locus-tag	class	description
DN405_RS00010	COG0592	DNA-directed DNA polymerase activity
DN405_RS00015	COG2501	S4 domain
DN405_RS00025	COG0187	DNA topoisomerase II activity
DN405_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DN405_RS00065	COG0517	IMP dehydrogenase activity
DN405_RS00065	COG0516	GMP reductase activity
DN405_RS00070	COG1686	Belongs to the peptidase S11 family
DN405_RS00100	COG1428	Deoxynucleoside kinase
DN405_RS00105	COG1428	Deoxynucleoside kinase
DN405_RS00110	COG1335	isochorismatase
DN405_RS00120	COG0590	tRNA wobble adenosine to inosine editing
DN405_RS00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DN405_RS00185	COG1982	Orn Lys Arg decarboxylase major
DN405_RS00195	COG0470	DNA polymerase III
DN405_RS00200	COG1774	PSP1 C-terminal conserved region
DN405_RS00210	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DN405_RS00220	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DN405_RS00225	COG2002	toxin-antitoxin pair type II binding
DN405_RS00235	COG0084	hydrolase, TatD family'
DN405_RS00255	COG4466	Protein conserved in bacteria
DN405_RS00270	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DN405_RS00275	COG0251	oxidation-reduction process
DN405_RS00305	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DN405_RS00310	COG2002	toxin-antitoxin pair type II binding
DN405_RS00315	COG2244	polysaccharide biosynthetic process
DN405_RS00320	COG3956	TIGRFAM MazG family protein
DN405_RS00325	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DN405_RS00345	COG1098	S1 RNA binding domain
DN405_RS00360	COG2208	phosphoserine phosphatase activity
DN405_RS00370	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DN405_RS00375	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DN405_RS00390	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DN405_RS00395	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DN405_RS00400	COG0512	Glutamine amidotransferase of anthranilate synthase
DN405_RS00405	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DN405_RS00410	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DN405_RS00415	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DN405_RS00420	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DN405_RS00425	COG1396	sequence-specific DNA binding
DN405_RS00430	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DN405_RS00520	COG3880	PFAM UvrB UvrC protein
DN405_RS00530	COG0542	response to heat
DN405_RS00535	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DN405_RS00545	COG4956	integral membrane protein (PIN domain superfamily)
DN405_RS00565	COG1045	serine acetyltransferase
DN405_RS00580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DN405_RS00585	COG3688	RNA-binding protein containing a PIN domain
DN405_RS00600	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DN405_RS00605	COG0250	Participates in transcription elongation, termination and antitermination
DN405_RS00610	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DN405_RS00630	COG2813	Specifically methylates the guanine in position
DN405_RS00645	COG1358	cellular component organization or biogenesis
DN405_RS00650	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DN405_RS00720	COG0255	Belongs to the universal ribosomal protein uL29 family
DN405_RS00780	COG0201	protein transport
DN405_RS00790	COG0024	Methionine aminopeptidase
DN405_RS00800	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DN405_RS00835	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DN405_RS00860	COG0860	N-Acetylmuramoyl-L-alanine amidase
DN405_RS00865	COG0489	protein tyrosine kinase activity
DN405_RS00875	COG2194	sulfuric ester hydrolase activity
DN405_RS00880	COG0726	polysaccharide deacetylase
DN405_RS00960	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DN405_RS00965	COG4856	YbbR-like protein
DN405_RS01005	COG1028	Short-chain dehydrogenase reductase Sdr
DN405_RS01010	COG2011	ABC-type metal ion transport system permease component
DN405_RS01015	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DN405_RS01020	COG1464	Belongs to the NlpA lipoprotein family
DN405_RS01025	COG0604	alcohol dehydrogenase
DN405_RS01035	COG0277	FAD linked oxidase domain protein
DN405_RS01040	COG2271	Major facilitator Superfamily
DN405_RS01050	COG2814	Major facilitator Superfamily
DN405_RS01065	COG0601	transmembrane transport
DN405_RS01070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DN405_RS01075	COG0444	Belongs to the ABC transporter superfamily
DN405_RS01080	COG4608	Belongs to the ABC transporter superfamily
DN405_RS01085	COG4166	transmembrane transport
DN405_RS01095	COG2207	Transcriptional regulator
DN405_RS01110	COG4166	transmembrane transport
DN405_RS01115	COG4166	transmembrane transport
DN405_RS01120	COG0656	L-ascorbic acid biosynthetic process
DN405_RS01135	COG4149	molybdate abc transporter
DN405_RS01140	COG0725	ABC transporter, periplasmic molybdate-binding protein
DN405_RS01145	COG1910	domain protein
DN405_RS01160	COG0697	spore germination
DN405_RS01175	COG0204	Acyl-transferase
DN405_RS01185	COG1609	Transcriptional regulator
DN405_RS01195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DN405_RS01210	COG5298	Protein conserved in bacteria
DN405_RS01230	COG0488	(ABC) transporter
DN405_RS01245	COG0747	negative chemotaxis
DN405_RS01250	COG0601	transmembrane transport
DN405_RS01255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DN405_RS01260	COG0444	Belongs to the ABC transporter superfamily
DN405_RS01265	COG4608	Belongs to the ABC transporter superfamily
DN405_RS01270	COG0561	phosphatase activity
DN405_RS01300	COG3185	4-Hydroxyphenylpyruvate dioxygenase
DN405_RS01305	COG0179	Fumarylacetoacetate (FAA) hydrolase
DN405_RS01315	COG0531	amino acid
DN405_RS01320	COG2814	Major facilitator Superfamily
DN405_RS01330	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DN405_RS01340	COG4294	response to UV
DN405_RS01345	COG0705	Rhomboid family
DN405_RS01355	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DN405_RS01360	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DN405_RS01365	COG0864	Transcriptional regulator
DN405_RS01370	COG2337	Toxic component of a toxin-antitoxin (TA) module
DN405_RS01375	COG2183	response to ionizing radiation
DN405_RS01475	COG0802	atpase or kinase
DN405_RS01480	COG1214	PFAM Peptidase M22, glycoprotease
DN405_RS01485	COG0456	acetyltransferase
DN405_RS01495	COG0488	(ABC) transporter
DN405_RS01510	COG1266	CAAX protease self-immunity
DN405_RS01530	COG2252	PERMEase
DN405_RS01540	COG5002	protein histidine kinase activity
DN405_RS01570	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DN405_RS01615	COG2205	protein histidine kinase activity
DN405_RS01620	COG0745	RESPONSE REGULATOR receiver
DN405_RS01650	COG2226	methyltransferase
DN405_RS01660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DN405_RS01670	COG0463	Glycosyl transferase, family 2
DN405_RS01670	COG1216	Glycosyl transferase, family 2
DN405_RS01690	COG0697	spore germination
DN405_RS01720	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DN405_RS01725	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DN405_RS01730	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DN405_RS01740	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DN405_RS01755	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DN405_RS01765	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DN405_RS01775	COG0151	Belongs to the GarS family
DN405_RS01805	COG0210	DNA helicase
DN405_RS01815	COG4851	CamS sex pheromone cAM373 precursor
DN405_RS01830	COG1335	isochorismatase
DN405_RS01840	COG2011	ABC-type metal ion transport system permease component
DN405_RS01845	COG1464	Belongs to the NlpA lipoprotein family
DN405_RS01860	COG0003	Pfam Anion-transporting ATPase
DN405_RS01865	COG1846	Transcriptional regulator
DN405_RS01870	COG4682	membrane
DN405_RS01890	COG1597	lipid kinase activity
DN405_RS01900	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DN405_RS01910	COG1012	belongs to the aldehyde dehydrogenase family
DN405_RS01915	COG2076	Multidrug Resistance protein
DN405_RS01925	COG2309	aminopeptidase activity
DN405_RS01940	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DN405_RS01950	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DN405_RS01955	COG4807	Protein conserved in bacteria
DN405_RS01985	COG1757	Na H antiporter
DN405_RS01990	COG1473	amidohydrolase
DN405_RS02005	COG0450	alkyl hydroperoxide reductase
DN405_RS02025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DN405_RS02030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DN405_RS02035	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DN405_RS02045	COG0492	ferredoxin-NADP+ reductase activity
DN405_RS02060	COG0166	Belongs to the GPI family
DN405_RS02085	COG5002	protein histidine kinase activity
DN405_RS02105	COG3541	Predicted nucleotidyltransferase
DN405_RS02110	COG2814	Major facilitator Superfamily
DN405_RS02115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DN405_RS02115	COG0723	plastoquinol--plastocyanin reductase activity
DN405_RS02125	COG0765	amino acid transport
DN405_RS02130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DN405_RS02140	COG0840	transmembrane signaling receptor activity
DN405_RS02165	COG0549	Belongs to the carbamate kinase family
DN405_RS02170	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DN405_RS02180	COG0277	FAD linked oxidase domain protein
DN405_RS02185	COG0366	Alpha amylase catalytic
DN405_RS02190	COG1263	PTS System
DN405_RS02190	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DN405_RS02190	COG2190	(PTS) system
DN405_RS02220	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
DN405_RS02240	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DN405_RS02245	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DN405_RS02250	COG1116	anion transmembrane transporter activity
DN405_RS02305	COG2270	Major facilitator Superfamily
DN405_RS02340	COG2310	stress, protein
DN405_RS02345	COG2310	stress, protein
DN405_RS02350	COG2310	stress, protein
DN405_RS02355	COG0861	Integral membrane protein TerC family
DN405_RS02365	COG3853	Toxic anion resistance protein (TelA)
DN405_RS02380	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DN405_RS02390	COG1295	ribonuclease BN
DN405_RS02395	COG2217	Heavy metal translocating P-type atpase
DN405_RS02400	COG0697	spore germination
DN405_RS02420	COG0586	Pfam SNARE associated Golgi protein
DN405_RS02435	COG3871	stress protein (general stress protein 26)
DN405_RS02440	COG0387	Pfam Sodium calcium exchanger
DN405_RS02450	COG0535	radical SAM domain protein
DN405_RS02470	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DN405_RS02475	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DN405_RS02490	COG3829	transcription factor binding
DN405_RS02500	COG0833	amino acid
DN405_RS02505	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DN405_RS02535	COG1263	PTS System
DN405_RS02535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DN405_RS02540	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DN405_RS02555	COG0463	Glycosyl transferase, family 2
DN405_RS02565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DN405_RS02565	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DN405_RS02585	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DN405_RS02605	COG1228	amidohydrolase
DN405_RS02610	COG1090	epimerase
DN405_RS02640	COG1988	membrane-bound metal-dependent
DN405_RS02645	COG1194	a g-specific adenine glycosylase
DN405_RS02670	COG1132	(ABC) transporter
DN405_RS02675	COG4129	membrane
DN405_RS02680	COG0069	glutamate synthase activity
DN405_RS02680	COG0070	glutamate synthase
DN405_RS02680	COG0067	glutamate synthase
DN405_RS02690	COG4555	ABC transporter
DN405_RS02710	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DN405_RS02715	COG0735	belongs to the Fur family
DN405_RS02835	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DN405_RS02860	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DN405_RS02870	COG2766	serine protein kinase
DN405_RS02890	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DN405_RS02900	COG1585	Membrane protein implicated in regulation of membrane protease activity
DN405_RS02905	COG2268	Band 7 protein
DN405_RS02915	COG3290	protein histidine kinase activity
DN405_RS02920	COG4565	transcriptional regulatory protein
DN405_RS02925	COG2851	Citrate transporter
DN405_RS02950	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
DN405_RS02955	COG3842	ATPase activity
DN405_RS02960	COG1175	transmembrane transport
DN405_RS02965	COG0395	ABC-type sugar transport system, permease component
DN405_RS02975	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DN405_RS02980	COG0745	RESPONSE REGULATOR receiver
DN405_RS02985	COG5002	protein histidine kinase activity
DN405_RS02985	COG3850	Histidine kinase
DN405_RS02995	COG4990	cell redox homeostasis
DN405_RS03005	COG3290	protein histidine kinase activity
DN405_RS03010	COG4565	transcriptional regulatory protein
DN405_RS03015	COG3493	citrate carrier protein
DN405_RS03020	COG0281	malic enzyme
DN405_RS03030	COG0697	spore germination
DN405_RS03035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DN405_RS03045	COG5002	protein histidine kinase activity
DN405_RS03055	COG0456	acetyltransferase
DN405_RS03055	COG0454	-acetyltransferase
DN405_RS03060	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DN405_RS03065	COG3383	formate dehydrogenase (NAD+) activity
DN405_RS03070	COG2427	Protein of unknown function (DUF1641)
DN405_RS03085	COG0531	amino acid
DN405_RS03095	COG0640	Transcriptional regulator
DN405_RS03100	COG2217	Heavy metal translocating P-type atpase
DN405_RS03105	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DN405_RS03120	COG3227	Zinc metalloprotease (Elastase)
DN405_RS03140	COG2720	vancomycin resistance protein
DN405_RS03145	COG1316	TRANSCRIPTIONal
DN405_RS03150	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DN405_RS03155	COG0346	lactoylglutathione lyase activity
DN405_RS03160	COG1253	flavin adenine dinucleotide binding
DN405_RS03165	COG1027	Aspartate ammonia-lyase
DN405_RS03170	COG1620	l-lactate permease
DN405_RS03185	COG3104	oligopeptide transport
DN405_RS03190	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DN405_RS03195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DN405_RS03200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DN405_RS03210	COG2226	methyltransferase
DN405_RS03220	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DN405_RS03230	COG4548	von Willebrand factor, type A
DN405_RS03235	COG0714	Associated with various cellular activities
DN405_RS03255	COG0531	amino acid
DN405_RS03260	COG2188	Transcriptional regulator
DN405_RS03265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DN405_RS03265	COG1263	PTS System
DN405_RS03270	COG0366	Alpha amylase catalytic
DN405_RS03285	COG0697	spore germination
DN405_RS03290	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DN405_RS03295	COG1115	amino acid carrier protein
DN405_RS03305	COG1126	abc transporter atp-binding protein
DN405_RS03310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DN405_RS03315	COG0765	amino acid transport
DN405_RS03320	COG0765	amino acid transport
DN405_RS03325	COG0833	amino acid
DN405_RS03340	COG2378	regulation of single-species biofilm formation
DN405_RS03345	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DN405_RS03350	COG5002	protein histidine kinase activity
DN405_RS03375	COG0659	secondary active sulfate transmembrane transporter activity
DN405_RS03390	COG2271	Major facilitator Superfamily
DN405_RS03395	COG1846	Transcriptional regulator
