locus-tag	class	description
C5I45_RS00020	COG0706	membrane insertase activity
C5I45_RS00025	COG1847	R3H domain protein
C5I45_RS00050	COG1192	Involved in chromosome partitioning
C5I45_RS00055	COG1475	DNA binding
C5I45_RS00070	COG3949	Membrane
C5I45_RS00075	COG4481	Protein conserved in bacteria
C5I45_RS00080	COG0243	molybdopterin cofactor binding
C5I45_RS00085	COG0012	GTP binding
C5I45_RS00095	COG0629	single-stranded DNA binding
C5I45_RS00105	COG2169	Transcriptional regulator
C5I45_RS00110	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C5I45_RS00115	COG0708	Exodeoxyribonuclease III
C5I45_RS00120	COG1609	Transcriptional regulator
C5I45_RS00125	COG0346	lactoylglutathione lyase activity
C5I45_RS00130	COG2814	Major facilitator Superfamily
C5I45_RS00130	COG0477	Major facilitator Superfamily
C5I45_RS00135	COG1266	CAAX protease self-immunity
C5I45_RS00140	COG1331	Highly conserved protein containing a thioredoxin domain
C5I45_RS00145	COG1331	Highly conserved protein containing a thioredoxin domain
C5I45_RS00150	COG1811	Na channel or pump
C5I45_RS00155	COG0789	Transcriptional regulator
C5I45_RS00155	COG4978	Transcriptional regulator
C5I45_RS00165	COG0697	spore germination
C5I45_RS00170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C5I45_RS00200	COG1028	Short-chain dehydrogenase reductase Sdr
C5I45_RS00205	COG0583	DNA-binding transcription factor activity
C5I45_RS00210	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C5I45_RS00225	COG1846	Transcriptional regulator
C5I45_RS00230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C5I45_RS00235	COG1846	Transcriptional regulator
C5I45_RS00240	COG0778	Nitroreductase
C5I45_RS00250	COG2211	Major facilitator Superfamily
C5I45_RS00255	COG2318	DinB family
C5I45_RS00260	COG1802	Transcriptional regulator
C5I45_RS00265	COG1621	beta-fructofuranosidase activity
C5I45_RS00270	COG1621	beta-fructofuranosidase activity
C5I45_RS00275	COG0697	spore germination
C5I45_RS00295	COG1733	regulation of RNA biosynthetic process
C5I45_RS00300	COG5577	PFAM Coat F domain
C5I45_RS00310	COG4241	membrane
C5I45_RS00315	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
C5I45_RS00335	COG0438	transferase activity, transferring glycosyl groups
C5I45_RS00340	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
C5I45_RS00350	COG0297	glycogen (starch) synthase activity
C5I45_RS00355	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C5I45_RS00360	COG3093	addiction module antidote protein HigA
C5I45_RS00375	COG0305	Participates in initiation and elongation during chromosome replication
C5I45_RS00380	COG0346	lactoylglutathione lyase activity
C5I45_RS00415	COG0745	RESPONSE REGULATOR receiver
C5I45_RS00420	COG5002	protein histidine kinase activity
C5I45_RS00425	COG4863	YycH protein
C5I45_RS00430	COG4853	Protein conserved in bacteria
C5I45_RS00435	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C5I45_RS00440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C5I45_RS00450	COG5002	protein histidine kinase activity
C5I45_RS00455	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C5I45_RS00470	COG0488	(ABC) transporter
C5I45_RS00480	COG3829	transcription factor binding
C5I45_RS00485	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C5I45_RS00490	COG0833	amino acid
C5I45_RS00495	COG0010	Belongs to the arginase family
C5I45_RS00500	COG0457	Tetratricopeptide repeat
C5I45_RS00505	COG0456	acetyltransferase
C5I45_RS00510	COG0667	Aldo Keto reductase
C5I45_RS00515	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
C5I45_RS00570	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C5I45_RS00575	COG2068	MobA-Related Protein
C5I45_RS00590	COG2080	2 iron, 2 sulfur cluster binding
C5I45_RS00600	COG1113	amino acid transport
C5I45_RS00605	COG3634	alkyl hydroperoxide reductase activity
C5I45_RS00610	COG0450	alkyl hydroperoxide reductase
C5I45_RS00620	COG1714	RDD family
C5I45_RS00625	COG2814	Major facilitator Superfamily
C5I45_RS00630	COG0640	Transcriptional regulator
C5I45_RS00640	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C5I45_RS00645	COG1012	belongs to the aldehyde dehydrogenase family
C5I45_RS00650	COG1309	transcriptional regulator
C5I45_RS00660	COG3239	Fatty acid desaturase
C5I45_RS00665	COG4585	Histidine kinase
C5I45_RS00670	COG2197	response regulator
C5I45_RS00675	COG1028	Short-chain dehydrogenase reductase Sdr
C5I45_RS00690	COG2814	Major facilitator Superfamily
C5I45_RS00695	COG0667	Aldo Keto reductase
C5I45_RS00700	COG1349	DNA-binding transcription factor activity
C5I45_RS00730	COG2814	Major facilitator Superfamily
C5I45_RS00740	COG1082	Xylose isomerase domain protein TIM barrel
C5I45_RS00755	COG0745	RESPONSE REGULATOR receiver
C5I45_RS00760	COG2205	protein histidine kinase activity
C5I45_RS00765	COG1136	(ABC) transporter
C5I45_RS00770	COG0577	efflux transmembrane transporter activity
C5I45_RS00775	COG5294	Protein conserved in bacteria
C5I45_RS00780	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C5I45_RS00810	COG0561	phosphatase activity
C5I45_RS00815	COG2390	Transcriptional regulator
C5I45_RS00825	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C5I45_RS00830	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
C5I45_RS00835	COG0833	amino acid
C5I45_RS00840	COG0010	Belongs to the arginase family
C5I45_RS00865	COG3507	Belongs to the glycosyl hydrolase 43 family
C5I45_RS00870	COG0494	nUDIX hydrolase
C5I45_RS00880	COG0589	response to stress
C5I45_RS00885	COG0697	spore germination
C5I45_RS00980	COG0513	Belongs to the DEAD box helicase family
C5I45_RS00985	COG2270	Major facilitator Superfamily
C5I45_RS00995	COG2273	Hydrolase Family 16
C5I45_RS01000	COG2851	Citrate transporter
C5I45_RS01005	COG0753	catalase activity
C5I45_RS01005	COG0693	protein deglycase activity
C5I45_RS01020	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C5I45_RS01025	COG0500	methyltransferase
C5I45_RS01030	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C5I45_RS01035	COG4894	glucomannan catabolic process
C5I45_RS01045	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C5I45_RS01055	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C5I45_RS01060	COG2508	Transcriptional regulator
C5I45_RS01065	COG3842	ATPase activity
C5I45_RS01070	COG0726	polysaccharide deacetylase
C5I45_RS01075	COG3493	citrate carrier protein
C5I45_RS01080	COG1271	oxidase subunit
C5I45_RS01085	COG1294	oxidase, subunit
C5I45_RS01090	COG4988	ABC transporter
C5I45_RS01095	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C5I45_RS01100	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C5I45_RS01105	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C5I45_RS01110	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
C5I45_RS01115	COG0753	catalase activity
C5I45_RS01125	COG1482	cell wall glycoprotein biosynthetic process
C5I45_RS01130	COG1940	carbohydrate kinase activity
C5I45_RS01135	COG2723	6-phospho-beta-galactosidase activity
C5I45_RS01140	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C5I45_RS01145	COG1447	Phosphotransferase system cellobiose-specific component IIA
C5I45_RS01150	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C5I45_RS01155	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C5I45_RS01160	COG0640	Transcriptional regulator
C5I45_RS01170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C5I45_RS01175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C5I45_RS01190	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5I45_RS01190	COG3711	transcriptional antiterminator
C5I45_RS01195	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C5I45_RS01200	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C5I45_RS01205	COG1447	Phosphotransferase system cellobiose-specific component IIA
C5I45_RS01210	COG1486	melibiose metabolic process
C5I45_RS01215	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C5I45_RS01220	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
C5I45_RS01230	COG1696	Membrane protein involved in D-alanine export
C5I45_RS01255	COG1575	Belongs to the MenA family. Type 1 subfamily
C5I45_RS01260	COG2357	RelA SpoT domain protein
C5I45_RS01265	COG1442	glycosyl transferase family 8
C5I45_RS01270	COG1404	Belongs to the peptidase S8 family
C5I45_RS01275	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C5I45_RS01280	COG0346	lactoylglutathione lyase activity
C5I45_RS01285	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C5I45_RS01290	COG0789	Transcriptional regulator
C5I45_RS01295	COG4895	conserved protein (DUF2196)
C5I45_RS01300	COG1346	cytolysis
C5I45_RS01310	COG0583	DNA-binding transcription factor activity
C5I45_RS01330	COG2822	iron ion transport
C5I45_RS01335	COG2837	iron assimilation
C5I45_RS01340	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C5I45_RS01360	COG1309	transcriptional regulator
C5I45_RS01365	COG2246	polysaccharide biosynthetic process
C5I45_RS01370	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C5I45_RS01370	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C5I45_RS01375	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
C5I45_RS01380	COG2261	transglycosylase associated protein
C5I45_RS01385	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C5I45_RS01390	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C5I45_RS01410	COG0454	-acetyltransferase
C5I45_RS01415	COG0772	Belongs to the SEDS family
C5I45_RS01420	COG0778	Nitroreductase
C5I45_RS01425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C5I45_RS01430	COG1404	Belongs to the peptidase S8 family
C5I45_RS01440	COG3711	transcriptional antiterminator
C5I45_RS01445	COG1263	PTS System
C5I45_RS01445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C5I45_RS01450	COG1621	beta-fructofuranosidase activity
C5I45_RS01460	COG0351	phosphomethylpyrimidine kinase
C5I45_RS01465	COG1695	Transcriptional regulator
C5I45_RS01480	COG1216	Glycosyl transferase, family 2
C5I45_RS01495	COG2233	PERMEase
C5I45_RS01500	COG2363	Small membrane protein
C5I45_RS01510	COG0463	Glycosyl transferase, family 2
C5I45_RS01515	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C5I45_RS01520	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C5I45_RS01525	COG0456	acetyltransferase
C5I45_RS01530	COG2089	acid synthase
C5I45_RS01535	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
C5I45_RS01540	COG3980	spore coat polysaccharide biosynthesis protein
C5I45_RS01545	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C5I45_RS01550	COG1088	dTDP-glucose 4,6-dehydratase activity
C5I45_RS01555	COG1091	dTDP-4-dehydrorhamnose reductase activity
C5I45_RS01560	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
C5I45_RS01570	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C5I45_RS01575	COG1012	belongs to the aldehyde dehydrogenase family
C5I45_RS01580	COG4187	Peptidase family M20/M25/M40
C5I45_RS01585	COG0833	amino acid
C5I45_RS01590	COG2814	Major facilitator Superfamily
C5I45_RS01595	COG2814	Major facilitator Superfamily
C5I45_RS01625	COG0436	Aminotransferase
C5I45_RS01630	COG1028	Short-chain dehydrogenase reductase Sdr
C5I45_RS01640	COG0280	phosphate acetyltransferase
C5I45_RS01645	COG2855	membrane
C5I45_RS01650	COG0583	DNA-binding transcription factor activity
C5I45_RS01670	COG1695	Transcriptional regulator
C5I45_RS01685	COG1078	dGTPase activity
C5I45_RS01690	COG3465	dGTPase activity
C5I45_RS01695	COG0531	amino acid
C5I45_RS01705	COG1846	Transcriptional regulator
C5I45_RS01710	COG1942	4-Oxalocrotonate Tautomerase
C5I45_RS01715	COG1994	Peptidase M50
C5I45_RS01730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C5I45_RS01735	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
C5I45_RS01740	COG0010	Belongs to the arginase family
C5I45_RS01785	COG0457	Tetratricopeptide repeat
C5I45_RS01790	COG4506	Protein conserved in bacteria
C5I45_RS01800	COG2223	nitrite transmembrane transporter activity
C5I45_RS01805	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C5I45_RS01815	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C5I45_RS01820	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C5I45_RS01825	COG1140	nitrate reductase beta subunit
C5I45_RS01830	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C5I45_RS01835	COG2181	nitrate reductase activity
C5I45_RS01845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C5I45_RS01850	COG1132	(ABC) transporter
C5I45_RS01865	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C5I45_RS01870	COG0247	lactate metabolic process
C5I45_RS01870	COG2181	nitrate reductase activity
C5I45_RS01885	COG4821	SIS domain
C5I45_RS01890	COG2204	response regulator
C5I45_RS01895	COG0191	fructose-bisphosphate aldolase activity
C5I45_RS01905	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C5I45_RS01910	COG1494	fructose-1,6-bisphosphatase
C5I45_RS01915	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C5I45_RS01930	COG0281	malic enzyme
C5I45_RS01935	COG0679	Auxin Efflux Carrier
C5I45_RS01940	COG0789	Transcriptional regulator
C5I45_RS01945	COG0346	lactoylglutathione lyase activity
C5I45_RS01950	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C5I45_RS01955	COG2890	protein-(glutamine-N5) methyltransferase activity
C5I45_RS01975	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C5I45_RS01980	COG0009	L-threonylcarbamoyladenylate synthase
C5I45_RS01990	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C5I45_RS01995	COG0698	ribose 5-phosphate isomerase
C5I45_RS02065	COG4836	Membrane
C5I45_RS02075	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C5I45_RS02080	COG2385	sporulation resulting in formation of a cellular spore
C5I45_RS02085	COG2304	oxidoreductase activity
C5I45_RS02090	COG2304	oxidoreductase activity
C5I45_RS02095	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C5I45_RS02105	COG0457	Tetratricopeptide repeat
C5I45_RS02110	COG1994	Peptidase M50
C5I45_RS02115	COG3237	CsbD-like
C5I45_RS02120	COG0831	urea catabolic process
C5I45_RS02135	COG1959	2 iron, 2 sulfur cluster binding
C5I45_RS02145	COG0726	polysaccharide deacetylase
C5I45_RS02160	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C5I45_RS02175	COG1247	-acetyltransferase
C5I45_RS02180	COG0739	heme binding
C5I45_RS02190	COG0671	phosphoesterase, PA-phosphatase related
C5I45_RS02195	COG0772	Belongs to the SEDS family
C5I45_RS02200	COG0347	Belongs to the P(II) protein family
C5I45_RS02205	COG0004	ammonium transporteR
C5I45_RS02210	COG1335	isochorismatase
C5I45_RS02215	COG0477	Major facilitator Superfamily
C5I45_RS02220	COG1953	Uracil, thiamine, allantoin
C5I45_RS02225	COG2814	Major facilitator Superfamily
C5I45_RS02230	COG1846	Transcriptional regulator
C5I45_RS02235	COG1609	Transcriptional regulator
C5I45_RS02240	COG1077	Cell shape determining protein MreB Mrl
C5I45_RS02245	COG4786	Flagellar basal body rod
C5I45_RS02250	COG4786	Flagellar basal body rod
C5I45_RS02255	COG0457	Tetratricopeptide repeat
C5I45_RS02280	COG0629	single-stranded DNA binding
C5I45_RS02285	COG1349	DNA-binding transcription factor activity
C5I45_RS02290	COG0561	phosphatase activity
C5I45_RS02295	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C5I45_RS02300	COG4715	Zinc finger, swim domain protein
C5I45_RS02315	COG3944	biosynthesis protein
C5I45_RS02320	COG0489	protein tyrosine kinase activity
C5I45_RS02325	COG4464	protein tyrosine phosphatase activity
C5I45_RS02330	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C5I45_RS02335	COG3878	Protein conserved in bacteria
C5I45_RS02350	COG5444	nuclease activity
C5I45_RS02360	COG0583	DNA-binding transcription factor activity
C5I45_RS02365	COG0655	NAD(P)H dehydrogenase (quinone) activity
C5I45_RS02375	COG2059	Chromate
C5I45_RS02380	COG2059	Chromate
C5I45_RS02385	COG1522	sequence-specific DNA binding
C5I45_RS02390	COG0405	Gamma-glutamyltransferase
C5I45_RS02400	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C5I45_RS02410	COG5337	Spore coat protein CotH
C5I45_RS02425	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C5I45_RS02430	COG0583	DNA-binding transcription factor activity
C5I45_RS02435	COG0028	Belongs to the TPP enzyme family
C5I45_RS02440	COG3527	Alpha-acetolactate decarboxylase
C5I45_RS02445	COG2249	NAD(P)H dehydrogenase (quinone) activity
C5I45_RS02450	COG3103	Sh3 type 3 domain protein
C5I45_RS02455	COG1879	ABC-type sugar transport system periplasmic component
C5I45_RS02460	COG1172	Belongs to the binding-protein-dependent transport system permease family
C5I45_RS02465	COG1129	ABC transporter
C5I45_RS02475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C5I45_RS02480	COG1609	Transcriptional regulator
C5I45_RS02490	COG0814	amino acid
C5I45_RS02495	COG0697	spore germination
C5I45_RS02505	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C5I45_RS02515	COG2843	Capsule synthesis protein
C5I45_RS02525	COG0791	NLP P60 protein
C5I45_RS02530	COG2433	Pfam Transposase IS66
C5I45_RS02535	COG0561	phosphatase activity
C5I45_RS02540	COG1316	TRANSCRIPTIONal
C5I45_RS02545	COG2814	Major facilitator Superfamily
C5I45_RS02550	COG1215	transferase activity, transferring glycosyl groups
C5I45_RS02560	COG0814	amino acid
C5I45_RS02565	COG0697	spore germination
C5I45_RS02570	COG1482	cell wall glycoprotein biosynthetic process
C5I45_RS02575	COG4193	domain, Protein
C5I45_RS02580	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C5I45_RS02585	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
C5I45_RS02590	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C5I45_RS02600	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C5I45_RS02605	COG1682	transport, permease protein
