locus-tag	class	description
I7V34_RS00010	COG3290	protein histidine kinase activity
I7V34_RS00015	COG3279	Response regulator of the LytR AlgR family
I7V34_RS00020	COG4555	ABC transporter
I7V34_RS00025	COG1668	transmembrane transport
I7V34_RS00035	COG2311	Membrane
I7V34_RS00045	COG1278	Cold shock
I7V34_RS00055	COG1278	Cold shock
I7V34_RS00060	COG0745	RESPONSE REGULATOR receiver
I7V34_RS00065	COG3850	Histidine kinase
I7V34_RS00065	COG5002	protein histidine kinase activity
I7V34_RS00070	COG0577	efflux transmembrane transporter activity
I7V34_RS00075	COG1136	(ABC) transporter
I7V34_RS00080	COG3682	Transcriptional regulator
I7V34_RS00090	COG2217	Heavy metal translocating P-type atpase
I7V34_RS00120	COG0366	Alpha amylase catalytic
I7V34_RS00125	COG0395	ABC-type sugar transport system, permease component
I7V34_RS00135	COG2182	Extracellular solute-binding protein
I7V34_RS00145	COG3459	Glycosyltransferase 36 associated
I7V34_RS00150	COG3663	DNA glycosylase
I7V34_RS00170	COG0438	transferase activity, transferring glycosyl groups
I7V34_RS00180	COG0463	Glycosyl transferase, family 2
I7V34_RS00210	COG1012	belongs to the aldehyde dehydrogenase family
I7V34_RS00215	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
I7V34_RS00225	COG1028	Short-chain dehydrogenase reductase Sdr
I7V34_RS00230	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
I7V34_RS00235	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
I7V34_RS00250	COG2346	COG2346, Truncated hemoglobins
I7V34_RS00255	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
I7V34_RS00260	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
I7V34_RS00265	COG0535	radical SAM domain protein
I7V34_RS00275	COG0489	protein tyrosine kinase activity
I7V34_RS00285	COG0243	molybdopterin cofactor binding
I7V34_RS00290	COG0437	4 iron, 4 sulfur cluster binding
I7V34_RS00295	COG4638	Rieske (2fe-2S)
I7V34_RS00310	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
I7V34_RS00315	COG0303	'Molybdopterin
I7V34_RS00320	COG0314	molybdopterin synthase activity
I7V34_RS00335	COG0521	Mo-molybdopterin cofactor biosynthetic process
I7V34_RS00340	COG0725	ABC transporter, periplasmic molybdate-binding protein
I7V34_RS00345	COG4149	molybdate abc transporter
I7V34_RS00360	COG2223	nitrite transmembrane transporter activity
I7V34_RS00370	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
I7V34_RS00375	COG0746	molybdenum cofactor guanylyltransferase activity
I7V34_RS00380	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
I7V34_RS00390	COG1657	PFAM Prenyltransferase squalene oxidase
I7V34_RS00410	COG1115	amino acid carrier protein
I7V34_RS00415	COG3152	Membrane
I7V34_RS00425	COG1012	belongs to the aldehyde dehydrogenase family
I7V34_RS00435	COG1454	alcohol dehydrogenase
I7V34_RS00440	COG3829	transcription factor binding
I7V34_RS00440	COG3290	protein histidine kinase activity
I7V34_RS00455	COG3832	glyoxalase III activity
I7V34_RS00505	COG2207	Transcriptional regulator
I7V34_RS00505	COG3708	Transcriptional regulator
I7V34_RS00515	COG2186	Transcriptional regulator
I7V34_RS00520	COG1620	l-lactate permease
I7V34_RS00525	COG0247	lactate metabolic process
I7V34_RS00530	COG1139	Iron-sulfur cluster binding protein
I7V34_RS00535	COG1556	Lactate utilization protein
I7V34_RS00560	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
I7V34_RS00580	COG2205	protein histidine kinase activity
I7V34_RS00585	COG0778	Nitroreductase
I7V34_RS00600	COG1268	BioY protein
I7V34_RS00605	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
I7V34_RS00610	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
I7V34_RS00615	COG0247	lactate metabolic process
I7V34_RS00620	COG0277	FAD linked oxidase domain protein
I7V34_RS00635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I7V34_RS00635	COG1263	PTS System
I7V34_RS00640	COG2188	Transcriptional regulator
I7V34_RS00645	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
I7V34_RS00650	COG0363	glucosamine-6-phosphate deaminase activity
I7V34_RS00655	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
I7V34_RS00660	COG0070	glutamate synthase
I7V34_RS00660	COG0069	glutamate synthase activity
I7V34_RS00660	COG0067	glutamate synthase
I7V34_RS00665	COG0493	'glutamate synthase
I7V34_RS00670	COG1263	PTS System
I7V34_RS00670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I7V34_RS00680	COG1595	DNA-templated transcription, initiation
I7V34_RS00695	COG3290	protein histidine kinase activity
I7V34_RS00700	COG4565	transcriptional regulatory protein
I7V34_RS00705	COG3181	Tripartite tricarboxylate transporter family receptor
I7V34_RS00720	COG1053	succinate dehydrogenase
I7V34_RS00730	COG1607	acyl-coa hydrolase
I7V34_RS00735	COG2268	Band 7 protein
I7V34_RS00750	COG0737	Belongs to the 5'-nucleotidase family
I7V34_RS00760	COG1073	alpha beta
I7V34_RS00770	COG0277	FAD linked oxidase domain protein
I7V34_RS00775	COG0385	Bile acid
I7V34_RS00780	COG2031	fatty acid transporter
I7V34_RS00785	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I7V34_RS00790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I7V34_RS00795	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
I7V34_RS00800	COG1120	ATPase activity
I7V34_RS00805	COG0492	ferredoxin-NADP+ reductase activity
I7V34_RS00810	COG0861	Integral membrane protein TerC family
I7V34_RS00820	COG2832	Protein of unknown function (DUF454)
I7V34_RS00835	COG0697	spore germination
I7V34_RS00850	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
I7V34_RS00855	COG2270	Major facilitator Superfamily
I7V34_RS00870	COG0586	Pfam SNARE associated Golgi protein
I7V34_RS00875	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
I7V34_RS00880	COG1664	Polymer-forming cytoskeletal
I7V34_RS00885	COG0789	Transcriptional regulator
I7V34_RS00895	COG0753	catalase activity
I7V34_RS00910	COG0542	response to heat
I7V34_RS00915	COG0561	phosphatase activity
I7V34_RS00925	COG3706	GGDEF domain
I7V34_RS00955	COG1090	epimerase
I7V34_RS00990	COG1988	membrane-bound metal-dependent
I7V34_RS01000	COG1194	a g-specific adenine glycosylase
I7V34_RS01010	COG1028	Short-chain dehydrogenase reductase Sdr
I7V34_RS01025	COG3557	Belongs to the UPF0374 family
I7V34_RS01030	COG1132	(ABC) transporter
I7V34_RS01035	COG0444	Belongs to the ABC transporter superfamily
I7V34_RS01040	COG4608	Belongs to the ABC transporter superfamily
I7V34_RS01045	COG0747	negative chemotaxis
I7V34_RS01050	COG0601	transmembrane transport
I7V34_RS01055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
I7V34_RS01060	COG4129	membrane
I7V34_RS01065	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
I7V34_RS01075	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
I7V34_RS01080	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
I7V34_RS01085	COG2096	Adenosyltransferase
I7V34_RS01090	COG0735	belongs to the Fur family
I7V34_RS01215	COG2972	Histidine kinase
I7V34_RS01230	COG0673	inositol 2-dehydrogenase activity
I7V34_RS01235	COG0673	inositol 2-dehydrogenase activity
I7V34_RS01240	COG1082	Xylose isomerase domain protein TIM barrel
I7V34_RS01245	COG3382	B3 4 domain protein
I7V34_RS01250	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
I7V34_RS01260	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
I7V34_RS01265	COG0778	Nitroreductase
I7V34_RS01270	COG2766	serine protein kinase
I7V34_RS01285	COG2718	Belongs to the UPF0229 family
I7V34_RS01300	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
I7V34_RS01310	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
I7V34_RS01345	COG2252	PERMEase
I7V34_RS01350	COG4187	Peptidase family M20/M25/M40
I7V34_RS01355	COG0778	Nitroreductase
I7V34_RS01360	COG1609	Transcriptional regulator
I7V34_RS01365	COG1970	mechanosensitive ion channel activity
I7V34_RS01375	COG3973	AAA domain
I7V34_RS01390	COG0656	L-ascorbic acid biosynthetic process
I7V34_RS01395	COG0655	NAD(P)H dehydrogenase (quinone) activity
I7V34_RS01400	COG0564	pseudouridine synthase activity
I7V34_RS01410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I7V34_RS01415	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
I7V34_RS01420	COG3153	acetyltransferase
I7V34_RS01420	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
I7V34_RS01425	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
I7V34_RS01430	COG1028	Short-chain dehydrogenase reductase Sdr
I7V34_RS01435	COG2203	Gaf domain
I7V34_RS01435	COG4585	Histidine kinase
I7V34_RS01440	COG2197	response regulator
I7V34_RS01445	COG0431	NADPH-dependent FMN reductase
I7V34_RS01460	COG2211	Major facilitator Superfamily
I7V34_RS01465	COG2719	SpoVR family
I7V34_RS01475	COG2364	Membrane
I7V34_RS01480	COG1028	Short-chain dehydrogenase reductase Sdr
I7V34_RS01485	COG2610	gluconate transmembrane transporter activity
I7V34_RS01500	COG4989	oxidoreductase activity
I7V34_RS01515	COG1533	DNA photolyase activity
I7V34_RS01525	COG1301	dicarboxylic acid transport
I7V34_RS01545	COG2814	Major facilitator Superfamily
I7V34_RS01550	COG1595	DNA-templated transcription, initiation
I7V34_RS01565	COG0393	Putative heavy-metal-binding
I7V34_RS01570	COG1132	(ABC) transporter
I7V34_RS01575	COG1132	(ABC) transporter
I7V34_RS01585	COG0702	epimerase
I7V34_RS01590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I7V34_RS01595	COG0765	amino acid transport
I7V34_RS01600	COG1126	abc transporter atp-binding protein
I7V34_RS01630	COG3842	ATPase activity
I7V34_RS01635	COG2508	Transcriptional regulator
I7V34_RS01640	COG1937	Protein conserved in bacteria
I7V34_RS01665	COG0189	ligase activity
I7V34_RS01670	COG0189	ligase activity
I7V34_RS01675	COG0189	ligase activity
I7V34_RS01680	COG4399	Belongs to the UPF0754 family
I7V34_RS01685	COG3679	Belongs to the UPF0342 family
I7V34_RS01690	COG0561	phosphatase activity
I7V34_RS01695	COG0635	Involved in the biosynthesis of porphyrin-containing compound
I7V34_RS01700	COG0318	PFAM AMP-dependent synthetase and ligase
I7V34_RS01705	COG1024	Enoyl-CoA hydratase
I7V34_RS01720	COG4152	abc transporter atp-binding protein
I7V34_RS01725	COG1668	transmembrane transport
I7V34_RS01730	COG0420	3'-5' exonuclease activity
I7V34_RS01735	COG4717	serine-type aminopeptidase activity
I7V34_RS01740	COG3481	metal-dependent phosphohydrolase, HD sub domain
I7V34_RS01750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
I7V34_RS01775	COG1846	Transcriptional regulator
I7V34_RS01795	COG0537	adenosine 5'-monophosphoramidase activity
I7V34_RS01800	COG1131	(ABC) transporter
I7V34_RS01805	COG4473	ABC transporter
I7V34_RS01815	COG1473	amidohydrolase
I7V34_RS01825	COG3069	C4-dicarboxylate transmembrane transporter activity
I7V34_RS01835	COG4585	Histidine kinase
I7V34_RS01840	COG2197	response regulator
I7V34_RS01845	COG2329	Antibiotic biosynthesis monooxygenase
I7V34_RS01850	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
I7V34_RS01855	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
I7V34_RS01860	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
I7V34_RS01870	COG1309	transcriptional regulator
I7V34_RS01875	COG1511	domain protein
I7V34_RS01890	COG1234	tRNA 3'-trailer cleavage
I7V34_RS01895	COG0095	Lipoate-protein ligase
I7V34_RS01905	COG0318	PFAM AMP-dependent synthetase and ligase
I7V34_RS01910	COG1024	Enoyl-CoA hydratase
I7V34_RS01920	COG2391	methyltransferase activity
I7V34_RS01925	COG1396	sequence-specific DNA binding
I7V34_RS01930	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
I7V34_RS01940	COG0501	Belongs to the peptidase M48B family
I7V34_RS01945	COG2323	membrane
I7V34_RS01955	COG4903	ComK protein
I7V34_RS01965	COG4946	Tricorn protease homolog
I7V34_RS01965	COG0823	Involved in the tonB-independent uptake of proteins
I7V34_RS01965	COG1506	peptidase
I7V34_RS01970	COG0398	Pfam SNARE associated Golgi protein
I7V34_RS01980	COG2909	trisaccharide binding
I7V34_RS02010	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
I7V34_RS02020	COG1028	Short-chain dehydrogenase reductase Sdr
I7V34_RS02025	COG0183	Belongs to the thiolase family
I7V34_RS02030	COG2356	endonuclease I
I7V34_RS02035	COG0318	PFAM AMP-dependent synthetase and ligase
I7V34_RS02045	COG2814	Major facilitator Superfamily
I7V34_RS02050	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
I7V34_RS02055	COG1074	ATP-dependent DNA helicase activity
I7V34_RS02060	COG1403	HNH endonuclease
I7V34_RS02095	COG2311	Membrane
I7V34_RS02100	COG0179	Fumarylacetoacetate (FAA) hydrolase
I7V34_RS02120	COG0367	asparagine synthase
I7V34_RS02125	COG0004	ammonium transporteR
I7V34_RS02130	COG0347	Belongs to the P(II) protein family
I7V34_RS02135	COG0534	Mate efflux family protein
I7V34_RS02145	COG2182	Extracellular solute-binding protein
I7V34_RS02150	COG1175	transmembrane transport
I7V34_RS02155	COG3833	ABC-type maltose transport systems, permease component
I7V34_RS02165	COG1609	Transcriptional regulator
I7V34_RS02170	COG1028	Short-chain dehydrogenase reductase Sdr
I7V34_RS02175	COG0446	pyridine nucleotide-disulphide oxidoreductase
I7V34_RS02180	COG1666	GTP binding
I7V34_RS02190	COG1307	EDD domain protein, DegV family
I7V34_RS02195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
I7V34_RS02210	COG0561	phosphatase activity
I7V34_RS02215	COG1073	alpha beta
I7V34_RS02220	COG2151	metal-sulfur cluster biosynthetic enzyme
I7V34_RS02245	COG2267	carboxylic ester hydrolase activity
I7V34_RS02255	COG1744	ABC transporter substrate-binding protein PnrA-like
I7V34_RS02265	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
I7V34_RS02270	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
I7V34_RS02275	COG5504	Zn-dependent protease
I7V34_RS02290	COG0180	Tryptophanyl-tRNA synthetase
I7V34_RS02300	COG4166	transmembrane transport
I7V34_RS02305	COG0601	transmembrane transport
I7V34_RS02310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
I7V34_RS02315	COG0444	Belongs to the ABC transporter superfamily
I7V34_RS02320	COG4608	Belongs to the ABC transporter superfamily
I7V34_RS02330	COG0456	acetyltransferase
I7V34_RS02335	COG1393	Belongs to the ArsC family
I7V34_RS02340	COG4862	establishment of competence for transformation
I7V34_RS02345	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
I7V34_RS02355	COG1164	Oligoendopeptidase f
I7V34_RS02365	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
I7V34_RS02370	COG2346	COG2346, Truncated hemoglobins
I7V34_RS02375	COG0741	lytic transglycosylase activity
I7V34_RS02380	COG4116	CYTH
I7V34_RS02390	COG2357	RelA SpoT domain protein
I7V34_RS02400	COG0564	pseudouridine synthase activity
I7V34_RS02405	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
I7V34_RS02410	COG2239	Acts as a magnesium transporter
I7V34_RS02415	COG0475	glutathione-regulated potassium exporter activity
I7V34_RS02415	COG0569	domain protein
I7V34_RS02455	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
I7V34_RS02465	COG2323	membrane
I7V34_RS02485	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
I7V34_RS02490	COG2323	membrane
I7V34_RS02495	COG2153	protein acetylation
I7V34_RS02500	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
I7V34_RS02505	COG2382	esterase
I7V34_RS02510	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
I7V34_RS02515	COG2358	TRAP transporter, solute receptor (TAXI family
I7V34_RS02555	COG1960	acyl-CoA dehydrogenase activity
I7V34_RS02560	COG0183	Belongs to the thiolase family
I7V34_RS02565	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
I7V34_RS02580	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
I7V34_RS02585	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
I7V34_RS02595	COG1764	response to oxidative stress
I7V34_RS02605	COG1295	ribonuclease BN
I7V34_RS02610	COG3104	oligopeptide transport
I7V34_RS02615	COG1363	Peptidase, m42
I7V34_RS02620	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
I7V34_RS02625	COG3706	GGDEF domain
I7V34_RS02630	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
I7V34_RS02640	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
I7V34_RS02645	COG5001	Diguanylate cyclase
I7V34_RS02645	COG3300	MHYT domain
I7V34_RS02650	COG1757	Na H antiporter
I7V34_RS02670	COG0861	Integral membrane protein TerC family
I7V34_RS02680	COG1191	sigma factor activity
I7V34_RS02695	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
I7V34_RS02715	COG3594	Acyltransferase
I7V34_RS02720	COG5002	protein histidine kinase activity
I7V34_RS02725	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
I7V34_RS02730	COG0640	Transcriptional regulator
I7V34_RS02735	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
I7V34_RS02740	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
I7V34_RS02745	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
I7V34_RS02750	COG0436	Aminotransferase
I7V34_RS02755	COG1850	ribulose-bisphosphate carboxylase activity
