs to the GarS family
OXB_RS01880	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OXB_RS01890	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
OXB_RS01905	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OXB_RS01910	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OXB_RS01915	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
OXB_RS01925	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
OXB_RS01945	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OXB_RS01970	COG2252	PERMEase
OXB_RS01975	COG0519	Catalyzes the synthesis of GMP from XMP
OXB_RS01975	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OXB_RS01980	COG1305	Transglutaminase-like
OXB_RS01985	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
OXB_RS01990	COG0714	Associated with various cellular activities
OXB_RS02000	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
OXB_RS02005	COG0656	L-ascorbic acid biosynthetic process
OXB_RS02010	COG0626	cystathionine gamma-synthase activity
OXB_RS02015	COG0626	cystathionine gamma-synthase activity
OXB_RS02020	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
OXB_RS02060	COG1556	Lactate utilization protein
OXB_RS02065	COG1139	Iron-sulfur cluster binding protein
OXB_RS02070	COG0247	lactate metabolic process
OXB_RS02080	COG0488	(ABC) transporter
OXB_RS02095	COG1846	Transcriptional regulator
OXB_RS02100	COG2046	Belongs to the sulfate adenylyltransferase family
OXB_RS02110	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OXB_RS02115	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
OXB_RS02115	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
OXB_RS02125	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OXB_RS02130	COG0039	L-malate dehydrogenase activity
OXB_RS02135	COG1012	belongs to the aldehyde dehydrogenase family
OXB_RS02145	COG0583	DNA-binding transcription factor activity
OXB_RS02150	COG1301	dicarboxylic acid transport
OXB_RS02160	COG2233	PERMEase
OXB_RS02180	COG1012	belongs to the aldehyde dehydrogenase family
OXB_RS02220	COG0450	alkyl hydroperoxide reductase
OXB_RS02240	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OXB_RS02245	COG1522	sequence-specific DNA binding
OXB_RS02250	COG0010	Belongs to the arginase family
OXB_RS02275	COG0668	transmembrane transport
OXB_RS02280	COG0492	ferredoxin-NADP+ reductase activity
OXB_RS02285	COG1120	ATPase activity
OXB_RS02290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OXB_RS02295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OXB_RS02300	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OXB_RS02305	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OXB_RS02320	COG2153	protein acetylation
OXB_RS02325	COG2226	methyltransferase
OXB_RS02335	COG1120	ATPase activity
OXB_RS02340	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OXB_RS02345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OXB_RS02370	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OXB_RS02370	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OXB_RS02380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OXB_RS02390	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OXB_RS02395	COG1266	CAAX protease self-immunity
OXB_RS02400	COG1012	belongs to the aldehyde dehydrogenase family
OXB_RS02420	COG0805	protein transport
OXB_RS02425	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OXB_RS02435	COG0488	(ABC) transporter
OXB_RS02440	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OXB_RS02445	COG0456	acetyltransferase
OXB_RS02450	COG1214	PFAM Peptidase M22, glycoprotease
OXB_RS02455	COG0802	atpase or kinase
OXB_RS02520	COG3091	SprT-like family
OXB_RS02525	COG2183	response to ionizing radiation
OXB_RS02530	COG2208	phosphoserine phosphatase activity
OXB_RS02535	COG1191	sigma factor activity
OXB_RS02540	COG2172	sigma factor antagonist activity
OXB_RS02550	COG2208	phosphoserine phosphatase activity
OXB_RS02555	COG2172	sigma factor antagonist activity
OXB_RS02560	COG1366	Belongs to the anti-sigma-factor antagonist family
OXB_RS02565	COG1366	Belongs to the anti-sigma-factor antagonist family
OXB_RS02570	COG2337	Toxic component of a toxin-antitoxin (TA) module
OXB_RS02585	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
OXB_RS02590	COG0736	holo-[acyl-carrier-protein] synthase activity
OXB_RS02595	COG0705	Rhomboid family
OXB_RS02600	COG3428	Bacterial PH domain
OXB_RS02605	COG3402	PFAM membrane-flanked domain
OXB_RS02610	COG0513	Belongs to the DEAD box helicase family
OXB_RS02620	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OXB_RS02625	COG1181	Belongs to the D-alanine--D-alanine ligase family
OXB_RS02630	COG0772	Belongs to the SEDS family
OXB_RS02635	COG0772	Belongs to the SEDS family
OXB_RS02645	COG2814	Major facilitator Superfamily
OXB_RS02650	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OXB_RS02685	COG0346	lactoylglutathione lyase activity
OXB_RS02695	COG2996	Protein conserved in bacteria
OXB_RS02720	COG0589	response to stress
OXB_RS02725	COG1320	monovalent cation:proton antiporter activity
OXB_RS02730	COG2212	antiporter activity
OXB_RS02735	COG1863	multisubunit Na H antiporter MnhE subunit
OXB_RS02740	COG0651	ATP synthesis coupled electron transport
OXB_RS02745	COG1006	Multisubunit Na H antiporter MnhC subunit
OXB_RS02750	COG2111	Na H antiporter
OXB_RS02755	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OXB_RS02755	COG2111	Na H antiporter
OXB_RS02765	COG0812	UDP-N-acetylmuramate dehydrogenase activity
OXB_RS02775	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OXB_RS02780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OXB_RS02780	COG0723	plastoquinol--plastocyanin reductase activity
OXB_RS02785	COG1227	inorganic diphosphatase activity
OXB_RS02790	COG1959	2 iron, 2 sulfur cluster binding
OXB_RS02805	COG0693	protein deglycase activity
OXB_RS02815	COG1132	(ABC) transporter
OXB_RS02825	COG0477	Major facilitator Superfamily
OXB_RS02840	COG4607	ABC-type enterochelin transport system periplasmic component
OXB_RS02845	COG4604	ABC transporter, ATP-binding protein
OXB_RS02850	COG4605	iron ion homeostasis
OXB_RS02855	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OXB_RS02865	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OXB_RS02885	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OXB_RS02890	COG0590	tRNA wobble adenosine to inosine editing
OXB_RS02895	COG4876	unkown
OXB_RS02900	COG0318	PFAM AMP-dependent synthetase and ligase
OXB_RS02915	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OXB_RS02920	COG1116	anion transmembrane transporter activity
OXB_RS02935	COG2824	Alkylphosphonate utilization operon protein PhnA
OXB_RS02940	COG1595	DNA-templated transcription, initiation
OXB_RS02970	COG1595	DNA-templated transcription, initiation
OXB_RS02990	COG2814	Major facilitator Superfamily
OXB_RS02995	COG2268	Band 7 protein
OXB_RS03000	COG1585	Membrane protein implicated in regulation of membrane protease activity
OXB_RS03005	COG1392	Phosphate transport regulator
OXB_RS03010	COG0306	phosphate transporter
OXB_RS03015	COG1278	Cold shock
OXB_RS03030	COG0500	methyltransferase
OXB_RS03040	COG1063	alcohol dehydrogenase
OXB_RS03045	COG2032	superoxide dismutase activity
OXB_RS03065	COG0456	acetyltransferase
OXB_RS03105	COG1131	(ABC) transporter
OXB_RS03125	COG1279	arginine transmembrane transporter activity
OXB_RS03130	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OXB_RS03135	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
OXB_RS03135	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
OXB_RS03145	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OXB_RS03155	COG1028	Short-chain dehydrogenase reductase Sdr
OXB_RS03160	COG0473	3-isopropylmalate dehydrogenase activity
OXB_RS03175	COG1024	Enoyl-CoA hydratase
OXB_RS03180	COG0183	Belongs to the thiolase family
OXB_RS03185	COG0318	PFAM AMP-dependent synthetase and ligase
OXB_RS03190	COG1309	transcriptional regulator
OXB_RS03195	COG1250	3-hydroxyacyl-CoA dehydrogenase
OXB_RS03200	COG1960	acyl-CoA dehydrogenase activity
OXB_RS03205	COG0318	PFAM AMP-dependent synthetase and ligase
OXB_RS03235	COG0789	Transcriptional regulator
OXB_RS03255	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OXB_RS03260	COG0393	Putative heavy-metal-binding
OXB_RS03265	COG1966	Carbon starvation protein
OXB_RS03275	COG3275	phosphorelay sensor kinase activity
OXB_RS03280	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OXB_RS03290	COG4895	conserved protein (DUF2196)
OXB_RS03300	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OXB_RS03305	COG0573	inorganic phosphate transmembrane transporter activity
OXB_RS03310	COG0581	inorganic phosphate transmembrane transporter activity
OXB_RS03315	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OXB_RS03320	COG5002	protein histidine kinase activity
OXB_RS03350	COG4856	YbbR-like protein
OXB_RS03355	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OXB_RS03360	COG5662	AntiSigma factor
OXB_RS03365	COG1595	DNA-templated transcription, initiation
OXB_RS03375	COG5001	Diguanylate cyclase
OXB_RS03435	COG2194	sulfuric ester hydrolase activity
OXB_RS03445	COG0489	protein tyrosine kinase activity
OXB_RS03450	COG0860	N-Acetylmuramoyl-L-alanine amidase
OXB_RS03460	COG0662	Cupin 2, conserved barrel domain protein
OXB_RS03470	COG1304	FMN binding
OXB_RS03480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OXB_RS03485	COG0702	epimerase
OXB_RS03505	COG5504	Zn-dependent protease
OXB_RS03515	COG1802	Transcriptional regulator
OXB_RS03525	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OXB_RS03530	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
OXB_RS03535	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
OXB_RS03535	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
OXB_RS03540	COG0277	FAD linked oxidase domain protein
OXB_RS03550	COG0542	response to heat
OXB_RS03560	COG2304	oxidoreductase activity
OXB_RS03565	COG2318	DinB family
OXB_RS03580	COG1131	(ABC) transporter
OXB_RS03585	COG1725	Transcriptional regulator
OXB_RS03590	COG1115	amino acid carrier protein
OXB_RS03610	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OXB_RS03615	COG0101	tRNA pseudouridine synthase activity
OXB_RS03620	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OXB_RS03625	COG1122	ATPase activity
OXB_RS03630	COG1122	ATPase activity
OXB_RS03640	COG0202	RNA polymerase activity
OXB_RS03655	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OXB_RS03665	COG0201	protein transport
OXB_RS03685	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OXB_RS03690	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OXB_RS03715	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OXB_RS03720	COG0255	Belongs to the universal ribosomal protein uL29 family
OXB_RS03725	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OXB_RS03730	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OXB_RS03745	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OXB_RS03760	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OXB_RS03785	COG0049	tRNA binding
OXB_RS03795	COG1358	cellular component organization or biogenesis
OXB_RS03810	COG2813	Specifically methylates the guanine in position
OXB_RS03815	COG0222	ribosome binding
OXB_RS03835	COG0250	Participates in transcription elongation, termination and antitermination
OXB_RS03840	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
OXB_RS03850	COG3688	RNA-binding protein containing a PIN domain
OXB_RS03855	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OXB_RS03870	COG1045	serine acetyltransferase
OXB_RS03890	COG4956	integral membrane protein (PIN domain superfamily)
OXB_RS03895	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
OXB_RS03900	COG0542	response to heat
