locus-tag	class	description
JVX94_RS00125	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
JVX94_RS00130	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JVX94_RS00135	COG1575	Belongs to the MenA family. Type 1 subfamily
JVX94_RS00140	COG1169	isochorismate synthase
JVX94_RS00145	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JVX94_RS00150	COG0596	Alpha beta hydrolase
JVX94_RS00155	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JVX94_RS00160	COG0318	PFAM AMP-dependent synthetase and ligase
JVX94_RS00165	COG4948	Mandelate Racemase Muconate Lactonizing
JVX94_RS00180	COG1294	oxidase, subunit
JVX94_RS00185	COG1271	oxidase subunit
JVX94_RS00190	COG0254	rRNA binding
JVX94_RS00195	COG0803	Belongs to the bacterial solute-binding protein 9 family
JVX94_RS00195	COG3443	Belongs to the bacterial solute-binding protein 9 family
JVX94_RS00200	COG0288	reversible hydration of carbon dioxide
JVX94_RS00205	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JVX94_RS00210	COG1854	S-ribosylhomocysteine lyase activity
JVX94_RS00225	COG0783	Belongs to the Dps family
JVX94_RS00235	COG4824	toxin secretion phage lysis holin
JVX94_RS00250	COG2310	stress, protein
JVX94_RS00255	COG0494	nUDIX hydrolase
JVX94_RS00260	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JVX94_RS00265	COG1116	anion transmembrane transporter activity
JVX94_RS00270	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JVX94_RS00290	COG1233	COG1233 Phytoene dehydrogenase and related
JVX94_RS00295	COG1506	peptidase
JVX94_RS00305	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JVX94_RS00310	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JVX94_RS00315	COG0367	asparagine synthase
JVX94_RS00320	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JVX94_RS00325	COG2267	carboxylic ester hydrolase activity
JVX94_RS00335	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
JVX94_RS00340	COG1242	4 iron, 4 sulfur cluster binding
JVX94_RS00355	COG1725	Transcriptional regulator
JVX94_RS00360	COG1131	(ABC) transporter
JVX94_RS00370	COG1136	(ABC) transporter
JVX94_RS00375	COG0577	efflux transmembrane transporter activity
JVX94_RS00380	COG2433	Pfam Transposase IS66
JVX94_RS00385	COG1366	Belongs to the anti-sigma-factor antagonist family
JVX94_RS00385	COG2202	Pas domain
JVX94_RS00395	COG0495	leucyl-tRNA aminoacylation
JVX94_RS00400	COG1073	alpha beta
JVX94_RS00405	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JVX94_RS00410	COG0395	ABC-type sugar transport system, permease component
JVX94_RS00415	COG1653	transport
JVX94_RS00420	COG0656	L-ascorbic acid biosynthetic process
JVX94_RS00425	COG2814	Major facilitator Superfamily
JVX94_RS00430	COG1733	regulation of RNA biosynthetic process
JVX94_RS00435	COG2207	Transcriptional regulator
JVX94_RS00440	COG4209	transmembrane transport
JVX94_RS00445	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
JVX94_RS00450	COG1653	transport
JVX94_RS00455	COG0673	inositol 2-dehydrogenase activity
JVX94_RS00460	COG5578	integral membrane protein
JVX94_RS00465	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JVX94_RS00475	COG3196	Protein conserved in bacteria
JVX94_RS00480	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JVX94_RS00490	COG2081	HI0933 family
JVX94_RS00495	COG2244	polysaccharide biosynthetic process
JVX94_RS00500	COG1187	pseudouridine synthase activity
JVX94_RS00505	COG1349	DNA-binding transcription factor activity
JVX94_RS00510	COG2252	PERMEase
JVX94_RS00515	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JVX94_RS00520	COG3340	Belongs to the peptidase S51 family
JVX94_RS00525	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JVX94_RS00530	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JVX94_RS00540	COG1597	lipid kinase activity
JVX94_RS00545	COG0510	thiamine kinase activity
JVX94_RS00555	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JVX94_RS00560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JVX94_RS00565	COG0281	malic enzyme
JVX94_RS00570	COG5584	Small secreted protein
JVX94_RS00575	COG1363	Peptidase, m42
JVX94_RS00590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JVX94_RS00595	COG4848	Belongs to the UPF0354 family
JVX94_RS00600	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JVX94_RS00605	COG1674	ftsk spoiiie
JVX94_RS00610	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JVX94_RS00615	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
JVX94_RS00620	COG4980	gas vesicle protein
JVX94_RS00625	COG3118	belongs to the thioredoxin family
JVX94_RS00630	COG1605	Chorismate mutase
JVX94_RS00630	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JVX94_RS00635	COG1609	Transcriptional regulator
JVX94_RS00640	COG0123	including yeast histone deacetylase and acetoin utilization protein
JVX94_RS00645	COG0517	IMP dehydrogenase activity
JVX94_RS00650	COG0454	-acetyltransferase
JVX94_RS00655	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JVX94_RS00660	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JVX94_RS00665	COG2329	Antibiotic biosynthesis monooxygenase
JVX94_RS00670	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
JVX94_RS00675	COG1335	isochorismatase
JVX94_RS00685	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JVX94_RS00690	COG1956	GAF domain-containing protein
JVX94_RS00695	COG1309	transcriptional regulator
JVX94_RS00700	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JVX94_RS00705	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JVX94_RS00710	COG1114	Component of the transport system for branched-chain amino acids
JVX94_RS00715	COG1114	Component of the transport system for branched-chain amino acids
JVX94_RS00720	COG1104	cysteine desulfurase activity
JVX94_RS00725	COG0301	tRNA thio-modification
JVX94_RS00735	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JVX94_RS00740	COG1279	arginine transmembrane transporter activity
JVX94_RS00750	COG2249	NAD(P)H dehydrogenase (quinone) activity
JVX94_RS00755	COG0402	S-adenosylhomocysteine deaminase activity
JVX94_RS00760	COG0577	efflux transmembrane transporter activity
JVX94_RS00765	COG1136	(ABC) transporter
JVX94_RS00770	COG1695	Transcriptional regulator
JVX94_RS00775	COG0772	Belongs to the SEDS family
JVX94_RS00780	COG0642	Histidine kinase
JVX94_RS00785	COG0745	RESPONSE REGULATOR receiver
JVX94_RS00790	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JVX94_RS00795	COG2197	response regulator
JVX94_RS00800	COG4585	Histidine kinase
JVX94_RS00805	COG3239	Fatty acid desaturase
JVX94_RS00815	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JVX94_RS00820	COG0616	signal peptide processing
JVX94_RS00825	COG1714	RDD family
JVX94_RS00835	COG3874	Sporulation protein YtfJ
JVX94_RS00840	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JVX94_RS00845	COG0827	DNA restriction-modification system
JVX94_RS00850	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JVX94_RS00855	COG0521	Mo-molybdopterin cofactor biosynthetic process
JVX94_RS00860	COG0137	argininosuccinate synthase activity
JVX94_RS00865	COG0165	Argininosuccinate lyase
JVX94_RS00875	COG1028	Short-chain dehydrogenase reductase Sdr
JVX94_RS00880	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JVX94_RS00885	COG4109	DRTGG domain
JVX94_RS00895	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JVX94_RS00915	COG0587	DNA-directed DNA polymerase activity
JVX94_RS00920	COG0281	malic enzyme
JVX94_RS00925	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JVX94_RS00930	COG0825	malonyl-CoA metabolic process
JVX94_RS00935	COG0205	6-phosphofructokinase activity
JVX94_RS00945	COG3030	protein affecting phage T7 exclusion by the F plasmid
JVX94_RS00950	COG0628	permease
JVX94_RS00955	COG2707	UPF0756 membrane protein
JVX94_RS00960	COG0372	Belongs to the citrate synthase family
JVX94_RS00965	COG0538	isocitrate dehydrogenase activity
JVX94_RS00970	COG0039	L-malate dehydrogenase activity
JVX94_RS00975	COG0745	RESPONSE REGULATOR receiver
JVX94_RS00980	COG5002	protein histidine kinase activity
JVX94_RS00985	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JVX94_RS00985	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JVX94_RS00990	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JVX94_RS00995	COG1971	Probably functions as a manganese efflux pump
JVX94_RS01000	COG0237	dephospho-CoA kinase activity
JVX94_RS01005	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JVX94_RS01010	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
JVX94_RS01020	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JVX94_RS01025	COG3611	Membrane attachment protein
JVX94_RS01030	COG1484	DNA-dependent DNA replication
JVX94_RS01035	COG0398	Pfam SNARE associated Golgi protein
JVX94_RS01045	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JVX94_RS01055	COG1011	Hydrolase
JVX94_RS01060	COG3275	phosphorelay sensor kinase activity
JVX94_RS01065	COG3279	Response regulator of the LytR AlgR family
JVX94_RS01075	COG1346	cytolysis
JVX94_RS01080	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JVX94_RS01085	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JVX94_RS01090	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JVX94_RS01095	COG3326	Membrane
JVX94_RS01105	COG1363	Peptidase, m42
JVX94_RS01110	COG1966	Carbon starvation protein
JVX94_RS01120	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JVX94_RS01125	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JVX94_RS01130	COG0072	phenylalanine-tRNA ligase activity
JVX94_RS01130	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JVX94_RS01135	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JVX94_RS01140	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JVX94_RS01145	COG1286	toxin biosynthetic process
JVX94_RS01150	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JVX94_RS01150	COG1796	DNA polymerase
JVX94_RS01155	COG1193	negative regulation of DNA recombination
JVX94_RS01160	COG3766	membrane
JVX94_RS01170	COG0318	PFAM AMP-dependent synthetase and ligase
JVX94_RS01175	COG1309	transcriptional regulator
JVX94_RS01180	COG1024	Enoyl-CoA hydratase
JVX94_RS01185	COG2086	electron transfer activity
JVX94_RS01190	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JVX94_RS01195	COG3534	alpha-L-arabinofuranosidase
JVX94_RS01200	COG3118	belongs to the thioredoxin family
JVX94_RS01205	COG0322	excinuclease ABC activity
JVX94_RS01210	COG0527	aspartate kinase activity
JVX94_RS01215	COG1719	4-vinyl reductase, 4VR
JVX94_RS01220	COG2009	succinate dehydrogenase
JVX94_RS01225	COG1053	succinate dehydrogenase
JVX94_RS01230	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JVX94_RS01235	COG0824	Thioesterase
JVX94_RS01245	COG2828	Protein conserved in bacteria
JVX94_RS01250	COG0583	DNA-binding transcription factor activity
JVX94_RS01255	COG2851	Citrate transporter
JVX94_RS01260	COG2197	response regulator
JVX94_RS01265	COG1846	Transcriptional regulator
JVX94_RS01270	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JVX94_RS01275	COG5401	PFAM Sporulation and spore germination
JVX94_RS01280	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JVX94_RS01285	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JVX94_RS01290	COG0622	Phosphoesterase
JVX94_RS01300	COG1028	Short-chain dehydrogenase reductase Sdr
JVX94_RS01315	COG0346	lactoylglutathione lyase activity
JVX94_RS01330	COG1696	Membrane protein involved in D-alanine export
JVX94_RS01335	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JVX94_RS01340	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JVX94_RS01345	COG3339	Conserved Protein
JVX94_RS01350	COG2706	6-phosphogluconolactonase activity
JVX94_RS01355	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JVX94_RS01360	COG0028	Belongs to the TPP enzyme family
JVX94_RS01365	COG0440	acetolactate synthase activity
JVX94_RS01370	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JVX94_RS01375	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JVX94_RS01380	COG0473	3-isopropylmalate dehydrogenase activity
JVX94_RS01385	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JVX94_RS01390	COG0066	3-isopropylmalate dehydratase activity
JVX94_RS01395	COG1477	protein flavinylation
JVX94_RS01395	COG0457	Tetratricopeptide repeat
JVX94_RS01400	COG0544	peptidyl-prolyl cis-trans isomerase activity
JVX94_RS01405	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JVX94_RS01410	COG1067	ATP-dependent peptidase activity
JVX94_RS01410	COG0470	DNA polymerase III
JVX94_RS01415	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JVX94_RS01420	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JVX94_RS01430	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JVX94_RS01435	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JVX94_RS01440	COG0181	hydroxymethylbilane synthase activity
JVX94_RS01445	COG1587	Uroporphyrinogen-III synthase
JVX94_RS01450	COG0113	porphobilinogen synthase activity
JVX94_RS01455	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JVX94_RS01460	COG1388	LysM domain
JVX94_RS01465	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JVX94_RS01475	COG0525	valine-tRNA ligase activity
JVX94_RS01480	COG0285	dihydrofolate synthase activity
JVX94_RS01485	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JVX94_RS01495	COG0424	maF-like protein
JVX94_RS01500	COG2003	Belongs to the UPF0758 family
JVX94_RS01505	COG1077	Cell shape determining protein MreB Mrl
JVX94_RS01515	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
JVX94_RS01520	COG0850	regulation of cytokinetic process
JVX94_RS01525	COG2894	cell division
JVX94_RS01530	COG0739	heme binding
JVX94_RS01535	COG1994	Peptidase M50
JVX94_RS01540	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JVX94_RS01545	COG2868	ribosomal protein
JVX94_RS01550	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JVX94_RS01555	COG3290	protein histidine kinase activity
JVX94_RS01560	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JVX94_RS01565	COG4492	Belongs to the UPF0735 family
JVX94_RS01570	COG0077	Prephenate dehydratase
JVX94_RS01575	COG1827	regulation of RNA biosynthetic process
JVX94_RS01580	COG1104	cysteine desulfurase activity
JVX94_RS01585	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
JVX94_RS01590	COG0157	Belongs to the NadC ModD family
JVX94_RS01595	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JVX94_RS01600	COG1388	LysM domain
JVX94_RS01615	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JVX94_RS01630	COG2112	serine threonine protein kinase
JVX94_RS01640	COG0632	four-way junction helicase activity
JVX94_RS01645	COG2255	four-way junction helicase activity
JVX94_RS01655	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JVX94_RS01660	COG0343	queuine tRNA-ribosyltransferase activity
JVX94_RS01665	COG1862	Preprotein translocase
JVX94_RS01675	COG2323	membrane
JVX94_RS01680	COG2244	polysaccharide biosynthetic process
JVX94_RS01690	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JVX94_RS01690	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JVX94_RS01695	COG0490	domain, Protein
JVX94_RS01700	COG5416	Lipopolysaccharide assembly protein A domain
JVX94_RS01705	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JVX94_RS01705	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JVX94_RS01710	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JVX94_RS01715	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JVX94_RS01720	COG1490	D-aminoacyl-tRNA deacylase activity
JVX94_RS01725	COG0860	N-Acetylmuramoyl-L-alanine amidase
JVX94_RS01725	COG3103	Sh3 type 3 domain protein
JVX94_RS01725	COG4991	sh3 domain protein
JVX94_RS01735	COG0124	histidyl-tRNA synthetase
JVX94_RS01750	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JVX94_RS01755	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JVX94_RS01760	COG1959	2 iron, 2 sulfur cluster binding
JVX94_RS01765	COG1104	cysteine desulfurase activity
JVX94_RS01770	COG0482	sulfurtransferase activity
JVX94_RS01775	COG0457	Tetratricopeptide repeat
JVX94_RS01780	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JVX94_RS01785	COG3881	PFAM PRC-barrel domain
JVX94_RS01800	COG0765	amino acid transport
JVX94_RS01805	COG0765	amino acid transport
JVX94_RS01810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JVX94_RS01815	COG1126	abc transporter atp-binding protein
JVX94_RS01820	COG0628	permease
JVX94_RS01825	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JVX94_RS01830	COG4472	Bacterial protein of unknown function (DUF965)
JVX94_RS01835	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JVX94_RS01840	COG3906	Belongs to the UPF0473 family
JVX94_RS01845	COG1268	BioY protein
JVX94_RS01850	COG0318	PFAM AMP-dependent synthetase and ligase
JVX94_RS01855	COG0183	Belongs to the thiolase family
JVX94_RS01860	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JVX94_RS01865	COG4122	O-methyltransferase activity
JVX94_RS01870	COG0826	peptidase U32
JVX94_RS01875	COG0826	peptidase U32
JVX94_RS01880	COG0572	uridine kinase
JVX94_RS01890	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JVX94_RS01895	COG0768	penicillin binding
JVX94_RS01910	COG2226	methyltransferase
JVX94_RS01915	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JVX94_RS01920	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JVX94_RS01925	COG0626	cystathionine gamma-synthase activity
JVX94_RS01950	COG2226	methyltransferase
JVX94_RS01955	COG1063	alcohol dehydrogenase
JVX94_RS01960	COG2226	methyltransferase
JVX94_RS01965	COG1131	(ABC) transporter
JVX94_RS01970	COG0842	Transport permease protein
JVX94_RS01970	COG1511	domain protein
JVX94_RS01975	COG0842	Transport permease protein
JVX94_RS01980	COG0583	DNA-binding transcription factor activity
JVX94_RS01985	COG1115	amino acid carrier protein
JVX94_RS01995	COG1028	Short-chain dehydrogenase reductase Sdr
JVX94_RS02005	COG1063	alcohol dehydrogenase
JVX94_RS02010	COG3546	catalase activity
JVX94_RS02020	COG0765	amino acid transport
JVX94_RS02025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JVX94_RS02030	COG1126	abc transporter atp-binding protein
JVX94_RS02035	COG1960	acyl-CoA dehydrogenase activity
JVX94_RS02040	COG2602	Beta-lactamase
JVX94_RS02060	COG1733	regulation of RNA biosynthetic process
JVX94_RS02065	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
JVX94_RS02070	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
JVX94_RS02080	COG1846	Transcriptional regulator
JVX94_RS02090	COG1609	Transcriptional regulator
JVX94_RS02105	COG2160	L-arabinose isomerase activity
JVX94_RS02125	COG1131	(ABC) transporter
JVX94_RS02160	COG0726	polysaccharide deacetylase
JVX94_RS02185	COG2318	DinB family
JVX94_RS02210	COG0457	Tetratricopeptide repeat
JVX94_RS02220	COG2755	lipolytic protein G-D-S-L family
JVX94_RS02235	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
JVX94_RS02240	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JVX94_RS02245	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JVX94_RS02250	COG1534	Rna-binding protein
JVX94_RS02255	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JVX94_RS02260	COG1713	HD superfamily hydrolase involved in NAD metabolism
JVX94_RS02265	COG0799	negative regulation of ribosome biogenesis
JVX94_RS02270	COG2226	methyltransferase
JVX94_RS02275	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JVX94_RS02280	COG1555	photosystem II stabilization
JVX94_RS02285	COG2131	deaminase
JVX94_RS02290	COG0658	competence protein
JVX94_RS02290	COG2333	competence protein COMEC
JVX94_RS02300	COG1466	dna polymerase III delta subunit
JVX94_RS02305	COG0268	Binds directly to 16S ribosomal RNA
