locus-tag	class	description
H7F26_RS00005	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H7F26_RS00025	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H7F26_RS00035	COG0301	tRNA thio-modification
H7F26_RS00040	COG1104	cysteine desulfurase activity
H7F26_RS00045	COG1114	Component of the transport system for branched-chain amino acids
H7F26_RS00055	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
H7F26_RS00060	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
H7F26_RS00065	COG1309	transcriptional regulator
H7F26_RS00070	COG1956	GAF domain-containing protein
H7F26_RS00075	COG2203	Gaf domain
H7F26_RS00075	COG2199	diguanylate cyclase activity
H7F26_RS00080	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
H7F26_RS00090	COG3152	Membrane
H7F26_RS00095	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
H7F26_RS00100	COG1522	sequence-specific DNA binding
H7F26_RS00110	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H7F26_RS00115	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H7F26_RS00120	COG0454	-acetyltransferase
H7F26_RS00125	COG0517	IMP dehydrogenase activity
H7F26_RS00130	COG0123	including yeast histone deacetylase and acetoin utilization protein
H7F26_RS00135	COG1360	Flagellar Motor Protein
H7F26_RS00140	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
H7F26_RS00145	COG1609	Transcriptional regulator
H7F26_RS00150	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
H7F26_RS00150	COG1605	Chorismate mutase
H7F26_RS00160	COG3118	belongs to the thioredoxin family
H7F26_RS00165	COG4980	gas vesicle protein
H7F26_RS00170	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
H7F26_RS00175	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H7F26_RS00180	COG1674	ftsk spoiiie
H7F26_RS00185	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7F26_RS00190	COG4848	Belongs to the UPF0354 family
H7F26_RS00195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F26_RS00205	COG1363	Peptidase, m42
H7F26_RS00210	COG5584	Small secreted protein
H7F26_RS00215	COG0281	malic enzyme
H7F26_RS00220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7F26_RS00225	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H7F26_RS00235	COG0510	thiamine kinase activity
H7F26_RS00240	COG1523	belongs to the glycosyl hydrolase 13 family
H7F26_RS00245	COG1597	lipid kinase activity
H7F26_RS00255	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
H7F26_RS00260	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H7F26_RS00275	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H7F26_RS00280	COG2252	PERMEase
H7F26_RS00285	COG1349	DNA-binding transcription factor activity
H7F26_RS00290	COG1187	pseudouridine synthase activity
H7F26_RS00295	COG2244	polysaccharide biosynthetic process
H7F26_RS00300	COG2081	HI0933 family
H7F26_RS00305	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H7F26_RS00315	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H7F26_RS00320	COG0457	Tetratricopeptide repeat
H7F26_RS00330	COG5578	integral membrane protein
H7F26_RS00335	COG0673	inositol 2-dehydrogenase activity
H7F26_RS00340	COG1653	transport
H7F26_RS00345	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
H7F26_RS00350	COG4209	transmembrane transport
H7F26_RS00355	COG2207	Transcriptional regulator
H7F26_RS00360	COG1653	transport
H7F26_RS00365	COG0395	ABC-type sugar transport system, permease component
H7F26_RS00370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H7F26_RS00375	COG1073	alpha beta
H7F26_RS00385	COG0583	DNA-binding transcription factor activity
H7F26_RS00390	COG0346	lactoylglutathione lyase activity
H7F26_RS00395	COG0495	leucyl-tRNA aminoacylation
H7F26_RS00405	COG2814	Major facilitator Superfamily
H7F26_RS00415	COG2433	Pfam Transposase IS66
H7F26_RS00420	COG0577	efflux transmembrane transporter activity
H7F26_RS00425	COG1136	(ABC) transporter
H7F26_RS00435	COG1131	(ABC) transporter
H7F26_RS00440	COG1725	Transcriptional regulator
H7F26_RS00450	COG1242	4 iron, 4 sulfur cluster binding
H7F26_RS00455	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
H7F26_RS00460	COG1301	dicarboxylic acid transport
H7F26_RS00470	COG2267	carboxylic ester hydrolase activity
H7F26_RS00475	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H7F26_RS00485	COG0438	transferase activity, transferring glycosyl groups
H7F26_RS00485	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
H7F26_RS00490	COG0367	asparagine synthase
H7F26_RS00495	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
H7F26_RS00500	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
H7F26_RS00515	COG1506	peptidase
H7F26_RS00520	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7F26_RS00525	COG1116	anion transmembrane transporter activity
H7F26_RS00530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7F26_RS00535	COG0494	nUDIX hydrolase
H7F26_RS00545	COG4824	toxin secretion phage lysis holin
H7F26_RS00550	COG0783	Belongs to the Dps family
H7F26_RS00565	COG1854	S-ribosylhomocysteine lyase activity
H7F26_RS00570	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
H7F26_RS00575	COG0288	reversible hydration of carbon dioxide
H7F26_RS00580	COG0523	cobalamin synthesis protein
H7F26_RS00585	COG0803	Belongs to the bacterial solute-binding protein 9 family
H7F26_RS00590	COG0254	rRNA binding
H7F26_RS00595	COG1271	oxidase subunit
H7F26_RS00600	COG1294	oxidase, subunit
H7F26_RS00615	COG4948	Mandelate Racemase Muconate Lactonizing
H7F26_RS00620	COG0318	PFAM AMP-dependent synthetase and ligase
H7F26_RS00625	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
H7F26_RS00630	COG0596	Alpha beta hydrolase
H7F26_RS00635	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
H7F26_RS00640	COG1169	isochorismate synthase
H7F26_RS00645	COG1575	Belongs to the MenA family. Type 1 subfamily
H7F26_RS00650	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H7F26_RS00665	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
H7F26_RS00670	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
H7F26_RS00675	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
H7F26_RS00795	COG1609	Transcriptional regulator
H7F26_RS00800	COG3859	Proton-coupled thiamine transporter YuaJ
H7F26_RS00805	COG3764	Sortase (surface protein transpeptidase)
H7F26_RS00820	COG0457	Tetratricopeptide repeat
H7F26_RS00825	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
H7F26_RS00830	COG0569	domain protein
H7F26_RS00835	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H7F26_RS00845	COG2318	DinB family
H7F26_RS00855	COG1454	alcohol dehydrogenase
H7F26_RS00860	COG1012	belongs to the aldehyde dehydrogenase family
H7F26_RS00865	COG1510	regulation of RNA biosynthetic process
H7F26_RS00875	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
H7F26_RS00880	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H7F26_RS00885	COG2140	Oxalate decarboxylase
H7F26_RS00920	COG1397	ADP-ribosylglycohydrolase
H7F26_RS00955	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
H7F26_RS00970	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
H7F26_RS00975	COG0726	polysaccharide deacetylase
H7F26_RS00980	COG1408	metallophosphoesterase
H7F26_RS00985	COG1968	undecaprenyl-diphosphatase activity
H7F26_RS00990	COG0628	permease
H7F26_RS00995	COG0673	inositol 2-dehydrogenase activity
H7F26_RS01000	COG0693	protein deglycase activity
H7F26_RS01005	COG0840	transmembrane signaling receptor activity
H7F26_RS01010	COG0840	transmembrane signaling receptor activity
H7F26_RS01025	COG2070	2-Nitropropane dioxygenase
H7F26_RS01030	COG0432	Pfam Uncharacterised protein family UPF0047
H7F26_RS01050	COG5297	Belongs to the glycosyl hydrolase family 6
H7F26_RS01055	COG1253	flavin adenine dinucleotide binding
H7F26_RS01060	COG2738	Putative neutral zinc metallopeptidase
H7F26_RS01070	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H7F26_RS01080	COG2323	membrane
H7F26_RS01085	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
H7F26_RS01095	COG0166	Belongs to the GPI family
H7F26_RS01100	COG1979	alcohol dehydrogenase
H7F26_RS01105	COG2155	Conserved Protein
H7F26_RS01110	COG1098	S1 RNA binding domain
H7F26_RS01115	COG0436	Aminotransferase
H7F26_RS01120	COG1522	sequence-specific DNA binding
H7F26_RS01125	COG2267	carboxylic ester hydrolase activity
H7F26_RS01140	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
H7F26_RS01155	COG5018	Exonuclease
H7F26_RS01160	COG2814	Major facilitator Superfamily
H7F26_RS01165	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H7F26_RS01170	COG3011	Protein conserved in bacteria
H7F26_RS01180	COG3290	protein histidine kinase activity
H7F26_RS01185	COG4565	transcriptional regulatory protein
H7F26_RS01195	COG1183	phosphatidylcholine synthase activity
H7F26_RS01200	COG0586	Pfam SNARE associated Golgi protein
H7F26_RS01205	COG0688	phosphatidylethanolamine metabolic process
H7F26_RS01210	COG3493	citrate carrier protein
H7F26_RS01220	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H7F26_RS01220	COG2111	Na H antiporter
H7F26_RS01225	COG2111	Na H antiporter
H7F26_RS01230	COG1006	Multisubunit Na H antiporter MnhC subunit
H7F26_RS01235	COG0651	ATP synthesis coupled electron transport
H7F26_RS01240	COG1863	multisubunit Na H antiporter MnhE subunit
H7F26_RS01245	COG2212	antiporter activity
H7F26_RS01250	COG1320	monovalent cation:proton antiporter activity
H7F26_RS01255	COG2050	protein possibly involved in aromatic compounds catabolism
H7F26_RS01260	COG2197	response regulator
H7F26_RS01265	COG4585	Histidine kinase
H7F26_RS01290	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
H7F26_RS01295	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
H7F26_RS01300	COG1335	isochorismatase
H7F26_RS01305	COG5506	Protein of unknown function (DUF1694)
H7F26_RS01320	COG0628	permease
H7F26_RS01325	COG1959	2 iron, 2 sulfur cluster binding
H7F26_RS01330	COG0657	acetylesterase activity
H7F26_RS01340	COG1418	mRNA catabolic process
H7F26_RS01345	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_RS01355	COG1511	domain protein
H7F26_RS01360	COG0433	COG0433 Predicted ATPase
H7F26_RS01360	COG1674	ftsk spoiiie
H7F26_RS01365	COG4499	WXG100 protein secretion system (Wss), protein YukC
H7F26_RS01370	COG5417	Belongs to the EsaB family
H7F26_RS01375	COG4842	Belongs to the WXG100 family
H7F26_RS01380	COG1115	amino acid carrier protein
H7F26_RS01385	COG2508	Transcriptional regulator
H7F26_RS01385	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
H7F26_RS01390	COG0686	Belongs to the AlaDH PNT family
H7F26_RS01400	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
H7F26_RS01405	COG1268	BioY protein
H7F26_RS01410	COG2056	Na+-H+ antiporter family
H7F26_RS01415	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
H7F26_RS01420	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
H7F26_RS01425	COG3584	3D domain protein
H7F26_RS01440	COG1252	NADH dehydrogenase
H7F26_RS01445	COG0492	ferredoxin-NADP+ reductase activity
H7F26_RS01460	COG0456	acetyltransferase
H7F26_RS01465	COG0316	Belongs to the HesB IscA family
H7F26_RS01470	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
H7F26_RS01475	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H7F26_RS01480	COG4844	belongs to the
H7F26_RS01485	COG1252	NADH dehydrogenase
H7F26_RS01490	COG5646	InterPro IPR014922
H7F26_RS01500	COG0457	Tetratricopeptide repeat
H7F26_RS01505	COG3479	Phenolic acid decarboxylase
H7F26_RS01515	COG4837	Protein of unknown function (DUF1462)
H7F26_RS01520	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
H7F26_RS01525	COG1506	peptidase
H7F26_RS01525	COG0823	Involved in the tonB-independent uptake of proteins
H7F26_RS01525	COG4946	Tricorn protease homolog
H7F26_RS01530	COG0083	homoserine kinase activity
H7F26_RS01535	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H7F26_RS01540	COG0460	homoserine dehydrogenase
H7F26_RS01550	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H7F26_RS01555	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H7F26_RS01560	COG0647	UMP catabolic process
H7F26_RS01565	COG2445	Protein of unknown function DUF86
H7F26_RS01570	COG4470	Protein conserved in bacteria
H7F26_RS01585	COG0739	heme binding
H7F26_RS01595	COG0733	neurotransmitter:sodium symporter activity
H7F26_RS01605	COG3377	Domain of unknown function (DUF1805)
H7F26_RS01610	COG0737	Belongs to the 5'-nucleotidase family
H7F26_RS01615	COG0730	response to heat
H7F26_RS01620	COG1801	Protein of unknown function DUF72
H7F26_RS01630	COG3226	Transcriptional regulator
H7F26_RS01640	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H7F26_RS01645	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H7F26_RS01650	COG2508	Transcriptional regulator
H7F26_RS01655	COG2814	Major facilitator Superfamily
H7F26_RS01660	COG1288	antiporter activity
H7F26_RS01665	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H7F26_RS01670	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H7F26_RS01675	COG2356	endonuclease I
H7F26_RS01685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H7F26_RS01700	COG0457	Tetratricopeptide repeat
H7F26_RS01705	COG0719	Fe-S assembly protein
H7F26_RS01710	COG0822	iron-sulfur transferase activity
H7F26_RS01715	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H7F26_RS01720	COG0719	Fe-S assembly protein
H7F26_RS01725	COG0396	ATPase activity
H7F26_RS01735	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H7F26_RS01740	COG1464	Belongs to the NlpA lipoprotein family
H7F26_RS01745	COG2011	ABC-type metal ion transport system permease component
H7F26_RS01750	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H7F26_RS01760	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F26_RS01765	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
H7F26_RS01775	COG0509	glycine decarboxylation via glycine cleavage system
H7F26_RS01780	COG1393	Belongs to the ArsC family
H7F26_RS01785	COG1960	acyl-CoA dehydrogenase activity
H7F26_RS01790	COG0183	Belongs to the thiolase family
H7F26_RS01795	COG1250	3-hydroxyacyl-CoA dehydrogenase
H7F26_RS01795	COG1024	Enoyl-CoA hydratase
H7F26_RS01810	COG5577	PFAM Coat F domain
H7F26_RS01825	COG1120	ATPase activity
H7F26_RS01830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F26_RS01835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F26_RS01840	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H7F26_RS01855	COG1686	Belongs to the peptidase S11 family
H7F26_RS01860	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_RS01865	COG0783	Belongs to the Dps family
H7F26_RS01870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7F26_RS01875	COG0745	RESPONSE REGULATOR receiver
H7F26_RS01880	COG2205	protein histidine kinase activity
H7F26_RS01880	COG2770	Histidine kinase
H7F26_RS01890	COG1309	transcriptional regulator
H7F26_RS01895	COG0114	fumarate hydratase activity
H7F26_RS01905	COG0697	spore germination
H7F26_RS01910	COG0814	amino acid
H7F26_RS01925	COG2197	response regulator
H7F26_RS01930	COG4585	Histidine kinase
H7F26_RS01935	COG4758	membrane
H7F26_RS01945	COG1842	Phage shock protein A
H7F26_RS01950	COG4758	membrane
H7F26_RS01955	COG4677	pectinesterase activity
H7F26_RS01960	COG2096	Adenosyltransferase
H7F26_RS01965	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_RS01975	COG1454	alcohol dehydrogenase
H7F26_RS01980	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H7F26_RS01985	COG1120	ATPase activity
H7F26_RS01990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F26_RS01995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H7F26_RS02000	COG1802	Transcriptional regulator
H7F26_RS02005	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_RS02010	COG2258	MOSC domain
H7F26_RS02015	COG0583	DNA-binding transcription factor activity
H7F26_RS02025	COG2721	sulfolactate sulfo-lyase activity
H7F26_RS02030	COG0246	Mannitol dehydrogenase
H7F26_RS02035	COG1609	Transcriptional regulator
H7F26_RS02040	COG2211	Major facilitator Superfamily
H7F26_RS02045	COG1904	glucuronate isomerase
H7F26_RS02050	COG2205	protein histidine kinase activity
H7F26_RS02055	COG0745	RESPONSE REGULATOR receiver
H7F26_RS02060	COG1120	ATPase activity
H7F26_RS02065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F26_RS02070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F26_RS02075	COG0531	amino acid
H7F26_RS02085	COG1988	membrane-bound metal-dependent
H7F26_RS02090	COG1368	sulfuric ester hydrolase activity
H7F26_RS02095	COG2814	Major facilitator Superfamily
H7F26_RS02100	COG0656	L-ascorbic acid biosynthetic process
H7F26_RS02105	COG1940	carbohydrate kinase activity
H7F26_RS02110	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H7F26_RS02120	COG3973	AAA domain
H7F26_RS02125	COG2860	membrane
H7F26_RS02130	COG0456	acetyltransferase
H7F26_RS02130	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
H7F26_RS02135	COG0456	acetyltransferase
H7F26_RS02140	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
H7F26_RS02145	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H7F26_RS02150	COG2217	Heavy metal translocating P-type atpase
H7F26_RS02155	COG1653	transport
H7F26_RS02160	COG1175	transmembrane transport
H7F26_RS02165	COG0395	ABC-type sugar transport system, permease component
H7F26_RS02170	COG1501	Belongs to the glycosyl hydrolase 31 family
H7F26_RS02175	COG1472	Belongs to the glycosyl hydrolase 3 family
H7F26_RS02180	COG1121	(ABC) transporter
H7F26_RS02185	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H7F26_RS02190	COG0803	Belongs to the bacterial solute-binding protein 9 family
H7F26_RS02205	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
H7F26_RS02205	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
H7F26_RS02210	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7F26_RS02210	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7F26_RS02210	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F26_RS02230	COG2217	Heavy metal translocating P-type atpase
H7F26_RS02235	COG2608	mercury ion transmembrane transporter activity
H7F26_RS02240	COG1937	Protein conserved in bacteria
H7F26_RS02245	COG0693	protein deglycase activity
H7F26_RS02250	COG1349	DNA-binding transcription factor activity
H7F26_RS02255	COG1070	Carbohydrate kinase
H7F26_RS02260	COG4952	isomerase
H7F26_RS02270	COG3347	Dehydrogenase
H7F26_RS02270	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_RS02275	COG2814	Major facilitator Superfamily
H7F26_RS02280	COG2814	Major facilitator Superfamily
H7F26_RS02290	COG2124	cytochrome p450
H7F26_RS02300	COG1846	Transcriptional regulator
H7F26_RS02310	COG0673	inositol 2-dehydrogenase activity
H7F26_RS02315	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H7F26_RS02320	COG1054	Belongs to the UPF0176 family
H7F26_RS02330	COG1191	sigma factor activity
H7F26_RS02340	COG2140	Oxalate decarboxylase
H7F26_RS02390	COG5444	nuclease activity
H7F26_RS02445	COG1705	Flagellar rod assembly protein muramidase FlgJ
H7F26_RS02520	COG4626	Terminase
H7F26_RS02520	COG1802	Transcriptional regulator
H7F26_RS02545	COG0582	viral genome integration into host DNA
H7F26_RS02630	COG1396	sequence-specific DNA binding
H7F26_RS02640	COG0582	viral genome integration into host DNA
H7F26_RS02650	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
H7F26_RS02655	COG0557	exoribonuclease II activity
H7F26_RS02660	COG1647	Serine aminopeptidase, S33
H7F26_RS02665	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H7F26_RS02670	COG2002	toxin-antitoxin pair type II binding
H7F26_RS02675	COG1476	TRANSCRIPTIONal
H7F26_RS02680	COG1396	sequence-specific DNA binding
H7F26_RS02685	COG1396	sequence-specific DNA binding
H7F26_RS02690	COG1174	glycine betaine transport
H7F26_RS02695	COG1732	Glycine betaine
H7F26_RS02700	COG1174	glycine betaine transport
H7F26_RS02705	COG1125	glycine betaine transport
H7F26_RS02705	COG0517	IMP dehydrogenase activity
H7F26_RS02710	COG1510	regulation of RNA biosynthetic process
H7F26_RS02715	COG2095	MarC family integral membrane protein
H7F26_RS02725	COG4640	response to antibiotic
H7F26_RS02730	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H7F26_RS02740	COG0693	protein deglycase activity
H7F26_RS02745	COG0148	phosphopyruvate hydratase activity
H7F26_RS02750	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
H7F26_RS02755	COG0149	triose-phosphate isomerase activity
H7F26_RS02760	COG0126	phosphoglycerate kinase activity
H7F26_RS02765	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H7F26_RS02770	COG2390	Transcriptional regulator
H7F26_RS02775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7F26_RS02780	COG1113	amino acid transport
H7F26_RS02800	COG1556	Lactate utilization protein
H7F26_RS02805	COG1139	Iron-sulfur cluster binding protein
H7F26_RS02810	COG0247	lactate metabolic process
H7F26_RS02815	COG2186	Transcriptional regulator
H7F26_RS02820	COG1620	l-lactate permease
H7F26_RS02825	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
H7F26_RS02835	COG5039	Polysaccharide pyruvyl transferase
H7F26_RS02840	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H7F26_RS02845	COG0110	maltose O-acetyltransferase activity
