locus-tag	class	description
CXL14_RS00010	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CXL14_RS00015	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CXL14_RS00035	COG3064	Membrane
CXL14_RS00040	COG2252	PERMEase
CXL14_RS00055	COG2211	Major facilitator Superfamily
CXL14_RS00075	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CXL14_RS00085	COG1305	Transglutaminase-like
CXL14_RS00090	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
CXL14_RS00095	COG0714	Associated with various cellular activities
CXL14_RS00100	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CXL14_RS00105	COG1113	amino acid transport
CXL14_RS00110	COG2132	Multicopper oxidase
CXL14_RS00120	COG0823	Involved in the tonB-independent uptake of proteins
CXL14_RS00125	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CXL14_RS00130	COG1063	alcohol dehydrogenase
CXL14_RS00135	COG1595	DNA-templated transcription, initiation
CXL14_RS00145	COG2755	lipolytic protein G-D-S-L family
CXL14_RS00145	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CXL14_RS00150	COG4260	virion core protein, lumpy skin disease virus
CXL14_RS00155	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CXL14_RS00160	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CXL14_RS00165	COG1842	Phage shock protein A
CXL14_RS00175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXL14_RS00180	COG2211	Major facilitator Superfamily
CXL14_RS00185	COG1063	alcohol dehydrogenase
CXL14_RS00190	COG0457	Tetratricopeptide repeat
CXL14_RS00215	COG1266	CAAX protease self-immunity
CXL14_RS00225	COG0805	protein transport
CXL14_RS00230	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CXL14_RS00245	COG0488	(ABC) transporter
CXL14_RS00250	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CXL14_RS00255	COG0456	acetyltransferase
CXL14_RS00260	COG1214	PFAM Peptidase M22, glycoprotease
CXL14_RS00265	COG0802	atpase or kinase
CXL14_RS00270	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CXL14_RS00310	COG2814	Major facilitator Superfamily
CXL14_RS00315	COG0604	alcohol dehydrogenase
CXL14_RS00320	COG3832	glyoxalase III activity
CXL14_RS00330	COG0531	amino acid
CXL14_RS00335	COG1309	transcriptional regulator
CXL14_RS00340	COG2076	Multidrug Resistance protein
CXL14_RS00345	COG2076	Multidrug Resistance protein
CXL14_RS00350	COG2807	transmembrane transport
CXL14_RS00355	COG2186	Transcriptional regulator
CXL14_RS00360	COG2188	Transcriptional regulator
CXL14_RS00365	COG2814	Major facilitator Superfamily
CXL14_RS00370	COG1388	LysM domain
CXL14_RS00375	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CXL14_RS00390	COG1819	glycosyl
CXL14_RS00395	COG1802	Transcriptional regulator
CXL14_RS00400	COG0473	3-isopropylmalate dehydrogenase activity
CXL14_RS00405	COG2226	methyltransferase
CXL14_RS00410	COG1051	belongs to the nudix hydrolase family
CXL14_RS00415	COG0697	spore germination
CXL14_RS00420	COG4978	Transcriptional regulator
CXL14_RS00420	COG0789	Transcriptional regulator
CXL14_RS00425	COG0456	acetyltransferase
CXL14_RS00430	COG0730	response to heat
CXL14_RS00440	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CXL14_RS00445	COG2814	Major facilitator Superfamily
CXL14_RS00455	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CXL14_RS00460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CXL14_RS00465	COG0488	(ABC) transporter
CXL14_RS00470	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CXL14_RS00475	COG2409	Drug exporters of the RND superfamily
CXL14_RS00480	COG2197	response regulator
CXL14_RS00485	COG4585	Histidine kinase
CXL14_RS00500	COG0738	Major facilitator superfamily
CXL14_RS00510	COG5577	PFAM Coat F domain
CXL14_RS00515	COG1063	alcohol dehydrogenase
CXL14_RS00525	COG5577	PFAM Coat F domain
CXL14_RS00530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CXL14_RS00535	COG0697	spore germination
CXL14_RS00540	COG1309	transcriptional regulator
CXL14_RS00545	COG2814	Major facilitator Superfamily
CXL14_RS00560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CXL14_RS00570	COG0789	Transcriptional regulator
CXL14_RS00575	COG1064	alcohol dehydrogenase
CXL14_RS00590	COG0351	phosphomethylpyrimidine kinase
CXL14_RS00620	COG2318	DinB family
CXL14_RS00650	COG0277	FAD linked oxidase domain protein
CXL14_RS00670	COG0477	Major facilitator Superfamily
CXL14_RS00675	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CXL14_RS00685	COG1917	Cupin 2, conserved barrel domain protein
CXL14_RS00685	COG2207	Transcriptional regulator
CXL14_RS00690	COG1473	amidohydrolase
CXL14_RS00695	COG0814	amino acid
CXL14_RS00700	COG0251	oxidation-reduction process
CXL14_RS00705	COG1802	Transcriptional regulator
CXL14_RS00710	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CXL14_RS00720	COG3621	Patatin-like phospholipase
CXL14_RS00735	COG1794	racemase activity, acting on amino acids and derivatives
CXL14_RS00740	COG0730	response to heat
CXL14_RS00745	COG0425	Belongs to the sulfur carrier protein TusA family
CXL14_RS00750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CXL14_RS00750	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CXL14_RS00755	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CXL14_RS00755	COG0425	Belongs to the sulfur carrier protein TusA family
CXL14_RS00760	COG1054	Belongs to the UPF0176 family
CXL14_RS00765	COG2210	Belongs to the sulfur carrier protein TusA family
CXL14_RS00770	COG1937	Protein conserved in bacteria
CXL14_RS00775	COG1329	Transcriptional regulator
CXL14_RS00780	COG1278	Cold shock
CXL14_RS00790	COG3239	Fatty acid desaturase
CXL14_RS00795	COG1309	transcriptional regulator
CXL14_RS00805	COG2910	NAD(P)H-binding
CXL14_RS00810	COG1959	2 iron, 2 sulfur cluster binding
CXL14_RS00825	COG2030	dehydratase
CXL14_RS00845	COG0477	Major facilitator Superfamily
CXL14_RS00855	COG0457	Tetratricopeptide repeat
CXL14_RS00870	COG0457	Tetratricopeptide repeat
CXL14_RS00930	COG2183	response to ionizing radiation
CXL14_RS00935	COG2208	phosphoserine phosphatase activity
CXL14_RS00940	COG1191	sigma factor activity
CXL14_RS00950	COG1366	Belongs to the anti-sigma-factor antagonist family
CXL14_RS00955	COG2208	phosphoserine phosphatase activity
CXL14_RS00960	COG2172	sigma factor antagonist activity
CXL14_RS00965	COG1366	Belongs to the anti-sigma-factor antagonist family
CXL14_RS00970	COG1366	Belongs to the anti-sigma-factor antagonist family
CXL14_RS00975	COG2337	Toxic component of a toxin-antitoxin (TA) module
CXL14_RS00980	COG0864	Transcriptional regulator
CXL14_RS00985	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CXL14_RS00990	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CXL14_RS01000	COG0705	Rhomboid family
CXL14_RS01005	COG3428	Bacterial PH domain
CXL14_RS01010	COG3402	PFAM membrane-flanked domain
CXL14_RS01015	COG0513	Belongs to the DEAD box helicase family
CXL14_RS01020	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CXL14_RS01030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CXL14_RS01035	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CXL14_RS01050	COG1960	acyl-CoA dehydrogenase activity
CXL14_RS01060	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CXL14_RS01065	COG1131	(ABC) transporter
CXL14_RS01070	COG0628	permease
CXL14_RS01075	COG1301	dicarboxylic acid transport
CXL14_RS01080	COG4565	transcriptional regulatory protein
CXL14_RS01085	COG3290	protein histidine kinase activity
CXL14_RS01090	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CXL14_RS01095	COG3546	catalase activity
CXL14_RS01100	COG2329	Antibiotic biosynthesis monooxygenase
CXL14_RS01105	COG0662	Cupin 2, conserved barrel domain protein
CXL14_RS01110	COG3729	General stress protein
CXL14_RS01115	COG2217	Heavy metal translocating P-type atpase
CXL14_RS01120	COG2076	Multidrug Resistance protein
CXL14_RS01130	COG4876	unkown
CXL14_RS01145	COG1914	H( )-stimulated, divalent metal cation uptake system
CXL14_RS01175	COG0028	Belongs to the TPP enzyme family
CXL14_RS01180	COG0494	nUDIX hydrolase
CXL14_RS01185	COG0531	amino acid
CXL14_RS01195	COG1215	transferase activity, transferring glycosyl groups
CXL14_RS01200	COG5298	Protein conserved in bacteria
CXL14_RS01205	COG3706	GGDEF domain
CXL14_RS01210	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CXL14_RS01215	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CXL14_RS01215	COG0551	DNA topoisomerase type I activity
CXL14_RS01220	COG1522	sequence-specific DNA binding
CXL14_RS01225	COG2814	Major facilitator Superfamily
CXL14_RS01235	COG3871	stress protein (general stress protein 26)
CXL14_RS01240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CXL14_RS01245	COG1917	Cupin 2, conserved barrel domain protein
CXL14_RS01250	COG1028	Short-chain dehydrogenase reductase Sdr
CXL14_RS01255	COG0318	PFAM AMP-dependent synthetase and ligase
CXL14_RS01260	COG3711	transcriptional antiterminator
CXL14_RS01265	COG4989	oxidoreductase activity
CXL14_RS01270	COG0768	penicillin binding
CXL14_RS01275	COG2329	Antibiotic biosynthesis monooxygenase
CXL14_RS01285	COG2755	lipolytic protein G-D-S-L family
CXL14_RS01290	COG1414	Transcriptional regulator
CXL14_RS01295	COG1984	allophanate hydrolase subunit 2
CXL14_RS01300	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CXL14_RS01310	COG1914	H( )-stimulated, divalent metal cation uptake system
CXL14_RS01320	COG0561	phosphatase activity
CXL14_RS01330	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CXL14_RS01340	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXL14_RS01345	COG2213	PTS system mannitol-specific
CXL14_RS01355	COG1349	DNA-binding transcription factor activity
CXL14_RS01360	COG2372	response to copper ion
CXL14_RS01360	COG1276	copper resistance
CXL14_RS01365	COG4549	nuclear export factor GLE1
CXL14_RS01370	COG1028	Short-chain dehydrogenase reductase Sdr
CXL14_RS01375	COG4975	Glucose uptake
CXL14_RS01380	COG1012	belongs to the aldehyde dehydrogenase family
CXL14_RS01385	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CXL14_RS01390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CXL14_RS01395	COG0640	Transcriptional regulator
CXL14_RS01400	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CXL14_RS01405	COG0778	Nitroreductase
CXL14_RS01410	COG1309	transcriptional regulator
CXL14_RS01415	COG2814	Major facilitator Superfamily
CXL14_RS01420	COG4607	ABC-type enterochelin transport system periplasmic component
CXL14_RS01425	COG4604	ABC transporter, ATP-binding protein
CXL14_RS01430	COG4605	iron ion homeostasis
CXL14_RS01435	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CXL14_RS01440	COG0527	aspartate kinase activity
CXL14_RS01455	COG0457	Tetratricopeptide repeat
CXL14_RS01460	COG3850	Histidine kinase
CXL14_RS01460	COG5002	protein histidine kinase activity
CXL14_RS01465	COG0745	RESPONSE REGULATOR receiver
CXL14_RS01470	COG0577	efflux transmembrane transporter activity
CXL14_RS01475	COG1136	(ABC) transporter
CXL14_RS01480	COG2079	MmgE PrpD family protein
CXL14_RS01485	COG1473	amidohydrolase
CXL14_RS01490	COG1126	abc transporter atp-binding protein
CXL14_RS01495	COG0765	amino acid transport
CXL14_RS01500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXL14_RS01505	COG0456	acetyltransferase
CXL14_RS01510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CXL14_RS01515	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CXL14_RS01525	COG0697	spore germination
CXL14_RS01535	COG5434	Belongs to the glycosyl hydrolase 28 family
CXL14_RS01540	COG3104	oligopeptide transport
CXL14_RS01555	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CXL14_RS01560	COG0163	prenyltransferase activity
CXL14_RS01565	COG0583	DNA-binding transcription factor activity
CXL14_RS01570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXL14_RS01575	COG0765	amino acid transport
CXL14_RS01580	COG1126	abc transporter atp-binding protein
CXL14_RS01585	COG2364	Membrane
CXL14_RS01600	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CXL14_RS01605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXL14_RS01610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXL14_RS01615	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXL14_RS01625	COG1733	regulation of RNA biosynthetic process
CXL14_RS01630	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CXL14_RS01635	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CXL14_RS01640	COG3209	COG3209 Rhs family protein
CXL14_RS01650	COG2723	6-phospho-beta-galactosidase activity
CXL14_RS01660	COG1714	RDD family
CXL14_RS01665	COG1063	alcohol dehydrogenase
CXL14_RS01670	COG0523	cobalamin synthesis protein
CXL14_RS01675	COG2223	nitrite transmembrane transporter activity
CXL14_RS01680	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CXL14_RS01685	COG0243	molybdopterin cofactor binding
CXL14_RS01690	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CXL14_RS01695	COG2146	nitrite reductase [NAD(P)H] activity
CXL14_RS01700	COG1587	Uroporphyrinogen-III synthase
CXL14_RS01700	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CXL14_RS01710	COG2508	Transcriptional regulator
CXL14_RS01715	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CXL14_RS01720	COG1012	belongs to the aldehyde dehydrogenase family
CXL14_RS01725	COG0506	proline dehydrogenase activity
CXL14_RS01730	COG3541	Predicted nucleotidyltransferase
CXL14_RS01735	COG3458	cephalosporin-C deacetylase activity
CXL14_RS01740	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CXL14_RS01745	COG2271	Major facilitator Superfamily
CXL14_RS01755	COG1660	Displays ATPase and GTPase activities
CXL14_RS01770	COG3665	Urea carboxylase-associated protein
CXL14_RS01775	COG1113	amino acid transport
CXL14_RS01780	COG3403	YqcI/YcgG family
CXL14_RS01785	COG1280	lysine exporter protein (LysE YggA)
CXL14_RS01790	COG1846	Transcriptional regulator
CXL14_RS01795	COG2814	Major facilitator Superfamily
CXL14_RS01805	COG0366	Alpha amylase catalytic
CXL14_RS01815	COG1288	antiporter activity
CXL14_RS01820	COG1473	amidohydrolase
CXL14_RS01825	COG2113	Glycine betaine
CXL14_RS01830	COG4176	ABC-type proline glycine betaine transport system permease component
CXL14_RS01835	COG0517	IMP dehydrogenase activity
CXL14_RS01835	COG4175	Glycine betaine
CXL14_RS01840	COG0477	Major facilitator Superfamily
CXL14_RS01845	COG3853	Toxic anion resistance protein (TelA)
CXL14_RS01855	COG0861	Integral membrane protein TerC family
CXL14_RS01860	COG2310	stress, protein
CXL14_RS01865	COG2310	stress, protein
CXL14_RS01870	COG2310	stress, protein
CXL14_RS01875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CXL14_RS01880	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CXL14_RS01885	COG1121	(ABC) transporter
CXL14_RS01890	COG0803	Belongs to the bacterial solute-binding protein 9 family
CXL14_RS01895	COG0366	Alpha amylase catalytic
CXL14_RS01900	COG1028	Short-chain dehydrogenase reductase Sdr
CXL14_RS01905	COG0457	Tetratricopeptide repeat
CXL14_RS01910	COG1876	peptidase activity
CXL14_RS01915	COG1595	DNA-templated transcription, initiation
CXL14_RS01920	COG1595	DNA-templated transcription, initiation
CXL14_RS01930	COG0667	Aldo Keto reductase
CXL14_RS01935	COG3012	SEC-C Motif Domain Protein
CXL14_RS01935	COG1405	negative regulation of cell septum assembly
CXL14_RS01940	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CXL14_RS01945	COG0252	asparaginase activity
CXL14_RS01950	COG1309	transcriptional regulator
CXL14_RS01955	COG0477	Major facilitator Superfamily
CXL14_RS01960	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CXL14_RS01970	COG0805	protein transport
CXL14_RS01975	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CXL14_RS01980	COG3540	Alkaline phosphatase
CXL14_RS01990	COG3773	Cell wall hydrolase
CXL14_RS02010	COG3173	Aminoglycoside phosphotransferase
CXL14_RS02015	COG0784	Response regulator, receiver
CXL14_RS02020	COG4191	Histidine kinase
CXL14_RS02025	COG2066	Belongs to the glutaminase family
CXL14_RS02030	COG1115	amino acid carrier protein
CXL14_RS02035	COG2040	homocysteine
CXL14_RS02040	COG0833	amino acid
CXL14_RS02045	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CXL14_RS02050	COG1301	dicarboxylic acid transport
CXL14_RS02065	COG0688	phosphatidylethanolamine metabolic process
CXL14_RS02070	COG0586	Pfam SNARE associated Golgi protein
CXL14_RS02075	COG1183	phosphatidylcholine synthase activity
CXL14_RS02085	COG0371	Dehydrogenase
CXL14_RS02100	COG3409	Peptidoglycan-binding domain 1 protein
CXL14_RS02110	COG2368	4-hydroxyphenylacetate
CXL14_RS02125	COG2271	Major facilitator Superfamily
CXL14_RS02130	COG0584	glycerophosphoryl diester phosphodiesterase
CXL14_RS02145	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CXL14_RS02150	COG0531	amino acid
CXL14_RS02190	COG1131	(ABC) transporter
CXL14_RS02195	COG2197	response regulator
CXL14_RS02200	COG4585	Histidine kinase
CXL14_RS02205	COG1011	Hydrolase
CXL14_RS02210	COG1113	amino acid transport
CXL14_RS02215	COG1846	Transcriptional regulator
CXL14_RS02220	COG1380	Effector of murein hydrolase LrgA
CXL14_RS02225	COG1346	cytolysis
CXL14_RS02270	COG4856	YbbR-like protein
CXL14_RS02275	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CXL14_RS02280	COG5662	AntiSigma factor
CXL14_RS02285	COG1595	DNA-templated transcription, initiation
CXL14_RS02315	COG1683	Conserved Protein
CXL14_RS02320	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CXL14_RS02330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXL14_RS02330	COG1263	PTS System
CXL14_RS02335	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CXL14_RS02340	COG1472	Belongs to the glycosyl hydrolase 3 family
CXL14_RS02345	COG3876	Protein conserved in bacteria
CXL14_RS02350	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CXL14_RS02350	COG2207	Transcriptional regulator
CXL14_RS02355	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CXL14_RS02360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CXL14_RS02365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CXL14_RS02370	COG2819	hydrolase of the alpha beta superfamily