C5I45_RS02610	COG1134	teichoic acid transport
C5I45_RS02615	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C5I45_RS02620	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C5I45_RS02625	COG1316	TRANSCRIPTIONal
C5I45_RS02635	COG2247	cell wall binding repeat
C5I45_RS02635	COG2385	sporulation resulting in formation of a cellular spore
C5I45_RS02640	COG0860	N-Acetylmuramoyl-L-alanine amidase
C5I45_RS02640	COG2247	cell wall binding repeat
C5I45_RS02650	COG2244	polysaccharide biosynthetic process
C5I45_RS02655	COG0297	glycogen (starch) synthase activity
C5I45_RS02655	COG0438	transferase activity, transferring glycosyl groups
C5I45_RS02660	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C5I45_RS02665	COG3307	-O-antigen
C5I45_RS02670	COG3206	protein involved in exopolysaccharide biosynthesis
C5I45_RS02675	COG1215	transferase activity, transferring glycosyl groups
C5I45_RS02680	COG0438	transferase activity, transferring glycosyl groups
C5I45_RS02685	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C5I45_RS02690	COG1316	TRANSCRIPTIONal
C5I45_RS02695	COG1739	Uncharacterized protein family UPF0029
C5I45_RS02700	COG4585	Histidine kinase
C5I45_RS02705	COG2197	response regulator
C5I45_RS02710	COG1307	EDD domain protein, DegV family
C5I45_RS02715	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
C5I45_RS02725	COG1040	competence protein
C5I45_RS02735	COG2747	anti-sigma28 factor FlgM
C5I45_RS02740	COG3418	PFAM FlgN family protein
C5I45_RS02745	COG1256	bacterial-type flagellum assembly
C5I45_RS02745	COG4786	Flagellar basal body rod
C5I45_RS02750	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C5I45_RS02770	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C5I45_RS02775	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C5I45_RS02780	COG1516	flagellar protein fliS
C5I45_RS02795	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C5I45_RS02810	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C5I45_RS02815	COG2010	Cytochrome c
C5I45_RS02820	COG2884	Cell division ATP-binding protein ftsE
C5I45_RS02825	COG2177	Part of the ABC transporter FtsEX involved in
C5I45_RS02830	COG3420	alginic acid biosynthetic process
C5I45_RS02835	COG3409	Peptidoglycan-binding domain 1 protein
C5I45_RS02835	COG0793	Belongs to the peptidase S41A family
C5I45_RS02845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C5I45_RS02880	COG2814	Major facilitator Superfamily
C5I45_RS02885	COG1309	transcriptional regulator
C5I45_RS02890	COG3848	Pyruvate phosphate dikinase
C5I45_RS02890	COG0574	Belongs to the PEP-utilizing enzyme family
C5I45_RS02895	COG4897	Protein conserved in bacteria
C5I45_RS02905	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C5I45_RS02920	COG3595	metallopeptidase activity
C5I45_RS02925	COG1983	PspC domain protein
C5I45_RS02930	COG1950	PFAM Membrane protein of
C5I45_RS02935	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C5I45_RS02940	COG1309	transcriptional regulator
C5I45_RS02945	COG2188	Transcriptional regulator
C5I45_RS02955	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C5I45_RS02975	COG0110	maltose O-acetyltransferase activity
C5I45_RS02980	COG4990	cell redox homeostasis
C5I45_RS02995	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C5I45_RS03020	COG0140	phosphoribosyl-ATP diphosphatase activity
C5I45_RS03020	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C5I45_RS03025	COG1132	(ABC) transporter
C5I45_RS03035	COG0745	RESPONSE REGULATOR receiver
C5I45_RS03040	COG5002	protein histidine kinase activity
C5I45_RS03045	COG0457	Tetratricopeptide repeat
C5I45_RS03050	COG0791	NLP P60 protein
C5I45_RS03050	COG3883	PFAM NLP P60 protein
C5I45_RS03055	COG0492	ferredoxin-NADP+ reductase activity
C5I45_RS03060	COG1051	belongs to the nudix hydrolase family
C5I45_RS03070	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C5I45_RS03080	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5I45_RS03085	COG2162	N-hydroxyarylamine O-acetyltransferase activity
C5I45_RS03090	COG4290	ribonuclease
C5I45_RS03095	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C5I45_RS03105	COG0288	reversible hydration of carbon dioxide
C5I45_RS03110	COG0659	secondary active sulfate transmembrane transporter activity
C5I45_RS03115	COG1694	Mazg nucleotide pyrophosphohydrolase
C5I45_RS03120	COG1611	Belongs to the LOG family
C5I45_RS03125	COG0477	Major facilitator Superfamily
C5I45_RS03125	COG2814	Major facilitator Superfamily
C5I45_RS03130	COG2828	Protein conserved in bacteria
C5I45_RS03135	COG0583	DNA-binding transcription factor activity
C5I45_RS03145	COG1609	Transcriptional regulator
C5I45_RS03150	COG2223	nitrite transmembrane transporter activity
C5I45_RS03205	COG3479	Phenolic acid decarboxylase
C5I45_RS03210	COG0456	acetyltransferase
C5I45_RS03215	COG2364	Membrane
C5I45_RS03220	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C5I45_RS03230	COG2272	Belongs to the type-B carboxylesterase lipase family
C5I45_RS03235	COG1396	sequence-specific DNA binding
C5I45_RS03240	COG3944	biosynthesis protein
C5I45_RS03245	COG0489	protein tyrosine kinase activity
C5I45_RS03250	COG1086	Polysaccharide biosynthesis protein
C5I45_RS03255	COG0438	transferase activity, transferring glycosyl groups
C5I45_RS03260	COG1215	transferase activity, transferring glycosyl groups
C5I45_RS03265	COG0438	transferase activity, transferring glycosyl groups
C5I45_RS03275	COG1216	Glycosyl transferase, family 2
C5I45_RS03280	COG5039	Polysaccharide pyruvyl transferase
C5I45_RS03285	COG1216	Glycosyl transferase, family 2
C5I45_RS03290	COG2244	polysaccharide biosynthetic process
C5I45_RS03295	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C5I45_RS03300	COG0110	maltose O-acetyltransferase activity
C5I45_RS03305	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C5I45_RS03310	COG5039	Polysaccharide pyruvyl transferase
C5I45_RS03320	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C5I45_RS03325	COG1620	l-lactate permease
C5I45_RS03330	COG2186	Transcriptional regulator
C5I45_RS03335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C5I45_RS03360	COG1070	Carbohydrate kinase
C5I45_RS03365	COG1737	Transcriptional regulator
C5I45_RS03370	COG1113	amino acid transport
C5I45_RS03375	COG0697	spore germination
C5I45_RS03380	COG0583	DNA-binding transcription factor activity
C5I45_RS03390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C5I45_RS03395	COG1609	Transcriptional regulator
C5I45_RS03400	COG2814	Major facilitator Superfamily
C5I45_RS03405	COG2390	Transcriptional regulator
C5I45_RS03410	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C5I45_RS03420	COG0126	phosphoglycerate kinase activity
C5I45_RS03440	COG2234	aminopeptidase activity
C5I45_RS03450	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C5I45_RS03455	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C5I45_RS03460	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C5I45_RS03475	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C5I45_RS03490	COG0456	acetyltransferase
C5I45_RS03495	COG4640	response to antibiotic
C5I45_RS03500	COG3064	Membrane
C5I45_RS03510	COG2095	MarC family integral membrane protein
C5I45_RS03515	COG1510	regulation of RNA biosynthetic process
C5I45_RS03520	COG0517	IMP dehydrogenase activity
C5I45_RS03520	COG1125	glycine betaine transport
C5I45_RS03525	COG1174	glycine betaine transport
C5I45_RS03530	COG1732	Glycine betaine
C5I45_RS03535	COG1174	glycine betaine transport
C5I45_RS03540	COG1510	regulation of RNA biosynthetic process
C5I45_RS03545	COG1125	glycine betaine transport
C5I45_RS03545	COG0517	IMP dehydrogenase activity
C5I45_RS03550	COG1174	glycine betaine transport
C5I45_RS03555	COG1732	Glycine betaine
C5I45_RS03560	COG1174	glycine betaine transport
C5I45_RS03565	COG1131	(ABC) transporter
C5I45_RS03590	COG1733	regulation of RNA biosynthetic process
C5I45_RS03595	COG1396	sequence-specific DNA binding
C5I45_RS03600	COG1396	sequence-specific DNA binding
C5I45_RS03605	COG1476	TRANSCRIPTIONal
C5I45_RS03610	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C5I45_RS03615	COG1647	Serine aminopeptidase, S33
C5I45_RS03620	COG0557	exoribonuclease II activity
C5I45_RS03635	COG2732	(Barnase) inhibitor
C5I45_RS03640	COG1028	Short-chain dehydrogenase reductase Sdr
C5I45_RS03645	COG0583	DNA-binding transcription factor activity
C5I45_RS03650	COG0454	-acetyltransferase
C5I45_RS03655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5I45_RS03660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5I45_RS03665	COG0765	amino acid transport
C5I45_RS03670	COG0765	amino acid transport
C5I45_RS03675	COG1126	abc transporter atp-binding protein
C5I45_RS03680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C5I45_RS03685	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C5I45_RS03690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C5I45_RS03705	COG2814	Major facilitator Superfamily
C5I45_RS03725	COG0673	inositol 2-dehydrogenase activity
C5I45_RS03730	COG1937	Protein conserved in bacteria
C5I45_RS03735	COG2608	mercury ion transmembrane transporter activity
C5I45_RS03740	COG2217	Heavy metal translocating P-type atpase
C5I45_RS03745	COG2217	Heavy metal translocating P-type atpase
C5I45_RS03750	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C5I45_RS03755	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C5I45_RS03765	COG2860	membrane
C5I45_RS03770	COG3973	AAA domain
C5I45_RS03775	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C5I45_RS03800	COG0656	L-ascorbic acid biosynthetic process
C5I45_RS03805	COG0842	Transport permease protein
C5I45_RS03815	COG1131	(ABC) transporter
C5I45_RS03820	COG3850	Histidine kinase
C5I45_RS03825	COG2197	response regulator
C5I45_RS03830	COG4149	molybdate abc transporter
C5I45_RS03835	COG0725	ABC transporter, periplasmic molybdate-binding protein
C5I45_RS03840	COG1910	domain protein
C5I45_RS03845	COG1368	sulfuric ester hydrolase activity
C5I45_RS03850	COG1988	membrane-bound metal-dependent
C5I45_RS03865	COG0531	amino acid
C5I45_RS03870	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
C5I45_RS03875	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C5I45_RS03880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C5I45_RS03885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C5I45_RS03890	COG1120	ATPase activity
C5I45_RS03900	COG2140	Oxalate decarboxylase
C5I45_RS03910	COG1191	sigma factor activity
C5I45_RS03920	COG0745	RESPONSE REGULATOR receiver
C5I45_RS03925	COG2205	protein histidine kinase activity
C5I45_RS03930	COG3386	PFAM SMP-30 Gluconolaconase
C5I45_RS03935	COG1028	Short-chain dehydrogenase reductase Sdr
C5I45_RS03940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C5I45_RS03945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C5I45_RS03950	COG1120	ATPase activity
C5I45_RS03955	COG2096	Adenosyltransferase
C5I45_RS03960	COG2814	Major facilitator Superfamily
C5I45_RS03965	COG4758	membrane
C5I45_RS03970	COG1842	Phage shock protein A
C5I45_RS03975	COG3595	metallopeptidase activity
C5I45_RS03980	COG4758	membrane
C5I45_RS03985	COG4585	Histidine kinase
C5I45_RS03990	COG2197	response regulator
C5I45_RS04000	COG0814	amino acid
C5I45_RS04005	COG0697	spore germination
C5I45_RS04015	COG0114	fumarate hydratase activity
C5I45_RS04020	COG1309	transcriptional regulator
C5I45_RS04030	COG2205	protein histidine kinase activity
C5I45_RS04030	COG2770	Histidine kinase
C5I45_RS04035	COG0745	RESPONSE REGULATOR receiver
C5I45_RS04040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C5I45_RS04045	COG0783	Belongs to the Dps family
C5I45_RS04050	COG1028	Short-chain dehydrogenase reductase Sdr
C5I45_RS04065	COG1120	ATPase activity
C5I45_RS04085	COG0583	DNA-binding transcription factor activity
C5I45_RS04090	COG0477	Major facilitator Superfamily
C5I45_RS04095	COG1846	Transcriptional regulator
C5I45_RS04100	COG5577	PFAM Coat F domain
C5I45_RS04120	COG1024	Enoyl-CoA hydratase
C5I45_RS04120	COG1250	3-hydroxyacyl-CoA dehydrogenase
C5I45_RS04125	COG0183	Belongs to the thiolase family
C5I45_RS04130	COG1960	acyl-CoA dehydrogenase activity
C5I45_RS04135	COG1393	Belongs to the ArsC family
C5I45_RS04150	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C5I45_RS04155	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C5I45_RS04165	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C5I45_RS04170	COG2011	ABC-type metal ion transport system permease component
C5I45_RS04175	COG1464	Belongs to the NlpA lipoprotein family
C5I45_RS04180	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C5I45_RS04190	COG0396	ATPase activity
C5I45_RS04195	COG0719	Fe-S assembly protein
C5I45_RS04200	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C5I45_RS04205	COG0822	iron-sulfur transferase activity
C5I45_RS04210	COG0719	Fe-S assembly protein
C5I45_RS04215	COG3409	Peptidoglycan-binding domain 1 protein
C5I45_RS04225	COG2226	methyltransferase
C5I45_RS04230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C5I45_RS04235	COG0322	excinuclease ABC activity
C5I45_RS04250	COG0789	Transcriptional regulator
C5I45_RS04255	COG2222	sugar isomerase
C5I45_RS04260	COG1653	transport
C5I45_RS04265	COG1175	transmembrane transport
C5I45_RS04270	COG0395	ABC-type sugar transport system, permease component
C5I45_RS04275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C5I45_RS04280	COG2188	Transcriptional regulator
C5I45_RS04285	COG3842	ATPase activity
C5I45_RS04290	COG2356	endonuclease I
C5I45_RS04295	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C5I45_RS04300	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C5I45_RS04305	COG2814	Major facilitator Superfamily
C5I45_RS04330	COG2508	Transcriptional regulator
C5I45_RS04345	COG1801	Protein of unknown function DUF72
C5I45_RS04350	COG0730	response to heat
C5I45_RS04355	COG0737	Belongs to the 5'-nucleotidase family
C5I45_RS04365	COG0739	heme binding
C5I45_RS04380	COG4470	Protein conserved in bacteria
C5I45_RS04385	COG2445	Protein of unknown function DUF86
C5I45_RS04390	COG0647	UMP catabolic process
C5I45_RS04395	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C5I45_RS04400	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C5I45_RS04405	COG0460	homoserine dehydrogenase
C5I45_RS04410	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C5I45_RS04420	COG0823	Involved in the tonB-independent uptake of proteins
C5I45_RS04420	COG4946	Tricorn protease homolog
C5I45_RS04420	COG1506	peptidase
C5I45_RS04425	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
C5I45_RS04430	COG4837	Protein of unknown function (DUF1462)
C5I45_RS04435	COG1252	NADH dehydrogenase
C5I45_RS04445	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C5I45_RS04455	COG0316	Belongs to the HesB IscA family
C5I45_RS04460	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
C5I45_RS04485	COG1131	(ABC) transporter
C5I45_RS04515	COG1252	NADH dehydrogenase
C5I45_RS04530	COG3584	3D domain protein
C5I45_RS04535	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
C5I45_RS04545	COG2056	Na+-H+ antiporter family
C5I45_RS04550	COG1268	BioY protein
C5I45_RS04555	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C5I45_RS04560	COG2819	hydrolase of the alpha beta superfamily
C5I45_RS04565	COG1028	Short-chain dehydrogenase reductase Sdr
C5I45_RS04570	COG1169	isochorismate synthase
C5I45_RS04575	COG1021	2,3-dihydroxybenzoate-AMP ligase
C5I45_RS04580	COG3433	isochorismatase activity
C5I45_RS04580	COG1535	isochorismatase
C5I45_RS04585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C5I45_RS04590	COG3251	PFAM MbtH domain protein
C5I45_RS04595	COG5634	Uncharacterized conserved protein (DUF2278)
C5I45_RS04600	COG0686	Belongs to the AlaDH PNT family
C5I45_RS04605	COG2508	Transcriptional regulator
C5I45_RS04605	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
C5I45_RS04615	COG1028	Short-chain dehydrogenase reductase Sdr
C5I45_RS04620	COG1418	mRNA catabolic process
C5I45_RS04630	COG0628	permease
C5I45_RS04645	COG5506	Protein of unknown function (DUF1694)
C5I45_RS04650	COG1335	isochorismatase
C5I45_RS04655	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C5I45_RS04660	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
C5I45_RS04685	COG4585	Histidine kinase
C5I45_RS04690	COG2197	response regulator
C5I45_RS04695	COG2050	protein possibly involved in aromatic compounds catabolism
C5I45_RS04700	COG1320	monovalent cation:proton antiporter activity
C5I45_RS04705	COG2212	antiporter activity
C5I45_RS04710	COG1863	multisubunit Na H antiporter MnhE subunit
C5I45_RS04715	COG0651	ATP synthesis coupled electron transport
C5I45_RS04720	COG1006	Multisubunit Na H antiporter MnhC subunit
C5I45_RS04725	COG2111	Na H antiporter
C5I45_RS04730	COG2111	Na H antiporter
C5I45_RS04730	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C5I45_RS04740	COG1079	Belongs to the binding-protein-dependent transport system permease family
C5I45_RS04745	COG4603	Belongs to the binding-protein-dependent transport system permease family
C5I45_RS04750	COG3845	ABC transporter
C5I45_RS04755	COG1744	ABC transporter substrate-binding protein PnrA-like
C5I45_RS04760	COG4565	transcriptional regulatory protein
C5I45_RS04765	COG3290	protein histidine kinase activity
C5I45_RS04775	COG3011	Protein conserved in bacteria
C5I45_RS04780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C5I45_RS04785	COG2814	Major facilitator Superfamily
C5I45_RS04790	COG5018	Exonuclease
C5I45_RS04800	COG2205	protein histidine kinase activity
C5I45_RS04805	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C5I45_RS04815	COG2267	carboxylic ester hydrolase activity