H7F26_RS02850	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H7F26_RS02855	COG2244	polysaccharide biosynthetic process
H7F26_RS02860	COG1216	Glycosyl transferase, family 2
H7F26_RS02865	COG5039	Polysaccharide pyruvyl transferase
H7F26_RS02870	COG1216	Glycosyl transferase, family 2
H7F26_RS02880	COG0438	transferase activity, transferring glycosyl groups
H7F26_RS02885	COG1215	transferase activity, transferring glycosyl groups
H7F26_RS02890	COG0438	transferase activity, transferring glycosyl groups
H7F26_RS02895	COG1086	Polysaccharide biosynthesis protein
H7F26_RS02900	COG0489	protein tyrosine kinase activity
H7F26_RS02905	COG3944	biosynthesis protein
H7F26_RS02910	COG1396	sequence-specific DNA binding
H7F26_RS02915	COG2249	NAD(P)H dehydrogenase (quinone) activity
H7F26_RS02920	COG2271	Major facilitator Superfamily
H7F26_RS02930	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
H7F26_RS02945	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H7F26_RS02955	COG1733	regulation of RNA biosynthetic process
H7F26_RS02960	COG1902	pentaerythritol trinitrate reductase activity
H7F26_RS02965	COG1621	beta-fructofuranosidase activity
H7F26_RS02970	COG1621	beta-fructofuranosidase activity
H7F26_RS02985	COG0740	serine-type endopeptidase activity
H7F26_RS02990	COG1611	Belongs to the LOG family
H7F26_RS02995	COG1694	Mazg nucleotide pyrophosphohydrolase
H7F26_RS03000	COG1078	dGTPase activity
H7F26_RS03005	COG0659	secondary active sulfate transmembrane transporter activity
H7F26_RS03010	COG0288	reversible hydration of carbon dioxide
H7F26_RS03015	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H7F26_RS03020	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H7F26_RS03025	COG0640	Transcriptional regulator
H7F26_RS03035	COG2732	(Barnase) inhibitor
H7F26_RS03040	COG2162	N-hydroxyarylamine O-acetyltransferase activity
H7F26_RS03045	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F26_RS03050	COG1481	regulation of sporulation
H7F26_RS03055	COG0391	Required for morphogenesis under gluconeogenic growth conditions
H7F26_RS03060	COG1660	Displays ATPase and GTPase activities
H7F26_RS03065	COG1051	belongs to the nudix hydrolase family
H7F26_RS03070	COG0492	ferredoxin-NADP+ reductase activity
H7F26_RS03075	COG0457	Tetratricopeptide repeat
H7F26_RS03080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7F26_RS03085	COG0140	phosphoribosyl-ATP diphosphatase activity
H7F26_RS03085	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H7F26_RS03090	COG0107	imidazoleglycerol-phosphate synthase activity
H7F26_RS03095	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
H7F26_RS03100	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H7F26_RS03105	COG0131	Imidazoleglycerol-phosphate dehydratase
H7F26_RS03110	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H7F26_RS03115	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
H7F26_RS03120	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
H7F26_RS03125	COG4990	cell redox homeostasis
H7F26_RS03130	COG5297	Belongs to the glycosyl hydrolase family 6
H7F26_RS03135	COG0110	maltose O-acetyltransferase activity
H7F26_RS03140	COG0546	phosphoglycolate phosphatase activity
H7F26_RS03145	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
H7F26_RS03150	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
H7F26_RS03155	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
H7F26_RS03160	COG1846	Transcriptional regulator
H7F26_RS03165	COG2814	Major facilitator Superfamily
H7F26_RS03170	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H7F26_RS03175	COG1950	PFAM Membrane protein of
H7F26_RS03180	COG1983	PspC domain protein
H7F26_RS03185	COG3595	metallopeptidase activity
H7F26_RS03205	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H7F26_RS03210	COG0556	nucleotide-excision repair
H7F26_RS03215	COG4897	Protein conserved in bacteria
H7F26_RS03225	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7F26_RS03235	COG0793	Belongs to the peptidase S41A family
H7F26_RS03235	COG3409	Peptidoglycan-binding domain 1 protein
H7F26_RS03240	COG0473	3-isopropylmalate dehydrogenase activity
H7F26_RS03245	COG0791	NLP P60 protein
H7F26_RS03245	COG3883	PFAM NLP P60 protein
H7F26_RS03250	COG2177	Part of the ABC transporter FtsEX involved in
H7F26_RS03255	COG2884	Cell division ATP-binding protein ftsE
H7F26_RS03260	COG2010	Cytochrome c
H7F26_RS03265	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H7F26_RS03275	COG0653	protein targeting
H7F26_RS03280	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
H7F26_RS03295	COG1516	flagellar protein fliS
H7F26_RS03300	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
H7F26_RS03305	COG1334	flagellar protein FlaG
H7F26_RS03310	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H7F26_RS03315	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
H7F26_RS03320	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
H7F26_RS03330	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H7F26_RS03335	COG1256	bacterial-type flagellum assembly
H7F26_RS03335	COG4786	Flagellar basal body rod
H7F26_RS03340	COG3418	PFAM FlgN family protein
H7F26_RS03345	COG2747	anti-sigma28 factor FlgM
H7F26_RS03355	COG1040	competence protein
H7F26_RS03365	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
H7F26_RS03370	COG1307	EDD domain protein, DegV family
H7F26_RS03375	COG2197	response regulator
H7F26_RS03380	COG4585	Histidine kinase
H7F26_RS03385	COG1739	Uncharacterized protein family UPF0029
H7F26_RS03390	COG1316	TRANSCRIPTIONal
H7F26_RS03400	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H7F26_RS03405	COG0438	transferase activity, transferring glycosyl groups
H7F26_RS03410	COG1215	transferase activity, transferring glycosyl groups
H7F26_RS03415	COG3206	protein involved in exopolysaccharide biosynthesis
H7F26_RS03420	COG3307	-O-antigen
H7F26_RS03425	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H7F26_RS03430	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
H7F26_RS03435	COG0297	glycogen (starch) synthase activity
H7F26_RS03435	COG0438	transferase activity, transferring glycosyl groups
H7F26_RS03440	COG2244	polysaccharide biosynthetic process
H7F26_RS03450	COG0860	N-Acetylmuramoyl-L-alanine amidase
H7F26_RS03450	COG2247	cell wall binding repeat
H7F26_RS03455	COG2385	sporulation resulting in formation of a cellular spore
H7F26_RS03455	COG2247	cell wall binding repeat
H7F26_RS03465	COG1316	TRANSCRIPTIONal
H7F26_RS03470	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
H7F26_RS03475	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H7F26_RS03480	COG1134	teichoic acid transport
H7F26_RS03485	COG1682	transport, permease protein
H7F26_RS03500	COG0463	Glycosyl transferase, family 2
H7F26_RS03500	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
H7F26_RS03505	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
H7F26_RS03510	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
H7F26_RS03515	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
H7F26_RS03520	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
H7F26_RS03525	COG4193	domain, Protein
H7F26_RS03530	COG1482	cell wall glycoprotein biosynthetic process
H7F26_RS03550	COG0800	Aldolase
H7F26_RS03555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H7F26_RS03560	COG1609	Transcriptional regulator
H7F26_RS03565	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
H7F26_RS03570	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_RS03575	COG1063	alcohol dehydrogenase
H7F26_RS03585	COG2814	Major facilitator Superfamily
H7F26_RS03590	COG1316	TRANSCRIPTIONal
H7F26_RS03595	COG0561	phosphatase activity
H7F26_RS03600	COG0791	NLP P60 protein
H7F26_RS03610	COG2843	Capsule synthesis protein
H7F26_RS03620	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
H7F26_RS03625	COG1609	Transcriptional regulator
H7F26_RS03630	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H7F26_RS03635	COG1869	D-ribose catabolic process
H7F26_RS03640	COG1129	ABC transporter
H7F26_RS03645	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7F26_RS03650	COG1879	ABC-type sugar transport system periplasmic component
H7F26_RS03655	COG3527	Alpha-acetolactate decarboxylase
H7F26_RS03660	COG0028	Belongs to the TPP enzyme family
H7F26_RS03665	COG0583	DNA-binding transcription factor activity
H7F26_RS03675	COG0405	Gamma-glutamyltransferase
H7F26_RS03680	COG1522	sequence-specific DNA binding
H7F26_RS03685	COG2059	Chromate
H7F26_RS03690	COG2059	Chromate
H7F26_RS03695	COG4464	protein tyrosine phosphatase activity
H7F26_RS03700	COG3944	biosynthesis protein
H7F26_RS03710	COG4715	Zinc finger, swim domain protein
H7F26_RS03715	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
H7F26_RS03725	COG0561	phosphatase activity
H7F26_RS03730	COG1349	DNA-binding transcription factor activity
H7F26_RS03740	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_RS03750	COG3732	PTS system glucitol sorbitol-specific
H7F26_RS03770	COG0629	single-stranded DNA binding
H7F26_RS03785	COG1970	mechanosensitive ion channel activity
H7F26_RS03790	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H7F26_RS03795	COG4786	Flagellar basal body rod
H7F26_RS03800	COG4786	Flagellar basal body rod
H7F26_RS03805	COG1077	Cell shape determining protein MreB Mrl
H7F26_RS03810	COG1609	Transcriptional regulator
H7F26_RS03815	COG1846	Transcriptional regulator
H7F26_RS03820	COG2814	Major facilitator Superfamily
H7F26_RS03825	COG0671	phosphoesterase, PA-phosphatase related
H7F26_RS03830	COG1227	inorganic diphosphatase activity
H7F26_RS03835	COG3546	catalase activity
H7F26_RS03840	COG3361	conserved protein (COG2071)
H7F26_RS03845	COG0517	IMP dehydrogenase activity
H7F26_RS03850	COG0598	Magnesium transport protein CorA
H7F26_RS03855	COG1253	flavin adenine dinucleotide binding
H7F26_RS03860	COG0004	ammonium transporteR
H7F26_RS03865	COG0347	Belongs to the P(II) protein family
H7F26_RS03870	COG0740	serine-type endopeptidase activity
H7F26_RS03880	COG0739	heme binding
H7F26_RS03885	COG1247	-acetyltransferase
H7F26_RS03895	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7F26_RS03905	COG0477	Major facilitator Superfamily
H7F26_RS03910	COG3251	PFAM MbtH domain protein
H7F26_RS03915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7F26_RS03920	COG1535	isochorismatase
H7F26_RS03920	COG3433	isochorismatase activity
H7F26_RS03925	COG1021	2,3-dihydroxybenzoate-AMP ligase
H7F26_RS03930	COG1169	isochorismate synthase
H7F26_RS03935	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_RS03940	COG2819	hydrolase of the alpha beta superfamily
H7F26_RS03945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F26_RS03950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F26_RS03955	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H7F26_RS03960	COG2207	Transcriptional regulator
H7F26_RS03960	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H7F26_RS03970	COG2910	NAD(P)H-binding
H7F26_RS03975	COG1959	2 iron, 2 sulfur cluster binding
H7F26_RS03985	COG1994	Peptidase M50
H7F26_RS03990	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H7F26_RS03995	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H7F26_RS04000	COG2223	nitrite transmembrane transporter activity
H7F26_RS04005	COG3383	formate dehydrogenase (NAD+) activity
H7F26_RS04010	COG2304	oxidoreductase activity
H7F26_RS04015	COG2304	oxidoreductase activity
H7F26_RS04020	COG2385	sporulation resulting in formation of a cellular spore
H7F26_RS04025	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H7F26_RS04035	COG4836	Membrane
H7F26_RS04040	COG0355	proton-transporting ATP synthase activity, rotational mechanism
H7F26_RS04045	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
H7F26_RS04050	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
H7F26_RS04055	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
H7F26_RS04060	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
H7F26_RS04065	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
H7F26_RS04070	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
H7F26_RS04085	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
H7F26_RS04090	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
H7F26_RS04095	COG4475	Protein of unknown function (DUF436)
H7F26_RS04100	COG0698	ribose 5-phosphate isomerase
H7F26_RS04105	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H7F26_RS04110	COG1971	Probably functions as a manganese efflux pump
H7F26_RS04115	COG0009	L-threonylcarbamoyladenylate synthase
H7F26_RS04120	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
H7F26_RS04130	COG0738	Major facilitator superfamily
H7F26_RS04135	COG0673	inositol 2-dehydrogenase activity
H7F26_RS04140	COG0561	phosphatase activity
H7F26_RS04145	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H7F26_RS04150	COG1609	Transcriptional regulator
H7F26_RS04155	COG2890	protein-(glutamine-N5) methyltransferase activity
H7F26_RS04160	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
H7F26_RS04165	COG0346	lactoylglutathione lyase activity
H7F26_RS04170	COG0789	Transcriptional regulator
H7F26_RS04175	COG0679	Auxin Efflux Carrier
H7F26_RS04180	COG0281	malic enzyme
H7F26_RS04185	COG1435	thymidine kinase activity
H7F26_RS04190	COG0254	rRNA binding
H7F26_RS04195	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
H7F26_RS04200	COG1494	fructose-1,6-bisphosphatase
H7F26_RS04205	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H7F26_RS04210	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H7F26_RS04215	COG0191	fructose-bisphosphate aldolase activity
H7F26_RS04220	COG2204	response regulator
H7F26_RS04225	COG4821	SIS domain
H7F26_RS04235	COG0504	CTP synthase activity
H7F26_RS04240	COG3343	RNA polymerase activity
H7F26_RS04250	COG1960	acyl-CoA dehydrogenase activity
H7F26_RS04255	COG1960	acyl-CoA dehydrogenase activity
H7F26_RS04260	COG1250	3-hydroxyacyl-CoA dehydrogenase
H7F26_RS04265	COG0183	Belongs to the thiolase family
H7F26_RS04270	COG0247	lactate metabolic process
H7F26_RS04270	COG2181	nitrate reductase activity
H7F26_RS04275	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7F26_RS04285	COG0018	arginyl-trna synthetase
H7F26_RS04290	COG4506	Protein conserved in bacteria
H7F26_RS04295	COG0010	Belongs to the arginase family
H7F26_RS04300	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
H7F26_RS04315	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H7F26_RS04325	COG1994	Peptidase M50
H7F26_RS04330	COG1942	4-Oxalocrotonate Tautomerase
H7F26_RS04340	COG3465	dGTPase activity
H7F26_RS04345	COG1078	dGTPase activity
H7F26_RS04350	COG4844	belongs to the
H7F26_RS04375	COG2814	Major facilitator Superfamily
H7F26_RS04400	COG1414	Transcriptional regulator
H7F26_RS04410	COG0280	phosphate acetyltransferase
H7F26_RS04415	COG3253	May function as heme-dependent peroxidase
H7F26_RS04425	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H7F26_RS04445	COG1131	(ABC) transporter
H7F26_RS04460	COG2363	Small membrane protein
H7F26_RS04465	COG2233	PERMEase
H7F26_RS04475	COG1012	belongs to the aldehyde dehydrogenase family
H7F26_RS04480	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
H7F26_RS04485	COG1216	Glycosyl transferase, family 2
H7F26_RS04490	COG0351	phosphomethylpyrimidine kinase
H7F26_RS04500	COG1621	beta-fructofuranosidase activity
H7F26_RS04505	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F26_RS04505	COG1263	PTS System
H7F26_RS04510	COG3711	transcriptional antiterminator
H7F26_RS04520	COG1404	Belongs to the peptidase S8 family
H7F26_RS04530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7F26_RS04535	COG0778	Nitroreductase
H7F26_RS04540	COG1473	amidohydrolase
H7F26_RS04545	COG0772	Belongs to the SEDS family
H7F26_RS04550	COG0772	Belongs to the SEDS family
H7F26_RS04555	COG3314	Sporulation integral membrane protein YlbJ
H7F26_RS04570	COG0456	acetyltransferase
H7F26_RS04605	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H7F26_RS04615	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H7F26_RS04620	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H7F26_RS04625	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H7F26_RS04640	COG3162	membrane
H7F26_RS04645	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H7F26_RS04650	COG1070	Carbohydrate kinase
H7F26_RS04655	COG2115	Belongs to the xylose isomerase family
H7F26_RS04665	COG0352	thiamine-phosphate diphosphorylase activity
H7F26_RS04670	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
H7F26_RS04675	COG0583	DNA-binding transcription factor activity
H7F26_RS04690	COG1380	Effector of murein hydrolase LrgA
H7F26_RS04695	COG1346	cytolysis
H7F26_RS04705	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H7F26_RS04710	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
H7F26_RS04715	COG0346	lactoylglutathione lyase activity
H7F26_RS04720	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H7F26_RS04725	COG1442	glycosyl transferase family 8
H7F26_RS04735	COG4585	Histidine kinase
H7F26_RS04740	COG2197	response regulator
H7F26_RS04745	COG2409	Drug exporters of the RND superfamily
H7F26_RS04750	COG5522	Integral membrane protein (intg_mem_TP0381)
H7F26_RS04755	COG2271	Major facilitator Superfamily
H7F26_RS04760	COG4948	Mandelate Racemase Muconate Lactonizing
H7F26_RS04765	COG0800	Aldolase
H7F26_RS04770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H7F26_RS04780	COG2234	aminopeptidase activity
H7F26_RS04785	COG0477	Major facilitator Superfamily
H7F26_RS04795	COG2357	RelA SpoT domain protein
H7F26_RS04810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7F26_RS04815	COG1696	Membrane protein involved in D-alanine export
H7F26_RS04820	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H7F26_RS04825	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
H7F26_RS04830	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H7F26_RS04835	COG2814	Major facilitator Superfamily
H7F26_RS04840	COG1486	melibiose metabolic process
H7F26_RS04845	COG1447	Phosphotransferase system cellobiose-specific component IIA
H7F26_RS04850	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7F26_RS04855	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7F26_RS04860	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F26_RS04860	COG3711	transcriptional antiterminator
H7F26_RS04865	COG2094	Belongs to the DNA glycosylase MPG family
H7F26_RS04875	COG0372	Belongs to the citrate synthase family
H7F26_RS04880	COG2079	MmgE PrpD family protein
H7F26_RS04885	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
H7F26_RS04900	COG1132	(ABC) transporter
H7F26_RS04905	COG2755	lipolytic protein G-D-S-L family
H7F26_RS04920	COG2814	Major facilitator Superfamily
H7F26_RS04925	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
H7F26_RS04930	COG1131	(ABC) transporter
H7F26_RS04950	COG1595	DNA-templated transcription, initiation
H7F26_RS04955	COG2814	Major facilitator Superfamily
H7F26_RS04960	COG0753	catalase activity
H7F26_RS04965	COG0753	catalase activity
H7F26_RS04970	COG0735	belongs to the Fur family
H7F26_RS04975	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
H7F26_RS04980	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
H7F26_RS04985	COG1131	(ABC) transporter
H7F26_RS05000	COG1131	(ABC) transporter
H7F26_RS05055	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H7F26_RS05060	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
H7F26_RS05065	COG4988	ABC transporter
H7F26_RS05070	COG1294	oxidase, subunit
H7F26_RS05075	COG1271	oxidase subunit
H7F26_RS05080	COG2116	formate transmembrane transporter activity
H7F26_RS05090	COG0281	malic enzyme
H7F26_RS05095	COG1757	Na H antiporter
H7F26_RS05100	COG1027	Aspartate ammonia-lyase
H7F26_RS05105	COG0252	asparaginase activity
H7F26_RS05110	COG1396	sequence-specific DNA binding
H7F26_RS05115	COG2706	6-phosphogluconolactonase activity
H7F26_RS05120	COG0745	RESPONSE REGULATOR receiver
H7F26_RS05125	COG2205	protein histidine kinase activity
H7F26_RS05130	COG1136	(ABC) transporter
H7F26_RS05135	COG0577	efflux transmembrane transporter activity
H7F26_RS05140	COG5294	Protein conserved in bacteria
H7F26_RS05155	COG0726	polysaccharide deacetylase
H7F26_RS05160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7F26_RS05170	COG3493	citrate carrier protein
H7F26_RS05175	COG0584	glycerophosphoryl diester phosphodiesterase
H7F26_RS05190	COG1368	sulfuric ester hydrolase activity
H7F26_RS05200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H7F26_RS05210	COG2235	arginine
H7F26_RS05215	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
H7F26_RS05225	COG0549	Belongs to the carbamate kinase family
H7F26_RS05240	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7F26_RS05250	COG1595	DNA-templated transcription, initiation
H7F26_RS05275	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H7F26_RS05280	COG2195	Cleaves the N-terminal amino acid of tripeptides
H7F26_RS05285	COG1621	beta-fructofuranosidase activity
H7F26_RS05290	COG2223	nitrite transmembrane transporter activity
H7F26_RS05295	COG1609	Transcriptional regulator