I7V34_RS02760	COG0235	Class ii aldolase
I7V34_RS02780	COG1846	Transcriptional regulator
I7V34_RS02790	COG3949	Membrane
I7V34_RS02800	COG4873	Protein conserved in bacteria
I7V34_RS02810	COG3773	Cell wall hydrolase
I7V34_RS02815	COG1028	Short-chain dehydrogenase reductase Sdr
I7V34_RS02820	COG0714	Associated with various cellular activities
I7V34_RS02835	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
I7V34_RS02840	COG0390	transport system, permease component
I7V34_RS02855	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
I7V34_RS02860	COG0456	acetyltransferase
I7V34_RS02870	COG0436	Aminotransferase
I7V34_RS02875	COG0598	Magnesium transport protein CorA
I7V34_RS02885	COG0720	synthase
I7V34_RS02890	COG0602	queuosine metabolic process
I7V34_RS02900	COG0784	Response regulator, receiver
I7V34_RS02900	COG0835	chemotaxis
I7V34_RS02915	COG3300	MHYT domain
I7V34_RS02915	COG5001	Diguanylate cyclase
I7V34_RS02925	COG1028	Short-chain dehydrogenase reductase Sdr
I7V34_RS02930	COG2200	EAL domain
I7V34_RS02950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I7V34_RS02955	COG4703	Protein of unknown function (DUF1797)
I7V34_RS02960	COG0517	IMP dehydrogenase activity
I7V34_RS02965	COG0477	Major facilitator Superfamily
I7V34_RS02975	COG0583	DNA-binding transcription factor activity
I7V34_RS02985	COG1473	amidohydrolase
I7V34_RS02990	COG0668	transmembrane transport
I7V34_RS02995	COG1132	(ABC) transporter
I7V34_RS03000	COG1132	(ABC) transporter
I7V34_RS03010	COG1271	oxidase subunit
I7V34_RS03015	COG1294	oxidase, subunit
I7V34_RS03020	COG0569	domain protein
I7V34_RS03025	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
I7V34_RS03035	COG0561	phosphatase activity
I7V34_RS03040	COG0242	peptide deformylase activity
I7V34_RS03055	COG0022	dehydrogenase e1 component
I7V34_RS03060	COG0508	dehydrogenase complex catalyzes the overall conversion of
I7V34_RS03070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I7V34_RS03075	COG0726	polysaccharide deacetylase
I7V34_RS03085	COG1982	Orn Lys Arg decarboxylase major
I7V34_RS03095	COG4476	Belongs to the UPF0223 family
I7V34_RS03100	COG4493	Belongs to the UPF0637 family
I7V34_RS03110	COG0483	inositol monophosphate 1-phosphatase activity
I7V34_RS03120	COG1217	gtp-binding protein TYPA
I7V34_RS03135	COG4896	Protein conserved in bacteria
I7V34_RS03150	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
I7V34_RS03155	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
I7V34_RS03160	COG2066	Belongs to the glutaminase family
I7V34_RS03170	COG0772	Belongs to the SEDS family
I7V34_RS03175	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
I7V34_RS03200	COG1845	cytochrome c oxidase, subunit III
I7V34_RS03225	COG3336	cytochrome c oxidase
I7V34_RS03240	COG0628	permease
I7V34_RS03250	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
I7V34_RS03255	COG2340	Cysteine-rich secretory protein family
I7V34_RS03280	COG3679	Belongs to the UPF0342 family
I7V34_RS03300	COG0742	ribosomal rna small subunit methyltransferase
I7V34_RS03305	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
I7V34_RS03310	COG3314	Sporulation integral membrane protein YlbJ
I7V34_RS03315	COG1752	Esterase of the alpha-beta hydrolase superfamily
I7V34_RS03320	COG3480	Lon protease (S16) C-terminal proteolytic domain
I7V34_RS03330	COG1399	metal-binding, possibly nucleic acid-binding protein
I7V34_RS03335	COG0333	Belongs to the bacterial ribosomal protein bL32 family
I7V34_RS03340	COG1024	Enoyl-CoA hydratase
I7V34_RS03350	COG0454	-acetyltransferase
I7V34_RS03355	COG0439	Biotin carboxylase
I7V34_RS03360	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
I7V34_RS03365	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
I7V34_RS03370	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
I7V34_RS03380	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
I7V34_RS03385	COG2001	Belongs to the MraZ family
I7V34_RS03390	COG0275	rRNA processing
I7V34_RS03400	COG0768	penicillin binding
I7V34_RS03405	COG0768	penicillin binding
I7V34_RS03420	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
I7V34_RS03425	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
I7V34_RS03430	COG0772	Belongs to the SEDS family
I7V34_RS03435	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
I7V34_RS03440	COG3879	Bacterial protein of unknown function (DUF881)
I7V34_RS03445	COG3879	Bacterial protein of unknown function (DUF881)
I7V34_RS03450	COG3856	small basic protein
I7V34_RS03455	COG0849	cell division
I7V34_RS03460	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
I7V34_RS03470	COG1191	sigma factor activity
I7V34_RS03475	COG1191	sigma factor activity
I7V34_RS03480	COG1873	PFAM PRC-barrel domain
I7V34_RS03485	COG1496	oxidoreductase activity
I7V34_RS03490	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
I7V34_RS03495	COG1799	cell septum assembly
I7V34_RS03500	COG0762	integral membrane protein
I7V34_RS03505	COG2302	S4 RNA-binding domain
I7V34_RS03510	COG3599	regulation of cell shape
I7V34_RS03520	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
I7V34_RS03525	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
I7V34_RS03530	COG0564	pseudouridine synthase activity
I7V34_RS03535	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
I7V34_RS03550	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
I7V34_RS03565	COG0543	2 iron, 2 sulfur cluster binding
I7V34_RS03570	COG0167	dihydroorotate dehydrogenase activity
I7V34_RS03575	COG0284	orotidine-5'-phosphate decarboxylase activity
I7V34_RS03580	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
I7V34_RS03590	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
I7V34_RS03595	COG1561	YicC-like family, N-terminal region
I7V34_RS03605	COG0194	GDP metabolic process
I7V34_RS03615	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
I7V34_RS03620	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
I7V34_RS03625	COG0242	peptide deformylase activity
I7V34_RS03630	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
I7V34_RS03635	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
I7V34_RS03635	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
I7V34_RS03645	COG0515	serine threonine protein kinase
I7V34_RS03645	COG2815	serine threonine protein kinase
I7V34_RS03650	COG1162	GTPase activity
I7V34_RS03655	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
I7V34_RS03660	COG1564	THIamine pyrophosphokinase
I7V34_RS03670	COG0227	Belongs to the bacterial ribosomal protein bL28 family
I7V34_RS03675	COG1302	Protein conserved in bacteria
I7V34_RS03680	COG1461	Dihydroxyacetone kinase
I7V34_RS03685	COG1760	l-serine dehydratase
I7V34_RS03690	COG1760	l-serine dehydratase
I7V34_RS03695	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
I7V34_RS03700	COG1349	DNA-binding transcription factor activity
I7V34_RS03705	COG0416	fatty acid biosynthetic process
I7V34_RS03710	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
I7V34_RS03715	COG1028	Short-chain dehydrogenase reductase Sdr
I7V34_RS03720	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I7V34_RS03725	COG0571	ribonuclease III activity
I7V34_RS03730	COG1196	nuclear chromosome segregation
I7V34_RS03735	COG0552	protein localization to endoplasmic reticulum
I7V34_RS03740	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
I7V34_RS03745	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
I7V34_RS03750	COG0228	four-way junction DNA binding
I7V34_RS03755	COG1837	Belongs to the UPF0109 family
I7V34_RS03765	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
I7V34_RS03770	COG0336	Belongs to the RNA methyltransferase TrmD family
I7V34_RS03775	COG0335	large ribosomal subunit rRNA binding
I7V34_RS03785	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
I7V34_RS03800	COG2257	FlhB HrpN YscU SpaS Family
I7V34_RS03810	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
I7V34_RS03815	COG0758	DNA mediated transformation
I7V34_RS03820	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
I7V34_RS03825	COG4974	Belongs to the 'phage' integrase family
I7V34_RS03830	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
I7V34_RS03840	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
I7V34_RS03845	COG1815	bacterial-type flagellum-dependent cell motility
I7V34_RS03850	COG1558	bacterial-type flagellum-dependent cell motility
I7V34_RS03855	COG1677	Flagellar hook-basal body complex protein FliE
I7V34_RS03860	COG1766	The M ring may be actively involved in energy transduction
I7V34_RS03865	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
I7V34_RS03875	COG1157	protein secretion by the type III secretion system
I7V34_RS03880	COG2882	bacterial-type flagellum organization
I7V34_RS03895	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
I7V34_RS03910	COG1582	Flagellar protein (FlbD)
I7V34_RS03915	COG1580	Controls the rotational direction of flagella during chemotaxis
I7V34_RS03920	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
I7V34_RS03925	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
I7V34_RS03925	COG1776	CheC inhibitor of MCP methylation
I7V34_RS03930	COG2201	protein-glutamate methylesterase activity
I7V34_RS03935	COG3190	flagellar
I7V34_RS03940	COG1338	Plays a role in the flagellum-specific transport system
I7V34_RS03945	COG1987	bacterial-type flagellum assembly
I7V34_RS03950	COG1684	flagellar biosynthetic protein fliR
I7V34_RS03955	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
I7V34_RS03960	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
I7V34_RS03965	COG1419	protein localization to endoplasmic reticulum
I7V34_RS03970	COG0455	bacterial-type flagellum organization
I7V34_RS03975	COG2201	protein-glutamate methylesterase activity
I7V34_RS03980	COG0643	Histidine kinase
I7V34_RS03980	COG2198	Histidine kinase
I7V34_RS03985	COG0835	chemotaxis
I7V34_RS03990	COG1776	CheC inhibitor of MCP methylation
I7V34_RS03995	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
I7V34_RS04000	COG1191	sigma factor activity
I7V34_RS04010	COG0052	Belongs to the universal ribosomal protein uS2 family
I7V34_RS04015	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
I7V34_RS04030	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
I7V34_RS04035	COG4589	Belongs to the CDS family
I7V34_RS04040	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
I7V34_RS04045	COG0750	zinc metalloprotease
I7V34_RS04050	COG0442	prolyl-tRNA aminoacylation
I7V34_RS04055	COG2176	DNA-directed DNA polymerase activity
I7V34_RS04060	COG0779	Required for maturation of 30S ribosomal subunits
I7V34_RS04065	COG0195	Participates in both transcription termination and antitermination
I7V34_RS04070	COG2740	Nucleic-acid-binding protein implicated in transcription termination
I7V34_RS04075	COG1358	cellular component organization or biogenesis
I7V34_RS04085	COG1550	Protein conserved in bacteria
I7V34_RS04090	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
I7V34_RS04095	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
I7V34_RS04100	COG0196	riboflavin kinase activity
I7V34_RS04110	COG1185	polyribonucleotide nucleotidyltransferase activity
I7V34_RS04115	COG0726	polysaccharide deacetylase
I7V34_RS04120	COG0612	Peptidase, M16
I7V34_RS04125	COG1873	PFAM PRC-barrel domain
I7V34_RS04130	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
I7V34_RS04135	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
I7V34_RS04140	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
I7V34_RS04145	COG0527	aspartate kinase activity
I7V34_RS04155	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
I7V34_RS04160	COG0740	serine-type endopeptidase activity
I7V34_RS04170	COG4980	gas vesicle protein
I7V34_RS04170	COG1674	ftsk spoiiie
I7V34_RS04175	COG2188	Transcriptional regulator
I7V34_RS04180	COG1744	ABC transporter substrate-binding protein PnrA-like
I7V34_RS04185	COG3845	ABC transporter
I7V34_RS04190	COG4603	Belongs to the binding-protein-dependent transport system permease family
I7V34_RS04195	COG1079	Belongs to the binding-protein-dependent transport system permease family
I7V34_RS04200	COG0612	Peptidase, M16
I7V34_RS04205	COG0612	Peptidase, M16
I7V34_RS04210	COG0300	oxidoreductase activity
I7V34_RS04225	COG1426	Protein conserved in bacteria
I7V34_RS04230	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
I7V34_RS04235	COG1058	Belongs to the CinA family
I7V34_RS04235	COG1546	Belongs to the CinA family
I7V34_RS04250	COG1692	metallophosphoesterase
I7V34_RS04255	COG2359	stage V sporulation protein S
I7V34_RS04265	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
I7V34_RS04265	COG0674	pyruvate-flavodoxin oxidoreductase activity
I7V34_RS04270	COG1013	pyruvate-flavodoxin oxidoreductase activity
I7V34_RS04280	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
I7V34_RS04285	COG4550	Control of competence regulator ComK, YlbF/YmcA
I7V34_RS04300	COG0551	DNA topoisomerase type I activity
I7V34_RS04300	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
I7V34_RS04310	COG1966	Carbon starvation protein
I7V34_RS04320	COG0493	'glutamate synthase
I7V34_RS04350	COG2508	Transcriptional regulator
I7V34_RS04355	COG1012	belongs to the aldehyde dehydrogenase family
I7V34_RS04360	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
I7V34_RS04370	COG2720	vancomycin resistance protein
I7V34_RS04385	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
I7V34_RS04390	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
I7V34_RS04395	COG0277	FAD linked oxidase domain protein
I7V34_RS04400	COG2271	Major facilitator Superfamily
I7V34_RS04410	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
I7V34_RS04415	COG1923	regulation of RNA biosynthetic process
I7V34_RS04420	COG0464	growth
I7V34_RS04425	COG2860	membrane
I7V34_RS04430	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
I7V34_RS04435	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
I7V34_RS04440	COG0789	Transcriptional regulator
I7V34_RS04445	COG0174	glutamine synthetase
I7V34_RS04450	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
I7V34_RS04460	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
I7V34_RS04465	COG4224	UPF0291 protein
I7V34_RS04480	COG3763	UPF0154 protein
I7V34_RS04490	COG1132	(ABC) transporter
I7V34_RS04495	COG1132	(ABC) transporter
I7V34_RS04505	COG0785	Cytochrome C biogenesis protein
I7V34_RS04510	COG2201	protein-glutamate methylesterase activity
I7V34_RS04515	COG4846	Membrane protein involved in cytochrome C biogenesis
I7V34_RS04520	COG1994	Peptidase M50
I7V34_RS04530	COG3852	Histidine kinase
I7V34_RS04555	COG0419	ATPase involved in DNA repair
I7V34_RS04580	COG5146	pantothenate kinase activity
I7V34_RS04585	COG1999	signal sequence binding
I7V34_RS04605	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
I7V34_RS04620	COG1063	alcohol dehydrogenase
I7V34_RS04625	COG0626	cystathionine gamma-synthase activity
I7V34_RS04630	COG0626	cystathionine gamma-synthase activity
I7V34_RS04635	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
I7V34_RS04635	COG0646	methionine synthase
I7V34_RS04640	COG1410	methionine synthase
I7V34_RS04640	COG0646	methionine synthase
I7V34_RS04650	COG1366	Belongs to the anti-sigma-factor antagonist family
I7V34_RS04655	COG0346	lactoylglutathione lyase activity
I7V34_RS04660	COG0400	carboxylic ester hydrolase activity
I7V34_RS04670	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
I7V34_RS04690	COG2267	carboxylic ester hydrolase activity
I7V34_RS04700	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
I7V34_RS04710	COG1368	sulfuric ester hydrolase activity
I7V34_RS04715	COG2205	protein histidine kinase activity
I7V34_RS04720	COG0697	spore germination
I7V34_RS04745	COG1183	phosphatidylcholine synthase activity
I7V34_RS04775	COG0659	secondary active sulfate transmembrane transporter activity
I7V34_RS04810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
I7V34_RS04815	COG5566	PFAM Mor transcription activator
I7V34_RS04825	COG0820	rRNA (adenine-C2-)-methyltransferase activity
I7V34_RS04835	COG0546	phosphoglycolate phosphatase activity
I7V34_RS04860	COG0456	acetyltransferase
I7V34_RS04870	COG1595	DNA-templated transcription, initiation
I7V34_RS04880	COG1125	glycine betaine transport
I7V34_RS04880	COG0517	IMP dehydrogenase activity
I7V34_RS04885	COG1174	glycine betaine transport
I7V34_RS04900	COG1597	lipid kinase activity
I7V34_RS04910	COG0110	maltose O-acetyltransferase activity
I7V34_RS04920	COG2239	Acts as a magnesium transporter
I7V34_RS04930	COG0860	N-Acetylmuramoyl-L-alanine amidase
I7V34_RS04940	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
I7V34_RS04950	COG1834	amidinotransferase
I7V34_RS04955	COG1113	amino acid transport