C5I45_RS04820	COG1522	sequence-specific DNA binding
C5I45_RS04825	COG0436	Aminotransferase
C5I45_RS04830	COG1098	S1 RNA binding domain
C5I45_RS04835	COG2155	Conserved Protein
C5I45_RS04840	COG1979	alcohol dehydrogenase
C5I45_RS04845	COG1979	alcohol dehydrogenase
C5I45_RS04855	COG1335	isochorismatase
C5I45_RS04885	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C5I45_RS04900	COG2738	Putative neutral zinc metallopeptidase
C5I45_RS04905	COG1253	flavin adenine dinucleotide binding
C5I45_RS04910	COG0366	Alpha amylase catalytic
C5I45_RS04915	COG0432	Pfam Uncharacterised protein family UPF0047
C5I45_RS04920	COG2070	2-Nitropropane dioxygenase
C5I45_RS04935	COG0840	transmembrane signaling receptor activity
C5I45_RS04940	COG0840	transmembrane signaling receptor activity
C5I45_RS04945	COG0840	transmembrane signaling receptor activity
C5I45_RS04950	COG0840	transmembrane signaling receptor activity
C5I45_RS04955	COG0693	protein deglycase activity
C5I45_RS04960	COG0673	inositol 2-dehydrogenase activity
C5I45_RS04965	COG0628	permease
C5I45_RS05020	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C5I45_RS05020	COG1017	nitric oxide dioxygenase activity
C5I45_RS05025	COG1705	Flagellar rod assembly protein muramidase FlgJ
C5I45_RS05030	COG0569	domain protein
C5I45_RS05040	COG1510	regulation of RNA biosynthetic process
C5I45_RS05045	COG1012	belongs to the aldehyde dehydrogenase family
C5I45_RS05050	COG1454	alcohol dehydrogenase
C5I45_RS05060	COG2318	DinB family
C5I45_RS05065	COG1585	Membrane protein implicated in regulation of membrane protease activity
C5I45_RS05070	COG2268	Band 7 protein
C5I45_RS05075	COG3859	Proton-coupled thiamine transporter YuaJ
C5I45_RS05200	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
C5I45_RS05205	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C5I45_RS05210	COG1169	isochorismate synthase
C5I45_RS05220	COG0596	Alpha beta hydrolase
C5I45_RS05225	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C5I45_RS05235	COG4948	Mandelate Racemase Muconate Lactonizing
C5I45_RS05250	COG1294	oxidase, subunit
C5I45_RS05255	COG1271	oxidase subunit
C5I45_RS05265	COG0288	reversible hydration of carbon dioxide
C5I45_RS05290	COG0783	Belongs to the Dps family
C5I45_RS05295	COG4824	toxin secretion phage lysis holin
C5I45_RS05300	COG0494	nUDIX hydrolase
C5I45_RS05305	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C5I45_RS05310	COG1116	anion transmembrane transporter activity
C5I45_RS05315	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C5I45_RS05320	COG1506	peptidase
C5I45_RS05340	COG0367	asparagine synthase
C5I45_RS05345	COG1113	amino acid transport
C5I45_RS05350	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C5I45_RS05355	COG2267	carboxylic ester hydrolase activity
C5I45_RS05365	COG0584	glycerophosphoryl diester phosphodiesterase
C5I45_RS05375	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
C5I45_RS05380	COG1242	4 iron, 4 sulfur cluster binding
C5I45_RS05385	COG0477	Major facilitator Superfamily
C5I45_RS05390	COG0640	Transcriptional regulator
C5I45_RS05400	COG1725	Transcriptional regulator
C5I45_RS05405	COG1131	(ABC) transporter
C5I45_RS05425	COG1136	(ABC) transporter
C5I45_RS05430	COG0577	efflux transmembrane transporter activity
C5I45_RS05435	COG0745	RESPONSE REGULATOR receiver
C5I45_RS05440	COG2205	protein histidine kinase activity
C5I45_RS05445	COG1136	(ABC) transporter
C5I45_RS05450	COG0577	efflux transmembrane transporter activity
C5I45_RS05455	COG5522	Integral membrane protein (intg_mem_TP0381)
C5I45_RS05460	COG2814	Major facilitator Superfamily
C5I45_RS05465	COG1366	Belongs to the anti-sigma-factor antagonist family
C5I45_RS05465	COG2202	Pas domain
C5I45_RS05480	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C5I45_RS05490	COG1486	melibiose metabolic process
C5I45_RS05495	COG0395	ABC-type sugar transport system, permease component
C5I45_RS05500	COG1175	transmembrane transport
C5I45_RS05505	COG1653	transport
C5I45_RS05510	COG1609	Transcriptional regulator
C5I45_RS05520	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C5I45_RS05525	COG2081	HI0933 family
C5I45_RS05530	COG2244	polysaccharide biosynthetic process
C5I45_RS05535	COG1187	pseudouridine synthase activity
C5I45_RS05540	COG1349	DNA-binding transcription factor activity
C5I45_RS05550	COG1131	(ABC) transporter
C5I45_RS05555	COG4473	ABC transporter
C5I45_RS05560	COG2252	PERMEase
C5I45_RS05565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C5I45_RS05570	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C5I45_RS05575	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C5I45_RS05585	COG1597	lipid kinase activity
C5I45_RS05590	COG0510	thiamine kinase activity
C5I45_RS05605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C5I45_RS05610	COG0281	malic enzyme
C5I45_RS05615	COG5584	Small secreted protein
C5I45_RS05620	COG1363	Peptidase, m42
C5I45_RS05630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C5I45_RS05640	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C5I45_RS05645	COG1674	ftsk spoiiie
C5I45_RS05655	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
C5I45_RS05660	COG4980	gas vesicle protein
C5I45_RS05665	COG3118	belongs to the thioredoxin family
C5I45_RS05670	COG1605	Chorismate mutase
C5I45_RS05670	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
C5I45_RS05675	COG1609	Transcriptional regulator
C5I45_RS05680	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C5I45_RS05685	COG1360	Flagellar Motor Protein
C5I45_RS05690	COG0123	including yeast histone deacetylase and acetoin utilization protein
C5I45_RS05695	COG0517	IMP dehydrogenase activity
C5I45_RS05700	COG0454	-acetyltransferase
C5I45_RS05705	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C5I45_RS05730	COG1378	Sugar-specific transcriptional regulator TrmB
C5I45_RS05735	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C5I45_RS05760	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C5I45_RS05760	COG1017	nitric oxide dioxygenase activity
C5I45_RS05800	COG4282	regulation of fungal-type cell wall biogenesis
C5I45_RS05805	COG1012	belongs to the aldehyde dehydrogenase family
C5I45_RS05820	COG2203	Gaf domain
C5I45_RS05820	COG2199	diguanylate cyclase activity
C5I45_RS05825	COG1956	GAF domain-containing protein
C5I45_RS05830	COG1309	transcriptional regulator
C5I45_RS05835	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C5I45_RS05845	COG1114	Component of the transport system for branched-chain amino acids
C5I45_RS05850	COG1104	cysteine desulfurase activity
C5I45_RS05865	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C5I45_RS05870	COG1574	metal-dependent hydrolase with the TIM-barrel fold
C5I45_RS05875	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C5I45_RS05880	COG0616	signal peptide processing
C5I45_RS05885	COG1714	RDD family
C5I45_RS05895	COG3874	Sporulation protein YtfJ
C5I45_RS05900	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
C5I45_RS05905	COG0827	DNA restriction-modification system
C5I45_RS05915	COG0521	Mo-molybdopterin cofactor biosynthetic process
C5I45_RS05930	COG1028	Short-chain dehydrogenase reductase Sdr
C5I45_RS05940	COG4109	DRTGG domain
C5I45_RS05950	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C5I45_RS05970	COG0587	DNA-directed DNA polymerase activity
C5I45_RS05975	COG0281	malic enzyme
C5I45_RS05995	COG0469	pyruvate kinase activity
C5I45_RS06000	COG3030	protein affecting phage T7 exclusion by the F plasmid
C5I45_RS06005	COG0628	permease
C5I45_RS06035	COG0457	Tetratricopeptide repeat
C5I45_RS06040	COG0372	Belongs to the citrate synthase family
C5I45_RS06045	COG0538	isocitrate dehydrogenase activity
C5I45_RS06055	COG0745	RESPONSE REGULATOR receiver
C5I45_RS06060	COG5002	protein histidine kinase activity
C5I45_RS06065	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C5I45_RS06065	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C5I45_RS06070	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C5I45_RS06075	COG1971	Probably functions as a manganese efflux pump
C5I45_RS06080	COG0237	dephospho-CoA kinase activity
C5I45_RS06085	COG0656	L-ascorbic acid biosynthetic process
C5I45_RS06090	COG2814	Major facilitator Superfamily
C5I45_RS06095	COG1733	regulation of RNA biosynthetic process
C5I45_RS06100	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C5I45_RS06115	COG3611	Membrane attachment protein
C5I45_RS06120	COG1484	DNA-dependent DNA replication
C5I45_RS06125	COG0398	Pfam SNARE associated Golgi protein
C5I45_RS06140	COG1011	Hydrolase
C5I45_RS06145	COG3275	phosphorelay sensor kinase activity
C5I45_RS06150	COG3279	Response regulator of the LytR AlgR family
C5I45_RS06155	COG1380	Effector of murein hydrolase LrgA
C5I45_RS06160	COG1346	cytolysis
C5I45_RS06165	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C5I45_RS06175	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C5I45_RS06180	COG3326	Membrane
C5I45_RS06190	COG1363	Peptidase, m42
C5I45_RS06195	COG3507	Belongs to the glycosyl hydrolase 43 family
C5I45_RS06200	COG2160	L-arabinose isomerase activity
C5I45_RS06205	COG1069	ribulokinase activity
C5I45_RS06210	COG0235	Class ii aldolase
C5I45_RS06215	COG0647	UMP catabolic process
C5I45_RS06225	COG1653	transport
C5I45_RS06230	COG1175	transmembrane transport
C5I45_RS06235	COG0395	ABC-type sugar transport system, permease component
C5I45_RS06240	COG3534	alpha-L-arabinofuranosidase
C5I45_RS06245	COG1966	Carbon starvation protein
C5I45_RS06250	COG0247	lactate metabolic process
C5I45_RS06255	COG0277	FAD linked oxidase domain protein
C5I45_RS06260	COG3835	regulator
C5I45_RS06270	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C5I45_RS06275	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C5I45_RS06280	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C5I45_RS06280	COG0072	phenylalanine-tRNA ligase activity
C5I45_RS06295	COG1286	toxin biosynthetic process
C5I45_RS06300	COG1796	DNA polymerase
C5I45_RS06300	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C5I45_RS06310	COG3766	membrane
C5I45_RS06320	COG0318	PFAM AMP-dependent synthetase and ligase
C5I45_RS06325	COG1309	transcriptional regulator
C5I45_RS06330	COG1024	Enoyl-CoA hydratase
C5I45_RS06335	COG2086	electron transfer activity
C5I45_RS06340	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C5I45_RS06345	COG3534	alpha-L-arabinofuranosidase
C5I45_RS06350	COG3118	belongs to the thioredoxin family
C5I45_RS06365	COG0527	aspartate kinase activity
C5I45_RS06370	COG1719	4-vinyl reductase, 4VR
C5I45_RS06375	COG2009	succinate dehydrogenase
C5I45_RS06380	COG1053	succinate dehydrogenase
C5I45_RS06385	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C5I45_RS06390	COG0824	Thioesterase
C5I45_RS06395	COG2197	response regulator
C5I45_RS06400	COG1846	Transcriptional regulator
C5I45_RS06410	COG5401	PFAM Sporulation and spore germination
C5I45_RS06420	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C5I45_RS06425	COG0622	Phosphoesterase
C5I45_RS06445	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
C5I45_RS06490	COG0028	Belongs to the TPP enzyme family
C5I45_RS06495	COG0440	acetolactate synthase activity
C5I45_RS06510	COG0473	3-isopropylmalate dehydrogenase activity
C5I45_RS06525	COG1477	protein flavinylation
C5I45_RS06525	COG0457	Tetratricopeptide repeat
C5I45_RS06540	COG0470	DNA polymerase III
C5I45_RS06540	COG1067	ATP-dependent peptidase activity
C5I45_RS06545	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C5I45_RS06565	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C5I45_RS06575	COG1587	Uroporphyrinogen-III synthase
C5I45_RS06580	COG0113	porphobilinogen synthase activity
C5I45_RS06590	COG1388	LysM domain
C5I45_RS06595	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C5I45_RS06605	COG0525	valine-tRNA ligase activity
C5I45_RS06610	COG0285	dihydrofolate synthase activity
C5I45_RS06615	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C5I45_RS06635	COG1077	Cell shape determining protein MreB Mrl
C5I45_RS06645	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C5I45_RS06655	COG2894	cell division
C5I45_RS06660	COG0739	heme binding
C5I45_RS06665	COG1994	Peptidase M50
C5I45_RS06675	COG2868	ribosomal protein
C5I45_RS06680	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C5I45_RS06685	COG3290	protein histidine kinase activity
C5I45_RS06700	COG0077	Prephenate dehydratase
C5I45_RS06705	COG1827	regulation of RNA biosynthetic process
C5I45_RS06710	COG1104	cysteine desulfurase activity
C5I45_RS06715	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C5I45_RS06720	COG0157	Belongs to the NadC ModD family
C5I45_RS06730	COG1388	LysM domain
C5I45_RS06775	COG1862	Preprotein translocase
C5I45_RS06785	COG2323	membrane
C5I45_RS06790	COG2244	polysaccharide biosynthetic process
C5I45_RS06800	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C5I45_RS06800	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C5I45_RS06805	COG0490	domain, Protein
C5I45_RS06810	COG5416	Lipopolysaccharide assembly protein A domain
C5I45_RS06815	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C5I45_RS06815	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
C5I45_RS06825	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C5I45_RS06835	COG3103	Sh3 type 3 domain protein
C5I45_RS06835	COG4991	sh3 domain protein
C5I45_RS06835	COG0860	N-Acetylmuramoyl-L-alanine amidase
C5I45_RS06855	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C5I45_RS06860	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C5I45_RS06865	COG1959	2 iron, 2 sulfur cluster binding
C5I45_RS06870	COG1104	cysteine desulfurase activity
C5I45_RS06880	COG0457	Tetratricopeptide repeat
C5I45_RS06885	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C5I45_RS06890	COG3881	PFAM PRC-barrel domain
C5I45_RS06905	COG0765	amino acid transport
C5I45_RS06910	COG0765	amino acid transport
C5I45_RS06915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5I45_RS06920	COG1126	abc transporter atp-binding protein
C5I45_RS06925	COG0628	permease
C5I45_RS06935	COG4472	Bacterial protein of unknown function (DUF965)
C5I45_RS06950	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C5I45_RS06955	COG4122	O-methyltransferase activity
C5I45_RS06960	COG0826	peptidase U32
C5I45_RS06965	COG0826	peptidase U32
C5I45_RS06980	COG0768	penicillin binding
C5I45_RS07005	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C5I45_RS07010	COG0626	cystathionine gamma-synthase activity
C5I45_RS07020	COG2427	Protein of unknown function (DUF1641)
C5I45_RS07025	COG3383	formate dehydrogenase (NAD+) activity
C5I45_RS07030	COG5609	conserved protein (DUF2294)
C5I45_RS07035	COG2116	formate transmembrane transporter activity
C5I45_RS07050	COG2226	methyltransferase
C5I45_RS07055	COG1309	transcriptional regulator
C5I45_RS07060	COG2124	cytochrome p450
C5I45_RS07060	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C5I45_RS07065	COG2814	Major facilitator Superfamily
C5I45_RS07070	COG0583	DNA-binding transcription factor activity
C5I45_RS07075	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C5I45_RS07085	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5I45_RS07085	COG3711	transcriptional antiterminator
C5I45_RS07090	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C5I45_RS07090	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5I45_RS07090	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C5I45_RS07095	COG1482	cell wall glycoprotein biosynthetic process
C5I45_RS07105	COG0561	phosphatase activity
C5I45_RS07110	COG0561	phosphatase activity
C5I45_RS07120	COG2318	DinB family
C5I45_RS07125	COG0456	acetyltransferase
C5I45_RS07135	COG2814	Major facilitator Superfamily
C5I45_RS07145	COG0563	adenylate kinase activity
C5I45_RS07155	COG3708	Transcriptional regulator
C5I45_RS07155	COG2207	Transcriptional regulator
C5I45_RS07185	COG0398	Pfam SNARE associated Golgi protein
C5I45_RS07195	COG2755	lipolytic protein G-D-S-L family
C5I45_RS07205	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
C5I45_RS07210	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C5I45_RS07215	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C5I45_RS07220	COG1534	Rna-binding protein
C5I45_RS07230	COG1713	HD superfamily hydrolase involved in NAD metabolism
C5I45_RS07235	COG0799	negative regulation of ribosome biogenesis
C5I45_RS07240	COG2226	methyltransferase
C5I45_RS07245	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C5I45_RS07250	COG1596	polysaccharide export
C5I45_RS07250	COG1555	photosystem II stabilization
C5I45_RS07255	COG2131	deaminase
C5I45_RS07260	COG2333	competence protein COMEC
C5I45_RS07260	COG0658	competence protein
C5I45_RS07270	COG1466	dna polymerase III delta subunit
C5I45_RS07285	COG0860	N-Acetylmuramoyl-L-alanine amidase
C5I45_RS07300	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C5I45_RS07330	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C5I45_RS07335	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C5I45_RS07340	COG1283	sodium-dependent phosphate transmembrane transporter activity
C5I45_RS07350	COG1610	YqeY-like protein
C5I45_RS07355	COG1030	water channel activity
C5I45_RS07360	COG4864	UPF0365 protein
C5I45_RS07375	COG0561	phosphatase activity
C5I45_RS07380	COG1702	phosphate starvation-inducible protein PhoH
C5I45_RS07385	COG1480	7TM receptor with intracellular HD hydrolase
C5I45_RS07395	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C5I45_RS07400	COG0295	cytidine deaminase activity