OXB_RS03905	COG3869	Catalyzes the specific phosphorylation of arginine residues in
OXB_RS03910	COG3880	PFAM UvrB UvrC protein
OXB_RS03930	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OXB_RS03935	COG1268	BioY protein
OXB_RS03945	COG0646	methionine synthase
OXB_RS03945	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
OXB_RS03950	COG0646	methionine synthase
OXB_RS03950	COG1410	methionine synthase
OXB_RS03960	COG0415	Belongs to the DNA photolyase family
OXB_RS03975	COG3011	Protein conserved in bacteria
OXB_RS03985	COG1012	belongs to the aldehyde dehydrogenase family
OXB_RS03990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OXB_RS03995	COG0745	RESPONSE REGULATOR receiver
OXB_RS04000	COG5002	protein histidine kinase activity
OXB_RS04000	COG3850	Histidine kinase
OXB_RS04005	COG3226	Transcriptional regulator
OXB_RS04015	COG0655	NAD(P)H dehydrogenase (quinone) activity
OXB_RS04020	COG0400	carboxylic ester hydrolase activity
OXB_RS04030	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
OXB_RS04035	COG0351	phosphomethylpyrimidine kinase
OXB_RS04040	COG0352	thiamine-phosphate diphosphorylase activity
OXB_RS04095	COG2197	response regulator
OXB_RS04100	COG4585	Histidine kinase
OXB_RS04105	COG3239	Fatty acid desaturase
OXB_RS04110	COG1028	Short-chain dehydrogenase reductase Sdr
OXB_RS04115	COG3118	belongs to the thioredoxin family
OXB_RS04120	COG0671	phosphoesterase, PA-phosphatase related
OXB_RS04130	COG1970	mechanosensitive ion channel activity
OXB_RS04150	COG0390	transport system, permease component
OXB_RS04155	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OXB_RS04160	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
OXB_RS04165	COG1131	(ABC) transporter
OXB_RS04170	COG1131	(ABC) transporter
OXB_RS04175	COG1725	Transcriptional regulator
OXB_RS04200	COG4372	Transposase
OXB_RS04220	COG0697	spore germination
OXB_RS04235	COG0840	transmembrane signaling receptor activity
OXB_RS04240	COG1607	acyl-coa hydrolase
OXB_RS04245	COG0791	NLP P60 protein
OXB_RS04250	COG4948	Mandelate Racemase Muconate Lactonizing
OXB_RS04255	COG1619	proteins homologs of microcin C7 resistance protein MccF
OXB_RS04270	COG2746	aminoglycoside 3-N-acetyltransferase activity
OXB_RS04275	COG0159	tryptophan synthase activity
OXB_RS04280	COG0133	tryptophan synthase activity
OXB_RS04285	COG0135	phosphoribosylanthranilate isomerase activity
OXB_RS04290	COG0134	indole-3-glycerol-phosphate synthase activity
OXB_RS04295	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OXB_RS04300	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OXB_RS04305	COG2508	Transcriptional regulator
OXB_RS04320	COG1473	amidohydrolase
OXB_RS04325	COG1187	pseudouridine synthase activity
OXB_RS04330	COG2239	Acts as a magnesium transporter
OXB_RS04335	COG0702	epimerase
OXB_RS04340	COG0427	acetyl-CoA hydrolase
OXB_RS04350	COG2270	Major facilitator Superfamily
OXB_RS04355	COG0183	Belongs to the thiolase family
OXB_RS04360	COG1960	acyl-CoA dehydrogenase activity
OXB_RS04370	COG0318	PFAM AMP-dependent synthetase and ligase
OXB_RS04375	COG1024	Enoyl-CoA hydratase
OXB_RS04380	COG1250	3-hydroxyacyl-CoA dehydrogenase
OXB_RS04385	COG2508	Transcriptional regulator
OXB_RS04390	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OXB_RS04400	COG0179	Fumarylacetoacetate (FAA) hydrolase
OXB_RS04410	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
OXB_RS04415	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
OXB_RS04415	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
OXB_RS04420	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OXB_RS04425	COG2211	Major facilitator Superfamily
OXB_RS04430	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
OXB_RS04440	COG1414	Transcriptional regulator
OXB_RS04450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OXB_RS04495	COG2814	Major facilitator Superfamily
OXB_RS04505	COG2514	catechol 2,3-dioxygenase activity
OXB_RS04510	COG1733	regulation of RNA biosynthetic process
OXB_RS04530	COG1012	belongs to the aldehyde dehydrogenase family
OXB_RS04540	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
OXB_RS04540	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
OXB_RS04550	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OXB_RS04560	COG0247	lactate metabolic process
OXB_RS04565	COG0277	FAD linked oxidase domain protein
OXB_RS04570	COG2186	Transcriptional regulator
OXB_RS04580	COG2233	PERMEase
OXB_RS04585	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OXB_RS04600	COG0583	DNA-binding transcription factor activity
OXB_RS04610	COG2304	oxidoreductase activity
OXB_RS04615	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
OXB_RS04630	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
OXB_RS04635	COG1533	DNA photolyase activity
OXB_RS04645	COG1473	amidohydrolase
OXB_RS04655	COG2011	ABC-type metal ion transport system permease component
OXB_RS04660	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OXB_RS04675	COG0154	amidase activity
OXB_RS04685	COG0579	oxidoreductase
OXB_RS04710	COG3290	protein histidine kinase activity
OXB_RS04715	COG4565	transcriptional regulatory protein
OXB_RS04720	COG2851	Citrate transporter
OXB_RS04730	COG1114	Component of the transport system for branched-chain amino acids
OXB_RS04735	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OXB_RS04745	COG0300	oxidoreductase activity
OXB_RS04775	COG0322	excinuclease ABC activity
OXB_RS04800	COG4372	Transposase
OXB_RS04830	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
OXB_RS04875	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OXB_RS04890	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
OXB_RS04895	COG4853	Protein conserved in bacteria
OXB_RS04900	COG4863	YycH protein
OXB_RS04905	COG5002	protein histidine kinase activity
OXB_RS04910	COG0745	RESPONSE REGULATOR receiver
OXB_RS04915	COG1196	nuclear chromosome segregation
OXB_RS04915	COG0741	lytic transglycosylase activity
OXB_RS04915	COG0739	heme binding
OXB_RS04920	COG0305	Participates in initiation and elongation during chromosome replication
OXB_RS04930	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
OXB_RS04940	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OXB_RS04945	COG0629	single-stranded DNA binding
OXB_RS04960	COG0012	GTP binding
OXB_RS04965	COG4481	Protein conserved in bacteria
OXB_RS04970	COG0668	transmembrane transport
OXB_RS04980	COG1811	Na channel or pump
OXB_RS04985	COG1475	DNA binding
OXB_RS04990	COG1192	Involved in chromosome partitioning
OXB_RS05015	COG1847	R3H domain protein
OXB_RS05020	COG0706	membrane insertase activity
OXB_RS05025	COG0594	ribonuclease P activity
OXB_RS05035	COG0592	DNA-directed DNA polymerase activity
OXB_RS05050	COG0187	DNA topoisomerase II activity
OXB_RS05055	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OXB_RS05095	COG0516	GMP reductase activity
OXB_RS05095	COG0517	IMP dehydrogenase activity
OXB_RS05105	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OXB_RS05110	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
OXB_RS05115	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OXB_RS05120	COG0590	tRNA wobble adenosine to inosine editing
OXB_RS05125	COG1428	Deoxynucleoside kinase
OXB_RS05130	COG1428	Deoxynucleoside kinase
OXB_RS05135	COG0527	aspartate kinase activity
OXB_RS05140	COG0460	homoserine dehydrogenase
OXB_RS05145	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OXB_RS05165	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OXB_RS05170	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OXB_RS05220	COG1982	Orn Lys Arg decarboxylase major
OXB_RS05225	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OXB_RS05230	COG3870	Protein conserved in bacteria
OXB_RS05235	COG1728	Protein conserved in bacteria
OXB_RS05240	COG0470	DNA polymerase III
OXB_RS05245	COG1774	PSP1 C-terminal conserved region
OXB_RS05250	COG4467	Involved in initiation control of chromosome replication
OXB_RS05255	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
OXB_RS05265	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OXB_RS05270	COG2002	toxin-antitoxin pair type II binding
OXB_RS05280	COG0084	hydrolase, TatD family'
OXB_RS05285	COG3583	domain protein
OXB_RS05285	COG3584	3D domain protein
OXB_RS05300	COG4466	Protein conserved in bacteria
OXB_RS05310	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OXB_RS05315	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OXB_RS05320	COG0251	oxidation-reduction process
OXB_RS05330	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OXB_RS05345	COG0193	aminoacyl-tRNA hydrolase activity
OXB_RS05355	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OXB_RS05360	COG2002	toxin-antitoxin pair type II binding
OXB_RS05365	COG2244	polysaccharide biosynthetic process
OXB_RS05370	COG3956	TIGRFAM MazG family protein
OXB_RS05375	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
OXB_RS05395	COG1098	S1 RNA binding domain
OXB_RS05405	COG2208	phosphoserine phosphatase activity
OXB_RS05410	COG0037	tRNA processing
OXB_RS05410	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
OXB_RS05415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
OXB_RS05420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OXB_RS05425	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
OXB_RS05435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OXB_RS05440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OXB_RS05445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OXB_RS05450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OXB_RS05455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OXB_RS05460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OXB_RS05465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OXB_RS05560	COG1295	ribonuclease BN
OXB_RS05570	COG3850	Histidine kinase
OXB_RS05570	COG5002	protein histidine kinase activity
OXB_RS05600	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OXB_RS05625	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
OXB_RS05630	COG4841	protein insertion into membrane
OXB_RS05675	COG4149	molybdate abc transporter
OXB_RS05680	COG0725	ABC transporter, periplasmic molybdate-binding protein
OXB_RS05685	COG3842	ATPase activity
OXB_RS05690	COG4841	protein insertion into membrane
OXB_RS05700	COG0697	spore germination
OXB_RS05705	COG4682	membrane
OXB_RS05710	COG2112	serine threonine protein kinase
OXB_RS05715	COG2217	Heavy metal translocating P-type atpase
OXB_RS05720	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
OXB_RS05725	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OXB_RS05760	COG0640	Transcriptional regulator
OXB_RS05770	COG1937	Protein conserved in bacteria
OXB_RS05775	COG2608	mercury ion transmembrane transporter activity
OXB_RS05780	COG2217	Heavy metal translocating P-type atpase
OXB_RS05795	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
OXB_RS05800	COG2814	Major facilitator Superfamily
OXB_RS05825	COG2972	Histidine kinase
OXB_RS05825	COG0745	RESPONSE REGULATOR receiver
OXB_RS05830	COG3300	MHYT domain
OXB_RS05830	COG5001	Diguanylate cyclase
OXB_RS05835	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
OXB_RS05845	COG5298	Protein conserved in bacteria
OXB_RS05850	COG1215	transferase activity, transferring glycosyl groups
OXB_RS05865	COG1595	DNA-templated transcription, initiation
OXB_RS05875	COG0277	FAD linked oxidase domain protein
OXB_RS05895	COG0559	Belongs to the binding-protein-dependent transport system permease family
OXB_RS05915	COG0697	spore germination
OXB_RS05925	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OXB_RS05945	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OXB_RS05960	COG2814	Major facilitator Superfamily
OXB_RS05970	COG1346	cytolysis