DN405_RS03400	COG0477	Major facilitator Superfamily
DN405_RS03405	COG1609	Transcriptional regulator
DN405_RS03410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DN405_RS03425	COG1172	Belongs to the binding-protein-dependent transport system permease family
DN405_RS03430	COG1879	ABC-type sugar transport system periplasmic component
DN405_RS03455	COG1063	alcohol dehydrogenase
DN405_RS03505	COG0840	transmembrane signaling receptor activity
DN405_RS03510	COG3584	3D domain protein
DN405_RS03510	COG3583	domain protein
DN405_RS03515	COG1476	TRANSCRIPTIONal
DN405_RS03535	COG3104	oligopeptide transport
DN405_RS03540	COG1114	Component of the transport system for branched-chain amino acids
DN405_RS03555	COG1113	amino acid transport
DN405_RS03560	COG2252	PERMEase
DN405_RS03575	COG2153	protein acetylation
DN405_RS03585	COG0475	glutathione-regulated potassium exporter activity
DN405_RS03585	COG0569	domain protein
DN405_RS03595	COG1845	cytochrome c oxidase, subunit III
DN405_RS03600	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DN405_RS03610	COG0833	amino acid
DN405_RS03615	COG4990	cell redox homeostasis
DN405_RS03630	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DN405_RS03635	COG0697	spore germination
DN405_RS03640	COG0531	amino acid
DN405_RS03650	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DN405_RS03655	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DN405_RS03660	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DN405_RS03660	COG1918	ferrous iron import across plasma membrane
DN405_RS03665	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DN405_RS03670	COG0573	inorganic phosphate transmembrane transporter activity
DN405_RS03675	COG0581	inorganic phosphate transmembrane transporter activity
DN405_RS03685	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DN405_RS03805	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
DN405_RS03825	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DN405_RS03830	COG1116	anion transmembrane transporter activity
DN405_RS03835	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DN405_RS03840	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DN405_RS03845	COG0352	thiamine-phosphate diphosphorylase activity
DN405_RS03850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DN405_RS03855	COG2104	thiamine diphosphate biosynthetic process
DN405_RS03865	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DN405_RS03870	COG0351	phosphomethylpyrimidine kinase
DN405_RS03910	COG2205	protein histidine kinase activity
DN405_RS03915	COG2814	Major facilitator Superfamily
DN405_RS03920	COG1846	Transcriptional regulator
DN405_RS03930	COG2252	PERMEase
DN405_RS03935	COG1028	Short-chain dehydrogenase reductase Sdr
DN405_RS03950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DN405_RS03955	COG1621	beta-fructofuranosidase activity
DN405_RS03960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DN405_RS03960	COG1263	PTS System
DN405_RS03965	COG1609	Transcriptional regulator
DN405_RS04015	COG0778	Nitroreductase
DN405_RS04020	COG2719	SpoVR family
DN405_RS04030	COG3591	Belongs to the peptidase S1B family
DN405_RS04055	COG0446	pyridine nucleotide-disulphide oxidoreductase
DN405_RS04060	COG1937	Protein conserved in bacteria
DN405_RS04065	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DN405_RS04065	COG0425	Belongs to the sulfur carrier protein TusA family
DN405_RS04070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN405_RS04070	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DN405_RS04075	COG0425	Belongs to the sulfur carrier protein TusA family
DN405_RS04080	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DN405_RS04080	COG0425	Belongs to the sulfur carrier protein TusA family
DN405_RS04085	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DN405_RS04090	COG2210	Belongs to the sulfur carrier protein TusA family
DN405_RS04095	COG0730	response to heat
DN405_RS04105	COG1316	TRANSCRIPTIONal
DN405_RS04110	COG0604	alcohol dehydrogenase
DN405_RS04115	COG1283	sodium-dependent phosphate transmembrane transporter activity
DN405_RS04135	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DN405_RS04135	COG3711	transcriptional antiterminator
DN405_RS04140	COG1447	Phosphotransferase system cellobiose-specific component IIA
DN405_RS04145	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DN405_RS04170	COG1388	LysM domain
DN405_RS04170	COG3584	3D domain protein
DN405_RS04175	COG0577	efflux transmembrane transporter activity
DN405_RS04180	COG1136	(ABC) transporter
DN405_RS04190	COG5522	Integral membrane protein (intg_mem_TP0381)
DN405_RS04205	COG1114	Component of the transport system for branched-chain amino acids
DN405_RS04210	COG3546	catalase activity
DN405_RS04245	COG0586	Pfam SNARE associated Golgi protein
DN405_RS04275	COG0531	amino acid
DN405_RS04280	COG0475	glutathione-regulated potassium exporter activity
DN405_RS04290	COG1737	Transcriptional regulator
DN405_RS04300	COG1263	PTS System
DN405_RS04300	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DN405_RS04310	COG2259	Doxx family
DN405_RS04330	COG1522	sequence-specific DNA binding
DN405_RS04335	COG0165	Argininosuccinate lyase
DN405_RS04335	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DN405_RS04340	COG0300	oxidoreductase activity
DN405_RS04365	COG1309	transcriptional regulator
DN405_RS04370	COG2814	Major facilitator Superfamily
DN405_RS04375	COG1733	regulation of RNA biosynthetic process
DN405_RS04390	COG4533	DNA binding
DN405_RS04395	COG2211	Major facilitator Superfamily
DN405_RS04405	COG0693	protein deglycase activity
DN405_RS04420	COG0531	amino acid
DN405_RS04435	COG1012	belongs to the aldehyde dehydrogenase family
DN405_RS04450	COG1132	(ABC) transporter
DN405_RS04455	COG1132	(ABC) transporter
DN405_RS04465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DN405_RS04470	COG0765	amino acid transport
DN405_RS04475	COG1126	abc transporter atp-binding protein
DN405_RS04490	COG0189	ligase activity
DN405_RS04520	COG0028	Belongs to the TPP enzyme family
DN405_RS04525	COG3527	Alpha-acetolactate decarboxylase
DN405_RS04540	COG0561	phosphatase activity
DN405_RS04550	COG5632	N-Acetylmuramoyl-L-alanine amidase
DN405_RS04550	COG3409	Peptidoglycan-binding domain 1 protein
DN405_RS04555	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DN405_RS04560	COG0318	PFAM AMP-dependent synthetase and ligase
DN405_RS04575	COG0659	secondary active sulfate transmembrane transporter activity
DN405_RS04580	COG2244	polysaccharide biosynthetic process
DN405_RS04605	COG1024	Enoyl-CoA hydratase
DN405_RS04625	COG1363	Peptidase, m42
DN405_RS04660	COG0601	transmembrane transport
DN405_RS04665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DN405_RS04670	COG0444	Belongs to the ABC transporter superfamily
DN405_RS04675	COG4608	Belongs to the ABC transporter superfamily
DN405_RS04685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN405_RS04705	COG0477	Major facilitator Superfamily
DN405_RS04710	COG3290	protein histidine kinase activity
DN405_RS04715	COG4565	transcriptional regulatory protein
DN405_RS04720	COG3181	Tripartite tricarboxylate transporter family receptor
DN405_RS04755	COG0789	Transcriptional regulator
DN405_RS04755	COG4978	Transcriptional regulator
DN405_RS04770	COG0305	Participates in initiation and elongation during chromosome replication
DN405_RS04795	COG0477	Major facilitator Superfamily
DN405_RS04810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DN405_RS04835	COG1073	alpha beta
DN405_RS04875	COG1183	phosphatidylcholine synthase activity
DN405_RS04895	COG2376	Dihydroxyacetone kinase
DN405_RS04910	COG2376	Dihydroxyacetone kinase
DN405_RS04950	COG2373	Large extracellular alpha-helical protein
DN405_RS04970	COG0596	Alpha beta hydrolase
DN405_RS05040	COG1191	sigma factor activity
DN405_RS05050	COG2208	phosphoserine phosphatase activity
DN405_RS05055	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DN405_RS05060	COG5002	protein histidine kinase activity
DN405_RS05060	COG0784	Response regulator, receiver
DN405_RS05060	COG2205	protein histidine kinase activity
DN405_RS05100	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
DN405_RS05120	COG0420	3'-5' exonuclease activity
DN405_RS05125	COG4717	serine-type aminopeptidase activity
DN405_RS05135	COG0346	lactoylglutathione lyase activity
DN405_RS05140	COG0346	lactoylglutathione lyase activity
DN405_RS05145	COG0457	Tetratricopeptide repeat
DN405_RS05160	COG2267	carboxylic ester hydrolase activity
DN405_RS05175	COG2140	Oxalate decarboxylase
DN405_RS05180	COG3620	sequence-specific DNA binding
DN405_RS05185	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
DN405_RS05190	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DN405_RS05200	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DN405_RS05205	COG1695	Transcriptional regulator
DN405_RS05220	COG1595	DNA-templated transcription, initiation
DN405_RS05240	COG2409	Drug exporters of the RND superfamily
DN405_RS05240	COG1033	growth of symbiont in host cell
DN405_RS05245	COG3973	AAA domain
DN405_RS05280	COG4980	gas vesicle protein
DN405_RS05285	COG0537	adenosine 5'-monophosphoramidase activity
DN405_RS05290	COG1131	(ABC) transporter
DN405_RS05295	COG4473	ABC transporter
DN405_RS05315	COG3402	PFAM membrane-flanked domain
DN405_RS05320	COG3428	Bacterial PH domain
DN405_RS05360	COG0697	spore germination
DN405_RS05365	COG3402	PFAM membrane-flanked domain
DN405_RS05370	COG3428	Bacterial PH domain
DN405_RS05375	COG2329	Antibiotic biosynthesis monooxygenase
DN405_RS05380	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DN405_RS05395	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DN405_RS05420	COG1309	transcriptional regulator
DN405_RS05425	COG1511	domain protein
DN405_RS05455	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DN405_RS05460	COG1609	Transcriptional regulator
DN405_RS05470	COG1234	tRNA 3'-trailer cleavage
DN405_RS05475	COG0095	Lipoate-protein ligase
DN405_RS05485	COG0318	PFAM AMP-dependent synthetase and ligase
DN405_RS05495	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DN405_RS05505	COG4208	sulfate ABC transporter
DN405_RS05585	COG1408	metallophosphoesterase
DN405_RS05590	COG1078	dGTPase activity
DN405_RS05600	COG1595	DNA-templated transcription, initiation
DN405_RS05605	COG3708	Transcriptional regulator
DN405_RS05605	COG2207	Transcriptional regulator
DN405_RS05610	COG2205	protein histidine kinase activity
DN405_RS05615	COG0745	RESPONSE REGULATOR receiver
DN405_RS05635	COG0501	Belongs to the peptidase M48B family
DN405_RS05640	COG0840	transmembrane signaling receptor activity
DN405_RS05645	COG3693	PFAM glycoside hydrolase, family 10
DN405_RS05655	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DN405_RS05660	COG2224	Isocitrate lyase
DN405_RS05675	COG1278	Cold shock
DN405_RS05695	COG0398	Pfam SNARE associated Golgi protein
DN405_RS05755	COG0179	Fumarylacetoacetate (FAA) hydrolase
DN405_RS05780	COG0367	asparagine synthase
DN405_RS05790	COG0753	catalase activity
DN405_RS05795	COG0004	ammonium transporteR
DN405_RS05820	COG2996	Protein conserved in bacteria
DN405_RS05835	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DN405_RS05850	COG0561	phosphatase activity
DN405_RS05870	COG2267	carboxylic ester hydrolase activity
DN405_RS05890	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DN405_RS05895	COG5504	Zn-dependent protease
DN405_RS05910	COG0180	Tryptophanyl-tRNA synthetase
DN405_RS05925	COG4166	transmembrane transport
DN405_RS05930	COG0601	transmembrane transport
DN405_RS05935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DN405_RS05940	COG0444	Belongs to the ABC transporter superfamily
DN405_RS05945	COG4608	Belongs to the ABC transporter superfamily
DN405_RS05950	COG0534	Mate efflux family protein
DN405_RS05955	COG4166	transmembrane transport
DN405_RS05970	COG0861	Integral membrane protein TerC family
DN405_RS05990	COG1164	Oligoendopeptidase f
DN405_RS06000	COG2346	COG2346, Truncated hemoglobins
DN405_RS06005	COG4116	CYTH
DN405_RS06015	COG2357	RelA SpoT domain protein
DN405_RS06025	COG0564	pseudouridine synthase activity
DN405_RS06040	COG0772	Belongs to the SEDS family
DN405_RS06045	COG1216	Glycosyl transferase, family 2
DN405_RS06065	COG0463	Glycosyl transferase, family 2
DN405_RS06065	COG0457	Tetratricopeptide repeat
DN405_RS06085	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DN405_RS06100	COG1091	dTDP-4-dehydrorhamnose reductase activity
DN405_RS06145	COG2153	protein acetylation
DN405_RS06155	COG2382	esterase
DN405_RS06180	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DN405_RS06190	COG0512	Glutamine amidotransferase of anthranilate synthase
DN405_RS06190	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DN405_RS06225	COG1620	l-lactate permease
DN405_RS06230	COG5634	Uncharacterized conserved protein (DUF2278)
DN405_RS06280	COG0508	dehydrogenase complex catalyzes the overall conversion of
DN405_RS06290	COG1476	TRANSCRIPTIONal
DN405_RS06345	COG1686	Belongs to the peptidase S11 family
DN405_RS06350	COG0681	Belongs to the peptidase S26 family
DN405_RS06385	COG1012	belongs to the aldehyde dehydrogenase family
DN405_RS06395	COG1176	ABC-type spermidine putrescine transport system, permease component I
DN405_RS06400	COG1177	transmembrane transport
DN405_RS06415	COG2409	Drug exporters of the RND superfamily
DN405_RS06425	COG0564	pseudouridine synthase activity
DN405_RS06435	COG2340	Cysteine-rich secretory protein family
DN405_RS06440	COG0247	lactate metabolic process
DN405_RS06445	COG0277	FAD linked oxidase domain protein
DN405_RS06450	COG3835	regulator
DN405_RS06460	COG0745	RESPONSE REGULATOR receiver
DN405_RS06465	COG5002	protein histidine kinase activity
DN405_RS06470	COG2186	Transcriptional regulator
DN405_RS06490	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DN405_RS06500	COG2116	formate transmembrane transporter activity
DN405_RS06505	COG0861	Integral membrane protein TerC family
DN405_RS06510	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DN405_RS06520	COG2030	dehydratase
DN405_RS06540	COG1028	Short-chain dehydrogenase reductase Sdr
DN405_RS06545	COG3243	poly(R)-hydroxyalkanoic acid synthase
DN405_RS06555	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DN405_RS06570	COG1840	ABC-type Fe3 transport system, periplasmic component
DN405_RS06575	COG3842	ATPase activity
DN405_RS06600	COG1349	DNA-binding transcription factor activity
DN405_RS06610	COG0235	Class ii aldolase
DN405_RS06620	COG2861	carbohydrate metabolic process
DN405_RS06630	COG3852	Histidine kinase
DN405_RS06635	COG1846	Transcriptional regulator
DN405_RS06645	COG2318	DinB family
DN405_RS06650	COG5002	protein histidine kinase activity
DN405_RS06660	COG0720	synthase
DN405_RS06675	COG4873	Protein conserved in bacteria
DN405_RS06710	COG1780	Probably involved in ribonucleotide reductase function
DN405_RS06715	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DN405_RS06720	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DN405_RS06725	COG1725	Transcriptional regulator
DN405_RS06730	COG1131	(ABC) transporter
DN405_RS06740	COG1131	(ABC) transporter
DN405_RS06745	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DN405_RS06760	COG1522	sequence-specific DNA binding
DN405_RS06770	COG1335	isochorismatase
DN405_RS06780	COG1619	proteins homologs of microcin C7 resistance protein MccF
DN405_RS06785	COG2070	2-Nitropropane dioxygenase
DN405_RS06790	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DN405_RS06800	COG1696	Membrane protein involved in D-alanine export
DN405_RS06820	COG0716	FMN binding