C5I45_RS07405	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C5I45_RS07425	COG0751	glycine-tRNA ligase activity
C5I45_RS07430	COG0517	IMP dehydrogenase activity
C5I45_RS07445	COG0358	DNA primase activity
C5I45_RS07450	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C5I45_RS07455	COG2010	Cytochrome c
C5I45_RS07460	COG2384	SAM-dependent methyltransferase
C5I45_RS07465	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C5I45_RS07480	COG0513	Belongs to the DEAD box helicase family
C5I45_RS07495	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C5I45_RS07500	COG0735	belongs to the Fur family
C5I45_RS07505	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
C5I45_RS07510	COG4709	membrane
C5I45_RS07520	COG1388	LysM domain
C5I45_RS07525	COG5521	maltodextrose utilization protein MalA
C5I45_RS07530	COG2839	Protein conserved in bacteria
C5I45_RS07535	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C5I45_RS07540	COG0477	Major facilitator Superfamily
C5I45_RS07545	COG0768	penicillin binding
C5I45_RS07550	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C5I45_RS07555	COG0573	inorganic phosphate transmembrane transporter activity
C5I45_RS07560	COG0581	inorganic phosphate transmembrane transporter activity
C5I45_RS07565	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C5I45_RS07570	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C5I45_RS07575	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C5I45_RS07590	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C5I45_RS07600	COG1757	Na H antiporter
C5I45_RS07605	COG4483	Protein conserved in bacteria
C5I45_RS07610	COG1940	carbohydrate kinase activity
C5I45_RS07615	COG2866	Carboxypeptidase
C5I45_RS07625	COG0011	TIGRFAM Protein of
C5I45_RS07635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C5I45_RS07645	COG1393	Belongs to the ArsC family
C5I45_RS07655	COG1366	Belongs to the anti-sigma-factor antagonist family
C5I45_RS07660	COG1253	flavin adenine dinucleotide binding
C5I45_RS07665	COG0598	Magnesium transport protein CorA
C5I45_RS07670	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C5I45_RS07675	COG1459	type II secretion system
C5I45_RS07680	COG4537	Required for transformation and DNA binding
C5I45_RS07685	COG4970	Tfp pilus assembly protein FimT
C5I45_RS07695	COG4940	Competence protein ComGF
C5I45_RS07720	COG0681	Belongs to the peptidase S26 family
C5I45_RS07730	COG1396	sequence-specific DNA binding
C5I45_RS07745	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C5I45_RS07765	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C5I45_RS07780	COG1752	Esterase of the alpha-beta hydrolase superfamily
C5I45_RS07790	COG3872	metal-dependent enzyme
C5I45_RS07800	COG0006	proline dipeptidase activity
C5I45_RS07815	COG3854	ATPases associated with a variety of cellular activities
C5I45_RS07855	COG0511	ligase activity, forming carbon-carbon bonds
C5I45_RS07860	COG0439	Biotin carboxylase
C5I45_RS07865	COG1302	Protein conserved in bacteria
C5I45_RS07880	COG1570	exodeoxyribonuclease VII activity
C5I45_RS07890	COG0142	geranyltranstransferase activity
C5I45_RS07900	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
C5I45_RS07910	COG0497	DNA recombination
C5I45_RS07915	COG0750	zinc metalloprotease
C5I45_RS07920	COG0745	RESPONSE REGULATOR receiver
C5I45_RS07930	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C5I45_RS07945	COG1902	pentaerythritol trinitrate reductase activity
C5I45_RS07965	COG0860	N-Acetylmuramoyl-L-alanine amidase
C5I45_RS07970	COG0584	glycerophosphoryl diester phosphodiesterase
C5I45_RS07975	COG0183	Belongs to the thiolase family
C5I45_RS07980	COG1250	3-hydroxyacyl-CoA dehydrogenase
C5I45_RS07985	COG1960	acyl-CoA dehydrogenase activity
C5I45_RS07990	COG0372	Belongs to the citrate synthase family
C5I45_RS07995	COG2079	MmgE PrpD family protein
C5I45_RS08000	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C5I45_RS08010	COG3290	protein histidine kinase activity
C5I45_RS08010	COG3829	transcription factor binding
C5I45_RS08015	COG0280	phosphate acetyltransferase
C5I45_RS08020	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C5I45_RS08025	COG3426	butyrate kinase activity
C5I45_RS08030	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C5I45_RS08035	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C5I45_RS08040	COG0022	dehydrogenase e1 component
C5I45_RS08045	COG0508	dehydrogenase complex catalyzes the overall conversion of
C5I45_RS08050	COG1597	lipid kinase activity
C5I45_RS08060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5I45_RS08065	COG0765	amino acid transport
C5I45_RS08070	COG1126	abc transporter atp-binding protein
C5I45_RS08075	COG4129	membrane
C5I45_RS08080	COG1376	ErfK ybiS ycfS ynhG family protein
C5I45_RS08085	COG0346	lactoylglutathione lyase activity
C5I45_RS08090	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C5I45_RS08095	COG2195	Cleaves the N-terminal amino acid of tripeptides
C5I45_RS08100	COG0706	membrane insertase activity
C5I45_RS08115	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C5I45_RS08120	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C5I45_RS08135	COG0596	Alpha beta hydrolase
C5I45_RS08160	COG0250	Participates in transcription elongation, termination and antitermination
C5I45_RS08170	COG2070	2-Nitropropane dioxygenase
C5I45_RS08170	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C5I45_RS08185	COG0318	PFAM AMP-dependent synthetase and ligase
C5I45_RS08190	COG1028	Short-chain dehydrogenase reductase Sdr
C5I45_RS08195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C5I45_RS08195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C5I45_RS08195	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C5I45_RS08195	COG1028	Short-chain dehydrogenase reductase Sdr
C5I45_RS08195	COG3321	synthase
C5I45_RS08200	COG0300	oxidoreductase activity
C5I45_RS08200	COG3321	synthase
C5I45_RS08200	COG1028	Short-chain dehydrogenase reductase Sdr
C5I45_RS08200	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C5I45_RS08200	COG0318	PFAM AMP-dependent synthetase and ligase
C5I45_RS08205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C5I45_RS08205	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C5I45_RS08205	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C5I45_RS08205	COG1028	Short-chain dehydrogenase reductase Sdr
C5I45_RS08205	COG3321	synthase
C5I45_RS08210	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C5I45_RS08210	COG0318	PFAM AMP-dependent synthetase and ligase
C5I45_RS08210	COG3321	synthase
C5I45_RS08210	COG0300	oxidoreductase activity
C5I45_RS08210	COG1028	Short-chain dehydrogenase reductase Sdr
C5I45_RS08215	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C5I45_RS08215	COG1028	Short-chain dehydrogenase reductase Sdr
C5I45_RS08215	COG3321	synthase
C5I45_RS08215	COG0300	oxidoreductase activity
C5I45_RS08215	COG0318	PFAM AMP-dependent synthetase and ligase
C5I45_RS08220	COG3321	synthase
C5I45_RS08220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C5I45_RS08220	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C5I45_RS08220	COG1028	Short-chain dehydrogenase reductase Sdr
C5I45_RS08220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C5I45_RS08225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C5I45_RS08225	COG1028	Short-chain dehydrogenase reductase Sdr
C5I45_RS08225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C5I45_RS08225	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C5I45_RS08225	COG3321	synthase
C5I45_RS08230	COG2124	cytochrome p450
C5I45_RS08235	COG3425	synthase
C5I45_RS08240	COG1024	Enoyl-CoA hydratase
C5I45_RS08245	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C5I45_RS08250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C5I45_RS08255	COG0300	oxidoreductase activity
C5I45_RS08260	COG3048	D-serine ammonia-lyase activity
C5I45_RS08270	COG0346	lactoylglutathione lyase activity
C5I45_RS08280	COG0628	permease
C5I45_RS08295	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C5I45_RS08300	COG0456	acetyltransferase
C5I45_RS08305	COG2329	Antibiotic biosynthesis monooxygenase
C5I45_RS08310	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C5I45_RS08310	COG0456	acetyltransferase
C5I45_RS08315	COG4918	Iron-sulphur cluster biosynthesis
C5I45_RS08325	COG1073	alpha beta
C5I45_RS08335	COG0667	Aldo Keto reductase
C5I45_RS08345	COG0494	nUDIX hydrolase
C5I45_RS08350	COG1379	DNA repair
C5I45_RS08355	COG1396	sequence-specific DNA binding
C5I45_RS08360	COG0252	asparaginase activity
C5I45_RS08365	COG1027	Aspartate ammonia-lyase
C5I45_RS08370	COG1757	Na H antiporter
C5I45_RS08375	COG0281	malic enzyme
C5I45_RS08390	COG1300	Membrane
C5I45_RS08395	COG0735	belongs to the Fur family
C5I45_RS08405	COG4974	Belongs to the 'phage' integrase family
C5I45_RS08410	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
C5I45_RS08415	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
C5I45_RS08420	COG1686	Belongs to the peptidase S11 family
C5I45_RS08425	COG1366	Belongs to the anti-sigma-factor antagonist family
C5I45_RS08435	COG1191	sigma factor activity
C5I45_RS08455	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C5I45_RS08470	COG0697	spore germination
C5I45_RS08475	COG0019	diaminopimelate decarboxylase activity
C5I45_RS08480	COG4086	secreted protein
C5I45_RS08485	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C5I45_RS08495	COG0681	Belongs to the peptidase S26 family
C5I45_RS08505	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C5I45_RS08505	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C5I45_RS08510	COG0307	riboflavin synthase, alpha
C5I45_RS08525	COG0456	acetyltransferase
C5I45_RS08535	COG1547	Domain of unknown function (DUF309)
C5I45_RS08560	COG1686	Belongs to the peptidase S11 family
C5I45_RS08565	COG2715	membrane protein required for spore maturation
C5I45_RS08570	COG0700	Nucleoside recognition
C5I45_RS08575	COG1187	pseudouridine synthase activity
C5I45_RS08580	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C5I45_RS08585	COG1333	cytochrome c biogenesis protein
C5I45_RS08590	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C5I45_RS08595	COG0745	RESPONSE REGULATOR receiver
C5I45_RS08600	COG5002	protein histidine kinase activity
C5I45_RS08605	COG1595	DNA-templated transcription, initiation
C5I45_RS08615	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C5I45_RS08620	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
C5I45_RS08625	COG1141	Ferredoxin
C5I45_RS08630	COG4955	Helix-turn-helix domain
C5I45_RS08635	COG0514	ATP-dependent DNA helicase (RecQ)
C5I45_RS08640	COG1266	CAAX protease self-immunity
C5I45_RS08645	COG1388	LysM domain
C5I45_RS08655	COG1408	metallophosphoesterase
C5I45_RS08660	COG4862	establishment of competence for transformation
C5I45_RS08665	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C5I45_RS08670	COG0492	ferredoxin-NADP+ reductase activity
C5I45_RS08675	COG2339	peptidase activity
C5I45_RS08680	COG3773	Cell wall hydrolase
C5I45_RS08680	COG3409	Peptidoglycan-binding domain 1 protein
C5I45_RS08685	COG2959	enzyme of heme biosynthesis
C5I45_RS08690	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
C5I45_RS08700	COG0539	negative regulation of cytoplasmic translation
C5I45_RS08740	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C5I45_RS08745	COG0776	regulation of translation
C5I45_RS08760	COG0142	geranyltranstransferase activity
C5I45_RS08770	COG0142	geranyltranstransferase activity
C5I45_RS08775	COG0105	UTP biosynthetic process
C5I45_RS08780	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C5I45_RS08795	COG4401	Chorismate mutase type I
C5I45_RS08800	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C5I45_RS08835	COG0287	Prephenate dehydrogenase
C5I45_RS08845	COG0457	Tetratricopeptide repeat
C5I45_RS08860	COG0723	plastoquinol--plastocyanin reductase activity
C5I45_RS08865	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C5I45_RS08870	COG2010	Cytochrome c
C5I45_RS08870	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C5I45_RS08875	COG4347	Protein of unknown function (DUF1405)
C5I45_RS08885	COG2140	Oxalate decarboxylase
C5I45_RS08890	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C5I45_RS08895	COG1694	Mazg nucleotide pyrophosphohydrolase
C5I45_RS08910	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C5I45_RS08915	COG0438	transferase activity, transferring glycosyl groups
C5I45_RS08945	COG1199	ATP-dependent helicase activity
C5I45_RS08945	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C5I45_RS08955	COG5353	protein conserved in bacteria
C5I45_RS08960	COG0436	Aminotransferase
C5I45_RS08970	COG3935	DnaD domain protein
C5I45_RS08975	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C5I45_RS08985	COG4499	WXG100 protein secretion system (Wss), protein YukC
C5I45_RS08985	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C5I45_RS09025	COG0071	Belongs to the small heat shock protein (HSP20) family
C5I45_RS09030	COG2190	(PTS) system
C5I45_RS09035	COG1111	helicase
C5I45_RS09035	COG1205	dead DEAH box helicase
C5I45_RS09040	COG3359	exonuclease
C5I45_RS09065	COG0116	Belongs to the methyltransferase superfamily
C5I45_RS09080	COG1199	ATP-dependent helicase activity
C5I45_RS09085	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
C5I45_RS09095	COG2233	PERMEase
C5I45_RS09105	COG1335	isochorismatase
C5I45_RS09130	COG3424	synthase
C5I45_RS09135	COG1755	Isoprenylcysteine carboxyl methyltransferase
C5I45_RS09145	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C5I45_RS09160	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C5I45_RS09170	COG0328	RNA-DNA hybrid ribonuclease activity
C5I45_RS09175	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C5I45_RS09180	COG0328	RNA-DNA hybrid ribonuclease activity
C5I45_RS09200	COG1278	Cold shock
C5I45_RS09205	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C5I45_RS09215	COG0386	Belongs to the glutathione peroxidase family
C5I45_RS09220	COG1418	mRNA catabolic process
C5I45_RS09225	COG1413	lyase activity
C5I45_RS09240	COG2521	methyltransferase
C5I45_RS09240	COG2136	Putative SAM-dependent methyltransferase
C5I45_RS09255	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C5I45_RS09260	COG0204	Acyl-transferase
C5I45_RS09265	COG1272	protein, Hemolysin III
C5I45_RS09270	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C5I45_RS09275	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C5I45_RS09285	COG1999	signal sequence binding
C5I45_RS09290	COG2755	lipolytic protein G-D-S-L family
C5I45_RS09295	COG4698	Protein conserved in bacteria
C5I45_RS09300	COG1846	Transcriptional regulator
C5I45_RS09320	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C5I45_RS09340	COG1525	nuclease
C5I45_RS09345	COG4282	regulation of fungal-type cell wall biogenesis
C5I45_RS09350	COG5444	nuclease activity
C5I45_RS09395	COG0457	Tetratricopeptide repeat
C5I45_RS09400	COG1388	LysM domain
C5I45_RS09415	COG1793	dna ligase
C5I45_RS09455	COG1086	Polysaccharide biosynthesis protein
C5I45_RS09465	COG4641	Protein conserved in bacteria
C5I45_RS09480	COG0463	Glycosyl transferase, family 2
C5I45_RS09485	COG0456	acetyltransferase
C5I45_RS09495	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
C5I45_RS09500	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C5I45_RS09505	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C5I45_RS09510	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C5I45_RS09515	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C5I45_RS09520	COG0456	acetyltransferase
C5I45_RS09525	COG1509	lysine 2,3-aminomutase activity
C5I45_RS09560	COG0671	phosphoesterase, PA-phosphatase related
C5I45_RS09580	COG1876	peptidase activity
C5I45_RS09590	COG2226	methyltransferase
C5I45_RS09595	COG3409	Peptidoglycan-binding domain 1 protein
C5I45_RS09595	COG0793	Belongs to the peptidase S41A family
C5I45_RS09600	COG2188	Transcriptional regulator
C5I45_RS09605	COG2723	6-phospho-beta-galactosidase activity
C5I45_RS09615	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C5I45_RS09625	COG0346	lactoylglutathione lyase activity
C5I45_RS09630	COG0400	carboxylic ester hydrolase activity
C5I45_RS09635	COG0778	Nitroreductase
C5I45_RS09640	COG1733	regulation of RNA biosynthetic process
C5I45_RS09650	COG1942	4-Oxalocrotonate Tautomerase
C5I45_RS09665	COG2962	Rard protein
C5I45_RS09675	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C5I45_RS09680	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C5I45_RS09685	COG1366	Belongs to the anti-sigma-factor antagonist family
C5I45_RS09690	COG0534	Mate efflux family protein
C5I45_RS09695	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C5I45_RS09700	COG1819	glycosyl
C5I45_RS09705	COG1388	LysM domain
C5I45_RS09705	COG0791	NLP P60 protein
C5I45_RS09710	COG2032	superoxide dismutase activity
C5I45_RS09715	COG0714	Associated with various cellular activities
C5I45_RS09720	COG4548	von Willebrand factor, type A
C5I45_RS09730	COG0508	dehydrogenase complex catalyzes the overall conversion of
C5I45_RS09735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C5I45_RS09740	COG0385	Bile acid
C5I45_RS09745	COG0733	neurotransmitter:sodium symporter activity
C5I45_RS09750	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C5I45_RS09755	COG1657	PFAM Prenyltransferase squalene oxidase
C5I45_RS09760	COG1012	belongs to the aldehyde dehydrogenase family
C5I45_RS09790	COG0071	Belongs to the small heat shock protein (HSP20) family
C5I45_RS09805	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C5I45_RS09810	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C5I45_RS09820	COG0514	ATP-dependent DNA helicase (RecQ)