CXL14_RS02375	COG0385	Bile acid
CXL14_RS02380	COG0659	secondary active sulfate transmembrane transporter activity
CXL14_RS02395	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CXL14_RS02400	COG0738	Major facilitator superfamily
CXL14_RS02460	COG0726	polysaccharide deacetylase
CXL14_RS02465	COG2194	sulfuric ester hydrolase activity
CXL14_RS02475	COG0489	protein tyrosine kinase activity
CXL14_RS02480	COG0860	N-Acetylmuramoyl-L-alanine amidase
CXL14_RS02490	COG2318	DinB family
CXL14_RS02495	COG2226	methyltransferase
CXL14_RS02515	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CXL14_RS02520	COG1122	ATPase activity
CXL14_RS02525	COG1122	ATPase activity
CXL14_RS02550	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CXL14_RS02565	COG0024	Methionine aminopeptidase
CXL14_RS02575	COG0201	protein transport
CXL14_RS02590	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CXL14_RS02685	COG0596	Alpha beta hydrolase
CXL14_RS02710	COG1358	cellular component organization or biogenesis
CXL14_RS02725	COG2813	Specifically methylates the guanine in position
CXL14_RS02750	COG0250	Participates in transcription elongation, termination and antitermination
CXL14_RS02755	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CXL14_RS02765	COG1595	DNA-templated transcription, initiation
CXL14_RS02770	COG3688	RNA-binding protein containing a PIN domain
CXL14_RS02775	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CXL14_RS02780	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CXL14_RS02790	COG1045	serine acetyltransferase
CXL14_RS02810	COG4956	integral membrane protein (PIN domain superfamily)
CXL14_RS02815	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CXL14_RS02820	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CXL14_RS02825	COG0542	response to heat
CXL14_RS02835	COG3880	PFAM UvrB UvrC protein
CXL14_RS02840	COG4463	regulation of RNA biosynthetic process
CXL14_RS02925	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CXL14_RS02930	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CXL14_RS02935	COG1396	sequence-specific DNA binding
CXL14_RS02940	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CXL14_RS02945	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CXL14_RS02950	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CXL14_RS02955	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CXL14_RS02960	COG0512	Glutamine amidotransferase of anthranilate synthase
CXL14_RS02965	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CXL14_RS02970	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CXL14_RS02975	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CXL14_RS02990	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CXL14_RS02995	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CXL14_RS03000	COG0037	tRNA processing
CXL14_RS03005	COG0515	serine threonine protein kinase
CXL14_RS03010	COG2304	oxidoreductase activity
CXL14_RS03015	COG2208	phosphoserine phosphatase activity
CXL14_RS03030	COG1098	S1 RNA binding domain
CXL14_RS03035	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CXL14_RS03050	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CXL14_RS03055	COG3956	TIGRFAM MazG family protein
CXL14_RS03060	COG2244	polysaccharide biosynthetic process
CXL14_RS03065	COG2002	toxin-antitoxin pair type II binding
CXL14_RS03070	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CXL14_RS03090	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CXL14_RS03105	COG0251	oxidation-reduction process
CXL14_RS03110	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CXL14_RS03125	COG4466	Protein conserved in bacteria
CXL14_RS03135	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CXL14_RS03140	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CXL14_RS03145	COG3584	3D domain protein
CXL14_RS03145	COG3583	domain protein
CXL14_RS03150	COG0084	hydrolase, TatD family'
CXL14_RS03155	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CXL14_RS03155	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CXL14_RS03160	COG2002	toxin-antitoxin pair type II binding
CXL14_RS03165	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CXL14_RS03175	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CXL14_RS03185	COG1774	PSP1 C-terminal conserved region
CXL14_RS03190	COG0470	DNA polymerase III
CXL14_RS03195	COG1728	Protein conserved in bacteria
CXL14_RS03200	COG3870	Protein conserved in bacteria
CXL14_RS03210	COG1982	Orn Lys Arg decarboxylase major
CXL14_RS03215	COG3853	Toxic anion resistance protein (TelA)
CXL14_RS03220	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
CXL14_RS03265	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CXL14_RS03270	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CXL14_RS03275	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CXL14_RS03285	COG0590	tRNA wobble adenosine to inosine editing
CXL14_RS03290	COG1335	isochorismatase
CXL14_RS03295	COG1388	LysM domain
CXL14_RS03295	COG3858	chitin binding
CXL14_RS03300	COG1428	Deoxynucleoside kinase
CXL14_RS03305	COG1428	Deoxynucleoside kinase
CXL14_RS03315	COG1929	Belongs to the glycerate kinase type-1 family
CXL14_RS03335	COG1686	Belongs to the peptidase S11 family
CXL14_RS03340	COG0517	IMP dehydrogenase activity
CXL14_RS03340	COG0516	GMP reductase activity
CXL14_RS03375	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CXL14_RS03380	COG0187	DNA topoisomerase II activity
CXL14_RS03395	COG2501	S4 domain
CXL14_RS03400	COG0592	DNA-directed DNA polymerase activity
CXL14_RS03420	COG0706	membrane insertase activity
CXL14_RS03425	COG1847	R3H domain protein
CXL14_RS03450	COG1192	Involved in chromosome partitioning
CXL14_RS03455	COG1475	DNA binding
CXL14_RS03470	COG3949	Membrane
CXL14_RS03475	COG4481	Protein conserved in bacteria
CXL14_RS03480	COG0243	molybdopterin cofactor binding
CXL14_RS03485	COG0012	GTP binding
CXL14_RS03495	COG0629	single-stranded DNA binding
CXL14_RS03505	COG2169	Transcriptional regulator
CXL14_RS03510	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CXL14_RS03520	COG1609	Transcriptional regulator
CXL14_RS03525	COG0346	lactoylglutathione lyase activity
CXL14_RS03530	COG2814	Major facilitator Superfamily
CXL14_RS03530	COG0477	Major facilitator Superfamily
CXL14_RS03535	COG1266	CAAX protease self-immunity
CXL14_RS03540	COG1331	Highly conserved protein containing a thioredoxin domain
CXL14_RS03550	COG1078	dGTPase activity
CXL14_RS03555	COG0697	spore germination
CXL14_RS03560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CXL14_RS03570	COG1404	Belongs to the peptidase S8 family
CXL14_RS03600	COG0546	phosphoglycolate phosphatase activity
CXL14_RS03610	COG2153	protein acetylation
CXL14_RS03615	COG1846	Transcriptional regulator
CXL14_RS03620	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CXL14_RS03625	COG1846	Transcriptional regulator
CXL14_RS03630	COG0778	Nitroreductase
CXL14_RS03640	COG0697	spore germination
CXL14_RS03645	COG2211	Major facilitator Superfamily
CXL14_RS03650	COG2318	DinB family
CXL14_RS03655	COG1802	Transcriptional regulator
CXL14_RS03660	COG1621	beta-fructofuranosidase activity
CXL14_RS03665	COG1621	beta-fructofuranosidase activity
CXL14_RS03670	COG0697	spore germination
CXL14_RS03680	COG1733	regulation of RNA biosynthetic process
CXL14_RS03685	COG5577	PFAM Coat F domain
CXL14_RS03695	COG4241	membrane
CXL14_RS03700	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CXL14_RS03710	COG2112	serine threonine protein kinase
CXL14_RS03720	COG0438	transferase activity, transferring glycosyl groups
CXL14_RS03725	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CXL14_RS03735	COG0297	glycogen (starch) synthase activity
CXL14_RS03740	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CXL14_RS03745	COG3093	addiction module antidote protein HigA
CXL14_RS03760	COG0305	Participates in initiation and elongation during chromosome replication
CXL14_RS03765	COG0346	lactoylglutathione lyase activity
CXL14_RS03800	COG0745	RESPONSE REGULATOR receiver
CXL14_RS03805	COG5002	protein histidine kinase activity
CXL14_RS03810	COG4863	YycH protein
CXL14_RS03815	COG4853	Protein conserved in bacteria
CXL14_RS03820	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CXL14_RS03825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CXL14_RS03835	COG0745	RESPONSE REGULATOR receiver
CXL14_RS03840	COG5002	protein histidine kinase activity
CXL14_RS03840	COG3850	Histidine kinase
CXL14_RS03845	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CXL14_RS03860	COG0488	(ABC) transporter
CXL14_RS03870	COG3829	transcription factor binding
CXL14_RS03875	COG0640	Transcriptional regulator
CXL14_RS03880	COG5658	integral membrane protein
CXL14_RS03885	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CXL14_RS03890	COG0833	amino acid
CXL14_RS03895	COG0010	Belongs to the arginase family
CXL14_RS03900	COG0457	Tetratricopeptide repeat
CXL14_RS03905	COG0456	acetyltransferase
CXL14_RS03910	COG0667	Aldo Keto reductase
CXL14_RS03915	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CXL14_RS03960	COG0210	DNA helicase
CXL14_RS03990	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CXL14_RS03995	COG2068	MobA-Related Protein
CXL14_RS04010	COG2080	2 iron, 2 sulfur cluster binding
CXL14_RS04020	COG1113	amino acid transport
CXL14_RS04025	COG3177	Filamentation induced by cAMP protein fic
CXL14_RS04030	COG3634	alkyl hydroperoxide reductase activity
CXL14_RS04035	COG0450	alkyl hydroperoxide reductase
CXL14_RS04045	COG1714	RDD family
CXL14_RS04055	COG0640	Transcriptional regulator
CXL14_RS04065	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CXL14_RS04070	COG1012	belongs to the aldehyde dehydrogenase family
CXL14_RS04075	COG1309	transcriptional regulator
CXL14_RS04085	COG3239	Fatty acid desaturase
CXL14_RS04090	COG4585	Histidine kinase
CXL14_RS04095	COG2197	response regulator
CXL14_RS04100	COG1028	Short-chain dehydrogenase reductase Sdr
CXL14_RS04115	COG2814	Major facilitator Superfamily
CXL14_RS04120	COG0667	Aldo Keto reductase
CXL14_RS04125	COG1349	DNA-binding transcription factor activity
CXL14_RS04155	COG2814	Major facilitator Superfamily
CXL14_RS04165	COG1082	Xylose isomerase domain protein TIM barrel
CXL14_RS04195	COG0745	RESPONSE REGULATOR receiver
CXL14_RS04220	COG0745	RESPONSE REGULATOR receiver
CXL14_RS04225	COG2205	protein histidine kinase activity
CXL14_RS04230	COG0745	RESPONSE REGULATOR receiver
CXL14_RS04235	COG2205	protein histidine kinase activity
CXL14_RS04240	COG1136	(ABC) transporter
CXL14_RS04245	COG0577	efflux transmembrane transporter activity
CXL14_RS04250	COG5294	Protein conserved in bacteria
CXL14_RS04255	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CXL14_RS04285	COG0561	phosphatase activity
CXL14_RS04290	COG2390	Transcriptional regulator
CXL14_RS04300	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CXL14_RS04305	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CXL14_RS04310	COG0833	amino acid
CXL14_RS04315	COG0010	Belongs to the arginase family
CXL14_RS04340	COG3507	Belongs to the glycosyl hydrolase 43 family
CXL14_RS04345	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
CXL14_RS04350	COG0494	nUDIX hydrolase
CXL14_RS04360	COG0589	response to stress
CXL14_RS04365	COG0697	spore germination
CXL14_RS04375	COG3209	COG3209 Rhs family protein
CXL14_RS04425	COG0513	Belongs to the DEAD box helicase family
CXL14_RS04430	COG2270	Major facilitator Superfamily
CXL14_RS04435	COG3711	transcriptional antiterminator
CXL14_RS04440	COG2273	Hydrolase Family 16
CXL14_RS04445	COG2851	Citrate transporter
CXL14_RS04450	COG0753	catalase activity
CXL14_RS04450	COG0693	protein deglycase activity
CXL14_RS04470	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CXL14_RS04475	COG0500	methyltransferase
CXL14_RS04480	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CXL14_RS04485	COG4894	glucomannan catabolic process
CXL14_RS04495	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CXL14_RS04505	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CXL14_RS04510	COG2508	Transcriptional regulator
CXL14_RS04515	COG3842	ATPase activity
CXL14_RS04520	COG0726	polysaccharide deacetylase
CXL14_RS04525	COG3493	citrate carrier protein
CXL14_RS04530	COG1271	oxidase subunit
CXL14_RS04535	COG1294	oxidase, subunit
CXL14_RS04540	COG4988	ABC transporter
CXL14_RS04545	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CXL14_RS04550	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CXL14_RS04555	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CXL14_RS04560	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CXL14_RS04565	COG0753	catalase activity
CXL14_RS04575	COG1482	cell wall glycoprotein biosynthetic process
CXL14_RS04580	COG1940	carbohydrate kinase activity
CXL14_RS04585	COG2723	6-phospho-beta-galactosidase activity
CXL14_RS04590	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CXL14_RS04595	COG1447	Phosphotransferase system cellobiose-specific component IIA
CXL14_RS04600	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CXL14_RS04605	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CXL14_RS04610	COG0640	Transcriptional regulator
CXL14_RS04620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CXL14_RS04625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CXL14_RS04640	COG3711	transcriptional antiterminator
CXL14_RS04640	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXL14_RS04645	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CXL14_RS04650	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CXL14_RS04655	COG1447	Phosphotransferase system cellobiose-specific component IIA
CXL14_RS04660	COG1486	melibiose metabolic process
CXL14_RS04665	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CXL14_RS04670	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CXL14_RS04680	COG1696	Membrane protein involved in D-alanine export
CXL14_RS04705	COG1575	Belongs to the MenA family. Type 1 subfamily
CXL14_RS04710	COG2357	RelA SpoT domain protein
CXL14_RS04715	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CXL14_RS04720	COG1846	Transcriptional regulator
CXL14_RS04725	COG1442	glycosyl transferase family 8
CXL14_RS04730	COG1404	Belongs to the peptidase S8 family
CXL14_RS04735	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CXL14_RS04740	COG0346	lactoylglutathione lyase activity
CXL14_RS04745	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CXL14_RS04750	COG5504	Zn-dependent protease
CXL14_RS04755	COG0789	Transcriptional regulator
CXL14_RS04760	COG4895	conserved protein (DUF2196)
CXL14_RS04765	COG1346	cytolysis
CXL14_RS04775	COG0583	DNA-binding transcription factor activity
CXL14_RS04790	COG2822	iron ion transport
CXL14_RS04795	COG2837	iron assimilation
CXL14_RS04800	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CXL14_RS04820	COG1309	transcriptional regulator
CXL14_RS04825	COG2246	polysaccharide biosynthetic process
CXL14_RS04830	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CXL14_RS04835	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CXL14_RS04840	COG2261	transglycosylase associated protein
CXL14_RS04845	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CXL14_RS04850	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CXL14_RS04870	COG0454	-acetyltransferase
CXL14_RS04875	COG0772	Belongs to the SEDS family
CXL14_RS04880	COG0778	Nitroreductase
CXL14_RS04885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CXL14_RS04890	COG1404	Belongs to the peptidase S8 family
CXL14_RS04900	COG3711	transcriptional antiterminator
CXL14_RS04905	COG1263	PTS System
CXL14_RS04905	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXL14_RS04910	COG1621	beta-fructofuranosidase activity
CXL14_RS04920	COG0351	phosphomethylpyrimidine kinase
CXL14_RS04925	COG1695	Transcriptional regulator
CXL14_RS04940	COG1216	Glycosyl transferase, family 2
CXL14_RS04955	COG2233	PERMEase
CXL14_RS04960	COG2363	Small membrane protein
CXL14_RS04970	COG0463	Glycosyl transferase, family 2
CXL14_RS04975	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CXL14_RS04980	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CXL14_RS04985	COG0456	acetyltransferase
CXL14_RS04990	COG2089	acid synthase
CXL14_RS04995	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
CXL14_RS05000	COG3980	spore coat polysaccharide biosynthesis protein
CXL14_RS05005	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CXL14_RS05010	COG1088	dTDP-glucose 4,6-dehydratase activity
CXL14_RS05015	COG1091	dTDP-4-dehydrorhamnose reductase activity
CXL14_RS05020	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CXL14_RS05025	COG1131	(ABC) transporter
CXL14_RS05040	COG0745	RESPONSE REGULATOR receiver
CXL14_RS05045	COG2205	protein histidine kinase activity
CXL14_RS05050	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CXL14_RS05055	COG1012	belongs to the aldehyde dehydrogenase family
CXL14_RS05060	COG4187	Peptidase family M20/M25/M40
CXL14_RS05065	COG0833	amino acid
CXL14_RS05070	COG2814	Major facilitator Superfamily
CXL14_RS05075	COG2814	Major facilitator Superfamily
CXL14_RS05105	COG0436	Aminotransferase
CXL14_RS05110	COG1028	Short-chain dehydrogenase reductase Sdr
CXL14_RS05120	COG0280	phosphate acetyltransferase
CXL14_RS05125	COG2855	membrane
CXL14_RS05130	COG0583	DNA-binding transcription factor activity
CXL14_RS05160	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CXL14_RS05165	COG1131	(ABC) transporter
CXL14_RS05175	COG1695	Transcriptional regulator
CXL14_RS05190	COG1078	dGTPase activity
CXL14_RS05195	COG3465	dGTPase activity
CXL14_RS05200	COG0531	amino acid
CXL14_RS05210	COG1846	Transcriptional regulator
CXL14_RS05215	COG1942	4-Oxalocrotonate Tautomerase
CXL14_RS05220	COG1994	Peptidase M50