H7F26_RS05310	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
H7F26_RS05315	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
H7F26_RS05320	COG0463	Glycosyl transferase, family 2
H7F26_RS05325	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H7F26_RS05350	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H7F26_RS05365	COG2723	6-phospho-beta-galactosidase activity
H7F26_RS05370	COG2190	(PTS) system
H7F26_RS05370	COG1263	PTS System
H7F26_RS05370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F26_RS05375	COG3711	transcriptional antiterminator
H7F26_RS05380	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
H7F26_RS05385	COG1122	ATPase activity
H7F26_RS05390	COG4721	ABC-type cobalt transport system, permease component
H7F26_RS05395	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H7F26_RS05405	COG2224	Isocitrate lyase
H7F26_RS05410	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H7F26_RS05420	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
H7F26_RS05425	COG0577	efflux transmembrane transporter activity
H7F26_RS05430	COG1136	(ABC) transporter
H7F26_RS05435	COG2205	protein histidine kinase activity
H7F26_RS05440	COG0745	RESPONSE REGULATOR receiver
H7F26_RS05445	COG2723	6-phospho-beta-galactosidase activity
H7F26_RS05450	COG2190	(PTS) system
H7F26_RS05450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F26_RS05450	COG1263	PTS System
H7F26_RS05460	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
H7F26_RS05465	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
H7F26_RS05470	COG3507	Belongs to the glycosyl hydrolase 43 family
H7F26_RS05475	COG0513	Belongs to the DEAD box helicase family
H7F26_RS05505	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
H7F26_RS05510	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H7F26_RS05515	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
H7F26_RS05520	COG2390	Transcriptional regulator
H7F26_RS05530	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
H7F26_RS05535	COG3706	GGDEF domain
H7F26_RS05540	COG5298	Protein conserved in bacteria
H7F26_RS05545	COG1215	transferase activity, transferring glycosyl groups
H7F26_RS05555	COG3977	Valine--pyruvate aminotransferase
H7F26_RS05570	COG1181	Belongs to the D-alanine--D-alanine ligase family
H7F26_RS05580	COG0191	fructose-bisphosphate aldolase activity
H7F26_RS05585	COG1082	Xylose isomerase domain protein TIM barrel
H7F26_RS05590	COG1082	Xylose isomerase domain protein TIM barrel
H7F26_RS05595	COG0673	inositol 2-dehydrogenase activity
H7F26_RS05600	COG2814	Major facilitator Superfamily
H7F26_RS05605	COG1082	Xylose isomerase domain protein TIM barrel
H7F26_RS05610	COG3962	Belongs to the TPP enzyme family
H7F26_RS05615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H7F26_RS05620	COG3718	enzyme involved in inositol metabolism
H7F26_RS05625	COG1012	belongs to the aldehyde dehydrogenase family
H7F26_RS05630	COG1349	DNA-binding transcription factor activity
H7F26_RS05635	COG0667	Aldo Keto reductase
H7F26_RS05640	COG0584	glycerophosphoryl diester phosphodiesterase
H7F26_RS05645	COG2271	Major facilitator Superfamily
H7F26_RS05650	COG0326	Molecular chaperone. Has ATPase activity
H7F26_RS05655	COG0488	(ABC) transporter
H7F26_RS05660	COG0561	phosphatase activity
H7F26_RS05680	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H7F26_RS05710	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
H7F26_RS05715	COG0577	efflux transmembrane transporter activity
H7F26_RS05720	COG1136	(ABC) transporter
H7F26_RS05725	COG2205	protein histidine kinase activity
H7F26_RS05730	COG0745	RESPONSE REGULATOR receiver
H7F26_RS05740	COG5278	phosphoserine phosphatase activity
H7F26_RS05740	COG0840	transmembrane signaling receptor activity
H7F26_RS05745	COG1115	amino acid carrier protein
H7F26_RS05750	COG0686	Belongs to the AlaDH PNT family
H7F26_RS05755	COG3867	Arabinogalactan endo-beta-1,4-galactanase
H7F26_RS05760	COG1874	Beta-galactosidase
H7F26_RS05765	COG3833	ABC-type maltose transport systems, permease component
H7F26_RS05770	COG1175	transmembrane transport
H7F26_RS05775	COG2182	Extracellular solute-binding protein
H7F26_RS05780	COG1609	Transcriptional regulator
H7F26_RS05790	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H7F26_RS05795	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
H7F26_RS05800	COG1940	carbohydrate kinase activity
H7F26_RS05825	COG1454	alcohol dehydrogenase
H7F26_RS05825	COG1012	belongs to the aldehyde dehydrogenase family
H7F26_RS05830	COG0450	alkyl hydroperoxide reductase
H7F26_RS05835	COG3634	alkyl hydroperoxide reductase activity
H7F26_RS05860	COG1131	(ABC) transporter
H7F26_RS05865	COG0842	Transport permease protein
H7F26_RS05870	COG4585	Histidine kinase
H7F26_RS05875	COG2197	response regulator
H7F26_RS05905	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
H7F26_RS05920	COG0456	acetyltransferase
H7F26_RS05935	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7F26_RS05940	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
H7F26_RS05945	COG4853	Protein conserved in bacteria
H7F26_RS05950	COG4863	YycH protein
H7F26_RS05955	COG5002	protein histidine kinase activity
H7F26_RS05960	COG0745	RESPONSE REGULATOR receiver
H7F26_RS05985	COG1051	belongs to the nudix hydrolase family
H7F26_RS05990	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H7F26_RS06000	COG0305	Participates in initiation and elongation during chromosome replication
H7F26_RS06015	COG3093	addiction module antidote protein HigA
H7F26_RS06020	COG2807	transmembrane transport
H7F26_RS06025	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
H7F26_RS06030	COG0363	glucosamine-6-phosphate deaminase activity
H7F26_RS06035	COG2188	Transcriptional regulator
H7F26_RS06040	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
H7F26_RS06045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F26_RS06045	COG1263	PTS System
H7F26_RS06050	COG0359	binds to the 23S rRNA
H7F26_RS06055	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
H7F26_RS06060	COG4241	membrane
H7F26_RS06070	COG5577	PFAM Coat F domain
H7F26_RS06075	COG0589	response to stress
H7F26_RS06080	COG0659	secondary active sulfate transmembrane transporter activity
H7F26_RS06085	COG2271	Major facilitator Superfamily
H7F26_RS06090	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
H7F26_RS06095	COG0629	single-stranded DNA binding
H7F26_RS06100	COG0360	Binds together with S18 to 16S ribosomal RNA
H7F26_RS06105	COG0012	GTP binding
H7F26_RS06110	COG4481	Protein conserved in bacteria
H7F26_RS06115	COG3949	Membrane
H7F26_RS06125	COG1475	DNA binding
H7F26_RS06130	COG1192	Involved in chromosome partitioning
H7F26_RS06135	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H7F26_RS06145	COG1475	DNA binding
H7F26_RS06150	COG0357	Ribosomal RNA small subunit methyltransferase G
H7F26_RS06155	COG0445	tRNA wobble uridine modification
H7F26_RS06160	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
H7F26_RS06165	COG1847	R3H domain protein
H7F26_RS06170	COG0706	membrane insertase activity
H7F26_RS06175	COG0594	ribonuclease P activity
H7F26_RS06185	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
H7F26_RS06190	COG0592	DNA-directed DNA polymerase activity
H7F26_RS06195	COG2501	S4 domain
H7F26_RS06200	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
H7F26_RS06210	COG0187	DNA topoisomerase II activity
H7F26_RS06215	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H7F26_RS06250	COG0516	GMP reductase activity
H7F26_RS06250	COG0517	IMP dehydrogenase activity
H7F26_RS06255	COG1686	Belongs to the peptidase S11 family
H7F26_RS06260	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
H7F26_RS06265	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
H7F26_RS06270	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
H7F26_RS06275	COG1929	Belongs to the glycerate kinase type-1 family
H7F26_RS06280	COG2610	gluconate transmembrane transporter activity
H7F26_RS06285	COG3835	regulator
H7F26_RS06300	COG1428	Deoxynucleoside kinase
H7F26_RS06305	COG1428	Deoxynucleoside kinase
H7F26_RS06310	COG3858	chitin binding
H7F26_RS06310	COG1388	LysM domain
H7F26_RS06315	COG1335	isochorismatase
H7F26_RS06320	COG0590	tRNA wobble adenosine to inosine editing
H7F26_RS06330	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H7F26_RS06335	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
H7F26_RS06340	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H7F26_RS06385	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
H7F26_RS06390	COG3853	Toxic anion resistance protein (TelA)
H7F26_RS06395	COG1982	Orn Lys Arg decarboxylase major
H7F26_RS06400	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
H7F26_RS06405	COG3870	Protein conserved in bacteria
H7F26_RS06410	COG1728	Protein conserved in bacteria
H7F26_RS06415	COG0470	DNA polymerase III
H7F26_RS06420	COG1774	PSP1 C-terminal conserved region
H7F26_RS06425	COG4467	Involved in initiation control of chromosome replication
H7F26_RS06430	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
H7F26_RS06435	COG2827	Endonuclease containing a URI domain
H7F26_RS06440	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
H7F26_RS06445	COG2002	toxin-antitoxin pair type II binding
H7F26_RS06450	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7F26_RS06450	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7F26_RS06455	COG0084	hydrolase, TatD family'
H7F26_RS06460	COG3584	3D domain protein
H7F26_RS06460	COG3583	domain protein
H7F26_RS06465	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
H7F26_RS06470	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H7F26_RS06480	COG4466	Protein conserved in bacteria
H7F26_RS06490	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
H7F26_RS06495	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
H7F26_RS06500	COG0251	oxidation-reduction process
H7F26_RS06505	COG2088	sporulation resulting in formation of a cellular spore
H7F26_RS06510	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
H7F26_RS06515	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H7F26_RS06520	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
H7F26_RS06525	COG0193	aminoacyl-tRNA hydrolase activity
H7F26_RS06535	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H7F26_RS06540	COG2002	toxin-antitoxin pair type II binding
H7F26_RS06545	COG2244	polysaccharide biosynthetic process
H7F26_RS06550	COG3956	TIGRFAM MazG family protein
H7F26_RS06555	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H7F26_RS06570	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H7F26_RS06575	COG1098	S1 RNA binding domain
H7F26_RS06590	COG2208	phosphoserine phosphatase activity
H7F26_RS06595	COG2304	oxidoreductase activity
H7F26_RS06600	COG0515	serine threonine protein kinase
H7F26_RS06605	COG0037	tRNA processing
H7F26_RS06610	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
H7F26_RS06615	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H7F26_RS06620	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
H7F26_RS06625	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
H7F26_RS06630	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H7F26_RS06635	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H7F26_RS06640	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H7F26_RS06645	COG0512	Glutamine amidotransferase of anthranilate synthase
H7F26_RS06650	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H7F26_RS06655	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H7F26_RS06660	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H7F26_RS06665	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H7F26_RS06670	COG1396	sequence-specific DNA binding
H7F26_RS06675	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H7F26_RS06680	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
H7F26_RS06760	COG4463	regulation of RNA biosynthetic process
H7F26_RS06765	COG3880	PFAM UvrB UvrC protein
H7F26_RS06770	COG3869	Catalyzes the specific phosphorylation of arginine residues in
H7F26_RS06775	COG0542	response to heat
H7F26_RS06780	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
H7F26_RS06785	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
H7F26_RS06790	COG4956	integral membrane protein (PIN domain superfamily)
H7F26_RS06795	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
H7F26_RS06800	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
H7F26_RS06805	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H7F26_RS06810	COG1045	serine acetyltransferase
H7F26_RS06815	COG0215	cysteine-tRNA ligase activity
H7F26_RS06820	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
H7F26_RS06825	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H7F26_RS06830	COG3688	RNA-binding protein containing a PIN domain
H7F26_RS06840	COG0267	Belongs to the bacterial ribosomal protein bL33 family
H7F26_RS06850	COG0250	Participates in transcription elongation, termination and antitermination
H7F26_RS06855	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
H7F26_RS06860	COG0081	regulation of translation
H7F26_RS06865	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
H7F26_RS06870	COG0222	ribosome binding
H7F26_RS06875	COG2813	Specifically methylates the guanine in position
H7F26_RS06880	COG0085	RNA polymerase activity
H7F26_RS06885	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
H7F26_RS06890	COG1358	cellular component organization or biogenesis
H7F26_RS06895	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
H7F26_RS06900	COG0049	tRNA binding
H7F26_RS06905	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
H7F26_RS06910	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
H7F26_RS06920	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
H7F26_RS06925	COG0088	Forms part of the polypeptide exit tunnel
H7F26_RS06930	COG0089	rRNA binding
H7F26_RS06935	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
H7F26_RS06940	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
H7F26_RS06945	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
H7F26_RS06950	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
H7F26_RS06955	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
H7F26_RS06960	COG0255	Belongs to the universal ribosomal protein uL29 family
H7F26_RS06965	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
H7F26_RS06970	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
H7F26_RS06975	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
H7F26_RS06980	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
H7F26_RS06985	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
H7F26_RS06990	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
H7F26_RS06995	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
H7F26_RS07000	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
H7F26_RS07005	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
H7F26_RS07010	COG1841	ribosomal large subunit assembly
H7F26_RS07015	COG0200	Binds to the 23S rRNA
H7F26_RS07020	COG0201	protein transport
H7F26_RS07025	COG0563	adenylate kinase activity
H7F26_RS07030	COG0024	Methionine aminopeptidase
H7F26_RS07035	COG2163	COG2163 Ribosomal protein L14E L6E L27E
H7F26_RS07040	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
H7F26_RS07045	COG0257	Belongs to the bacterial ribosomal protein bL36 family
H7F26_RS07050	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
H7F26_RS07055	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
H7F26_RS07060	COG0202	RNA polymerase activity
H7F26_RS07065	COG0203	ribosomal protein L17
H7F26_RS07070	COG1122	ATPase activity
H7F26_RS07075	COG1122	ATPase activity
H7F26_RS07080	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
H7F26_RS07085	COG0101	tRNA pseudouridine synthase activity
H7F26_RS07090	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
H7F26_RS07095	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H7F26_RS07100	COG2318	DinB family
H7F26_RS07110	COG0860	N-Acetylmuramoyl-L-alanine amidase
H7F26_RS07115	COG0489	protein tyrosine kinase activity
H7F26_RS07125	COG2194	sulfuric ester hydrolase activity
H7F26_RS07130	COG0726	polysaccharide deacetylase
H7F26_RS07160	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H7F26_RS07170	COG0385	Bile acid
H7F26_RS07185	COG3876	Protein conserved in bacteria
H7F26_RS07190	COG1472	Belongs to the glycosyl hydrolase 3 family
H7F26_RS07195	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H7F26_RS07200	COG1263	PTS System
H7F26_RS07200	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F26_RS07205	COG1737	Transcriptional regulator
H7F26_RS07210	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
H7F26_RS07215	COG1683	Conserved Protein
H7F26_RS07250	COG1595	DNA-templated transcription, initiation
H7F26_RS07255	COG5662	AntiSigma factor
H7F26_RS07260	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
H7F26_RS07265	COG4856	YbbR-like protein
H7F26_RS07270	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H7F26_RS07275	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H7F26_RS07295	COG1725	Transcriptional regulator
H7F26_RS07300	COG0640	Transcriptional regulator
H7F26_RS07305	COG2814	Major facilitator Superfamily
H7F26_RS07315	COG1132	(ABC) transporter
H7F26_RS07320	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H7F26_RS07345	COG1011	Hydrolase
H7F26_RS07350	COG1113	amino acid transport
H7F26_RS07355	COG2851	Citrate transporter
H7F26_RS07360	COG3181	Tripartite tricarboxylate transporter family receptor
H7F26_RS07365	COG4565	transcriptional regulatory protein
H7F26_RS07370	COG3290	protein histidine kinase activity
H7F26_RS07385	COG2211	Major facilitator Superfamily
H7F26_RS07405	COG1331	Highly conserved protein containing a thioredoxin domain
H7F26_RS07410	COG3677	Transposase
H7F26_RS07445	COG1331	Highly conserved protein containing a thioredoxin domain
H7F26_RS07450	COG0477	Major facilitator Superfamily
H7F26_RS07470	COG1283	sodium-dependent phosphate transmembrane transporter activity
H7F26_RS07475	COG4682	membrane
H7F26_RS07500	COG0697	spore germination
H7F26_RS07505	COG2207	Transcriptional regulator
H7F26_RS07505	COG1917	Cupin 2, conserved barrel domain protein
H7F26_RS07525	COG0371	Dehydrogenase
H7F26_RS07530	COG0840	transmembrane signaling receptor activity
H7F26_RS07535	COG4213	ABC transporter substrate-binding protein
H7F26_RS07550	COG4257	antibiotic catabolic process
H7F26_RS07560	COG0833	amino acid
H7F26_RS07565	COG2040	homocysteine
H7F26_RS07575	COG2190	(PTS) system
H7F26_RS07575	COG1263	PTS System
H7F26_RS07575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F26_RS07580	COG0789	Transcriptional regulator
H7F26_RS07585	COG2323	membrane
H7F26_RS07590	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H7F26_RS07590	COG4451	ribulose bisphosphate carboxylase, small
H7F26_RS07595	COG2205	protein histidine kinase activity
H7F26_RS07600	COG1115	amino acid carrier protein
H7F26_RS07605	COG2066	Belongs to the glutaminase family
H7F26_RS07610	COG4191	Histidine kinase
H7F26_RS07615	COG0784	Response regulator, receiver
H7F26_RS07640	COG3540	Alkaline phosphatase
H7F26_RS07645	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H7F26_RS07650	COG0805	protein transport
H7F26_RS07655	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H7F26_RS07660	COG1012	belongs to the aldehyde dehydrogenase family
H7F26_RS07665	COG2271	Major facilitator Superfamily
H7F26_RS07670	COG4948	Mandelate Racemase Muconate Lactonizing
H7F26_RS07675	COG2186	Transcriptional regulator
H7F26_RS07680	COG2721	sulfolactate sulfo-lyase activity
H7F26_RS07685	COG0745	RESPONSE REGULATOR receiver
H7F26_RS07690	COG2205	protein histidine kinase activity
H7F26_RS07695	COG1131	(ABC) transporter
H7F26_RS07720	COG3173	Aminoglycoside phosphotransferase
H7F26_RS07725	COG1846	Transcriptional regulator
H7F26_RS07730	COG0318	PFAM AMP-dependent synthetase and ligase
H7F26_RS07750	COG0789	Transcriptional regulator
H7F26_RS07775	COG0697	spore germination
H7F26_RS07780	COG1714	RDD family
H7F26_RS07785	COG1405	negative regulation of cell septum assembly
H7F26_RS07785	COG3012	SEC-C Motif Domain Protein
H7F26_RS07790	COG1131	(ABC) transporter
H7F26_RS07820	COG1942	4-Oxalocrotonate Tautomerase
H7F26_RS07825	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_RS07840	COG1288	antiporter activity
H7F26_RS07850	COG0456	acetyltransferase
H7F26_RS07860	COG1164	Oligoendopeptidase f
H7F26_RS07865	COG2261	transglycosylase associated protein
H7F26_RS07875	COG0247	lactate metabolic process
H7F26_RS07880	COG0277	FAD linked oxidase domain protein
H7F26_RS07885	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7F26_RS07890	COG1447	Phosphotransferase system cellobiose-specific component IIA
H7F26_RS07895	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7F26_RS07900	COG1486	melibiose metabolic process
H7F26_RS07905	COG2188	Transcriptional regulator
H7F26_RS07910	COG3394	polysaccharide catabolic process
H7F26_RS07925	COG3591	Belongs to the peptidase S1B family
H7F26_RS07930	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_RS07940	COG1595	DNA-templated transcription, initiation