JVX94_RS02310	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
JVX94_RS02315	COG0860	N-Acetylmuramoyl-L-alanine amidase
JVX94_RS02325	COG0481	GTPase activity
JVX94_RS02330	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JVX94_RS02335	COG1420	regulation of RNA biosynthetic process
JVX94_RS02340	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JVX94_RS02345	COG0443	Heat shock 70 kDa protein
JVX94_RS02350	COG0484	heat shock protein binding
JVX94_RS02355	COG2264	protein methyltransferase activity
JVX94_RS02360	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JVX94_RS02365	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JVX94_RS02370	COG1283	sodium-dependent phosphate transmembrane transporter activity
JVX94_RS02380	COG1610	YqeY-like protein
JVX94_RS02385	COG1030	water channel activity
JVX94_RS02390	COG4864	UPF0365 protein
JVX94_RS02405	COG0561	phosphatase activity
JVX94_RS02410	COG1702	phosphate starvation-inducible protein PhoH
JVX94_RS02415	COG1480	7TM receptor with intracellular HD hydrolase
JVX94_RS02420	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JVX94_RS02425	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JVX94_RS02430	COG0295	cytidine deaminase activity
JVX94_RS02435	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JVX94_RS02445	COG1381	Involved in DNA repair and RecF pathway recombination
JVX94_RS02450	COG0752	glycyl-tRNA synthetase alpha subunit
JVX94_RS02455	COG0751	glycine-tRNA ligase activity
JVX94_RS02460	COG0517	IMP dehydrogenase activity
JVX94_RS02465	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JVX94_RS02470	COG1671	Belongs to the UPF0178 family
JVX94_RS02475	COG0358	DNA primase activity
JVX94_RS02480	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JVX94_RS02485	COG2010	Cytochrome c
JVX94_RS02490	COG2384	SAM-dependent methyltransferase
JVX94_RS02495	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JVX94_RS02500	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JVX94_RS02510	COG0513	Belongs to the DEAD box helicase family
JVX94_RS02515	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JVX94_RS02525	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JVX94_RS02530	COG1121	(ABC) transporter
JVX94_RS02535	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JVX94_RS02540	COG0735	belongs to the Fur family
JVX94_RS02550	COG1940	carbohydrate kinase activity
JVX94_RS02555	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
JVX94_RS02560	COG4709	membrane
JVX94_RS02565	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JVX94_RS02570	COG1388	LysM domain
JVX94_RS02575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JVX94_RS02580	COG5521	maltodextrose utilization protein MalA
JVX94_RS02585	COG2839	Protein conserved in bacteria
JVX94_RS02590	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JVX94_RS02595	COG0477	Major facilitator Superfamily
JVX94_RS02600	COG0768	penicillin binding
JVX94_RS02605	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JVX94_RS02610	COG0573	inorganic phosphate transmembrane transporter activity
JVX94_RS02615	COG0581	inorganic phosphate transmembrane transporter activity
JVX94_RS02620	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JVX94_RS02625	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JVX94_RS02630	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JVX94_RS02640	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JVX94_RS02645	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JVX94_RS02655	COG0705	Rhomboid family
JVX94_RS02655	COG0457	Tetratricopeptide repeat
JVX94_RS02660	COG4483	Protein conserved in bacteria
JVX94_RS02665	COG1940	carbohydrate kinase activity
JVX94_RS02670	COG1368	sulfuric ester hydrolase activity
JVX94_RS02675	COG2866	Carboxypeptidase
JVX94_RS02680	COG2814	Major facilitator Superfamily
JVX94_RS02685	COG0011	TIGRFAM Protein of
JVX94_RS02695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JVX94_RS02705	COG1393	Belongs to the ArsC family
JVX94_RS02715	COG1366	Belongs to the anti-sigma-factor antagonist family
JVX94_RS02720	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JVX94_RS02725	COG1459	type II secretion system
JVX94_RS02730	COG4537	Required for transformation and DNA binding
JVX94_RS02735	COG4970	Tfp pilus assembly protein FimT
JVX94_RS02765	COG0681	Belongs to the peptidase S26 family
JVX94_RS02790	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JVX94_RS02795	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JVX94_RS02800	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JVX94_RS02805	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JVX94_RS02810	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JVX94_RS02815	COG0095	Lipoate-protein ligase
JVX94_RS02820	COG1321	iron dependent repressor
JVX94_RS02825	COG1752	Esterase of the alpha-beta hydrolase superfamily
JVX94_RS02835	COG3872	metal-dependent enzyme
JVX94_RS02845	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JVX94_RS02850	COG0006	proline dipeptidase activity
JVX94_RS02855	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JVX94_RS02865	COG3854	ATPases associated with a variety of cellular activities
JVX94_RS02905	COG0511	ligase activity, forming carbon-carbon bonds
JVX94_RS02910	COG0439	Biotin carboxylase
JVX94_RS02915	COG1302	Protein conserved in bacteria
JVX94_RS02920	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JVX94_RS02925	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JVX94_RS02930	COG1570	exodeoxyribonuclease VII activity
JVX94_RS02935	COG1722	exodeoxyribonuclease VII activity
JVX94_RS02940	COG0142	geranyltranstransferase activity
JVX94_RS02945	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JVX94_RS02950	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
JVX94_RS02955	COG1438	arginine binding
JVX94_RS02960	COG0497	DNA recombination
JVX94_RS02965	COG0750	zinc metalloprotease
JVX94_RS02970	COG0745	RESPONSE REGULATOR receiver
JVX94_RS02975	COG0457	Tetratricopeptide repeat
JVX94_RS02980	COG0584	glycerophosphoryl diester phosphodiesterase
JVX94_RS02990	COG3829	transcription factor binding
JVX94_RS02990	COG3290	protein histidine kinase activity
JVX94_RS02995	COG0280	phosphate acetyltransferase
JVX94_RS03000	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JVX94_RS03005	COG3426	butyrate kinase activity
JVX94_RS03010	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JVX94_RS03015	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JVX94_RS03020	COG0022	dehydrogenase e1 component
JVX94_RS03025	COG0508	dehydrogenase complex catalyzes the overall conversion of
JVX94_RS03035	COG1597	lipid kinase activity
JVX94_RS03045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JVX94_RS03050	COG0765	amino acid transport
JVX94_RS03055	COG1126	abc transporter atp-binding protein
JVX94_RS03060	COG4129	membrane
JVX94_RS03065	COG1376	ErfK ybiS ycfS ynhG family protein
JVX94_RS03075	COG0346	lactoylglutathione lyase activity
JVX94_RS03080	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JVX94_RS03085	COG2195	Cleaves the N-terminal amino acid of tripeptides
JVX94_RS03095	COG0706	membrane insertase activity
JVX94_RS03110	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JVX94_RS03115	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JVX94_RS03125	COG1028	Short-chain dehydrogenase reductase Sdr
JVX94_RS03130	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JVX94_RS03135	COG1447	Phosphotransferase system cellobiose-specific component IIA
JVX94_RS03140	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JVX94_RS03145	COG2723	6-phospho-beta-galactosidase activity
JVX94_RS03150	COG2188	Transcriptional regulator
JVX94_RS03155	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JVX94_RS03165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JVX94_RS03170	COG0596	Alpha beta hydrolase
JVX94_RS03175	COG1902	pentaerythritol trinitrate reductase activity
JVX94_RS03180	COG4187	Peptidase family M20/M25/M40
JVX94_RS03190	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JVX94_RS03195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JVX94_RS03200	COG0300	oxidoreductase activity
JVX94_RS03205	COG0446	pyridine nucleotide-disulphide oxidoreductase
JVX94_RS03210	COG1072	(Pantothenic acid kinase))
JVX94_RS03215	COG2211	Major facilitator Superfamily
JVX94_RS03225	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JVX94_RS03235	COG0456	acetyltransferase
JVX94_RS03240	COG0456	acetyltransferase
JVX94_RS03240	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JVX94_RS03245	COG4918	Iron-sulphur cluster biosynthesis
JVX94_RS03255	COG0457	Tetratricopeptide repeat
JVX94_RS03260	COG1073	alpha beta
JVX94_RS03270	COG0667	Aldo Keto reductase
JVX94_RS03275	COG0494	nUDIX hydrolase
JVX94_RS03280	COG1379	DNA repair
JVX94_RS03285	COG2153	protein acetylation
JVX94_RS03295	COG1404	Belongs to the peptidase S8 family
JVX94_RS03300	COG1300	Membrane
JVX94_RS03305	COG0735	belongs to the Fur family
JVX94_RS03315	COG4974	Belongs to the 'phage' integrase family
JVX94_RS03320	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JVX94_RS03325	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JVX94_RS03330	COG1686	Belongs to the peptidase S11 family
JVX94_RS03340	COG2172	sigma factor antagonist activity
JVX94_RS03345	COG1191	sigma factor activity
JVX94_RS03365	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JVX94_RS03380	COG0697	spore germination
JVX94_RS03385	COG0019	diaminopimelate decarboxylase activity
JVX94_RS03390	COG4086	secreted protein
JVX94_RS03395	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JVX94_RS03400	COG2814	Major facilitator Superfamily
JVX94_RS03405	COG1309	transcriptional regulator
JVX94_RS03420	COG0307	riboflavin synthase, alpha
JVX94_RS03425	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JVX94_RS03425	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JVX94_RS03430	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JVX94_RS03435	COG0456	acetyltransferase
JVX94_RS03440	COG1547	Domain of unknown function (DUF309)
JVX94_RS03450	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JVX94_RS03455	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JVX94_RS03465	COG1686	Belongs to the peptidase S11 family
JVX94_RS03470	COG2715	membrane protein required for spore maturation
JVX94_RS03475	COG0700	Nucleoside recognition
JVX94_RS03480	COG1187	pseudouridine synthase activity
JVX94_RS03485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JVX94_RS03490	COG1333	cytochrome c biogenesis protein
JVX94_RS03495	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JVX94_RS03500	COG0745	RESPONSE REGULATOR receiver
JVX94_RS03505	COG5002	protein histidine kinase activity
JVX94_RS03510	COG1595	DNA-templated transcription, initiation
JVX94_RS03520	COG0791	NLP P60 protein
JVX94_RS03520	COG1388	LysM domain
JVX94_RS03525	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JVX94_RS03530	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JVX94_RS03535	COG1141	Ferredoxin
JVX94_RS03540	COG4955	Helix-turn-helix domain
JVX94_RS03545	COG0514	ATP-dependent DNA helicase (RecQ)
JVX94_RS03550	COG1266	CAAX protease self-immunity
JVX94_RS03555	COG1388	LysM domain
JVX94_RS03565	COG1408	metallophosphoesterase
JVX94_RS03570	COG4862	establishment of competence for transformation
JVX94_RS03575	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JVX94_RS03580	COG0492	ferredoxin-NADP+ reductase activity
JVX94_RS03585	COG2339	peptidase activity
JVX94_RS03590	COG3409	Peptidoglycan-binding domain 1 protein
JVX94_RS03590	COG3773	Cell wall hydrolase
JVX94_RS03595	COG2959	enzyme of heme biosynthesis
JVX94_RS03600	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
JVX94_RS03610	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JVX94_RS03615	COG0539	negative regulation of cytoplasmic translation
JVX94_RS03620	COG1304	FMN binding
JVX94_RS03645	COG1160	GTP binding
JVX94_RS03650	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JVX94_RS03665	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JVX94_RS03670	COG0776	regulation of translation
JVX94_RS03675	COG0302	gtp cyclohydrolase
JVX94_RS03685	COG0142	geranyltranstransferase activity
JVX94_RS03690	COG2226	methyltransferase
JVX94_RS03695	COG0142	geranyltranstransferase activity
JVX94_RS03700	COG0105	UTP biosynthetic process
JVX94_RS03705	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JVX94_RS03710	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JVX94_RS03715	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JVX94_RS03720	COG4401	Chorismate mutase type I
JVX94_RS03735	COG0134	indole-3-glycerol-phosphate synthase activity
JVX94_RS03740	COG0135	phosphoribosylanthranilate isomerase activity
JVX94_RS03745	COG0133	tryptophan synthase activity
JVX94_RS03750	COG0159	tryptophan synthase activity
JVX94_RS03755	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JVX94_RS03760	COG0287	Prephenate dehydrogenase
JVX94_RS03765	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JVX94_RS03770	COG0457	Tetratricopeptide repeat
JVX94_RS03775	COG5582	Belongs to the UPF0302 family
JVX94_RS03785	COG0723	plastoquinol--plastocyanin reductase activity
JVX94_RS03790	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JVX94_RS03795	COG2010	Cytochrome c
JVX94_RS03795	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JVX94_RS03800	COG4347	Protein of unknown function (DUF1405)
JVX94_RS03810	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JVX94_RS03815	COG1694	Mazg nucleotide pyrophosphohydrolase
JVX94_RS03820	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JVX94_RS03825	COG1803	Methylglyoxal synthase
JVX94_RS03830	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JVX94_RS03835	COG0438	transferase activity, transferring glycosyl groups
JVX94_RS03840	COG0617	tRNA 3'-terminal CCA addition
JVX94_RS03850	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JVX94_RS03855	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JVX94_RS03860	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JVX94_RS03865	COG1199	ATP-dependent helicase activity
JVX94_RS03865	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JVX94_RS03875	COG5353	protein conserved in bacteria
JVX94_RS03880	COG0017	Asparaginyl-tRNA synthetase
JVX94_RS03885	COG3935	DnaD domain protein
JVX94_RS03890	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JVX94_RS03900	COG4499	WXG100 protein secretion system (Wss), protein YukC
JVX94_RS03900	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JVX94_RS03905	COG3331	DNA recombination
JVX94_RS03935	COG0071	Belongs to the small heat shock protein (HSP20) family
JVX94_RS03940	COG2190	(PTS) system
JVX94_RS03945	COG1902	pentaerythritol trinitrate reductase activity
JVX94_RS03950	COG1111	helicase
JVX94_RS03950	COG1205	dead DEAH box helicase
JVX94_RS03955	COG3359	exonuclease
JVX94_RS03965	COG4474	Belongs to the UPF0398 family
JVX94_RS03970	COG3599	regulation of cell shape
JVX94_RS03980	COG0116	Belongs to the methyltransferase superfamily
JVX94_RS03990	COG1199	ATP-dependent helicase activity
JVX94_RS03995	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
JVX94_RS04000	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JVX94_RS04005	COG2233	PERMEase
JVX94_RS04010	COG0726	polysaccharide deacetylase
JVX94_RS04015	COG3424	synthase
JVX94_RS04020	COG1755	Isoprenylcysteine carboxyl methyltransferase
JVX94_RS04030	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JVX94_RS04040	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JVX94_RS04050	COG0328	RNA-DNA hybrid ribonuclease activity
JVX94_RS04055	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JVX94_RS04060	COG0328	RNA-DNA hybrid ribonuclease activity
JVX94_RS04075	COG1278	Cold shock
JVX94_RS04085	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JVX94_RS04090	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
JVX94_RS04095	COG2759	Belongs to the formate--tetrahydrofolate ligase family
JVX94_RS04100	COG0386	Belongs to the glutathione peroxidase family
JVX94_RS04105	COG1418	mRNA catabolic process
JVX94_RS04110	COG1413	lyase activity
JVX94_RS04115	COG0129	dihydroxy-acid dehydratase activity
JVX94_RS04125	COG2136	Putative SAM-dependent methyltransferase
JVX94_RS04125	COG2521	methyltransferase
JVX94_RS04135	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JVX94_RS04140	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JVX94_RS04145	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JVX94_RS04150	COG0204	Acyl-transferase
JVX94_RS04155	COG1272	protein, Hemolysin III
JVX94_RS04160	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JVX94_RS04165	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JVX94_RS04180	COG1999	signal sequence binding
JVX94_RS04185	COG2755	lipolytic protein G-D-S-L family
JVX94_RS04190	COG4698	Protein conserved in bacteria
JVX94_RS04210	COG1846	Transcriptional regulator
JVX94_RS04215	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JVX94_RS04220	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JVX94_RS04225	COG1086	Polysaccharide biosynthesis protein
JVX94_RS04235	COG4641	Protein conserved in bacteria
JVX94_RS04250	COG0463	Glycosyl transferase, family 2
JVX94_RS04255	COG3829	transcription factor binding
JVX94_RS04260	COG1509	lysine 2,3-aminomutase activity
JVX94_RS04270	COG4479	Belongs to the UPF0346 family
JVX94_RS04285	COG0671	phosphoesterase, PA-phosphatase related
JVX94_RS04295	COG0813	purine-nucleoside phosphorylase activity
JVX94_RS04300	COG1876	peptidase activity
JVX94_RS04310	COG2226	methyltransferase
JVX94_RS04315	COG0793	Belongs to the peptidase S41A family
JVX94_RS04315	COG3409	Peptidoglycan-binding domain 1 protein
JVX94_RS04320	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JVX94_RS04325	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JVX94_RS04335	COG0778	Nitroreductase
JVX94_RS04340	COG1733	regulation of RNA biosynthetic process
JVX94_RS04355	COG2962	Rard protein
JVX94_RS04365	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JVX94_RS04370	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JVX94_RS04380	COG0534	Mate efflux family protein
JVX94_RS04385	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JVX94_RS04390	COG1388	LysM domain
JVX94_RS04390	COG0791	NLP P60 protein
JVX94_RS04395	COG2032	superoxide dismutase activity
JVX94_RS04400	COG0714	Associated with various cellular activities
JVX94_RS04405	COG4548	von Willebrand factor, type A
JVX94_RS04410	COG0567	Dehydrogenase, E1 component
JVX94_RS04415	COG0508	dehydrogenase complex catalyzes the overall conversion of
JVX94_RS04420	COG0385	Bile acid
JVX94_RS04425	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JVX94_RS04430	COG1657	PFAM Prenyltransferase squalene oxidase
JVX94_RS04435	COG1012	belongs to the aldehyde dehydrogenase family
JVX94_RS04460	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JVX94_RS04470	COG0514	ATP-dependent DNA helicase (RecQ)
JVX94_RS04475	COG3584	3D domain protein
JVX94_RS04475	COG1388	LysM domain
JVX94_RS04485	COG2322	membrane
JVX94_RS04490	COG0372	Belongs to the citrate synthase family
JVX94_RS04495	COG2079	MmgE PrpD family protein
JVX94_RS04500	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JVX94_RS04505	COG0741	lytic transglycosylase activity
JVX94_RS04510	COG0531	amino acid
JVX94_RS04515	COG0640	Transcriptional regulator
JVX94_RS04525	COG2378	regulation of single-species biofilm formation
JVX94_RS04530	COG3708	Transcriptional regulator
JVX94_RS04535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JVX94_RS04540	COG1309	transcriptional regulator