CXL14_RS05235	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CXL14_RS05240	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CXL14_RS05245	COG0010	Belongs to the arginase family
CXL14_RS05290	COG0457	Tetratricopeptide repeat
CXL14_RS05295	COG4506	Protein conserved in bacteria
CXL14_RS05305	COG2223	nitrite transmembrane transporter activity
CXL14_RS05310	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CXL14_RS05320	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CXL14_RS05325	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CXL14_RS05330	COG1140	nitrate reductase beta subunit
CXL14_RS05335	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CXL14_RS05340	COG2181	nitrate reductase activity
CXL14_RS05350	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CXL14_RS05355	COG1132	(ABC) transporter
CXL14_RS05370	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CXL14_RS05375	COG0247	lactate metabolic process
CXL14_RS05375	COG2181	nitrate reductase activity
CXL14_RS05390	COG4821	SIS domain
CXL14_RS05395	COG2204	response regulator
CXL14_RS05400	COG0191	fructose-bisphosphate aldolase activity
CXL14_RS05410	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CXL14_RS05415	COG1494	fructose-1,6-bisphosphatase
CXL14_RS05420	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CXL14_RS05435	COG0281	malic enzyme
CXL14_RS05440	COG0679	Auxin Efflux Carrier
CXL14_RS05445	COG0789	Transcriptional regulator
CXL14_RS05450	COG0346	lactoylglutathione lyase activity
CXL14_RS05455	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CXL14_RS05460	COG2890	protein-(glutamine-N5) methyltransferase activity
CXL14_RS05480	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CXL14_RS05485	COG0009	L-threonylcarbamoyladenylate synthase
CXL14_RS05495	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CXL14_RS05500	COG0698	ribose 5-phosphate isomerase
CXL14_RS05570	COG4836	Membrane
CXL14_RS05580	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CXL14_RS05585	COG2385	sporulation resulting in formation of a cellular spore
CXL14_RS05590	COG2304	oxidoreductase activity
CXL14_RS05595	COG2304	oxidoreductase activity
CXL14_RS05600	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CXL14_RS05610	COG0457	Tetratricopeptide repeat
CXL14_RS05615	COG1994	Peptidase M50
CXL14_RS05625	COG0831	urea catabolic process
CXL14_RS05640	COG1959	2 iron, 2 sulfur cluster binding
CXL14_RS05650	COG0726	polysaccharide deacetylase
CXL14_RS05660	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CXL14_RS05675	COG1247	-acetyltransferase
CXL14_RS05680	COG0739	heme binding
CXL14_RS05690	COG0671	phosphoesterase, PA-phosphatase related
CXL14_RS05695	COG0772	Belongs to the SEDS family
CXL14_RS05700	COG0347	Belongs to the P(II) protein family
CXL14_RS05705	COG0004	ammonium transporteR
CXL14_RS05710	COG1335	isochorismatase
CXL14_RS05715	COG0477	Major facilitator Superfamily
CXL14_RS05720	COG1953	Uracil, thiamine, allantoin
CXL14_RS05725	COG2814	Major facilitator Superfamily
CXL14_RS05730	COG1846	Transcriptional regulator
CXL14_RS05735	COG1609	Transcriptional regulator
CXL14_RS05740	COG1077	Cell shape determining protein MreB Mrl
CXL14_RS05745	COG4786	Flagellar basal body rod
CXL14_RS05750	COG4786	Flagellar basal body rod
CXL14_RS05755	COG0457	Tetratricopeptide repeat
CXL14_RS05780	COG0629	single-stranded DNA binding
CXL14_RS05785	COG1349	DNA-binding transcription factor activity
CXL14_RS05790	COG0561	phosphatase activity
CXL14_RS05795	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CXL14_RS05800	COG4715	Zinc finger, swim domain protein
CXL14_RS05815	COG3944	biosynthesis protein
CXL14_RS05820	COG0489	protein tyrosine kinase activity
CXL14_RS05825	COG4464	protein tyrosine phosphatase activity
CXL14_RS05830	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CXL14_RS05835	COG3878	Protein conserved in bacteria
CXL14_RS05850	COG5444	nuclease activity
CXL14_RS05885	COG0583	DNA-binding transcription factor activity
CXL14_RS05890	COG0655	NAD(P)H dehydrogenase (quinone) activity
CXL14_RS05900	COG2059	Chromate
CXL14_RS05905	COG2059	Chromate
CXL14_RS05910	COG1522	sequence-specific DNA binding
CXL14_RS05915	COG0405	Gamma-glutamyltransferase
CXL14_RS05925	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CXL14_RS05935	COG5337	Spore coat protein CotH
CXL14_RS05950	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CXL14_RS05955	COG0583	DNA-binding transcription factor activity
CXL14_RS05960	COG0028	Belongs to the TPP enzyme family
CXL14_RS05965	COG3527	Alpha-acetolactate decarboxylase
CXL14_RS05970	COG2249	NAD(P)H dehydrogenase (quinone) activity
CXL14_RS05975	COG3103	Sh3 type 3 domain protein
CXL14_RS05980	COG1879	ABC-type sugar transport system periplasmic component
CXL14_RS05985	COG1172	Belongs to the binding-protein-dependent transport system permease family
CXL14_RS05990	COG1129	ABC transporter
CXL14_RS06000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXL14_RS06005	COG1609	Transcriptional regulator
CXL14_RS06015	COG0814	amino acid
CXL14_RS06020	COG0697	spore germination
CXL14_RS06030	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CXL14_RS06040	COG2843	Capsule synthesis protein
CXL14_RS06050	COG0791	NLP P60 protein
CXL14_RS06055	COG2433	Pfam Transposase IS66
CXL14_RS06060	COG0561	phosphatase activity
CXL14_RS06065	COG1316	TRANSCRIPTIONal
CXL14_RS06070	COG2814	Major facilitator Superfamily
CXL14_RS06075	COG1215	transferase activity, transferring glycosyl groups
CXL14_RS06085	COG0814	amino acid
CXL14_RS06090	COG0697	spore germination
CXL14_RS06095	COG1482	cell wall glycoprotein biosynthetic process
CXL14_RS06100	COG4193	domain, Protein
CXL14_RS06105	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CXL14_RS06110	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CXL14_RS06115	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CXL14_RS06125	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CXL14_RS06130	COG1682	transport, permease protein
CXL14_RS06135	COG1134	teichoic acid transport
CXL14_RS06140	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CXL14_RS06145	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CXL14_RS06150	COG1316	TRANSCRIPTIONal
CXL14_RS06160	COG2247	cell wall binding repeat
CXL14_RS06160	COG2385	sporulation resulting in formation of a cellular spore
CXL14_RS06165	COG2247	cell wall binding repeat
CXL14_RS06165	COG0860	N-Acetylmuramoyl-L-alanine amidase
CXL14_RS06175	COG2244	polysaccharide biosynthetic process
CXL14_RS06180	COG0297	glycogen (starch) synthase activity
CXL14_RS06180	COG0438	transferase activity, transferring glycosyl groups
CXL14_RS06185	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CXL14_RS06190	COG3307	-O-antigen
CXL14_RS06195	COG3206	protein involved in exopolysaccharide biosynthesis
CXL14_RS06200	COG1215	transferase activity, transferring glycosyl groups
CXL14_RS06205	COG0438	transferase activity, transferring glycosyl groups
CXL14_RS06210	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CXL14_RS06215	COG1316	TRANSCRIPTIONal
CXL14_RS06220	COG1739	Uncharacterized protein family UPF0029
CXL14_RS06225	COG4585	Histidine kinase
CXL14_RS06230	COG2197	response regulator
CXL14_RS06235	COG1307	EDD domain protein, DegV family
CXL14_RS06240	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CXL14_RS06250	COG1040	competence protein
CXL14_RS06260	COG2747	anti-sigma28 factor FlgM
CXL14_RS06265	COG3418	PFAM FlgN family protein
CXL14_RS06270	COG4786	Flagellar basal body rod
CXL14_RS06270	COG1256	bacterial-type flagellum assembly
CXL14_RS06275	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CXL14_RS06295	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CXL14_RS06300	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CXL14_RS06305	COG1516	flagellar protein fliS
CXL14_RS06320	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CXL14_RS06335	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CXL14_RS06340	COG2010	Cytochrome c
CXL14_RS06345	COG2884	Cell division ATP-binding protein ftsE
CXL14_RS06350	COG2177	Part of the ABC transporter FtsEX involved in
CXL14_RS06355	COG3420	alginic acid biosynthetic process
CXL14_RS06360	COG3409	Peptidoglycan-binding domain 1 protein
CXL14_RS06360	COG0793	Belongs to the peptidase S41A family
CXL14_RS06370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CXL14_RS06385	COG1028	Short-chain dehydrogenase reductase Sdr
CXL14_RS06420	COG2814	Major facilitator Superfamily
CXL14_RS06425	COG1309	transcriptional regulator
CXL14_RS06430	COG3848	Pyruvate phosphate dikinase
CXL14_RS06430	COG0574	Belongs to the PEP-utilizing enzyme family
CXL14_RS06435	COG4897	Protein conserved in bacteria
CXL14_RS06445	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CXL14_RS06460	COG3595	metallopeptidase activity
CXL14_RS06465	COG1983	PspC domain protein
CXL14_RS06470	COG1950	PFAM Membrane protein of
CXL14_RS06475	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CXL14_RS06480	COG1309	transcriptional regulator
CXL14_RS06485	COG2188	Transcriptional regulator
CXL14_RS06495	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CXL14_RS06515	COG0110	maltose O-acetyltransferase activity
CXL14_RS06520	COG4990	cell redox homeostasis
CXL14_RS06535	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CXL14_RS06560	COG0140	phosphoribosyl-ATP diphosphatase activity
CXL14_RS06560	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CXL14_RS06565	COG1132	(ABC) transporter
CXL14_RS06575	COG0745	RESPONSE REGULATOR receiver
CXL14_RS06580	COG5002	protein histidine kinase activity
CXL14_RS06585	COG0457	Tetratricopeptide repeat
CXL14_RS06590	COG3883	PFAM NLP P60 protein
CXL14_RS06590	COG0791	NLP P60 protein
CXL14_RS06595	COG0492	ferredoxin-NADP+ reductase activity
CXL14_RS06600	COG1051	belongs to the nudix hydrolase family
CXL14_RS06610	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CXL14_RS06620	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXL14_RS06625	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CXL14_RS06630	COG4290	ribonuclease
CXL14_RS06635	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CXL14_RS06645	COG0288	reversible hydration of carbon dioxide
CXL14_RS06650	COG0659	secondary active sulfate transmembrane transporter activity
CXL14_RS06655	COG1694	Mazg nucleotide pyrophosphohydrolase
CXL14_RS06660	COG1611	Belongs to the LOG family
CXL14_RS06665	COG1609	Transcriptional regulator
CXL14_RS06670	COG0366	Alpha amylase catalytic
CXL14_RS06675	COG2182	Extracellular solute-binding protein
CXL14_RS06680	COG1175	transmembrane transport
CXL14_RS06685	COG3833	ABC-type maltose transport systems, permease component
CXL14_RS06690	COG5521	maltodextrose utilization protein MalA
CXL14_RS06695	COG1554	hydrolase, family 65, central catalytic
CXL14_RS06700	COG0366	Alpha amylase catalytic
CXL14_RS06705	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CXL14_RS06715	COG1609	Transcriptional regulator
CXL14_RS06720	COG2223	nitrite transmembrane transporter activity
CXL14_RS06775	COG3479	Phenolic acid decarboxylase
CXL14_RS06780	COG0456	acetyltransferase
CXL14_RS06785	COG2364	Membrane
CXL14_RS06790	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CXL14_RS06800	COG2272	Belongs to the type-B carboxylesterase lipase family
CXL14_RS06805	COG1396	sequence-specific DNA binding
CXL14_RS06810	COG3944	biosynthesis protein
CXL14_RS06815	COG0489	protein tyrosine kinase activity
CXL14_RS06820	COG1086	Polysaccharide biosynthesis protein
CXL14_RS06825	COG0438	transferase activity, transferring glycosyl groups
CXL14_RS06830	COG1215	transferase activity, transferring glycosyl groups
CXL14_RS06835	COG0438	transferase activity, transferring glycosyl groups
CXL14_RS06845	COG1216	Glycosyl transferase, family 2
CXL14_RS06850	COG5039	Polysaccharide pyruvyl transferase
CXL14_RS06855	COG1216	Glycosyl transferase, family 2
CXL14_RS06860	COG2244	polysaccharide biosynthetic process
CXL14_RS06865	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CXL14_RS06870	COG0110	maltose O-acetyltransferase activity
CXL14_RS06875	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CXL14_RS06880	COG5039	Polysaccharide pyruvyl transferase
CXL14_RS06890	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CXL14_RS06895	COG1620	l-lactate permease
CXL14_RS06900	COG2186	Transcriptional regulator
CXL14_RS06905	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CXL14_RS06940	COG1070	Carbohydrate kinase
CXL14_RS06945	COG1737	Transcriptional regulator
CXL14_RS06950	COG1113	amino acid transport
CXL14_RS06955	COG0697	spore germination
CXL14_RS06960	COG0583	DNA-binding transcription factor activity
CXL14_RS06965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CXL14_RS06970	COG1609	Transcriptional regulator
CXL14_RS06975	COG2814	Major facilitator Superfamily
CXL14_RS06980	COG2390	Transcriptional regulator
CXL14_RS06985	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CXL14_RS06995	COG0126	phosphoglycerate kinase activity
CXL14_RS07015	COG0456	acetyltransferase
CXL14_RS07020	COG4640	response to antibiotic
CXL14_RS07025	COG3064	Membrane
CXL14_RS07030	COG2095	MarC family integral membrane protein
CXL14_RS07035	COG1510	regulation of RNA biosynthetic process
CXL14_RS07040	COG1125	glycine betaine transport
CXL14_RS07040	COG0517	IMP dehydrogenase activity
CXL14_RS07045	COG1174	glycine betaine transport
CXL14_RS07050	COG1732	Glycine betaine
CXL14_RS07055	COG1174	glycine betaine transport
CXL14_RS07060	COG1510	regulation of RNA biosynthetic process
CXL14_RS07065	COG0517	IMP dehydrogenase activity
CXL14_RS07065	COG1125	glycine betaine transport
CXL14_RS07070	COG1174	glycine betaine transport
CXL14_RS07075	COG1732	Glycine betaine
CXL14_RS07080	COG1174	glycine betaine transport
CXL14_RS07085	COG1131	(ABC) transporter
CXL14_RS07110	COG1733	regulation of RNA biosynthetic process
CXL14_RS07115	COG1396	sequence-specific DNA binding
CXL14_RS07120	COG1396	sequence-specific DNA binding
CXL14_RS07125	COG1476	TRANSCRIPTIONal
CXL14_RS07130	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CXL14_RS07135	COG1647	Serine aminopeptidase, S33
CXL14_RS07140	COG0557	exoribonuclease II activity
CXL14_RS07155	COG2732	(Barnase) inhibitor
CXL14_RS07165	COG2732	(Barnase) inhibitor
CXL14_RS07170	COG1028	Short-chain dehydrogenase reductase Sdr
CXL14_RS07175	COG0583	DNA-binding transcription factor activity
CXL14_RS07180	COG0454	-acetyltransferase
CXL14_RS07185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXL14_RS07190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXL14_RS07195	COG0765	amino acid transport
CXL14_RS07200	COG0765	amino acid transport
CXL14_RS07205	COG1126	abc transporter atp-binding protein
CXL14_RS07210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CXL14_RS07215	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CXL14_RS07220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CXL14_RS07230	COG0673	inositol 2-dehydrogenase activity
CXL14_RS07235	COG1937	Protein conserved in bacteria
CXL14_RS07240	COG2608	mercury ion transmembrane transporter activity
CXL14_RS07245	COG2217	Heavy metal translocating P-type atpase
CXL14_RS07250	COG2217	Heavy metal translocating P-type atpase
CXL14_RS07255	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CXL14_RS07260	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CXL14_RS07270	COG2860	membrane
CXL14_RS07275	COG3973	AAA domain
CXL14_RS07280	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CXL14_RS07305	COG0656	L-ascorbic acid biosynthetic process
CXL14_RS07310	COG0842	Transport permease protein
CXL14_RS07320	COG1131	(ABC) transporter
CXL14_RS07325	COG3850	Histidine kinase
CXL14_RS07330	COG2197	response regulator
CXL14_RS07335	COG4149	molybdate abc transporter
CXL14_RS07340	COG0725	ABC transporter, periplasmic molybdate-binding protein
CXL14_RS07345	COG1910	domain protein
CXL14_RS07350	COG1368	sulfuric ester hydrolase activity
CXL14_RS07355	COG1988	membrane-bound metal-dependent
CXL14_RS07370	COG0531	amino acid
CXL14_RS07375	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CXL14_RS07380	COG1309	transcriptional regulator
CXL14_RS07400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CXL14_RS07410	COG3118	belongs to the thioredoxin family
CXL14_RS07415	COG0492	ferredoxin-NADP+ reductase activity
CXL14_RS07435	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CXL14_RS07440	COG0509	glycine decarboxylation via glycine cleavage system
CXL14_RS07445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CXL14_RS07475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CXL14_RS07480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CXL14_RS07485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CXL14_RS07490	COG1120	ATPase activity
CXL14_RS07500	COG2140	Oxalate decarboxylase
CXL14_RS07510	COG1191	sigma factor activity
CXL14_RS07520	COG0745	RESPONSE REGULATOR receiver
CXL14_RS07525	COG2205	protein histidine kinase activity
CXL14_RS07530	COG3386	PFAM SMP-30 Gluconolaconase
CXL14_RS07535	COG1028	Short-chain dehydrogenase reductase Sdr
CXL14_RS07540	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CXL14_RS07545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CXL14_RS07550	COG1120	ATPase activity
CXL14_RS07555	COG2096	Adenosyltransferase
CXL14_RS07560	COG2814	Major facilitator Superfamily
CXL14_RS07565	COG4758	membrane
CXL14_RS07570	COG1842	Phage shock protein A
CXL14_RS07575	COG3595	metallopeptidase activity
CXL14_RS07580	COG4758	membrane
CXL14_RS07585	COG4585	Histidine kinase
CXL14_RS07590	COG2197	response regulator
CXL14_RS07600	COG0814	amino acid
CXL14_RS07605	COG0697	spore germination
CXL14_RS07615	COG0114	fumarate hydratase activity
CXL14_RS07620	COG1309	transcriptional regulator
CXL14_RS07630	COG2205	protein histidine kinase activity
CXL14_RS07630	COG2770	Histidine kinase