H7F26_RS07950	COG3773	Cell wall hydrolase
H7F26_RS07955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7F26_RS07960	COG3883	PFAM NLP P60 protein
H7F26_RS07960	COG0791	NLP P60 protein
H7F26_RS07970	COG1131	(ABC) transporter
H7F26_RS07975	COG1309	transcriptional regulator
H7F26_RS07995	COG2310	stress, protein
H7F26_RS08000	COG2310	stress, protein
H7F26_RS08005	COG2310	stress, protein
H7F26_RS08010	COG0861	Integral membrane protein TerC family
H7F26_RS08030	COG3853	Toxic anion resistance protein (TelA)
H7F26_RS08035	COG0785	Cytochrome C biogenesis protein
H7F26_RS08045	COG0789	Transcriptional regulator
H7F26_RS08050	COG2223	nitrite transmembrane transporter activity
H7F26_RS08055	COG0039	L-malate dehydrogenase activity
H7F26_RS08060	COG1620	l-lactate permease
H7F26_RS08065	COG1280	lysine exporter protein (LysE YggA)
H7F26_RS08070	COG1113	amino acid transport
H7F26_RS08075	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H7F26_RS08080	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
H7F26_RS08085	COG3541	Predicted nucleotidyltransferase
H7F26_RS08090	COG0506	proline dehydrogenase activity
H7F26_RS08095	COG1012	belongs to the aldehyde dehydrogenase family
H7F26_RS08100	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H7F26_RS08105	COG2508	Transcriptional regulator
H7F26_RS08110	COG3689	TIGRFAM TIGR03943 family protein
H7F26_RS08115	COG0701	Predicted permease
H7F26_RS08120	COG3458	cephalosporin-C deacetylase activity
H7F26_RS08140	COG0765	amino acid transport
H7F26_RS08145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F26_RS08150	COG2249	NAD(P)H dehydrogenase (quinone) activity
H7F26_RS08160	COG2723	6-phospho-beta-galactosidase activity
H7F26_RS08170	COG3209	COG3209 Rhs family protein
H7F26_RS08180	COG3266	domain, Protein
H7F26_RS08180	COG0515	serine threonine protein kinase
H7F26_RS08190	COG5444	nuclease activity
H7F26_RS08215	COG1176	ABC-type spermidine putrescine transport system, permease component I
H7F26_RS08220	COG1177	transmembrane transport
H7F26_RS08225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7F26_RS08230	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7F26_RS08235	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
H7F26_RS08240	COG0697	spore germination
H7F26_RS08245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7F26_RS08255	COG2819	hydrolase of the alpha beta superfamily
H7F26_RS08265	COG2364	Membrane
H7F26_RS08275	COG1131	(ABC) transporter
H7F26_RS08305	COG1126	abc transporter atp-binding protein
H7F26_RS08310	COG0765	amino acid transport
H7F26_RS08315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F26_RS08320	COG3829	transcription factor binding
H7F26_RS08325	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H7F26_RS08330	COG0833	amino acid
H7F26_RS08335	COG0010	Belongs to the arginase family
H7F26_RS08340	COG0583	DNA-binding transcription factor activity
H7F26_RS08345	COG0163	prenyltransferase activity
H7F26_RS08350	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
H7F26_RS08395	COG5444	nuclease activity
H7F26_RS08415	COG2972	Histidine kinase
H7F26_RS08420	COG2207	Transcriptional regulator
H7F26_RS08420	COG4753	response regulator
H7F26_RS08425	COG4213	ABC transporter substrate-binding protein
H7F26_RS08435	COG4214	carbohydrate transport
H7F26_RS08440	COG2271	Major facilitator Superfamily
H7F26_RS08445	COG0456	acetyltransferase
H7F26_RS08445	COG1846	Transcriptional regulator
H7F26_RS08455	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
H7F26_RS08460	COG3104	oligopeptide transport
H7F26_RS08465	COG5434	Belongs to the glycosyl hydrolase 28 family
H7F26_RS08475	COG0697	spore germination
H7F26_RS08485	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H7F26_RS08490	COG0789	Transcriptional regulator
H7F26_RS08495	COG1136	(ABC) transporter
H7F26_RS08500	COG0577	efflux transmembrane transporter activity
H7F26_RS08505	COG0745	RESPONSE REGULATOR receiver
H7F26_RS08510	COG3850	Histidine kinase
H7F26_RS08510	COG5002	protein histidine kinase activity
H7F26_RS08520	COG0527	aspartate kinase activity
H7F26_RS08525	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F26_RS08530	COG4605	iron ion homeostasis
H7F26_RS08535	COG4604	ABC transporter, ATP-binding protein
H7F26_RS08540	COG4607	ABC-type enterochelin transport system periplasmic component
H7F26_RS08545	COG2814	Major facilitator Superfamily
H7F26_RS08550	COG1309	transcriptional regulator
H7F26_RS08560	COG0778	Nitroreductase
H7F26_RS08565	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H7F26_RS08570	COG0640	Transcriptional regulator
H7F26_RS08575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7F26_RS08580	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H7F26_RS08585	COG0531	amino acid
H7F26_RS08590	COG1012	belongs to the aldehyde dehydrogenase family
H7F26_RS08595	COG0697	spore germination
H7F26_RS08605	COG4549	nuclear export factor GLE1
H7F26_RS08610	COG1276	copper resistance
H7F26_RS08610	COG2372	response to copper ion
H7F26_RS08615	COG1349	DNA-binding transcription factor activity
H7F26_RS08620	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H7F26_RS08625	COG0243	molybdopterin cofactor binding
H7F26_RS08630	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H7F26_RS08635	COG2146	nitrite reductase [NAD(P)H] activity
H7F26_RS08640	COG1587	Uroporphyrinogen-III synthase
H7F26_RS08640	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H7F26_RS08645	COG1802	Transcriptional regulator
H7F26_RS08650	COG0471	metal ion transport
H7F26_RS08655	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H7F26_RS08660	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H7F26_RS08670	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F26_RS08685	COG3959	Transketolase, thiamine diphosphate binding domain
H7F26_RS08690	COG3958	Transketolase
H7F26_RS08695	COG0561	phosphatase activity
H7F26_RS08700	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
H7F26_RS08705	COG1914	H( )-stimulated, divalent metal cation uptake system
H7F26_RS08710	COG4336	lyase activity
H7F26_RS08715	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
H7F26_RS08720	COG1984	allophanate hydrolase subunit 2
H7F26_RS08725	COG1414	Transcriptional regulator
H7F26_RS08730	COG2755	lipolytic protein G-D-S-L family
H7F26_RS08735	COG2213	PTS system mannitol-specific
H7F26_RS08740	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F26_RS08745	COG0246	Mannitol dehydrogenase
H7F26_RS08750	COG3711	transcriptional antiterminator
H7F26_RS08755	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_RS08760	COG1917	Cupin 2, conserved barrel domain protein
H7F26_RS08770	COG3871	stress protein (general stress protein 26)
H7F26_RS08785	COG2814	Major facilitator Superfamily
H7F26_RS08795	COG1522	sequence-specific DNA binding
H7F26_RS08800	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H7F26_RS08800	COG0551	DNA topoisomerase type I activity
H7F26_RS08805	COG0531	amino acid
H7F26_RS08810	COG0028	Belongs to the TPP enzyme family
H7F26_RS08815	COG3397	chitin binding
H7F26_RS08825	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7F26_RS08830	COG1914	H( )-stimulated, divalent metal cation uptake system
H7F26_RS08835	COG2261	transglycosylase associated protein
H7F26_RS08840	COG1027	Aspartate ammonia-lyase
H7F26_RS08845	COG1819	glycosyl
H7F26_RS08850	COG4876	unkown
H7F26_RS08855	COG2217	Heavy metal translocating P-type atpase
H7F26_RS08865	COG0662	Cupin 2, conserved barrel domain protein
H7F26_RS08875	COG0628	permease
H7F26_RS08880	COG1301	dicarboxylic acid transport
H7F26_RS08885	COG1131	(ABC) transporter
H7F26_RS08890	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
H7F26_RS08900	COG1960	acyl-CoA dehydrogenase activity
H7F26_RS08915	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F26_RS08920	COG1181	Belongs to the D-alanine--D-alanine ligase family
H7F26_RS08925	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H7F26_RS08935	COG0513	Belongs to the DEAD box helicase family
H7F26_RS08940	COG3402	PFAM membrane-flanked domain
H7F26_RS08945	COG3428	Bacterial PH domain
H7F26_RS08950	COG0705	Rhomboid family
H7F26_RS08955	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
H7F26_RS08960	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H7F26_RS08965	COG0864	Transcriptional regulator
H7F26_RS08970	COG2337	Toxic component of a toxin-antitoxin (TA) module
H7F26_RS08975	COG1366	Belongs to the anti-sigma-factor antagonist family
H7F26_RS08980	COG1366	Belongs to the anti-sigma-factor antagonist family
H7F26_RS08985	COG2172	sigma factor antagonist activity
H7F26_RS08990	COG2208	phosphoserine phosphatase activity
H7F26_RS09000	COG2172	sigma factor antagonist activity
H7F26_RS09005	COG1191	sigma factor activity
H7F26_RS09010	COG2208	phosphoserine phosphatase activity
H7F26_RS09015	COG2183	response to ionizing radiation
H7F26_RS09020	COG1309	transcriptional regulator
H7F26_RS09025	COG2409	Drug exporters of the RND superfamily
H7F26_RS09025	COG1033	growth of symbiont in host cell
H7F26_RS09035	COG3091	SprT-like family
H7F26_RS09080	COG1476	TRANSCRIPTIONal
H7F26_RS09085	COG3239	Fatty acid desaturase
H7F26_RS09090	COG1278	Cold shock
H7F26_RS09095	COG1063	alcohol dehydrogenase
H7F26_RS09100	COG2364	Membrane
H7F26_RS09105	COG1846	Transcriptional regulator
H7F26_RS09110	COG0456	acetyltransferase
H7F26_RS09115	COG2808	Putative FMN-binding domain
H7F26_RS09125	COG1733	regulation of RNA biosynthetic process
H7F26_RS09130	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H7F26_RS09140	COG0583	DNA-binding transcription factor activity
H7F26_RS09160	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
H7F26_RS09165	COG1113	amino acid transport
H7F26_RS09180	COG1595	DNA-templated transcription, initiation
H7F26_RS09190	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
H7F26_RS09190	COG2755	lipolytic protein G-D-S-L family
H7F26_RS09195	COG2814	Major facilitator Superfamily
H7F26_RS09200	COG2972	Histidine kinase
H7F26_RS09200	COG0745	RESPONSE REGULATOR receiver
H7F26_RS09205	COG3279	Response regulator of the LytR AlgR family
H7F26_RS09215	COG3764	Sortase (surface protein transpeptidase)
H7F26_RS09220	COG2814	Major facilitator Superfamily
H7F26_RS09260	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H7F26_RS09265	COG0802	atpase or kinase
H7F26_RS09270	COG1214	PFAM Peptidase M22, glycoprotease
H7F26_RS09275	COG0456	acetyltransferase
H7F26_RS09280	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
H7F26_RS09285	COG0488	(ABC) transporter
H7F26_RS09290	COG0315	cyclic pyranopterin monophosphate synthase activity
H7F26_RS09295	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
H7F26_RS09300	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H7F26_RS09305	COG0805	protein transport
H7F26_RS09315	COG1266	CAAX protease self-immunity
H7F26_RS09320	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
H7F26_RS09325	COG0459	protein refolding
H7F26_RS09330	COG4974	Belongs to the 'phage' integrase family
H7F26_RS09335	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H7F26_RS09445	COG0582	viral genome integration into host DNA
H7F26_RS09540	COG3953	SLT domain
H7F26_RS09540	COG5280	Phage tail tape measure protein TP901
H7F26_RS09595	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H7F26_RS09615	COG2720	vancomycin resistance protein
H7F26_RS09630	COG2135	peptidase activity
H7F26_RS09640	COG1309	transcriptional regulator
H7F26_RS09645	COG0574	Belongs to the PEP-utilizing enzyme family
H7F26_RS09645	COG3848	Pyruvate phosphate dikinase
H7F26_RS09655	COG3189	MarR family transcriptional regulator
H7F26_RS09660	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
H7F26_RS09665	COG2272	Belongs to the type-B carboxylesterase lipase family
H7F26_RS09670	COG2814	Major facilitator Superfamily
H7F26_RS09675	COG1842	Phage shock protein A
H7F26_RS09680	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H7F26_RS09685	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
H7F26_RS09690	COG4260	virion core protein, lumpy skin disease virus
H7F26_RS09700	COG1378	Sugar-specific transcriptional regulator TrmB
H7F26_RS09705	COG1280	lysine exporter protein (LysE YggA)
H7F26_RS09710	COG3339	Conserved Protein
H7F26_RS09715	COG0772	Belongs to the SEDS family
H7F26_RS09740	COG0726	polysaccharide deacetylase
H7F26_RS09750	COG1609	Transcriptional regulator
H7F26_RS09755	COG0366	Alpha amylase catalytic
H7F26_RS09760	COG2182	Extracellular solute-binding protein
H7F26_RS09765	COG1175	transmembrane transport
H7F26_RS09770	COG3833	ABC-type maltose transport systems, permease component
H7F26_RS09775	COG5521	maltodextrose utilization protein MalA
H7F26_RS09780	COG1554	hydrolase, family 65, central catalytic
H7F26_RS09785	COG0366	Alpha amylase catalytic
H7F26_RS09790	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H7F26_RS09795	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H7F26_RS09800	COG1846	Transcriptional regulator
H7F26_RS09815	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H7F26_RS09820	COG0823	Involved in the tonB-independent uptake of proteins
H7F26_RS09850	COG0702	epimerase
H7F26_RS09860	COG2132	Multicopper oxidase
H7F26_RS09875	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
H7F26_RS09880	COG0714	Associated with various cellular activities
H7F26_RS09885	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
H7F26_RS09890	COG1305	Transglutaminase-like
H7F26_RS09895	COG0519	Catalyzes the synthesis of GMP from XMP
H7F26_RS09895	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H7F26_RS09900	COG2252	PERMEase
H7F26_RS09915	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
H7F26_RS09925	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
H7F26_RS09930	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H7F26_RS09935	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H7F26_RS09940	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
H7F26_RS09945	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H7F26_RS09950	COG0047	phosphoribosylformylglycinamidine synthase activity
H7F26_RS09955	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H7F26_RS09960	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
H7F26_RS09965	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
H7F26_RS09970	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H7F26_RS09975	COG0138	bifunctional purine biosynthesis protein purh
H7F26_RS09980	COG0151	Belongs to the GarS family
H7F26_RS09990	COG2124	cytochrome p450
H7F26_RS10010	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
H7F26_RS10015	COG1470	cell adhesion involved in biofilm formation
H7F26_RS10020	COG4496	protein, YerC YecD
H7F26_RS10025	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
H7F26_RS10030	COG0210	DNA helicase
H7F26_RS10035	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
H7F26_RS10040	COG4851	CamS sex pheromone cAM373 precursor
H7F26_RS10045	COG2188	Transcriptional regulator
H7F26_RS10065	COG1735	metal-dependent hydrolase with the TIM-barrel fold
H7F26_RS10070	COG0626	cystathionine gamma-synthase activity
H7F26_RS10075	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
H7F26_RS10080	COG3457	Alanine racemase
H7F26_RS10085	COG0363	glucosamine-6-phosphate deaminase activity
H7F26_RS10090	COG1285	pathogenesis
H7F26_RS10095	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H7F26_RS10100	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H7F26_RS10105	COG0154	amidase activity
H7F26_RS10110	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H7F26_RS10125	COG4124	Belongs to the glycosyl hydrolase 26 family
H7F26_RS10130	COG1309	transcriptional regulator
H7F26_RS10135	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H7F26_RS10145	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7F26_RS10150	COG1957	nucleoside hydrolase
H7F26_RS10155	COG1597	lipid kinase activity
H7F26_RS10160	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H7F26_RS10170	COG1263	PTS System
H7F26_RS10170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F26_RS10170	COG2190	(PTS) system
H7F26_RS10175	COG2723	6-phospho-beta-galactosidase activity
H7F26_RS10180	COG3711	transcriptional antiterminator
H7F26_RS10185	COG0457	Tetratricopeptide repeat
H7F26_RS10200	COG0217	transcriptional regulatory protein
H7F26_RS10215	COG1012	belongs to the aldehyde dehydrogenase family
H7F26_RS10220	COG0840	transmembrane signaling receptor activity
H7F26_RS10225	COG0471	metal ion transport
H7F26_RS10230	COG0488	(ABC) transporter
H7F26_RS10240	COG1469	GTP cyclohydrolase I activity
H7F26_RS10255	COG0523	cobalamin synthesis protein
H7F26_RS10260	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
H7F26_RS10265	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H7F26_RS10270	COG0156	8-amino-7-oxononanoate synthase activity
H7F26_RS10275	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
H7F26_RS10280	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
H7F26_RS10285	COG2124	cytochrome p450
H7F26_RS10295	COG0789	Transcriptional regulator
H7F26_RS10300	COG2814	Major facilitator Superfamily
H7F26_RS10305	COG0488	(ABC) transporter
H7F26_RS10310	COG0513	Belongs to the DEAD box helicase family
H7F26_RS10315	COG2130	NADP-dependent
H7F26_RS10330	COG0471	metal ion transport
H7F26_RS10350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7F26_RS10360	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
H7F26_RS10365	COG5658	integral membrane protein
H7F26_RS10370	COG0640	Transcriptional regulator
H7F26_RS10375	COG1254	Belongs to the acylphosphatase family
H7F26_RS10380	COG2258	MOSC domain
H7F26_RS10395	COG0024	Methionine aminopeptidase
H7F26_RS10400	COG1368	sulfuric ester hydrolase activity
H7F26_RS10410	COG1115	amino acid carrier protein
H7F26_RS10415	COG1263	PTS System
H7F26_RS10415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F26_RS10420	COG0366	Alpha amylase catalytic
H7F26_RS10425	COG2188	Transcriptional regulator
H7F26_RS10450	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H7F26_RS10455	COG1045	serine acetyltransferase
H7F26_RS10460	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H7F26_RS10470	COG1215	transferase activity, transferring glycosyl groups
H7F26_RS10475	COG0457	Tetratricopeptide repeat
H7F26_RS10475	COG0463	Glycosyl transferase, family 2
H7F26_RS10485	COG0673	inositol 2-dehydrogenase activity
H7F26_RS10495	COG0657	acetylesterase activity
H7F26_RS10500	COG1733	regulation of RNA biosynthetic process
H7F26_RS10505	COG0778	Nitroreductase
H7F26_RS10510	COG0737	Belongs to the 5'-nucleotidase family
H7F26_RS10515	COG0693	protein deglycase activity
H7F26_RS10520	COG4840	Belongs to the UPF0435 family
H7F26_RS10525	COG1115	amino acid carrier protein
H7F26_RS10530	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H7F26_RS10535	COG4980	gas vesicle protein
H7F26_RS10540	COG1295	ribonuclease BN
H7F26_RS10545	COG0477	Major facilitator Superfamily
H7F26_RS10555	COG0387	Pfam Sodium calcium exchanger
H7F26_RS10565	COG0535	radical SAM domain protein
H7F26_RS10575	COG0726	polysaccharide deacetylase
H7F26_RS10580	COG0371	Dehydrogenase
H7F26_RS10590	COG0598	Magnesium transport protein CorA
H7F26_RS10595	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
H7F26_RS10600	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H7F26_RS10605	COG4637	Psort location Cytoplasmic, score
H7F26_RS10630	COG1819	glycosyl
H7F26_RS10640	COG0477	Major facilitator Superfamily
H7F26_RS10645	COG1263	PTS System
H7F26_RS10645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F26_RS10650	COG3711	transcriptional antiterminator
H7F26_RS10655	COG0288	reversible hydration of carbon dioxide
H7F26_RS10660	COG3002	Belongs to the UPF0753 family
H7F26_RS10665	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H7F26_RS10670	COG5609	conserved protein (DUF2294)
H7F26_RS10680	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H7F26_RS10685	COG0022	dehydrogenase e1 component
H7F26_RS10690	COG0508	dehydrogenase complex catalyzes the overall conversion of
H7F26_RS10695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H7F26_RS10700	COG3284	Transcriptional regulator
H7F26_RS10705	COG1742	UPF0060 membrane protein
H7F26_RS10710	COG1486	melibiose metabolic process
H7F26_RS10715	COG1737	Transcriptional regulator
H7F26_RS10720	COG1263	PTS System
H7F26_RS10720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F26_RS10735	COG1733	regulation of RNA biosynthetic process
H7F26_RS10740	COG2259	Doxx family
H7F26_RS10745	COG2514	catechol 2,3-dioxygenase activity
H7F26_RS10755	COG3507	Belongs to the glycosyl hydrolase 43 family
H7F26_RS10760	COG2207	Transcriptional regulator
H7F26_RS10760	COG1917	Cupin 2, conserved barrel domain protein
H7F26_RS10765	COG1653	transport
H7F26_RS10770	COG2249	NAD(P)H dehydrogenase (quinone) activity
H7F26_RS10775	COG1051	belongs to the nudix hydrolase family
H7F26_RS10785	COG0392	lysyltransferase activity
H7F26_RS10785	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
H7F26_RS10790	COG0384	phenazine biosynthesis protein PhzF