DN405_RS06865	COG1846	Transcriptional regulator
DN405_RS06875	COG1301	dicarboxylic acid transport
DN405_RS06880	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DN405_RS06885	COG4709	membrane
DN405_RS06890	COG3874	Sporulation protein YtfJ
DN405_RS06910	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DN405_RS06915	COG0028	Belongs to the TPP enzyme family
DN405_RS06920	COG0440	acetolactate synthase activity
DN405_RS06995	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DN405_RS07010	COG1183	phosphatidylcholine synthase activity
DN405_RS07015	COG1368	sulfuric ester hydrolase activity
DN405_RS07025	COG0019	diaminopimelate decarboxylase activity
DN405_RS07045	COG0529	Catalyzes the synthesis of activated sulfate
DN405_RS07050	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DN405_RS07070	COG1648	precorrin-2 dehydrogenase activity
DN405_RS07075	COG0733	neurotransmitter:sodium symporter activity
DN405_RS07095	COG1757	Na H antiporter
DN405_RS07110	COG4758	membrane
DN405_RS07115	COG4585	Histidine kinase
DN405_RS07120	COG2197	response regulator
DN405_RS07130	COG1114	Component of the transport system for branched-chain amino acids
DN405_RS07180	COG0730	response to heat
DN405_RS07185	COG0306	phosphate transporter
DN405_RS07190	COG1392	Phosphate transport regulator
DN405_RS07195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DN405_RS07210	COG3852	Histidine kinase
DN405_RS07215	COG1801	Protein of unknown function DUF72
DN405_RS07225	COG0582	viral genome integration into host DNA
DN405_RS07230	COG5002	protein histidine kinase activity
DN405_RS07250	COG0392	lysyltransferase activity
DN405_RS07250	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DN405_RS07265	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DN405_RS07270	COG1686	Belongs to the peptidase S11 family
DN405_RS07275	COG2715	membrane protein required for spore maturation
DN405_RS07280	COG0700	Nucleoside recognition
DN405_RS07285	COG1187	pseudouridine synthase activity
DN405_RS07295	COG1333	cytochrome c biogenesis protein
DN405_RS07300	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DN405_RS07305	COG0745	RESPONSE REGULATOR receiver
DN405_RS07310	COG5002	protein histidine kinase activity
DN405_RS07315	COG2096	Adenosyltransferase
DN405_RS07330	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DN405_RS07335	COG1141	Ferredoxin
DN405_RS07345	COG0514	ATP-dependent DNA helicase (RecQ)
DN405_RS07350	COG1266	CAAX protease self-immunity
DN405_RS07360	COG1408	metallophosphoesterase
DN405_RS07365	COG0789	Transcriptional regulator
DN405_RS07375	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DN405_RS07395	COG0492	ferredoxin-NADP+ reductase activity
DN405_RS07400	COG0252	asparaginase activity
DN405_RS07465	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DN405_RS07480	COG0142	geranyltranstransferase activity
DN405_RS07490	COG0142	geranyltranstransferase activity
DN405_RS07515	COG0457	Tetratricopeptide repeat
DN405_RS07535	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DN405_RS07540	COG2010	Cytochrome c
DN405_RS07540	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DN405_RS07545	COG4347	Protein of unknown function (DUF1405)
DN405_RS07560	COG2738	Putative neutral zinc metallopeptidase
DN405_RS07570	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DN405_RS07580	COG1694	Mazg nucleotide pyrophosphohydrolase
DN405_RS07600	COG0438	transferase activity, transferring glycosyl groups
DN405_RS07635	COG1199	ATP-dependent helicase activity
DN405_RS07635	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DN405_RS07655	COG3935	DnaD domain protein
DN405_RS07660	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DN405_RS07670	COG4499	WXG100 protein secretion system (Wss), protein YukC
DN405_RS07670	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DN405_RS07725	COG0116	Belongs to the methyltransferase superfamily
DN405_RS07735	COG1199	ATP-dependent helicase activity
DN405_RS07740	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
DN405_RS07750	COG0024	Methionine aminopeptidase
DN405_RS07765	COG2233	PERMEase
DN405_RS07770	COG2311	Membrane
DN405_RS07775	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DN405_RS07785	COG0456	acetyltransferase
DN405_RS07820	COG0754	glutathionylspermidine amidase activity
DN405_RS07840	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DN405_RS07855	COG3944	biosynthesis protein
DN405_RS07865	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DN405_RS07880	COG1215	transferase activity, transferring glycosyl groups
DN405_RS07885	COG0438	transferase activity, transferring glycosyl groups
DN405_RS07900	COG0454	-acetyltransferase
DN405_RS07920	COG0328	RNA-DNA hybrid ribonuclease activity
DN405_RS07955	COG3403	YqcI/YcgG family
DN405_RS07960	COG1280	lysine exporter protein (LysE YggA)
DN405_RS07980	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DN405_RS07985	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DN405_RS07995	COG0475	glutathione-regulated potassium exporter activity
DN405_RS08000	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DN405_RS08005	COG4978	Transcriptional regulator
DN405_RS08005	COG0789	Transcriptional regulator
DN405_RS08015	COG2323	membrane
DN405_RS08020	COG1434	Gram-negative-bacterium-type cell wall biogenesis
DN405_RS08055	COG1923	regulation of RNA biosynthetic process
DN405_RS08065	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DN405_RS08070	COG1360	Flagellar Motor Protein
DN405_RS08075	COG2201	protein-glutamate methylesterase activity
DN405_RS08080	COG2198	Histidine kinase
DN405_RS08080	COG0643	Histidine kinase
DN405_RS08085	COG1776	CheC inhibitor of MCP methylation
DN405_RS08085	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DN405_RS08100	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DN405_RS08120	COG1256	bacterial-type flagellum assembly
DN405_RS08125	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DN405_RS08145	COG1815	bacterial-type flagellum-dependent cell motility
DN405_RS08150	COG1558	bacterial-type flagellum-dependent cell motility
DN405_RS08160	COG1766	The M ring may be actively involved in energy transduction
DN405_RS08165	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DN405_RS08175	COG1157	protein secretion by the type III secretion system
DN405_RS08195	COG1749	Flagellar hook protein flgE
DN405_RS08210	COG0784	Response regulator, receiver
DN405_RS08210	COG0835	chemotaxis
DN405_RS08220	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DN405_RS08225	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DN405_RS08230	COG0741	lytic transglycosylase activity
DN405_RS08240	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DN405_RS08245	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DN405_RS08245	COG1776	CheC inhibitor of MCP methylation
DN405_RS08255	COG1338	Plays a role in the flagellum-specific transport system
DN405_RS08260	COG1987	bacterial-type flagellum assembly
DN405_RS08270	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DN405_RS08275	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DN405_RS08280	COG1419	protein localization to endoplasmic reticulum
DN405_RS08285	COG4786	Flagellar basal body rod
DN405_RS08290	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DN405_RS08325	COG2329	Antibiotic biosynthesis monooxygenase
DN405_RS08350	COG0583	DNA-binding transcription factor activity
DN405_RS08370	COG1234	tRNA 3'-trailer cleavage
DN405_RS08400	COG0406	alpha-ribazole phosphatase activity
DN405_RS08430	COG0367	asparagine synthase
DN405_RS08460	COG1802	Transcriptional regulator
DN405_RS08465	COG0697	spore germination
DN405_RS08475	COG0523	cobalamin synthesis protein
DN405_RS08485	COG0701	Predicted permease
DN405_RS08500	COG1757	Na H antiporter
DN405_RS08505	COG0789	Transcriptional regulator
DN405_RS08530	COG0534	Mate efflux family protein
DN405_RS08535	COG3340	Belongs to the peptidase S51 family
DN405_RS08555	COG0785	Cytochrome C biogenesis protein
DN405_RS08560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DN405_RS08580	COG2733	membrane
DN405_RS08610	COG2197	response regulator
DN405_RS08620	COG1131	(ABC) transporter
DN405_RS08640	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DN405_RS08645	COG0528	UMP kinase activity
DN405_RS08655	COG1027	Aspartate ammonia-lyase
DN405_RS08660	COG0281	malic enzyme
DN405_RS08665	COG4191	Histidine kinase
DN405_RS08670	COG0784	Response regulator, receiver
DN405_RS08675	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DN405_RS08725	COG2814	Major facilitator Superfamily
DN405_RS08740	COG1695	Transcriptional regulator
DN405_RS08755	COG0477	Major facilitator Superfamily
DN405_RS08765	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DN405_RS08770	COG2223	nitrite transmembrane transporter activity
DN405_RS08775	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DN405_RS08795	COG0733	neurotransmitter:sodium symporter activity
DN405_RS08805	COG5566	PFAM Mor transcription activator
DN405_RS08810	COG2323	membrane
DN405_RS08825	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DN405_RS08835	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DN405_RS08840	COG0028	Belongs to the TPP enzyme family
DN405_RS08860	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DN405_RS08885	COG2814	Major facilitator Superfamily
DN405_RS08890	COG3384	dioxygenase
DN405_RS08900	COG3279	Response regulator of the LytR AlgR family
DN405_RS08905	COG0427	acetyl-CoA hydrolase
DN405_RS08925	COG4166	transmembrane transport
DN405_RS08930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DN405_RS08950	COG1914	H( )-stimulated, divalent metal cation uptake system
DN405_RS08965	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DN405_RS08970	COG0531	amino acid
DN405_RS09000	COG2309	aminopeptidase activity
DN405_RS09015	COG0456	acetyltransferase
DN405_RS09035	COG1309	transcriptional regulator
DN405_RS09040	COG2390	Transcriptional regulator
DN405_RS09050	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DN405_RS09055	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
DN405_RS09090	COG4846	Membrane protein involved in cytochrome C biogenesis
DN405_RS09110	COG0583	DNA-binding transcription factor activity
DN405_RS09125	COG0006	proline dipeptidase activity
DN405_RS09135	COG2132	Multicopper oxidase
DN405_RS09160	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DN405_RS09180	COG1114	Component of the transport system for branched-chain amino acids
DN405_RS09190	COG1276	copper resistance
DN405_RS09190	COG2372	response to copper ion
DN405_RS09195	COG4549	nuclear export factor GLE1
DN405_RS09200	COG0697	spore germination
DN405_RS09205	COG0583	DNA-binding transcription factor activity
DN405_RS09210	COG1959	2 iron, 2 sulfur cluster binding
DN405_RS09215	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DN405_RS09220	COG0778	Nitroreductase
DN405_RS09230	COG0628	permease
DN405_RS09240	COG1231	oxidoreductase activity
DN405_RS09250	COG0523	cobalamin synthesis protein
DN405_RS09260	COG0411	ABC transporter
DN405_RS09280	COG0583	DNA-binding transcription factor activity
DN405_RS09290	COG1942	4-Oxalocrotonate Tautomerase
DN405_RS09305	COG1271	oxidase subunit
DN405_RS09310	COG1294	oxidase, subunit
DN405_RS09315	COG4988	ABC transporter
DN405_RS09320	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DN405_RS09330	COG1216	Glycosyl transferase, family 2
DN405_RS09370	COG1686	Belongs to the peptidase S11 family
DN405_RS09385	COG1388	LysM domain
DN405_RS09385	COG0791	NLP P60 protein
DN405_RS09395	COG1132	(ABC) transporter
DN405_RS09400	COG0745	RESPONSE REGULATOR receiver
DN405_RS09405	COG5002	protein histidine kinase activity
DN405_RS09410	COG0300	oxidoreductase activity
DN405_RS09440	COG0460	homoserine dehydrogenase
DN405_RS09465	COG1316	TRANSCRIPTIONal
DN405_RS09475	COG0745	RESPONSE REGULATOR receiver
DN405_RS09480	COG5002	protein histidine kinase activity
DN405_RS09495	COG1285	pathogenesis
DN405_RS09500	COG1247	-acetyltransferase
DN405_RS09520	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DN405_RS09530	COG1082	Xylose isomerase domain protein TIM barrel
DN405_RS09540	COG2814	Major facilitator Superfamily
DN405_RS09545	COG1279	arginine transmembrane transporter activity
DN405_RS09550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DN405_RS09560	COG1752	Esterase of the alpha-beta hydrolase superfamily
DN405_RS09595	COG0577	efflux transmembrane transporter activity
DN405_RS09600	COG2002	toxin-antitoxin pair type II binding
DN405_RS09605	COG1404	Belongs to the peptidase S8 family
DN405_RS09620	COG3152	Membrane
DN405_RS09645	COG0840	transmembrane signaling receptor activity
DN405_RS09660	COG3949	Membrane
DN405_RS09665	COG0783	Belongs to the Dps family
DN405_RS09680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DN405_RS09690	COG1231	oxidoreductase activity
DN405_RS09695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DN405_RS09700	COG4989	oxidoreductase activity
DN405_RS09710	COG0523	cobalamin synthesis protein
DN405_RS09715	COG0456	acetyltransferase
DN405_RS09720	COG0803	Belongs to the bacterial solute-binding protein 9 family
DN405_RS09725	COG0702	epimerase
DN405_RS09735	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DN405_RS09745	COG4166	transmembrane transport
DN405_RS09770	COG5337	Spore coat protein CotH
DN405_RS09775	COG1051	belongs to the nudix hydrolase family
DN405_RS09780	COG0586	Pfam SNARE associated Golgi protein
DN405_RS09785	COG2244	polysaccharide biosynthetic process
DN405_RS09795	COG0701	Predicted permease
DN405_RS09800	COG3689	TIGRFAM TIGR03943 family protein
DN405_RS09805	COG1607	acyl-coa hydrolase
DN405_RS09815	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DN405_RS09830	COG0702	epimerase
DN405_RS09835	COG2839	Protein conserved in bacteria
DN405_RS09840	COG1253	flavin adenine dinucleotide binding
DN405_RS09855	COG1114	Component of the transport system for branched-chain amino acids
DN405_RS09860	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DN405_RS09880	COG0860	N-Acetylmuramoyl-L-alanine amidase
DN405_RS09890	COG1876	peptidase activity
DN405_RS09900	COG0154	amidase activity
DN405_RS09905	COG2211	Major facilitator Superfamily
DN405_RS09920	COG0860	N-Acetylmuramoyl-L-alanine amidase
DN405_RS09930	COG0561	phosphatase activity
DN405_RS09945	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DN405_RS09965	COG1819	glycosyl
DN405_RS09970	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DN405_RS09975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DN405_RS10005	COG0456	acetyltransferase
DN405_RS10040	COG4499	WXG100 protein secretion system (Wss), protein YukC
DN405_RS10095	COG3874	Sporulation protein YtfJ
DN405_RS10120	COG2226	methyltransferase
DN405_RS10140	COG1082	Xylose isomerase domain protein TIM barrel
DN405_RS10145	COG0346	lactoylglutathione lyase activity
DN405_RS10155	COG0604	alcohol dehydrogenase
DN405_RS10160	COG1595	DNA-templated transcription, initiation
DN405_RS10185	COG0386	Belongs to the glutathione peroxidase family
DN405_RS10190	COG1305	Transglutaminase-like
DN405_RS10195	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
DN405_RS10200	COG0714	Associated with various cellular activities
DN405_RS10205	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DN405_RS10210	COG1140	nitrate reductase beta subunit
DN405_RS10215	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
DN405_RS10220	COG2181	nitrate reductase activity
DN405_RS10225	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DN405_RS10230	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DN405_RS10235	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DN405_RS10240	COG0303	'Molybdopterin
DN405_RS10245	COG0314	molybdopterin synthase activity
DN405_RS10255	COG2223	nitrite transmembrane transporter activity
DN405_RS10280	COG1648	precorrin-2 dehydrogenase activity
DN405_RS10290	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DN405_RS10290	COG1587	Uroporphyrinogen-III synthase
DN405_RS10295	COG2146	nitrite reductase [NAD(P)H] activity
DN405_RS10300	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DN405_RS10305	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
DN405_RS10340	COG2359	stage V sporulation protein S
DN405_RS10365	COG0457	Tetratricopeptide repeat
DN405_RS10380	COG1418	mRNA catabolic process
DN405_RS10385	COG0488	(ABC) transporter
DN405_RS10400	COG0629	single-stranded DNA binding
DN405_RS10410	COG1413	lyase activity
DN405_RS10425	COG2521	methyltransferase
DN405_RS10425	COG2136	Putative SAM-dependent methyltransferase
DN405_RS10430	COG0018	arginyl-trna synthetase
DN405_RS10480	COG0017	Asparaginyl-tRNA synthetase
DN405_RS10485	COG0733	neurotransmitter:sodium symporter activity
DN405_RS10510	COG2610	gluconate transmembrane transporter activity
DN405_RS10520	COG1794	racemase activity, acting on amino acids and derivatives
DN405_RS10530	COG0456	acetyltransferase
DN405_RS10540	COG3655	Transcriptional regulator
DN405_RS10545	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DN405_RS10555	COG1131	(ABC) transporter
DN405_RS10560	COG4473	ABC transporter
DN405_RS10570	COG0546	phosphoglycolate phosphatase activity
DN405_RS10585	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DN405_RS10600	COG0768	penicillin binding
DN405_RS10610	COG0204	Acyl-transferase
DN405_RS10615	COG1272	protein, Hemolysin III
DN405_RS10625	COG0805	protein transport
DN405_RS10635	COG1307	EDD domain protein, DegV family
DN405_RS10645	COG1999	signal sequence binding
DN405_RS10650	COG0071	Belongs to the small heat shock protein (HSP20) family
DN405_RS10655	COG0367	asparagine synthase
DN405_RS10670	COG0860	N-Acetylmuramoyl-L-alanine amidase
DN405_RS10675	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DN405_RS10680	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DN405_RS10700	COG1335	isochorismatase
DN405_RS10715	COG0668	transmembrane transport
DN405_RS10720	COG4585	Histidine kinase
DN405_RS10720	COG2203	Gaf domain
DN405_RS10725	COG2197	response regulator
DN405_RS10730	COG1737	Transcriptional regulator
DN405_RS10735	COG0384	phenazine biosynthesis protein PhzF
DN405_RS10740	COG1064	alcohol dehydrogenase
DN405_RS10755	COG1070	Carbohydrate kinase
DN405_RS10765	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
DN405_RS10800	COG1125	glycine betaine transport
DN405_RS10800	COG0517	IMP dehydrogenase activity
DN405_RS10805	COG1174	glycine betaine transport
DN405_RS10840	COG1253	flavin adenine dinucleotide binding
DN405_RS10845	COG1012	belongs to the aldehyde dehydrogenase family
DN405_RS10850	COG5506	Protein of unknown function (DUF1694)
DN405_RS10865	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DN405_RS10870	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DN405_RS10875	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DN405_RS10880	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DN405_RS10885	COG0456	acetyltransferase
DN405_RS10890	COG3829	transcription factor binding
DN405_RS10895	COG1509	lysine 2,3-aminomutase activity
DN405_RS10930	COG4991	sh3 domain protein
DN405_RS10930	COG3064	Membrane
DN405_RS10930	COG0515	serine threonine protein kinase
DN405_RS10940	COG0671	phosphoesterase, PA-phosphatase related
DN405_RS10945	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DN405_RS10950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DN405_RS11030	COG0300	oxidoreductase activity
DN405_RS11050	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DN405_RS11050	COG4499	WXG100 protein secretion system (Wss), protein YukC
DN405_RS11060	COG2814	Major facilitator Superfamily
DN405_RS11065	COG4841	protein insertion into membrane
DN405_RS11070	COG0372	Belongs to the citrate synthase family
DN405_RS11075	COG2079	MmgE PrpD family protein
DN405_RS11080	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DN405_RS11085	COG1960	acyl-CoA dehydrogenase activity
DN405_RS11090	COG2084	Dehydrogenase
DN405_RS11100	COG1280	lysine exporter protein (LysE YggA)
DN405_RS11105	COG1024	Enoyl-CoA hydratase
DN405_RS11120	COG0420	3'-5' exonuclease activity
DN405_RS11125	COG0419	ATPase involved in DNA repair
DN405_RS11150	COG2223	nitrite transmembrane transporter activity
DN405_RS11155	COG1028	Short-chain dehydrogenase reductase Sdr
DN405_RS11160	COG1169	isochorismate synthase
DN405_RS11165	COG1021	2,3-dihydroxybenzoate-AMP ligase
DN405_RS11170	COG3433	isochorismatase activity
DN405_RS11170	COG1535	isochorismatase
DN405_RS11175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DN405_RS11180	COG3251	PFAM MbtH domain protein
DN405_RS11185	COG2814	Major facilitator Superfamily
DN405_RS11200	COG0776	regulation of translation
DN405_RS11210	COG2318	DinB family
DN405_RS11220	COG1115	amino acid carrier protein
DN405_RS11240	COG1187	pseudouridine synthase activity
DN405_RS11245	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DN405_RS11250	COG1136	(ABC) transporter
DN405_RS11260	COG2814	Major facilitator Superfamily
DN405_RS11275	COG0028	Belongs to the TPP enzyme family
DN405_RS11315	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DN405_RS11335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN405_RS11365	COG1247	-acetyltransferase
DN405_RS11385	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DN405_RS11395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DN405_RS11420	COG0561	phosphatase activity
DN405_RS11430	COG0583	DNA-binding transcription factor activity
DN405_RS11435	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DN405_RS11455	COG0583	DNA-binding transcription factor activity
DN405_RS11460	COG2258	MOSC domain
DN405_RS11475	COG1132	(ABC) transporter
DN405_RS11480	COG1132	(ABC) transporter
DN405_RS11505	COG1396	sequence-specific DNA binding
DN405_RS11540	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DN405_RS11545	COG1595	DNA-templated transcription, initiation
DN405_RS11565	COG1649	PFAM Uncharacterised BCR, COG1649
DN405_RS11590	COG2971	BadF BadG BcrA BcrD
DN405_RS11610	COG1846	Transcriptional regulator
DN405_RS11625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN405_RS11700	COG0582	viral genome integration into host DNA
DN405_RS11725	COG4824	toxin secretion phage lysis holin
DN405_RS11730	COG3409	Peptidoglycan-binding domain 1 protein
DN405_RS11730	COG5632	N-Acetylmuramoyl-L-alanine amidase
DN405_RS11730	COG1388	LysM domain
DN405_RS11745	COG3615	Tellurite resistance protein tehB
DN405_RS11745	COG0500	methyltransferase
DN405_RS11760	COG3961	Belongs to the TPP enzyme family
DN405_RS11765	COG1846	Transcriptional regulator
DN405_RS11795	COG2195	Cleaves the N-terminal amino acid of tripeptides
DN405_RS11820	COG2002	toxin-antitoxin pair type II binding
DN405_RS11830	COG0730	response to heat
DN405_RS11835	COG0110	maltose O-acetyltransferase activity
DN405_RS11850	COG2814	Major facilitator Superfamily
DN405_RS11900	COG2312	Erythromycin esterase
DN405_RS11910	COG0741	lytic transglycosylase activity
DN405_RS11915	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DN405_RS11980	COG1760	l-serine dehydratase
DN405_RS11985	COG1760	l-serine dehydratase
DN405_RS11990	COG0814	amino acid
DN405_RS12000	COG0840	transmembrane signaling receptor activity
DN405_RS12035	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DN405_RS12040	COG0768	penicillin binding
DN405_RS12045	COG1595	DNA-templated transcription, initiation
DN405_RS12055	COG0768	penicillin binding
DN405_RS12060	COG0768	penicillin binding
DN405_RS12070	COG1408	metallophosphoesterase
DN405_RS12080	COG1131	(ABC) transporter
DN405_RS12090	COG1309	transcriptional regulator
DN405_RS12105	COG1960	acyl-CoA dehydrogenase activity
DN405_RS12110	COG0439	Biotin carboxylase
DN405_RS12115	COG0511	ligase activity, forming carbon-carbon bonds
DN405_RS12120	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DN405_RS12125	COG1024	Enoyl-CoA hydratase
DN405_RS12130	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DN405_RS12135	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DN405_RS12165	COG0572	uridine kinase
DN405_RS12190	COG1686	Belongs to the peptidase S11 family
DN405_RS12215	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DN405_RS12230	COG3227	Zinc metalloprotease (Elastase)
DN405_RS12235	COG2207	Transcriptional regulator
DN405_RS12265	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DN405_RS12275	COG2814	Major facilitator Superfamily
DN405_RS12280	COG1028	Short-chain dehydrogenase reductase Sdr
DN405_RS12290	COG1733	regulation of RNA biosynthetic process
DN405_RS12295	COG2226	methyltransferase
DN405_RS12335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DN405_RS12345	COG2368	4-hydroxyphenylacetate
DN405_RS12360	COG1063	alcohol dehydrogenase
DN405_RS12370	COG2323	membrane
DN405_RS12385	COG3386	PFAM SMP-30 Gluconolaconase
DN405_RS12400	COG3773	Cell wall hydrolase
DN405_RS12410	COG0745	RESPONSE REGULATOR receiver
DN405_RS12415	COG2205	protein histidine kinase activity
DN405_RS12425	COG0488	(ABC) transporter
DN405_RS12435	COG1136	(ABC) transporter
DN405_RS12440	COG0577	efflux transmembrane transporter activity
DN405_RS12460	COG0460	homoserine dehydrogenase
DN405_RS12465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DN405_RS12475	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DN405_RS12505	COG0582	viral genome integration into host DNA
DN405_RS12615	COG0582	viral genome integration into host DNA
DN405_RS12675	COG0740	serine-type endopeptidase activity
DN405_RS12755	COG4824	toxin secretion phage lysis holin
DN405_RS12810	COG2124	cytochrome p450
DN405_RS12850	COG0561	phosphatase activity
DN405_RS12855	COG5002	protein histidine kinase activity
DN405_RS12860	COG0768	penicillin binding
DN405_RS12870	COG1819	glycosyl
DN405_RS12875	COG1794	racemase activity, acting on amino acids and derivatives
DN405_RS12900	COG2205	protein histidine kinase activity
DN405_RS13015	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DN405_RS13025	COG0745	RESPONSE REGULATOR receiver
DN405_RS13030	COG5002	protein histidine kinase activity
DN405_RS13035	COG0604	alcohol dehydrogenase
DN405_RS13040	COG0671	phosphoesterase, PA-phosphatase related
DN405_RS13045	COG0768	penicillin binding
DN405_RS13085	COG0693	protein deglycase activity
DN405_RS13100	COG0584	glycerophosphoryl diester phosphodiesterase
DN405_RS13120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DN405_RS13125	COG0697	spore germination
DN405_RS13160	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DN405_RS13165	COG2223	nitrite transmembrane transporter activity
DN405_RS13180	COG0592	DNA-directed DNA polymerase activity
DN405_RS13200	COG3878	Protein conserved in bacteria
DN405_RS13210	COG3693	PFAM glycoside hydrolase, family 10
DN405_RS13210	COG3507	Belongs to the glycosyl hydrolase 43 family
DN405_RS13210	COG2382	esterase
DN405_RS13225	COG4667	esterase of the alpha-beta hydrolase superfamily
DN405_RS13265	COG0322	excinuclease ABC activity
DN405_RS13305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DN405_RS13340	COG1011	Hydrolase
DN405_RS13345	COG0745	RESPONSE REGULATOR receiver
DN405_RS13350	COG5002	protein histidine kinase activity
DN405_RS13365	COG1136	(ABC) transporter
DN405_RS13370	COG0577	efflux transmembrane transporter activity
DN405_RS13375	COG1073	alpha beta
DN405_RS13380	COG0657	acetylesterase activity
DN405_RS13385	COG0076	glutamate decarboxylase activity
DN405_RS13400	COG1523	belongs to the glycosyl hydrolase 13 family
DN405_RS13405	COG3227	Zinc metalloprotease (Elastase)
DN405_RS13410	COG0737	Belongs to the 5'-nucleotidase family
DN405_RS13430	COG0201	protein transport
DN405_RS13435	COG0697	spore germination
DN405_RS13440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DN405_RS13445	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DN405_RS13475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DN405_RS13490	COG2959	enzyme of heme biosynthesis
DN405_RS13535	COG1309	transcriptional regulator
DN405_RS13560	COG3284	Transcriptional regulator
DN405_RS13575	COG1349	DNA-binding transcription factor activity
DN405_RS13590	COG1959	2 iron, 2 sulfur cluster binding
DN405_RS13605	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DN405_RS13610	COG0508	dehydrogenase complex catalyzes the overall conversion of
DN405_RS13615	COG0022	dehydrogenase e1 component
DN405_RS13620	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DN405_RS13630	COG1028	Short-chain dehydrogenase reductase Sdr
DN405_RS13660	COG4176	ABC-type proline glycine betaine transport system permease component
DN405_RS13665	COG0517	IMP dehydrogenase activity
DN405_RS13665	COG4175	Glycine betaine
DN405_RS13695	COG2153	protein acetylation
DN405_RS13700	COG3397	chitin binding
DN405_RS13705	COG1819	glycosyl
DN405_RS13725	COG2205	protein histidine kinase activity
DN405_RS13730	COG2226	methyltransferase
DN405_RS13735	COG2315	Protein conserved in bacteria
DN405_RS13780	COG0456	acetyltransferase
DN405_RS13785	COG3973	AAA domain
DN405_RS13800	COG0514	ATP-dependent DNA helicase (RecQ)
DN405_RS13835	COG4637	Psort location Cytoplasmic, score
DN405_RS13855	COG3397	chitin binding
DN405_RS13870	COG1162	GTPase activity
DN405_RS13875	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DN405_RS13880	COG1115	amino acid carrier protein
DN405_RS13885	COG1012	belongs to the aldehyde dehydrogenase family
DN405_RS13890	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DN405_RS13900	COG3938	Belongs to the proline racemase family
DN405_RS13905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DN405_RS13945	COG0586	Pfam SNARE associated Golgi protein
DN405_RS13955	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DN405_RS13965	COG4166	transmembrane transport
DN405_RS13975	COG4948	Mandelate Racemase Muconate Lactonizing
DN405_RS13990	COG0667	Aldo Keto reductase
DN405_RS14035	COG3850	Histidine kinase
DN405_RS14035	COG5002	protein histidine kinase activity
DN405_RS14040	COG0745	RESPONSE REGULATOR receiver
DN405_RS14075	COG1164	Oligoendopeptidase f
DN405_RS14080	COG1307	EDD domain protein, DegV family
DN405_RS14120	COG2814	Major facilitator Superfamily
DN405_RS14130	COG1664	Polymer-forming cytoskeletal
DN405_RS14135	COG0789	Transcriptional regulator
DN405_RS14140	COG4533	DNA binding
DN405_RS14145	COG2814	Major facilitator Superfamily
DN405_RS14145	COG0477	Major facilitator Superfamily
DN405_RS14165	COG2261	transglycosylase associated protein
DN405_RS14180	COG2226	methyltransferase
DN405_RS14215	COG0436	Aminotransferase
DN405_RS14220	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DN405_RS14230	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
DN405_RS14270	COG0628	permease
DN405_RS14280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DN405_RS14285	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DN405_RS14290	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DN405_RS14330	COG2746	aminoglycoside 3-N-acetyltransferase activity
DN405_RS14350	COG0697	spore germination
DN405_RS14380	COG4912	Dna alkylation repair
DN405_RS14385	COG0346	lactoylglutathione lyase activity
DN405_RS14405	COG0861	Integral membrane protein TerC family
DN405_RS14410	COG1368	sulfuric ester hydrolase activity
DN405_RS14415	COG0488	(ABC) transporter