I7V34_RS04960	COG2814	Major facilitator Superfamily
I7V34_RS04965	COG1253	flavin adenine dinucleotide binding
I7V34_RS04970	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
I7V34_RS04975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
I7V34_RS04980	COG0588	phosphoglycerate mutase activity
I7V34_RS04990	COG1247	-acetyltransferase
I7V34_RS05000	COG2202	Pas domain
I7V34_RS05000	COG1366	Belongs to the anti-sigma-factor antagonist family
I7V34_RS05020	COG1366	Belongs to the anti-sigma-factor antagonist family
I7V34_RS05035	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
I7V34_RS05050	COG2124	cytochrome p450
I7V34_RS05060	COG1960	acyl-CoA dehydrogenase activity
I7V34_RS05070	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
I7V34_RS05075	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
I7V34_RS05080	COG1742	UPF0060 membrane protein
I7V34_RS05085	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
I7V34_RS05090	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
I7V34_RS05095	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
I7V34_RS05095	COG1918	ferrous iron import across plasma membrane
I7V34_RS05110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
I7V34_RS05140	COG1660	Displays ATPase and GTPase activities
I7V34_RS05145	COG4326	sporulation control protein
I7V34_RS05175	COG1309	transcriptional regulator
I7V34_RS05180	COG2814	Major facilitator Superfamily
I7V34_RS05185	COG0477	Major facilitator Superfamily
I7V34_RS05195	COG2226	methyltransferase
I7V34_RS05200	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
I7V34_RS05205	COG4122	O-methyltransferase activity
I7V34_RS05210	COG0702	epimerase
I7V34_RS05215	COG1366	Belongs to the anti-sigma-factor antagonist family
I7V34_RS05220	COG2340	Cysteine-rich secretory protein family
I7V34_RS05230	COG1011	Hydrolase
I7V34_RS05245	COG0500	methyltransferase
I7V34_RS05255	COG0768	penicillin binding
I7V34_RS05265	COG2217	Heavy metal translocating P-type atpase
I7V34_RS05290	COG1619	proteins homologs of microcin C7 resistance protein MccF
I7V34_RS05300	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
I7V34_RS05315	COG2309	aminopeptidase activity
I7V34_RS05335	COG1349	DNA-binding transcription factor activity
I7V34_RS05340	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
I7V34_RS05345	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
I7V34_RS05350	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
I7V34_RS05355	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
I7V34_RS05365	COG1028	Short-chain dehydrogenase reductase Sdr
I7V34_RS05380	COG0006	proline dipeptidase activity
I7V34_RS05390	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
I7V34_RS05395	COG4191	Histidine kinase
I7V34_RS05405	COG1380	Effector of murein hydrolase LrgA
I7V34_RS05410	COG1346	cytolysis
I7V34_RS05415	COG0024	Methionine aminopeptidase
I7V34_RS05425	COG3584	3D domain protein
I7V34_RS05425	COG1388	LysM domain
I7V34_RS05430	COG1388	LysM domain
I7V34_RS05430	COG3584	3D domain protein
I7V34_RS05435	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
I7V34_RS05450	COG0840	transmembrane signaling receptor activity
I7V34_RS05495	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
I7V34_RS05500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I7V34_RS05520	COG0824	Thioesterase
I7V34_RS05530	COG4841	protein insertion into membrane
I7V34_RS05545	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
I7V34_RS05550	COG2233	PERMEase
I7V34_RS05555	COG1125	glycine betaine transport
I7V34_RS05555	COG0517	IMP dehydrogenase activity
I7V34_RS05560	COG1174	glycine betaine transport
I7V34_RS05565	COG1732	Glycine betaine
I7V34_RS05570	COG1832	CoA-binding protein
I7V34_RS05575	COG0187	DNA topoisomerase II activity
I7V34_RS05580	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
I7V34_RS05585	COG1115	amino acid carrier protein
I7V34_RS05660	COG4608	Belongs to the ABC transporter superfamily
I7V34_RS05665	COG0791	NLP P60 protein
I7V34_RS05670	COG4948	Mandelate Racemase Muconate Lactonizing
I7V34_RS05675	COG1619	proteins homologs of microcin C7 resistance protein MccF
I7V34_RS05680	COG4166	transmembrane transport
I7V34_RS05685	COG0444	Belongs to the ABC transporter superfamily
I7V34_RS05690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
I7V34_RS05695	COG0601	transmembrane transport
I7V34_RS05700	COG2362	D-Aminopeptidase
I7V34_RS05705	COG2233	PERMEase
I7V34_RS05710	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
I7V34_RS05715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I7V34_RS05715	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
I7V34_RS05725	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
I7V34_RS05730	COG2022	thiamine diphosphate biosynthetic process
I7V34_RS05740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
I7V34_RS05745	COG0352	thiamine-phosphate diphosphorylase activity
I7V34_RS05755	COG4172	Belongs to the ABC transporter superfamily
I7V34_RS05765	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
I7V34_RS05770	COG2197	response regulator
I7V34_RS05775	COG4585	Histidine kinase
I7V34_RS05800	COG0708	Exodeoxyribonuclease III
I7V34_RS05825	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
I7V34_RS05840	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
I7V34_RS05860	COG1011	Hydrolase
I7V34_RS05875	COG3493	citrate carrier protein
I7V34_RS05880	COG4565	transcriptional regulatory protein
I7V34_RS05885	COG3290	protein histidine kinase activity
I7V34_RS05900	COG0745	RESPONSE REGULATOR receiver
I7V34_RS05905	COG5002	protein histidine kinase activity
I7V34_RS05910	COG1999	signal sequence binding
I7V34_RS05915	COG0450	alkyl hydroperoxide reductase
I7V34_RS05940	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
I7V34_RS05950	COG0352	thiamine-phosphate diphosphorylase activity
I7V34_RS05955	COG0351	phosphomethylpyrimidine kinase
I7V34_RS05960	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
I7V34_RS05970	COG1620	l-lactate permease
I7V34_RS05975	COG1414	Transcriptional regulator
I7V34_RS05985	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
I7V34_RS05990	COG0277	FAD linked oxidase domain protein
I7V34_RS05995	COG0247	lactate metabolic process
I7V34_RS06000	COG0277	FAD linked oxidase domain protein
I7V34_RS06005	COG2186	Transcriptional regulator
I7V34_RS06015	COG5632	N-Acetylmuramoyl-L-alanine amidase
I7V34_RS06065	COG0456	acetyltransferase
I7V34_RS06095	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
I7V34_RS06115	COG0300	oxidoreductase activity
I7V34_RS06150	COG2814	Major facilitator Superfamily
I7V34_RS06170	COG1131	(ABC) transporter
I7V34_RS06175	COG1309	transcriptional regulator
I7V34_RS06185	COG1162	GTPase activity
I7V34_RS06200	COG3620	sequence-specific DNA binding
I7V34_RS06220	COG1511	domain protein
I7V34_RS06220	COG0842	Transport permease protein
I7V34_RS06225	COG1131	(ABC) transporter
I7V34_RS06240	COG0488	(ABC) transporter
I7V34_RS06245	COG0662	Cupin 2, conserved barrel domain protein
I7V34_RS06250	COG2205	protein histidine kinase activity
I7V34_RS06280	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
I7V34_RS06290	COG0693	protein deglycase activity
I7V34_RS06330	COG1879	ABC-type sugar transport system periplasmic component
I7V34_RS06335	COG1172	Belongs to the binding-protein-dependent transport system permease family
I7V34_RS06340	COG1129	ABC transporter
I7V34_RS06345	COG1869	D-ribose catabolic process
I7V34_RS06350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I7V34_RS06355	COG1609	Transcriptional regulator
I7V34_RS06360	COG0860	N-Acetylmuramoyl-L-alanine amidase
I7V34_RS06365	COG1595	DNA-templated transcription, initiation
I7V34_RS06390	COG2205	protein histidine kinase activity
I7V34_RS06395	COG0745	RESPONSE REGULATOR receiver
I7V34_RS06420	COG2153	protein acetylation
I7V34_RS06430	COG1959	2 iron, 2 sulfur cluster binding
I7V34_RS06435	COG1393	Belongs to the ArsC family
I7V34_RS06440	COG0456	acetyltransferase
I7V34_RS06480	COG2211	Major facilitator Superfamily
I7V34_RS06490	COG3850	Histidine kinase
I7V34_RS06490	COG5002	protein histidine kinase activity
I7V34_RS06495	COG0745	RESPONSE REGULATOR receiver
I7V34_RS06505	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
I7V34_RS06510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
I7V34_RS06565	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
I7V34_RS06570	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
I7V34_RS06580	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
I7V34_RS06590	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
I7V34_RS06595	COG2304	oxidoreductase activity
I7V34_RS06620	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
I7V34_RS06630	COG1335	isochorismatase
I7V34_RS06705	COG3340	Belongs to the peptidase S51 family
I7V34_RS06725	COG3852	Histidine kinase
I7V34_RS06770	COG1051	belongs to the nudix hydrolase family
I7V34_RS06780	COG0124	histidyl-tRNA synthetase
I7V34_RS06790	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
I7V34_RS06795	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
I7V34_RS06800	COG2323	membrane
I7V34_RS06810	COG0028	Belongs to the TPP enzyme family
I7V34_RS06815	COG2070	2-Nitropropane dioxygenase
I7V34_RS06895	COG0778	Nitroreductase
I7V34_RS06905	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
I7V34_RS06910	COG0561	phosphatase activity
I7V34_RS06940	COG0592	DNA-directed DNA polymerase activity
I7V34_RS06985	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
I7V34_RS06985	COG3711	transcriptional antiterminator
I7V34_RS07005	COG0456	acetyltransferase
I7V34_RS07015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I7V34_RS07100	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
I7V34_RS07105	COG1349	DNA-binding transcription factor activity
I7V34_RS07110	COG3842	ATPase activity
I7V34_RS07120	COG0395	ABC-type sugar transport system, permease component
I7V34_RS07190	COG2323	membrane
I7V34_RS07215	COG0590	tRNA wobble adenosine to inosine editing
I7V34_RS07220	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
I7V34_RS07240	COG1522	sequence-specific DNA binding
I7V34_RS07245	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
I7V34_RS07260	COG0640	Transcriptional regulator
I7V34_RS07270	COG2226	methyltransferase
I7V34_RS07320	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
I7V34_RS07345	COG1051	belongs to the nudix hydrolase family
I7V34_RS07355	COG2226	methyltransferase
I7V34_RS07360	COG3227	Zinc metalloprotease (Elastase)
I7V34_RS07385	COG1028	Short-chain dehydrogenase reductase Sdr
I7V34_RS07395	COG5002	protein histidine kinase activity
I7V34_RS07395	COG3850	Histidine kinase
I7V34_RS07400	COG0745	RESPONSE REGULATOR receiver
I7V34_RS07410	COG4086	secreted protein
I7V34_RS07415	COG4191	Histidine kinase
I7V34_RS07420	COG0730	response to heat
I7V34_RS07425	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
I7V34_RS07425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I7V34_RS07430	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
I7V34_RS07430	COG0425	Belongs to the sulfur carrier protein TusA family
I7V34_RS07435	COG2210	Belongs to the sulfur carrier protein TusA family
I7V34_RS07440	COG0425	Belongs to the sulfur carrier protein TusA family
I7V34_RS07445	COG1937	Protein conserved in bacteria
I7V34_RS07450	COG0003	Pfam Anion-transporting ATPase
I7V34_RS07460	COG1966	Carbon starvation protein
I7V34_RS07475	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
I7V34_RS07485	COG2323	membrane
I7V34_RS07490	COG2309	aminopeptidase activity
I7V34_RS07500	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
I7V34_RS07510	COG0517	IMP dehydrogenase activity
I7V34_RS07510	COG0516	GMP reductase activity
I7V34_RS07515	COG2176	DNA-directed DNA polymerase activity
I7V34_RS07520	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
I7V34_RS07525	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
I7V34_RS07530	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
I7V34_RS07555	COG1120	ATPase activity
I7V34_RS07560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I7V34_RS07565	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
I7V34_RS07570	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
I7V34_RS07585	COG2996	Protein conserved in bacteria
I7V34_RS07590	COG2223	nitrite transmembrane transporter activity
I7V34_RS07610	COG0488	(ABC) transporter
I7V34_RS07615	COG0514	ATP-dependent DNA helicase (RecQ)
I7V34_RS07650	COG1686	Belongs to the peptidase S11 family
I7V34_RS07660	COG3853	Toxic anion resistance protein (TelA)
I7V34_RS07670	COG4548	von Willebrand factor, type A
I7V34_RS07675	COG0714	Associated with various cellular activities
I7V34_RS07695	COG0586	Pfam SNARE associated Golgi protein
I7V34_RS07700	COG2105	PFAM AIG2 family protein
I7V34_RS07705	COG0318	PFAM AMP-dependent synthetase and ligase
I7V34_RS07715	COG0508	dehydrogenase complex catalyzes the overall conversion of
I7V34_RS07720	COG0567	Dehydrogenase, E1 component
I7V34_RS07730	COG5002	protein histidine kinase activity
I7V34_RS07740	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
I7V34_RS07745	COG0432	Pfam Uncharacterised protein family UPF0047
I7V34_RS07750	COG3011	Protein conserved in bacteria
I7V34_RS07755	COG0406	alpha-ribazole phosphatase activity
I7V34_RS07800	COG2076	Multidrug Resistance protein
I7V34_RS07820	COG0697	spore germination
I7V34_RS07825	COG3541	Predicted nucleotidyltransferase
I7V34_RS07830	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
I7V34_RS07845	COG1278	Cold shock
I7V34_RS07860	COG0494	nUDIX hydrolase
I7V34_RS07885	COG2226	methyltransferase
I7V34_RS07890	COG0446	pyridine nucleotide-disulphide oxidoreductase
I7V34_RS07910	COG0134	indole-3-glycerol-phosphate synthase activity
I7V34_RS07915	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
I7V34_RS07920	COG0512	Glutamine amidotransferase of anthranilate synthase
I7V34_RS07935	COG4145	pantothenate transmembrane transporter activity
I7V34_RS07945	COG5522	Integral membrane protein (intg_mem_TP0381)
I7V34_RS07955	COG0671	phosphoesterase, PA-phosphatase related
I7V34_RS07960	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
I7V34_RS07965	COG1793	dna ligase
I7V34_RS07965	COG3285	dna ligase
I7V34_RS07980	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
I7V34_RS07990	COG1942	4-Oxalocrotonate Tautomerase
I7V34_RS07995	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
I7V34_RS08005	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
I7V34_RS08030	COG1012	belongs to the aldehyde dehydrogenase family
I7V34_RS08035	COG0251	oxidation-reduction process
I7V34_RS08050	COG0431	NADPH-dependent FMN reductase
I7V34_RS08055	COG0196	riboflavin kinase activity
I7V34_RS08060	COG2368	4-hydroxyphenylacetate
I7V34_RS08070	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
I7V34_RS08080	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
I7V34_RS08080	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
I7V34_RS08085	COG0307	riboflavin synthase, alpha
I7V34_RS08090	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
I7V34_RS08090	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
I7V34_RS08105	COG4667	esterase of the alpha-beta hydrolase superfamily
I7V34_RS08110	COG0494	nUDIX hydrolase
I7V34_RS08115	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
I7V34_RS08120	COG1131	(ABC) transporter
I7V34_RS08145	COG0586	Pfam SNARE associated Golgi protein
I7V34_RS08150	COG1228	amidohydrolase
I7V34_RS08170	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
I7V34_RS08175	COG0534	Mate efflux family protein
I7V34_RS08180	COG1028	Short-chain dehydrogenase reductase Sdr
I7V34_RS08185	COG2340	Cysteine-rich secretory protein family
I7V34_RS08205	COG0523	cobalamin synthesis protein
I7V34_RS08220	COG0793	Belongs to the peptidase S41A family
I7V34_RS08220	COG3409	Peptidoglycan-binding domain 1 protein
I7V34_RS08230	COG1876	peptidase activity
I7V34_RS08250	COG4326	sporulation control protein
I7V34_RS08270	COG4479	Belongs to the UPF0346 family
I7V34_RS08280	COG1509	lysine 2,3-aminomutase activity
I7V34_RS08285	COG0456	acetyltransferase
I7V34_RS08290	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
I7V34_RS08295	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
I7V34_RS08300	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
I7V34_RS08305	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
I7V34_RS08310	COG5278	phosphoserine phosphatase activity
I7V34_RS08310	COG0840	transmembrane signaling receptor activity
I7V34_RS08325	COG2190	(PTS) system
I7V34_RS08330	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
I7V34_RS08335	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