H7F26_RS10795	COG0778	Nitroreductase
H7F26_RS10815	COG1090	epimerase
H7F26_RS10820	COG2137	regulation of response to DNA damage stimulus
H7F26_RS10845	COG0463	Glycosyl transferase, family 2
H7F26_RS10855	COG4485	Bacterial membrane protein, YfhO
H7F26_RS10860	COG1988	membrane-bound metal-dependent
H7F26_RS10865	COG1194	a g-specific adenine glycosylase
H7F26_RS10875	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_RS10890	COG3557	Belongs to the UPF0374 family
H7F26_RS10895	COG1132	(ABC) transporter
H7F26_RS10900	COG0444	Belongs to the ABC transporter superfamily
H7F26_RS10905	COG4608	Belongs to the ABC transporter superfamily
H7F26_RS10910	COG0747	negative chemotaxis
H7F26_RS10915	COG0601	transmembrane transport
H7F26_RS10920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7F26_RS10925	COG4129	membrane
H7F26_RS10930	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
H7F26_RS10935	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H7F26_RS10940	COG0735	belongs to the Fur family
H7F26_RS11050	COG4974	Belongs to the 'phage' integrase family
H7F26_RS11060	COG0582	viral genome integration into host DNA
H7F26_RS11180	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
H7F26_RS11190	COG0710	3-dehydroquinate dehydratase activity
H7F26_RS11195	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
H7F26_RS11200	COG1116	anion transmembrane transporter activity
H7F26_RS11205	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7F26_RS11210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7F26_RS11215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7F26_RS11225	COG1476	TRANSCRIPTIONal
H7F26_RS11235	COG1131	(ABC) transporter
H7F26_RS11255	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
H7F26_RS11265	COG3382	B3 4 domain protein
H7F26_RS11270	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H7F26_RS11280	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H7F26_RS11285	COG0789	Transcriptional regulator
H7F26_RS11290	COG1664	Polymer-forming cytoskeletal
H7F26_RS11300	COG2766	serine protein kinase
H7F26_RS11305	COG2718	Belongs to the UPF0229 family
H7F26_RS11315	COG1566	PFAM secretion protein HlyD family protein
H7F26_RS11320	COG2814	Major facilitator Superfamily
H7F26_RS11325	COG0655	NAD(P)H dehydrogenase (quinone) activity
H7F26_RS11335	COG1131	(ABC) transporter
H7F26_RS11340	COG1131	(ABC) transporter
H7F26_RS11345	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
H7F26_RS11350	COG1278	Cold shock
H7F26_RS11355	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H7F26_RS11360	COG2011	ABC-type metal ion transport system permease component
H7F26_RS11365	COG1464	Belongs to the NlpA lipoprotein family
H7F26_RS11370	COG1823	symporter activity
H7F26_RS11395	COG5577	PFAM Coat F domain
H7F26_RS11400	COG5002	protein histidine kinase activity
H7F26_RS11405	COG4085	toxin activity
H7F26_RS11405	COG1525	nuclease
H7F26_RS11405	COG0737	Belongs to the 5'-nucleotidase family
H7F26_RS11410	COG3764	Sortase (surface protein transpeptidase)
H7F26_RS11415	COG0564	pseudouridine synthase activity
H7F26_RS11425	COG0517	IMP dehydrogenase activity
H7F26_RS11430	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H7F26_RS11435	COG3153	acetyltransferase
H7F26_RS11435	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H7F26_RS11440	COG0488	(ABC) transporter
H7F26_RS11445	COG2116	formate transmembrane transporter activity
H7F26_RS11450	COG0679	Auxin Efflux Carrier
H7F26_RS11455	COG0604	alcohol dehydrogenase
H7F26_RS11460	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
H7F26_RS11465	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H7F26_RS11470	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H7F26_RS11475	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
H7F26_RS11480	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H7F26_RS11495	COG4585	Histidine kinase
H7F26_RS11495	COG2203	Gaf domain
H7F26_RS11500	COG2197	response regulator
H7F26_RS11505	COG0431	NADPH-dependent FMN reductase
H7F26_RS11520	COG1959	2 iron, 2 sulfur cluster binding
H7F26_RS11525	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H7F26_RS11525	COG1017	nitric oxide dioxygenase activity
H7F26_RS11530	COG2719	SpoVR family
H7F26_RS11535	COG0791	NLP P60 protein
H7F26_RS11535	COG1388	LysM domain
H7F26_RS11540	COG0583	DNA-binding transcription factor activity
H7F26_RS11545	COG0372	Belongs to the citrate synthase family
H7F26_RS11550	COG2133	pyrroloquinoline quinone binding
H7F26_RS11555	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_RS11560	COG0733	neurotransmitter:sodium symporter activity
H7F26_RS11570	COG3708	Transcriptional regulator
H7F26_RS11570	COG2207	Transcriptional regulator
H7F26_RS11575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7F26_RS11595	COG1595	DNA-templated transcription, initiation
H7F26_RS11600	COG0662	Cupin 2, conserved barrel domain protein
H7F26_RS11605	COG0204	Acyl-transferase
H7F26_RS11610	COG3152	Membrane
H7F26_RS11620	COG1309	transcriptional regulator
H7F26_RS11625	COG1253	flavin adenine dinucleotide binding
H7F26_RS11630	COG0789	Transcriptional regulator
H7F26_RS11635	COG1253	flavin adenine dinucleotide binding
H7F26_RS11655	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
H7F26_RS11660	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
H7F26_RS11665	COG0584	glycerophosphoryl diester phosphodiesterase
H7F26_RS11675	COG0668	transmembrane transport
H7F26_RS11680	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H7F26_RS11690	COG0726	polysaccharide deacetylase
H7F26_RS11700	COG1757	Na H antiporter
H7F26_RS11705	COG2017	converts alpha-aldose to the beta-anomer
H7F26_RS11730	COG0589	response to stress
H7F26_RS11735	COG1132	(ABC) transporter
H7F26_RS11740	COG1132	(ABC) transporter
H7F26_RS11745	COG0702	epimerase
H7F26_RS11765	COG3842	ATPase activity
H7F26_RS11770	COG2508	Transcriptional regulator
H7F26_RS11780	COG0189	ligase activity
H7F26_RS11785	COG0189	ligase activity
H7F26_RS11790	COG4399	Belongs to the UPF0754 family
H7F26_RS11795	COG3679	Belongs to the UPF0342 family
H7F26_RS11800	COG0561	phosphatase activity
H7F26_RS11805	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H7F26_RS11810	COG0475	glutathione-regulated potassium exporter activity
H7F26_RS11815	COG0490	domain, Protein
H7F26_RS11825	COG1024	Enoyl-CoA hydratase
H7F26_RS11830	COG0457	Tetratricopeptide repeat
H7F26_RS11850	COG4152	abc transporter atp-binding protein
H7F26_RS11855	COG1668	transmembrane transport
H7F26_RS11860	COG0420	3'-5' exonuclease activity
H7F26_RS11865	COG4717	serine-type aminopeptidase activity
H7F26_RS11870	COG3481	metal-dependent phosphohydrolase, HD sub domain
H7F26_RS11880	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H7F26_RS11910	COG1846	Transcriptional regulator
H7F26_RS11915	COG4980	gas vesicle protein
H7F26_RS11925	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
H7F26_RS11930	COG0537	adenosine 5'-monophosphoramidase activity
H7F26_RS11935	COG1131	(ABC) transporter
H7F26_RS11940	COG4473	ABC transporter
H7F26_RS11950	COG1473	amidohydrolase
H7F26_RS11955	COG3069	C4-dicarboxylate transmembrane transporter activity
H7F26_RS11960	COG2329	Antibiotic biosynthesis monooxygenase
H7F26_RS11965	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H7F26_RS11970	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
H7F26_RS11975	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
H7F26_RS11980	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
H7F26_RS11985	COG1309	transcriptional regulator
H7F26_RS11990	COG1511	domain protein
H7F26_RS11995	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H7F26_RS12000	COG1363	Peptidase, m42
H7F26_RS12010	COG1301	dicarboxylic acid transport
H7F26_RS12020	COG1234	tRNA 3'-trailer cleavage
H7F26_RS12025	COG0095	Lipoate-protein ligase
H7F26_RS12030	COG0318	PFAM AMP-dependent synthetase and ligase
H7F26_RS12040	COG1396	sequence-specific DNA binding
H7F26_RS12055	COG0501	Belongs to the peptidase M48B family
H7F26_RS12065	COG0697	spore germination
H7F26_RS12070	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
H7F26_RS12075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F26_RS12080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F26_RS12085	COG0406	alpha-ribazole phosphatase activity
H7F26_RS12090	COG0840	transmembrane signaling receptor activity
H7F26_RS12095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H7F26_RS12095	COG0723	plastoquinol--plastocyanin reductase activity
H7F26_RS12100	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_RS12110	COG4903	ComK protein
H7F26_RS12120	COG0398	Pfam SNARE associated Golgi protein
H7F26_RS12125	COG0681	Belongs to the peptidase S26 family
H7F26_RS12130	COG1404	Belongs to the peptidase S8 family
H7F26_RS12140	COG2508	Transcriptional regulator
H7F26_RS12150	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
H7F26_RS12155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H7F26_RS12160	COG3257	ureidoglycine aminohydrolase activity
H7F26_RS12165	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
H7F26_RS12170	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
H7F26_RS12175	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H7F26_RS12180	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H7F26_RS12195	COG2814	Major facilitator Superfamily
H7F26_RS12205	COG0457	Tetratricopeptide repeat
H7F26_RS12225	COG1609	Transcriptional regulator
H7F26_RS12230	COG1653	transport
H7F26_RS12235	COG1175	transmembrane transport
H7F26_RS12240	COG0395	ABC-type sugar transport system, permease component
H7F26_RS12245	COG1486	melibiose metabolic process
H7F26_RS12250	COG3180	Ammonia monooxygenase
H7F26_RS12265	COG3546	catalase activity
H7F26_RS12270	COG0318	PFAM AMP-dependent synthetase and ligase
H7F26_RS12275	COG2814	Major facilitator Superfamily
H7F26_RS12275	COG0477	Major facilitator Superfamily
H7F26_RS12285	COG5002	protein histidine kinase activity
H7F26_RS12290	COG0745	RESPONSE REGULATOR receiver
H7F26_RS12295	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
H7F26_RS12300	COG0725	ABC transporter, periplasmic molybdate-binding protein
H7F26_RS12305	COG4149	molybdate abc transporter
H7F26_RS12310	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
H7F26_RS12315	COG1074	ATP-dependent DNA helicase activity
H7F26_RS12320	COG0420	3'-5' exonuclease activity
H7F26_RS12325	COG0419	ATPase involved in DNA repair
H7F26_RS12370	COG5337	Spore coat protein CotH
H7F26_RS12380	COG0179	Fumarylacetoacetate (FAA) hydrolase
H7F26_RS12400	COG0367	asparagine synthase
H7F26_RS12415	COG0534	Mate efflux family protein
H7F26_RS12420	COG2207	Transcriptional regulator
H7F26_RS12420	COG1917	Cupin 2, conserved barrel domain protein
H7F26_RS12430	COG1609	Transcriptional regulator
H7F26_RS12435	COG0673	inositol 2-dehydrogenase activity
H7F26_RS12440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7F26_RS12450	COG0076	glutamate decarboxylase activity
H7F26_RS12475	COG2153	protein acetylation
H7F26_RS12480	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_RS12485	COG2378	regulation of single-species biofilm formation
H7F26_RS12490	COG0646	methionine synthase
H7F26_RS12490	COG1410	methionine synthase
H7F26_RS12495	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H7F26_RS12495	COG0646	methionine synthase
H7F26_RS12500	COG1666	GTP binding
H7F26_RS12505	COG2996	Protein conserved in bacteria
H7F26_RS12520	COG1307	EDD domain protein, DegV family
H7F26_RS12525	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H7F26_RS12535	COG0516	GMP reductase activity
H7F26_RS12550	COG0561	phosphatase activity
H7F26_RS12555	COG1073	alpha beta
H7F26_RS12560	COG2151	metal-sulfur cluster biosynthetic enzyme
H7F26_RS12565	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
H7F26_RS12570	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
H7F26_RS12575	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
H7F26_RS12580	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H7F26_RS12585	COG0505	Belongs to the CarA family
H7F26_RS12590	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
H7F26_RS12595	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
H7F26_RS12600	COG1968	undecaprenyl-diphosphatase activity
H7F26_RS12615	COG2267	carboxylic ester hydrolase activity
H7F26_RS12625	COG1744	ABC transporter substrate-binding protein PnrA-like
H7F26_RS12640	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H7F26_RS12645	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H7F26_RS12650	COG5504	Zn-dependent protease
H7F26_RS12655	COG0444	Belongs to the ABC transporter superfamily
H7F26_RS12660	COG4608	Belongs to the ABC transporter superfamily
H7F26_RS12670	COG0601	transmembrane transport
H7F26_RS12675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7F26_RS12700	COG0180	Tryptophanyl-tRNA synthetase
H7F26_RS12710	COG0601	transmembrane transport
H7F26_RS12715	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7F26_RS12720	COG0444	Belongs to the ABC transporter superfamily
H7F26_RS12725	COG4608	Belongs to the ABC transporter superfamily
H7F26_RS12730	COG0456	acetyltransferase
H7F26_RS12735	COG1393	Belongs to the ArsC family
H7F26_RS12740	COG0861	Integral membrane protein TerC family
H7F26_RS12750	COG4862	establishment of competence for transformation
H7F26_RS12770	COG4565	transcriptional regulatory protein
H7F26_RS12775	COG3290	protein histidine kinase activity
H7F26_RS12780	COG4469	Competence protein
H7F26_RS12785	COG1164	Oligoendopeptidase f
H7F26_RS12790	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H7F26_RS12795	COG2346	COG2346, Truncated hemoglobins
H7F26_RS12800	COG0741	lytic transglycosylase activity
H7F26_RS12805	COG4116	CYTH
H7F26_RS12815	COG2357	RelA SpoT domain protein
H7F26_RS12820	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H7F26_RS12825	COG0564	pseudouridine synthase activity
H7F26_RS12830	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H7F26_RS12835	COG0569	domain protein
H7F26_RS12835	COG0475	glutathione-regulated potassium exporter activity
H7F26_RS12840	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H7F26_RS12845	COG0352	thiamine-phosphate diphosphorylase activity
H7F26_RS12855	COG2104	thiamine diphosphate biosynthetic process
H7F26_RS12860	COG2022	thiamine diphosphate biosynthetic process
H7F26_RS12865	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H7F26_RS12870	COG0351	phosphomethylpyrimidine kinase
H7F26_RS12875	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
H7F26_RS12930	COG0210	DNA helicase
H7F26_RS12940	COG0586	Pfam SNARE associated Golgi protein
H7F26_RS12945	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H7F26_RS12950	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H7F26_RS12955	COG2246	polysaccharide biosynthetic process
H7F26_RS12960	COG2153	protein acetylation
H7F26_RS12965	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
H7F26_RS12970	COG2382	esterase
H7F26_RS12985	COG0626	cystathionine gamma-synthase activity
H7F26_RS12990	COG0626	cystathionine gamma-synthase activity
H7F26_RS12995	COG5505	Protein of unknown function (DUF819)
H7F26_RS13010	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H7F26_RS13015	COG3507	Belongs to the glycosyl hydrolase 43 family
H7F26_RS13030	COG0110	maltose O-acetyltransferase activity
H7F26_RS13040	COG0583	DNA-binding transcription factor activity
H7F26_RS13045	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H7F26_RS13050	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H7F26_RS13060	COG0583	DNA-binding transcription factor activity
H7F26_RS13065	COG0697	spore germination
H7F26_RS13070	COG0346	lactoylglutathione lyase activity
H7F26_RS13080	COG3584	3D domain protein
H7F26_RS13080	COG1388	LysM domain
H7F26_RS13085	COG2814	Major facilitator Superfamily
H7F26_RS13090	COG1309	transcriptional regulator
H7F26_RS13110	COG5444	nuclease activity
H7F26_RS13115	COG4195	phage-related replication protein
H7F26_RS13120	COG2856	Zn peptidase
H7F26_RS13125	COG1396	sequence-specific DNA binding
H7F26_RS13140	COG1522	sequence-specific DNA binding
H7F26_RS13145	COG1484	DNA-dependent DNA replication
H7F26_RS13165	COG1595	DNA-templated transcription, initiation
H7F26_RS13170	COG3728	DNA packaging
H7F26_RS13170	COG5484	DNA packaging
H7F26_RS13175	COG1783	phage Terminase large subunit
H7F26_RS13180	COG5518	Phage portal protein
H7F26_RS13185	COG0338	D12 class N6 adenine-specific DNA methyltransferase
H7F26_RS13190	COG4653	Phage capsid family
H7F26_RS13240	COG3953	SLT domain
H7F26_RS13240	COG5412	phage tail tape measure protein
H7F26_RS13245	COG1652	LysM domain
H7F26_RS13250	COG4193	domain, Protein
H7F26_RS13260	COG3628	GPW Gp25 family protein
H7F26_RS13265	COG3299	homolog of phage Mu protein gp47
H7F26_RS13270	COG3778	Protein conserved in bacteria
H7F26_RS13305	COG1802	Transcriptional regulator
H7F26_RS13310	COG1063	alcohol dehydrogenase
H7F26_RS13315	COG1312	Catalyzes the dehydration of D-mannonate
H7F26_RS13320	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_RS13325	COG1063	alcohol dehydrogenase
H7F26_RS13330	COG2271	Major facilitator Superfamily
H7F26_RS13345	COG0306	phosphate transporter
H7F26_RS13350	COG1392	Phosphate transport regulator
H7F26_RS13355	COG0405	Gamma-glutamyltransferase
H7F26_RS13360	COG5578	integral membrane protein
H7F26_RS13365	COG2972	Histidine kinase
H7F26_RS13370	COG4753	response regulator
H7F26_RS13370	COG2207	Transcriptional regulator
H7F26_RS13375	COG1653	transport
H7F26_RS13380	COG1175	transmembrane transport
H7F26_RS13385	COG0395	ABC-type sugar transport system, permease component
H7F26_RS13390	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
H7F26_RS13395	COG2207	Transcriptional regulator
H7F26_RS13400	COG2755	lipolytic protein G-D-S-L family
H7F26_RS13410	COG5578	integral membrane protein
H7F26_RS13425	COG2755	lipolytic protein G-D-S-L family
H7F26_RS13430	COG3401	FG-GAP repeat protein
H7F26_RS13435	COG0667	Aldo Keto reductase
H7F26_RS13440	COG2755	lipolytic protein G-D-S-L family
H7F26_RS13445	COG1874	Beta-galactosidase
H7F26_RS13455	COG1653	transport
H7F26_RS13460	COG4209	transmembrane transport
H7F26_RS13465	COG0395	ABC-type sugar transport system, permease component
H7F26_RS13470	COG0531	amino acid
H7F26_RS13475	COG0346	lactoylglutathione lyase activity
H7F26_RS13485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7F26_RS13490	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H7F26_RS13495	COG2362	D-Aminopeptidase
H7F26_RS13500	COG0601	transmembrane transport
H7F26_RS13505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7F26_RS13510	COG0444	Belongs to the ABC transporter superfamily
H7F26_RS13515	COG4166	transmembrane transport
H7F26_RS13520	COG1619	proteins homologs of microcin C7 resistance protein MccF
H7F26_RS13525	COG4948	Mandelate Racemase Muconate Lactonizing
H7F26_RS13530	COG0791	NLP P60 protein
H7F26_RS13535	COG4608	Belongs to the ABC transporter superfamily
H7F26_RS13540	COG1834	amidinotransferase
H7F26_RS13545	COG1607	acyl-coa hydrolase
H7F26_RS13555	COG3866	Pectate lyase
H7F26_RS13575	COG2318	DinB family
H7F26_RS13580	COG2076	Multidrug Resistance protein
H7F26_RS13585	COG2076	Multidrug Resistance protein
H7F26_RS13590	COG0788	formyltetrahydrofolate deformylase activity
H7F26_RS13595	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
H7F26_RS13600	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
H7F26_RS13605	COG1764	response to oxidative stress
H7F26_RS13610	COG1846	Transcriptional regulator
H7F26_RS13615	COG1764	response to oxidative stress
H7F26_RS13625	COG0590	tRNA wobble adenosine to inosine editing
H7F26_RS13630	COG0406	alpha-ribazole phosphatase activity
H7F26_RS13645	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
H7F26_RS13650	COG1404	Belongs to the peptidase S8 family
H7F26_RS13660	COG2239	Acts as a magnesium transporter
H7F26_RS13670	COG0582	viral genome integration into host DNA
H7F26_RS13675	COG2856	Zn peptidase
H7F26_RS13690	COG3620	sequence-specific DNA binding
H7F26_RS13705	COG3646	Phage regulatory protein
H7F26_RS13705	COG3645	SOS response
H7F26_RS13755	COG1484	DNA-dependent DNA replication
H7F26_RS13795	COG3331	DNA recombination
H7F26_RS13810	COG0629	single-stranded DNA binding
H7F26_RS13875	COG3728	DNA packaging
H7F26_RS13875	COG5484	DNA packaging
H7F26_RS13880	COG1783	phage Terminase large subunit
H7F26_RS14015	COG5444	nuclease activity
H7F26_RS14030	COG0789	Transcriptional regulator
H7F26_RS14045	COG1846	Transcriptional regulator
H7F26_RS14050	COG1793	dna ligase
H7F26_RS14050	COG3285	dna ligase
H7F26_RS14055	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
H7F26_RS14060	COG5001	Diguanylate cyclase
H7F26_RS14060	COG3300	MHYT domain
H7F26_RS14065	COG0586	Pfam SNARE associated Golgi protein
H7F26_RS14070	COG0861	Integral membrane protein TerC family
H7F26_RS14075	COG1191	sigma factor activity
H7F26_RS14095	COG0501	Belongs to the peptidase M48B family
H7F26_RS14100	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H7F26_RS14105	COG0768	penicillin binding