CXL14_RS07635	COG0745	RESPONSE REGULATOR receiver
CXL14_RS07640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CXL14_RS07645	COG0783	Belongs to the Dps family
CXL14_RS07650	COG1028	Short-chain dehydrogenase reductase Sdr
CXL14_RS07665	COG1120	ATPase activity
CXL14_RS07685	COG0583	DNA-binding transcription factor activity
CXL14_RS07690	COG0477	Major facilitator Superfamily
CXL14_RS07695	COG1846	Transcriptional regulator
CXL14_RS07700	COG5577	PFAM Coat F domain
CXL14_RS07720	COG1024	Enoyl-CoA hydratase
CXL14_RS07720	COG1250	3-hydroxyacyl-CoA dehydrogenase
CXL14_RS07725	COG0183	Belongs to the thiolase family
CXL14_RS07730	COG1960	acyl-CoA dehydrogenase activity
CXL14_RS07735	COG1393	Belongs to the ArsC family
CXL14_RS07750	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CXL14_RS07755	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CXL14_RS07765	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CXL14_RS07770	COG2011	ABC-type metal ion transport system permease component
CXL14_RS07775	COG1464	Belongs to the NlpA lipoprotein family
CXL14_RS07780	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CXL14_RS07790	COG0396	ATPase activity
CXL14_RS07795	COG0719	Fe-S assembly protein
CXL14_RS07800	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CXL14_RS07805	COG0822	iron-sulfur transferase activity
CXL14_RS07810	COG0719	Fe-S assembly protein
CXL14_RS07815	COG3409	Peptidoglycan-binding domain 1 protein
CXL14_RS07835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CXL14_RS07840	COG0322	excinuclease ABC activity
CXL14_RS07865	COG0789	Transcriptional regulator
CXL14_RS07870	COG2222	sugar isomerase
CXL14_RS07875	COG1653	transport
CXL14_RS07880	COG1175	transmembrane transport
CXL14_RS07885	COG0395	ABC-type sugar transport system, permease component
CXL14_RS07890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXL14_RS07895	COG2188	Transcriptional regulator
CXL14_RS07900	COG3842	ATPase activity
CXL14_RS07905	COG2356	endonuclease I
CXL14_RS07910	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CXL14_RS07915	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CXL14_RS07920	COG2814	Major facilitator Superfamily
CXL14_RS07935	COG0457	Tetratricopeptide repeat
CXL14_RS07940	COG2508	Transcriptional regulator
CXL14_RS07955	COG1801	Protein of unknown function DUF72
CXL14_RS07960	COG0730	response to heat
CXL14_RS07965	COG0737	Belongs to the 5'-nucleotidase family
CXL14_RS07975	COG0739	heme binding
CXL14_RS07990	COG4470	Protein conserved in bacteria
CXL14_RS07995	COG2445	Protein of unknown function DUF86
CXL14_RS08000	COG0647	UMP catabolic process
CXL14_RS08005	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CXL14_RS08010	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CXL14_RS08015	COG0460	homoserine dehydrogenase
CXL14_RS08020	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CXL14_RS08030	COG0823	Involved in the tonB-independent uptake of proteins
CXL14_RS08030	COG4946	Tricorn protease homolog
CXL14_RS08030	COG1506	peptidase
CXL14_RS08035	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CXL14_RS08040	COG4837	Protein of unknown function (DUF1462)
CXL14_RS08045	COG1252	NADH dehydrogenase
CXL14_RS08055	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CXL14_RS08065	COG0316	Belongs to the HesB IscA family
CXL14_RS08070	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CXL14_RS08075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CXL14_RS08095	COG1131	(ABC) transporter
CXL14_RS08125	COG1252	NADH dehydrogenase
CXL14_RS08140	COG3584	3D domain protein
CXL14_RS08145	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
CXL14_RS08155	COG2056	Na+-H+ antiporter family
CXL14_RS08160	COG1268	BioY protein
CXL14_RS08165	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CXL14_RS08170	COG2819	hydrolase of the alpha beta superfamily
CXL14_RS08175	COG1028	Short-chain dehydrogenase reductase Sdr
CXL14_RS08180	COG1169	isochorismate synthase
CXL14_RS08185	COG1021	2,3-dihydroxybenzoate-AMP ligase
CXL14_RS08190	COG1535	isochorismatase
CXL14_RS08190	COG3433	isochorismatase activity
CXL14_RS08195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXL14_RS08200	COG3251	PFAM MbtH domain protein
CXL14_RS08205	COG5634	Uncharacterized conserved protein (DUF2278)
CXL14_RS08210	COG0686	Belongs to the AlaDH PNT family
CXL14_RS08215	COG2508	Transcriptional regulator
CXL14_RS08215	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CXL14_RS08220	COG4842	Belongs to the WXG100 family
CXL14_RS08225	COG5417	Belongs to the EsaB family
CXL14_RS08230	COG4499	WXG100 protein secretion system (Wss), protein YukC
CXL14_RS08235	COG1674	ftsk spoiiie
CXL14_RS08235	COG0433	COG0433 Predicted ATPase
CXL14_RS08240	COG1511	domain protein
CXL14_RS08250	COG1028	Short-chain dehydrogenase reductase Sdr
CXL14_RS08255	COG1418	mRNA catabolic process
CXL14_RS08265	COG0628	permease
CXL14_RS08280	COG5506	Protein of unknown function (DUF1694)
CXL14_RS08285	COG1335	isochorismatase
CXL14_RS08290	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CXL14_RS08295	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CXL14_RS08315	COG0142	geranyltranstransferase activity
CXL14_RS08325	COG4585	Histidine kinase
CXL14_RS08330	COG2197	response regulator
CXL14_RS08335	COG2050	protein possibly involved in aromatic compounds catabolism
CXL14_RS08340	COG1320	monovalent cation:proton antiporter activity
CXL14_RS08345	COG2212	antiporter activity
CXL14_RS08350	COG1863	multisubunit Na H antiporter MnhE subunit
CXL14_RS08355	COG0651	ATP synthesis coupled electron transport
CXL14_RS08360	COG1006	Multisubunit Na H antiporter MnhC subunit
CXL14_RS08365	COG2111	Na H antiporter
CXL14_RS08370	COG2111	Na H antiporter
CXL14_RS08370	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CXL14_RS08380	COG1079	Belongs to the binding-protein-dependent transport system permease family
CXL14_RS08385	COG4603	Belongs to the binding-protein-dependent transport system permease family
CXL14_RS08390	COG3845	ABC transporter
CXL14_RS08395	COG1744	ABC transporter substrate-binding protein PnrA-like
CXL14_RS08400	COG4565	transcriptional regulatory protein
CXL14_RS08405	COG3290	protein histidine kinase activity
CXL14_RS08415	COG3011	Protein conserved in bacteria
CXL14_RS08420	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CXL14_RS08425	COG2814	Major facilitator Superfamily
CXL14_RS08430	COG5018	Exonuclease
CXL14_RS08440	COG2205	protein histidine kinase activity
CXL14_RS08445	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CXL14_RS08455	COG2267	carboxylic ester hydrolase activity
CXL14_RS08460	COG1522	sequence-specific DNA binding
CXL14_RS08465	COG0436	Aminotransferase
CXL14_RS08470	COG1098	S1 RNA binding domain
CXL14_RS08475	COG2155	Conserved Protein
CXL14_RS08480	COG1979	alcohol dehydrogenase
CXL14_RS08485	COG1979	alcohol dehydrogenase
CXL14_RS08490	COG1335	isochorismatase
CXL14_RS08520	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CXL14_RS08535	COG2738	Putative neutral zinc metallopeptidase
CXL14_RS08540	COG1253	flavin adenine dinucleotide binding
CXL14_RS08545	COG0366	Alpha amylase catalytic
CXL14_RS08550	COG0432	Pfam Uncharacterised protein family UPF0047
CXL14_RS08555	COG2070	2-Nitropropane dioxygenase
CXL14_RS08570	COG0840	transmembrane signaling receptor activity
CXL14_RS08575	COG0840	transmembrane signaling receptor activity
CXL14_RS08580	COG0840	transmembrane signaling receptor activity
CXL14_RS08585	COG0840	transmembrane signaling receptor activity
CXL14_RS08590	COG0693	protein deglycase activity
CXL14_RS08595	COG0673	inositol 2-dehydrogenase activity
CXL14_RS08600	COG0628	permease
CXL14_RS08625	COG1017	nitric oxide dioxygenase activity
CXL14_RS08625	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CXL14_RS08630	COG1705	Flagellar rod assembly protein muramidase FlgJ
CXL14_RS08635	COG0569	domain protein
CXL14_RS08645	COG1510	regulation of RNA biosynthetic process
CXL14_RS08650	COG1012	belongs to the aldehyde dehydrogenase family
CXL14_RS08655	COG1454	alcohol dehydrogenase
CXL14_RS08665	COG2318	DinB family
CXL14_RS08670	COG1585	Membrane protein implicated in regulation of membrane protease activity
CXL14_RS08675	COG2268	Band 7 protein
CXL14_RS08680	COG3859	Proton-coupled thiamine transporter YuaJ
CXL14_RS08805	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CXL14_RS08810	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CXL14_RS08815	COG1169	isochorismate synthase
CXL14_RS08825	COG0596	Alpha beta hydrolase
CXL14_RS08830	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CXL14_RS08840	COG4948	Mandelate Racemase Muconate Lactonizing
CXL14_RS08845	COG0803	Belongs to the bacterial solute-binding protein 9 family
CXL14_RS08850	COG1121	(ABC) transporter
CXL14_RS08855	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CXL14_RS08855	COG1321	iron dependent repressor
CXL14_RS08860	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CXL14_RS08870	COG1294	oxidase, subunit
CXL14_RS08875	COG1271	oxidase subunit
CXL14_RS08885	COG0288	reversible hydration of carbon dioxide
CXL14_RS08910	COG0783	Belongs to the Dps family
CXL14_RS08915	COG4824	toxin secretion phage lysis holin
CXL14_RS08920	COG0494	nUDIX hydrolase
CXL14_RS08925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CXL14_RS08930	COG1116	anion transmembrane transporter activity
CXL14_RS08935	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CXL14_RS08940	COG1506	peptidase
CXL14_RS08960	COG0367	asparagine synthase
CXL14_RS08965	COG1113	amino acid transport
CXL14_RS08970	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CXL14_RS08975	COG2267	carboxylic ester hydrolase activity
CXL14_RS08985	COG0584	glycerophosphoryl diester phosphodiesterase
CXL14_RS08995	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CXL14_RS09000	COG1242	4 iron, 4 sulfur cluster binding
CXL14_RS09010	COG1725	Transcriptional regulator
CXL14_RS09015	COG1131	(ABC) transporter
CXL14_RS09035	COG1136	(ABC) transporter
CXL14_RS09040	COG0577	efflux transmembrane transporter activity
CXL14_RS09045	COG0745	RESPONSE REGULATOR receiver
CXL14_RS09050	COG2205	protein histidine kinase activity
CXL14_RS09055	COG1136	(ABC) transporter
CXL14_RS09060	COG0577	efflux transmembrane transporter activity
CXL14_RS09065	COG5522	Integral membrane protein (intg_mem_TP0381)
CXL14_RS09070	COG2814	Major facilitator Superfamily
CXL14_RS09075	COG1366	Belongs to the anti-sigma-factor antagonist family
CXL14_RS09075	COG2202	Pas domain
CXL14_RS09090	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CXL14_RS09100	COG1486	melibiose metabolic process
CXL14_RS09105	COG0395	ABC-type sugar transport system, permease component
CXL14_RS09110	COG1175	transmembrane transport
CXL14_RS09115	COG1653	transport
CXL14_RS09120	COG1609	Transcriptional regulator
CXL14_RS09130	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CXL14_RS09135	COG2081	HI0933 family
CXL14_RS09140	COG2244	polysaccharide biosynthetic process
CXL14_RS09145	COG1187	pseudouridine synthase activity
CXL14_RS09150	COG1349	DNA-binding transcription factor activity
CXL14_RS09155	COG1131	(ABC) transporter
CXL14_RS09160	COG4473	ABC transporter
CXL14_RS09165	COG2252	PERMEase
CXL14_RS09170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CXL14_RS09175	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CXL14_RS09180	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CXL14_RS09190	COG1597	lipid kinase activity
CXL14_RS09195	COG0510	thiamine kinase activity
CXL14_RS09210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CXL14_RS09215	COG0281	malic enzyme
CXL14_RS09220	COG5584	Small secreted protein
CXL14_RS09225	COG1363	Peptidase, m42
CXL14_RS09245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CXL14_RS09255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CXL14_RS09260	COG1674	ftsk spoiiie
CXL14_RS09270	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CXL14_RS09275	COG4980	gas vesicle protein
CXL14_RS09280	COG3118	belongs to the thioredoxin family
CXL14_RS09285	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CXL14_RS09285	COG1605	Chorismate mutase
CXL14_RS09290	COG1609	Transcriptional regulator
CXL14_RS09295	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CXL14_RS09300	COG1360	Flagellar Motor Protein
CXL14_RS09305	COG0123	including yeast histone deacetylase and acetoin utilization protein
CXL14_RS09310	COG0517	IMP dehydrogenase activity
CXL14_RS09315	COG0454	-acetyltransferase
CXL14_RS09320	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CXL14_RS09345	COG1378	Sugar-specific transcriptional regulator TrmB
CXL14_RS09350	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CXL14_RS09365	COG0693	protein deglycase activity
CXL14_RS09375	COG1017	nitric oxide dioxygenase activity
CXL14_RS09375	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CXL14_RS09425	COG4282	regulation of fungal-type cell wall biogenesis
CXL14_RS09430	COG1012	belongs to the aldehyde dehydrogenase family
CXL14_RS09445	COG2203	Gaf domain
CXL14_RS09445	COG2199	diguanylate cyclase activity
CXL14_RS09450	COG1956	GAF domain-containing protein
CXL14_RS09455	COG1309	transcriptional regulator
CXL14_RS09460	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CXL14_RS09470	COG1114	Component of the transport system for branched-chain amino acids
CXL14_RS09475	COG1104	cysteine desulfurase activity
CXL14_RS09490	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CXL14_RS09495	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CXL14_RS09500	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CXL14_RS09505	COG0616	signal peptide processing
CXL14_RS09510	COG1714	RDD family
CXL14_RS09520	COG3874	Sporulation protein YtfJ
CXL14_RS09525	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CXL14_RS09530	COG0827	DNA restriction-modification system
CXL14_RS09540	COG0521	Mo-molybdopterin cofactor biosynthetic process
CXL14_RS09555	COG1028	Short-chain dehydrogenase reductase Sdr
CXL14_RS09565	COG4109	DRTGG domain
CXL14_RS09575	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CXL14_RS09595	COG0587	DNA-directed DNA polymerase activity
CXL14_RS09600	COG0281	malic enzyme
CXL14_RS09620	COG0469	pyruvate kinase activity
CXL14_RS09625	COG3030	protein affecting phage T7 exclusion by the F plasmid
CXL14_RS09630	COG0628	permease
CXL14_RS09660	COG0457	Tetratricopeptide repeat
CXL14_RS09665	COG0372	Belongs to the citrate synthase family
CXL14_RS09670	COG0538	isocitrate dehydrogenase activity
CXL14_RS09680	COG0745	RESPONSE REGULATOR receiver
CXL14_RS09685	COG5002	protein histidine kinase activity
CXL14_RS09690	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CXL14_RS09690	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CXL14_RS09695	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CXL14_RS09700	COG1971	Probably functions as a manganese efflux pump
CXL14_RS09705	COG0237	dephospho-CoA kinase activity
CXL14_RS09710	COG0656	L-ascorbic acid biosynthetic process
CXL14_RS09715	COG2814	Major facilitator Superfamily
CXL14_RS09720	COG1733	regulation of RNA biosynthetic process
CXL14_RS09725	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CXL14_RS09740	COG3611	Membrane attachment protein
CXL14_RS09745	COG1484	DNA-dependent DNA replication
CXL14_RS09750	COG0398	Pfam SNARE associated Golgi protein
CXL14_RS09765	COG1011	Hydrolase
CXL14_RS09770	COG3275	phosphorelay sensor kinase activity
CXL14_RS09775	COG3279	Response regulator of the LytR AlgR family
CXL14_RS09780	COG1380	Effector of murein hydrolase LrgA
CXL14_RS09785	COG1346	cytolysis
CXL14_RS09790	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CXL14_RS09805	COG3326	Membrane
CXL14_RS09815	COG1363	Peptidase, m42
CXL14_RS09820	COG3507	Belongs to the glycosyl hydrolase 43 family
CXL14_RS09825	COG2160	L-arabinose isomerase activity
CXL14_RS09830	COG1069	ribulokinase activity
CXL14_RS09835	COG0235	Class ii aldolase
CXL14_RS09840	COG0647	UMP catabolic process
CXL14_RS09850	COG1653	transport
CXL14_RS09855	COG1175	transmembrane transport
CXL14_RS09860	COG0395	ABC-type sugar transport system, permease component
CXL14_RS09865	COG3534	alpha-L-arabinofuranosidase
CXL14_RS09870	COG1966	Carbon starvation protein
CXL14_RS09875	COG0247	lactate metabolic process
CXL14_RS09880	COG0277	FAD linked oxidase domain protein
CXL14_RS09885	COG3835	regulator
CXL14_RS09895	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CXL14_RS09900	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CXL14_RS09905	COG0072	phenylalanine-tRNA ligase activity
CXL14_RS09905	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CXL14_RS09920	COG1286	toxin biosynthetic process
CXL14_RS09925	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CXL14_RS09925	COG1796	DNA polymerase
CXL14_RS09935	COG3766	membrane
CXL14_RS09945	COG0318	PFAM AMP-dependent synthetase and ligase
CXL14_RS09950	COG1309	transcriptional regulator
CXL14_RS09955	COG1024	Enoyl-CoA hydratase
CXL14_RS09960	COG2086	electron transfer activity
CXL14_RS09965	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CXL14_RS09970	COG3534	alpha-L-arabinofuranosidase
CXL14_RS09975	COG3118	belongs to the thioredoxin family
CXL14_RS09990	COG0527	aspartate kinase activity
CXL14_RS09995	COG1719	4-vinyl reductase, 4VR
CXL14_RS10000	COG2009	succinate dehydrogenase
CXL14_RS10005	COG1053	succinate dehydrogenase
CXL14_RS10010	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CXL14_RS10015	COG0824	Thioesterase
CXL14_RS10020	COG2197	response regulator
CXL14_RS10025	COG1846	Transcriptional regulator
CXL14_RS10035	COG5401	PFAM Sporulation and spore germination
CXL14_RS10045	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CXL14_RS10050	COG0622	Phosphoesterase
CXL14_RS10075	COG0028	Belongs to the TPP enzyme family
CXL14_RS10080	COG0440	acetolactate synthase activity
