locus-tag	class	description
L3V45_RS00010	COG0592	DNA-directed DNA polymerase activity
L3V45_RS00015	COG2501	S4 domain
L3V45_RS00030	COG0187	DNA topoisomerase II activity
L3V45_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
L3V45_RS00070	COG0516	GMP reductase activity
L3V45_RS00070	COG0517	IMP dehydrogenase activity
L3V45_RS00075	COG1686	Belongs to the peptidase S11 family
L3V45_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
L3V45_RS00105	COG1428	Deoxynucleoside kinase
L3V45_RS00110	COG1428	Deoxynucleoside kinase
L3V45_RS00115	COG1388	LysM domain
L3V45_RS00115	COG3858	chitin binding
L3V45_RS00120	COG1335	isochorismatase
L3V45_RS00125	COG0590	tRNA wobble adenosine to inosine editing
L3V45_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
L3V45_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
L3V45_RS00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
L3V45_RS00195	COG3853	Toxic anion resistance protein (TelA)
L3V45_RS00200	COG1982	Orn Lys Arg decarboxylase major
L3V45_RS00210	COG3870	Protein conserved in bacteria
L3V45_RS00215	COG1728	Protein conserved in bacteria
L3V45_RS00220	COG0470	DNA polymerase III
L3V45_RS00225	COG1774	PSP1 C-terminal conserved region
L3V45_RS00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
L3V45_RS00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
L3V45_RS00250	COG2002	toxin-antitoxin pair type II binding
L3V45_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L3V45_RS00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L3V45_RS00260	COG0084	hydrolase, TatD family'
L3V45_RS00265	COG3583	domain protein
L3V45_RS00265	COG3584	3D domain protein
L3V45_RS00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
L3V45_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
L3V45_RS00285	COG4466	Protein conserved in bacteria
L3V45_RS00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
L3V45_RS00305	COG0251	oxidation-reduction process
L3V45_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L3V45_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
L3V45_RS00345	COG2002	toxin-antitoxin pair type II binding
L3V45_RS00350	COG2244	polysaccharide biosynthetic process
L3V45_RS00355	COG3956	TIGRFAM MazG family protein
L3V45_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
L3V45_RS00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
L3V45_RS00380	COG1098	S1 RNA binding domain
L3V45_RS00395	COG2208	phosphoserine phosphatase activity
L3V45_RS00400	COG2304	oxidoreductase activity
L3V45_RS00405	COG0515	serine threonine protein kinase
L3V45_RS00410	COG0037	tRNA processing
L3V45_RS00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
L3V45_RS00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L3V45_RS00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L3V45_RS00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L3V45_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
L3V45_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
L3V45_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L3V45_RS00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
L3V45_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
L3V45_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
L3V45_RS00475	COG1396	sequence-specific DNA binding
L3V45_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L3V45_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
L3V45_RS00565	COG4463	regulation of RNA biosynthetic process
L3V45_RS00570	COG3880	PFAM UvrB UvrC protein
L3V45_RS00580	COG0542	response to heat
L3V45_RS00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
L3V45_RS00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
L3V45_RS00595	COG4956	integral membrane protein (PIN domain superfamily)
L3V45_RS00615	COG1045	serine acetyltransferase
L3V45_RS00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
L3V45_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L3V45_RS00635	COG3688	RNA-binding protein containing a PIN domain
L3V45_RS00640	COG1595	DNA-templated transcription, initiation
L3V45_RS00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
L3V45_RS00655	COG0250	Participates in transcription elongation, termination and antitermination
L3V45_RS00680	COG2813	Specifically methylates the guanine in position
L3V45_RS00695	COG1358	cellular component organization or biogenesis
L3V45_RS00720	COG0596	Alpha beta hydrolase
L3V45_RS00830	COG0201	protein transport
L3V45_RS00840	COG0024	Methionine aminopeptidase
L3V45_RS00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
L3V45_RS00880	COG1122	ATPase activity
L3V45_RS00885	COG1122	ATPase activity
L3V45_RS00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
L3V45_RS00910	COG2226	methyltransferase
L3V45_RS00915	COG2318	DinB family
L3V45_RS00925	COG0860	N-Acetylmuramoyl-L-alanine amidase
L3V45_RS00930	COG0489	protein tyrosine kinase activity
L3V45_RS00940	COG2194	sulfuric ester hydrolase activity
L3V45_RS00945	COG0726	polysaccharide deacetylase
L3V45_RS01005	COG0738	Major facilitator superfamily
L3V45_RS01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L3V45_RS01025	COG0659	secondary active sulfate transmembrane transporter activity
L3V45_RS01030	COG0385	Bile acid
L3V45_RS01035	COG2819	hydrolase of the alpha beta superfamily
L3V45_RS01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L3V45_RS01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L3V45_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
L3V45_RS01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
L3V45_RS01055	COG2207	Transcriptional regulator
L3V45_RS01060	COG3876	Protein conserved in bacteria
L3V45_RS01065	COG1472	Belongs to the glycosyl hydrolase 3 family
L3V45_RS01070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L3V45_RS01075	COG1263	PTS System
L3V45_RS01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L3V45_RS01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L3V45_RS01090	COG1683	Conserved Protein
L3V45_RS01120	COG1595	DNA-templated transcription, initiation
L3V45_RS01125	COG5662	AntiSigma factor
L3V45_RS01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
L3V45_RS01135	COG4856	YbbR-like protein
L3V45_RS01185	COG1346	cytolysis
L3V45_RS01190	COG1380	Effector of murein hydrolase LrgA
L3V45_RS01195	COG1846	Transcriptional regulator
L3V45_RS01200	COG1113	amino acid transport
L3V45_RS01205	COG1011	Hydrolase
L3V45_RS01210	COG4585	Histidine kinase
L3V45_RS01215	COG2197	response regulator
L3V45_RS01220	COG1131	(ABC) transporter
L3V45_RS01260	COG0531	amino acid
L3V45_RS01265	COG0584	glycerophosphoryl diester phosphodiesterase
L3V45_RS01270	COG2271	Major facilitator Superfamily
L3V45_RS01280	COG2368	4-hydroxyphenylacetate
L3V45_RS01290	COG3409	Peptidoglycan-binding domain 1 protein
L3V45_RS01305	COG0371	Dehydrogenase
L3V45_RS01315	COG1183	phosphatidylcholine synthase activity
L3V45_RS01320	COG0586	Pfam SNARE associated Golgi protein
L3V45_RS01325	COG0688	phosphatidylethanolamine metabolic process
L3V45_RS01340	COG1301	dicarboxylic acid transport
L3V45_RS01345	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L3V45_RS01350	COG0833	amino acid
L3V45_RS01355	COG2040	homocysteine
L3V45_RS01360	COG1115	amino acid carrier protein
L3V45_RS01365	COG2066	Belongs to the glutaminase family
L3V45_RS01370	COG4191	Histidine kinase
L3V45_RS01375	COG0784	Response regulator, receiver
L3V45_RS01380	COG3173	Aminoglycoside phosphotransferase
L3V45_RS01390	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
L3V45_RS01395	COG0778	Nitroreductase
L3V45_RS01400	COG0346	lactoylglutathione lyase activity
L3V45_RS01405	COG2259	Doxx family
L3V45_RS01410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L3V45_RS01420	COG3773	Cell wall hydrolase
L3V45_RS01425	COG3540	Alkaline phosphatase
L3V45_RS01430	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
L3V45_RS01435	COG0805	protein transport
L3V45_RS01445	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
L3V45_RS01450	COG0477	Major facilitator Superfamily
L3V45_RS01455	COG1309	transcriptional regulator
L3V45_RS01460	COG0252	asparaginase activity
L3V45_RS01465	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
L3V45_RS01470	COG1405	negative regulation of cell septum assembly
L3V45_RS01470	COG3012	SEC-C Motif Domain Protein
L3V45_RS01475	COG0667	Aldo Keto reductase
L3V45_RS01485	COG1595	DNA-templated transcription, initiation
L3V45_RS01490	COG1595	DNA-templated transcription, initiation
L3V45_RS01495	COG1876	peptidase activity
L3V45_RS01500	COG0457	Tetratricopeptide repeat
L3V45_RS01505	COG1028	Short-chain dehydrogenase reductase Sdr
L3V45_RS01510	COG0366	Alpha amylase catalytic
L3V45_RS01515	COG0803	Belongs to the bacterial solute-binding protein 9 family
L3V45_RS01520	COG1121	(ABC) transporter
L3V45_RS01525	COG1108	ABC-type Mn2 Zn2 transport systems permease components
L3V45_RS01530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L3V45_RS01535	COG2310	stress, protein
L3V45_RS01540	COG2310	stress, protein
L3V45_RS01545	COG2310	stress, protein
L3V45_RS01550	COG0861	Integral membrane protein TerC family
L3V45_RS01560	COG3853	Toxic anion resistance protein (TelA)
L3V45_RS01565	COG0477	Major facilitator Superfamily
L3V45_RS01570	COG4175	Glycine betaine
L3V45_RS01570	COG0517	IMP dehydrogenase activity
L3V45_RS01575	COG4176	ABC-type proline glycine betaine transport system permease component
L3V45_RS01580	COG2113	Glycine betaine
L3V45_RS01585	COG1473	amidohydrolase
L3V45_RS01590	COG1288	antiporter activity
L3V45_RS01600	COG0366	Alpha amylase catalytic
L3V45_RS01610	COG2814	Major facilitator Superfamily
L3V45_RS01615	COG1846	Transcriptional regulator
L3V45_RS01620	COG1280	lysine exporter protein (LysE YggA)
L3V45_RS01625	COG3403	YqcI/YcgG family
L3V45_RS01630	COG1113	amino acid transport
L3V45_RS01635	COG3665	Urea carboxylase-associated protein
L3V45_RS01650	COG1660	Displays ATPase and GTPase activities
L3V45_RS01660	COG2271	Major facilitator Superfamily
L3V45_RS01665	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
L3V45_RS01670	COG3458	cephalosporin-C deacetylase activity
L3V45_RS01675	COG3541	Predicted nucleotidyltransferase
L3V45_RS01680	COG0506	proline dehydrogenase activity
L3V45_RS01685	COG1012	belongs to the aldehyde dehydrogenase family
L3V45_RS01690	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L3V45_RS01695	COG2508	Transcriptional regulator
L3V45_RS01705	COG1587	Uroporphyrinogen-III synthase
L3V45_RS01705	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
L3V45_RS01710	COG2146	nitrite reductase [NAD(P)H] activity
L3V45_RS01715	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L3V45_RS01725	COG0523	cobalamin synthesis protein
L3V45_RS01730	COG1063	alcohol dehydrogenase
L3V45_RS01735	COG1714	RDD family
L3V45_RS01755	COG3209	COG3209 Rhs family protein
L3V45_RS01760	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
L3V45_RS01765	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
L3V45_RS01770	COG1733	regulation of RNA biosynthetic process
L3V45_RS01775	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L3V45_RS01795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L3V45_RS01800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L3V45_RS01805	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
L3V45_RS01820	COG2364	Membrane
L3V45_RS01825	COG1126	abc transporter atp-binding protein
L3V45_RS01830	COG0765	amino acid transport
L3V45_RS01835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L3V45_RS01840	COG0583	DNA-binding transcription factor activity
L3V45_RS01845	COG0163	prenyltransferase activity
L3V45_RS01850	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
L3V45_RS01865	COG3104	oligopeptide transport
L3V45_RS01870	COG5434	Belongs to the glycosyl hydrolase 28 family
L3V45_RS01880	COG0697	spore germination
L3V45_RS01890	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L3V45_RS01895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L3V45_RS01900	COG0456	acetyltransferase
L3V45_RS01905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L3V45_RS01910	COG0765	amino acid transport
L3V45_RS01915	COG1126	abc transporter atp-binding protein
L3V45_RS01920	COG1473	amidohydrolase
L3V45_RS01925	COG2079	MmgE PrpD family protein
L3V45_RS01930	COG1136	(ABC) transporter
L3V45_RS01935	COG0577	efflux transmembrane transporter activity
L3V45_RS01940	COG0745	RESPONSE REGULATOR receiver
L3V45_RS01945	COG5002	protein histidine kinase activity
L3V45_RS01945	COG3850	Histidine kinase
L3V45_RS01950	COG0457	Tetratricopeptide repeat
L3V45_RS01965	COG0527	aspartate kinase activity
L3V45_RS01970	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L3V45_RS01975	COG4605	iron ion homeostasis
L3V45_RS01980	COG4604	ABC transporter, ATP-binding protein
L3V45_RS01985	COG4607	ABC-type enterochelin transport system periplasmic component
L3V45_RS01990	COG2814	Major facilitator Superfamily
L3V45_RS01995	COG1309	transcriptional regulator
L3V45_RS02000	COG0778	Nitroreductase
L3V45_RS02005	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
L3V45_RS02010	COG0640	Transcriptional regulator
L3V45_RS02015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L3V45_RS02020	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L3V45_RS02025	COG1012	belongs to the aldehyde dehydrogenase family
L3V45_RS02030	COG4975	Glucose uptake
L3V45_RS02035	COG1028	Short-chain dehydrogenase reductase Sdr
L3V45_RS02040	COG4549	nuclear export factor GLE1
L3V45_RS02045	COG1276	copper resistance
L3V45_RS02045	COG2372	response to copper ion
L3V45_RS02050	COG1349	DNA-binding transcription factor activity
L3V45_RS02060	COG2213	PTS system mannitol-specific
L3V45_RS02065	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
L3V45_RS02075	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
L3V45_RS02085	COG0561	phosphatase activity
L3V45_RS02095	COG1914	H( )-stimulated, divalent metal cation uptake system
L3V45_RS02105	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
L3V45_RS02110	COG1984	allophanate hydrolase subunit 2
L3V45_RS02115	COG1414	Transcriptional regulator
L3V45_RS02120	COG2755	lipolytic protein G-D-S-L family
L3V45_RS02130	COG2329	Antibiotic biosynthesis monooxygenase
L3V45_RS02135	COG0768	penicillin binding
L3V45_RS02140	COG4989	oxidoreductase activity
L3V45_RS02145	COG3711	transcriptional antiterminator
L3V45_RS02150	COG0318	PFAM AMP-dependent synthetase and ligase
L3V45_RS02155	COG1028	Short-chain dehydrogenase reductase Sdr
L3V45_RS02160	COG1917	Cupin 2, conserved barrel domain protein
L3V45_RS02165	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L3V45_RS02170	COG3871	stress protein (general stress protein 26)
L3V45_RS02180	COG2814	Major facilitator Superfamily
L3V45_RS02185	COG1522	sequence-specific DNA binding
L3V45_RS02190	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
L3V45_RS02190	COG0551	DNA topoisomerase type I activity
L3V45_RS02195	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
L3V45_RS02200	COG3706	GGDEF domain
L3V45_RS02205	COG5298	Protein conserved in bacteria
L3V45_RS02210	COG1215	transferase activity, transferring glycosyl groups
L3V45_RS02220	COG0531	amino acid
L3V45_RS02225	COG0494	nUDIX hydrolase
L3V45_RS02230	COG0028	Belongs to the TPP enzyme family
L3V45_RS02255	COG1914	H( )-stimulated, divalent metal cation uptake system
L3V45_RS02275	COG2076	Multidrug Resistance protein
L3V45_RS02280	COG2217	Heavy metal translocating P-type atpase
L3V45_RS02285	COG3729	General stress protein
L3V45_RS02290	COG0662	Cupin 2, conserved barrel domain protein
L3V45_RS02295	COG2329	Antibiotic biosynthesis monooxygenase
L3V45_RS02300	COG3546	catalase activity
L3V45_RS02305	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
L3V45_RS02310	COG3290	protein histidine kinase activity
L3V45_RS02315	COG4565	transcriptional regulatory protein
L3V45_RS02320	COG1301	dicarboxylic acid transport
L3V45_RS02325	COG0628	permease
L3V45_RS02330	COG1131	(ABC) transporter
L3V45_RS02335	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
L3V45_RS02345	COG1960	acyl-CoA dehydrogenase activity
L3V45_RS02360	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
L3V45_RS02365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L3V45_RS02375	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
L3V45_RS02380	COG0513	Belongs to the DEAD box helicase family
L3V45_RS02385	COG3402	PFAM membrane-flanked domain
L3V45_RS02390	COG3428	Bacterial PH domain
L3V45_RS02395	COG0705	Rhomboid family
L3V45_RS02405	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
L3V45_RS02410	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
L3V45_RS02415	COG0864	Transcriptional regulator
L3V45_RS02420	COG2337	Toxic component of a toxin-antitoxin (TA) module
L3V45_RS02425	COG1366	Belongs to the anti-sigma-factor antagonist family
L3V45_RS02430	COG1366	Belongs to the anti-sigma-factor antagonist family
L3V45_RS02435	COG2172	sigma factor antagonist activity
L3V45_RS02440	COG2208	phosphoserine phosphatase activity
L3V45_RS02445	COG1366	Belongs to the anti-sigma-factor antagonist family
L3V45_RS02455	COG1191	sigma factor activity
L3V45_RS02460	COG2208	phosphoserine phosphatase activity
L3V45_RS02465	COG2183	response to ionizing radiation
L3V45_RS02570	COG0477	Major facilitator Superfamily
L3V45_RS02580	COG1764	response to oxidative stress
L3V45_RS02585	COG1846	Transcriptional regulator
L3V45_RS02595	COG1959	2 iron, 2 sulfur cluster binding
L3V45_RS02600	COG2910	NAD(P)H-binding
L3V45_RS02605	COG1278	Cold shock
L3V45_RS02615	COG1937	Protein conserved in bacteria