C5I45_RS09825	COG1388	LysM domain
C5I45_RS09825	COG3584	3D domain protein
C5I45_RS09835	COG1619	proteins homologs of microcin C7 resistance protein MccF
C5I45_RS09850	COG2322	membrane
C5I45_RS09855	COG0741	lytic transglycosylase activity
C5I45_RS09860	COG0640	Transcriptional regulator
C5I45_RS09870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C5I45_RS09875	COG1309	transcriptional regulator
C5I45_RS09880	COG2207	Transcriptional regulator
C5I45_RS09880	COG0662	Cupin 2, conserved barrel domain protein
C5I45_RS09885	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C5I45_RS09890	COG1733	regulation of RNA biosynthetic process
C5I45_RS09895	COG1028	Short-chain dehydrogenase reductase Sdr
C5I45_RS09930	COG3220	belongs to the UPF0276 family
C5I45_RS10015	COG0243	molybdopterin cofactor binding
C5I45_RS10020	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C5I45_RS10025	COG1070	Carbohydrate kinase
C5I45_RS10030	COG2814	Major facilitator Superfamily
C5I45_RS10040	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
C5I45_RS10045	COG0300	oxidoreductase activity
C5I45_RS10060	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C5I45_RS10065	COG0583	DNA-binding transcription factor activity
C5I45_RS10070	COG0069	glutamate synthase activity
C5I45_RS10070	COG0067	glutamate synthase
C5I45_RS10070	COG0070	glutamate synthase
C5I45_RS10075	COG0493	'glutamate synthase
C5I45_RS10085	COG0604	alcohol dehydrogenase
C5I45_RS10100	COG0640	Transcriptional regulator
C5I45_RS10105	COG2814	Major facilitator Superfamily
C5I45_RS10110	COG0405	Gamma-glutamyltransferase
C5I45_RS10115	COG0166	Belongs to the GPI family
C5I45_RS10120	COG0582	viral genome integration into host DNA
C5I45_RS10135	COG0534	Mate efflux family protein
C5I45_RS10140	COG2017	converts alpha-aldose to the beta-anomer
C5I45_RS10145	COG2027	D-alanyl-D-alanine carboxypeptidase
C5I45_RS10160	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C5I45_RS10170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C5I45_RS10175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C5I45_RS10175	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
C5I45_RS10185	COG1649	PFAM Uncharacterised BCR, COG1649
C5I45_RS10190	COG1960	acyl-CoA dehydrogenase activity
C5I45_RS10195	COG0318	PFAM AMP-dependent synthetase and ligase
C5I45_RS10200	COG0439	Biotin carboxylase
C5I45_RS10205	COG0511	ligase activity, forming carbon-carbon bonds
C5I45_RS10210	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C5I45_RS10215	COG1024	Enoyl-CoA hydratase
C5I45_RS10220	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C5I45_RS10225	COG0586	Pfam SNARE associated Golgi protein
C5I45_RS10230	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C5I45_RS10235	COG2246	polysaccharide biosynthetic process
C5I45_RS10245	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C5I45_RS10265	COG2124	cytochrome p450
C5I45_RS10270	COG2610	gluconate transmembrane transporter activity
C5I45_RS10275	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C5I45_RS10280	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C5I45_RS10285	COG1028	Short-chain dehydrogenase reductase Sdr
C5I45_RS10315	COG3507	Belongs to the glycosyl hydrolase 43 family
C5I45_RS10325	COG0745	RESPONSE REGULATOR receiver
C5I45_RS10330	COG2205	protein histidine kinase activity
C5I45_RS10380	COG2271	Major facilitator Superfamily
C5I45_RS10385	COG1609	Transcriptional regulator
C5I45_RS10390	COG1028	Short-chain dehydrogenase reductase Sdr
C5I45_RS10395	COG1312	Catalyzes the dehydration of D-mannonate
C5I45_RS10400	COG0800	Aldolase
C5I45_RS10405	COG1063	alcohol dehydrogenase
C5I45_RS10415	COG1115	amino acid carrier protein
C5I45_RS10425	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C5I45_RS10430	COG0187	DNA topoisomerase II activity
C5I45_RS10435	COG1832	CoA-binding protein
C5I45_RS10445	COG4841	protein insertion into membrane
C5I45_RS10455	COG0824	Thioesterase
C5I45_RS10475	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C5I45_RS10480	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C5I45_RS10495	COG0071	Belongs to the small heat shock protein (HSP20) family
C5I45_RS10505	COG4846	Membrane protein involved in cytochrome C biogenesis
C5I45_RS10510	COG2201	protein-glutamate methylesterase activity
C5I45_RS10515	COG0785	Cytochrome C biogenesis protein
C5I45_RS10535	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C5I45_RS10545	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C5I45_RS10575	COG4195	phage-related replication protein
C5I45_RS10580	COG0756	dUTP diphosphatase activity
C5I45_RS10590	COG5434	Belongs to the glycosyl hydrolase 28 family
C5I45_RS10605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C5I45_RS10615	COG3397	chitin binding
C5I45_RS10665	COG1064	alcohol dehydrogenase
C5I45_RS10670	COG2318	DinB family
C5I45_RS10675	COG2378	regulation of single-species biofilm formation
C5I45_RS10695	COG3848	Pyruvate phosphate dikinase
C5I45_RS10695	COG0574	Belongs to the PEP-utilizing enzyme family
C5I45_RS10700	COG1070	Carbohydrate kinase
C5I45_RS10715	COG3507	Belongs to the glycosyl hydrolase 43 family
C5I45_RS10720	COG2211	Major facilitator Superfamily
C5I45_RS10770	COG0174	glutamine synthetase
C5I45_RS10775	COG0789	Transcriptional regulator
C5I45_RS10780	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
C5I45_RS10785	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C5I45_RS10790	COG0464	growth
C5I45_RS10800	COG0860	N-Acetylmuramoyl-L-alanine amidase
C5I45_RS10805	COG4112	unkown
C5I45_RS10810	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C5I45_RS10815	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C5I45_RS10855	COG2076	Multidrug Resistance protein
C5I45_RS10865	COG1764	response to oxidative stress
C5I45_RS10870	COG4195	phage-related replication protein
C5I45_RS10880	COG1404	Belongs to the peptidase S8 family
C5I45_RS10890	COG3619	membrane
C5I45_RS10895	COG3209	COG3209 Rhs family protein
C5I45_RS10900	COG2124	cytochrome p450
C5I45_RS10905	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C5I45_RS10905	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C5I45_RS10905	COG3321	synthase
C5I45_RS10905	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
C5I45_RS10910	COG4221	oxidoreductase activity
C5I45_RS10910	COG3321	synthase
C5I45_RS10910	COG1028	Short-chain dehydrogenase reductase Sdr
C5I45_RS10910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C5I45_RS10915	COG1028	Short-chain dehydrogenase reductase Sdr
C5I45_RS10915	COG3321	synthase
C5I45_RS10915	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C5I45_RS10915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C5I45_RS10915	COG1028	Short-chain dehydrogenase reductase Sdr
C5I45_RS10915	COG3321	synthase
C5I45_RS10915	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C5I45_RS10915	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C5I45_RS10915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C5I45_RS10915	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C5I45_RS10920	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C5I45_RS10920	COG3321	synthase
C5I45_RS10920	COG4221	oxidoreductase activity
C5I45_RS10920	COG0300	oxidoreductase activity
C5I45_RS10925	COG1028	Short-chain dehydrogenase reductase Sdr
C5I45_RS10925	COG3321	synthase
C5I45_RS10925	COG0318	PFAM AMP-dependent synthetase and ligase
C5I45_RS10925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C5I45_RS10925	COG0300	oxidoreductase activity
C5I45_RS10930	COG1024	Enoyl-CoA hydratase
C5I45_RS10935	COG1024	Enoyl-CoA hydratase
C5I45_RS10940	COG3425	synthase
C5I45_RS10945	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C5I45_RS10995	COG4550	Control of competence regulator ComK, YlbF/YmcA
C5I45_RS11015	COG2359	stage V sporulation protein S
C5I45_RS11020	COG1692	metallophosphoesterase
C5I45_RS11030	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C5I45_RS11045	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C5I45_RS11050	COG1426	Protein conserved in bacteria
C5I45_RS11065	COG0300	oxidoreductase activity
C5I45_RS11070	COG0612	Peptidase, M16
C5I45_RS11075	COG0612	Peptidase, M16
C5I45_RS11080	COG2409	Drug exporters of the RND superfamily
C5I45_RS11080	COG1033	growth of symbiont in host cell
C5I45_RS11085	COG1846	Transcriptional regulator
C5I45_RS11090	COG2814	Major facilitator Superfamily
C5I45_RS11095	COG2188	Transcriptional regulator
C5I45_RS11100	COG4980	gas vesicle protein
C5I45_RS11100	COG1674	ftsk spoiiie
C5I45_RS11110	COG0740	serine-type endopeptidase activity
C5I45_RS11115	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C5I45_RS11125	COG0527	aspartate kinase activity
C5I45_RS11130	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C5I45_RS11135	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C5I45_RS11140	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C5I45_RS11145	COG1873	PFAM PRC-barrel domain
C5I45_RS11150	COG0612	Peptidase, M16
C5I45_RS11155	COG0726	polysaccharide deacetylase
C5I45_RS11170	COG0196	riboflavin kinase activity
C5I45_RS11185	COG1550	Protein conserved in bacteria
C5I45_RS11195	COG1358	cellular component organization or biogenesis
C5I45_RS11200	COG2740	Nucleic-acid-binding protein implicated in transcription termination
C5I45_RS11205	COG0195	Participates in both transcription termination and antitermination
C5I45_RS11215	COG2176	DNA-directed DNA polymerase activity
C5I45_RS11225	COG0750	zinc metalloprotease
C5I45_RS11235	COG4589	Belongs to the CDS family
C5I45_RS11240	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C5I45_RS11270	COG1191	sigma factor activity
C5I45_RS11280	COG1776	CheC inhibitor of MCP methylation
C5I45_RS11285	COG0835	chemotaxis
C5I45_RS11290	COG0643	Histidine kinase
C5I45_RS11290	COG2198	Histidine kinase
C5I45_RS11295	COG2201	protein-glutamate methylesterase activity
C5I45_RS11300	COG0455	bacterial-type flagellum organization
C5I45_RS11305	COG1419	protein localization to endoplasmic reticulum
C5I45_RS11310	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C5I45_RS11315	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C5I45_RS11320	COG1684	flagellar biosynthetic protein fliR
C5I45_RS11325	COG1987	bacterial-type flagellum assembly
C5I45_RS11330	COG1338	Plays a role in the flagellum-specific transport system
C5I45_RS11335	COG3190	flagellar
C5I45_RS11340	COG2201	protein-glutamate methylesterase activity
C5I45_RS11345	COG1776	CheC inhibitor of MCP methylation
C5I45_RS11345	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C5I45_RS11350	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C5I45_RS11355	COG1580	Controls the rotational direction of flagella during chemotaxis
C5I45_RS11360	COG1582	Flagellar protein (FlbD)
C5I45_RS11365	COG4786	Flagellar basal body rod
C5I45_RS11370	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C5I45_RS11375	COG3144	bacterial-type flagellum assembly
C5I45_RS11380	COG3334	PFAM MgtE intracellular
C5I45_RS11385	COG2882	bacterial-type flagellum organization
C5I45_RS11390	COG1157	protein secretion by the type III secretion system
C5I45_RS11395	COG1317	bacterial-type flagellum organization
C5I45_RS11400	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C5I45_RS11405	COG1766	The M ring may be actively involved in energy transduction
C5I45_RS11410	COG1677	Flagellar hook-basal body complex protein FliE
C5I45_RS11415	COG1558	bacterial-type flagellum-dependent cell motility
C5I45_RS11420	COG1815	bacterial-type flagellum-dependent cell motility
C5I45_RS11440	COG4974	Belongs to the 'phage' integrase family
C5I45_RS11450	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C5I45_RS11455	COG0758	DNA mediated transformation
C5I45_RS11460	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C5I45_RS11470	COG2257	FlhB HrpN YscU SpaS Family
C5I45_RS11485	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C5I45_RS11510	COG1837	Belongs to the UPF0109 family
C5I45_RS11520	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C5I45_RS11535	COG0552	protein localization to endoplasmic reticulum
C5I45_RS11540	COG1196	nuclear chromosome segregation
C5I45_RS11555	COG1028	Short-chain dehydrogenase reductase Sdr
C5I45_RS11560	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C5I45_RS11575	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C5I45_RS11580	COG1760	l-serine dehydratase
C5I45_RS11585	COG1760	l-serine dehydratase
C5I45_RS11590	COG1461	Dihydroxyacetone kinase
C5I45_RS11595	COG1302	Protein conserved in bacteria
C5I45_RS11610	COG1564	THIamine pyrophosphokinase
C5I45_RS11615	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C5I45_RS11625	COG2815	serine threonine protein kinase
C5I45_RS11625	COG0515	serine threonine protein kinase
C5I45_RS11630	COG0631	protein serine/threonine phosphatase activity
C5I45_RS11640	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C5I45_RS11640	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C5I45_RS11650	COG0242	peptide deformylase activity
C5I45_RS11655	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C5I45_RS11660	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C5I45_RS11670	COG0194	GDP metabolic process
C5I45_RS11680	COG1561	YicC-like family, N-terminal region
C5I45_RS11685	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C5I45_RS11700	COG1648	precorrin-2 dehydrogenase activity
C5I45_RS11705	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
C5I45_RS11710	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C5I45_RS11725	COG0306	phosphate transporter
C5I45_RS11735	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C5I45_RS11740	COG0284	orotidine-5'-phosphate decarboxylase activity
C5I45_RS11755	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C5I45_RS11760	COG0505	Belongs to the CarA family
C5I45_RS11765	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C5I45_RS11775	COG2233	PERMEase
C5I45_RS11785	COG0564	pseudouridine synthase activity
C5I45_RS11795	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C5I45_RS11800	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C5I45_RS11810	COG3599	regulation of cell shape
C5I45_RS11815	COG2302	S4 RNA-binding domain
C5I45_RS11820	COG0762	integral membrane protein
C5I45_RS11830	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C5I45_RS11835	COG1496	oxidoreductase activity
C5I45_RS11840	COG1873	PFAM PRC-barrel domain
C5I45_RS11845	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C5I45_RS11850	COG1119	ATPase activity
C5I45_RS11855	COG1191	sigma factor activity
C5I45_RS11860	COG1191	sigma factor activity
C5I45_RS11870	COG1404	Belongs to the peptidase S8 family
C5I45_RS11870	COG4412	M6 family metalloprotease domain protein
C5I45_RS11875	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C5I45_RS11880	COG0849	cell division
C5I45_RS11885	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C5I45_RS11900	COG0772	Belongs to the SEDS family
C5I45_RS11920	COG0768	penicillin binding
C5I45_RS11925	COG0768	penicillin binding
C5I45_RS11930	COG4839	cell division protein FtsL
C5I45_RS11950	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C5I45_RS11970	COG1399	metal-binding, possibly nucleic acid-binding protein
C5I45_RS11980	COG3480	Lon protease (S16) C-terminal proteolytic domain
C5I45_RS11985	COG1752	Esterase of the alpha-beta hydrolase superfamily
C5I45_RS11990	COG3314	Sporulation integral membrane protein YlbJ
C5I45_RS12000	COG0742	ribosomal rna small subunit methyltransferase
C5I45_RS12015	COG3679	Belongs to the UPF0342 family
C5I45_RS12030	COG2340	Cysteine-rich secretory protein family
C5I45_RS12035	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
C5I45_RS12045	COG3336	cytochrome c oxidase
C5I45_RS12050	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C5I45_RS12055	COG1845	cytochrome c oxidase, subunit III
C5I45_RS12060	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C5I45_RS12065	COG2010	Cytochrome c
C5I45_RS12065	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C5I45_RS12080	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
C5I45_RS12085	COG0772	Belongs to the SEDS family
C5I45_RS12095	COG2066	Belongs to the glutaminase family
C5I45_RS12100	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C5I45_RS12105	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C5I45_RS12115	COG4896	Protein conserved in bacteria
C5I45_RS12125	COG1217	gtp-binding protein TYPA
C5I45_RS12150	COG3227	Zinc metalloprotease (Elastase)
C5I45_RS12160	COG0483	inositol monophosphate 1-phosphatase activity
C5I45_RS12190	COG1982	Orn Lys Arg decarboxylase major
C5I45_RS12205	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C5I45_RS12210	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C5I45_RS12215	COG0508	dehydrogenase complex catalyzes the overall conversion of
C5I45_RS12220	COG0022	dehydrogenase e1 component
C5I45_RS12225	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C5I45_RS12230	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C5I45_RS12235	COG1028	Short-chain dehydrogenase reductase Sdr
C5I45_RS12235	COG3321	synthase
C5I45_RS12235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C5I45_RS12235	COG4221	oxidoreductase activity
C5I45_RS12240	COG0300	oxidoreductase activity
C5I45_RS12240	COG4221	oxidoreductase activity
C5I45_RS12240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C5I45_RS12240	COG3321	synthase
C5I45_RS12245	COG3321	synthase
C5I45_RS12245	COG4221	oxidoreductase activity