DN405_RS14420	COG2409	Drug exporters of the RND superfamily
DN405_RS14420	COG1033	growth of symbiont in host cell
DN405_RS14425	COG1309	transcriptional regulator
DN405_RS14440	COG0287	Prephenate dehydrogenase
DN405_RS14455	COG1605	Chorismate mutase
DN405_RS14455	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DN405_RS14505	COG3584	3D domain protein
DN405_RS14505	COG1388	LysM domain
DN405_RS14515	COG0346	lactoylglutathione lyase activity
DN405_RS14520	COG0277	FAD linked oxidase domain protein
DN405_RS14545	COG1879	ABC-type sugar transport system periplasmic component
DN405_RS14550	COG1172	Belongs to the binding-protein-dependent transport system permease family
DN405_RS14555	COG1172	Belongs to the binding-protein-dependent transport system permease family
DN405_RS14565	COG2390	Transcriptional regulator
DN405_RS14570	COG1070	Carbohydrate kinase
DN405_RS14590	COG2329	Antibiotic biosynthesis monooxygenase
DN405_RS14610	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DN405_RS14625	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DN405_RS14630	COG4187	Peptidase family M20/M25/M40
DN405_RS14635	COG1414	Transcriptional regulator
DN405_RS14645	COG0833	amino acid
DN405_RS14655	COG3239	Fatty acid desaturase
DN405_RS14665	COG2720	vancomycin resistance protein
DN405_RS14670	COG1785	Belongs to the alkaline phosphatase family
DN405_RS14680	COG3655	Transcriptional regulator
DN405_RS14695	COG4377	Putative membrane peptidase family (DUF2324)
DN405_RS14705	COG3279	Response regulator of the LytR AlgR family
DN405_RS14715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DN405_RS14720	COG0346	lactoylglutathione lyase activity
DN405_RS14750	COG0714	Associated with various cellular activities
DN405_RS14775	COG0463	Glycosyl transferase, family 2
DN405_RS14805	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DN405_RS14810	COG0753	catalase activity
DN405_RS14850	COG0714	Associated with various cellular activities
DN405_RS14895	COG0778	Nitroreductase
DN405_RS14900	COG1846	Transcriptional regulator
DN405_RS14925	COG3831	ATPase activity
DN405_RS14925	COG4884	unkown
DN405_RS14950	COG0456	acetyltransferase
DN405_RS14965	COG0697	spore germination
DN405_RS14970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DN405_RS15010	COG0730	response to heat
DN405_RS15020	COG0833	amino acid
DN405_RS15030	COG4335	DNA alkylation repair
DN405_RS15090	COG0768	penicillin binding
DN405_RS15120	COG1984	allophanate hydrolase subunit 2
DN405_RS15125	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DN405_RS15130	COG1414	Transcriptional regulator
DN405_RS15145	COG0640	Transcriptional regulator
DN405_RS15155	COG1960	acyl-CoA dehydrogenase activity
DN405_RS15170	COG3314	Sporulation integral membrane protein YlbJ
DN405_RS15190	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
DN405_RS15215	COG0574	Belongs to the PEP-utilizing enzyme family
DN405_RS15215	COG3848	Pyruvate phosphate dikinase
DN405_RS15220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN405_RS15240	COG1063	alcohol dehydrogenase
DN405_RS15245	COG1027	Aspartate ammonia-lyase
DN405_RS15250	COG0252	asparaginase activity
DN405_RS15255	COG1396	sequence-specific DNA binding
DN405_RS15290	COG5002	protein histidine kinase activity
DN405_RS15315	COG2207	Transcriptional regulator
DN405_RS15335	COG0322	excinuclease ABC activity
DN405_RS15340	COG0531	amino acid
DN405_RS15345	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DN405_RS15355	COG0531	amino acid
DN405_RS15360	COG0697	spore germination
DN405_RS15365	COG0784	Response regulator, receiver
DN405_RS15370	COG4191	Histidine kinase
DN405_RS15375	COG2066	Belongs to the glutaminase family
DN405_RS15380	COG1115	amino acid carrier protein
DN405_RS15410	COG0737	Belongs to the 5'-nucleotidase family
DN405_RS15415	COG2267	carboxylic ester hydrolase activity
DN405_RS15420	COG1335	isochorismatase
DN405_RS15440	COG0583	DNA-binding transcription factor activity
DN405_RS15445	COG1846	Transcriptional regulator
DN405_RS15450	COG0598	Magnesium transport protein CorA
DN405_RS15470	COG1073	alpha beta
DN405_RS15490	COG0415	Belongs to the DNA photolyase family
DN405_RS15505	COG0288	reversible hydration of carbon dioxide
DN405_RS15515	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DN405_RS15520	COG5609	conserved protein (DUF2294)
DN405_RS15535	COG0456	acetyltransferase
DN405_RS15540	COG1575	Belongs to the MenA family. Type 1 subfamily
DN405_RS15555	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DN405_RS15565	COG2814	Major facilitator Superfamily
DN405_RS15580	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DN405_RS15580	COG3320	Male sterility
DN405_RS15585	COG1309	transcriptional regulator
DN405_RS15590	COG2814	Major facilitator Superfamily
DN405_RS15595	COG1309	transcriptional regulator
DN405_RS15600	COG1028	Short-chain dehydrogenase reductase Sdr
DN405_RS15605	COG1522	sequence-specific DNA binding
DN405_RS15620	COG0346	lactoylglutathione lyase activity
DN405_RS15675	COG2814	Major facilitator Superfamily
DN405_RS15690	COG2515	1-aminocyclopropane-1-carboxylate deaminase
DN405_RS15700	COG1690	Belongs to the RtcB family
DN405_RS15710	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DN405_RS15730	COG0577	efflux transmembrane transporter activity
DN405_RS15750	COG5002	protein histidine kinase activity
DN405_RS15750	COG3850	Histidine kinase
DN405_RS15760	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DN405_RS15770	COG1619	proteins homologs of microcin C7 resistance protein MccF
DN405_RS15795	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DN405_RS15840	COG3409	Peptidoglycan-binding domain 1 protein
DN405_RS15840	COG5632	N-Acetylmuramoyl-L-alanine amidase
DN405_RS15945	COG1876	peptidase activity
DN405_RS15950	COG2843	Capsule synthesis protein
DN405_RS15960	COG0477	Major facilitator Superfamily
DN405_RS15975	COG1846	Transcriptional regulator
DN405_RS15980	COG2814	Major facilitator Superfamily
DN405_RS15990	COG2031	fatty acid transporter
DN405_RS16000	COG2249	NAD(P)H dehydrogenase (quinone) activity
DN405_RS16055	COG1288	antiporter activity
DN405_RS16060	COG2356	endonuclease I
DN405_RS16085	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DN405_RS16105	COG1733	regulation of RNA biosynthetic process
DN405_RS16110	COG0778	Nitroreductase
DN405_RS16120	COG0469	pyruvate kinase activity
DN405_RS16140	COG1028	Short-chain dehydrogenase reductase Sdr
DN405_RS16150	COG1131	(ABC) transporter
DN405_RS16180	COG1011	Hydrolase
DN405_RS16190	COG2365	Tyrosine phosphatase family
DN405_RS16225	COG0628	permease
DN405_RS16250	COG0500	methyltransferase
DN405_RS16290	COG1253	flavin adenine dinucleotide binding
DN405_RS16295	COG0789	Transcriptional regulator
DN405_RS16305	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DN405_RS16335	COG0697	spore germination
DN405_RS16345	COG1357	PFAM Pentapeptide repeats (8 copies)
DN405_RS16350	COG3813	Protein conserved in bacteria
DN405_RS16355	COG2706	6-phosphogluconolactonase activity
DN405_RS16360	COG1070	Carbohydrate kinase
DN405_RS16370	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DN405_RS16375	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
DN405_RS16385	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DN405_RS16390	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DN405_RS16400	COG0604	alcohol dehydrogenase
DN405_RS16405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DN405_RS16410	COG0789	Transcriptional regulator
DN405_RS16415	COG4221	oxidoreductase activity
DN405_RS16425	COG1028	Short-chain dehydrogenase reductase Sdr
DN405_RS16440	COG0840	transmembrane signaling receptor activity
DN405_RS16450	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DN405_RS16450	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DN405_RS16455	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DN405_RS16455	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DN405_RS16460	COG1733	regulation of RNA biosynthetic process
DN405_RS16475	COG0656	L-ascorbic acid biosynthetic process
DN405_RS16480	COG2814	Major facilitator Superfamily
DN405_RS16505	COG2824	Alkylphosphonate utilization operon protein PhnA
DN405_RS16510	COG0659	secondary active sulfate transmembrane transporter activity
DN405_RS16525	COG0814	amino acid
DN405_RS16560	COG1733	regulation of RNA biosynthetic process
DN405_RS16565	COG2188	Transcriptional regulator
DN405_RS16570	COG0673	inositol 2-dehydrogenase activity
DN405_RS16575	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DN405_RS16580	COG1733	regulation of RNA biosynthetic process
DN405_RS16585	COG1733	regulation of RNA biosynthetic process
DN405_RS16610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN405_RS16630	COG0384	phenazine biosynthesis protein PhzF
DN405_RS16635	COG0318	PFAM AMP-dependent synthetase and ligase
DN405_RS16640	COG2249	NAD(P)H dehydrogenase (quinone) activity
DN405_RS16645	COG1733	regulation of RNA biosynthetic process
DN405_RS16665	COG1191	sigma factor activity
DN405_RS16680	COG3226	Transcriptional regulator
DN405_RS16685	COG0076	glutamate decarboxylase activity
DN405_RS16710	COG1280	lysine exporter protein (LysE YggA)
DN405_RS16755	COG1151	hydroxylamine reductase activity
DN405_RS16785	COG2072	flavoprotein involved in K transport
DN405_RS16825	COG1113	amino acid transport
DN405_RS16830	COG2814	Major facilitator Superfamily
DN405_RS16870	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DN405_RS16875	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DN405_RS16885	COG1247	-acetyltransferase
DN405_RS16890	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DN405_RS16895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DN405_RS16900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DN405_RS16905	COG3739	integral membrane protein
DN405_RS16925	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DN405_RS16940	COG0583	DNA-binding transcription factor activity
DN405_RS16960	COG1193	negative regulation of DNA recombination
DN405_RS16970	COG2162	N-hydroxyarylamine O-acetyltransferase activity
DN405_RS16975	COG1164	Oligoendopeptidase f
DN405_RS17000	COG3781	membrane
DN405_RS17020	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DN405_RS17045	COG0584	glycerophosphoryl diester phosphodiesterase
DN405_RS17055	COG0640	Transcriptional regulator
DN405_RS17060	COG0604	alcohol dehydrogenase
DN405_RS17070	COG0457	Tetratricopeptide repeat
DN405_RS17085	COG0277	FAD linked oxidase domain protein
DN405_RS17110	COG1183	phosphatidylcholine synthase activity
DN405_RS17120	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DN405_RS17120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN405_RS17125	COG1252	NADH dehydrogenase
DN405_RS17135	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DN405_RS17145	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DN405_RS17160	COG0457	Tetratricopeptide repeat
DN405_RS17190	COG1309	transcriptional regulator
DN405_RS17225	COG3852	Histidine kinase
DN405_RS17235	COG1285	pathogenesis
DN405_RS17245	COG2514	catechol 2,3-dioxygenase activity
DN405_RS17250	COG2720	vancomycin resistance protein
DN405_RS17285	COG0716	FMN binding
DN405_RS17295	COG0494	nUDIX hydrolase
DN405_RS17315	COG1028	Short-chain dehydrogenase reductase Sdr
DN405_RS17325	COG0165	Argininosuccinate lyase
DN405_RS17340	COG4145	pantothenate transmembrane transporter activity
DN405_RS17350	COG1012	belongs to the aldehyde dehydrogenase family
DN405_RS17355	COG1028	Short-chain dehydrogenase reductase Sdr
DN405_RS17365	COG1657	PFAM Prenyltransferase squalene oxidase
DN405_RS17370	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
DN405_RS17375	COG2962	Rard protein
DN405_RS17380	COG3326	Membrane
DN405_RS17395	COG0489	protein tyrosine kinase activity
DN405_RS17405	COG0314	molybdopterin synthase activity
DN405_RS17410	COG0303	'Molybdopterin
DN405_RS17415	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DN405_RS17420	COG2116	formate transmembrane transporter activity
DN405_RS17430	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DN405_RS17435	COG5609	conserved protein (DUF2294)
DN405_RS17440	COG2427	Protein of unknown function (DUF1641)
DN405_RS17445	COG3383	formate dehydrogenase (NAD+) activity
DN405_RS17450	COG0697	spore germination
DN405_RS17465	COG0531	amino acid
DN405_RS17500	COG2226	methyltransferase
DN405_RS17505	COG4166	transmembrane transport
DN405_RS17510	COG4166	transmembrane transport
DN405_RS17515	COG4166	transmembrane transport
DN405_RS17520	COG1301	dicarboxylic acid transport
DN405_RS17525	COG1316	TRANSCRIPTIONal
DN405_RS17535	COG1595	DNA-templated transcription, initiation
DN405_RS17545	COG1131	(ABC) transporter
DN405_RS17555	COG0673	inositol 2-dehydrogenase activity
DN405_RS17560	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DN405_RS17565	COG0187	DNA topoisomerase II activity
DN405_RS17570	COG1832	CoA-binding protein
DN405_RS17575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DN405_RS17580	COG0745	RESPONSE REGULATOR receiver
DN405_RS17600	COG4841	protein insertion into membrane
DN405_RS17605	COG0824	Thioesterase
DN405_RS17635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DN405_RS17645	COG2274	protein secretion by the type I secretion system
DN405_RS17650	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DN405_RS17680	COG2211	Major facilitator Superfamily
DN405_RS17690	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DN405_RS17705	COG0183	Belongs to the thiolase family
DN405_RS17710	COG0318	PFAM AMP-dependent synthetase and ligase
DN405_RS17715	COG1268	BioY protein
DN405_RS17720	COG0318	PFAM AMP-dependent synthetase and ligase
DN405_RS17750	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
DN405_RS17770	COG0830	nickel cation binding
DN405_RS17810	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DN405_RS17825	COG5002	protein histidine kinase activity
DN405_RS17830	COG0400	carboxylic ester hydrolase activity
DN405_RS17835	COG0346	lactoylglutathione lyase activity
DN405_RS17840	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DN405_RS17850	COG0069	glutamate synthase activity
DN405_RS17855	COG1902	pentaerythritol trinitrate reductase activity
DN405_RS17860	COG1329	Transcriptional regulator
DN405_RS17865	COG0010	Belongs to the arginase family
DN405_RS17920	COG4846	Membrane protein involved in cytochrome C biogenesis
DN405_RS17925	COG0785	Cytochrome C biogenesis protein
DN405_RS17940	COG1473	amidohydrolase
DN405_RS17950	COG1131	(ABC) transporter
DN405_RS17965	COG0583	DNA-binding transcription factor activity
DN405_RS17975	COG1346	cytolysis
DN405_RS17990	COG0730	response to heat
DN405_RS18015	COG1132	(ABC) transporter
DN405_RS18020	COG1132	(ABC) transporter
DN405_RS18045	COG3639	organic phosphonate transmembrane transporter activity
DN405_RS18055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DN405_RS18060	COG0737	Belongs to the 5'-nucleotidase family
DN405_RS18070	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DN405_RS18090	COG1695	Transcriptional regulator
DN405_RS18100	COG1388	LysM domain
DN405_RS18100	COG3409	Peptidoglycan-binding domain 1 protein
DN405_RS18100	COG5632	N-Acetylmuramoyl-L-alanine amidase
DN405_RS18105	COG0739	heme binding
DN405_RS18110	COG0741	lytic transglycosylase activity
DN405_RS18140	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DN405_RS18145	COG0174	glutamine synthetase
DN405_RS18150	COG0789	Transcriptional regulator
DN405_RS18155	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
DN405_RS18160	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DN405_RS18165	COG2860	membrane
