locus-tag	class	description
QF06_RS00015	COG0531	amino acid
QF06_RS00020	COG0584	glycerophosphoryl diester phosphodiesterase
QF06_RS00035	COG1846	Transcriptional regulator
QF06_RS00035	COG0456	acetyltransferase
QF06_RS00040	COG2271	Major facilitator Superfamily
QF06_RS00050	COG3409	Peptidoglycan-binding domain 1 protein
QF06_RS00055	COG0697	spore germination
QF06_RS00060	COG2207	Transcriptional regulator
QF06_RS00060	COG1917	Cupin 2, conserved barrel domain protein
QF06_RS00065	COG1397	ADP-ribosylglycohydrolase
QF06_RS00070	COG5444	nuclease activity
QF06_RS00075	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
QF06_RS00080	COG3591	Belongs to the peptidase S1B family
QF06_RS00090	COG0596	Alpha beta hydrolase
QF06_RS00095	COG1183	phosphatidylcholine synthase activity
QF06_RS00100	COG0586	Pfam SNARE associated Golgi protein
QF06_RS00105	COG0688	phosphatidylethanolamine metabolic process
QF06_RS00115	COG2312	Erythromycin esterase
QF06_RS00120	COG1054	Belongs to the UPF0176 family
QF06_RS00125	COG1301	dicarboxylic acid transport
QF06_RS00130	COG1263	PTS System
QF06_RS00130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
QF06_RS00130	COG2190	(PTS) system
QF06_RS00135	COG0363	glucosamine-6-phosphate deaminase activity
QF06_RS00140	COG2188	Transcriptional regulator
QF06_RS00145	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
QF06_RS00150	COG0833	amino acid
QF06_RS00155	COG2040	homocysteine
QF06_RS00165	COG1115	amino acid carrier protein
QF06_RS00170	COG2066	Belongs to the glutaminase family
QF06_RS00175	COG4191	Histidine kinase
QF06_RS00180	COG0784	Response regulator, receiver
QF06_RS00185	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
QF06_RS00190	COG1012	belongs to the aldehyde dehydrogenase family
QF06_RS00195	COG2271	Major facilitator Superfamily
QF06_RS00200	COG4948	Mandelate Racemase Muconate Lactonizing
QF06_RS00205	COG2186	Transcriptional regulator
QF06_RS00210	COG2721	sulfolactate sulfo-lyase activity
QF06_RS00215	COG3173	Aminoglycoside phosphotransferase
QF06_RS00225	COG0697	spore germination
QF06_RS00230	COG0745	RESPONSE REGULATOR receiver
QF06_RS00235	COG2205	protein histidine kinase activity
QF06_RS00240	COG1131	(ABC) transporter
QF06_RS00255	COG3773	Cell wall hydrolase
QF06_RS00260	COG2304	oxidoreductase activity
QF06_RS00265	COG3540	Alkaline phosphatase
QF06_RS00270	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
QF06_RS00275	COG0805	protein transport
QF06_RS00280	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
QF06_RS00285	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
QF06_RS00290	COG0477	Major facilitator Superfamily
QF06_RS00295	COG1309	transcriptional regulator
QF06_RS00300	COG0252	asparaginase activity
QF06_RS00305	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
QF06_RS00310	COG1714	RDD family
QF06_RS00315	COG3012	SEC-C Motif Domain Protein
QF06_RS00315	COG1405	negative regulation of cell septum assembly
QF06_RS00320	COG3290	protein histidine kinase activity
QF06_RS00325	COG3279	Response regulator of the LytR AlgR family
QF06_RS00330	COG4555	ABC transporter
QF06_RS00335	COG1668	transmembrane transport
QF06_RS00340	COG0667	Aldo Keto reductase
QF06_RS00350	COG1595	DNA-templated transcription, initiation
QF06_RS00355	COG1595	DNA-templated transcription, initiation
QF06_RS00360	COG1876	peptidase activity
QF06_RS00365	COG0457	Tetratricopeptide repeat
QF06_RS00370	COG1028	Short-chain dehydrogenase reductase Sdr
QF06_RS00375	COG0366	Alpha amylase catalytic
QF06_RS00380	COG0803	Belongs to the bacterial solute-binding protein 9 family
QF06_RS00385	COG1121	(ABC) transporter
QF06_RS00390	COG1108	ABC-type Mn2 Zn2 transport systems permease components
QF06_RS00395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
QF06_RS00400	COG2310	stress, protein
QF06_RS00405	COG2310	stress, protein
QF06_RS00410	COG2310	stress, protein
QF06_RS00415	COG0861	Integral membrane protein TerC family
QF06_RS00425	COG3853	Toxic anion resistance protein (TelA)
QF06_RS00430	COG0477	Major facilitator Superfamily
QF06_RS00435	COG2814	Major facilitator Superfamily
QF06_RS00440	COG0640	Transcriptional regulator
QF06_RS00445	COG0517	IMP dehydrogenase activity
QF06_RS00445	COG4175	Glycine betaine
QF06_RS00450	COG4176	ABC-type proline glycine betaine transport system permease component
QF06_RS00455	COG2113	Glycine betaine
QF06_RS00460	COG1473	amidohydrolase
QF06_RS00465	COG1288	antiporter activity
QF06_RS00475	COG0366	Alpha amylase catalytic
QF06_RS00480	COG0039	L-malate dehydrogenase activity
QF06_RS00485	COG1620	l-lactate permease
QF06_RS00490	COG2814	Major facilitator Superfamily
QF06_RS00495	COG1846	Transcriptional regulator
QF06_RS00500	COG1280	lysine exporter protein (LysE YggA)
QF06_RS00505	COG3403	YqcI/YcgG family
QF06_RS00510	COG1113	amino acid transport
QF06_RS00515	COG3665	Urea carboxylase-associated protein
QF06_RS00520	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
QF06_RS00525	COG1660	Displays ATPase and GTPase activities
QF06_RS00530	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
QF06_RS00535	COG2226	methyltransferase
QF06_RS00540	COG0583	DNA-binding transcription factor activity
QF06_RS00545	COG3458	cephalosporin-C deacetylase activity
QF06_RS00550	COG3541	Predicted nucleotidyltransferase
QF06_RS00560	COG1012	belongs to the aldehyde dehydrogenase family
QF06_RS00565	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
QF06_RS00570	COG2508	Transcriptional regulator
QF06_RS00575	COG3689	TIGRFAM TIGR03943 family protein
QF06_RS00580	COG0701	Predicted permease
QF06_RS00585	COG2267	carboxylic ester hydrolase activity
QF06_RS00590	COG0492	ferredoxin-NADP+ reductase activity
QF06_RS00595	COG1587	Uroporphyrinogen-III synthase
QF06_RS00595	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
QF06_RS00600	COG2146	nitrite reductase [NAD(P)H] activity
QF06_RS00605	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
QF06_RS00610	COG0243	molybdopterin cofactor binding
QF06_RS00615	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
QF06_RS00620	COG2223	nitrite transmembrane transporter activity
QF06_RS00625	COG1469	GTP cyclohydrolase I activity
QF06_RS00630	COG1376	ErfK ybiS ycfS ynhG family protein
QF06_RS00635	COG0523	cobalamin synthesis protein
QF06_RS00640	COG0765	amino acid transport
QF06_RS00645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
QF06_RS00655	COG1714	RDD family
QF06_RS00665	COG2723	6-phospho-beta-galactosidase activity
QF06_RS00675	COG3209	COG3209 Rhs family protein
QF06_RS00680	COG0840	transmembrane signaling receptor activity
QF06_RS00680	COG3290	protein histidine kinase activity
QF06_RS00685	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
QF06_RS00690	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
QF06_RS00695	COG1733	regulation of RNA biosynthetic process
QF06_RS00700	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
QF06_RS00705	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
QF06_RS00710	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
QF06_RS00715	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
QF06_RS00720	COG2814	Major facilitator Superfamily
QF06_RS00730	COG0697	spore germination
QF06_RS00735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
QF06_RS00745	COG2364	Membrane
QF06_RS00750	COG1126	abc transporter atp-binding protein
QF06_RS00755	COG0765	amino acid transport
QF06_RS00760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
QF06_RS00765	COG0583	DNA-binding transcription factor activity
QF06_RS00770	COG0163	prenyltransferase activity
QF06_RS00775	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
QF06_RS00790	COG0596	Alpha beta hydrolase
QF06_RS00795	COG3104	oligopeptide transport
QF06_RS00800	COG5434	Belongs to the glycosyl hydrolase 28 family
QF06_RS00810	COG0697	spore germination
QF06_RS00820	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
QF06_RS00825	COG1136	(ABC) transporter
QF06_RS00830	COG0577	efflux transmembrane transporter activity
QF06_RS00835	COG0745	RESPONSE REGULATOR receiver
QF06_RS00840	COG5002	protein histidine kinase activity
QF06_RS00840	COG3850	Histidine kinase
QF06_RS00845	COG0457	Tetratricopeptide repeat
QF06_RS00865	COG0527	aspartate kinase activity
QF06_RS00870	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
QF06_RS00875	COG4605	iron ion homeostasis
QF06_RS00880	COG4604	ABC transporter, ATP-binding protein
QF06_RS00885	COG4607	ABC-type enterochelin transport system periplasmic component
QF06_RS00890	COG2814	Major facilitator Superfamily
QF06_RS00895	COG1309	transcriptional regulator
QF06_RS00900	COG0778	Nitroreductase
QF06_RS00905	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
QF06_RS00910	COG0640	Transcriptional regulator
QF06_RS00915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
QF06_RS00920	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
QF06_RS00925	COG1012	belongs to the aldehyde dehydrogenase family
QF06_RS00930	COG4975	Glucose uptake
QF06_RS00935	COG1028	Short-chain dehydrogenase reductase Sdr
QF06_RS00940	COG4549	nuclear export factor GLE1
QF06_RS00945	COG2372	response to copper ion
QF06_RS00945	COG1276	copper resistance
QF06_RS00950	COG1349	DNA-binding transcription factor activity
QF06_RS00960	COG2213	PTS system mannitol-specific
QF06_RS00965	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
QF06_RS00970	COG0246	Mannitol dehydrogenase
QF06_RS00975	COG0473	3-isopropylmalate dehydrogenase activity
QF06_RS00980	COG0681	Belongs to the peptidase S26 family
QF06_RS00985	COG0412	Dienelactone hydrolase
QF06_RS00990	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
QF06_RS00995	COG0561	phosphatase activity
QF06_RS01000	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
QF06_RS01005	COG1914	H( )-stimulated, divalent metal cation uptake system
QF06_RS01010	COG4336	lyase activity
QF06_RS01015	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
QF06_RS01020	COG1984	allophanate hydrolase subunit 2
QF06_RS01025	COG1414	Transcriptional regulator
QF06_RS01030	COG2755	lipolytic protein G-D-S-L family
QF06_RS01040	COG2329	Antibiotic biosynthesis monooxygenase
QF06_RS01045	COG0768	penicillin binding
QF06_RS01050	COG4989	oxidoreductase activity
QF06_RS01055	COG3711	transcriptional antiterminator
QF06_RS01060	COG0318	PFAM AMP-dependent synthetase and ligase
QF06_RS01065	COG2226	methyltransferase
QF06_RS01070	COG1028	Short-chain dehydrogenase reductase Sdr
QF06_RS01075	COG1917	Cupin 2, conserved barrel domain protein
QF06_RS01080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
QF06_RS01085	COG3871	stress protein (general stress protein 26)
QF06_RS01095	COG2814	Major facilitator Superfamily
QF06_RS01100	COG1522	sequence-specific DNA binding
QF06_RS01105	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
QF06_RS01105	COG0551	DNA topoisomerase type I activity
QF06_RS01110	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
QF06_RS01115	COG3706	GGDEF domain
QF06_RS01120	COG5298	Protein conserved in bacteria
QF06_RS01125	COG1215	transferase activity, transferring glycosyl groups
QF06_RS01135	COG0531	amino acid
QF06_RS01140	COG0494	nUDIX hydrolase
QF06_RS01145	COG0028	Belongs to the TPP enzyme family
QF06_RS01155	COG1914	H( )-stimulated, divalent metal cation uptake system
QF06_RS01160	COG2261	transglycosylase associated protein
QF06_RS01165	COG4876	unkown
QF06_RS01170	COG2217	Heavy metal translocating P-type atpase
QF06_RS01175	COG3729	General stress protein
QF06_RS01180	COG0662	Cupin 2, conserved barrel domain protein
QF06_RS01185	COG2329	Antibiotic biosynthesis monooxygenase
QF06_RS01190	COG3546	catalase activity
QF06_RS01195	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
QF06_RS01200	COG3290	protein histidine kinase activity
QF06_RS01205	COG4565	transcriptional regulatory protein
QF06_RS01210	COG1301	dicarboxylic acid transport
QF06_RS01215	COG0628	permease
QF06_RS01220	COG1131	(ABC) transporter
QF06_RS01225	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
QF06_RS01235	COG1960	acyl-CoA dehydrogenase activity
QF06_RS01240	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
QF06_RS01245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
QF06_RS01250	COG1181	Belongs to the D-alanine--D-alanine ligase family
QF06_RS01255	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
QF06_RS01260	COG0513	Belongs to the DEAD box helicase family
QF06_RS01265	COG3402	PFAM membrane-flanked domain
QF06_RS01270	COG3428	Bacterial PH domain
QF06_RS01275	COG0705	Rhomboid family
QF06_RS01280	COG0736	holo-[acyl-carrier-protein] synthase activity
QF06_RS01285	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
QF06_RS01290	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
QF06_RS01295	COG0864	Transcriptional regulator
QF06_RS01300	COG2337	Toxic component of a toxin-antitoxin (TA) module
QF06_RS01305	COG1366	Belongs to the anti-sigma-factor antagonist family
QF06_RS01310	COG1366	Belongs to the anti-sigma-factor antagonist family
QF06_RS01315	COG2172	sigma factor antagonist activity
QF06_RS01320	COG2208	phosphoserine phosphatase activity
QF06_RS01325	COG1366	Belongs to the anti-sigma-factor antagonist family
QF06_RS01330	COG2172	sigma factor antagonist activity
QF06_RS01335	COG1191	sigma factor activity
QF06_RS01340	COG2208	phosphoserine phosphatase activity
QF06_RS01345	COG2183	response to ionizing radiation
QF06_RS01350	COG3091	SprT-like family
QF06_RS01390	COG0582	viral genome integration into host DNA
QF06_RS01405	COG0457	Tetratricopeptide repeat
QF06_RS01425	COG5444	nuclease activity
QF06_RS01435	COG1476	TRANSCRIPTIONal
QF06_RS01445	COG3239	Fatty acid desaturase
QF06_RS01450	COG1278	Cold shock
QF06_RS01455	COG1329	Transcriptional regulator
QF06_RS01460	COG0697	spore germination
QF06_RS01465	COG2207	Transcriptional regulator
QF06_RS01465	COG1917	Cupin 2, conserved barrel domain protein
QF06_RS01470	COG0697	spore germination
QF06_RS01475	COG3708	Transcriptional regulator
QF06_RS01475	COG2207	Transcriptional regulator
QF06_RS01480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
QF06_RS01485	COG0477	Major facilitator Superfamily
QF06_RS01495	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
QF06_RS01510	COG1309	transcriptional regulator
QF06_RS01515	COG0697	spore germination
QF06_RS01520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
QF06_RS01525	COG2030	dehydratase
QF06_RS01530	COG3545	Serine hydrolase
QF06_RS01535	COG1733	regulation of RNA biosynthetic process
QF06_RS01540	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
QF06_RS01545	COG1733	regulation of RNA biosynthetic process
QF06_RS01550	COG2249	NAD(P)H dehydrogenase (quinone) activity
QF06_RS01555	COG2814	Major facilitator Superfamily
QF06_RS01560	COG1309	transcriptional regulator
QF06_RS01565	COG0640	Transcriptional regulator
QF06_RS01570	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
QF06_RS01575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
QF06_RS01580	COG0697	spore germination
QF06_RS01585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
QF06_RS01590	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
QF06_RS01595	COG0640	Transcriptional regulator
QF06_RS01600	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
QF06_RS01610	COG4585	Histidine kinase
QF06_RS01615	COG2197	response regulator
QF06_RS01620	COG2409	Drug exporters of the RND superfamily
QF06_RS01625	COG0596	Alpha beta hydrolase
QF06_RS01630	COG1811	Na channel or pump
QF06_RS01635	COG0789	Transcriptional regulator
QF06_RS01635	COG4978	Transcriptional regulator
QF06_RS01640	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
QF06_RS01645	COG0778	Nitroreductase
QF06_RS01650	COG0346	lactoylglutathione lyase activity
QF06_RS01655	COG2259	Doxx family
QF06_RS01660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
QF06_RS01685	COG2323	membrane
QF06_RS01690	COG2323	membrane
QF06_RS01695	COG0071	Belongs to the small heat shock protein (HSP20) family
QF06_RS01710	COG1309	transcriptional regulator
QF06_RS01720	COG0456	acetyltransferase
QF06_RS01725	COG0488	(ABC) transporter
QF06_RS01730	COG1113	amino acid transport
QF06_RS01735	COG2318	DinB family
QF06_RS01740	COG1846	Transcriptional regulator
QF06_RS01745	COG1033	growth of symbiont in host cell
QF06_RS01745	COG2409	Drug exporters of the RND superfamily
QF06_RS01750	COG0778	Nitroreductase
QF06_RS01755	COG1846	Transcriptional regulator
QF06_RS01760	COG2814	Major facilitator Superfamily
QF06_RS01765	COG0730	response to heat
QF06_RS01770	COG1802	Transcriptional regulator
QF06_RS01775	COG3858	chitin binding
QF06_RS01775	COG1388	LysM domain
QF06_RS01780	COG1819	glycosyl
QF06_RS01790	COG1785	Belongs to the alkaline phosphatase family
QF06_RS01795	COG5646	InterPro IPR014922
QF06_RS01805	COG0454	-acetyltransferase
QF06_RS01810	COG1078	dGTPase activity
QF06_RS01815	COG1388	LysM domain
QF06_RS01820	COG2814	Major facilitator Superfamily
QF06_RS01825	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
QF06_RS01830	COG1447	Phosphotransferase system cellobiose-specific component IIA
QF06_RS01835	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
QF06_RS01840	COG2723	6-phospho-beta-galactosidase activity
QF06_RS01845	COG2188	Transcriptional regulator
QF06_RS01850	COG1940	carbohydrate kinase activity
QF06_RS01855	COG1482	cell wall glycoprotein biosynthetic process
QF06_RS01860	COG4124	Belongs to the glycosyl hydrolase 26 family
QF06_RS01905	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
QF06_RS01910	COG0802	atpase or kinase
QF06_RS01915	COG1214	PFAM Peptidase M22, glycoprotease
QF06_RS01920	COG0456	acetyltransferase
QF06_RS01925	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
QF06_RS01930	COG0488	(ABC) transporter
QF06_RS01935	COG0315	cyclic pyranopterin monophosphate synthase activity
QF06_RS01940	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
QF06_RS01945	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
QF06_RS01950	COG0805	protein transport
QF06_RS01960	COG1266	CAAX protease self-immunity
QF06_RS01970	COG0459	protein refolding
QF06_RS01975	COG1073	alpha beta
QF06_RS01980	COG0457	Tetratricopeptide repeat
QF06_RS01985	COG1063	alcohol dehydrogenase
QF06_RS01990	COG2211	Major facilitator Superfamily
QF06_RS01995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
QF06_RS02000	COG1842	Phage shock protein A
QF06_RS02005	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
QF06_RS02010	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
QF06_RS02015	COG4260	virion core protein, lumpy skin disease virus
QF06_RS02025	COG2814	Major facilitator Superfamily
QF06_RS02030	COG1063	alcohol dehydrogenase
QF06_RS02035	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
QF06_RS02040	COG0823	Involved in the tonB-independent uptake of proteins
QF06_RS02055	COG2267	carboxylic ester hydrolase activity
QF06_RS02065	COG2132	Multicopper oxidase
QF06_RS02070	COG1113	amino acid transport
QF06_RS02075	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
QF06_RS02080	COG0714	Associated with various cellular activities
QF06_RS02085	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
QF06_RS02090	COG1305	Transglutaminase-like
QF06_RS02095	COG0518	GMP synthase (glutamine-hydrolyzing) activity
QF06_RS02095	COG0519	Catalyzes the synthesis of GMP from XMP
QF06_RS02110	COG2252	PERMEase
QF06_RS02115	COG3064	Membrane
QF06_RS02120	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
QF06_RS02130	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
QF06_RS02135	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
QF06_RS02140	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
QF06_RS02145	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
QF06_RS02150	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
QF06_RS02155	COG0047	phosphoribosylformylglycinamidine synthase activity
QF06_RS02160	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
QF06_RS02165	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
QF06_RS02170	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
QF06_RS02175	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
QF06_RS02180	COG0138	bifunctional purine biosynthesis protein purh
QF06_RS02185	COG0151	Belongs to the GarS family
QF06_RS02190	COG1522	sequence-specific DNA binding
QF06_RS02195	COG0531	amino acid
QF06_RS02205	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
QF06_RS02210	COG1470	cell adhesion involved in biofilm formation
QF06_RS02215	COG4496	protein, YerC YecD
QF06_RS02220	COG0069	glutamate synthase activity
QF06_RS02225	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
QF06_RS02230	COG0210	DNA helicase
QF06_RS02235	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
QF06_RS02240	COG4851	CamS sex pheromone cAM373 precursor
QF06_RS02245	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
QF06_RS02250	COG1285	pathogenesis
QF06_RS02255	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
QF06_RS02260	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
QF06_RS02265	COG0154	amidase activity
QF06_RS02270	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
QF06_RS02275	COG1309	transcriptional regulator
QF06_RS02280	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
QF06_RS02285	COG1597	lipid kinase activity
QF06_RS02290	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
QF06_RS02305	COG5444	nuclease activity
QF06_RS02310	COG3391	amine dehydrogenase activity
QF06_RS02315	COG0457	Tetratricopeptide repeat
QF06_RS02325	COG0217	transcriptional regulatory protein
QF06_RS02335	COG1309	transcriptional regulator
QF06_RS02340	COG3631	Ketosteroid isomerase-related protein
QF06_RS02345	COG0702	epimerase
QF06_RS02360	COG3546	catalase activity
QF06_RS02365	COG0454	-acetyltransferase
QF06_RS02375	COG5578	integral membrane protein
QF06_RS02380	COG2972	Histidine kinase
QF06_RS02385	COG2207	Transcriptional regulator
QF06_RS02385	COG4753	response regulator
QF06_RS02390	COG1653	transport
QF06_RS02395	COG1175	transmembrane transport
QF06_RS02400	COG0395	ABC-type sugar transport system, permease component
QF06_RS02405	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
QF06_RS02410	COG2207	Transcriptional regulator
QF06_RS02415	COG2755	lipolytic protein G-D-S-L family
QF06_RS02425	COG5578	integral membrane protein
QF06_RS02430	COG3401	FG-GAP repeat protein
QF06_RS02435	COG3401	FG-GAP repeat protein
QF06_RS02440	COG2755	lipolytic protein G-D-S-L family
QF06_RS02445	COG1874	Beta-galactosidase
QF06_RS02455	COG1653	transport
QF06_RS02460	COG4209	transmembrane transport
QF06_RS02465	COG0395	ABC-type sugar transport system, permease component