C5I45_RS12245	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C5I45_RS12245	COG0300	oxidoreductase activity
C5I45_RS12250	COG4221	oxidoreductase activity
C5I45_RS12250	COG0300	oxidoreductase activity
C5I45_RS12250	COG3321	synthase
C5I45_RS12250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C5I45_RS12255	COG3321	synthase
C5I45_RS12255	COG1028	Short-chain dehydrogenase reductase Sdr
C5I45_RS12255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C5I45_RS12255	COG4221	oxidoreductase activity
C5I45_RS12260	COG0300	oxidoreductase activity
C5I45_RS12260	COG3321	synthase
C5I45_RS12260	COG4221	oxidoreductase activity
C5I45_RS12260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C5I45_RS12265	COG3321	synthase
C5I45_RS12265	COG4221	oxidoreductase activity
C5I45_RS12265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C5I45_RS12265	COG1028	Short-chain dehydrogenase reductase Sdr
C5I45_RS12280	COG0497	DNA recombination
C5I45_RS12290	COG0242	peptide deformylase activity
C5I45_RS12295	COG0561	phosphatase activity
C5I45_RS12310	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C5I45_RS12320	COG0569	domain protein
C5I45_RS12325	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
C5I45_RS12325	COG2105	PFAM AIG2 family protein
C5I45_RS12330	COG3852	Histidine kinase
C5I45_RS12335	COG2002	toxin-antitoxin pair type II binding
C5I45_RS12345	COG1077	Cell shape determining protein MreB Mrl
C5I45_RS12355	COG2309	aminopeptidase activity
C5I45_RS12360	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C5I45_RS12365	COG0488	(ABC) transporter
C5I45_RS12375	COG0681	Belongs to the peptidase S26 family
C5I45_RS12380	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C5I45_RS12380	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5I45_RS12380	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C5I45_RS12385	COG1105	Belongs to the carbohydrate kinase PfkB family
C5I45_RS12390	COG1349	DNA-binding transcription factor activity
C5I45_RS12395	COG0577	efflux transmembrane transporter activity
C5I45_RS12400	COG1136	(ABC) transporter
C5I45_RS12405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C5I45_RS12415	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C5I45_RS12420	COG0314	molybdopterin synthase activity
C5I45_RS12425	COG1763	Mo-molybdopterin cofactor biosynthetic process
C5I45_RS12430	COG0303	'Molybdopterin
C5I45_RS12435	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C5I45_RS12455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C5I45_RS12460	COG0668	transmembrane transport
C5I45_RS12480	COG0716	FMN binding
C5I45_RS12490	COG0716	FMN binding
C5I45_RS12495	COG0583	DNA-binding transcription factor activity
C5I45_RS12500	COG0517	IMP dehydrogenase activity
C5I45_RS12510	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
C5I45_RS12515	COG4703	Protein of unknown function (DUF1797)
C5I45_RS12520	COG2200	EAL domain
C5I45_RS12535	COG1028	Short-chain dehydrogenase reductase Sdr
C5I45_RS12540	COG1408	metallophosphoesterase
C5I45_RS12545	COG1376	ErfK ybiS ycfS ynhG family protein
C5I45_RS12550	COG2814	Major facilitator Superfamily
C5I45_RS12560	COG0784	Response regulator, receiver
C5I45_RS12560	COG0835	chemotaxis
C5I45_RS12570	COG0436	Aminotransferase
C5I45_RS12575	COG4191	Histidine kinase
C5I45_RS12580	COG0768	penicillin binding
C5I45_RS12585	COG2340	Cysteine-rich secretory protein family
C5I45_RS12590	COG2084	Dehydrogenase
C5I45_RS12595	COG0840	transmembrane signaling receptor activity
C5I45_RS12600	COG1533	DNA photolyase activity
C5I45_RS12610	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C5I45_RS12615	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5I45_RS12620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C5I45_RS12620	COG1263	PTS System
C5I45_RS12620	COG2190	(PTS) system
C5I45_RS12625	COG3711	transcriptional antiterminator
C5I45_RS12630	COG1609	Transcriptional regulator
C5I45_RS12635	COG0006	proline dipeptidase activity
C5I45_RS12640	COG2217	Heavy metal translocating P-type atpase
C5I45_RS12645	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C5I45_RS12650	COG2244	polysaccharide biosynthetic process
C5I45_RS12655	COG3773	Cell wall hydrolase
C5I45_RS12665	COG4873	Protein conserved in bacteria
C5I45_RS12680	COG0602	queuosine metabolic process
C5I45_RS12685	COG0720	synthase
C5I45_RS12700	COG3949	Membrane
C5I45_RS12710	COG0542	response to heat
C5I45_RS12715	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C5I45_RS12720	COG1360	Flagellar Motor Protein
C5I45_RS12725	COG1846	Transcriptional regulator
C5I45_RS12730	COG3852	Histidine kinase
C5I45_RS12760	COG0436	Aminotransferase
C5I45_RS12765	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C5I45_RS12780	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C5I45_RS12785	COG5002	protein histidine kinase activity
C5I45_RS12790	COG3594	Acyltransferase
C5I45_RS12800	COG2323	membrane
C5I45_RS12805	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C5I45_RS12830	COG1191	sigma factor activity
C5I45_RS12835	COG0861	Integral membrane protein TerC family
C5I45_RS12840	COG0586	Pfam SNARE associated Golgi protein
C5I45_RS12850	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
C5I45_RS12855	COG1793	dna ligase
C5I45_RS12855	COG3285	dna ligase
C5I45_RS12860	COG0726	polysaccharide deacetylase
C5I45_RS12865	COG1846	Transcriptional regulator
C5I45_RS12880	COG0789	Transcriptional regulator
C5I45_RS12885	COG2239	Acts as a magnesium transporter
C5I45_RS12905	COG1388	LysM domain
C5I45_RS12905	COG3858	chitin binding
C5I45_RS12910	COG4721	ABC-type cobalt transport system, permease component
C5I45_RS12915	COG1122	ATPase activity
C5I45_RS12920	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C5I45_RS12925	COG1366	Belongs to the anti-sigma-factor antagonist family
C5I45_RS12930	COG1404	Belongs to the peptidase S8 family
C5I45_RS12940	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C5I45_RS12945	COG2814	Major facilitator Superfamily
C5I45_RS12955	COG0463	Glycosyl transferase, family 2
C5I45_RS12955	COG0457	Tetratricopeptide repeat
C5I45_RS12970	COG1764	response to oxidative stress
C5I45_RS12975	COG1846	Transcriptional regulator
C5I45_RS12980	COG1764	response to oxidative stress
C5I45_RS12990	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C5I45_RS12995	COG0788	formyltetrahydrofolate deformylase activity
C5I45_RS13000	COG2076	Multidrug Resistance protein
C5I45_RS13005	COG2076	Multidrug Resistance protein
C5I45_RS13010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C5I45_RS13015	COG1607	acyl-coa hydrolase
C5I45_RS13020	COG1834	amidinotransferase
C5I45_RS13025	COG2706	6-phosphogluconolactonase activity
C5I45_RS13030	COG4608	Belongs to the ABC transporter superfamily
C5I45_RS13035	COG0791	NLP P60 protein
C5I45_RS13040	COG4948	Mandelate Racemase Muconate Lactonizing
C5I45_RS13045	COG1619	proteins homologs of microcin C7 resistance protein MccF
C5I45_RS13050	COG4166	transmembrane transport
C5I45_RS13055	COG0444	Belongs to the ABC transporter superfamily
C5I45_RS13060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C5I45_RS13065	COG0601	transmembrane transport
C5I45_RS13070	COG2362	D-Aminopeptidase
C5I45_RS13075	COG0477	Major facilitator Superfamily
C5I45_RS13080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C5I45_RS13085	COG0463	Glycosyl transferase, family 2
C5I45_RS13090	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C5I45_RS13095	COG0346	lactoylglutathione lyase activity
C5I45_RS13100	COG0531	amino acid
C5I45_RS13105	COG1392	Phosphate transport regulator
C5I45_RS13110	COG0306	phosphate transporter
C5I45_RS13125	COG5632	N-Acetylmuramoyl-L-alanine amidase
C5I45_RS13125	COG3409	Peptidoglycan-binding domain 1 protein
C5I45_RS13165	COG3778	Protein conserved in bacteria
C5I45_RS13170	COG3299	homolog of phage Mu protein gp47
C5I45_RS13175	COG3628	GPW Gp25 family protein
C5I45_RS13185	COG4193	domain, Protein
C5I45_RS13190	COG1652	LysM domain
C5I45_RS13195	COG3953	SLT domain
C5I45_RS13195	COG5412	phage tail tape measure protein
C5I45_RS13195	COG5412	phage tail tape measure protein
C5I45_RS13195	COG5412	phage tail tape measure protein
C5I45_RS13195	COG3953	SLT domain
C5I45_RS13195	COG3953	SLT domain
C5I45_RS13245	COG4653	Phage capsid family
C5I45_RS13250	COG0338	D12 class N6 adenine-specific DNA methyltransferase
C5I45_RS13255	COG5518	Phage portal protein
C5I45_RS13260	COG1783	phage Terminase large subunit
C5I45_RS13265	COG3728	DNA packaging
C5I45_RS13265	COG5484	DNA packaging
C5I45_RS13270	COG1595	DNA-templated transcription, initiation
C5I45_RS13285	COG1484	DNA-dependent DNA replication
C5I45_RS13290	COG1522	sequence-specific DNA binding
C5I45_RS13300	COG1396	sequence-specific DNA binding
C5I45_RS13305	COG2856	Zn peptidase
C5I45_RS13310	COG4195	phage-related replication protein
C5I45_RS13320	COG5632	N-Acetylmuramoyl-L-alanine amidase
C5I45_RS13320	COG3409	Peptidoglycan-binding domain 1 protein
C5I45_RS13320	COG1388	LysM domain
C5I45_RS13325	COG0457	Tetratricopeptide repeat
C5I45_RS13330	COG2318	DinB family
C5I45_RS13335	COG0730	response to heat
C5I45_RS13350	COG2770	Histidine kinase
C5I45_RS13350	COG2205	protein histidine kinase activity
C5I45_RS13355	COG0745	RESPONSE REGULATOR receiver
C5I45_RS13360	COG2721	sulfolactate sulfo-lyase activity
C5I45_RS13365	COG0246	Mannitol dehydrogenase
C5I45_RS13370	COG1609	Transcriptional regulator
C5I45_RS13375	COG2211	Major facilitator Superfamily
C5I45_RS13385	COG1252	NADH dehydrogenase
C5I45_RS13395	COG4297	protein containing double-stranded beta helix domain
C5I45_RS13400	COG0697	spore germination
C5I45_RS13405	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C5I45_RS13410	COG0390	transport system, permease component
C5I45_RS13415	COG1587	Uroporphyrinogen-III synthase
C5I45_RS13425	COG1819	glycosyl
C5I45_RS13430	COG2124	cytochrome p450
C5I45_RS13435	COG2427	Protein of unknown function (DUF1641)
C5I45_RS13440	COG3383	formate dehydrogenase (NAD+) activity
C5I45_RS13450	COG2205	protein histidine kinase activity
C5I45_RS13465	COG1285	pathogenesis
C5I45_RS13485	COG1349	DNA-binding transcription factor activity
C5I45_RS13495	COG1447	Phosphotransferase system cellobiose-specific component IIA
C5I45_RS13500	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C5I45_RS13500	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C5I45_RS13505	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C5I45_RS13510	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C5I45_RS13515	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
C5I45_RS13525	COG1846	Transcriptional regulator
C5I45_RS13535	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C5I45_RS13540	COG2367	Beta-lactamase
C5I45_RS13545	COG0346	lactoylglutathione lyase activity
C5I45_RS13600	COG0626	cystathionine gamma-synthase activity
C5I45_RS13605	COG0626	cystathionine gamma-synthase activity
C5I45_RS13610	COG2382	esterase
C5I45_RS13620	COG2153	protein acetylation
C5I45_RS13630	COG1131	(ABC) transporter
C5I45_RS13650	COG0210	DNA helicase
C5I45_RS13705	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C5I45_RS13710	COG0351	phosphomethylpyrimidine kinase
C5I45_RS13715	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C5I45_RS13725	COG2104	thiamine diphosphate biosynthetic process
C5I45_RS13730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C5I45_RS13735	COG0352	thiamine-phosphate diphosphorylase activity
C5I45_RS13740	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C5I45_RS13745	COG0475	glutathione-regulated potassium exporter activity
C5I45_RS13745	COG0569	domain protein
C5I45_RS13760	COG0564	pseudouridine synthase activity
C5I45_RS13765	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C5I45_RS13770	COG2357	RelA SpoT domain protein
C5I45_RS13780	COG4116	CYTH
C5I45_RS13785	COG0741	lytic transglycosylase activity
C5I45_RS13790	COG2346	COG2346, Truncated hemoglobins
C5I45_RS13795	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C5I45_RS13800	COG1164	Oligoendopeptidase f
C5I45_RS13805	COG4469	Competence protein
C5I45_RS13810	COG4862	establishment of competence for transformation
C5I45_RS13815	COG0861	Integral membrane protein TerC family
C5I45_RS13820	COG1393	Belongs to the ArsC family
C5I45_RS13825	COG0456	acetyltransferase
C5I45_RS13835	COG4608	Belongs to the ABC transporter superfamily
C5I45_RS13840	COG0444	Belongs to the ABC transporter superfamily
C5I45_RS13845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C5I45_RS13850	COG0601	transmembrane transport
C5I45_RS13855	COG4166	transmembrane transport
C5I45_RS13860	COG0180	Tryptophanyl-tRNA synthetase
C5I45_RS13870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C5I45_RS13875	COG0601	transmembrane transport
C5I45_RS13885	COG4608	Belongs to the ABC transporter superfamily
C5I45_RS13890	COG0444	Belongs to the ABC transporter superfamily
C5I45_RS13895	COG5504	Zn-dependent protease
C5I45_RS13900	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C5I45_RS13905	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C5I45_RS13920	COG1744	ABC transporter substrate-binding protein PnrA-like
C5I45_RS13930	COG2267	carboxylic ester hydrolase activity
C5I45_RS13950	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C5I45_RS13955	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C5I45_RS13960	COG0505	Belongs to the CarA family
C5I45_RS13965	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C5I45_RS13975	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
C5I45_RS13985	COG2271	Major facilitator Superfamily
C5I45_RS13990	COG0277	FAD linked oxidase domain protein
C5I45_RS14000	COG2151	metal-sulfur cluster biosynthetic enzyme
C5I45_RS14005	COG1073	alpha beta
C5I45_RS14010	COG0561	phosphatase activity
C5I45_RS14025	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C5I45_RS14030	COG1307	EDD domain protein, DegV family
C5I45_RS14040	COG0840	transmembrane signaling receptor activity
C5I45_RS14045	COG1744	ABC transporter substrate-binding protein PnrA-like
C5I45_RS14050	COG2996	Protein conserved in bacteria
C5I45_RS14060	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C5I45_RS14060	COG0646	methionine synthase
C5I45_RS14065	COG2153	protein acetylation
C5I45_RS14070	COG1357	PFAM Pentapeptide repeats (8 copies)
C5I45_RS14080	COG2318	DinB family
C5I45_RS14085	COG0673	inositol 2-dehydrogenase activity
C5I45_RS14090	COG1609	Transcriptional regulator
C5I45_RS14095	COG2207	Transcriptional regulator
C5I45_RS14095	COG1917	Cupin 2, conserved barrel domain protein
C5I45_RS14100	COG0534	Mate efflux family protein
C5I45_RS14105	COG1562	ergosterol biosynthetic process
C5I45_RS14110	COG0367	asparagine synthase
C5I45_RS14130	COG0179	Fumarylacetoacetate (FAA) hydrolase
C5I45_RS14170	COG1403	HNH endonuclease
C5I45_RS14175	COG0419	ATPase involved in DNA repair
C5I45_RS14180	COG0420	3'-5' exonuclease activity
C5I45_RS14195	COG2323	membrane
C5I45_RS14200	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
C5I45_RS14210	COG2814	Major facilitator Superfamily
C5I45_RS14215	COG3180	Ammonia monooxygenase
C5I45_RS14220	COG1846	Transcriptional regulator
C5I45_RS14225	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C5I45_RS14230	COG0681	Belongs to the peptidase S26 family
C5I45_RS14235	COG0398	Pfam SNARE associated Golgi protein
C5I45_RS14250	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C5I45_RS14270	COG5646	InterPro IPR014922
C5I45_RS14290	COG4903	ComK protein
C5I45_RS14300	COG1028	Short-chain dehydrogenase reductase Sdr
C5I45_RS14305	COG0723	plastoquinol--plastocyanin reductase activity
C5I45_RS14305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C5I45_RS14310	COG0840	transmembrane signaling receptor activity
C5I45_RS14315	COG1268	BioY protein
C5I45_RS14320	COG0318	PFAM AMP-dependent synthetase and ligase
C5I45_RS14325	COG0183	Belongs to the thiolase family
C5I45_RS14330	COG0406	alpha-ribazole phosphatase activity
C5I45_RS14335	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
C5I45_RS14345	COG1404	Belongs to the peptidase S8 family
C5I45_RS14350	COG0501	Belongs to the peptidase M48B family
C5I45_RS14360	COG0318	PFAM AMP-dependent synthetase and ligase
C5I45_RS14365	COG0702	epimerase
C5I45_RS14370	COG0095	Lipoate-protein ligase
C5I45_RS14375	COG1234	tRNA 3'-trailer cleavage
C5I45_RS14385	COG1301	dicarboxylic acid transport
C5I45_RS14390	COG1363	Peptidase, m42
C5I45_RS14400	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C5I45_RS14405	COG1511	domain protein
C5I45_RS14410	COG1309	transcriptional regulator
C5I45_RS14415	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
C5I45_RS14420	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
C5I45_RS14430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C5I45_RS14435	COG2329	Antibiotic biosynthesis monooxygenase
C5I45_RS14440	COG3069	C4-dicarboxylate transmembrane transporter activity
C5I45_RS14445	COG1473	amidohydrolase
C5I45_RS14455	COG4473	ABC transporter
C5I45_RS14460	COG1131	(ABC) transporter
C5I45_RS14465	COG0537	adenosine 5'-monophosphoramidase activity
C5I45_RS14470	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C5I45_RS14485	COG4980	gas vesicle protein
C5I45_RS14525	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C5I45_RS14540	COG4717	serine-type aminopeptidase activity
C5I45_RS14545	COG0420	3'-5' exonuclease activity
C5I45_RS14550	COG1668	transmembrane transport
C5I45_RS14555	COG4152	abc transporter atp-binding protein
C5I45_RS14565	COG1024	Enoyl-CoA hydratase
C5I45_RS14575	COG0490	domain, Protein