DN405_RS18170	COG0464	growth
DN405_RS18200	COG3584	3D domain protein
DN405_RS18200	COG1388	LysM domain
DN405_RS18205	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DN405_RS18205	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DN405_RS18205	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DN405_RS18210	COG1105	Belongs to the carbohydrate kinase PfkB family
DN405_RS18215	COG1349	DNA-binding transcription factor activity
DN405_RS18220	COG1979	alcohol dehydrogenase
DN405_RS18225	COG2322	membrane
DN405_RS18235	COG1113	amino acid transport
DN405_RS18250	COG1408	metallophosphoesterase
DN405_RS18255	COG2116	formate transmembrane transporter activity
DN405_RS18270	COG2217	Heavy metal translocating P-type atpase
DN405_RS18275	COG2608	mercury ion transmembrane transporter activity
DN405_RS18280	COG1937	Protein conserved in bacteria
DN405_RS18290	COG2819	hydrolase of the alpha beta superfamily
DN405_RS18295	COG1120	ATPase activity
DN405_RS18300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DN405_RS18305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DN405_RS18310	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DN405_RS18320	COG2169	Transcriptional regulator
DN405_RS18325	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DN405_RS18330	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DN405_RS18340	COG2364	Membrane
DN405_RS18355	COG2267	carboxylic ester hydrolase activity
DN405_RS18360	COG5001	Diguanylate cyclase
DN405_RS18360	COG3300	MHYT domain
DN405_RS18400	COG1346	cytolysis
DN405_RS18410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DN405_RS18420	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DN405_RS18435	COG1404	Belongs to the peptidase S8 family
DN405_RS18440	COG3773	Cell wall hydrolase
DN405_RS18455	COG1368	sulfuric ester hydrolase activity
DN405_RS18460	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DN405_RS18485	COG4550	Control of competence regulator ComK, YlbF/YmcA
DN405_RS18495	COG1013	pyruvate-flavodoxin oxidoreductase activity
DN405_RS18500	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DN405_RS18500	COG0674	pyruvate-flavodoxin oxidoreductase activity
DN405_RS18510	COG2359	stage V sporulation protein S
DN405_RS18515	COG1692	metallophosphoesterase
DN405_RS18535	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DN405_RS18540	COG1426	Protein conserved in bacteria
DN405_RS18555	COG0300	oxidoreductase activity
DN405_RS18560	COG0612	Peptidase, M16
DN405_RS18565	COG0612	Peptidase, M16
DN405_RS18570	COG1079	Belongs to the binding-protein-dependent transport system permease family
DN405_RS18575	COG4603	Belongs to the binding-protein-dependent transport system permease family
DN405_RS18580	COG3845	ABC transporter
DN405_RS18585	COG1744	ABC transporter substrate-binding protein PnrA-like
DN405_RS18590	COG2188	Transcriptional regulator
DN405_RS18610	COG0740	serine-type endopeptidase activity
DN405_RS18615	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DN405_RS18625	COG0527	aspartate kinase activity
DN405_RS18630	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DN405_RS18635	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DN405_RS18640	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DN405_RS18645	COG1873	PFAM PRC-barrel domain
DN405_RS18650	COG0612	Peptidase, M16
DN405_RS18655	COG0726	polysaccharide deacetylase
DN405_RS18670	COG0196	riboflavin kinase activity
DN405_RS18680	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DN405_RS18685	COG1550	Protein conserved in bacteria
DN405_RS18695	COG1358	cellular component organization or biogenesis
DN405_RS18700	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DN405_RS18705	COG0195	Participates in both transcription termination and antitermination
DN405_RS18725	COG0750	zinc metalloprotease
DN405_RS18735	COG4589	Belongs to the CDS family
DN405_RS18780	COG4974	Belongs to the 'phage' integrase family
DN405_RS18790	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DN405_RS18795	COG0758	DNA mediated transformation
DN405_RS18800	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DN405_RS18840	COG1837	Belongs to the UPF0109 family
DN405_RS18850	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DN405_RS18860	COG0552	protein localization to endoplasmic reticulum
DN405_RS18865	COG1196	nuclear chromosome segregation
DN405_RS18875	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DN405_RS18880	COG1028	Short-chain dehydrogenase reductase Sdr
DN405_RS18885	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DN405_RS18900	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DN405_RS18905	COG1461	Dihydroxyacetone kinase
DN405_RS18910	COG1302	Protein conserved in bacteria
DN405_RS18925	COG1564	THIamine pyrophosphokinase
DN405_RS18930	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DN405_RS18940	COG2815	serine threonine protein kinase
DN405_RS18940	COG0515	serine threonine protein kinase
DN405_RS18945	COG0631	protein serine/threonine phosphatase activity
DN405_RS18955	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DN405_RS18955	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DN405_RS18970	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DN405_RS18975	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DN405_RS18995	COG1561	YicC-like family, N-terminal region
DN405_RS19000	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DN405_RS19010	COG0006	proline dipeptidase activity
DN405_RS19025	COG3069	C4-dicarboxylate transmembrane transporter activity
DN405_RS19085	COG0564	pseudouridine synthase activity
DN405_RS19105	COG3599	regulation of cell shape
DN405_RS19110	COG2302	S4 RNA-binding domain
DN405_RS19115	COG0762	integral membrane protein
DN405_RS19125	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DN405_RS19135	COG1873	PFAM PRC-barrel domain
DN405_RS19140	COG1191	sigma factor activity
DN405_RS19145	COG1191	sigma factor activity
DN405_RS19155	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DN405_RS19160	COG0849	cell division
DN405_RS19180	COG0772	Belongs to the SEDS family
DN405_RS19200	COG0768	penicillin binding
DN405_RS19205	COG0768	penicillin binding
DN405_RS19225	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DN405_RS19240	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DN405_RS19245	COG1399	metal-binding, possibly nucleic acid-binding protein
DN405_RS19255	COG3480	Lon protease (S16) C-terminal proteolytic domain
DN405_RS19260	COG1752	Esterase of the alpha-beta hydrolase superfamily
DN405_RS19265	COG3314	Sporulation integral membrane protein YlbJ
DN405_RS19275	COG0742	ribosomal rna small subunit methyltransferase
DN405_RS19290	COG3679	Belongs to the UPF0342 family
DN405_RS19295	COG0406	alpha-ribazole phosphatase activity
DN405_RS19310	COG2340	Cysteine-rich secretory protein family
DN405_RS19325	COG3336	cytochrome c oxidase
DN405_RS19360	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DN405_RS19370	COG0772	Belongs to the SEDS family
DN405_RS19380	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DN405_RS19385	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DN405_RS19395	COG4896	Protein conserved in bacteria
DN405_RS19410	COG1217	gtp-binding protein TYPA
DN405_RS19420	COG0483	inositol monophosphate 1-phosphatase activity
DN405_RS19440	COG1982	Orn Lys Arg decarboxylase major
DN405_RS19490	COG0022	dehydrogenase e1 component
DN405_RS19495	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DN405_RS19510	COG0561	phosphatase activity
DN405_RS19525	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DN405_RS19530	COG0569	domain protein
DN405_RS19550	COG0583	DNA-binding transcription factor activity
DN405_RS19555	COG0517	IMP dehydrogenase activity
DN405_RS19565	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
DN405_RS19570	COG4703	Protein of unknown function (DUF1797)
DN405_RS19585	COG2200	EAL domain
DN405_RS19590	COG1028	Short-chain dehydrogenase reductase Sdr
DN405_RS19595	COG1408	metallophosphoesterase
DN405_RS19640	COG2814	Major facilitator Superfamily
DN405_RS19660	COG3209	COG3209 Rhs family protein
DN405_RS19670	COG2205	protein histidine kinase activity
DN405_RS19680	COG0436	Aminotransferase
DN405_RS19685	COG1609	Transcriptional regulator
DN405_RS19690	COG3833	ABC-type maltose transport systems, permease component
DN405_RS19695	COG1175	transmembrane transport
DN405_RS19700	COG2182	Extracellular solute-binding protein
DN405_RS19710	COG0366	Alpha amylase catalytic
DN405_RS19715	COG3842	ATPase activity
DN405_RS19755	COG0183	Belongs to the thiolase family
DN405_RS19790	COG1695	Transcriptional regulator
DN405_RS19795	COG1028	Short-chain dehydrogenase reductase Sdr
DN405_RS19815	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DN405_RS19820	COG0436	Aminotransferase
DN405_RS19855	COG2084	Dehydrogenase
DN405_RS19865	COG2199	diguanylate cyclase activity
DN405_RS19870	COG0778	Nitroreductase
DN405_RS19895	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DN405_RS19895	COG2190	(PTS) system
DN405_RS19895	COG1263	PTS System
DN405_RS19900	COG3711	transcriptional antiterminator
DN405_RS19910	COG2188	Transcriptional regulator
DN405_RS19920	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DN405_RS19950	COG1547	Domain of unknown function (DUF309)
DN405_RS19955	COG0456	acetyltransferase
DN405_RS19960	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DN405_RS19965	COG4086	secreted protein
DN405_RS19970	COG0561	phosphatase activity
DN405_RS19975	COG0697	spore germination
DN405_RS19990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DN405_RS20015	COG0733	neurotransmitter:sodium symporter activity
DN405_RS20035	COG1686	Belongs to the peptidase S11 family
DN405_RS20045	COG1725	Transcriptional regulator
DN405_RS20050	COG1131	(ABC) transporter
DN405_RS20070	COG1846	Transcriptional regulator
DN405_RS20085	COG0598	Magnesium transport protein CorA
DN405_RS20110	COG4974	Belongs to the 'phage' integrase family
DN405_RS20120	COG0735	belongs to the Fur family
DN405_RS20125	COG1300	Membrane
DN405_RS20145	COG0667	Aldo Keto reductase
DN405_RS20150	COG0656	L-ascorbic acid biosynthetic process
DN405_RS20155	COG0456	acetyltransferase
DN405_RS20155	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DN405_RS20165	COG0737	Belongs to the 5'-nucleotidase family
DN405_RS20165	COG1525	nuclease
DN405_RS20165	COG4085	toxin activity
DN405_RS20175	COG0596	Alpha beta hydrolase
DN405_RS20180	COG2056	Na+-H+ antiporter family
DN405_RS20185	COG1609	Transcriptional regulator
DN405_RS20190	COG0456	acetyltransferase
DN405_RS20195	COG1073	alpha beta
DN405_RS20210	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DN405_RS20210	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DN405_RS20215	COG0307	riboflavin synthase, alpha
DN405_RS20245	COG1073	alpha beta
DN405_RS20245	COG2226	methyltransferase
DN405_RS20260	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DN405_RS20270	COG1757	Na H antiporter
DN405_RS20275	COG0737	Belongs to the 5'-nucleotidase family
DN405_RS20285	COG1522	sequence-specific DNA binding
DN405_RS20330	COG0300	oxidoreductase activity
DN405_RS20335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN405_RS20340	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DN405_RS20345	COG1760	l-serine dehydratase
DN405_RS20350	COG1760	l-serine dehydratase
DN405_RS20390	COG2195	Cleaves the N-terminal amino acid of tripeptides
DN405_RS20395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DN405_RS20410	COG1376	ErfK ybiS ycfS ynhG family protein
DN405_RS20415	COG4129	membrane
DN405_RS20420	COG1126	abc transporter atp-binding protein
DN405_RS20425	COG0765	amino acid transport
DN405_RS20430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DN405_RS20450	COG2323	membrane
DN405_RS20455	COG0772	Belongs to the SEDS family
DN405_RS20460	COG0508	dehydrogenase complex catalyzes the overall conversion of
DN405_RS20465	COG0022	dehydrogenase e1 component
DN405_RS20470	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DN405_RS20475	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DN405_RS20490	COG0280	phosphate acetyltransferase
DN405_RS20500	COG3829	transcription factor binding
DN405_RS20500	COG3290	protein histidine kinase activity
DN405_RS20510	COG0584	glycerophosphoryl diester phosphodiesterase
DN405_RS20515	COG3093	addiction module antidote protein HigA
DN405_RS20535	COG0750	zinc metalloprotease
DN405_RS20540	COG0497	DNA recombination
DN405_RS20550	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DN405_RS20560	COG0142	geranyltranstransferase activity
DN405_RS20585	COG1302	Protein conserved in bacteria
DN405_RS20590	COG0439	Biotin carboxylase
DN405_RS20595	COG0511	ligase activity, forming carbon-carbon bonds
DN405_RS20640	COG3854	ATPases associated with a variety of cellular activities
DN405_RS20665	COG0006	proline dipeptidase activity
DN405_RS20680	COG3872	metal-dependent enzyme
DN405_RS20690	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DN405_RS20705	COG1695	Transcriptional regulator
DN405_RS20725	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DN405_RS20735	COG1609	Transcriptional regulator
DN405_RS20745	COG2076	Multidrug Resistance protein
DN405_RS20750	COG2076	Multidrug Resistance protein
DN405_RS20780	COG1131	(ABC) transporter
DN405_RS20785	COG1725	Transcriptional regulator
DN405_RS20820	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DN405_RS20870	COG1204	response to ionizing radiation
DN405_RS20970	COG1410	methionine synthase
DN405_RS20970	COG0646	methionine synthase
DN405_RS20975	COG0646	methionine synthase
DN405_RS20975	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DN405_RS20980	COG0626	cystathionine gamma-synthase activity
DN405_RS20985	COG0626	cystathionine gamma-synthase activity
DN405_RS21005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN405_RS21015	COG1940	carbohydrate kinase activity
DN405_RS21020	COG4483	Protein conserved in bacteria
DN405_RS21025	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DN405_RS21030	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DN405_RS21035	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DN405_RS21040	COG0704	Plays a role in the regulation of phosphate uptake
DN405_RS21050	COG0573	inorganic phosphate transmembrane transporter activity
DN405_RS21055	COG0573	inorganic phosphate transmembrane transporter activity
DN405_RS21060	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DN405_RS21065	COG0768	penicillin binding
DN405_RS21070	COG0477	Major facilitator Superfamily
DN405_RS21075	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DN405_RS21085	COG5521	maltodextrose utilization protein MalA
DN405_RS21100	COG0735	belongs to the Fur family
DN405_RS21105	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DN405_RS21110	COG1121	(ABC) transporter
DN405_RS21115	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DN405_RS21145	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DN405_RS21150	COG2384	SAM-dependent methyltransferase
DN405_RS21160	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DN405_RS21165	COG0358	DNA primase activity
DN405_RS21175	COG0517	IMP dehydrogenase activity
DN405_RS21190	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DN405_RS21195	COG0295	cytidine deaminase activity
DN405_RS21200	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DN405_RS21210	COG1480	7TM receptor with intracellular HD hydrolase
DN405_RS21215	COG1702	phosphate starvation-inducible protein PhoH
DN405_RS21235	COG1610	YqeY-like protein