QF06_RS02470	COG1486	melibiose metabolic process
QF06_RS02475	COG2323	membrane
QF06_RS02480	COG2329	Antibiotic biosynthesis monooxygenase
QF06_RS02485	COG0346	lactoylglutathione lyase activity
QF06_RS02500	COG0670	Belongs to the BI1 family
QF06_RS02505	COG0697	spore germination
QF06_RS02510	COG1846	Transcriptional regulator
QF06_RS02515	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
QF06_RS02530	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
QF06_RS02530	COG2124	cytochrome p450
QF06_RS02535	COG1368	sulfuric ester hydrolase activity
QF06_RS02540	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
QF06_RS02545	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
QF06_RS02550	COG1442	glycosyl transferase family 8
QF06_RS02555	COG1216	Glycosyl transferase, family 2
QF06_RS02560	COG1442	glycosyl transferase family 8
QF06_RS02565	COG2223	nitrite transmembrane transporter activity
QF06_RS02570	COG1011	Hydrolase
QF06_RS02575	COG0531	amino acid
QF06_RS02580	COG1012	belongs to the aldehyde dehydrogenase family
QF06_RS02585	COG0840	transmembrane signaling receptor activity
QF06_RS02590	COG0488	(ABC) transporter
QF06_RS02600	COG0789	Transcriptional regulator
QF06_RS02605	COG2814	Major facilitator Superfamily
QF06_RS02610	COG1404	Belongs to the peptidase S8 family
QF06_RS02625	COG0488	(ABC) transporter
QF06_RS02630	COG0513	Belongs to the DEAD box helicase family
QF06_RS02635	COG0456	acetyltransferase
QF06_RS02640	COG2130	NADP-dependent
QF06_RS02645	COG1120	ATPase activity
QF06_RS02650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
QF06_RS02655	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
QF06_RS02660	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
QF06_RS02675	COG3866	Pectate lyase
QF06_RS02680	COG0471	metal ion transport
QF06_RS02685	COG3290	protein histidine kinase activity
QF06_RS02690	COG4565	transcriptional regulatory protein
QF06_RS02695	COG3181	Tripartite tricarboxylate transporter family receptor
QF06_RS02700	COG2851	Citrate transporter
QF06_RS02705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
QF06_RS02710	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
QF06_RS02715	COG1254	Belongs to the acylphosphatase family
QF06_RS02720	COG2258	MOSC domain
QF06_RS02730	COG0024	Methionine aminopeptidase
QF06_RS02735	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
QF06_RS02735	COG1263	PTS System
QF06_RS02740	COG1368	sulfuric ester hydrolase activity
QF06_RS02750	COG1115	amino acid carrier protein
QF06_RS02755	COG0531	amino acid
QF06_RS02770	COG0697	spore germination
QF06_RS02775	COG1263	PTS System
QF06_RS02775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
QF06_RS02780	COG0366	Alpha amylase catalytic
QF06_RS02785	COG2188	Transcriptional regulator
QF06_RS02790	COG0778	Nitroreductase
QF06_RS02795	COG0737	Belongs to the 5'-nucleotidase family
QF06_RS02800	COG0693	protein deglycase activity
QF06_RS02805	COG2814	Major facilitator Superfamily
QF06_RS02810	COG4840	Belongs to the UPF0435 family
QF06_RS02815	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
QF06_RS02820	COG4980	gas vesicle protein
QF06_RS02825	COG1295	ribonuclease BN
QF06_RS02830	COG0477	Major facilitator Superfamily
QF06_RS02835	COG0387	Pfam Sodium calcium exchanger
QF06_RS02845	COG0668	transmembrane transport
QF06_RS02850	COG0535	radical SAM domain protein
QF06_RS02860	COG0726	polysaccharide deacetylase
QF06_RS02865	COG2084	Dehydrogenase
QF06_RS02870	COG0598	Magnesium transport protein CorA
QF06_RS02875	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
QF06_RS02880	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
QF06_RS02890	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
QF06_RS02895	COG4637	Psort location Cytoplasmic, score
QF06_RS02900	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
QF06_RS02905	COG0022	dehydrogenase e1 component
QF06_RS02910	COG0508	dehydrogenase complex catalyzes the overall conversion of
QF06_RS02915	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
QF06_RS02920	COG3284	Transcriptional regulator
QF06_RS02930	COG1742	UPF0060 membrane protein
QF06_RS02955	COG4842	Belongs to the WXG100 family
QF06_RS02960	COG1486	melibiose metabolic process
QF06_RS02965	COG1737	Transcriptional regulator
QF06_RS02970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
QF06_RS02970	COG1263	PTS System
QF06_RS02975	COG5434	Belongs to the glycosyl hydrolase 28 family
QF06_RS02980	COG1132	(ABC) transporter
QF06_RS02985	COG1132	(ABC) transporter
QF06_RS02990	COG2259	Doxx family
QF06_RS02995	COG2514	catechol 2,3-dioxygenase activity
QF06_RS03000	COG4585	Histidine kinase
QF06_RS03005	COG2197	response regulator
QF06_RS03010	COG1131	(ABC) transporter
QF06_RS03015	COG0842	Transport permease protein
QF06_RS03015	COG1511	domain protein
QF06_RS03020	COG0842	Transport permease protein
QF06_RS03025	COG1695	Transcriptional regulator
QF06_RS03030	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
QF06_RS03035	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
QF06_RS03040	COG2318	DinB family
QF06_RS03045	COG2814	Major facilitator Superfamily
QF06_RS03050	COG1846	Transcriptional regulator
QF06_RS03055	COG0392	lysyltransferase activity
QF06_RS03055	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
QF06_RS03060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
QF06_RS03065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
QF06_RS03070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
QF06_RS03075	COG0384	phenazine biosynthesis protein PhzF
QF06_RS03080	COG0778	Nitroreductase
QF06_RS03090	COG1090	epimerase
QF06_RS03095	COG2137	regulation of response to DNA damage stimulus
QF06_RS03105	COG2814	Major facilitator Superfamily
QF06_RS03120	COG3103	Sh3 type 3 domain protein
QF06_RS03125	COG5658	integral membrane protein
QF06_RS03130	COG0596	Alpha beta hydrolase
QF06_RS03135	COG0463	Glycosyl transferase, family 2
QF06_RS03140	COG4485	Bacterial membrane protein, YfhO
QF06_RS03145	COG1988	membrane-bound metal-dependent
QF06_RS03150	COG1194	a g-specific adenine glycosylase
QF06_RS03160	COG1028	Short-chain dehydrogenase reductase Sdr
QF06_RS03175	COG3557	Belongs to the UPF0374 family
QF06_RS03180	COG1132	(ABC) transporter
QF06_RS03185	COG4129	membrane
QF06_RS03190	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
QF06_RS03195	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
QF06_RS03200	COG0735	belongs to the Fur family
QF06_RS03310	COG4326	sporulation control protein
QF06_RS03325	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
QF06_RS03340	COG0753	catalase activity
QF06_RS03345	COG1116	anion transmembrane transporter activity
QF06_RS03350	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
QF06_RS03355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
QF06_RS03360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
QF06_RS03370	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
QF06_RS03380	COG1476	TRANSCRIPTIONal
QF06_RS03390	COG3382	B3 4 domain protein
QF06_RS03395	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
QF06_RS03405	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
QF06_RS03410	COG0789	Transcriptional regulator
QF06_RS03415	COG1664	Polymer-forming cytoskeletal
QF06_RS03420	COG1664	Polymer-forming cytoskeletal
QF06_RS03425	COG2766	serine protein kinase
QF06_RS03430	COG2718	Belongs to the UPF0229 family
QF06_RS03435	COG1846	Transcriptional regulator
QF06_RS03440	COG1566	PFAM secretion protein HlyD family protein
QF06_RS03445	COG2814	Major facilitator Superfamily
QF06_RS03450	COG0655	NAD(P)H dehydrogenase (quinone) activity
QF06_RS03465	COG1725	Transcriptional regulator
QF06_RS03470	COG1131	(ABC) transporter
QF06_RS03475	COG1131	(ABC) transporter
QF06_RS03480	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
QF06_RS03485	COG1278	Cold shock
QF06_RS03490	COG1464	Belongs to the NlpA lipoprotein family
QF06_RS03495	COG3706	GGDEF domain
QF06_RS03500	COG1823	symporter activity
QF06_RS03530	COG5577	PFAM Coat F domain
QF06_RS03535	COG4085	toxin activity
QF06_RS03535	COG1525	nuclease
QF06_RS03535	COG0737	Belongs to the 5'-nucleotidase family
QF06_RS03540	COG3764	Sortase (surface protein transpeptidase)
QF06_RS03545	COG0564	pseudouridine synthase activity
QF06_RS03555	COG0517	IMP dehydrogenase activity
QF06_RS03560	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
QF06_RS03565	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
QF06_RS03565	COG3153	acetyltransferase
QF06_RS03570	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
QF06_RS03575	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
QF06_RS03580	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
QF06_RS03585	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
QF06_RS03590	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
QF06_RS03595	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
QF06_RS03600	COG2203	Gaf domain
QF06_RS03600	COG4585	Histidine kinase
QF06_RS03605	COG2197	response regulator
QF06_RS03610	COG0431	NADPH-dependent FMN reductase
QF06_RS03625	COG1388	LysM domain
QF06_RS03625	COG0791	NLP P60 protein
QF06_RS03630	COG1959	2 iron, 2 sulfur cluster binding
QF06_RS03635	COG0668	transmembrane transport
QF06_RS03640	COG2719	SpoVR family
QF06_RS03645	COG1785	Belongs to the alkaline phosphatase family
QF06_RS03650	COG0791	NLP P60 protein
QF06_RS03650	COG1388	LysM domain
QF06_RS03655	COG0583	DNA-binding transcription factor activity
QF06_RS03660	COG0372	Belongs to the citrate synthase family
QF06_RS03665	COG1028	Short-chain dehydrogenase reductase Sdr
QF06_RS03670	COG0531	amino acid
QF06_RS03675	COG0733	neurotransmitter:sodium symporter activity
QF06_RS03680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
QF06_RS03685	COG0456	acetyltransferase
QF06_RS03700	COG1595	DNA-templated transcription, initiation
QF06_RS03705	COG0667	Aldo Keto reductase
QF06_RS03710	COG0204	Acyl-transferase
QF06_RS03715	COG1253	flavin adenine dinucleotide binding
QF06_RS03720	COG0789	Transcriptional regulator
QF06_RS03725	COG0436	Aminotransferase
QF06_RS03730	COG1253	flavin adenine dinucleotide binding
QF06_RS03735	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
QF06_RS03740	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
QF06_RS03745	COG0584	glycerophosphoryl diester phosphodiesterase
QF06_RS03750	COG0668	transmembrane transport
QF06_RS03755	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
QF06_RS03760	COG0726	polysaccharide deacetylase
QF06_RS03765	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
QF06_RS03770	COG1757	Na H antiporter
QF06_RS03775	COG0589	response to stress
QF06_RS03780	COG1132	(ABC) transporter
QF06_RS03785	COG1132	(ABC) transporter
QF06_RS03790	COG0702	epimerase
QF06_RS03805	COG0189	ligase activity
QF06_RS03810	COG0189	ligase activity
QF06_RS03815	COG4399	Belongs to the UPF0754 family
QF06_RS03820	COG3679	Belongs to the UPF0342 family
QF06_RS03825	COG4335	DNA alkylation repair
QF06_RS03830	COG0561	phosphatase activity
QF06_RS03835	COG0635	Involved in the biosynthesis of porphyrin-containing compound
QF06_RS03840	COG0475	glutathione-regulated potassium exporter activity
QF06_RS03845	COG0490	domain, Protein
QF06_RS03855	COG1024	Enoyl-CoA hydratase
QF06_RS03865	COG4152	abc transporter atp-binding protein
QF06_RS03870	COG1668	transmembrane transport
QF06_RS03875	COG0420	3'-5' exonuclease activity
QF06_RS03880	COG4717	serine-type aminopeptidase activity
QF06_RS03885	COG3481	metal-dependent phosphohydrolase, HD sub domain
QF06_RS03895	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
QF06_RS03920	COG1846	Transcriptional regulator
QF06_RS03925	COG4980	gas vesicle protein
QF06_RS03940	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
QF06_RS03945	COG0537	adenosine 5'-monophosphoramidase activity
QF06_RS03950	COG1131	(ABC) transporter
QF06_RS03955	COG4473	ABC transporter
QF06_RS03965	COG1473	amidohydrolase
QF06_RS03970	COG3069	C4-dicarboxylate transmembrane transporter activity
QF06_RS03980	COG2329	Antibiotic biosynthesis monooxygenase
QF06_RS03985	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
QF06_RS03990	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
QF06_RS03995	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
QF06_RS04000	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
QF06_RS04005	COG1309	transcriptional regulator
QF06_RS04010	COG1511	domain protein
QF06_RS04015	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
QF06_RS04020	COG4377	Putative membrane peptidase family (DUF2324)
QF06_RS04030	COG1363	Peptidase, m42
QF06_RS04035	COG4405	Protein conserved in bacteria
QF06_RS04040	COG1301	dicarboxylic acid transport
QF06_RS04045	COG1234	tRNA 3'-trailer cleavage
QF06_RS04050	COG0095	Lipoate-protein ligase
QF06_RS04055	COG0702	epimerase
QF06_RS04060	COG0318	PFAM AMP-dependent synthetase and ligase
QF06_RS04070	COG0501	Belongs to the peptidase M48B family
QF06_RS04080	COG0456	acetyltransferase
QF06_RS04085	COG0604	alcohol dehydrogenase
QF06_RS04090	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
QF06_RS04095	COG0406	alpha-ribazole phosphatase activity
QF06_RS04100	COG0183	Belongs to the thiolase family
QF06_RS04105	COG0318	PFAM AMP-dependent synthetase and ligase
QF06_RS04110	COG1268	BioY protein
QF06_RS04115	COG0840	transmembrane signaling receptor activity
QF06_RS04120	COG0723	plastoquinol--plastocyanin reductase activity
QF06_RS04120	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
QF06_RS04125	COG1028	Short-chain dehydrogenase reductase Sdr
QF06_RS04135	COG4903	ComK protein
QF06_RS04140	COG1028	Short-chain dehydrogenase reductase Sdr
QF06_RS04150	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
QF06_RS04165	COG0398	Pfam SNARE associated Golgi protein
QF06_RS04170	COG0681	Belongs to the peptidase S26 family
QF06_RS04175	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
QF06_RS04180	COG1846	Transcriptional regulator
QF06_RS04195	COG0738	Major facilitator superfamily
QF06_RS04200	COG0673	inositol 2-dehydrogenase activity
QF06_RS04205	COG0561	phosphatase activity
QF06_RS04210	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
QF06_RS04215	COG1609	Transcriptional regulator
QF06_RS04220	COG3180	Ammonia monooxygenase
QF06_RS04225	COG0477	Major facilitator Superfamily
QF06_RS04225	COG2814	Major facilitator Superfamily
QF06_RS04230	COG4533	DNA binding
QF06_RS04240	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
QF06_RS04245	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
QF06_RS04250	COG1074	ATP-dependent DNA helicase activity
QF06_RS04255	COG0420	3'-5' exonuclease activity
QF06_RS04260	COG0419	ATPase involved in DNA repair
QF06_RS04265	COG1403	HNH endonuclease
QF06_RS04305	COG5337	Spore coat protein CotH
QF06_RS04310	COG0179	Fumarylacetoacetate (FAA) hydrolase
QF06_RS04320	COG1404	Belongs to the peptidase S8 family
QF06_RS04330	COG0367	asparagine synthase
QF06_RS04335	COG2318	DinB family
QF06_RS04340	COG1562	ergosterol biosynthetic process
QF06_RS04345	COG0534	Mate efflux family protein
QF06_RS04350	COG1917	Cupin 2, conserved barrel domain protein
QF06_RS04350	COG2207	Transcriptional regulator
QF06_RS04355	COG1609	Transcriptional regulator
QF06_RS04360	COG0673	inositol 2-dehydrogenase activity
QF06_RS04365	COG2318	DinB family
QF06_RS04370	COG1279	arginine transmembrane transporter activity
QF06_RS04375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
QF06_RS04380	COG1357	PFAM Pentapeptide repeats (8 copies)
QF06_RS04385	COG2267	carboxylic ester hydrolase activity
QF06_RS04390	COG0529	Catalyzes the synthesis of activated sulfate
QF06_RS04395	COG2046	Belongs to the sulfate adenylyltransferase family
QF06_RS04400	COG0175	sulfate reduction
QF06_RS04405	COG2045	Belongs to the ComB family
QF06_RS04410	COG1809	phosphosulfolactate synthase activity
QF06_RS04415	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
QF06_RS04420	COG4948	Mandelate Racemase Muconate Lactonizing
QF06_RS04425	COG2814	Major facilitator Superfamily
QF06_RS04430	COG0454	-acetyltransferase
QF06_RS04435	COG2153	protein acetylation
QF06_RS04440	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
QF06_RS04440	COG0646	methionine synthase
QF06_RS04445	COG1666	GTP binding
QF06_RS04450	COG2996	Protein conserved in bacteria
QF06_RS04470	COG1695	Transcriptional regulator
QF06_RS04485	COG3227	Zinc metalloprotease (Elastase)
QF06_RS04490	COG1307	EDD domain protein, DegV family
QF06_RS04495	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
QF06_RS04510	COG0561	phosphatase activity
QF06_RS04515	COG1073	alpha beta
QF06_RS04520	COG2151	metal-sulfur cluster biosynthetic enzyme
QF06_RS04525	COG0277	FAD linked oxidase domain protein
QF06_RS04530	COG2271	Major facilitator Superfamily
QF06_RS04535	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
QF06_RS04540	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
QF06_RS04550	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
QF06_RS04555	COG0505	Belongs to the CarA family
QF06_RS04560	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
QF06_RS04565	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
QF06_RS04580	COG2267	carboxylic ester hydrolase activity
QF06_RS04590	COG1744	ABC transporter substrate-binding protein PnrA-like
QF06_RS04605	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
QF06_RS04610	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
QF06_RS04615	COG5504	Zn-dependent protease
QF06_RS04620	COG0444	Belongs to the ABC transporter superfamily
QF06_RS04625	COG4608	Belongs to the ABC transporter superfamily
QF06_RS04635	COG0601	transmembrane transport
QF06_RS04640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
QF06_RS04650	COG0180	Tryptophanyl-tRNA synthetase
QF06_RS04655	COG4166	transmembrane transport
QF06_RS04660	COG0601	transmembrane transport
QF06_RS04665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
QF06_RS04670	COG0444	Belongs to the ABC transporter superfamily
QF06_RS04675	COG4608	Belongs to the ABC transporter superfamily
QF06_RS04680	COG2814	Major facilitator Superfamily
QF06_RS04685	COG0456	acetyltransferase
QF06_RS04690	COG1393	Belongs to the ArsC family
QF06_RS04695	COG0861	Integral membrane protein TerC family
QF06_RS04700	COG4862	establishment of competence for transformation
QF06_RS04705	COG4469	Competence protein
QF06_RS04710	COG1164	Oligoendopeptidase f
QF06_RS04725	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
QF06_RS04730	COG2346	COG2346, Truncated hemoglobins
QF06_RS04735	COG0741	lytic transglycosylase activity
QF06_RS04740	COG4116	CYTH
QF06_RS04750	COG2357	RelA SpoT domain protein
QF06_RS04755	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
QF06_RS04760	COG0564	pseudouridine synthase activity
QF06_RS04765	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
QF06_RS04770	COG0475	glutathione-regulated potassium exporter activity
QF06_RS04770	COG0569	domain protein
QF06_RS04775	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
QF06_RS04780	COG0352	thiamine-phosphate diphosphorylase activity
QF06_RS04785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
QF06_RS04790	COG2104	thiamine diphosphate biosynthetic process
QF06_RS04795	COG2022	thiamine diphosphate biosynthetic process
QF06_RS04800	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
QF06_RS04805	COG0351	phosphomethylpyrimidine kinase
QF06_RS04810	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
QF06_RS04865	COG0210	DNA helicase
QF06_RS04875	COG2153	protein acetylation
QF06_RS04880	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
QF06_RS04885	COG2382	esterase
QF06_RS04890	COG0626	cystathionine gamma-synthase activity
QF06_RS04895	COG0626	cystathionine gamma-synthase activity
QF06_RS04900	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
QF06_RS04905	COG5505	Protein of unknown function (DUF819)
QF06_RS04940	COG5444	nuclease activity
QF06_RS04960	COG0457	Tetratricopeptide repeat
QF06_RS04965	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
QF06_RS04970	COG1028	Short-chain dehydrogenase reductase Sdr
QF06_RS04980	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
QF06_RS04980	COG3711	transcriptional antiterminator
QF06_RS04985	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
QF06_RS04985	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
QF06_RS04985	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
QF06_RS04990	COG1482	cell wall glycoprotein biosynthetic process
QF06_RS05000	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
QF06_RS05010	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
QF06_RS05025	COG0109	protoheme IX farnesyltransferase activity
QF06_RS05035	COG0726	polysaccharide deacetylase
QF06_RS05050	COG2205	protein histidine kinase activity
QF06_RS05060	COG3383	formate dehydrogenase (NAD+) activity
QF06_RS05065	COG2427	Protein of unknown function (DUF1641)
QF06_RS05085	COG2124	cytochrome p450
QF06_RS05090	COG1819	glycosyl
QF06_RS05110	COG1587	Uroporphyrinogen-III synthase
QF06_RS05115	COG0390	transport system, permease component
QF06_RS05120	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
QF06_RS05125	COG0697	spore germination
QF06_RS05130	COG4297	protein containing double-stranded beta helix domain
QF06_RS05145	COG1904	glucuronate isomerase
QF06_RS05150	COG2211	Major facilitator Superfamily
QF06_RS05155	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
QF06_RS05160	COG1063	alcohol dehydrogenase
QF06_RS05165	COG1312	Catalyzes the dehydration of D-mannonate
QF06_RS05170	COG1028	Short-chain dehydrogenase reductase Sdr
QF06_RS05175	COG2271	Major facilitator Superfamily
QF06_RS05180	COG1609	Transcriptional regulator
QF06_RS05185	COG0246	Mannitol dehydrogenase
QF06_RS05190	COG2721	sulfolactate sulfo-lyase activity
QF06_RS05195	COG0730	response to heat
QF06_RS05200	COG2318	DinB family
QF06_RS05205	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
QF06_RS05210	COG0457	Tetratricopeptide repeat
QF06_RS05220	COG2350	Protein conserved in bacteria
QF06_RS05225	COG3409	Peptidoglycan-binding domain 1 protein
QF06_RS05225	COG5632	N-Acetylmuramoyl-L-alanine amidase
QF06_RS05225	COG1388	LysM domain
QF06_RS05235	COG4195	phage-related replication protein
QF06_RS05240	COG3546	catalase activity
QF06_RS05245	COG2856	Zn peptidase
QF06_RS05250	COG1396	sequence-specific DNA binding
QF06_RS05260	COG1522	sequence-specific DNA binding
QF06_RS05265	COG1484	DNA-dependent DNA replication
QF06_RS05280	COG1595	DNA-templated transcription, initiation
QF06_RS05285	COG5484	DNA packaging