JVX94_RS04560	COG1994	Peptidase M50
JVX94_RS04565	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JVX94_RS04570	COG2211	Major facilitator Superfamily
JVX94_RS04580	COG1940	carbohydrate kinase activity
JVX94_RS04585	COG2115	Belongs to the xylose isomerase family
JVX94_RS04590	COG1070	Carbohydrate kinase
JVX94_RS04600	COG0243	molybdopterin cofactor binding
JVX94_RS04615	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JVX94_RS04620	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JVX94_RS04625	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JVX94_RS04630	COG0454	-acetyltransferase
JVX94_RS04635	COG0789	Transcriptional regulator
JVX94_RS04635	COG4978	Transcriptional regulator
JVX94_RS04640	COG1132	(ABC) transporter
JVX94_RS04650	COG0583	DNA-binding transcription factor activity
JVX94_RS04655	COG0070	glutamate synthase
JVX94_RS04655	COG0069	glutamate synthase activity
JVX94_RS04655	COG0067	glutamate synthase
JVX94_RS04660	COG0493	'glutamate synthase
JVX94_RS04665	COG2223	nitrite transmembrane transporter activity
JVX94_RS04670	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JVX94_RS04675	COG0243	molybdopterin cofactor binding
JVX94_RS04680	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JVX94_RS04685	COG2146	nitrite reductase [NAD(P)H] activity
JVX94_RS04690	COG2323	membrane
JVX94_RS04695	COG4677	pectinesterase activity
JVX94_RS04700	COG2027	D-alanyl-D-alanine carboxypeptidase
JVX94_RS04705	COG0534	Mate efflux family protein
JVX94_RS04720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JVX94_RS04730	COG1587	Uroporphyrinogen-III synthase
JVX94_RS04735	COG0586	Pfam SNARE associated Golgi protein
JVX94_RS04740	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JVX94_RS04745	COG2246	polysaccharide biosynthetic process
JVX94_RS04750	COG0166	Belongs to the GPI family
JVX94_RS04775	COG0247	lactate metabolic process
JVX94_RS04780	COG0277	FAD linked oxidase domain protein
JVX94_RS04785	COG3835	regulator
JVX94_RS04795	COG1349	DNA-binding transcription factor activity
JVX94_RS04800	COG2365	Tyrosine phosphatase family
JVX94_RS04805	COG1649	PFAM Uncharacterised BCR, COG1649
JVX94_RS04810	COG1960	acyl-CoA dehydrogenase activity
JVX94_RS04815	COG0318	PFAM AMP-dependent synthetase and ligase
JVX94_RS04820	COG0439	Biotin carboxylase
JVX94_RS04825	COG0511	ligase activity, forming carbon-carbon bonds
JVX94_RS04830	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JVX94_RS04835	COG1024	Enoyl-CoA hydratase
JVX94_RS04840	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JVX94_RS04845	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JVX94_RS04850	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JVX94_RS04855	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JVX94_RS04885	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JVX94_RS04895	COG1105	Belongs to the carbohydrate kinase PfkB family
JVX94_RS04900	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JVX94_RS04900	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JVX94_RS04900	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JVX94_RS04905	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JVX94_RS04905	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JVX94_RS04905	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JVX94_RS04915	COG2814	Major facilitator Superfamily
JVX94_RS04920	COG1846	Transcriptional regulator
JVX94_RS04960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JVX94_RS04965	COG0456	acetyltransferase
JVX94_RS04975	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JVX94_RS04990	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JVX94_RS04995	COG1609	Transcriptional regulator
JVX94_RS05000	COG1653	transport
JVX94_RS05005	COG1175	transmembrane transport
JVX94_RS05010	COG0395	ABC-type sugar transport system, permease component
JVX94_RS05015	COG1486	melibiose metabolic process
JVX94_RS05020	COG1012	belongs to the aldehyde dehydrogenase family
JVX94_RS05025	COG3507	Belongs to the glycosyl hydrolase 43 family
JVX94_RS05035	COG0745	RESPONSE REGULATOR receiver
JVX94_RS05040	COG2205	protein histidine kinase activity
JVX94_RS05050	COG0789	Transcriptional regulator
JVX94_RS05055	COG0657	acetylesterase activity
JVX94_RS05060	COG0583	DNA-binding transcription factor activity
JVX94_RS05075	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JVX94_RS05115	COG0251	oxidation-reduction process
JVX94_RS05120	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JVX94_RS05125	COG2409	Drug exporters of the RND superfamily
JVX94_RS05130	COG4585	Histidine kinase
JVX94_RS05135	COG2197	response regulator
JVX94_RS05145	COG1733	regulation of RNA biosynthetic process
JVX94_RS05150	COG2249	NAD(P)H dehydrogenase (quinone) activity
JVX94_RS05170	COG1904	glucuronate isomerase
JVX94_RS05180	COG0673	inositol 2-dehydrogenase activity
JVX94_RS05185	COG1802	Transcriptional regulator
JVX94_RS05190	COG1312	Catalyzes the dehydration of D-mannonate
JVX94_RS05195	COG1028	Short-chain dehydrogenase reductase Sdr
JVX94_RS05205	COG0738	Major facilitator superfamily
JVX94_RS05220	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JVX94_RS05225	COG0187	DNA topoisomerase II activity
JVX94_RS05230	COG1832	CoA-binding protein
JVX94_RS05235	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JVX94_RS05240	COG4841	protein insertion into membrane
JVX94_RS05250	COG0824	Thioesterase
JVX94_RS05270	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JVX94_RS05275	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JVX94_RS05290	COG0071	Belongs to the small heat shock protein (HSP20) family
JVX94_RS05300	COG4846	Membrane protein involved in cytochrome C biogenesis
JVX94_RS05305	COG0785	Cytochrome C biogenesis protein
JVX94_RS05315	COG3763	UPF0154 protein
JVX94_RS05325	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JVX94_RS05330	COG4224	UPF0291 protein
JVX94_RS05335	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JVX94_RS05340	COG1388	LysM domain
JVX94_RS05345	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JVX94_RS05365	COG1366	Belongs to the anti-sigma-factor antagonist family
JVX94_RS05370	COG3209	COG3209 Rhs family protein
JVX94_RS05375	COG3591	Belongs to the peptidase S1B family
JVX94_RS05380	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JVX94_RS05380	COG2124	cytochrome p450
JVX94_RS05385	COG1309	transcriptional regulator
JVX94_RS05390	COG2323	membrane
JVX94_RS05410	COG1556	Lactate utilization protein
JVX94_RS05415	COG1139	Iron-sulfur cluster binding protein
JVX94_RS05420	COG0247	lactate metabolic process
JVX94_RS05425	COG0702	epimerase
JVX94_RS05430	COG1959	2 iron, 2 sulfur cluster binding
JVX94_RS05435	COG0346	lactoylglutathione lyase activity
JVX94_RS05440	COG4876	unkown
JVX94_RS05445	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
JVX94_RS05450	COG3285	dna ligase
JVX94_RS05450	COG1793	dna ligase
JVX94_RS05455	COG3619	membrane
JVX94_RS05465	COG0457	Tetratricopeptide repeat
JVX94_RS05470	COG5646	InterPro IPR014922
JVX94_RS05495	COG5444	nuclease activity
JVX94_RS05515	COG5444	nuclease activity
JVX94_RS05520	COG0457	Tetratricopeptide repeat
JVX94_RS05545	COG4282	regulation of fungal-type cell wall biogenesis
JVX94_RS05560	COG0860	N-Acetylmuramoyl-L-alanine amidase
JVX94_RS05565	COG4824	toxin secretion phage lysis holin
JVX94_RS05590	COG1705	Flagellar rod assembly protein muramidase FlgJ
JVX94_RS05665	COG4626	Terminase
JVX94_RS05665	COG1802	Transcriptional regulator
JVX94_RS05710	COG1595	DNA-templated transcription, initiation
JVX94_RS05815	COG4974	Belongs to the 'phage' integrase family
JVX94_RS05820	COG0174	glutamine synthetase
JVX94_RS05825	COG0789	Transcriptional regulator
JVX94_RS05830	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
JVX94_RS05835	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JVX94_RS05840	COG0464	growth
JVX94_RS05845	COG0860	N-Acetylmuramoyl-L-alanine amidase
JVX94_RS05850	COG4112	unkown
JVX94_RS05855	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JVX94_RS05860	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JVX94_RS05865	COG1780	Probably involved in ribonucleotide reductase function
JVX94_RS05880	COG1923	regulation of RNA biosynthetic process
JVX94_RS05885	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JVX94_RS05910	COG2076	Multidrug Resistance protein
JVX94_RS05915	COG1764	response to oxidative stress
JVX94_RS05920	COG4195	phage-related replication protein
JVX94_RS05925	COG1404	Belongs to the peptidase S8 family
JVX94_RS05930	COG0457	Tetratricopeptide repeat
JVX94_RS05935	COG4195	phage-related replication protein
JVX94_RS05940	COG1329	Transcriptional regulator
JVX94_RS05955	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JVX94_RS05960	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JVX94_RS05970	COG4550	Control of competence regulator ComK, YlbF/YmcA
JVX94_RS05975	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JVX94_RS05980	COG0156	8-amino-7-oxononanoate synthase activity
JVX94_RS05985	COG1063	alcohol dehydrogenase
JVX94_RS05990	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JVX94_RS05995	COG2359	stage V sporulation protein S
JVX94_RS06000	COG1692	metallophosphoesterase
JVX94_RS06005	COG1418	mRNA catabolic process
JVX94_RS06010	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JVX94_RS06015	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JVX94_RS06020	COG1058	Belongs to the CinA family
JVX94_RS06020	COG1546	Belongs to the CinA family
JVX94_RS06025	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JVX94_RS06030	COG1426	Protein conserved in bacteria
JVX94_RS06045	COG0300	oxidoreductase activity
JVX94_RS06050	COG1033	growth of symbiont in host cell
JVX94_RS06050	COG2409	Drug exporters of the RND superfamily
JVX94_RS06060	COG0612	Peptidase, M16
JVX94_RS06065	COG0612	Peptidase, M16
JVX94_RS06070	COG1033	growth of symbiont in host cell
JVX94_RS06070	COG2409	Drug exporters of the RND superfamily
JVX94_RS06075	COG2814	Major facilitator Superfamily
JVX94_RS06080	COG2188	Transcriptional regulator
JVX94_RS06085	COG4980	gas vesicle protein
JVX94_RS06085	COG1674	ftsk spoiiie
JVX94_RS06095	COG0740	serine-type endopeptidase activity
JVX94_RS06100	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JVX94_RS06110	COG0527	aspartate kinase activity
JVX94_RS06115	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JVX94_RS06120	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JVX94_RS06125	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JVX94_RS06130	COG1873	PFAM PRC-barrel domain
JVX94_RS06135	COG0367	asparagine synthase
JVX94_RS06180	COG1260	myo-inositol-1-phosphate synthase
JVX94_RS06185	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JVX94_RS06190	COG1028	Short-chain dehydrogenase reductase Sdr
JVX94_RS06195	COG1028	Short-chain dehydrogenase reductase Sdr
JVX94_RS06210	COG2255	four-way junction helicase activity
JVX94_RS06220	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
JVX94_RS06255	COG1132	(ABC) transporter
JVX94_RS06260	COG1132	(ABC) transporter
JVX94_RS06270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JVX94_RS06275	COG0612	Peptidase, M16
JVX94_RS06280	COG0726	polysaccharide deacetylase
JVX94_RS06285	COG1185	polyribonucleotide nucleotidyltransferase activity
JVX94_RS06290	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JVX94_RS06295	COG0196	riboflavin kinase activity
JVX94_RS06300	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JVX94_RS06305	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JVX94_RS06310	COG1550	Protein conserved in bacteria
JVX94_RS06315	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JVX94_RS06320	COG1358	cellular component organization or biogenesis
JVX94_RS06325	COG2740	Nucleic-acid-binding protein implicated in transcription termination
JVX94_RS06330	COG0195	Participates in both transcription termination and antitermination
JVX94_RS06335	COG0779	Required for maturation of 30S ribosomal subunits
JVX94_RS06385	COG1131	(ABC) transporter
JVX94_RS06420	COG2176	DNA-directed DNA polymerase activity
JVX94_RS06425	COG0442	prolyl-tRNA aminoacylation
JVX94_RS06430	COG0750	zinc metalloprotease
JVX94_RS06435	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JVX94_RS06440	COG4589	Belongs to the CDS family
JVX94_RS06445	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JVX94_RS06450	COG0233	cytoplasmic translational termination
JVX94_RS06455	COG0528	UMP kinase activity
JVX94_RS06460	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JVX94_RS06475	COG1191	sigma factor activity
JVX94_RS06480	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
JVX94_RS06485	COG1776	CheC inhibitor of MCP methylation
JVX94_RS06490	COG0835	chemotaxis
JVX94_RS06495	COG0643	Histidine kinase
JVX94_RS06495	COG2198	Histidine kinase
JVX94_RS06500	COG2201	protein-glutamate methylesterase activity
JVX94_RS06505	COG0455	bacterial-type flagellum organization
JVX94_RS06510	COG1419	protein localization to endoplasmic reticulum
JVX94_RS06515	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JVX94_RS06520	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JVX94_RS06525	COG1684	flagellar biosynthetic protein fliR
JVX94_RS06530	COG1987	bacterial-type flagellum assembly
JVX94_RS06535	COG1338	Plays a role in the flagellum-specific transport system
JVX94_RS06540	COG3190	flagellar
JVX94_RS06545	COG2201	protein-glutamate methylesterase activity
JVX94_RS06550	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JVX94_RS06550	COG1776	CheC inhibitor of MCP methylation
JVX94_RS06555	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JVX94_RS06560	COG1580	Controls the rotational direction of flagella during chemotaxis
JVX94_RS06565	COG1582	Flagellar protein (FlbD)
JVX94_RS06570	COG4786	Flagellar basal body rod
JVX94_RS06575	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
JVX94_RS06580	COG3144	bacterial-type flagellum assembly
JVX94_RS06585	COG3334	PFAM MgtE intracellular
JVX94_RS06590	COG2882	bacterial-type flagellum organization
JVX94_RS06595	COG1157	protein secretion by the type III secretion system
JVX94_RS06600	COG1317	bacterial-type flagellum organization
JVX94_RS06605	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JVX94_RS06610	COG1766	The M ring may be actively involved in energy transduction
JVX94_RS06615	COG1677	Flagellar hook-basal body complex protein FliE
JVX94_RS06620	COG1558	bacterial-type flagellum-dependent cell motility
JVX94_RS06625	COG1815	bacterial-type flagellum-dependent cell motility
JVX94_RS06630	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JVX94_RS06635	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JVX94_RS06640	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JVX94_RS06645	COG4974	Belongs to the 'phage' integrase family
JVX94_RS06650	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JVX94_RS06655	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JVX94_RS06660	COG0758	DNA mediated transformation
JVX94_RS06665	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JVX94_RS06670	COG0045	succinate-CoA ligase (ADP-forming) activity
JVX94_RS06675	COG2257	FlhB HrpN YscU SpaS Family
JVX94_RS06685	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JVX94_RS06690	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JVX94_RS06695	COG0335	large ribosomal subunit rRNA binding
JVX94_RS06700	COG0336	Belongs to the RNA methyltransferase TrmD family
JVX94_RS06705	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JVX94_RS06715	COG1837	Belongs to the UPF0109 family
JVX94_RS06720	COG0228	four-way junction DNA binding
JVX94_RS06725	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JVX94_RS06730	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JVX94_RS06735	COG0552	protein localization to endoplasmic reticulum
JVX94_RS06740	COG1196	nuclear chromosome segregation
JVX94_RS06750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JVX94_RS06755	COG1028	Short-chain dehydrogenase reductase Sdr
JVX94_RS06760	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JVX94_RS06765	COG0416	fatty acid biosynthetic process
JVX94_RS06770	COG1349	DNA-binding transcription factor activity
JVX94_RS06775	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JVX94_RS06780	COG1760	l-serine dehydratase
JVX94_RS06785	COG1760	l-serine dehydratase
JVX94_RS06790	COG1461	Dihydroxyacetone kinase
JVX94_RS06795	COG1302	Protein conserved in bacteria
JVX94_RS06800	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JVX94_RS06810	COG1564	THIamine pyrophosphokinase
JVX94_RS06815	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JVX94_RS06820	COG1162	GTPase activity
JVX94_RS06825	COG0515	serine threonine protein kinase
JVX94_RS06825	COG2815	serine threonine protein kinase
JVX94_RS06830	COG0631	protein serine/threonine phosphatase activity
JVX94_RS06835	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JVX94_RS06840	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JVX94_RS06840	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JVX94_RS06845	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JVX94_RS06850	COG0242	peptide deformylase activity
JVX94_RS06855	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JVX94_RS06860	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JVX94_RS06865	COG1758	RNA polymerase activity
JVX94_RS06870	COG0194	GDP metabolic process
JVX94_RS06875	COG2052	Domain of unknown function (DUF370)
JVX94_RS06880	COG1561	YicC-like family, N-terminal region
JVX94_RS06885	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JVX94_RS06895	COG1648	precorrin-2 dehydrogenase activity
JVX94_RS06900	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
JVX94_RS06905	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JVX94_RS06910	COG0529	Catalyzes the synthesis of activated sulfate
JVX94_RS06915	COG2046	Belongs to the sulfate adenylyltransferase family
JVX94_RS06920	COG0306	phosphate transporter
JVX94_RS06925	COG0175	sulfate reduction
JVX94_RS06935	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JVX94_RS06940	COG0284	orotidine-5'-phosphate decarboxylase activity
JVX94_RS06945	COG0167	dihydroorotate dehydrogenase activity
JVX94_RS06950	COG0543	2 iron, 2 sulfur cluster binding
JVX94_RS06955	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JVX94_RS06960	COG0505	Belongs to the CarA family
JVX94_RS06965	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JVX94_RS06970	COG0540	Belongs to the ATCase OTCase family
JVX94_RS06975	COG2233	PERMEase
JVX94_RS06980	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JVX94_RS06985	COG0564	pseudouridine synthase activity
JVX94_RS06990	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JVX94_RS06995	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JVX94_RS07000	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JVX94_RS07005	COG3599	regulation of cell shape
JVX94_RS07010	COG2302	S4 RNA-binding domain
JVX94_RS07015	COG0762	integral membrane protein
JVX94_RS07020	COG1799	cell septum assembly
JVX94_RS07025	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JVX94_RS07030	COG1496	oxidoreductase activity
JVX94_RS07035	COG1873	PFAM PRC-barrel domain
JVX94_RS07040	COG1119	ATPase activity
JVX94_RS07050	COG3732	PTS system glucitol sorbitol-specific
JVX94_RS07055	COG3730	PTS system glucitol sorbitol-specific
JVX94_RS07070	COG2390	Transcriptional regulator
JVX94_RS07075	COG1191	sigma factor activity
JVX94_RS07080	COG1191	sigma factor activity
JVX94_RS07090	COG1404	Belongs to the peptidase S8 family