I7V34_RS08355	COG2755	lipolytic protein G-D-S-L family
I7V34_RS08360	COG1307	EDD domain protein, DegV family
I7V34_RS08370	COG2135	peptidase activity
I7V34_RS08375	COG1272	protein, Hemolysin III
I7V34_RS08380	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
I7V34_RS08400	COG2136	Putative SAM-dependent methyltransferase
I7V34_RS08400	COG2521	methyltransferase
I7V34_RS08410	COG1413	lyase activity
I7V34_RS08415	COG0488	(ABC) transporter
I7V34_RS08420	COG1418	mRNA catabolic process
I7V34_RS08425	COG1307	EDD domain protein, DegV family
I7V34_RS08450	COG1321	iron dependent repressor
I7V34_RS08455	COG1278	Cold shock
I7V34_RS08465	COG0328	RNA-DNA hybrid ribonuclease activity
I7V34_RS08470	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
I7V34_RS08475	COG0328	RNA-DNA hybrid ribonuclease activity
I7V34_RS08495	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
I7V34_RS08500	COG2897	thiosulfate sulfurtransferase activity
I7V34_RS08510	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
I7V34_RS08520	COG3424	synthase
I7V34_RS08525	COG1406	Chemotaxis phosphatase CheX
I7V34_RS08530	COG1028	Short-chain dehydrogenase reductase Sdr
I7V34_RS08540	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
I7V34_RS08545	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
I7V34_RS08550	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
I7V34_RS08570	COG1199	ATP-dependent helicase activity
I7V34_RS08580	COG0116	Belongs to the methyltransferase superfamily
I7V34_RS08590	COG3599	regulation of cell shape
I7V34_RS08595	COG4474	Belongs to the UPF0398 family
I7V34_RS08605	COG3359	exonuclease
I7V34_RS08610	COG1205	dead DEAH box helicase
I7V34_RS08610	COG1111	helicase
I7V34_RS08620	COG0071	Belongs to the small heat shock protein (HSP20) family
I7V34_RS08655	COG4499	WXG100 protein secretion system (Wss), protein YukC
I7V34_RS08655	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
I7V34_RS08665	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
I7V34_RS08670	COG3935	DnaD domain protein
I7V34_RS08675	COG0017	Asparaginyl-tRNA synthetase
I7V34_RS08680	COG0436	Aminotransferase
I7V34_RS08700	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
I7V34_RS08700	COG1199	ATP-dependent helicase activity
I7V34_RS08705	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
I7V34_RS08710	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
I7V34_RS08715	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
I7V34_RS08730	COG0438	transferase activity, transferring glycosyl groups
I7V34_RS08735	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
I7V34_RS08740	COG1803	Methylglyoxal synthase
I7V34_RS08750	COG1694	Mazg nucleotide pyrophosphohydrolase
I7V34_RS08755	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
I7V34_RS08760	COG2738	Putative neutral zinc metallopeptidase
I7V34_RS08770	COG4347	Protein of unknown function (DUF1405)
I7V34_RS08780	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
I7V34_RS08800	COG0457	Tetratricopeptide repeat
I7V34_RS08810	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
I7V34_RS08815	COG0287	Prephenate dehydrogenase
I7V34_RS08820	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
I7V34_RS08825	COG4401	Chorismate mutase type I
I7V34_RS08830	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
I7V34_RS08835	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
I7V34_RS08840	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
I7V34_RS08845	COG0105	UTP biosynthetic process
I7V34_RS08850	COG0142	geranyltranstransferase activity
I7V34_RS08855	COG2226	methyltransferase
I7V34_RS08860	COG0142	geranyltranstransferase activity
I7V34_RS08870	COG0302	gtp cyclohydrolase
I7V34_RS08875	COG0776	regulation of translation
I7V34_RS08880	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
I7V34_RS08895	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
I7V34_RS08900	COG1160	GTP binding
I7V34_RS08930	COG0539	negative regulation of cytoplasmic translation
I7V34_RS08935	COG0204	Acyl-transferase
I7V34_RS08940	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
I7V34_RS08955	COG2959	enzyme of heme biosynthesis
I7V34_RS08960	COG3773	Cell wall hydrolase
I7V34_RS08960	COG3409	Peptidoglycan-binding domain 1 protein
I7V34_RS08970	COG2339	peptidase activity
I7V34_RS08980	COG0492	ferredoxin-NADP+ reductase activity
I7V34_RS08985	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
I7V34_RS08990	COG4862	establishment of competence for transformation
I7V34_RS08995	COG0789	Transcriptional regulator
I7V34_RS09000	COG1408	metallophosphoesterase
I7V34_RS09025	COG3546	catalase activity
I7V34_RS09035	COG1388	LysM domain
I7V34_RS09040	COG1266	CAAX protease self-immunity
I7V34_RS09045	COG0514	ATP-dependent DNA helicase (RecQ)
I7V34_RS09050	COG4955	Helix-turn-helix domain
I7V34_RS09055	COG1141	Ferredoxin
I7V34_RS09060	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
I7V34_RS09065	COG0739	heme binding
I7V34_RS09075	COG1595	DNA-templated transcription, initiation
I7V34_RS09080	COG5002	protein histidine kinase activity
I7V34_RS09085	COG0745	RESPONSE REGULATOR receiver
I7V34_RS09090	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
I7V34_RS09095	COG1333	cytochrome c biogenesis protein
I7V34_RS09100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I7V34_RS09105	COG1187	pseudouridine synthase activity
I7V34_RS09115	COG0700	Nucleoside recognition
I7V34_RS09120	COG2715	membrane protein required for spore maturation
I7V34_RS09125	COG1686	Belongs to the peptidase S11 family
I7V34_RS09130	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
I7V34_RS09135	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
I7V34_RS09140	COG1547	Domain of unknown function (DUF309)
I7V34_RS09155	COG0697	spore germination
I7V34_RS09190	COG1686	Belongs to the peptidase S11 family
I7V34_RS09205	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
I7V34_RS09210	COG4974	Belongs to the 'phage' integrase family
I7V34_RS09220	COG0735	belongs to the Fur family
I7V34_RS09225	COG1300	Membrane
I7V34_RS09240	COG0667	Aldo Keto reductase
I7V34_RS09250	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
I7V34_RS09255	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
I7V34_RS09260	COG0183	Belongs to the thiolase family
I7V34_RS09265	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
I7V34_RS09270	COG1073	alpha beta
I7V34_RS09280	COG4918	Iron-sulphur cluster biosynthesis
I7V34_RS09295	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
I7V34_RS09305	COG4975	Glucose uptake
I7V34_RS09315	COG0300	oxidoreductase activity
I7V34_RS09320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I7V34_RS09325	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
I7V34_RS09330	COG1902	pentaerythritol trinitrate reductase activity
I7V34_RS09340	COG1234	tRNA 3'-trailer cleavage
I7V34_RS09345	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
I7V34_RS09350	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
I7V34_RS09365	COG2195	Cleaves the N-terminal amino acid of tripeptides
I7V34_RS09370	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
I7V34_RS09375	COG0346	lactoylglutathione lyase activity
I7V34_RS09385	COG1376	ErfK ybiS ycfS ynhG family protein
I7V34_RS09390	COG4129	membrane
I7V34_RS09395	COG1126	abc transporter atp-binding protein
I7V34_RS09400	COG0765	amino acid transport
I7V34_RS09405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I7V34_RS09420	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
I7V34_RS09420	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
I7V34_RS09425	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
I7V34_RS09430	COG1404	Belongs to the peptidase S8 family
I7V34_RS09430	COG4412	M6 family metalloprotease domain protein
I7V34_RS09435	COG0508	dehydrogenase complex catalyzes the overall conversion of
I7V34_RS09440	COG0022	dehydrogenase e1 component
I7V34_RS09445	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
I7V34_RS09450	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
I7V34_RS09460	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
I7V34_RS09465	COG0280	phosphate acetyltransferase
I7V34_RS09470	COG3829	transcription factor binding
I7V34_RS09470	COG3290	protein histidine kinase activity
I7V34_RS09480	COG0584	glycerophosphoryl diester phosphodiesterase
I7V34_RS09490	COG0750	zinc metalloprotease
I7V34_RS09495	COG0497	DNA recombination
I7V34_RS09505	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
I7V34_RS09510	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
I7V34_RS09530	COG1570	exodeoxyribonuclease VII activity
I7V34_RS09535	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
I7V34_RS09540	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
I7V34_RS09545	COG1302	Protein conserved in bacteria
I7V34_RS09550	COG0439	Biotin carboxylase
I7V34_RS09555	COG0511	ligase activity, forming carbon-carbon bonds
I7V34_RS09595	COG3854	ATPases associated with a variety of cellular activities
I7V34_RS09600	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
I7V34_RS09605	COG0006	proline dipeptidase activity
I7V34_RS09625	COG1752	Esterase of the alpha-beta hydrolase superfamily
I7V34_RS09630	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
I7V34_RS09640	COG0095	Lipoate-protein ligase
I7V34_RS09645	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
I7V34_RS09650	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
I7V34_RS09655	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
I7V34_RS09660	COG0404	The glycine cleavage system catalyzes the degradation of glycine
I7V34_RS09665	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
I7V34_RS09705	COG4537	Required for transformation and DNA binding
I7V34_RS09715	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
I7V34_RS09725	COG1393	Belongs to the ArsC family
I7V34_RS09735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I7V34_RS09745	COG0011	TIGRFAM Protein of
I7V34_RS09760	COG1368	sulfuric ester hydrolase activity
I7V34_RS09765	COG1940	carbohydrate kinase activity
I7V34_RS09775	COG0697	spore germination
I7V34_RS09785	COG0457	Tetratricopeptide repeat
I7V34_RS09785	COG0705	Rhomboid family
I7V34_RS09800	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
I7V34_RS09805	COG0267	Belongs to the bacterial ribosomal protein bL33 family
I7V34_RS09815	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
I7V34_RS09840	COG0840	transmembrane signaling receptor activity
I7V34_RS09845	COG0704	Plays a role in the regulation of phosphate uptake
I7V34_RS09850	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
I7V34_RS09855	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
I7V34_RS09860	COG0581	inorganic phosphate transmembrane transporter activity
I7V34_RS09865	COG0573	inorganic phosphate transmembrane transporter activity
I7V34_RS09870	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
I7V34_RS09875	COG0768	penicillin binding
I7V34_RS09880	COG0477	Major facilitator Superfamily
I7V34_RS09890	COG2839	Protein conserved in bacteria
I7V34_RS09895	COG1283	sodium-dependent phosphate transmembrane transporter activity
I7V34_RS09900	COG2814	Major facilitator Superfamily
I7V34_RS09910	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
I7V34_RS09915	COG4709	membrane
I7V34_RS09920	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
I7V34_RS09925	COG0735	belongs to the Fur family
I7V34_RS09930	COG1108	ABC-type Mn2 Zn2 transport systems permease components
I7V34_RS09935	COG1121	(ABC) transporter
I7V34_RS09945	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
I7V34_RS09950	COG0513	Belongs to the DEAD box helicase family
I7V34_RS09960	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
I7V34_RS09965	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
I7V34_RS09970	COG2384	SAM-dependent methyltransferase
I7V34_RS09975	COG2010	Cytochrome c
I7V34_RS09980	COG1960	acyl-CoA dehydrogenase activity
I7V34_RS09990	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
I7V34_RS09995	COG0358	DNA primase activity
I7V34_RS10000	COG1671	Belongs to the UPF0178 family
I7V34_RS10010	COG0517	IMP dehydrogenase activity
I7V34_RS10020	COG1381	Involved in DNA repair and RecF pathway recombination
I7V34_RS10035	COG0295	cytidine deaminase activity
I7V34_RS10045	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
I7V34_RS10050	COG1480	7TM receptor with intracellular HD hydrolase
I7V34_RS10055	COG1702	phosphate starvation-inducible protein PhoH
I7V34_RS10075	COG4864	UPF0365 protein
I7V34_RS10080	COG1030	water channel activity
I7V34_RS10085	COG1610	YqeY-like protein
I7V34_RS10095	COG1283	sodium-dependent phosphate transmembrane transporter activity
I7V34_RS10105	COG0366	Alpha amylase catalytic
I7V34_RS10110	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
I7V34_RS10115	COG1385	rRNA (uridine-N3-)-methyltransferase activity
I7V34_RS10125	COG0484	heat shock protein binding
I7V34_RS10130	COG0443	Heat shock 70 kDa protein
I7V34_RS10135	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
I7V34_RS10140	COG1420	regulation of RNA biosynthetic process
I7V34_RS10145	COG0635	Involved in the biosynthesis of porphyrin-containing compound
I7V34_RS10150	COG0481	GTPase activity
I7V34_RS10160	COG0860	N-Acetylmuramoyl-L-alanine amidase
I7V34_RS10170	COG0268	Binds directly to 16S ribosomal RNA
I7V34_RS10175	COG1466	dna polymerase III delta subunit
I7V34_RS10185	COG0658	competence protein
I7V34_RS10185	COG2333	competence protein COMEC
I7V34_RS10190	COG2131	deaminase
I7V34_RS10195	COG1596	polysaccharide export
I7V34_RS10195	COG1555	photosystem II stabilization
I7V34_RS10200	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
I7V34_RS10205	COG2226	methyltransferase
I7V34_RS10210	COG0799	negative regulation of ribosome biogenesis
I7V34_RS10215	COG1713	HD superfamily hydrolase involved in NAD metabolism
I7V34_RS10220	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
I7V34_RS10225	COG1534	Rna-binding protein
I7V34_RS10235	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
I7V34_RS10240	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
I7V34_RS10255	COG1183	phosphatidylcholine synthase activity
I7V34_RS10270	COG0640	Transcriptional regulator
I7V34_RS10280	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
I7V34_RS10285	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
I7V34_RS10290	COG0640	Transcriptional regulator
I7V34_RS10315	COG0626	cystathionine gamma-synthase activity
I7V34_RS10320	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
I7V34_RS10325	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
I7V34_RS10330	COG2226	methyltransferase
I7V34_RS10345	COG0768	penicillin binding
I7V34_RS10350	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
I7V34_RS10355	COG0572	uridine kinase
I7V34_RS10360	COG0826	peptidase U32
I7V34_RS10365	COG0826	peptidase U32
I7V34_RS10370	COG4122	O-methyltransferase activity
I7V34_RS10375	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
I7V34_RS10380	COG3906	Belongs to the UPF0473 family
I7V34_RS10385	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
I7V34_RS10390	COG4472	Bacterial protein of unknown function (DUF965)
I7V34_RS10400	COG0628	permease
I7V34_RS10415	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
I7V34_RS10420	COG1268	BioY protein
I7V34_RS10425	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
I7V34_RS10435	COG0482	sulfurtransferase activity
I7V34_RS10440	COG1104	cysteine desulfurase activity
I7V34_RS10445	COG1959	2 iron, 2 sulfur cluster binding
I7V34_RS10450	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
I7V34_RS10460	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
I7V34_RS10465	COG1131	(ABC) transporter
I7V34_RS10470	COG1131	(ABC) transporter
I7V34_RS10475	COG1725	Transcriptional regulator
I7V34_RS10490	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
I7V34_RS10500	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
I7V34_RS10505	COG0124	histidyl-tRNA synthetase
I7V34_RS10515	COG3103	Sh3 type 3 domain protein
I7V34_RS10515	COG4991	sh3 domain protein
I7V34_RS10515	COG0860	N-Acetylmuramoyl-L-alanine amidase
I7V34_RS10520	COG1490	D-aminoacyl-tRNA deacylase activity
I7V34_RS10525	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
I7V34_RS10530	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
I7V34_RS10535	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
I7V34_RS10535	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
I7V34_RS10540	COG5416	Lipopolysaccharide assembly protein A domain
I7V34_RS10545	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
I7V34_RS10550	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