QF06_RS05285	COG3728	DNA packaging
QF06_RS05290	COG1783	phage Terminase large subunit
QF06_RS05295	COG5518	Phage portal protein
QF06_RS05300	COG0338	D12 class N6 adenine-specific DNA methyltransferase
QF06_RS05305	COG4653	Phage capsid family
QF06_RS05350	COG5412	phage tail tape measure protein
QF06_RS05350	COG3953	SLT domain
QF06_RS05355	COG1652	LysM domain
QF06_RS05360	COG4193	domain, Protein
QF06_RS05370	COG3628	GPW Gp25 family protein
QF06_RS05375	COG3299	homolog of phage Mu protein gp47
QF06_RS05380	COG3778	Protein conserved in bacteria
QF06_RS05420	COG5632	N-Acetylmuramoyl-L-alanine amidase
QF06_RS05420	COG3409	Peptidoglycan-binding domain 1 protein
QF06_RS05435	COG0306	phosphate transporter
QF06_RS05440	COG1392	Phosphate transport regulator
QF06_RS05445	COG0531	amino acid
QF06_RS05450	COG0346	lactoylglutathione lyase activity
QF06_RS05455	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
QF06_RS05460	COG0463	Glycosyl transferase, family 2
QF06_RS05465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
QF06_RS05470	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
QF06_RS05475	COG2362	D-Aminopeptidase
QF06_RS05480	COG0601	transmembrane transport
QF06_RS05485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
QF06_RS05490	COG0444	Belongs to the ABC transporter superfamily
QF06_RS05495	COG4166	transmembrane transport
QF06_RS05500	COG1619	proteins homologs of microcin C7 resistance protein MccF
QF06_RS05505	COG4948	Mandelate Racemase Muconate Lactonizing
QF06_RS05510	COG0791	NLP P60 protein
QF06_RS05515	COG4608	Belongs to the ABC transporter superfamily
QF06_RS05520	COG2706	6-phosphogluconolactonase activity
QF06_RS05525	COG1834	amidinotransferase
QF06_RS05530	COG1607	acyl-coa hydrolase
QF06_RS05535	COG1017	nitric oxide dioxygenase activity
QF06_RS05535	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
QF06_RS05545	COG2323	membrane
QF06_RS05550	COG2318	DinB family
QF06_RS05555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
QF06_RS05560	COG2076	Multidrug Resistance protein
QF06_RS05565	COG2076	Multidrug Resistance protein
QF06_RS05570	COG0788	formyltetrahydrofolate deformylase activity
QF06_RS05575	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
QF06_RS05580	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
QF06_RS05585	COG1764	response to oxidative stress
QF06_RS05590	COG1846	Transcriptional regulator
QF06_RS05595	COG1764	response to oxidative stress
QF06_RS05605	COG0590	tRNA wobble adenosine to inosine editing
QF06_RS05610	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
QF06_RS05615	COG1404	Belongs to the peptidase S8 family
QF06_RS05620	COG1366	Belongs to the anti-sigma-factor antagonist family
QF06_RS05625	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
QF06_RS05630	COG1122	ATPase activity
QF06_RS05635	COG4721	ABC-type cobalt transport system, permease component
QF06_RS05645	COG0745	RESPONSE REGULATOR receiver
QF06_RS05650	COG3850	Histidine kinase
QF06_RS05650	COG5002	protein histidine kinase activity
QF06_RS05655	COG3212	peptidase
QF06_RS05660	COG3212	peptidase
QF06_RS05670	COG2239	Acts as a magnesium transporter
QF06_RS05675	COG0789	Transcriptional regulator
QF06_RS05685	COG1846	Transcriptional regulator
QF06_RS05690	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
QF06_RS05695	COG0726	polysaccharide deacetylase
QF06_RS05700	COG1408	metallophosphoesterase
QF06_RS05710	COG0463	Glycosyl transferase, family 2
QF06_RS05715	COG3285	dna ligase
QF06_RS05715	COG1793	dna ligase
QF06_RS05720	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
QF06_RS05725	COG3300	MHYT domain
QF06_RS05725	COG5001	Diguanylate cyclase
QF06_RS05730	COG0586	Pfam SNARE associated Golgi protein
QF06_RS05735	COG0861	Integral membrane protein TerC family
QF06_RS05740	COG1191	sigma factor activity
QF06_RS05760	COG0501	Belongs to the peptidase M48B family
QF06_RS05765	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
QF06_RS05770	COG3594	Acyltransferase
QF06_RS05775	COG5002	protein histidine kinase activity
QF06_RS05780	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
QF06_RS05785	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
QF06_RS05790	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
QF06_RS05795	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
QF06_RS05800	COG0436	Aminotransferase
QF06_RS05805	COG1850	ribulose-bisphosphate carboxylase activity
QF06_RS05810	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
QF06_RS05815	COG0235	Class ii aldolase
QF06_RS05820	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
QF06_RS05825	COG3339	Conserved Protein
QF06_RS05840	COG3852	Histidine kinase
QF06_RS05845	COG1846	Transcriptional regulator
QF06_RS05850	COG1360	Flagellar Motor Protein
QF06_RS05855	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
QF06_RS05860	COG0542	response to heat
QF06_RS05865	COG3949	Membrane
QF06_RS05870	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
QF06_RS05875	COG0720	synthase
QF06_RS05880	COG0602	queuosine metabolic process
QF06_RS05885	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
QF06_RS05890	COG1733	regulation of RNA biosynthetic process
QF06_RS05895	COG1028	Short-chain dehydrogenase reductase Sdr
QF06_RS05900	COG4641	Protein conserved in bacteria
QF06_RS05900	COG1388	LysM domain
QF06_RS05905	COG1388	LysM domain
QF06_RS05910	COG3858	chitin binding
QF06_RS05915	COG3858	chitin binding
QF06_RS05925	COG4873	Protein conserved in bacteria
QF06_RS05935	COG3773	Cell wall hydrolase
QF06_RS05940	COG2244	polysaccharide biosynthetic process
QF06_RS05945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
QF06_RS05950	COG2217	Heavy metal translocating P-type atpase
QF06_RS05960	COG0006	proline dipeptidase activity
QF06_RS05965	COG1609	Transcriptional regulator
QF06_RS05970	COG3711	transcriptional antiterminator
QF06_RS05975	COG2190	(PTS) system
QF06_RS05975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
QF06_RS05975	COG1263	PTS System
QF06_RS05980	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
QF06_RS05985	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
QF06_RS05995	COG1533	DNA photolyase activity
QF06_RS06000	COG0456	acetyltransferase
QF06_RS06005	COG0840	transmembrane signaling receptor activity
QF06_RS06010	COG2084	Dehydrogenase
QF06_RS06015	COG4257	antibiotic catabolic process
QF06_RS06020	COG2340	Cysteine-rich secretory protein family
QF06_RS06025	COG0768	penicillin binding
QF06_RS06030	COG4191	Histidine kinase
QF06_RS06035	COG0436	Aminotransferase
QF06_RS06040	COG0784	Response regulator, receiver
QF06_RS06040	COG0835	chemotaxis
QF06_RS06050	COG2814	Major facilitator Superfamily
QF06_RS06055	COG1376	ErfK ybiS ycfS ynhG family protein
QF06_RS06060	COG1408	metallophosphoesterase
QF06_RS06065	COG1028	Short-chain dehydrogenase reductase Sdr
QF06_RS06070	COG2200	EAL domain
QF06_RS06075	COG4703	Protein of unknown function (DUF1797)
QF06_RS06080	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
QF06_RS06090	COG0517	IMP dehydrogenase activity
QF06_RS06095	COG0583	DNA-binding transcription factor activity
QF06_RS06100	COG0716	FMN binding
QF06_RS06110	COG0716	FMN binding
QF06_RS06115	COG2171	N-acyltransferase activity
QF06_RS06120	COG1473	amidohydrolase
QF06_RS06130	COG0668	transmembrane transport
QF06_RS06135	COG0450	alkyl hydroperoxide reductase
QF06_RS06140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
QF06_RS06155	COG0746	molybdenum cofactor guanylyltransferase activity
QF06_RS06160	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
QF06_RS06165	COG0303	'Molybdopterin
QF06_RS06170	COG1763	Mo-molybdopterin cofactor biosynthetic process
QF06_RS06175	COG0314	molybdopterin synthase activity
QF06_RS06180	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
QF06_RS06185	COG1132	(ABC) transporter
QF06_RS06190	COG1132	(ABC) transporter
QF06_RS06200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
QF06_RS06205	COG1136	(ABC) transporter
QF06_RS06210	COG0577	efflux transmembrane transporter activity
QF06_RS06215	COG1349	DNA-binding transcription factor activity
QF06_RS06220	COG1105	Belongs to the carbohydrate kinase PfkB family
QF06_RS06225	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
QF06_RS06225	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
QF06_RS06225	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
QF06_RS06230	COG0681	Belongs to the peptidase S26 family
QF06_RS06240	COG0488	(ABC) transporter
QF06_RS06245	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
QF06_RS06250	COG2309	aminopeptidase activity
QF06_RS06255	COG1077	Cell shape determining protein MreB Mrl
QF06_RS06260	COG2002	toxin-antitoxin pair type II binding
QF06_RS06265	COG3852	Histidine kinase
QF06_RS06270	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
QF06_RS06270	COG2105	PFAM AIG2 family protein
QF06_RS06275	COG0569	domain protein
QF06_RS06280	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
QF06_RS06285	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
QF06_RS06290	COG5503	Protein of unknown function (DUF1447)
QF06_RS06295	COG0561	phosphatase activity
QF06_RS06300	COG0242	peptide deformylase activity
QF06_RS06310	COG0497	DNA recombination
QF06_RS06315	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
QF06_RS06320	COG0022	dehydrogenase e1 component
QF06_RS06325	COG0508	dehydrogenase complex catalyzes the overall conversion of
QF06_RS06330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
QF06_RS06335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
QF06_RS06340	COG1982	Orn Lys Arg decarboxylase major
QF06_RS06345	COG4476	Belongs to the UPF0223 family
QF06_RS06350	COG4493	Belongs to the UPF0637 family
QF06_RS06360	COG0483	inositol monophosphate 1-phosphatase activity
QF06_RS06370	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
QF06_RS06410	COG1217	gtp-binding protein TYPA
QF06_RS06420	COG4896	Protein conserved in bacteria
QF06_RS06430	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
QF06_RS06435	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
QF06_RS06440	COG2066	Belongs to the glutaminase family
QF06_RS06445	COG4838	Belongs to the UPF0358 family
QF06_RS06450	COG0772	Belongs to the SEDS family
QF06_RS06455	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
QF06_RS06460	COG1612	heme a metabolic process
QF06_RS06465	COG0109	protoheme IX farnesyltransferase activity
QF06_RS06470	COG2010	Cytochrome c
QF06_RS06470	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
QF06_RS06475	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
QF06_RS06480	COG1845	cytochrome c oxidase, subunit III
QF06_RS06485	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
QF06_RS06490	COG3336	cytochrome c oxidase
QF06_RS06500	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
QF06_RS06505	COG2340	Cysteine-rich secretory protein family
QF06_RS06520	COG3679	Belongs to the UPF0342 family
QF06_RS06525	COG4471	UPF0298 protein
QF06_RS06530	COG0742	ribosomal rna small subunit methyltransferase
QF06_RS06535	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
QF06_RS06540	COG3314	Sporulation integral membrane protein YlbJ
QF06_RS06545	COG1752	Esterase of the alpha-beta hydrolase superfamily
QF06_RS06550	COG3480	Lon protease (S16) C-terminal proteolytic domain
QF06_RS06555	COG1323	Belongs to the UPF0348 family
QF06_RS06565	COG1399	metal-binding, possibly nucleic acid-binding protein
QF06_RS06575	COG0454	-acetyltransferase
QF06_RS06580	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
QF06_RS06585	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
QF06_RS06590	COG2001	Belongs to the MraZ family
QF06_RS06595	COG0275	rRNA processing
QF06_RS06600	COG4839	cell division protein FtsL
QF06_RS06605	COG0768	penicillin binding
QF06_RS06610	COG0768	penicillin binding
QF06_RS06615	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
QF06_RS06620	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
QF06_RS06625	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
QF06_RS06630	COG0772	Belongs to the SEDS family
QF06_RS06635	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
QF06_RS06640	COG0812	UDP-N-acetylmuramate dehydrogenase activity
QF06_RS06645	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
QF06_RS06650	COG3879	Bacterial protein of unknown function (DUF881)
QF06_RS06655	COG3879	Bacterial protein of unknown function (DUF881)
QF06_RS06660	COG3856	small basic protein
QF06_RS06665	COG0849	cell division
QF06_RS06670	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
QF06_RS06675	COG1404	Belongs to the peptidase S8 family
QF06_RS06675	COG4412	M6 family metalloprotease domain protein
QF06_RS06685	COG1191	sigma factor activity
QF06_RS06690	COG1191	sigma factor activity
QF06_RS06695	COG1119	ATPase activity
QF06_RS06700	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
QF06_RS06705	COG1873	PFAM PRC-barrel domain
QF06_RS06710	COG1496	oxidoreductase activity
QF06_RS06715	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
QF06_RS06720	COG1799	cell septum assembly
QF06_RS06725	COG0762	integral membrane protein
QF06_RS06730	COG2302	S4 RNA-binding domain
QF06_RS06735	COG3599	regulation of cell shape
QF06_RS06740	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
QF06_RS06745	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
QF06_RS06750	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
QF06_RS06755	COG0564	pseudouridine synthase activity
QF06_RS06760	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
QF06_RS06765	COG2233	PERMEase
QF06_RS06770	COG0540	Belongs to the ATCase OTCase family
QF06_RS06775	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
QF06_RS06780	COG0505	Belongs to the CarA family
QF06_RS06785	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
QF06_RS06790	COG0543	2 iron, 2 sulfur cluster binding
QF06_RS06795	COG0167	dihydroorotate dehydrogenase activity
QF06_RS06800	COG0284	orotidine-5'-phosphate decarboxylase activity
QF06_RS06805	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
QF06_RS06810	COG0175	sulfate reduction
QF06_RS06815	COG0306	phosphate transporter
QF06_RS06820	COG2046	Belongs to the sulfate adenylyltransferase family
QF06_RS06825	COG0529	Catalyzes the synthesis of activated sulfate
QF06_RS06830	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
QF06_RS06835	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
QF06_RS06840	COG1648	precorrin-2 dehydrogenase activity
QF06_RS06845	COG1293	RNA-binding protein homologous to eukaryotic snRNP
QF06_RS06850	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
QF06_RS06855	COG1561	YicC-like family, N-terminal region
QF06_RS06865	COG0194	GDP metabolic process
QF06_RS06870	COG1758	RNA polymerase activity
QF06_RS06875	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
QF06_RS06880	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
QF06_RS06885	COG0242	peptide deformylase activity
QF06_RS06890	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
QF06_RS06895	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
QF06_RS06895	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
QF06_RS06900	COG0820	rRNA (adenine-C2-)-methyltransferase activity
QF06_RS06905	COG0631	protein serine/threonine phosphatase activity
QF06_RS06910	COG2815	serine threonine protein kinase
QF06_RS06910	COG0515	serine threonine protein kinase
QF06_RS06915	COG1162	GTPase activity
QF06_RS06920	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
QF06_RS06925	COG1564	THIamine pyrophosphokinase
QF06_RS06935	COG0227	Belongs to the bacterial ribosomal protein bL28 family
QF06_RS06940	COG1302	Protein conserved in bacteria
QF06_RS06945	COG1461	Dihydroxyacetone kinase
QF06_RS06950	COG1760	l-serine dehydratase
QF06_RS06955	COG1760	l-serine dehydratase
QF06_RS06960	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
QF06_RS06965	COG2050	protein possibly involved in aromatic compounds catabolism
QF06_RS06965	COG1349	DNA-binding transcription factor activity
QF06_RS06970	COG0416	fatty acid biosynthetic process
QF06_RS06975	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
QF06_RS06980	COG1028	Short-chain dehydrogenase reductase Sdr
QF06_RS06990	COG0571	ribonuclease III activity
QF06_RS06995	COG1196	nuclear chromosome segregation
QF06_RS07000	COG0552	protein localization to endoplasmic reticulum
QF06_RS07010	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
QF06_RS07015	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
QF06_RS07020	COG0228	four-way junction DNA binding
QF06_RS07025	COG1837	Belongs to the UPF0109 family
QF06_RS07035	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
QF06_RS07040	COG0336	Belongs to the RNA methyltransferase TrmD family
QF06_RS07045	COG0335	large ribosomal subunit rRNA binding
QF06_RS07050	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
QF06_RS07055	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
QF06_RS07065	COG2257	FlhB HrpN YscU SpaS Family
QF06_RS07070	COG0045	succinate-CoA ligase (ADP-forming) activity
QF06_RS07075	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
QF06_RS07080	COG0758	DNA mediated transformation
QF06_RS07085	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
QF06_RS07090	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
QF06_RS07095	COG4974	Belongs to the 'phage' integrase family
QF06_RS07100	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
QF06_RS07105	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
QF06_RS07110	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
QF06_RS07115	COG1815	bacterial-type flagellum-dependent cell motility
QF06_RS07120	COG1558	bacterial-type flagellum-dependent cell motility
QF06_RS07125	COG1677	Flagellar hook-basal body complex protein FliE
QF06_RS07130	COG1766	The M ring may be actively involved in energy transduction
QF06_RS07135	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
QF06_RS07140	COG1317	bacterial-type flagellum organization
QF06_RS07145	COG1157	protein secretion by the type III secretion system
QF06_RS07150	COG2882	bacterial-type flagellum organization
QF06_RS07155	COG3334	PFAM MgtE intracellular
QF06_RS07160	COG3144	bacterial-type flagellum assembly
QF06_RS07165	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
QF06_RS07170	COG4786	Flagellar basal body rod
QF06_RS07175	COG1582	Flagellar protein (FlbD)
QF06_RS07180	COG1580	Controls the rotational direction of flagella during chemotaxis
QF06_RS07185	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
QF06_RS07190	COG1776	CheC inhibitor of MCP methylation
QF06_RS07190	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
QF06_RS07195	COG2201	protein-glutamate methylesterase activity
QF06_RS07200	COG3190	flagellar
QF06_RS07205	COG1338	Plays a role in the flagellum-specific transport system
QF06_RS07210	COG1987	bacterial-type flagellum assembly
QF06_RS07215	COG1684	flagellar biosynthetic protein fliR
QF06_RS07220	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
QF06_RS07225	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
QF06_RS07230	COG1419	protein localization to endoplasmic reticulum
QF06_RS07235	COG0455	bacterial-type flagellum organization
QF06_RS07240	COG2201	protein-glutamate methylesterase activity
QF06_RS07245	COG0643	Histidine kinase
QF06_RS07245	COG2198	Histidine kinase
QF06_RS07250	COG0835	chemotaxis
QF06_RS07255	COG1776	CheC inhibitor of MCP methylation
QF06_RS07260	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
QF06_RS07265	COG1191	sigma factor activity
QF06_RS07275	COG0052	Belongs to the universal ribosomal protein uS2 family
QF06_RS07280	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
QF06_RS07285	COG0528	UMP kinase activity
QF06_RS07290	COG0233	cytoplasmic translational termination
QF06_RS07295	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
QF06_RS07300	COG4589	Belongs to the CDS family
QF06_RS07305	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
QF06_RS07310	COG0750	zinc metalloprotease
QF06_RS07315	COG0442	prolyl-tRNA aminoacylation
QF06_RS07320	COG2176	DNA-directed DNA polymerase activity
QF06_RS07345	COG0779	Required for maturation of 30S ribosomal subunits
QF06_RS07350	COG0195	Participates in both transcription termination and antitermination
QF06_RS07355	COG2740	Nucleic-acid-binding protein implicated in transcription termination
QF06_RS07360	COG1358	cellular component organization or biogenesis
QF06_RS07365	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
QF06_RS07370	COG1550	Protein conserved in bacteria
QF06_RS07375	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
QF06_RS07380	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
QF06_RS07385	COG0196	riboflavin kinase activity
QF06_RS07390	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
QF06_RS07395	COG1185	polyribonucleotide nucleotidyltransferase activity
QF06_RS07400	COG0726	polysaccharide deacetylase
QF06_RS07405	COG0612	Peptidase, M16
QF06_RS07410	COG1873	PFAM PRC-barrel domain
QF06_RS07415	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
QF06_RS07420	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
QF06_RS07425	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
QF06_RS07430	COG0527	aspartate kinase activity
QF06_RS07435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
QF06_RS07440	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
QF06_RS07445	COG0740	serine-type endopeptidase activity
QF06_RS07455	COG1674	ftsk spoiiie
QF06_RS07455	COG4980	gas vesicle protein
QF06_RS07460	COG2188	Transcriptional regulator
QF06_RS07465	COG2814	Major facilitator Superfamily
QF06_RS07470	COG0612	Peptidase, M16
QF06_RS07475	COG0612	Peptidase, M16
QF06_RS07480	COG0300	oxidoreductase activity
QF06_RS07495	COG1426	Protein conserved in bacteria
QF06_RS07500	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
QF06_RS07505	COG1058	Belongs to the CinA family
QF06_RS07505	COG1546	Belongs to the CinA family
QF06_RS07510	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
QF06_RS07515	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
QF06_RS07520	COG1418	mRNA catabolic process
QF06_RS07525	COG1692	metallophosphoesterase
QF06_RS07530	COG2359	stage V sporulation protein S
QF06_RS07535	COG1063	alcohol dehydrogenase
QF06_RS07540	COG0156	8-amino-7-oxononanoate synthase activity
QF06_RS07545	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
QF06_RS07550	COG4550	Control of competence regulator ComK, YlbF/YmcA
QF06_RS07560	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
QF06_RS07565	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