JVX94_RS07090	COG4412	M6 family metalloprotease domain protein
JVX94_RS07095	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JVX94_RS07100	COG0849	cell division
JVX94_RS07105	COG3856	small basic protein
JVX94_RS07110	COG3879	Bacterial protein of unknown function (DUF881)
JVX94_RS07115	COG3879	Bacterial protein of unknown function (DUF881)
JVX94_RS07120	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JVX94_RS07125	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JVX94_RS07130	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JVX94_RS07135	COG0772	Belongs to the SEDS family
JVX94_RS07140	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JVX94_RS07145	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JVX94_RS07150	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JVX94_RS07155	COG0768	penicillin binding
JVX94_RS07160	COG0768	penicillin binding
JVX94_RS07165	COG4839	cell division protein FtsL
JVX94_RS07170	COG0275	rRNA processing
JVX94_RS07175	COG2001	Belongs to the MraZ family
JVX94_RS07180	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
JVX94_RS07185	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JVX94_RS07190	COG0454	-acetyltransferase
JVX94_RS07200	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JVX94_RS07205	COG1399	metal-binding, possibly nucleic acid-binding protein
JVX94_RS07215	COG3480	Lon protease (S16) C-terminal proteolytic domain
JVX94_RS07220	COG1752	Esterase of the alpha-beta hydrolase superfamily
JVX94_RS07225	COG3314	Sporulation integral membrane protein YlbJ
JVX94_RS07230	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JVX94_RS07235	COG0742	ribosomal rna small subunit methyltransferase
JVX94_RS07240	COG4471	UPF0298 protein
JVX94_RS07245	COG3679	Belongs to the UPF0342 family
JVX94_RS07265	COG2340	Cysteine-rich secretory protein family
JVX94_RS07270	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
JVX94_RS07280	COG3336	cytochrome c oxidase
JVX94_RS07285	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JVX94_RS07290	COG1845	cytochrome c oxidase, subunit III
JVX94_RS07295	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JVX94_RS07300	COG2010	Cytochrome c
JVX94_RS07300	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JVX94_RS07305	COG0109	protoheme IX farnesyltransferase activity
JVX94_RS07310	COG1612	heme a metabolic process
JVX94_RS07315	COG0415	Belongs to the DNA photolyase family
JVX94_RS07320	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JVX94_RS07325	COG0772	Belongs to the SEDS family
JVX94_RS07330	COG4838	Belongs to the UPF0358 family
JVX94_RS07335	COG2066	Belongs to the glutaminase family
JVX94_RS07340	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JVX94_RS07345	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JVX94_RS07355	COG4896	Protein conserved in bacteria
JVX94_RS07365	COG1217	gtp-binding protein TYPA
JVX94_RS07385	COG1595	DNA-templated transcription, initiation
JVX94_RS07400	COG0483	inositol monophosphate 1-phosphatase activity
JVX94_RS07410	COG4493	Belongs to the UPF0637 family
JVX94_RS07415	COG4476	Belongs to the UPF0223 family
JVX94_RS07420	COG1982	Orn Lys Arg decarboxylase major
JVX94_RS07430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JVX94_RS07435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JVX94_RS07440	COG0508	dehydrogenase complex catalyzes the overall conversion of
JVX94_RS07445	COG0022	dehydrogenase e1 component
JVX94_RS07450	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JVX94_RS07465	COG0242	peptide deformylase activity
JVX94_RS07470	COG0561	phosphatase activity
JVX94_RS07475	COG5503	Protein of unknown function (DUF1447)
JVX94_RS07480	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JVX94_RS07485	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JVX94_RS07490	COG0569	domain protein
JVX94_RS07495	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
JVX94_RS07495	COG2105	PFAM AIG2 family protein
JVX94_RS07500	COG3852	Histidine kinase
JVX94_RS07505	COG2002	toxin-antitoxin pair type II binding
JVX94_RS07510	COG1077	Cell shape determining protein MreB Mrl
JVX94_RS07520	COG2309	aminopeptidase activity
JVX94_RS07525	COG0488	(ABC) transporter
JVX94_RS07535	COG0681	Belongs to the peptidase S26 family
JVX94_RS07540	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JVX94_RS07540	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JVX94_RS07540	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JVX94_RS07545	COG1105	Belongs to the carbohydrate kinase PfkB family
JVX94_RS07550	COG1349	DNA-binding transcription factor activity
JVX94_RS07555	COG0577	efflux transmembrane transporter activity
JVX94_RS07560	COG1136	(ABC) transporter
JVX94_RS07565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JVX94_RS07580	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
JVX94_RS07585	COG0314	molybdopterin synthase activity
JVX94_RS07590	COG1763	Mo-molybdopterin cofactor biosynthetic process
JVX94_RS07595	COG0303	'Molybdopterin
JVX94_RS07600	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JVX94_RS07605	COG0746	molybdenum cofactor guanylyltransferase activity
JVX94_RS07620	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JVX94_RS07625	COG0450	alkyl hydroperoxide reductase
JVX94_RS07630	COG0668	transmembrane transport
JVX94_RS07640	COG1473	amidohydrolase
JVX94_RS07645	COG2171	N-acyltransferase activity
JVX94_RS07650	COG0716	FMN binding
JVX94_RS07660	COG0716	FMN binding
JVX94_RS07665	COG0583	DNA-binding transcription factor activity
JVX94_RS07670	COG0517	IMP dehydrogenase activity
JVX94_RS07680	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
JVX94_RS07685	COG4703	Protein of unknown function (DUF1797)
JVX94_RS07690	COG3546	catalase activity
JVX94_RS07695	COG2200	EAL domain
JVX94_RS07700	COG1028	Short-chain dehydrogenase reductase Sdr
JVX94_RS07705	COG1408	metallophosphoesterase
JVX94_RS07710	COG1376	ErfK ybiS ycfS ynhG family protein
JVX94_RS07715	COG2814	Major facilitator Superfamily
JVX94_RS07725	COG0697	spore germination
JVX94_RS07730	COG2207	Transcriptional regulator
JVX94_RS07730	COG1917	Cupin 2, conserved barrel domain protein
JVX94_RS07745	COG0784	Response regulator, receiver
JVX94_RS07745	COG0835	chemotaxis
JVX94_RS07755	COG1714	RDD family
JVX94_RS07765	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JVX94_RS07770	COG0436	Aminotransferase
JVX94_RS07775	COG4191	Histidine kinase
JVX94_RS07780	COG0768	penicillin binding
JVX94_RS07785	COG2340	Cysteine-rich secretory protein family
JVX94_RS07790	COG2084	Dehydrogenase
JVX94_RS07800	COG0840	transmembrane signaling receptor activity
JVX94_RS07805	COG1533	DNA photolyase activity
JVX94_RS07815	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JVX94_RS07820	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JVX94_RS07825	COG2190	(PTS) system
JVX94_RS07825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JVX94_RS07825	COG1263	PTS System
JVX94_RS07830	COG3711	transcriptional antiterminator
JVX94_RS07835	COG1609	Transcriptional regulator
JVX94_RS07845	COG0006	proline dipeptidase activity
JVX94_RS07850	COG2217	Heavy metal translocating P-type atpase
JVX94_RS07855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JVX94_RS07860	COG2244	polysaccharide biosynthetic process
JVX94_RS07865	COG3773	Cell wall hydrolase
JVX94_RS07875	COG4873	Protein conserved in bacteria
JVX94_RS07880	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JVX94_RS07890	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JVX94_RS07895	COG0602	queuosine metabolic process
JVX94_RS07900	COG0720	synthase
JVX94_RS07905	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JVX94_RS07910	COG3949	Membrane
JVX94_RS07915	COG0542	response to heat
JVX94_RS07920	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JVX94_RS07925	COG1360	Flagellar Motor Protein
JVX94_RS07930	COG1846	Transcriptional regulator
JVX94_RS07935	COG3852	Histidine kinase
JVX94_RS07945	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
JVX94_RS07950	COG0235	Class ii aldolase
JVX94_RS07955	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
JVX94_RS07960	COG1850	ribulose-bisphosphate carboxylase activity
JVX94_RS07965	COG0436	Aminotransferase
JVX94_RS07970	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
JVX94_RS07975	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
JVX94_RS07985	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JVX94_RS07990	COG5002	protein histidine kinase activity
JVX94_RS07995	COG3594	Acyltransferase
JVX94_RS08010	COG2323	membrane
JVX94_RS08015	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JVX94_RS08020	COG0501	Belongs to the peptidase M48B family
JVX94_RS08040	COG1191	sigma factor activity
JVX94_RS08045	COG0861	Integral membrane protein TerC family
JVX94_RS08050	COG0586	Pfam SNARE associated Golgi protein
JVX94_RS08055	COG3300	MHYT domain
JVX94_RS08055	COG5001	Diguanylate cyclase
JVX94_RS08060	COG1846	Transcriptional regulator
JVX94_RS08075	COG0789	Transcriptional regulator
JVX94_RS08085	COG0583	DNA-binding transcription factor activity
JVX94_RS08095	COG2239	Acts as a magnesium transporter
JVX94_RS08105	COG3212	peptidase
JVX94_RS08110	COG3212	peptidase
JVX94_RS08115	COG5002	protein histidine kinase activity
JVX94_RS08115	COG3850	Histidine kinase
JVX94_RS08120	COG0745	RESPONSE REGULATOR receiver
JVX94_RS08135	COG1404	Belongs to the peptidase S8 family
JVX94_RS08140	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JVX94_RS08145	COG0590	tRNA wobble adenosine to inosine editing
JVX94_RS08150	COG1764	response to oxidative stress
JVX94_RS08155	COG1846	Transcriptional regulator
JVX94_RS08160	COG1764	response to oxidative stress
JVX94_RS08170	COG0457	Tetratricopeptide repeat
JVX94_RS08175	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JVX94_RS08180	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JVX94_RS08185	COG0788	formyltetrahydrofolate deformylase activity
JVX94_RS08195	COG2076	Multidrug Resistance protein
JVX94_RS08200	COG2076	Multidrug Resistance protein
JVX94_RS08215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JVX94_RS08230	COG1695	Transcriptional regulator
JVX94_RS08235	COG1607	acyl-coa hydrolase
JVX94_RS08240	COG1834	amidinotransferase
JVX94_RS08245	COG4608	Belongs to the ABC transporter superfamily
JVX94_RS08250	COG0791	NLP P60 protein
JVX94_RS08255	COG4948	Mandelate Racemase Muconate Lactonizing
JVX94_RS08260	COG1619	proteins homologs of microcin C7 resistance protein MccF
JVX94_RS08265	COG4166	transmembrane transport
JVX94_RS08270	COG0444	Belongs to the ABC transporter superfamily
JVX94_RS08275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JVX94_RS08280	COG0601	transmembrane transport
JVX94_RS08285	COG2362	D-Aminopeptidase
JVX94_RS08290	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JVX94_RS08295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JVX94_RS08300	COG0346	lactoylglutathione lyase activity
JVX94_RS08305	COG0531	amino acid
JVX94_RS08315	COG2390	Transcriptional regulator
JVX94_RS08320	COG1028	Short-chain dehydrogenase reductase Sdr
JVX94_RS08325	COG1028	Short-chain dehydrogenase reductase Sdr
JVX94_RS08330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JVX94_RS08335	COG0508	dehydrogenase complex catalyzes the overall conversion of
JVX94_RS08340	COG0022	dehydrogenase e1 component
JVX94_RS08340	COG0508	dehydrogenase complex catalyzes the overall conversion of
JVX94_RS08345	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JVX94_RS08350	COG1063	alcohol dehydrogenase
JVX94_RS08365	COG3775	system Galactitol-specific IIC component
JVX94_RS08375	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
JVX94_RS08380	COG4208	sulfate ABC transporter
JVX94_RS08390	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
JVX94_RS08395	COG0405	Gamma-glutamyltransferase
JVX94_RS08405	COG1392	Phosphate transport regulator
JVX94_RS08410	COG0306	phosphate transporter
JVX94_RS08430	COG5632	N-Acetylmuramoyl-L-alanine amidase
JVX94_RS08430	COG3409	Peptidoglycan-binding domain 1 protein
JVX94_RS08435	COG2856	Zn peptidase
JVX94_RS08440	COG4195	phage-related replication protein
JVX94_RS08455	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JVX94_RS08460	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JVX94_RS08465	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JVX94_RS08485	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JVX94_RS08535	COG2807	transmembrane transport
JVX94_RS08540	COG0583	DNA-binding transcription factor activity
JVX94_RS08560	COG0583	DNA-binding transcription factor activity
JVX94_RS08570	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
JVX94_RS08595	COG0457	Tetratricopeptide repeat
JVX94_RS08620	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JVX94_RS08630	COG0825	malonyl-CoA metabolic process
JVX94_RS08670	COG0626	cystathionine gamma-synthase activity
JVX94_RS08675	COG0626	cystathionine gamma-synthase activity
JVX94_RS08680	COG2382	esterase
JVX94_RS08685	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JVX94_RS08700	COG0210	DNA helicase
JVX94_RS08755	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JVX94_RS08760	COG0351	phosphomethylpyrimidine kinase
JVX94_RS08765	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JVX94_RS08770	COG2022	thiamine diphosphate biosynthetic process
JVX94_RS08775	COG2104	thiamine diphosphate biosynthetic process
JVX94_RS08785	COG0352	thiamine-phosphate diphosphorylase activity
JVX94_RS08790	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JVX94_RS08795	COG0569	domain protein
JVX94_RS08795	COG0475	glutathione-regulated potassium exporter activity
JVX94_RS08800	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JVX94_RS08805	COG0564	pseudouridine synthase activity
JVX94_RS08810	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JVX94_RS08815	COG2357	RelA SpoT domain protein
JVX94_RS08825	COG4116	CYTH
JVX94_RS08830	COG0741	lytic transglycosylase activity
JVX94_RS08845	COG2346	COG2346, Truncated hemoglobins
JVX94_RS08850	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JVX94_RS08860	COG1164	Oligoendopeptidase f
JVX94_RS08870	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JVX94_RS08875	COG4862	establishment of competence for transformation
JVX94_RS08880	COG0861	Integral membrane protein TerC family
JVX94_RS08885	COG1393	Belongs to the ArsC family
JVX94_RS08890	COG0456	acetyltransferase
JVX94_RS08900	COG4608	Belongs to the ABC transporter superfamily
JVX94_RS08905	COG0444	Belongs to the ABC transporter superfamily
JVX94_RS08910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JVX94_RS08915	COG0601	transmembrane transport
JVX94_RS08920	COG4166	transmembrane transport
JVX94_RS08925	COG0180	Tryptophanyl-tRNA synthetase
JVX94_RS08935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JVX94_RS08940	COG0601	transmembrane transport
JVX94_RS08950	COG4608	Belongs to the ABC transporter superfamily
JVX94_RS08955	COG0444	Belongs to the ABC transporter superfamily
JVX94_RS08960	COG5504	Zn-dependent protease
JVX94_RS08965	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JVX94_RS08970	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JVX94_RS08985	COG1744	ABC transporter substrate-binding protein PnrA-like
JVX94_RS08995	COG2267	carboxylic ester hydrolase activity
JVX94_RS09005	COG2814	Major facilitator Superfamily
JVX94_RS09015	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JVX94_RS09020	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JVX94_RS09025	COG0505	Belongs to the CarA family
JVX94_RS09030	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JVX94_RS09035	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JVX94_RS09040	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JVX94_RS09045	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JVX94_RS09050	COG2271	Major facilitator Superfamily
JVX94_RS09055	COG0277	FAD linked oxidase domain protein
JVX94_RS09060	COG2151	metal-sulfur cluster biosynthetic enzyme
JVX94_RS09065	COG1073	alpha beta
JVX94_RS09070	COG0561	phosphatase activity
JVX94_RS09090	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JVX94_RS09095	COG1307	EDD domain protein, DegV family
JVX94_RS09100	COG0840	transmembrane signaling receptor activity
JVX94_RS09105	COG1744	ABC transporter substrate-binding protein PnrA-like
JVX94_RS09110	COG2996	Protein conserved in bacteria
JVX94_RS09115	COG1666	GTP binding
JVX94_RS09120	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JVX94_RS09120	COG0646	methionine synthase
JVX94_RS09125	COG0646	methionine synthase
JVX94_RS09125	COG1410	methionine synthase
JVX94_RS09160	COG0076	glutamate decarboxylase activity
JVX94_RS09190	COG1917	Cupin 2, conserved barrel domain protein
JVX94_RS09190	COG2207	Transcriptional regulator
JVX94_RS09195	COG0534	Mate efflux family protein
JVX94_RS09200	COG1562	ergosterol biosynthetic process
JVX94_RS09215	COG0367	asparagine synthase
JVX94_RS09230	COG0179	Fumarylacetoacetate (FAA) hydrolase
JVX94_RS09240	COG5337	Spore coat protein CotH
JVX94_RS09280	COG1403	HNH endonuclease
JVX94_RS09285	COG0419	ATPase involved in DNA repair
JVX94_RS09290	COG0420	3'-5' exonuclease activity
JVX94_RS09295	COG1074	ATP-dependent DNA helicase activity
JVX94_RS09300	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
JVX94_RS09305	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
JVX94_RS09310	COG2259	Doxx family
JVX94_RS09315	COG0501	Belongs to the peptidase M48B family
JVX94_RS09325	COG3180	Ammonia monooxygenase
JVX94_RS09330	COG0681	Belongs to the peptidase S26 family
JVX94_RS09335	COG0398	Pfam SNARE associated Golgi protein
JVX94_RS09345	COG1316	TRANSCRIPTIONal
JVX94_RS09350	COG2732	(Barnase) inhibitor
JVX94_RS09355	COG2814	Major facilitator Superfamily
JVX94_RS09360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JVX94_RS09370	COG4903	ComK protein
JVX94_RS09380	COG1028	Short-chain dehydrogenase reductase Sdr
JVX94_RS09385	COG0723	plastoquinol--plastocyanin reductase activity
JVX94_RS09385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JVX94_RS09390	COG0840	transmembrane signaling receptor activity
JVX94_RS09395	COG0406	alpha-ribazole phosphatase activity
JVX94_RS09400	COG1404	Belongs to the peptidase S8 family
JVX94_RS09405	COG0501	Belongs to the peptidase M48B family
JVX94_RS09415	COG0318	PFAM AMP-dependent synthetase and ligase
JVX94_RS09420	COG0095	Lipoate-protein ligase
JVX94_RS09425	COG1234	tRNA 3'-trailer cleavage
JVX94_RS09435	COG1301	dicarboxylic acid transport
JVX94_RS09440	COG1363	Peptidase, m42
JVX94_RS09445	COG1511	domain protein
JVX94_RS09450	COG1309	transcriptional regulator
JVX94_RS09455	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JVX94_RS09460	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JVX94_RS09465	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JVX94_RS09470	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JVX94_RS09475	COG2329	Antibiotic biosynthesis monooxygenase
JVX94_RS09485	COG1473	amidohydrolase
JVX94_RS09495	COG4473	ABC transporter
JVX94_RS09500	COG1131	(ABC) transporter
JVX94_RS09505	COG0537	adenosine 5'-monophosphoramidase activity
JVX94_RS09510	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JVX94_RS09525	COG4980	gas vesicle protein
JVX94_RS09530	COG1846	Transcriptional regulator
JVX94_RS09555	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JVX94_RS09565	COG3481	metal-dependent phosphohydrolase, HD sub domain
JVX94_RS09570	COG4717	serine-type aminopeptidase activity
JVX94_RS09575	COG0420	3'-5' exonuclease activity
JVX94_RS09585	COG1024	Enoyl-CoA hydratase
JVX94_RS09595	COG0490	domain, Protein