L3V45_RS02620	COG2210	Belongs to the sulfur carrier protein TusA family
L3V45_RS02630	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
L3V45_RS02630	COG0425	Belongs to the sulfur carrier protein TusA family
L3V45_RS02640	COG0425	Belongs to the sulfur carrier protein TusA family
L3V45_RS02645	COG0730	response to heat
L3V45_RS02650	COG1794	racemase activity, acting on amino acids and derivatives
L3V45_RS02665	COG3621	Patatin-like phospholipase
L3V45_RS02675	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L3V45_RS02680	COG1802	Transcriptional regulator
L3V45_RS02685	COG0251	oxidation-reduction process
L3V45_RS02690	COG0814	amino acid
L3V45_RS02695	COG1473	amidohydrolase
L3V45_RS02700	COG1917	Cupin 2, conserved barrel domain protein
L3V45_RS02700	COG2207	Transcriptional regulator
L3V45_RS02710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L3V45_RS02715	COG0477	Major facilitator Superfamily
L3V45_RS02735	COG0277	FAD linked oxidase domain protein
L3V45_RS02770	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L3V45_RS02795	COG1064	alcohol dehydrogenase
L3V45_RS02800	COG0789	Transcriptional regulator
L3V45_RS02820	COG2814	Major facilitator Superfamily
L3V45_RS02825	COG1309	transcriptional regulator
L3V45_RS02830	COG5577	PFAM Coat F domain
L3V45_RS02840	COG1063	alcohol dehydrogenase
L3V45_RS02845	COG5577	PFAM Coat F domain
L3V45_RS02855	COG4585	Histidine kinase
L3V45_RS02860	COG2197	response regulator
L3V45_RS02865	COG2409	Drug exporters of the RND superfamily
L3V45_RS02870	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
L3V45_RS02875	COG0488	(ABC) transporter
L3V45_RS02880	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L3V45_RS02885	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L3V45_RS02895	COG2814	Major facilitator Superfamily
L3V45_RS02900	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
L3V45_RS02910	COG0730	response to heat
L3V45_RS02915	COG0456	acetyltransferase
L3V45_RS02920	COG0789	Transcriptional regulator
L3V45_RS02920	COG4978	Transcriptional regulator
L3V45_RS02925	COG0697	spore germination
L3V45_RS02930	COG1051	belongs to the nudix hydrolase family
L3V45_RS02935	COG2226	methyltransferase
L3V45_RS02940	COG0473	3-isopropylmalate dehydrogenase activity
L3V45_RS02945	COG1802	Transcriptional regulator
L3V45_RS02950	COG1819	glycosyl
L3V45_RS02965	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L3V45_RS02975	COG1388	LysM domain
L3V45_RS02980	COG2814	Major facilitator Superfamily
L3V45_RS02985	COG2188	Transcriptional regulator
L3V45_RS02990	COG2186	Transcriptional regulator
L3V45_RS02995	COG2807	transmembrane transport
L3V45_RS03000	COG2076	Multidrug Resistance protein
L3V45_RS03005	COG2076	Multidrug Resistance protein
L3V45_RS03010	COG1309	transcriptional regulator
L3V45_RS03015	COG0531	amino acid
L3V45_RS03025	COG3832	glyoxalase III activity
L3V45_RS03030	COG0604	alcohol dehydrogenase
L3V45_RS03035	COG2814	Major facilitator Superfamily
L3V45_RS03075	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
L3V45_RS03080	COG0802	atpase or kinase
L3V45_RS03085	COG1214	PFAM Peptidase M22, glycoprotease
L3V45_RS03090	COG0456	acetyltransferase
L3V45_RS03095	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
L3V45_RS03100	COG0488	(ABC) transporter
L3V45_RS03115	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
L3V45_RS03120	COG0805	protein transport
L3V45_RS03130	COG1266	CAAX protease self-immunity
L3V45_RS03150	COG0457	Tetratricopeptide repeat
L3V45_RS03155	COG1063	alcohol dehydrogenase
L3V45_RS03160	COG2211	Major facilitator Superfamily
L3V45_RS03165	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L3V45_RS03175	COG1842	Phage shock protein A
L3V45_RS03180	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
L3V45_RS03185	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
L3V45_RS03190	COG4260	virion core protein, lumpy skin disease virus
L3V45_RS03195	COG2755	lipolytic protein G-D-S-L family
L3V45_RS03195	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
L3V45_RS03205	COG1595	DNA-templated transcription, initiation
L3V45_RS03210	COG1063	alcohol dehydrogenase
L3V45_RS03215	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
L3V45_RS03220	COG0823	Involved in the tonB-independent uptake of proteins
L3V45_RS03235	COG2132	Multicopper oxidase
L3V45_RS03240	COG1113	amino acid transport
L3V45_RS03245	COG0714	Associated with various cellular activities
L3V45_RS03250	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
L3V45_RS03255	COG1305	Transglutaminase-like
L3V45_RS03275	COG2252	PERMEase
L3V45_RS03280	COG3064	Membrane
L3V45_RS03300	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
L3V45_RS03305	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
L3V45_RS03310	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
L3V45_RS03315	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
L3V45_RS03320	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
L3V45_RS03335	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
L3V45_RS03345	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
L3V45_RS03350	COG0138	bifunctional purine biosynthesis protein purh
L3V45_RS03355	COG0151	Belongs to the GarS family
L3V45_RS03365	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
L3V45_RS03370	COG1470	cell adhesion involved in biofilm formation
L3V45_RS03375	COG4496	protein, YerC YecD
L3V45_RS03380	COG0069	glutamate synthase activity
L3V45_RS03390	COG0210	DNA helicase
L3V45_RS03400	COG4851	CamS sex pheromone cAM373 precursor
L3V45_RS03405	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
L3V45_RS03410	COG1285	pathogenesis
L3V45_RS03415	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L3V45_RS03435	COG1309	transcriptional regulator
L3V45_RS03440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L3V45_RS03445	COG1597	lipid kinase activity
L3V45_RS03450	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
L3V45_RS03460	COG1131	(ABC) transporter
L3V45_RS03505	COG5444	nuclease activity
L3V45_RS03535	COG3546	catalase activity
L3V45_RS03540	COG0454	-acetyltransferase
L3V45_RS03550	COG2323	membrane
L3V45_RS03555	COG2329	Antibiotic biosynthesis monooxygenase
L3V45_RS03560	COG0346	lactoylglutathione lyase activity
L3V45_RS03565	COG1366	Belongs to the anti-sigma-factor antagonist family
L3V45_RS03570	COG5583	Uncharacterized small protein (DUF2292)
L3V45_RS03575	COG0196	riboflavin kinase activity
L3V45_RS03580	COG0670	Belongs to the BI1 family
L3V45_RS03585	COG1846	Transcriptional regulator
L3V45_RS03590	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L3V45_RS03600	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
L3V45_RS03600	COG2124	cytochrome p450
L3V45_RS03605	COG1368	sulfuric ester hydrolase activity
L3V45_RS03610	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
L3V45_RS03615	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L3V45_RS03620	COG1442	glycosyl transferase family 8
L3V45_RS03625	COG1216	Glycosyl transferase, family 2
L3V45_RS03630	COG1442	glycosyl transferase family 8
L3V45_RS03635	COG2223	nitrite transmembrane transporter activity
L3V45_RS03640	COG0531	amino acid
L3V45_RS03645	COG1012	belongs to the aldehyde dehydrogenase family
L3V45_RS03650	COG0840	transmembrane signaling receptor activity
L3V45_RS03655	COG1028	Short-chain dehydrogenase reductase Sdr
L3V45_RS03660	COG0457	Tetratricopeptide repeat
L3V45_RS03660	COG0463	Glycosyl transferase, family 2
L3V45_RS03665	COG0488	(ABC) transporter
L3V45_RS03670	COG0789	Transcriptional regulator
L3V45_RS03675	COG2814	Major facilitator Superfamily
L3V45_RS03680	COG0488	(ABC) transporter
L3V45_RS03685	COG0513	Belongs to the DEAD box helicase family
L3V45_RS03695	COG2130	NADP-dependent
L3V45_RS03710	COG3866	Pectate lyase
L3V45_RS03715	COG0471	metal ion transport
L3V45_RS03750	COG0745	RESPONSE REGULATOR receiver
L3V45_RS03750	COG2972	Histidine kinase
L3V45_RS03760	COG3279	Response regulator of the LytR AlgR family
L3V45_RS03770	COG3764	Sortase (surface protein transpeptidase)
L3V45_RS03775	COG3290	protein histidine kinase activity
L3V45_RS03780	COG4565	transcriptional regulatory protein
L3V45_RS03785	COG3181	Tripartite tricarboxylate transporter family receptor
L3V45_RS03790	COG2851	Citrate transporter
L3V45_RS03795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L3V45_RS03800	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
L3V45_RS03810	COG2258	MOSC domain
L3V45_RS03830	COG0024	Methionine aminopeptidase
L3V45_RS03835	COG1263	PTS System
L3V45_RS03835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L3V45_RS03845	COG1368	sulfuric ester hydrolase activity
L3V45_RS03855	COG0071	Belongs to the small heat shock protein (HSP20) family
L3V45_RS03870	COG1263	PTS System
L3V45_RS03870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L3V45_RS03875	COG0366	Alpha amylase catalytic
L3V45_RS03880	COG2188	Transcriptional regulator
L3V45_RS03885	COG0778	Nitroreductase
L3V45_RS03900	COG0737	Belongs to the 5'-nucleotidase family
L3V45_RS03905	COG0693	protein deglycase activity
L3V45_RS03910	COG1609	Transcriptional regulator
L3V45_RS03925	COG2814	Major facilitator Superfamily
L3V45_RS03935	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
L3V45_RS03940	COG4980	gas vesicle protein
L3V45_RS03945	COG1295	ribonuclease BN
L3V45_RS03950	COG0477	Major facilitator Superfamily
L3V45_RS03955	COG0387	Pfam Sodium calcium exchanger
L3V45_RS03965	COG0668	transmembrane transport
L3V45_RS03970	COG0535	radical SAM domain protein
L3V45_RS03980	COG0726	polysaccharide deacetylase
L3V45_RS03985	COG2084	Dehydrogenase
L3V45_RS03995	COG0598	Magnesium transport protein CorA
L3V45_RS04000	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
L3V45_RS04005	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
L3V45_RS04015	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L3V45_RS04020	COG4637	Psort location Cytoplasmic, score
L3V45_RS04025	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L3V45_RS04030	COG0022	dehydrogenase e1 component
L3V45_RS04035	COG0508	dehydrogenase complex catalyzes the overall conversion of
L3V45_RS04040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L3V45_RS04045	COG3284	Transcriptional regulator
L3V45_RS04055	COG1486	melibiose metabolic process
L3V45_RS04060	COG1737	Transcriptional regulator
L3V45_RS04065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L3V45_RS04065	COG1263	PTS System
L3V45_RS04070	COG1132	(ABC) transporter
L3V45_RS04075	COG1132	(ABC) transporter
L3V45_RS04080	COG2259	Doxx family
L3V45_RS04085	COG2514	catechol 2,3-dioxygenase activity
L3V45_RS04095	COG1695	Transcriptional regulator
L3V45_RS04100	COG2249	NAD(P)H dehydrogenase (quinone) activity
L3V45_RS04105	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
L3V45_RS04110	COG0574	Belongs to the PEP-utilizing enzyme family
L3V45_RS04110	COG3848	Pyruvate phosphate dikinase
L3V45_RS04115	COG2732	(Barnase) inhibitor
L3V45_RS04120	COG2318	DinB family
L3V45_RS04125	COG2814	Major facilitator Superfamily
L3V45_RS04130	COG1846	Transcriptional regulator
L3V45_RS04135	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
L3V45_RS04135	COG0392	lysyltransferase activity
L3V45_RS04140	COG0384	phenazine biosynthesis protein PhzF
L3V45_RS04145	COG0778	Nitroreductase
L3V45_RS04160	COG1090	epimerase
L3V45_RS04175	COG2814	Major facilitator Superfamily
L3V45_RS04185	COG3591	Belongs to the peptidase S1B family
L3V45_RS04200	COG3103	Sh3 type 3 domain protein
L3V45_RS04205	COG5658	integral membrane protein
L3V45_RS04210	COG0596	Alpha beta hydrolase
L3V45_RS04215	COG0463	Glycosyl transferase, family 2
L3V45_RS04220	COG4485	Bacterial membrane protein, YfhO
L3V45_RS04225	COG1988	membrane-bound metal-dependent
L3V45_RS04230	COG1194	a g-specific adenine glycosylase
L3V45_RS04240	COG1028	Short-chain dehydrogenase reductase Sdr
L3V45_RS04260	COG1132	(ABC) transporter
L3V45_RS04265	COG4129	membrane
L3V45_RS04275	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
L3V45_RS04280	COG0735	belongs to the Fur family
L3V45_RS04395	COG3340	Belongs to the peptidase S51 family
L3V45_RS04405	COG0277	FAD linked oxidase domain protein
L3V45_RS04415	COG0747	negative chemotaxis
L3V45_RS04420	COG0601	transmembrane transport
L3V45_RS04425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L3V45_RS04430	COG0444	Belongs to the ABC transporter superfamily
L3V45_RS04435	COG4608	Belongs to the ABC transporter superfamily
L3V45_RS04440	COG0753	catalase activity
L3V45_RS04450	COG1116	anion transmembrane transporter activity
L3V45_RS04455	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L3V45_RS04460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L3V45_RS04480	COG1476	TRANSCRIPTIONal
L3V45_RS04490	COG3382	B3 4 domain protein
L3V45_RS04495	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
L3V45_RS04505	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
L3V45_RS04510	COG0789	Transcriptional regulator
L3V45_RS04515	COG1664	Polymer-forming cytoskeletal
L3V45_RS04520	COG1664	Polymer-forming cytoskeletal
L3V45_RS04525	COG2766	serine protein kinase
L3V45_RS04535	COG1846	Transcriptional regulator
L3V45_RS04540	COG1566	PFAM secretion protein HlyD family protein
L3V45_RS04545	COG2814	Major facilitator Superfamily
L3V45_RS04550	COG0655	NAD(P)H dehydrogenase (quinone) activity
L3V45_RS04565	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
L3V45_RS04570	COG1278	Cold shock
L3V45_RS04575	COG1464	Belongs to the NlpA lipoprotein family
L3V45_RS04580	COG3706	GGDEF domain
L3V45_RS04585	COG1823	symporter activity
L3V45_RS04605	COG5577	PFAM Coat F domain
L3V45_RS04610	COG4085	toxin activity
L3V45_RS04610	COG1525	nuclease
L3V45_RS04610	COG0737	Belongs to the 5'-nucleotidase family
L3V45_RS04615	COG3764	Sortase (surface protein transpeptidase)
L3V45_RS04620	COG0564	pseudouridine synthase activity
L3V45_RS04630	COG0517	IMP dehydrogenase activity
L3V45_RS04635	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L3V45_RS04640	COG3153	acetyltransferase
L3V45_RS04640	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L3V45_RS04645	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
L3V45_RS04650	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
L3V45_RS04655	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
L3V45_RS04665	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
L3V45_RS04670	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L3V45_RS04685	COG0431	NADPH-dependent FMN reductase
L3V45_RS04700	COG1388	LysM domain
L3V45_RS04700	COG0791	NLP P60 protein
L3V45_RS04705	COG1959	2 iron, 2 sulfur cluster binding
L3V45_RS04715	COG2719	SpoVR family
L3V45_RS04720	COG1785	Belongs to the alkaline phosphatase family
L3V45_RS04725	COG0791	NLP P60 protein
L3V45_RS04725	COG1388	LysM domain
L3V45_RS04730	COG0583	DNA-binding transcription factor activity
L3V45_RS04735	COG0372	Belongs to the citrate synthase family
L3V45_RS04740	COG1028	Short-chain dehydrogenase reductase Sdr
L3V45_RS04745	COG0531	amino acid
L3V45_RS04750	COG0733	neurotransmitter:sodium symporter activity
L3V45_RS04765	COG1595	DNA-templated transcription, initiation
L3V45_RS04770	COG0204	Acyl-transferase
L3V45_RS04775	COG1253	flavin adenine dinucleotide binding
L3V45_RS04780	COG0789	Transcriptional regulator
L3V45_RS04785	COG0436	Aminotransferase
L3V45_RS04790	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
L3V45_RS04795	COG1253	flavin adenine dinucleotide binding
L3V45_RS04800	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
L3V45_RS04805	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
L3V45_RS04810	COG0584	glycerophosphoryl diester phosphodiesterase
L3V45_RS04820	COG0668	transmembrane transport
L3V45_RS04825	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
L3V45_RS04830	COG0726	polysaccharide deacetylase
L3V45_RS04835	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L3V45_RS04840	COG3226	Transcriptional regulator
L3V45_RS04850	COG0589	response to stress
L3V45_RS04855	COG1132	(ABC) transporter
L3V45_RS04860	COG1132	(ABC) transporter
L3V45_RS04865	COG0702	epimerase
L3V45_RS04885	COG0189	ligase activity
L3V45_RS04890	COG0189	ligase activity
L3V45_RS04905	COG4335	DNA alkylation repair
L3V45_RS04910	COG0561	phosphatase activity
L3V45_RS04915	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L3V45_RS04925	COG0475	glutathione-regulated potassium exporter activity
L3V45_RS04930	COG0490	domain, Protein
L3V45_RS04940	COG1024	Enoyl-CoA hydratase
L3V45_RS04950	COG4152	abc transporter atp-binding protein
L3V45_RS04955	COG1668	transmembrane transport
L3V45_RS04960	COG0420	3'-5' exonuclease activity
L3V45_RS04965	COG4717	serine-type aminopeptidase activity
L3V45_RS04980	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L3V45_RS05015	COG4980	gas vesicle protein
L3V45_RS05030	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
L3V45_RS05035	COG0537	adenosine 5'-monophosphoramidase activity
L3V45_RS05040	COG1131	(ABC) transporter
L3V45_RS05045	COG4473	ABC transporter
L3V45_RS05055	COG1473	amidohydrolase
L3V45_RS05060	COG3069	C4-dicarboxylate transmembrane transporter activity
L3V45_RS05065	COG2329	Antibiotic biosynthesis monooxygenase
L3V45_RS05070	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L3V45_RS05080	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
L3V45_RS05085	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
L3V45_RS05090	COG1309	transcriptional regulator
L3V45_RS05095	COG1511	domain protein
L3V45_RS05100	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