QF06_RS07580	COG3226	Transcriptional regulator
QF06_RS07585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
QF06_RS07595	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
QF06_RS07600	COG3321	synthase
QF06_RS07605	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
QF06_RS07605	COG2070	2-Nitropropane dioxygenase
QF06_RS07610	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
QF06_RS07615	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
QF06_RS07620	COG3425	synthase
QF06_RS07625	COG1024	Enoyl-CoA hydratase
QF06_RS07630	COG1024	Enoyl-CoA hydratase
QF06_RS07635	COG1028	Short-chain dehydrogenase reductase Sdr
QF06_RS07635	COG0300	oxidoreductase activity
QF06_RS07635	COG0318	PFAM AMP-dependent synthetase and ligase
QF06_RS07635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
QF06_RS07635	COG3321	synthase
QF06_RS07640	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
QF06_RS07640	COG0300	oxidoreductase activity
QF06_RS07640	COG4221	oxidoreductase activity
QF06_RS07640	COG3321	synthase
QF06_RS07645	COG1028	Short-chain dehydrogenase reductase Sdr
QF06_RS07645	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
QF06_RS07645	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
QF06_RS07645	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
QF06_RS07645	COG3321	synthase
QF06_RS07650	COG1028	Short-chain dehydrogenase reductase Sdr
QF06_RS07650	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
QF06_RS07650	COG3321	synthase
QF06_RS07650	COG4221	oxidoreductase activity
QF06_RS07655	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
QF06_RS07655	COG3321	synthase
QF06_RS07655	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
QF06_RS07655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
QF06_RS07660	COG2124	cytochrome p450
QF06_RS07670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
QF06_RS07675	COG1404	Belongs to the peptidase S8 family
QF06_RS07685	COG4195	phage-related replication protein
QF06_RS07690	COG1764	response to oxidative stress
QF06_RS07695	COG2076	Multidrug Resistance protein
QF06_RS07700	COG2076	Multidrug Resistance protein
QF06_RS07715	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
QF06_RS07720	COG1923	regulation of RNA biosynthetic process
QF06_RS07735	COG1780	Probably involved in ribonucleotide reductase function
QF06_RS07740	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
QF06_RS07745	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
QF06_RS07750	COG4112	unkown
QF06_RS07755	COG0860	N-Acetylmuramoyl-L-alanine amidase
QF06_RS07760	COG0464	growth
QF06_RS07765	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
QF06_RS07770	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
QF06_RS07775	COG0789	Transcriptional regulator
QF06_RS07780	COG0174	glutamine synthetase
QF06_RS07805	COG4282	regulation of fungal-type cell wall biogenesis
QF06_RS07810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
QF06_RS07830	COG0135	phosphoribosylanthranilate isomerase activity
QF06_RS07835	COG2211	Major facilitator Superfamily
QF06_RS07840	COG3507	Belongs to the glycosyl hydrolase 43 family
QF06_RS07845	COG1940	carbohydrate kinase activity
QF06_RS07850	COG2115	Belongs to the xylose isomerase family
QF06_RS07855	COG1070	Carbohydrate kinase
QF06_RS07865	COG2814	Major facilitator Superfamily
QF06_RS07870	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
QF06_RS07885	COG0756	dUTP diphosphatase activity
QF06_RS07920	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
QF06_RS07930	COG3832	glyoxalase III activity
QF06_RS07940	COG0697	spore germination
QF06_RS07945	COG0531	amino acid
QF06_RS07975	COG4195	phage-related replication protein
QF06_RS07985	COG0346	lactoylglutathione lyase activity
QF06_RS07990	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
QF06_RS07995	COG1388	LysM domain
QF06_RS08000	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
QF06_RS08005	COG4224	UPF0291 protein
QF06_RS08010	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
QF06_RS08020	COG3763	UPF0154 protein
QF06_RS08030	COG0785	Cytochrome C biogenesis protein
QF06_RS08035	COG2201	protein-glutamate methylesterase activity
QF06_RS08040	COG4846	Membrane protein involved in cytochrome C biogenesis
QF06_RS08050	COG0071	Belongs to the small heat shock protein (HSP20) family
QF06_RS08065	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
QF06_RS08070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
QF06_RS08090	COG0824	Thioesterase
QF06_RS08100	COG4841	protein insertion into membrane
QF06_RS08105	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
QF06_RS08110	COG1832	CoA-binding protein
QF06_RS08115	COG0187	DNA topoisomerase II activity
QF06_RS08120	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
QF06_RS08130	COG1115	amino acid carrier protein
QF06_RS08135	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
QF06_RS08145	COG5520	Belongs to the glycosyl hydrolase 30 family
QF06_RS08150	COG3507	Belongs to the glycosyl hydrolase 43 family
QF06_RS08155	COG2246	polysaccharide biosynthetic process
QF06_RS08160	COG1210	Utp--glucose-1-phosphate uridylyltransferase
QF06_RS08165	COG0586	Pfam SNARE associated Golgi protein
QF06_RS08170	COG2404	hydrolase activity, acting on ester bonds
QF06_RS08175	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
QF06_RS08180	COG1024	Enoyl-CoA hydratase
QF06_RS08185	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
QF06_RS08190	COG0511	ligase activity, forming carbon-carbon bonds
QF06_RS08195	COG0439	Biotin carboxylase
QF06_RS08200	COG0318	PFAM AMP-dependent synthetase and ligase
QF06_RS08205	COG1960	acyl-CoA dehydrogenase activity
QF06_RS08215	COG1649	PFAM Uncharacterised BCR, COG1649
QF06_RS08225	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
QF06_RS08225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
QF06_RS08235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
QF06_RS08240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
QF06_RS08245	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
QF06_RS08250	COG2027	D-alanyl-D-alanine carboxypeptidase
QF06_RS08255	COG2017	converts alpha-aldose to the beta-anomer
QF06_RS08260	COG0534	Mate efflux family protein
QF06_RS08275	COG0582	viral genome integration into host DNA
QF06_RS08280	COG0166	Belongs to the GPI family
QF06_RS08285	COG0405	Gamma-glutamyltransferase
QF06_RS08290	COG0583	DNA-binding transcription factor activity
QF06_RS08295	COG0604	alcohol dehydrogenase
QF06_RS08300	COG0493	'glutamate synthase
QF06_RS08305	COG0069	glutamate synthase activity
QF06_RS08305	COG0067	glutamate synthase
QF06_RS08305	COG0070	glutamate synthase
QF06_RS08310	COG0583	DNA-binding transcription factor activity
QF06_RS08315	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
QF06_RS08320	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
QF06_RS08330	COG0300	oxidoreductase activity
QF06_RS08335	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
QF06_RS08345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
QF06_RS08360	COG1131	(ABC) transporter
QF06_RS08370	COG2814	Major facilitator Superfamily
QF06_RS08375	COG1070	Carbohydrate kinase
QF06_RS08385	COG0243	molybdopterin cofactor binding
QF06_RS08395	COG2814	Major facilitator Superfamily
QF06_RS08400	COG0673	inositol 2-dehydrogenase activity
QF06_RS08405	COG1082	Xylose isomerase domain protein TIM barrel
QF06_RS08410	COG1609	Transcriptional regulator
QF06_RS08430	COG5278	phosphoserine phosphatase activity
QF06_RS08430	COG0840	transmembrane signaling receptor activity
QF06_RS08435	COG2368	4-hydroxyphenylacetate
QF06_RS08440	COG4305	rare lipoprotein A
QF06_RS08445	COG3619	membrane
QF06_RS08450	COG3866	Pectate lyase
QF06_RS08455	COG2135	peptidase activity
QF06_RS08465	COG2140	Oxalate decarboxylase
QF06_RS08485	COG2720	vancomycin resistance protein
QF06_RS08495	COG3655	Transcriptional regulator
QF06_RS08500	COG3739	integral membrane protein
QF06_RS08505	COG0583	DNA-binding transcription factor activity
QF06_RS08510	COG0697	spore germination
QF06_RS08520	COG0693	protein deglycase activity
QF06_RS08525	COG2367	Beta-lactamase
QF06_RS08540	COG0574	Belongs to the PEP-utilizing enzyme family
QF06_RS08540	COG3848	Pyruvate phosphate dikinase
QF06_RS08545	COG0726	polysaccharide deacetylase
QF06_RS08550	COG2314	TM2 domain
QF06_RS08605	COG0457	Tetratricopeptide repeat
QF06_RS08615	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
QF06_RS08620	COG5444	nuclease activity
QF06_RS08625	COG4282	regulation of fungal-type cell wall biogenesis
QF06_RS08630	COG1231	oxidoreductase activity
QF06_RS08635	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
QF06_RS08640	COG2207	Transcriptional regulator
QF06_RS08640	COG0662	Cupin 2, conserved barrel domain protein
QF06_RS08645	COG0456	acetyltransferase
QF06_RS08650	COG1309	transcriptional regulator
QF06_RS08655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
QF06_RS08660	COG3708	Transcriptional regulator
QF06_RS08665	COG2378	regulation of single-species biofilm formation
QF06_RS08675	COG0640	Transcriptional regulator
QF06_RS08680	COG0741	lytic transglycosylase activity
QF06_RS08685	COG2322	membrane
QF06_RS08700	COG1619	proteins homologs of microcin C7 resistance protein MccF
QF06_RS08705	COG3239	Fatty acid desaturase
QF06_RS08710	COG4585	Histidine kinase
QF06_RS08715	COG2197	response regulator
QF06_RS08720	COG3584	3D domain protein
QF06_RS08720	COG1388	LysM domain
QF06_RS08725	COG0514	ATP-dependent DNA helicase (RecQ)
QF06_RS08735	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
QF06_RS08740	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
QF06_RS08755	COG0071	Belongs to the small heat shock protein (HSP20) family
QF06_RS08780	COG1012	belongs to the aldehyde dehydrogenase family
QF06_RS08785	COG1657	PFAM Prenyltransferase squalene oxidase
QF06_RS08790	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
QF06_RS08795	COG0733	neurotransmitter:sodium symporter activity
QF06_RS08800	COG0385	Bile acid
QF06_RS08805	COG0508	dehydrogenase complex catalyzes the overall conversion of
QF06_RS08810	COG0567	Dehydrogenase, E1 component
QF06_RS08815	COG4548	von Willebrand factor, type A
QF06_RS08820	COG0714	Associated with various cellular activities
QF06_RS08825	COG2032	superoxide dismutase activity
QF06_RS08830	COG1388	LysM domain
QF06_RS08830	COG0791	NLP P60 protein
QF06_RS08835	COG1819	glycosyl
QF06_RS08840	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
QF06_RS08845	COG0534	Mate efflux family protein
QF06_RS08850	COG1366	Belongs to the anti-sigma-factor antagonist family
QF06_RS08855	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
QF06_RS08860	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
QF06_RS08870	COG2962	Rard protein
QF06_RS08885	COG2610	gluconate transmembrane transporter activity
QF06_RS08890	COG1942	4-Oxalocrotonate Tautomerase
QF06_RS08895	COG1733	regulation of RNA biosynthetic process
QF06_RS08900	COG0778	Nitroreductase
QF06_RS08905	COG0400	carboxylic ester hydrolase activity
QF06_RS08910	COG0346	lactoylglutathione lyase activity
QF06_RS08920	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
QF06_RS08925	COG3409	Peptidoglycan-binding domain 1 protein
QF06_RS08925	COG0793	Belongs to the peptidase S41A family
QF06_RS08930	COG2226	methyltransferase
QF06_RS08940	COG1876	peptidase activity
QF06_RS08945	COG0813	purine-nucleoside phosphorylase activity
QF06_RS08955	COG0671	phosphoesterase, PA-phosphatase related
QF06_RS08970	COG4479	Belongs to the UPF0346 family
QF06_RS08980	COG1509	lysine 2,3-aminomutase activity
QF06_RS08985	COG0456	acetyltransferase
QF06_RS08990	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
QF06_RS08995	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
QF06_RS09000	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
QF06_RS09005	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
QF06_RS09015	COG0456	acetyltransferase
QF06_RS09020	COG0463	Glycosyl transferase, family 2
QF06_RS09035	COG4641	Protein conserved in bacteria
QF06_RS09040	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
QF06_RS09045	COG1086	Polysaccharide biosynthesis protein
QF06_RS09050	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
QF06_RS09055	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
QF06_RS09060	COG1846	Transcriptional regulator
QF06_RS09065	COG0534	Mate efflux family protein
QF06_RS09075	COG4698	Protein conserved in bacteria
QF06_RS09080	COG2755	lipolytic protein G-D-S-L family
QF06_RS09085	COG1999	signal sequence binding
QF06_RS09095	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
QF06_RS09100	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
QF06_RS09105	COG1272	protein, Hemolysin III
QF06_RS09110	COG0204	Acyl-transferase
QF06_RS09115	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
QF06_RS09120	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
QF06_RS09130	COG2136	Putative SAM-dependent methyltransferase
QF06_RS09130	COG2521	methyltransferase
QF06_RS09140	COG0129	dihydroxy-acid dehydratase activity
QF06_RS09145	COG1413	lyase activity
QF06_RS09150	COG1418	mRNA catabolic process
QF06_RS09155	COG0386	Belongs to the glutathione peroxidase family
QF06_RS09160	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
QF06_RS09165	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
QF06_RS09170	COG1278	Cold shock
QF06_RS09190	COG0328	RNA-DNA hybrid ribonuclease activity
QF06_RS09195	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
QF06_RS09200	COG0328	RNA-DNA hybrid ribonuclease activity
QF06_RS09210	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
QF06_RS09220	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
QF06_RS09225	COG1755	Isoprenylcysteine carboxyl methyltransferase
QF06_RS09230	COG3424	synthase
QF06_RS09235	COG2233	PERMEase
QF06_RS09240	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
QF06_RS09245	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
QF06_RS09255	COG0800	Aldolase
QF06_RS09260	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
QF06_RS09265	COG1609	Transcriptional regulator
QF06_RS09270	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
QF06_RS09275	COG1028	Short-chain dehydrogenase reductase Sdr
QF06_RS09280	COG1199	ATP-dependent helicase activity
QF06_RS09290	COG0116	Belongs to the methyltransferase superfamily
QF06_RS09300	COG4474	Belongs to the UPF0398 family
QF06_RS09305	COG3359	exonuclease
QF06_RS09310	COG1111	helicase
QF06_RS09310	COG1205	dead DEAH box helicase
QF06_RS09315	COG2190	(PTS) system
QF06_RS09320	COG0071	Belongs to the small heat shock protein (HSP20) family
QF06_RS09355	COG3331	DNA recombination
QF06_RS09360	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
QF06_RS09360	COG4499	WXG100 protein secretion system (Wss), protein YukC
QF06_RS09370	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
QF06_RS09375	COG3935	DnaD domain protein
QF06_RS09380	COG0017	Asparaginyl-tRNA synthetase
QF06_RS09385	COG0436	Aminotransferase
QF06_RS09390	COG5353	protein conserved in bacteria
QF06_RS09395	COG1199	ATP-dependent helicase activity
QF06_RS09395	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
QF06_RS09400	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
QF06_RS09405	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
QF06_RS09410	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
QF06_RS09415	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
QF06_RS09415	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
QF06_RS09420	COG0617	tRNA 3'-terminal CCA addition
QF06_RS09425	COG0438	transferase activity, transferring glycosyl groups
QF06_RS09430	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
QF06_RS09435	COG1803	Methylglyoxal synthase
QF06_RS09440	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
QF06_RS09445	COG1694	Mazg nucleotide pyrophosphohydrolase
QF06_RS09450	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
QF06_RS09460	COG4347	Protein of unknown function (DUF1405)
QF06_RS09465	COG2010	Cytochrome c
QF06_RS09465	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
QF06_RS09470	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
QF06_RS09475	COG0723	plastoquinol--plastocyanin reductase activity
QF06_RS09485	COG5582	Belongs to the UPF0302 family
QF06_RS09490	COG0457	Tetratricopeptide repeat
QF06_RS09495	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
QF06_RS09500	COG0287	Prephenate dehydrogenase
QF06_RS09505	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
QF06_RS09515	COG0133	tryptophan synthase activity
QF06_RS09520	COG0135	phosphoribosylanthranilate isomerase activity
QF06_RS09530	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
QF06_RS09535	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
QF06_RS09540	COG4401	Chorismate mutase type I
QF06_RS09545	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
QF06_RS09550	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
QF06_RS09555	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
QF06_RS09560	COG0105	UTP biosynthetic process
QF06_RS09565	COG0142	geranyltranstransferase activity
QF06_RS09570	COG2226	methyltransferase
QF06_RS09575	COG0142	geranyltranstransferase activity
QF06_RS09585	COG0302	gtp cyclohydrolase
QF06_RS09590	COG0776	regulation of translation
QF06_RS09595	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
QF06_RS09610	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
QF06_RS09615	COG1160	GTP binding
QF06_RS09635	COG1304	FMN binding
QF06_RS09640	COG0539	negative regulation of cytoplasmic translation
QF06_RS09645	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
QF06_RS09650	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
QF06_RS09655	COG2959	enzyme of heme biosynthesis
QF06_RS09660	COG3409	Peptidoglycan-binding domain 1 protein
QF06_RS09660	COG3773	Cell wall hydrolase
QF06_RS09665	COG2339	peptidase activity
QF06_RS09670	COG0492	ferredoxin-NADP+ reductase activity
QF06_RS09675	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
QF06_RS09680	COG4862	establishment of competence for transformation
QF06_RS09685	COG1408	metallophosphoesterase
QF06_RS09695	COG1388	LysM domain
QF06_RS09700	COG1266	CAAX protease self-immunity
QF06_RS09705	COG0514	ATP-dependent DNA helicase (RecQ)
QF06_RS09710	COG4955	Helix-turn-helix domain
QF06_RS09715	COG1141	Ferredoxin
QF06_RS09720	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
QF06_RS09725	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
QF06_RS09730	COG0710	3-dehydroquinate dehydratase activity
QF06_RS09740	COG1595	DNA-templated transcription, initiation
QF06_RS09745	COG5002	protein histidine kinase activity
QF06_RS09750	COG0745	RESPONSE REGULATOR receiver
QF06_RS09755	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
QF06_RS09760	COG1333	cytochrome c biogenesis protein
QF06_RS09765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
QF06_RS09770	COG1187	pseudouridine synthase activity
QF06_RS09775	COG0700	Nucleoside recognition
QF06_RS09780	COG2715	membrane protein required for spore maturation
QF06_RS09785	COG1686	Belongs to the peptidase S11 family
QF06_RS09795	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
QF06_RS09800	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
QF06_RS09805	COG1547	Domain of unknown function (DUF309)
QF06_RS09810	COG0456	acetyltransferase
QF06_RS09815	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
QF06_RS09820	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
QF06_RS09820	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
QF06_RS09825	COG0307	riboflavin synthase, alpha
QF06_RS09830	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
QF06_RS09830	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
QF06_RS09840	COG0681	Belongs to the peptidase S26 family
QF06_RS09845	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
QF06_RS09855	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
QF06_RS09860	COG4086	secreted protein
QF06_RS09865	COG0019	diaminopimelate decarboxylase activity
QF06_RS09870	COG0697	spore germination
QF06_RS09885	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
QF06_RS09905	COG1191	sigma factor activity
QF06_RS09910	COG2172	sigma factor antagonist activity
QF06_RS09915	COG1366	Belongs to the anti-sigma-factor antagonist family
QF06_RS09920	COG1686	Belongs to the peptidase S11 family
QF06_RS09925	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
QF06_RS09930	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
QF06_RS09935	COG4974	Belongs to the 'phage' integrase family
QF06_RS09945	COG0735	belongs to the Fur family
QF06_RS09950	COG1300	Membrane
QF06_RS09960	COG0281	malic enzyme
QF06_RS09965	COG1757	Na H antiporter
QF06_RS09970	COG1027	Aspartate ammonia-lyase
QF06_RS09975	COG0252	asparaginase activity
QF06_RS09980	COG1396	sequence-specific DNA binding
QF06_RS09985	COG1379	DNA repair
QF06_RS09990	COG0494	nUDIX hydrolase
QF06_RS10000	COG0667	Aldo Keto reductase
QF06_RS10010	COG1073	alpha beta
QF06_RS10020	COG4918	Iron-sulphur cluster biosynthesis
QF06_RS10025	COG0456	acetyltransferase
QF06_RS10025	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
QF06_RS10030	COG2329	Antibiotic biosynthesis monooxygenase
QF06_RS10035	COG0456	acetyltransferase
QF06_RS10045	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
QF06_RS10055	COG2211	Major facilitator Superfamily
QF06_RS10060	COG0346	lactoylglutathione lyase activity
QF06_RS10065	COG1072	(Pantothenic acid kinase))
QF06_RS10070	COG3048	D-serine ammonia-lyase activity
QF06_RS10075	COG0300	oxidoreductase activity
QF06_RS10080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
QF06_RS10085	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
QF06_RS10090	COG4187	Peptidase family M20/M25/M40
QF06_RS10095	COG1902	pentaerythritol trinitrate reductase activity
QF06_RS10100	COG0596	Alpha beta hydrolase
QF06_RS10110	COG1234	tRNA 3'-trailer cleavage
QF06_RS10115	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
QF06_RS10120	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
QF06_RS10125	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
QF06_RS10135	COG0706	membrane insertase activity
QF06_RS10140	COG3361	conserved protein (COG2071)
QF06_RS10145	COG2195	Cleaves the N-terminal amino acid of tripeptides
QF06_RS10150	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
QF06_RS10155	COG0346	lactoylglutathione lyase activity
QF06_RS10160	COG1376	ErfK ybiS ycfS ynhG family protein
QF06_RS10165	COG4129	membrane
QF06_RS10170	COG1126	abc transporter atp-binding protein