H7F26_RS14120	COG3594	Acyltransferase
H7F26_RS14125	COG5002	protein histidine kinase activity
H7F26_RS14130	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H7F26_RS14135	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
H7F26_RS14140	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
H7F26_RS14145	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H7F26_RS14150	COG0436	Aminotransferase
H7F26_RS14155	COG1850	ribulose-bisphosphate carboxylase activity
H7F26_RS14160	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
H7F26_RS14160	COG0235	Class ii aldolase
H7F26_RS14165	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
H7F26_RS14170	COG0346	lactoylglutathione lyase activity
H7F26_RS14175	COG3339	Conserved Protein
H7F26_RS14185	COG3852	Histidine kinase
H7F26_RS14190	COG1846	Transcriptional regulator
H7F26_RS14195	COG1360	Flagellar Motor Protein
H7F26_RS14200	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
H7F26_RS14205	COG0542	response to heat
H7F26_RS14210	COG3949	Membrane
H7F26_RS14215	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H7F26_RS14220	COG0720	synthase
H7F26_RS14225	COG0602	queuosine metabolic process
H7F26_RS14230	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
H7F26_RS14240	COG3739	integral membrane protein
H7F26_RS14245	COG3655	Transcriptional regulator
H7F26_RS14280	COG4873	Protein conserved in bacteria
H7F26_RS14290	COG3773	Cell wall hydrolase
H7F26_RS14295	COG2244	polysaccharide biosynthetic process
H7F26_RS14300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F26_RS14305	COG2217	Heavy metal translocating P-type atpase
H7F26_RS14310	COG0006	proline dipeptidase activity
H7F26_RS14320	COG1609	Transcriptional regulator
H7F26_RS14325	COG3711	transcriptional antiterminator
H7F26_RS14330	COG2190	(PTS) system
H7F26_RS14330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F26_RS14330	COG1263	PTS System
H7F26_RS14335	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F26_RS14340	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H7F26_RS14350	COG1533	DNA photolyase activity
H7F26_RS14355	COG0456	acetyltransferase
H7F26_RS14360	COG0840	transmembrane signaling receptor activity
H7F26_RS14365	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_RS14370	COG2084	Dehydrogenase
H7F26_RS14375	COG2340	Cysteine-rich secretory protein family
H7F26_RS14380	COG0768	penicillin binding
H7F26_RS14385	COG4191	Histidine kinase
H7F26_RS14390	COG0436	Aminotransferase
H7F26_RS14400	COG1714	RDD family
H7F26_RS14410	COG0784	Response regulator, receiver
H7F26_RS14410	COG0835	chemotaxis
H7F26_RS14420	COG2814	Major facilitator Superfamily
H7F26_RS14425	COG1376	ErfK ybiS ycfS ynhG family protein
H7F26_RS14430	COG1408	metallophosphoesterase
H7F26_RS14435	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_RS14440	COG2200	EAL domain
H7F26_RS14450	COG4703	Protein of unknown function (DUF1797)
H7F26_RS14460	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
H7F26_RS14470	COG0517	IMP dehydrogenase activity
H7F26_RS14475	COG0583	DNA-binding transcription factor activity
H7F26_RS14480	COG0716	FMN binding
H7F26_RS14490	COG0716	FMN binding
H7F26_RS14495	COG2171	N-acyltransferase activity
H7F26_RS14500	COG1473	amidohydrolase
H7F26_RS14510	COG0450	alkyl hydroperoxide reductase
H7F26_RS14515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F26_RS14530	COG0746	molybdenum cofactor guanylyltransferase activity
H7F26_RS14535	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H7F26_RS14540	COG0303	'Molybdopterin
H7F26_RS14545	COG1763	Mo-molybdopterin cofactor biosynthetic process
H7F26_RS14550	COG0314	molybdopterin synthase activity
H7F26_RS14555	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
H7F26_RS14565	COG1132	(ABC) transporter
H7F26_RS14570	COG1132	(ABC) transporter
H7F26_RS14580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7F26_RS14585	COG1136	(ABC) transporter
H7F26_RS14590	COG0577	efflux transmembrane transporter activity
H7F26_RS14595	COG1349	DNA-binding transcription factor activity
H7F26_RS14600	COG1105	Belongs to the carbohydrate kinase PfkB family
H7F26_RS14605	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7F26_RS14605	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7F26_RS14605	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F26_RS14625	COG0488	(ABC) transporter
H7F26_RS14635	COG2309	aminopeptidase activity
H7F26_RS14645	COG1077	Cell shape determining protein MreB Mrl
H7F26_RS14650	COG2002	toxin-antitoxin pair type II binding
H7F26_RS14655	COG3852	Histidine kinase
H7F26_RS14660	COG0569	domain protein
H7F26_RS14665	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
H7F26_RS14670	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
H7F26_RS14675	COG5503	Protein of unknown function (DUF1447)
H7F26_RS14680	COG0561	phosphatase activity
H7F26_RS14690	COG0242	peptide deformylase activity
H7F26_RS14700	COG0497	DNA recombination
H7F26_RS14705	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H7F26_RS14710	COG0022	dehydrogenase e1 component
H7F26_RS14715	COG0508	dehydrogenase complex catalyzes the overall conversion of
H7F26_RS14720	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H7F26_RS14725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F26_RS14735	COG1982	Orn Lys Arg decarboxylase major
H7F26_RS14740	COG4476	Belongs to the UPF0223 family
H7F26_RS14745	COG4493	Belongs to the UPF0637 family
H7F26_RS14755	COG0483	inositol monophosphate 1-phosphatase activity
H7F26_RS14775	COG1595	DNA-templated transcription, initiation
H7F26_RS14790	COG1217	gtp-binding protein TYPA
H7F26_RS14800	COG1846	Transcriptional regulator
H7F26_RS14805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H7F26_RS14810	COG4896	Protein conserved in bacteria
H7F26_RS14820	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
H7F26_RS14825	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
H7F26_RS14830	COG2066	Belongs to the glutaminase family
H7F26_RS14835	COG4838	Belongs to the UPF0358 family
H7F26_RS14840	COG0772	Belongs to the SEDS family
H7F26_RS14845	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
H7F26_RS14850	COG1612	heme a metabolic process
H7F26_RS14855	COG0109	protoheme IX farnesyltransferase activity
H7F26_RS14860	COG2010	Cytochrome c
H7F26_RS14860	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H7F26_RS14865	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H7F26_RS14870	COG1845	cytochrome c oxidase, subunit III
H7F26_RS14875	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H7F26_RS14880	COG3336	cytochrome c oxidase
H7F26_RS14890	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
H7F26_RS14895	COG2340	Cysteine-rich secretory protein family
H7F26_RS14910	COG3679	Belongs to the UPF0342 family
H7F26_RS14915	COG4471	UPF0298 protein
H7F26_RS14920	COG0742	ribosomal rna small subunit methyltransferase
H7F26_RS14925	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
H7F26_RS14930	COG3314	Sporulation integral membrane protein YlbJ
H7F26_RS14935	COG3480	Lon protease (S16) C-terminal proteolytic domain
H7F26_RS14940	COG1323	Belongs to the UPF0348 family
H7F26_RS14945	COG1399	metal-binding, possibly nucleic acid-binding protein
H7F26_RS14950	COG0333	Belongs to the bacterial ribosomal protein bL32 family
H7F26_RS14960	COG0454	-acetyltransferase
H7F26_RS14965	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H7F26_RS14970	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
H7F26_RS14975	COG2001	Belongs to the MraZ family
H7F26_RS14980	COG0275	rRNA processing
H7F26_RS14985	COG4839	cell division protein FtsL
H7F26_RS14990	COG0768	penicillin binding
H7F26_RS14995	COG0768	penicillin binding
H7F26_RS15000	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H7F26_RS15005	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H7F26_RS15010	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
H7F26_RS15015	COG0772	Belongs to the SEDS family
H7F26_RS15020	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
H7F26_RS15025	COG0812	UDP-N-acetylmuramate dehydrogenase activity
H7F26_RS15030	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H7F26_RS15035	COG3879	Bacterial protein of unknown function (DUF881)
H7F26_RS15040	COG3879	Bacterial protein of unknown function (DUF881)
H7F26_RS15045	COG3856	small basic protein
H7F26_RS15050	COG0849	cell division
H7F26_RS15055	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H7F26_RS15060	COG1404	Belongs to the peptidase S8 family
H7F26_RS15060	COG4412	M6 family metalloprotease domain protein
H7F26_RS15065	COG1404	Belongs to the peptidase S8 family
H7F26_RS15065	COG4412	M6 family metalloprotease domain protein
H7F26_RS15075	COG1191	sigma factor activity
H7F26_RS15080	COG1191	sigma factor activity
H7F26_RS15085	COG1119	ATPase activity
H7F26_RS15090	COG0500	methyltransferase
H7F26_RS15095	COG1873	PFAM PRC-barrel domain
H7F26_RS15100	COG1496	oxidoreductase activity
H7F26_RS15105	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
H7F26_RS15110	COG1799	cell septum assembly
H7F26_RS15115	COG0762	integral membrane protein
H7F26_RS15120	COG2302	S4 RNA-binding domain
H7F26_RS15125	COG3599	regulation of cell shape
H7F26_RS15130	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H7F26_RS15135	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H7F26_RS15140	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
H7F26_RS15145	COG0564	pseudouridine synthase activity
H7F26_RS15150	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
H7F26_RS15155	COG2233	PERMEase
H7F26_RS15160	COG0540	Belongs to the ATCase OTCase family
H7F26_RS15165	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
H7F26_RS15170	COG0505	Belongs to the CarA family
H7F26_RS15175	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
H7F26_RS15180	COG0543	2 iron, 2 sulfur cluster binding
H7F26_RS15185	COG0167	dihydroorotate dehydrogenase activity
H7F26_RS15190	COG0284	orotidine-5'-phosphate decarboxylase activity
H7F26_RS15195	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
H7F26_RS15205	COG0175	sulfate reduction
H7F26_RS15210	COG0306	phosphate transporter
H7F26_RS15215	COG2046	Belongs to the sulfate adenylyltransferase family
H7F26_RS15220	COG0529	Catalyzes the synthesis of activated sulfate
H7F26_RS15225	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H7F26_RS15230	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
H7F26_RS15235	COG1648	precorrin-2 dehydrogenase activity
H7F26_RS15245	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H7F26_RS15250	COG1561	YicC-like family, N-terminal region
H7F26_RS15255	COG2052	Domain of unknown function (DUF370)
H7F26_RS15260	COG0194	GDP metabolic process
H7F26_RS15265	COG1758	RNA polymerase activity
H7F26_RS15270	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H7F26_RS15275	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H7F26_RS15280	COG0242	peptide deformylase activity
H7F26_RS15285	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
H7F26_RS15290	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
H7F26_RS15290	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H7F26_RS15295	COG0820	rRNA (adenine-C2-)-methyltransferase activity
H7F26_RS15300	COG0631	protein serine/threonine phosphatase activity
H7F26_RS15305	COG0515	serine threonine protein kinase
H7F26_RS15305	COG2815	serine threonine protein kinase
H7F26_RS15310	COG1162	GTPase activity
H7F26_RS15315	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H7F26_RS15320	COG1564	THIamine pyrophosphokinase
H7F26_RS15330	COG0227	Belongs to the bacterial ribosomal protein bL28 family
H7F26_RS15335	COG1302	Protein conserved in bacteria
H7F26_RS15340	COG1461	Dihydroxyacetone kinase
H7F26_RS15345	COG1760	l-serine dehydratase
H7F26_RS15350	COG1760	l-serine dehydratase
H7F26_RS15355	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H7F26_RS15360	COG1349	DNA-binding transcription factor activity
H7F26_RS15365	COG0416	fatty acid biosynthetic process
H7F26_RS15370	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H7F26_RS15375	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_RS15380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H7F26_RS15385	COG0571	ribonuclease III activity
H7F26_RS15390	COG1196	nuclear chromosome segregation
H7F26_RS15395	COG0552	protein localization to endoplasmic reticulum
H7F26_RS15400	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
H7F26_RS15405	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H7F26_RS15410	COG0228	four-way junction DNA binding
H7F26_RS15415	COG1837	Belongs to the UPF0109 family
H7F26_RS15425	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H7F26_RS15430	COG0336	Belongs to the RNA methyltransferase TrmD family
H7F26_RS15435	COG0335	large ribosomal subunit rRNA binding
H7F26_RS15440	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
H7F26_RS15445	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H7F26_RS15455	COG2257	FlhB HrpN YscU SpaS Family
H7F26_RS15460	COG0045	succinate-CoA ligase (ADP-forming) activity
H7F26_RS15465	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H7F26_RS15470	COG0758	DNA mediated transformation
H7F26_RS15475	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H7F26_RS15480	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
H7F26_RS15485	COG4974	Belongs to the 'phage' integrase family
H7F26_RS15490	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
H7F26_RS15495	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
H7F26_RS15500	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
H7F26_RS15505	COG1815	bacterial-type flagellum-dependent cell motility
H7F26_RS15510	COG1558	bacterial-type flagellum-dependent cell motility
H7F26_RS15515	COG1677	Flagellar hook-basal body complex protein FliE
H7F26_RS15520	COG1766	The M ring may be actively involved in energy transduction
H7F26_RS15525	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H7F26_RS15530	COG1317	bacterial-type flagellum organization
H7F26_RS15535	COG1157	protein secretion by the type III secretion system
H7F26_RS15540	COG2882	bacterial-type flagellum organization
H7F26_RS15550	COG3144	bacterial-type flagellum assembly
H7F26_RS15555	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
H7F26_RS15560	COG4786	Flagellar basal body rod
H7F26_RS15565	COG1582	Flagellar protein (FlbD)
H7F26_RS15570	COG1580	Controls the rotational direction of flagella during chemotaxis
H7F26_RS15575	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H7F26_RS15580	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H7F26_RS15580	COG1776	CheC inhibitor of MCP methylation
H7F26_RS15585	COG2201	protein-glutamate methylesterase activity
H7F26_RS15590	COG3190	flagellar
H7F26_RS15595	COG1338	Plays a role in the flagellum-specific transport system
H7F26_RS15600	COG1987	bacterial-type flagellum assembly
H7F26_RS15605	COG1684	flagellar biosynthetic protein fliR
H7F26_RS15610	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H7F26_RS15615	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H7F26_RS15620	COG1419	protein localization to endoplasmic reticulum
H7F26_RS15625	COG0455	bacterial-type flagellum organization
H7F26_RS15630	COG2201	protein-glutamate methylesterase activity
H7F26_RS15635	COG0643	Histidine kinase
H7F26_RS15635	COG2198	Histidine kinase
H7F26_RS15640	COG0835	chemotaxis
H7F26_RS15645	COG1776	CheC inhibitor of MCP methylation
H7F26_RS15650	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
H7F26_RS15655	COG1191	sigma factor activity
H7F26_RS15665	COG0052	Belongs to the universal ribosomal protein uS2 family
H7F26_RS15670	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
H7F26_RS15675	COG0528	UMP kinase activity
H7F26_RS15680	COG0233	cytoplasmic translational termination
H7F26_RS15685	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H7F26_RS15690	COG4589	Belongs to the CDS family
H7F26_RS15695	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
H7F26_RS15700	COG0750	zinc metalloprotease
H7F26_RS15705	COG0442	prolyl-tRNA aminoacylation
H7F26_RS15710	COG2176	DNA-directed DNA polymerase activity
H7F26_RS15735	COG0779	Required for maturation of 30S ribosomal subunits
H7F26_RS15740	COG0195	Participates in both transcription termination and antitermination
H7F26_RS15745	COG2740	Nucleic-acid-binding protein implicated in transcription termination
H7F26_RS15750	COG1358	cellular component organization or biogenesis
H7F26_RS15755	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
H7F26_RS15760	COG1550	Protein conserved in bacteria
H7F26_RS15765	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
H7F26_RS15770	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H7F26_RS15775	COG0196	riboflavin kinase activity
H7F26_RS15780	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
H7F26_RS15785	COG1185	polyribonucleotide nucleotidyltransferase activity
H7F26_RS15790	COG0726	polysaccharide deacetylase
H7F26_RS15795	COG0612	Peptidase, M16
H7F26_RS15800	COG1873	PFAM PRC-barrel domain
H7F26_RS15805	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H7F26_RS15810	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H7F26_RS15815	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H7F26_RS15820	COG0527	aspartate kinase activity
H7F26_RS15830	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
H7F26_RS15835	COG0740	serine-type endopeptidase activity
H7F26_RS15845	COG4980	gas vesicle protein
H7F26_RS15845	COG1674	ftsk spoiiie
H7F26_RS15850	COG2188	Transcriptional regulator
H7F26_RS15855	COG2814	Major facilitator Superfamily
H7F26_RS15860	COG0612	Peptidase, M16
H7F26_RS15865	COG0612	Peptidase, M16
H7F26_RS15870	COG0300	oxidoreductase activity
H7F26_RS15885	COG1426	Protein conserved in bacteria
H7F26_RS15890	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H7F26_RS15895	COG1058	Belongs to the CinA family
H7F26_RS15895	COG1546	Belongs to the CinA family
H7F26_RS15905	COG1418	mRNA catabolic process
H7F26_RS15910	COG1692	metallophosphoesterase
H7F26_RS15915	COG2359	stage V sporulation protein S
H7F26_RS15925	COG1063	alcohol dehydrogenase
H7F26_RS15930	COG0156	8-amino-7-oxononanoate synthase activity
H7F26_RS15935	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H7F26_RS15940	COG4550	Control of competence regulator ComK, YlbF/YmcA
H7F26_RS15950	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
H7F26_RS15955	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H7F26_RS15960	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H7F26_RS15965	COG5444	nuclease activity
H7F26_RS15980	COG0523	cobalamin synthesis protein
H7F26_RS15990	COG1247	-acetyltransferase
H7F26_RS16005	COG1231	oxidoreductase activity
H7F26_RS16010	COG3619	membrane
H7F26_RS16015	COG3263	regulation of cellular component size
H7F26_RS16035	COG0393	Putative heavy-metal-binding
H7F26_RS16040	COG0398	Pfam SNARE associated Golgi protein
H7F26_RS16045	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H7F26_RS16050	COG1819	glycosyl
H7F26_RS16055	COG0531	amino acid
H7F26_RS16060	COG5577	PFAM Coat F domain
H7F26_RS16070	COG1388	LysM domain
H7F26_RS16070	COG3858	chitin binding
H7F26_RS16075	COG1309	transcriptional regulator
H7F26_RS16080	COG3631	Ketosteroid isomerase-related protein
H7F26_RS16085	COG0702	epimerase
H7F26_RS16095	COG1764	response to oxidative stress
H7F26_RS16100	COG2076	Multidrug Resistance protein
H7F26_RS16105	COG2076	Multidrug Resistance protein
H7F26_RS16120	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
H7F26_RS16125	COG1923	regulation of RNA biosynthetic process
H7F26_RS16135	COG1780	Probably involved in ribonucleotide reductase function
H7F26_RS16140	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H7F26_RS16145	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H7F26_RS16150	COG4112	unkown
H7F26_RS16165	COG0735	belongs to the Fur family
H7F26_RS16170	COG1802	Transcriptional regulator
H7F26_RS16175	COG0697	spore germination
H7F26_RS16210	COG1309	transcriptional regulator
H7F26_RS16245	COG4282	regulation of fungal-type cell wall biogenesis
H7F26_RS16270	COG0464	growth
H7F26_RS16275	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H7F26_RS16280	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
H7F26_RS16285	COG0789	Transcriptional regulator
H7F26_RS16290	COG0174	glutamine synthetase
H7F26_RS16325	COG1073	alpha beta
H7F26_RS16370	COG1309	transcriptional regulator
H7F26_RS16375	COG2076	Multidrug Resistance protein
H7F26_RS16380	COG2076	Multidrug Resistance protein
H7F26_RS16405	COG3546	catalase activity
H7F26_RS16430	COG1846	Transcriptional regulator
H7F26_RS16435	COG0778	Nitroreductase
H7F26_RS16440	COG0346	lactoylglutathione lyase activity
H7F26_RS16445	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H7F26_RS16450	COG0655	NAD(P)H dehydrogenase (quinone) activity
H7F26_RS16475	COG3209	COG3209 Rhs family protein
H7F26_RS16480	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H7F26_RS16485	COG1388	LysM domain
H7F26_RS16490	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H7F26_RS16495	COG4224	UPF0291 protein