DN405_RS21240	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DN405_RS21245	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DN405_RS21250	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DN405_RS21280	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DN405_RS21285	COG1733	regulation of RNA biosynthetic process
DN405_RS21310	COG1466	dna polymerase III delta subunit
DN405_RS21320	COG0658	competence protein
DN405_RS21320	COG2333	competence protein COMEC
DN405_RS21325	COG2131	deaminase
DN405_RS21330	COG1555	photosystem II stabilization
DN405_RS21330	COG1596	polysaccharide export
DN405_RS21335	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DN405_RS21340	COG2226	methyltransferase
DN405_RS21345	COG0799	negative regulation of ribosome biogenesis
DN405_RS21350	COG1713	HD superfamily hydrolase involved in NAD metabolism
DN405_RS21360	COG1534	Rna-binding protein
DN405_RS21370	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DN405_RS21375	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
DN405_RS21410	COG0778	Nitroreductase
DN405_RS21415	COG2357	RelA SpoT domain protein
DN405_RS21425	COG1785	Belongs to the alkaline phosphatase family
DN405_RS21435	COG2267	carboxylic ester hydrolase activity
DN405_RS21470	COG1404	Belongs to the peptidase S8 family
DN405_RS21475	COG3186	Phenylalanine-4-hydroxylase
DN405_RS21485	COG2514	catechol 2,3-dioxygenase activity
DN405_RS21490	COG2259	Doxx family
DN405_RS21530	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DN405_RS21545	COG1012	belongs to the aldehyde dehydrogenase family
DN405_RS21545	COG1454	alcohol dehydrogenase
DN405_RS21550	COG0626	cystathionine gamma-synthase activity
DN405_RS21555	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DN405_RS21580	COG0768	penicillin binding
DN405_RS21600	COG0826	peptidase U32
DN405_RS21605	COG0826	peptidase U32
DN405_RS21610	COG4122	O-methyltransferase activity
DN405_RS21615	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DN405_RS21645	COG0628	permease
DN405_RS21665	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DN405_RS21680	COG1104	cysteine desulfurase activity
DN405_RS21685	COG1959	2 iron, 2 sulfur cluster binding
DN405_RS21690	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DN405_RS21705	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DN405_RS21725	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DN405_RS21735	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DN405_RS21735	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DN405_RS21740	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DN405_RS21745	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DN405_RS21745	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DN405_RS21755	COG2244	polysaccharide biosynthetic process
DN405_RS21760	COG2323	membrane
DN405_RS21770	COG1862	Preprotein translocase
DN405_RS21800	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DN405_RS21830	COG0157	Belongs to the NadC ModD family
DN405_RS21835	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DN405_RS21840	COG1104	cysteine desulfurase activity
DN405_RS21845	COG1827	regulation of RNA biosynthetic process
DN405_RS21850	COG2258	MOSC domain
DN405_RS21855	COG0077	Prephenate dehydratase
DN405_RS21860	COG0577	efflux transmembrane transporter activity
DN405_RS21865	COG0577	efflux transmembrane transporter activity
DN405_RS21870	COG1136	(ABC) transporter
DN405_RS21875	COG5002	protein histidine kinase activity
DN405_RS21880	COG0745	RESPONSE REGULATOR receiver
DN405_RS21890	COG3290	protein histidine kinase activity
DN405_RS21900	COG2868	ribosomal protein
DN405_RS21910	COG1530	ribonuclease E activity
DN405_RS21915	COG1994	Peptidase M50
DN405_RS21920	COG0739	heme binding
DN405_RS21925	COG2894	cell division
DN405_RS21945	COG1077	Cell shape determining protein MreB Mrl
DN405_RS21965	COG0285	dihydrofolate synthase activity
DN405_RS21980	COG1388	LysM domain
DN405_RS21990	COG0113	porphobilinogen synthase activity
DN405_RS21995	COG1587	Uroporphyrinogen-III synthase
DN405_RS22005	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DN405_RS22015	COG1846	Transcriptional regulator
DN405_RS22020	COG1764	response to oxidative stress
DN405_RS22035	COG0470	DNA polymerase III
DN405_RS22035	COG1067	ATP-dependent peptidase activity
DN405_RS22080	COG0622	Phosphoesterase
DN405_RS22095	COG5401	PFAM Sporulation and spore germination
DN405_RS22110	COG2197	response regulator
DN405_RS22115	COG2233	PERMEase
DN405_RS22120	COG0402	S-adenosylhomocysteine deaminase activity
DN405_RS22125	COG1983	PspC domain protein
DN405_RS22130	COG1396	sequence-specific DNA binding
DN405_RS22135	COG0697	spore germination
DN405_RS22145	COG1959	2 iron, 2 sulfur cluster binding
DN405_RS22150	COG1668	transmembrane transport
DN405_RS22155	COG4152	abc transporter atp-binding protein
DN405_RS22160	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
DN405_RS22165	COG1360	Flagellar Motor Protein
DN405_RS22170	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DN405_RS22175	COG1876	peptidase activity
DN405_RS22180	COG0824	Thioesterase
DN405_RS22185	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DN405_RS22190	COG1053	succinate dehydrogenase
DN405_RS22195	COG2009	succinate dehydrogenase
DN405_RS22200	COG1719	4-vinyl reductase, 4VR
DN405_RS22210	COG3118	belongs to the thioredoxin family
DN405_RS22215	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DN405_RS22220	COG2086	electron transfer activity
DN405_RS22225	COG1024	Enoyl-CoA hydratase
DN405_RS22230	COG1309	transcriptional regulator
DN405_RS22235	COG0318	PFAM AMP-dependent synthetase and ligase
DN405_RS22265	COG2318	DinB family
DN405_RS22290	COG1131	(ABC) transporter
DN405_RS22295	COG2205	protein histidine kinase activity
DN405_RS22300	COG0745	RESPONSE REGULATOR receiver
DN405_RS22305	COG4895	conserved protein (DUF2196)
DN405_RS22310	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DN405_RS22320	COG4509	Sortase family
DN405_RS22325	COG1120	ATPase activity
DN405_RS22340	COG5386	Cell surface protein
DN405_RS22350	COG5386	Cell surface protein
DN405_RS22355	COG1114	Component of the transport system for branched-chain amino acids
DN405_RS22360	COG1187	pseudouridine synthase activity
DN405_RS22370	COG1796	DNA polymerase
DN405_RS22370	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DN405_RS22375	COG1286	toxin biosynthetic process
DN405_RS22415	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DN405_RS22425	COG1418	mRNA catabolic process
DN405_RS22435	COG2814	Major facilitator Superfamily
DN405_RS22440	COG1566	PFAM secretion protein HlyD family protein
DN405_RS22445	COG1309	transcriptional regulator
DN405_RS22450	COG1363	Peptidase, m42
DN405_RS22475	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DN405_RS22490	COG1484	DNA-dependent DNA replication
DN405_RS22495	COG3611	Membrane attachment protein
DN405_RS22505	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
DN405_RS22510	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DN405_RS22520	COG1971	Probably functions as a manganese efflux pump
DN405_RS22530	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DN405_RS22530	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DN405_RS22535	COG5002	protein histidine kinase activity
DN405_RS22540	COG0745	RESPONSE REGULATOR receiver
DN405_RS22560	COG0538	isocitrate dehydrogenase activity
DN405_RS22565	COG0372	Belongs to the citrate synthase family
DN405_RS22580	COG0628	permease
DN405_RS22585	COG3030	protein affecting phage T7 exclusion by the F plasmid
DN405_RS22610	COG1725	Transcriptional regulator
DN405_RS22615	COG0281	malic enzyme
DN405_RS22620	COG0587	DNA-directed DNA polymerase activity
DN405_RS22635	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DN405_RS22650	COG4109	DRTGG domain
DN405_RS22660	COG0006	proline dipeptidase activity
DN405_RS22695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DN405_RS22700	COG0662	Cupin 2, conserved barrel domain protein
DN405_RS22715	COG1028	Short-chain dehydrogenase reductase Sdr
DN405_RS22720	COG0589	response to stress
DN405_RS22760	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DN405_RS22785	COG0827	DNA restriction-modification system
DN405_RS22790	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DN405_RS22795	COG3874	Sporulation protein YtfJ
DN405_RS22810	COG1574	metal-dependent hydrolase with the TIM-barrel fold
DN405_RS22820	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DN405_RS22835	COG1104	cysteine desulfurase activity
DN405_RS22845	COG0583	DNA-binding transcription factor activity
DN405_RS22850	COG0697	spore germination
DN405_RS22855	COG1309	transcriptional regulator
DN405_RS22860	COG1956	GAF domain-containing protein
DN405_RS22865	COG0626	cystathionine gamma-synthase activity
DN405_RS22895	COG0110	maltose O-acetyltransferase activity
DN405_RS22900	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DN405_RS22905	COG0454	-acetyltransferase
DN405_RS22910	COG0517	IMP dehydrogenase activity
DN405_RS22915	COG0123	including yeast histone deacetylase and acetoin utilization protein
DN405_RS22930	COG0745	RESPONSE REGULATOR receiver
DN405_RS22940	COG0666	response to abiotic stimulus
DN405_RS22975	COG1609	Transcriptional regulator
DN405_RS22980	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DN405_RS22980	COG1605	Chorismate mutase
DN405_RS22985	COG4851	CamS sex pheromone cAM373 precursor
DN405_RS22990	COG3118	belongs to the thioredoxin family
DN405_RS23000	COG2309	aminopeptidase activity
DN405_RS23015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DN405_RS23030	COG1674	ftsk spoiiie
DN405_RS23035	COG0860	N-Acetylmuramoyl-L-alanine amidase
DN405_RS23035	COG1388	LysM domain
DN405_RS23045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DN405_RS23055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DN405_RS23060	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
DN405_RS23065	COG1363	Peptidase, m42
DN405_RS23075	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN405_RS23090	COG0510	thiamine kinase activity
DN405_RS23095	COG1523	belongs to the glycosyl hydrolase 13 family
DN405_RS23105	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DN405_RS23110	COG1349	DNA-binding transcription factor activity
DN405_RS23115	COG1187	pseudouridine synthase activity
DN405_RS23120	COG2244	polysaccharide biosynthetic process
DN405_RS23125	COG2081	HI0933 family
DN405_RS23130	COG2814	Major facilitator Superfamily
DN405_RS23140	COG3832	glyoxalase III activity
DN405_RS23165	COG1329	Transcriptional regulator
DN405_RS23190	COG0314	molybdopterin synthase activity
DN405_RS23195	COG1763	Mo-molybdopterin cofactor biosynthetic process
DN405_RS23200	COG0303	'Molybdopterin
DN405_RS23210	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DN405_RS23215	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DN405_RS23240	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DN405_RS23250	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DN405_RS23290	COG2814	Major facilitator Superfamily
DN405_RS23295	COG0475	glutathione-regulated potassium exporter activity
DN405_RS23300	COG0490	domain, Protein
DN405_RS23305	COG0582	viral genome integration into host DNA
DN405_RS23320	COG1136	(ABC) transporter
DN405_RS23340	COG1242	4 iron, 4 sulfur cluster binding
DN405_RS23345	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DN405_RS23370	COG2267	carboxylic ester hydrolase activity
DN405_RS23375	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DN405_RS23380	COG0671	phosphoesterase, PA-phosphatase related
DN405_RS23385	COG0438	transferase activity, transferring glycosyl groups
DN405_RS23405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DN405_RS23480	COG5002	protein histidine kinase activity
DN405_RS23485	COG3852	Histidine kinase
DN405_RS23490	COG0753	catalase activity
DN405_RS23500	COG2267	carboxylic ester hydrolase activity
DN405_RS23505	COG1368	sulfuric ester hydrolase activity
DN405_RS23520	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DN405_RS23525	COG1116	anion transmembrane transporter activity
DN405_RS23530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DN405_RS23555	COG0494	nUDIX hydrolase
DN405_RS23590	COG1854	S-ribosylhomocysteine lyase activity
DN405_RS23600	COG0288	reversible hydration of carbon dioxide
DN405_RS23605	COG1271	oxidase subunit
DN405_RS23610	COG1294	oxidase, subunit
DN405_RS23625	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DN405_RS23645	COG1842	Phage shock protein A
DN405_RS23675	COG5002	protein histidine kinase activity
DN405_RS23680	COG0745	RESPONSE REGULATOR receiver
DN405_RS23705	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DN405_RS23710	COG1597	lipid kinase activity
DN405_RS23775	COG0586	Pfam SNARE associated Golgi protein
DN405_RS23785	COG0577	efflux transmembrane transporter activity
DN405_RS23790	COG1136	(ABC) transporter
DN405_RS23795	COG3708	Transcriptional regulator
DN405_RS23795	COG2207	Transcriptional regulator
DN405_RS23805	COG5658	integral membrane protein
DN405_RS23810	COG0640	Transcriptional regulator
DN405_RS23815	COG0745	RESPONSE REGULATOR receiver
DN405_RS23820	COG2205	protein histidine kinase activity
DN405_RS23825	COG0577	efflux transmembrane transporter activity
DN405_RS23830	COG0577	efflux transmembrane transporter activity
DN405_RS23835	COG1136	(ABC) transporter
DN405_RS23840	COG0577	efflux transmembrane transporter activity
DN405_RS23865	COG2188	Transcriptional regulator
DN405_RS23885	COG3964	amidohydrolase
DN405_RS23905	COG4948	Mandelate Racemase Muconate Lactonizing
DN405_RS23915	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DN405_RS23920	COG0596	Alpha beta hydrolase
DN405_RS23930	COG1169	isochorismate synthase
DN405_RS23935	COG1575	Belongs to the MenA family. Type 1 subfamily
DN405_RS23940	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DN405_RS23960	COG0058	SHG alpha-glucan phosphorylase activity
DN405_RS23970	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DN405_RS23990	COG1404	Belongs to the peptidase S8 family
DN405_RS24005	COG1309	transcriptional regulator
DN405_RS24105	COG0544	peptidyl-prolyl cis-trans isomerase activity
DN405_RS24140	COG1285	pathogenesis
DN405_RS24145	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DN405_RS24165	COG2155	Conserved Protein
DN405_RS24170	COG1098	S1 RNA binding domain
DN405_RS24175	COG0436	Aminotransferase
DN405_RS24180	COG1522	sequence-specific DNA binding
DN405_RS24185	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DN405_RS24190	COG2267	carboxylic ester hydrolase activity
DN405_RS24200	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DN405_RS24215	COG5018	Exonuclease
DN405_RS24220	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DN405_RS24240	COG2050	protein possibly involved in aromatic compounds catabolism
DN405_RS24250	COG1268	BioY protein
DN405_RS24255	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DN405_RS24260	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DN405_RS24280	COG2076	Multidrug Resistance protein
DN405_RS24285	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DN405_RS24295	COG3584	3D domain protein
DN405_RS24310	COG1252	NADH dehydrogenase
DN405_RS24325	COG3708	Transcriptional regulator
DN405_RS24340	COG1683	Conserved Protein
DN405_RS24360	COG0316	Belongs to the HesB IscA family
DN405_RS24375	COG1252	NADH dehydrogenase
DN405_RS24385	COG2274	protein secretion by the type I secretion system
DN405_RS24390	COG0390	transport system, permease component
DN405_RS24395	COG2824	Alkylphosphonate utilization operon protein PhnA
DN405_RS24445	COG4837	Protein of unknown function (DUF1462)