L3V45_RS05110	COG1363	Peptidase, m42
L3V45_RS05115	COG1301	dicarboxylic acid transport
L3V45_RS05125	COG1234	tRNA 3'-trailer cleavage
L3V45_RS05130	COG0095	Lipoate-protein ligase
L3V45_RS05135	COG0702	epimerase
L3V45_RS05140	COG0318	PFAM AMP-dependent synthetase and ligase
L3V45_RS05150	COG0501	Belongs to the peptidase M48B family
L3V45_RS05155	COG1404	Belongs to the peptidase S8 family
L3V45_RS05160	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
L3V45_RS05165	COG0406	alpha-ribazole phosphatase activity
L3V45_RS05170	COG0183	Belongs to the thiolase family
L3V45_RS05175	COG0318	PFAM AMP-dependent synthetase and ligase
L3V45_RS05180	COG1268	BioY protein
L3V45_RS05185	COG0840	transmembrane signaling receptor activity
L3V45_RS05190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L3V45_RS05190	COG0723	plastoquinol--plastocyanin reductase activity
L3V45_RS05195	COG1028	Short-chain dehydrogenase reductase Sdr
L3V45_RS05205	COG4903	ComK protein
L3V45_RS05215	COG5646	InterPro IPR014922
L3V45_RS05235	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L3V45_RS05250	COG0398	Pfam SNARE associated Golgi protein
L3V45_RS05255	COG0681	Belongs to the peptidase S26 family
L3V45_RS05260	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L3V45_RS05265	COG1846	Transcriptional regulator
L3V45_RS05270	COG3180	Ammonia monooxygenase
L3V45_RS05275	COG2814	Major facilitator Superfamily
L3V45_RS05285	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
L3V45_RS05290	COG2323	membrane
L3V45_RS05305	COG0420	3'-5' exonuclease activity
L3V45_RS05310	COG0419	ATPase involved in DNA repair
L3V45_RS05315	COG1403	HNH endonuclease
L3V45_RS05355	COG0179	Fumarylacetoacetate (FAA) hydrolase
L3V45_RS05370	COG0367	asparagine synthase
L3V45_RS05375	COG1562	ergosterol biosynthetic process
L3V45_RS05380	COG0534	Mate efflux family protein
L3V45_RS05385	COG2207	Transcriptional regulator
L3V45_RS05385	COG1917	Cupin 2, conserved barrel domain protein
L3V45_RS05390	COG1609	Transcriptional regulator
L3V45_RS05395	COG0673	inositol 2-dehydrogenase activity
L3V45_RS05400	COG2318	DinB family
L3V45_RS05405	COG1357	PFAM Pentapeptide repeats (8 copies)
L3V45_RS05410	COG2153	protein acetylation
L3V45_RS05415	COG0646	methionine synthase
L3V45_RS05415	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
L3V45_RS05425	COG2996	Protein conserved in bacteria
L3V45_RS05430	COG1744	ABC transporter substrate-binding protein PnrA-like
L3V45_RS05435	COG0840	transmembrane signaling receptor activity
L3V45_RS05445	COG1307	EDD domain protein, DegV family
L3V45_RS05450	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L3V45_RS05470	COG0561	phosphatase activity
L3V45_RS05475	COG1073	alpha beta
L3V45_RS05480	COG2151	metal-sulfur cluster biosynthetic enzyme
L3V45_RS05490	COG0277	FAD linked oxidase domain protein
L3V45_RS05495	COG2271	Major facilitator Superfamily
L3V45_RS05505	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
L3V45_RS05515	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L3V45_RS05520	COG0505	Belongs to the CarA family
L3V45_RS05525	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
L3V45_RS05530	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
L3V45_RS05545	COG2267	carboxylic ester hydrolase activity
L3V45_RS05555	COG1744	ABC transporter substrate-binding protein PnrA-like
L3V45_RS05570	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
L3V45_RS05575	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
L3V45_RS05580	COG5504	Zn-dependent protease
L3V45_RS05585	COG0444	Belongs to the ABC transporter superfamily
L3V45_RS05590	COG4608	Belongs to the ABC transporter superfamily
L3V45_RS05600	COG0601	transmembrane transport
L3V45_RS05605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L3V45_RS05615	COG0180	Tryptophanyl-tRNA synthetase
L3V45_RS05620	COG4166	transmembrane transport
L3V45_RS05625	COG0601	transmembrane transport
L3V45_RS05630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L3V45_RS05635	COG0444	Belongs to the ABC transporter superfamily
L3V45_RS05640	COG4608	Belongs to the ABC transporter superfamily
L3V45_RS05650	COG0456	acetyltransferase
L3V45_RS05655	COG1393	Belongs to the ArsC family
L3V45_RS05660	COG0861	Integral membrane protein TerC family
L3V45_RS05670	COG4862	establishment of competence for transformation
L3V45_RS05675	COG4469	Competence protein
L3V45_RS05680	COG1164	Oligoendopeptidase f
L3V45_RS05690	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
L3V45_RS05695	COG2346	COG2346, Truncated hemoglobins
L3V45_RS05700	COG0741	lytic transglycosylase activity
L3V45_RS05705	COG4116	CYTH
L3V45_RS05715	COG2357	RelA SpoT domain protein
L3V45_RS05720	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
L3V45_RS05725	COG0564	pseudouridine synthase activity
L3V45_RS05735	COG0475	glutathione-regulated potassium exporter activity
L3V45_RS05735	COG0569	domain protein
L3V45_RS05740	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L3V45_RS05745	COG0352	thiamine-phosphate diphosphorylase activity
L3V45_RS05750	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L3V45_RS05755	COG2104	thiamine diphosphate biosynthetic process
L3V45_RS05765	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
L3V45_RS05770	COG0351	phosphomethylpyrimidine kinase
L3V45_RS05775	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
L3V45_RS05830	COG0210	DNA helicase
L3V45_RS05850	COG1131	(ABC) transporter
L3V45_RS05860	COG2153	protein acetylation
L3V45_RS05870	COG2382	esterase
L3V45_RS05875	COG0626	cystathionine gamma-synthase activity
L3V45_RS05880	COG0626	cystathionine gamma-synthase activity
L3V45_RS05895	COG5444	nuclease activity
L3V45_RS05905	COG0346	lactoylglutathione lyase activity
L3V45_RS05910	COG2367	Beta-lactamase
L3V45_RS05915	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
L3V45_RS05920	COG0477	Major facilitator Superfamily
L3V45_RS05925	COG1846	Transcriptional regulator
L3V45_RS05935	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
L3V45_RS05940	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L3V45_RS05945	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
L3V45_RS05950	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
L3V45_RS05950	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
L3V45_RS05955	COG1447	Phosphotransferase system cellobiose-specific component IIA
L3V45_RS05965	COG1349	DNA-binding transcription factor activity
L3V45_RS05980	COG1846	Transcriptional regulator
L3V45_RS05985	COG1285	pathogenesis
L3V45_RS05995	COG2205	protein histidine kinase activity
L3V45_RS06005	COG3383	formate dehydrogenase (NAD+) activity
L3V45_RS06010	COG2427	Protein of unknown function (DUF1641)
L3V45_RS06015	COG2124	cytochrome p450
L3V45_RS06020	COG1819	glycosyl
L3V45_RS06030	COG1587	Uroporphyrinogen-III synthase
L3V45_RS06035	COG0390	transport system, permease component
L3V45_RS06040	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
L3V45_RS06045	COG0697	spore germination
L3V45_RS06050	COG4297	protein containing double-stranded beta helix domain
L3V45_RS06060	COG1252	NADH dehydrogenase
L3V45_RS06070	COG2211	Major facilitator Superfamily
L3V45_RS06075	COG1609	Transcriptional regulator
L3V45_RS06080	COG0246	Mannitol dehydrogenase
L3V45_RS06085	COG2721	sulfolactate sulfo-lyase activity
L3V45_RS06090	COG0745	RESPONSE REGULATOR receiver
L3V45_RS06095	COG2770	Histidine kinase
L3V45_RS06095	COG2205	protein histidine kinase activity
L3V45_RS06100	COG1121	(ABC) transporter
L3V45_RS06110	COG0730	response to heat
L3V45_RS06115	COG2318	DinB family
L3V45_RS06120	COG0457	Tetratricopeptide repeat
L3V45_RS06130	COG1388	LysM domain
L3V45_RS06130	COG3409	Peptidoglycan-binding domain 1 protein
L3V45_RS06130	COG5632	N-Acetylmuramoyl-L-alanine amidase
L3V45_RS06140	COG4195	phage-related replication protein
L3V45_RS06150	COG2856	Zn peptidase
L3V45_RS06155	COG1396	sequence-specific DNA binding
L3V45_RS06165	COG1522	sequence-specific DNA binding
L3V45_RS06170	COG1484	DNA-dependent DNA replication
L3V45_RS06190	COG1595	DNA-templated transcription, initiation
L3V45_RS06195	COG3728	DNA packaging
L3V45_RS06195	COG5484	DNA packaging
L3V45_RS06200	COG1783	phage Terminase large subunit
L3V45_RS06205	COG5518	Phage portal protein
L3V45_RS06210	COG0338	D12 class N6 adenine-specific DNA methyltransferase
L3V45_RS06215	COG4653	Phage capsid family
L3V45_RS06265	COG5412	phage tail tape measure protein
L3V45_RS06265	COG5412	phage tail tape measure protein
L3V45_RS06265	COG3953	SLT domain
L3V45_RS06265	COG3953	SLT domain
L3V45_RS06265	COG3953	SLT domain
L3V45_RS06265	COG5412	phage tail tape measure protein
L3V45_RS06270	COG1652	LysM domain
L3V45_RS06275	COG4193	domain, Protein
L3V45_RS06285	COG3628	GPW Gp25 family protein
L3V45_RS06290	COG3299	homolog of phage Mu protein gp47
L3V45_RS06295	COG3778	Protein conserved in bacteria
L3V45_RS06335	COG3409	Peptidoglycan-binding domain 1 protein
L3V45_RS06335	COG5632	N-Acetylmuramoyl-L-alanine amidase
L3V45_RS06355	COG0306	phosphate transporter
L3V45_RS06360	COG1392	Phosphate transport regulator
L3V45_RS06365	COG0531	amino acid
L3V45_RS06370	COG0346	lactoylglutathione lyase activity
L3V45_RS06375	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
L3V45_RS06380	COG0463	Glycosyl transferase, family 2
L3V45_RS06390	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L3V45_RS06395	COG0477	Major facilitator Superfamily
L3V45_RS06400	COG2362	D-Aminopeptidase
L3V45_RS06405	COG0601	transmembrane transport
L3V45_RS06410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L3V45_RS06415	COG0444	Belongs to the ABC transporter superfamily
L3V45_RS06420	COG4166	transmembrane transport
L3V45_RS06425	COG1619	proteins homologs of microcin C7 resistance protein MccF
L3V45_RS06430	COG4948	Mandelate Racemase Muconate Lactonizing
L3V45_RS06435	COG0791	NLP P60 protein
L3V45_RS06440	COG4608	Belongs to the ABC transporter superfamily
L3V45_RS06445	COG2706	6-phosphogluconolactonase activity
L3V45_RS06450	COG1834	amidinotransferase
L3V45_RS06455	COG1607	acyl-coa hydrolase
L3V45_RS06460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L3V45_RS06465	COG2076	Multidrug Resistance protein
L3V45_RS06470	COG2076	Multidrug Resistance protein
L3V45_RS06475	COG0788	formyltetrahydrofolate deformylase activity
L3V45_RS06480	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
L3V45_RS06490	COG1764	response to oxidative stress
L3V45_RS06495	COG1846	Transcriptional regulator
L3V45_RS06500	COG1764	response to oxidative stress
L3V45_RS06515	COG0463	Glycosyl transferase, family 2
L3V45_RS06515	COG0457	Tetratricopeptide repeat
L3V45_RS06525	COG2814	Major facilitator Superfamily
L3V45_RS06530	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L3V45_RS06540	COG1404	Belongs to the peptidase S8 family
L3V45_RS06545	COG1366	Belongs to the anti-sigma-factor antagonist family
L3V45_RS06550	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
L3V45_RS06555	COG1122	ATPase activity
L3V45_RS06560	COG4721	ABC-type cobalt transport system, permease component
L3V45_RS06565	COG3858	chitin binding
L3V45_RS06565	COG1388	LysM domain
L3V45_RS06575	COG2239	Acts as a magnesium transporter
L3V45_RS06580	COG0789	Transcriptional regulator
L3V45_RS06595	COG1846	Transcriptional regulator
L3V45_RS06600	COG0726	polysaccharide deacetylase
L3V45_RS06605	COG1793	dna ligase
L3V45_RS06605	COG3285	dna ligase
L3V45_RS06610	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
L3V45_RS06615	COG0586	Pfam SNARE associated Golgi protein
L3V45_RS06625	COG1191	sigma factor activity
L3V45_RS06650	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L3V45_RS06655	COG2323	membrane
L3V45_RS06665	COG3594	Acyltransferase
L3V45_RS06670	COG5002	protein histidine kinase activity
L3V45_RS06675	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L3V45_RS06695	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L3V45_RS06700	COG0436	Aminotransferase
L3V45_RS06730	COG3852	Histidine kinase
L3V45_RS06735	COG1846	Transcriptional regulator
L3V45_RS06740	COG1360	Flagellar Motor Protein
L3V45_RS06745	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
L3V45_RS06750	COG0542	response to heat
L3V45_RS06755	COG3949	Membrane
L3V45_RS06770	COG0720	synthase
L3V45_RS06775	COG0602	queuosine metabolic process
L3V45_RS06790	COG4873	Protein conserved in bacteria
L3V45_RS06800	COG3773	Cell wall hydrolase
L3V45_RS06805	COG2244	polysaccharide biosynthetic process
L3V45_RS06810	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L3V45_RS06815	COG2217	Heavy metal translocating P-type atpase
L3V45_RS06820	COG0006	proline dipeptidase activity
L3V45_RS06825	COG1609	Transcriptional regulator
L3V45_RS06830	COG3711	transcriptional antiterminator
L3V45_RS06835	COG1263	PTS System
L3V45_RS06835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L3V45_RS06835	COG2190	(PTS) system
L3V45_RS06840	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
L3V45_RS06845	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
L3V45_RS06855	COG1533	DNA photolyase activity
L3V45_RS06860	COG0840	transmembrane signaling receptor activity
L3V45_RS06865	COG2084	Dehydrogenase
L3V45_RS06870	COG2340	Cysteine-rich secretory protein family
L3V45_RS06875	COG0768	penicillin binding
L3V45_RS06880	COG4191	Histidine kinase
L3V45_RS06885	COG0436	Aminotransferase
L3V45_RS06895	COG0784	Response regulator, receiver
L3V45_RS06895	COG0835	chemotaxis
L3V45_RS06905	COG2814	Major facilitator Superfamily
L3V45_RS06910	COG1376	ErfK ybiS ycfS ynhG family protein
L3V45_RS06915	COG1408	metallophosphoesterase
L3V45_RS06920	COG1028	Short-chain dehydrogenase reductase Sdr
L3V45_RS06930	COG2200	EAL domain
L3V45_RS06935	COG4703	Protein of unknown function (DUF1797)
L3V45_RS06940	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
L3V45_RS06950	COG0517	IMP dehydrogenase activity
L3V45_RS06955	COG0583	DNA-binding transcription factor activity
L3V45_RS06960	COG0716	FMN binding
L3V45_RS06970	COG0716	FMN binding
L3V45_RS06990	COG0668	transmembrane transport
L3V45_RS06995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L3V45_RS07015	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
L3V45_RS07020	COG0303	'Molybdopterin
L3V45_RS07025	COG1763	Mo-molybdopterin cofactor biosynthetic process
L3V45_RS07030	COG0314	molybdopterin synthase activity
L3V45_RS07035	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
L3V45_RS07045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L3V45_RS07050	COG1136	(ABC) transporter
L3V45_RS07055	COG0577	efflux transmembrane transporter activity
L3V45_RS07060	COG1349	DNA-binding transcription factor activity
L3V45_RS07065	COG1105	Belongs to the carbohydrate kinase PfkB family
L3V45_RS07070	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L3V45_RS07070	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
L3V45_RS07070	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L3V45_RS07075	COG0681	Belongs to the peptidase S26 family
L3V45_RS07085	COG0488	(ABC) transporter
L3V45_RS07090	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
L3V45_RS07095	COG2309	aminopeptidase activity
L3V45_RS07105	COG1077	Cell shape determining protein MreB Mrl
L3V45_RS07110	COG2002	toxin-antitoxin pair type II binding
L3V45_RS07115	COG3852	Histidine kinase
L3V45_RS07120	COG2105	PFAM AIG2 family protein
L3V45_RS07120	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
L3V45_RS07125	COG0569	domain protein
L3V45_RS07135	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
L3V45_RS07145	COG0561	phosphatase activity
L3V45_RS07150	COG0242	peptide deformylase activity
L3V45_RS07160	COG0497	DNA recombination
L3V45_RS07170	COG1028	Short-chain dehydrogenase reductase Sdr
L3V45_RS07170	COG3321	synthase
L3V45_RS07170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L3V45_RS07170	COG4221	oxidoreductase activity
L3V45_RS07175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L3V45_RS07175	COG0300	oxidoreductase activity
L3V45_RS07175	COG3321	synthase
L3V45_RS07175	COG4221	oxidoreductase activity
L3V45_RS07180	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L3V45_RS07180	COG1028	Short-chain dehydrogenase reductase Sdr
L3V45_RS07180	COG3321	synthase
L3V45_RS07180	COG4221	oxidoreductase activity
L3V45_RS07185	COG4221	oxidoreductase activity
L3V45_RS07185	COG3321	synthase
L3V45_RS07185	COG0300	oxidoreductase activity
L3V45_RS07185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L3V45_RS07190	COG3321	synthase
L3V45_RS07190	COG0300	oxidoreductase activity
L3V45_RS07190	COG4221	oxidoreductase activity
L3V45_RS07190	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L3V45_RS07195	COG0300	oxidoreductase activity
L3V45_RS07195	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L3V45_RS07195	COG3321	synthase
L3V45_RS07195	COG4221	oxidoreductase activity
L3V45_RS07200	COG4221	oxidoreductase activity
L3V45_RS07200	COG3321	synthase
L3V45_RS07200	COG1028	Short-chain dehydrogenase reductase Sdr
L3V45_RS07200	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L3V45_RS07205	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L3V45_RS07210	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L3V45_RS07215	COG0022	dehydrogenase e1 component
L3V45_RS07220	COG0508	dehydrogenase complex catalyzes the overall conversion of
L3V45_RS07225	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L3V45_RS07230	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L3V45_RS07245	COG1982	Orn Lys Arg decarboxylase major
L3V45_RS07265	COG0483	inositol monophosphate 1-phosphatase activity