H7F26_RS16500	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H7F26_RS16510	COG3763	UPF0154 protein
H7F26_RS16520	COG0785	Cytochrome C biogenesis protein
H7F26_RS16525	COG2201	protein-glutamate methylesterase activity
H7F26_RS16530	COG4846	Membrane protein involved in cytochrome C biogenesis
H7F26_RS16540	COG0071	Belongs to the small heat shock protein (HSP20) family
H7F26_RS16555	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H7F26_RS16560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F26_RS16580	COG0824	Thioesterase
H7F26_RS16600	COG4841	protein insertion into membrane
H7F26_RS16605	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
H7F26_RS16610	COG1832	CoA-binding protein
H7F26_RS16615	COG0187	DNA topoisomerase II activity
H7F26_RS16620	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H7F26_RS16625	COG1609	Transcriptional regulator
H7F26_RS16640	COG2160	L-arabinose isomerase activity
H7F26_RS16660	COG1115	amino acid carrier protein
H7F26_RS16670	COG2181	nitrate reductase activity
H7F26_RS16675	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
H7F26_RS16680	COG1140	nitrate reductase beta subunit
H7F26_RS16685	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
H7F26_RS16700	COG0535	radical SAM domain protein
H7F26_RS16705	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H7F26_RS16715	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H7F26_RS16720	COG2223	nitrite transmembrane transporter activity
H7F26_RS16740	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
H7F26_RS16750	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
H7F26_RS16760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7F26_RS16775	COG3420	alginic acid biosynthetic process
H7F26_RS16780	COG1114	Component of the transport system for branched-chain amino acids
H7F26_RS16790	COG0789	Transcriptional regulator
H7F26_RS16815	COG1024	Enoyl-CoA hydratase
H7F26_RS16820	COG1012	belongs to the aldehyde dehydrogenase family
H7F26_RS16825	COG2084	Dehydrogenase
H7F26_RS16830	COG1960	acyl-CoA dehydrogenase activity
H7F26_RS16835	COG1482	cell wall glycoprotein biosynthetic process
H7F26_RS16840	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7F26_RS16840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F26_RS16840	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7F26_RS16860	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F26_RS16860	COG3711	transcriptional antiterminator
H7F26_RS16875	COG1725	Transcriptional regulator
H7F26_RS16880	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_RS16885	COG1312	Catalyzes the dehydration of D-mannonate
H7F26_RS16900	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
H7F26_RS16910	COG1609	Transcriptional regulator
H7F26_RS16915	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H7F26_RS16920	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H7F26_RS16925	COG0640	Transcriptional regulator
H7F26_RS16930	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
H7F26_RS16945	COG1649	PFAM Uncharacterised BCR, COG1649
H7F26_RS16950	COG2404	hydrolase activity, acting on ester bonds
H7F26_RS16955	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H7F26_RS16965	COG2027	D-alanyl-D-alanine carboxypeptidase
H7F26_RS16970	COG1252	NADH dehydrogenase
H7F26_RS16980	COG0166	Belongs to the GPI family
H7F26_RS16990	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H7F26_RS16995	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H7F26_RS17000	COG1024	Enoyl-CoA hydratase
H7F26_RS17005	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H7F26_RS17010	COG0511	ligase activity, forming carbon-carbon bonds
H7F26_RS17015	COG0439	Biotin carboxylase
H7F26_RS17020	COG0318	PFAM AMP-dependent synthetase and ligase
H7F26_RS17025	COG1960	acyl-CoA dehydrogenase activity
H7F26_RS17030	COG2249	NAD(P)H dehydrogenase (quinone) activity
H7F26_RS17035	COG1733	regulation of RNA biosynthetic process
H7F26_RS17040	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
H7F26_RS17045	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
H7F26_RS17055	COG2323	membrane
H7F26_RS17065	COG0306	phosphate transporter
H7F26_RS17070	COG0175	sulfate reduction
H7F26_RS17075	COG1809	phosphosulfolactate synthase activity
H7F26_RS17080	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H7F26_RS17085	COG4948	Mandelate Racemase Muconate Lactonizing
H7F26_RS17090	COG2814	Major facilitator Superfamily
H7F26_RS17095	COG0463	Glycosyl transferase, family 2
H7F26_RS17105	COG0493	'glutamate synthase
H7F26_RS17110	COG0070	glutamate synthase
H7F26_RS17110	COG0067	glutamate synthase
H7F26_RS17110	COG0069	glutamate synthase activity
H7F26_RS17115	COG0583	DNA-binding transcription factor activity
H7F26_RS17135	COG1846	Transcriptional regulator
H7F26_RS17145	COG1132	(ABC) transporter
H7F26_RS17155	COG0300	oxidoreductase activity
H7F26_RS17160	COG3848	Pyruvate phosphate dikinase
H7F26_RS17160	COG0574	Belongs to the PEP-utilizing enzyme family
H7F26_RS17165	COG0477	Major facilitator Superfamily
H7F26_RS17170	COG0243	molybdopterin cofactor binding
H7F26_RS17175	COG1846	Transcriptional regulator
H7F26_RS17185	COG0531	amino acid
H7F26_RS17195	COG0531	amino acid
H7F26_RS17200	COG0531	amino acid
H7F26_RS17205	COG0697	spore germination
H7F26_RS17210	COG0488	(ABC) transporter
H7F26_RS17215	COG0840	transmembrane signaling receptor activity
H7F26_RS17220	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7F26_RS17225	COG1404	Belongs to the peptidase S8 family
H7F26_RS17235	COG1309	transcriptional regulator
H7F26_RS17240	COG1846	Transcriptional regulator
H7F26_RS17270	COG1309	transcriptional regulator
H7F26_RS17275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7F26_RS17280	COG3708	Transcriptional regulator
H7F26_RS17290	COG2378	regulation of single-species biofilm formation
H7F26_RS17300	COG0640	Transcriptional regulator
H7F26_RS17305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7F26_RS17315	COG0531	amino acid
H7F26_RS17320	COG0741	lytic transglycosylase activity
H7F26_RS17325	COG1086	Polysaccharide biosynthesis protein
H7F26_RS17345	COG2322	membrane
H7F26_RS17360	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H7F26_RS17365	COG1388	LysM domain
H7F26_RS17365	COG3584	3D domain protein
H7F26_RS17370	COG0514	ATP-dependent DNA helicase (RecQ)
H7F26_RS17390	COG2315	Protein conserved in bacteria
H7F26_RS17405	COG0402	S-adenosylhomocysteine deaminase activity
H7F26_RS17420	COG2267	carboxylic ester hydrolase activity
H7F26_RS17435	COG1280	lysine exporter protein (LysE YggA)
H7F26_RS17440	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
H7F26_RS17450	COG0574	Belongs to the PEP-utilizing enzyme family
H7F26_RS17450	COG3848	Pyruvate phosphate dikinase
H7F26_RS17455	COG1309	transcriptional regulator
H7F26_RS17470	COG2318	DinB family
H7F26_RS17475	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H7F26_RS17480	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H7F26_RS17495	COG1012	belongs to the aldehyde dehydrogenase family
H7F26_RS17500	COG2814	Major facilitator Superfamily
H7F26_RS17515	COG1657	PFAM Prenyltransferase squalene oxidase
H7F26_RS17520	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H7F26_RS17530	COG0733	neurotransmitter:sodium symporter activity
H7F26_RS17535	COG0385	Bile acid
H7F26_RS17540	COG0508	dehydrogenase complex catalyzes the overall conversion of
H7F26_RS17545	COG0567	Dehydrogenase, E1 component
H7F26_RS17550	COG4548	von Willebrand factor, type A
H7F26_RS17555	COG0714	Associated with various cellular activities
H7F26_RS17560	COG2032	superoxide dismutase activity
H7F26_RS17565	COG1388	LysM domain
H7F26_RS17565	COG0791	NLP P60 protein
H7F26_RS17570	COG0534	Mate efflux family protein
H7F26_RS17575	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H7F26_RS17580	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H7F26_RS17590	COG2962	Rard protein
H7F26_RS17600	COG4305	rare lipoprotein A
H7F26_RS17610	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_RS17615	COG1733	regulation of RNA biosynthetic process
H7F26_RS17620	COG0778	Nitroreductase
H7F26_RS17625	COG0400	carboxylic ester hydrolase activity
H7F26_RS17635	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H7F26_RS17645	COG3409	Peptidoglycan-binding domain 1 protein
H7F26_RS17645	COG0793	Belongs to the peptidase S41A family
H7F26_RS17650	COG2226	methyltransferase
H7F26_RS17660	COG1876	peptidase activity
H7F26_RS17665	COG0813	purine-nucleoside phosphorylase activity
H7F26_RS17670	COG0701	Predicted permease
H7F26_RS17690	COG0671	phosphoesterase, PA-phosphatase related
H7F26_RS17705	COG4479	Belongs to the UPF0346 family
H7F26_RS17715	COG1509	lysine 2,3-aminomutase activity
H7F26_RS17720	COG0456	acetyltransferase
H7F26_RS17725	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H7F26_RS17730	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H7F26_RS17735	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H7F26_RS17740	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H7F26_RS17755	COG0456	acetyltransferase
H7F26_RS17760	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H7F26_RS17765	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H7F26_RS17770	COG1846	Transcriptional regulator
H7F26_RS17780	COG3706	GGDEF domain
H7F26_RS17785	COG0534	Mate efflux family protein
H7F26_RS17800	COG4698	Protein conserved in bacteria
H7F26_RS17805	COG2755	lipolytic protein G-D-S-L family
H7F26_RS17810	COG1999	signal sequence binding
H7F26_RS17825	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H7F26_RS17830	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
H7F26_RS17835	COG1272	protein, Hemolysin III
H7F26_RS17840	COG0204	Acyl-transferase
H7F26_RS17845	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H7F26_RS17850	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H7F26_RS17860	COG2521	methyltransferase
H7F26_RS17860	COG2136	Putative SAM-dependent methyltransferase
H7F26_RS17870	COG0129	dihydroxy-acid dehydratase activity
H7F26_RS17875	COG1413	lyase activity
H7F26_RS17880	COG1418	mRNA catabolic process
H7F26_RS17885	COG0386	Belongs to the glutathione peroxidase family
H7F26_RS17890	COG2759	Belongs to the formate--tetrahydrofolate ligase family
H7F26_RS17895	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
H7F26_RS17900	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
H7F26_RS17910	COG1278	Cold shock
H7F26_RS17930	COG0328	RNA-DNA hybrid ribonuclease activity
H7F26_RS17935	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
H7F26_RS17940	COG0328	RNA-DNA hybrid ribonuclease activity
H7F26_RS17950	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H7F26_RS17965	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
H7F26_RS17975	COG1755	Isoprenylcysteine carboxyl methyltransferase
H7F26_RS17980	COG3424	synthase
H7F26_RS17985	COG0456	acetyltransferase
H7F26_RS17990	COG2233	PERMEase
H7F26_RS17995	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
H7F26_RS18000	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
H7F26_RS18005	COG1199	ATP-dependent helicase activity
H7F26_RS18020	COG0116	Belongs to the methyltransferase superfamily
H7F26_RS18030	COG3599	regulation of cell shape
H7F26_RS18035	COG4474	Belongs to the UPF0398 family
H7F26_RS18045	COG3359	exonuclease
H7F26_RS18050	COG1205	dead DEAH box helicase
H7F26_RS18050	COG1111	helicase
H7F26_RS18055	COG2190	(PTS) system
H7F26_RS18060	COG0071	Belongs to the small heat shock protein (HSP20) family
H7F26_RS18100	COG3331	DNA recombination
H7F26_RS18105	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H7F26_RS18105	COG4499	WXG100 protein secretion system (Wss), protein YukC
H7F26_RS18115	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H7F26_RS18120	COG3935	DnaD domain protein
H7F26_RS18125	COG0017	Asparaginyl-tRNA synthetase
H7F26_RS18130	COG0436	Aminotransferase
H7F26_RS18135	COG5353	protein conserved in bacteria
H7F26_RS18145	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H7F26_RS18145	COG1199	ATP-dependent helicase activity
H7F26_RS18150	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
H7F26_RS18155	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
H7F26_RS18160	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
H7F26_RS18170	COG0617	tRNA 3'-terminal CCA addition
H7F26_RS18175	COG0438	transferase activity, transferring glycosyl groups
H7F26_RS18180	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H7F26_RS18185	COG1803	Methylglyoxal synthase
H7F26_RS18190	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
H7F26_RS18195	COG1694	Mazg nucleotide pyrophosphohydrolase
H7F26_RS18200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H7F26_RS18210	COG4347	Protein of unknown function (DUF1405)
H7F26_RS18220	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
H7F26_RS18220	COG2010	Cytochrome c
H7F26_RS18225	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
H7F26_RS18230	COG0723	plastoquinol--plastocyanin reductase activity
H7F26_RS18240	COG5582	Belongs to the UPF0302 family
H7F26_RS18245	COG0457	Tetratricopeptide repeat
H7F26_RS18250	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H7F26_RS18255	COG0287	Prephenate dehydrogenase
H7F26_RS18260	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H7F26_RS18265	COG0159	tryptophan synthase activity
H7F26_RS18270	COG0133	tryptophan synthase activity
H7F26_RS18275	COG0135	phosphoribosylanthranilate isomerase activity
H7F26_RS18280	COG0134	indole-3-glycerol-phosphate synthase activity
H7F26_RS18285	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H7F26_RS18290	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H7F26_RS18295	COG4401	Chorismate mutase type I
H7F26_RS18300	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
H7F26_RS18305	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
H7F26_RS18310	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
H7F26_RS18315	COG0105	UTP biosynthetic process
H7F26_RS18320	COG0142	geranyltranstransferase activity
H7F26_RS18325	COG2226	methyltransferase
H7F26_RS18330	COG0142	geranyltranstransferase activity
H7F26_RS18345	COG0776	regulation of translation
H7F26_RS18350	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
H7F26_RS18365	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
H7F26_RS18370	COG1160	GTP binding
H7F26_RS18395	COG1304	FMN binding
H7F26_RS18400	COG0539	negative regulation of cytoplasmic translation
H7F26_RS18405	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
H7F26_RS18415	COG2959	enzyme of heme biosynthesis
H7F26_RS18420	COG3773	Cell wall hydrolase
H7F26_RS18420	COG3409	Peptidoglycan-binding domain 1 protein
H7F26_RS18425	COG2339	peptidase activity
H7F26_RS18435	COG0492	ferredoxin-NADP+ reductase activity
H7F26_RS18440	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H7F26_RS18445	COG4862	establishment of competence for transformation
H7F26_RS18450	COG1408	metallophosphoesterase
H7F26_RS18460	COG1388	LysM domain
H7F26_RS18465	COG1266	CAAX protease self-immunity
H7F26_RS18470	COG0514	ATP-dependent DNA helicase (RecQ)
H7F26_RS18475	COG4955	Helix-turn-helix domain
H7F26_RS18480	COG1141	Ferredoxin
H7F26_RS18485	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
H7F26_RS18490	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H7F26_RS18495	COG0739	heme binding
H7F26_RS18505	COG1595	DNA-templated transcription, initiation
H7F26_RS18510	COG1316	TRANSCRIPTIONal
H7F26_RS18525	COG5002	protein histidine kinase activity
H7F26_RS18530	COG0745	RESPONSE REGULATOR receiver
H7F26_RS18535	COG5002	protein histidine kinase activity
H7F26_RS18540	COG0745	RESPONSE REGULATOR receiver
H7F26_RS18545	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H7F26_RS18550	COG1333	cytochrome c biogenesis protein
H7F26_RS18555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F26_RS18560	COG1187	pseudouridine synthase activity
H7F26_RS18565	COG0700	Nucleoside recognition
H7F26_RS18570	COG2715	membrane protein required for spore maturation
H7F26_RS18575	COG1686	Belongs to the peptidase S11 family
H7F26_RS18585	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H7F26_RS18590	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
H7F26_RS18600	COG1547	Domain of unknown function (DUF309)
H7F26_RS18605	COG0456	acetyltransferase
H7F26_RS18610	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
H7F26_RS18615	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H7F26_RS18615	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H7F26_RS18620	COG0307	riboflavin synthase, alpha
H7F26_RS18625	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H7F26_RS18625	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H7F26_RS18650	COG0457	Tetratricopeptide repeat
H7F26_RS18655	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H7F26_RS18660	COG4086	secreted protein
H7F26_RS18665	COG4195	phage-related replication protein
H7F26_RS18670	COG0019	diaminopimelate decarboxylase activity
H7F26_RS18680	COG0697	spore germination
H7F26_RS18695	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H7F26_RS18730	COG1686	Belongs to the peptidase S11 family
H7F26_RS18735	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
H7F26_RS18740	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
H7F26_RS18745	COG4974	Belongs to the 'phage' integrase family
H7F26_RS18755	COG0735	belongs to the Fur family
H7F26_RS18760	COG1300	Membrane
H7F26_RS18765	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7F26_RS18785	COG2153	protein acetylation
H7F26_RS18790	COG1379	DNA repair
H7F26_RS18795	COG0494	nUDIX hydrolase
H7F26_RS18805	COG1309	transcriptional regulator
H7F26_RS18815	COG0667	Aldo Keto reductase
H7F26_RS18825	COG1073	alpha beta
H7F26_RS18835	COG4918	Iron-sulphur cluster biosynthesis
H7F26_RS18850	COG2329	Antibiotic biosynthesis monooxygenase
H7F26_RS18855	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
H7F26_RS18865	COG0747	negative chemotaxis
H7F26_RS18870	COG0601	transmembrane transport
H7F26_RS18880	COG0444	Belongs to the ABC transporter superfamily
H7F26_RS18890	COG0534	Mate efflux family protein
H7F26_RS18905	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H7F26_RS18915	COG2211	Major facilitator Superfamily
H7F26_RS18920	COG0346	lactoylglutathione lyase activity
H7F26_RS18925	COG1072	(Pantothenic acid kinase))
H7F26_RS18935	COG1131	(ABC) transporter
H7F26_RS18955	COG4195	phage-related replication protein
H7F26_RS18960	COG0300	oxidoreductase activity
H7F26_RS18965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7F26_RS18970	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H7F26_RS18975	COG4187	Peptidase family M20/M25/M40
H7F26_RS18980	COG1902	pentaerythritol trinitrate reductase activity
H7F26_RS18985	COG0596	Alpha beta hydrolase
H7F26_RS18990	COG0267	Belongs to the bacterial ribosomal protein bL33 family
H7F26_RS18995	COG1234	tRNA 3'-trailer cleavage
H7F26_RS19000	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
H7F26_RS19015	COG2358	TRAP transporter, solute receptor (TAXI family
H7F26_RS19020	COG2188	Transcriptional regulator
H7F26_RS19025	COG2723	6-phospho-beta-galactosidase activity
H7F26_RS19030	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7F26_RS19035	COG1447	Phosphotransferase system cellobiose-specific component IIA
H7F26_RS19040	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7F26_RS19045	COG1785	Belongs to the alkaline phosphatase family
H7F26_RS19050	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_RS19055	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
H7F26_RS19060	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H7F26_RS19070	COG0706	membrane insertase activity
H7F26_RS19075	COG2195	Cleaves the N-terminal amino acid of tripeptides
H7F26_RS19080	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H7F26_RS19090	COG4129	membrane
H7F26_RS19095	COG1126	abc transporter atp-binding protein
H7F26_RS19100	COG0765	amino acid transport
H7F26_RS19105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F26_RS19120	COG1597	lipid kinase activity
H7F26_RS19125	COG0508	dehydrogenase complex catalyzes the overall conversion of
H7F26_RS19130	COG0022	dehydrogenase e1 component
H7F26_RS19135	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H7F26_RS19140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H7F26_RS19145	COG3426	butyrate kinase activity
H7F26_RS19155	COG0280	phosphate acetyltransferase
H7F26_RS19160	COG3829	transcription factor binding
H7F26_RS19160	COG3290	protein histidine kinase activity
H7F26_RS19170	COG0584	glycerophosphoryl diester phosphodiesterase
H7F26_RS19175	COG0860	N-Acetylmuramoyl-L-alanine amidase
H7F26_RS19190	COG1045	serine acetyltransferase
H7F26_RS19200	COG0745	RESPONSE REGULATOR receiver
H7F26_RS19205	COG0750	zinc metalloprotease
H7F26_RS19210	COG0497	DNA recombination
H7F26_RS19215	COG1438	arginine binding
H7F26_RS19220	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
H7F26_RS19225	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
H7F26_RS19230	COG0142	geranyltranstransferase activity