DN405_RS24450	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DN405_RS24460	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DN405_RS24465	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DN405_RS24485	COG1358	cellular component organization or biogenesis
DN405_RS24500	COG2249	NAD(P)H dehydrogenase (quinone) activity
DN405_RS24505	COG0647	UMP catabolic process
DN405_RS24515	COG2445	Protein of unknown function DUF86
DN405_RS24520	COG1494	fructose-1,6-bisphosphatase
DN405_RS24545	COG4470	Protein conserved in bacteria
DN405_RS24555	COG0789	Transcriptional regulator
DN405_RS24560	COG4377	Putative membrane peptidase family (DUF2324)
DN405_RS24585	COG0739	heme binding
DN405_RS24595	COG3377	Domain of unknown function (DUF1805)
DN405_RS24600	COG0737	Belongs to the 5'-nucleotidase family
DN405_RS24610	COG0719	Fe-S assembly protein
DN405_RS24615	COG0822	iron-sulfur transferase activity
DN405_RS24620	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DN405_RS24625	COG0719	Fe-S assembly protein
DN405_RS24630	COG0396	ATPase activity
DN405_RS24635	COG1464	Belongs to the NlpA lipoprotein family
DN405_RS24640	COG1464	Belongs to the NlpA lipoprotein family
DN405_RS24645	COG2011	ABC-type metal ion transport system permease component
DN405_RS24660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DN405_RS24665	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DN405_RS24675	COG1393	Belongs to the ArsC family
DN405_RS24715	COG1309	transcriptional regulator
DN405_RS24720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN405_RS24725	COG1960	acyl-CoA dehydrogenase activity
DN405_RS24730	COG0183	Belongs to the thiolase family
DN405_RS24735	COG1024	Enoyl-CoA hydratase
DN405_RS24735	COG1250	3-hydroxyacyl-CoA dehydrogenase
DN405_RS24745	COG1686	Belongs to the peptidase S11 family
DN405_RS24760	COG0011	TIGRFAM Protein of
DN405_RS24765	COG0840	transmembrane signaling receptor activity
DN405_RS24775	COG2814	Major facilitator Superfamily
DN405_RS24780	COG0531	amino acid
DN405_RS24805	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DN405_RS24845	COG0586	Pfam SNARE associated Golgi protein
DN405_RS24855	COG1376	ErfK ybiS ycfS ynhG family protein
DN405_RS24860	COG0745	RESPONSE REGULATOR receiver
DN405_RS24865	COG5002	protein histidine kinase activity
DN405_RS24895	COG0840	transmembrane signaling receptor activity
DN405_RS24900	COG2151	metal-sulfur cluster biosynthetic enzyme
DN405_RS24905	COG3227	Zinc metalloprotease (Elastase)
DN405_RS24925	COG0586	Pfam SNARE associated Golgi protein
DN405_RS24930	COG0475	glutathione-regulated potassium exporter activity
DN405_RS24935	COG0490	domain, Protein
DN405_RS24945	COG1115	amino acid carrier protein
DN405_RS24950	COG0783	Belongs to the Dps family
DN405_RS24975	COG1611	Belongs to the LOG family
DN405_RS24985	COG1528	Iron-storage protein
DN405_RS24995	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DN405_RS25000	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DN405_RS25005	COG1115	amino acid carrier protein
DN405_RS25010	COG1115	amino acid carrier protein
DN405_RS25015	COG2910	NAD(P)H-binding
DN405_RS25030	COG0656	L-ascorbic acid biosynthetic process
DN405_RS25035	COG2814	Major facilitator Superfamily
DN405_RS25040	COG1733	regulation of RNA biosynthetic process
DN405_RS25050	COG1252	NADH dehydrogenase
DN405_RS25070	COG0840	transmembrane signaling receptor activity
DN405_RS25070	COG3290	protein histidine kinase activity
DN405_RS25100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DN405_RS25190	COG5002	protein histidine kinase activity
DN405_RS25195	COG0745	RESPONSE REGULATOR receiver
DN405_RS25200	COG1136	(ABC) transporter
DN405_RS25220	COG1136	(ABC) transporter
DN405_RS25255	COG0557	exoribonuclease II activity
DN405_RS25260	COG1647	Serine aminopeptidase, S33
DN405_RS25265	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DN405_RS25270	COG1346	cytolysis
DN405_RS25305	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DN405_RS25320	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DN405_RS25345	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DN405_RS25360	COG2323	membrane
DN405_RS25370	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DN405_RS25380	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DN405_RS25390	COG1051	belongs to the nudix hydrolase family
DN405_RS25400	COG0492	ferredoxin-NADP+ reductase activity
DN405_RS25405	COG0457	Tetratricopeptide repeat
DN405_RS25410	COG0110	maltose O-acetyltransferase activity
DN405_RS25430	COG1950	PFAM Membrane protein of
DN405_RS25440	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DN405_RS25445	COG0556	nucleotide-excision repair
DN405_RS25460	COG0789	Transcriptional regulator
DN405_RS25480	COG0583	DNA-binding transcription factor activity
DN405_RS25490	COG0655	NAD(P)H dehydrogenase (quinone) activity
DN405_RS25495	COG0488	(ABC) transporter
DN405_RS25505	COG1132	(ABC) transporter
DN405_RS25510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DN405_RS25515	COG0793	Belongs to the peptidase S41A family
DN405_RS25515	COG3409	Peptidoglycan-binding domain 1 protein
DN405_RS25520	COG2177	Part of the ABC transporter FtsEX involved in
DN405_RS25525	COG2884	Cell division ATP-binding protein ftsE
DN405_RS25550	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DN405_RS25555	COG1278	Cold shock
DN405_RS25560	COG1040	competence protein
DN405_RS25565	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DN405_RS25570	COG0791	NLP P60 protein
DN405_RS25570	COG1388	LysM domain
DN405_RS25575	COG1733	regulation of RNA biosynthetic process
DN405_RS25580	COG1307	EDD domain protein, DegV family
DN405_RS25585	COG1739	Uncharacterized protein family UPF0029
DN405_RS25590	COG1316	TRANSCRIPTIONal
DN405_RS25595	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DN405_RS25600	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DN405_RS25605	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DN405_RS25615	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DN405_RS25615	COG3933	PFAM sigma-54 factor interaction domain-containing protein
DN405_RS25635	COG1486	melibiose metabolic process
DN405_RS25640	COG1447	Phosphotransferase system cellobiose-specific component IIA
DN405_RS25645	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DN405_RS25665	COG1447	Phosphotransferase system cellobiose-specific component IIA
DN405_RS25675	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DN405_RS25680	COG1301	dicarboxylic acid transport
DN405_RS25695	COG1511	domain protein
DN405_RS25700	COG0583	DNA-binding transcription factor activity
DN405_RS25705	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
DN405_RS25710	COG1271	oxidase subunit
DN405_RS25715	COG1294	oxidase, subunit
DN405_RS25720	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DN405_RS25750	COG1620	l-lactate permease
DN405_RS25760	COG2389	metal-binding protein
DN405_RS25775	COG1368	sulfuric ester hydrolase activity
DN405_RS25785	COG0791	NLP P60 protein
DN405_RS25785	COG1388	LysM domain
DN405_RS25790	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DN405_RS25800	COG1215	transferase activity, transferring glycosyl groups
DN405_RS25805	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DN405_RS25815	COG1388	LysM domain
DN405_RS25815	COG3584	3D domain protein
DN405_RS25845	COG4715	Zinc finger, swim domain protein
DN405_RS25850	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DN405_RS25890	COG0577	efflux transmembrane transporter activity
DN405_RS25895	COG1136	(ABC) transporter
DN405_RS25915	COG2271	Major facilitator Superfamily
DN405_RS25930	COG5002	protein histidine kinase activity
DN405_RS25935	COG0745	RESPONSE REGULATOR receiver
DN405_RS25945	COG1316	TRANSCRIPTIONal
DN405_RS25955	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DN405_RS25960	COG1215	transferase activity, transferring glycosyl groups
DN405_RS25980	COG0438	transferase activity, transferring glycosyl groups
DN405_RS25985	COG0438	transferase activity, transferring glycosyl groups
DN405_RS26000	COG1086	Polysaccharide biosynthesis protein
DN405_RS26010	COG1045	serine acetyltransferase
DN405_RS26015	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DN405_RS26020	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DN405_RS26025	COG1086	Polysaccharide biosynthesis protein
DN405_RS26030	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DN405_RS26035	COG4464	protein tyrosine phosphatase activity
DN405_RS26040	COG0489	protein tyrosine kinase activity
DN405_RS26045	COG3944	biosynthesis protein
DN405_RS26050	COG0489	protein tyrosine kinase activity
DN405_RS26065	COG1609	Transcriptional regulator
DN405_RS26075	COG0739	heme binding
DN405_RS26090	COG3279	Response regulator of the LytR AlgR family
DN405_RS26095	COG2385	sporulation resulting in formation of a cellular spore
DN405_RS26110	COG4836	Membrane
DN405_RS26115	COG1007	ATP synthesis coupled electron transport
DN405_RS26120	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DN405_RS26125	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DN405_RS26135	COG0839	Belongs to the complex I subunit 6 family
DN405_RS26155	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DN405_RS26170	COG5001	Diguanylate cyclase
DN405_RS26170	COG3300	MHYT domain
DN405_RS26220	COG0356	it plays a direct role in the translocation of protons across the membrane
DN405_RS26255	COG0698	ribose 5-phosphate isomerase
DN405_RS26270	COG2259	Doxx family
DN405_RS26275	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DN405_RS26290	COG0009	L-threonylcarbamoyladenylate synthase
DN405_RS26330	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DN405_RS26335	COG1494	fructose-1,6-bisphosphatase
DN405_RS26355	COG4821	SIS domain
DN405_RS26365	COG3343	RNA polymerase activity
DN405_RS26375	COG1960	acyl-CoA dehydrogenase activity
DN405_RS26380	COG1960	acyl-CoA dehydrogenase activity
DN405_RS26385	COG1250	3-hydroxyacyl-CoA dehydrogenase
DN405_RS26390	COG0183	Belongs to the thiolase family
DN405_RS26395	COG2181	nitrate reductase activity
DN405_RS26395	COG0247	lactate metabolic process
DN405_RS26400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DN405_RS26410	COG5001	Diguanylate cyclase
DN405_RS26410	COG3300	MHYT domain
DN405_RS26425	COG3227	Zinc metalloprotease (Elastase)
DN405_RS26430	COG2197	response regulator
DN405_RS26435	COG4585	Histidine kinase
DN405_RS26440	COG0842	Transport permease protein
DN405_RS26445	COG1131	(ABC) transporter
DN405_RS26450	COG0024	Methionine aminopeptidase
DN405_RS26460	COG2234	aminopeptidase activity
DN405_RS26485	COG4506	Protein conserved in bacteria
DN405_RS26490	COG1619	proteins homologs of microcin C7 resistance protein MccF
DN405_RS26515	COG2814	Major facilitator Superfamily
DN405_RS26520	COG0789	Transcriptional regulator
DN405_RS26525	COG0584	glycerophosphoryl diester phosphodiesterase
DN405_RS26530	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DN405_RS26540	COG1994	Peptidase M50
DN405_RS26550	COG1078	dGTPase activity
DN405_RS26555	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DN405_RS26560	COG1120	ATPase activity
DN405_RS26565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DN405_RS26570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DN405_RS26590	COG0280	phosphate acetyltransferase
DN405_RS26605	COG3773	Cell wall hydrolase
DN405_RS26615	COG2363	Small membrane protein
DN405_RS26625	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DN405_RS26630	COG2233	PERMEase
DN405_RS26635	COG0561	phosphatase activity
DN405_RS26640	COG2814	Major facilitator Superfamily
DN405_RS26650	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DN405_RS26655	COG1131	(ABC) transporter
DN405_RS26660	COG2755	lipolytic protein G-D-S-L family
DN405_RS26665	COG1609	Transcriptional regulator
DN405_RS26675	COG0460	homoserine dehydrogenase
DN405_RS26685	COG2873	o-acetylhomoserine
DN405_RS26695	COG1011	Hydrolase
DN405_RS26700	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DN405_RS26710	COG2197	response regulator
DN405_RS26715	COG2203	Gaf domain
DN405_RS26715	COG4585	Histidine kinase
DN405_RS26720	COG0351	phosphomethylpyrimidine kinase
DN405_RS26725	COG3706	GGDEF domain
DN405_RS26730	COG2879	small protein
DN405_RS26735	COG1966	Carbon starvation protein
DN405_RS26740	COG3279	Response regulator of the LytR AlgR family
DN405_RS26745	COG0477	Major facilitator Superfamily
DN405_RS26760	COG0438	transferase activity, transferring glycosyl groups
DN405_RS26775	COG0840	transmembrane signaling receptor activity
DN405_RS26785	COG1607	acyl-coa hydrolase
DN405_RS26795	COG1216	Glycosyl transferase, family 2
DN405_RS26810	COG0463	Glycosyl transferase, family 2
DN405_RS26815	COG0488	(ABC) transporter
DN405_RS26820	COG1309	transcriptional regulator
DN405_RS26825	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DN405_RS26830	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DN405_RS26830	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DN405_RS26835	COG0628	permease
DN405_RS26855	COG3275	phosphorelay sensor kinase activity
DN405_RS26860	COG2814	Major facilitator Superfamily
DN405_RS26865	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DN405_RS26870	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
DN405_RS26900	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DN405_RS26905	COG1272	protein, Hemolysin III
DN405_RS26925	COG1164	Oligoendopeptidase f
DN405_RS26935	COG5002	protein histidine kinase activity
DN405_RS26950	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DN405_RS26955	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DN405_RS26960	COG4853	Protein conserved in bacteria
DN405_RS26970	COG5002	protein histidine kinase activity
DN405_RS26975	COG0745	RESPONSE REGULATOR receiver
DN405_RS27005	COG0305	Participates in initiation and elongation during chromosome replication
DN405_RS27015	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
DN405_RS27020	COG4241	membrane
DN405_RS27040	COG0012	GTP binding
DN405_RS27045	COG4481	Protein conserved in bacteria
DN405_RS27050	COG0668	transmembrane transport
DN405_RS27060	COG1475	DNA binding
DN405_RS27065	COG1192	Involved in chromosome partitioning
DN405_RS27090	COG1847	R3H domain protein
DN405_RS27105	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DN405_RS27140	COG0457	Tetratricopeptide repeat
DN405_RS27325	COG0741	lytic transglycosylase activity
DN405_RS27325	COG0791	NLP P60 protein
DN405_RS27395	COG0551	DNA topoisomerase type I activity
DN405_RS27395	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DN405_RS27425	COG1104	cysteine desulfurase activity
DN405_RS27445	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DN405_RS27480	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DN405_RS27535	COG0653	protein targeting
DN405_RS27550	COG4166	transmembrane transport
DN405_RS27580	COG3103	Sh3 type 3 domain protein
DN405_RS27580	COG1388	LysM domain
DN405_RS27580	COG0791	NLP P60 protein
DN405_RS27590	COG1522	sequence-specific DNA binding
DN405_RS27595	COG5632	N-Acetylmuramoyl-L-alanine amidase
DN405_RS27595	COG3409	Peptidoglycan-binding domain 1 protein
DN405_RS27610	COG0456	acetyltransferase
DN405_RS27740	COG1760	l-serine dehydratase
DN405_RS27750	COG0156	8-amino-7-oxononanoate synthase activity
DN405_RS27875	COG0741	lytic transglycosylase activity
DN405_RS27875	COG0791	NLP P60 protein
DN405_RS27905	COG0551	DNA topoisomerase type I activity
DN405_RS27905	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DN405_RS27915	COG5002	protein histidine kinase activity
DN405_RS27945	COG1192	Involved in chromosome partitioning