L3V45_RS07275	COG3227	Zinc metalloprotease (Elastase)
L3V45_RS07280	COG1595	DNA-templated transcription, initiation
L3V45_RS07300	COG1217	gtp-binding protein TYPA
L3V45_RS07310	COG4896	Protein conserved in bacteria
L3V45_RS07320	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
L3V45_RS07325	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
L3V45_RS07330	COG2066	Belongs to the glutaminase family
L3V45_RS07340	COG0772	Belongs to the SEDS family
L3V45_RS07345	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
L3V45_RS07360	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
L3V45_RS07360	COG2010	Cytochrome c
L3V45_RS07365	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
L3V45_RS07370	COG1845	cytochrome c oxidase, subunit III
L3V45_RS07375	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
L3V45_RS07380	COG3336	cytochrome c oxidase
L3V45_RS07390	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
L3V45_RS07395	COG2340	Cysteine-rich secretory protein family
L3V45_RS07410	COG3679	Belongs to the UPF0342 family
L3V45_RS07425	COG0742	ribosomal rna small subunit methyltransferase
L3V45_RS07435	COG3314	Sporulation integral membrane protein YlbJ
L3V45_RS07440	COG1752	Esterase of the alpha-beta hydrolase superfamily
L3V45_RS07445	COG3480	Lon protease (S16) C-terminal proteolytic domain
L3V45_RS07455	COG1399	metal-binding, possibly nucleic acid-binding protein
L3V45_RS07475	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
L3V45_RS07495	COG4839	cell division protein FtsL
L3V45_RS07500	COG0768	penicillin binding
L3V45_RS07505	COG0768	penicillin binding
L3V45_RS07525	COG0772	Belongs to the SEDS family
L3V45_RS07540	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
L3V45_RS07545	COG0849	cell division
L3V45_RS07550	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
L3V45_RS07555	COG4412	M6 family metalloprotease domain protein
L3V45_RS07555	COG1404	Belongs to the peptidase S8 family
L3V45_RS07565	COG1191	sigma factor activity
L3V45_RS07570	COG1191	sigma factor activity
L3V45_RS07575	COG1119	ATPase activity
L3V45_RS07580	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
L3V45_RS07585	COG1873	PFAM PRC-barrel domain
L3V45_RS07590	COG1496	oxidoreductase activity
L3V45_RS07595	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
L3V45_RS07605	COG0762	integral membrane protein
L3V45_RS07610	COG2302	S4 RNA-binding domain
L3V45_RS07615	COG3599	regulation of cell shape
L3V45_RS07620	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
L3V45_RS07625	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
L3V45_RS07635	COG0564	pseudouridine synthase activity
L3V45_RS07645	COG2233	PERMEase
L3V45_RS07655	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
L3V45_RS07660	COG0505	Belongs to the CarA family
L3V45_RS07665	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
L3V45_RS07680	COG0284	orotidine-5'-phosphate decarboxylase activity
L3V45_RS07685	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
L3V45_RS07695	COG0306	phosphate transporter
L3V45_RS07710	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
L3V45_RS07715	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
L3V45_RS07720	COG1648	precorrin-2 dehydrogenase activity
L3V45_RS07730	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
L3V45_RS07735	COG1561	YicC-like family, N-terminal region
L3V45_RS07745	COG0194	GDP metabolic process
L3V45_RS07755	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
L3V45_RS07760	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
L3V45_RS07765	COG0242	peptide deformylase activity
L3V45_RS07775	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
L3V45_RS07775	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
L3V45_RS07785	COG0631	protein serine/threonine phosphatase activity
L3V45_RS07790	COG0515	serine threonine protein kinase
L3V45_RS07790	COG2815	serine threonine protein kinase
L3V45_RS07800	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
L3V45_RS07805	COG1564	THIamine pyrophosphokinase
L3V45_RS07820	COG1302	Protein conserved in bacteria
L3V45_RS07825	COG1461	Dihydroxyacetone kinase
L3V45_RS07830	COG1760	l-serine dehydratase
L3V45_RS07835	COG1760	l-serine dehydratase
L3V45_RS07840	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
L3V45_RS07855	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
L3V45_RS07860	COG1028	Short-chain dehydrogenase reductase Sdr
L3V45_RS07875	COG1196	nuclear chromosome segregation
L3V45_RS07880	COG0552	protein localization to endoplasmic reticulum
L3V45_RS07895	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
L3V45_RS07905	COG1837	Belongs to the UPF0109 family
L3V45_RS07930	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
L3V45_RS07945	COG2257	FlhB HrpN YscU SpaS Family
L3V45_RS07955	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
L3V45_RS07960	COG0758	DNA mediated transformation
L3V45_RS07965	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
L3V45_RS07975	COG4974	Belongs to the 'phage' integrase family
L3V45_RS07995	COG1815	bacterial-type flagellum-dependent cell motility
L3V45_RS08000	COG1558	bacterial-type flagellum-dependent cell motility
L3V45_RS08005	COG1677	Flagellar hook-basal body complex protein FliE
L3V45_RS08010	COG1766	The M ring may be actively involved in energy transduction
L3V45_RS08015	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
L3V45_RS08020	COG1317	bacterial-type flagellum organization
L3V45_RS08025	COG1157	protein secretion by the type III secretion system
L3V45_RS08030	COG2882	bacterial-type flagellum organization
L3V45_RS08035	COG3334	PFAM MgtE intracellular
L3V45_RS08040	COG3144	bacterial-type flagellum assembly
L3V45_RS08045	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
L3V45_RS08050	COG4786	Flagellar basal body rod
L3V45_RS08055	COG1582	Flagellar protein (FlbD)
L3V45_RS08060	COG1580	Controls the rotational direction of flagella during chemotaxis
L3V45_RS08065	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
L3V45_RS08070	COG1776	CheC inhibitor of MCP methylation
L3V45_RS08070	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
L3V45_RS08075	COG2201	protein-glutamate methylesterase activity
L3V45_RS08080	COG3190	flagellar
L3V45_RS08085	COG1338	Plays a role in the flagellum-specific transport system
L3V45_RS08090	COG1987	bacterial-type flagellum assembly
L3V45_RS08095	COG1684	flagellar biosynthetic protein fliR
L3V45_RS08100	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
L3V45_RS08105	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
L3V45_RS08110	COG1419	protein localization to endoplasmic reticulum
L3V45_RS08115	COG0455	bacterial-type flagellum organization
L3V45_RS08120	COG2201	protein-glutamate methylesterase activity
L3V45_RS08125	COG0643	Histidine kinase
L3V45_RS08125	COG2198	Histidine kinase
L3V45_RS08130	COG0835	chemotaxis
L3V45_RS08135	COG1776	CheC inhibitor of MCP methylation
L3V45_RS08145	COG1191	sigma factor activity
L3V45_RS08175	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
L3V45_RS08180	COG4589	Belongs to the CDS family
L3V45_RS08190	COG0750	zinc metalloprotease
L3V45_RS08210	COG0195	Participates in both transcription termination and antitermination
L3V45_RS08215	COG2740	Nucleic-acid-binding protein implicated in transcription termination
L3V45_RS08220	COG1358	cellular component organization or biogenesis
L3V45_RS08230	COG1550	Protein conserved in bacteria
L3V45_RS08245	COG0196	riboflavin kinase activity
L3V45_RS08260	COG0726	polysaccharide deacetylase
L3V45_RS08265	COG0612	Peptidase, M16
L3V45_RS08270	COG1873	PFAM PRC-barrel domain
L3V45_RS08275	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
L3V45_RS08280	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
L3V45_RS08285	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
L3V45_RS08290	COG0527	aspartate kinase activity
L3V45_RS08300	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
L3V45_RS08305	COG0740	serine-type endopeptidase activity
L3V45_RS08315	COG1674	ftsk spoiiie
L3V45_RS08315	COG4980	gas vesicle protein
L3V45_RS08320	COG2188	Transcriptional regulator
L3V45_RS08325	COG2814	Major facilitator Superfamily
L3V45_RS08330	COG1846	Transcriptional regulator
L3V45_RS08335	COG2409	Drug exporters of the RND superfamily
L3V45_RS08335	COG1033	growth of symbiont in host cell
L3V45_RS08340	COG0612	Peptidase, M16
L3V45_RS08345	COG0612	Peptidase, M16
L3V45_RS08350	COG0300	oxidoreductase activity
L3V45_RS08365	COG1426	Protein conserved in bacteria
L3V45_RS08370	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
L3V45_RS08385	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L3V45_RS08395	COG1692	metallophosphoesterase
L3V45_RS08400	COG2359	stage V sporulation protein S
L3V45_RS08420	COG4550	Control of competence regulator ComK, YlbF/YmcA
L3V45_RS08465	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L3V45_RS08470	COG3425	synthase
L3V45_RS08475	COG1024	Enoyl-CoA hydratase
L3V45_RS08480	COG1024	Enoyl-CoA hydratase
L3V45_RS08485	COG0300	oxidoreductase activity
L3V45_RS08485	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L3V45_RS08485	COG1028	Short-chain dehydrogenase reductase Sdr
L3V45_RS08485	COG0318	PFAM AMP-dependent synthetase and ligase
L3V45_RS08485	COG3321	synthase
L3V45_RS08490	COG3321	synthase
L3V45_RS08490	COG0300	oxidoreductase activity
L3V45_RS08490	COG4221	oxidoreductase activity
L3V45_RS08490	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L3V45_RS08495	COG1028	Short-chain dehydrogenase reductase Sdr
L3V45_RS08495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L3V45_RS08495	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L3V45_RS08495	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L3V45_RS08495	COG3321	synthase
L3V45_RS08495	COG1028	Short-chain dehydrogenase reductase Sdr
L3V45_RS08495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L3V45_RS08495	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L3V45_RS08495	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L3V45_RS08495	COG3321	synthase
L3V45_RS08500	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L3V45_RS08500	COG1028	Short-chain dehydrogenase reductase Sdr
L3V45_RS08500	COG3321	synthase
L3V45_RS08500	COG4221	oxidoreductase activity
L3V45_RS08505	COG3321	synthase
L3V45_RS08505	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
L3V45_RS08505	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L3V45_RS08505	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
L3V45_RS08510	COG2124	cytochrome p450
L3V45_RS08515	COG3209	COG3209 Rhs family protein
L3V45_RS08520	COG3619	membrane
L3V45_RS08530	COG1404	Belongs to the peptidase S8 family
L3V45_RS08540	COG4195	phage-related replication protein
L3V45_RS08545	COG1764	response to oxidative stress
L3V45_RS08555	COG2076	Multidrug Resistance protein
L3V45_RS08595	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L3V45_RS08600	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L3V45_RS08605	COG4112	unkown
L3V45_RS08610	COG0860	N-Acetylmuramoyl-L-alanine amidase
L3V45_RS08615	COG0464	growth
L3V45_RS08620	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
L3V45_RS08625	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
L3V45_RS08630	COG0789	Transcriptional regulator
L3V45_RS08635	COG0174	glutamine synthetase
L3V45_RS08645	COG2211	Major facilitator Superfamily
L3V45_RS08665	COG1070	Carbohydrate kinase
L3V45_RS08670	COG3848	Pyruvate phosphate dikinase
L3V45_RS08670	COG0574	Belongs to the PEP-utilizing enzyme family
L3V45_RS08690	COG1064	alcohol dehydrogenase
L3V45_RS08700	COG0456	acetyltransferase
L3V45_RS08720	COG3397	chitin binding
L3V45_RS08740	COG5434	Belongs to the glycosyl hydrolase 28 family
L3V45_RS08745	COG0756	dUTP diphosphatase activity
L3V45_RS08750	COG4195	phage-related replication protein
L3V45_RS08785	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
L3V45_RS08795	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
L3V45_RS08815	COG0785	Cytochrome C biogenesis protein
L3V45_RS08820	COG2201	protein-glutamate methylesterase activity
L3V45_RS08825	COG4846	Membrane protein involved in cytochrome C biogenesis
L3V45_RS08835	COG0071	Belongs to the small heat shock protein (HSP20) family
L3V45_RS08850	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
L3V45_RS08855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L3V45_RS08875	COG0824	Thioesterase
L3V45_RS08885	COG4841	protein insertion into membrane
L3V45_RS08895	COG1832	CoA-binding protein
L3V45_RS08900	COG0187	DNA topoisomerase II activity
L3V45_RS08905	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
L3V45_RS08915	COG1115	amino acid carrier protein
L3V45_RS08925	COG1063	alcohol dehydrogenase
L3V45_RS08930	COG0800	Aldolase
L3V45_RS08935	COG1312	Catalyzes the dehydration of D-mannonate
L3V45_RS08940	COG1028	Short-chain dehydrogenase reductase Sdr
L3V45_RS08945	COG1609	Transcriptional regulator
L3V45_RS08950	COG2271	Major facilitator Superfamily
L3V45_RS08985	COG2205	protein histidine kinase activity
L3V45_RS08990	COG0745	RESPONSE REGULATOR receiver
L3V45_RS09000	COG3507	Belongs to the glycosyl hydrolase 43 family
L3V45_RS09025	COG1028	Short-chain dehydrogenase reductase Sdr
L3V45_RS09030	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L3V45_RS09035	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L3V45_RS09040	COG2610	gluconate transmembrane transporter activity
L3V45_RS09045	COG2124	cytochrome p450
L3V45_RS09065	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
L3V45_RS09075	COG2246	polysaccharide biosynthetic process
L3V45_RS09080	COG1210	Utp--glucose-1-phosphate uridylyltransferase
L3V45_RS09085	COG0586	Pfam SNARE associated Golgi protein
L3V45_RS09090	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L3V45_RS09095	COG1024	Enoyl-CoA hydratase
L3V45_RS09100	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
L3V45_RS09105	COG0511	ligase activity, forming carbon-carbon bonds
L3V45_RS09110	COG0439	Biotin carboxylase
L3V45_RS09115	COG0318	PFAM AMP-dependent synthetase and ligase
L3V45_RS09120	COG1960	acyl-CoA dehydrogenase activity
L3V45_RS09125	COG1649	PFAM Uncharacterised BCR, COG1649
L3V45_RS09135	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L3V45_RS09135	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
L3V45_RS09140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L3V45_RS09145	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L3V45_RS09150	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L3V45_RS09155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L3V45_RS09160	COG2027	D-alanyl-D-alanine carboxypeptidase
L3V45_RS09165	COG2017	converts alpha-aldose to the beta-anomer
L3V45_RS09170	COG0534	Mate efflux family protein
L3V45_RS09180	COG5444	nuclease activity
L3V45_RS09200	COG3409	Peptidoglycan-binding domain 1 protein
L3V45_RS09200	COG5632	N-Acetylmuramoyl-L-alanine amidase
L3V45_RS09205	COG4824	toxin secretion phage lysis holin
L3V45_RS09220	COG5434	Belongs to the glycosyl hydrolase 28 family
L3V45_RS09300	COG1802	Transcriptional regulator
L3V45_RS09300	COG4626	Terminase
L3V45_RS09320	COG0582	viral genome integration into host DNA
L3V45_RS09325	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
L3V45_RS09450	COG0582	viral genome integration into host DNA
L3V45_RS09455	COG0166	Belongs to the GPI family
L3V45_RS09460	COG0405	Gamma-glutamyltransferase
L3V45_RS09465	COG2814	Major facilitator Superfamily
L3V45_RS09470	COG0640	Transcriptional regulator
L3V45_RS09480	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
L3V45_RS09490	COG0604	alcohol dehydrogenase
L3V45_RS09495	COG0493	'glutamate synthase
L3V45_RS09500	COG0067	glutamate synthase
L3V45_RS09500	COG0069	glutamate synthase activity
L3V45_RS09500	COG0070	glutamate synthase
L3V45_RS09505	COG0583	DNA-binding transcription factor activity
L3V45_RS09510	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
L3V45_RS09525	COG0300	oxidoreductase activity
L3V45_RS09530	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
L3V45_RS09540	COG2814	Major facilitator Superfamily
L3V45_RS09545	COG1070	Carbohydrate kinase
L3V45_RS09550	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
L3V45_RS09555	COG0243	molybdopterin cofactor binding
L3V45_RS09575	COG1028	Short-chain dehydrogenase reductase Sdr
L3V45_RS09580	COG1733	regulation of RNA biosynthetic process
L3V45_RS09585	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L3V45_RS09590	COG0662	Cupin 2, conserved barrel domain protein
L3V45_RS09590	COG2207	Transcriptional regulator
L3V45_RS09595	COG1309	transcriptional regulator
L3V45_RS09600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L3V45_RS09610	COG0640	Transcriptional regulator
L3V45_RS09615	COG0741	lytic transglycosylase activity
L3V45_RS09620	COG2322	membrane
L3V45_RS09635	COG1619	proteins homologs of microcin C7 resistance protein MccF
L3V45_RS09645	COG1388	LysM domain
L3V45_RS09645	COG3584	3D domain protein
L3V45_RS09650	COG0514	ATP-dependent DNA helicase (RecQ)
L3V45_RS09660	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
L3V45_RS09665	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
L3V45_RS09680	COG0071	Belongs to the small heat shock protein (HSP20) family
L3V45_RS09710	COG1012	belongs to the aldehyde dehydrogenase family
L3V45_RS09715	COG1657	PFAM Prenyltransferase squalene oxidase
L3V45_RS09720	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
L3V45_RS09725	COG0733	neurotransmitter:sodium symporter activity
L3V45_RS09730	COG0385	Bile acid
L3V45_RS09735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L3V45_RS09740	COG0508	dehydrogenase complex catalyzes the overall conversion of
L3V45_RS09750	COG4548	von Willebrand factor, type A
L3V45_RS09755	COG0714	Associated with various cellular activities
L3V45_RS09760	COG2032	superoxide dismutase activity
L3V45_RS09765	COG1388	LysM domain
L3V45_RS09765	COG0791	NLP P60 protein
L3V45_RS09770	COG1819	glycosyl
L3V45_RS09775	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
L3V45_RS09780	COG0534	Mate efflux family protein
L3V45_RS09785	COG1366	Belongs to the anti-sigma-factor antagonist family
L3V45_RS09790	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
L3V45_RS09795	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
L3V45_RS09805	COG2962	Rard protein
L3V45_RS09820	COG1942	4-Oxalocrotonate Tautomerase
L3V45_RS09830	COG1733	regulation of RNA biosynthetic process
L3V45_RS09835	COG0778	Nitroreductase
L3V45_RS09840	COG0400	carboxylic ester hydrolase activity
L3V45_RS09845	COG0346	lactoylglutathione lyase activity
L3V45_RS09855	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L3V45_RS09865	COG2723	6-phospho-beta-galactosidase activity
L3V45_RS09870	COG2188	Transcriptional regulator
L3V45_RS09875	COG3409	Peptidoglycan-binding domain 1 protein
L3V45_RS09875	COG0793	Belongs to the peptidase S41A family
L3V45_RS09880	COG2226	methyltransferase
L3V45_RS09890	COG1876	peptidase activity
L3V45_RS09910	COG0671	phosphoesterase, PA-phosphatase related
L3V45_RS09945	COG1509	lysine 2,3-aminomutase activity
L3V45_RS09950	COG0456	acetyltransferase
L3V45_RS09955	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
L3V45_RS09960	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L3V45_RS09965	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L3V45_RS09970	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
L3V45_RS09975	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
L3V45_RS09985	COG0456	acetyltransferase
L3V45_RS09990	COG0463	Glycosyl transferase, family 2
L3V45_RS10005	COG4641	Protein conserved in bacteria
L3V45_RS10015	COG1086	Polysaccharide biosynthesis protein
L3V45_RS10065	COG1388	LysM domain
L3V45_RS10070	COG0457	Tetratricopeptide repeat
L3V45_RS10080	COG3391	amine dehydrogenase activity
L3V45_RS10125	COG5444	nuclease activity
L3V45_RS10130	COG4282	regulation of fungal-type cell wall biogenesis
L3V45_RS10165	COG1846	Transcriptional regulator
L3V45_RS10170	COG4698	Protein conserved in bacteria
L3V45_RS10175	COG2755	lipolytic protein G-D-S-L family
L3V45_RS10180	COG1999	signal sequence binding
L3V45_RS10190	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L3V45_RS10195	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
L3V45_RS10200	COG1272	protein, Hemolysin III
L3V45_RS10205	COG0204	Acyl-transferase
L3V45_RS10210	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
L3V45_RS10225	COG2521	methyltransferase
L3V45_RS10225	COG2136	Putative SAM-dependent methyltransferase
L3V45_RS10240	COG1413	lyase activity
L3V45_RS10245	COG1418	mRNA catabolic process
L3V45_RS10250	COG0386	Belongs to the glutathione peroxidase family
L3V45_RS10260	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
L3V45_RS10270	COG1278	Cold shock
L3V45_RS10290	COG0328	RNA-DNA hybrid ribonuclease activity
L3V45_RS10295	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
L3V45_RS10300	COG0328	RNA-DNA hybrid ribonuclease activity
L3V45_RS10310	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
L3V45_RS10325	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
L3V45_RS10335	COG1755	Isoprenylcysteine carboxyl methyltransferase
L3V45_RS10340	COG3424	synthase
L3V45_RS10365	COG1335	isochorismatase
L3V45_RS10410	COG4824	toxin secretion phage lysis holin
L3V45_RS10430	COG5434	Belongs to the glycosyl hydrolase 28 family
L3V45_RS10435	COG1705	Flagellar rod assembly protein muramidase FlgJ
L3V45_RS10445	COG5280	Phage tail tape measure protein TP901
L3V45_RS10445	COG3953	SLT domain
L3V45_RS10550	COG1595	DNA-templated transcription, initiation
L3V45_RS10590	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
L3V45_RS10600	COG1484	DNA-dependent DNA replication
L3V45_RS10605	COG3935	DnaD domain protein
L3V45_RS10640	COG3645	SOS response
L3V45_RS10640	COG3646	Phage regulatory protein
L3V45_RS10655	COG3620	sequence-specific DNA binding
L3V45_RS10660	COG0582	viral genome integration into host DNA
L3V45_RS10665	COG2233	PERMEase
L3V45_RS10675	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
L3V45_RS10680	COG1199	ATP-dependent helicase activity
L3V45_RS10695	COG0116	Belongs to the methyltransferase superfamily
L3V45_RS10725	COG3359	exonuclease
L3V45_RS10730	COG1111	helicase
L3V45_RS10730	COG1205	dead DEAH box helicase
L3V45_RS10735	COG2190	(PTS) system
L3V45_RS10740	COG0071	Belongs to the small heat shock protein (HSP20) family
L3V45_RS10780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L3V45_RS10780	COG4499	WXG100 protein secretion system (Wss), protein YukC
L3V45_RS10790	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
L3V45_RS10795	COG3935	DnaD domain protein
L3V45_RS10805	COG0436	Aminotransferase
L3V45_RS10810	COG5353	protein conserved in bacteria
L3V45_RS10820	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L3V45_RS10820	COG1199	ATP-dependent helicase activity
L3V45_RS10850	COG0438	transferase activity, transferring glycosyl groups
L3V45_RS10855	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
L3V45_RS10870	COG1694	Mazg nucleotide pyrophosphohydrolase
L3V45_RS10875	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L3V45_RS10880	COG2140	Oxalate decarboxylase
L3V45_RS10890	COG4347	Protein of unknown function (DUF1405)
L3V45_RS10895	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
L3V45_RS10895	COG2010	Cytochrome c
L3V45_RS10900	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
L3V45_RS10905	COG0723	plastoquinol--plastocyanin reductase activity
L3V45_RS10920	COG0457	Tetratricopeptide repeat
L3V45_RS10930	COG0287	Prephenate dehydrogenase
L3V45_RS10965	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
L3V45_RS10970	COG4401	Chorismate mutase type I
L3V45_RS10985	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
L3V45_RS10990	COG0105	UTP biosynthetic process
L3V45_RS10995	COG0142	geranyltranstransferase activity
L3V45_RS11005	COG0142	geranyltranstransferase activity
L3V45_RS11020	COG0776	regulation of translation
L3V45_RS11025	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
L3V45_RS11065	COG0539	negative regulation of cytoplasmic translation
L3V45_RS11080	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
L3V45_RS11085	COG2959	enzyme of heme biosynthesis
L3V45_RS11090	COG3409	Peptidoglycan-binding domain 1 protein
L3V45_RS11090	COG3773	Cell wall hydrolase
L3V45_RS11095	COG2339	peptidase activity
L3V45_RS11100	COG0492	ferredoxin-NADP+ reductase activity
L3V45_RS11105	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L3V45_RS11110	COG4862	establishment of competence for transformation
L3V45_RS11115	COG1408	metallophosphoesterase
L3V45_RS11125	COG1388	LysM domain
L3V45_RS11130	COG1266	CAAX protease self-immunity
L3V45_RS11135	COG0514	ATP-dependent DNA helicase (RecQ)
L3V45_RS11140	COG4955	Helix-turn-helix domain
L3V45_RS11145	COG1141	Ferredoxin
L3V45_RS11150	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
L3V45_RS11155	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
L3V45_RS11165	COG1595	DNA-templated transcription, initiation
L3V45_RS11170	COG5002	protein histidine kinase activity
L3V45_RS11175	COG0745	RESPONSE REGULATOR receiver
L3V45_RS11180	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
L3V45_RS11185	COG1333	cytochrome c biogenesis protein
L3V45_RS11190	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L3V45_RS11195	COG1187	pseudouridine synthase activity
L3V45_RS11200	COG0700	Nucleoside recognition
L3V45_RS11205	COG2715	membrane protein required for spore maturation
L3V45_RS11210	COG1686	Belongs to the peptidase S11 family
L3V45_RS11235	COG1547	Domain of unknown function (DUF309)
L3V45_RS11240	COG0456	acetyltransferase
L3V45_RS11255	COG0307	riboflavin synthase, alpha
L3V45_RS11260	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L3V45_RS11260	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L3V45_RS11270	COG0681	Belongs to the peptidase S26 family
L3V45_RS11280	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
L3V45_RS11285	COG4086	secreted protein
L3V45_RS11290	COG0019	diaminopimelate decarboxylase activity
L3V45_RS11295	COG0697	spore germination
L3V45_RS11310	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
L3V45_RS11330	COG1191	sigma factor activity
L3V45_RS11340	COG1366	Belongs to the anti-sigma-factor antagonist family
L3V45_RS11345	COG1686	Belongs to the peptidase S11 family
L3V45_RS11350	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
L3V45_RS11355	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
L3V45_RS11360	COG4974	Belongs to the 'phage' integrase family
L3V45_RS11370	COG0735	belongs to the Fur family
L3V45_RS11375	COG1300	Membrane
L3V45_RS11390	COG0281	malic enzyme
L3V45_RS11395	COG1757	Na H antiporter
L3V45_RS11400	COG1027	Aspartate ammonia-lyase
L3V45_RS11405	COG0252	asparaginase activity
L3V45_RS11410	COG1396	sequence-specific DNA binding
L3V45_RS11415	COG1379	DNA repair
L3V45_RS11420	COG0494	nUDIX hydrolase
L3V45_RS11430	COG0667	Aldo Keto reductase
L3V45_RS11440	COG1073	alpha beta
L3V45_RS11450	COG4918	Iron-sulphur cluster biosynthesis
L3V45_RS11455	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
L3V45_RS11455	COG0456	acetyltransferase
L3V45_RS11460	COG2329	Antibiotic biosynthesis monooxygenase
L3V45_RS11465	COG0456	acetyltransferase
L3V45_RS11470	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
L3V45_RS11485	COG0628	permease
L3V45_RS11495	COG0346	lactoylglutathione lyase activity
L3V45_RS11505	COG3048	D-serine ammonia-lyase activity
L3V45_RS11510	COG0300	oxidoreductase activity
L3V45_RS11515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L3V45_RS11520	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
L3V45_RS11525	COG1024	Enoyl-CoA hydratase
L3V45_RS11530	COG3425	synthase
L3V45_RS11535	COG2124	cytochrome p450
L3V45_RS11540	COG3321	synthase
L3V45_RS11540	COG1028	Short-chain dehydrogenase reductase Sdr
L3V45_RS11540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L3V45_RS11540	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L3V45_RS11540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L3V45_RS11545	COG3321	synthase
L3V45_RS11545	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L3V45_RS11545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L3V45_RS11545	COG1028	Short-chain dehydrogenase reductase Sdr
L3V45_RS11545	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L3V45_RS11550	COG0318	PFAM AMP-dependent synthetase and ligase
L3V45_RS11550	COG0300	oxidoreductase activity
L3V45_RS11550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L3V45_RS11550	COG1028	Short-chain dehydrogenase reductase Sdr
L3V45_RS11550	COG3321	synthase
L3V45_RS11555	COG0300	oxidoreductase activity
L3V45_RS11555	COG3321	synthase
L3V45_RS11555	COG1028	Short-chain dehydrogenase reductase Sdr
L3V45_RS11555	COG0318	PFAM AMP-dependent synthetase and ligase
L3V45_RS11555	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L3V45_RS11560	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L3V45_RS11560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L3V45_RS11560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L3V45_RS11560	COG3321	synthase
L3V45_RS11560	COG1028	Short-chain dehydrogenase reductase Sdr
L3V45_RS11565	COG0300	oxidoreductase activity
L3V45_RS11565	COG3321	synthase
L3V45_RS11565	COG1028	Short-chain dehydrogenase reductase Sdr
L3V45_RS11565	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L3V45_RS11565	COG0318	PFAM AMP-dependent synthetase and ligase
L3V45_RS11570	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L3V45_RS11570	COG1028	Short-chain dehydrogenase reductase Sdr
L3V45_RS11570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L3V45_RS11570	COG3321	synthase
L3V45_RS11570	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L3V45_RS11575	COG1028	Short-chain dehydrogenase reductase Sdr
L3V45_RS11580	COG0318	PFAM AMP-dependent synthetase and ligase
L3V45_RS11595	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
L3V45_RS11595	COG2070	2-Nitropropane dioxygenase
L3V45_RS11600	COG0250	Participates in transcription elongation, termination and antitermination
L3V45_RS11620	COG0596	Alpha beta hydrolase
L3V45_RS11635	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
L3V45_RS11640	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
L3V45_RS11655	COG0706	membrane insertase activity
L3V45_RS11660	COG2195	Cleaves the N-terminal amino acid of tripeptides
L3V45_RS11665	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L3V45_RS11670	COG0346	lactoylglutathione lyase activity
L3V45_RS11680	COG1376	ErfK ybiS ycfS ynhG family protein
L3V45_RS11685	COG4129	membrane
L3V45_RS11690	COG1126	abc transporter atp-binding protein
L3V45_RS11695	COG0765	amino acid transport
L3V45_RS11700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L3V45_RS11710	COG1597	lipid kinase activity
L3V45_RS11715	COG0508	dehydrogenase complex catalyzes the overall conversion of
L3V45_RS11720	COG0022	dehydrogenase e1 component
L3V45_RS11725	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L3V45_RS11730	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L3V45_RS11735	COG3426	butyrate kinase activity
L3V45_RS11740	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L3V45_RS11745	COG0280	phosphate acetyltransferase
L3V45_RS11750	COG3290	protein histidine kinase activity
L3V45_RS11750	COG3829	transcription factor binding
L3V45_RS11760	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
L3V45_RS11765	COG2079	MmgE PrpD family protein
L3V45_RS11770	COG0372	Belongs to the citrate synthase family
L3V45_RS11775	COG1960	acyl-CoA dehydrogenase activity
L3V45_RS11780	COG1250	3-hydroxyacyl-CoA dehydrogenase
L3V45_RS11785	COG0183	Belongs to the thiolase family
L3V45_RS11790	COG0584	glycerophosphoryl diester phosphodiesterase
L3V45_RS11795	COG0860	N-Acetylmuramoyl-L-alanine amidase
L3V45_RS11820	COG1902	pentaerythritol trinitrate reductase activity
L3V45_RS11835	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
L3V45_RS11840	COG0745	RESPONSE REGULATOR receiver
L3V45_RS11845	COG0750	zinc metalloprotease
L3V45_RS11850	COG0497	DNA recombination
L3V45_RS11860	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
L3V45_RS11870	COG0142	geranyltranstransferase activity
L3V45_RS11880	COG1570	exodeoxyribonuclease VII activity
L3V45_RS11895	COG1302	Protein conserved in bacteria
L3V45_RS11900	COG0439	Biotin carboxylase
L3V45_RS11905	COG0511	ligase activity, forming carbon-carbon bonds
L3V45_RS11945	COG3854	ATPases associated with a variety of cellular activities
L3V45_RS11960	COG0006	proline dipeptidase activity
L3V45_RS11970	COG3872	metal-dependent enzyme
L3V45_RS11980	COG1752	Esterase of the alpha-beta hydrolase superfamily
L3V45_RS11995	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
L3V45_RS12015	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
L3V45_RS12030	COG1396	sequence-specific DNA binding
L3V45_RS12040	COG0681	Belongs to the peptidase S26 family
L3V45_RS12065	COG4940	Competence protein ComGF
L3V45_RS12075	COG4970	Tfp pilus assembly protein FimT
L3V45_RS12080	COG4537	Required for transformation and DNA binding
L3V45_RS12085	COG1459	type II secretion system
L3V45_RS12090	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
L3V45_RS12095	COG0598	Magnesium transport protein CorA
L3V45_RS12100	COG1253	flavin adenine dinucleotide binding
L3V45_RS12105	COG1366	Belongs to the anti-sigma-factor antagonist family
L3V45_RS12115	COG1393	Belongs to the ArsC family
L3V45_RS12125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L3V45_RS12135	COG0011	TIGRFAM Protein of
L3V45_RS12145	COG2866	Carboxypeptidase
L3V45_RS12150	COG1940	carbohydrate kinase activity
L3V45_RS12155	COG4483	Protein conserved in bacteria
L3V45_RS12160	COG1757	Na H antiporter
L3V45_RS12170	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
L3V45_RS12185	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
L3V45_RS12190	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
L3V45_RS12195	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
L3V45_RS12200	COG0581	inorganic phosphate transmembrane transporter activity
L3V45_RS12205	COG0573	inorganic phosphate transmembrane transporter activity
L3V45_RS12210	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
L3V45_RS12215	COG0768	penicillin binding
L3V45_RS12220	COG0477	Major facilitator Superfamily
L3V45_RS12225	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
L3V45_RS12230	COG2839	Protein conserved in bacteria
L3V45_RS12235	COG5521	maltodextrose utilization protein MalA
L3V45_RS12240	COG1388	LysM domain
L3V45_RS12250	COG4709	membrane
L3V45_RS12255	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
L3V45_RS12260	COG0735	belongs to the Fur family
L3V45_RS12265	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L3V45_RS12280	COG0513	Belongs to the DEAD box helicase family
L3V45_RS12295	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
L3V45_RS12300	COG2384	SAM-dependent methyltransferase
L3V45_RS12305	COG2010	Cytochrome c
L3V45_RS12310	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
L3V45_RS12315	COG0358	DNA primase activity