CXL14_RS10095	COG0473	3-isopropylmalate dehydrogenase activity
CXL14_RS10110	COG0457	Tetratricopeptide repeat
CXL14_RS10110	COG1477	protein flavinylation
CXL14_RS10125	COG0470	DNA polymerase III
CXL14_RS10125	COG1067	ATP-dependent peptidase activity
CXL14_RS10130	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CXL14_RS10150	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CXL14_RS10160	COG1587	Uroporphyrinogen-III synthase
CXL14_RS10165	COG0113	porphobilinogen synthase activity
CXL14_RS10175	COG1388	LysM domain
CXL14_RS10180	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CXL14_RS10190	COG0525	valine-tRNA ligase activity
CXL14_RS10195	COG0285	dihydrofolate synthase activity
CXL14_RS10200	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CXL14_RS10220	COG1077	Cell shape determining protein MreB Mrl
CXL14_RS10230	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CXL14_RS10240	COG2894	cell division
CXL14_RS10245	COG0739	heme binding
CXL14_RS10250	COG1994	Peptidase M50
CXL14_RS10260	COG2868	ribosomal protein
CXL14_RS10265	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CXL14_RS10270	COG3290	protein histidine kinase activity
CXL14_RS10285	COG0077	Prephenate dehydratase
CXL14_RS10290	COG1827	regulation of RNA biosynthetic process
CXL14_RS10295	COG1104	cysteine desulfurase activity
CXL14_RS10300	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CXL14_RS10305	COG0157	Belongs to the NadC ModD family
CXL14_RS10315	COG1388	LysM domain
CXL14_RS10360	COG1862	Preprotein translocase
CXL14_RS10370	COG2323	membrane
CXL14_RS10375	COG2244	polysaccharide biosynthetic process
CXL14_RS10385	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CXL14_RS10385	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CXL14_RS10390	COG0490	domain, Protein
CXL14_RS10395	COG5416	Lipopolysaccharide assembly protein A domain
CXL14_RS10400	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CXL14_RS10400	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CXL14_RS10410	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CXL14_RS10420	COG3103	Sh3 type 3 domain protein
CXL14_RS10420	COG0860	N-Acetylmuramoyl-L-alanine amidase
CXL14_RS10420	COG4991	sh3 domain protein
CXL14_RS10440	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CXL14_RS10445	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CXL14_RS10450	COG1959	2 iron, 2 sulfur cluster binding
CXL14_RS10455	COG1104	cysteine desulfurase activity
CXL14_RS10465	COG0457	Tetratricopeptide repeat
CXL14_RS10470	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CXL14_RS10475	COG3881	PFAM PRC-barrel domain
CXL14_RS10490	COG0765	amino acid transport
CXL14_RS10495	COG0765	amino acid transport
CXL14_RS10500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXL14_RS10505	COG1126	abc transporter atp-binding protein
CXL14_RS10510	COG0628	permease
CXL14_RS10520	COG4472	Bacterial protein of unknown function (DUF965)
CXL14_RS10535	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CXL14_RS10540	COG4122	O-methyltransferase activity
CXL14_RS10545	COG0826	peptidase U32
CXL14_RS10550	COG0826	peptidase U32
CXL14_RS10565	COG0768	penicillin binding
CXL14_RS10590	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CXL14_RS10595	COG0626	cystathionine gamma-synthase activity
CXL14_RS10605	COG2427	Protein of unknown function (DUF1641)
CXL14_RS10610	COG3383	formate dehydrogenase (NAD+) activity
CXL14_RS10615	COG5609	conserved protein (DUF2294)
CXL14_RS10620	COG2116	formate transmembrane transporter activity
CXL14_RS10635	COG2226	methyltransferase
CXL14_RS10640	COG1309	transcriptional regulator
CXL14_RS10645	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CXL14_RS10645	COG2124	cytochrome p450
CXL14_RS10650	COG2814	Major facilitator Superfamily
CXL14_RS10655	COG0583	DNA-binding transcription factor activity
CXL14_RS10660	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CXL14_RS10670	COG3711	transcriptional antiterminator
CXL14_RS10670	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXL14_RS10675	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXL14_RS10675	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXL14_RS10675	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXL14_RS10680	COG1482	cell wall glycoprotein biosynthetic process
CXL14_RS10690	COG0561	phosphatase activity
CXL14_RS10695	COG0561	phosphatase activity
CXL14_RS10705	COG2318	DinB family
CXL14_RS10710	COG0456	acetyltransferase
CXL14_RS10715	COG2814	Major facilitator Superfamily
CXL14_RS10725	COG0563	adenylate kinase activity
CXL14_RS10730	COG0454	-acetyltransferase
CXL14_RS10735	COG2311	Membrane
CXL14_RS10740	COG0745	RESPONSE REGULATOR receiver
CXL14_RS10745	COG5002	protein histidine kinase activity
CXL14_RS10745	COG0642	Histidine kinase
CXL14_RS10760	COG0583	DNA-binding transcription factor activity
CXL14_RS10765	COG2207	Transcriptional regulator
CXL14_RS10765	COG3708	Transcriptional regulator
CXL14_RS10810	COG0398	Pfam SNARE associated Golgi protein
CXL14_RS10820	COG2755	lipolytic protein G-D-S-L family
CXL14_RS10830	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CXL14_RS10835	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CXL14_RS10840	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CXL14_RS10845	COG1534	Rna-binding protein
CXL14_RS10855	COG1713	HD superfamily hydrolase involved in NAD metabolism
CXL14_RS10860	COG0799	negative regulation of ribosome biogenesis
CXL14_RS10865	COG2226	methyltransferase
CXL14_RS10870	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CXL14_RS10875	COG1596	polysaccharide export
CXL14_RS10875	COG1555	photosystem II stabilization
CXL14_RS10880	COG2131	deaminase
CXL14_RS10885	COG2333	competence protein COMEC
CXL14_RS10885	COG0658	competence protein
CXL14_RS10895	COG1466	dna polymerase III delta subunit
CXL14_RS10910	COG0860	N-Acetylmuramoyl-L-alanine amidase
CXL14_RS10925	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CXL14_RS10955	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CXL14_RS10960	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CXL14_RS10965	COG1283	sodium-dependent phosphate transmembrane transporter activity
CXL14_RS10975	COG1610	YqeY-like protein
CXL14_RS10980	COG1030	water channel activity
CXL14_RS10985	COG4864	UPF0365 protein
CXL14_RS11000	COG0561	phosphatase activity
CXL14_RS11005	COG1702	phosphate starvation-inducible protein PhoH
CXL14_RS11010	COG1480	7TM receptor with intracellular HD hydrolase
CXL14_RS11020	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CXL14_RS11025	COG0295	cytidine deaminase activity
CXL14_RS11030	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CXL14_RS11050	COG0751	glycine-tRNA ligase activity
CXL14_RS11055	COG0517	IMP dehydrogenase activity
CXL14_RS11070	COG0358	DNA primase activity
CXL14_RS11075	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CXL14_RS11080	COG2010	Cytochrome c
CXL14_RS11085	COG2384	SAM-dependent methyltransferase
CXL14_RS11090	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CXL14_RS11105	COG0513	Belongs to the DEAD box helicase family
CXL14_RS11120	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CXL14_RS11125	COG0735	belongs to the Fur family
CXL14_RS11130	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
CXL14_RS11135	COG4709	membrane
CXL14_RS11145	COG1388	LysM domain
CXL14_RS11150	COG5521	maltodextrose utilization protein MalA
CXL14_RS11155	COG2839	Protein conserved in bacteria
CXL14_RS11160	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CXL14_RS11165	COG0477	Major facilitator Superfamily
CXL14_RS11170	COG0768	penicillin binding
CXL14_RS11175	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CXL14_RS11180	COG0573	inorganic phosphate transmembrane transporter activity
CXL14_RS11185	COG0581	inorganic phosphate transmembrane transporter activity
CXL14_RS11190	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CXL14_RS11195	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CXL14_RS11200	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CXL14_RS11215	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CXL14_RS11225	COG1757	Na H antiporter
CXL14_RS11230	COG4483	Protein conserved in bacteria
CXL14_RS11235	COG1940	carbohydrate kinase activity
CXL14_RS11240	COG2866	Carboxypeptidase
CXL14_RS11250	COG0011	TIGRFAM Protein of
CXL14_RS11260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CXL14_RS11270	COG1393	Belongs to the ArsC family
CXL14_RS11280	COG1366	Belongs to the anti-sigma-factor antagonist family
CXL14_RS11285	COG1253	flavin adenine dinucleotide binding
CXL14_RS11290	COG0598	Magnesium transport protein CorA
CXL14_RS11295	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CXL14_RS11300	COG1459	type II secretion system
CXL14_RS11305	COG4537	Required for transformation and DNA binding
CXL14_RS11310	COG4970	Tfp pilus assembly protein FimT
CXL14_RS11320	COG4940	Competence protein ComGF
CXL14_RS11345	COG0681	Belongs to the peptidase S26 family
CXL14_RS11355	COG1396	sequence-specific DNA binding
CXL14_RS11370	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CXL14_RS11390	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CXL14_RS11405	COG1752	Esterase of the alpha-beta hydrolase superfamily
CXL14_RS11415	COG3872	metal-dependent enzyme
CXL14_RS11425	COG0006	proline dipeptidase activity
CXL14_RS11440	COG3854	ATPases associated with a variety of cellular activities
CXL14_RS11480	COG0511	ligase activity, forming carbon-carbon bonds
CXL14_RS11485	COG0439	Biotin carboxylase
CXL14_RS11490	COG1302	Protein conserved in bacteria
CXL14_RS11505	COG1570	exodeoxyribonuclease VII activity
CXL14_RS11515	COG0142	geranyltranstransferase activity
CXL14_RS11525	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CXL14_RS11535	COG0497	DNA recombination
CXL14_RS11540	COG0750	zinc metalloprotease
CXL14_RS11545	COG0745	RESPONSE REGULATOR receiver
CXL14_RS11550	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CXL14_RS11565	COG1902	pentaerythritol trinitrate reductase activity
CXL14_RS11585	COG0860	N-Acetylmuramoyl-L-alanine amidase
CXL14_RS11590	COG0584	glycerophosphoryl diester phosphodiesterase
CXL14_RS11595	COG0183	Belongs to the thiolase family
CXL14_RS11600	COG1250	3-hydroxyacyl-CoA dehydrogenase
CXL14_RS11605	COG1960	acyl-CoA dehydrogenase activity
CXL14_RS11610	COG0372	Belongs to the citrate synthase family
CXL14_RS11615	COG2079	MmgE PrpD family protein
CXL14_RS11620	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CXL14_RS11630	COG3829	transcription factor binding
CXL14_RS11630	COG3290	protein histidine kinase activity
CXL14_RS11635	COG0280	phosphate acetyltransferase
CXL14_RS11640	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CXL14_RS11645	COG3426	butyrate kinase activity
CXL14_RS11650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CXL14_RS11655	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CXL14_RS11660	COG0022	dehydrogenase e1 component
CXL14_RS11665	COG0508	dehydrogenase complex catalyzes the overall conversion of
CXL14_RS11670	COG1597	lipid kinase activity
CXL14_RS11680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXL14_RS11685	COG0765	amino acid transport
CXL14_RS11690	COG1126	abc transporter atp-binding protein
CXL14_RS11695	COG4129	membrane
CXL14_RS11700	COG1376	ErfK ybiS ycfS ynhG family protein
CXL14_RS11705	COG0346	lactoylglutathione lyase activity
CXL14_RS11710	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CXL14_RS11715	COG2195	Cleaves the N-terminal amino acid of tripeptides
CXL14_RS11720	COG0706	membrane insertase activity
CXL14_RS11735	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CXL14_RS11740	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CXL14_RS11755	COG0596	Alpha beta hydrolase
CXL14_RS11780	COG0250	Participates in transcription elongation, termination and antitermination
CXL14_RS11785	COG2070	2-Nitropropane dioxygenase
CXL14_RS11785	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CXL14_RS11800	COG0318	PFAM AMP-dependent synthetase and ligase
CXL14_RS11805	COG1028	Short-chain dehydrogenase reductase Sdr
CXL14_RS11810	COG3321	synthase
CXL14_RS11810	COG1028	Short-chain dehydrogenase reductase Sdr
CXL14_RS11810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXL14_RS11810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CXL14_RS11810	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CXL14_RS11815	COG3321	synthase
CXL14_RS11815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXL14_RS11815	COG1028	Short-chain dehydrogenase reductase Sdr
CXL14_RS11815	COG0318	PFAM AMP-dependent synthetase and ligase
CXL14_RS11815	COG0300	oxidoreductase activity
CXL14_RS11820	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CXL14_RS11820	COG1028	Short-chain dehydrogenase reductase Sdr
CXL14_RS11820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXL14_RS11820	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CXL14_RS11820	COG3321	synthase
CXL14_RS11825	COG0300	oxidoreductase activity
CXL14_RS11825	COG0318	PFAM AMP-dependent synthetase and ligase
CXL14_RS11825	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXL14_RS11825	COG3321	synthase
CXL14_RS11825	COG1028	Short-chain dehydrogenase reductase Sdr
CXL14_RS11830	COG0318	PFAM AMP-dependent synthetase and ligase
CXL14_RS11830	COG3321	synthase
CXL14_RS11830	COG1028	Short-chain dehydrogenase reductase Sdr
CXL14_RS11830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXL14_RS11830	COG0300	oxidoreductase activity
CXL14_RS11835	COG3321	synthase
CXL14_RS11835	COG1028	Short-chain dehydrogenase reductase Sdr
CXL14_RS11835	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CXL14_RS11835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXL14_RS11835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CXL14_RS11840	COG3321	synthase
CXL14_RS11840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXL14_RS11840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CXL14_RS11840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CXL14_RS11840	COG1028	Short-chain dehydrogenase reductase Sdr
CXL14_RS11845	COG2124	cytochrome p450
CXL14_RS11850	COG3425	synthase
CXL14_RS11855	COG1024	Enoyl-CoA hydratase
CXL14_RS11860	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CXL14_RS11865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CXL14_RS11870	COG0300	oxidoreductase activity
CXL14_RS11875	COG3048	D-serine ammonia-lyase activity
CXL14_RS11885	COG0346	lactoylglutathione lyase activity
CXL14_RS11895	COG0628	permease
CXL14_RS11910	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CXL14_RS11915	COG0456	acetyltransferase
CXL14_RS11920	COG2329	Antibiotic biosynthesis monooxygenase
CXL14_RS11925	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CXL14_RS11925	COG0456	acetyltransferase
CXL14_RS11930	COG4918	Iron-sulphur cluster biosynthesis
CXL14_RS11940	COG1073	alpha beta
CXL14_RS11950	COG0667	Aldo Keto reductase
CXL14_RS11960	COG0494	nUDIX hydrolase
CXL14_RS11965	COG1379	DNA repair
CXL14_RS11970	COG1396	sequence-specific DNA binding
CXL14_RS11975	COG0252	asparaginase activity
CXL14_RS11980	COG1027	Aspartate ammonia-lyase
CXL14_RS11985	COG1757	Na H antiporter
CXL14_RS11990	COG0281	malic enzyme
CXL14_RS12005	COG1300	Membrane
CXL14_RS12010	COG0735	belongs to the Fur family
CXL14_RS12020	COG4974	Belongs to the 'phage' integrase family
CXL14_RS12025	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CXL14_RS12030	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CXL14_RS12035	COG1686	Belongs to the peptidase S11 family
CXL14_RS12040	COG1366	Belongs to the anti-sigma-factor antagonist family
CXL14_RS12050	COG1191	sigma factor activity
CXL14_RS12070	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CXL14_RS12085	COG0697	spore germination
CXL14_RS12090	COG0019	diaminopimelate decarboxylase activity
CXL14_RS12095	COG4086	secreted protein
CXL14_RS12100	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CXL14_RS12110	COG0681	Belongs to the peptidase S26 family
CXL14_RS12120	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CXL14_RS12120	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CXL14_RS12125	COG0307	riboflavin synthase, alpha
CXL14_RS12140	COG0456	acetyltransferase
CXL14_RS12150	COG1547	Domain of unknown function (DUF309)
CXL14_RS12175	COG1686	Belongs to the peptidase S11 family
CXL14_RS12180	COG2715	membrane protein required for spore maturation
CXL14_RS12185	COG0700	Nucleoside recognition
CXL14_RS12190	COG1187	pseudouridine synthase activity
CXL14_RS12195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CXL14_RS12200	COG1333	cytochrome c biogenesis protein
CXL14_RS12205	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CXL14_RS12210	COG0745	RESPONSE REGULATOR receiver
CXL14_RS12215	COG5002	protein histidine kinase activity
CXL14_RS12220	COG1595	DNA-templated transcription, initiation
CXL14_RS12230	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CXL14_RS12235	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CXL14_RS12240	COG1141	Ferredoxin
CXL14_RS12245	COG4955	Helix-turn-helix domain
CXL14_RS12250	COG0514	ATP-dependent DNA helicase (RecQ)
CXL14_RS12255	COG1266	CAAX protease self-immunity
CXL14_RS12260	COG1388	LysM domain
CXL14_RS12270	COG1408	metallophosphoesterase
CXL14_RS12275	COG4862	establishment of competence for transformation
CXL14_RS12280	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CXL14_RS12285	COG0492	ferredoxin-NADP+ reductase activity
CXL14_RS12290	COG2339	peptidase activity
CXL14_RS12295	COG3409	Peptidoglycan-binding domain 1 protein
CXL14_RS12295	COG3773	Cell wall hydrolase
CXL14_RS12300	COG2959	enzyme of heme biosynthesis
CXL14_RS12305	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CXL14_RS12315	COG0539	negative regulation of cytoplasmic translation
CXL14_RS12355	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CXL14_RS12360	COG0776	regulation of translation