JVX94_RS09600	COG0475	glutathione-regulated potassium exporter activity
JVX94_RS09610	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JVX94_RS09615	COG0561	phosphatase activity
JVX94_RS09620	COG3679	Belongs to the UPF0342 family
JVX94_RS09625	COG4399	Belongs to the UPF0754 family
JVX94_RS09630	COG0189	ligase activity
JVX94_RS09635	COG0189	ligase activity
JVX94_RS09645	COG2508	Transcriptional regulator
JVX94_RS09650	COG3842	ATPase activity
JVX94_RS09660	COG0702	epimerase
JVX94_RS09665	COG1132	(ABC) transporter
JVX94_RS09670	COG1132	(ABC) transporter
JVX94_RS09675	COG0589	response to stress
JVX94_RS09680	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JVX94_RS09685	COG0726	polysaccharide deacetylase
JVX94_RS09690	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JVX94_RS09695	COG0668	transmembrane transport
JVX94_RS09705	COG0584	glycerophosphoryl diester phosphodiesterase
JVX94_RS09710	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JVX94_RS09715	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JVX94_RS09725	COG1253	flavin adenine dinucleotide binding
JVX94_RS09730	COG0789	Transcriptional regulator
JVX94_RS09735	COG1253	flavin adenine dinucleotide binding
JVX94_RS09740	COG0204	Acyl-transferase
JVX94_RS09745	COG1595	DNA-templated transcription, initiation
JVX94_RS09760	COG0531	amino acid
JVX94_RS09765	COG0791	NLP P60 protein
JVX94_RS09765	COG1388	LysM domain
JVX94_RS09770	COG1785	Belongs to the alkaline phosphatase family
JVX94_RS09775	COG2719	SpoVR family
JVX94_RS09780	COG1017	nitric oxide dioxygenase activity
JVX94_RS09780	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JVX94_RS09785	COG1959	2 iron, 2 sulfur cluster binding
JVX94_RS09790	COG0753	catalase activity
JVX94_RS09810	COG2197	response regulator
JVX94_RS09815	COG2203	Gaf domain
JVX94_RS09815	COG4585	Histidine kinase
JVX94_RS09820	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JVX94_RS09825	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JVX94_RS09830	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JVX94_RS09835	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JVX94_RS09840	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
JVX94_RS09845	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JVX94_RS09850	COG3835	regulator
JVX94_RS09865	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JVX94_RS09865	COG3153	acetyltransferase
JVX94_RS09870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JVX94_RS09880	COG0564	pseudouridine synthase activity
JVX94_RS09885	COG3764	Sortase (surface protein transpeptidase)
JVX94_RS09890	COG0737	Belongs to the 5'-nucleotidase family
JVX94_RS09890	COG1525	nuclease
JVX94_RS09890	COG4085	toxin activity
JVX94_RS09895	COG5002	protein histidine kinase activity
JVX94_RS09900	COG5577	PFAM Coat F domain
JVX94_RS09925	COG3706	GGDEF domain
JVX94_RS09930	COG1278	Cold shock
JVX94_RS09940	COG0655	NAD(P)H dehydrogenase (quinone) activity
JVX94_RS09945	COG2814	Major facilitator Superfamily
JVX94_RS09950	COG1566	PFAM secretion protein HlyD family protein
JVX94_RS09955	COG2718	Belongs to the UPF0229 family
JVX94_RS09960	COG2766	serine protein kinase
JVX94_RS09965	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JVX94_RS09975	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JVX94_RS09980	COG3382	B3 4 domain protein
JVX94_RS10010	COG1131	(ABC) transporter
JVX94_RS10025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JVX94_RS10030	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JVX94_RS10035	COG1116	anion transmembrane transporter activity
JVX94_RS10045	COG2873	o-acetylhomoserine
JVX94_RS10050	COG0681	Belongs to the peptidase S26 family
JVX94_RS10055	COG1368	sulfuric ester hydrolase activity
JVX94_RS10255	COG0735	belongs to the Fur family
JVX94_RS10260	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JVX94_RS10265	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JVX94_RS10270	COG4129	membrane
JVX94_RS10275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JVX94_RS10280	COG0601	transmembrane transport
JVX94_RS10285	COG0747	negative chemotaxis
JVX94_RS10290	COG4608	Belongs to the ABC transporter superfamily
JVX94_RS10295	COG0444	Belongs to the ABC transporter superfamily
JVX94_RS10300	COG1132	(ABC) transporter
JVX94_RS10305	COG3557	Belongs to the UPF0374 family
JVX94_RS10320	COG1028	Short-chain dehydrogenase reductase Sdr
JVX94_RS10330	COG1194	a g-specific adenine glycosylase
JVX94_RS10335	COG1988	membrane-bound metal-dependent
JVX94_RS10380	COG1191	sigma factor activity
JVX94_RS10390	COG2140	Oxalate decarboxylase
JVX94_RS10405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JVX94_RS10410	COG4485	Bacterial membrane protein, YfhO
JVX94_RS10415	COG0463	Glycosyl transferase, family 2
JVX94_RS10440	COG2137	regulation of response to DNA damage stimulus
JVX94_RS10445	COG1090	epimerase
JVX94_RS10460	COG0778	Nitroreductase
JVX94_RS10480	COG0392	lysyltransferase activity
JVX94_RS10480	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JVX94_RS10485	COG1846	Transcriptional regulator
JVX94_RS10495	COG2318	DinB family
JVX94_RS10515	COG1595	DNA-templated transcription, initiation
JVX94_RS10520	COG1742	UPF0060 membrane protein
JVX94_RS10525	COG1132	(ABC) transporter
JVX94_RS10530	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JVX94_RS10535	COG2169	Transcriptional regulator
JVX94_RS10540	COG0492	ferredoxin-NADP+ reductase activity
JVX94_RS10545	COG2755	lipolytic protein G-D-S-L family
JVX94_RS10550	COG4637	Psort location Cytoplasmic, score
JVX94_RS10560	COG1309	transcriptional regulator
JVX94_RS10565	COG2076	Multidrug Resistance protein
JVX94_RS10570	COG2076	Multidrug Resistance protein
JVX94_RS10610	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JVX94_RS10620	COG2814	Major facilitator Superfamily
JVX94_RS10625	COG0789	Transcriptional regulator
JVX94_RS10630	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JVX94_RS10635	COG1942	4-Oxalocrotonate Tautomerase
JVX94_RS10640	COG0583	DNA-binding transcription factor activity
JVX94_RS10655	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JVX94_RS10660	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JVX94_RS10670	COG0598	Magnesium transport protein CorA
JVX94_RS10680	COG0726	polysaccharide deacetylase
JVX94_RS10690	COG0535	radical SAM domain protein
JVX94_RS10695	COG0668	transmembrane transport
JVX94_RS10700	COG0217	transcriptional regulatory protein
JVX94_RS10710	COG0387	Pfam Sodium calcium exchanger
JVX94_RS10720	COG0477	Major facilitator Superfamily
JVX94_RS10725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JVX94_RS10730	COG1295	ribonuclease BN
JVX94_RS10735	COG4980	gas vesicle protein
JVX94_RS10740	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JVX94_RS10745	COG1115	amino acid carrier protein
JVX94_RS10750	COG4840	Belongs to the UPF0435 family
JVX94_RS10755	COG0693	protein deglycase activity
JVX94_RS10760	COG0737	Belongs to the 5'-nucleotidase family
JVX94_RS10770	COG2188	Transcriptional regulator
JVX94_RS10775	COG0366	Alpha amylase catalytic
JVX94_RS10780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JVX94_RS10780	COG1263	PTS System
JVX94_RS10795	COG0076	glutamate decarboxylase activity
JVX94_RS10800	COG1368	sulfuric ester hydrolase activity
JVX94_RS10820	COG3739	integral membrane protein
JVX94_RS10825	COG1263	PTS System
JVX94_RS10825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JVX94_RS10830	COG0024	Methionine aminopeptidase
JVX94_RS10845	COG2258	MOSC domain
JVX94_RS10850	COG1254	Belongs to the acylphosphatase family
JVX94_RS10855	COG0583	DNA-binding transcription factor activity
JVX94_RS10860	COG0477	Major facilitator Superfamily
JVX94_RS10865	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
JVX94_RS10870	COG1695	Transcriptional regulator
JVX94_RS10875	COG3479	Phenolic acid decarboxylase
JVX94_RS10885	COG2851	Citrate transporter
JVX94_RS10890	COG3181	Tripartite tricarboxylate transporter family receptor
JVX94_RS10895	COG4565	transcriptional regulatory protein
JVX94_RS10900	COG3290	protein histidine kinase activity
JVX94_RS10910	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JVX94_RS10910	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JVX94_RS10920	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JVX94_RS10925	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JVX94_RS10925	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JVX94_RS10945	COG2130	NADP-dependent
JVX94_RS10950	COG0513	Belongs to the DEAD box helicase family
JVX94_RS10955	COG0488	(ABC) transporter
JVX94_RS10960	COG2814	Major facilitator Superfamily
JVX94_RS10965	COG0789	Transcriptional regulator
JVX94_RS10970	COG1469	GTP cyclohydrolase I activity
JVX94_RS10975	COG0488	(ABC) transporter
JVX94_RS10980	COG0463	Glycosyl transferase, family 2
JVX94_RS10985	COG0531	amino acid
JVX94_RS11000	COG0071	Belongs to the small heat shock protein (HSP20) family
JVX94_RS11015	COG0471	metal ion transport
JVX94_RS11025	COG2223	nitrite transmembrane transporter activity
JVX94_RS11030	COG1442	glycosyl transferase family 8
JVX94_RS11035	COG1216	Glycosyl transferase, family 2
JVX94_RS11040	COG1442	glycosyl transferase family 8
JVX94_RS11045	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JVX94_RS11050	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JVX94_RS11080	COG2211	Major facilitator Superfamily
JVX94_RS11090	COG1486	melibiose metabolic process
JVX94_RS11105	COG0492	ferredoxin-NADP+ reductase activity
JVX94_RS11110	COG1959	2 iron, 2 sulfur cluster binding
JVX94_RS11120	COG1486	melibiose metabolic process
JVX94_RS11125	COG1263	PTS System
JVX94_RS11125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JVX94_RS11130	COG1737	Transcriptional regulator
JVX94_RS11140	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JVX94_RS11145	COG0457	Tetratricopeptide repeat
JVX94_RS11165	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JVX94_RS11170	COG1597	lipid kinase activity
JVX94_RS11175	COG1957	nucleoside hydrolase
JVX94_RS11180	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JVX94_RS11185	COG1309	transcriptional regulator
JVX94_RS11190	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JVX94_RS11195	COG0154	amidase activity
JVX94_RS11200	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JVX94_RS11205	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JVX94_RS11210	COG1285	pathogenesis
JVX94_RS11215	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JVX94_RS11220	COG4851	CamS sex pheromone cAM373 precursor
JVX94_RS11225	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JVX94_RS11230	COG0210	DNA helicase
JVX94_RS11235	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
JVX94_RS11250	COG0069	glutamate synthase activity
JVX94_RS11260	COG4496	protein, YerC YecD
JVX94_RS11265	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JVX94_RS11275	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JVX94_RS11280	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JVX94_RS11285	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JVX94_RS11290	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JVX94_RS11310	COG0151	Belongs to the GarS family
JVX94_RS11315	COG0138	bifunctional purine biosynthesis protein purh
JVX94_RS11320	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JVX94_RS11325	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JVX94_RS11330	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JVX94_RS11335	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JVX94_RS11340	COG0047	phosphoribosylformylglycinamidine synthase activity
JVX94_RS11345	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JVX94_RS11350	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JVX94_RS11355	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JVX94_RS11360	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JVX94_RS11365	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JVX94_RS11375	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
JVX94_RS11380	COG3064	Membrane
JVX94_RS11395	COG2252	PERMEase
JVX94_RS11400	COG0583	DNA-binding transcription factor activity
JVX94_RS11405	COG2814	Major facilitator Superfamily
JVX94_RS11415	COG1595	DNA-templated transcription, initiation
JVX94_RS11450	COG2207	Transcriptional regulator
JVX94_RS11455	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JVX94_RS11460	COG1917	Cupin 2, conserved barrel domain protein
JVX94_RS11460	COG2207	Transcriptional regulator
JVX94_RS11465	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JVX94_RS11470	COG0519	Catalyzes the synthesis of GMP from XMP
JVX94_RS11470	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JVX94_RS11475	COG1305	Transglutaminase-like
JVX94_RS11480	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
JVX94_RS11485	COG0714	Associated with various cellular activities
JVX94_RS11490	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JVX94_RS11495	COG1113	amino acid transport
JVX94_RS11500	COG2132	Multicopper oxidase
JVX94_RS11510	COG0823	Involved in the tonB-independent uptake of proteins
JVX94_RS11515	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JVX94_RS11560	COG0459	protein refolding
JVX94_RS11565	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JVX94_RS11570	COG1266	CAAX protease self-immunity
JVX94_RS11585	COG0805	protein transport
JVX94_RS11590	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JVX94_RS11595	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JVX94_RS11600	COG0315	cyclic pyranopterin monophosphate synthase activity
JVX94_RS11605	COG0488	(ABC) transporter
JVX94_RS11610	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JVX94_RS11615	COG0456	acetyltransferase
JVX94_RS11620	COG1214	PFAM Peptidase M22, glycoprotease
JVX94_RS11625	COG0802	atpase or kinase
JVX94_RS11630	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
JVX94_RS11670	COG1301	dicarboxylic acid transport
JVX94_RS11680	COG0697	spore germination
JVX94_RS11685	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
JVX94_RS11695	COG4122	O-methyltransferase activity
JVX94_RS11705	COG0456	acetyltransferase
JVX94_RS11715	COG1396	sequence-specific DNA binding
JVX94_RS11730	COG0778	Nitroreductase
JVX94_RS11735	COG1846	Transcriptional regulator
JVX94_RS11740	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JVX94_RS11745	COG1309	transcriptional regulator
JVX94_RS11775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JVX94_RS11780	COG2814	Major facilitator Superfamily
JVX94_RS11800	COG0252	asparaginase activity
JVX94_RS11805	COG1404	Belongs to the peptidase S8 family
JVX94_RS11820	COG4221	oxidoreductase activity
JVX94_RS11830	COG0657	acetylesterase activity
JVX94_RS11835	COG0477	Major facilitator Superfamily
JVX94_RS11850	COG0789	Transcriptional regulator
JVX94_RS11855	COG1064	alcohol dehydrogenase
JVX94_RS11860	COG1329	Transcriptional regulator
JVX94_RS11865	COG1278	Cold shock
JVX94_RS11870	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JVX94_RS11870	COG0456	acetyltransferase
JVX94_RS11885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JVX94_RS11895	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JVX94_RS11905	COG2197	response regulator
JVX94_RS11910	COG4585	Histidine kinase
JVX94_RS11955	COG3284	Transcriptional regulator
JVX94_RS11960	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JVX94_RS11965	COG0508	dehydrogenase complex catalyzes the overall conversion of
JVX94_RS11970	COG0022	dehydrogenase e1 component
JVX94_RS11975	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JVX94_RS11980	COG3091	SprT-like family
JVX94_RS11990	COG2183	response to ionizing radiation
JVX94_RS11995	COG2208	phosphoserine phosphatase activity
JVX94_RS12000	COG1191	sigma factor activity
JVX94_RS12005	COG2172	sigma factor antagonist activity
JVX94_RS12010	COG1366	Belongs to the anti-sigma-factor antagonist family
JVX94_RS12015	COG2208	phosphoserine phosphatase activity
JVX94_RS12020	COG2172	sigma factor antagonist activity
JVX94_RS12025	COG1366	Belongs to the anti-sigma-factor antagonist family
JVX94_RS12030	COG1366	Belongs to the anti-sigma-factor antagonist family
JVX94_RS12035	COG2337	Toxic component of a toxin-antitoxin (TA) module
JVX94_RS12040	COG0864	Transcriptional regulator
JVX94_RS12045	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JVX94_RS12050	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
JVX94_RS12055	COG0736	holo-[acyl-carrier-protein] synthase activity
JVX94_RS12060	COG0705	Rhomboid family
JVX94_RS12065	COG3428	Bacterial PH domain
JVX94_RS12070	COG3402	PFAM membrane-flanked domain
JVX94_RS12075	COG0513	Belongs to the DEAD box helicase family
JVX94_RS12090	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JVX94_RS12095	COG1181	Belongs to the D-alanine--D-alanine ligase family
JVX94_RS12100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JVX94_RS12115	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
JVX94_RS12120	COG1131	(ABC) transporter
JVX94_RS12125	COG1301	dicarboxylic acid transport
JVX94_RS12130	COG0628	permease
JVX94_RS12135	COG1301	dicarboxylic acid transport
JVX94_RS12140	COG4565	transcriptional regulatory protein
JVX94_RS12145	COG3290	protein histidine kinase activity
JVX94_RS12150	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JVX94_RS12155	COG2217	Heavy metal translocating P-type atpase
JVX94_RS12160	COG2261	transglycosylase associated protein
JVX94_RS12165	COG1914	H( )-stimulated, divalent metal cation uptake system
JVX94_RS12170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JVX94_RS12205	COG0028	Belongs to the TPP enzyme family
JVX94_RS12210	COG0531	amino acid
JVX94_RS12220	COG1215	transferase activity, transferring glycosyl groups
JVX94_RS12225	COG5298	Protein conserved in bacteria
JVX94_RS12230	COG3706	GGDEF domain
JVX94_RS12235	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
JVX94_RS12240	COG0551	DNA topoisomerase type I activity
JVX94_RS12240	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JVX94_RS12245	COG0473	3-isopropylmalate dehydrogenase activity
JVX94_RS12250	COG0697	spore germination
JVX94_RS12255	COG1917	Cupin 2, conserved barrel domain protein
JVX94_RS12255	COG2207	Transcriptional regulator
JVX94_RS12260	COG1802	Transcriptional regulator
JVX94_RS12265	COG2814	Major facilitator Superfamily
JVX94_RS12290	COG3871	stress protein (general stress protein 26)
JVX94_RS12295	COG1028	Short-chain dehydrogenase reductase Sdr
JVX94_RS12300	COG2226	methyltransferase
JVX94_RS12305	COG3711	transcriptional antiterminator
JVX94_RS12315	COG2755	lipolytic protein G-D-S-L family
JVX94_RS12320	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JVX94_RS12325	COG1414	Transcriptional regulator
JVX94_RS12330	COG1984	allophanate hydrolase subunit 2
JVX94_RS12335	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JVX94_RS12340	COG4336	lyase activity
JVX94_RS12345	COG1914	H( )-stimulated, divalent metal cation uptake system
JVX94_RS12350	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JVX94_RS12355	COG0561	phosphatase activity
JVX94_RS12365	COG0346	lactoylglutathione lyase activity
JVX94_RS12385	COG4221	oxidoreductase activity
JVX94_RS12395	COG0840	transmembrane signaling receptor activity
JVX94_RS12400	COG0246	Mannitol dehydrogenase
JVX94_RS12405	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JVX94_RS12410	COG2213	PTS system mannitol-specific
JVX94_RS12415	COG1276	copper resistance
JVX94_RS12415	COG2372	response to copper ion
JVX94_RS12420	COG4549	nuclear export factor GLE1
JVX94_RS12425	COG2249	NAD(P)H dehydrogenase (quinone) activity
JVX94_RS12430	COG1012	belongs to the aldehyde dehydrogenase family
JVX94_RS12435	COG0531	amino acid
JVX94_RS12440	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JVX94_RS12445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JVX94_RS12450	COG0640	Transcriptional regulator
JVX94_RS12460	COG1309	transcriptional regulator
JVX94_RS12465	COG2814	Major facilitator Superfamily
JVX94_RS12470	COG0527	aspartate kinase activity
JVX94_RS12475	COG1366	Belongs to the anti-sigma-factor antagonist family
JVX94_RS12480	COG3850	Histidine kinase
JVX94_RS12480	COG5002	protein histidine kinase activity
JVX94_RS12485	COG0745	RESPONSE REGULATOR receiver
JVX94_RS12490	COG2079	MmgE PrpD family protein
JVX94_RS12495	COG1473	amidohydrolase
JVX94_RS12500	COG1126	abc transporter atp-binding protein
JVX94_RS12505	COG0765	amino acid transport
JVX94_RS12510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JVX94_RS12515	COG0456	acetyltransferase
JVX94_RS12520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JVX94_RS12525	COG5434	Belongs to the glycosyl hydrolase 28 family
JVX94_RS12530	COG3104	oligopeptide transport
JVX94_RS12535	COG0833	amino acid
JVX94_RS12540	COG0412	Dienelactone hydrolase
JVX94_RS12545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JVX94_RS12550	COG0765	amino acid transport
JVX94_RS12555	COG1126	abc transporter atp-binding protein
JVX94_RS12560	COG2002	toxin-antitoxin pair type II binding
JVX94_RS12565	COG3764	Sortase (surface protein transpeptidase)
JVX94_RS12575	COG2364	Membrane
JVX94_RS12585	COG2207	Transcriptional regulator
JVX94_RS12585	COG3708	Transcriptional regulator
JVX94_RS12595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JVX94_RS12600	COG0697	spore germination
JVX94_RS12605	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
JVX94_RS12620	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JVX94_RS12625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JVX94_RS12630	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JVX94_RS12645	COG3842	ATPase activity
JVX94_RS12665	COG3209	COG3209 Rhs family protein
JVX94_RS12670	COG0840	transmembrane signaling receptor activity
JVX94_RS12670	COG3290	protein histidine kinase activity
JVX94_RS12680	COG2746	aminoglycoside 3-N-acetyltransferase activity
JVX94_RS12685	COG1522	sequence-specific DNA binding
JVX94_RS12690	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JVX94_RS12700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JVX94_RS12705	COG0765	amino acid transport
JVX94_RS12710	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JVX94_RS12715	COG2508	Transcriptional regulator
JVX94_RS12720	COG1012	belongs to the aldehyde dehydrogenase family
JVX94_RS12725	COG0506	proline dehydrogenase activity
JVX94_RS12730	COG3541	Predicted nucleotidyltransferase
JVX94_RS12740	COG3458	cephalosporin-C deacetylase activity
JVX94_RS12745	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JVX94_RS12750	COG0583	DNA-binding transcription factor activity
JVX94_RS12755	COG2226	methyltransferase
JVX94_RS12760	COG0477	Major facilitator Superfamily
JVX94_RS12770	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JVX94_RS12775	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JVX94_RS12790	COG2271	Major facilitator Superfamily
JVX94_RS12795	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JVX94_RS12805	COG0028	Belongs to the TPP enzyme family
JVX94_RS12810	COG0710	3-dehydroquinate dehydratase activity
JVX94_RS12815	COG1012	belongs to the aldehyde dehydrogenase family
JVX94_RS12840	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JVX94_RS12845	COG3665	Urea carboxylase-associated protein
JVX94_RS12850	COG1113	amino acid transport
JVX94_RS12855	COG3403	YqcI/YcgG family
JVX94_RS12865	COG1280	lysine exporter protein (LysE YggA)
JVX94_RS12870	COG0738	Major facilitator superfamily
JVX94_RS12875	COG0673	inositol 2-dehydrogenase activity
JVX94_RS12880	COG0561	phosphatase activity
JVX94_RS12885	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JVX94_RS12890	COG1609	Transcriptional regulator
JVX94_RS12895	COG1620	l-lactate permease
JVX94_RS12900	COG0039	L-malate dehydrogenase activity
JVX94_RS12905	COG1288	antiporter activity
JVX94_RS12910	COG1473	amidohydrolase
JVX94_RS12925	COG2113	Glycine betaine
JVX94_RS12930	COG4176	ABC-type proline glycine betaine transport system permease component
JVX94_RS12935	COG0517	IMP dehydrogenase activity
JVX94_RS12935	COG4175	Glycine betaine
JVX94_RS12940	COG3853	Toxic anion resistance protein (TelA)
JVX94_RS12970	COG0861	Integral membrane protein TerC family
JVX94_RS12975	COG2310	stress, protein
JVX94_RS12980	COG2310	stress, protein
JVX94_RS12985	COG2310	stress, protein
JVX94_RS12990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JVX94_RS13000	COG1028	Short-chain dehydrogenase reductase Sdr
JVX94_RS13005	COG3773	Cell wall hydrolase
JVX94_RS13015	COG1404	Belongs to the peptidase S8 family
JVX94_RS13030	COG1668	transmembrane transport
JVX94_RS13035	COG4555	ABC transporter
JVX94_RS13040	COG3279	Response regulator of the LytR AlgR family
JVX94_RS13045	COG3290	protein histidine kinase activity
JVX94_RS13050	COG0667	Aldo Keto reductase
JVX94_RS13060	COG4585	Histidine kinase
JVX94_RS13065	COG2197	response regulator
JVX94_RS13075	COG3012	SEC-C Motif Domain Protein
JVX94_RS13075	COG1405	negative regulation of cell septum assembly
JVX94_RS13080	COG0784	Response regulator, receiver
JVX94_RS13085	COG4191	Histidine kinase
JVX94_RS13090	COG2066	Belongs to the glutaminase family
JVX94_RS13095	COG1115	amino acid carrier protein
JVX94_RS13100	COG0596	Alpha beta hydrolase
JVX94_RS13110	COG0531	amino acid
JVX94_RS13115	COG0318	PFAM AMP-dependent synthetase and ligase
JVX94_RS13120	COG1846	Transcriptional regulator
JVX94_RS13125	COG1063	alcohol dehydrogenase
JVX94_RS13130	COG1917	Cupin 2, conserved barrel domain protein
JVX94_RS13135	COG1309	transcriptional regulator
JVX94_RS13145	COG1404	Belongs to the peptidase S8 family
JVX94_RS13160	COG0456	acetyltransferase
JVX94_RS13165	COG2814	Major facilitator Superfamily
JVX94_RS13180	COG1695	Transcriptional regulator
JVX94_RS13185	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JVX94_RS13190	COG2040	homocysteine
JVX94_RS13195	COG0833	amino acid
JVX94_RS13215	COG1404	Belongs to the peptidase S8 family
JVX94_RS13225	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JVX94_RS13230	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JVX94_RS13235	COG0383	alpha-mannosidase activity
JVX94_RS13240	COG1940	carbohydrate kinase activity
JVX94_RS13245	COG3711	transcriptional antiterminator
JVX94_RS13245	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JVX94_RS13265	COG2723	6-phospho-beta-galactosidase activity
JVX94_RS13270	COG1263	PTS System
JVX94_RS13270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JVX94_RS13270	COG2190	(PTS) system
JVX94_RS13275	COG3711	transcriptional antiterminator
JVX94_RS13285	COG0531	amino acid
JVX94_RS13290	COG1054	Belongs to the UPF0176 family
JVX94_RS13295	COG0371	Dehydrogenase
JVX94_RS13300	COG0656	L-ascorbic acid biosynthetic process
JVX94_RS13310	COG1683	Conserved Protein
JVX94_RS13320	COG1846	Transcriptional regulator
JVX94_RS13330	COG2814	Major facilitator Superfamily
JVX94_RS13335	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JVX94_RS13345	COG0730	response to heat
JVX94_RS13350	COG0425	Belongs to the sulfur carrier protein TusA family
JVX94_RS13355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JVX94_RS13355	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JVX94_RS13360	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JVX94_RS13360	COG0425	Belongs to the sulfur carrier protein TusA family
JVX94_RS13370	COG2210	Belongs to the sulfur carrier protein TusA family
JVX94_RS13375	COG1937	Protein conserved in bacteria
JVX94_RS13400	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JVX94_RS13405	COG1331	Highly conserved protein containing a thioredoxin domain
JVX94_RS13410	COG1846	Transcriptional regulator
JVX94_RS13415	COG2153	protein acetylation
JVX94_RS13420	COG2364	Membrane
JVX94_RS13425	COG1331	Highly conserved protein containing a thioredoxin domain
JVX94_RS13430	COG1331	Highly conserved protein containing a thioredoxin domain
JVX94_RS13440	COG2271	Major facilitator Superfamily
JVX94_RS13445	COG0584	glycerophosphoryl diester phosphodiesterase
JVX94_RS13455	COG1113	amino acid transport
JVX94_RS13470	COG4555	ABC transporter
JVX94_RS13495	COG1309	transcriptional regulator
JVX94_RS13515	COG2311	Membrane
JVX94_RS13525	COG1413	lyase activity
JVX94_RS13535	COG1131	(ABC) transporter
JVX94_RS13550	COG1131	(ABC) transporter
JVX94_RS13580	COG1131	(ABC) transporter
JVX94_RS13585	COG2205	protein histidine kinase activity
JVX94_RS13590	COG0745	RESPONSE REGULATOR receiver
JVX94_RS13595	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JVX94_RS13600	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JVX94_RS13605	COG4856	YbbR-like protein
JVX94_RS13610	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JVX94_RS13615	COG5662	AntiSigma factor
JVX94_RS13620	COG1595	DNA-templated transcription, initiation
JVX94_RS13655	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JVX94_RS13660	COG1737	Transcriptional regulator
JVX94_RS13665	COG1263	PTS System
JVX94_RS13665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JVX94_RS13670	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JVX94_RS13675	COG1472	Belongs to the glycosyl hydrolase 3 family
JVX94_RS13680	COG3876	Protein conserved in bacteria
JVX94_RS13685	COG0385	Bile acid
JVX94_RS13715	COG0726	polysaccharide deacetylase
JVX94_RS13720	COG2194	sulfuric ester hydrolase activity
JVX94_RS13730	COG0489	protein tyrosine kinase activity
JVX94_RS13735	COG0860	N-Acetylmuramoyl-L-alanine amidase
JVX94_RS13760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JVX94_RS13770	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JVX94_RS13775	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JVX94_RS13780	COG0101	tRNA pseudouridine synthase activity
JVX94_RS13785	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JVX94_RS13790	COG1122	ATPase activity
JVX94_RS13795	COG1122	ATPase activity
JVX94_RS13800	COG0203	ribosomal protein L17
JVX94_RS13805	COG0202	RNA polymerase activity
JVX94_RS13810	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JVX94_RS13815	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JVX94_RS13820	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JVX94_RS13825	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JVX94_RS13830	COG0024	Methionine aminopeptidase
JVX94_RS13835	COG0563	adenylate kinase activity
JVX94_RS13840	COG0201	protein transport
JVX94_RS13845	COG0200	Binds to the 23S rRNA
JVX94_RS13850	COG1841	ribosomal large subunit assembly
JVX94_RS13855	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JVX94_RS13860	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JVX94_RS13865	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JVX94_RS13870	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JVX94_RS13875	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JVX94_RS13880	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JVX94_RS13885	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JVX94_RS13890	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JVX94_RS13895	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JVX94_RS13900	COG0255	Belongs to the universal ribosomal protein uL29 family
JVX94_RS13910	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JVX94_RS13915	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JVX94_RS13920	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JVX94_RS13925	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JVX94_RS13930	COG0089	rRNA binding
JVX94_RS13935	COG0088	Forms part of the polypeptide exit tunnel
JVX94_RS13940	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JVX94_RS13950	COG0596	Alpha beta hydrolase
JVX94_RS13955	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JVX94_RS13960	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JVX94_RS13965	COG0049	tRNA binding
JVX94_RS13970	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JVX94_RS13975	COG1358	cellular component organization or biogenesis
JVX94_RS13980	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JVX94_RS13985	COG0085	RNA polymerase activity
JVX94_RS13990	COG2813	Specifically methylates the guanine in position
JVX94_RS13995	COG0222	ribosome binding
JVX94_RS14000	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JVX94_RS14005	COG0081	regulation of translation
JVX94_RS14015	COG0250	Participates in transcription elongation, termination and antitermination
JVX94_RS14020	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JVX94_RS14025	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JVX94_RS14030	COG1595	DNA-templated transcription, initiation
JVX94_RS14035	COG3688	RNA-binding protein containing a PIN domain
JVX94_RS14040	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JVX94_RS14045	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JVX94_RS14050	COG0215	cysteine-tRNA ligase activity
JVX94_RS14055	COG1045	serine acetyltransferase
JVX94_RS14060	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JVX94_RS14065	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
JVX94_RS14070	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JVX94_RS14075	COG4956	integral membrane protein (PIN domain superfamily)
JVX94_RS14080	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
JVX94_RS14085	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JVX94_RS14090	COG0542	response to heat
JVX94_RS14095	COG3869	Catalyzes the specific phosphorylation of arginine residues in
JVX94_RS14100	COG3880	PFAM UvrB UvrC protein
JVX94_RS14105	COG4463	regulation of RNA biosynthetic process
JVX94_RS14185	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JVX94_RS14190	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JVX94_RS14195	COG1396	sequence-specific DNA binding
JVX94_RS14200	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JVX94_RS14205	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JVX94_RS14210	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JVX94_RS14215	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JVX94_RS14220	COG0512	Glutamine amidotransferase of anthranilate synthase
JVX94_RS14225	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JVX94_RS14230	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JVX94_RS14235	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JVX94_RS14240	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JVX94_RS14245	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
JVX94_RS14250	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JVX94_RS14255	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
JVX94_RS14260	COG0037	tRNA processing
JVX94_RS14265	COG0515	serine threonine protein kinase
JVX94_RS14270	COG2304	oxidoreductase activity
JVX94_RS14275	COG2208	phosphoserine phosphatase activity
JVX94_RS14290	COG1098	S1 RNA binding domain
JVX94_RS14295	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
JVX94_RS14310	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JVX94_RS14315	COG3956	TIGRFAM MazG family protein
JVX94_RS14320	COG2244	polysaccharide biosynthetic process
JVX94_RS14325	COG2002	toxin-antitoxin pair type II binding
JVX94_RS14330	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JVX94_RS14340	COG0193	aminoacyl-tRNA hydrolase activity
JVX94_RS14345	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JVX94_RS14350	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JVX94_RS14360	COG2088	sporulation resulting in formation of a cellular spore
JVX94_RS14365	COG0251	oxidation-reduction process
JVX94_RS14370	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JVX94_RS14375	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JVX94_RS14385	COG4466	Protein conserved in bacteria
JVX94_RS14395	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JVX94_RS14400	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JVX94_RS14405	COG3583	domain protein
JVX94_RS14405	COG3584	3D domain protein
JVX94_RS14410	COG0084	hydrolase, TatD family'
JVX94_RS14415	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JVX94_RS14415	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JVX94_RS14420	COG2002	toxin-antitoxin pair type II binding
JVX94_RS14425	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JVX94_RS14430	COG2827	Endonuclease containing a URI domain
JVX94_RS14435	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JVX94_RS14440	COG4467	Involved in initiation control of chromosome replication
JVX94_RS14445	COG1774	PSP1 C-terminal conserved region
JVX94_RS14450	COG0470	DNA polymerase III
JVX94_RS14455	COG1728	Protein conserved in bacteria
JVX94_RS14460	COG3870	Protein conserved in bacteria
JVX94_RS14465	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JVX94_RS14470	COG1982	Orn Lys Arg decarboxylase major
JVX94_RS14475	COG3853	Toxic anion resistance protein (TelA)
JVX94_RS14480	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
JVX94_RS14525	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JVX94_RS14530	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JVX94_RS14535	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JVX94_RS14545	COG0590	tRNA wobble adenosine to inosine editing
JVX94_RS14550	COG1335	isochorismatase
JVX94_RS14555	COG3858	chitin binding
JVX94_RS14555	COG1388	LysM domain
JVX94_RS14560	COG1428	Deoxynucleoside kinase
JVX94_RS14565	COG1428	Deoxynucleoside kinase
JVX94_RS14575	COG0840	transmembrane signaling receptor activity
JVX94_RS14580	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JVX94_RS14585	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
JVX94_RS14590	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
JVX94_RS14595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JVX94_RS14600	COG1686	Belongs to the peptidase S11 family
JVX94_RS14605	COG0517	IMP dehydrogenase activity
JVX94_RS14605	COG0516	GMP reductase activity
JVX94_RS14640	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JVX94_RS14645	COG0187	DNA topoisomerase II activity
JVX94_RS14655	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JVX94_RS14660	COG2501	S4 domain
JVX94_RS14665	COG0592	DNA-directed DNA polymerase activity
JVX94_RS14670	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JVX94_RS14675	COG0230	Belongs to the bacterial ribosomal protein bL34 family
JVX94_RS14680	COG0594	ribonuclease P activity
JVX94_RS14685	COG0706	membrane insertase activity
JVX94_RS14690	COG1847	R3H domain protein
JVX94_RS14695	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JVX94_RS14700	COG0445	tRNA wobble uridine modification
JVX94_RS14705	COG0357	Ribosomal RNA small subunit methyltransferase G
JVX94_RS14710	COG1475	DNA binding
JVX94_RS14715	COG1192	Involved in chromosome partitioning
JVX94_RS14720	COG1475	DNA binding
JVX94_RS14730	COG3949	Membrane
JVX94_RS14745	COG4481	Protein conserved in bacteria
JVX94_RS14750	COG0012	GTP binding
JVX94_RS14755	COG0360	Binds together with S18 to 16S ribosomal RNA
JVX94_RS14760	COG0629	single-stranded DNA binding
JVX94_RS14765	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JVX94_RS14770	COG0517	IMP dehydrogenase activity
JVX94_RS14770	COG1125	glycine betaine transport
JVX94_RS14775	COG1174	glycine betaine transport
JVX94_RS14780	COG0346	lactoylglutathione lyase activity
JVX94_RS14785	COG0400	carboxylic ester hydrolase activity
JVX94_RS14790	COG0655	NAD(P)H dehydrogenase (quinone) activity
JVX94_RS14795	COG0753	catalase activity
JVX94_RS14805	COG1595	DNA-templated transcription, initiation
JVX94_RS14815	COG1227	inorganic diphosphatase activity
JVX94_RS14820	COG4241	membrane
JVX94_RS14825	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
JVX94_RS14830	COG0359	binds to the 23S rRNA
JVX94_RS14835	COG2807	transmembrane transport
JVX94_RS14840	COG3093	addiction module antidote protein HigA
JVX94_RS14845	COG2819	hydrolase of the alpha beta superfamily
JVX94_RS14850	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JVX94_RS14855	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JVX94_RS14855	COG2207	Transcriptional regulator
JVX94_RS14860	COG3251	PFAM MbtH domain protein
JVX94_RS14865	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JVX94_RS14870	COG3433	isochorismatase activity
JVX94_RS14870	COG1535	isochorismatase
JVX94_RS14875	COG1021	2,3-dihydroxybenzoate-AMP ligase
JVX94_RS14880	COG1169	isochorismate synthase
JVX94_RS14885	COG1028	Short-chain dehydrogenase reductase Sdr
JVX94_RS14890	COG2819	hydrolase of the alpha beta superfamily
JVX94_RS14915	COG0305	Participates in initiation and elongation during chromosome replication
JVX94_RS14920	COG0346	lactoylglutathione lyase activity
JVX94_RS14925	COG2124	cytochrome p450
JVX94_RS14930	COG1309	transcriptional regulator
JVX94_RS14935	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JVX94_RS14940	COG2311	Membrane
JVX94_RS14950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JVX94_RS14975	COG0745	RESPONSE REGULATOR receiver
JVX94_RS14980	COG5002	protein histidine kinase activity
JVX94_RS14985	COG4863	YycH protein
JVX94_RS14990	COG4853	Protein conserved in bacteria
JVX94_RS14995	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JVX94_RS15000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JVX94_RS15005	COG0456	acetyltransferase
JVX94_RS15025	COG4720	Psort location CytoplasmicMembrane, score
JVX94_RS15035	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JVX94_RS15045	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JVX94_RS15050	COG2815	serine threonine protein kinase
JVX94_RS15050	COG0515	serine threonine protein kinase
JVX94_RS15075	COG0640	Transcriptional regulator
JVX94_RS15080	COG2814	Major facilitator Superfamily
JVX94_RS15105	COG0583	DNA-binding transcription factor activity
JVX94_RS15110	COG0384	phenazine biosynthesis protein PhzF
JVX94_RS15125	COG2188	Transcriptional regulator
JVX94_RS15135	COG2723	6-phospho-beta-galactosidase activity
JVX94_RS15155	COG1263	PTS System
JVX94_RS15155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JVX94_RS15155	COG2190	(PTS) system
JVX94_RS15165	COG2723	6-phospho-beta-galactosidase activity
JVX94_RS15170	COG2814	Major facilitator Superfamily
JVX94_RS15180	COG2814	Major facilitator Superfamily
JVX94_RS15185	COG1609	Transcriptional regulator
JVX94_RS15190	COG1113	amino acid transport
JVX94_RS15225	COG2190	(PTS) system
JVX94_RS15225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JVX94_RS15225	COG1263	PTS System
JVX94_RS15230	COG2723	6-phospho-beta-galactosidase activity
JVX94_RS15235	COG3711	transcriptional antiterminator
JVX94_RS15240	COG0457	Tetratricopeptide repeat
JVX94_RS15250	COG0577	efflux transmembrane transporter activity
JVX94_RS15250	COG1136	(ABC) transporter
JVX94_RS15260	COG2814	Major facilitator Superfamily
JVX94_RS15265	COG1309	transcriptional regulator
JVX94_RS15270	COG3835	regulator
JVX94_RS15275	COG2610	gluconate transmembrane transporter activity
JVX94_RS15280	COG1929	Belongs to the glycerate kinase type-1 family
JVX94_RS15285	COG2824	Alkylphosphonate utilization operon protein PhnA
JVX94_RS15290	COG1131	(ABC) transporter
JVX94_RS15295	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
JVX94_RS15305	COG2851	Citrate transporter
JVX94_RS15310	COG1874	Beta-galactosidase
JVX94_RS15320	COG3833	ABC-type maltose transport systems, permease component
JVX94_RS15325	COG1175	transmembrane transport
JVX94_RS15330	COG2182	Extracellular solute-binding protein
JVX94_RS15335	COG1609	Transcriptional regulator
JVX94_RS15340	COG0583	DNA-binding transcription factor activity
JVX94_RS15375	COG1737	Transcriptional regulator
JVX94_RS15380	COG1070	Carbohydrate kinase
JVX94_RS15390	COG4335	DNA alkylation repair
JVX94_RS15395	COG1113	amino acid transport
JVX94_RS15400	COG0840	transmembrane signaling receptor activity
JVX94_RS15405	COG0673	inositol 2-dehydrogenase activity
JVX94_RS15410	COG0789	Transcriptional regulator
JVX94_RS15415	COG0561	phosphatase activity
JVX94_RS15435	COG2755	lipolytic protein G-D-S-L family
JVX94_RS15435	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JVX94_RS15445	COG2390	Transcriptional regulator
JVX94_RS15450	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JVX94_RS15455	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JVX94_RS15460	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
JVX94_RS15465	COG1846	Transcriptional regulator
JVX94_RS15470	COG0778	Nitroreductase
JVX94_RS15475	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
JVX94_RS15510	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JVX94_RS15515	COG4721	ABC-type cobalt transport system, permease component
JVX94_RS15520	COG1122	ATPase activity
JVX94_RS15525	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JVX94_RS15535	COG3878	Protein conserved in bacteria
JVX94_RS15540	COG3711	transcriptional antiterminator
JVX94_RS15545	COG2190	(PTS) system
JVX94_RS15545	COG1263	PTS System
JVX94_RS15545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JVX94_RS15550	COG2723	6-phospho-beta-galactosidase activity
JVX94_RS15555	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JVX94_RS15560	COG2610	gluconate transmembrane transporter activity
JVX94_RS15570	COG2084	Dehydrogenase
JVX94_RS15575	COG1737	Transcriptional regulator
JVX94_RS15590	COG2195	Cleaves the N-terminal amino acid of tripeptides
JVX94_RS15595	COG4842	Belongs to the WXG100 family
JVX94_RS15620	COG1396	sequence-specific DNA binding
JVX94_RS15625	COG0252	asparaginase activity
JVX94_RS15630	COG1027	Aspartate ammonia-lyase
JVX94_RS15635	COG1757	Na H antiporter
JVX94_RS15660	COG3711	transcriptional antiterminator
JVX94_RS15660	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JVX94_RS15665	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JVX94_RS15670	COG2723	6-phospho-beta-galactosidase activity
JVX94_RS15675	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JVX94_RS15680	COG1447	Phosphotransferase system cellobiose-specific component IIA
JVX94_RS15685	COG0726	polysaccharide deacetylase
JVX94_RS15695	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JVX94_RS15695	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JVX94_RS15700	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JVX94_RS15700	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JVX94_RS15705	COG2514	catechol 2,3-dioxygenase activity
JVX94_RS15710	COG1733	regulation of RNA biosynthetic process
JVX94_RS15715	COG5386	Cell surface protein
JVX94_RS15720	COG5386	Cell surface protein
JVX94_RS15745	COG4509	Sortase family
JVX94_RS15755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JVX94_RS15765	COG1271	oxidase subunit
JVX94_RS15770	COG1294	oxidase, subunit
JVX94_RS15775	COG4988	ABC transporter
JVX94_RS15780	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JVX94_RS15790	COG1595	DNA-templated transcription, initiation
JVX94_RS15805	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JVX94_RS15820	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JVX94_RS15820	COG3711	transcriptional antiterminator
JVX94_RS15825	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JVX94_RS15830	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JVX94_RS15835	COG1447	Phosphotransferase system cellobiose-specific component IIA
JVX94_RS15840	COG1486	melibiose metabolic process
JVX94_RS15850	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JVX94_RS15855	COG3420	alginic acid biosynthetic process
JVX94_RS15865	COG1129	ABC transporter
JVX94_RS15870	COG1172	Belongs to the binding-protein-dependent transport system permease family
JVX94_RS15875	COG2357	RelA SpoT domain protein
JVX94_RS15885	COG0457	Tetratricopeptide repeat
JVX94_RS15890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JVX94_RS15895	COG0765	amino acid transport
JVX94_RS15905	COG0346	lactoylglutathione lyase activity
JVX94_RS15910	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JVX94_RS15915	COG1346	cytolysis
JVX94_RS15920	COG1380	Effector of murein hydrolase LrgA
JVX94_RS15925	COG0583	DNA-binding transcription factor activity
JVX94_RS15930	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JVX94_RS15935	COG0352	thiamine-phosphate diphosphorylase activity
JVX94_RS15950	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JVX94_RS15955	COG3162	membrane
JVX94_RS15975	COG2246	polysaccharide biosynthetic process
JVX94_RS15990	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JVX94_RS15995	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JVX94_RS16000	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
JVX94_RS16010	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JVX94_RS16015	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JVX94_RS16020	COG1845	cytochrome c oxidase, subunit III
JVX94_RS16025	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JVX94_RS16035	COG0772	Belongs to the SEDS family
JVX94_RS16040	COG0778	Nitroreductase
JVX94_RS16045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JVX94_RS16050	COG1404	Belongs to the peptidase S8 family
JVX94_RS16060	COG3711	transcriptional antiterminator
JVX94_RS16065	COG1263	PTS System
JVX94_RS16065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JVX94_RS16070	COG1621	beta-fructofuranosidase activity
JVX94_RS16080	COG3964	amidohydrolase
JVX94_RS16100	COG0351	phosphomethylpyrimidine kinase
JVX94_RS16110	COG1216	Glycosyl transferase, family 2
JVX94_RS16115	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JVX94_RS16120	COG1012	belongs to the aldehyde dehydrogenase family
JVX94_RS16130	COG2233	PERMEase
JVX94_RS16135	COG2363	Small membrane protein
JVX94_RS16155	COG0463	Glycosyl transferase, family 2
JVX94_RS16160	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JVX94_RS16165	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JVX94_RS16170	COG0456	acetyltransferase
JVX94_RS16175	COG2089	acid synthase
JVX94_RS16180	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
JVX94_RS16185	COG3980	spore coat polysaccharide biosynthesis protein
JVX94_RS16190	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JVX94_RS16195	COG1088	dTDP-glucose 4,6-dehydratase activity
JVX94_RS16200	COG1091	dTDP-4-dehydrorhamnose reductase activity
JVX94_RS16205	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
JVX94_RS16210	COG1028	Short-chain dehydrogenase reductase Sdr
JVX94_RS16215	COG0436	Aminotransferase
JVX94_RS16220	COG0151	Belongs to the GarS family
JVX94_RS16225	COG1028	Short-chain dehydrogenase reductase Sdr
JVX94_RS16235	COG0077	Prephenate dehydratase
JVX94_RS16240	COG2814	Major facilitator Superfamily
JVX94_RS16245	COG1522	sequence-specific DNA binding
JVX94_RS16260	COG0280	phosphate acetyltransferase
JVX94_RS16270	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JVX94_RS16300	COG5444	nuclease activity
JVX94_RS16350	COG4844	belongs to the
JVX94_RS16355	COG1078	dGTPase activity
JVX94_RS16360	COG3465	dGTPase activity
JVX94_RS16370	COG1942	4-Oxalocrotonate Tautomerase
JVX94_RS16375	COG1994	Peptidase M50
JVX94_RS16385	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JVX94_RS16390	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JVX94_RS16395	COG0010	Belongs to the arginase family
JVX94_RS16405	COG4506	Protein conserved in bacteria
JVX94_RS16410	COG0018	arginyl-trna synthetase
JVX94_RS16425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JVX94_RS16430	COG1132	(ABC) transporter
JVX94_RS16435	COG1619	proteins homologs of microcin C7 resistance protein MccF
JVX94_RS16445	COG4294	response to UV
JVX94_RS16450	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JVX94_RS16455	COG2181	nitrate reductase activity
JVX94_RS16455	COG0247	lactate metabolic process
JVX94_RS16460	COG0183	Belongs to the thiolase family
JVX94_RS16465	COG1250	3-hydroxyacyl-CoA dehydrogenase
JVX94_RS16470	COG1960	acyl-CoA dehydrogenase activity
JVX94_RS16475	COG1960	acyl-CoA dehydrogenase activity
JVX94_RS16485	COG3343	RNA polymerase activity
JVX94_RS16490	COG0504	CTP synthase activity
JVX94_RS16495	COG4821	SIS domain
JVX94_RS16500	COG2204	response regulator
JVX94_RS16505	COG0191	fructose-bisphosphate aldolase activity
JVX94_RS16510	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JVX94_RS16515	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JVX94_RS16520	COG1494	fructose-1,6-bisphosphatase
JVX94_RS16525	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JVX94_RS16530	COG0254	rRNA binding
JVX94_RS16535	COG1435	thymidine kinase activity
JVX94_RS16540	COG0281	malic enzyme
JVX94_RS16545	COG0679	Auxin Efflux Carrier
JVX94_RS16550	COG0789	Transcriptional regulator
JVX94_RS16555	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JVX94_RS16560	COG2890	protein-(glutamine-N5) methyltransferase activity
JVX94_RS16575	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
JVX94_RS16580	COG0009	L-threonylcarbamoyladenylate synthase
JVX94_RS16585	COG1971	Probably functions as a manganese efflux pump
JVX94_RS16590	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JVX94_RS16595	COG0698	ribose 5-phosphate isomerase
JVX94_RS16600	COG4475	Protein of unknown function (DUF436)
JVX94_RS16605	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JVX94_RS16610	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JVX94_RS16620	COG0356	it plays a direct role in the translocation of protons across the membrane
JVX94_RS16625	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JVX94_RS16630	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JVX94_RS16635	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JVX94_RS16640	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JVX94_RS16645	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JVX94_RS16650	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JVX94_RS16655	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JVX94_RS16665	COG4836	Membrane
JVX94_RS16675	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JVX94_RS16680	COG2385	sporulation resulting in formation of a cellular spore
JVX94_RS16685	COG2304	oxidoreductase activity
JVX94_RS16690	COG2304	oxidoreductase activity
JVX94_RS16695	COG0243	molybdopterin cofactor binding
JVX94_RS16700	COG2223	nitrite transmembrane transporter activity
JVX94_RS16705	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JVX94_RS16710	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JVX94_RS16715	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JVX94_RS16720	COG0523	cobalamin synthesis protein
JVX94_RS16725	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JVX94_RS16765	COG1247	-acetyltransferase
JVX94_RS16770	COG0739	heme binding
JVX94_RS16775	COG0347	Belongs to the P(II) protein family
JVX94_RS16780	COG0004	ammonium transporteR
JVX94_RS16785	COG1126	abc transporter atp-binding protein
JVX94_RS16790	COG0765	amino acid transport
JVX94_RS16795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JVX94_RS16800	COG0477	Major facilitator Superfamily
JVX94_RS16805	COG0671	phosphoesterase, PA-phosphatase related
JVX94_RS16810	COG2814	Major facilitator Superfamily
JVX94_RS16815	COG1846	Transcriptional regulator
JVX94_RS16820	COG1609	Transcriptional regulator
JVX94_RS16825	COG1077	Cell shape determining protein MreB Mrl
JVX94_RS16830	COG4786	Flagellar basal body rod
JVX94_RS16835	COG4786	Flagellar basal body rod
JVX94_RS16840	COG0457	Tetratricopeptide repeat
JVX94_RS16845	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JVX94_RS16850	COG1970	mechanosensitive ion channel activity
JVX94_RS16865	COG0561	phosphatase activity
JVX94_RS16870	COG2202	Pas domain
JVX94_RS16870	COG1366	Belongs to the anti-sigma-factor antagonist family
JVX94_RS16875	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JVX94_RS16880	COG4715	Zinc finger, swim domain protein
JVX94_RS16890	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JVX94_RS16895	COG2059	Chromate
JVX94_RS16900	COG2059	Chromate
JVX94_RS16905	COG1522	sequence-specific DNA binding
JVX94_RS16910	COG3527	Alpha-acetolactate decarboxylase
JVX94_RS16915	COG0028	Belongs to the TPP enzyme family
JVX94_RS16920	COG0583	DNA-binding transcription factor activity
JVX94_RS16925	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JVX94_RS16930	COG1879	ABC-type sugar transport system periplasmic component
JVX94_RS16935	COG1172	Belongs to the binding-protein-dependent transport system permease family
JVX94_RS16940	COG1129	ABC transporter
JVX94_RS16945	COG1869	D-ribose catabolic process
JVX94_RS16950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JVX94_RS16955	COG1609	Transcriptional regulator
JVX94_RS16970	COG0697	spore germination
JVX94_RS16975	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JVX94_RS16985	COG2843	Capsule synthesis protein
JVX94_RS16995	COG0791	NLP P60 protein
JVX94_RS17000	COG0561	phosphatase activity
JVX94_RS17005	COG1316	TRANSCRIPTIONal
JVX94_RS17010	COG2814	Major facilitator Superfamily
JVX94_RS17025	COG0814	amino acid
JVX94_RS17030	COG0697	spore germination
JVX94_RS17035	COG1028	Short-chain dehydrogenase reductase Sdr
JVX94_RS17040	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
JVX94_RS17045	COG1609	Transcriptional regulator
JVX94_RS17050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JVX94_RS17055	COG0800	Aldolase
JVX94_RS17060	COG0454	-acetyltransferase
JVX94_RS17070	COG2972	Histidine kinase
JVX94_RS17075	COG2197	response regulator
JVX94_RS17080	COG1653	transport
JVX94_RS17085	COG1175	transmembrane transport
JVX94_RS17095	COG1482	cell wall glycoprotein biosynthetic process
JVX94_RS17100	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JVX94_RS17100	COG0463	Glycosyl transferase, family 2
JVX94_RS17105	COG4193	domain, Protein
JVX94_RS17110	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JVX94_RS17115	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
JVX94_RS17120	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JVX94_RS17130	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JVX94_RS17135	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JVX94_RS17145	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JVX94_RS17150	COG1181	Belongs to the D-alanine--D-alanine ligase family
JVX94_RS17160	COG1216	Glycosyl transferase, family 2
JVX94_RS17165	COG1682	transport, permease protein
JVX94_RS17170	COG1134	teichoic acid transport
JVX94_RS17175	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JVX94_RS17180	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JVX94_RS17185	COG1316	TRANSCRIPTIONal
JVX94_RS17195	COG2385	sporulation resulting in formation of a cellular spore
JVX94_RS17195	COG2247	cell wall binding repeat
JVX94_RS17200	COG2247	cell wall binding repeat
JVX94_RS17200	COG0860	N-Acetylmuramoyl-L-alanine amidase
JVX94_RS17205	COG2247	cell wall binding repeat
JVX94_RS17205	COG0860	N-Acetylmuramoyl-L-alanine amidase
JVX94_RS17220	COG2244	polysaccharide biosynthetic process
JVX94_RS17225	COG0297	glycogen (starch) synthase activity
JVX94_RS17225	COG0438	transferase activity, transferring glycosyl groups