I7V34_RS10550	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
I7V34_RS10560	COG2244	polysaccharide biosynthetic process
I7V34_RS10565	COG2323	membrane
I7V34_RS10570	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
I7V34_RS10580	COG1862	Preprotein translocase
I7V34_RS10590	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
I7V34_RS10625	COG1388	LysM domain
I7V34_RS10630	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
I7V34_RS10635	COG0157	Belongs to the NadC ModD family
I7V34_RS10640	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
I7V34_RS10645	COG1104	cysteine desulfurase activity
I7V34_RS10650	COG1827	regulation of RNA biosynthetic process
I7V34_RS10655	COG0077	Prephenate dehydratase
I7V34_RS10660	COG4492	Belongs to the UPF0735 family
I7V34_RS10665	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
I7V34_RS10670	COG3290	protein histidine kinase activity
I7V34_RS10675	COG0211	Belongs to the bacterial ribosomal protein bL27 family
I7V34_RS10680	COG2868	ribosomal protein
I7V34_RS10685	COG0261	This protein binds to 23S rRNA in the presence of protein L20
I7V34_RS10690	COG1530	ribonuclease E activity
I7V34_RS10695	COG1994	Peptidase M50
I7V34_RS10700	COG0739	heme binding
I7V34_RS10705	COG2894	cell division
I7V34_RS10710	COG0850	regulation of cytokinetic process
I7V34_RS10715	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
I7V34_RS10720	COG1792	Involved in formation and maintenance of cell shape
I7V34_RS10725	COG1077	Cell shape determining protein MreB Mrl
I7V34_RS10730	COG2003	Belongs to the UPF0758 family
I7V34_RS10760	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
I7V34_RS10765	COG2165	general secretion pathway protein
I7V34_RS10770	COG1459	type II secretion system
I7V34_RS10780	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
I7V34_RS10795	COG3706	GGDEF domain
I7V34_RS10800	COG0285	dihydrofolate synthase activity
I7V34_RS10805	COG0525	valine-tRNA ligase activity
I7V34_RS10815	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
I7V34_RS10820	COG1388	LysM domain
I7V34_RS10820	COG1388	LysM domain
I7V34_RS10825	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
I7V34_RS10830	COG0113	porphobilinogen synthase activity
I7V34_RS10845	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
I7V34_RS10860	COG5553	Cysteine dioxygenase type I
I7V34_RS10865	COG0697	spore germination
I7V34_RS10870	COG1126	abc transporter atp-binding protein
I7V34_RS10875	COG0765	amino acid transport
I7V34_RS10880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I7V34_RS10885	COG0218	Necessary for normal cell division and for the maintenance of normal septation
I7V34_RS10890	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
I7V34_RS10895	COG0470	DNA polymerase III
I7V34_RS10895	COG1067	ATP-dependent peptidase activity
I7V34_RS10900	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
I7V34_RS10905	COG0544	peptidyl-prolyl cis-trans isomerase activity
I7V34_RS10910	COG0457	Tetratricopeptide repeat
I7V34_RS10910	COG1477	protein flavinylation
I7V34_RS10920	COG0622	Phosphoesterase
I7V34_RS10935	COG5401	PFAM Sporulation and spore germination
I7V34_RS10950	COG1846	Transcriptional regulator
I7V34_RS10955	COG2197	response regulator
I7V34_RS10960	COG0824	Thioesterase
I7V34_RS10965	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
I7V34_RS10970	COG1053	succinate dehydrogenase
I7V34_RS10975	COG2009	succinate dehydrogenase
I7V34_RS10980	COG1719	4-vinyl reductase, 4VR
I7V34_RS10990	COG0322	excinuclease ABC activity
I7V34_RS10995	COG3118	belongs to the thioredoxin family
I7V34_RS11000	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
I7V34_RS11005	COG2086	electron transfer activity
I7V34_RS11010	COG1024	Enoyl-CoA hydratase
I7V34_RS11015	COG1309	transcriptional regulator
I7V34_RS11020	COG0318	PFAM AMP-dependent synthetase and ligase
I7V34_RS11025	COG3459	Glycosyltransferase 36 associated
I7V34_RS11030	COG3766	membrane
I7V34_RS11035	COG1193	negative regulation of DNA recombination
I7V34_RS11040	COG1796	DNA polymerase
I7V34_RS11040	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
I7V34_RS11045	COG1286	toxin biosynthetic process
I7V34_RS11050	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
I7V34_RS11060	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
I7V34_RS11060	COG0072	phenylalanine-tRNA ligase activity
I7V34_RS11065	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
I7V34_RS11070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
I7V34_RS11080	COG1335	isochorismatase
I7V34_RS11085	COG1363	Peptidase, m42
I7V34_RS11110	COG1181	Belongs to the D-alanine--D-alanine ligase family
I7V34_RS11115	COG0189	ligase activity
I7V34_RS11120	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
I7V34_RS11135	COG0398	Pfam SNARE associated Golgi protein
I7V34_RS11145	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
I7V34_RS11155	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
I7V34_RS11160	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
I7V34_RS11170	COG1484	DNA-dependent DNA replication
I7V34_RS11175	COG3611	Membrane attachment protein
I7V34_RS11180	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
I7V34_RS11190	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
I7V34_RS11195	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
I7V34_RS11205	COG1971	Probably functions as a manganese efflux pump
I7V34_RS11210	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
I7V34_RS11215	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
I7V34_RS11215	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
I7V34_RS11220	COG0330	HflC and HflK could
I7V34_RS11225	COG0330	HflC and HflK could
I7V34_RS11230	COG5002	protein histidine kinase activity
I7V34_RS11235	COG0745	RESPONSE REGULATOR receiver
I7V34_RS11245	COG0039	L-malate dehydrogenase activity
I7V34_RS11250	COG0538	isocitrate dehydrogenase activity
I7V34_RS11255	COG0372	Belongs to the citrate synthase family
I7V34_RS11260	COG0628	permease
I7V34_RS11265	COG3030	protein affecting phage T7 exclusion by the F plasmid
I7V34_RS11275	COG0205	6-phosphofructokinase activity
I7V34_RS11280	COG0825	malonyl-CoA metabolic process
I7V34_RS11285	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
I7V34_RS11290	COG1725	Transcriptional regulator
I7V34_RS11295	COG0281	malic enzyme
I7V34_RS11300	COG0587	DNA-directed DNA polymerase activity
I7V34_RS11315	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
I7V34_RS11325	COG4109	DRTGG domain
I7V34_RS11355	COG0589	response to stress
I7V34_RS11360	COG0165	Argininosuccinate lyase
I7V34_RS11365	COG0137	argininosuccinate synthase activity
I7V34_RS11375	COG2217	Heavy metal translocating P-type atpase
I7V34_RS11380	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
I7V34_RS11385	COG0827	DNA restriction-modification system
I7V34_RS11390	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
I7V34_RS11395	COG3874	Sporulation protein YtfJ
I7V34_RS11405	COG1714	RDD family
I7V34_RS11410	COG0616	signal peptide processing
I7V34_RS11415	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
I7V34_RS11420	COG2962	Rard protein
I7V34_RS11425	COG1574	metal-dependent hydrolase with the TIM-barrel fold
I7V34_RS11430	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
I7V34_RS11440	COG0301	tRNA thio-modification
I7V34_RS11445	COG1104	cysteine desulfurase activity
I7V34_RS11450	COG1114	Component of the transport system for branched-chain amino acids
I7V34_RS11455	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
I7V34_RS11460	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
I7V34_RS11465	COG1309	transcriptional regulator
I7V34_RS11470	COG1956	GAF domain-containing protein
I7V34_RS11480	COG2203	Gaf domain
I7V34_RS11480	COG2199	diguanylate cyclase activity
I7V34_RS11485	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
I7V34_RS11490	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
I7V34_RS11495	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
I7V34_RS11500	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
I7V34_RS11505	COG0454	-acetyltransferase
I7V34_RS11510	COG0517	IMP dehydrogenase activity
I7V34_RS11515	COG0123	including yeast histone deacetylase and acetoin utilization protein
I7V34_RS11535	COG1605	Chorismate mutase
I7V34_RS11535	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
I7V34_RS11540	COG0849	cell division
I7V34_RS11555	COG4980	gas vesicle protein
I7V34_RS11570	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
I7V34_RS11580	COG1674	ftsk spoiiie
I7V34_RS11585	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
I7V34_RS11590	COG4848	Belongs to the UPF0354 family
I7V34_RS11595	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I7V34_RS11615	COG3104	oligopeptide transport
I7V34_RS11625	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
I7V34_RS11630	COG1363	Peptidase, m42
I7V34_RS11640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I7V34_RS11645	COG0220	tRNA (guanine-N7-)-methyltransferase activity
I7V34_RS11655	COG0510	thiamine kinase activity
I7V34_RS11660	COG1523	belongs to the glycosyl hydrolase 13 family
I7V34_RS11665	COG1597	lipid kinase activity
I7V34_RS11680	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
I7V34_RS11695	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
I7V34_RS11700	COG1349	DNA-binding transcription factor activity
I7V34_RS11705	COG1187	pseudouridine synthase activity
I7V34_RS11715	COG2244	polysaccharide biosynthetic process
I7V34_RS11720	COG2081	HI0933 family
I7V34_RS11730	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
I7V34_RS11735	COG0495	leucyl-tRNA aminoacylation
I7V34_RS11740	COG1028	Short-chain dehydrogenase reductase Sdr
I7V34_RS11745	COG2610	gluconate transmembrane transporter activity
I7V34_RS11750	COG3829	transcription factor binding
I7V34_RS11750	COG3290	protein histidine kinase activity
I7V34_RS11755	COG4297	protein containing double-stranded beta helix domain
I7V34_RS11760	COG3547	Transposase (IS116 IS110 IS902 family)
I7V34_RS11765	COG2814	Major facilitator Superfamily
I7V34_RS11780	COG1242	4 iron, 4 sulfur cluster binding
I7V34_RS11785	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
I7V34_RS11790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
I7V34_RS11805	COG2267	carboxylic ester hydrolase activity
I7V34_RS11810	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
I7V34_RS11815	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
I7V34_RS11820	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
I7V34_RS11835	COG1268	BioY protein
I7V34_RS11850	COG1506	peptidase
I7V34_RS11855	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
I7V34_RS11860	COG1116	anion transmembrane transporter activity
I7V34_RS11865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
I7V34_RS11900	COG1854	S-ribosylhomocysteine lyase activity
I7V34_RS11905	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
I7V34_RS11915	COG1271	oxidase subunit
I7V34_RS11920	COG1294	oxidase, subunit
I7V34_RS11925	COG4948	Mandelate Racemase Muconate Lactonizing
I7V34_RS11930	COG0318	PFAM AMP-dependent synthetase and ligase
I7V34_RS11935	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
I7V34_RS11940	COG0596	Alpha beta hydrolase
I7V34_RS11945	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
I7V34_RS11950	COG1169	isochorismate synthase
I7V34_RS11955	COG1575	Belongs to the MenA family. Type 1 subfamily
I7V34_RS11960	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
I7V34_RS11965	COG0058	SHG alpha-glucan phosphorylase activity
I7V34_RS11970	COG0297	glycogen (starch) synthase activity
I7V34_RS11975	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
I7V34_RS11980	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
I7V34_RS11990	COG0246	Mannitol dehydrogenase
I7V34_RS11995	COG3711	transcriptional antiterminator
I7V34_RS12000	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
I7V34_RS12000	COG2213	PTS system mannitol-specific
I7V34_RS12140	COG1285	pathogenesis
I7V34_RS12145	COG1285	pathogenesis
I7V34_RS12150	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
I7V34_RS12150	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I7V34_RS12150	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I7V34_RS12155	COG1105	Belongs to the carbohydrate kinase PfkB family
I7V34_RS12160	COG1349	DNA-binding transcription factor activity
I7V34_RS12165	COG1368	sulfuric ester hydrolase activity
I7V34_RS12170	COG0561	phosphatase activity
I7V34_RS12175	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
I7V34_RS12190	COG1607	acyl-coa hydrolase
I7V34_RS12195	COG0583	DNA-binding transcription factor activity
I7V34_RS12210	COG3876	Protein conserved in bacteria
I7V34_RS12215	COG1472	Belongs to the glycosyl hydrolase 3 family
I7V34_RS12220	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
I7V34_RS12225	COG0415	Belongs to the DNA photolyase family
I7V34_RS12240	COG1595	DNA-templated transcription, initiation
I7V34_RS12255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
I7V34_RS12260	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
I7V34_RS12275	COG1979	alcohol dehydrogenase
I7V34_RS12280	COG2155	Conserved Protein
I7V34_RS12285	COG1012	belongs to the aldehyde dehydrogenase family
I7V34_RS12290	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
I7V34_RS12295	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
I7V34_RS12300	COG3829	transcription factor binding
I7V34_RS12305	COG0753	catalase activity
I7V34_RS12315	COG1012	belongs to the aldehyde dehydrogenase family
I7V34_RS12325	COG1098	S1 RNA binding domain
I7V34_RS12335	COG1595	DNA-templated transcription, initiation
I7V34_RS12345	COG0733	neurotransmitter:sodium symporter activity
I7V34_RS12355	COG0436	Aminotransferase
I7V34_RS12360	COG1522	sequence-specific DNA binding
I7V34_RS12365	COG2267	carboxylic ester hydrolase activity
I7V34_RS12370	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
I7V34_RS12375	COG2032	superoxide dismutase activity
I7V34_RS12385	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
I7V34_RS12395	COG5018	Exonuclease
I7V34_RS12400	COG2814	Major facilitator Superfamily
I7V34_RS12405	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
I7V34_RS12425	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
I7V34_RS12425	COG2111	Na H antiporter
I7V34_RS12430	COG2111	Na H antiporter
I7V34_RS12435	COG1006	Multisubunit Na H antiporter MnhC subunit
I7V34_RS12440	COG0651	ATP synthesis coupled electron transport
I7V34_RS12445	COG1863	multisubunit Na H antiporter MnhE subunit
I7V34_RS12450	COG2212	antiporter activity
I7V34_RS12455	COG1320	monovalent cation:proton antiporter activity
I7V34_RS12460	COG4876	unkown
I7V34_RS12465	COG2050	protein possibly involved in aromatic compounds catabolism
I7V34_RS12490	COG2056	Na+-H+ antiporter family
I7V34_RS12495	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
I7V34_RS12500	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
I7V34_RS12505	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
I7V34_RS12510	COG3584	3D domain protein
I7V34_RS12535	COG1252	NADH dehydrogenase
I7V34_RS12550	COG0316	Belongs to the HesB IscA family
I7V34_RS12565	COG4844	belongs to the
I7V34_RS12570	COG1252	NADH dehydrogenase
I7V34_RS12575	COG4837	Protein of unknown function (DUF1462)
I7V34_RS12580	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
I7V34_RS12590	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
I7V34_RS12595	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
I7V34_RS12600	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
I7V34_RS12620	COG0647	UMP catabolic process
I7V34_RS12625	COG2445	Protein of unknown function DUF86
I7V34_RS12640	COG4470	Protein conserved in bacteria
I7V34_RS12650	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
I7V34_RS12655	COG0739	heme binding
I7V34_RS12665	COG0733	neurotransmitter:sodium symporter activity
I7V34_RS12670	COG1231	oxidoreductase activity
I7V34_RS12675	COG1757	Na H antiporter
I7V34_RS12690	COG3377	Domain of unknown function (DUF1805)
I7V34_RS12695	COG0737	Belongs to the 5'-nucleotidase family
I7V34_RS12700	COG0730	response to heat
I7V34_RS12705	COG1801	Protein of unknown function DUF72
I7V34_RS12710	COG0719	Fe-S assembly protein
I7V34_RS12715	COG0822	iron-sulfur transferase activity
I7V34_RS12720	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
I7V34_RS12725	COG0719	Fe-S assembly protein
I7V34_RS12730	COG0396	ATPase activity
I7V34_RS12740	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
I7V34_RS12745	COG1464	Belongs to the NlpA lipoprotein family
I7V34_RS12750	COG2011	ABC-type metal ion transport system permease component