CXL14_RS12375	COG0142	geranyltranstransferase activity
CXL14_RS12385	COG0142	geranyltranstransferase activity
CXL14_RS12390	COG0105	UTP biosynthetic process
CXL14_RS12395	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CXL14_RS12410	COG4401	Chorismate mutase type I
CXL14_RS12415	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CXL14_RS12450	COG0287	Prephenate dehydrogenase
CXL14_RS12460	COG0457	Tetratricopeptide repeat
CXL14_RS12475	COG0723	plastoquinol--plastocyanin reductase activity
CXL14_RS12480	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CXL14_RS12485	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CXL14_RS12485	COG2010	Cytochrome c
CXL14_RS12490	COG4347	Protein of unknown function (DUF1405)
CXL14_RS12500	COG2140	Oxalate decarboxylase
CXL14_RS12505	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CXL14_RS12510	COG1694	Mazg nucleotide pyrophosphohydrolase
CXL14_RS12525	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CXL14_RS12530	COG0438	transferase activity, transferring glycosyl groups
CXL14_RS12560	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CXL14_RS12560	COG1199	ATP-dependent helicase activity
CXL14_RS12570	COG5353	protein conserved in bacteria
CXL14_RS12575	COG0436	Aminotransferase
CXL14_RS12585	COG3935	DnaD domain protein
CXL14_RS12590	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CXL14_RS12600	COG4499	WXG100 protein secretion system (Wss), protein YukC
CXL14_RS12600	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CXL14_RS12640	COG0071	Belongs to the small heat shock protein (HSP20) family
CXL14_RS12645	COG2190	(PTS) system
CXL14_RS12650	COG1111	helicase
CXL14_RS12650	COG1205	dead DEAH box helicase
CXL14_RS12655	COG3359	exonuclease
CXL14_RS12680	COG0116	Belongs to the methyltransferase superfamily
CXL14_RS12695	COG1199	ATP-dependent helicase activity
CXL14_RS12700	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CXL14_RS12710	COG2233	PERMEase
CXL14_RS12715	COG0582	viral genome integration into host DNA
CXL14_RS12720	COG3620	sequence-specific DNA binding
CXL14_RS12735	COG3646	Phage regulatory protein
CXL14_RS12735	COG3645	SOS response
CXL14_RS12775	COG3935	DnaD domain protein
CXL14_RS12780	COG1484	DNA-dependent DNA replication
CXL14_RS12785	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CXL14_RS12810	COG1595	DNA-templated transcription, initiation
CXL14_RS12910	COG3953	SLT domain
CXL14_RS12910	COG5280	Phage tail tape measure protein TP901
CXL14_RS12920	COG1705	Flagellar rod assembly protein muramidase FlgJ
CXL14_RS12925	COG5434	Belongs to the glycosyl hydrolase 28 family
CXL14_RS12945	COG4824	toxin secretion phage lysis holin
CXL14_RS12985	COG1335	isochorismatase
CXL14_RS13010	COG3424	synthase
CXL14_RS13015	COG1755	Isoprenylcysteine carboxyl methyltransferase
CXL14_RS13025	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CXL14_RS13040	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CXL14_RS13050	COG0328	RNA-DNA hybrid ribonuclease activity
CXL14_RS13055	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CXL14_RS13060	COG0328	RNA-DNA hybrid ribonuclease activity
CXL14_RS13080	COG1278	Cold shock
CXL14_RS13085	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CXL14_RS13095	COG0386	Belongs to the glutathione peroxidase family
CXL14_RS13100	COG1418	mRNA catabolic process
CXL14_RS13105	COG1413	lyase activity
CXL14_RS13120	COG2521	methyltransferase
CXL14_RS13120	COG2136	Putative SAM-dependent methyltransferase
CXL14_RS13135	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CXL14_RS13140	COG0204	Acyl-transferase
CXL14_RS13145	COG1272	protein, Hemolysin III
CXL14_RS13150	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CXL14_RS13155	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CXL14_RS13165	COG1999	signal sequence binding
CXL14_RS13170	COG2755	lipolytic protein G-D-S-L family
CXL14_RS13175	COG4698	Protein conserved in bacteria
CXL14_RS13180	COG1846	Transcriptional regulator
CXL14_RS13195	COG1086	Polysaccharide biosynthesis protein
CXL14_RS13205	COG4641	Protein conserved in bacteria
CXL14_RS13220	COG0463	Glycosyl transferase, family 2
CXL14_RS13225	COG0456	acetyltransferase
CXL14_RS13235	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CXL14_RS13240	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CXL14_RS13245	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CXL14_RS13250	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CXL14_RS13255	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CXL14_RS13260	COG0456	acetyltransferase
CXL14_RS13265	COG1509	lysine 2,3-aminomutase activity
CXL14_RS13295	COG0671	phosphoesterase, PA-phosphatase related
CXL14_RS13315	COG1876	peptidase activity
CXL14_RS13325	COG2226	methyltransferase
CXL14_RS13330	COG3409	Peptidoglycan-binding domain 1 protein
CXL14_RS13330	COG0793	Belongs to the peptidase S41A family
CXL14_RS13335	COG2188	Transcriptional regulator
CXL14_RS13340	COG2723	6-phospho-beta-galactosidase activity
CXL14_RS13350	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CXL14_RS13360	COG0346	lactoylglutathione lyase activity
CXL14_RS13365	COG0400	carboxylic ester hydrolase activity
CXL14_RS13370	COG0778	Nitroreductase
CXL14_RS13375	COG1733	regulation of RNA biosynthetic process
CXL14_RS13385	COG1942	4-Oxalocrotonate Tautomerase
CXL14_RS13400	COG2962	Rard protein
CXL14_RS13410	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CXL14_RS13415	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CXL14_RS13420	COG1366	Belongs to the anti-sigma-factor antagonist family
CXL14_RS13425	COG0534	Mate efflux family protein
CXL14_RS13430	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CXL14_RS13435	COG1819	glycosyl
CXL14_RS13440	COG0791	NLP P60 protein
CXL14_RS13440	COG1388	LysM domain
CXL14_RS13445	COG2032	superoxide dismutase activity
CXL14_RS13450	COG0714	Associated with various cellular activities
CXL14_RS13455	COG4548	von Willebrand factor, type A
CXL14_RS13465	COG0508	dehydrogenase complex catalyzes the overall conversion of
CXL14_RS13470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CXL14_RS13475	COG0385	Bile acid
CXL14_RS13480	COG0733	neurotransmitter:sodium symporter activity
CXL14_RS13485	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CXL14_RS13490	COG1657	PFAM Prenyltransferase squalene oxidase
CXL14_RS13495	COG1012	belongs to the aldehyde dehydrogenase family
CXL14_RS13530	COG0071	Belongs to the small heat shock protein (HSP20) family
CXL14_RS13545	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CXL14_RS13550	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CXL14_RS13560	COG0514	ATP-dependent DNA helicase (RecQ)
CXL14_RS13565	COG3584	3D domain protein
CXL14_RS13565	COG1388	LysM domain
CXL14_RS13575	COG1619	proteins homologs of microcin C7 resistance protein MccF
CXL14_RS13590	COG2322	membrane
CXL14_RS13595	COG0741	lytic transglycosylase activity
CXL14_RS13600	COG0640	Transcriptional regulator
CXL14_RS13610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CXL14_RS13615	COG1309	transcriptional regulator
CXL14_RS13620	COG0662	Cupin 2, conserved barrel domain protein
CXL14_RS13620	COG2207	Transcriptional regulator
CXL14_RS13625	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CXL14_RS13630	COG5444	nuclease activity
CXL14_RS13660	COG0243	molybdopterin cofactor binding
CXL14_RS13665	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CXL14_RS13670	COG1070	Carbohydrate kinase
CXL14_RS13675	COG2814	Major facilitator Superfamily
CXL14_RS13685	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CXL14_RS13690	COG0300	oxidoreductase activity
CXL14_RS13705	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CXL14_RS13710	COG0583	DNA-binding transcription factor activity
CXL14_RS13715	COG0067	glutamate synthase
CXL14_RS13715	COG0069	glutamate synthase activity
CXL14_RS13715	COG0070	glutamate synthase
CXL14_RS13720	COG0493	'glutamate synthase
CXL14_RS13730	COG0604	alcohol dehydrogenase
CXL14_RS13740	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CXL14_RS13745	COG0640	Transcriptional regulator
CXL14_RS13750	COG2814	Major facilitator Superfamily
CXL14_RS13755	COG0405	Gamma-glutamyltransferase
CXL14_RS13760	COG0166	Belongs to the GPI family
CXL14_RS13765	COG0582	viral genome integration into host DNA
CXL14_RS13780	COG0534	Mate efflux family protein
CXL14_RS13785	COG2017	converts alpha-aldose to the beta-anomer
CXL14_RS13790	COG2027	D-alanyl-D-alanine carboxypeptidase
CXL14_RS13800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXL14_RS13805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXL14_RS13810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXL14_RS13815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXL14_RS13820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXL14_RS13820	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CXL14_RS13830	COG1649	PFAM Uncharacterised BCR, COG1649
CXL14_RS13835	COG1960	acyl-CoA dehydrogenase activity
CXL14_RS13840	COG0318	PFAM AMP-dependent synthetase and ligase
CXL14_RS13845	COG0439	Biotin carboxylase
CXL14_RS13850	COG0511	ligase activity, forming carbon-carbon bonds
CXL14_RS13855	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CXL14_RS13860	COG1024	Enoyl-CoA hydratase
CXL14_RS13865	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CXL14_RS13870	COG0586	Pfam SNARE associated Golgi protein
CXL14_RS13875	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CXL14_RS13880	COG2246	polysaccharide biosynthetic process
CXL14_RS13890	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CXL14_RS13910	COG2124	cytochrome p450
CXL14_RS13915	COG2610	gluconate transmembrane transporter activity
CXL14_RS13920	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CXL14_RS13925	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CXL14_RS13930	COG1028	Short-chain dehydrogenase reductase Sdr
CXL14_RS13960	COG3507	Belongs to the glycosyl hydrolase 43 family
CXL14_RS13970	COG0745	RESPONSE REGULATOR receiver
CXL14_RS13975	COG2205	protein histidine kinase activity
CXL14_RS14020	COG2271	Major facilitator Superfamily
CXL14_RS14025	COG1609	Transcriptional regulator
CXL14_RS14030	COG1028	Short-chain dehydrogenase reductase Sdr
CXL14_RS14040	COG0800	Aldolase
CXL14_RS14045	COG1063	alcohol dehydrogenase
CXL14_RS14055	COG1115	amino acid carrier protein
CXL14_RS14065	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CXL14_RS14070	COG0187	DNA topoisomerase II activity
CXL14_RS14075	COG1832	CoA-binding protein
CXL14_RS14085	COG4841	protein insertion into membrane
CXL14_RS14095	COG0824	Thioesterase
CXL14_RS14115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CXL14_RS14120	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CXL14_RS14135	COG0071	Belongs to the small heat shock protein (HSP20) family
CXL14_RS14145	COG4846	Membrane protein involved in cytochrome C biogenesis
CXL14_RS14150	COG2201	protein-glutamate methylesterase activity
CXL14_RS14155	COG0785	Cytochrome C biogenesis protein
CXL14_RS14175	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CXL14_RS14185	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CXL14_RS14215	COG4195	phage-related replication protein
CXL14_RS14220	COG0756	dUTP diphosphatase activity
CXL14_RS14230	COG5434	Belongs to the glycosyl hydrolase 28 family
CXL14_RS14240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CXL14_RS14250	COG3397	chitin binding
CXL14_RS14300	COG5444	nuclease activity
CXL14_RS14305	COG0456	acetyltransferase
CXL14_RS14330	COG1064	alcohol dehydrogenase
CXL14_RS14335	COG2318	DinB family
CXL14_RS14340	COG2378	regulation of single-species biofilm formation
CXL14_RS14365	COG0574	Belongs to the PEP-utilizing enzyme family
CXL14_RS14365	COG3848	Pyruvate phosphate dikinase
CXL14_RS14370	COG1070	Carbohydrate kinase
CXL14_RS14385	COG3507	Belongs to the glycosyl hydrolase 43 family
CXL14_RS14390	COG2211	Major facilitator Superfamily
CXL14_RS14425	COG0174	glutamine synthetase
CXL14_RS14430	COG0789	Transcriptional regulator
CXL14_RS14435	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CXL14_RS14440	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CXL14_RS14445	COG0464	growth
CXL14_RS14455	COG0860	N-Acetylmuramoyl-L-alanine amidase
CXL14_RS14460	COG4112	unkown
CXL14_RS14465	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CXL14_RS14470	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CXL14_RS14510	COG2076	Multidrug Resistance protein
CXL14_RS14520	COG1764	response to oxidative stress
CXL14_RS14525	COG4195	phage-related replication protein
CXL14_RS14535	COG1404	Belongs to the peptidase S8 family
CXL14_RS14545	COG3619	membrane
CXL14_RS14550	COG3209	COG3209 Rhs family protein
CXL14_RS14555	COG2124	cytochrome p450
CXL14_RS14560	COG3321	synthase
CXL14_RS14560	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CXL14_RS14560	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CXL14_RS14560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CXL14_RS14565	COG4221	oxidoreductase activity
CXL14_RS14565	COG1028	Short-chain dehydrogenase reductase Sdr
CXL14_RS14565	COG3321	synthase
CXL14_RS14565	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXL14_RS14570	COG3321	synthase
CXL14_RS14570	COG1028	Short-chain dehydrogenase reductase Sdr
CXL14_RS14570	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CXL14_RS14570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXL14_RS14570	COG3321	synthase
CXL14_RS14570	COG1028	Short-chain dehydrogenase reductase Sdr
CXL14_RS14570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXL14_RS14570	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CXL14_RS14570	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CXL14_RS14570	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CXL14_RS14575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CXL14_RS14575	COG3321	synthase
CXL14_RS14575	COG0300	oxidoreductase activity
CXL14_RS14575	COG4221	oxidoreductase activity
CXL14_RS14580	COG1028	Short-chain dehydrogenase reductase Sdr
CXL14_RS14580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXL14_RS14580	COG0318	PFAM AMP-dependent synthetase and ligase
CXL14_RS14580	COG3321	synthase
CXL14_RS14580	COG0300	oxidoreductase activity
CXL14_RS14585	COG1024	Enoyl-CoA hydratase
CXL14_RS14590	COG1024	Enoyl-CoA hydratase
CXL14_RS14595	COG3425	synthase
CXL14_RS14600	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CXL14_RS14675	COG4550	Control of competence regulator ComK, YlbF/YmcA
CXL14_RS14695	COG2359	stage V sporulation protein S
CXL14_RS14700	COG1692	metallophosphoesterase
CXL14_RS14710	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CXL14_RS14725	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CXL14_RS14730	COG1426	Protein conserved in bacteria
CXL14_RS14745	COG0300	oxidoreductase activity
CXL14_RS14750	COG0612	Peptidase, M16
CXL14_RS14755	COG0612	Peptidase, M16
CXL14_RS14760	COG1033	growth of symbiont in host cell
CXL14_RS14760	COG2409	Drug exporters of the RND superfamily
CXL14_RS14765	COG1846	Transcriptional regulator
CXL14_RS14770	COG2814	Major facilitator Superfamily
CXL14_RS14775	COG2188	Transcriptional regulator
CXL14_RS14780	COG4980	gas vesicle protein
CXL14_RS14780	COG1674	ftsk spoiiie
CXL14_RS14790	COG0740	serine-type endopeptidase activity
CXL14_RS14795	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CXL14_RS14805	COG0527	aspartate kinase activity
CXL14_RS14810	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CXL14_RS14815	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CXL14_RS14820	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CXL14_RS14825	COG1873	PFAM PRC-barrel domain
CXL14_RS14830	COG0612	Peptidase, M16
CXL14_RS14835	COG0726	polysaccharide deacetylase
CXL14_RS14850	COG0196	riboflavin kinase activity
CXL14_RS14865	COG1550	Protein conserved in bacteria
CXL14_RS14875	COG1358	cellular component organization or biogenesis
CXL14_RS14880	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CXL14_RS14885	COG0195	Participates in both transcription termination and antitermination
CXL14_RS14895	COG2176	DNA-directed DNA polymerase activity
CXL14_RS14905	COG0750	zinc metalloprotease
CXL14_RS14915	COG4589	Belongs to the CDS family
CXL14_RS14920	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CXL14_RS14950	COG1191	sigma factor activity
CXL14_RS14960	COG1776	CheC inhibitor of MCP methylation
CXL14_RS14965	COG0835	chemotaxis
CXL14_RS14970	COG2198	Histidine kinase
CXL14_RS14970	COG0643	Histidine kinase
CXL14_RS14975	COG2201	protein-glutamate methylesterase activity
CXL14_RS14980	COG0455	bacterial-type flagellum organization
CXL14_RS14985	COG1419	protein localization to endoplasmic reticulum
CXL14_RS14990	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CXL14_RS14995	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CXL14_RS15000	COG1684	flagellar biosynthetic protein fliR
CXL14_RS15005	COG1987	bacterial-type flagellum assembly
CXL14_RS15010	COG1338	Plays a role in the flagellum-specific transport system
CXL14_RS15015	COG3190	flagellar
CXL14_RS15020	COG2201	protein-glutamate methylesterase activity
CXL14_RS15025	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CXL14_RS15025	COG1776	CheC inhibitor of MCP methylation
CXL14_RS15030	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CXL14_RS15035	COG1580	Controls the rotational direction of flagella during chemotaxis
CXL14_RS15040	COG1582	Flagellar protein (FlbD)
CXL14_RS15045	COG4786	Flagellar basal body rod
CXL14_RS15050	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CXL14_RS15055	COG3144	bacterial-type flagellum assembly
CXL14_RS15060	COG3334	PFAM MgtE intracellular
CXL14_RS15065	COG2882	bacterial-type flagellum organization
CXL14_RS15070	COG1157	protein secretion by the type III secretion system