C5I45_RS14580	COG0475	glutathione-regulated potassium exporter activity
C5I45_RS14590	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C5I45_RS14595	COG0561	phosphatase activity
C5I45_RS14600	COG4335	DNA alkylation repair
C5I45_RS14615	COG0189	ligase activity
C5I45_RS14620	COG0189	ligase activity
C5I45_RS14640	COG0702	epimerase
C5I45_RS14645	COG1132	(ABC) transporter
C5I45_RS14650	COG1132	(ABC) transporter
C5I45_RS14655	COG0589	response to stress
C5I45_RS14665	COG3226	Transcriptional regulator
C5I45_RS14670	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C5I45_RS14675	COG0726	polysaccharide deacetylase
C5I45_RS14680	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C5I45_RS14685	COG0668	transmembrane transport
C5I45_RS14695	COG0584	glycerophosphoryl diester phosphodiesterase
C5I45_RS14700	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C5I45_RS14705	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C5I45_RS14710	COG1253	flavin adenine dinucleotide binding
C5I45_RS14715	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C5I45_RS14720	COG0436	Aminotransferase
C5I45_RS14725	COG0789	Transcriptional regulator
C5I45_RS14730	COG1253	flavin adenine dinucleotide binding
C5I45_RS14735	COG0204	Acyl-transferase
C5I45_RS14740	COG1595	DNA-templated transcription, initiation
C5I45_RS14755	COG0733	neurotransmitter:sodium symporter activity
C5I45_RS14760	COG0531	amino acid
C5I45_RS14765	COG1028	Short-chain dehydrogenase reductase Sdr
C5I45_RS14770	COG0372	Belongs to the citrate synthase family
C5I45_RS14775	COG0583	DNA-binding transcription factor activity
C5I45_RS14780	COG1388	LysM domain
C5I45_RS14780	COG0791	NLP P60 protein
C5I45_RS14785	COG1785	Belongs to the alkaline phosphatase family
C5I45_RS14790	COG2719	SpoVR family
C5I45_RS14795	COG0668	transmembrane transport
C5I45_RS14800	COG1959	2 iron, 2 sulfur cluster binding
C5I45_RS14805	COG1388	LysM domain
C5I45_RS14805	COG0791	NLP P60 protein
C5I45_RS14820	COG0431	NADPH-dependent FMN reductase
C5I45_RS14825	COG2197	response regulator
C5I45_RS14830	COG4585	Histidine kinase
C5I45_RS14830	COG2203	Gaf domain
C5I45_RS14835	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C5I45_RS14840	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C5I45_RS14850	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C5I45_RS14855	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
C5I45_RS14860	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C5I45_RS14865	COG3153	acetyltransferase
C5I45_RS14865	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C5I45_RS14870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C5I45_RS14875	COG0517	IMP dehydrogenase activity
C5I45_RS14885	COG0564	pseudouridine synthase activity
C5I45_RS14890	COG3764	Sortase (surface protein transpeptidase)
C5I45_RS14895	COG1525	nuclease
C5I45_RS14895	COG0737	Belongs to the 5'-nucleotidase family
C5I45_RS14895	COG4085	toxin activity
C5I45_RS14900	COG5577	PFAM Coat F domain
C5I45_RS14920	COG1823	symporter activity
C5I45_RS14925	COG3706	GGDEF domain
C5I45_RS14930	COG1464	Belongs to the NlpA lipoprotein family
C5I45_RS14940	COG1278	Cold shock
C5I45_RS14945	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C5I45_RS14950	COG1131	(ABC) transporter
C5I45_RS14955	COG1131	(ABC) transporter
C5I45_RS14960	COG1725	Transcriptional regulator
C5I45_RS14975	COG0655	NAD(P)H dehydrogenase (quinone) activity
C5I45_RS14980	COG2814	Major facilitator Superfamily
C5I45_RS14985	COG1566	PFAM secretion protein HlyD family protein
C5I45_RS14990	COG1846	Transcriptional regulator
C5I45_RS15005	COG2766	serine protein kinase
C5I45_RS15010	COG1664	Polymer-forming cytoskeletal
C5I45_RS15015	COG1664	Polymer-forming cytoskeletal
C5I45_RS15020	COG0789	Transcriptional regulator
C5I45_RS15025	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C5I45_RS15035	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C5I45_RS15040	COG3382	B3 4 domain protein
C5I45_RS15050	COG1476	TRANSCRIPTIONal
C5I45_RS15070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C5I45_RS15075	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C5I45_RS15080	COG1116	anion transmembrane transporter activity
C5I45_RS15095	COG0753	catalase activity
C5I45_RS15100	COG4608	Belongs to the ABC transporter superfamily
C5I45_RS15105	COG0444	Belongs to the ABC transporter superfamily
C5I45_RS15110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C5I45_RS15115	COG0601	transmembrane transport
C5I45_RS15120	COG0747	negative chemotaxis
C5I45_RS15130	COG0277	FAD linked oxidase domain protein
C5I45_RS15140	COG3340	Belongs to the peptidase S51 family
C5I45_RS15255	COG0735	belongs to the Fur family
C5I45_RS15260	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C5I45_RS15270	COG4129	membrane
C5I45_RS15275	COG1132	(ABC) transporter
C5I45_RS15295	COG1028	Short-chain dehydrogenase reductase Sdr
C5I45_RS15305	COG1194	a g-specific adenine glycosylase
C5I45_RS15310	COG1988	membrane-bound metal-dependent
C5I45_RS15315	COG4485	Bacterial membrane protein, YfhO
C5I45_RS15320	COG0463	Glycosyl transferase, family 2
C5I45_RS15325	COG0596	Alpha beta hydrolase
C5I45_RS15330	COG5658	integral membrane protein
C5I45_RS15335	COG3103	Sh3 type 3 domain protein
C5I45_RS15350	COG3591	Belongs to the peptidase S1B family
C5I45_RS15360	COG2814	Major facilitator Superfamily
C5I45_RS15375	COG1090	epimerase
C5I45_RS15390	COG0778	Nitroreductase
C5I45_RS15395	COG0384	phenazine biosynthesis protein PhzF
C5I45_RS15400	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
C5I45_RS15400	COG0392	lysyltransferase activity
C5I45_RS15405	COG1846	Transcriptional regulator
C5I45_RS15410	COG2814	Major facilitator Superfamily
C5I45_RS15415	COG2318	DinB family
C5I45_RS15420	COG2732	(Barnase) inhibitor
C5I45_RS15425	COG0574	Belongs to the PEP-utilizing enzyme family
C5I45_RS15425	COG3848	Pyruvate phosphate dikinase
C5I45_RS15430	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
C5I45_RS15435	COG2249	NAD(P)H dehydrogenase (quinone) activity
C5I45_RS15440	COG1695	Transcriptional regulator
C5I45_RS15455	COG2514	catechol 2,3-dioxygenase activity
C5I45_RS15460	COG2259	Doxx family
C5I45_RS15465	COG1132	(ABC) transporter
C5I45_RS15470	COG1132	(ABC) transporter
C5I45_RS15475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C5I45_RS15475	COG1263	PTS System
C5I45_RS15480	COG1737	Transcriptional regulator
C5I45_RS15485	COG1486	melibiose metabolic process
C5I45_RS15495	COG3284	Transcriptional regulator
C5I45_RS15500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C5I45_RS15505	COG0508	dehydrogenase complex catalyzes the overall conversion of
C5I45_RS15510	COG0022	dehydrogenase e1 component
C5I45_RS15515	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C5I45_RS15520	COG4637	Psort location Cytoplasmic, score
C5I45_RS15525	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C5I45_RS15535	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C5I45_RS15540	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C5I45_RS15545	COG0598	Magnesium transport protein CorA
C5I45_RS15555	COG2084	Dehydrogenase
C5I45_RS15560	COG0726	polysaccharide deacetylase
C5I45_RS15570	COG0535	radical SAM domain protein
C5I45_RS15575	COG0668	transmembrane transport
C5I45_RS15585	COG0387	Pfam Sodium calcium exchanger
C5I45_RS15590	COG0477	Major facilitator Superfamily
C5I45_RS15595	COG1295	ribonuclease BN
C5I45_RS15600	COG4980	gas vesicle protein
C5I45_RS15605	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C5I45_RS15615	COG2814	Major facilitator Superfamily
C5I45_RS15630	COG1609	Transcriptional regulator
C5I45_RS15635	COG0693	protein deglycase activity
C5I45_RS15640	COG0737	Belongs to the 5'-nucleotidase family
C5I45_RS15655	COG0778	Nitroreductase
C5I45_RS15660	COG2188	Transcriptional regulator
C5I45_RS15665	COG0366	Alpha amylase catalytic
C5I45_RS15670	COG1263	PTS System
C5I45_RS15670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C5I45_RS15685	COG0071	Belongs to the small heat shock protein (HSP20) family
C5I45_RS15695	COG1368	sulfuric ester hydrolase activity
C5I45_RS15705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C5I45_RS15705	COG1263	PTS System
C5I45_RS15710	COG0024	Methionine aminopeptidase
C5I45_RS15730	COG2258	MOSC domain
C5I45_RS15740	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
C5I45_RS15745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C5I45_RS15750	COG2851	Citrate transporter
C5I45_RS15755	COG3181	Tripartite tricarboxylate transporter family receptor
C5I45_RS15760	COG4565	transcriptional regulatory protein
C5I45_RS15765	COG3290	protein histidine kinase activity
C5I45_RS15780	COG0471	metal ion transport
C5I45_RS15785	COG3866	Pectate lyase
C5I45_RS15800	COG2130	NADP-dependent
C5I45_RS15810	COG0513	Belongs to the DEAD box helicase family
C5I45_RS15815	COG0488	(ABC) transporter
C5I45_RS15820	COG2814	Major facilitator Superfamily
C5I45_RS15825	COG0789	Transcriptional regulator
C5I45_RS15830	COG0488	(ABC) transporter
C5I45_RS15835	COG0457	Tetratricopeptide repeat
C5I45_RS15835	COG0463	Glycosyl transferase, family 2
C5I45_RS15840	COG1028	Short-chain dehydrogenase reductase Sdr
C5I45_RS15845	COG0840	transmembrane signaling receptor activity
C5I45_RS15850	COG1012	belongs to the aldehyde dehydrogenase family
C5I45_RS15855	COG0531	amino acid
C5I45_RS15860	COG2223	nitrite transmembrane transporter activity
C5I45_RS15865	COG1442	glycosyl transferase family 8
C5I45_RS15870	COG1216	Glycosyl transferase, family 2
C5I45_RS15875	COG1442	glycosyl transferase family 8
C5I45_RS15880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C5I45_RS15885	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C5I45_RS15890	COG1368	sulfuric ester hydrolase activity
C5I45_RS15900	COG1131	(ABC) transporter
C5I45_RS15915	COG2124	cytochrome p450
C5I45_RS15915	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C5I45_RS15925	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C5I45_RS15930	COG1846	Transcriptional regulator
C5I45_RS15935	COG0670	Belongs to the BI1 family
C5I45_RS15940	COG0196	riboflavin kinase activity
C5I45_RS15945	COG5583	Uncharacterized small protein (DUF2292)
C5I45_RS15950	COG1366	Belongs to the anti-sigma-factor antagonist family
C5I45_RS15955	COG0346	lactoylglutathione lyase activity
C5I45_RS15960	COG2329	Antibiotic biosynthesis monooxygenase
C5I45_RS15965	COG2323	membrane
C5I45_RS15975	COG0454	-acetyltransferase
C5I45_RS15980	COG3546	catalase activity
C5I45_RS16035	COG1131	(ABC) transporter
C5I45_RS16040	COG1028	Short-chain dehydrogenase reductase Sdr
C5I45_RS16050	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C5I45_RS16060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C5I45_RS16070	COG2197	response regulator
C5I45_RS16075	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C5I45_RS16080	COG1597	lipid kinase activity
C5I45_RS16085	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C5I45_RS16090	COG1309	transcriptional regulator
C5I45_RS16110	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C5I45_RS16115	COG1285	pathogenesis
C5I45_RS16120	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C5I45_RS16125	COG4851	CamS sex pheromone cAM373 precursor
C5I45_RS16135	COG0210	DNA helicase
C5I45_RS16150	COG0069	glutamate synthase activity
C5I45_RS16155	COG4496	protein, YerC YecD
C5I45_RS16160	COG1470	cell adhesion involved in biofilm formation
C5I45_RS16165	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C5I45_RS16175	COG0151	Belongs to the GarS family
C5I45_RS16180	COG0138	bifunctional purine biosynthesis protein purh
C5I45_RS16185	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C5I45_RS16195	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C5I45_RS16210	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C5I45_RS16215	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C5I45_RS16220	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C5I45_RS16225	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C5I45_RS16230	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C5I45_RS16250	COG3064	Membrane
C5I45_RS16255	COG2252	PERMEase
C5I45_RS16275	COG1305	Transglutaminase-like
C5I45_RS16280	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
C5I45_RS16285	COG0714	Associated with various cellular activities
C5I45_RS16290	COG1113	amino acid transport
C5I45_RS16295	COG2132	Multicopper oxidase
C5I45_RS16305	COG0823	Involved in the tonB-independent uptake of proteins
C5I45_RS16310	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C5I45_RS16315	COG1063	alcohol dehydrogenase
C5I45_RS16320	COG1595	DNA-templated transcription, initiation
C5I45_RS16330	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C5I45_RS16330	COG2755	lipolytic protein G-D-S-L family
C5I45_RS16335	COG4260	virion core protein, lumpy skin disease virus
C5I45_RS16340	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
C5I45_RS16345	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C5I45_RS16350	COG1842	Phage shock protein A
C5I45_RS16360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C5I45_RS16365	COG2211	Major facilitator Superfamily
C5I45_RS16370	COG1063	alcohol dehydrogenase
C5I45_RS16375	COG0457	Tetratricopeptide repeat
C5I45_RS16405	COG1266	CAAX protease self-immunity
C5I45_RS16415	COG0805	protein transport
C5I45_RS16420	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C5I45_RS16435	COG0488	(ABC) transporter
C5I45_RS16440	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C5I45_RS16445	COG0456	acetyltransferase
C5I45_RS16450	COG1214	PFAM Peptidase M22, glycoprotease
C5I45_RS16455	COG0802	atpase or kinase
C5I45_RS16460	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C5I45_RS16500	COG2814	Major facilitator Superfamily
C5I45_RS16505	COG0604	alcohol dehydrogenase
C5I45_RS16510	COG3832	glyoxalase III activity
C5I45_RS16520	COG0531	amino acid
C5I45_RS16525	COG1309	transcriptional regulator
C5I45_RS16530	COG2076	Multidrug Resistance protein
C5I45_RS16535	COG2076	Multidrug Resistance protein
C5I45_RS16540	COG2807	transmembrane transport
C5I45_RS16545	COG2186	Transcriptional regulator
C5I45_RS16550	COG2188	Transcriptional regulator
C5I45_RS16555	COG2814	Major facilitator Superfamily
C5I45_RS16560	COG1388	LysM domain
C5I45_RS16565	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C5I45_RS16580	COG1819	glycosyl
C5I45_RS16585	COG1802	Transcriptional regulator
C5I45_RS16590	COG0473	3-isopropylmalate dehydrogenase activity
C5I45_RS16595	COG2226	methyltransferase
C5I45_RS16600	COG1051	belongs to the nudix hydrolase family
C5I45_RS16605	COG0697	spore germination
C5I45_RS16610	COG4978	Transcriptional regulator
C5I45_RS16610	COG0789	Transcriptional regulator
C5I45_RS16615	COG0456	acetyltransferase
C5I45_RS16620	COG0730	response to heat
C5I45_RS16630	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C5I45_RS16635	COG2814	Major facilitator Superfamily
C5I45_RS16645	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C5I45_RS16650	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C5I45_RS16655	COG0488	(ABC) transporter
C5I45_RS16660	COG1959	2 iron, 2 sulfur cluster binding
C5I45_RS16665	COG0477	Major facilitator Superfamily
C5I45_RS16670	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C5I45_RS16675	COG2409	Drug exporters of the RND superfamily
C5I45_RS16680	COG2197	response regulator
C5I45_RS16685	COG4585	Histidine kinase
C5I45_RS16695	COG5577	PFAM Coat F domain
C5I45_RS16700	COG1063	alcohol dehydrogenase
C5I45_RS16710	COG5577	PFAM Coat F domain
C5I45_RS16720	COG1309	transcriptional regulator
C5I45_RS16725	COG2814	Major facilitator Superfamily
C5I45_RS16740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C5I45_RS16750	COG0789	Transcriptional regulator
C5I45_RS16755	COG1064	alcohol dehydrogenase
C5I45_RS16780	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C5I45_RS16815	COG0277	FAD linked oxidase domain protein
C5I45_RS16835	COG0477	Major facilitator Superfamily
C5I45_RS16840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C5I45_RS16850	COG1917	Cupin 2, conserved barrel domain protein
C5I45_RS16850	COG2207	Transcriptional regulator
C5I45_RS16855	COG1473	amidohydrolase
C5I45_RS16860	COG0814	amino acid
C5I45_RS16865	COG0251	oxidation-reduction process
C5I45_RS16870	COG1802	Transcriptional regulator
C5I45_RS16875	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C5I45_RS16885	COG3621	Patatin-like phospholipase
C5I45_RS16900	COG1794	racemase activity, acting on amino acids and derivatives
C5I45_RS16905	COG0730	response to heat
C5I45_RS16910	COG0425	Belongs to the sulfur carrier protein TusA family
C5I45_RS16915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C5I45_RS16915	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C5I45_RS16920	COG0425	Belongs to the sulfur carrier protein TusA family
C5I45_RS16920	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C5I45_RS16930	COG2210	Belongs to the sulfur carrier protein TusA family
C5I45_RS16935	COG1937	Protein conserved in bacteria
C5I45_RS16945	COG1278	Cold shock
C5I45_RS16950	COG2910	NAD(P)H-binding
C5I45_RS16955	COG1959	2 iron, 2 sulfur cluster binding
C5I45_RS16960	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C5I45_RS16970	COG2030	dehydratase
C5I45_RS16980	COG1846	Transcriptional regulator
C5I45_RS16985	COG1764	response to oxidative stress
C5I45_RS16995	COG0477	Major facilitator Superfamily
C5I45_RS17000	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C5I45_RS17020	COG2249	NAD(P)H dehydrogenase (quinone) activity