I7V34_RS12755	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
I7V34_RS12765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I7V34_RS12770	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
I7V34_RS12780	COG0509	glycine decarboxylation via glycine cleavage system
I7V34_RS12785	COG1393	Belongs to the ArsC family
I7V34_RS12795	COG4221	oxidoreductase activity
I7V34_RS12800	COG1960	acyl-CoA dehydrogenase activity
I7V34_RS12805	COG0183	Belongs to the thiolase family
I7V34_RS12810	COG1024	Enoyl-CoA hydratase
I7V34_RS12810	COG1250	3-hydroxyacyl-CoA dehydrogenase
I7V34_RS12820	COG2364	Membrane
I7V34_RS12825	COG0385	Bile acid
I7V34_RS12835	COG0506	proline dehydrogenase activity
I7V34_RS12845	COG5577	PFAM Coat F domain
I7V34_RS12860	COG1120	ATPase activity
I7V34_RS12865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I7V34_RS12870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I7V34_RS12875	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
I7V34_RS12895	COG0673	inositol 2-dehydrogenase activity
I7V34_RS12900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I7V34_RS12920	COG1785	Belongs to the alkaline phosphatase family
I7V34_RS12925	COG1834	amidinotransferase
I7V34_RS12940	COG0318	PFAM AMP-dependent synthetase and ligase
I7V34_RS12955	COG0655	NAD(P)H dehydrogenase (quinone) activity
I7V34_RS12965	COG1764	response to oxidative stress
I7V34_RS12980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
I7V34_RS12990	COG2514	catechol 2,3-dioxygenase activity
I7V34_RS12995	COG2259	Doxx family
I7V34_RS13000	COG1733	regulation of RNA biosynthetic process
I7V34_RS13020	COG1082	Xylose isomerase domain protein TIM barrel
I7V34_RS13050	COG0076	glutamate decarboxylase activity
I7V34_RS13060	COG2271	Major facilitator Superfamily
I7V34_RS13065	COG2814	Major facilitator Superfamily
I7V34_RS13080	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
I7V34_RS13090	COG1309	transcriptional regulator
I7V34_RS13110	COG2304	oxidoreductase activity
I7V34_RS13140	COG1733	regulation of RNA biosynthetic process
I7V34_RS13150	COG3403	YqcI/YcgG family
I7V34_RS13155	COG1280	lysine exporter protein (LysE YggA)
I7V34_RS13160	COG5577	PFAM Coat F domain
I7V34_RS13170	COG1309	transcriptional regulator
I7V34_RS13175	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
I7V34_RS13180	COG1845	cytochrome c oxidase, subunit III
I7V34_RS13210	COG1027	Aspartate ammonia-lyase
I7V34_RS13215	COG0791	NLP P60 protein
I7V34_RS13215	COG1388	LysM domain
I7V34_RS13220	COG3842	ATPase activity
I7V34_RS13230	COG1840	ABC-type Fe3 transport system, periplasmic component
I7V34_RS13240	COG0640	Transcriptional regulator
I7V34_RS13245	COG1612	heme a metabolic process
I7V34_RS13265	COG3192	ethanolamine utilization protein
I7V34_RS13270	COG0006	proline dipeptidase activity
I7V34_RS13275	COG3290	protein histidine kinase activity
I7V34_RS13275	COG3829	transcription factor binding
I7V34_RS13280	COG1114	Component of the transport system for branched-chain amino acids
I7V34_RS13285	COG2186	Transcriptional regulator
I7V34_RS13300	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
I7V34_RS13305	COG0557	exoribonuclease II activity
I7V34_RS13310	COG1647	Serine aminopeptidase, S33
I7V34_RS13315	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
I7V34_RS13320	COG0148	phosphopyruvate hydratase activity
I7V34_RS13355	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
I7V34_RS13375	COG5002	protein histidine kinase activity
I7V34_RS13380	COG0745	RESPONSE REGULATOR receiver
I7V34_RS13400	COG3706	GGDEF domain
I7V34_RS13405	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
I7V34_RS13415	COG0391	Required for morphogenesis under gluconeogenic growth conditions
I7V34_RS13420	COG1660	Displays ATPase and GTPase activities
I7V34_RS13425	COG1051	belongs to the nudix hydrolase family
I7V34_RS13445	COG0492	ferredoxin-NADP+ reductase activity
I7V34_RS13450	COG0457	Tetratricopeptide repeat
I7V34_RS13455	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
I7V34_RS13455	COG0140	phosphoribosyl-ATP diphosphatase activity
I7V34_RS13460	COG0107	imidazoleglycerol-phosphate synthase activity
I7V34_RS13465	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
I7V34_RS13470	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
I7V34_RS13475	COG0131	Imidazoleglycerol-phosphate dehydratase
I7V34_RS13480	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
I7V34_RS13490	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
I7V34_RS13495	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
I7V34_RS13500	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
I7V34_RS13505	COG0110	maltose O-acetyltransferase activity
I7V34_RS13510	COG0546	phosphoglycolate phosphatase activity
I7V34_RS13515	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
I7V34_RS13520	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
I7V34_RS13525	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
I7V34_RS13535	COG1950	PFAM Membrane protein of
I7V34_RS13540	COG1983	PspC domain protein
I7V34_RS13545	COG3595	metallopeptidase activity
I7V34_RS13565	COG1136	(ABC) transporter
I7V34_RS13575	COG1464	Belongs to the NlpA lipoprotein family
I7V34_RS13580	COG2011	ABC-type metal ion transport system permease component
I7V34_RS13590	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
I7V34_RS13595	COG0556	nucleotide-excision repair
I7V34_RS13600	COG4897	Protein conserved in bacteria
I7V34_RS13610	COG0596	Alpha beta hydrolase
I7V34_RS13615	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
I7V34_RS13640	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
I7V34_RS13645	COG0569	domain protein
I7V34_RS13670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I7V34_RS13670	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
I7V34_RS13675	COG1301	dicarboxylic acid transport
I7V34_RS13680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
I7V34_RS13685	COG3243	poly(R)-hydroxyalkanoic acid synthase
I7V34_RS13695	COG1028	Short-chain dehydrogenase reductase Sdr
I7V34_RS13700	COG0793	Belongs to the peptidase S41A family
I7V34_RS13700	COG3409	Peptidoglycan-binding domain 1 protein
I7V34_RS13705	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
I7V34_RS13715	COG0626	cystathionine gamma-synthase activity
I7V34_RS13725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I7V34_RS13740	COG0745	RESPONSE REGULATOR receiver
I7V34_RS13745	COG0785	Cytochrome C biogenesis protein
I7V34_RS13760	COG0739	heme binding
I7V34_RS13765	COG2177	Part of the ABC transporter FtsEX involved in
I7V34_RS13770	COG2884	Cell division ATP-binding protein ftsE
I7V34_RS13775	COG2010	Cytochrome c
I7V34_RS13780	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
I7V34_RS13790	COG0653	protein targeting
I7V34_RS13795	COG3012	SEC-C Motif Domain Protein
I7V34_RS13795	COG1405	negative regulation of cell septum assembly
I7V34_RS13835	COG1516	flagellar protein fliS
I7V34_RS13840	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
I7V34_RS13845	COG1334	flagellar protein FlaG
I7V34_RS13850	COG4932	domain protein
I7V34_RS13850	COG5492	domain, Protein
I7V34_RS13860	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
I7V34_RS13865	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
I7V34_RS13875	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
I7V34_RS13880	COG4786	Flagellar basal body rod
I7V34_RS13880	COG1256	bacterial-type flagellum assembly
I7V34_RS13900	COG1040	competence protein
I7V34_RS13905	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
I7V34_RS13915	COG1307	EDD domain protein, DegV family
I7V34_RS13925	COG0737	Belongs to the 5'-nucleotidase family
I7V34_RS13935	COG0812	UDP-N-acetylmuramate dehydrogenase activity
I7V34_RS13980	COG0346	lactoylglutathione lyase activity
I7V34_RS13990	COG1227	inorganic diphosphatase activity
I7V34_RS14010	COG0768	penicillin binding
I7V34_RS14020	COG0737	Belongs to the 5'-nucleotidase family
I7V34_RS14025	COG1404	Belongs to the peptidase S8 family
I7V34_RS14040	COG1175	transmembrane transport
I7V34_RS14045	COG3842	ATPase activity
I7V34_RS14055	COG2011	ABC-type metal ion transport system permease component
I7V34_RS14060	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
I7V34_RS14085	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
I7V34_RS14110	COG1999	signal sequence binding
I7V34_RS14170	COG0366	Alpha amylase catalytic
I7V34_RS14180	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
I7V34_RS14195	COG2188	Transcriptional regulator
I7V34_RS14210	COG0579	oxidoreductase
I7V34_RS14230	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
I7V34_RS14235	COG0673	inositol 2-dehydrogenase activity
I7V34_RS14250	COG3458	cephalosporin-C deacetylase activity
I7V34_RS14260	COG0673	inositol 2-dehydrogenase activity
I7V34_RS14265	COG0673	inositol 2-dehydrogenase activity
I7V34_RS14295	COG0395	ABC-type sugar transport system, permease component
I7V34_RS14305	COG1653	transport
I7V34_RS14310	COG5578	integral membrane protein
I7V34_RS14340	COG0395	ABC-type sugar transport system, permease component
I7V34_RS14345	COG1175	transmembrane transport
I7V34_RS14350	COG1653	transport
I7V34_RS14355	COG1737	Transcriptional regulator
I7V34_RS14375	COG0681	Belongs to the peptidase S26 family
I7V34_RS14385	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
I7V34_RS14395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
I7V34_RS14405	COG2814	Major facilitator Superfamily
I7V34_RS14415	COG1388	LysM domain
I7V34_RS14415	COG0791	NLP P60 protein
I7V34_RS14420	COG5002	protein histidine kinase activity
I7V34_RS14450	COG4187	Peptidase family M20/M25/M40
I7V34_RS14455	COG0436	Aminotransferase
I7V34_RS14460	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
I7V34_RS14460	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
I7V34_RS14470	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
I7V34_RS14475	COG1802	Transcriptional regulator
I7V34_RS14480	COG0277	FAD linked oxidase domain protein
I7V34_RS14490	COG1595	DNA-templated transcription, initiation
I7V34_RS14550	COG1621	beta-fructofuranosidase activity
I7V34_RS14555	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I7V34_RS14555	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I7V34_RS14555	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
I7V34_RS14560	COG3711	transcriptional antiterminator
I7V34_RS14560	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
I7V34_RS14570	COG1929	Belongs to the glycerate kinase type-1 family
I7V34_RS14580	COG0383	alpha-mannosidase activity
I7V34_RS14585	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I7V34_RS14595	COG1482	cell wall glycoprotein biosynthetic process
I7V34_RS14605	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
I7V34_RS14610	COG1940	carbohydrate kinase activity
I7V34_RS14615	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
I7V34_RS14625	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
I7V34_RS14630	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
I7V34_RS14635	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
I7V34_RS14640	COG1210	Utp--glucose-1-phosphate uridylyltransferase
I7V34_RS14645	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
I7V34_RS14715	COG0471	metal ion transport
I7V34_RS14820	COG0110	maltose O-acetyltransferase activity
I7V34_RS14825	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
I7V34_RS14835	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
I7V34_RS14855	COG1216	Glycosyl transferase, family 2
I7V34_RS14870	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
I7V34_RS14880	COG4464	protein tyrosine phosphatase activity
I7V34_RS14885	COG0489	protein tyrosine kinase activity
I7V34_RS14890	COG3944	biosynthesis protein
I7V34_RS14900	COG1316	TRANSCRIPTIONal
I7V34_RS14910	COG1388	LysM domain
I7V34_RS14910	COG0791	NLP P60 protein
I7V34_RS14915	COG1263	PTS System
I7V34_RS14915	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I7V34_RS14920	COG0366	Alpha amylase catalytic
I7V34_RS14935	COG2188	Transcriptional regulator
I7V34_RS14940	COG2197	response regulator
I7V34_RS14945	COG4585	Histidine kinase
I7V34_RS14950	COG1739	Uncharacterized protein family UPF0029
I7V34_RS14955	COG1316	TRANSCRIPTIONal
I7V34_RS14965	COG3307	-O-antigen
I7V34_RS14970	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
I7V34_RS15010	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
I7V34_RS15015	COG2247	cell wall binding repeat
I7V34_RS15015	COG0860	N-Acetylmuramoyl-L-alanine amidase
I7V34_RS15020	COG0860	N-Acetylmuramoyl-L-alanine amidase
I7V34_RS15020	COG2247	cell wall binding repeat
I7V34_RS15025	COG2247	cell wall binding repeat
I7V34_RS15025	COG2385	sporulation resulting in formation of a cellular spore
I7V34_RS15050	COG0438	transferase activity, transferring glycosyl groups
I7V34_RS15090	COG2247	cell wall binding repeat
I7V34_RS15090	COG0860	N-Acetylmuramoyl-L-alanine amidase
I7V34_RS15095	COG0791	NLP P60 protein
I7V34_RS15095	COG1388	LysM domain
I7V34_RS15120	COG1595	DNA-templated transcription, initiation
I7V34_RS15125	COG0010	Belongs to the arginase family
I7V34_RS15130	COG1228	amidohydrolase
I7V34_RS15135	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
I7V34_RS15140	COG2986	histidine ammonia-lyase
I7V34_RS15175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I7V34_RS15180	COG1785	Belongs to the alkaline phosphatase family
I7V34_RS15185	COG4715	Zinc finger, swim domain protein
I7V34_RS15190	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
I7V34_RS15200	COG0629	single-stranded DNA binding
I7V34_RS15210	COG1396	sequence-specific DNA binding
I7V34_RS15230	COG3764	Sortase (surface protein transpeptidase)
I7V34_RS15255	COG4786	Flagellar basal body rod
I7V34_RS15260	COG4786	Flagellar basal body rod
I7V34_RS15265	COG1077	Cell shape determining protein MreB Mrl
I7V34_RS15270	COG1609	Transcriptional regulator
I7V34_RS15275	COG2176	DNA-directed DNA polymerase activity
I7V34_RS15275	COG5002	protein histidine kinase activity
I7V34_RS15280	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
I7V34_RS15285	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
I7V34_RS15300	COG0739	heme binding
I7V34_RS15310	COG2385	sporulation resulting in formation of a cellular spore
I7V34_RS15315	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
I7V34_RS15325	COG4836	Membrane
I7V34_RS15340	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
I7V34_RS15355	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
I7V34_RS15360	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
I7V34_RS15365	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
I7V34_RS15370	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
I7V34_RS15375	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
I7V34_RS15385	COG0356	it plays a direct role in the translocation of protons across the membrane
I7V34_RS15400	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
I7V34_RS15405	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
I7V34_RS15415	COG0698	ribose 5-phosphate isomerase
I7V34_RS15420	COG0840	transmembrane signaling receptor activity
I7V34_RS15430	COG1971	Probably functions as a manganese efflux pump
I7V34_RS15435	COG0009	L-threonylcarbamoyladenylate synthase
I7V34_RS15440	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
I7V34_RS15455	COG1619	proteins homologs of microcin C7 resistance protein MccF
I7V34_RS15465	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
I7V34_RS15475	COG1435	thymidine kinase activity
I7V34_RS15485	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
I7V34_RS15490	COG1494	fructose-1,6-bisphosphatase
I7V34_RS15495	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
I7V34_RS15500	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
I7V34_RS15505	COG0191	fructose-bisphosphate aldolase activity
I7V34_RS15510	COG2204	response regulator
I7V34_RS15515	COG4821	SIS domain
I7V34_RS15520	COG0504	CTP synthase activity
I7V34_RS15535	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
I7V34_RS15535	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
I7V34_RS15535	COG1703	isobutyryl-CoA mutase activity
I7V34_RS15545	COG1960	acyl-CoA dehydrogenase activity
I7V34_RS15550	COG1960	acyl-CoA dehydrogenase activity
I7V34_RS15555	COG1250	3-hydroxyacyl-CoA dehydrogenase
I7V34_RS15560	COG0183	Belongs to the thiolase family
I7V34_RS15565	COG2181	nitrate reductase activity
I7V34_RS15565	COG0247	lactate metabolic process
I7V34_RS15570	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
I7V34_RS15595	COG0018	arginyl-trna synthetase
I7V34_RS15600	COG4506	Protein conserved in bacteria
I7V34_RS15610	COG0010	Belongs to the arginase family
I7V34_RS15615	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
I7V34_RS15620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
I7V34_RS15645	COG1994	Peptidase M50
I7V34_RS15660	COG3465	dGTPase activity
I7V34_RS15665	COG1078	dGTPase activity
I7V34_RS15680	COG4473	ABC transporter
I7V34_RS15685	COG1131	(ABC) transporter
I7V34_RS15690	COG0450	alkyl hydroperoxide reductase
I7V34_RS15695	COG0095	Lipoate-protein ligase
I7V34_RS15700	COG0280	phosphate acetyltransferase
I7V34_RS15710	COG1705	Flagellar rod assembly protein muramidase FlgJ
I7V34_RS15710	COG1388	LysM domain
I7V34_RS15715	COG3773	Cell wall hydrolase
I7V34_RS15730	COG2363	Small membrane protein
I7V34_RS15745	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
I7V34_RS15760	COG0351	phosphomethylpyrimidine kinase
I7V34_RS15765	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
I7V34_RS15775	COG1131	(ABC) transporter
I7V34_RS15820	COG2133	pyrroloquinoline quinone binding
I7V34_RS15825	COG0561	phosphatase activity
I7V34_RS15835	COG2031	fatty acid transporter
I7V34_RS15840	COG3314	Sporulation integral membrane protein YlbJ
I7V34_RS15845	COG2244	polysaccharide biosynthetic process
I7V34_RS15850	COG4191	Histidine kinase
I7V34_RS15860	COG0156	8-amino-7-oxononanoate synthase activity
I7V34_RS15880	COG2318	DinB family
I7V34_RS15885	COG2364	Membrane
I7V34_RS15895	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
I7V34_RS15900	COG1028	Short-chain dehydrogenase reductase Sdr
I7V34_RS15905	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
I7V34_RS15910	COG2076	Multidrug Resistance protein
I7V34_RS15915	COG2076	Multidrug Resistance protein
I7V34_RS15920	COG0446	pyridine nucleotide-disulphide oxidoreductase
I7V34_RS15925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
I7V34_RS15925	COG0723	plastoquinol--plastocyanin reductase activity
I7V34_RS15935	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
I7V34_RS15935	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
I7V34_RS15940	COG0596	Alpha beta hydrolase
I7V34_RS16075	COG1028	Short-chain dehydrogenase reductase Sdr
I7V34_RS16080	COG2610	gluconate transmembrane transporter activity
I7V34_RS16085	COG0583	DNA-binding transcription factor activity
I7V34_RS16095	COG1562	ergosterol biosynthetic process
I7V34_RS16120	COG0673	inositol 2-dehydrogenase activity
I7V34_RS16150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
I7V34_RS16155	COG3314	Sporulation integral membrane protein YlbJ
I7V34_RS16165	COG0579	oxidoreductase
I7V34_RS16170	COG0584	glycerophosphoryl diester phosphodiesterase
I7V34_RS16175	COG0714	Associated with various cellular activities
I7V34_RS16205	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
I7V34_RS16210	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
I7V34_RS16215	COG2169	Transcriptional regulator
I7V34_RS16225	COG1695	Transcriptional regulator
I7V34_RS16230	COG3402	PFAM membrane-flanked domain
I7V34_RS16240	COG0662	Cupin 2, conserved barrel domain protein
I7V34_RS16250	COG1695	Transcriptional regulator
I7V34_RS16265	COG1131	(ABC) transporter
I7V34_RS16280	COG1846	Transcriptional regulator
I7V34_RS16285	COG1764	response to oxidative stress
I7V34_RS16295	COG4682	membrane
I7V34_RS16330	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
I7V34_RS16355	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
I7V34_RS16360	COG2814	Major facilitator Superfamily
I7V34_RS16365	COG0667	Aldo Keto reductase
I7V34_RS16370	COG0673	inositol 2-dehydrogenase activity
I7V34_RS16375	COG1113	amino acid transport
I7V34_RS16395	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
I7V34_RS16405	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
I7V34_RS16410	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
I7V34_RS16420	COG4863	YycH protein
I7V34_RS16425	COG5002	protein histidine kinase activity
I7V34_RS16430	COG0745	RESPONSE REGULATOR receiver
I7V34_RS16475	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
I7V34_RS16480	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
I7V34_RS16485	COG1132	(ABC) transporter
I7V34_RS16490	COG0305	Participates in initiation and elongation during chromosome replication
I7V34_RS16495	COG0359	binds to the 23S rRNA
I7V34_RS16500	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
I7V34_RS16505	COG4241	membrane
I7V34_RS16510	COG0840	transmembrane signaling receptor activity
I7V34_RS16515	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
I7V34_RS16525	COG0360	Binds together with S18 to 16S ribosomal RNA
I7V34_RS16530	COG0012	GTP binding
I7V34_RS16535	COG4481	Protein conserved in bacteria
I7V34_RS16540	COG0668	transmembrane transport
I7V34_RS16555	COG1475	DNA binding
I7V34_RS16560	COG1192	Involved in chromosome partitioning
I7V34_RS16575	COG1475	DNA binding
I7V34_RS16580	COG0357	Ribosomal RNA small subunit methyltransferase G
I7V34_RS16590	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
I7V34_RS16595	COG1847	R3H domain protein
I7V34_RS16605	COG0594	ribonuclease P activity
I7V34_RS16615	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
I7V34_RS16620	COG0592	DNA-directed DNA polymerase activity
I7V34_RS16625	COG2501	S4 domain
I7V34_RS16630	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
I7V34_RS16640	COG0187	DNA topoisomerase II activity
I7V34_RS16645	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
I7V34_RS16680	COG0386	Belongs to the glutathione peroxidase family
I7V34_RS16690	COG0516	GMP reductase activity
I7V34_RS16690	COG0517	IMP dehydrogenase activity
I7V34_RS16705	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
I7V34_RS16710	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
I7V34_RS16725	COG1428	Deoxynucleoside kinase
I7V34_RS16730	COG1428	Deoxynucleoside kinase
I7V34_RS16740	COG3858	chitin binding
I7V34_RS16740	COG1388	LysM domain
I7V34_RS16745	COG1335	isochorismatase
I7V34_RS16750	COG0590	tRNA wobble adenosine to inosine editing
I7V34_RS16760	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
I7V34_RS16765	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
I7V34_RS16770	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
I7V34_RS16825	COG1982	Orn Lys Arg decarboxylase major
I7V34_RS16835	COG3870	Protein conserved in bacteria
I7V34_RS16840	COG1728	Protein conserved in bacteria
I7V34_RS16845	COG0470	DNA polymerase III
I7V34_RS16850	COG1774	PSP1 C-terminal conserved region
I7V34_RS16855	COG4467	Involved in initiation control of chromosome replication
I7V34_RS16860	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
I7V34_RS16865	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
I7V34_RS16870	COG2002	toxin-antitoxin pair type II binding
I7V34_RS16880	COG0084	hydrolase, TatD family'
I7V34_RS16885	COG3584	3D domain protein
I7V34_RS16885	COG3583	domain protein
I7V34_RS16905	COG4466	Protein conserved in bacteria
I7V34_RS16920	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
I7V34_RS16925	COG0251	oxidation-reduction process
I7V34_RS16960	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
I7V34_RS16965	COG2002	toxin-antitoxin pair type II binding
I7V34_RS16970	COG2244	polysaccharide biosynthetic process
I7V34_RS16975	COG3956	TIGRFAM MazG family protein
I7V34_RS16980	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
I7V34_RS16995	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
I7V34_RS17000	COG1098	S1 RNA binding domain
I7V34_RS17020	COG2208	phosphoserine phosphatase activity
I7V34_RS17025	COG2304	oxidoreductase activity
I7V34_RS17030	COG0515	serine threonine protein kinase
I7V34_RS17035	COG0037	tRNA processing
I7V34_RS17040	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
I7V34_RS17045	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
I7V34_RS17055	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
I7V34_RS17060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
I7V34_RS17065	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
I7V34_RS17070	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
I7V34_RS17075	COG0512	Glutamine amidotransferase of anthranilate synthase
I7V34_RS17080	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
I7V34_RS17085	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
I7V34_RS17090	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
I7V34_RS17095	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
I7V34_RS17100	COG1396	sequence-specific DNA binding
I7V34_RS17190	COG3880	PFAM UvrB UvrC protein
I7V34_RS17195	COG3869	Catalyzes the specific phosphorylation of arginine residues in
I7V34_RS17200	COG0542	response to heat
I7V34_RS17205	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
I7V34_RS17210	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
I7V34_RS17215	COG4956	integral membrane protein (PIN domain superfamily)
I7V34_RS17230	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
I7V34_RS17235	COG1045	serine acetyltransferase
I7V34_RS17240	COG0215	cysteine-tRNA ligase activity
I7V34_RS17250	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
I7V34_RS17255	COG3688	RNA-binding protein containing a PIN domain
I7V34_RS17265	COG0267	Belongs to the bacterial ribosomal protein bL33 family
I7V34_RS17270	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
I7V34_RS17275	COG0250	Participates in transcription elongation, termination and antitermination
I7V34_RS17280	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
I7V34_RS17285	COG0081	regulation of translation
I7V34_RS17290	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
I7V34_RS17295	COG0222	ribosome binding
I7V34_RS17300	COG2813	Specifically methylates the guanine in position
I7V34_RS17305	COG0085	RNA polymerase activity
I7V34_RS17315	COG1358	cellular component organization or biogenesis
I7V34_RS17320	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
I7V34_RS17325	COG0049	tRNA binding
I7V34_RS17330	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
I7V34_RS17335	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
I7V34_RS17345	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
I7V34_RS17350	COG0088	Forms part of the polypeptide exit tunnel
I7V34_RS17360	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
I7V34_RS17365	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
I7V34_RS17370	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
I7V34_RS17375	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
I7V34_RS17380	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
I7V34_RS17385	COG0255	Belongs to the universal ribosomal protein uL29 family
I7V34_RS17390	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
I7V34_RS17395	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
I7V34_RS17405	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
I7V34_RS17410	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
I7V34_RS17420	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
I7V34_RS17425	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
I7V34_RS17430	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
I7V34_RS17435	COG1841	ribosomal large subunit assembly
I7V34_RS17445	COG0201	protein transport
I7V34_RS17450	COG0563	adenylate kinase activity
I7V34_RS17455	COG0024	Methionine aminopeptidase
I7V34_RS17460	COG2163	COG2163 Ribosomal protein L14E L6E L27E
I7V34_RS17465	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
I7V34_RS17470	COG0257	Belongs to the bacterial ribosomal protein bL36 family
I7V34_RS17475	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
I7V34_RS17485	COG0202	RNA polymerase activity
I7V34_RS17490	COG0203	ribosomal protein L17
I7V34_RS17495	COG1122	ATPase activity
I7V34_RS17500	COG1122	ATPase activity
I7V34_RS17505	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
I7V34_RS17510	COG0101	tRNA pseudouridine synthase activity
I7V34_RS17515	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
I7V34_RS17520	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
I7V34_RS17540	COG0860	N-Acetylmuramoyl-L-alanine amidase
I7V34_RS17545	COG1366	Belongs to the anti-sigma-factor antagonist family
I7V34_RS17550	COG0489	protein tyrosine kinase activity
I7V34_RS17560	COG2194	sulfuric ester hydrolase activity
I7V34_RS17565	COG0726	polysaccharide deacetylase
I7V34_RS17650	COG1595	DNA-templated transcription, initiation
I7V34_RS17655	COG5662	AntiSigma factor
I7V34_RS17660	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
I7V34_RS17665	COG4856	YbbR-like protein
I7V34_RS17670	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
I7V34_RS17675	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
I7V34_RS17685	COG3403	YqcI/YcgG family
I7V34_RS17700	COG2340	Cysteine-rich secretory protein family
I7V34_RS17735	COG1028	Short-chain dehydrogenase reductase Sdr
I7V34_RS17745	COG2814	Major facilitator Superfamily
I7V34_RS17765	COG4585	Histidine kinase
I7V34_RS17770	COG2197	response regulator
I7V34_RS17775	COG1131	(ABC) transporter
I7V34_RS17790	COG1115	amino acid carrier protein
I7V34_RS17800	COG0517	IMP dehydrogenase activity
I7V34_RS17805	COG2340	Cysteine-rich secretory protein family
I7V34_RS17815	COG1597	lipid kinase activity
I7V34_RS17820	COG1238	metal cluster binding
I7V34_RS17825	COG0018	arginyl-trna synthetase
I7V34_RS17830	COG0772	Belongs to the SEDS family
I7V34_RS17845	COG0398	Pfam SNARE associated Golgi protein
I7V34_RS17855	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
I7V34_RS17860	COG1181	Belongs to the D-alanine--D-alanine ligase family
I7V34_RS17865	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
I7V34_RS17875	COG0513	Belongs to the DEAD box helicase family
I7V34_RS17885	COG4294	response to UV
I7V34_RS17890	COG3402	PFAM membrane-flanked domain
I7V34_RS17895	COG3428	Bacterial PH domain
I7V34_RS17900	COG0705	Rhomboid family
I7V34_RS17905	COG0736	holo-[acyl-carrier-protein] synthase activity
I7V34_RS17910	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
I7V34_RS17920	COG0864	Transcriptional regulator
I7V34_RS17925	COG2337	Toxic component of a toxin-antitoxin (TA) module
I7V34_RS17930	COG1366	Belongs to the anti-sigma-factor antagonist family
I7V34_RS17935	COG1366	Belongs to the anti-sigma-factor antagonist family
I7V34_RS17940	COG2172	sigma factor antagonist activity
I7V34_RS17945	COG2208	phosphoserine phosphatase activity
I7V34_RS17950	COG1366	Belongs to the anti-sigma-factor antagonist family
I7V34_RS17955	COG2172	sigma factor antagonist activity
I7V34_RS17960	COG1191	sigma factor activity
I7V34_RS17965	COG2208	phosphoserine phosphatase activity
I7V34_RS17970	COG2183	response to ionizing radiation
I7V34_RS17980	COG3091	SprT-like family
I7V34_RS18065	COG0802	atpase or kinase
I7V34_RS18070	COG1214	PFAM Peptidase M22, glycoprotease
I7V34_RS18075	COG0456	acetyltransferase
I7V34_RS18085	COG0488	(ABC) transporter
I7V34_RS18090	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
I7V34_RS18095	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
I7V34_RS18100	COG0805	protein transport
I7V34_RS18110	COG1266	CAAX protease self-immunity
I7V34_RS18120	COG0459	protein refolding
I7V34_RS18125	COG0582	viral genome integration into host DNA
I7V34_RS18200	COG1846	Transcriptional regulator
I7V34_RS18205	COG2814	Major facilitator Superfamily
I7V34_RS18225	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
I7V34_RS18260	COG2304	oxidoreductase activity
I7V34_RS18335	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
I7V34_RS18350	COG0714	Associated with various cellular activities
I7V34_RS18355	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
I7V34_RS18360	COG1305	Transglutaminase-like
I7V34_RS18365	COG0518	GMP synthase (glutamine-hydrolyzing) activity
I7V34_RS18365	COG0519	Catalyzes the synthesis of GMP from XMP
I7V34_RS18370	COG2252	PERMEase
I7V34_RS18375	COG3711	transcriptional antiterminator
I7V34_RS18380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I7V34_RS18380	COG1263	PTS System
I7V34_RS18380	COG2190	(PTS) system
I7V34_RS18405	COG2814	Major facilitator Superfamily
I7V34_RS18410	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
I7V34_RS18420	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
I7V34_RS18425	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
I7V34_RS18430	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
I7V34_RS18435	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
I7V34_RS18440	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
I7V34_RS18445	COG0047	phosphoribosylformylglycinamidine synthase activity
I7V34_RS18455	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
I7V34_RS18465	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
I7V34_RS18475	COG0151	Belongs to the GarS family
I7V34_RS18490	COG1470	cell adhesion involved in biofilm formation