QF06_RS10175	COG0765	amino acid transport
QF06_RS10180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
QF06_RS10190	COG1597	lipid kinase activity
QF06_RS10195	COG2814	Major facilitator Superfamily
QF06_RS10200	COG4978	Transcriptional regulator
QF06_RS10200	COG0789	Transcriptional regulator
QF06_RS10205	COG0508	dehydrogenase complex catalyzes the overall conversion of
QF06_RS10210	COG0022	dehydrogenase e1 component
QF06_RS10215	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
QF06_RS10220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
QF06_RS10225	COG3426	butyrate kinase activity
QF06_RS10230	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
QF06_RS10235	COG0280	phosphate acetyltransferase
QF06_RS10240	COG3290	protein histidine kinase activity
QF06_RS10240	COG3829	transcription factor binding
QF06_RS10250	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
QF06_RS10255	COG2079	MmgE PrpD family protein
QF06_RS10260	COG0372	Belongs to the citrate synthase family
QF06_RS10265	COG1960	acyl-CoA dehydrogenase activity
QF06_RS10270	COG1250	3-hydroxyacyl-CoA dehydrogenase
QF06_RS10275	COG0183	Belongs to the thiolase family
QF06_RS10280	COG0584	glycerophosphoryl diester phosphodiesterase
QF06_RS10285	COG0860	N-Acetylmuramoyl-L-alanine amidase
QF06_RS10295	COG1902	pentaerythritol trinitrate reductase activity
QF06_RS10300	COG0745	RESPONSE REGULATOR receiver
QF06_RS10305	COG0750	zinc metalloprotease
QF06_RS10310	COG0497	DNA recombination
QF06_RS10315	COG1438	arginine binding
QF06_RS10320	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
QF06_RS10325	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
QF06_RS10330	COG0142	geranyltranstransferase activity
QF06_RS10335	COG1722	exodeoxyribonuclease VII activity
QF06_RS10340	COG1570	exodeoxyribonuclease VII activity
QF06_RS10345	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
QF06_RS10350	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
QF06_RS10355	COG1302	Protein conserved in bacteria
QF06_RS10360	COG0439	Biotin carboxylase
QF06_RS10365	COG0511	ligase activity, forming carbon-carbon bonds
QF06_RS10405	COG3854	ATPases associated with a variety of cellular activities
QF06_RS10415	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
QF06_RS10420	COG0006	proline dipeptidase activity
QF06_RS10425	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
QF06_RS10435	COG3872	metal-dependent enzyme
QF06_RS10445	COG1752	Esterase of the alpha-beta hydrolase superfamily
QF06_RS10450	COG1321	iron dependent repressor
QF06_RS10455	COG0095	Lipoate-protein ligase
QF06_RS10460	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
QF06_RS10465	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
QF06_RS10470	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
QF06_RS10475	COG0404	The glycine cleavage system catalyzes the degradation of glycine
QF06_RS10480	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
QF06_RS10495	COG1396	sequence-specific DNA binding
QF06_RS10505	COG0681	Belongs to the peptidase S26 family
QF06_RS10530	COG4940	Competence protein ComGF
QF06_RS10540	COG4970	Tfp pilus assembly protein FimT
QF06_RS10545	COG4537	Required for transformation and DNA binding
QF06_RS10550	COG1459	type II secretion system
QF06_RS10555	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
QF06_RS10560	COG0598	Magnesium transport protein CorA
QF06_RS10565	COG1253	flavin adenine dinucleotide binding
QF06_RS10570	COG1366	Belongs to the anti-sigma-factor antagonist family
QF06_RS10580	COG1393	Belongs to the ArsC family
QF06_RS10590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
QF06_RS10600	COG0011	TIGRFAM Protein of
QF06_RS10610	COG2866	Carboxypeptidase
QF06_RS10615	COG1368	sulfuric ester hydrolase activity
QF06_RS10625	COG4483	Protein conserved in bacteria
QF06_RS10630	COG0457	Tetratricopeptide repeat
QF06_RS10630	COG0705	Rhomboid family
QF06_RS10635	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
QF06_RS10645	COG0438	transferase activity, transferring glycosyl groups
QF06_RS10660	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
QF06_RS10665	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
QF06_RS10670	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
QF06_RS10675	COG0581	inorganic phosphate transmembrane transporter activity
QF06_RS10680	COG0573	inorganic phosphate transmembrane transporter activity
QF06_RS10685	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
QF06_RS10690	COG0768	penicillin binding
QF06_RS10695	COG0477	Major facilitator Superfamily
QF06_RS10700	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
QF06_RS10705	COG2839	Protein conserved in bacteria
QF06_RS10710	COG5521	maltodextrose utilization protein MalA
QF06_RS10715	COG1388	LysM domain
QF06_RS10720	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
QF06_RS10725	COG4709	membrane
QF06_RS10730	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
QF06_RS10735	COG0735	belongs to the Fur family
QF06_RS10740	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
QF06_RS10750	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
QF06_RS10755	COG0513	Belongs to the DEAD box helicase family
QF06_RS10765	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
QF06_RS10770	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
QF06_RS10775	COG2384	SAM-dependent methyltransferase
QF06_RS10780	COG2010	Cytochrome c
QF06_RS10785	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
QF06_RS10790	COG0358	DNA primase activity
QF06_RS10795	COG1671	Belongs to the UPF0178 family
QF06_RS10800	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
QF06_RS10805	COG0517	IMP dehydrogenase activity
QF06_RS10810	COG0751	glycine-tRNA ligase activity
QF06_RS10815	COG0752	glycyl-tRNA synthetase alpha subunit
QF06_RS10820	COG1381	Involved in DNA repair and RecF pathway recombination
QF06_RS10825	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
QF06_RS10830	COG0295	cytidine deaminase activity
QF06_RS10835	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
QF06_RS10840	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
QF06_RS10845	COG1480	7TM receptor with intracellular HD hydrolase
QF06_RS10850	COG1702	phosphate starvation-inducible protein PhoH
QF06_RS10855	COG0561	phosphatase activity
QF06_RS10870	COG4864	UPF0365 protein
QF06_RS10875	COG1030	water channel activity
QF06_RS10880	COG1610	YqeY-like protein
QF06_RS10890	COG1283	sodium-dependent phosphate transmembrane transporter activity
QF06_RS10895	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
QF06_RS10900	COG1385	rRNA (uridine-N3-)-methyltransferase activity
QF06_RS10905	COG2264	protein methyltransferase activity
QF06_RS10910	COG0484	heat shock protein binding
QF06_RS10915	COG0443	Heat shock 70 kDa protein
QF06_RS10920	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
QF06_RS10925	COG1420	regulation of RNA biosynthetic process
QF06_RS10930	COG0635	Involved in the biosynthesis of porphyrin-containing compound
QF06_RS10945	COG0860	N-Acetylmuramoyl-L-alanine amidase
QF06_RS10950	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
QF06_RS10955	COG0268	Binds directly to 16S ribosomal RNA
QF06_RS10960	COG1466	dna polymerase III delta subunit
QF06_RS10970	COG2333	competence protein COMEC
QF06_RS10970	COG0658	competence protein
QF06_RS10975	COG2131	deaminase
QF06_RS10980	COG1555	photosystem II stabilization
QF06_RS10980	COG1596	polysaccharide export
QF06_RS10985	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
QF06_RS10990	COG2226	methyltransferase
QF06_RS10995	COG0799	negative regulation of ribosome biogenesis
QF06_RS11000	COG1713	HD superfamily hydrolase involved in NAD metabolism
QF06_RS11005	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
QF06_RS11010	COG1534	Rna-binding protein
QF06_RS11015	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
QF06_RS11020	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
QF06_RS11025	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
QF06_RS11035	COG2755	lipolytic protein G-D-S-L family
QF06_RS11040	COG3409	Peptidoglycan-binding domain 1 protein
QF06_RS11040	COG5632	N-Acetylmuramoyl-L-alanine amidase
QF06_RS11045	COG0398	Pfam SNARE associated Golgi protein
QF06_RS11050	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
QF06_RS11060	COG3209	COG3209 Rhs family protein
QF06_RS11070	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
QF06_RS11075	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
QF06_RS11080	COG0798	PFAM Bile acid sodium symporter
QF06_RS11085	COG0346	lactoylglutathione lyase activity
QF06_RS11090	COG0640	Transcriptional regulator
QF06_RS11095	COG3403	YqcI/YcgG family
QF06_RS11100	COG0457	Tetratricopeptide repeat
QF06_RS11110	COG5444	nuclease activity
QF06_RS11130	COG3409	Peptidoglycan-binding domain 1 protein
QF06_RS11130	COG5632	N-Acetylmuramoyl-L-alanine amidase
QF06_RS11135	COG4824	toxin secretion phage lysis holin
QF06_RS11165	COG3778	Protein conserved in bacteria
QF06_RS11170	COG3299	homolog of phage Mu protein gp47
QF06_RS11175	COG3628	GPW Gp25 family protein
QF06_RS11185	COG4193	domain, Protein
QF06_RS11190	COG1652	LysM domain
QF06_RS11195	COG3953	SLT domain
QF06_RS11195	COG5280	Phage tail tape measure protein TP901
QF06_RS11250	COG4653	Phage capsid family
QF06_RS11255	COG0338	D12 class N6 adenine-specific DNA methyltransferase
QF06_RS11265	COG2369	cell adhesion
QF06_RS11270	COG5518	Phage portal protein
QF06_RS11275	COG1783	phage Terminase large subunit
QF06_RS11280	COG5484	DNA packaging
QF06_RS11290	COG3677	Transposase
QF06_RS11305	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
QF06_RS11310	COG1484	DNA-dependent DNA replication
QF06_RS11315	COG3935	DnaD domain protein
QF06_RS11320	COG3723	Recombinational DNA repair protein, rece pathway
QF06_RS11325	COG5377	YqaJ viral recombinase family
QF06_RS11345	COG1476	TRANSCRIPTIONal
QF06_RS11350	COG3620	sequence-specific DNA binding
QF06_RS11355	COG0563	adenylate kinase activity
QF06_RS11360	COG2856	Zn peptidase
QF06_RS11370	COG3223	Belongs to the PsiE family
QF06_RS11375	COG0642	Histidine kinase
QF06_RS11375	COG5002	protein histidine kinase activity
QF06_RS11380	COG0745	RESPONSE REGULATOR receiver
QF06_RS11385	COG2311	Membrane
QF06_RS11390	COG0454	-acetyltransferase
QF06_RS11395	COG2249	NAD(P)H dehydrogenase (quinone) activity
QF06_RS11405	COG0730	response to heat
QF06_RS11410	COG0425	Belongs to the sulfur carrier protein TusA family
QF06_RS11415	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
QF06_RS11415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
QF06_RS11425	COG0425	Belongs to the sulfur carrier protein TusA family
QF06_RS11425	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
QF06_RS11430	COG2210	Belongs to the sulfur carrier protein TusA family
QF06_RS11435	COG1937	Protein conserved in bacteria
QF06_RS11440	COG0662	Cupin 2, conserved barrel domain protein
QF06_RS11445	COG0789	Transcriptional regulator
QF06_RS11445	COG4978	Transcriptional regulator
QF06_RS11450	COG2814	Major facilitator Superfamily
QF06_RS11455	COG0456	acetyltransferase
QF06_RS11460	COG1253	flavin adenine dinucleotide binding
QF06_RS11465	COG0697	spore germination
QF06_RS11470	COG0583	DNA-binding transcription factor activity
QF06_RS11475	COG2072	flavoprotein involved in K transport
QF06_RS11480	COG1230	cation diffusion facilitator family transporter
QF06_RS11485	COG1942	4-Oxalocrotonate Tautomerase
QF06_RS11490	COG0583	DNA-binding transcription factor activity
QF06_RS11500	COG1114	Component of the transport system for branched-chain amino acids
QF06_RS11505	COG1687	branched-chain amino acid
QF06_RS11510	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
QF06_RS11515	COG1522	sequence-specific DNA binding
QF06_RS11520	COG2732	(Barnase) inhibitor
QF06_RS11525	COG2124	cytochrome p450
QF06_RS11530	COG1335	isochorismatase
QF06_RS11540	COG2318	DinB family
QF06_RS11550	COG2070	2-Nitropropane dioxygenase
QF06_RS11555	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
QF06_RS11565	COG2186	Transcriptional regulator
QF06_RS11575	COG1028	Short-chain dehydrogenase reductase Sdr
QF06_RS11580	COG3958	Transketolase
QF06_RS11585	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
QF06_RS11590	COG0477	Major facilitator Superfamily
QF06_RS11595	COG1846	Transcriptional regulator
QF06_RS11600	COG3443	Belongs to the bacterial solute-binding protein 9 family
QF06_RS11605	COG1595	DNA-templated transcription, initiation
QF06_RS11610	COG0667	Aldo Keto reductase
QF06_RS11615	COG2851	Citrate transporter
QF06_RS11620	COG0583	DNA-binding transcription factor activity
QF06_RS11625	COG2828	Protein conserved in bacteria
QF06_RS11630	COG3409	Peptidoglycan-binding domain 1 protein
QF06_RS11635	COG5566	PFAM Mor transcription activator
QF06_RS11640	COG0596	Alpha beta hydrolase
QF06_RS11645	COG4991	sh3 domain protein
QF06_RS11650	COG4991	sh3 domain protein
QF06_RS11655	COG0346	lactoylglutathione lyase activity
QF06_RS11665	COG5577	PFAM Coat F domain
QF06_RS11670	COG1063	alcohol dehydrogenase
QF06_RS11680	COG5577	PFAM Coat F domain
QF06_RS11685	COG0789	Transcriptional regulator
QF06_RS11695	COG1064	alcohol dehydrogenase
QF06_RS11700	COG0693	protein deglycase activity
QF06_RS11705	COG1621	beta-fructofuranosidase activity
QF06_RS11710	COG3716	PTS system mannose fructose sorbose family IID component
QF06_RS11715	COG3715	PTS system
QF06_RS11720	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
QF06_RS11725	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
QF06_RS11730	COG3933	PFAM sigma-54 factor interaction domain-containing protein
QF06_RS11730	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
QF06_RS11735	COG1113	amino acid transport
QF06_RS11740	COG1280	lysine exporter protein (LysE YggA)
QF06_RS11745	COG1378	Sugar-specific transcriptional regulator TrmB
QF06_RS11750	COG1595	DNA-templated transcription, initiation
QF06_RS11760	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
QF06_RS11760	COG2755	lipolytic protein G-D-S-L family
QF06_RS11770	COG2124	cytochrome p450
QF06_RS11770	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
QF06_RS11775	COG1309	transcriptional regulator
QF06_RS11780	COG2226	methyltransferase
QF06_RS11790	COG2116	formate transmembrane transporter activity
QF06_RS11795	COG5609	conserved protein (DUF2294)
QF06_RS11800	COG3383	formate dehydrogenase (NAD+) activity
QF06_RS11805	COG2427	Protein of unknown function (DUF1641)
QF06_RS11815	COG0626	cystathionine gamma-synthase activity
QF06_RS11820	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
QF06_RS11825	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
QF06_RS11830	COG2226	methyltransferase
QF06_RS11845	COG0768	penicillin binding
QF06_RS11850	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
QF06_RS11855	COG0572	uridine kinase
QF06_RS11860	COG0826	peptidase U32
QF06_RS11865	COG0826	peptidase U32
QF06_RS11870	COG4122	O-methyltransferase activity
QF06_RS11875	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
QF06_RS11880	COG3906	Belongs to the UPF0473 family
QF06_RS11885	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
QF06_RS11890	COG4472	Bacterial protein of unknown function (DUF965)
QF06_RS11895	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
QF06_RS11900	COG0628	permease
QF06_RS11905	COG1126	abc transporter atp-binding protein
QF06_RS11910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
QF06_RS11915	COG0765	amino acid transport
QF06_RS11920	COG0765	amino acid transport
QF06_RS11930	COG3881	PFAM PRC-barrel domain
QF06_RS11935	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
QF06_RS11940	COG0457	Tetratricopeptide repeat
QF06_RS11945	COG0482	sulfurtransferase activity
QF06_RS11950	COG1104	cysteine desulfurase activity
QF06_RS11955	COG1959	2 iron, 2 sulfur cluster binding
QF06_RS11960	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
QF06_RS11965	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
QF06_RS11970	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
QF06_RS11975	COG0124	histidyl-tRNA synthetase
QF06_RS11980	COG3103	Sh3 type 3 domain protein
QF06_RS11980	COG4991	sh3 domain protein
QF06_RS11980	COG0860	N-Acetylmuramoyl-L-alanine amidase
QF06_RS11985	COG1490	D-aminoacyl-tRNA deacylase activity
QF06_RS11990	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
QF06_RS11995	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
QF06_RS12000	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
QF06_RS12000	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
QF06_RS12005	COG5416	Lipopolysaccharide assembly protein A domain
QF06_RS12010	COG0490	domain, Protein
QF06_RS12015	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
QF06_RS12015	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
QF06_RS12025	COG2244	polysaccharide biosynthetic process
QF06_RS12030	COG2323	membrane
QF06_RS12040	COG1862	Preprotein translocase
QF06_RS12045	COG0343	queuine tRNA-ribosyltransferase activity
QF06_RS12050	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
QF06_RS12060	COG2255	four-way junction helicase activity
QF06_RS12065	COG0632	four-way junction helicase activity
QF06_RS12075	COG2814	Major facilitator Superfamily
QF06_RS12080	COG0673	inositol 2-dehydrogenase activity
QF06_RS12085	COG2112	serine threonine protein kinase
QF06_RS12100	COG1115	amino acid carrier protein
QF06_RS12105	COG0217	transcriptional regulatory protein
QF06_RS12115	COG1388	LysM domain
QF06_RS12120	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
QF06_RS12125	COG0157	Belongs to the NadC ModD family
QF06_RS12130	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
QF06_RS12135	COG1104	cysteine desulfurase activity
QF06_RS12140	COG1827	regulation of RNA biosynthetic process
QF06_RS12145	COG0077	Prephenate dehydratase
QF06_RS12150	COG4492	Belongs to the UPF0735 family
QF06_RS12155	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
QF06_RS12160	COG3290	protein histidine kinase activity
QF06_RS12165	COG0211	Belongs to the bacterial ribosomal protein bL27 family
QF06_RS12170	COG2868	ribosomal protein
QF06_RS12175	COG0261	This protein binds to 23S rRNA in the presence of protein L20
QF06_RS12180	COG1994	Peptidase M50
QF06_RS12185	COG0739	heme binding
QF06_RS12190	COG2894	cell division
QF06_RS12195	COG0850	regulation of cytokinetic process
QF06_RS12200	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
QF06_RS12210	COG1077	Cell shape determining protein MreB Mrl
QF06_RS12215	COG2003	Belongs to the UPF0758 family
QF06_RS12220	COG0424	maF-like protein
QF06_RS12230	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
QF06_RS12235	COG0285	dihydrofolate synthase activity
QF06_RS12240	COG0525	valine-tRNA ligase activity
QF06_RS12250	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
QF06_RS12255	COG1388	LysM domain
QF06_RS12260	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
QF06_RS12265	COG0113	porphobilinogen synthase activity
QF06_RS12270	COG1587	Uroporphyrinogen-III synthase
QF06_RS12275	COG0181	hydroxymethylbilane synthase activity
QF06_RS12280	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
QF06_RS12285	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
QF06_RS12295	COG0218	Necessary for normal cell division and for the maintenance of normal septation
QF06_RS12300	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
QF06_RS12305	COG0470	DNA polymerase III
QF06_RS12305	COG1067	ATP-dependent peptidase activity
QF06_RS12310	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
QF06_RS12315	COG0544	peptidyl-prolyl cis-trans isomerase activity
QF06_RS12320	COG0457	Tetratricopeptide repeat
QF06_RS12320	COG1477	protein flavinylation
QF06_RS12325	COG0066	3-isopropylmalate dehydratase activity
QF06_RS12330	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
QF06_RS12335	COG0473	3-isopropylmalate dehydrogenase activity
QF06_RS12340	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
QF06_RS12345	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
QF06_RS12350	COG0440	acetolactate synthase activity
QF06_RS12355	COG0028	Belongs to the TPP enzyme family
QF06_RS12365	COG0454	-acetyltransferase
QF06_RS12370	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
QF06_RS12380	COG0622	Phosphoesterase
QF06_RS12385	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
QF06_RS12390	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
QF06_RS12395	COG5401	PFAM Sporulation and spore germination
QF06_RS12400	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
QF06_RS12405	COG1846	Transcriptional regulator
QF06_RS12410	COG2197	response regulator
QF06_RS12415	COG0824	Thioesterase
QF06_RS12420	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
QF06_RS12425	COG1053	succinate dehydrogenase
QF06_RS12430	COG2009	succinate dehydrogenase
QF06_RS12435	COG1719	4-vinyl reductase, 4VR
QF06_RS12440	COG0527	aspartate kinase activity
QF06_RS12445	COG0322	excinuclease ABC activity
QF06_RS12450	COG3118	belongs to the thioredoxin family
QF06_RS12455	COG3534	alpha-L-arabinofuranosidase
QF06_RS12460	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
QF06_RS12465	COG2086	electron transfer activity
QF06_RS12470	COG1024	Enoyl-CoA hydratase
QF06_RS12475	COG1309	transcriptional regulator
QF06_RS12480	COG0318	PFAM AMP-dependent synthetase and ligase
QF06_RS12485	COG3766	membrane
QF06_RS12490	COG1193	negative regulation of DNA recombination
QF06_RS12495	COG1796	DNA polymerase
QF06_RS12495	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
QF06_RS12500	COG1286	toxin biosynthetic process
QF06_RS12505	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
QF06_RS12510	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
QF06_RS12515	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
QF06_RS12515	COG0072	phenylalanine-tRNA ligase activity
QF06_RS12520	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
QF06_RS12530	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
QF06_RS12540	COG3835	regulator
QF06_RS12545	COG0277	FAD linked oxidase domain protein
QF06_RS12550	COG0247	lactate metabolic process
QF06_RS12555	COG0346	lactoylglutathione lyase activity
QF06_RS12560	COG1966	Carbon starvation protein
QF06_RS12565	COG3534	alpha-L-arabinofuranosidase
QF06_RS12570	COG0395	ABC-type sugar transport system, permease component
QF06_RS12575	COG1175	transmembrane transport
QF06_RS12580	COG1653	transport
QF06_RS12585	COG0371	Dehydrogenase
QF06_RS12590	COG0647	UMP catabolic process
QF06_RS12595	COG0235	Class ii aldolase
QF06_RS12600	COG1069	ribulokinase activity