OXB_RS05975	COG1380	Effector of murein hydrolase LrgA
OXB_RS05980	COG0628	permease
OXB_RS05985	COG1309	transcriptional regulator
OXB_RS06020	COG0427	acetyl-CoA hydrolase
OXB_RS06025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OXB_RS06030	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OXB_RS06040	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OXB_RS06060	COG1960	acyl-CoA dehydrogenase activity
OXB_RS06065	COG1960	acyl-CoA dehydrogenase activity
OXB_RS06070	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
OXB_RS06075	COG0318	PFAM AMP-dependent synthetase and ligase
OXB_RS06080	COG1028	Short-chain dehydrogenase reductase Sdr
OXB_RS06085	COG1028	Short-chain dehydrogenase reductase Sdr
OXB_RS06090	COG1960	acyl-CoA dehydrogenase activity
OXB_RS06095	COG1250	3-hydroxyacyl-CoA dehydrogenase
OXB_RS06100	COG1024	Enoyl-CoA hydratase
OXB_RS06105	COG0697	spore germination
OXB_RS06110	COG2195	Cleaves the N-terminal amino acid of tripeptides
OXB_RS06115	COG0583	DNA-binding transcription factor activity
OXB_RS06120	COG2855	membrane
OXB_RS06130	COG1937	Protein conserved in bacteria
OXB_RS06135	COG2210	Belongs to the sulfur carrier protein TusA family
OXB_RS06145	COG0425	Belongs to the sulfur carrier protein TusA family
OXB_RS06145	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OXB_RS06150	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OXB_RS06150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OXB_RS06155	COG0425	Belongs to the sulfur carrier protein TusA family
OXB_RS06160	COG0730	response to heat
OXB_RS06165	COG2814	Major facilitator Superfamily
OXB_RS06170	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
OXB_RS06180	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
OXB_RS06215	COG0492	ferredoxin-NADP+ reductase activity
OXB_RS06220	COG1141	Ferredoxin
OXB_RS06225	COG3396	Phenylacetate-CoA oxygenase
OXB_RS06255	COG1024	Enoyl-CoA hydratase
OXB_RS06260	COG1012	belongs to the aldehyde dehydrogenase family
OXB_RS06265	COG1250	3-hydroxyacyl-CoA dehydrogenase
OXB_RS06270	COG0183	Belongs to the thiolase family
OXB_RS06275	COG1024	Enoyl-CoA hydratase
OXB_RS06280	COG3327	negative regulation of DNA-templated transcription, initiation
OXB_RS06295	COG0840	transmembrane signaling receptor activity
OXB_RS06300	COG0386	Belongs to the glutathione peroxidase family
OXB_RS06305	COG0166	Belongs to the GPI family
OXB_RS06315	COG2258	MOSC domain
OXB_RS06320	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OXB_RS06325	COG0431	NADPH-dependent FMN reductase
OXB_RS06330	COG0697	spore germination
OXB_RS06355	COG2205	protein histidine kinase activity
OXB_RS06355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OXB_RS06355	COG2198	Histidine kinase
OXB_RS06355	COG0784	Response regulator, receiver
OXB_RS06400	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
OXB_RS06425	COG1120	ATPase activity
OXB_RS06430	COG4139	cobalamin transport
OXB_RS06445	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OXB_RS06450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OXB_RS06455	COG1120	ATPase activity
OXB_RS06460	COG0357	Ribosomal RNA small subunit methyltransferase G
OXB_RS06470	COG2234	aminopeptidase activity
OXB_RS06475	COG2197	response regulator
OXB_RS06500	COG0183	Belongs to the thiolase family
OXB_RS06515	COG0318	PFAM AMP-dependent synthetase and ligase
OXB_RS06525	COG0586	Pfam SNARE associated Golgi protein
OXB_RS06530	COG1968	undecaprenyl-diphosphatase activity
OXB_RS06535	COG1234	tRNA 3'-trailer cleavage
OXB_RS06545	COG0745	RESPONSE REGULATOR receiver
OXB_RS06550	COG5002	protein histidine kinase activity
OXB_RS06550	COG3850	Histidine kinase
OXB_RS06560	COG0840	transmembrane signaling receptor activity
OXB_RS06580	COG3279	Response regulator of the LytR AlgR family
OXB_RS06585	COG1732	Glycine betaine
OXB_RS06590	COG1174	glycine betaine transport
OXB_RS06595	COG1125	glycine betaine transport
OXB_RS06595	COG0517	IMP dehydrogenase activity
OXB_RS06600	COG0745	RESPONSE REGULATOR receiver
OXB_RS06605	COG2205	protein histidine kinase activity
OXB_RS06610	COG1136	(ABC) transporter
OXB_RS06615	COG0577	efflux transmembrane transporter activity
OXB_RS06625	COG1573	uracil-dna glycosylase
OXB_RS06640	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OXB_RS06645	COG1140	nitrate reductase beta subunit
OXB_RS06655	COG2181	nitrate reductase activity
OXB_RS06665	COG4585	Histidine kinase
OXB_RS06670	COG2197	response regulator
OXB_RS06680	COG2223	nitrite transmembrane transporter activity
OXB_RS06685	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OXB_RS06695	COG0315	cyclic pyranopterin monophosphate synthase activity
OXB_RS06710	COG0314	molybdopterin synthase activity
OXB_RS06720	COG0746	molybdenum cofactor guanylyltransferase activity
OXB_RS06725	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OXB_RS06740	COG3192	ethanolamine utilization protein
OXB_RS06745	COG4810	utilization protein
OXB_RS06750	COG4917	ethanolamine utilization protein
OXB_RS06755	COG4819	ethanolamine utilization protein
OXB_RS06760	COG4303	Ethanolamine ammonia lyase large subunit
OXB_RS06765	COG4302	ethanolamine ammonia-lyase activity
OXB_RS06775	COG1454	alcohol dehydrogenase
OXB_RS06775	COG1012	belongs to the aldehyde dehydrogenase family
OXB_RS06790	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
OXB_RS06795	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
OXB_RS06800	COG0039	L-malate dehydrogenase activity
OXB_RS06820	COG3012	SEC-C Motif Domain Protein
OXB_RS06820	COG1405	negative regulation of cell septum assembly
OXB_RS06835	COG1309	transcriptional regulator
OXB_RS06840	COG2814	Major facilitator Superfamily
OXB_RS06845	COG3012	SEC-C Motif Domain Protein
OXB_RS06845	COG1405	negative regulation of cell septum assembly
OXB_RS06850	COG1012	belongs to the aldehyde dehydrogenase family
OXB_RS06860	COG1960	acyl-CoA dehydrogenase activity
OXB_RS06865	COG0583	DNA-binding transcription factor activity
OXB_RS06885	COG1914	H( )-stimulated, divalent metal cation uptake system
OXB_RS06895	COG0010	Belongs to the arginase family
OXB_RS06900	COG0436	Aminotransferase
OXB_RS06905	COG1309	transcriptional regulator
OXB_RS06910	COG1511	domain protein
OXB_RS06915	COG1028	Short-chain dehydrogenase reductase Sdr
OXB_RS06920	COG0471	metal ion transport
OXB_RS06930	COG2966	Psort location CytoplasmicMembrane, score
OXB_RS06935	COG3610	response to peptide
OXB_RS06940	COG2199	diguanylate cyclase activity
OXB_RS06940	COG2200	EAL domain
OXB_RS06940	COG2202	Pas domain
OXB_RS06945	COG0697	spore germination
OXB_RS06960	COG1131	(ABC) transporter
OXB_RS06965	COG1725	Transcriptional regulator
OXB_RS06970	COG1132	(ABC) transporter
OXB_RS06975	COG1132	(ABC) transporter
OXB_RS07000	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
OXB_RS07015	COG1307	EDD domain protein, DegV family
OXB_RS07025	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OXB_RS07030	COG4536	flavin adenine dinucleotide binding
OXB_RS07060	COG0431	NADPH-dependent FMN reductase
OXB_RS07065	COG0551	DNA topoisomerase type I activity
OXB_RS07065	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OXB_RS07075	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OXB_RS07080	COG2364	Membrane
OXB_RS07090	COG3314	Sporulation integral membrane protein YlbJ
OXB_RS07100	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OXB_RS07120	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OXB_RS07130	COG2363	Small membrane protein
OXB_RS07145	COG3253	May function as heme-dependent peroxidase
OXB_RS07150	COG0280	phosphate acetyltransferase
OXB_RS07165	COG1078	dGTPase activity
OXB_RS07170	COG3465	dGTPase activity
OXB_RS07190	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OXB_RS07210	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
OXB_RS07220	COG1492	cobalamin metabolic process
OXB_RS07225	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
OXB_RS07240	COG2096	Adenosyltransferase
OXB_RS07245	COG0247	lactate metabolic process
OXB_RS07245	COG2181	nitrate reductase activity
OXB_RS07250	COG0183	Belongs to the thiolase family
OXB_RS07255	COG1250	3-hydroxyacyl-CoA dehydrogenase
OXB_RS07260	COG1960	acyl-CoA dehydrogenase activity
OXB_RS07265	COG1960	acyl-CoA dehydrogenase activity
OXB_RS07270	COG3226	Transcriptional regulator
OXB_RS07275	COG1703	isobutyryl-CoA mutase activity
OXB_RS07275	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OXB_RS07275	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OXB_RS07290	COG0504	CTP synthase activity
OXB_RS07300	COG4821	SIS domain
OXB_RS07305	COG4585	Histidine kinase
OXB_RS07310	COG2197	response regulator
OXB_RS07315	COG2204	response regulator
OXB_RS07320	COG0191	fructose-bisphosphate aldolase activity
OXB_RS07330	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OXB_RS07335	COG1494	fructose-1,6-bisphosphatase
OXB_RS07340	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
OXB_RS07345	COG0254	rRNA binding
OXB_RS07350	COG1435	thymidine kinase activity
OXB_RS07355	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OXB_RS07370	COG0009	L-threonylcarbamoyladenylate synthase
OXB_RS07385	COG0840	transmembrane signaling receptor activity
OXB_RS07390	COG0698	ribose 5-phosphate isomerase
OXB_RS07395	COG4475	Protein of unknown function (DUF436)
OXB_RS07410	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OXB_RS07415	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
OXB_RS07430	COG0356	it plays a direct role in the translocation of protons across the membrane
OXB_RS07435	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OXB_RS07445	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OXB_RS07460	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OXB_RS07465	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OXB_RS07475	COG4836	Membrane
OXB_RS07495	COG2385	sporulation resulting in formation of a cellular spore
OXB_RS07505	COG1609	Transcriptional regulator
OXB_RS07510	COG1077	Cell shape determining protein MreB Mrl
OXB_RS07515	COG4786	Flagellar basal body rod
OXB_RS07520	COG4786	Flagellar basal body rod
OXB_RS07560	COG0629	single-stranded DNA binding
OXB_RS07565	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OXB_RS07575	COG1396	sequence-specific DNA binding
OXB_RS07615	COG2076	Multidrug Resistance protein
OXB_RS07640	COG3409	Peptidoglycan-binding domain 1 protein
OXB_RS07640	COG0793	Belongs to the peptidase S41A family
OXB_RS07740	COG4372	Transposase
OXB_RS07750	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
OXB_RS07755	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OXB_RS07765	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OXB_RS07770	COG1228	amidohydrolase
OXB_RS07780	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OXB_RS07790	COG1309	transcriptional regulator
OXB_RS07795	COG1309	transcriptional regulator
OXB_RS07810	COG2267	carboxylic ester hydrolase activity
OXB_RS07820	COG0747	negative chemotaxis
OXB_RS07825	COG0606	chelatase, subunit chli
OXB_RS07835	COG3275	phosphorelay sensor kinase activity
OXB_RS07840	COG4753	response regulator
OXB_RS07840	COG2207	Transcriptional regulator
OXB_RS07850	COG0601	transmembrane transport
OXB_RS07855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OXB_RS07860	COG0444	Belongs to the ABC transporter superfamily
OXB_RS07865	COG4608	Belongs to the ABC transporter superfamily
OXB_RS07930	COG2113	Glycine betaine
OXB_RS07940	COG2358	TRAP transporter, solute receptor (TAXI family
OXB_RS07955	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OXB_RS07960	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OXB_RS07970	COG1228	amidohydrolase
OXB_RS07980	COG0601	transmembrane transport
OXB_RS07985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OXB_RS07990	COG0444	Belongs to the ABC transporter superfamily
OXB_RS07995	COG4608	Belongs to the ABC transporter superfamily
OXB_RS08020	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OXB_RS08025	COG1733	regulation of RNA biosynthetic process
OXB_RS08065	COG0069	glutamate synthase activity
OXB_RS08075	COG1953	Uracil, thiamine, allantoin
OXB_RS08085	COG0788	formyltetrahydrofolate deformylase activity
OXB_RS08095	COG0840	transmembrane signaling receptor activity
OXB_RS08100	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
OXB_RS08110	COG1120	ATPase activity
OXB_RS08115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OXB_RS08120	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OXB_RS08145	COG5263	repeat protein
OXB_RS08145	COG4193	domain, Protein
OXB_RS08165	COG0793	Belongs to the peptidase S41A family
OXB_RS08165	COG3409	Peptidoglycan-binding domain 1 protein
OXB_RS08190	COG0726	polysaccharide deacetylase
OXB_RS08200	COG0196	riboflavin kinase activity
OXB_RS08205	COG2189	Belongs to the N(4) N(6)-methyltransferase family
OXB_RS08220	COG1473	amidohydrolase
OXB_RS08230	COG4948	Mandelate Racemase Muconate Lactonizing
OXB_RS08235	COG1737	Transcriptional regulator
OXB_RS08245	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OXB_RS08260	COG3949	Membrane
OXB_RS08275	COG0129	dihydroxy-acid dehydratase activity
OXB_RS08280	COG0028	Belongs to the TPP enzyme family
OXB_RS08285	COG0440	acetolactate synthase activity
OXB_RS08310	COG0066	3-isopropylmalate dehydratase activity
OXB_RS08330	COG1361	Conserved repeat domain
OXB_RS08360	COG3279	Response regulator of the LytR AlgR family
OXB_RS08365	COG2224	Isocitrate lyase
OXB_RS08380	COG0791	NLP P60 protein
OXB_RS08385	COG0438	transferase activity, transferring glycosyl groups
OXB_RS08385	COG0297	glycogen (starch) synthase activity
OXB_RS08395	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OXB_RS08400	COG0659	secondary active sulfate transmembrane transporter activity
OXB_RS08405	COG1388	LysM domain
OXB_RS08405	COG0791	NLP P60 protein
OXB_RS08410	COG1114	Component of the transport system for branched-chain amino acids
OXB_RS08415	COG1716	ATPase activity
OXB_RS08415	COG5001	Diguanylate cyclase
OXB_RS08420	COG0281	malic enzyme
OXB_RS08425	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OXB_RS08430	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OXB_RS08435	COG0363	glucosamine-6-phosphate deaminase activity
OXB_RS08445	COG0791	NLP P60 protein
OXB_RS08455	COG0653	protein targeting
OXB_RS08460	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OXB_RS08465	COG1316	TRANSCRIPTIONal
OXB_RS08470	COG1739	Uncharacterized protein family UPF0029
OXB_RS08475	COG4585	Histidine kinase
OXB_RS08480	COG2197	response regulator
OXB_RS08500	COG1473	amidohydrolase
OXB_RS08505	COG2329	Antibiotic biosynthesis monooxygenase
OXB_RS08510	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OXB_RS08515	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
OXB_RS08520	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
OXB_RS08530	COG0584	glycerophosphoryl diester phosphodiesterase
OXB_RS08535	COG0095	Lipoate-protein ligase
OXB_RS08540	COG0745	RESPONSE REGULATOR receiver
OXB_RS08545	COG2205	protein histidine kinase activity
OXB_RS08550	COG1136	(ABC) transporter
OXB_RS08555	COG0577	efflux transmembrane transporter activity
OXB_RS08565	COG0318	PFAM AMP-dependent synthetase and ligase
OXB_RS08580	COG1131	(ABC) transporter
OXB_RS08605	COG0823	Involved in the tonB-independent uptake of proteins
OXB_RS08605	COG1506	peptidase
OXB_RS08605	COG4946	Tricorn protease homolog
OXB_RS08620	COG1131	(ABC) transporter
OXB_RS08625	COG1511	domain protein
OXB_RS08625	COG0842	Transport permease protein
OXB_RS08630	COG1309	transcriptional regulator
OXB_RS08635	COG1027	Aspartate ammonia-lyase
OXB_RS08645	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OXB_RS08655	COG1024	Enoyl-CoA hydratase
OXB_RS08660	COG1307	EDD domain protein, DegV family
OXB_RS08665	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
OXB_RS08685	COG2747	anti-sigma28 factor FlgM
OXB_RS08690	COG3418	PFAM FlgN family protein
OXB_RS08695	COG4786	Flagellar basal body rod
OXB_RS08695	COG1256	bacterial-type flagellum assembly
OXB_RS08700	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OXB_RS08720	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
OXB_RS08725	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
OXB_RS08730	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OXB_RS08735	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OXB_RS08790	COG0179	Fumarylacetoacetate (FAA) hydrolase
OXB_RS08795	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
OXB_RS08865	COG1610	YqeY-like protein
OXB_RS08885	COG0840	transmembrane signaling receptor activity
OXB_RS08895	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
OXB_RS08900	COG1516	flagellar protein fliS
OXB_RS08925	COG0653	protein targeting
OXB_RS08930	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
OXB_RS08945	COG2010	Cytochrome c
OXB_RS08955	COG2884	Cell division ATP-binding protein ftsE
OXB_RS08960	COG2177	Part of the ABC transporter FtsEX involved in
OXB_RS08965	COG0739	heme binding
OXB_RS08975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OXB_RS08980	COG0793	Belongs to the peptidase S41A family
OXB_RS08980	COG3409	Peptidoglycan-binding domain 1 protein
OXB_RS08985	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OXB_RS08995	COG1028	Short-chain dehydrogenase reductase Sdr
OXB_RS09000	COG1349	DNA-binding transcription factor activity
OXB_RS09005	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OXB_RS09010	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OXB_RS09015	COG0531	amino acid
OXB_RS09020	COG0546	phosphoglycolate phosphatase activity
OXB_RS09040	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
OXB_RS09045	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
OXB_RS09065	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
OXB_RS09070	COG0398	Pfam SNARE associated Golgi protein
OXB_RS09085	COG1695	Transcriptional regulator
OXB_RS09125	COG2311	Membrane
OXB_RS09130	COG0179	Fumarylacetoacetate (FAA) hydrolase
OXB_RS09140	COG0366	Alpha amylase catalytic
OXB_RS09140	COG1874	Beta-galactosidase
OXB_RS09145	COG0446	pyridine nucleotide-disulphide oxidoreductase
OXB_RS09150	COG1307	EDD domain protein, DegV family
OXB_RS09155	COG0561	phosphatase activity
OXB_RS09160	COG1073	alpha beta
OXB_RS09165	COG2151	metal-sulfur cluster biosynthetic enzyme
OXB_RS09200	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OXB_RS09205	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OXB_RS09210	COG0180	Tryptophanyl-tRNA synthetase
OXB_RS09225	COG4166	transmembrane transport
OXB_RS09230	COG0601	transmembrane transport
OXB_RS09235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OXB_RS09240	COG0444	Belongs to the ABC transporter superfamily
OXB_RS09245	COG4608	Belongs to the ABC transporter superfamily
OXB_RS09255	COG1393	Belongs to the ArsC family
OXB_RS09260	COG4862	establishment of competence for transformation
OXB_RS09270	COG1164	Oligoendopeptidase f
OXB_RS09275	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OXB_RS09280	COG2346	COG2346, Truncated hemoglobins
OXB_RS09295	COG2357	RelA SpoT domain protein
OXB_RS09305	COG0564	pseudouridine synthase activity
OXB_RS09310	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OXB_RS09315	COG2239	Acts as a magnesium transporter
OXB_RS09340	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OXB_RS09370	COG2382	esterase
OXB_RS09375	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
OXB_RS09380	COG1126	abc transporter atp-binding protein
OXB_RS09385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OXB_RS09390	COG0765	amino acid transport
OXB_RS09395	COG0765	amino acid transport
OXB_RS09410	COG1024	Enoyl-CoA hydratase
OXB_RS09435	COG4172	Belongs to the ABC transporter superfamily
OXB_RS09440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OXB_RS09450	COG0477	Major facilitator Superfamily
OXB_RS09455	COG0753	catalase activity
OXB_RS09460	COG1012	belongs to the aldehyde dehydrogenase family
OXB_RS09465	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OXB_RS09470	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OXB_RS09485	COG0861	Integral membrane protein TerC family
OXB_RS09490	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OXB_RS09505	COG1846	Transcriptional regulator
OXB_RS09515	COG4873	Protein conserved in bacteria
OXB_RS09520	COG2084	Dehydrogenase
OXB_RS09530	COG3300	MHYT domain
OXB_RS09530	COG5001	Diguanylate cyclase
OXB_RS09535	COG1028	Short-chain dehydrogenase reductase Sdr
OXB_RS09545	COG0517	IMP dehydrogenase activity
OXB_RS09550	COG0477	Major facilitator Superfamily
OXB_RS09555	COG0583	DNA-binding transcription factor activity
OXB_RS09565	COG1131	(ABC) transporter
OXB_RS09580	COG0714	Associated with various cellular activities
OXB_RS09600	COG2814	Major facilitator Superfamily
OXB_RS09605	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
OXB_RS09610	COG1177	transmembrane transport
OXB_RS09615	COG1176	ABC-type spermidine putrescine transport system, permease component I
OXB_RS09620	COG3842	ATPase activity
OXB_RS09645	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OXB_RS09650	COG0569	domain protein
OXB_RS09665	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OXB_RS09690	COG0022	dehydrogenase e1 component
OXB_RS09695	COG0508	dehydrogenase complex catalyzes the overall conversion of
OXB_RS09720	COG0483	inositol monophosphate 1-phosphatase activity
OXB_RS09730	COG1217	gtp-binding protein TYPA
OXB_RS09740	COG4896	Protein conserved in bacteria
OXB_RS09745	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OXB_RS09755	COG0772	Belongs to the SEDS family
OXB_RS09760	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
OXB_RS09795	COG3336	cytochrome c oxidase
OXB_RS09800	COG2322	membrane
OXB_RS09820	COG0527	aspartate kinase activity
OXB_RS09825	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OXB_RS09830	COG3679	Belongs to the UPF0342 family
OXB_RS09835	COG0584	glycerophosphoryl diester phosphodiesterase
OXB_RS09840	COG4471	UPF0298 protein
OXB_RS09855	COG0742	ribosomal rna small subunit methyltransferase
OXB_RS09860	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OXB_RS09870	COG3480	Lon protease (S16) C-terminal proteolytic domain
OXB_RS09885	COG1024	Enoyl-CoA hydratase
OXB_RS09890	COG0439	Biotin carboxylase
OXB_RS09895	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
OXB_RS09900	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OXB_RS09905	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OXB_RS09920	COG2001	Belongs to the MraZ family
OXB_RS09930	COG4839	cell division protein FtsL
OXB_RS09935	COG0768	penicillin binding
OXB_RS09940	COG0768	penicillin binding
OXB_RS09945	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OXB_RS09950	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OXB_RS09955	COG0772	Belongs to the SEDS family
OXB_RS09960	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OXB_RS09965	COG3879	Bacterial protein of unknown function (DUF881)
OXB_RS09970	COG3879	Bacterial protein of unknown function (DUF881)
OXB_RS09975	COG3856	small basic protein
OXB_RS09980	COG0849	cell division
OXB_RS09985	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OXB_RS09995	COG1191	sigma factor activity
OXB_RS10000	COG1191	sigma factor activity
OXB_RS10010	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OXB_RS10020	COG0762	integral membrane protein
OXB_RS10025	COG2302	S4 RNA-binding domain
OXB_RS10030	COG3599	regulation of cell shape