L3V45_RS12330	COG0517	IMP dehydrogenase activity
L3V45_RS12335	COG0751	glycine-tRNA ligase activity
L3V45_RS12355	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
L3V45_RS12360	COG0295	cytidine deaminase activity
L3V45_RS12365	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
L3V45_RS12375	COG1480	7TM receptor with intracellular HD hydrolase
L3V45_RS12380	COG1702	phosphate starvation-inducible protein PhoH
L3V45_RS12385	COG0561	phosphatase activity
L3V45_RS12400	COG4864	UPF0365 protein
L3V45_RS12405	COG1030	water channel activity
L3V45_RS12410	COG1610	YqeY-like protein
L3V45_RS12420	COG1283	sodium-dependent phosphate transmembrane transporter activity
L3V45_RS12425	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
L3V45_RS12430	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L3V45_RS12460	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L3V45_RS12475	COG0860	N-Acetylmuramoyl-L-alanine amidase
L3V45_RS12505	COG0658	competence protein
L3V45_RS12505	COG2333	competence protein COMEC
L3V45_RS12510	COG2131	deaminase
L3V45_RS12515	COG1555	photosystem II stabilization
L3V45_RS12515	COG1596	polysaccharide export
L3V45_RS12520	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
L3V45_RS12525	COG2226	methyltransferase
L3V45_RS12530	COG0799	negative regulation of ribosome biogenesis
L3V45_RS12535	COG1713	HD superfamily hydrolase involved in NAD metabolism
L3V45_RS12545	COG1534	Rna-binding protein
L3V45_RS12550	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
L3V45_RS12555	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
L3V45_RS12560	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
L3V45_RS12570	COG2755	lipolytic protein G-D-S-L family
L3V45_RS12580	COG0398	Pfam SNARE associated Golgi protein
L3V45_RS12605	COG2207	Transcriptional regulator
L3V45_RS12605	COG3708	Transcriptional regulator
L3V45_RS12610	COG0563	adenylate kinase activity
L3V45_RS12615	COG2814	Major facilitator Superfamily
L3V45_RS12620	COG0456	acetyltransferase
L3V45_RS12625	COG2318	DinB family
L3V45_RS12635	COG0561	phosphatase activity
L3V45_RS12640	COG0561	phosphatase activity
L3V45_RS12650	COG1482	cell wall glycoprotein biosynthetic process
L3V45_RS12655	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L3V45_RS12655	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L3V45_RS12655	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
L3V45_RS12660	COG3711	transcriptional antiterminator
L3V45_RS12660	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
L3V45_RS12670	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
L3V45_RS12675	COG0583	DNA-binding transcription factor activity
L3V45_RS12680	COG2814	Major facilitator Superfamily
L3V45_RS12685	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
L3V45_RS12685	COG2124	cytochrome p450
L3V45_RS12690	COG1309	transcriptional regulator
L3V45_RS12695	COG2226	methyltransferase
L3V45_RS12710	COG2116	formate transmembrane transporter activity
L3V45_RS12715	COG5609	conserved protein (DUF2294)
L3V45_RS12720	COG3383	formate dehydrogenase (NAD+) activity
L3V45_RS12725	COG2427	Protein of unknown function (DUF1641)
L3V45_RS12735	COG0626	cystathionine gamma-synthase activity
L3V45_RS12740	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L3V45_RS12765	COG0768	penicillin binding
L3V45_RS12780	COG0826	peptidase U32
L3V45_RS12785	COG0826	peptidase U32
L3V45_RS12790	COG4122	O-methyltransferase activity
L3V45_RS12795	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
L3V45_RS12810	COG4472	Bacterial protein of unknown function (DUF965)
L3V45_RS12820	COG0628	permease
L3V45_RS12825	COG1126	abc transporter atp-binding protein
L3V45_RS12830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L3V45_RS12835	COG0765	amino acid transport
L3V45_RS12840	COG0765	amino acid transport
L3V45_RS12855	COG3881	PFAM PRC-barrel domain
L3V45_RS12860	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L3V45_RS12865	COG0457	Tetratricopeptide repeat
L3V45_RS12875	COG1104	cysteine desulfurase activity
L3V45_RS12880	COG1959	2 iron, 2 sulfur cluster binding
L3V45_RS12885	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
L3V45_RS12890	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
L3V45_RS12915	COG0860	N-Acetylmuramoyl-L-alanine amidase
L3V45_RS12915	COG3103	Sh3 type 3 domain protein
L3V45_RS12915	COG4991	sh3 domain protein
L3V45_RS12925	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L3V45_RS12935	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
L3V45_RS12935	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
L3V45_RS12940	COG5416	Lipopolysaccharide assembly protein A domain
L3V45_RS12945	COG0490	domain, Protein
L3V45_RS12950	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
L3V45_RS12950	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
L3V45_RS12960	COG2244	polysaccharide biosynthetic process
L3V45_RS12965	COG2323	membrane
L3V45_RS12975	COG1862	Preprotein translocase
L3V45_RS13015	COG1388	LysM domain
L3V45_RS13025	COG0157	Belongs to the NadC ModD family
L3V45_RS13030	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
L3V45_RS13035	COG1104	cysteine desulfurase activity
L3V45_RS13040	COG1827	regulation of RNA biosynthetic process
L3V45_RS13045	COG0077	Prephenate dehydratase
L3V45_RS13060	COG3290	protein histidine kinase activity
L3V45_RS13065	COG0211	Belongs to the bacterial ribosomal protein bL27 family
L3V45_RS13070	COG2868	ribosomal protein
L3V45_RS13080	COG1994	Peptidase M50
L3V45_RS13085	COG0739	heme binding
L3V45_RS13090	COG2894	cell division
L3V45_RS13100	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
L3V45_RS13110	COG1077	Cell shape determining protein MreB Mrl
L3V45_RS13130	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
L3V45_RS13135	COG0285	dihydrofolate synthase activity
L3V45_RS13140	COG0525	valine-tRNA ligase activity
L3V45_RS13150	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
L3V45_RS13155	COG1388	LysM domain
L3V45_RS13165	COG0113	porphobilinogen synthase activity
L3V45_RS13170	COG1587	Uroporphyrinogen-III synthase
L3V45_RS13180	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
L3V45_RS13200	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
L3V45_RS13205	COG1067	ATP-dependent peptidase activity
L3V45_RS13205	COG0470	DNA polymerase III
L3V45_RS13220	COG1477	protein flavinylation
L3V45_RS13220	COG0457	Tetratricopeptide repeat
L3V45_RS13235	COG0473	3-isopropylmalate dehydrogenase activity
L3V45_RS13250	COG0440	acetolactate synthase activity
L3V45_RS13255	COG0028	Belongs to the TPP enzyme family
L3V45_RS13280	COG0622	Phosphoesterase
L3V45_RS13285	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
L3V45_RS13295	COG5401	PFAM Sporulation and spore germination
L3V45_RS13305	COG1846	Transcriptional regulator
L3V45_RS13310	COG2197	response regulator
L3V45_RS13315	COG0824	Thioesterase
L3V45_RS13320	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
L3V45_RS13325	COG1053	succinate dehydrogenase
L3V45_RS13330	COG2009	succinate dehydrogenase
L3V45_RS13335	COG1719	4-vinyl reductase, 4VR
L3V45_RS13340	COG0527	aspartate kinase activity
L3V45_RS13350	COG3118	belongs to the thioredoxin family
L3V45_RS13355	COG3534	alpha-L-arabinofuranosidase
L3V45_RS13360	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
L3V45_RS13365	COG2086	electron transfer activity
L3V45_RS13370	COG1024	Enoyl-CoA hydratase
L3V45_RS13375	COG1309	transcriptional regulator
L3V45_RS13380	COG0318	PFAM AMP-dependent synthetase and ligase
L3V45_RS13390	COG3766	membrane
L3V45_RS13400	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
L3V45_RS13400	COG1796	DNA polymerase
L3V45_RS13405	COG1286	toxin biosynthetic process
L3V45_RS13420	COG0072	phenylalanine-tRNA ligase activity
L3V45_RS13420	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L3V45_RS13425	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
L3V45_RS13430	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L3V45_RS13440	COG3835	regulator
L3V45_RS13445	COG0277	FAD linked oxidase domain protein
L3V45_RS13450	COG0247	lactate metabolic process
L3V45_RS13455	COG1966	Carbon starvation protein
L3V45_RS13460	COG3534	alpha-L-arabinofuranosidase
L3V45_RS13465	COG0395	ABC-type sugar transport system, permease component
L3V45_RS13470	COG1175	transmembrane transport
L3V45_RS13475	COG1653	transport
L3V45_RS13485	COG0647	UMP catabolic process
L3V45_RS13490	COG0235	Class ii aldolase
L3V45_RS13495	COG1069	ribulokinase activity
L3V45_RS13500	COG2160	L-arabinose isomerase activity
L3V45_RS13505	COG3507	Belongs to the glycosyl hydrolase 43 family
L3V45_RS13510	COG1363	Peptidase, m42
L3V45_RS13520	COG3326	Membrane
L3V45_RS13525	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
L3V45_RS13535	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
L3V45_RS13540	COG1346	cytolysis
L3V45_RS13545	COG1380	Effector of murein hydrolase LrgA
L3V45_RS13550	COG3279	Response regulator of the LytR AlgR family
L3V45_RS13555	COG3275	phosphorelay sensor kinase activity
L3V45_RS13560	COG1011	Hydrolase
L3V45_RS13575	COG0398	Pfam SNARE associated Golgi protein
L3V45_RS13580	COG1484	DNA-dependent DNA replication
L3V45_RS13585	COG3611	Membrane attachment protein
L3V45_RS13600	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
L3V45_RS13605	COG1733	regulation of RNA biosynthetic process
L3V45_RS13610	COG2814	Major facilitator Superfamily
L3V45_RS13615	COG0656	L-ascorbic acid biosynthetic process
L3V45_RS13620	COG0237	dephospho-CoA kinase activity
L3V45_RS13625	COG1971	Probably functions as a manganese efflux pump
L3V45_RS13630	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
L3V45_RS13635	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
L3V45_RS13635	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
L3V45_RS13640	COG5002	protein histidine kinase activity
L3V45_RS13645	COG0745	RESPONSE REGULATOR receiver
L3V45_RS13655	COG0538	isocitrate dehydrogenase activity
L3V45_RS13660	COG0372	Belongs to the citrate synthase family
L3V45_RS13680	COG0628	permease
L3V45_RS13685	COG3030	protein affecting phage T7 exclusion by the F plasmid
L3V45_RS13690	COG0469	pyruvate kinase activity
L3V45_RS13710	COG0281	malic enzyme
L3V45_RS13715	COG0587	DNA-directed DNA polymerase activity
L3V45_RS13735	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
L3V45_RS13745	COG4109	DRTGG domain
L3V45_RS13755	COG1028	Short-chain dehydrogenase reductase Sdr
L3V45_RS13770	COG0521	Mo-molybdopterin cofactor biosynthetic process
L3V45_RS13780	COG0827	DNA restriction-modification system
L3V45_RS13785	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
L3V45_RS13790	COG3874	Sporulation protein YtfJ
L3V45_RS13800	COG1714	RDD family
L3V45_RS13805	COG0616	signal peptide processing
L3V45_RS13810	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
L3V45_RS13815	COG1574	metal-dependent hydrolase with the TIM-barrel fold
L3V45_RS13820	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L3V45_RS13835	COG1104	cysteine desulfurase activity
L3V45_RS13840	COG1114	Component of the transport system for branched-chain amino acids
L3V45_RS13850	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
L3V45_RS13855	COG1309	transcriptional regulator
L3V45_RS13860	COG1956	GAF domain-containing protein
L3V45_RS13865	COG2203	Gaf domain
L3V45_RS13865	COG2199	diguanylate cyclase activity
L3V45_RS13875	COG1012	belongs to the aldehyde dehydrogenase family
L3V45_RS13880	COG4282	regulation of fungal-type cell wall biogenesis
L3V45_RS13885	COG1017	nitric oxide dioxygenase activity
L3V45_RS13885	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L3V45_RS13895	COG0693	protein deglycase activity
L3V45_RS13910	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
L3V45_RS13915	COG1378	Sugar-specific transcriptional regulator TrmB
L3V45_RS13935	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L3V45_RS13940	COG0454	-acetyltransferase
L3V45_RS13945	COG0517	IMP dehydrogenase activity
L3V45_RS13950	COG0123	including yeast histone deacetylase and acetoin utilization protein
L3V45_RS13955	COG1360	Flagellar Motor Protein
L3V45_RS13960	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
L3V45_RS13965	COG1609	Transcriptional regulator
L3V45_RS13970	COG1605	Chorismate mutase
L3V45_RS13970	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
L3V45_RS13975	COG3118	belongs to the thioredoxin family
L3V45_RS13980	COG4980	gas vesicle protein
L3V45_RS13985	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
L3V45_RS13995	COG1674	ftsk spoiiie
L3V45_RS14000	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L3V45_RS14010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L3V45_RS14020	COG1363	Peptidase, m42
L3V45_RS14025	COG5584	Small secreted protein
L3V45_RS14030	COG0281	malic enzyme
L3V45_RS14035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L3V45_RS14050	COG0510	thiamine kinase activity
L3V45_RS14055	COG1597	lipid kinase activity
L3V45_RS14065	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
L3V45_RS14070	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L3V45_RS14075	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
L3V45_RS14080	COG2252	PERMEase
L3V45_RS14085	COG4473	ABC transporter
L3V45_RS14090	COG1131	(ABC) transporter
L3V45_RS14095	COG1349	DNA-binding transcription factor activity
L3V45_RS14100	COG1187	pseudouridine synthase activity
L3V45_RS14105	COG2244	polysaccharide biosynthetic process
L3V45_RS14110	COG2081	HI0933 family
L3V45_RS14115	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L3V45_RS14125	COG1609	Transcriptional regulator
L3V45_RS14130	COG1653	transport
L3V45_RS14135	COG1175	transmembrane transport
L3V45_RS14140	COG0395	ABC-type sugar transport system, permease component
L3V45_RS14145	COG1486	melibiose metabolic process
L3V45_RS14155	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
L3V45_RS14170	COG1366	Belongs to the anti-sigma-factor antagonist family
L3V45_RS14170	COG2202	Pas domain
L3V45_RS14175	COG2814	Major facilitator Superfamily
L3V45_RS14180	COG5522	Integral membrane protein (intg_mem_TP0381)
L3V45_RS14185	COG0577	efflux transmembrane transporter activity
L3V45_RS14190	COG1136	(ABC) transporter
L3V45_RS14195	COG2205	protein histidine kinase activity
L3V45_RS14200	COG0745	RESPONSE REGULATOR receiver
L3V45_RS14205	COG0577	efflux transmembrane transporter activity
L3V45_RS14210	COG1136	(ABC) transporter
L3V45_RS14230	COG1131	(ABC) transporter
L3V45_RS14235	COG1725	Transcriptional regulator
L3V45_RS14250	COG1242	4 iron, 4 sulfur cluster binding
L3V45_RS14255	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
L3V45_RS14265	COG0584	glycerophosphoryl diester phosphodiesterase
L3V45_RS14275	COG2267	carboxylic ester hydrolase activity
L3V45_RS14280	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
L3V45_RS14285	COG1113	amino acid transport
L3V45_RS14290	COG0367	asparagine synthase
L3V45_RS14310	COG1506	peptidase
L3V45_RS14315	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L3V45_RS14320	COG1116	anion transmembrane transporter activity
L3V45_RS14325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L3V45_RS14330	COG0494	nUDIX hydrolase
L3V45_RS14335	COG4824	toxin secretion phage lysis holin
L3V45_RS14340	COG0783	Belongs to the Dps family
L3V45_RS14365	COG0288	reversible hydration of carbon dioxide
L3V45_RS14375	COG1271	oxidase subunit
L3V45_RS14380	COG1294	oxidase, subunit
L3V45_RS14390	COG4948	Mandelate Racemase Muconate Lactonizing
L3V45_RS14400	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
L3V45_RS14405	COG0596	Alpha beta hydrolase
L3V45_RS14415	COG1169	isochorismate synthase
L3V45_RS14420	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
L3V45_RS14425	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
L3V45_RS14550	COG3859	Proton-coupled thiamine transporter YuaJ
L3V45_RS14555	COG2268	Band 7 protein
L3V45_RS14560	COG1585	Membrane protein implicated in regulation of membrane protease activity
L3V45_RS14565	COG2318	DinB family
L3V45_RS14575	COG1454	alcohol dehydrogenase
L3V45_RS14580	COG1012	belongs to the aldehyde dehydrogenase family
L3V45_RS14585	COG1510	regulation of RNA biosynthetic process
L3V45_RS14595	COG0569	domain protein
L3V45_RS14600	COG1705	Flagellar rod assembly protein muramidase FlgJ
L3V45_RS14605	COG1017	nitric oxide dioxygenase activity
L3V45_RS14605	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L3V45_RS14630	COG0628	permease
L3V45_RS14635	COG0673	inositol 2-dehydrogenase activity
L3V45_RS14640	COG0693	protein deglycase activity
L3V45_RS14645	COG0840	transmembrane signaling receptor activity
L3V45_RS14650	COG0840	transmembrane signaling receptor activity
L3V45_RS14655	COG0840	transmembrane signaling receptor activity
L3V45_RS14660	COG0840	transmembrane signaling receptor activity
L3V45_RS14675	COG2070	2-Nitropropane dioxygenase
L3V45_RS14680	COG0432	Pfam Uncharacterised protein family UPF0047
L3V45_RS14685	COG0366	Alpha amylase catalytic
L3V45_RS14690	COG1253	flavin adenine dinucleotide binding
L3V45_RS14695	COG2738	Putative neutral zinc metallopeptidase
L3V45_RS14710	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L3V45_RS14740	COG1335	isochorismatase
L3V45_RS14745	COG1979	alcohol dehydrogenase
L3V45_RS14750	COG1979	alcohol dehydrogenase
L3V45_RS14755	COG2155	Conserved Protein
L3V45_RS14760	COG1098	S1 RNA binding domain
L3V45_RS14765	COG0436	Aminotransferase
L3V45_RS14770	COG1522	sequence-specific DNA binding
L3V45_RS14775	COG2267	carboxylic ester hydrolase activity
L3V45_RS14785	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
L3V45_RS14790	COG2205	protein histidine kinase activity
L3V45_RS14800	COG5018	Exonuclease
L3V45_RS14805	COG2814	Major facilitator Superfamily
L3V45_RS14810	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L3V45_RS14815	COG3011	Protein conserved in bacteria
L3V45_RS14825	COG3290	protein histidine kinase activity
L3V45_RS14830	COG4565	transcriptional regulatory protein
L3V45_RS14835	COG1744	ABC transporter substrate-binding protein PnrA-like
L3V45_RS14840	COG3845	ABC transporter
L3V45_RS14845	COG4603	Belongs to the binding-protein-dependent transport system permease family
L3V45_RS14850	COG1079	Belongs to the binding-protein-dependent transport system permease family
L3V45_RS14860	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L3V45_RS14860	COG2111	Na H antiporter
L3V45_RS14865	COG2111	Na H antiporter
L3V45_RS14870	COG1006	Multisubunit Na H antiporter MnhC subunit
L3V45_RS14875	COG0651	ATP synthesis coupled electron transport
L3V45_RS14880	COG1863	multisubunit Na H antiporter MnhE subunit
L3V45_RS14885	COG2212	antiporter activity
L3V45_RS14890	COG1320	monovalent cation:proton antiporter activity
L3V45_RS14895	COG2050	protein possibly involved in aromatic compounds catabolism
L3V45_RS14900	COG2197	response regulator
L3V45_RS14905	COG4585	Histidine kinase
L3V45_RS14930	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
L3V45_RS14935	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
L3V45_RS14940	COG1335	isochorismatase
L3V45_RS14945	COG5506	Protein of unknown function (DUF1694)
L3V45_RS14960	COG0628	permease
L3V45_RS14970	COG1418	mRNA catabolic process
L3V45_RS14975	COG1028	Short-chain dehydrogenase reductase Sdr
L3V45_RS14985	COG1511	domain protein
L3V45_RS14990	COG1674	ftsk spoiiie
L3V45_RS14990	COG0433	COG0433 Predicted ATPase
L3V45_RS14995	COG4499	WXG100 protein secretion system (Wss), protein YukC
L3V45_RS15000	COG5417	Belongs to the EsaB family
L3V45_RS15005	COG4842	Belongs to the WXG100 family
L3V45_RS15010	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
L3V45_RS15010	COG2508	Transcriptional regulator
L3V45_RS15015	COG0686	Belongs to the AlaDH PNT family
L3V45_RS15020	COG5634	Uncharacterized conserved protein (DUF2278)
L3V45_RS15025	COG3251	PFAM MbtH domain protein
L3V45_RS15030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L3V45_RS15035	COG3433	isochorismatase activity
L3V45_RS15035	COG1535	isochorismatase
L3V45_RS15040	COG1021	2,3-dihydroxybenzoate-AMP ligase
L3V45_RS15045	COG1169	isochorismate synthase
L3V45_RS15050	COG1028	Short-chain dehydrogenase reductase Sdr
L3V45_RS15055	COG2819	hydrolase of the alpha beta superfamily
L3V45_RS15060	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
L3V45_RS15065	COG1268	BioY protein
L3V45_RS15070	COG2056	Na+-H+ antiporter family
L3V45_RS15080	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
L3V45_RS15085	COG3584	3D domain protein
L3V45_RS15100	COG1252	NADH dehydrogenase
L3V45_RS15130	COG1131	(ABC) transporter
L3V45_RS15155	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
L3V45_RS15160	COG0316	Belongs to the HesB IscA family
L3V45_RS15170	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L3V45_RS15180	COG1252	NADH dehydrogenase
L3V45_RS15185	COG4837	Protein of unknown function (DUF1462)
L3V45_RS15190	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
L3V45_RS15195	COG0823	Involved in the tonB-independent uptake of proteins
L3V45_RS15195	COG4946	Tricorn protease homolog
L3V45_RS15195	COG1506	peptidase
L3V45_RS15205	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
L3V45_RS15210	COG0460	homoserine dehydrogenase
L3V45_RS15215	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
L3V45_RS15220	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
L3V45_RS15225	COG0647	UMP catabolic process
L3V45_RS15230	COG2445	Protein of unknown function DUF86
L3V45_RS15235	COG4470	Protein conserved in bacteria
L3V45_RS15245	COG0739	heme binding
L3V45_RS15255	COG0737	Belongs to the 5'-nucleotidase family
L3V45_RS15260	COG0730	response to heat
L3V45_RS15265	COG1801	Protein of unknown function DUF72
L3V45_RS15280	COG2508	Transcriptional regulator
L3V45_RS15305	COG2814	Major facilitator Superfamily
L3V45_RS15310	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
L3V45_RS15315	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
L3V45_RS15320	COG2356	endonuclease I
L3V45_RS15325	COG3842	ATPase activity
L3V45_RS15330	COG2188	Transcriptional regulator
L3V45_RS15335	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L3V45_RS15340	COG0395	ABC-type sugar transport system, permease component
L3V45_RS15345	COG1175	transmembrane transport
L3V45_RS15350	COG1653	transport
L3V45_RS15355	COG2222	sugar isomerase
L3V45_RS15360	COG0789	Transcriptional regulator
L3V45_RS15370	COG0322	excinuclease ABC activity
L3V45_RS15375	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L3V45_RS15380	COG2226	methyltransferase
L3V45_RS15390	COG3409	Peptidoglycan-binding domain 1 protein
L3V45_RS15395	COG0719	Fe-S assembly protein
L3V45_RS15400	COG0822	iron-sulfur transferase activity
L3V45_RS15405	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
L3V45_RS15410	COG0719	Fe-S assembly protein
L3V45_RS15415	COG0396	ATPase activity
L3V45_RS15425	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L3V45_RS15430	COG1464	Belongs to the NlpA lipoprotein family
L3V45_RS15435	COG2011	ABC-type metal ion transport system permease component
L3V45_RS15440	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L3V45_RS15450	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L3V45_RS15455	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
L3V45_RS15470	COG1393	Belongs to the ArsC family
L3V45_RS15475	COG1960	acyl-CoA dehydrogenase activity
L3V45_RS15480	COG0183	Belongs to the thiolase family
L3V45_RS15485	COG1250	3-hydroxyacyl-CoA dehydrogenase
L3V45_RS15485	COG1024	Enoyl-CoA hydratase
L3V45_RS15505	COG5577	PFAM Coat F domain
L3V45_RS15510	COG1846	Transcriptional regulator
L3V45_RS15515	COG0477	Major facilitator Superfamily
L3V45_RS15520	COG0583	DNA-binding transcription factor activity
L3V45_RS15540	COG1120	ATPase activity
L3V45_RS15555	COG1028	Short-chain dehydrogenase reductase Sdr
L3V45_RS15560	COG0783	Belongs to the Dps family
L3V45_RS15565	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L3V45_RS15570	COG0745	RESPONSE REGULATOR receiver
L3V45_RS15575	COG2770	Histidine kinase
L3V45_RS15575	COG2205	protein histidine kinase activity
L3V45_RS15585	COG1309	transcriptional regulator
L3V45_RS15590	COG0114	fumarate hydratase activity
L3V45_RS15600	COG0697	spore germination
L3V45_RS15605	COG0814	amino acid
L3V45_RS15615	COG2197	response regulator
L3V45_RS15620	COG4585	Histidine kinase
L3V45_RS15625	COG4758	membrane
L3V45_RS15630	COG3595	metallopeptidase activity
L3V45_RS15635	COG1842	Phage shock protein A
L3V45_RS15640	COG4758	membrane
L3V45_RS15645	COG2814	Major facilitator Superfamily
L3V45_RS15650	COG2096	Adenosyltransferase
L3V45_RS15655	COG1120	ATPase activity
L3V45_RS15660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L3V45_RS15665	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
L3V45_RS15670	COG1028	Short-chain dehydrogenase reductase Sdr
L3V45_RS15675	COG3386	PFAM SMP-30 Gluconolaconase
L3V45_RS15680	COG2205	protein histidine kinase activity
L3V45_RS15685	COG0745	RESPONSE REGULATOR receiver
L3V45_RS15695	COG1191	sigma factor activity
L3V45_RS15705	COG2140	Oxalate decarboxylase
L3V45_RS15715	COG1120	ATPase activity
L3V45_RS15720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L3V45_RS15725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L3V45_RS15730	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
L3V45_RS15735	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
L3V45_RS15740	COG0531	amino acid
L3V45_RS15750	COG1988	membrane-bound metal-dependent
L3V45_RS15755	COG1368	sulfuric ester hydrolase activity
L3V45_RS15760	COG1910	domain protein
L3V45_RS15765	COG0725	ABC transporter, periplasmic molybdate-binding protein
L3V45_RS15770	COG4149	molybdate abc transporter
L3V45_RS15775	COG2197	response regulator
L3V45_RS15780	COG3850	Histidine kinase
L3V45_RS15785	COG1131	(ABC) transporter
L3V45_RS15795	COG0842	Transport permease protein
L3V45_RS15800	COG0656	L-ascorbic acid biosynthetic process
L3V45_RS15820	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
L3V45_RS15825	COG3973	AAA domain
L3V45_RS15830	COG2860	membrane
L3V45_RS15840	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
L3V45_RS15845	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L3V45_RS15850	COG2217	Heavy metal translocating P-type atpase
L3V45_RS15855	COG2217	Heavy metal translocating P-type atpase
L3V45_RS15860	COG2608	mercury ion transmembrane transporter activity
L3V45_RS15865	COG1937	Protein conserved in bacteria
L3V45_RS15870	COG0673	inositol 2-dehydrogenase activity
L3V45_RS15885	COG2814	Major facilitator Superfamily
L3V45_RS15900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L3V45_RS15905	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
L3V45_RS15910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L3V45_RS15915	COG1126	abc transporter atp-binding protein
L3V45_RS15920	COG0765	amino acid transport
L3V45_RS15925	COG0765	amino acid transport
L3V45_RS15930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L3V45_RS15935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L3V45_RS15940	COG0454	-acetyltransferase
L3V45_RS15945	COG0583	DNA-binding transcription factor activity
L3V45_RS15950	COG1028	Short-chain dehydrogenase reductase Sdr
L3V45_RS15955	COG2732	(Barnase) inhibitor
L3V45_RS15970	COG0557	exoribonuclease II activity
L3V45_RS15975	COG1647	Serine aminopeptidase, S33
L3V45_RS15980	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
L3V45_RS15985	COG1476	TRANSCRIPTIONal
L3V45_RS15990	COG1396	sequence-specific DNA binding
L3V45_RS15995	COG1396	sequence-specific DNA binding
L3V45_RS16000	COG1733	regulation of RNA biosynthetic process
L3V45_RS16025	COG1131	(ABC) transporter
L3V45_RS16030	COG1174	glycine betaine transport
L3V45_RS16035	COG1732	Glycine betaine
L3V45_RS16040	COG1174	glycine betaine transport
L3V45_RS16045	COG1125	glycine betaine transport
L3V45_RS16045	COG0517	IMP dehydrogenase activity
L3V45_RS16050	COG1510	regulation of RNA biosynthetic process
L3V45_RS16055	COG1174	glycine betaine transport
L3V45_RS16060	COG1732	Glycine betaine
L3V45_RS16065	COG1174	glycine betaine transport
L3V45_RS16070	COG0517	IMP dehydrogenase activity
L3V45_RS16070	COG1125	glycine betaine transport
L3V45_RS16075	COG1510	regulation of RNA biosynthetic process
L3V45_RS16080	COG2095	MarC family integral membrane protein
L3V45_RS16085	COG3064	Membrane
L3V45_RS16090	COG4640	response to antibiotic
L3V45_RS16095	COG0456	acetyltransferase
L3V45_RS16110	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
L3V45_RS16125	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
L3V45_RS16130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L3V45_RS16135	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
L3V45_RS16145	COG2234	aminopeptidase activity
L3V45_RS16165	COG0126	phosphoglycerate kinase activity
L3V45_RS16170	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
L3V45_RS16175	COG2390	Transcriptional regulator
L3V45_RS16180	COG2814	Major facilitator Superfamily
L3V45_RS16185	COG1609	Transcriptional regulator
L3V45_RS16190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L3V45_RS16200	COG0583	DNA-binding transcription factor activity
L3V45_RS16205	COG0697	spore germination
L3V45_RS16210	COG1113	amino acid transport
L3V45_RS16215	COG1737	Transcriptional regulator
L3V45_RS16220	COG1070	Carbohydrate kinase
L3V45_RS16245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L3V45_RS16250	COG2186	Transcriptional regulator
L3V45_RS16255	COG1620	l-lactate permease
L3V45_RS16260	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
L3V45_RS16270	COG5039	Polysaccharide pyruvyl transferase
L3V45_RS16275	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
L3V45_RS16280	COG0110	maltose O-acetyltransferase activity
L3V45_RS16285	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
L3V45_RS16290	COG2244	polysaccharide biosynthetic process
L3V45_RS16295	COG1216	Glycosyl transferase, family 2
L3V45_RS16300	COG5039	Polysaccharide pyruvyl transferase
L3V45_RS16305	COG1216	Glycosyl transferase, family 2
L3V45_RS16315	COG0438	transferase activity, transferring glycosyl groups
L3V45_RS16320	COG1215	transferase activity, transferring glycosyl groups
L3V45_RS16325	COG0438	transferase activity, transferring glycosyl groups
L3V45_RS16330	COG1086	Polysaccharide biosynthesis protein
L3V45_RS16335	COG0489	protein tyrosine kinase activity
L3V45_RS16340	COG3944	biosynthesis protein
L3V45_RS16345	COG1396	sequence-specific DNA binding
L3V45_RS16350	COG2272	Belongs to the type-B carboxylesterase lipase family
L3V45_RS16360	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
L3V45_RS16365	COG2364	Membrane
L3V45_RS16370	COG0456	acetyltransferase
L3V45_RS16375	COG3479	Phenolic acid decarboxylase
L3V45_RS16435	COG2223	nitrite transmembrane transporter activity
L3V45_RS16440	COG1609	Transcriptional regulator
L3V45_RS16450	COG0583	DNA-binding transcription factor activity
L3V45_RS16455	COG2828	Protein conserved in bacteria
L3V45_RS16460	COG2814	Major facilitator Superfamily
L3V45_RS16460	COG0477	Major facilitator Superfamily
L3V45_RS16465	COG1611	Belongs to the LOG family
L3V45_RS16470	COG1694	Mazg nucleotide pyrophosphohydrolase
L3V45_RS16475	COG0659	secondary active sulfate transmembrane transporter activity
L3V45_RS16480	COG0288	reversible hydration of carbon dioxide
L3V45_RS16485	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
L3V45_RS16490	COG4290	ribonuclease
L3V45_RS16495	COG2162	N-hydroxyarylamine O-acetyltransferase activity
L3V45_RS16500	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
L3V45_RS16510	COG0391	Required for morphogenesis under gluconeogenic growth conditions
L3V45_RS16520	COG1051	belongs to the nudix hydrolase family
L3V45_RS16525	COG0492	ferredoxin-NADP+ reductase activity
L3V45_RS16530	COG3883	PFAM NLP P60 protein
L3V45_RS16530	COG0791	NLP P60 protein
L3V45_RS16535	COG0457	Tetratricopeptide repeat
L3V45_RS16540	COG5002	protein histidine kinase activity
L3V45_RS16545	COG0745	RESPONSE REGULATOR receiver
L3V45_RS16555	COG1132	(ABC) transporter
L3V45_RS16560	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
L3V45_RS16560	COG0140	phosphoribosyl-ATP diphosphatase activity
L3V45_RS16585	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
L3V45_RS16600	COG4990	cell redox homeostasis
L3V45_RS16605	COG0110	maltose O-acetyltransferase activity
L3V45_RS16625	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
L3V45_RS16635	COG2188	Transcriptional regulator
L3V45_RS16640	COG1309	transcriptional regulator
L3V45_RS16645	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L3V45_RS16650	COG1950	PFAM Membrane protein of
L3V45_RS16655	COG1983	PspC domain protein
L3V45_RS16660	COG3595	metallopeptidase activity
L3V45_RS16675	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
L3V45_RS16685	COG4897	Protein conserved in bacteria
L3V45_RS16690	COG0574	Belongs to the PEP-utilizing enzyme family
L3V45_RS16690	COG3848	Pyruvate phosphate dikinase
L3V45_RS16695	COG1309	transcriptional regulator
L3V45_RS16700	COG2814	Major facilitator Superfamily
L3V45_RS16710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L3V45_RS16720	COG0793	Belongs to the peptidase S41A family
L3V45_RS16720	COG3409	Peptidoglycan-binding domain 1 protein
L3V45_RS16725	COG3420	alginic acid biosynthetic process
L3V45_RS16730	COG2177	Part of the ABC transporter FtsEX involved in
L3V45_RS16735	COG2884	Cell division ATP-binding protein ftsE
L3V45_RS16740	COG2010	Cytochrome c
L3V45_RS16745	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L3V45_RS16760	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
L3V45_RS16775	COG1516	flagellar protein fliS
L3V45_RS16780	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
L3V45_RS16785	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
L3V45_RS16805	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
L3V45_RS16810	COG4786	Flagellar basal body rod
L3V45_RS16810	COG1256	bacterial-type flagellum assembly
L3V45_RS16815	COG3418	PFAM FlgN family protein
L3V45_RS16820	COG2747	anti-sigma28 factor FlgM
L3V45_RS16830	COG1040	competence protein
L3V45_RS16840	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
L3V45_RS16845	COG1307	EDD domain protein, DegV family
L3V45_RS16850	COG2197	response regulator
L3V45_RS16855	COG4585	Histidine kinase
L3V45_RS16860	COG1739	Uncharacterized protein family UPF0029
L3V45_RS16865	COG1316	TRANSCRIPTIONal
L3V45_RS16870	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
L3V45_RS16875	COG0438	transferase activity, transferring glycosyl groups
L3V45_RS16880	COG1215	transferase activity, transferring glycosyl groups
L3V45_RS16885	COG3206	protein involved in exopolysaccharide biosynthesis
L3V45_RS16890	COG3307	-O-antigen
L3V45_RS16895	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
L3V45_RS16900	COG0438	transferase activity, transferring glycosyl groups
L3V45_RS16900	COG0297	glycogen (starch) synthase activity
L3V45_RS16905	COG2244	polysaccharide biosynthetic process
L3V45_RS16915	COG2247	cell wall binding repeat
L3V45_RS16915	COG0860	N-Acetylmuramoyl-L-alanine amidase
L3V45_RS16920	COG2385	sporulation resulting in formation of a cellular spore
L3V45_RS16920	COG2247	cell wall binding repeat
L3V45_RS16930	COG1316	TRANSCRIPTIONal
L3V45_RS16935	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
L3V45_RS16940	COG1210	Utp--glucose-1-phosphate uridylyltransferase
L3V45_RS16945	COG1134	teichoic acid transport
L3V45_RS16950	COG1682	transport, permease protein
L3V45_RS16955	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
L3V45_RS16965	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
L3V45_RS16970	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
L3V45_RS16975	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
L3V45_RS16980	COG4193	domain, Protein
L3V45_RS16985	COG1482	cell wall glycoprotein biosynthetic process
L3V45_RS16990	COG0697	spore germination
L3V45_RS16995	COG0814	amino acid
L3V45_RS17005	COG1215	transferase activity, transferring glycosyl groups
L3V45_RS17010	COG2814	Major facilitator Superfamily
L3V45_RS17015	COG1316	TRANSCRIPTIONal
L3V45_RS17020	COG0561	phosphatase activity
L3V45_RS17025	COG2433	Pfam Transposase IS66
L3V45_RS17030	COG0791	NLP P60 protein
L3V45_RS17040	COG2843	Capsule synthesis protein
L3V45_RS17050	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
L3V45_RS17055	COG0697	spore germination
L3V45_RS17060	COG0814	amino acid
L3V45_RS17070	COG1609	Transcriptional regulator
L3V45_RS17075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L3V45_RS17085	COG1129	ABC transporter
L3V45_RS17090	COG1172	Belongs to the binding-protein-dependent transport system permease family
L3V45_RS17095	COG1879	ABC-type sugar transport system periplasmic component
L3V45_RS17100	COG3103	Sh3 type 3 domain protein
L3V45_RS17105	COG2249	NAD(P)H dehydrogenase (quinone) activity
L3V45_RS17110	COG3527	Alpha-acetolactate decarboxylase
L3V45_RS17115	COG0028	Belongs to the TPP enzyme family
L3V45_RS17120	COG0583	DNA-binding transcription factor activity
L3V45_RS17125	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
L3V45_RS17140	COG5337	Spore coat protein CotH
L3V45_RS17150	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L3V45_RS17160	COG0405	Gamma-glutamyltransferase
L3V45_RS17165	COG1522	sequence-specific DNA binding
L3V45_RS17170	COG2059	Chromate
L3V45_RS17175	COG2059	Chromate
L3V45_RS17185	COG0655	NAD(P)H dehydrogenase (quinone) activity
L3V45_RS17190	COG0583	DNA-binding transcription factor activity
L3V45_RS17235	COG5444	nuclease activity
L3V45_RS17250	COG3878	Protein conserved in bacteria
L3V45_RS17255	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
L3V45_RS17260	COG4464	protein tyrosine phosphatase activity
L3V45_RS17265	COG0489	protein tyrosine kinase activity
L3V45_RS17270	COG3944	biosynthesis protein
L3V45_RS17280	COG4715	Zinc finger, swim domain protein
L3V45_RS17285	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
L3V45_RS17290	COG0561	phosphatase activity
L3V45_RS17295	COG1349	DNA-binding transcription factor activity
L3V45_RS17300	COG0629	single-stranded DNA binding
L3V45_RS17325	COG0457	Tetratricopeptide repeat
L3V45_RS17330	COG4786	Flagellar basal body rod
L3V45_RS17335	COG4786	Flagellar basal body rod
L3V45_RS17340	COG1077	Cell shape determining protein MreB Mrl
L3V45_RS17345	COG1609	Transcriptional regulator
L3V45_RS17350	COG1846	Transcriptional regulator
L3V45_RS17355	COG2814	Major facilitator Superfamily
L3V45_RS17360	COG1953	Uracil, thiamine, allantoin
L3V45_RS17365	COG0477	Major facilitator Superfamily
L3V45_RS17370	COG1335	isochorismatase
L3V45_RS17375	COG0004	ammonium transporteR
L3V45_RS17380	COG0347	Belongs to the P(II) protein family
L3V45_RS17385	COG0772	Belongs to the SEDS family
L3V45_RS17390	COG0671	phosphoesterase, PA-phosphatase related
L3V45_RS17400	COG0739	heme binding
L3V45_RS17405	COG1247	-acetyltransferase
L3V45_RS17420	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L3V45_RS17430	COG0726	polysaccharide deacetylase
L3V45_RS17440	COG1959	2 iron, 2 sulfur cluster binding
L3V45_RS17455	COG0831	urea catabolic process
L3V45_RS17460	COG3237	CsbD-like
L3V45_RS17465	COG1994	Peptidase M50
L3V45_RS17470	COG0457	Tetratricopeptide repeat
L3V45_RS17480	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
L3V45_RS17490	COG2304	oxidoreductase activity
L3V45_RS17495	COG2304	oxidoreductase activity
L3V45_RS17500	COG2385	sporulation resulting in formation of a cellular spore
L3V45_RS17505	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
L3V45_RS17515	COG4836	Membrane
L3V45_RS17585	COG0698	ribose 5-phosphate isomerase
L3V45_RS17590	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
L3V45_RS17600	COG0009	L-threonylcarbamoyladenylate synthase
L3V45_RS17605	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
L3V45_RS17625	COG2890	protein-(glutamine-N5) methyltransferase activity
L3V45_RS17630	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
L3V45_RS17635	COG0346	lactoylglutathione lyase activity
L3V45_RS17640	COG0789	Transcriptional regulator
L3V45_RS17645	COG0679	Auxin Efflux Carrier
L3V45_RS17650	COG0281	malic enzyme
L3V45_RS17665	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
L3V45_RS17675	COG1494	fructose-1,6-bisphosphatase
L3V45_RS17680	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
L3V45_RS17690	COG0191	fructose-bisphosphate aldolase activity
L3V45_RS17695	COG2204	response regulator
L3V45_RS17700	COG4821	SIS domain
L3V45_RS17715	COG2181	nitrate reductase activity
L3V45_RS17715	COG0247	lactate metabolic process
L3V45_RS17720	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L3V45_RS17735	COG1132	(ABC) transporter
L3V45_RS17740	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L3V45_RS17750	COG2181	nitrate reductase activity
L3V45_RS17755	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
L3V45_RS17760	COG1140	nitrate reductase beta subunit
L3V45_RS17765	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
L3V45_RS17770	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L3V45_RS17780	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L3V45_RS17785	COG2223	nitrite transmembrane transporter activity
L3V45_RS17795	COG4506	Protein conserved in bacteria
L3V45_RS17800	COG0457	Tetratricopeptide repeat
L3V45_RS17810	COG0010	Belongs to the arginase family
L3V45_RS17815	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
L3V45_RS17820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L3V45_RS17835	COG1994	Peptidase M50
L3V45_RS17840	COG1942	4-Oxalocrotonate Tautomerase
L3V45_RS17845	COG1846	Transcriptional regulator
L3V45_RS17850	COG0531	amino acid
L3V45_RS17855	COG3465	dGTPase activity
L3V45_RS17860	COG1078	dGTPase activity
L3V45_RS17875	COG1695	Transcriptional regulator
L3V45_RS17895	COG0583	DNA-binding transcription factor activity
L3V45_RS17900	COG2855	membrane
L3V45_RS17905	COG0280	phosphate acetyltransferase
L3V45_RS17915	COG1028	Short-chain dehydrogenase reductase Sdr
L3V45_RS17920	COG0436	Aminotransferase
L3V45_RS17950	COG2814	Major facilitator Superfamily
L3V45_RS17955	COG2814	Major facilitator Superfamily
L3V45_RS17960	COG0833	amino acid
L3V45_RS17965	COG4187	Peptidase family M20/M25/M40
L3V45_RS17970	COG1012	belongs to the aldehyde dehydrogenase family
L3V45_RS17975	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L3V45_RS17985	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
L3V45_RS17990	COG1091	dTDP-4-dehydrorhamnose reductase activity
L3V45_RS17995	COG1088	dTDP-glucose 4,6-dehydratase activity
L3V45_RS18000	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
L3V45_RS18005	COG3980	spore coat polysaccharide biosynthesis protein
L3V45_RS18010	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
L3V45_RS18015	COG2089	acid synthase
L3V45_RS18020	COG0456	acetyltransferase
L3V45_RS18025	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
L3V45_RS18030	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
L3V45_RS18035	COG0463	Glycosyl transferase, family 2
L3V45_RS18045	COG2363	Small membrane protein
L3V45_RS18050	COG2233	PERMEase
L3V45_RS18065	COG1216	Glycosyl transferase, family 2
L3V45_RS18080	COG1695	Transcriptional regulator
L3V45_RS18085	COG0351	phosphomethylpyrimidine kinase
L3V45_RS18095	COG1621	beta-fructofuranosidase activity
L3V45_RS18100	COG1263	PTS System
L3V45_RS18100	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L3V45_RS18105	COG3711	transcriptional antiterminator
L3V45_RS18115	COG1404	Belongs to the peptidase S8 family
L3V45_RS18120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L3V45_RS18125	COG0778	Nitroreductase
L3V45_RS18130	COG0772	Belongs to the SEDS family
L3V45_RS18135	COG0454	-acetyltransferase
L3V45_RS18155	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
L3V45_RS18160	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
L3V45_RS18165	COG2261	transglycosylase associated protein
L3V45_RS18170	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
L3V45_RS18175	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
L3V45_RS18180	COG2246	polysaccharide biosynthetic process
L3V45_RS18185	COG1309	transcriptional regulator
L3V45_RS18205	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
L3V45_RS18210	COG2837	iron assimilation
L3V45_RS18230	COG0583	DNA-binding transcription factor activity
L3V45_RS18240	COG1346	cytolysis
L3V45_RS18245	COG4895	conserved protein (DUF2196)
L3V45_RS18250	COG0789	Transcriptional regulator
L3V45_RS18255	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
L3V45_RS18260	COG0346	lactoylglutathione lyase activity
L3V45_RS18265	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
L3V45_RS18270	COG1404	Belongs to the peptidase S8 family
L3V45_RS18275	COG1442	glycosyl transferase family 8
L3V45_RS18280	COG2357	RelA SpoT domain protein
L3V45_RS18285	COG1575	Belongs to the MenA family. Type 1 subfamily
L3V45_RS18300	COG1696	Membrane protein involved in D-alanine export
L3V45_RS18310	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
L3V45_RS18315	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L3V45_RS18320	COG1486	melibiose metabolic process
L3V45_RS18325	COG1447	Phosphotransferase system cellobiose-specific component IIA
L3V45_RS18330	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
L3V45_RS18335	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
L3V45_RS18340	COG3711	transcriptional antiterminator
L3V45_RS18340	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
L3V45_RS18350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L3V45_RS18355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L3V45_RS18365	COG0640	Transcriptional regulator
L3V45_RS18370	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
L3V45_RS18375	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
L3V45_RS18380	COG1447	Phosphotransferase system cellobiose-specific component IIA
L3V45_RS18385	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
L3V45_RS18390	COG2723	6-phospho-beta-galactosidase activity
L3V45_RS18395	COG1940	carbohydrate kinase activity
L3V45_RS18400	COG1482	cell wall glycoprotein biosynthetic process
L3V45_RS18410	COG0753	catalase activity
L3V45_RS18415	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
L3V45_RS18420	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L3V45_RS18440	COG3279	Response regulator of the LytR AlgR family
L3V45_RS18460	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
L3V45_RS18465	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
L3V45_RS18470	COG4988	ABC transporter
L3V45_RS18475	COG1294	oxidase, subunit
L3V45_RS18480	COG1271	oxidase subunit
L3V45_RS18485	COG3493	citrate carrier protein
L3V45_RS18490	COG0726	polysaccharide deacetylase
L3V45_RS18495	COG3842	ATPase activity
L3V45_RS18500	COG2508	Transcriptional regulator
L3V45_RS18505	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L3V45_RS18515	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L3V45_RS18530	COG4894	glucomannan catabolic process
L3V45_RS18535	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
L3V45_RS18540	COG0500	methyltransferase
L3V45_RS18545	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L3V45_RS18560	COG0753	catalase activity
L3V45_RS18560	COG0693	protein deglycase activity
L3V45_RS18565	COG2851	Citrate transporter
L3V45_RS18570	COG2273	Hydrolase Family 16
L3V45_RS18580	COG2270	Major facilitator Superfamily
L3V45_RS18585	COG0513	Belongs to the DEAD box helicase family
L3V45_RS18655	COG0697	spore germination
L3V45_RS18660	COG0589	response to stress
L3V45_RS18675	COG3507	Belongs to the glycosyl hydrolase 43 family
L3V45_RS18700	COG0010	Belongs to the arginase family
L3V45_RS18705	COG0833	amino acid
L3V45_RS18710	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
L3V45_RS18715	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L3V45_RS18725	COG2390	Transcriptional regulator
L3V45_RS18730	COG0561	phosphatase activity
L3V45_RS18760	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
L3V45_RS18765	COG5294	Protein conserved in bacteria
L3V45_RS18770	COG0577	efflux transmembrane transporter activity
L3V45_RS18775	COG1136	(ABC) transporter
L3V45_RS18780	COG2205	protein histidine kinase activity
L3V45_RS18785	COG0745	RESPONSE REGULATOR receiver
L3V45_RS18800	COG1082	Xylose isomerase domain protein TIM barrel
L3V45_RS18810	COG2814	Major facilitator Superfamily
L3V45_RS18840	COG1349	DNA-binding transcription factor activity
L3V45_RS18845	COG0667	Aldo Keto reductase
L3V45_RS18850	COG2814	Major facilitator Superfamily
L3V45_RS18865	COG1028	Short-chain dehydrogenase reductase Sdr
L3V45_RS18870	COG2197	response regulator
L3V45_RS18875	COG4585	Histidine kinase
L3V45_RS18880	COG3239	Fatty acid desaturase
L3V45_RS18885	COG1309	transcriptional regulator
L3V45_RS18890	COG1012	belongs to the aldehyde dehydrogenase family
L3V45_RS18895	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
L3V45_RS18905	COG0640	Transcriptional regulator
L3V45_RS18910	COG2814	Major facilitator Superfamily
L3V45_RS18915	COG1714	RDD family
L3V45_RS18925	COG0450	alkyl hydroperoxide reductase
L3V45_RS18930	COG3634	alkyl hydroperoxide reductase activity
L3V45_RS18935	COG1113	amino acid transport
L3V45_RS18945	COG2080	2 iron, 2 sulfur cluster binding
L3V45_RS18960	COG2068	MobA-Related Protein
L3V45_RS18965	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
L3V45_RS19020	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
L3V45_RS19025	COG0667	Aldo Keto reductase
L3V45_RS19030	COG0456	acetyltransferase
L3V45_RS19035	COG0457	Tetratricopeptide repeat
L3V45_RS19040	COG0010	Belongs to the arginase family
L3V45_RS19045	COG0833	amino acid
L3V45_RS19050	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L3V45_RS19055	COG3829	transcription factor binding
L3V45_RS19065	COG0488	(ABC) transporter
L3V45_RS19080	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
L3V45_RS19085	COG5002	protein histidine kinase activity
L3V45_RS19095	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L3V45_RS19100	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
L3V45_RS19105	COG4853	Protein conserved in bacteria
L3V45_RS19110	COG4863	YycH protein
L3V45_RS19115	COG5002	protein histidine kinase activity
L3V45_RS19120	COG0745	RESPONSE REGULATOR receiver
L3V45_RS19150	COG0346	lactoylglutathione lyase activity
L3V45_RS19155	COG0305	Participates in initiation and elongation during chromosome replication
L3V45_RS19170	COG3093	addiction module antidote protein HigA
L3V45_RS19175	COG0297	glycogen (starch) synthase activity
L3V45_RS19185	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
L3V45_RS19190	COG0438	transferase activity, transferring glycosyl groups
L3V45_RS19200	COG0515	serine threonine protein kinase
L3V45_RS19210	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
L3V45_RS19215	COG4241	membrane
L3V45_RS19225	COG5577	PFAM Coat F domain
L3V45_RS19230	COG1733	regulation of RNA biosynthetic process
L3V45_RS19240	COG0697	spore germination
L3V45_RS19245	COG1621	beta-fructofuranosidase activity
L3V45_RS19250	COG1621	beta-fructofuranosidase activity
L3V45_RS19255	COG1802	Transcriptional regulator
L3V45_RS19260	COG2318	DinB family
L3V45_RS19265	COG2211	Major facilitator Superfamily
L3V45_RS19275	COG0778	Nitroreductase
L3V45_RS19280	COG1846	Transcriptional regulator
L3V45_RS19285	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L3V45_RS19290	COG1846	Transcriptional regulator
L3V45_RS19310	COG0583	DNA-binding transcription factor activity
L3V45_RS19315	COG1028	Short-chain dehydrogenase reductase Sdr
L3V45_RS19320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L3V45_RS19325	COG0697	spore germination
L3V45_RS19335	COG1959	2 iron, 2 sulfur cluster binding
L3V45_RS19340	COG1396	sequence-specific DNA binding
L3V45_RS19350	COG1331	Highly conserved protein containing a thioredoxin domain
L3V45_RS19355	COG1266	CAAX protease self-immunity
L3V45_RS19360	COG2814	Major facilitator Superfamily
L3V45_RS19360	COG0477	Major facilitator Superfamily
L3V45_RS19365	COG0346	lactoylglutathione lyase activity
L3V45_RS19370	COG1609	Transcriptional regulator
L3V45_RS19375	COG0708	Exodeoxyribonuclease III
L3V45_RS19380	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L3V45_RS19385	COG2169	Transcriptional regulator
L3V45_RS19395	COG0629	single-stranded DNA binding
L3V45_RS19405	COG0012	GTP binding
L3V45_RS19410	COG0243	molybdopterin cofactor binding
L3V45_RS19415	COG4481	Protein conserved in bacteria
L3V45_RS19420	COG3949	Membrane
L3V45_RS19435	COG1475	DNA binding
L3V45_RS19440	COG1192	Involved in chromosome partitioning
L3V45_RS19465	COG1847	R3H domain protein
L3V45_RS19470	COG0706	membrane insertase activity