QF06_RS12605	COG2160	L-arabinose isomerase activity
QF06_RS12610	COG3507	Belongs to the glycosyl hydrolase 43 family
QF06_RS12615	COG1363	Peptidase, m42
QF06_RS12625	COG3326	Membrane
QF06_RS12630	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
QF06_RS12635	COG0291	Belongs to the bacterial ribosomal protein bL35 family
QF06_RS12640	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
QF06_RS12650	COG1346	cytolysis
QF06_RS12655	COG1380	Effector of murein hydrolase LrgA
QF06_RS12660	COG3279	Response regulator of the LytR AlgR family
QF06_RS12665	COG3275	phosphorelay sensor kinase activity
QF06_RS12670	COG1011	Hydrolase
QF06_RS12675	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
QF06_RS12685	COG0398	Pfam SNARE associated Golgi protein
QF06_RS12690	COG1484	DNA-dependent DNA replication
QF06_RS12695	COG3611	Membrane attachment protein
QF06_RS12700	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
QF06_RS12705	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
QF06_RS12710	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
QF06_RS12715	COG1733	regulation of RNA biosynthetic process
QF06_RS12720	COG2814	Major facilitator Superfamily
QF06_RS12725	COG0656	L-ascorbic acid biosynthetic process
QF06_RS12730	COG0237	dephospho-CoA kinase activity
QF06_RS12735	COG1971	Probably functions as a manganese efflux pump
QF06_RS12740	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
QF06_RS12745	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
QF06_RS12745	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
QF06_RS12750	COG5002	protein histidine kinase activity
QF06_RS12755	COG0745	RESPONSE REGULATOR receiver
QF06_RS12760	COG0039	L-malate dehydrogenase activity
QF06_RS12765	COG0538	isocitrate dehydrogenase activity
QF06_RS12770	COG0372	Belongs to the citrate synthase family
QF06_RS12775	COG2707	UPF0756 membrane protein
QF06_RS12780	COG0628	permease
QF06_RS12785	COG3030	protein affecting phage T7 exclusion by the F plasmid
QF06_RS12790	COG0469	pyruvate kinase activity
QF06_RS12795	COG0205	6-phosphofructokinase activity
QF06_RS12800	COG0825	malonyl-CoA metabolic process
QF06_RS12805	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
QF06_RS12810	COG0281	malic enzyme
QF06_RS12815	COG0587	DNA-directed DNA polymerase activity
QF06_RS12835	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
QF06_RS12845	COG4109	DRTGG domain
QF06_RS12850	COG0730	response to heat
QF06_RS12855	COG1473	amidohydrolase
QF06_RS12860	COG0196	riboflavin kinase activity
QF06_RS12865	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
QF06_RS12870	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
QF06_RS12875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
QF06_RS12880	COG1126	abc transporter atp-binding protein
QF06_RS12885	COG0765	amino acid transport
QF06_RS12890	COG0765	amino acid transport
QF06_RS12895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
QF06_RS12900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
QF06_RS12905	COG0454	-acetyltransferase
QF06_RS12910	COG0583	DNA-binding transcription factor activity
QF06_RS12915	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
QF06_RS12920	COG1028	Short-chain dehydrogenase reductase Sdr
QF06_RS12925	COG0165	Argininosuccinate lyase
QF06_RS12930	COG0137	argininosuccinate synthase activity
QF06_RS12935	COG0521	Mo-molybdopterin cofactor biosynthetic process
QF06_RS12940	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
QF06_RS12945	COG0827	DNA restriction-modification system
QF06_RS12950	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
QF06_RS12955	COG3874	Sporulation protein YtfJ
QF06_RS12965	COG1714	RDD family
QF06_RS12970	COG0616	signal peptide processing
QF06_RS12975	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
QF06_RS12980	COG1574	metal-dependent hydrolase with the TIM-barrel fold
QF06_RS12985	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
QF06_RS12995	COG0301	tRNA thio-modification
QF06_RS13000	COG1104	cysteine desulfurase activity
QF06_RS13005	COG1114	Component of the transport system for branched-chain amino acids
QF06_RS13010	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
QF06_RS13015	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
QF06_RS13020	COG1309	transcriptional regulator
QF06_RS13025	COG1956	GAF domain-containing protein
QF06_RS13030	COG2203	Gaf domain
QF06_RS13030	COG2199	diguanylate cyclase activity
QF06_RS13035	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
QF06_RS13040	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
QF06_RS13045	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
QF06_RS13050	COG0454	-acetyltransferase
QF06_RS13055	COG0517	IMP dehydrogenase activity
QF06_RS13060	COG0123	including yeast histone deacetylase and acetoin utilization protein
QF06_RS13065	COG1360	Flagellar Motor Protein
QF06_RS13070	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
QF06_RS13075	COG1609	Transcriptional regulator
QF06_RS13080	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
QF06_RS13080	COG1605	Chorismate mutase
QF06_RS13085	COG3118	belongs to the thioredoxin family
QF06_RS13090	COG4980	gas vesicle protein
QF06_RS13095	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
QF06_RS13100	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
QF06_RS13105	COG1674	ftsk spoiiie
QF06_RS13110	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
QF06_RS13115	COG4848	Belongs to the UPF0354 family
QF06_RS13120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
QF06_RS13130	COG1363	Peptidase, m42
QF06_RS13135	COG5584	Small secreted protein
QF06_RS13140	COG0281	malic enzyme
QF06_RS13145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
QF06_RS13150	COG0220	tRNA (guanine-N7-)-methyltransferase activity
QF06_RS13160	COG0510	thiamine kinase activity
QF06_RS13165	COG1523	belongs to the glycosyl hydrolase 13 family
QF06_RS13170	COG1597	lipid kinase activity
QF06_RS13180	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
QF06_RS13185	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
QF06_RS13190	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
QF06_RS13195	COG2252	PERMEase
QF06_RS13200	COG4473	ABC transporter
QF06_RS13205	COG1131	(ABC) transporter
QF06_RS13210	COG1349	DNA-binding transcription factor activity
QF06_RS13215	COG1187	pseudouridine synthase activity
QF06_RS13220	COG2244	polysaccharide biosynthetic process
QF06_RS13225	COG2081	HI0933 family
QF06_RS13230	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
QF06_RS13240	COG5578	integral membrane protein
QF06_RS13245	COG0673	inositol 2-dehydrogenase activity
QF06_RS13250	COG1653	transport
QF06_RS13255	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
QF06_RS13260	COG4209	transmembrane transport
QF06_RS13265	COG2207	Transcriptional regulator
QF06_RS13270	COG1653	transport
QF06_RS13275	COG0395	ABC-type sugar transport system, permease component
QF06_RS13280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
QF06_RS13285	COG2124	cytochrome p450
QF06_RS13290	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
QF06_RS13300	COG0156	8-amino-7-oxononanoate synthase activity
QF06_RS13305	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
QF06_RS13315	COG1073	alpha beta
QF06_RS13320	COG1609	Transcriptional regulator
QF06_RS13325	COG1653	transport
QF06_RS13330	COG1175	transmembrane transport
QF06_RS13335	COG0395	ABC-type sugar transport system, permease component
QF06_RS13340	COG1486	melibiose metabolic process
QF06_RS13345	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
QF06_RS13350	COG0495	leucyl-tRNA aminoacylation
QF06_RS13360	COG2202	Pas domain
QF06_RS13360	COG1366	Belongs to the anti-sigma-factor antagonist family
QF06_RS13365	COG2814	Major facilitator Superfamily
QF06_RS13370	COG2433	Pfam Transposase IS66
QF06_RS13375	COG0577	efflux transmembrane transporter activity
QF06_RS13380	COG1136	(ABC) transporter
QF06_RS13385	COG2205	protein histidine kinase activity
QF06_RS13390	COG0745	RESPONSE REGULATOR receiver
QF06_RS13395	COG0577	efflux transmembrane transporter activity
QF06_RS13400	COG1136	(ABC) transporter
QF06_RS13415	COG1131	(ABC) transporter
QF06_RS13420	COG1725	Transcriptional regulator
QF06_RS13430	COG1242	4 iron, 4 sulfur cluster binding
QF06_RS13435	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
QF06_RS13445	COG2267	carboxylic ester hydrolase activity
QF06_RS13450	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
QF06_RS13455	COG1113	amino acid transport
QF06_RS13460	COG0367	asparagine synthase
QF06_RS13465	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
QF06_RS13470	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
QF06_RS13480	COG1506	peptidase
QF06_RS13485	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
QF06_RS13490	COG1116	anion transmembrane transporter activity
QF06_RS13495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
QF06_RS13500	COG0494	nUDIX hydrolase
QF06_RS13505	COG4824	toxin secretion phage lysis holin
QF06_RS13510	COG0783	Belongs to the Dps family
QF06_RS13525	COG1854	S-ribosylhomocysteine lyase activity
QF06_RS13530	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
QF06_RS13535	COG0288	reversible hydration of carbon dioxide
QF06_RS13540	COG0254	rRNA binding
QF06_RS13545	COG1271	oxidase subunit
QF06_RS13550	COG1294	oxidase, subunit
QF06_RS13555	COG1108	ABC-type Mn2 Zn2 transport systems permease components
QF06_RS13560	COG1321	iron dependent repressor
QF06_RS13560	COG1108	ABC-type Mn2 Zn2 transport systems permease components
QF06_RS13565	COG1121	(ABC) transporter
QF06_RS13570	COG0803	Belongs to the bacterial solute-binding protein 9 family
QF06_RS13575	COG4948	Mandelate Racemase Muconate Lactonizing
QF06_RS13580	COG0318	PFAM AMP-dependent synthetase and ligase
QF06_RS13585	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
QF06_RS13590	COG0596	Alpha beta hydrolase
QF06_RS13595	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
QF06_RS13600	COG1169	isochorismate synthase
QF06_RS13605	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
QF06_RS13610	COG1210	Utp--glucose-1-phosphate uridylyltransferase
QF06_RS13615	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
QF06_RS13620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
QF06_RS13625	COG0438	transferase activity, transferring glycosyl groups
QF06_RS13635	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
QF06_RS13640	COG0438	transferase activity, transferring glycosyl groups
QF06_RS13645	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
QF06_RS13650	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
QF06_RS13655	COG0058	SHG alpha-glucan phosphorylase activity
QF06_RS13660	COG0297	glycogen (starch) synthase activity
QF06_RS13665	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
QF06_RS13670	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
QF06_RS13675	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
QF06_RS13800	COG3859	Proton-coupled thiamine transporter YuaJ
QF06_RS13805	COG1247	-acetyltransferase
QF06_RS13810	COG2268	Band 7 protein
QF06_RS13815	COG1585	Membrane protein implicated in regulation of membrane protease activity
QF06_RS13820	COG2318	DinB family
QF06_RS13830	COG1454	alcohol dehydrogenase
QF06_RS13835	COG1012	belongs to the aldehyde dehydrogenase family
QF06_RS13840	COG1510	regulation of RNA biosynthetic process
QF06_RS13850	COG0569	domain protein
QF06_RS13855	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
QF06_RS13860	COG4682	membrane
QF06_RS13865	COG1705	Flagellar rod assembly protein muramidase FlgJ
QF06_RS13870	COG0477	Major facilitator Superfamily
QF06_RS13875	COG5553	Cysteine dioxygenase type I
QF06_RS13885	COG1968	undecaprenyl-diphosphatase activity
QF06_RS13890	COG0628	permease
QF06_RS13895	COG0673	inositol 2-dehydrogenase activity
QF06_RS13900	COG4806	L-rhamnose isomerase
QF06_RS13905	COG3254	rhamnose metabolic process
QF06_RS13910	COG1070	Carbohydrate kinase
QF06_RS13915	COG1349	DNA-binding transcription factor activity
QF06_RS13920	COG1028	Short-chain dehydrogenase reductase Sdr
QF06_RS13920	COG3347	Dehydrogenase
QF06_RS13925	COG0840	transmembrane signaling receptor activity
QF06_RS13930	COG0840	transmembrane signaling receptor activity
QF06_RS13935	COG0840	transmembrane signaling receptor activity
QF06_RS13940	COG0840	transmembrane signaling receptor activity
QF06_RS13955	COG0432	Pfam Uncharacterised protein family UPF0047
QF06_RS13960	COG0366	Alpha amylase catalytic
QF06_RS13965	COG1253	flavin adenine dinucleotide binding
QF06_RS13970	COG2738	Putative neutral zinc metallopeptidase
QF06_RS13985	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
QF06_RS14000	COG0166	Belongs to the GPI family
QF06_RS14005	COG1979	alcohol dehydrogenase
QF06_RS14010	COG1979	alcohol dehydrogenase
QF06_RS14015	COG2155	Conserved Protein
QF06_RS14020	COG1098	S1 RNA binding domain
QF06_RS14025	COG0436	Aminotransferase
QF06_RS14030	COG1522	sequence-specific DNA binding
QF06_RS14035	COG2267	carboxylic ester hydrolase activity
QF06_RS14045	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
QF06_RS14050	COG2205	protein histidine kinase activity
QF06_RS14060	COG5018	Exonuclease
QF06_RS14070	COG2814	Major facilitator Superfamily
QF06_RS14075	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
QF06_RS14080	COG3011	Protein conserved in bacteria
QF06_RS14090	COG3290	protein histidine kinase activity
QF06_RS14095	COG4565	transcriptional regulatory protein
QF06_RS14100	COG1744	ABC transporter substrate-binding protein PnrA-like
QF06_RS14105	COG3845	ABC transporter
QF06_RS14110	COG4603	Belongs to the binding-protein-dependent transport system permease family
QF06_RS14115	COG1079	Belongs to the binding-protein-dependent transport system permease family
QF06_RS14120	COG3493	citrate carrier protein
QF06_RS14130	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
QF06_RS14130	COG2111	Na H antiporter
QF06_RS14135	COG2111	Na H antiporter
QF06_RS14140	COG1006	Multisubunit Na H antiporter MnhC subunit
QF06_RS14145	COG0651	ATP synthesis coupled electron transport
QF06_RS14150	COG1863	multisubunit Na H antiporter MnhE subunit
QF06_RS14155	COG2212	antiporter activity
QF06_RS14160	COG1320	monovalent cation:proton antiporter activity
QF06_RS14165	COG2050	protein possibly involved in aromatic compounds catabolism
QF06_RS14170	COG2197	response regulator
QF06_RS14175	COG4585	Histidine kinase
QF06_RS14185	COG0142	geranyltranstransferase activity
QF06_RS14205	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
QF06_RS14210	COG1335	isochorismatase
QF06_RS14215	COG5506	Protein of unknown function (DUF1694)
QF06_RS14230	COG0628	permease
QF06_RS14245	COG1418	mRNA catabolic process
QF06_RS14250	COG1028	Short-chain dehydrogenase reductase Sdr
QF06_RS14260	COG1511	domain protein
QF06_RS14265	COG1674	ftsk spoiiie
QF06_RS14265	COG0433	COG0433 Predicted ATPase
QF06_RS14270	COG4499	WXG100 protein secretion system (Wss), protein YukC
QF06_RS14275	COG5417	Belongs to the EsaB family
QF06_RS14280	COG4842	Belongs to the WXG100 family
QF06_RS14285	COG2508	Transcriptional regulator
QF06_RS14285	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
QF06_RS14290	COG0686	Belongs to the AlaDH PNT family
QF06_RS14295	COG5634	Uncharacterized conserved protein (DUF2278)
QF06_RS14300	COG3251	PFAM MbtH domain protein
QF06_RS14305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
QF06_RS14310	COG1535	isochorismatase
QF06_RS14310	COG3433	isochorismatase activity
QF06_RS14315	COG1021	2,3-dihydroxybenzoate-AMP ligase
QF06_RS14320	COG1169	isochorismate synthase
QF06_RS14325	COG1028	Short-chain dehydrogenase reductase Sdr
QF06_RS14330	COG2819	hydrolase of the alpha beta superfamily
QF06_RS14335	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
QF06_RS14340	COG1268	BioY protein
QF06_RS14345	COG2056	Na+-H+ antiporter family
QF06_RS14350	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
QF06_RS14355	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
QF06_RS14360	COG3584	3D domain protein
QF06_RS14370	COG1252	NADH dehydrogenase
QF06_RS14375	COG0492	ferredoxin-NADP+ reductase activity
QF06_RS14380	COG0516	GMP reductase activity
QF06_RS14385	COG2808	Putative FMN-binding domain
QF06_RS14390	COG0456	acetyltransferase
QF06_RS14395	COG0316	Belongs to the HesB IscA family
QF06_RS14400	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
QF06_RS14405	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
QF06_RS14410	COG4844	belongs to the
QF06_RS14415	COG1252	NADH dehydrogenase
QF06_RS14420	COG4837	Protein of unknown function (DUF1462)
QF06_RS14425	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
QF06_RS14430	COG0823	Involved in the tonB-independent uptake of proteins
QF06_RS14430	COG1506	peptidase
QF06_RS14430	COG4946	Tricorn protease homolog
QF06_RS14435	COG0083	homoserine kinase activity
QF06_RS14440	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
QF06_RS14445	COG0460	homoserine dehydrogenase
QF06_RS14450	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
QF06_RS14455	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
QF06_RS14460	COG0647	UMP catabolic process
QF06_RS14465	COG2445	Protein of unknown function DUF86
QF06_RS14470	COG4470	Protein conserved in bacteria
QF06_RS14480	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
QF06_RS14485	COG0739	heme binding
QF06_RS14495	COG3377	Domain of unknown function (DUF1805)
QF06_RS14500	COG0737	Belongs to the 5'-nucleotidase family
QF06_RS14505	COG0730	response to heat
QF06_RS14510	COG1801	Protein of unknown function DUF72
QF06_RS14520	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
QF06_RS14525	COG2508	Transcriptional regulator
QF06_RS14530	COG2233	PERMEase
QF06_RS14535	COG2233	PERMEase
QF06_RS14540	COG3648	Uricase
QF06_RS14540	COG3195	allantoin biosynthetic process
QF06_RS14545	COG2351	hydroxyisourate hydrolase activity
QF06_RS14555	COG2080	2 iron, 2 sulfur cluster binding
QF06_RS14560	COG1529	Aldehyde oxidase and xanthine dehydrogenase
QF06_RS14565	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
QF06_RS14570	COG2068	MobA-Related Protein
QF06_RS14575	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
QF06_RS14580	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
QF06_RS14585	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
QF06_RS14590	COG2356	endonuclease I
QF06_RS14595	COG3842	ATPase activity
QF06_RS14600	COG2188	Transcriptional regulator
QF06_RS14605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
QF06_RS14610	COG0395	ABC-type sugar transport system, permease component
QF06_RS14615	COG1175	transmembrane transport
QF06_RS14620	COG1653	transport
QF06_RS14625	COG2222	sugar isomerase
QF06_RS14630	COG0322	excinuclease ABC activity
QF06_RS14635	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
QF06_RS14650	COG0346	lactoylglutathione lyase activity
QF06_RS14655	COG0640	Transcriptional regulator
QF06_RS14660	COG0719	Fe-S assembly protein
QF06_RS14665	COG0822	iron-sulfur transferase activity
QF06_RS14670	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
QF06_RS14675	COG0719	Fe-S assembly protein
QF06_RS14680	COG0396	ATPase activity
QF06_RS14685	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
QF06_RS14690	COG1464	Belongs to the NlpA lipoprotein family
QF06_RS14695	COG2011	ABC-type metal ion transport system permease component
QF06_RS14700	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
QF06_RS14710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
QF06_RS14715	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
QF06_RS14725	COG0509	glycine decarboxylation via glycine cleavage system
QF06_RS14730	COG1393	Belongs to the ArsC family
QF06_RS14735	COG1960	acyl-CoA dehydrogenase activity
QF06_RS14740	COG0183	Belongs to the thiolase family
QF06_RS14745	COG1024	Enoyl-CoA hydratase
QF06_RS14745	COG1250	3-hydroxyacyl-CoA dehydrogenase
QF06_RS14750	COG0506	proline dehydrogenase activity
QF06_RS14760	COG5577	PFAM Coat F domain
QF06_RS14765	COG1846	Transcriptional regulator
QF06_RS14770	COG0477	Major facilitator Superfamily
QF06_RS14775	COG1942	4-Oxalocrotonate Tautomerase
QF06_RS14780	COG1028	Short-chain dehydrogenase reductase Sdr
QF06_RS14785	COG1028	Short-chain dehydrogenase reductase Sdr
QF06_RS14790	COG0583	DNA-binding transcription factor activity
QF06_RS14800	COG1120	ATPase activity
QF06_RS14815	COG1028	Short-chain dehydrogenase reductase Sdr
QF06_RS14820	COG0783	Belongs to the Dps family
QF06_RS14825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
QF06_RS14830	COG0745	RESPONSE REGULATOR receiver
QF06_RS14835	COG2205	protein histidine kinase activity
QF06_RS14835	COG2770	Histidine kinase
QF06_RS14840	COG1309	transcriptional regulator
QF06_RS14845	COG0114	fumarate hydratase activity
QF06_RS14855	COG0697	spore germination
QF06_RS14860	COG0814	amino acid
QF06_RS14870	COG2197	response regulator
QF06_RS14875	COG4585	Histidine kinase
QF06_RS14880	COG4758	membrane
QF06_RS14885	COG3595	metallopeptidase activity
QF06_RS14890	COG1842	Phage shock protein A
QF06_RS14895	COG4758	membrane
QF06_RS14900	COG2814	Major facilitator Superfamily
QF06_RS14905	COG2096	Adenosyltransferase
QF06_RS14910	COG1120	ATPase activity
QF06_RS14915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
QF06_RS14920	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
QF06_RS14925	COG1028	Short-chain dehydrogenase reductase Sdr
QF06_RS14930	COG3386	PFAM SMP-30 Gluconolaconase
QF06_RS14935	COG2205	protein histidine kinase activity
QF06_RS14940	COG0745	RESPONSE REGULATOR receiver
QF06_RS14950	COG1191	sigma factor activity
QF06_RS14955	COG2140	Oxalate decarboxylase
QF06_RS14965	COG0577	efflux transmembrane transporter activity
QF06_RS14970	COG1136	(ABC) transporter
QF06_RS14975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
QF06_RS14980	COG1120	ATPase activity
QF06_RS14985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
QF06_RS14990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
QF06_RS14995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
QF06_RS15005	COG0531	amino acid
QF06_RS15015	COG1988	membrane-bound metal-dependent
QF06_RS15020	COG1368	sulfuric ester hydrolase activity
QF06_RS15025	COG1910	domain protein
QF06_RS15030	COG0725	ABC transporter, periplasmic molybdate-binding protein
QF06_RS15035	COG4149	molybdate abc transporter
QF06_RS15040	COG0656	L-ascorbic acid biosynthetic process
QF06_RS15050	COG0025	NhaP-type Na H and K H
QF06_RS15055	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
QF06_RS15060	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
QF06_RS15065	COG3973	AAA domain
QF06_RS15075	COG2860	membrane
QF06_RS15080	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
QF06_RS15085	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
QF06_RS15090	COG2217	Heavy metal translocating P-type atpase
QF06_RS15095	COG2217	Heavy metal translocating P-type atpase
QF06_RS15100	COG2608	mercury ion transmembrane transporter activity
QF06_RS15105	COG1937	Protein conserved in bacteria
QF06_RS15110	COG0673	inositol 2-dehydrogenase activity
QF06_RS15115	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
QF06_RS15120	COG1289	transmembrane transporter activity
QF06_RS15130	COG2076	Multidrug Resistance protein
QF06_RS15135	COG1309	transcriptional regulator
QF06_RS15140	COG1028	Short-chain dehydrogenase reductase Sdr
QF06_RS15155	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
QF06_RS15160	COG0557	exoribonuclease II activity
QF06_RS15165	COG1647	Serine aminopeptidase, S33
QF06_RS15170	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
QF06_RS15175	COG0596	Alpha beta hydrolase
QF06_RS15180	COG1476	TRANSCRIPTIONal
QF06_RS15185	COG1396	sequence-specific DNA binding
QF06_RS15190	COG1396	sequence-specific DNA binding
QF06_RS15195	COG1733	regulation of RNA biosynthetic process
QF06_RS15200	COG0840	transmembrane signaling receptor activity
QF06_RS15225	COG1131	(ABC) transporter
QF06_RS15255	COG1174	glycine betaine transport
QF06_RS15260	COG1732	Glycine betaine
QF06_RS15265	COG1174	glycine betaine transport
QF06_RS15270	COG1125	glycine betaine transport
QF06_RS15270	COG0517	IMP dehydrogenase activity
QF06_RS15275	COG1510	regulation of RNA biosynthetic process
QF06_RS15280	COG1174	glycine betaine transport
QF06_RS15285	COG1732	Glycine betaine
QF06_RS15290	COG1174	glycine betaine transport
QF06_RS15295	COG1125	glycine betaine transport
QF06_RS15295	COG0517	IMP dehydrogenase activity
QF06_RS15300	COG1510	regulation of RNA biosynthetic process
QF06_RS15305	COG2095	MarC family integral membrane protein
QF06_RS15315	COG3064	Membrane
QF06_RS15320	COG4640	response to antibiotic
QF06_RS15325	COG0456	acetyltransferase
QF06_RS15330	COG0148	phosphopyruvate hydratase activity
QF06_RS15335	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
QF06_RS15340	COG0149	triose-phosphate isomerase activity
QF06_RS15345	COG0126	phosphoglycerate kinase activity
QF06_RS15350	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
QF06_RS15355	COG2390	Transcriptional regulator
QF06_RS15360	COG2814	Major facilitator Superfamily
QF06_RS15365	COG1609	Transcriptional regulator
QF06_RS15370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
QF06_RS15375	COG0583	DNA-binding transcription factor activity
QF06_RS15380	COG0697	spore germination
QF06_RS15385	COG1113	amino acid transport
QF06_RS15390	COG3858	chitin binding
QF06_RS15395	COG1556	Lactate utilization protein
QF06_RS15400	COG1139	Iron-sulfur cluster binding protein
QF06_RS15405	COG0247	lactate metabolic process
QF06_RS15410	COG2197	response regulator
QF06_RS15415	COG4585	Histidine kinase
QF06_RS15420	COG0842	Transport permease protein
QF06_RS15425	COG1131	(ABC) transporter
QF06_RS15430	COG0596	Alpha beta hydrolase
QF06_RS15435	COG2208	phosphoserine phosphatase activity
QF06_RS15440	COG3867	Arabinogalactan endo-beta-1,4-galactanase
QF06_RS15445	COG1874	Beta-galactosidase
QF06_RS15450	COG3833	ABC-type maltose transport systems, permease component
QF06_RS15455	COG1175	transmembrane transport
QF06_RS15460	COG2182	Extracellular solute-binding protein
QF06_RS15465	COG1609	Transcriptional regulator
QF06_RS15470	COG2186	Transcriptional regulator
QF06_RS15475	COG1620	l-lactate permease
QF06_RS15480	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
QF06_RS15490	COG5039	Polysaccharide pyruvyl transferase
QF06_RS15495	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
QF06_RS15500	COG0110	maltose O-acetyltransferase activity
QF06_RS15505	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
QF06_RS15510	COG2244	polysaccharide biosynthetic process
QF06_RS15515	COG1216	Glycosyl transferase, family 2
QF06_RS15520	COG5039	Polysaccharide pyruvyl transferase
QF06_RS15525	COG1216	Glycosyl transferase, family 2
QF06_RS15535	COG0438	transferase activity, transferring glycosyl groups
QF06_RS15540	COG1215	transferase activity, transferring glycosyl groups
QF06_RS15545	COG0438	transferase activity, transferring glycosyl groups
QF06_RS15550	COG1086	Polysaccharide biosynthesis protein
QF06_RS15555	COG0489	protein tyrosine kinase activity
QF06_RS15560	COG3944	biosynthesis protein
QF06_RS15565	COG1396	sequence-specific DNA binding
QF06_RS15570	COG2272	Belongs to the type-B carboxylesterase lipase family
QF06_RS15580	COG3479	Phenolic acid decarboxylase
QF06_RS15590	COG1794	racemase activity, acting on amino acids and derivatives
QF06_RS15595	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
QF06_RS15600	COG1621	beta-fructofuranosidase activity
QF06_RS15605	COG1621	beta-fructofuranosidase activity
QF06_RS15610	COG0531	amino acid
QF06_RS15615	COG1309	transcriptional regulator
QF06_RS15620	COG2076	Multidrug Resistance protein
QF06_RS15625	COG2076	Multidrug Resistance protein
QF06_RS15640	COG0740	serine-type endopeptidase activity
QF06_RS15645	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
QF06_RS15650	COG0366	Alpha amylase catalytic
QF06_RS15655	COG1554	hydrolase, family 65, central catalytic
QF06_RS15660	COG5521	maltodextrose utilization protein MalA
QF06_RS15665	COG3833	ABC-type maltose transport systems, permease component
QF06_RS15670	COG1175	transmembrane transport
QF06_RS15675	COG2182	Extracellular solute-binding protein
QF06_RS15680	COG0366	Alpha amylase catalytic
QF06_RS15685	COG1609	Transcriptional regulator
QF06_RS15690	COG1611	Belongs to the LOG family
QF06_RS15695	COG1694	Mazg nucleotide pyrophosphohydrolase
QF06_RS15700	COG0659	secondary active sulfate transmembrane transporter activity
QF06_RS15705	COG0288	reversible hydration of carbon dioxide
QF06_RS15710	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
QF06_RS15715	COG0577	efflux transmembrane transporter activity
QF06_RS15720	COG1136	(ABC) transporter
QF06_RS15725	COG5002	protein histidine kinase activity
QF06_RS15730	COG0745	RESPONSE REGULATOR receiver
QF06_RS15745	COG2162	N-hydroxyarylamine O-acetyltransferase activity
QF06_RS15750	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
QF06_RS15755	COG1481	regulation of sporulation
QF06_RS15760	COG0391	Required for morphogenesis under gluconeogenic growth conditions
QF06_RS15765	COG1660	Displays ATPase and GTPase activities
QF06_RS15770	COG1051	belongs to the nudix hydrolase family
QF06_RS15775	COG0492	ferredoxin-NADP+ reductase activity
QF06_RS15780	COG0791	NLP P60 protein
QF06_RS15780	COG3883	PFAM NLP P60 protein
QF06_RS15785	COG0457	Tetratricopeptide repeat
QF06_RS15790	COG1132	(ABC) transporter
QF06_RS15810	COG0140	phosphoribosyl-ATP diphosphatase activity
QF06_RS15810	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
QF06_RS15815	COG0107	imidazoleglycerol-phosphate synthase activity
QF06_RS15820	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
QF06_RS15825	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
QF06_RS15830	COG0131	Imidazoleglycerol-phosphate dehydratase
QF06_RS15835	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
QF06_RS15840	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
QF06_RS15845	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
QF06_RS15850	COG4990	cell redox homeostasis
QF06_RS15855	COG5297	Belongs to the glycosyl hydrolase family 6
QF06_RS15860	COG0110	maltose O-acetyltransferase activity
QF06_RS15865	COG0546	phosphoglycolate phosphatase activity
QF06_RS15870	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
QF06_RS15875	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
QF06_RS15880	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
QF06_RS15885	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
QF06_RS15890	COG0363	glucosamine-6-phosphate deaminase activity
QF06_RS15895	COG2188	Transcriptional regulator
QF06_RS15900	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
QF06_RS15905	COG1846	Transcriptional regulator
QF06_RS15920	COG1846	Transcriptional regulator
QF06_RS15925	COG2814	Major facilitator Superfamily
QF06_RS15930	COG1950	PFAM Membrane protein of
QF06_RS15935	COG1983	PspC domain protein
QF06_RS15940	COG3595	metallopeptidase activity
QF06_RS15955	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
QF06_RS15960	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
QF06_RS15965	COG0556	nucleotide-excision repair
QF06_RS15970	COG4897	Protein conserved in bacteria
QF06_RS15975	COG0574	Belongs to the PEP-utilizing enzyme family
QF06_RS15975	COG3848	Pyruvate phosphate dikinase
QF06_RS15980	COG1309	transcriptional regulator
QF06_RS15985	COG2814	Major facilitator Superfamily
QF06_RS15990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
QF06_RS16000	COG0793	Belongs to the peptidase S41A family
QF06_RS16000	COG3409	Peptidoglycan-binding domain 1 protein
QF06_RS16005	COG2177	Part of the ABC transporter FtsEX involved in
QF06_RS16010	COG2884	Cell division ATP-binding protein ftsE
QF06_RS16015	COG2010	Cytochrome c
QF06_RS16020	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
QF06_RS16025	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
QF06_RS16030	COG0653	protein targeting
QF06_RS16035	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
QF06_RS16050	COG1516	flagellar protein fliS
QF06_RS16055	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
QF06_RS16060	COG1334	flagellar protein FlaG
QF06_RS16065	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
QF06_RS16070	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
QF06_RS16075	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
QF06_RS16085	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
QF06_RS16090	COG4786	Flagellar basal body rod
QF06_RS16090	COG1256	bacterial-type flagellum assembly
QF06_RS16095	COG3418	PFAM FlgN family protein
QF06_RS16100	COG2747	anti-sigma28 factor FlgM
QF06_RS16110	COG1040	competence protein
QF06_RS16120	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
QF06_RS16125	COG1307	EDD domain protein, DegV family
QF06_RS16130	COG2197	response regulator
QF06_RS16135	COG4585	Histidine kinase
QF06_RS16140	COG1739	Uncharacterized protein family UPF0029
QF06_RS16145	COG1316	TRANSCRIPTIONal
QF06_RS16150	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
QF06_RS16155	COG0438	transferase activity, transferring glycosyl groups
QF06_RS16160	COG1215	transferase activity, transferring glycosyl groups
QF06_RS16165	COG3206	protein involved in exopolysaccharide biosynthesis
QF06_RS16170	COG3307	-O-antigen
QF06_RS16175	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
QF06_RS16180	COG0438	transferase activity, transferring glycosyl groups
QF06_RS16180	COG0297	glycogen (starch) synthase activity
QF06_RS16185	COG2244	polysaccharide biosynthetic process
QF06_RS16200	COG2247	cell wall binding repeat
QF06_RS16200	COG0860	N-Acetylmuramoyl-L-alanine amidase
QF06_RS16205	COG2247	cell wall binding repeat
QF06_RS16205	COG2385	sporulation resulting in formation of a cellular spore
QF06_RS16215	COG1316	TRANSCRIPTIONal
QF06_RS16220	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
QF06_RS16240	COG1210	Utp--glucose-1-phosphate uridylyltransferase
QF06_RS16245	COG1134	teichoic acid transport
QF06_RS16250	COG1682	transport, permease protein
QF06_RS16255	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
QF06_RS16255	COG1215	transferase activity, transferring glycosyl groups
QF06_RS16260	COG0463	Glycosyl transferase, family 2
QF06_RS16305	COG4193	domain, Protein
QF06_RS16310	COG1482	cell wall glycoprotein biosynthetic process
QF06_RS16315	COG0697	spore germination
QF06_RS16320	COG0814	amino acid
QF06_RS16330	COG2814	Major facilitator Superfamily
QF06_RS16335	COG1316	TRANSCRIPTIONal
QF06_RS16340	COG0561	phosphatase activity
QF06_RS16345	COG0791	NLP P60 protein
QF06_RS16350	COG2843	Capsule synthesis protein
QF06_RS16360	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
QF06_RS16365	COG1609	Transcriptional regulator
QF06_RS16370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
QF06_RS16375	COG1869	D-ribose catabolic process
QF06_RS16380	COG1129	ABC transporter
QF06_RS16385	COG1172	Belongs to the binding-protein-dependent transport system permease family
QF06_RS16390	COG1879	ABC-type sugar transport system periplasmic component
QF06_RS16395	COG3103	Sh3 type 3 domain protein
QF06_RS16405	COG2249	NAD(P)H dehydrogenase (quinone) activity
QF06_RS16410	COG3527	Alpha-acetolactate decarboxylase
QF06_RS16415	COG0028	Belongs to the TPP enzyme family
QF06_RS16420	COG0583	DNA-binding transcription factor activity
QF06_RS16425	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
QF06_RS16440	COG5337	Spore coat protein CotH
QF06_RS16450	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
QF06_RS16460	COG0405	Gamma-glutamyltransferase
QF06_RS16465	COG1522	sequence-specific DNA binding
QF06_RS16470	COG2059	Chromate
QF06_RS16475	COG2059	Chromate
QF06_RS16490	COG5444	nuclease activity
QF06_RS16505	COG3878	Protein conserved in bacteria
QF06_RS16510	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
QF06_RS16515	COG4464	protein tyrosine phosphatase activity
QF06_RS16520	COG0489	protein tyrosine kinase activity
QF06_RS16525	COG3944	biosynthesis protein
QF06_RS16530	COG4715	Zinc finger, swim domain protein
QF06_RS16535	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
QF06_RS16540	COG0561	phosphatase activity
QF06_RS16545	COG1349	DNA-binding transcription factor activity
QF06_RS16550	COG0629	single-stranded DNA binding
QF06_RS16565	COG3764	Sortase (surface protein transpeptidase)
QF06_RS16575	COG3279	Response regulator of the LytR AlgR family
QF06_RS16580	COG0745	RESPONSE REGULATOR receiver
QF06_RS16580	COG2972	Histidine kinase
QF06_RS16585	COG1970	mechanosensitive ion channel activity
QF06_RS16590	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
QF06_RS16595	COG0457	Tetratricopeptide repeat
QF06_RS16600	COG4786	Flagellar basal body rod
QF06_RS16605	COG4786	Flagellar basal body rod
QF06_RS16610	COG1077	Cell shape determining protein MreB Mrl
QF06_RS16615	COG1609	Transcriptional regulator
QF06_RS16620	COG1846	Transcriptional regulator
QF06_RS16625	COG2814	Major facilitator Superfamily
QF06_RS16630	COG3420	alginic acid biosynthetic process
QF06_RS16635	COG1953	Uracil, thiamine, allantoin
QF06_RS16640	COG0477	Major facilitator Superfamily
QF06_RS16645	COG1335	isochorismatase
QF06_RS16655	COG0004	ammonium transporteR
QF06_RS16660	COG0347	Belongs to the P(II) protein family
QF06_RS16665	COG0671	phosphoesterase, PA-phosphatase related
QF06_RS16675	COG0739	heme binding
QF06_RS16680	COG1247	-acetyltransferase
QF06_RS16695	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
QF06_RS16700	COG0789	Transcriptional regulator
QF06_RS16710	COG2910	NAD(P)H-binding
QF06_RS16715	COG1959	2 iron, 2 sulfur cluster binding
QF06_RS16720	COG0804	urea catabolic process
QF06_RS16725	COG0832	Belongs to the urease beta subunit family
QF06_RS16730	COG0831	urea catabolic process
QF06_RS16740	COG3237	CsbD-like
QF06_RS16745	COG1994	Peptidase M50
QF06_RS16750	COG0457	Tetratricopeptide repeat
QF06_RS16755	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
QF06_RS16760	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
QF06_RS16765	COG2304	oxidoreductase activity
QF06_RS16775	COG2304	oxidoreductase activity
QF06_RS16780	COG2385	sporulation resulting in formation of a cellular spore
QF06_RS16785	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
QF06_RS16795	COG4836	Membrane
QF06_RS16805	COG0355	proton-transporting ATP synthase activity, rotational mechanism
QF06_RS16810	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
QF06_RS16815	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
QF06_RS16820	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
QF06_RS16825	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
QF06_RS16830	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
QF06_RS16840	COG0356	it plays a direct role in the translocation of protons across the membrane
QF06_RS16850	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
QF06_RS16855	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
QF06_RS16860	COG4475	Protein of unknown function (DUF436)
QF06_RS16865	COG0698	ribose 5-phosphate isomerase
QF06_RS16870	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
QF06_RS16875	COG1971	Probably functions as a manganese efflux pump
QF06_RS16880	COG0009	L-threonylcarbamoyladenylate synthase
QF06_RS16885	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
QF06_RS16905	COG2890	protein-(glutamine-N5) methyltransferase activity
QF06_RS16910	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
QF06_RS16915	COG0346	lactoylglutathione lyase activity
QF06_RS16920	COG0789	Transcriptional regulator
QF06_RS16925	COG0679	Auxin Efflux Carrier
QF06_RS16930	COG0281	malic enzyme
QF06_RS16935	COG1435	thymidine kinase activity
QF06_RS16945	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
QF06_RS16950	COG1494	fructose-1,6-bisphosphatase
QF06_RS16955	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
QF06_RS16960	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
QF06_RS16965	COG0191	fructose-bisphosphate aldolase activity
QF06_RS16970	COG2204	response regulator
QF06_RS16975	COG4821	SIS domain
QF06_RS16980	COG0504	CTP synthase activity
QF06_RS16985	COG3343	RNA polymerase activity
QF06_RS16990	COG1960	acyl-CoA dehydrogenase activity
QF06_RS16995	COG0247	lactate metabolic process
QF06_RS16995	COG2181	nitrate reductase activity
QF06_RS17000	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
QF06_RS17005	COG4294	response to UV
QF06_RS17015	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
QF06_RS17020	COG1132	(ABC) transporter
QF06_RS17025	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
QF06_RS17030	COG2181	nitrate reductase activity
QF06_RS17035	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
QF06_RS17040	COG1140	nitrate reductase beta subunit
QF06_RS17045	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
QF06_RS17050	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
QF06_RS17060	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
QF06_RS17065	COG2223	nitrite transmembrane transporter activity
QF06_RS17070	COG0018	arginyl-trna synthetase
QF06_RS17075	COG4506	Protein conserved in bacteria
QF06_RS17085	COG0535	radical SAM domain protein
QF06_RS17095	COG1131	(ABC) transporter
QF06_RS17100	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
QF06_RS17105	COG0612	Peptidase, M16
QF06_RS17110	COG0612	Peptidase, M16
QF06_RS17120	COG3391	amine dehydrogenase activity
QF06_RS17125	COG3391	amine dehydrogenase activity
QF06_RS17135	COG0457	Tetratricopeptide repeat
QF06_RS17165	COG1131	(ABC) transporter
QF06_RS17175	COG0010	Belongs to the arginase family
QF06_RS17180	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
QF06_RS17185	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
QF06_RS17200	COG1994	Peptidase M50
QF06_RS17205	COG1942	4-Oxalocrotonate Tautomerase
QF06_RS17210	COG1846	Transcriptional regulator
QF06_RS17215	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
QF06_RS17220	COG0477	Major facilitator Superfamily
QF06_RS17225	COG1959	2 iron, 2 sulfur cluster binding
QF06_RS17230	COG3465	dGTPase activity
QF06_RS17235	COG1078	dGTPase activity
QF06_RS17240	COG4844	belongs to the
QF06_RS17250	COG0697	spore germination
QF06_RS17255	COG0095	Lipoate-protein ligase
QF06_RS17260	COG0583	DNA-binding transcription factor activity
QF06_RS17265	COG0280	phosphate acetyltransferase
QF06_RS17270	COG3253	May function as heme-dependent peroxidase
QF06_RS17275	COG1028	Short-chain dehydrogenase reductase Sdr
QF06_RS17280	COG0436	Aminotransferase
QF06_RS17285	COG2814	Major facilitator Superfamily
QF06_RS17290	COG0151	Belongs to the GarS family
QF06_RS17295	COG1028	Short-chain dehydrogenase reductase Sdr
QF06_RS17300	COG1917	Cupin 2, conserved barrel domain protein
QF06_RS17305	COG0077	Prephenate dehydratase
QF06_RS17310	COG2814	Major facilitator Superfamily
QF06_RS17315	COG0833	amino acid
QF06_RS17320	COG4187	Peptidase family M20/M25/M40
QF06_RS17325	COG1012	belongs to the aldehyde dehydrogenase family
QF06_RS17330	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
QF06_RS17340	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
QF06_RS17345	COG1091	dTDP-4-dehydrorhamnose reductase activity
QF06_RS17350	COG1088	dTDP-glucose 4,6-dehydratase activity
QF06_RS17355	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
QF06_RS17360	COG3980	spore coat polysaccharide biosynthesis protein
QF06_RS17365	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
QF06_RS17370	COG2089	acid synthase
QF06_RS17375	COG0456	acetyltransferase
QF06_RS17380	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
QF06_RS17385	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
QF06_RS17390	COG0463	Glycosyl transferase, family 2
QF06_RS17400	COG2363	Small membrane protein
QF06_RS17405	COG2233	PERMEase
QF06_RS17415	COG1012	belongs to the aldehyde dehydrogenase family
QF06_RS17420	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
QF06_RS17425	COG1216	Glycosyl transferase, family 2
QF06_RS17440	COG1695	Transcriptional regulator
QF06_RS17445	COG0351	phosphomethylpyrimidine kinase
QF06_RS17455	COG1621	beta-fructofuranosidase activity
QF06_RS17460	COG1263	PTS System
QF06_RS17460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
QF06_RS17465	COG2116	formate transmembrane transporter activity
QF06_RS17470	COG3711	transcriptional antiterminator
QF06_RS17480	COG1404	Belongs to the peptidase S8 family
QF06_RS17485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
QF06_RS17490	COG0778	Nitroreductase
QF06_RS17495	COG0772	Belongs to the SEDS family
QF06_RS17505	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
QF06_RS17510	COG1845	cytochrome c oxidase, subunit III
QF06_RS17515	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
QF06_RS17520	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
QF06_RS17525	COG2261	transglycosylase associated protein
QF06_RS17530	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
QF06_RS17535	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
QF06_RS17540	COG2246	polysaccharide biosynthetic process
QF06_RS17545	COG1309	transcriptional regulator
QF06_RS17555	COG3162	membrane
QF06_RS17560	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
QF06_RS17565	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
QF06_RS17570	COG2837	iron assimilation
QF06_RS17575	COG2822	iron ion transport
QF06_RS17580	COG0672	)-iron permease
QF06_RS17585	COG0352	thiamine-phosphate diphosphorylase activity
QF06_RS17590	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
QF06_RS17595	COG0583	DNA-binding transcription factor activity
QF06_RS17600	COG1380	Effector of murein hydrolase LrgA
QF06_RS17605	COG1346	cytolysis
QF06_RS17610	COG2814	Major facilitator Superfamily
QF06_RS17615	COG4895	conserved protein (DUF2196)
QF06_RS17620	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
QF06_RS17625	COG0346	lactoylglutathione lyase activity
QF06_RS17640	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
QF06_RS17645	COG1404	Belongs to the peptidase S8 family
QF06_RS17650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
QF06_RS17650	COG1263	PTS System
QF06_RS17655	COG3711	transcriptional antiterminator
QF06_RS17660	COG1442	glycosyl transferase family 8
QF06_RS17665	COG5522	Integral membrane protein (intg_mem_TP0381)
QF06_RS17670	COG1846	Transcriptional regulator
QF06_RS17675	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
QF06_RS17680	COG2234	aminopeptidase activity
QF06_RS17695	COG2814	Major facilitator Superfamily
QF06_RS17700	COG2357	RelA SpoT domain protein
QF06_RS17705	COG1575	Belongs to the MenA family. Type 1 subfamily
QF06_RS17715	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
QF06_RS17720	COG1696	Membrane protein involved in D-alanine export
QF06_RS17725	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
QF06_RS17730	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
QF06_RS17735	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
QF06_RS17740	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
QF06_RS17745	COG1486	melibiose metabolic process
QF06_RS17750	COG1447	Phosphotransferase system cellobiose-specific component IIA
QF06_RS17755	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
QF06_RS17760	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
QF06_RS17765	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
QF06_RS17765	COG3711	transcriptional antiterminator
QF06_RS17770	COG2094	Belongs to the DNA glycosylase MPG family
QF06_RS17775	COG0753	catalase activity
QF06_RS17780	COG2814	Major facilitator Superfamily
QF06_RS17785	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
QF06_RS17790	COG1131	(ABC) transporter
QF06_RS17810	COG1595	DNA-templated transcription, initiation
QF06_RS17815	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
QF06_RS17820	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
QF06_RS17825	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
QF06_RS17830	COG4988	ABC transporter
QF06_RS17835	COG1294	oxidase, subunit
QF06_RS17840	COG1271	oxidase subunit
QF06_RS17845	COG3493	citrate carrier protein
QF06_RS17850	COG0501	Belongs to the peptidase M48B family
QF06_RS17860	COG0726	polysaccharide deacetylase
QF06_RS17875	COG3842	ATPase activity
QF06_RS17880	COG2508	Transcriptional regulator
QF06_RS17885	COG1012	belongs to the aldehyde dehydrogenase family
QF06_RS17890	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
QF06_RS17900	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
QF06_RS17905	COG1881	PFAM PEBP family protein
QF06_RS17910	COG0583	DNA-binding transcription factor activity
QF06_RS17920	COG4585	Histidine kinase
QF06_RS17925	COG2197	response regulator
QF06_RS17930	COG2195	Cleaves the N-terminal amino acid of tripeptides
QF06_RS17935	COG4894	glucomannan catabolic process
QF06_RS17940	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
QF06_RS17945	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
QF06_RS17950	COG1028	Short-chain dehydrogenase reductase Sdr
QF06_RS17955	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
QF06_RS17960	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
QF06_RS17965	COG2610	gluconate transmembrane transporter activity
QF06_RS17970	COG0500	methyltransferase
QF06_RS17975	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
QF06_RS17990	COG0693	protein deglycase activity
QF06_RS17990	COG0753	catalase activity
QF06_RS17995	COG2851	Citrate transporter
QF06_RS18000	COG2273	Hydrolase Family 16
QF06_RS18005	COG3711	transcriptional antiterminator
QF06_RS18015	COG2270	Major facilitator Superfamily
QF06_RS18020	COG0513	Belongs to the DEAD box helicase family
QF06_RS18025	COG2755	lipolytic protein G-D-S-L family
QF06_RS18025	COG3401	FG-GAP repeat protein
QF06_RS18065	COG3209	COG3209 Rhs family protein
QF06_RS18070	COG0697	spore germination
QF06_RS18075	COG0589	response to stress
QF06_RS18080	COG2723	6-phospho-beta-galactosidase activity
QF06_RS18085	COG1263	PTS System
QF06_RS18085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
QF06_RS18085	COG2190	(PTS) system
QF06_RS18095	COG5444	nuclease activity
QF06_RS18115	COG5444	nuclease activity
QF06_RS18130	COG3507	Belongs to the glycosyl hydrolase 43 family
QF06_RS18140	COG2986	histidine ammonia-lyase
QF06_RS18145	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
QF06_RS18150	COG1228	amidohydrolase
QF06_RS18155	COG0010	Belongs to the arginase family
QF06_RS18160	COG0833	amino acid
QF06_RS18165	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
QF06_RS18170	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
QF06_RS18175	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
QF06_RS18180	COG2390	Transcriptional regulator
QF06_RS18190	COG3192	ethanolamine utilization protein
QF06_RS18195	COG2079	MmgE PrpD family protein
QF06_RS18200	COG1473	amidohydrolase
QF06_RS18205	COG1126	abc transporter atp-binding protein
QF06_RS18210	COG0765	amino acid transport
QF06_RS18215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
QF06_RS18220	COG0456	acetyltransferase
QF06_RS18225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
QF06_RS18230	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
QF06_RS18235	COG0561	phosphatase activity
QF06_RS18265	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
QF06_RS18270	COG5294	Protein conserved in bacteria
QF06_RS18275	COG0577	efflux transmembrane transporter activity
QF06_RS18280	COG1136	(ABC) transporter
QF06_RS18285	COG2205	protein histidine kinase activity
QF06_RS18290	COG0745	RESPONSE REGULATOR receiver
QF06_RS18295	COG0191	fructose-bisphosphate aldolase activity
QF06_RS18300	COG1082	Xylose isomerase domain protein TIM barrel
QF06_RS18305	COG1082	Xylose isomerase domain protein TIM barrel
QF06_RS18310	COG0673	inositol 2-dehydrogenase activity
QF06_RS18315	COG2814	Major facilitator Superfamily
QF06_RS18320	COG1082	Xylose isomerase domain protein TIM barrel
QF06_RS18325	COG3962	Belongs to the TPP enzyme family
QF06_RS18330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
QF06_RS18340	COG1012	belongs to the aldehyde dehydrogenase family
QF06_RS18345	COG1349	DNA-binding transcription factor activity
QF06_RS18350	COG0667	Aldo Keto reductase
QF06_RS18365	COG2814	Major facilitator Superfamily
QF06_RS18370	COG0326	Molecular chaperone. Has ATPase activity
QF06_RS18380	COG1028	Short-chain dehydrogenase reductase Sdr
QF06_RS18405	COG1309	transcriptional regulator
QF06_RS18410	COG1012	belongs to the aldehyde dehydrogenase family
QF06_RS18415	COG1714	RDD family
QF06_RS18420	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
QF06_RS18430	COG1714	RDD family
QF06_RS18435	COG2311	Membrane
QF06_RS18440	COG1917	Cupin 2, conserved barrel domain protein
QF06_RS18445	COG1309	transcriptional regulator
QF06_RS18450	COG1028	Short-chain dehydrogenase reductase Sdr
QF06_RS18455	COG1846	Transcriptional regulator
QF06_RS18460	COG1380	Effector of murein hydrolase LrgA
QF06_RS18465	COG1346	cytolysis
QF06_RS18470	COG5039	Polysaccharide pyruvyl transferase
QF06_RS18475	COG1929	Belongs to the glycerate kinase type-1 family
QF06_RS18480	COG1802	Transcriptional regulator
QF06_RS18485	COG1070	Carbohydrate kinase
QF06_RS18490	COG2610	gluconate transmembrane transporter activity
QF06_RS18495	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
QF06_RS18500	COG0450	alkyl hydroperoxide reductase
QF06_RS18505	COG3634	alkyl hydroperoxide reductase activity
QF06_RS18525	COG2188	Transcriptional regulator
QF06_RS18540	COG1131	(ABC) transporter
QF06_RS18545	COG1994	Peptidase M50
QF06_RS18550	COG0535	radical SAM domain protein
QF06_RS18560	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
QF06_RS18570	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
QF06_RS18580	COG1063	alcohol dehydrogenase
QF06_RS18600	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
QF06_RS18605	COG0456	acetyltransferase
QF06_RS18610	COG0457	Tetratricopeptide repeat
QF06_RS18620	COG0010	Belongs to the arginase family
QF06_RS18625	COG0833	amino acid
QF06_RS18630	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
QF06_RS18635	COG3829	transcription factor binding
QF06_RS18640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
QF06_RS18645	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
QF06_RS18650	COG4853	Protein conserved in bacteria
QF06_RS18655	COG4863	YycH protein
QF06_RS18660	COG5002	protein histidine kinase activity
QF06_RS18665	COG0745	RESPONSE REGULATOR receiver
QF06_RS18695	COG0346	lactoylglutathione lyase activity
QF06_RS18700	COG0305	Participates in initiation and elongation during chromosome replication
QF06_RS18715	COG2807	transmembrane transport
QF06_RS18720	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
QF06_RS18725	COG0359	binds to the 23S rRNA
QF06_RS18730	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
QF06_RS18735	COG4241	membrane
QF06_RS18745	COG5577	PFAM Coat F domain
QF06_RS18750	COG1733	regulation of RNA biosynthetic process
QF06_RS18755	COG1227	inorganic diphosphatase activity
QF06_RS18770	COG2271	Major facilitator Superfamily
QF06_RS18775	COG4978	Transcriptional regulator
QF06_RS18775	COG0789	Transcriptional regulator
QF06_RS18790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
QF06_RS18795	COG1846	Transcriptional regulator
QF06_RS18800	COG2153	protein acetylation
QF06_RS18805	COG2364	Membrane
QF06_RS18810	COG0456	acetyltransferase
QF06_RS18815	COG2315	Protein conserved in bacteria
QF06_RS18820	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
QF06_RS18830	COG0789	Transcriptional regulator
QF06_RS18835	COG0697	spore germination
QF06_RS18840	COG1331	Highly conserved protein containing a thioredoxin domain
QF06_RS18845	COG1266	CAAX protease self-immunity
QF06_RS18850	COG2814	Major facilitator Superfamily
QF06_RS18850	COG0477	Major facilitator Superfamily
QF06_RS18855	COG0110	maltose O-acetyltransferase activity
QF06_RS18860	COG0346	lactoylglutathione lyase activity
QF06_RS18865	COG1609	Transcriptional regulator
QF06_RS18870	COG0708	Exodeoxyribonuclease III
QF06_RS18875	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
QF06_RS18880	COG0629	single-stranded DNA binding
QF06_RS18885	COG0360	Binds together with S18 to 16S ribosomal RNA
QF06_RS18890	COG0012	GTP binding
QF06_RS18895	COG0243	molybdopterin cofactor binding
QF06_RS18900	COG4481	Protein conserved in bacteria
QF06_RS18905	COG3949	Membrane
QF06_RS18915	COG1475	DNA binding
QF06_RS18920	COG1192	Involved in chromosome partitioning
QF06_RS18930	COG1475	DNA binding
QF06_RS18935	COG0357	Ribosomal RNA small subunit methyltransferase G
QF06_RS18940	COG0445	tRNA wobble uridine modification
QF06_RS18945	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
QF06_RS18950	COG1847	R3H domain protein
QF06_RS18955	COG0706	membrane insertase activity
QF06_RS18960	COG0594	ribonuclease P activity
QF06_RS18970	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
QF06_RS18975	COG0592	DNA-directed DNA polymerase activity
QF06_RS18980	COG2501	S4 domain
QF06_RS18985	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
QF06_RS18995	COG0187	DNA topoisomerase II activity
QF06_RS19000	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
QF06_RS19025	COG0517	IMP dehydrogenase activity
QF06_RS19025	COG0516	GMP reductase activity
QF06_RS19030	COG1686	Belongs to the peptidase S11 family
QF06_RS19035	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
QF06_RS19040	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
QF06_RS19045	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
QF06_RS19055	COG1428	Deoxynucleoside kinase
QF06_RS19060	COG1428	Deoxynucleoside kinase
QF06_RS19065	COG1388	LysM domain
QF06_RS19065	COG3858	chitin binding
QF06_RS19070	COG1335	isochorismatase
QF06_RS19075	COG0590	tRNA wobble adenosine to inosine editing
QF06_RS19080	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
QF06_RS19085	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
QF06_RS19090	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
QF06_RS19125	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
QF06_RS19130	COG3853	Toxic anion resistance protein (TelA)
QF06_RS19135	COG1982	Orn Lys Arg decarboxylase major
QF06_RS19140	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
QF06_RS19145	COG3870	Protein conserved in bacteria
QF06_RS19150	COG1728	Protein conserved in bacteria
QF06_RS19155	COG0470	DNA polymerase III
QF06_RS19160	COG1774	PSP1 C-terminal conserved region
QF06_RS19165	COG4467	Involved in initiation control of chromosome replication
QF06_RS19170	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
QF06_RS19175	COG2827	Endonuclease containing a URI domain
QF06_RS19180	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
QF06_RS19185	COG2002	toxin-antitoxin pair type II binding
QF06_RS19190	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
QF06_RS19190	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
QF06_RS19195	COG0084	hydrolase, TatD family'
QF06_RS19200	COG3584	3D domain protein
QF06_RS19200	COG3583	domain protein
QF06_RS19205	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
QF06_RS19210	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
QF06_RS19220	COG4466	Protein conserved in bacteria
QF06_RS19230	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
QF06_RS19235	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
QF06_RS19240	COG0251	oxidation-reduction process
QF06_RS19245	COG2088	sporulation resulting in formation of a cellular spore
QF06_RS19250	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
QF06_RS19255	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
QF06_RS19260	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
QF06_RS19265	COG0193	aminoacyl-tRNA hydrolase activity
QF06_RS19275	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
QF06_RS19280	COG2002	toxin-antitoxin pair type II binding
QF06_RS19285	COG2244	polysaccharide biosynthetic process
QF06_RS19290	COG3956	TIGRFAM MazG family protein
QF06_RS19295	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
QF06_RS19310	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
QF06_RS19315	COG1098	S1 RNA binding domain
QF06_RS19330	COG2208	phosphoserine phosphatase activity
QF06_RS19335	COG2304	oxidoreductase activity
QF06_RS19340	COG0515	serine threonine protein kinase
QF06_RS19345	COG0037	tRNA processing
QF06_RS19350	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
QF06_RS19355	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
QF06_RS19360	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
QF06_RS19365	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
QF06_RS19370	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
QF06_RS19375	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
QF06_RS19380	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
QF06_RS19385	COG0512	Glutamine amidotransferase of anthranilate synthase
QF06_RS19390	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
QF06_RS19395	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
QF06_RS19400	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
QF06_RS19405	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
QF06_RS19410	COG1396	sequence-specific DNA binding
QF06_RS19415	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
QF06_RS19420	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
QF06_RS19485	COG4463	regulation of RNA biosynthetic process
QF06_RS19490	COG3880	PFAM UvrB UvrC protein
QF06_RS19495	COG3869	Catalyzes the specific phosphorylation of arginine residues in
QF06_RS19500	COG0542	response to heat
QF06_RS19505	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
QF06_RS19510	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
QF06_RS19515	COG4956	integral membrane protein (PIN domain superfamily)
QF06_RS19520	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
QF06_RS19525	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
QF06_RS19530	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
QF06_RS19540	COG1045	serine acetyltransferase
QF06_RS19545	COG0215	cysteine-tRNA ligase activity
QF06_RS19550	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
QF06_RS19555	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
QF06_RS19560	COG3688	RNA-binding protein containing a PIN domain
QF06_RS19565	COG1595	DNA-templated transcription, initiation
QF06_RS19570	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
QF06_RS19575	COG0250	Participates in transcription elongation, termination and antitermination
QF06_RS19585	COG0081	regulation of translation
QF06_RS19590	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
QF06_RS19600	COG2813	Specifically methylates the guanine in position
QF06_RS19605	COG0085	RNA polymerase activity
QF06_RS19610	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
QF06_RS19615	COG1358	cellular component organization or biogenesis
QF06_RS19620	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
QF06_RS19625	COG0049	tRNA binding
QF06_RS19630	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
QF06_RS19635	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
QF06_RS19640	COG0596	Alpha beta hydrolase
QF06_RS19650	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
QF06_RS19655	COG0088	Forms part of the polypeptide exit tunnel
QF06_RS19665	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
QF06_RS19680	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
QF06_RS19685	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
QF06_RS19695	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
QF06_RS19700	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
QF06_RS19710	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
QF06_RS19720	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
QF06_RS19725	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
QF06_RS19730	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
QF06_RS19735	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
QF06_RS19745	COG0200	Binds to the 23S rRNA
QF06_RS19750	COG0201	protein transport
QF06_RS19755	COG0563	adenylate kinase activity
QF06_RS19760	COG0024	Methionine aminopeptidase
QF06_RS19765	COG2163	COG2163 Ribosomal protein L14E L6E L27E
QF06_RS19775	COG0257	Belongs to the bacterial ribosomal protein bL36 family
QF06_RS19780	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
QF06_RS19785	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
QF06_RS19790	COG0202	RNA polymerase activity
QF06_RS19795	COG0203	ribosomal protein L17
QF06_RS19800	COG1122	ATPase activity
QF06_RS19805	COG1122	ATPase activity
QF06_RS19810	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
QF06_RS19815	COG0101	tRNA pseudouridine synthase activity
QF06_RS19820	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
QF06_RS19825	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
QF06_RS19830	COG2226	methyltransferase
QF06_RS19840	COG0860	N-Acetylmuramoyl-L-alanine amidase
QF06_RS19845	COG0489	protein tyrosine kinase activity
QF06_RS19855	COG2194	sulfuric ester hydrolase activity
QF06_RS19860	COG0726	polysaccharide deacetylase
QF06_RS19970	COG0659	secondary active sulfate transmembrane transporter activity
QF06_RS19975	COG0385	Bile acid
QF06_RS19980	COG2819	hydrolase of the alpha beta superfamily
QF06_RS19985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
QF06_RS19990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
QF06_RS19995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
QF06_RS20000	COG2207	Transcriptional regulator
QF06_RS20000	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
QF06_RS20005	COG3876	Protein conserved in bacteria
QF06_RS20010	COG1472	Belongs to the glycosyl hydrolase 3 family
QF06_RS20015	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
QF06_RS20020	COG1263	PTS System
QF06_RS20020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
QF06_RS20025	COG1737	Transcriptional regulator
QF06_RS20030	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
QF06_RS20035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
QF06_RS20040	COG1683	Conserved Protein
QF06_RS20070	COG1595	DNA-templated transcription, initiation
QF06_RS20075	COG5662	AntiSigma factor
QF06_RS20080	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
QF06_RS20085	COG4856	YbbR-like protein
QF06_RS20090	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
QF06_RS20095	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
QF06_RS20100	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
QF06_RS20105	COG2169	Transcriptional regulator
QF06_RS20110	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
QF06_RS20115	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
QF06_RS20120	COG3002	Belongs to the UPF0753 family
QF06_RS20125	COG0288	reversible hydration of carbon dioxide
QF06_RS20135	COG5609	conserved protein (DUF2294)
QF06_RS20140	COG0640	Transcriptional regulator
QF06_RS20145	COG2814	Major facilitator Superfamily
QF06_RS20160	COG0515	serine threonine protein kinase
QF06_RS20175	COG1113	amino acid transport
QF06_RS20190	COG2602	Beta-lactamase
QF06_RS20220	COG0531	amino acid
QF06_RS20260	COG3409	Peptidoglycan-binding domain 1 protein
QF06_RS20270	COG3409	Peptidoglycan-binding domain 1 protein
QF06_RS20460	COG4948	Mandelate Racemase Muconate Lactonizing
QF06_RS20465	COG4948	Mandelate Racemase Muconate Lactonizing
QF06_RS20480	COG2721	sulfolactate sulfo-lyase activity
QF06_RS20510	COG1131	(ABC) transporter
QF06_RS20645	COG0457	Tetratricopeptide repeat
QF06_RS20650	COG0457	Tetratricopeptide repeat
QF06_RS20710	COG1263	PTS System
QF06_RS20710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
QF06_RS20710	COG2190	(PTS) system