OXB_RS10040	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OXB_RS10045	COG0564	pseudouridine synthase activity
OXB_RS10050	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
OXB_RS10060	COG0540	Belongs to the ATCase OTCase family
OXB_RS10070	COG0505	Belongs to the CarA family
OXB_RS10085	COG0167	dihydroorotate dehydrogenase activity
OXB_RS10120	COG0194	GDP metabolic process
OXB_RS10130	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OXB_RS10135	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OXB_RS10140	COG0242	peptide deformylase activity
OXB_RS10150	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OXB_RS10150	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OXB_RS10155	COG0631	protein serine/threonine phosphatase activity
OXB_RS10160	COG0515	serine threonine protein kinase
OXB_RS10160	COG2815	serine threonine protein kinase
OXB_RS10165	COG1162	GTPase activity
OXB_RS10170	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OXB_RS10180	COG0227	Belongs to the bacterial ribosomal protein bL28 family
OXB_RS10185	COG1302	Protein conserved in bacteria
OXB_RS10190	COG1461	Dihydroxyacetone kinase
OXB_RS10195	COG1760	l-serine dehydratase
OXB_RS10200	COG1760	l-serine dehydratase
OXB_RS10205	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OXB_RS10210	COG1349	DNA-binding transcription factor activity
OXB_RS10210	COG2050	protein possibly involved in aromatic compounds catabolism
OXB_RS10215	COG0416	fatty acid biosynthetic process
OXB_RS10220	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OXB_RS10225	COG1028	Short-chain dehydrogenase reductase Sdr
OXB_RS10230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OXB_RS10235	COG0571	ribonuclease III activity
OXB_RS10240	COG1196	nuclear chromosome segregation
OXB_RS10245	COG0552	protein localization to endoplasmic reticulum
OXB_RS10250	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
OXB_RS10255	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OXB_RS10260	COG0228	four-way junction DNA binding
OXB_RS10265	COG1837	Belongs to the UPF0109 family
OXB_RS10270	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OXB_RS10280	COG0335	large ribosomal subunit rRNA binding
OXB_RS10290	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OXB_RS10295	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OXB_RS10305	COG2257	FlhB HrpN YscU SpaS Family
OXB_RS10310	COG0045	succinate-CoA ligase (ADP-forming) activity
OXB_RS10315	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OXB_RS10320	COG0758	DNA mediated transformation
OXB_RS10325	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OXB_RS10335	COG4974	Belongs to the 'phage' integrase family
OXB_RS10345	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OXB_RS10350	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
OXB_RS10360	COG1815	bacterial-type flagellum-dependent cell motility
OXB_RS10365	COG1558	bacterial-type flagellum-dependent cell motility
OXB_RS10370	COG1677	Flagellar hook-basal body complex protein FliE
OXB_RS10375	COG1766	The M ring may be actively involved in energy transduction
OXB_RS10380	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OXB_RS10390	COG1157	protein secretion by the type III secretion system
OXB_RS10395	COG2882	bacterial-type flagellum organization
OXB_RS10410	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
OXB_RS10420	COG4786	Flagellar basal body rod
OXB_RS10425	COG1582	Flagellar protein (FlbD)
OXB_RS10430	COG1580	Controls the rotational direction of flagella during chemotaxis
OXB_RS10435	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OXB_RS10440	COG1776	CheC inhibitor of MCP methylation
OXB_RS10440	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OXB_RS10445	COG2201	protein-glutamate methylesterase activity
OXB_RS10450	COG3190	flagellar
OXB_RS10455	COG1338	Plays a role in the flagellum-specific transport system
OXB_RS10460	COG1987	bacterial-type flagellum assembly
OXB_RS10465	COG1684	flagellar biosynthetic protein fliR
OXB_RS10470	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OXB_RS10480	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OXB_RS10485	COG1419	protein localization to endoplasmic reticulum
OXB_RS10490	COG0455	bacterial-type flagellum organization
OXB_RS10495	COG2201	protein-glutamate methylesterase activity
OXB_RS10500	COG2198	Histidine kinase
OXB_RS10500	COG0643	Histidine kinase
OXB_RS10505	COG0835	chemotaxis
OXB_RS10510	COG1776	CheC inhibitor of MCP methylation
OXB_RS10515	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
OXB_RS10520	COG1191	sigma factor activity
OXB_RS10545	COG0528	UMP kinase activity
OXB_RS10550	COG0233	cytoplasmic translational termination
OXB_RS10555	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OXB_RS10560	COG4589	Belongs to the CDS family
OXB_RS10570	COG0750	zinc metalloprotease
OXB_RS10580	COG2176	DNA-directed DNA polymerase activity
OXB_RS10590	COG0195	Participates in both transcription termination and antitermination
OXB_RS10595	COG2740	Nucleic-acid-binding protein implicated in transcription termination
OXB_RS10600	COG1358	cellular component organization or biogenesis
OXB_RS10615	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OXB_RS10625	COG0196	riboflavin kinase activity
OXB_RS10630	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OXB_RS10635	COG0561	phosphatase activity
OXB_RS10645	COG0612	Peptidase, M16
OXB_RS10660	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OXB_RS10665	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OXB_RS10675	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OXB_RS10680	COG1674	ftsk spoiiie
OXB_RS10685	COG2188	Transcriptional regulator
OXB_RS10690	COG1744	ABC transporter substrate-binding protein PnrA-like
OXB_RS10695	COG3845	ABC transporter
OXB_RS10700	COG4603	Belongs to the binding-protein-dependent transport system permease family
OXB_RS10705	COG1079	Belongs to the binding-protein-dependent transport system permease family
OXB_RS10710	COG0612	Peptidase, M16
OXB_RS10715	COG0612	Peptidase, M16
OXB_RS10720	COG0300	oxidoreductase activity
OXB_RS10730	COG1426	Protein conserved in bacteria
OXB_RS10735	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OXB_RS10755	COG1692	metallophosphoesterase
OXB_RS10760	COG2359	stage V sporulation protein S
OXB_RS10765	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OXB_RS10770	COG4550	Control of competence regulator ComK, YlbF/YmcA
OXB_RS10785	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OXB_RS10790	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OXB_RS10810	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
OXB_RS10825	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OXB_RS10880	COG1073	alpha beta
OXB_RS10885	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OXB_RS10910	COG0596	Alpha beta hydrolase
OXB_RS10925	COG0697	spore germination
OXB_RS10930	COG1414	Transcriptional regulator
OXB_RS10935	COG1984	allophanate hydrolase subunit 2
OXB_RS10940	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
OXB_RS10945	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
OXB_RS10950	COG1914	H( )-stimulated, divalent metal cation uptake system
OXB_RS10960	COG4336	lyase activity
OXB_RS10970	COG0840	transmembrane signaling receptor activity
OXB_RS10975	COG2155	Conserved Protein
OXB_RS10980	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OXB_RS11000	COG0387	Pfam Sodium calcium exchanger
OXB_RS11030	COG2323	membrane
OXB_RS11035	COG0860	N-Acetylmuramoyl-L-alanine amidase
OXB_RS11040	COG0840	transmembrane signaling receptor activity
OXB_RS11065	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
OXB_RS11070	COG1653	transport
OXB_RS11080	COG0395	ABC-type sugar transport system, permease component
OXB_RS11090	COG3842	ATPase activity
OXB_RS11095	COG0647	UMP catabolic process
OXB_RS11100	COG0840	transmembrane signaling receptor activity
OXB_RS11115	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OXB_RS11125	COG1011	Hydrolase
OXB_RS11160	COG3773	Cell wall hydrolase
OXB_RS11165	COG0786	glutamate:sodium symporter activity
OXB_RS11175	COG0583	DNA-binding transcription factor activity
OXB_RS11180	COG2766	serine protein kinase
OXB_RS11185	COG2718	Belongs to the UPF0229 family
OXB_RS11190	COG2719	SpoVR family
OXB_RS11200	COG0488	(ABC) transporter
OXB_RS11205	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OXB_RS11210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OXB_RS11215	COG1116	anion transmembrane transporter activity
OXB_RS11220	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OXB_RS11225	COG0174	glutamine synthetase
OXB_RS11230	COG3377	Domain of unknown function (DUF1805)
OXB_RS11245	COG2076	Multidrug Resistance protein
OXB_RS11250	COG2076	Multidrug Resistance protein
OXB_RS11260	COG0584	glycerophosphoryl diester phosphodiesterase
OXB_RS11285	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
OXB_RS11290	COG0778	Nitroreductase
OXB_RS11300	COG2322	membrane
OXB_RS11310	COG2323	membrane
OXB_RS11325	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
OXB_RS11335	COG0688	phosphatidylethanolamine metabolic process
OXB_RS11345	COG2030	dehydratase
OXB_RS11365	COG1595	DNA-templated transcription, initiation
OXB_RS11375	COG1028	Short-chain dehydrogenase reductase Sdr
OXB_RS11380	COG3243	poly(R)-hydroxyalkanoic acid synthase
OXB_RS11385	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OXB_RS11390	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OXB_RS11410	COG0318	PFAM AMP-dependent synthetase and ligase
OXB_RS11420	COG2027	D-alanyl-D-alanine carboxypeptidase
OXB_RS11435	COG0564	pseudouridine synthase activity
OXB_RS11445	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OXB_RS11455	COG4120	Belongs to the binding-protein-dependent transport system permease family
OXB_RS11465	COG3300	MHYT domain
OXB_RS11465	COG5001	Diguanylate cyclase
OXB_RS11470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OXB_RS11475	COG0708	Exodeoxyribonuclease III
OXB_RS11480	COG2807	transmembrane transport
OXB_RS11485	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OXB_RS11490	COG2233	PERMEase
OXB_RS11495	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
OXB_RS11500	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OXB_RS11515	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OXB_RS11525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OXB_RS11535	COG0667	Aldo Keto reductase
OXB_RS11540	COG0494	nUDIX hydrolase
OXB_RS11550	COG0735	belongs to the Fur family
OXB_RS11555	COG4974	Belongs to the 'phage' integrase family
OXB_RS11565	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
OXB_RS11575	COG0305	Participates in initiation and elongation during chromosome replication
OXB_RS11595	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
OXB_RS11605	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
OXB_RS11620	COG1191	sigma factor activity
OXB_RS11625	COG0697	spore germination
OXB_RS11630	COG0019	diaminopimelate decarboxylase activity
OXB_RS11640	COG1547	Domain of unknown function (DUF309)
OXB_RS11655	COG1686	Belongs to the peptidase S11 family
OXB_RS11660	COG1187	pseudouridine synthase activity
OXB_RS11665	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OXB_RS11670	COG1333	cytochrome c biogenesis protein
OXB_RS11675	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OXB_RS11680	COG0745	RESPONSE REGULATOR receiver
OXB_RS11685	COG5002	protein histidine kinase activity
OXB_RS11690	COG1595	DNA-templated transcription, initiation
OXB_RS11700	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
OXB_RS11705	COG1141	Ferredoxin
OXB_RS11710	COG4955	Helix-turn-helix domain
OXB_RS11715	COG0514	ATP-dependent DNA helicase (RecQ)
OXB_RS11725	COG1408	metallophosphoesterase
OXB_RS11730	COG0492	ferredoxin-NADP+ reductase activity
OXB_RS11735	COG2339	peptidase activity
OXB_RS11740	COG3773	Cell wall hydrolase
OXB_RS11740	COG3409	Peptidoglycan-binding domain 1 protein
OXB_RS11765	COG0539	negative regulation of cytoplasmic translation
OXB_RS11790	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
OXB_RS11825	COG0105	UTP biosynthetic process
OXB_RS11830	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
OXB_RS11845	COG4401	Chorismate mutase type I
OXB_RS11855	COG0287	Prephenate dehydrogenase
OXB_RS11860	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OXB_RS11865	COG0457	Tetratricopeptide repeat
OXB_RS11880	COG0723	plastoquinol--plastocyanin reductase activity
OXB_RS11895	COG4347	Protein of unknown function (DUF1405)
OXB_RS11900	COG2738	Putative neutral zinc metallopeptidase
OXB_RS11905	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OXB_RS11910	COG1694	Mazg nucleotide pyrophosphohydrolase
OXB_RS11920	COG0438	transferase activity, transferring glycosyl groups
OXB_RS11930	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
OXB_RS11930	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
OXB_RS11945	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
OXB_RS11950	COG1199	ATP-dependent helicase activity
OXB_RS11950	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OXB_RS11965	COG3935	DnaD domain protein
OXB_RS11970	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OXB_RS11980	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OXB_RS11980	COG4499	WXG100 protein secretion system (Wss), protein YukC
OXB_RS11990	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OXB_RS12010	COG0786	glutamate:sodium symporter activity
OXB_RS12015	COG1301	dicarboxylic acid transport
OXB_RS12020	COG0805	protein transport
OXB_RS12025	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OXB_RS12040	COG0765	amino acid transport
OXB_RS12065	COG1012	belongs to the aldehyde dehydrogenase family
OXB_RS12070	COG2204	response regulator
OXB_RS12075	COG3852	Histidine kinase
OXB_RS12090	COG0494	nUDIX hydrolase
OXB_RS12100	COG4638	Rieske (2fe-2S)
OXB_RS12105	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
OXB_RS12110	COG1917	Cupin 2, conserved barrel domain protein
OXB_RS12110	COG4977	sequence-specific DNA binding
OXB_RS12115	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OXB_RS12150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OXB_RS12170	COG3336	cytochrome c oxidase
OXB_RS12175	COG0778	Nitroreductase
OXB_RS12185	COG1132	(ABC) transporter
OXB_RS12205	COG0753	catalase activity
OXB_RS12205	COG0693	protein deglycase activity
OXB_RS12245	COG5001	Diguanylate cyclase
OXB_RS12245	COG3300	MHYT domain
OXB_RS12250	COG3300	MHYT domain
OXB_RS12250	COG5001	Diguanylate cyclase
OXB_RS12255	COG0535	radical SAM domain protein
OXB_RS12270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OXB_RS12295	COG4842	Belongs to the WXG100 family
OXB_RS12300	COG5417	Belongs to the EsaB family
OXB_RS12305	COG4499	WXG100 protein secretion system (Wss), protein YukC
OXB_RS12310	COG0433	COG0433 Predicted ATPase
OXB_RS12310	COG1674	ftsk spoiiie
OXB_RS12315	COG1511	domain protein
OXB_RS12355	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OXB_RS12380	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OXB_RS12400	COG0765	amino acid transport
OXB_RS12405	COG1126	abc transporter atp-binding protein
OXB_RS12430	COG1834	amidinotransferase
OXB_RS12470	COG1205	dead DEAH box helicase
OXB_RS12470	COG1111	helicase
OXB_RS12495	COG3359	exonuclease
OXB_RS12500	COG3599	regulation of cell shape
OXB_RS12510	COG0116	Belongs to the methyltransferase superfamily
OXB_RS12515	COG1199	ATP-dependent helicase activity
OXB_RS12525	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
OXB_RS12540	COG0328	RNA-DNA hybrid ribonuclease activity
OXB_RS12555	COG1827	regulation of RNA biosynthetic process
OXB_RS12560	COG1104	cysteine desulfurase activity
OXB_RS12565	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
OXB_RS12570	COG0157	Belongs to the NadC ModD family
OXB_RS12575	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OXB_RS12580	COG2321	neutral zinc metallopeptidase
OXB_RS12600	COG4569	acetaldehyde dehydrogenase (acetylating) activity
OXB_RS12605	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OXB_RS12610	COG3971	2-oxopent-4-enoate hydratase activity
OXB_RS12620	COG1942	4-Oxalocrotonate Tautomerase
OXB_RS12635	COG0840	transmembrane signaling receptor activity
OXB_RS12650	COG0318	PFAM AMP-dependent synthetase and ligase
OXB_RS12660	COG1131	(ABC) transporter
OXB_RS12675	COG0488	(ABC) transporter
OXB_RS12690	COG2521	methyltransferase
OXB_RS12690	COG2136	Putative SAM-dependent methyltransferase
OXB_RS12700	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OXB_RS12705	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OXB_RS12710	COG1307	EDD domain protein, DegV family
OXB_RS12715	COG2755	lipolytic protein G-D-S-L family
OXB_RS12725	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OXB_RS12735	COG4479	Belongs to the UPF0346 family
OXB_RS12740	COG0813	purine-nucleoside phosphorylase activity
OXB_RS12745	COG0793	Belongs to the peptidase S41A family
OXB_RS12745	COG3409	Peptidoglycan-binding domain 1 protein
OXB_RS12755	COG2340	Cysteine-rich secretory protein family
OXB_RS12760	COG0697	spore germination
OXB_RS12775	COG0534	Mate efflux family protein
OXB_RS12780	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OXB_RS12785	COG0567	Dehydrogenase, E1 component
OXB_RS12790	COG0508	dehydrogenase complex catalyzes the overall conversion of
OXB_RS12800	COG0714	Associated with various cellular activities
OXB_RS12805	COG4548	von Willebrand factor, type A
OXB_RS12810	COG3853	Toxic anion resistance protein (TelA)
OXB_RS12815	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
OXB_RS12825	COG1278	Cold shock
OXB_RS12835	COG0488	(ABC) transporter
OXB_RS12845	COG1376	ErfK ybiS ycfS ynhG family protein
OXB_RS12860	COG1121	(ABC) transporter
OXB_RS12900	COG0840	transmembrane signaling receptor activity
OXB_RS12905	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OXB_RS12915	COG0628	permease
OXB_RS12935	COG1846	Transcriptional regulator
OXB_RS12940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OXB_RS12950	COG0697	spore germination
OXB_RS12970	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OXB_RS12975	COG3383	formate dehydrogenase (NAD+) activity
OXB_RS12980	COG2427	Protein of unknown function (DUF1641)
OXB_RS13000	COG5522	Integral membrane protein (intg_mem_TP0381)
OXB_RS13005	COG1388	LysM domain
OXB_RS13005	COG3858	chitin binding
OXB_RS13015	COG4260	virion core protein, lumpy skin disease virus
OXB_RS13025	COG0723	plastoquinol--plastocyanin reductase activity
OXB_RS13025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OXB_RS13045	COG5002	protein histidine kinase activity
OXB_RS13050	COG0745	RESPONSE REGULATOR receiver
OXB_RS13055	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OXB_RS13060	COG0187	DNA topoisomerase II activity
OXB_RS13065	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
OXB_RS13070	COG4841	protein insertion into membrane
OXB_RS13075	COG0318	PFAM AMP-dependent synthetase and ligase
OXB_RS13080	COG1028	Short-chain dehydrogenase reductase Sdr
OXB_RS13110	COG0411	ABC transporter
OXB_RS13120	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OXB_RS13125	COG2030	dehydratase
OXB_RS13130	COG0318	PFAM AMP-dependent synthetase and ligase
OXB_RS13145	COG2909	trisaccharide binding
OXB_RS13155	COG0824	Thioesterase
OXB_RS13160	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OXB_RS13165	COG1335	isochorismatase
OXB_RS13190	COG1999	signal sequence binding
OXB_RS13210	COG4846	Membrane protein involved in cytochrome C biogenesis
OXB_RS13215	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OXB_RS13220	COG0785	Cytochrome C biogenesis protein
OXB_RS13230	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OXB_RS13240	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OXB_RS13245	COG0477	Major facilitator Superfamily
OXB_RS13255	COG3300	MHYT domain
OXB_RS13255	COG5001	Diguanylate cyclase
OXB_RS13270	COG1061	Type III restriction enzyme res subunit
OXB_RS13275	COG0494	nUDIX hydrolase
OXB_RS13280	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OXB_RS13310	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OXB_RS13315	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OXB_RS13325	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
OXB_RS13340	COG0305	Participates in initiation and elongation during chromosome replication
OXB_RS13370	COG1595	DNA-templated transcription, initiation
OXB_RS13375	COG0726	polysaccharide deacetylase
OXB_RS13380	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
OXB_RS13380	COG2755	lipolytic protein G-D-S-L family
OXB_RS13390	COG3973	AAA domain
OXB_RS13400	COG0577	efflux transmembrane transporter activity
OXB_RS13405	COG1136	(ABC) transporter
OXB_RS13410	COG1819	glycosyl
OXB_RS13415	COG3620	sequence-specific DNA binding
OXB_RS13430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OXB_RS13435	COG2258	MOSC domain
OXB_RS13450	COG0183	Belongs to the thiolase family
OXB_RS13455	COG0318	PFAM AMP-dependent synthetase and ligase
OXB_RS13460	COG1268	BioY protein
OXB_RS13470	COG3485	protocatechuate 3,4-dioxygenase
OXB_RS13485	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OXB_RS13490	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OXB_RS13510	COG1414	Transcriptional regulator
OXB_RS13520	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OXB_RS13530	COG5002	protein histidine kinase activity
OXB_RS13545	COG0745	RESPONSE REGULATOR receiver
OXB_RS13595	COG2207	Transcriptional regulator
OXB_RS13605	COG0659	secondary active sulfate transmembrane transporter activity
OXB_RS13615	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OXB_RS13620	COG0300	oxidoreductase activity
OXB_RS13625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OXB_RS13630	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OXB_RS13635	COG1902	pentaerythritol trinitrate reductase activity
OXB_RS13645	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OXB_RS13650	COG0835	chemotaxis
OXB_RS13655	COG2195	Cleaves the N-terminal amino acid of tripeptides
OXB_RS13660	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OXB_RS13665	COG0346	lactoylglutathione lyase activity
OXB_RS13675	COG1703	isobutyryl-CoA mutase activity
OXB_RS13680	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OXB_RS13680	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OXB_RS13685	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OXB_RS13690	COG0508	dehydrogenase complex catalyzes the overall conversion of
OXB_RS13695	COG0022	dehydrogenase e1 component
OXB_RS13700	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OXB_RS13705	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OXB_RS13715	COG3829	transcription factor binding
OXB_RS13715	COG3290	protein histidine kinase activity
OXB_RS13725	COG0584	glycerophosphoryl diester phosphodiesterase
OXB_RS13740	COG0750	zinc metalloprotease
OXB_RS13745	COG0497	DNA recombination
OXB_RS13755	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
OXB_RS13760	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OXB_RS13765	COG0142	geranyltranstransferase activity
OXB_RS13790	COG1302	Protein conserved in bacteria
OXB_RS13795	COG0439	Biotin carboxylase
OXB_RS13800	COG0511	ligase activity, forming carbon-carbon bonds
OXB_RS13835	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OXB_RS13840	COG0006	proline dipeptidase activity
OXB_RS13850	COG3872	metal-dependent enzyme
OXB_RS13860	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OXB_RS13875	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OXB_RS13895	COG2030	dehydratase
OXB_RS13900	COG4670	ketone body catabolic process
OXB_RS13905	COG0583	DNA-binding transcription factor activity
OXB_RS13915	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
OXB_RS13920	COG0667	Aldo Keto reductase
OXB_RS13925	COG1609	Transcriptional regulator
OXB_RS13945	COG1012	belongs to the aldehyde dehydrogenase family
OXB_RS13965	COG0673	inositol 2-dehydrogenase activity
OXB_RS13975	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OXB_RS13980	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
OXB_RS13980	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
OXB_RS13985	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
OXB_RS13990	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OXB_RS14005	COG1012	belongs to the aldehyde dehydrogenase family
OXB_RS14010	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OXB_RS14015	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OXB_RS14020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OXB_RS14025	COG2186	Transcriptional regulator
OXB_RS14030	COG0710	3-dehydroquinate dehydratase activity
OXB_RS14045	COG0404	The glycine cleavage system catalyzes the degradation of glycine
OXB_RS14050	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OXB_RS14070	COG4537	Required for transformation and DNA binding
OXB_RS14080	COG1525	nuclease
OXB_RS14155	COG3628	GPW Gp25 family protein
OXB_RS14275	COG1783	phage Terminase large subunit
OXB_RS14280	COG5484	DNA packaging
OXB_RS14280	COG3728	DNA packaging
OXB_RS14315	COG3331	DNA recombination
OXB_RS14365	COG1484	DNA-dependent DNA replication
OXB_RS14460	COG0582	viral genome integration into host DNA
OXB_RS14470	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OXB_RS14480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OXB_RS14495	COG1368	sulfuric ester hydrolase activity
OXB_RS14505	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OXB_RS14510	COG0267	Belongs to the bacterial ribosomal protein bL33 family
OXB_RS14525	COG0768	penicillin binding
OXB_RS14535	COG2839	Protein conserved in bacteria
OXB_RS14555	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OXB_RS14560	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
OXB_RS14565	COG0735	belongs to the Fur family
OXB_RS14570	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OXB_RS14575	COG1121	(ABC) transporter
OXB_RS14590	COG0513	Belongs to the DEAD box helicase family
OXB_RS14620	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OXB_RS14625	COG0733	neurotransmitter:sodium symporter activity
OXB_RS14630	COG1522	sequence-specific DNA binding
OXB_RS14640	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OXB_RS14645	COG2384	SAM-dependent methyltransferase
OXB_RS14655	COG1960	acyl-CoA dehydrogenase activity
OXB_RS14665	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OXB_RS14670	COG0358	DNA primase activity
OXB_RS14680	COG0517	IMP dehydrogenase activity
OXB_RS14690	COG1381	Involved in DNA repair and RecF pathway recombination
OXB_RS14705	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
OXB_RS14715	COG1480	7TM receptor with intracellular HD hydrolase
OXB_RS14720	COG1702	phosphate starvation-inducible protein PhoH
OXB_RS14740	COG4864	UPF0365 protein
OXB_RS14745	COG1030	water channel activity
OXB_RS14770	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OXB_RS14790	COG4974	Belongs to the 'phage' integrase family
OXB_RS14920	COG0740	serine-type endopeptidase activity
OXB_RS14945	COG0582	viral genome integration into host DNA
OXB_RS15010	COG0305	Participates in initiation and elongation during chromosome replication
OXB_RS15055	COG1396	sequence-specific DNA binding
OXB_RS15080	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OXB_RS15085	COG2264	protein methyltransferase activity
OXB_RS15100	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OXB_RS15110	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OXB_RS15115	COG0481	GTPase activity
OXB_RS15125	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
OXB_RS15130	COG0268	Binds directly to 16S ribosomal RNA
OXB_RS15135	COG1466	dna polymerase III delta subunit
OXB_RS15145	COG2333	competence protein COMEC
OXB_RS15145	COG0658	competence protein
OXB_RS15150	COG2131	deaminase
OXB_RS15160	COG2226	methyltransferase
OXB_RS15165	COG0799	negative regulation of ribosome biogenesis
OXB_RS15170	COG1713	HD superfamily hydrolase involved in NAD metabolism
OXB_RS15175	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OXB_RS15180	COG1534	Rna-binding protein
OXB_RS15190	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OXB_RS15195	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
OXB_RS15215	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OXB_RS15220	COG0572	uridine kinase
OXB_RS15225	COG4122	O-methyltransferase activity
OXB_RS15230	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OXB_RS15235	COG3906	Belongs to the UPF0473 family
OXB_RS15240	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OXB_RS15245	COG4472	Bacterial protein of unknown function (DUF965)
OXB_RS15250	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OXB_RS15255	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OXB_RS15260	COG0457	Tetratricopeptide repeat
OXB_RS15270	COG1104	cysteine desulfurase activity
OXB_RS15275	COG1959	2 iron, 2 sulfur cluster binding
OXB_RS15280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OXB_RS15285	COG0835	chemotaxis
OXB_RS15285	COG0784	Response regulator, receiver
OXB_RS15295	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OXB_RS15300	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OXB_RS15310	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OXB_RS15315	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OXB_RS15330	COG3103	Sh3 type 3 domain protein
OXB_RS15330	COG4991	sh3 domain protein
OXB_RS15330	COG0860	N-Acetylmuramoyl-L-alanine amidase
OXB_RS15340	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OXB_RS15345	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OXB_RS15350	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
OXB_RS15350	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OXB_RS15355	COG5416	Lipopolysaccharide assembly protein A domain
OXB_RS15360	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OXB_RS15360	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OXB_RS15370	COG2244	polysaccharide biosynthetic process
OXB_RS15375	COG2323	membrane
OXB_RS15380	COG1862	Preprotein translocase
OXB_RS15385	COG0343	queuine tRNA-ribosyltransferase activity
OXB_RS15405	COG0217	transcriptional regulatory protein
OXB_RS15420	COG0077	Prephenate dehydratase
OXB_RS15430	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OXB_RS15450	COG2868	ribosomal protein
OXB_RS15475	COG2894	cell division
OXB_RS15480	COG0850	regulation of cytokinetic process
OXB_RS15490	COG1792	Involved in formation and maintenance of cell shape
OXB_RS15495	COG1077	Cell shape determining protein MreB Mrl
OXB_RS15500	COG2003	Belongs to the UPF0758 family
OXB_RS15505	COG0424	maF-like protein
OXB_RS15515	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
OXB_RS15540	COG1459	type II secretion system
OXB_RS15550	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OXB_RS15590	COG0285	dihydrofolate synthase activity
OXB_RS15595	COG0189	ligase activity
OXB_RS15610	COG0154	amidase activity
OXB_RS15615	COG0525	valine-tRNA ligase activity
OXB_RS15630	COG0113	porphobilinogen synthase activity
OXB_RS15645	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OXB_RS15655	COG0218	Necessary for normal cell division and for the maintenance of normal septation
OXB_RS15660	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
OXB_RS15670	COG0544	peptidyl-prolyl cis-trans isomerase activity
OXB_RS15685	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OXB_RS15685	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OXB_RS15695	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OXB_RS15700	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OXB_RS15705	COG1024	Enoyl-CoA hydratase
OXB_RS15710	COG1053	succinate dehydrogenase
OXB_RS15715	COG4670	ketone body catabolic process
OXB_RS15720	COG1960	acyl-CoA dehydrogenase activity
OXB_RS15725	COG1012	belongs to the aldehyde dehydrogenase family
OXB_RS15740	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OXB_RS15745	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
OXB_RS15745	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
OXB_RS15750	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
OXB_RS15750	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
OXB_RS15755	COG1929	Belongs to the glycerate kinase type-1 family
OXB_RS15760	COG1802	Transcriptional regulator
OXB_RS15775	COG1028	Short-chain dehydrogenase reductase Sdr
OXB_RS15785	COG2197	response regulator
OXB_RS15805	COG1012	belongs to the aldehyde dehydrogenase family
OXB_RS15830	COG0789	Transcriptional regulator
OXB_RS15830	COG4978	Transcriptional regulator
OXB_RS15840	COG2030	dehydratase
OXB_RS15860	COG3290	protein histidine kinase activity
OXB_RS15860	COG0840	transmembrane signaling receptor activity
OXB_RS15890	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OXB_RS15895	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OXB_RS15910	COG2197	response regulator
OXB_RS15915	COG0824	Thioesterase
OXB_RS15920	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OXB_RS15925	COG1053	succinate dehydrogenase
OXB_RS15930	COG2009	succinate dehydrogenase
OXB_RS15935	COG1719	4-vinyl reductase, 4VR
OXB_RS15940	COG0322	excinuclease ABC activity
OXB_RS15945	COG3118	belongs to the thioredoxin family
OXB_RS15950	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
OXB_RS15955	COG2086	electron transfer activity
OXB_RS15960	COG1024	Enoyl-CoA hydratase
OXB_RS15965	COG1309	transcriptional regulator
OXB_RS15970	COG0318	PFAM AMP-dependent synthetase and ligase
OXB_RS15975	COG3766	membrane
OXB_RS15980	COG1193	negative regulation of DNA recombination
OXB_RS15985	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
OXB_RS15985	COG1796	DNA polymerase
OXB_RS16015	COG0072	phenylalanine-tRNA ligase activity
OXB_RS16015	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OXB_RS16025	COG1335	isochorismatase
OXB_RS16040	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OXB_RS16050	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OXB_RS16055	COG1363	Peptidase, m42
OXB_RS16075	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OXB_RS16080	COG0514	ATP-dependent DNA helicase (RecQ)
OXB_RS16100	COG2188	Transcriptional regulator
OXB_RS16105	COG0726	polysaccharide deacetylase
OXB_RS16110	COG1054	Belongs to the UPF0176 family
OXB_RS16115	COG0492	ferredoxin-NADP+ reductase activity
OXB_RS16140	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OXB_RS16155	COG0604	alcohol dehydrogenase
OXB_RS16190	COG0291	Belongs to the bacterial ribosomal protein bL35 family
OXB_RS16195	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OXB_RS16200	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OXB_RS16205	COG1484	DNA-dependent DNA replication
OXB_RS16210	COG3611	Membrane attachment protein
OXB_RS16220	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OXB_RS16225	COG0237	dephospho-CoA kinase activity
OXB_RS16230	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OXB_RS16235	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OXB_RS16235	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OXB_RS16240	COG0330	HflC and HflK could
OXB_RS16245	COG0330	HflC and HflK could
OXB_RS16250	COG5002	protein histidine kinase activity
OXB_RS16255	COG0745	RESPONSE REGULATOR receiver
OXB_RS16265	COG0039	L-malate dehydrogenase activity
OXB_RS16270	COG0538	isocitrate dehydrogenase activity
OXB_RS16275	COG0372	Belongs to the citrate synthase family
OXB_RS16280	COG0628	permease
OXB_RS16285	COG3030	protein affecting phage T7 exclusion by the F plasmid
OXB_RS16295	COG0205	6-phosphofructokinase activity
OXB_RS16300	COG0825	malonyl-CoA metabolic process
OXB_RS16310	COG1725	Transcriptional regulator
OXB_RS16315	COG0587	DNA-directed DNA polymerase activity
OXB_RS16320	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
OXB_RS16330	COG4109	DRTGG domain
OXB_RS16340	COG0006	proline dipeptidase activity
OXB_RS16355	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OXB_RS16360	COG0827	DNA restriction-modification system
OXB_RS16365	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
OXB_RS16370	COG1714	RDD family
OXB_RS16375	COG0616	signal peptide processing
OXB_RS16380	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OXB_RS16390	COG2962	Rard protein
OXB_RS16395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OXB_RS16410	COG1104	cysteine desulfurase activity
OXB_RS16415	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
OXB_RS16420	COG1956	GAF domain-containing protein
OXB_RS16425	COG0626	cystathionine gamma-synthase activity
OXB_RS16430	COG2199	diguanylate cyclase activity
OXB_RS16430	COG2203	Gaf domain
OXB_RS16445	COG1793	dna ligase
OXB_RS16445	COG3285	dna ligase
OXB_RS16450	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
OXB_RS16455	COG0477	Major facilitator Superfamily
OXB_RS16460	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OXB_RS16465	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OXB_RS16475	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OXB_RS16480	COG0454	-acetyltransferase
OXB_RS16485	COG0517	IMP dehydrogenase activity
OXB_RS16490	COG0123	including yeast histone deacetylase and acetoin utilization protein
OXB_RS16500	COG1605	Chorismate mutase
OXB_RS16500	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
OXB_RS16505	COG0849	cell division
OXB_RS16525	COG1674	ftsk spoiiie
OXB_RS16530	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OXB_RS16535	COG4848	Belongs to the UPF0354 family
OXB_RS16545	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
OXB_RS16550	COG1363	Peptidase, m42
OXB_RS16565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OXB_RS16585	COG1349	DNA-binding transcription factor activity
OXB_RS16590	COG1187	pseudouridine synthase activity
OXB_RS16595	COG2244	polysaccharide biosynthetic process
OXB_RS16600	COG1012	belongs to the aldehyde dehydrogenase family
OXB_RS16610	COG2081	HI0933 family
OXB_RS16620	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OXB_RS16625	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OXB_RS16630	COG1242	4 iron, 4 sulfur cluster binding
OXB_RS16635	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
OXB_RS16640	COG1119	ATPase activity
OXB_RS16645	COG1028	Short-chain dehydrogenase reductase Sdr
OXB_RS16695	COG0628	permease
OXB_RS16700	COG0534	Mate efflux family protein
OXB_RS16705	COG3739	integral membrane protein
OXB_RS16710	COG3655	Transcriptional regulator
OXB_RS16735	COG3584	3D domain protein
OXB_RS16735	COG3583	domain protein
OXB_RS16740	COG1802	Transcriptional regulator
OXB_RS16745	COG1114	Component of the transport system for branched-chain amino acids
OXB_RS16755	COG0420	3'-5' exonuclease activity
OXB_RS16760	COG0803	Belongs to the bacterial solute-binding protein 9 family
OXB_RS16765	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OXB_RS16770	COG1121	(ABC) transporter
OXB_RS16790	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OXB_RS16795	COG2135	peptidase activity
OXB_RS16805	COG2814	Major facilitator Superfamily
OXB_RS16810	COG1846	Transcriptional regulator
OXB_RS16815	COG2223	nitrite transmembrane transporter activity
OXB_RS16820	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OXB_RS16850	COG1164	Oligoendopeptidase f
OXB_RS16855	COG1464	Belongs to the NlpA lipoprotein family
OXB_RS16860	COG1464	Belongs to the NlpA lipoprotein family
OXB_RS16865	COG2011	ABC-type metal ion transport system permease component
OXB_RS16870	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OXB_RS16875	COG0436	Aminotransferase
OXB_RS16890	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
OXB_RS16895	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OXB_RS16895	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OXB_RS16900	COG0307	riboflavin synthase, alpha
OXB_RS16905	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OXB_RS16905	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OXB_RS16915	COG2113	Glycine betaine
OXB_RS16920	COG4176	ABC-type proline glycine betaine transport system permease component
OXB_RS16925	COG4175	Glycine betaine
OXB_RS16925	COG0517	IMP dehydrogenase activity
OXB_RS16930	COG1510	regulation of RNA biosynthetic process
OXB_RS16935	COG0840	transmembrane signaling receptor activity
OXB_RS16935	COG3290	protein histidine kinase activity
OXB_RS16945	COG0745	RESPONSE REGULATOR receiver
OXB_RS16950	COG5002	protein histidine kinase activity
OXB_RS16955	COG1999	signal sequence binding
OXB_RS16970	COG0820	rRNA (adenine-C2-)-methyltransferase activity
OXB_RS16980	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OXB_RS16985	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OXB_RS16985	COG0140	phosphoribosyl-ATP diphosphatase activity
OXB_RS16990	COG0107	imidazoleglycerol-phosphate synthase activity
OXB_RS16995	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OXB_RS17000	COG0131	Imidazoleglycerol-phosphate dehydratase
OXB_RS17005	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OXB_RS17010	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OXB_RS17015	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
OXB_RS17020	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
OXB_RS17030	COG1595	DNA-templated transcription, initiation
OXB_RS17035	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OXB_RS17045	COG0697	spore germination
OXB_RS17070	COG1131	(ABC) transporter
OXB_RS17090	COG1012	belongs to the aldehyde dehydrogenase family
OXB_RS17095	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OXB_RS17100	COG1012	belongs to the aldehyde dehydrogenase family
OXB_RS17150	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
OXB_RS17160	COG4978	Transcriptional regulator
OXB_RS17160	COG0789	Transcriptional regulator
OXB_RS17170	COG0583	DNA-binding transcription factor activity
OXB_RS17190	COG0137	argininosuccinate synthase activity
OXB_RS17195	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OXB_RS17200	COG1388	LysM domain
OXB_RS17200	COG3858	chitin binding
OXB_RS17205	COG5577	PFAM Coat F domain
OXB_RS17215	COG0564	pseudouridine synthase activity
OXB_RS17230	COG0281	malic enzyme
OXB_RS17235	COG2323	membrane
OXB_RS17245	COG1960	acyl-CoA dehydrogenase activity
OXB_RS17255	COG2002	toxin-antitoxin pair type II binding
OXB_RS17265	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
OXB_RS17270	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OXB_RS17285	COG0739	heme binding
OXB_RS17290	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OXB_RS17295	COG1011	Hydrolase
OXB_RS17300	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
OXB_RS17310	COG0598	Magnesium transport protein CorA
OXB_RS17325	COG0840	transmembrane signaling receptor activity
OXB_RS17340	COG0490	domain, Protein
OXB_RS17340	COG0471	metal ion transport
OXB_RS17345	COG0753	catalase activity
OXB_RS17360	COG0745	RESPONSE REGULATOR receiver
OXB_RS17370	COG0840	transmembrane signaling receptor activity
OXB_RS17380	COG0697	spore germination
OXB_RS17390	COG2162	N-hydroxyarylamine O-acetyltransferase activity
OXB_RS17395	COG1012	belongs to the aldehyde dehydrogenase family
OXB_RS17400	COG1404	Belongs to the peptidase S8 family
OXB_RS17405	COG1132	(ABC) transporter
OXB_RS17410	COG0826	peptidase U32
OXB_RS17440	COG0745	RESPONSE REGULATOR receiver
OXB_RS17450	COG0133	tryptophan synthase activity
OXB_RS17455	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
OXB_RS17475	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
OXB_RS17490	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
OXB_RS17495	COG0726	polysaccharide deacetylase
OXB_RS17510	COG1982	Orn Lys Arg decarboxylase major
OXB_RS17515	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
OXB_RS17520	COG0010	Belongs to the arginase family
OXB_RS17540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OXB_RS17545	COG0765	amino acid transport
OXB_RS17550	COG1126	abc transporter atp-binding protein
OXB_RS17565	COG2124	cytochrome p450
OXB_RS17570	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OXB_RS17575	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
OXB_RS17580	COG1268	BioY protein
OXB_RS17585	COG1752	Esterase of the alpha-beta hydrolase superfamily
OXB_RS17590	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OXB_RS17595	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OXB_RS17600	COG3829	transcription factor binding
OXB_RS17605	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OXB_RS17610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OXB_RS17615	COG0765	amino acid transport
OXB_RS17620	COG1126	abc transporter atp-binding protein
OXB_RS17625	COG1648	precorrin-2 dehydrogenase activity
OXB_RS17625	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OXB_RS17640	COG0529	Catalyzes the synthesis of activated sulfate
OXB_RS17650	COG0175	sulfate reduction
OXB_RS17670	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
OXB_RS17675	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OXB_RS17680	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OXB_RS17695	COG0165	Argininosuccinate lyase
OXB_RS17715	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OXB_RS17725	COG1695	Transcriptional regulator
OXB_RS17745	COG1671	Belongs to the UPF0178 family
OXB_RS17755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OXB_RS17760	COG3424	synthase
OXB_RS17765	COG1755	Isoprenylcysteine carboxyl methyltransferase
OXB_RS17770	COG1757	Na H antiporter
OXB_RS17780	COG1525	nuclease
OXB_RS17785	COG1785	Belongs to the alkaline phosphatase family
OXB_RS17790	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OXB_RS17795	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OXB_RS17800	COG0210	DNA helicase
OXB_RS17810	COG0681	Belongs to the peptidase S26 family
OXB_RS17815	COG0840	transmembrane signaling receptor activity
OXB_RS17820	COG2267	carboxylic ester hydrolase activity
OXB_RS17825	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OXB_RS17865	COG2197	response regulator
OXB_RS17880	COG0805	protein transport
OXB_RS17905	COG2340	Cysteine-rich secretory protein family
OXB_RS17940	COG0860	N-Acetylmuramoyl-L-alanine amidase
OXB_RS17950	COG0840	transmembrane signaling receptor activity
OXB_RS17955	COG0741	lytic transglycosylase activity
OXB_RS17955	COG0739	heme binding
OXB_RS17955	COG1196	nuclear chromosome segregation
OXB_RS17960	COG5002	protein histidine kinase activity
OXB_RS17990	COG0732	type I restriction modification DNA specificity domain
OXB_RS17995	COG0142	geranyltranstransferase activity
OXB_RS18040	COG1361	Conserved repeat domain
OXB_RS18060	COG1522	sequence-specific DNA binding
OXB_RS18115	COG0517	IMP dehydrogenase activity
OXB_RS18115	COG1994	Peptidase M50
OXB_RS18145	COG4980	gas vesicle protein
OXB_RS18150	COG5002	protein histidine kinase activity
OXB_RS18155	COG5001	Diguanylate cyclase
OXB_RS18155	COG4251	negative regulation of phosphorylation
OXB_RS18155	COG2203	Gaf domain
OXB_RS18155	COG3706	GGDEF domain