C5I45_RS17070	COG2183	response to ionizing radiation
C5I45_RS17075	COG2208	phosphoserine phosphatase activity
C5I45_RS17080	COG1191	sigma factor activity
C5I45_RS17090	COG1366	Belongs to the anti-sigma-factor antagonist family
C5I45_RS17095	COG2208	phosphoserine phosphatase activity
C5I45_RS17100	COG2172	sigma factor antagonist activity
C5I45_RS17105	COG1366	Belongs to the anti-sigma-factor antagonist family
C5I45_RS17110	COG1366	Belongs to the anti-sigma-factor antagonist family
C5I45_RS17115	COG2337	Toxic component of a toxin-antitoxin (TA) module
C5I45_RS17120	COG0864	Transcriptional regulator
C5I45_RS17125	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C5I45_RS17130	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C5I45_RS17140	COG0705	Rhomboid family
C5I45_RS17145	COG3428	Bacterial PH domain
C5I45_RS17150	COG3402	PFAM membrane-flanked domain
C5I45_RS17155	COG0513	Belongs to the DEAD box helicase family
C5I45_RS17160	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C5I45_RS17170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C5I45_RS17175	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C5I45_RS17190	COG1960	acyl-CoA dehydrogenase activity
C5I45_RS17200	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C5I45_RS17205	COG1131	(ABC) transporter
C5I45_RS17210	COG0628	permease
C5I45_RS17215	COG1301	dicarboxylic acid transport
C5I45_RS17220	COG4565	transcriptional regulatory protein
C5I45_RS17225	COG3290	protein histidine kinase activity
C5I45_RS17230	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C5I45_RS17235	COG3546	catalase activity
C5I45_RS17240	COG2329	Antibiotic biosynthesis monooxygenase
C5I45_RS17245	COG0662	Cupin 2, conserved barrel domain protein
C5I45_RS17250	COG3729	General stress protein
C5I45_RS17255	COG2217	Heavy metal translocating P-type atpase
C5I45_RS17260	COG2076	Multidrug Resistance protein
C5I45_RS17270	COG4876	unkown
C5I45_RS17285	COG1914	H( )-stimulated, divalent metal cation uptake system
C5I45_RS17360	COG0028	Belongs to the TPP enzyme family
C5I45_RS17365	COG0494	nUDIX hydrolase
C5I45_RS17370	COG0531	amino acid
C5I45_RS17380	COG1215	transferase activity, transferring glycosyl groups
C5I45_RS17385	COG5298	Protein conserved in bacteria
C5I45_RS17390	COG3706	GGDEF domain
C5I45_RS17395	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
C5I45_RS17400	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C5I45_RS17400	COG0551	DNA topoisomerase type I activity
C5I45_RS17405	COG1522	sequence-specific DNA binding
C5I45_RS17410	COG2814	Major facilitator Superfamily
C5I45_RS17420	COG3871	stress protein (general stress protein 26)
C5I45_RS17425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C5I45_RS17430	COG1917	Cupin 2, conserved barrel domain protein
C5I45_RS17435	COG1028	Short-chain dehydrogenase reductase Sdr
C5I45_RS17440	COG0318	PFAM AMP-dependent synthetase and ligase
C5I45_RS17445	COG3711	transcriptional antiterminator
C5I45_RS17450	COG4989	oxidoreductase activity
C5I45_RS17455	COG0768	penicillin binding
C5I45_RS17460	COG2329	Antibiotic biosynthesis monooxygenase
C5I45_RS17470	COG2755	lipolytic protein G-D-S-L family
C5I45_RS17475	COG1414	Transcriptional regulator
C5I45_RS17480	COG1984	allophanate hydrolase subunit 2
C5I45_RS17485	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C5I45_RS17495	COG1914	H( )-stimulated, divalent metal cation uptake system
C5I45_RS17505	COG0561	phosphatase activity
C5I45_RS17515	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C5I45_RS17525	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5I45_RS17530	COG2213	PTS system mannitol-specific
C5I45_RS17540	COG1349	DNA-binding transcription factor activity
C5I45_RS17545	COG2372	response to copper ion
C5I45_RS17545	COG1276	copper resistance
C5I45_RS17550	COG4549	nuclear export factor GLE1
C5I45_RS17555	COG1028	Short-chain dehydrogenase reductase Sdr
C5I45_RS17560	COG4975	Glucose uptake
C5I45_RS17565	COG1012	belongs to the aldehyde dehydrogenase family
C5I45_RS17570	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C5I45_RS17575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C5I45_RS17580	COG0640	Transcriptional regulator
C5I45_RS17585	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C5I45_RS17590	COG0778	Nitroreductase
C5I45_RS17595	COG1309	transcriptional regulator
C5I45_RS17600	COG2814	Major facilitator Superfamily
C5I45_RS17605	COG4607	ABC-type enterochelin transport system periplasmic component
C5I45_RS17610	COG4604	ABC transporter, ATP-binding protein
C5I45_RS17615	COG4605	iron ion homeostasis
C5I45_RS17620	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C5I45_RS17630	COG0527	aspartate kinase activity
C5I45_RS17645	COG0457	Tetratricopeptide repeat
C5I45_RS17650	COG3850	Histidine kinase
C5I45_RS17650	COG5002	protein histidine kinase activity
C5I45_RS17655	COG0745	RESPONSE REGULATOR receiver
C5I45_RS17660	COG0577	efflux transmembrane transporter activity
C5I45_RS17665	COG1136	(ABC) transporter
C5I45_RS17670	COG2079	MmgE PrpD family protein
C5I45_RS17675	COG1473	amidohydrolase
C5I45_RS17680	COG1126	abc transporter atp-binding protein
C5I45_RS17685	COG0765	amino acid transport
C5I45_RS17690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5I45_RS17695	COG0456	acetyltransferase
C5I45_RS17700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C5I45_RS17705	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C5I45_RS17715	COG0697	spore germination
C5I45_RS17725	COG5434	Belongs to the glycosyl hydrolase 28 family
C5I45_RS17730	COG3104	oligopeptide transport
C5I45_RS17745	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C5I45_RS17750	COG0163	prenyltransferase activity
C5I45_RS17755	COG0583	DNA-binding transcription factor activity
C5I45_RS17760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5I45_RS17765	COG0765	amino acid transport
C5I45_RS17770	COG1126	abc transporter atp-binding protein
C5I45_RS17775	COG2364	Membrane
C5I45_RS17790	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
C5I45_RS17795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C5I45_RS17800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C5I45_RS17805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C5I45_RS17810	COG1733	regulation of RNA biosynthetic process
C5I45_RS17815	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
C5I45_RS17820	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C5I45_RS17825	COG3209	COG3209 Rhs family protein
C5I45_RS17840	COG2723	6-phospho-beta-galactosidase activity
C5I45_RS17850	COG1714	RDD family
C5I45_RS17855	COG1063	alcohol dehydrogenase
C5I45_RS17860	COG0523	cobalamin synthesis protein
C5I45_RS17870	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C5I45_RS17875	COG2146	nitrite reductase [NAD(P)H] activity
C5I45_RS17880	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C5I45_RS17880	COG1587	Uroporphyrinogen-III synthase
C5I45_RS17890	COG2508	Transcriptional regulator
C5I45_RS17895	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C5I45_RS17900	COG1012	belongs to the aldehyde dehydrogenase family
C5I45_RS17905	COG0506	proline dehydrogenase activity
C5I45_RS17910	COG3541	Predicted nucleotidyltransferase
C5I45_RS17915	COG3458	cephalosporin-C deacetylase activity
C5I45_RS17920	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C5I45_RS17925	COG2271	Major facilitator Superfamily
C5I45_RS17930	COG1082	Xylose isomerase domain protein TIM barrel
C5I45_RS17935	COG1660	Displays ATPase and GTPase activities
C5I45_RS17950	COG3665	Urea carboxylase-associated protein
C5I45_RS17955	COG1113	amino acid transport
C5I45_RS17960	COG3403	YqcI/YcgG family
C5I45_RS17965	COG1280	lysine exporter protein (LysE YggA)
C5I45_RS17970	COG1846	Transcriptional regulator
C5I45_RS17975	COG2814	Major facilitator Superfamily
C5I45_RS18000	COG1288	antiporter activity
C5I45_RS18005	COG1473	amidohydrolase
C5I45_RS18010	COG2113	Glycine betaine
C5I45_RS18015	COG4176	ABC-type proline glycine betaine transport system permease component
C5I45_RS18020	COG4175	Glycine betaine
C5I45_RS18020	COG0517	IMP dehydrogenase activity
C5I45_RS18025	COG0477	Major facilitator Superfamily
C5I45_RS18030	COG3853	Toxic anion resistance protein (TelA)
C5I45_RS18040	COG0861	Integral membrane protein TerC family
C5I45_RS18045	COG2310	stress, protein
C5I45_RS18050	COG2310	stress, protein
C5I45_RS18055	COG2310	stress, protein
C5I45_RS18060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C5I45_RS18065	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C5I45_RS18070	COG1121	(ABC) transporter
C5I45_RS18075	COG0803	Belongs to the bacterial solute-binding protein 9 family
C5I45_RS18080	COG0366	Alpha amylase catalytic
C5I45_RS18085	COG1028	Short-chain dehydrogenase reductase Sdr
C5I45_RS18090	COG0457	Tetratricopeptide repeat
C5I45_RS18095	COG1876	peptidase activity
C5I45_RS18100	COG1595	DNA-templated transcription, initiation
C5I45_RS18105	COG1595	DNA-templated transcription, initiation
C5I45_RS18115	COG0667	Aldo Keto reductase
C5I45_RS18120	COG3012	SEC-C Motif Domain Protein
C5I45_RS18120	COG1405	negative regulation of cell septum assembly
C5I45_RS18125	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
C5I45_RS18130	COG0252	asparaginase activity
C5I45_RS18135	COG1309	transcriptional regulator
C5I45_RS18140	COG0477	Major facilitator Superfamily
C5I45_RS18145	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C5I45_RS18155	COG0805	protein transport
C5I45_RS18160	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C5I45_RS18165	COG3540	Alkaline phosphatase
C5I45_RS18175	COG3773	Cell wall hydrolase
C5I45_RS18190	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C5I45_RS18195	COG2259	Doxx family
C5I45_RS18200	COG0346	lactoylglutathione lyase activity
C5I45_RS18205	COG0778	Nitroreductase
C5I45_RS18210	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C5I45_RS18220	COG3173	Aminoglycoside phosphotransferase
C5I45_RS18225	COG0784	Response regulator, receiver
C5I45_RS18230	COG4191	Histidine kinase
C5I45_RS18235	COG2066	Belongs to the glutaminase family
C5I45_RS18240	COG1115	amino acid carrier protein
C5I45_RS18245	COG2040	homocysteine
C5I45_RS18250	COG0833	amino acid
C5I45_RS18255	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C5I45_RS18260	COG1301	dicarboxylic acid transport
C5I45_RS18275	COG0688	phosphatidylethanolamine metabolic process
C5I45_RS18280	COG0586	Pfam SNARE associated Golgi protein
C5I45_RS18285	COG1183	phosphatidylcholine synthase activity
C5I45_RS18295	COG0371	Dehydrogenase
C5I45_RS18310	COG3409	Peptidoglycan-binding domain 1 protein
C5I45_RS18320	COG2368	4-hydroxyphenylacetate
C5I45_RS18335	COG2271	Major facilitator Superfamily
C5I45_RS18340	COG0584	glycerophosphoryl diester phosphodiesterase
C5I45_RS18355	COG0531	amino acid
C5I45_RS18395	COG1131	(ABC) transporter
C5I45_RS18400	COG2197	response regulator
C5I45_RS18405	COG4585	Histidine kinase
C5I45_RS18410	COG1011	Hydrolase
C5I45_RS18415	COG1113	amino acid transport
C5I45_RS18420	COG1846	Transcriptional regulator
C5I45_RS18425	COG1380	Effector of murein hydrolase LrgA
C5I45_RS18430	COG1346	cytolysis
C5I45_RS18470	COG4856	YbbR-like protein
C5I45_RS18475	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C5I45_RS18480	COG5662	AntiSigma factor
C5I45_RS18485	COG1595	DNA-templated transcription, initiation
C5I45_RS18515	COG1683	Conserved Protein
C5I45_RS18520	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C5I45_RS18530	COG1263	PTS System
C5I45_RS18530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C5I45_RS18535	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C5I45_RS18540	COG1472	Belongs to the glycosyl hydrolase 3 family
C5I45_RS18545	COG3876	Protein conserved in bacteria
C5I45_RS18550	COG2207	Transcriptional regulator
C5I45_RS18550	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C5I45_RS18555	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C5I45_RS18560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C5I45_RS18565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C5I45_RS18570	COG2819	hydrolase of the alpha beta superfamily
C5I45_RS18575	COG0385	Bile acid
C5I45_RS18580	COG0659	secondary active sulfate transmembrane transporter activity
C5I45_RS18595	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C5I45_RS18600	COG0738	Major facilitator superfamily
C5I45_RS18660	COG0726	polysaccharide deacetylase
C5I45_RS18665	COG2194	sulfuric ester hydrolase activity
C5I45_RS18675	COG0489	protein tyrosine kinase activity
C5I45_RS18680	COG0860	N-Acetylmuramoyl-L-alanine amidase
C5I45_RS18690	COG2318	DinB family
C5I45_RS18695	COG2226	methyltransferase
C5I45_RS18715	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C5I45_RS18720	COG1122	ATPase activity
C5I45_RS18725	COG1122	ATPase activity
C5I45_RS18750	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C5I45_RS18765	COG0024	Methionine aminopeptidase
C5I45_RS18775	COG0201	protein transport
C5I45_RS18885	COG0596	Alpha beta hydrolase
C5I45_RS18910	COG1358	cellular component organization or biogenesis
C5I45_RS18925	COG2813	Specifically methylates the guanine in position
C5I45_RS18950	COG0250	Participates in transcription elongation, termination and antitermination
C5I45_RS18955	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C5I45_RS18965	COG1595	DNA-templated transcription, initiation
C5I45_RS18970	COG3688	RNA-binding protein containing a PIN domain
C5I45_RS18975	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C5I45_RS18980	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
C5I45_RS18990	COG1045	serine acetyltransferase
C5I45_RS19015	COG4956	integral membrane protein (PIN domain superfamily)
C5I45_RS19020	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
C5I45_RS19025	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C5I45_RS19035	COG1132	(ABC) transporter
C5I45_RS19050	COG0542	response to heat
C5I45_RS19060	COG3880	PFAM UvrB UvrC protein
C5I45_RS19065	COG4463	regulation of RNA biosynthetic process
C5I45_RS19145	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C5I45_RS19150	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C5I45_RS19155	COG1396	sequence-specific DNA binding
C5I45_RS19160	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C5I45_RS19165	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C5I45_RS19170	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C5I45_RS19175	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C5I45_RS19180	COG0512	Glutamine amidotransferase of anthranilate synthase
C5I45_RS19185	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C5I45_RS19190	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C5I45_RS19195	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C5I45_RS19210	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C5I45_RS19215	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
C5I45_RS19220	COG0037	tRNA processing
C5I45_RS19225	COG0515	serine threonine protein kinase
C5I45_RS19230	COG2304	oxidoreductase activity
C5I45_RS19235	COG2208	phosphoserine phosphatase activity
C5I45_RS19250	COG1098	S1 RNA binding domain
C5I45_RS19255	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
C5I45_RS19270	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C5I45_RS19275	COG3956	TIGRFAM MazG family protein
C5I45_RS19280	COG2244	polysaccharide biosynthetic process
C5I45_RS19285	COG2002	toxin-antitoxin pair type II binding
C5I45_RS19290	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C5I45_RS19310	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C5I45_RS19325	COG0251	oxidation-reduction process
C5I45_RS19330	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C5I45_RS19345	COG4466	Protein conserved in bacteria
C5I45_RS19355	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C5I45_RS19360	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C5I45_RS19365	COG3583	domain protein
C5I45_RS19365	COG3584	3D domain protein
C5I45_RS19370	COG0084	hydrolase, TatD family'
C5I45_RS19375	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C5I45_RS19375	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C5I45_RS19380	COG2002	toxin-antitoxin pair type II binding
C5I45_RS19385	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C5I45_RS19395	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C5I45_RS19405	COG1774	PSP1 C-terminal conserved region
C5I45_RS19410	COG0470	DNA polymerase III
C5I45_RS19415	COG1728	Protein conserved in bacteria
C5I45_RS19420	COG3870	Protein conserved in bacteria
C5I45_RS19430	COG1982	Orn Lys Arg decarboxylase major
C5I45_RS19435	COG3853	Toxic anion resistance protein (TelA)
C5I45_RS19440	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
C5I45_RS19490	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C5I45_RS19495	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C5I45_RS19505	COG0590	tRNA wobble adenosine to inosine editing
C5I45_RS19510	COG1335	isochorismatase
C5I45_RS19515	COG3858	chitin binding
C5I45_RS19515	COG1388	LysM domain
C5I45_RS19520	COG1428	Deoxynucleoside kinase
C5I45_RS19525	COG1428	Deoxynucleoside kinase
C5I45_RS19535	COG1929	Belongs to the glycerate kinase type-1 family
C5I45_RS19555	COG1686	Belongs to the peptidase S11 family
C5I45_RS19560	COG0517	IMP dehydrogenase activity
C5I45_RS19560	COG0516	GMP reductase activity
C5I45_RS19595	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C5I45_RS19600	COG0187	DNA topoisomerase II activity
C5I45_RS19615	COG2501	S4 domain
C5I45_RS19620	COG0592	DNA-directed DNA polymerase activity