CXL14_RS15075	COG1317	bacterial-type flagellum organization
CXL14_RS15080	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CXL14_RS15085	COG1766	The M ring may be actively involved in energy transduction
CXL14_RS15090	COG1677	Flagellar hook-basal body complex protein FliE
CXL14_RS15095	COG1558	bacterial-type flagellum-dependent cell motility
CXL14_RS15100	COG1815	bacterial-type flagellum-dependent cell motility
CXL14_RS15120	COG4974	Belongs to the 'phage' integrase family
CXL14_RS15130	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CXL14_RS15135	COG0758	DNA mediated transformation
CXL14_RS15140	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CXL14_RS15150	COG2257	FlhB HrpN YscU SpaS Family
CXL14_RS15165	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CXL14_RS15190	COG1837	Belongs to the UPF0109 family
CXL14_RS15200	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CXL14_RS15215	COG0552	protein localization to endoplasmic reticulum
CXL14_RS15220	COG1196	nuclear chromosome segregation
CXL14_RS15235	COG1028	Short-chain dehydrogenase reductase Sdr
CXL14_RS15240	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CXL14_RS15255	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CXL14_RS15260	COG1760	l-serine dehydratase
CXL14_RS15265	COG1760	l-serine dehydratase
CXL14_RS15270	COG1461	Dihydroxyacetone kinase
CXL14_RS15275	COG1302	Protein conserved in bacteria
CXL14_RS15290	COG1564	THIamine pyrophosphokinase
CXL14_RS15295	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CXL14_RS15305	COG2815	serine threonine protein kinase
CXL14_RS15305	COG0515	serine threonine protein kinase
CXL14_RS15310	COG0631	protein serine/threonine phosphatase activity
CXL14_RS15320	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CXL14_RS15320	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CXL14_RS15330	COG0242	peptide deformylase activity
CXL14_RS15335	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CXL14_RS15340	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CXL14_RS15350	COG0194	GDP metabolic process
CXL14_RS15360	COG1561	YicC-like family, N-terminal region
CXL14_RS15365	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CXL14_RS15380	COG1648	precorrin-2 dehydrogenase activity
CXL14_RS15385	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
CXL14_RS15390	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CXL14_RS15405	COG0306	phosphate transporter
CXL14_RS15415	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CXL14_RS15420	COG0284	orotidine-5'-phosphate decarboxylase activity
CXL14_RS15435	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CXL14_RS15440	COG0505	Belongs to the CarA family
CXL14_RS15445	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CXL14_RS15455	COG2233	PERMEase
CXL14_RS15465	COG0564	pseudouridine synthase activity
CXL14_RS15475	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CXL14_RS15480	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CXL14_RS15490	COG3599	regulation of cell shape
CXL14_RS15495	COG2302	S4 RNA-binding domain
CXL14_RS15500	COG0762	integral membrane protein
CXL14_RS15510	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CXL14_RS15515	COG1496	oxidoreductase activity
CXL14_RS15520	COG1873	PFAM PRC-barrel domain
CXL14_RS15525	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CXL14_RS15530	COG1119	ATPase activity
CXL14_RS15535	COG1191	sigma factor activity
CXL14_RS15540	COG1191	sigma factor activity
CXL14_RS15550	COG4412	M6 family metalloprotease domain protein
CXL14_RS15550	COG1404	Belongs to the peptidase S8 family
CXL14_RS15555	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CXL14_RS15560	COG0849	cell division
CXL14_RS15565	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CXL14_RS15580	COG0772	Belongs to the SEDS family
CXL14_RS15600	COG0768	penicillin binding
CXL14_RS15605	COG0768	penicillin binding
CXL14_RS15610	COG4839	cell division protein FtsL
CXL14_RS15630	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CXL14_RS15650	COG1399	metal-binding, possibly nucleic acid-binding protein
CXL14_RS15660	COG3480	Lon protease (S16) C-terminal proteolytic domain
CXL14_RS15665	COG1752	Esterase of the alpha-beta hydrolase superfamily
CXL14_RS15670	COG3314	Sporulation integral membrane protein YlbJ
CXL14_RS15680	COG0742	ribosomal rna small subunit methyltransferase
CXL14_RS15695	COG3679	Belongs to the UPF0342 family
CXL14_RS15710	COG2340	Cysteine-rich secretory protein family
CXL14_RS15715	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CXL14_RS15725	COG3336	cytochrome c oxidase
CXL14_RS15730	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CXL14_RS15735	COG1845	cytochrome c oxidase, subunit III
CXL14_RS15740	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CXL14_RS15745	COG2010	Cytochrome c
CXL14_RS15745	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CXL14_RS15760	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CXL14_RS15765	COG0772	Belongs to the SEDS family
CXL14_RS15775	COG2066	Belongs to the glutaminase family
CXL14_RS15780	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CXL14_RS15785	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CXL14_RS15795	COG4896	Protein conserved in bacteria
CXL14_RS15805	COG1217	gtp-binding protein TYPA
CXL14_RS15830	COG3227	Zinc metalloprotease (Elastase)
CXL14_RS15840	COG0483	inositol monophosphate 1-phosphatase activity
CXL14_RS15865	COG1982	Orn Lys Arg decarboxylase major
CXL14_RS15880	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CXL14_RS15885	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CXL14_RS15890	COG0508	dehydrogenase complex catalyzes the overall conversion of
CXL14_RS15895	COG0022	dehydrogenase e1 component
CXL14_RS15900	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CXL14_RS15905	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CXL14_RS15910	COG1028	Short-chain dehydrogenase reductase Sdr
CXL14_RS15910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXL14_RS15910	COG3321	synthase
CXL14_RS15910	COG4221	oxidoreductase activity
CXL14_RS15915	COG4221	oxidoreductase activity
CXL14_RS15915	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CXL14_RS15915	COG3321	synthase
CXL14_RS15915	COG0300	oxidoreductase activity
CXL14_RS15920	COG0300	oxidoreductase activity
CXL14_RS15920	COG4221	oxidoreductase activity
CXL14_RS15920	COG3321	synthase
CXL14_RS15920	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CXL14_RS15925	COG4221	oxidoreductase activity
CXL14_RS15925	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CXL14_RS15925	COG0300	oxidoreductase activity
CXL14_RS15925	COG3321	synthase
CXL14_RS15930	COG3321	synthase
CXL14_RS15930	COG1028	Short-chain dehydrogenase reductase Sdr
CXL14_RS15930	COG4221	oxidoreductase activity
CXL14_RS15930	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXL14_RS15935	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CXL14_RS15935	COG0300	oxidoreductase activity
CXL14_RS15935	COG3321	synthase
CXL14_RS15935	COG4221	oxidoreductase activity
CXL14_RS15940	COG1028	Short-chain dehydrogenase reductase Sdr
CXL14_RS15940	COG3321	synthase
CXL14_RS15940	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXL14_RS15940	COG4221	oxidoreductase activity
CXL14_RS15955	COG0497	DNA recombination
CXL14_RS15965	COG0242	peptide deformylase activity
CXL14_RS15970	COG0561	phosphatase activity
CXL14_RS15985	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CXL14_RS15995	COG0569	domain protein
CXL14_RS16000	COG2105	PFAM AIG2 family protein
CXL14_RS16000	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CXL14_RS16005	COG3852	Histidine kinase
CXL14_RS16010	COG2002	toxin-antitoxin pair type II binding
CXL14_RS16020	COG1077	Cell shape determining protein MreB Mrl
CXL14_RS16030	COG2309	aminopeptidase activity
CXL14_RS16035	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CXL14_RS16040	COG0488	(ABC) transporter
CXL14_RS16050	COG0681	Belongs to the peptidase S26 family
CXL14_RS16055	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXL14_RS16055	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXL14_RS16055	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CXL14_RS16060	COG1105	Belongs to the carbohydrate kinase PfkB family
CXL14_RS16065	COG1349	DNA-binding transcription factor activity
CXL14_RS16070	COG0577	efflux transmembrane transporter activity
CXL14_RS16075	COG1136	(ABC) transporter
CXL14_RS16080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CXL14_RS16090	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CXL14_RS16095	COG0314	molybdopterin synthase activity
CXL14_RS16100	COG1763	Mo-molybdopterin cofactor biosynthetic process
CXL14_RS16105	COG0303	'Molybdopterin
CXL14_RS16110	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CXL14_RS16130	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CXL14_RS16135	COG0668	transmembrane transport
CXL14_RS16155	COG0716	FMN binding
CXL14_RS16165	COG0716	FMN binding
CXL14_RS16170	COG0583	DNA-binding transcription factor activity
CXL14_RS16175	COG0517	IMP dehydrogenase activity
CXL14_RS16185	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
CXL14_RS16190	COG4703	Protein of unknown function (DUF1797)
CXL14_RS16200	COG2200	EAL domain
CXL14_RS16210	COG1028	Short-chain dehydrogenase reductase Sdr
CXL14_RS16215	COG1408	metallophosphoesterase
CXL14_RS16220	COG1376	ErfK ybiS ycfS ynhG family protein
CXL14_RS16225	COG2814	Major facilitator Superfamily
CXL14_RS16235	COG0835	chemotaxis
CXL14_RS16235	COG0784	Response regulator, receiver
CXL14_RS16245	COG0436	Aminotransferase
CXL14_RS16250	COG4191	Histidine kinase
CXL14_RS16255	COG0768	penicillin binding
CXL14_RS16260	COG2340	Cysteine-rich secretory protein family
CXL14_RS16270	COG2084	Dehydrogenase
CXL14_RS16275	COG0840	transmembrane signaling receptor activity
CXL14_RS16280	COG1533	DNA photolyase activity
CXL14_RS16290	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CXL14_RS16295	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXL14_RS16300	COG2190	(PTS) system
CXL14_RS16300	COG1263	PTS System
CXL14_RS16300	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXL14_RS16305	COG3711	transcriptional antiterminator
CXL14_RS16310	COG1609	Transcriptional regulator
CXL14_RS16315	COG0006	proline dipeptidase activity
CXL14_RS16320	COG2217	Heavy metal translocating P-type atpase
CXL14_RS16325	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CXL14_RS16330	COG2244	polysaccharide biosynthetic process
CXL14_RS16335	COG3773	Cell wall hydrolase
CXL14_RS16345	COG4873	Protein conserved in bacteria
CXL14_RS16360	COG1028	Short-chain dehydrogenase reductase Sdr
CXL14_RS16365	COG1733	regulation of RNA biosynthetic process
CXL14_RS16375	COG0602	queuosine metabolic process
CXL14_RS16380	COG0720	synthase
CXL14_RS16395	COG3949	Membrane
CXL14_RS16405	COG0542	response to heat
CXL14_RS16410	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CXL14_RS16415	COG1360	Flagellar Motor Protein
CXL14_RS16420	COG1846	Transcriptional regulator
CXL14_RS16425	COG3852	Histidine kinase
CXL14_RS16455	COG0436	Aminotransferase
CXL14_RS16460	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CXL14_RS16475	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CXL14_RS16480	COG5002	protein histidine kinase activity
CXL14_RS16485	COG3594	Acyltransferase
CXL14_RS16495	COG2323	membrane
CXL14_RS16500	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CXL14_RS16525	COG1191	sigma factor activity
CXL14_RS16530	COG0861	Integral membrane protein TerC family
CXL14_RS16535	COG0586	Pfam SNARE associated Golgi protein
CXL14_RS16545	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CXL14_RS16550	COG3285	dna ligase
CXL14_RS16550	COG1793	dna ligase
CXL14_RS16555	COG0726	polysaccharide deacetylase
CXL14_RS16560	COG1846	Transcriptional regulator
CXL14_RS16575	COG0789	Transcriptional regulator
CXL14_RS16580	COG2239	Acts as a magnesium transporter
CXL14_RS16595	COG1388	LysM domain
CXL14_RS16595	COG3858	chitin binding
CXL14_RS16600	COG4721	ABC-type cobalt transport system, permease component
CXL14_RS16605	COG1122	ATPase activity
CXL14_RS16610	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CXL14_RS16615	COG1366	Belongs to the anti-sigma-factor antagonist family
CXL14_RS16620	COG1404	Belongs to the peptidase S8 family
CXL14_RS16630	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CXL14_RS16635	COG2814	Major facilitator Superfamily
CXL14_RS16645	COG0457	Tetratricopeptide repeat
CXL14_RS16645	COG0463	Glycosyl transferase, family 2
CXL14_RS16665	COG1764	response to oxidative stress
CXL14_RS16670	COG1846	Transcriptional regulator
CXL14_RS16675	COG1764	response to oxidative stress
CXL14_RS16685	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CXL14_RS16690	COG0788	formyltetrahydrofolate deformylase activity
CXL14_RS16695	COG2076	Multidrug Resistance protein
CXL14_RS16700	COG2076	Multidrug Resistance protein
CXL14_RS16705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CXL14_RS16710	COG1607	acyl-coa hydrolase
CXL14_RS16715	COG1834	amidinotransferase
CXL14_RS16720	COG2706	6-phosphogluconolactonase activity
CXL14_RS16725	COG4608	Belongs to the ABC transporter superfamily
CXL14_RS16730	COG0791	NLP P60 protein
CXL14_RS16735	COG4948	Mandelate Racemase Muconate Lactonizing
CXL14_RS16740	COG1619	proteins homologs of microcin C7 resistance protein MccF
CXL14_RS16745	COG4166	transmembrane transport
CXL14_RS16750	COG0444	Belongs to the ABC transporter superfamily
CXL14_RS16755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CXL14_RS16760	COG0601	transmembrane transport
CXL14_RS16765	COG2362	D-Aminopeptidase
CXL14_RS16770	COG0477	Major facilitator Superfamily
CXL14_RS16775	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CXL14_RS16780	COG0463	Glycosyl transferase, family 2
CXL14_RS16785	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CXL14_RS16790	COG0346	lactoylglutathione lyase activity
CXL14_RS16795	COG0531	amino acid
CXL14_RS16800	COG1392	Phosphate transport regulator
CXL14_RS16805	COG0306	phosphate transporter
CXL14_RS16820	COG3409	Peptidoglycan-binding domain 1 protein
CXL14_RS16820	COG5632	N-Acetylmuramoyl-L-alanine amidase
CXL14_RS16855	COG4193	domain, Protein
CXL14_RS16860	COG1595	DNA-templated transcription, initiation
CXL14_RS16875	COG1484	DNA-dependent DNA replication
CXL14_RS16880	COG1522	sequence-specific DNA binding
CXL14_RS16890	COG1396	sequence-specific DNA binding
CXL14_RS16895	COG2856	Zn peptidase
CXL14_RS16900	COG4195	phage-related replication protein
CXL14_RS16910	COG5632	N-Acetylmuramoyl-L-alanine amidase
CXL14_RS16910	COG3409	Peptidoglycan-binding domain 1 protein
CXL14_RS16910	COG1388	LysM domain
CXL14_RS16915	COG0457	Tetratricopeptide repeat
CXL14_RS16920	COG2318	DinB family
CXL14_RS16925	COG0730	response to heat
CXL14_RS16930	COG2721	sulfolactate sulfo-lyase activity
CXL14_RS16935	COG0246	Mannitol dehydrogenase
CXL14_RS16940	COG1609	Transcriptional regulator
CXL14_RS16945	COG2211	Major facilitator Superfamily
CXL14_RS16955	COG1252	NADH dehydrogenase
CXL14_RS16965	COG4297	protein containing double-stranded beta helix domain
CXL14_RS16970	COG0697	spore germination
CXL14_RS16975	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CXL14_RS16980	COG0390	transport system, permease component
CXL14_RS16985	COG1587	Uroporphyrinogen-III synthase
CXL14_RS16995	COG1819	glycosyl
CXL14_RS17000	COG2124	cytochrome p450
CXL14_RS17005	COG2427	Protein of unknown function (DUF1641)
CXL14_RS17010	COG3383	formate dehydrogenase (NAD+) activity
CXL14_RS17020	COG2205	protein histidine kinase activity
CXL14_RS17035	COG1285	pathogenesis
CXL14_RS17065	COG1447	Phosphotransferase system cellobiose-specific component IIA
CXL14_RS17070	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CXL14_RS17070	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CXL14_RS17075	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CXL14_RS17080	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CXL14_RS17085	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CXL14_RS17095	COG1846	Transcriptional regulator
CXL14_RS17100	COG0477	Major facilitator Superfamily
CXL14_RS17105	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CXL14_RS17110	COG2367	Beta-lactamase
CXL14_RS17125	COG0135	phosphoribosylanthranilate isomerase activity
CXL14_RS17145	COG5444	nuclease activity
CXL14_RS17175	COG0626	cystathionine gamma-synthase activity
CXL14_RS17180	COG0626	cystathionine gamma-synthase activity
CXL14_RS17185	COG2382	esterase
CXL14_RS17195	COG2153	protein acetylation
CXL14_RS17205	COG1131	(ABC) transporter
CXL14_RS17225	COG0210	DNA helicase
CXL14_RS17280	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CXL14_RS17285	COG0351	phosphomethylpyrimidine kinase
CXL14_RS17290	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CXL14_RS17300	COG2104	thiamine diphosphate biosynthetic process
CXL14_RS17305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CXL14_RS17310	COG0352	thiamine-phosphate diphosphorylase activity
CXL14_RS17315	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CXL14_RS17320	COG0569	domain protein
CXL14_RS17320	COG0475	glutathione-regulated potassium exporter activity
CXL14_RS17335	COG0564	pseudouridine synthase activity
CXL14_RS17340	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CXL14_RS17345	COG2357	RelA SpoT domain protein
CXL14_RS17355	COG4116	CYTH
CXL14_RS17360	COG0741	lytic transglycosylase activity
CXL14_RS17365	COG2346	COG2346, Truncated hemoglobins
CXL14_RS17370	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CXL14_RS17375	COG1164	Oligoendopeptidase f
CXL14_RS17380	COG4469	Competence protein
CXL14_RS17385	COG4862	establishment of competence for transformation
CXL14_RS17390	COG0861	Integral membrane protein TerC family