H7F26_RS19235	COG1722	exodeoxyribonuclease VII activity
H7F26_RS19240	COG1570	exodeoxyribonuclease VII activity
H7F26_RS19245	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
H7F26_RS19250	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H7F26_RS19255	COG1302	Protein conserved in bacteria
H7F26_RS19260	COG0439	Biotin carboxylase
H7F26_RS19265	COG0511	ligase activity, forming carbon-carbon bonds
H7F26_RS19305	COG3854	ATPases associated with a variety of cellular activities
H7F26_RS19315	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
H7F26_RS19320	COG0006	proline dipeptidase activity
H7F26_RS19325	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
H7F26_RS19335	COG3872	metal-dependent enzyme
H7F26_RS19345	COG1752	Esterase of the alpha-beta hydrolase superfamily
H7F26_RS19350	COG1321	iron dependent repressor
H7F26_RS19355	COG0095	Lipoate-protein ligase
H7F26_RS19360	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H7F26_RS19365	COG2113	Glycine betaine
H7F26_RS19370	COG4176	ABC-type proline glycine betaine transport system permease component
H7F26_RS19375	COG0517	IMP dehydrogenase activity
H7F26_RS19375	COG4175	Glycine betaine
H7F26_RS19380	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
H7F26_RS19385	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
H7F26_RS19390	COG0404	The glycine cleavage system catalyzes the degradation of glycine
H7F26_RS19395	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
H7F26_RS19420	COG0681	Belongs to the peptidase S26 family
H7F26_RS19445	COG4940	Competence protein ComGF
H7F26_RS19455	COG4970	Tfp pilus assembly protein FimT
H7F26_RS19460	COG4537	Required for transformation and DNA binding
H7F26_RS19465	COG1459	type II secretion system
H7F26_RS19470	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H7F26_RS19475	COG1366	Belongs to the anti-sigma-factor antagonist family
H7F26_RS19485	COG1393	Belongs to the ArsC family
H7F26_RS19495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7F26_RS19505	COG0011	TIGRFAM Protein of
H7F26_RS19515	COG2866	Carboxypeptidase
H7F26_RS19520	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H7F26_RS19530	COG1368	sulfuric ester hydrolase activity
H7F26_RS19535	COG1940	carbohydrate kinase activity
H7F26_RS19540	COG4483	Protein conserved in bacteria
H7F26_RS19545	COG0697	spore germination
H7F26_RS19550	COG0705	Rhomboid family
H7F26_RS19550	COG0457	Tetratricopeptide repeat
H7F26_RS19560	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H7F26_RS19565	COG0267	Belongs to the bacterial ribosomal protein bL33 family
H7F26_RS19570	COG0438	transferase activity, transferring glycosyl groups
H7F26_RS19585	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H7F26_RS19590	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H7F26_RS19595	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H7F26_RS19600	COG0581	inorganic phosphate transmembrane transporter activity
H7F26_RS19605	COG0573	inorganic phosphate transmembrane transporter activity
H7F26_RS19610	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H7F26_RS19615	COG0768	penicillin binding
H7F26_RS19620	COG0477	Major facilitator Superfamily
H7F26_RS19625	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H7F26_RS19630	COG2839	Protein conserved in bacteria
H7F26_RS19635	COG5521	maltodextrose utilization protein MalA
H7F26_RS19640	COG1388	LysM domain
H7F26_RS19645	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
H7F26_RS19650	COG4709	membrane
H7F26_RS19655	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
H7F26_RS19660	COG0735	belongs to the Fur family
H7F26_RS19665	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H7F26_RS19670	COG1121	(ABC) transporter
H7F26_RS19675	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H7F26_RS19685	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
H7F26_RS19690	COG0513	Belongs to the DEAD box helicase family
H7F26_RS19700	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
H7F26_RS19705	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H7F26_RS19710	COG2384	SAM-dependent methyltransferase
H7F26_RS19755	COG5444	nuclease activity
H7F26_RS19770	COG2010	Cytochrome c
H7F26_RS19775	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H7F26_RS19780	COG0358	DNA primase activity
H7F26_RS19785	COG1671	Belongs to the UPF0178 family
H7F26_RS19790	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
H7F26_RS19795	COG0517	IMP dehydrogenase activity
H7F26_RS19800	COG0751	glycine-tRNA ligase activity
H7F26_RS19805	COG0752	glycyl-tRNA synthetase alpha subunit
H7F26_RS19810	COG1381	Involved in DNA repair and RecF pathway recombination
H7F26_RS19820	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H7F26_RS19825	COG0295	cytidine deaminase activity
H7F26_RS19830	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
H7F26_RS19835	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
H7F26_RS19840	COG1480	7TM receptor with intracellular HD hydrolase
H7F26_RS19845	COG1702	phosphate starvation-inducible protein PhoH
H7F26_RS19850	COG0561	phosphatase activity
H7F26_RS19865	COG4864	UPF0365 protein
H7F26_RS19870	COG1030	water channel activity
H7F26_RS19875	COG1610	YqeY-like protein
H7F26_RS19880	COG0828	Belongs to the bacterial ribosomal protein bS21 family
H7F26_RS19885	COG1283	sodium-dependent phosphate transmembrane transporter activity
H7F26_RS19890	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
H7F26_RS19895	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H7F26_RS19900	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H7F26_RS19905	COG2264	protein methyltransferase activity
H7F26_RS19910	COG0484	heat shock protein binding
H7F26_RS19915	COG0443	Heat shock 70 kDa protein
H7F26_RS19920	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
H7F26_RS19925	COG1420	regulation of RNA biosynthetic process
H7F26_RS19930	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H7F26_RS19935	COG0481	GTPase activity
H7F26_RS19945	COG0860	N-Acetylmuramoyl-L-alanine amidase
H7F26_RS19950	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
H7F26_RS19955	COG0268	Binds directly to 16S ribosomal RNA
H7F26_RS19960	COG1466	dna polymerase III delta subunit
H7F26_RS19970	COG2333	competence protein COMEC
H7F26_RS19970	COG0658	competence protein
H7F26_RS19975	COG2131	deaminase
H7F26_RS19980	COG1596	polysaccharide export
H7F26_RS19980	COG1555	photosystem II stabilization
H7F26_RS19985	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H7F26_RS19990	COG2226	methyltransferase
H7F26_RS19995	COG0799	negative regulation of ribosome biogenesis
H7F26_RS20000	COG1713	HD superfamily hydrolase involved in NAD metabolism
H7F26_RS20005	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
H7F26_RS20010	COG1534	Rna-binding protein
H7F26_RS20015	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H7F26_RS20020	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
H7F26_RS20025	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
H7F26_RS20040	COG2755	lipolytic protein G-D-S-L family
H7F26_RS20045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7F26_RS20050	COG5609	conserved protein (DUF2294)
H7F26_RS20055	COG3383	formate dehydrogenase (NAD+) activity
H7F26_RS20060	COG2427	Protein of unknown function (DUF1641)
H7F26_RS20090	COG0860	N-Acetylmuramoyl-L-alanine amidase
H7F26_RS20135	COG1136	(ABC) transporter
H7F26_RS20140	COG0577	efflux transmembrane transporter activity
H7F26_RS20220	COG2197	response regulator
H7F26_RS20225	COG4585	Histidine kinase
H7F26_RS20230	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F26_RS20235	COG0730	response to heat
H7F26_RS20240	COG0425	Belongs to the sulfur carrier protein TusA family
H7F26_RS20250	COG0425	Belongs to the sulfur carrier protein TusA family
H7F26_RS20250	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H7F26_RS20255	COG2210	Belongs to the sulfur carrier protein TusA family
H7F26_RS20260	COG1937	Protein conserved in bacteria
H7F26_RS20305	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
H7F26_RS20310	COG0113	porphobilinogen synthase activity
H7F26_RS20315	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H7F26_RS20320	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
H7F26_RS20325	COG1733	regulation of RNA biosynthetic process
H7F26_RS20330	COG3239	Fatty acid desaturase
H7F26_RS20335	COG4585	Histidine kinase
H7F26_RS20340	COG2197	response regulator
H7F26_RS20345	COG0492	ferredoxin-NADP+ reductase activity
H7F26_RS20350	COG0747	negative chemotaxis
H7F26_RS20355	COG0601	transmembrane transport
H7F26_RS20360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7F26_RS20365	COG0444	Belongs to the ABC transporter superfamily
H7F26_RS20370	COG4608	Belongs to the ABC transporter superfamily
H7F26_RS20390	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_RS20405	COG2124	cytochrome p450
H7F26_RS20410	COG0730	response to heat
H7F26_RS20420	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_RS20425	COG1621	beta-fructofuranosidase activity
H7F26_RS20430	COG3716	PTS system mannose fructose sorbose family IID component
H7F26_RS20435	COG3715	PTS system
H7F26_RS20440	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F26_RS20445	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F26_RS20450	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
H7F26_RS20450	COG3933	PFAM sigma-54 factor interaction domain-containing protein
H7F26_RS20475	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H7F26_RS20480	COG0656	L-ascorbic acid biosynthetic process
H7F26_RS20485	COG2814	Major facilitator Superfamily
H7F26_RS20490	COG1733	regulation of RNA biosynthetic process
H7F26_RS20495	COG3340	Belongs to the peptidase S51 family
H7F26_RS20500	COG1587	Uroporphyrinogen-III synthase
H7F26_RS20510	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H7F26_RS20515	COG0583	DNA-binding transcription factor activity
H7F26_RS20520	COG2814	Major facilitator Superfamily
H7F26_RS20530	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H7F26_RS20530	COG2124	cytochrome p450
H7F26_RS20535	COG1309	transcriptional regulator
H7F26_RS20540	COG1404	Belongs to the peptidase S8 family
H7F26_RS20545	COG2226	methyltransferase
H7F26_RS20570	COG0626	cystathionine gamma-synthase activity
H7F26_RS20575	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H7F26_RS20580	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H7F26_RS20585	COG2226	methyltransferase
H7F26_RS20600	COG0768	penicillin binding
H7F26_RS20605	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H7F26_RS20610	COG0572	uridine kinase
H7F26_RS20615	COG0826	peptidase U32
H7F26_RS20620	COG0826	peptidase U32
H7F26_RS20625	COG4122	O-methyltransferase activity
H7F26_RS20630	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H7F26_RS20635	COG3906	Belongs to the UPF0473 family
H7F26_RS20640	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H7F26_RS20645	COG4472	Bacterial protein of unknown function (DUF965)
H7F26_RS20650	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
H7F26_RS20655	COG0628	permease
H7F26_RS20670	COG3881	PFAM PRC-barrel domain
H7F26_RS20675	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H7F26_RS20680	COG0457	Tetratricopeptide repeat
H7F26_RS20685	COG0482	sulfurtransferase activity
H7F26_RS20690	COG1104	cysteine desulfurase activity
H7F26_RS20695	COG1959	2 iron, 2 sulfur cluster binding
H7F26_RS20700	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H7F26_RS20705	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H7F26_RS20715	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
H7F26_RS20720	COG0124	histidyl-tRNA synthetase
H7F26_RS20730	COG3103	Sh3 type 3 domain protein
H7F26_RS20730	COG0860	N-Acetylmuramoyl-L-alanine amidase
H7F26_RS20730	COG4991	sh3 domain protein
H7F26_RS20735	COG1490	D-aminoacyl-tRNA deacylase activity
H7F26_RS20740	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H7F26_RS20745	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
H7F26_RS20750	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
H7F26_RS20750	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H7F26_RS20755	COG5416	Lipopolysaccharide assembly protein A domain
H7F26_RS20760	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H7F26_RS20760	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H7F26_RS20770	COG2244	polysaccharide biosynthetic process
H7F26_RS20775	COG2323	membrane
H7F26_RS20785	COG1862	Preprotein translocase
H7F26_RS20790	COG0343	queuine tRNA-ribosyltransferase activity
H7F26_RS20795	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
H7F26_RS20805	COG2255	four-way junction helicase activity
H7F26_RS20810	COG0632	four-way junction helicase activity
H7F26_RS20820	COG2112	serine threonine protein kinase
H7F26_RS20830	COG2318	DinB family
H7F26_RS20835	COG4195	phage-related replication protein
H7F26_RS20850	COG0217	transcriptional regulatory protein
H7F26_RS20860	COG1388	LysM domain
H7F26_RS20865	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
H7F26_RS20870	COG0157	Belongs to the NadC ModD family
H7F26_RS20875	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
H7F26_RS20880	COG1104	cysteine desulfurase activity
H7F26_RS20885	COG1827	regulation of RNA biosynthetic process
H7F26_RS20890	COG0077	Prephenate dehydratase
H7F26_RS20895	COG4492	Belongs to the UPF0735 family
H7F26_RS20900	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
H7F26_RS20905	COG3290	protein histidine kinase activity
H7F26_RS20910	COG0211	Belongs to the bacterial ribosomal protein bL27 family
H7F26_RS20915	COG2868	ribosomal protein
H7F26_RS20920	COG0261	This protein binds to 23S rRNA in the presence of protein L20
H7F26_RS20925	COG1994	Peptidase M50
H7F26_RS20930	COG0739	heme binding
H7F26_RS20935	COG3832	glyoxalase III activity
H7F26_RS20940	COG0640	Transcriptional regulator
H7F26_RS20945	COG2894	cell division
H7F26_RS20950	COG0850	regulation of cytokinetic process
H7F26_RS20955	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H7F26_RS20965	COG1077	Cell shape determining protein MreB Mrl
H7F26_RS20970	COG2003	Belongs to the UPF0758 family
H7F26_RS20975	COG0424	maF-like protein
H7F26_RS20985	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
H7F26_RS20990	COG0285	dihydrofolate synthase activity
H7F26_RS20995	COG0525	valine-tRNA ligase activity
H7F26_RS21005	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H7F26_RS21010	COG1388	LysM domain
H7F26_RS21015	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
H7F26_RS21020	COG0113	porphobilinogen synthase activity
H7F26_RS21025	COG1587	Uroporphyrinogen-III synthase
H7F26_RS21030	COG0181	hydroxymethylbilane synthase activity
H7F26_RS21035	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H7F26_RS21040	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
H7F26_RS21050	COG0218	Necessary for normal cell division and for the maintenance of normal septation
H7F26_RS21055	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
H7F26_RS21060	COG0470	DNA polymerase III
H7F26_RS21060	COG1067	ATP-dependent peptidase activity
H7F26_RS21065	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
H7F26_RS21070	COG0544	peptidyl-prolyl cis-trans isomerase activity
H7F26_RS21075	COG1477	protein flavinylation
H7F26_RS21075	COG0457	Tetratricopeptide repeat
H7F26_RS21080	COG0066	3-isopropylmalate dehydratase activity
H7F26_RS21085	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
H7F26_RS21090	COG0473	3-isopropylmalate dehydrogenase activity
H7F26_RS21095	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H7F26_RS21100	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
H7F26_RS21105	COG0440	acetolactate synthase activity
H7F26_RS21110	COG0028	Belongs to the TPP enzyme family
H7F26_RS21115	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H7F26_RS21125	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H7F26_RS21145	COG1783	phage Terminase large subunit
H7F26_RS21180	COG5444	nuclease activity
H7F26_RS21185	COG0457	Tetratricopeptide repeat
H7F26_RS21210	COG0622	Phosphoesterase
H7F26_RS21215	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
H7F26_RS21220	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
H7F26_RS21225	COG5401	PFAM Sporulation and spore germination
H7F26_RS21230	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H7F26_RS21235	COG1846	Transcriptional regulator
H7F26_RS21240	COG2197	response regulator
H7F26_RS21245	COG4221	oxidoreductase activity
H7F26_RS21250	COG0824	Thioesterase
H7F26_RS21255	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H7F26_RS21260	COG1053	succinate dehydrogenase
H7F26_RS21265	COG2009	succinate dehydrogenase
H7F26_RS21270	COG1719	4-vinyl reductase, 4VR
H7F26_RS21275	COG0527	aspartate kinase activity
H7F26_RS21280	COG0322	excinuclease ABC activity
H7F26_RS21285	COG3118	belongs to the thioredoxin family
H7F26_RS21290	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
H7F26_RS21295	COG2086	electron transfer activity
H7F26_RS21300	COG1024	Enoyl-CoA hydratase
H7F26_RS21305	COG1309	transcriptional regulator
H7F26_RS21310	COG0318	PFAM AMP-dependent synthetase and ligase
H7F26_RS21315	COG3766	membrane
H7F26_RS21320	COG1193	negative regulation of DNA recombination
H7F26_RS21325	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
H7F26_RS21325	COG1796	DNA polymerase
H7F26_RS21330	COG1286	toxin biosynthetic process
H7F26_RS21335	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
H7F26_RS21340	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H7F26_RS21360	COG1137	ATPase activity
H7F26_RS21375	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7F26_RS21375	COG0072	phenylalanine-tRNA ligase activity
H7F26_RS21380	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
H7F26_RS21385	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H7F26_RS21395	COG1966	Carbon starvation protein
H7F26_RS21410	COG0395	ABC-type sugar transport system, permease component
H7F26_RS21415	COG1175	transmembrane transport
H7F26_RS21420	COG1653	transport
H7F26_RS21425	COG0371	Dehydrogenase
H7F26_RS21430	COG0235	Class ii aldolase
H7F26_RS21435	COG1069	ribulokinase activity
H7F26_RS21440	COG2160	L-arabinose isomerase activity
H7F26_RS21445	COG3507	Belongs to the glycosyl hydrolase 43 family
H7F26_RS21450	COG1363	Peptidase, m42
H7F26_RS21460	COG3326	Membrane
H7F26_RS21465	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
H7F26_RS21470	COG0291	Belongs to the bacterial ribosomal protein bL35 family
H7F26_RS21475	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
H7F26_RS21480	COG1346	cytolysis
H7F26_RS21490	COG3540	Alkaline phosphatase
H7F26_RS21495	COG3279	Response regulator of the LytR AlgR family
H7F26_RS21500	COG3275	phosphorelay sensor kinase activity
H7F26_RS21510	COG1011	Hydrolase
H7F26_RS21515	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
H7F26_RS21525	COG0398	Pfam SNARE associated Golgi protein
H7F26_RS21530	COG1484	DNA-dependent DNA replication
H7F26_RS21535	COG3611	Membrane attachment protein
H7F26_RS21540	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
H7F26_RS21550	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
H7F26_RS21555	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H7F26_RS21560	COG3866	Pectate lyase
H7F26_RS21565	COG0237	dephospho-CoA kinase activity
H7F26_RS21570	COG1971	Probably functions as a manganese efflux pump
H7F26_RS21575	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
H7F26_RS21580	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H7F26_RS21580	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H7F26_RS21585	COG5002	protein histidine kinase activity
H7F26_RS21590	COG0745	RESPONSE REGULATOR receiver
H7F26_RS21595	COG0039	L-malate dehydrogenase activity
H7F26_RS21600	COG0538	isocitrate dehydrogenase activity
H7F26_RS21605	COG0372	Belongs to the citrate synthase family
H7F26_RS21610	COG2707	UPF0756 membrane protein
H7F26_RS21615	COG0628	permease
H7F26_RS21620	COG3030	protein affecting phage T7 exclusion by the F plasmid
H7F26_RS21630	COG0205	6-phosphofructokinase activity
H7F26_RS21635	COG0825	malonyl-CoA metabolic process
H7F26_RS21640	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
H7F26_RS21645	COG0281	malic enzyme
H7F26_RS21650	COG0587	DNA-directed DNA polymerase activity
H7F26_RS21670	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
H7F26_RS21680	COG4109	DRTGG domain
H7F26_RS21685	COG1695	Transcriptional regulator
H7F26_RS21690	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
H7F26_RS21695	COG1028	Short-chain dehydrogenase reductase Sdr
H7F26_RS21705	COG0165	Argininosuccinate lyase
H7F26_RS21710	COG0137	argininosuccinate synthase activity
H7F26_RS21715	COG0521	Mo-molybdopterin cofactor biosynthetic process
H7F26_RS21720	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H7F26_RS21725	COG0827	DNA restriction-modification system
H7F26_RS21730	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
H7F26_RS21735	COG3874	Sporulation protein YtfJ
H7F26_RS21745	COG1714	RDD family
H7F26_RS21750	COG0616	signal peptide processing