I7V34_RS18495	COG4496	protein, YerC YecD
I7V34_RS18500	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
I7V34_RS18505	COG0210	DNA helicase
I7V34_RS18510	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
I7V34_RS18515	COG4851	CamS sex pheromone cAM373 precursor
I7V34_RS18525	COG2224	Isocitrate lyase
I7V34_RS18530	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
I7V34_RS18535	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
I7V34_RS18540	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
I7V34_RS18550	COG0505	Belongs to the CarA family
I7V34_RS18555	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
I7V34_RS18560	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
I7V34_RS18565	COG2304	oxidoreductase activity
I7V34_RS18575	COG5506	Protein of unknown function (DUF1694)
I7V34_RS18585	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
I7V34_RS18590	COG0154	amidase activity
I7V34_RS18640	COG1597	lipid kinase activity
I7V34_RS18670	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
I7V34_RS18680	COG0166	Belongs to the GPI family
I7V34_RS18685	COG4895	conserved protein (DUF2196)
I7V34_RS18690	COG1914	H( )-stimulated, divalent metal cation uptake system
I7V34_RS18695	COG1984	allophanate hydrolase subunit 2
I7V34_RS18700	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
I7V34_RS18705	COG2814	Major facilitator Superfamily
I7V34_RS18715	COG1595	DNA-templated transcription, initiation
I7V34_RS18725	COG1131	(ABC) transporter
I7V34_RS18730	COG1725	Transcriptional regulator
I7V34_RS18735	COG4555	ABC transporter
I7V34_RS18765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I7V34_RS18775	COG3859	Proton-coupled thiamine transporter YuaJ
I7V34_RS18780	COG2966	Psort location CytoplasmicMembrane, score
I7V34_RS18785	COG3610	response to peptide
I7V34_RS18795	COG1132	(ABC) transporter
I7V34_RS18800	COG1132	(ABC) transporter
I7V34_RS18805	COG3871	stress protein (general stress protein 26)
I7V34_RS18815	COG2323	membrane
I7V34_RS18825	COG1115	amino acid carrier protein
I7V34_RS18830	COG1960	acyl-CoA dehydrogenase activity
I7V34_RS18845	COG0584	glycerophosphoryl diester phosphodiesterase
I7V34_RS18870	COG2193	ferroxidase activity
I7V34_RS18880	COG1404	Belongs to the peptidase S8 family
I7V34_RS18885	COG2032	superoxide dismutase activity
I7V34_RS18890	COG0733	neurotransmitter:sodium symporter activity
I7V34_RS18895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
I7V34_RS18900	COG0488	(ABC) transporter
I7V34_RS18910	COG3396	Phenylacetate-CoA oxygenase
I7V34_RS18935	COG1024	Enoyl-CoA hydratase
I7V34_RS18940	COG1024	Enoyl-CoA hydratase
I7V34_RS18945	COG1012	belongs to the aldehyde dehydrogenase family
I7V34_RS18950	COG1250	3-hydroxyacyl-CoA dehydrogenase
I7V34_RS18955	COG0183	Belongs to the thiolase family
I7V34_RS18965	COG3327	negative regulation of DNA-templated transcription, initiation
I7V34_RS18970	COG2070	2-Nitropropane dioxygenase
I7V34_RS18980	COG4120	Belongs to the binding-protein-dependent transport system permease family
I7V34_RS18985	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
I7V34_RS19005	COG0022	dehydrogenase e1 component
I7V34_RS19020	COG3185	4-Hydroxyphenylpyruvate dioxygenase
I7V34_RS19025	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
I7V34_RS19030	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
I7V34_RS19035	COG0179	Fumarylacetoacetate (FAA) hydrolase
I7V34_RS19045	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
I7V34_RS19050	COG0129	dihydroxy-acid dehydratase activity
I7V34_RS19055	COG0028	Belongs to the TPP enzyme family
I7V34_RS19060	COG0440	acetolactate synthase activity
I7V34_RS19065	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
I7V34_RS19070	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
I7V34_RS19085	COG0066	3-isopropylmalate dehydratase activity
I7V34_RS19090	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
I7V34_RS19095	COG0460	homoserine dehydrogenase
I7V34_RS19100	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
I7V34_RS19105	COG0083	homoserine kinase activity
I7V34_RS19120	COG5002	protein histidine kinase activity
I7V34_RS19140	COG0210	DNA helicase
I7V34_RS19160	COG1737	Transcriptional regulator
I7V34_RS19165	COG2610	gluconate transmembrane transporter activity
I7V34_RS19170	COG1070	Carbohydrate kinase
I7V34_RS19195	COG2249	NAD(P)H dehydrogenase (quinone) activity
I7V34_RS19205	COG1968	undecaprenyl-diphosphatase activity
I7V34_RS19225	COG1309	transcriptional regulator
I7V34_RS19230	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
I7V34_RS19235	COG2244	polysaccharide biosynthetic process
I7V34_RS19280	COG4585	Histidine kinase
I7V34_RS19285	COG2197	response regulator
I7V34_RS19320	COG1714	RDD family
I7V34_RS19330	COG1012	belongs to the aldehyde dehydrogenase family
I7V34_RS19335	COG2130	NADP-dependent
I7V34_RS19350	COG0456	acetyltransferase
I7V34_RS19355	COG2814	Major facilitator Superfamily
I7V34_RS19370	COG0288	reversible hydration of carbon dioxide
I7V34_RS19385	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
I7V34_RS19395	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
I7V34_RS19405	COG0488	(ABC) transporter
I7V34_RS19410	COG2720	vancomycin resistance protein
I7V34_RS19420	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
I7V34_RS19430	COG2861	carbohydrate metabolic process
I7V34_RS19435	COG1473	amidohydrolase
I7V34_RS19440	COG1757	Na H antiporter
I7V34_RS19480	COG1595	DNA-templated transcription, initiation
I7V34_RS19485	COG1077	Cell shape determining protein MreB Mrl
I7V34_RS19490	COG0840	transmembrane signaling receptor activity
I7V34_RS19495	COG1744	ABC transporter substrate-binding protein PnrA-like
I7V34_RS19500	COG1607	acyl-coa hydrolase
I7V34_RS19505	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
I7V34_RS19525	COG2309	aminopeptidase activity
I7V34_RS19535	COG1959	2 iron, 2 sulfur cluster binding
I7V34_RS19580	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
I7V34_RS19585	COG1360	Flagellar Motor Protein
I7V34_RS19590	COG1115	amino acid carrier protein
I7V34_RS19595	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I7V34_RS19600	COG2313	pseudouridylate synthase activity
I7V34_RS19605	COG5002	protein histidine kinase activity
I7V34_RS19610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
I7V34_RS19615	COG0220	tRNA (guanine-N7-)-methyltransferase activity
I7V34_RS19620	COG3486	L-lysine 6-monooxygenase (NADPH) activity
I7V34_RS19625	COG0693	protein deglycase activity
I7V34_RS19630	COG4840	Belongs to the UPF0435 family
I7V34_RS19640	COG1295	ribonuclease BN
I7V34_RS19645	COG3275	phosphorelay sensor kinase activity
I7V34_RS19650	COG3279	Response regulator of the LytR AlgR family
I7V34_RS19655	COG0584	glycerophosphoryl diester phosphodiesterase
I7V34_RS19665	COG1966	Carbon starvation protein
I7V34_RS19680	COG1595	DNA-templated transcription, initiation
I7V34_RS19695	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
I7V34_RS19720	COG0069	glutamate synthase activity
I7V34_RS19730	COG1845	cytochrome c oxidase, subunit III
I7V34_RS19740	COG2010	Cytochrome c
I7V34_RS19740	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
I7V34_RS19745	COG0028	Belongs to the TPP enzyme family
I7V34_RS19755	COG2267	carboxylic ester hydrolase activity
I7V34_RS19780	COG2190	(PTS) system
I7V34_RS19780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I7V34_RS19780	COG1263	PTS System
I7V34_RS19790	COG2323	membrane
I7V34_RS19800	COG0778	Nitroreductase
I7V34_RS19805	COG1846	Transcriptional regulator
I7V34_RS19810	COG1733	regulation of RNA biosynthetic process
I7V34_RS19815	COG2814	Major facilitator Superfamily
I7V34_RS19835	COG2217	Heavy metal translocating P-type atpase
I7V34_RS19840	COG0477	Major facilitator Superfamily
I7V34_RS19850	COG3871	stress protein (general stress protein 26)
I7V34_RS19855	COG0387	Pfam Sodium calcium exchanger
I7V34_RS19875	COG0535	radical SAM domain protein
I7V34_RS19895	COG0494	nUDIX hydrolase
I7V34_RS19920	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
I7V34_RS19925	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
I7V34_RS19940	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
I7V34_RS19950	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
I7V34_RS20000	COG0653	protein targeting
I7V34_RS20025	COG2132	Multicopper oxidase
I7V34_RS20045	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
I7V34_RS20045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I7V34_RS20050	COG1309	transcriptional regulator
I7V34_RS20065	COG3773	Cell wall hydrolase
I7V34_RS20080	COG2259	Doxx family
I7V34_RS20090	COG1902	pentaerythritol trinitrate reductase activity
I7V34_RS20095	COG0861	Integral membrane protein TerC family
I7V34_RS20100	COG0488	(ABC) transporter
I7V34_RS20105	COG4912	Dna alkylation repair
I7V34_RS20115	COG1028	Short-chain dehydrogenase reductase Sdr
I7V34_RS20125	COG1131	(ABC) transporter
I7V34_RS20140	COG3634	alkyl hydroperoxide reductase activity
I7V34_RS20145	COG0450	alkyl hydroperoxide reductase
I7V34_RS20150	COG0019	diaminopimelate decarboxylase activity
I7V34_RS20155	COG0456	acetyltransferase
I7V34_RS20165	COG1280	lysine exporter protein (LysE YggA)
I7V34_RS20195	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
I7V34_RS20220	COG0697	spore germination
I7V34_RS20230	COG3655	Transcriptional regulator
I7V34_RS20235	COG3739	integral membrane protein
I7V34_RS20265	COG0482	sulfurtransferase activity
I7V34_RS20270	COG2706	6-phosphogluconolactonase activity
I7V34_RS20275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I7V34_RS20280	COG1063	alcohol dehydrogenase
I7V34_RS20300	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
I7V34_RS20345	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
I7V34_RS20350	COG1802	Transcriptional regulator
I7V34_RS20355	COG2084	Dehydrogenase
I7V34_RS20365	COG2610	gluconate transmembrane transporter activity
I7V34_RS20385	COG0456	acetyltransferase
I7V34_RS20390	COG2304	oxidoreductase activity
I7V34_RS20400	COG4336	lyase activity
I7V34_RS20405	COG2746	aminoglycoside 3-N-acetyltransferase activity
I7V34_RS20420	COG0745	RESPONSE REGULATOR receiver
I7V34_RS20425	COG3850	Histidine kinase
I7V34_RS20425	COG5002	protein histidine kinase activity
I7V34_RS20430	COG1136	(ABC) transporter
I7V34_RS20445	COG0477	Major facilitator Superfamily
I7V34_RS20535	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
I7V34_RS20540	COG2822	iron ion transport
I7V34_RS20545	COG2837	iron assimilation
I7V34_RS20550	COG0672	)-iron permease
I7V34_RS20560	COG2814	Major facilitator Superfamily
I7V34_RS20580	COG0395	ABC-type sugar transport system, permease component
I7V34_RS20590	COG2723	6-phospho-beta-galactosidase activity
I7V34_RS20620	COG0730	response to heat
I7V34_RS20625	COG4221	oxidoreductase activity
I7V34_RS20630	COG1012	belongs to the aldehyde dehydrogenase family
I7V34_RS20655	COG0745	RESPONSE REGULATOR receiver
I7V34_RS20660	COG2205	protein histidine kinase activity
I7V34_RS20665	COG1388	LysM domain
I7V34_RS20675	COG0861	Integral membrane protein TerC family
I7V34_RS20710	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
I7V34_RS20715	COG0254	rRNA binding
I7V34_RS20730	COG2814	Major facilitator Superfamily
I7V34_RS20735	COG1309	transcriptional regulator
I7V34_RS20740	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
I7V34_RS20750	COG3588	fructose-bisphosphate aldolase
I7V34_RS20755	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
I7V34_RS20770	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
I7V34_RS20780	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
I7V34_RS20795	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
I7V34_RS20800	COG0805	protein transport
I7V34_RS20805	COG3540	Alkaline phosphatase
I7V34_RS20830	COG1595	DNA-templated transcription, initiation
I7V34_RS20870	COG0572	uridine kinase
I7V34_RS20890	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
I7V34_RS20890	COG0456	acetyltransferase
I7V34_RS20910	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
I7V34_RS21015	COG1401	restriction endodeoxyribonuclease activity
I7V34_RS21025	COG0513	Belongs to the DEAD box helicase family
I7V34_RS21055	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
I7V34_RS21070	COG0305	Participates in initiation and elongation during chromosome replication
I7V34_RS21085	COG0542	response to heat
I7V34_RS21100	COG0697	spore germination
I7V34_RS21105	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
I7V34_RS21120	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
I7V34_RS21125	COG0640	Transcriptional regulator
I7V34_RS21140	COG1401	restriction endodeoxyribonuclease activity
I7V34_RS21175	COG5505	Protein of unknown function (DUF819)
I7V34_RS21190	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
I7V34_RS21195	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
I7V34_RS21200	COG3142	Participates in the control of copper homeostasis
I7V34_RS21205	COG1408	metallophosphoesterase
I7V34_RS21220	COG5577	PFAM Coat F domain
I7V34_RS21225	COG1063	alcohol dehydrogenase
I7V34_RS21235	COG5577	PFAM Coat F domain
I7V34_RS21245	COG4807	Protein conserved in bacteria
I7V34_RS21255	COG1136	(ABC) transporter
I7V34_RS21260	COG0577	efflux transmembrane transporter activity
I7V34_RS21270	COG5002	protein histidine kinase activity
I7V34_RS21275	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
I7V34_RS21280	COG1802	Transcriptional regulator
I7V34_RS21285	COG1804	L-carnitine dehydratase bile acid-inducible protein F
I7V34_RS21290	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
I7V34_RS21295	COG0066	3-isopropylmalate dehydratase activity
I7V34_RS21305	COG4145	pantothenate transmembrane transporter activity
I7V34_RS21310	COG2271	Major facilitator Superfamily
I7V34_RS21315	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
I7V34_RS21330	COG1024	Enoyl-CoA hydratase
I7V34_RS21335	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
I7V34_RS21370	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
I7V34_RS21380	COG1028	Short-chain dehydrogenase reductase Sdr
I7V34_RS21390	COG1366	Belongs to the anti-sigma-factor antagonist family
I7V34_RS21480	COG3708	Transcriptional regulator
I7V34_RS21480	COG2207	Transcriptional regulator
I7V34_RS21505	COG0494	nUDIX hydrolase
I7V34_RS21585	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
I7V34_RS21590	COG1595	DNA-templated transcription, initiation
I7V34_RS21610	COG1301	dicarboxylic acid transport
I7V34_RS21620	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
I7V34_RS21655	COG1233	COG1233 Phytoene dehydrogenase and related
I7V34_RS21670	COG1595	DNA-templated transcription, initiation
I7V34_RS21685	COG1595	DNA-templated transcription, initiation
I7V34_RS21715	COG2508	Transcriptional regulator
I7V34_RS21720	COG1012	belongs to the aldehyde dehydrogenase family
I7V34_RS21725	COG0506	proline dehydrogenase activity
I7V34_RS21730	COG1720	tRNA m6t6A37 methyltransferase activity
I7V34_RS21740	COG2267	carboxylic ester hydrolase activity
I7V34_RS21745	COG1595	DNA-templated transcription, initiation
I7V34_RS21775	COG0494	nUDIX hydrolase
I7V34_RS21790	COG0456	acetyltransferase
I7V34_RS21790	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
I7V34_RS21830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I7V34_RS21835	COG2188	Transcriptional regulator
I7V34_RS21855	COG1263	PTS System
I7V34_RS21855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I7V34_RS21860	COG1253	flavin adenine dinucleotide binding
I7V34_RS21865	COG0628	permease
I7V34_RS21870	COG1846	Transcriptional regulator
I7V34_RS21925	COG0346	lactoylglutathione lyase activity
I7V34_RS21935	COG2814	Major facilitator Superfamily
I7V34_RS21940	COG0671	phosphoesterase, PA-phosphatase related
I7V34_RS21955	COG2084	Dehydrogenase
I7V34_RS21960	COG0366	Alpha amylase catalytic
I7V34_RS22000	COG1131	(ABC) transporter
I7V34_RS22020	COG0501	Belongs to the peptidase M48B family
I7V34_RS22025	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
I7V34_RS22030	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
I7V34_RS22035	COG1028	Short-chain dehydrogenase reductase Sdr
I7V34_RS22040	COG3706	GGDEF domain
I7V34_RS22045	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
I7V34_RS22055	COG2814	Major facilitator Superfamily
I7V34_RS22060	COG1309	transcriptional regulator
I7V34_RS22070	COG1278	Cold shock
I7V34_RS22110	COG3239	Fatty acid desaturase
I7V34_RS22115	COG0306	phosphate transporter
I7V34_RS22120	COG1392	Phosphate transport regulator
I7V34_RS22125	COG2207	Transcriptional regulator
I7V34_RS22125	COG3708	Transcriptional regulator
I7V34_RS22140	COG0789	Transcriptional regulator