JVX94_RS17230	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JVX94_RS17235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JVX94_RS17240	COG3307	-O-antigen
JVX94_RS17245	COG3206	protein involved in exopolysaccharide biosynthesis
JVX94_RS17250	COG1215	transferase activity, transferring glycosyl groups
JVX94_RS17255	COG0438	transferase activity, transferring glycosyl groups
JVX94_RS17260	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JVX94_RS17265	COG1316	TRANSCRIPTIONal
JVX94_RS17270	COG1739	Uncharacterized protein family UPF0029
JVX94_RS17275	COG4585	Histidine kinase
JVX94_RS17280	COG2197	response regulator
JVX94_RS17285	COG1307	EDD domain protein, DegV family
JVX94_RS17290	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JVX94_RS17300	COG1040	competence protein
JVX94_RS17315	COG3418	PFAM FlgN family protein
JVX94_RS17320	COG4786	Flagellar basal body rod
JVX94_RS17320	COG1256	bacterial-type flagellum assembly
JVX94_RS17325	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JVX94_RS17335	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
JVX94_RS17340	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
JVX94_RS17345	COG1334	flagellar protein FlaG
JVX94_RS17350	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
JVX94_RS17355	COG1516	flagellar protein fliS
JVX94_RS17370	COG0840	transmembrane signaling receptor activity
JVX94_RS17375	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JVX94_RS17380	COG0653	protein targeting
JVX94_RS17400	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JVX94_RS17405	COG2010	Cytochrome c
JVX94_RS17410	COG2884	Cell division ATP-binding protein ftsE
JVX94_RS17415	COG2177	Part of the ABC transporter FtsEX involved in
JVX94_RS17420	COG0791	NLP P60 protein
JVX94_RS17420	COG3883	PFAM NLP P60 protein
JVX94_RS17425	COG0730	response to heat
JVX94_RS17430	COG0793	Belongs to the peptidase S41A family
JVX94_RS17430	COG3409	Peptidoglycan-binding domain 1 protein
JVX94_RS17440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JVX94_RS17445	COG1733	regulation of RNA biosynthetic process
JVX94_RS17450	COG0778	Nitroreductase
JVX94_RS17455	COG1113	amino acid transport
JVX94_RS17460	COG0463	Glycosyl transferase, family 2
JVX94_RS17465	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JVX94_RS17470	COG5002	protein histidine kinase activity
JVX94_RS17475	COG0745	RESPONSE REGULATOR receiver
JVX94_RS17485	COG2814	Major facilitator Superfamily
JVX94_RS17490	COG1309	transcriptional regulator
JVX94_RS17495	COG0574	Belongs to the PEP-utilizing enzyme family
JVX94_RS17495	COG3848	Pyruvate phosphate dikinase
JVX94_RS17500	COG4897	Protein conserved in bacteria
JVX94_RS17510	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JVX94_RS17525	COG3595	metallopeptidase activity
JVX94_RS17530	COG1983	PspC domain protein
JVX94_RS17535	COG1950	PFAM Membrane protein of
JVX94_RS17540	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JVX94_RS17545	COG2188	Transcriptional regulator
JVX94_RS17550	COG0363	glucosamine-6-phosphate deaminase activity
JVX94_RS17555	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JVX94_RS17560	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JVX94_RS17565	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JVX94_RS17570	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
JVX94_RS17575	COG0546	phosphoglycolate phosphatase activity
JVX94_RS17580	COG0110	maltose O-acetyltransferase activity
JVX94_RS17585	COG1959	2 iron, 2 sulfur cluster binding
JVX94_RS17590	COG2910	NAD(P)H-binding
JVX94_RS17600	COG4990	cell redox homeostasis
JVX94_RS17605	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
JVX94_RS17610	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JVX94_RS17615	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JVX94_RS17620	COG0131	Imidazoleglycerol-phosphate dehydratase
JVX94_RS17625	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JVX94_RS17630	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JVX94_RS17635	COG0107	imidazoleglycerol-phosphate synthase activity
JVX94_RS17640	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JVX94_RS17640	COG0140	phosphoribosyl-ATP diphosphatase activity
JVX94_RS17645	COG0457	Tetratricopeptide repeat
JVX94_RS17650	COG0791	NLP P60 protein
JVX94_RS17650	COG3883	PFAM NLP P60 protein
JVX94_RS17655	COG0492	ferredoxin-NADP+ reductase activity
JVX94_RS17660	COG1051	belongs to the nudix hydrolase family
JVX94_RS17665	COG1660	Displays ATPase and GTPase activities
JVX94_RS17670	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JVX94_RS17675	COG1481	regulation of sporulation
JVX94_RS17680	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JVX94_RS17685	COG2162	N-hydroxyarylamine O-acetyltransferase activity
JVX94_RS17695	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JVX94_RS17700	COG0288	reversible hydration of carbon dioxide
JVX94_RS17705	COG0659	secondary active sulfate transmembrane transporter activity
JVX94_RS17710	COG1694	Mazg nucleotide pyrophosphohydrolase
JVX94_RS17715	COG1611	Belongs to the LOG family
JVX94_RS17720	COG0740	serine-type endopeptidase activity
JVX94_RS17745	COG1819	glycosyl
JVX94_RS17755	COG0488	(ABC) transporter
JVX94_RS17760	COG0726	polysaccharide deacetylase
JVX94_RS17765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JVX94_RS17770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JVX94_RS17775	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JVX94_RS17785	COG1396	sequence-specific DNA binding
JVX94_RS17790	COG3944	biosynthesis protein
JVX94_RS17795	COG0489	protein tyrosine kinase activity
JVX94_RS17800	COG1086	Polysaccharide biosynthesis protein
JVX94_RS17805	COG0438	transferase activity, transferring glycosyl groups
JVX94_RS17810	COG1215	transferase activity, transferring glycosyl groups
JVX94_RS17815	COG0438	transferase activity, transferring glycosyl groups
JVX94_RS17825	COG1216	Glycosyl transferase, family 2
JVX94_RS17830	COG5039	Polysaccharide pyruvyl transferase
JVX94_RS17835	COG2244	polysaccharide biosynthetic process
JVX94_RS17840	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JVX94_RS17845	COG0110	maltose O-acetyltransferase activity
JVX94_RS17850	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JVX94_RS17855	COG0747	negative chemotaxis
JVX94_RS17860	COG0601	transmembrane transport
JVX94_RS17865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JVX94_RS17870	COG0444	Belongs to the ABC transporter superfamily
JVX94_RS17875	COG4608	Belongs to the ABC transporter superfamily
JVX94_RS17880	COG0534	Mate efflux family protein
JVX94_RS17890	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
JVX94_RS17895	COG2186	Transcriptional regulator
JVX94_RS17900	COG3829	transcription factor binding
JVX94_RS17905	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JVX94_RS17910	COG0833	amino acid
JVX94_RS17915	COG2390	Transcriptional regulator
JVX94_RS17920	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JVX94_RS17925	COG0126	phosphoglycerate kinase activity
JVX94_RS17930	COG0149	triose-phosphate isomerase activity
JVX94_RS17935	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JVX94_RS17940	COG0148	phosphopyruvate hydratase activity
JVX94_RS17970	COG0456	acetyltransferase
JVX94_RS17980	COG2095	MarC family integral membrane protein
JVX94_RS17985	COG1510	regulation of RNA biosynthetic process
JVX94_RS17990	COG0517	IMP dehydrogenase activity
JVX94_RS17990	COG1125	glycine betaine transport
JVX94_RS17995	COG1174	glycine betaine transport
JVX94_RS18000	COG1732	Glycine betaine
JVX94_RS18005	COG1174	glycine betaine transport
JVX94_RS18010	COG1733	regulation of RNA biosynthetic process
JVX94_RS18015	COG1396	sequence-specific DNA binding
JVX94_RS18020	COG1396	sequence-specific DNA binding
JVX94_RS18025	COG1476	TRANSCRIPTIONal
JVX94_RS18030	COG2002	toxin-antitoxin pair type II binding
JVX94_RS18035	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JVX94_RS18040	COG1647	Serine aminopeptidase, S33
JVX94_RS18045	COG0557	exoribonuclease II activity
JVX94_RS18050	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JVX94_RS18095	COG1937	Protein conserved in bacteria
JVX94_RS18100	COG2608	mercury ion transmembrane transporter activity
JVX94_RS18105	COG2217	Heavy metal translocating P-type atpase
JVX94_RS18115	COG1027	Aspartate ammonia-lyase
JVX94_RS18120	COG4191	Histidine kinase
JVX94_RS18125	COG0784	Response regulator, receiver
JVX94_RS18130	COG3226	Transcriptional regulator
JVX94_RS18140	COG0803	Belongs to the bacterial solute-binding protein 9 family
JVX94_RS18145	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JVX94_RS18150	COG1121	(ABC) transporter
JVX94_RS18155	COG2217	Heavy metal translocating P-type atpase
JVX94_RS18160	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JVX94_RS18165	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
JVX94_RS18170	COG2860	membrane
JVX94_RS18175	COG0025	NhaP-type Na H and K H
JVX94_RS18180	COG1940	carbohydrate kinase activity
JVX94_RS18185	COG0656	L-ascorbic acid biosynthetic process
JVX94_RS18190	COG4149	molybdate abc transporter
JVX94_RS18195	COG0725	ABC transporter, periplasmic molybdate-binding protein
JVX94_RS18200	COG1368	sulfuric ester hydrolase activity
JVX94_RS18205	COG1988	membrane-bound metal-dependent
JVX94_RS18220	COG0531	amino acid
JVX94_RS18225	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JVX94_RS18230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JVX94_RS18235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JVX94_RS18240	COG1120	ATPase activity
JVX94_RS18245	COG0745	RESPONSE REGULATOR receiver
JVX94_RS18250	COG2205	protein histidine kinase activity
JVX94_RS18255	COG1904	glucuronate isomerase
JVX94_RS18260	COG1609	Transcriptional regulator
JVX94_RS18265	COG0246	Mannitol dehydrogenase
JVX94_RS18270	COG2721	sulfolactate sulfo-lyase activity
JVX94_RS18280	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JVX94_RS18285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JVX94_RS18290	COG1120	ATPase activity
JVX94_RS18295	COG2096	Adenosyltransferase
JVX94_RS18300	COG0492	ferredoxin-NADP+ reductase activity
JVX94_RS18305	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JVX94_RS18310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JVX94_RS18320	COG4758	membrane
JVX94_RS18325	COG1842	Phage shock protein A
JVX94_RS18335	COG4758	membrane
JVX94_RS18340	COG4585	Histidine kinase
JVX94_RS18345	COG2197	response regulator
JVX94_RS18360	COG0814	amino acid
JVX94_RS18365	COG0697	spore germination
JVX94_RS18375	COG0114	fumarate hydratase activity
JVX94_RS18385	COG1309	transcriptional regulator
JVX94_RS18395	COG2770	Histidine kinase
JVX94_RS18395	COG2205	protein histidine kinase activity
JVX94_RS18400	COG0745	RESPONSE REGULATOR receiver
JVX94_RS18405	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JVX94_RS18410	COG1028	Short-chain dehydrogenase reductase Sdr
JVX94_RS18420	COG1120	ATPase activity
JVX94_RS18430	COG5577	PFAM Coat F domain
JVX94_RS18445	COG1024	Enoyl-CoA hydratase
JVX94_RS18445	COG1250	3-hydroxyacyl-CoA dehydrogenase
JVX94_RS18450	COG0183	Belongs to the thiolase family
JVX94_RS18455	COG1960	acyl-CoA dehydrogenase activity
JVX94_RS18460	COG1393	Belongs to the ArsC family
JVX94_RS18465	COG0509	glycine decarboxylation via glycine cleavage system
JVX94_RS18475	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JVX94_RS18480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JVX94_RS18490	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JVX94_RS18495	COG2011	ABC-type metal ion transport system permease component
JVX94_RS18500	COG1464	Belongs to the NlpA lipoprotein family
JVX94_RS18505	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JVX94_RS18515	COG0396	ATPase activity
JVX94_RS18520	COG0719	Fe-S assembly protein
JVX94_RS18525	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JVX94_RS18530	COG0822	iron-sulfur transferase activity
JVX94_RS18535	COG0719	Fe-S assembly protein
JVX94_RS18540	COG1309	transcriptional regulator
JVX94_RS18545	COG1090	epimerase
JVX94_RS18550	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JVX94_RS18560	COG2311	Membrane
JVX94_RS18565	COG0745	RESPONSE REGULATOR receiver
JVX94_RS18570	COG5002	protein histidine kinase activity
JVX94_RS18570	COG0642	Histidine kinase
JVX94_RS18590	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JVX94_RS18595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JVX94_RS18600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JVX94_RS18610	COG2356	endonuclease I
JVX94_RS18615	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JVX94_RS18620	COG2814	Major facilitator Superfamily
JVX94_RS18630	COG2140	Oxalate decarboxylase
JVX94_RS18635	COG2508	Transcriptional regulator
JVX94_RS18640	COG1801	Protein of unknown function DUF72
JVX94_RS18645	COG0737	Belongs to the 5'-nucleotidase family
JVX94_RS18650	COG3377	Domain of unknown function (DUF1805)
JVX94_RS18665	COG0739	heme binding
JVX94_RS18670	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JVX94_RS18680	COG4470	Protein conserved in bacteria
JVX94_RS18685	COG2445	Protein of unknown function DUF86
JVX94_RS18690	COG0647	UMP catabolic process
JVX94_RS18695	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JVX94_RS18700	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JVX94_RS18705	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JVX94_RS18710	COG0460	homoserine dehydrogenase
JVX94_RS18715	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JVX94_RS18720	COG0083	homoserine kinase activity
JVX94_RS18725	COG1506	peptidase
JVX94_RS18725	COG0823	Involved in the tonB-independent uptake of proteins
JVX94_RS18725	COG4946	Tricorn protease homolog
JVX94_RS18730	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
JVX94_RS18735	COG4837	Protein of unknown function (DUF1462)
JVX94_RS18745	COG1252	NADH dehydrogenase
JVX94_RS18750	COG4844	belongs to the
JVX94_RS18755	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JVX94_RS18760	COG0316	Belongs to the HesB IscA family
JVX94_RS18765	COG5504	Zn-dependent protease
JVX94_RS18770	COG0789	Transcriptional regulator
JVX94_RS18780	COG0492	ferredoxin-NADP+ reductase activity
JVX94_RS18785	COG1252	NADH dehydrogenase
JVX94_RS18800	COG3584	3D domain protein
JVX94_RS18805	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
JVX94_RS18810	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JVX94_RS18815	COG2056	Na+-H+ antiporter family
JVX94_RS18820	COG4326	sporulation control protein
JVX94_RS18825	COG1268	BioY protein
JVX94_RS18830	COG0686	Belongs to the AlaDH PNT family
JVX94_RS18835	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JVX94_RS18835	COG2508	Transcriptional regulator
JVX94_RS18840	COG4842	Belongs to the WXG100 family
JVX94_RS18845	COG5417	Belongs to the EsaB family
JVX94_RS18850	COG4499	WXG100 protein secretion system (Wss), protein YukC
JVX94_RS18855	COG0433	COG0433 Predicted ATPase
JVX94_RS18855	COG1674	ftsk spoiiie
JVX94_RS18860	COG1511	domain protein
JVX94_RS18870	COG1028	Short-chain dehydrogenase reductase Sdr
JVX94_RS18875	COG1418	mRNA catabolic process
JVX94_RS18890	COG0628	permease
JVX94_RS18910	COG5506	Protein of unknown function (DUF1694)
JVX94_RS18915	COG1335	isochorismatase
JVX94_RS18920	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JVX94_RS18925	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
JVX94_RS18940	COG0142	geranyltranstransferase activity
JVX94_RS18950	COG4585	Histidine kinase
JVX94_RS18955	COG2197	response regulator
JVX94_RS18960	COG2050	protein possibly involved in aromatic compounds catabolism
JVX94_RS18965	COG1320	monovalent cation:proton antiporter activity
JVX94_RS18970	COG2212	antiporter activity
JVX94_RS18975	COG1863	multisubunit Na H antiporter MnhE subunit
JVX94_RS18980	COG0651	ATP synthesis coupled electron transport
JVX94_RS18985	COG1006	Multisubunit Na H antiporter MnhC subunit
JVX94_RS18990	COG2111	Na H antiporter
JVX94_RS18995	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JVX94_RS18995	COG2111	Na H antiporter
JVX94_RS19005	COG3493	citrate carrier protein
JVX94_RS19010	COG1079	Belongs to the binding-protein-dependent transport system permease family
JVX94_RS19015	COG4603	Belongs to the binding-protein-dependent transport system permease family
JVX94_RS19020	COG3845	ABC transporter
JVX94_RS19025	COG1744	ABC transporter substrate-binding protein PnrA-like
JVX94_RS19030	COG4565	transcriptional regulatory protein
JVX94_RS19035	COG3290	protein histidine kinase activity
JVX94_RS19045	COG3011	Protein conserved in bacteria
JVX94_RS19050	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JVX94_RS19055	COG2814	Major facilitator Superfamily
JVX94_RS19060	COG5018	Exonuclease
JVX94_RS19075	COG2205	protein histidine kinase activity
JVX94_RS19080	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JVX94_RS19090	COG2267	carboxylic ester hydrolase activity
JVX94_RS19095	COG1522	sequence-specific DNA binding
JVX94_RS19100	COG0436	Aminotransferase
JVX94_RS19105	COG1098	S1 RNA binding domain
JVX94_RS19110	COG2155	Conserved Protein
JVX94_RS19115	COG1979	alcohol dehydrogenase
JVX94_RS19120	COG1979	alcohol dehydrogenase
JVX94_RS19125	COG0166	Belongs to the GPI family
JVX94_RS19140	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JVX94_RS19150	COG2738	Putative neutral zinc metallopeptidase
JVX94_RS19155	COG1253	flavin adenine dinucleotide binding
JVX94_RS19160	COG0432	Pfam Uncharacterised protein family UPF0047
JVX94_RS19165	COG2070	2-Nitropropane dioxygenase
JVX94_RS19180	COG0840	transmembrane signaling receptor activity
JVX94_RS19185	COG0840	transmembrane signaling receptor activity
JVX94_RS19190	COG0840	transmembrane signaling receptor activity
JVX94_RS19195	COG0840	transmembrane signaling receptor activity
JVX94_RS19200	COG0693	protein deglycase activity
JVX94_RS19205	COG0673	inositol 2-dehydrogenase activity
JVX94_RS19215	COG0628	permease
JVX94_RS19230	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JVX94_RS19240	COG1396	sequence-specific DNA binding
JVX94_RS19260	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
JVX94_RS19270	COG1595	DNA-templated transcription, initiation
JVX94_RS19275	COG5484	DNA packaging
JVX94_RS19280	COG1783	phage Terminase large subunit
JVX94_RS19285	COG5518	Phage portal protein
JVX94_RS19290	COG0338	D12 class N6 adenine-specific DNA methyltransferase
JVX94_RS19295	COG4653	Phage capsid family
JVX94_RS19345	COG5280	Phage tail tape measure protein TP901
JVX94_RS19345	COG5280	Phage tail tape measure protein TP901
JVX94_RS19345	COG3953	SLT domain
JVX94_RS19345	COG3953	SLT domain
JVX94_RS19350	COG1652	LysM domain
JVX94_RS19355	COG4193	domain, Protein
JVX94_RS19365	COG3628	GPW Gp25 family protein
JVX94_RS19370	COG3299	homolog of phage Mu protein gp47
JVX94_RS19375	COG3778	Protein conserved in bacteria
JVX94_RS19420	COG3409	Peptidoglycan-binding domain 1 protein
JVX94_RS19420	COG5632	N-Acetylmuramoyl-L-alanine amidase
JVX94_RS19435	COG1510	regulation of RNA biosynthetic process
JVX94_RS19440	COG1012	belongs to the aldehyde dehydrogenase family
JVX94_RS19445	COG1454	alcohol dehydrogenase
JVX94_RS19450	COG2318	DinB family
JVX94_RS19455	COG1585	Membrane protein implicated in regulation of membrane protease activity
JVX94_RS19460	COG2268	Band 7 protein
JVX94_RS19465	COG0772	Belongs to the SEDS family
JVX94_RS19470	COG0772	Belongs to the SEDS family
JVX94_RS19475	COG3339	Conserved Protein
JVX94_RS19480	COG1247	-acetyltransferase
JVX94_RS19485	COG3859	Proton-coupled thiamine transporter YuaJ