CXL14_RS17395	COG1393	Belongs to the ArsC family
CXL14_RS17400	COG0456	acetyltransferase
CXL14_RS17410	COG4608	Belongs to the ABC transporter superfamily
CXL14_RS17415	COG0444	Belongs to the ABC transporter superfamily
CXL14_RS17420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CXL14_RS17425	COG0601	transmembrane transport
CXL14_RS17430	COG4166	transmembrane transport
CXL14_RS17435	COG0180	Tryptophanyl-tRNA synthetase
CXL14_RS17445	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CXL14_RS17450	COG0601	transmembrane transport
CXL14_RS17460	COG4608	Belongs to the ABC transporter superfamily
CXL14_RS17465	COG0444	Belongs to the ABC transporter superfamily
CXL14_RS17470	COG5504	Zn-dependent protease
CXL14_RS17475	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CXL14_RS17480	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CXL14_RS17495	COG1744	ABC transporter substrate-binding protein PnrA-like
CXL14_RS17505	COG2267	carboxylic ester hydrolase activity
CXL14_RS17525	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CXL14_RS17530	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CXL14_RS17535	COG0505	Belongs to the CarA family
CXL14_RS17540	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CXL14_RS17550	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CXL14_RS17560	COG2271	Major facilitator Superfamily
CXL14_RS17565	COG0277	FAD linked oxidase domain protein
CXL14_RS17575	COG2151	metal-sulfur cluster biosynthetic enzyme
CXL14_RS17580	COG1073	alpha beta
CXL14_RS17585	COG0561	phosphatase activity
CXL14_RS17600	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CXL14_RS17605	COG1307	EDD domain protein, DegV family
CXL14_RS17615	COG2124	cytochrome p450
CXL14_RS17620	COG0840	transmembrane signaling receptor activity
CXL14_RS17625	COG1744	ABC transporter substrate-binding protein PnrA-like
CXL14_RS17630	COG2996	Protein conserved in bacteria
CXL14_RS17640	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CXL14_RS17640	COG0646	methionine synthase
CXL14_RS17645	COG2153	protein acetylation
CXL14_RS17650	COG1357	PFAM Pentapeptide repeats (8 copies)
CXL14_RS17655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CXL14_RS17660	COG1279	arginine transmembrane transporter activity
CXL14_RS17665	COG2318	DinB family
CXL14_RS17670	COG0673	inositol 2-dehydrogenase activity
CXL14_RS17675	COG1609	Transcriptional regulator
CXL14_RS17680	COG2207	Transcriptional regulator
CXL14_RS17680	COG1917	Cupin 2, conserved barrel domain protein
CXL14_RS17685	COG0534	Mate efflux family protein
CXL14_RS17690	COG1562	ergosterol biosynthetic process
CXL14_RS17695	COG0367	asparagine synthase
CXL14_RS17710	COG0179	Fumarylacetoacetate (FAA) hydrolase
CXL14_RS17750	COG1403	HNH endonuclease
CXL14_RS17755	COG0419	ATPase involved in DNA repair
CXL14_RS17760	COG0420	3'-5' exonuclease activity
CXL14_RS17775	COG2323	membrane
CXL14_RS17780	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
CXL14_RS17790	COG2814	Major facilitator Superfamily
CXL14_RS17795	COG3180	Ammonia monooxygenase
CXL14_RS17800	COG1846	Transcriptional regulator
CXL14_RS17805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CXL14_RS17810	COG0681	Belongs to the peptidase S26 family
CXL14_RS17815	COG0398	Pfam SNARE associated Golgi protein
CXL14_RS17830	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CXL14_RS17855	COG5646	InterPro IPR014922
CXL14_RS17860	COG4903	ComK protein
CXL14_RS17870	COG1028	Short-chain dehydrogenase reductase Sdr
CXL14_RS17875	COG0723	plastoquinol--plastocyanin reductase activity
CXL14_RS17875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CXL14_RS17880	COG0840	transmembrane signaling receptor activity
CXL14_RS17885	COG1268	BioY protein
CXL14_RS17890	COG0318	PFAM AMP-dependent synthetase and ligase
CXL14_RS17895	COG0183	Belongs to the thiolase family
CXL14_RS17900	COG0406	alpha-ribazole phosphatase activity
CXL14_RS17905	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CXL14_RS17915	COG1404	Belongs to the peptidase S8 family
CXL14_RS17920	COG0501	Belongs to the peptidase M48B family
CXL14_RS17930	COG0318	PFAM AMP-dependent synthetase and ligase
CXL14_RS17935	COG0702	epimerase
CXL14_RS17940	COG0095	Lipoate-protein ligase
CXL14_RS17945	COG1234	tRNA 3'-trailer cleavage
CXL14_RS17955	COG1301	dicarboxylic acid transport
CXL14_RS17960	COG1363	Peptidase, m42
CXL14_RS17970	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CXL14_RS17975	COG1511	domain protein
CXL14_RS17980	COG1309	transcriptional regulator
CXL14_RS17985	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CXL14_RS17990	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CXL14_RS18000	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CXL14_RS18005	COG2329	Antibiotic biosynthesis monooxygenase
CXL14_RS18010	COG3069	C4-dicarboxylate transmembrane transporter activity
CXL14_RS18015	COG1473	amidohydrolase
CXL14_RS18025	COG4473	ABC transporter
CXL14_RS18030	COG1131	(ABC) transporter
CXL14_RS18035	COG0537	adenosine 5'-monophosphoramidase activity
CXL14_RS18040	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CXL14_RS18055	COG4980	gas vesicle protein
CXL14_RS18095	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CXL14_RS18110	COG4717	serine-type aminopeptidase activity
CXL14_RS18115	COG0420	3'-5' exonuclease activity
CXL14_RS18120	COG1668	transmembrane transport
CXL14_RS18125	COG4152	abc transporter atp-binding protein
CXL14_RS18135	COG1024	Enoyl-CoA hydratase
CXL14_RS18145	COG0490	domain, Protein
CXL14_RS18150	COG0475	glutathione-regulated potassium exporter activity
CXL14_RS18160	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CXL14_RS18165	COG0561	phosphatase activity
CXL14_RS18170	COG4335	DNA alkylation repair
CXL14_RS18185	COG0189	ligase activity
CXL14_RS18190	COG0189	ligase activity
CXL14_RS18210	COG0702	epimerase
CXL14_RS18215	COG1132	(ABC) transporter
CXL14_RS18220	COG1132	(ABC) transporter
CXL14_RS18225	COG0589	response to stress
CXL14_RS18235	COG3226	Transcriptional regulator
CXL14_RS18240	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CXL14_RS18245	COG0726	polysaccharide deacetylase
CXL14_RS18250	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CXL14_RS18255	COG0668	transmembrane transport
CXL14_RS18265	COG0584	glycerophosphoryl diester phosphodiesterase
CXL14_RS18270	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CXL14_RS18275	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CXL14_RS18280	COG1253	flavin adenine dinucleotide binding
CXL14_RS18285	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CXL14_RS18290	COG0436	Aminotransferase
CXL14_RS18295	COG0789	Transcriptional regulator
CXL14_RS18300	COG1253	flavin adenine dinucleotide binding
CXL14_RS18305	COG0204	Acyl-transferase
CXL14_RS18310	COG1595	DNA-templated transcription, initiation
CXL14_RS18325	COG0733	neurotransmitter:sodium symporter activity
CXL14_RS18330	COG0531	amino acid
CXL14_RS18335	COG1028	Short-chain dehydrogenase reductase Sdr
CXL14_RS18340	COG0372	Belongs to the citrate synthase family
CXL14_RS18345	COG0583	DNA-binding transcription factor activity
CXL14_RS18350	COG0791	NLP P60 protein
CXL14_RS18350	COG1388	LysM domain
CXL14_RS18355	COG1785	Belongs to the alkaline phosphatase family
CXL14_RS18360	COG2719	SpoVR family
CXL14_RS18365	COG0668	transmembrane transport
CXL14_RS18370	COG1959	2 iron, 2 sulfur cluster binding
CXL14_RS18375	COG1388	LysM domain
CXL14_RS18375	COG0791	NLP P60 protein
CXL14_RS18390	COG0431	NADPH-dependent FMN reductase
CXL14_RS18395	COG2197	response regulator
CXL14_RS18400	COG4585	Histidine kinase
CXL14_RS18400	COG2203	Gaf domain
CXL14_RS18405	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CXL14_RS18410	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CXL14_RS18420	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CXL14_RS18425	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CXL14_RS18430	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CXL14_RS18435	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CXL14_RS18435	COG3153	acetyltransferase
CXL14_RS18440	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CXL14_RS18445	COG0517	IMP dehydrogenase activity
CXL14_RS18455	COG0564	pseudouridine synthase activity
CXL14_RS18460	COG3764	Sortase (surface protein transpeptidase)
CXL14_RS18465	COG0737	Belongs to the 5'-nucleotidase family
CXL14_RS18465	COG4085	toxin activity
CXL14_RS18465	COG1525	nuclease
CXL14_RS18470	COG5577	PFAM Coat F domain
CXL14_RS18490	COG1823	symporter activity
CXL14_RS18495	COG3706	GGDEF domain
CXL14_RS18500	COG1464	Belongs to the NlpA lipoprotein family
CXL14_RS18510	COG1278	Cold shock
CXL14_RS18515	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CXL14_RS18520	COG1131	(ABC) transporter
CXL14_RS18525	COG1131	(ABC) transporter
CXL14_RS18530	COG1725	Transcriptional regulator
CXL14_RS18545	COG0655	NAD(P)H dehydrogenase (quinone) activity
CXL14_RS18550	COG2814	Major facilitator Superfamily
CXL14_RS18555	COG1566	PFAM secretion protein HlyD family protein
CXL14_RS18560	COG1846	Transcriptional regulator
CXL14_RS18575	COG2766	serine protein kinase
CXL14_RS18585	COG1664	Polymer-forming cytoskeletal
CXL14_RS18590	COG1664	Polymer-forming cytoskeletal
CXL14_RS18595	COG0789	Transcriptional regulator
CXL14_RS18600	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CXL14_RS18610	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CXL14_RS18615	COG3382	B3 4 domain protein
CXL14_RS18625	COG1476	TRANSCRIPTIONal
CXL14_RS18645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CXL14_RS18650	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CXL14_RS18655	COG1116	anion transmembrane transporter activity
CXL14_RS18670	COG0753	catalase activity
CXL14_RS18675	COG4608	Belongs to the ABC transporter superfamily
CXL14_RS18680	COG0444	Belongs to the ABC transporter superfamily
CXL14_RS18685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CXL14_RS18690	COG0601	transmembrane transport
CXL14_RS18695	COG0747	negative chemotaxis
CXL14_RS18705	COG0277	FAD linked oxidase domain protein
CXL14_RS18715	COG3340	Belongs to the peptidase S51 family
CXL14_RS18740	COG5632	N-Acetylmuramoyl-L-alanine amidase
CXL14_RS18745	COG4824	toxin secretion phage lysis holin
CXL14_RS18765	COG5434	Belongs to the glycosyl hydrolase 28 family
CXL14_RS18780	COG3953	SLT domain
CXL14_RS18780	COG5412	phage tail tape measure protein
CXL14_RS18825	COG0740	serine-type endopeptidase activity
CXL14_RS18860	COG4980	gas vesicle protein
CXL14_RS18860	COG1674	ftsk spoiiie
CXL14_RS18865	COG0582	viral genome integration into host DNA
CXL14_RS18870	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CXL14_RS19065	COG0735	belongs to the Fur family
CXL14_RS19070	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CXL14_RS19080	COG4129	membrane
CXL14_RS19085	COG1132	(ABC) transporter
CXL14_RS19105	COG1028	Short-chain dehydrogenase reductase Sdr
CXL14_RS19115	COG1194	a g-specific adenine glycosylase
CXL14_RS19120	COG1988	membrane-bound metal-dependent
CXL14_RS19125	COG4485	Bacterial membrane protein, YfhO
CXL14_RS19130	COG0463	Glycosyl transferase, family 2
CXL14_RS19135	COG0596	Alpha beta hydrolase
CXL14_RS19140	COG5658	integral membrane protein
CXL14_RS19145	COG3103	Sh3 type 3 domain protein
CXL14_RS19160	COG3591	Belongs to the peptidase S1B family
CXL14_RS19170	COG2814	Major facilitator Superfamily
CXL14_RS19185	COG1090	epimerase
CXL14_RS19200	COG0778	Nitroreductase
CXL14_RS19205	COG0384	phenazine biosynthesis protein PhzF
CXL14_RS19210	COG0392	lysyltransferase activity
CXL14_RS19210	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CXL14_RS19215	COG1846	Transcriptional regulator
CXL14_RS19220	COG2814	Major facilitator Superfamily
CXL14_RS19225	COG2318	DinB family
CXL14_RS19230	COG2732	(Barnase) inhibitor
CXL14_RS19235	COG3848	Pyruvate phosphate dikinase
CXL14_RS19235	COG0574	Belongs to the PEP-utilizing enzyme family
CXL14_RS19245	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
CXL14_RS19250	COG2249	NAD(P)H dehydrogenase (quinone) activity
CXL14_RS19255	COG1695	Transcriptional regulator
CXL14_RS19270	COG2514	catechol 2,3-dioxygenase activity
CXL14_RS19275	COG2259	Doxx family
CXL14_RS19280	COG1132	(ABC) transporter
CXL14_RS19285	COG1132	(ABC) transporter
CXL14_RS19290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXL14_RS19290	COG1263	PTS System
CXL14_RS19295	COG1737	Transcriptional regulator
CXL14_RS19300	COG1486	melibiose metabolic process
CXL14_RS19310	COG3284	Transcriptional regulator
CXL14_RS19315	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CXL14_RS19320	COG0508	dehydrogenase complex catalyzes the overall conversion of
CXL14_RS19325	COG0022	dehydrogenase e1 component
CXL14_RS19330	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CXL14_RS19335	COG4637	Psort location Cytoplasmic, score
CXL14_RS19340	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CXL14_RS19355	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CXL14_RS19360	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CXL14_RS19365	COG0598	Magnesium transport protein CorA
CXL14_RS19375	COG2084	Dehydrogenase
CXL14_RS19380	COG0726	polysaccharide deacetylase
CXL14_RS19390	COG0535	radical SAM domain protein
CXL14_RS19395	COG0668	transmembrane transport
CXL14_RS19405	COG0387	Pfam Sodium calcium exchanger
CXL14_RS19410	COG0477	Major facilitator Superfamily
CXL14_RS19415	COG1295	ribonuclease BN
CXL14_RS19420	COG4980	gas vesicle protein
CXL14_RS19425	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CXL14_RS19435	COG2814	Major facilitator Superfamily
CXL14_RS19450	COG1609	Transcriptional regulator
CXL14_RS19455	COG0693	protein deglycase activity
CXL14_RS19460	COG0737	Belongs to the 5'-nucleotidase family
CXL14_RS19475	COG0778	Nitroreductase
CXL14_RS19480	COG2188	Transcriptional regulator
CXL14_RS19485	COG0366	Alpha amylase catalytic
CXL14_RS19490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXL14_RS19490	COG1263	PTS System
CXL14_RS19505	COG0071	Belongs to the small heat shock protein (HSP20) family
CXL14_RS19515	COG1368	sulfuric ester hydrolase activity
CXL14_RS19525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXL14_RS19525	COG1263	PTS System
CXL14_RS19530	COG0024	Methionine aminopeptidase
CXL14_RS19550	COG2258	MOSC domain
CXL14_RS19560	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
CXL14_RS19565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CXL14_RS19570	COG2851	Citrate transporter
CXL14_RS19575	COG3181	Tripartite tricarboxylate transporter family receptor
CXL14_RS19580	COG4565	transcriptional regulatory protein
CXL14_RS19585	COG3290	protein histidine kinase activity
CXL14_RS19590	COG3764	Sortase (surface protein transpeptidase)
CXL14_RS19600	COG3279	Response regulator of the LytR AlgR family
CXL14_RS19605	COG2972	Histidine kinase
CXL14_RS19605	COG0745	RESPONSE REGULATOR receiver
CXL14_RS19625	COG0471	metal ion transport
CXL14_RS19630	COG3866	Pectate lyase
CXL14_RS19645	COG2130	NADP-dependent
CXL14_RS19650	COG0456	acetyltransferase
CXL14_RS19655	COG0513	Belongs to the DEAD box helicase family
CXL14_RS19660	COG0488	(ABC) transporter
CXL14_RS19665	COG2814	Major facilitator Superfamily
CXL14_RS19670	COG0789	Transcriptional regulator
CXL14_RS19675	COG0488	(ABC) transporter
CXL14_RS19680	COG0463	Glycosyl transferase, family 2
CXL14_RS19680	COG0457	Tetratricopeptide repeat
CXL14_RS19685	COG1028	Short-chain dehydrogenase reductase Sdr
CXL14_RS19690	COG0840	transmembrane signaling receptor activity
CXL14_RS19695	COG1012	belongs to the aldehyde dehydrogenase family
CXL14_RS19700	COG0531	amino acid
CXL14_RS19705	COG2223	nitrite transmembrane transporter activity
CXL14_RS19710	COG1442	glycosyl transferase family 8
CXL14_RS19715	COG1216	Glycosyl transferase, family 2
CXL14_RS19720	COG1442	glycosyl transferase family 8
CXL14_RS19725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CXL14_RS19730	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CXL14_RS19735	COG1368	sulfuric ester hydrolase activity
CXL14_RS19740	COG2124	cytochrome p450
CXL14_RS19740	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CXL14_RS19750	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CXL14_RS19755	COG1846	Transcriptional regulator
CXL14_RS19760	COG0670	Belongs to the BI1 family
CXL14_RS19765	COG0196	riboflavin kinase activity
CXL14_RS19770	COG5583	Uncharacterized small protein (DUF2292)
CXL14_RS19775	COG1366	Belongs to the anti-sigma-factor antagonist family
CXL14_RS19780	COG0346	lactoylglutathione lyase activity
CXL14_RS19785	COG2329	Antibiotic biosynthesis monooxygenase
CXL14_RS19790	COG2323	membrane
CXL14_RS19800	COG0454	-acetyltransferase
CXL14_RS19805	COG3546	catalase activity
CXL14_RS19880	COG1131	(ABC) transporter
CXL14_RS19890	COG1136	(ABC) transporter
CXL14_RS19895	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CXL14_RS19900	COG1597	lipid kinase activity
CXL14_RS19905	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CXL14_RS19910	COG1309	transcriptional regulator
CXL14_RS19930	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CXL14_RS19935	COG1285	pathogenesis
CXL14_RS19940	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CXL14_RS19945	COG4851	CamS sex pheromone cAM373 precursor
CXL14_RS19955	COG0210	DNA helicase
CXL14_RS19970	COG0069	glutamate synthase activity
CXL14_RS19975	COG4496	protein, YerC YecD
CXL14_RS19980	COG1470	cell adhesion involved in biofilm formation
CXL14_RS19985	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CXL14_RS19995	COG0151	Belongs to the GarS family
CXL14_RS20000	COG0138	bifunctional purine biosynthesis protein purh
CXL14_RS20005	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CXL14_RS20015	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CXL14_RS20030	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL