locus-tag class description QX56_RS00005 ENOG4105CI4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity) QX56_RS00010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) QX56_RS00015 ENOG410848D S4 domain protein YaaA QX56_RS00030 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) QX56_RS00035 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) QX56_RS00070 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) QX56_RS00080 ENOG4105CD9 Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity) QX56_RS00085 ENOG4108UHX Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity) QX56_RS00090 ENOG4105CGR Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity) QX56_RS00100 ENOG4105ZMH deoxynucleoside kinase QX56_RS00110 ENOG4105VRS hydrolase family 18 QX56_RS00115 ENOG4105GTG Isochorismatase QX56_RS00120 ENOG4108Z6B deaminase QX56_RS00125 ENOG4105C6E dna polymerase iii QX56_RS00130 ENOG410816I Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity) QX56_RS00135 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) QX56_RS00145 ENOG41067KS pro-sigma K processing QX56_RS00185 ENOG4105CDW Resistance protein QX56_RS00190 ENOG4105CXN decarboxylase QX56_RS00195 ENOG4108ZMD Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity) QX56_RS00200 ENOG4105X0R protein from nitrogen regulatory protein P-II QX56_RS00205 ENOG4105XVJ Protein of unknown function (DUF327) QX56_RS00210 ENOG4105FA2 dna polymerase iii QX56_RS00215 ENOG4105MA4 psp1 domain protein QX56_RS00220 ENOG4105QD5 Involved in initiation control of chromosome replication (By similarity) QX56_RS00225 ENOG41060K3 Methyltransferase QX56_RS00230 ENOG4105VC4 domain protein QX56_RS00235 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) QX56_RS00240 ENOG4105KRN Transcriptional regulator, abrb family QX56_RS00245 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) QX56_RS00250 ENOG4105F8V Hydrolase, tatD family QX56_RS00255 ENOG41069ER domain protein QX56_RS00265 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) QX56_RS00270 ENOG4105XFA sporulation peptidase YabG QX56_RS00275 ENOG4105W42 Veg protein QX56_RS00280 ENOG4105XEW small acid-soluble spore protein QX56_RS00285 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) QX56_RS00290 ENOG4105DFT pur operon repressor QX56_RS00295 ENOG4105KME endoribonuclease L-psp QX56_RS00300 ENOG4105K4W Could be involved in septation (By similarity) QX56_RS00305 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) QX56_RS00310 ENOG4105C5T Phosphoribosyl pyrophosphate synthase QX56_RS00315 ENOG4105KW6 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity) QX56_RS00320 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) QX56_RS00330 ENOG4108JA2 transcriptioN-repair coupling factor QX56_RS00335 ENOG4108M14 stage v sporulation protein t QX56_RS00345 ENOG4108IY2 MazG family QX56_RS00350 ENOG41082I2 s4 domain protein QX56_RS00355 ENOG4105VYY sporulation protein yabp QX56_RS00370 ENOG41060GV RNA binding s1 domain protein QX56_RS00400 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) QX56_RS00405 ENOG4108UGV hypoxanthine phosphoribosyltransferase QX56_RS00410 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) QX56_RS00420 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) QX56_RS00425 ENOG4107U48 ppic-type peptidyL-prolyl cis-trans isomerase QX56_RS00430 ENOG4105C6T cysteine synthase QX56_RS00435 ENOG4105CRQ synthase (Component I) QX56_RS00440 ENOG4105DDQ anthranilate synthase QX56_RS00445 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 QX56_RS00450 ENOG4105EEI dihydropteroate synthase QX56_RS00455 ENOG4105KRF dihydroneopterin aldolase QX56_RS00460 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase QX56_RS00470 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) QX56_RS00475 ENOG4105CRK lysyL-tRNA synthetase QX56_RS00560 ENOG4108Z0C Uvrb UvrC protein QX56_RS00565 ENOG41066A3 ATP guanido phosphotransferase QX56_RS00575 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) QX56_RS00580 ENOG4105E59 Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity) QX56_RS00585 ENOG4105CTP PilT protein domain protein QX56_RS00590 ENOG4105CE5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) QX56_RS00595 ENOG4108UH8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity) QX56_RS00600 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) QX56_RS00610 ENOG4105D7W serine acetyltransferase QX56_RS00615 ENOG4105C8N cysteinyl-tRNA synthetase QX56_RS00620 ENOG4105KEB Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) QX56_RS00625 ENOG4105C2N RNA methyltransferase TrmH family group 3 QX56_RS00630 ENOG4105M0M Tetracycline resistance protein QX56_RS00645 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) QX56_RS00660 ENOG4108VZM 50s ribosomal protein L10 QX56_RS00670 ENOG4107Y49 methyltransferase QX56_RS00675 ENOG4108IIJ DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) QX56_RS00680 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) QX56_RS00685 ENOG4105XPM ribosomal protein QX56_RS00690 ENOG4108UKE Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity) QX56_RS00695 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) QX56_RS00700 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) QX56_RS00705 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) QX56_RS00710 ENOG4107SKW Inherit from COG: Alpha beta hydrolase QX56_RS00715 ENOG4108Z10 Involved in the binding of tRNA to the ribosomes (By similarity) QX56_RS00720 ENOG4105EEE One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity) QX56_RS00725 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) QX56_RS00735 ENOG4105CFD One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity QX56_RS00750 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) QX56_RS00755 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) QX56_RS00765 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal QX56_RS00770 ENOG4108UNN Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity) QX56_RS00780 ENOG4105CW6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits QX56_RS00790 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) QX56_RS00795 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) QX56_RS00800 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) QX56_RS00805 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) QX56_RS00815 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) QX56_RS00820 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) QX56_RS00830 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) QX56_RS00845 ENOG41067V7 50S ribosomal protein L36 QX56_RS00850 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits QX56_RS00855 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) QX56_RS00860 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) QX56_RS00865 ENOG4108ZT0 50S ribosomal protein l17 QX56_RS00870 ENOG4108JJB ABC transporter QX56_RS00875 ENOG4108JJB ABC transporter QX56_RS00880 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) QX56_RS00885 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) QX56_RS00890 ENOG4108UM5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity) QX56_RS00895 ENOG4108UJD 30S ribosomal protein S9 QX56_RS00900 ENOG4108I0C methyltransferase QX56_RS00915 ENOG4105D1F ATP-binding protein QX56_RS00930 ENOG4108NMV polysaccharide deacetylase QX56_RS01010 ENOG4105CHH sulfate transporter QX56_RS01020 ENOG4108SA1 esterase QX56_RS01040 ENOG410874W AraC family transcriptional regulator QX56_RS01045 ENOG4105EHZ conserved protein UCP016719 QX56_RS01050 ENOG4105D17 glycoside hydrolase, family 3 domain protein QX56_RS01070 ENOG4105E15 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate QX56_RS01080 ENOG4105EWC Purine nucleoside phosphorylase QX56_RS01110 ENOG4105EMN RNA polymerase sigma factor QX56_RS01120 ENOG4105C8B TIGR00159 family QX56_RS01125 ENOG4107U5W ybbr family QX56_RS01130 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) QX56_RS01135 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) QX56_RS01140 ENOG4105D03 DNA-3-methyladenine glycosylase II QX56_RS01150 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) QX56_RS01155 ENOG4108TWJ NADH dehydrogenase subunit 5 QX56_RS01175 ENOG4105GPN Uncharacterized conserved protein (DUF2294) QX56_RS01180 ENOG4105WAB arsR family transcriptional regulator QX56_RS01185 ENOG4108RWP Major Facilitator Superfamily protein QX56_RS01200 ENOG4107ZBH radical SAM domain protein QX56_RS01205 ENOG41066N6 Abortive infection protein QX56_RS01210 ENOG4108WUZ (ABC) transporter QX56_RS01250 ENOG4105G0J serine threonine protein kinase QX56_RS01260 ENOG4106K80 QX56_RS01270 ENOG4106DDH Sporulation-specific SASP protein QX56_RS01280 ENOG4108HWY Beta-lactamase QX56_RS01285 ENOG4107E6A Cytochrome p-450 QX56_RS01295 ENOG4107QTZ amino acid QX56_RS01300 ENOG4107VXM glycerophosphoryl diester phosphodiesterase QX56_RS01305 ENOG4105CXY transporter QX56_RS01315 ENOG410645S MarR family Transcriptional regulator QX56_RS01320 ENOG4105DCM major facilitator superfamily QX56_RS01335 ENOG410631K Membrane QX56_RS01340 ENOG4106AXJ AraC family transcriptional regulator QX56_RS01345 ENOG4108HH9 Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR QX56_RS01350 ENOG4108TCS Glutamyl endopeptidase QX56_RS01360 ENOG4108WC5 Alpha Beta Hydrolase Fold protein QX56_RS01365 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase QX56_RS01370 ENOG4107ZTW SNARE associated Golgi QX56_RS01395 ENOG4105C72 UPF0176 protein QX56_RS01405 ENOG4108IIZ The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane QX56_RS01410 ENOG4105CKA Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity) QX56_RS01425 ENOG4105CM2 brancheD-chain amino acid aminotransferase QX56_RS01430 ENOG4108IQI permease QX56_RS01435 ENOG4108J5H Homocysteine s-methyltransferase QX56_RS01450 ENOG4105CSV Glutaminase QX56_RS01465 ENOG4105UVJ 5-dehydro-4-deoxyglucarate dehydratase QX56_RS01470 ENOG4105C26 Dehydrogenase QX56_RS01475 ENOG4105DJB Major Facilitator Superfamily QX56_RS01480 ENOG4105EQX glucarate dehydratase QX56_RS01485 ENOG41073TP transcriptional regulator QX56_RS01490 ENOG4105CTX dehydratase QX56_RS01505 ENOG4106UX7 integral membrane protein QX56_RS01510 ENOG4105DPZ Two component transcriptional regulator (Winged helix family QX56_RS01540 ENOG4105MUA Resistance protein QX56_RS01545 ENOG4105DGI Alkaline phosphatase QX56_RS01550 ENOG41067S4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) QX56_RS01555 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) QX56_RS01560 ENOG4108KN7 Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity) QX56_RS01565 ENOG4107EPV Aminotransferase class V QX56_RS01570 ENOG4105C0R drug resistance transporter emrb qaca subfamily QX56_RS01575 ENOG4105J7D transcriptional regulator QX56_RS01580 ENOG4107RB3 L-asparaginase QX56_RS01585 ENOG4108KTS Acetyltransferase and hydrolase with the alpha beta hydrolase fold QX56_RS01595 ENOG41060AI SEC-C motif QX56_RS01605 ENOG4107Y7X LytTR QX56_RS01610 ENOG4108IUW ABC transporter QX56_RS01615 ENOG4108SDH ABC, transporter QX56_RS01620 ENOG4107SET aldo keto reductase QX56_RS01650 ENOG4105H9W Short-chain dehydrogenase reductase Sdr QX56_RS01660 ENOG4105DSE periplasmic solute binding protein QX56_RS01665 ENOG4105DIK (ABC) transporter QX56_RS01675 ENOG4105DEN Luciferase family QX56_RS01680 ENOG4108N0M stress protein QX56_RS01685 ENOG4106FN3 tellurium resistance protein QX56_RS01690 ENOG4106FN3 tellurium resistance protein QX56_RS01695 ENOG4107TS3 membrane protein, TerC QX56_RS01700 ENOG4108TTB tellurium resistance protein QX56_RS01710 ENOG41079KZ Major Facilitator Superfamily QX56_RS01715 ENOG4107XZQ multidrug resistance protein QX56_RS01720 ENOG4108A65 Transcriptional regulator QX56_RS01725 ENOG4108IJ7 Glycine betaine QX56_RS01730 ENOG4107SQ8 Glycine betaine QX56_RS01760 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) QX56_RS01795 ENOG4105EIG urea carboxylase-associated protein 1 QX56_RS01800 ENOG4107RA1 nh(3)-dependent nad( ) synthetase QX56_RS01805 ENOG4105I1F Resistance protein QX56_RS01810 ENOG4107Z3Y Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) QX56_RS01815 ENOG41089UC methyltransferase, type 11 QX56_RS01820 ENOG4105C5Q Transcriptional regulator QX56_RS01825 ENOG4105I82 acetyl xylan esterase QX56_RS01830 ENOG410756H nucleotidyltransferase QX56_RS01840 ENOG4105C26 Dehydrogenase QX56_RS01845 ENOG4105CK7 Sodium proline symporter QX56_RS01850 ENOG4107YHD transcriptional regulator QX56_RS01860 ENOG4108PJD permease QX56_RS01865 ENOG4105U6C Alpha beta hydrolase fold protein QX56_RS01875 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) QX56_RS01880 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit QX56_RS01885 ENOG4108IFG nitrite reductase, (NAD(P)H) QX56_RS01890 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) QX56_RS01910 ENOG4105S7A ErfK ybiS ycfS ynhG family protein QX56_RS01915 ENOG4105CKI cobalamin synthesis protein QX56_RS01920 ENOG4105E5Q amino acid AbC transporter QX56_RS01925 ENOG4107XKZ Amino acid ABC superfamily ATP binding cassette transporter binding protein QX56_RS01930 ENOG4105HHM rdd domain containing protein QX56_RS01940 ENOG4105CS2 ec 3.2.1.21 QX56_RS01955 ENOG4105C8Q Methyl-accepting chemotaxis QX56_RS01960 ENOG41080HJ 6-phospho 3-hexuloisomerase QX56_RS01965 ENOG4108VA3 3-hexulose-6-phosphate synthase QX56_RS01970 ENOG4105KVH Transcriptional regulator QX56_RS01975 ENOG4105CEY Amp-dependent synthetase and ligase QX56_RS02005 ENOG4105SX7 Transporter QX56_RS02025 ENOG4105CDA abc transporter atp-binding protein QX56_RS02030 ENOG4105DRP amino acid AbC transporter QX56_RS02040 ENOG4106P55 Transcriptional regulator QX56_RS02045 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase QX56_RS02050 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) QX56_RS02055 ENOG41069ZX QX56_RS02060 ENOG41069ZX QX56_RS02070 ENOG4105DUX Transporter QX56_RS02085 ENOG4105E1K spore germination protein QX56_RS02105 ENOG4107WD8 ABC transporter, permease QX56_RS02110 ENOG4105CK6 Two component transcriptional regulator (Winged helix family QX56_RS02115 ENOG4105BZU Histidine kinase QX56_RS02140 ENOG4105CFH Aspartokinase QX56_RS02145 ENOG4105DHS permease protein QX56_RS02150 ENOG4105CM4 permease protein QX56_RS02155 ENOG4108IPW abc transporter atp-binding protein QX56_RS02170 ENOG4105R8C Transcriptional regulator QX56_RS02175 ENOG4108DBC nitroreductase QX56_RS02180 ENOG41067V3 Antibiotic biosynthesis monooxygenase QX56_RS02185 ENOG4105YVS arsR family transcriptional regulator QX56_RS02195 ENOG4108JPW Aminotransferase QX56_RS02200 ENOG4105C26 Dehydrogenase QX56_RS02210 ENOG4105H9W Short-chain dehydrogenase reductase Sdr QX56_RS02215 ENOG4105KTB nuclear export factor GLE1 QX56_RS02220 ENOG4108T5E Copper resistance protein QX56_RS02225 ENOG4108ZYE Transcriptional regulator QX56_RS02250 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) QX56_RS02255 ENOG4108ZX0 Signal peptidase I QX56_RS02275 ENOG4105E7W lamb ycsf family protein QX56_RS02280 ENOG4105C5A transporter QX56_RS02285 ENOG4105CFM UPF0317 protein QX56_RS02290 ENOG4105P4J Allophanate hydrolase, subunit 1 QX56_RS02300 ENOG4107258 Transcriptional regulator QX56_RS02305 ENOG4105XJB lipolytic protein G-D-S-L family QX56_RS02315 ENOG41061CK Antibiotic biosynthesis monooxygenase QX56_RS02320 ENOG4107RVG penicillin-binding protein QX56_RS02325 ENOG4107QM2 Aldo Keto reductase QX56_RS02330 ENOG4105ETD TRANSCRIPTIONal QX56_RS02340 ENOG4105HMZ Methyltransferase QX56_RS02345 ENOG4105CYX Short-chain dehydrogenase reductase Sdr QX56_RS02360 ENOG410606W general stress protein QX56_RS02370 ENOG4105VCH membrane QX56_RS02380 ENOG4105C9U ATP-dependent DNA helicase RecQ QX56_RS02395 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) QX56_RS02400 ENOG4107R8N Glycosyl transferase, family 2 QX56_RS02410 ENOG4105C0X amino acid QX56_RS02435 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) QX56_RS02445 ENOG4105NRR Uncharacterized protein conserved in bacteria (DUF2188) QX56_RS02450 ENOG4105EU9 QX56_RS02455 ENOG4105QVS general stress protein QX56_RS02460 ENOG41082W1 Cupin 2, conserved barrel domain protein QX56_RS02475 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit QX56_RS02480 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism QX56_RS02485 ENOG4108MRH transcriptional regulatory protein QX56_RS02490 ENOG4107QJT sodium dicarboxylate symporter QX56_RS02495 ENOG4106F5Q Membrane QX56_RS02500 ENOG4105CJ1 ABC, transporter QX56_RS02515 ENOG4105FDT acyl-CoA dehydrogenase QX56_RS02525 ENOG4105SZ6 Thioredoxin QX56_RS02530 ENOG4105CPF Cell wall formation (By similarity) QX56_RS02535 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) QX56_RS02540 ENOG4105C1J atp-dependent rna helicase QX56_RS02545 ENOG410905X membrane-flanked domain protein QX56_RS02550 ENOG4105CKV Membrane QX56_RS02560 ENOG41082V8 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity) QX56_RS02565 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein QX56_RS02570 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) QX56_RS02580 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) QX56_RS02585 ENOG4107MMM Anti-sigma-factor antagonist QX56_RS02590 ENOG4105FUA antagonist QX56_RS02595 ENOG4105QD0 anti-sigma regulatory factor serine threonine protein kinase QX56_RS02600 ENOG4107SGM protein serine threonine phosphatase QX56_RS02605 ENOG4105WN5 stage II sporulation protein QX56_RS02610 ENOG4108ZBE Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity) QX56_RS02620 ENOG41064BQ Phosphatase QX56_RS02625 ENOG4105M5P UPF0310 protein QX56_RS02630 ENOG4105RV9 Transcriptional regulator QX56_RS02680 ENOG4105EYG tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity) QX56_RS02685 ENOG41068WC Domain of unknown function (DUF955) QX56_RS02690 ENOG4108IMY Transcriptional regulator QX56_RS02710 ENOG4108RYM conjugative transposon protein QX56_RS02715 ENOG4106BHR ftsk SpoIIIE family protein QX56_RS02720 ENOG4106128 DNA-binding helix-turn-helix protein QX56_RS02760 ENOG4105P1M Domain of unknown function (DUF1874) QX56_RS02770 ENOG4105K4H Nlp p60 protein QX56_RS02785 ENOG4108U3J QX56_RS02795 ENOG41078D9 QX56_RS02800 ENOG4105DEN Luciferase family QX56_RS02815 ENOG4108W2Y isochorismatase QX56_RS02820 ENOG4105IGJ Zn-dependent Hydrolase of the beta-lactamase fold protein QX56_RS02825 ENOG4108HH4 Major Facilitator Superfamily QX56_RS02845 ENOG4108V4B ThiJ pfpI QX56_RS02850 ENOG4105VEQ Cold shock protein QX56_RS02855 ENOG4108VJ1 Transcriptional regulator (CarD family QX56_RS02865 ENOG4108MCI Transcriptional regulator, ARAC family QX56_RS02870 ENOG4108UZ3 Transporter QX56_RS02875 ENOG41086D8 Transcriptional regulator QX56_RS02880 ENOG4107U9B transcriptional regulator QX56_RS02885 ENOG4105DXI Major Facilitator superfamily QX56_RS02895 ENOG4105CZ9 Domain of unknown function (DU1801) QX56_RS02900 ENOG4105GIG QX56_RS02905 ENOG4105T38 integral membrane protein QX56_RS02910 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family QX56_RS02915 ENOG4108ZMQ domain protein QX56_RS02920 ENOG4105MJ9 esterase QX56_RS02925 ENOG4107Z6X Transcriptional regulator QX56_RS02935 ENOG4105KVH Transcriptional regulator QX56_RS02940 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein QX56_RS02945 ENOG4105EQ0 Major Facilitator superfamily QX56_RS02950 ENOG4108JGH Tetr family transcriptional regulator QX56_RS02955 ENOG41082YX Transcriptional regulator, arsr family QX56_RS02960 ENOG4107R5R arsenical pump membrane protein QX56_RS02965 ENOG4105Z7P Acetyltransferase (GNAT) family QX56_RS02970 ENOG4107Y9U Membrane QX56_RS02980 ENOG4108SQ9 flavin reductase domain protein, FMN-binding QX56_RS02985 ENOG4108ZHR arsR family transcriptional regulator QX56_RS02990 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) QX56_RS03000 ENOG4105ENE Histidine kinase QX56_RS03005 ENOG4108VB1 regulatoR QX56_RS03010 ENOG4105EYF MMPL domain protein QX56_RS03015 ENOG4108WC5 Alpha Beta Hydrolase Fold protein QX56_RS03020 ENOG4108UQV Membrane QX56_RS03025 ENOG4108Z5V transcriptional regulator, merr family QX56_RS03030 ENOG41076HS cation diffusion facilitator family transporter QX56_RS03035 ENOG4108TVJ Nitroreductase QX56_RS03040 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase QX56_RS03045 ENOG4108VGI doxx family QX56_RS03050 ENOG4105XXY Thioredoxin QX56_RS03065 ENOG410900G Protein of unknown function (DUF421) QX56_RS03070 ENOG4108QY0 Membrane QX56_RS03090 ENOG4105PF9 Transcriptional regulator QX56_RS03100 ENOG4105WQG acetyltransferase QX56_RS03110 ENOG4105C85 amino acid QX56_RS03120 ENOG41062A4 Transcriptional regulator QX56_RS03125 ENOG4105EYF MMPL domain protein QX56_RS03130 ENOG4108TVJ Nitroreductase QX56_RS03135 ENOG4105FS7 Transcriptional regulator QX56_RS03140 ENOG4105C2C drug resistance transporter, Bcr CflA QX56_RS03150 ENOG4105DRR Transcriptional regulator, GntR family QX56_RS03155 ENOG4105VRS hydrolase family 18 QX56_RS03170 ENOG4105G6Z alkaline phosphatase QX56_RS03175 ENOG4108ZMX Domain of unknown function (DU1801) QX56_RS03185 ENOG4108YM7 Gcn5-related n-acetyltransferase QX56_RS03190 ENOG4107TVP HD domain protein QX56_RS03195 ENOG41090UD (LipO)protein QX56_RS03200 ENOG4105F27 Major Facilitator QX56_RS03205 ENOG4105VZJ PTS System QX56_RS03210 ENOG4105VCP PTS System QX56_RS03215 ENOG4105CK1 PTS System QX56_RS03220 ENOG4105CS2 ec 3.2.1.21 QX56_RS03225 ENOG4108TZY GntR Family Transcriptional Regulator QX56_RS03230 ENOG4105EVU fructokinase QX56_RS03240 ENOG4105D3P Mannan endo-1,4-beta-mannosidase QX56_RS03285 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) QX56_RS03290 ENOG4105K8N protein family UPF0079, ATPase QX56_RS03295 ENOG41072GX Peptidase M22 Glycoprotease QX56_RS03300 ENOG410801F ribosomal-protein-alanine acetyltransferase QX56_RS03305 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) QX56_RS03310 ENOG4105C5H ABC transporter QX56_RS03315 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) QX56_RS03320 ENOG4105FF6 Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity) QX56_RS03325 ENOG41067S4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) QX56_RS03330 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) QX56_RS03340 ENOG4108TYN CAAX amino terminal protease family protein QX56_RS03350 ENOG4105CJ9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity) QX56_RS03375 ENOG4105DVF Cytosine-specific methyltransferase QX56_RS03380 ENOG4107RHI Cytosine-specific methyltransferase QX56_RS03420 ENOG4105PGZ NB-ARC domain QX56_RS03425 ENOG4105CPQ Dehydrogenase QX56_RS03430 ENOG4105CT4 transporter QX56_RS03440 ENOG41087YS Phage shock protein A QX56_RS03445 ENOG4105DQX Zinc finger domain QX56_RS03450 ENOG4108WV1 Pfam:DUF477 QX56_RS03460 ENOG4108ZMR Ion transport 2 domain-containing protein QX56_RS03465 ENOG4107QNK )-transporter QX56_RS03495 ENOG4107YUH hydrolase QX56_RS03505 ENOG4107STQ Multicopper oxidase QX56_RS03510 ENOG4105C85 amino acid QX56_RS03520 ENOG4105C7R Atpase associated with various cellular activities aaa_3 QX56_RS03540 ENOG4105C7N Xanthine uracil vitamin C permease QX56_RS03560 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) QX56_RS03565 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit QX56_RS03570 ENOG4105C83 adenylosuccinate lyase QX56_RS03575 ENOG4105C8V SAICAR synthetase QX56_RS03580 ENOG4105VR9 phosphoribosylformylglycinamidine synthase QX56_RS03585 ENOG4105D21 Phosphoribosylformylglycinamidine synthase I QX56_RS03590 ENOG4108JIU phosphoribosylformylglycinamidine synthase ii QX56_RS03600 ENOG4105CXB phosphoribosylaminoimidazole synthetase QX56_RS03605 ENOG4108V3E phosphoribosylglycinamide formyltransferase QX56_RS03610 ENOG4105DC1 bifunctional purine biosynthesis protein purh QX56_RS03615 ENOG4105C12 Phosphoribosylglycinamide synthetase QX56_RS03625 ENOG4105DVH amino acid QX56_RS03640 ENOG4108R5T secreted protein QX56_RS03645 ENOG4105KGF protein, YerC YecD QX56_RS03650 ENOG4105CBC glutamate synthase QX56_RS03655 ENOG4108RTE 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales (By similarity) QX56_RS03660 ENOG4105C4R Atp-dependent dna helicase QX56_RS03665 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) QX56_RS03675 ENOG4105CRN Aminoglycoside phosphotransferase QX56_RS03680 ENOG4105KT7 mgtC SapB transporter QX56_RS03685 ENOG4105CK7 Sodium proline symporter QX56_RS03690 ENOG4105VB5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) QX56_RS03695 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) QX56_RS03700 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) QX56_RS03705 ENOG4108IG5 Transcriptional regulator QX56_RS03715 ENOG4105CBD Diacylglycerol kinase QX56_RS03720 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) QX56_RS03735 ENOG4105D85 methylase QX56_RS03740 ENOG4105F6A helicase QX56_RS03745 ENOG4105ECI YeeC-like protein QX56_RS03785 ENOG4105CDY transcriptional regulatory protein QX56_RS03795 ENOG4105M4P Tetr family transcriptional regulator QX56_RS03800 ENOG41062KD Inherit from COG: ketosteroid isomerase-like protein QX56_RS03805 ENOG4107S9F NmrA family QX56_RS03820 ENOG4105WEF catalase QX56_RS03825 ENOG4105M18 -acetyltransferase QX56_RS03840 ENOG4105C2F Histidine kinase QX56_RS03845 ENOG4105EQD regulatoR QX56_RS03850 ENOG410769Z extracellular solute-binding protein family 1 QX56_RS03855 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component QX56_RS03860 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component QX56_RS03865 ENOG4105F5H Glycosyl Hydrolase Family 88 QX56_RS03870 ENOG41075H3 AraC family transcriptional regulator QX56_RS03875 ENOG4107TDE lipolytic protein G-D-S-L family QX56_RS03890 ENOG4105CX8 fg-gap repeat protein QX56_RS03895 ENOG4105CX8 fg-gap repeat protein QX56_RS03900 ENOG4107TDE lipolytic protein G-D-S-L family QX56_RS03910 ENOG4105EKC QX56_RS03915 ENOG4105E0S extracellular solute-binding protein family 1 QX56_RS03925 ENOG4105C50 Binding-protein-dependent transport systems, inner membrane component QX56_RS03930 ENOG4105F8D glycoside hydrolase family 4 QX56_RS03935 ENOG4105H67 Protein of unknown function (DUF421) QX56_RS03940 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) QX56_RS03945 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily QX56_RS03960 ENOG4106I4J membrane QX56_RS03965 ENOG4108PCN EamA-like transporter family QX56_RS03970 ENOG41082F9 transcriptional regulator QX56_RS03975 ENOG41061H0 Monooxygenase QX56_RS03980 ENOG4108R1P QX56_RS03985 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) QX56_RS03990 ENOG4105E0M Sulfatase QX56_RS03995 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase QX56_RS04005 ENOG41090R9 glycosyltransferase QX56_RS04010 ENOG4107R51 Glycosyl transferase, family 2 QX56_RS04015 ENOG41090R9 glycosyltransferase QX56_RS04020 ENOG4105EU0 Major facilitator Superfamily QX56_RS04030 ENOG4105CUB amino acid QX56_RS04035 ENOG4105C26 Dehydrogenase QX56_RS04040 ENOG4105FKZ Methyl-accepting chemotaxis QX56_RS04045 ENOG4105C5H ABC transporter QX56_RS04055 ENOG4107SWG transcriptional regulator MERR family QX56_RS04060 ENOG4105DXB Major Facilitator superfamily QX56_RS04070 ENOG4105C5H ABC transporter QX56_RS04075 ENOG4105FDU atp-dependent rna helicase QX56_RS04085 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein QX56_RS04100 ENOG4105E6M Sulphatase-modifying factor protein QX56_RS04105 ENOG4105E0A ABC, transporter QX56_RS04110 ENOG4108U1V ABC transporter, permease QX56_RS04115 ENOG4105DQ5 transport system permease protein QX56_RS04120 ENOG4108HUF Transporter QX56_RS04135 ENOG4108J20 pectate lyase QX56_RS04140 ENOG4107QPK )-transporter QX56_RS04150 ENOG4108MRH transcriptional regulatory protein QX56_RS04175 ENOG410855V Acylphosphatase QX56_RS04180 ENOG4108RPX mosc domain containing protein QX56_RS04190 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) QX56_RS04215 ENOG4105GEU Spore germination protein QX56_RS04225 ENOG4108Q5U germination protein, ger(x)c family QX56_RS04230 ENOG4105E1K spore germination protein QX56_RS04235 ENOG4105C5Y PTS System QX56_RS04240 ENOG4105CG3 alpha amylase, catalytic region QX56_RS04245 ENOG4107414 GntR family transcriptional regulator QX56_RS04250 ENOG4108RCM Nitroreductase QX56_RS04255 ENOG4105CGH 5'-nucleotidase QX56_RS04260 ENOG4107RKG DJ-1/PfpI family QX56_RS04275 ENOG4105KJF protein tyrosine phosphatase QX56_RS04285 ENOG4107U9T Pfam:Ribonuclease_BN QX56_RS04290 ENOG4108ISG Major Facilitator QX56_RS04295 ENOG4105UPD Calcium Proton QX56_RS04305 ENOG4105D8X mechanosensitive ion channel QX56_RS04325 ENOG4106KE4 Dehydrogenase QX56_RS04330 ENOG4105D7N magnesium and cobalt transport protein CorA QX56_RS04340 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) QX56_RS04365 ENOG4107RUY (E1 component), alpha subunit QX56_RS04375 ENOG4107QKR Dehydrogenase QX56_RS04385 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family QX56_RS04390 ENOG41069DP small acid-soluble spore protein QX56_RS04395 ENOG4105KK4 UPF0060 membrane protein QX56_RS04425 ENOG4105F8D glycoside hydrolase family 4 QX56_RS04430 ENOG4108Q3X Transcriptional regulator QX56_RS04435 ENOG4105CI1 PTS System QX56_RS04440 ENOG4105BZ1 (ABC) transporter QX56_RS04445 ENOG4105BZ1 (ABC) transporter QX56_RS04455 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase QX56_RS04460 ENOG4105ID8 Transcriptional regulator, ARAC family QX56_RS04470 ENOG4107QP6 Xylose isomerase domain protein TIM barrel QX56_RS04475 ENOG4105CIB oxidoreductase Domain protein QX56_RS04480 ENOG4105BZU Histidine kinase QX56_RS04485 ENOG4105WH1 Two component transcriptional regulator luxr family QX56_RS04490 ENOG4105CJ1 ABC, transporter QX56_RS04495 ENOG41090VJ ABC-2 type transporter QX56_RS04500 ENOG4108KYE ABC-2 type transporter QX56_RS04505 ENOG4105U3E Transcriptional regulator QX56_RS04510 ENOG4108KTS Acetyltransferase and hydrolase with the alpha beta hydrolase fold QX56_RS04515 ENOG4105H93 Acyltransferase family QX56_RS04520 ENOG4105YA8 Transcriptional regulator QX56_RS04525 ENOG4107Y80 Major Facilitator superfamily QX56_RS04530 ENOG4108YYS metal-dependent hydrolase (By similarity) QX56_RS04535 ENOG4105C0R drug resistance transporter emrb qaca subfamily QX56_RS04540 ENOG410834F Transcriptional regulator QX56_RS04550 ENOG4108MES Periplasmic binding protein QX56_RS04555 ENOG4105DQ5 transport system permease protein QX56_RS04560 ENOG4108IHU transport system permease protein QX56_RS04565 ENOG4105JAB phenazine biosynthesis protein, phzf family QX56_RS04570 ENOG4107Y03 Nitroreductase QX56_RS04580 ENOG4105ECP epimerase QX56_RS04595 ENOG4105F27 Major Facilitator QX56_RS04615 ENOG4106AKJ QX56_RS04620 ENOG4105D74 hydrolase QX56_RS04625 ENOG4105CKK Glycosyl transferase, family 2 QX56_RS04630 ENOG4105EJV Membrane QX56_RS04635 ENOG41067AE Membrane-bound metal-dependent hydrolase QX56_RS04640 ENOG4105CEN a g-specific adenine glycosylase QX56_RS04645 ENOG4106BXE QX56_RS04650 ENOG4105CAN Short-chain dehydrogenase reductase Sdr QX56_RS04665 ENOG4105EVI UPF0374 protein QX56_RS04670 ENOG4105BZ1 (ABC) transporter QX56_RS04675 ENOG4107NBY Membrane QX56_RS04685 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen QX56_RS04690 ENOG4105G5W regulator Fur family QX56_RS04800 ENOG4108N23 SpoOM-related protein QX56_RS04810 ENOG4105EC3 peptidase S51, dipeptidase E QX56_RS04815 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) QX56_RS04820 ENOG4105DNP FAD linked oxidase domain protein QX56_RS04835 ENOG4105E2Y ABC, transporter QX56_RS04840 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein QX56_RS04845 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component QX56_RS04850 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) QX56_RS04860 ENOG4105VBI Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity) QX56_RS04865 ENOG4107D63 QX56_RS04870 ENOG4105VZ8 Transcriptional regulator QX56_RS04885 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) QX56_RS04895 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) QX56_RS04915 ENOG4105CYN Serine protein kinase QX56_RS04920 ENOG4106AKX UPF0229 protein QX56_RS04925 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes QX56_RS04930 ENOG4105CW7 secretion protein, HlyD family QX56_RS04935 ENOG4105C0R drug resistance transporter emrb qaca subfamily QX56_RS04940 ENOG4105CS1 NAD(P)H quinone oxidoreductase QX56_RS04955 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family QX56_RS04960 ENOG4105CZV ABC transporter QX56_RS04965 ENOG4105CJ1 ABC, transporter QX56_RS04970 ENOG4108TU7 Inherit from COG: (ABC) transporter QX56_RS04975 ENOG4105VEQ Cold shock protein QX56_RS04990 ENOG4105BZU Histidine kinase QX56_RS05030 ENOG4108YBP pseudouridine synthase QX56_RS05040 ENOG41080XP Cbs domain QX56_RS05045 ENOG4107YBY Hydrolase QX56_RS05050 ENOG4105DGM nitrilase cyanide hydratase and apolipoprotein n-acyltransferase QX56_RS05055 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) QX56_RS05060 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator QX56_RS05070 ENOG4108HMR Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) QX56_RS05075 ENOG4105C6V Glycerol-3-phosphate dehydrogenase QX56_RS05085 ENOG4105BZU Histidine kinase QX56_RS05090 ENOG4105WH1 Two component transcriptional regulator luxr family QX56_RS05125 ENOG4105ED1 spovr family QX56_RS05130 ENOG4105G6Z alkaline phosphatase QX56_RS05145 ENOG4105BZN citrate synthase QX56_RS05150 ENOG4105CYX Short-chain dehydrogenase reductase Sdr QX56_RS05155 ENOG4105CUB amino acid QX56_RS05160 ENOG4105C8J )-transporter QX56_RS05165 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family QX56_RS05180 ENOG4105J37 QX56_RS05185 ENOG4108AEY RNA polymerase sigma factor QX56_RS05190 ENOG4108FN7 Aldo keto reductase QX56_RS05195 ENOG4105F6E Acyl-transferase QX56_RS05200 ENOG4105C37 (CBS) domain QX56_RS05210 ENOG4105CHM Aminotransferase QX56_RS05215 ENOG4105C37 (CBS) domain QX56_RS05225 ENOG4105WMR Protein CrcB homolog QX56_RS05230 ENOG4108QXE glycerophosphoryl diester phosphodiesterase QX56_RS05235 ENOG4105D64 Mechanosensitive ion channel QX56_RS05240 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) QX56_RS05245 ENOG4107VMI polysaccharide deacetylase QX56_RS05250 ENOG4105F0I Aminotransferase QX56_RS05265 ENOG4105BZ1 (ABC) transporter QX56_RS05270 ENOG4105BZ1 (ABC) transporter QX56_RS05290 ENOG410839P QX56_RS05300 ENOG4106MP8 UPF0754 membrane protein QX56_RS05305 ENOG4105WZB UPF0342 protein QX56_RS05310 ENOG4105F1N DNA alkylation repair QX56_RS05320 ENOG4105D4P Coproporphyrinogen iii oxidase QX56_RS05325 ENOG4107S91 Sodium hydrogen exchanger QX56_RS05330 ENOG4105NCW Trka-c domain protein QX56_RS05340 ENOG4105CGU Enoyl-CoA hydratase QX56_RS05350 ENOG4108IUX (ABC) transporter QX56_RS05355 ENOG4105RHA ABC transporter, permease QX56_RS05360 ENOG4107VRP DNA repair exonuclease QX56_RS05365 ENOG4106D4I domain protein QX56_RS05370 ENOG4105EQI Metal Dependent Phosphohydrolase QX56_RS05380 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) QX56_RS05420 ENOG4105NBU tryptophan transport protein QX56_RS05425 ENOG4105DXJ Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) QX56_RS05430 ENOG4105K59 histidine triad (HIT) protein QX56_RS05465 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation QX56_RS05470 ENOG4105BZ4 penicillin-binding protein QX56_RS05475 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) QX56_RS05480 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) QX56_RS05485 ENOG4105C1Q protoporphyrinogen oxidase QX56_RS05495 ENOG4105ECB domain protein QX56_RS05505 ENOG41090T1 Membrane QX56_RS05515 ENOG4105DER m42 family QX56_RS05530 ENOG4108RQ5 Beta-lactamase domain-containing protein QX56_RS05535 ENOG4105DF9 Lipoate-protein, ligase QX56_RS05545 ENOG4105CEY Amp-dependent synthetase and ligase QX56_RS05555 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 QX56_RS05560 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin QX56_RS05565 ENOG4105KD7 acetyltransferase QX56_RS05575 ENOG4108HUF Transporter QX56_RS05580 ENOG4107TB6 phosphoglycerate mutase QX56_RS05590 ENOG4107F3J Amp-dependent synthetase and ligase QX56_RS05595 ENOG4107ZYJ bioY protein QX56_RS05600 ENOG4106YBV Methyl-accepting chemotaxis QX56_RS05620 ENOG4105XVF Competence transcription factor QX56_RS05625 ENOG4105CYX Short-chain dehydrogenase reductase Sdr QX56_RS05630 ENOG4105X3H Excalibur domain protein QX56_RS05635 ENOG4105E1V na solute symporter QX56_RS05640 ENOG4106CAD Protein of unknown function (DUF3311) QX56_RS05645 ENOG41060YP QX56_RS05660 ENOG4107SCK Monooxygenase QX56_RS05665 ENOG4108INS Transcriptional regulator QX56_RS05680 ENOG4105TRI Hydrolase QX56_RS05695 ENOG4108KK1 membrane protein AbrB duplication QX56_RS05700 ENOG4106K7D Major facilitator family transporter QX56_RS05705 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) QX56_RS05725 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation QX56_RS05735 ENOG4105EYH Exonuclease QX56_RS05785 ENOG4105ERH Fumarylacetoacetate hydrolase QX56_RS05795 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin QX56_RS05805 ENOG4105CAQ asparagine synthetase QX56_RS05820 ENOG4105UQX Mate efflux family protein QX56_RS05825 ENOG4106HBX Transcriptional Regulator AraC Family QX56_RS05830 ENOG4105ETE Transcriptional regulator (LacI family QX56_RS05835 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) QX56_RS05840 ENOG4105SF0 DinB family QX56_RS05845 ENOG4108ZUB Lysine exporter protein (Lyse ygga) QX56_RS05850 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family QX56_RS05855 ENOG4105MYW Pentapeptide repeat protein QX56_RS05860 ENOG4107S9D Alpha beta hydrolase QX56_RS05865 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) QX56_RS05870 ENOG4107RIQ Sulfate adenylate transferase QX56_RS05875 ENOG4105ET3 Reduction of activated sulfate into sulfite (By similarity) QX56_RS05880 ENOG4108N5B 2-phosphosulfolactate phosphatase QX56_RS05885 ENOG41061P3 phosphosulfolactate synthase QX56_RS05895 ENOG4105DIA mandelate racemase muconate lactonizing QX56_RS05900 ENOG4107RCC Major Facilitator Superfamily QX56_RS05905 ENOG4108SZE gCN5-related N-acetyltransferase QX56_RS05910 ENOG4105MA6 gCN5-related N-acetyltransferase QX56_RS05920 ENOG4108VPT UPF0234 protein QX56_RS05925 ENOG4105QNR S1 RNA binding domain protein QX56_RS05945 ENOG4105K7K Transcriptional regulator QX56_RS05955 ENOG410751J QX56_RS05960 ENOG4105D4Y metalloprotease QX56_RS05965 ENOG4105EPR degv family QX56_RS05970 ENOG4107AYK membrAne QX56_RS05980 ENOG41073B9 QX56_RS05985 ENOG4108KP7 hydrolase QX56_RS05990 ENOG4108MXZ Esterase QX56_RS05995 ENOG4105VG1 fes assembly suf system protein QX56_RS06000 ENOG4105IQ5 FAD linked oxidase domain protein QX56_RS06010 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase QX56_RS06015 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) QX56_RS06025 ENOG4105C8Y Acetylornithine aminotransferase QX56_RS06030 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain QX56_RS06040 ENOG4105DBV ornithine carbamoyltransferase QX56_RS06065 ENOG4107RMD Basic membrane lipoprotein QX56_RS06080 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) QX56_RS06085 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) QX56_RS06095 ENOG4105C3U ABC transporter QX56_RS06100 ENOG4108JQ7 (ABC) transporter QX56_RS06115 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component QX56_RS06125 ENOG4105C31 Tryptophanyl-tRNA synthetase QX56_RS06130 ENOG4108J59 Extracellular solute-binding protein, family 5 QX56_RS06135 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component QX56_RS06140 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component QX56_RS06150 ENOG4108JQ7 (ABC) transporter QX56_RS06165 ENOG41090SU Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity) QX56_RS06170 ENOG4108ZCF integral membrane protein QX56_RS06175 ENOG4108SQ7 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis QX56_RS06185 ENOG4105DPN Oligoendopeptidase f QX56_RS06195 ENOG4105T58 Dithiol-disulfide isomerase QX56_RS06200 ENOG4108Z18 K06886 hemoglobin QX56_RS06205 ENOG4105E4C Lytic transglycosylase catalytic QX56_RS06210 ENOG4105MIX Adenylate cyclase QX56_RS06225 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) QX56_RS06230 ENOG4105EMS pseudouridine synthase QX56_RS06245 ENOG4105ETU transcriptional activator (TenA QX56_RS06250 ENOG4108VEU Thiamine monophosphate synthase QX56_RS06265 ENOG4105CA8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity) QX56_RS06270 ENOG4105D06 uba thif-type nad fad binding protein QX56_RS06275 ENOG4105DWF phosphomethylpyrimidine kinase QX56_RS06280 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH QX56_RS06285 ENOG4107A88 QX56_RS06335 ENOG4105ENA helicase QX56_RS06350 ENOG4108ZMI UPF0477 protein QX56_RS06360 ENOG4105C28 cystathionine QX56_RS06365 ENOG4105C28 cystathionine QX56_RS06370 ENOG4105D9U N-acetyltransferase QX56_RS06375 ENOG4105JHY Membrane QX56_RS06385 ENOG41068SY QX56_RS06395 ENOG4107KNS QX56_RS06420 ENOG4108PSK reductase QX56_RS06435 ENOG4105DM4 PTS System QX56_RS06440 ENOG4105DG6 mannose-6-phosphate isomerase QX56_RS06445 ENOG4105G7B Protein of unknown function (DUF2992) QX56_RS06450 ENOG4105VMI -acetyltransferase QX56_RS06460 ENOG4108Z66 YbaK ebsC protein QX56_RS06475 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) QX56_RS06485 ENOG4108ZJ4 polysaccharide deacetylase QX56_RS06490 ENOG4107CUJ Protein of unknown function (DUF2690) QX56_RS06510 ENOG4108IEG Formate dehydrogenase Alpha subunit QX56_RS06535 ENOG4106A3M Cytochrome p-450 QX56_RS06540 ENOG41087PP glycosyltransferase MGT family QX56_RS06550 ENOG4105EXQ uroporphyrinogen iii synthase hem4 QX56_RS06555 ENOG4105C4B ABC transporter, permease QX56_RS06560 ENOG4108IXI (ABC) transporter QX56_RS06570 ENOG4105Q95 Cupin 2, conserved barrel domain protein QX56_RS06585 ENOG4105D2H Uronic isomerase QX56_RS06590 ENOG4105CT4 transporter QX56_RS06595 ENOG4105DG4 malate L-lactate dehydrogenase QX56_RS06600 ENOG4105CPQ Dehydrogenase QX56_RS06605 ENOG4105CHZ Catalyzes the dehydration of D-mannonate (By similarity) QX56_RS06610 ENOG4105DMW Dehydrogenase reductase QX56_RS06615 ENOG4108I5G Major Facilitator superfamily QX56_RS06620 ENOG4107KJX Transcriptional regulator QX56_RS06625 ENOG4107QZW Altronate oxidoreductase QX56_RS06630 ENOG4105CTX dehydratase QX56_RS06635 ENOG4107TSN permease QX56_RS06645 ENOG4105JD4 ATPase yjob QX56_RS06660 ENOG41068K0 YCII-related domain QX56_RS06665 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase QX56_RS06670 ENOG4105KWG Pfam:DUF1696 QX56_RS06675 ENOG4105K7W phage-related replication protein QX56_RS06680 ENOG4105WEF catalase QX56_RS06685 ENOG410635T phage-like element pbsx protein QX56_RS06725 ENOG4108TFU terminase (Small subunit) QX56_RS06730 ENOG4105IG6 Phage terminase, large subunit QX56_RS06735 ENOG4108MDF Phage Portal Protein QX56_RS06760 ENOG41060SN QX56_RS06775 ENOG4105PQS phage protein QX56_RS06780 ENOG4105FR7 XkdM protein, phage-like element PBSX QX56_RS06785 ENOG4105MTC XkdN-like protein QX56_RS06790 ENOG4108FKH Transglycosylase SLT domain QX56_RS06795 ENOG4108WZM domain protein QX56_RS06800 ENOG4105X7F QX56_RS06810 ENOG4105MFU Protein of unknown function (DUF2634) QX56_RS06815 ENOG41066EA baseplate J family protein QX56_RS06820 ENOG410906S phage-like element pbsx protein xkdt QX56_RS06830 ENOG41068G1 QX56_RS06860 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase QX56_RS06875 ENOG4105CJ3 phosphate transporter QX56_RS06880 ENOG4107GRR phosphate transport regulator QX56_RS06885 ENOG4107R7I amino acid QX56_RS06895 ENOG4105EDW glycosyl transferase, family 39 QX56_RS06900 ENOG4105CKK Glycosyl transferase, family 2 QX56_RS06905 ENOG4105C0H protease QX56_RS06915 ENOG4108ME1 Peptidase M55 D-aminopeptidase QX56_RS06920 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component QX56_RS06925 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component QX56_RS06930 ENOG4105C3U ABC transporter QX56_RS06940 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A QX56_RS06945 ENOG4105DTQ mandelate racemase muconate lactonizing QX56_RS06950 ENOG4107SN7 NLP P60 protein QX56_RS06955 ENOG4108JQ7 (ABC) transporter QX56_RS06960 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) QX56_RS06965 ENOG4107TUM Amidinotransferase QX56_RS06970 ENOG4108S4H thioesterase Superfamily protein QX56_RS06975 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) QX56_RS06995 ENOG4108428 Inherit from COG: -acetyltransferase QX56_RS07005 ENOG41080TC multidrug resistance protein QX56_RS07010 ENOG4105CIY formyltetrahydrofolate deformylase QX56_RS07015 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) QX56_RS07030 ENOG4105K56 Transcriptional regulator QX56_RS07035 ENOG4108ZHJ Organic hydroperoxide resistance protein QX56_RS07045 ENOG4107Y2X deaminase QX56_RS07050 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) QX56_RS07055 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin QX56_RS07065 ENOG4108W7F transporter, permease QX56_RS07070 ENOG4108JJB ABC transporter QX56_RS07075 ENOG4105NSK ABC superfamily ATP binding cassette transporter membrane protein QX56_RS07080 ENOG4108X43 YKOF domain protein QX56_RS07085 ENOG4105CK6 Two component transcriptional regulator (Winged helix family QX56_RS07090 ENOG41062D9 Histidine kinase QX56_RS07100 ENOG4106849 propeptide, pepSY amd peptidase M4 QX56_RS07110 ENOG4105CJW magnesium transporter QX56_RS07115 ENOG4105V75 Transcriptional regulator QX56_RS07155 ENOG4105DQE DNA ligase QX56_RS07160 ENOG4105FDF Could be involved in DNA repair (By similarity) QX56_RS07170 ENOG4107T5V SNARE associated Golgi QX56_RS07175 ENOG4107TS3 membrane protein, TerC QX56_RS07180 ENOG4108WZW RNA polymerase sigma QX56_RS07190 ENOG410681C small acid-soluble spore protein QX56_RS07200 ENOG4105D0M Protease HtpX homolog QX56_RS07210 ENOG4108TGC Acyltransferase QX56_RS07215 ENOG4105BZU Histidine kinase QX56_RS07220 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) QX56_RS07225 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) QX56_RS07230 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) QX56_RS07235 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase QX56_RS07245 ENOG4107T6J Ribulose-1,5-bisphosphate carboxylase oxygenase large subunit QX56_RS07250 ENOG4105JAS Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene) (By similarity) QX56_RS07255 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) QX56_RS07260 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) QX56_RS07280 ENOG4105BZU Histidine kinase QX56_RS07285 ENOG41090MY MarR family Transcriptional regulator QX56_RS07290 ENOG4105ER2 Ompa motb domain protein QX56_RS07295 ENOG4105E14 MotA TolQ exbB proton channel QX56_RS07305 ENOG4108K88 Membrane QX56_RS07310 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) QX56_RS07315 ENOG4107ZAE 6-carboxy-5,6,7,8-tetrahydropterin synthase QX56_RS07320 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) QX56_RS07325 ENOG4105CSD Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity) QX56_RS07335 ENOG4105CBZ Short-chain dehydrogenase reductase Sdr QX56_RS07340 ENOG4105FEA Spore maturation protein QX56_RS07375 ENOG4105F0V Cell wall hydrolase QX56_RS07390 ENOG4105C59 p-type ATPase QX56_RS07400 ENOG4105DC7 peptidase M24 QX56_RS07410 ENOG4105CID antiterminator QX56_RS07420 ENOG4105KRI phosphocarrier protein (HPr QX56_RS07425 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) QX56_RS07435 ENOG4105F6S Spore photoproduct lyase QX56_RS07445 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer QX56_RS07450 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase QX56_RS07455 ENOG4105K4I Scp-like extracellular QX56_RS07465 ENOG4105BZU Histidine kinase QX56_RS07470 ENOG4105CHM Aminotransferase QX56_RS07475 ENOG4107R88 Chemotaxis protein (CheV) QX56_RS07480 ENOG4105UIN QX56_RS07490 ENOG4107Y2H ErfK ybiS ycfS ynhG family protein QX56_RS07500 ENOG4105K6S Short-chain dehydrogenase reductase Sdr QX56_RS07505 ENOG4105ESF Peptidoglycan binding domain protein QX56_RS07510 ENOG4105ESF Peptidoglycan binding domain protein QX56_RS07520 ENOG4105EPM Diguanylate phosphodiesterase QX56_RS07525 ENOG4107IN1 Protein of unknown function (DUF1797) QX56_RS07530 ENOG4108XRC Protein of unknown function (DUF458) QX56_RS07560 ENOG4105NQC Flavodoxin QX56_RS07570 ENOG4105CH2 amidohydrolase QX56_RS07580 ENOG4105D8X mechanosensitive ion channel QX56_RS07585 ENOG4105D3R alkyl hydroperoxide reductase QX56_RS07590 ENOG4107R19 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen QX56_RS07605 ENOG41082CS Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) QX56_RS07610 ENOG4105D06 uba thif-type nad fad binding protein QX56_RS07615 ENOG4105CVM Molybdenum cofactor synthesis domain protein QX56_RS07620 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein QX56_RS07625 ENOG4108ZAF Molybdopterin QX56_RS07630 ENOG41067WU Molybdopterin converting factor (Subunit 1) QX56_RS07635 ENOG4105BZ1 (ABC) transporter QX56_RS07640 ENOG4105BZ1 (ABC) transporter QX56_RS07650 ENOG4107X8C Efflux transporter RND family MFP subunit QX56_RS07655 ENOG4105C19 ABC transporter QX56_RS07660 ENOG4107RBB ABC transporter, permease QX56_RS07665 ENOG4105E98 transcriptional regulator DeoR family QX56_RS07670 ENOG4105DE4 1-phosphofructokinase QX56_RS07675 ENOG4105DM4 PTS System QX56_RS07680 ENOG4105C3F Signal peptidase i QX56_RS07690 ENOG4105C5H ABC transporter QX56_RS07695 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) QX56_RS07715 ENOG4105BZU Histidine kinase QX56_RS07725 ENOG4107ZYR domain protein QX56_RS07735 ENOG4105CN5 Metallo-Beta-Lactamase QX56_RS07745 ENOG4108X4Q Hydrolase QX56_RS07750 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) QX56_RS07770 ENOG4105CPP Dehydrogenase, E1 component QX56_RS07775 ENOG4105C7S Dehydrogenase QX56_RS07780 ENOG4107QN2 dihydrolipoyl dehydrogenase QX56_RS07790 ENOG4105CXN decarboxylase QX56_RS07795 ENOG4105WBI UPF0223 protein QX56_RS07810 ENOG4105ECY inositol monophosphatase QX56_RS07820 ENOG4105JQZ Methyltransferase QX56_RS07860 ENOG4105CI3 gtp-binding protein typa QX56_RS07865 ENOG4105QA2 QX56_RS07880 ENOG4108IAB Phoh family QX56_RS07890 ENOG4105CSV Glutaminase QX56_RS07895 ENOG4105ZPI UPF0358 protein QX56_RS07900 ENOG4105CNI cell division protein FtsW QX56_RS07905 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) QX56_RS07915 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) QX56_RS07925 ENOG4105BZ9 Cytochrome C oxidase, subunit I QX56_RS07930 ENOG4105CCU oxidase (Subunit III) QX56_RS07935 ENOG41064X9 cytochrome C oxidase subunit IV QX56_RS07950 ENOG41080XQ Signal transduction protein with cbs domains QX56_RS07955 ENOG4106UY4 Inherit from COG: Scp-like extracellular QX56_RS07975 ENOG4105WUC UPF0298 protein QX56_RS07980 ENOG4106H78 methyltransferase QX56_RS07985 ENOG4108ZEF Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity) QX56_RS07990 ENOG4105H20 Sporulation integral membrane protein YlbJ QX56_RS07995 ENOG4105D78 K07001 NTE family protein QX56_RS08000 ENOG41063PX domain protein QX56_RS08005 ENOG4105CDE UPF0348 protein QX56_RS08015 ENOG4105KNH Nucleic acid-binding protein QX56_RS08040 ENOG4108V6E Cell division protein mraZ QX56_RS08045 ENOG4105CGJ Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity) QX56_RS08055 ENOG4105CJN penicillin-binding protein QX56_RS08060 ENOG4105CJN penicillin-binding protein QX56_RS08065 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) QX56_RS08070 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) QX56_RS08075 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) QX56_RS08080 ENOG4105CNI cell division protein FtsW QX56_RS08085 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) QX56_RS08090 ENOG4105D4A Cell wall formation (By similarity) QX56_RS08095 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) QX56_RS08100 ENOG4108R2U division initiation protein QX56_RS08110 ENOG4105K67 small basic protein QX56_RS08115 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) QX56_RS08120 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) QX56_RS08130 ENOG4105FFI sigma-e processing peptidase spoiiga QX56_RS08135 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) QX56_RS08145 ENOG4105DKW ABC transporter QX56_RS08155 ENOG4105WR5 sporulation protein, YlmC YmxH family QX56_RS08160 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase QX56_RS08165 ENOG4105DFA alanine racemase domain protein QX56_RS08170 ENOG4105VR5 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity) QX56_RS08175 ENOG41067XK integral membrane protein QX56_RS08180 ENOG4105DBK s4 domain protein QX56_RS08190 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) QX56_RS08200 ENOG4105M02 This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) QX56_RS08205 ENOG4105C34 Pseudouridine synthase QX56_RS08210 ENOG4108UK1 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity) QX56_RS08220 ENOG4105CXT aspartate transcarbamylase QX56_RS08230 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain QX56_RS08235 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain QX56_RS08240 ENOG4105DF0 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity) QX56_RS08245 ENOG4107RY0 Catalyzes the conversion of dihydroorotate to orotate (By similarity) QX56_RS08250 ENOG4106EG9 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity) QX56_RS08255 ENOG41065E1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) QX56_RS08260 ENOG4105ET3 Reduction of activated sulfate into sulfite (By similarity) QX56_RS08270 ENOG4107S4M Sulfate adenylate transferase QX56_RS08275 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) QX56_RS08280 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) QX56_RS08285 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein QX56_RS08290 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein QX56_RS08305 ENOG4105DSJ YicC domain protein QX56_RS08310 ENOG4105KC4 UPF0296 protein QX56_RS08315 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) QX56_RS08325 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase QX56_RS08330 ENOG4105C25 Primosomal protein n' QX56_RS08335 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) QX56_RS08340 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) QX56_RS08345 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B QX56_RS08350 ENOG4105C55 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs QX56_RS08355 ENOG4108ZF3 Phosphatase QX56_RS08360 ENOG4105D9P serine threonine protein kinase QX56_RS08365 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) QX56_RS08370 ENOG4105DJV ribulose-phosphate 3-epimerase QX56_RS08375 ENOG4105FJ0 thiamine QX56_RS08385 ENOG4105VB9 50S ribosomal protein l28 QX56_RS08390 ENOG4108ZAA Alkaline-shock protein QX56_RS08395 ENOG4105DP4 dak2 domain fusion protein ylov QX56_RS08405 ENOG4105EJQ L-serine dehydratase QX56_RS08410 ENOG4105CB5 ATP-dependent DNA helicase recG QX56_RS08415 ENOG4108VVV Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism (By similarity) QX56_RS08425 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase QX56_RS08430 ENOG4105CHR reductase QX56_RS08440 ENOG4108ZBM Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) QX56_RS08445 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) QX56_RS08450 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) QX56_RS08460 ENOG4105VBN Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity) QX56_RS08470 ENOG4105K5M 30s ribosomal protein S16 QX56_RS08475 ENOG4108BW8 UPF0109 protein QX56_RS08485 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) QX56_RS08490 ENOG4105D6X Specifically methylates guanosine-37 in various tRNAs (By similarity) QX56_RS08495 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) QX56_RS08500 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) QX56_RS08505 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) QX56_RS08515 ENOG4105VM1 flagellar QX56_RS08520 ENOG4105CMV Succinyl-CoA synthetase subunit beta QX56_RS08525 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha QX56_RS08530 ENOG4105C79 DNA protecting protein DprA QX56_RS08535 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) QX56_RS08540 ENOG4107QXI Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity) QX56_RS08545 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) QX56_RS08550 ENOG4108R5P Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity) QX56_RS08555 ENOG4105C4N this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity) QX56_RS08565 ENOG4105Q75 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) QX56_RS08570 ENOG4108ZC9 flagellar basal-body rod protein flgc QX56_RS08575 ENOG4105VQ0 flagellar hook-basal body complex protein fliE QX56_RS08580 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) QX56_RS08585 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) QX56_RS08600 ENOG4106YF4 Flagellar biosynthesis chaperone QX56_RS08610 ENOG410696Y Flagellar hook-length control protein QX56_RS08615 ENOG410822I Flagellar hook capping protein QX56_RS08620 ENOG4108JQA flagellar QX56_RS08625 ENOG41068WV flagellar FlbD family protein QX56_RS08635 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) QX56_RS08640 ENOG4105DD5 Flagellar motor switch protein QX56_RS08645 ENOG4107YTP response regulator receiver protein QX56_RS08655 ENOG4105CN7 Flagellar biosynthetic protein FliP QX56_RS08660 ENOG4105VS8 Flagellar biosynthetic protein fliq QX56_RS08665 ENOG4105D19 Role in flagellar biosynthesis (By similarity) QX56_RS08670 ENOG4105D00 flagellar biosynthetic protein flhB QX56_RS08675 ENOG4105D7B Flagellar biosynthesis protein flha QX56_RS08680 ENOG4105FZW flagellar biosynthesis regulator FlhF QX56_RS08690 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) QX56_RS08695 ENOG4105CBS Chea signal transduction histidine kinase QX56_RS08700 ENOG410807Z Modulation of CheA activity in response to attractants (Chemotaxis QX56_RS08715 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) QX56_RS08725 ENOG4105CE9 30S ribosomal protein S2 QX56_RS08730 ENOG4105CU7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity) QX56_RS08740 ENOG4108VCV Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) QX56_RS08745 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) QX56_RS08750 ENOG4105KNE Phosphatidate cytidylyltransferase QX56_RS08760 ENOG4105DZP Membrane-associated zinc metalloprotease QX56_RS08765 ENOG4105C90 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity) QX56_RS08770 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) QX56_RS08775 ENOG4105K7D Required for maturation of 30S ribosomal subunits (By similarity) QX56_RS08780 ENOG4105CHV Transcription elongation factor NusA QX56_RS08785 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination QX56_RS08790 ENOG4105VHM ribosomal protein QX56_RS08795 ENOG4107EEM One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity) QX56_RS08800 ENOG4105W7A Protein of unknown function (DUF503) QX56_RS08805 ENOG4105KG7 Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity) QX56_RS08810 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) QX56_RS08815 ENOG4105DTN riboflavin biosynthesis protein ribF QX56_RS08820 ENOG4105K77 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity) QX56_RS08825 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) QX56_RS08835 ENOG4105C1V Peptidase, M16 QX56_RS08845 ENOG4105E35 Dipicolinate synthase subunit A QX56_RS08850 ENOG4108S0H Dipicolinic acid synthetase, b subunit QX56_RS08855 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) QX56_RS08865 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) QX56_RS08875 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit QX56_RS08885 ENOG4105CNU cell division protein FtsK QX56_RS08890 ENOG4105FDP GntR family transcriptional regulator QX56_RS08910 ENOG4108RKS Short-chain dehydrogenase reductase Sdr QX56_RS08915 ENOG4105XZV Protein of unknown function (DUF3243) QX56_RS08930 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase QX56_RS08935 ENOG4105CEV competence damage-inducible protein QX56_RS08945 ENOG4108A04 Beta-lactamase QX56_RS08950 ENOG4105E4Y Endoribonuclease that initiates mRNA decay (By similarity) QX56_RS08955 ENOG4105D48 metallophosphoesterase QX56_RS08960 ENOG4105MCT stage V sporulation protein S QX56_RS08970 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) QX56_RS08975 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) QX56_RS08990 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) QX56_RS08995 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) QX56_RS09005 ENOG4105IIP Membrane QX56_RS09010 ENOG4105W1N transcriptional regulator QX56_RS09015 ENOG4108151 Beta-lactamase domain protein QX56_RS09025 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase QX56_RS09035 ENOG4107QKG PfaD family QX56_RS09040 ENOG41062T2 Acyl carrier protein QX56_RS09045 ENOG4108MH3 Polyketide beta-ketoacyl acyl carrier protein synthase QX56_RS09050 ENOG4105F99 Hydroxymethylglutaryl-CoA synthase QX56_RS09055 ENOG4108MGH Enoyl-CoA hydratase QX56_RS09060 ENOG4108KQ6 Enoyl-CoA hydratase QX56_RS09065 ENOG4105C0W non-ribosomal peptide synthetase QX56_RS09070 ENOG4107SQU synthase QX56_RS09090 ENOG4106A3M Cytochrome p-450 QX56_RS09105 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin QX56_RS09110 ENOG4105K7W phage-related replication protein QX56_RS09115 ENOG4108X3M OsmC Ohr family protein QX56_RS09120 ENOG410814C multidrug resistance protein QX56_RS09140 ENOG4105DKX Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity) QX56_RS09145 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) QX56_RS09160 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) QX56_RS09165 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) QX56_RS09170 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) QX56_RS09175 ENOG4105U6W MutT NUDIX family protein QX56_RS09180 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase QX56_RS09185 ENOG4106F1P AAA ATPase, central domain protein QX56_RS09190 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) QX56_RS09195 ENOG4105CXI aluminum resistance protein QX56_RS09200 ENOG4105KV4 Transcriptional regulator QX56_RS09205 ENOG4105C5F glutamine synthetase QX56_RS09210 ENOG41079P0 QX56_RS09230 ENOG4107AUC QX56_RS09260 ENOG410907G QX56_RS09265 ENOG4105CT4 transporter QX56_RS09270 ENOG4105DSG hydrolase family 43 QX56_RS09275 ENOG4105E2R ROK family QX56_RS09280 ENOG4105C93 Xylose Isomerase QX56_RS09285 ENOG4105CMG Carbohydrate kinase QX56_RS09290 ENOG4107Y9E nuclease QX56_RS09295 ENOG4105C54 Major Facilitator superfamily QX56_RS09300 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) QX56_RS09310 ENOG4107YUK This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) QX56_RS09320 ENOG4105C0V Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity) QX56_RS09370 ENOG4108Q8B Spore germination protein QX56_RS09375 ENOG4108NHD germination protein QX56_RS09390 ENOG4105FVX QX56_RS09400 ENOG4105K7W phage-related replication protein QX56_RS09410 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) QX56_RS09415 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) QX56_RS09425 ENOG4108SVB resolvase QX56_RS09430 ENOG4105VPS UPF0291 protein QX56_RS09435 ENOG4105CV1 Transketolase (EC 2.2.1.1) QX56_RS09455 ENOG4107QIV Cytochrome c biogenesis protein QX56_RS09480 ENOG4107DZX Small, acid-soluble spore protein P QX56_RS09490 ENOG4108I0Z Aconitate hydratase QX56_RS09495 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen QX56_RS09505 ENOG41067CD Small, acid-soluble spore protein Tlp QX56_RS09515 ENOG4105MI2 QX56_RS09520 ENOG4105W8X HesB YadR YfhF-family protein QX56_RS09525 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) QX56_RS09530 ENOG4105K4P CoA-binding domain protein QX56_RS09535 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) QX56_RS09555 ENOG4107QWR cellulase (EC 3.2.1.4) QX56_RS09565 ENOG4108MYR Secreted protein QX56_RS09570 ENOG4107SYN Glycosyl hydrolases family 43 QX56_RS09580 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase QX56_RS09585 ENOG4107T5V SNARE associated Golgi QX56_RS09595 ENOG4107QX3 carboxylase QX56_RS09600 ENOG4105E39 Enoyl-CoA hydratase QX56_RS09605 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase QX56_RS09610 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit QX56_RS09615 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase QX56_RS09620 ENOG4105CEY Amp-dependent synthetase and ligase QX56_RS09625 ENOG4105C1G acyl-Coa dehydrogenase QX56_RS09635 ENOG4105F32 YngK protein QX56_RS09640 ENOG4106U2H Protein of unknown function (DUF1360) QX56_RS09650 ENOG4105CEY Amp-dependent synthetase and ligase QX56_RS09655 ENOG4105C0W non-ribosomal peptide synthetase QX56_RS09665 ENOG4105C0W non-ribosomal peptide synthetase QX56_RS09670 ENOG4107RVU D-Ala-D-Ala carboxypeptidase 3 (S13) family QX56_RS09675 ENOG4108N2V aldose 1-epimerase QX56_RS09680 ENOG4107QJQ Mate efflux family protein QX56_RS09705 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) QX56_RS09710 ENOG4105SKE transcriptional Regulator LysR family QX56_RS09715 ENOG4105CB2 alcohol dehydrogenase QX56_RS09720 ENOG4105BZ8 glutamate synthase QX56_RS09725 ENOG4105CBC glutamate synthase QX56_RS09730 ENOG4105C5Q Transcriptional regulator QX56_RS09735 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) QX56_RS09740 ENOG4105II7 pyrroline-5-carboxylate reductase QX56_RS09760 ENOG4108UB7 QX56_RS09765 ENOG41068WN QX56_RS09770 ENOG4105IE8 Alpha-ketoglutarate permease QX56_RS09775 ENOG4107U6E carbohydrate kinase FGGY QX56_RS09780 ENOG4108M3J Dehydrogenase QX56_RS09785 ENOG4108J2R molybdopterin oxidoreductase QX56_RS09810 ENOG4105EC8 Methyl-accepting chemotaxis QX56_RS09820 ENOG4108YQE rare lipoprotein a QX56_RS09825 ENOG4105XPP Protein of unknown function (DUF1275) QX56_RS09830 ENOG4108NR7 pectate lyase QX56_RS09835 ENOG4108RAV Conserved protein QX56_RS09845 ENOG4105F0F Oxalate decarboxylase QX56_RS09855 ENOG4105EPI acetyltransferase, (GNAT) family QX56_RS09870 ENOG41073R8 VanW family QX56_RS09880 ENOG4105VMP Transcriptional regulator QX56_RS09885 ENOG4105NX3 Membrane QX56_RS09895 ENOG4108Q5Y Membrane QX56_RS09905 ENOG4108V4B ThiJ pfpI QX56_RS09910 ENOG4108J4B Beta-lactamase QX56_RS09930 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) QX56_RS09935 ENOG4107T94 Endo-14-beta-xylanase QX56_RS09940 ENOG4105YB8 TM2 domain containing protein QX56_RS09945 ENOG4108IMY Transcriptional regulator QX56_RS09960 ENOG4108RAV Conserved protein QX56_RS09965 ENOG41079CX QX56_RS09980 ENOG410780I phosphoprotein phosphatase activity QX56_RS10010 ENOG4105DB4 QX56_RS10025 ENOG4106ANW SMI1_KNR4 QX56_RS10030 ENOG4106BHF QX56_RS10050 ENOG4108Z7R Chaperone CsaA QX56_RS10055 ENOG4105FTV AraC Family Transcriptional Regulator QX56_RS10060 ENOG4108HJF gCN5-related N-acetyltransferase QX56_RS10070 ENOG4108W8B Beta-lactamase domain protein QX56_RS10080 ENOG4105D29 Helix-turn-helix type 11 domain protein QX56_RS10090 ENOG4105KTU Transcriptional regulator, arsr family QX56_RS10100 ENOG4108SJC Membrane QX56_RS10120 ENOG4105ECK Fatty Acid Desaturase QX56_RS10125 ENOG4108ZGX Histidine kinase QX56_RS10130 ENOG4108S01 response regulator QX56_RS10135 ENOG41069ER domain protein QX56_RS10140 ENOG4105C9U ATP-dependent DNA helicase RecQ QX56_RS10145 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) QX56_RS10150 ENOG4105SCY DNAK suppressor QX56_RS10190 ENOG4105C26 Dehydrogenase QX56_RS10195 ENOG4105EWU Squalene--hopene cyclase QX56_RS10200 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) QX56_RS10205 ENOG4105C8J )-transporter QX56_RS10210 ENOG4105C09 Bile acid QX56_RS10215 ENOG4105C7S Dehydrogenase QX56_RS10225 ENOG4107T89 von Willebrand factor, type A QX56_RS10230 ENOG4105GMT ATPase associated with various cellular activities aaa_5 QX56_RS10240 ENOG4105K4H Nlp p60 protein QX56_RS10245 ENOG41087PP glycosyltransferase MGT family QX56_RS10255 ENOG4107QMU Mate efflux family protein QX56_RS10260 ENOG4106SCS STAS domain QX56_RS10280 ENOG4105FR1 rard protein QX56_RS10295 ENOG4105C6Z Gluconate QX56_RS10300 ENOG41090U3 tautomerase QX56_RS10315 ENOG4105FBA Phospholipase Carboxylesterase QX56_RS10330 ENOG4105E1V na solute symporter QX56_RS10350 ENOG4108VXD carboxy-peptidase QX56_RS10355 ENOG4105D3A purine nucleoside phosphorylase DeoD-type QX56_RS10360 ENOG4106Z5R QX56_RS10365 ENOG410841Q phosphoesterase PA-phosphatase related protein QX56_RS10390 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein QX56_RS10395 ENOG4108TSC N-acetyltransferase QX56_RS10400 ENOG4107S4Y M20 DapE family protein YgeY QX56_RS10415 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) QX56_RS10450 ENOG4107T32 3-phytase (EC 3.1.3.8) QX56_RS10455 ENOG4105C5E polysaccharide biosynthesis protein QX56_RS10460 ENOG4106Y37 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity) QX56_RS10525 ENOG4105FTQ Dna gyrase QX56_RS10530 ENOG4107YUK This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) QX56_RS10535 ENOG4106ITI Glutaredoxin QX56_RS10560 ENOG4107S45 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) QX56_RS10565 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) QX56_RS10640 ENOG4105DVF Cytosine-specific methyltransferase QX56_RS10645 ENOG4106210 phosphatase activity QX56_RS10670 ENOG4106J9J DNA polymerase QX56_RS10680 ENOG4106IVX QX56_RS10685 ENOG4106PTB DnaB-like helicase C terminal domain QX56_RS10695 ENOG41088HM QX56_RS10700 ENOG4106YR8 QX56_RS10730 ENOG4105K7W phage-related replication protein QX56_RS10745 ENOG4108RAV Conserved protein QX56_RS10750 ENOG4108J9Q DNA ligase QX56_RS10795 ENOG4105GJD protein, conserved in bacteria QX56_RS10820 ENOG4108ZUE Phage regulatory protein rha QX56_RS10910 ENOG4107D0N QX56_RS10925 ENOG4106HHG QX56_RS10950 ENOG4106J6E QX56_RS10955 ENOG4107NTZ QX56_RS10960 ENOG41063R6 QX56_RS10970 ENOG4108NE4 QX56_RS10985 ENOG41067QW Transcriptional regulator QX56_RS10995 ENOG4105ZUG QX56_RS11000 ENOG4105K70 DNA-binding protein QX56_RS11010 ENOG4106QVS QX56_RS11105 ENOG41068G1 QX56_RS11160 ENOG4105E4C Lytic transglycosylase catalytic QX56_RS11180 ENOG4108HQ0 Exopolysaccharide biosynthesis protein QX56_RS11185 ENOG4105MYH QX56_RS11195 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase QX56_RS11215 ENOG4107R0E Glycosyl transferase, family 2 QX56_RS11240 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) QX56_RS11265 ENOG4105UA4 acetyltransferase QX56_RS11275 ENOG41090AA QX56_RS11280 ENOG4106BHF QX56_RS11295 ENOG4107Y9E nuclease QX56_RS11305 ENOG4108AQF aminoglycoside N(3)-acetyltransferase QX56_RS11310 ENOG4106RPI QX56_RS11325 ENOG4105C5E polysaccharide biosynthesis protein QX56_RS11330 ENOG4105E0X reductase QX56_RS11335 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) QX56_RS11355 ENOG4105QZP Uncharacterized protein conserved in bacteria (DUF2140) QX56_RS11360 ENOG41090WU lipolytic protein G-D-S-L family QX56_RS11365 ENOG4108KF3 Electron transport protein SCO1 SenC QX56_RS11375 ENOG4105C7B Threonine dehydratase QX56_RS11385 ENOG4108UT2 hemolysin iii QX56_RS11395 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) QX56_RS11400 ENOG4105C0V Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity) QX56_RS11415 ENOG4107YX5 Pfam:DUF548 QX56_RS11420 ENOG4108Y6J UPF0403 protein QX56_RS11425 ENOG4105C01 Dihydroxy-acid dehydratase QX56_RS11440 ENOG4108V06 Glutathione peroxidase QX56_RS11445 ENOG4105CVG Homoserine O-transsuccinylase QX56_RS11485 ENOG41081VK Ribonuclease QX56_RS11505 ENOG410890F Dynamin family QX56_RS11515 ENOG41065KQ synthase QX56_RS11520 ENOG4105C2W permease QX56_RS11525 ENOG4108UPS Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity) QX56_RS11530 ENOG4105CTD carboxy-peptidase QX56_RS11535 ENOG4105CAX The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity) QX56_RS11540 ENOG4108UHU Aldolase QX56_RS11545 ENOG4105D7K pfkb domain protein QX56_RS11550 ENOG4108M60 Transcriptional regulator QX56_RS11560 ENOG4105CHR reductase QX56_RS11565 ENOG4105DVT helicase QX56_RS11575 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) QX56_RS11585 ENOG4108UKS UPF0398 protein QX56_RS11590 ENOG4107X2U Inherit from COG: Exonuclease-like protein QX56_RS11595 ENOG4108I5C dEAD DEAH box helicase QX56_RS11645 ENOG4105BZ4 penicillin-binding protein QX56_RS11655 ENOG4105CSM endonuclease III QX56_RS11665 ENOG4105C5S asparaginyl-tRNA synthetase QX56_RS11670 ENOG4105CHM Aminotransferase QX56_RS11680 ENOG4105DVT helicase QX56_RS11685 ENOG4108Z2X Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity) QX56_RS11690 ENOG4108IAA Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity) QX56_RS11695 ENOG4105CCG Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity) QX56_RS11710 ENOG4105CPK Glycosyl transferase (Group 1 QX56_RS11715 ENOG4105FJR Lmbe family QX56_RS11720 ENOG4108Z5K methylglyoxal synthase QX56_RS11725 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) QX56_RS11730 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase QX56_RS11735 ENOG4108JYZ YitT family QX56_RS11755 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) QX56_RS11775 ENOG41068YB TPR repeat-containing protein QX56_RS11780 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase QX56_RS11790 ENOG4105CIH Imidazole acetol-phosphate transaminase QX56_RS11800 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) QX56_RS11805 ENOG4108ZGB N-(5'-phosphoribosyl)anthranilate isomerase QX56_RS11815 ENOG4108I0Q anthranilate phosphoribosyltransferase QX56_RS11820 ENOG4105CRQ synthase (Component I) QX56_RS11825 ENOG4105KHN chorismate mutase QX56_RS11830 ENOG4105D49 3-dehydroquinate synthase QX56_RS11835 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase QX56_RS11840 ENOG4105BZU Histidine kinase QX56_RS11845 ENOG4108UGX Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity) QX56_RS11850 ENOG4105EAH synthase QX56_RS11855 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) QX56_RS11860 ENOG4105XXQ heptaprenyl diphosphate synthase component I QX56_RS11870 ENOG4105EUJ GTP cyclohydrolase i QX56_RS11875 ENOG4105K70 DNA-binding protein QX56_RS11880 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) QX56_RS11895 ENOG4105CSF NADPH-dependent glycerol-3-phosphate dehydrogenase QX56_RS11900 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) QX56_RS11905 ENOG41065D1 QX56_RS11910 ENOG4105S2F QX56_RS11920 ENOG4106UJV Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity) QX56_RS11925 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) QX56_RS11930 ENOG4105CAT Cytidine monophosphate kinase QX56_RS11940 ENOG4105MSI germination protein ypeb QX56_RS11950 ENOG4108PNU Involved in the degradation of specific anti-sigma factors (By similarity) QX56_RS11955 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase QX56_RS11970 ENOG4107RGJ metallophosphoesterase QX56_RS11985 ENOG4105I7S Abortive infection protein QX56_RS11990 ENOG4105C9U ATP-dependent DNA helicase RecQ QX56_RS11995 ENOG4105T7X QX56_RS12005 ENOG4108SAX Membrane QX56_RS12010 ENOG4108JQ1 Dehydrogenase QX56_RS12015 ENOG4105FF2 Type I DHQase QX56_RS12030 ENOG4105BZU Histidine kinase QX56_RS12035 ENOG4105CK6 Two component transcriptional regulator (Winged helix family QX56_RS12040 ENOG4105CRE cytochrome C QX56_RS12045 ENOG4107TWT Cytochrome c biogenesis protein QX56_RS12055 ENOG4105FE9 pseudouridine synthase QX56_RS12065 ENOG4108JIC nucleoside recognition domain protein QX56_RS12070 ENOG4105DZ1 carboxypeptidase QX56_RS12080 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) QX56_RS12085 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) QX56_RS12100 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) QX56_RS12105 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) QX56_RS12110 ENOG4108R6K riboflavin synthase, subunit alpha QX56_RS12115 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) QX56_RS12125 ENOG4105C3F Signal peptidase i QX56_RS12130 ENOG4105VES Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) QX56_RS12150 ENOG4107ZE5 PPIases accelerate the folding of proteins QX56_RS12155 ENOG4105PTM secreted protein QX56_RS12160 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) QX56_RS12170 ENOG4105G6R Stage v sporulation protein ae QX56_RS12180 ENOG4105CZ3 stage V sporulation protein ad QX56_RS12185 ENOG41090VF Stage v sporulation protein ac QX56_RS12200 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) QX56_RS12205 ENOG4108ZBE Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity) QX56_RS12210 ENOG41082AN stage II sporulation protein QX56_RS12215 ENOG4105DZ1 carboxypeptidase QX56_RS12220 ENOG4105CB1 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) QX56_RS12225 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) QX56_RS12230 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) QX56_RS12240 ENOG4105I3K Ferric uptake regulator, Fur family QX56_RS12245 ENOG4105MZ9 stage II sporulation protein m QX56_RS12260 ENOG4105DFD Na H antiporter QX56_RS12265 ENOG4108IJ0 Aspartate ammonia-lyase QX56_RS12270 ENOG4105HDK L-asparaginase QX56_RS12275 ENOG4108IMY Transcriptional regulator QX56_RS12285 ENOG4108YZ4 nudix hydrolase QX56_RS12295 ENOG4105CPC Aldo Keto reductase QX56_RS12315 ENOG4106HZJ QX56_RS12320 ENOG4105RHY Pfam:UPF0157 QX56_RS12325 ENOG4105KAC Antibiotic biosynthesis monooxygenase QX56_RS12330 ENOG4108XET gCN5-related N-acetyltransferase QX56_RS12340 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) QX56_RS12350 ENOG4105E5W Transporter QX56_RS12355 ENOG4105HRU Glyoxalase Bleomycin resistance protein (Dioxygenase QX56_RS12370 ENOG4108IXY short-chain dehydrogenase reductase QX56_RS12375 ENOG41069FQ Metallo-beta-lactamase superfamily QX56_RS12380 ENOG4105II7 pyrroline-5-carboxylate reductase QX56_RS12390 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase QX56_RS12400 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) QX56_RS12405 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase QX56_RS12410 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) QX56_RS12415 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) QX56_RS12425 ENOG4107XQC Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity) QX56_RS12430 ENOG4108NA0 Uncharacterized conserved protein (COG2071) QX56_RS12435 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) QX56_RS12440 ENOG4108HNZ carboxyl transferase QX56_RS12445 ENOG4108ZVT methylmalonyl-coA epimerase QX56_RS12450 ENOG4108VZI ErfK ybiS ycfS ynhG family protein QX56_RS12455 ENOG4108QEG Membrane QX56_RS12460 ENOG4105CDA abc transporter atp-binding protein QX56_RS12465 ENOG4105E5Q amino acid AbC transporter QX56_RS12470 ENOG4108HW3 (ABC) transporter QX56_RS12475 ENOG4108Y6J UPF0403 protein QX56_RS12480 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) QX56_RS12495 ENOG4105C7S Dehydrogenase QX56_RS12500 ENOG4105CPP Dehydrogenase, E1 component QX56_RS12515 ENOG4105CKM Branched-chain carboxylic acid kinase QX56_RS12520 ENOG4107RDP Dehydrogenase QX56_RS12530 ENOG4108JUB Transcriptional regulator QX56_RS12535 ENOG4106CCJ Protein of unknown function (DUF2627) QX56_RS12540 ENOG4105CR4 methylisocitrate lyase QX56_RS12545 ENOG4105DXD 2-methylcitrate dehydratase QX56_RS12555 ENOG4105C1G acyl-Coa dehydrogenase QX56_RS12560 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase QX56_RS12570 ENOG4108QXE glycerophosphoryl diester phosphodiesterase QX56_RS12575 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase QX56_RS12585 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase QX56_RS12590 ENOG4107QQR Sporulation QX56_RS12595 ENOG4105S1Z Stage IV sporulation protein B QX56_RS12600 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) QX56_RS12605 ENOG4105XBY Regulates arginine biosynthesis genes (By similarity) QX56_RS12610 ENOG4105DX0 Hemolysin A QX56_RS12620 ENOG4105CTB Polyprenyl synthetase QX56_RS12625 ENOG41067QG Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) QX56_RS12630 ENOG4105DVS Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) QX56_RS12635 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) QX56_RS12640 ENOG4105M7K Involved in the transcription termination process (By similarity) QX56_RS12645 ENOG4108ZSR alkaline shock protein QX56_RS12650 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase QX56_RS12670 ENOG410644B Stage III sporulation protein af QX56_RS12680 ENOG4105KQ4 Stage iii sporulation protein ad QX56_RS12685 ENOG4108CQH stage III sporulation protein AC QX56_RS12690 ENOG4105KR5 Stage iii sporulation protein QX56_RS12695 ENOG4105CD2 stage iii sporulation protein aa QX56_RS12705 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) QX56_RS12710 ENOG4105DC7 peptidase M24 QX56_RS12715 ENOG4108Z38 Catalyzes a trans-dehydration via an enolate intermediate (By similarity) QX56_RS12725 ENOG4105CBJ Metal-dependent enzyme QX56_RS12740 ENOG4105KST dependent repressor QX56_RS12745 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) QX56_RS12750 ENOG4105WZW rhodanese family QX56_RS12755 ENOG4107RGW The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor QX56_RS12760 ENOG4107QK8 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor QX56_RS12765 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) QX56_RS12770 ENOG4105C0D helicase QX56_RS12785 ENOG4108IMY Transcriptional regulator QX56_RS12795 ENOG4105VFR signal peptidase QX56_RS12855 ENOG4105C37 (CBS) domain QX56_RS12880 ENOG4105C5X domain protein QX56_RS12905 ENOG4105E0M Sulfatase QX56_RS12920 ENOG4107ZXI Rhomboid family QX56_RS12925 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase QX56_RS12950 ENOG41068DG YceG-like family QX56_RS12955 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) QX56_RS12960 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) QX56_RS12965 ENOG4105E2Z phosphate ABC transporter (Permease QX56_RS12970 ENOG4105C8U phosphate abc transporter QX56_RS12975 ENOG4105CVA phosphate QX56_RS12980 ENOG4107RF6 penicillin-binding protein QX56_RS12990 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) QX56_RS12995 ENOG4105SXS Protein of unknown function (DUF456) QX56_RS13015 ENOG4105C4E Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity) QX56_RS13020 ENOG41063Y9 QX56_RS13025 ENOG4108U5J '-nucleotidase QX56_RS13030 ENOG4105N80 Ferric uptake regulator, Fur family QX56_RS13035 ENOG4108JYZ YitT family QX56_RS13040 ENOG41069ZM Protein of unknown function (DUF2624) QX56_RS13045 ENOG4105EFU Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity) QX56_RS13060 ENOG4108IUH Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity) QX56_RS13065 ENOG4105EGD dinuclear metal center protein, YbgI family QX56_RS13080 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) QX56_RS13085 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) QX56_RS13090 ENOG41082VT Uncharacterized BCR, YaiI/YqxD family COG1671 QX56_RS13095 ENOG4105CF9 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity) QX56_RS13105 ENOG4105C38 Glycyl-tRNA synthetase beta subunit QX56_RS13110 ENOG4108HMW glycyl-tRNA synthetase, alpha subunit QX56_RS13115 ENOG4106DBE Involved in DNA repair and RecF pathway recombination (By similarity) QX56_RS13120 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) QX56_RS13125 ENOG4105KG3 cytidine deaminase QX56_RS13130 ENOG4107YR5 Diacylglycerol kinase QX56_RS13135 ENOG4105KGE Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity) QX56_RS13140 ENOG4105CTJ Metal Dependent Phosphohydrolase QX56_RS13145 ENOG4105C9A Phoh family QX56_RS13150 ENOG4105EI1 sporulation protein yqfd QX56_RS13155 ENOG41068P3 sporulation protein YqfC QX56_RS13165 ENOG4105DI5 UPF0365 protein QX56_RS13170 ENOG4105F7J membrane-bound serine protease QX56_RS13175 ENOG4105KTH gatB Yqey QX56_RS13190 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) QX56_RS13195 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) QX56_RS13200 ENOG4105F59 Methylates ribosomal protein L11 (By similarity) QX56_RS13210 ENOG4105CFG Acts as a chaperone (By similarity) QX56_RS13215 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ QX56_RS13220 ENOG4105CI8 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity) QX56_RS13225 ENOG4105CSA Coproporphyrinogen iii oxidase QX56_RS13230 ENOG4105C4S Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity) QX56_RS13240 ENOG4108ZRV stage ii sporulation protein p QX56_RS13245 ENOG4105CEF Initiates the rapid degradation of small, acid-soluble proteins during spore germination (By similarity) QX56_RS13250 ENOG41082YS Binds directly to 16S ribosomal RNA QX56_RS13255 ENOG4105TQK DNA polymerase iii, delta' subunit QX56_RS13265 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 QX56_RS13270 ENOG4108UK2 deaminase QX56_RS13275 ENOG4105KQC Competence protein QX56_RS13285 ENOG4108D32 Methyltransferase QX56_RS13295 ENOG4108WF2 Metal Dependent Phosphohydrolase QX56_RS13300 ENOG4108Z1W Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity) QX56_RS13305 ENOG410812S Rna-binding protein QX56_RS13310 ENOG4105E2X shikimate dehydrogenase QX56_RS13315 ENOG4105CQW ribosome biogenesis GTPase YqeH QX56_RS13320 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase QX56_RS13335 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase QX56_RS13340 ENOG41080BT SNARE associated Golgi QX56_RS13355 ENOG4105WFK nuclease QX56_RS13365 ENOG4107Y5K Resolvase QX56_RS13370 ENOG4108UXE Protein tyrosine phosphatase QX56_RS13375 ENOG4105D6J arsenicaL-resistance protein QX56_RS13380 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase QX56_RS13385 ENOG41085FC arsR family transcriptional regulator QX56_RS13410 ENOG41064HX Suppressor of fused protein (SUFU) QX56_RS13425 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase QX56_RS13460 ENOG410906S phage-like element pbsx protein xkdt QX56_RS13465 ENOG41066EA baseplate J family protein QX56_RS13470 ENOG4105MFU Protein of unknown function (DUF2634) QX56_RS13480 ENOG4105X7F QX56_RS13485 ENOG4108WZM domain protein QX56_RS13490 ENOG4108FKH Transglycosylase SLT domain QX56_RS13495 ENOG4105MTC XkdN-like protein QX56_RS13505 ENOG4105FR7 XkdM protein, phage-like element PBSX QX56_RS13510 ENOG4105PQS phage protein QX56_RS13525 ENOG41060SN QX56_RS13560 ENOG4106CGH Phage Mu protein F like protein QX56_RS13565 ENOG4108MDF Phage Portal Protein QX56_RS13570 ENOG4105IG6 Phage terminase, large subunit QX56_RS13590 ENOG4106129 QX56_RS13600 ENOG4105QBX endodeoxyribonuclease RusA QX56_RS13615 ENOG4108PNI recT protein QX56_RS13620 ENOG4108NF7 phage-type endonuclease QX56_RS13640 ENOG4106A7E Transcriptional regulator QX56_RS13645 ENOG41067QW Transcriptional regulator QX56_RS13650 ENOG4105KR8 Inherit from COG: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) QX56_RS13670 ENOG4108SWU Histidine kinase QX56_RS13675 ENOG4105DPZ Two component transcriptional regulator (Winged helix family QX56_RS13680 ENOG4105DHF Membrane QX56_RS13685 ENOG4108UYN gCN5-related N-acetyltransferase QX56_RS13690 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein QX56_RS13695 ENOG41068VA QX56_RS13700 ENOG41087NI Sulfite exporter TauE/SafE QX56_RS13705 ENOG4105VFE sira family QX56_RS13710 ENOG4107TPS domain protein QX56_RS13720 ENOG4105VFE sira family QX56_RS13725 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase QX56_RS13730 ENOG4105XTG Pfam:DUF156 QX56_RS13735 ENOG4108VK3 Cupin 2 Conserved Barrel Domain Protein QX56_RS13745 ENOG41090E6 transcriptional regulator MERR family QX56_RS13760 ENOG4105C37 (CBS) domain QX56_RS13770 ENOG410825D TRANSCRIPTIONal REGULATOR, LysR family QX56_RS13775 ENOG4105H3G oxidoreductase QX56_RS13780 ENOG4105PGM cation diffusion facilitator family transporter QX56_RS13785 ENOG41090U3 tautomerase QX56_RS13805 ENOG4105KMT branched-chain amino acid QX56_RS13810 ENOG4108UMN azlc family QX56_RS13815 ENOG4108ZRZ Transcriptional regulator (AsnC family) QX56_RS13820 ENOG41067XF inhibitor QX56_RS13835 ENOG41064BW Protein of unknown function (DUF2568) QX56_RS13845 ENOG41075D4 Aminoglycoside 6-adenylyltransferase QX56_RS13850 ENOG4105EA8 2-Nitropropane dioxygenase QX56_RS13855 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) QX56_RS13865 ENOG4108MEK Metal-binding protein YodA QX56_RS13870 ENOG410904A RNA polymerase QX56_RS13875 ENOG4105CPC Aldo Keto reductase QX56_RS13885 ENOG4108KAM Transcriptional regulator QX56_RS13890 ENOG4105C7F AcnD-accessory protein PrpF QX56_RS13895 ENOG41083Q9 chitosanase QX56_RS13900 ENOG4105X5K response regulator receiver protein QX56_RS13905 ENOG4108VQT Alpha beta hydrolase fold protein QX56_RS13910 ENOG4106H77 Inherit from COG: SH3 type 3 domain-containing protein QX56_RS13915 ENOG4106H77 Inherit from COG: SH3 type 3 domain-containing protein QX56_RS13920 ENOG4105Z0X Glyoxalase Bleomycin resistance protein (Dioxygenase QX56_RS13930 ENOG4105PGS Spore coat protein QX56_RS13935 ENOG4105E2A Dehydrogenase QX56_RS13950 ENOG4105VUF Transcriptional regulator QX56_RS13960 ENOG4105DQ4 alcohol dehydrogenase QX56_RS13965 ENOG4108Z0Z intracellular protease Pfpi family QX56_RS13970 ENOG4108HKT sucrose-6-phosphate hydrolase QX56_RS13975 ENOG4105F3R pts system mannose fructose sorbose family iid QX56_RS13980 ENOG4105ETZ PTS System QX56_RS13985 ENOG4108IQ3 PTS system QX56_RS13990 ENOG4105YHU PTS system QX56_RS13995 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family QX56_RS14000 ENOG4105C85 amino acid QX56_RS14005 ENOG4105N14 lysine exporter protein LysE YggA QX56_RS14010 ENOG4108NGU Transcriptional regulator QX56_RS14015 ENOG4105JVQ RNA Polymerase QX56_RS14020 ENOG4108P49 AntiSigma factor QX56_RS14025 ENOG4105EXC Acyl-transferase QX56_RS14030 ENOG4105WDR QX56_RS14035 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) QX56_RS14040 ENOG41082JN Transcriptional regulator QX56_RS14050 ENOG4105TMB Formate nitrite transporter QX56_RS14055 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) QX56_RS14060 ENOG4108JB9 formate dehydrogenase QX56_RS14075 ENOG4105C28 cystathionine QX56_RS14090 ENOG4108WVK Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity) QX56_RS14105 ENOG4107XRG penicillin-binding protein QX56_RS14110 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) QX56_RS14115 ENOG4105DBI uridine monophosphokinase QX56_RS14120 ENOG4105CFP Peptidase U32 QX56_RS14125 ENOG4105XYU peptidase (U32 family) QX56_RS14135 ENOG4105HHA aminodeoxychorismate lyase QX56_RS14140 ENOG4105VPH UPF0473 protein QX56_RS14145 ENOG4108Z08 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) QX56_RS14150 ENOG4105VBH UPF0297 protein QX56_RS14155 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) QX56_RS14160 ENOG4105C02 permease QX56_RS14165 ENOG4105CDA abc transporter atp-binding protein QX56_RS14170 ENOG4105CT1 (ABC) transporter QX56_RS14175 ENOG4105EAD ABC transporter QX56_RS14180 ENOG4105DRP amino acid AbC transporter QX56_RS14185 ENOG41060CR QX56_RS14195 ENOG4105C7H Helicase, RecD TraA family QX56_RS14205 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) QX56_RS14210 ENOG4105C3J Cysteine desulfurase QX56_RS14220 ENOG4105D1H recombination factor protein RarA QX56_RS14225 ENOG4105CUZ uba thif-type nad fad binding protein QX56_RS14230 ENOG4105C9M aspartyl-trna synthetase QX56_RS14235 ENOG4105CUT histidyl-tRNA synthetase QX56_RS14240 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase QX56_RS14250 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) QX56_RS14255 ENOG4109003 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity) QX56_RS14260 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) QX56_RS14265 ENOG41067VP Protein of unknown function (DUF1049) QX56_RS14270 ENOG4105NCW Trka-c domain protein QX56_RS14275 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) QX56_RS14285 ENOG4105CKP Polysaccharide Biosynthesis Protein QX56_RS14290 ENOG4108QG2 Membrane QX56_RS14295 ENOG4105NAP QX56_RS14300 ENOG4105VIE preprotein translocase, subunit YajC QX56_RS14305 ENOG4105C6U Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity) QX56_RS14310 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) QX56_RS14315 ENOG41061AI Protein of unknown function (DUF2905) QX56_RS14320 ENOG4105CKJ The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity) QX56_RS14325 ENOG4105KA4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity) QX56_RS14335 ENOG4105IE8 Alpha-ketoglutarate permease QX56_RS14340 ENOG4105CK5 oxidoreductase QX56_RS14360 ENOG4105BZG amino acid carrier protein QX56_RS14365 ENOG4105CDY transcriptional regulatory protein QX56_RS14375 ENOG4106678 morphogenetic protein associated with SpoVID QX56_RS14380 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) QX56_RS14385 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase QX56_RS14390 ENOG4108IYU L-aspartate oxidase QX56_RS14405 ENOG4105CQC Prephenate dehydratase QX56_RS14410 ENOG41090I5 UPF0735 ACT domain-containing protein QX56_RS14415 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control QX56_RS14425 ENOG4105K46 50S ribosomal protein l27 QX56_RS14430 ENOG4105X36 (ribosomal) protein QX56_RS14435 ENOG4105KK9 This protein binds to 23S rRNA in the presence of protein L20 (By similarity) QX56_RS14450 ENOG4107QMS site-determining protein QX56_RS14455 ENOG4107YDG Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity) QX56_RS14460 ENOG4105YHC Rod shape-determining protein MreD QX56_RS14470 ENOG4105DFF Rod shape-determining protein mreb QX56_RS14475 ENOG4105W5Q DNA repair protein (RadC QX56_RS14480 ENOG4108Z03 MAF-like protein QX56_RS14490 ENOG4106A3R peptidase QX56_RS14495 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase QX56_RS14500 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) QX56_RS14510 ENOG4106AR7 Spore coat protein QX56_RS14515 ENOG41068KH stage VI sporulation protein D QX56_RS14520 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase QX56_RS14525 ENOG4105D52 delta-aminolevulinic acid dehydratase QX56_RS14535 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) QX56_RS14545 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) QX56_RS14555 ENOG4105WHM Necessary for normal cell division and for the maintenance of normal septation (By similarity) QX56_RS14560 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) QX56_RS14565 ENOG4108IUQ atp-dependent protease QX56_RS14570 ENOG4105CHN ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity) QX56_RS14575 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation QX56_RS14585 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) QX56_RS14590 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) QX56_RS14595 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) QX56_RS14600 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) QX56_RS14605 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase QX56_RS14610 ENOG4108ZP8 Acetolactate synthase small subunit QX56_RS14615 ENOG4105C7K acetolactate synthase QX56_RS14625 ENOG4105I4A GCN5-related N-acetyltransferase QX56_RS14630 ENOG4107KM7 Heat induced stress protein YflT QX56_RS14640 ENOG4105M59 Phosphodiesterase, mj0936 family QX56_RS14645 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) QX56_RS14650 ENOG4105ED0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity) QX56_RS14655 ENOG4108XJQ germination protein QX56_RS14660 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) QX56_RS14665 ENOG41067TZ transcriptional regulator, MarR family QX56_RS14670 ENOG4105PFC Transcriptional regulator QX56_RS14680 ENOG4105E33 succinate dehydrogenase QX56_RS14690 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit QX56_RS14700 ENOG4105CFH Aspartokinase QX56_RS14705 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) QX56_RS14710 ENOG4105K63 Thioredoxin QX56_RS14715 ENOG4105CZZ Alpha-N-arabinofuranosidase (EC 3.2.1.55) QX56_RS14720 ENOG4105C10 Electron transfer flavoprotein QX56_RS14725 ENOG4105BZJ Electron transfer flavoprotein QX56_RS14730 ENOG41060WC Enoyl-CoA hydratase QX56_RS14735 ENOG4107Z3H Transcriptional regulator, TetR family QX56_RS14740 ENOG4105CEY Amp-dependent synthetase and ligase QX56_RS14750 ENOG4105C98 muts2 protein QX56_RS14755 ENOG4105DCG PHP domain protein QX56_RS14770 ENOG4107FSS Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) QX56_RS14775 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) QX56_RS14780 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) QX56_RS14790 ENOG4108RWN rrna methyltransferase QX56_RS14795 ENOG41067MF small acid-soluble spore protein QX56_RS14805 ENOG4105CQB FAD linked oxidase domain protein QX56_RS14810 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) QX56_RS14825 ENOG4105CZZ Alpha-N-arabinofuranosidase (EC 3.2.1.55) QX56_RS14830 ENOG4105DRS transport system, permease QX56_RS14845 ENOG4108MDK Dehydrogenase QX56_RS14855 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase QX56_RS14860 ENOG4105EF1 ribulokinase QX56_RS14870 ENOG4107PMW Arabinan endo-1,5-alpha-L-arabinosidase QX56_RS14875 ENOG4105CN9 Peptidase m42 family protein QX56_RS14885 ENOG410696E Membrane QX56_RS14890 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) QX56_RS14895 ENOG4105VJV 50s ribosomal protein L35 QX56_RS14900 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) QX56_RS14910 ENOG41067MG lrgb family QX56_RS14920 ENOG4105DY9 regulatoR QX56_RS14925 ENOG4108HRK Histidine kinase QX56_RS14935 ENOG4105C22 threonyL-tRNA synthetase QX56_RS14940 ENOG4108TDW sporulation protein YtxC QX56_RS14960 ENOG4108Z11 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity) QX56_RS14965 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) QX56_RS14970 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase QX56_RS14975 ENOG4105KVH Transcriptional regulator QX56_RS14980 ENOG4105F27 Major Facilitator QX56_RS14985 ENOG4105CV8 reductase QX56_RS14990 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) QX56_RS15000 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) QX56_RS15005 ENOG4105C2M dna polymerase I QX56_RS15010 ENOG4105BZU Histidine kinase QX56_RS15015 ENOG4105DPZ Two component transcriptional regulator (Winged helix family QX56_RS15020 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) QX56_RS15025 ENOG4108HMX isocitrate dehydrogenase (NADP) QX56_RS15030 ENOG4105BZN citrate synthase QX56_RS15040 ENOG4108REF Sporulation integral membrane protein ytvi QX56_RS15045 ENOG4105FS0 cytoplasmic membrane protein QX56_RS15050 ENOG4105CA9 Pyruvate kinase QX56_RS15055 ENOG4105CTQ phosphohexokinase QX56_RS15065 ENOG4108IEY Carboxyl transferase domain QX56_RS15070 ENOG4105C6K Malic enzyme QX56_RS15075 ENOG4105C0B DNA polymerase III (alpha subunit) QX56_RS15080 ENOG4105VV2 QX56_RS15090 ENOG4106EVM QX56_RS15095 ENOG4105SFS phosphoesterase RecJ domain protein QX56_RS15110 ENOG410635A Membrane QX56_RS15115 ENOG4105CH2 amidohydrolase QX56_RS15135 ENOG4105DEN Luciferase family QX56_RS15140 ENOG4105CDA abc transporter atp-binding protein QX56_RS15165 ENOG4108XSB acetyltransferase, (GNAT) family QX56_RS15170 ENOG4108KSA LysR family transcriptional regulator QX56_RS15175 ENOG4105E8R UPF0173 metal-dependent hydrolase QX56_RS15185 ENOG4105CH7 arginosuccinase QX56_RS15190 ENOG4105CDH Citrulline--aspartate ligase QX56_RS15195 ENOG4105EPU Molybdenum cofactor synthesis domain protein QX56_RS15200 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) QX56_RS15210 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) QX56_RS15215 ENOG4105KBJ sporulation protein ytfj QX56_RS15225 ENOG4105VK3 rdd domain containing protein QX56_RS15230 ENOG4105D07 Signal peptide peptidase, SppA QX56_RS15235 ENOG4108KKH Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) QX56_RS15240 ENOG4105EFZ amidohydrolase QX56_RS15245 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) QX56_RS15280 ENOG4105U5Y Transcriptional regulator QX56_RS15290 ENOG4105BZU Histidine kinase QX56_RS15295 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) QX56_RS15300 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) QX56_RS15310 ENOG4105F1V Acetoin utilization protein QX56_RS15315 ENOG4105W87 Cbs domain QX56_RS15320 ENOG4105DGU Histone deacetylase QX56_RS15325 ENOG4105ER2 Ompa motb domain protein QX56_RS15330 ENOG4107R0U MotA TolQ exbB proton channel QX56_RS15335 ENOG4105ETE Transcriptional regulator (LacI family QX56_RS15340 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase QX56_RS15360 ENOG4105DFU Cell wall formation (By similarity) QX56_RS15370 ENOG4108VDD TRNA binding domain protein QX56_RS15385 ENOG4108V0E nucleoside 2-deoxyribosyltransferase YtoQ QX56_RS15400 ENOG4105C6K Malic enzyme QX56_RS15405 ENOG4105C8F Beta-lactamase domain protein QX56_RS15410 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) QX56_RS15420 ENOG4108V15 phosphotransferase enzyme family QX56_RS15425 ENOG4108IUM Glycogen debranching enzyme QX56_RS15440 ENOG4107F58 2'-5' rna ligase QX56_RS15445 ENOG4105C6T cysteine synthase QX56_RS15450 ENOG4107QSE Dipeptidase QX56_RS15455 ENOG4105C7N Xanthine uracil vitamin C permease QX56_RS15470 ENOG4105YW5 deoR family transcriptional regulator QX56_RS15485 ENOG4105CBX hi0933 family QX56_RS15490 ENOG4105C94 Transporter QX56_RS15500 ENOG4105MU9 integral membrane protein QX56_RS15505 ENOG4105DDC Oxidoreductase domain protein QX56_RS15515 ENOG4105F5H Glycosyl Hydrolase Family 88 QX56_RS15525 ENOG41075H3 AraC family transcriptional regulator QX56_RS15535 ENOG4105C50 Binding-protein-dependent transport systems, inner membrane component QX56_RS15545 ENOG4106A3M Cytochrome p-450 QX56_RS15550 ENOG4105CZF Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) QX56_RS15555 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) QX56_RS15560 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) QX56_RS15565 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) QX56_RS15570 ENOG4108W8G Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP (By similarity) QX56_RS15575 ENOG4105NTD Inherit from COG: Hydrolase QX56_RS15605 ENOG41085GJ domain protein QX56_RS15610 ENOG4105C8T Leucyl-tRNA synthetase QX56_RS15620 ENOG4105BZU Histidine kinase QX56_RS15625 ENOG410605W Major Facilitator QX56_RS15630 ENOG4106UBQ QX56_RS15640 ENOG4105C19 ABC transporter QX56_RS15645 ENOG4105EWM Histidine kinase QX56_RS15655 ENOG4107R34 abc transporter permease protein QX56_RS15660 ENOG4105C19 ABC transporter QX56_RS15675 ENOG4105DVE abc transporter atp-binding protein QX56_RS15680 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family QX56_RS15690 ENOG4105N5T Radical SAM Protein QX56_RS15705 ENOG4105E8V Alpha Beta Hydrolase Fold protein QX56_RS15710 ENOG4108Z0R Transferase QX56_RS15715 ENOG4105C85 amino acid QX56_RS15720 ENOG4105CAQ asparagine synthetase QX56_RS15725 ENOG4105CPH Catalyzes the formation of S-adenosylmethionine from methionine and ATP QX56_RS15730 ENOG4105DJ1 Phosphoenolpyruvate Carboxylase QX56_RS15745 ENOG4105D2X ABC transporter substrate-binding protein QX56_RS15755 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component QX56_RS15770 ENOG4108RMU ferritin dps family protein QX56_RS15785 ENOG4106762 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity) QX56_RS15790 ENOG4105VAS Could be involved in insertion of integral membrane proteins into the membrane (By similarity) QX56_RS15795 ENOG4108V2W Carbonate dehydratase QX56_RS15815 ENOG4105CC5 ABC transporter QX56_RS15820 ENOG4105CC5 ABC transporter QX56_RS15825 ENOG4105DIK (ABC) transporter QX56_RS15830 ENOG4105DSE periplasmic solute binding protein QX56_RS15835 ENOG4105DTQ mandelate racemase muconate lactonizing QX56_RS15840 ENOG4105CEY Amp-dependent synthetase and ligase QX56_RS15845 ENOG4108IPT Naphthoate synthase QX56_RS15850 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) QX56_RS15855 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) QX56_RS15860 ENOG4105E4F Isochorismate synthase QX56_RS15880 ENOG4108IAJ Nad-dependent epimerase dehydratase QX56_RS15885 ENOG4107SBE Glycosyl transferase (Group 1 QX56_RS15900 ENOG4107SBE Glycosyl transferase (Group 1 QX56_RS15905 ENOG4108KS4 Spore coat protein QX56_RS15920 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) QX56_RS15930 ENOG4105CNB Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) QX56_RS16060 ENOG4105N67 Proton-coupled thiamine transporter YuaJ QX56_RS16065 ENOG4105VRR gCN5-related N-acetyltransferase QX56_RS16070 ENOG4105DZ6 Band 7 protein QX56_RS16080 ENOG4106DF1 QX56_RS16085 ENOG4108VNY MOSC domain protein QX56_RS16090 ENOG4108JB8 alcohol dehydrogenase QX56_RS16100 ENOG4105TRT Transcriptional regulator QX56_RS16115 ENOG4105CZN Potassium uptake protein QX56_RS16120 ENOG4107I77 yiaA/B two helix domain QX56_RS16125 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj QX56_RS16145 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) QX56_RS16155 ENOG4105EE0 oxidoreductase QX56_RS16160 ENOG4105DKG l-rhamnose isomerase QX56_RS16165 ENOG4105M10 Involved in the anomeric conversion of L-rhamnose (By similarity) QX56_RS16170 ENOG4105DET Rhamnulokinase QX56_RS16175 ENOG4105E98 transcriptional regulator DeoR family QX56_RS16185 ENOG4105C8Q Methyl-accepting chemotaxis QX56_RS16190 ENOG4105C8Q Methyl-accepting chemotaxis QX56_RS16195 ENOG4105C8Q Methyl-accepting chemotaxis QX56_RS16200 ENOG4105C8Q Methyl-accepting chemotaxis QX56_RS16215 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme QX56_RS16225 ENOG4105C37 (CBS) domain QX56_RS16240 ENOG4107PBV potassium channel QX56_RS16245 ENOG4107PBV potassium channel QX56_RS16260 ENOG4107QYV phosphohexose isomerase QX56_RS16270 ENOG4107QW4 alcohol dehydrogenase QX56_RS16275 ENOG4105WG9 Conserved Protein QX56_RS16285 ENOG4105CHM Aminotransferase QX56_RS16290 ENOG4108ZB6 transcriptional regulator AsnC family QX56_RS16295 ENOG4108MUZ hydrolase QX56_RS16305 ENOG4105C87 Aminotransferase class I and II QX56_RS16310 ENOG4108HGU Histidine kinase QX56_RS16315 ENOG4105Y38 Kinase-associated protein B QX56_RS16335 ENOG4105BZ4 penicillin-binding protein QX56_RS16340 ENOG4105KIR Thiol-disulfide oxidoreductase dcc QX56_RS16355 ENOG4108MRH transcriptional regulatory protein QX56_RS16360 ENOG4105DIH basic membrane QX56_RS16365 ENOG4108JQ9 ABC transporter QX56_RS16370 ENOG4105UIB (ABC) transporter QX56_RS16390 ENOG4105D65 subunit l QX56_RS16395 ENOG4105HC0 Na H antiporter QX56_RS16400 ENOG4108ZE9 Monovalent cation H antiporter subunit C QX56_RS16405 ENOG4108JPZ Monovalent cation H antiporter subunit D QX56_RS16410 ENOG4105SC1 monovalent cation H antiporter subunit E QX56_RS16420 ENOG4105KJM monovalent cation h antiporter subunit g QX56_RS16425 ENOG4105KA0 thioesterase Superfamily protein QX56_RS16435 ENOG4105BZU Histidine kinase QX56_RS16460 ENOG4105D58 Diguanylate phosphodiesterase QX56_RS16465 ENOG4105DAP Nicotinate phosphoribosyltransferase QX56_RS16490 ENOG4105C02 permease QX56_RS16510 ENOG410904N short-chain dehydrogenase reductase QX56_RS16545 ENOG4108K8K Transcriptional regulator QX56_RS16550 ENOG4105DCF alanine dehydrogenase QX56_RS16560 ENOG4105WQT MbtH domain protein QX56_RS16565 ENOG4105CEY Amp-dependent synthetase and ligase QX56_RS16570 ENOG4105WQI isochorismatase QX56_RS16575 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase QX56_RS16580 ENOG4105E4F Isochorismate synthase QX56_RS16585 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase QX56_RS16590 ENOG4105NIV Esterase QX56_RS16610 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) QX56_RS16620 ENOG41069ER domain protein QX56_RS16630 ENOG4105CEP NADH dehydrogenase QX56_RS16635 ENOG4105CAY ferredoxin--nadp reductase QX56_RS16650 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 QX56_RS16655 ENOG4108YX9 iron--sulfur cluster insertion protein erpA QX56_RS16670 ENOG4105ZKE UPF0349 protein QX56_RS16685 ENOG41083MR nifu domain-containing protein QX56_RS16690 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein QX56_RS16695 ENOG4105D5I Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity) QX56_RS16700 ENOG4108IYI Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity) QX56_RS16705 ENOG4105D6E homoserine dehydrogenase QX56_RS16715 ENOG4108W5N phosphatidylglycerophosphatase a QX56_RS16720 ENOG4105D4U had-superfamily hydrolase, subfamily iia QX56_RS16730 ENOG4105MMD transcriptional regulator QX56_RS16735 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) QX56_RS16740 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) QX56_RS16745 ENOG4105FAA peptidase M23 QX56_RS16750 ENOG4108YTE sporulation protein YunB QX56_RS16755 ENOG4105KZD Domain of unknown function (DUF1805) QX56_RS16760 ENOG4107R8B 5'-nucleotidase QX56_RS16770 ENOG4105I3N Conserved Protein QX56_RS16780 ENOG4105CD3 dihydroorotase QX56_RS16785 ENOG4105G9B Transcriptional regulator QX56_RS16800 ENOG4105FFA Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin (By similarity) QX56_RS16805 ENOG4105VT2 5-hydroxyisourate hydrolase QX56_RS16815 ENOG4107YV9 domain protein QX56_RS16820 ENOG4105CE2 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding QX56_RS16835 ENOG4105XRQ Xanthine dehydrogenase accessory factor QX56_RS16840 ENOG4105C5R Aminotransferase QX56_RS16850 ENOG4108K8S endonuclease I QX56_RS16855 ENOG4108IJ9 (ABC) transporter QX56_RS16860 ENOG4105FDP GntR family transcriptional regulator QX56_RS16865 ENOG4108KPW sugar kinase QX56_RS16870 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component QX56_RS16875 ENOG4105F0P binding-protein-dependent transport systems inner membrane Component QX56_RS16880 ENOG4105XN3 extracellular solute-binding protein family 1 QX56_RS16885 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine QX56_RS16890 ENOG4105PKS Excinuclease abc c subunit domain protein QX56_RS16895 ENOG4107VFR oxidoreductase QX56_RS16910 ENOG41090KQ Glyoxalase Bleomycin resistance protein (Dioxygenase QX56_RS16915 ENOG4105NPE arsR family transcriptional regulator QX56_RS16920 ENOG4105DIW FeS assembly protein SUFB QX56_RS16925 ENOG4108UNV SUF system FeS assembly protein, NifU family QX56_RS16930 ENOG4105C9B Cysteine desulfurase QX56_RS16935 ENOG4105JRK feS assembly protein SufD QX56_RS16940 ENOG4105C3K feS assembly ATPase SufC QX56_RS16950 ENOG4105D01 (LipO)protein QX56_RS16955 ENOG4108UMI ABC transporter, permease QX56_RS16960 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) QX56_RS16985 ENOG4105KE9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity) QX56_RS16990 ENOG41080E8 Transcriptional regulator, Spx MgsR family QX56_RS16995 ENOG4105C1G acyl-Coa dehydrogenase QX56_RS17000 ENOG4105CHU acetyl-coa acetyltransferase QX56_RS17025 ENOG41067TZ transcriptional regulator, MarR family QX56_RS17030 ENOG4105C0R drug resistance transporter emrb qaca subfamily QX56_RS17035 ENOG4105MDS 4-oxalocrotonate tautomerase QX56_RS17050 ENOG4105EGI Transcriptional regulator QX56_RS17060 ENOG4105E0A ABC, transporter QX56_RS17080 ENOG4105E1F short-chain dehydrogenase reductase QX56_RS17085 ENOG4105HUF DNA protection during starvation protein QX56_RS17090 ENOG4105C0H protease QX56_RS17100 ENOG4105F3H Histidine kinase QX56_RS17105 ENOG41067SE Tetr family transcriptional regulator QX56_RS17110 ENOG4105C9Q fumarate hydratase class II QX56_RS17135 ENOG4105WH1 Two component transcriptional regulator luxr family QX56_RS17140 ENOG4105ENE Histidine kinase QX56_RS17155 ENOG41087YS Phage shock protein A QX56_RS17170 ENOG4108WBT adenosyltransferase QX56_RS17175 ENOG4105E0A ABC, transporter QX56_RS17180 ENOG4105EHG Permease protein QX56_RS17185 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) QX56_RS17190 ENOG4105EWI Short-chain dehydrogenase reductase Sdr QX56_RS17195 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein QX56_RS17205 ENOG4105DPZ Two component transcriptional regulator (Winged helix family QX56_RS17215 ENOG4106DF4 Sigma-70, region 4 QX56_RS17220 ENOG4105F0F Oxalate decarboxylase QX56_RS17230 ENOG4107RBB ABC transporter, permease QX56_RS17235 ENOG4105C19 ABC transporter QX56_RS17240 ENOG4108WMK Efflux transporter RND family MFP subunit QX56_RS17245 ENOG4105E0A ABC, transporter QX56_RS17250 ENOG4105EHG Permease protein QX56_RS17255 ENOG4105DQ5 transport system permease protein QX56_RS17270 ENOG4105D5Q Arginine ornithine antiporter QX56_RS17280 ENOG4107K5X Membrane-bound metal-dependent hydrolase QX56_RS17285 ENOG4107QZ2 Sulfatase QX56_RS17290 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family QX56_RS17295 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein QX56_RS17300 ENOG4105E0C molybdate abc transporter QX56_RS17315 ENOG4105EEQ Na H antiporter QX56_RS17320 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) QX56_RS17325 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) QX56_RS17330 ENOG4105EEM helicase QX56_RS17335 ENOG4105EN6 Membrane QX56_RS17345 ENOG4107ZQN disulfide bond QX56_RS17350 ENOG4105C59 p-type ATPase QX56_RS17355 ENOG4105C59 p-type ATPase QX56_RS17360 ENOG410681U heavy metal transport detoxification protein QX56_RS17365 ENOG4105VPX protein, conserved in bacteria QX56_RS17370 ENOG4105D9R oxidoreductase QX56_RS17375 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) QX56_RS17380 ENOG4105ME7 Membrane QX56_RS17385 ENOG4105RXJ QX56_RS17390 ENOG4105KPY Small multidrug resistance protein QX56_RS17395 ENOG4105KBX Transcriptional regulator, TetR family QX56_RS17400 ENOG4105EWI Short-chain dehydrogenase reductase Sdr QX56_RS17405 ENOG4108UH4 Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity) QX56_RS17410 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) QX56_RS17420 ENOG4105XZU Preprotein translocase, subunit SecG QX56_RS17445 ENOG4105KVH Transcriptional regulator QX56_RS17450 ENOG4105C8Q Methyl-accepting chemotaxis QX56_RS17455 ENOG4105R40 Glycine betaine carnitine choline QX56_RS17460 ENOG4108HQR Glycine betaine QX56_RS17465 ENOG4105E90 ABC transporter QX56_RS17470 ENOG4108IJ8 ABC transporter QX56_RS17475 ENOG4107HG4 Transcriptional regulator QX56_RS17485 ENOG4105H5S QX56_RS17500 ENOG41082BM Transcriptional regulator, arsr family QX56_RS17505 ENOG4105R40 Glycine betaine carnitine choline QX56_RS17510 ENOG4108HQR Glycine betaine QX56_RS17515 ENOG4105E90 ABC transporter QX56_RS17520 ENOG4108IJ8 ABC transporter QX56_RS17525 ENOG4107HG4 Transcriptional regulator QX56_RS17530 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein QX56_RS17535 ENOG4108QCI YvbH-like oligomerisation region QX56_RS17545 ENOG4105T65 Membrane-associated protein QX56_RS17550 ENOG4108W0I acetyltransferase QX56_RS17555 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) QX56_RS17560 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) QX56_RS17565 ENOG4105CP7 Triose-phosphate isomerase QX56_RS17570 ENOG4105BZA Phosphoglycerate kinase QX56_RS17575 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase QX56_RS17590 ENOG4105CMD Transcriptional regulator, GntR family QX56_RS17595 ENOG4105DEN Luciferase family QX56_RS17600 ENOG4105GZI Transcriptional regulator QX56_RS17605 ENOG4107RT3 EamA-like transporter family QX56_RS17615 ENOG4105VRS hydrolase family 18 QX56_RS17620 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) QX56_RS17625 ENOG4107QR9 Iron-sulfur cluster binding protein QX56_RS17630 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) QX56_RS17640 ENOG4105BZU Histidine kinase QX56_RS17645 ENOG4105KCT ABC transporter QX56_RS17650 ENOG4108M15 ABC transporter QX56_RS17655 ENOG4107R6F Alpha Beta Hydrolase Fold protein QX56_RS17660 ENOG4108MJI response regulator QX56_RS17675 ENOG4105EG2 ABC transporter, permease QX56_RS17685 ENOG4107FKK extracellular solute-binding protein family 1 QX56_RS17695 ENOG4105JXH GntR family transcriptional regulator QX56_RS17700 ENOG4105DAA L-lactate QX56_RS17705 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) QX56_RS17715 ENOG4108ZPC Polysaccharide pyruvyl transferase QX56_RS17720 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase QX56_RS17725 ENOG4105MME Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family QX56_RS17730 ENOG4105D3Q Sugar transferase QX56_RS17740 ENOG4105K64 Glycosyl transferase, family 2 QX56_RS17750 ENOG4107QRS glycosyltransferase group 2 family protein QX56_RS17755 ENOG41068W6 Capsular polysaccharide biosynthesis protein QX56_RS17760 ENOG4108KMV Glycosyl transferase (Group 1 QX56_RS17765 ENOG4105K64 Glycosyl transferase, family 2 QX56_RS17770 ENOG4108PQP glycosyl transferase group 1 QX56_RS17780 ENOG4108QV3 biosynthesis protein QX56_RS17785 ENOG4105HTX biosynthesis protein QX56_RS17795 ENOG4105EBR Carboxylesterase QX56_RS17805 ENOG4105PY6 Phenolic acid decarboxylase QX56_RS17810 ENOG4105NI3 Protein of unknown function (DUF3237) QX56_RS17820 ENOG4105FQP Beta-lactamase QX56_RS17825 ENOG4105EDQ levansucrase EC 2.4.1.10 QX56_RS17830 ENOG4108HKT sucrose-6-phosphate hydrolase QX56_RS17835 ENOG4107QTZ amino acid QX56_RS17860 ENOG4105DNP FAD linked oxidase domain protein QX56_RS17865 ENOG4105IRW patatin-like phospholipase family protein QX56_RS17875 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) QX56_RS17880 ENOG4107URF beta-phospho-glucomutase QX56_RS17885 ENOG4105CG3 alpha amylase, catalytic region QX56_RS17900 ENOG4105EG2 ABC transporter, permease QX56_RS17905 ENOG4105D56 permease protein QX56_RS17910 ENOG4107FKK extracellular solute-binding protein family 1 QX56_RS17915 ENOG4108IUK alpha amylase, catalytic QX56_RS17920 ENOG4105FKQ transcriptional regulator QX56_RS17925 ENOG4108URH decarboxylase QX56_RS17930 ENOG4105TPC MazG nucleotide pyrophosphohydrolase domain QX56_RS17935 ENOG4105CHH sulfate transporter QX56_RS17940 ENOG4108V2W Carbonate dehydratase QX56_RS17945 ENOG4105C5I Dehydrogenase QX56_RS17955 ENOG4105C19 ABC transporter QX56_RS17960 ENOG4105EWM Histidine kinase QX56_RS17970 ENOG4107A6P QX56_RS17975 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase QX56_RS17980 ENOG4105KRI phosphocarrier protein (HPr QX56_RS17985 ENOG4105CIE May be required for sporulation (By similarity) QX56_RS17990 ENOG4105CHW UPF0052 protein QX56_RS17995 ENOG4105C21 Displays ATPase and GTPase activities (By similarity) QX56_RS18000 ENOG4108Z4K mutator MutT protein QX56_RS18005 ENOG4105C3M thioredoxin reductase QX56_RS18020 ENOG4105BZ1 (ABC) transporter QX56_RS18030 ENOG4106FGC QX56_RS18040 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase QX56_RS18045 ENOG4105C0S IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) QX56_RS18050 ENOG4105CJV Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase QX56_RS18055 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) QX56_RS18060 ENOG4105ECC imidazole-glycerol-phosphate dehydratase QX56_RS18065 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) QX56_RS18070 ENOG4107RN8 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) QX56_RS18075 ENOG4105C49 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity) QX56_RS18085 ENOG4108E16 pectate lyase QX56_RS18090 ENOG4108S4C acetyltransferase QX56_RS18095 ENOG4107XGZ Hydrolase QX56_RS18100 ENOG4105HKU nucleoside recognition domain-containing protein QX56_RS18105 ENOG4105C3B Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity) QX56_RS18110 ENOG4105D1C Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity) QX56_RS18115 ENOG4105CE4 GlcNAc 6-P deacetylase QX56_RS18120 ENOG4105CKA Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity) QX56_RS18130 ENOG41088CQ domain protein QX56_RS18140 ENOG4106A3M Cytochrome p-450 QX56_RS18145 ENOG410625E QX56_RS18160 ENOG41086DT Membrane protein of unknown function QX56_RS18165 ENOG41067S9 phage shock protein C, PspC QX56_RS18170 ENOG4108PY7 QX56_RS18190 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) QX56_RS18195 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) QX56_RS18210 ENOG4105MKU Transcriptional regulator QX56_RS18230 ENOG4105CN1 protease QX56_RS18235 ENOG4105CRP Part of the ABC transporter FtsEX involved in QX56_RS18240 ENOG4105CAK Cell division ATP-binding protein ftsE QX56_RS18265 ENOG4105MS2 ribosomal subunit Interface protein QX56_RS18280 ENOG4105MQ3 flagellar protein FliS QX56_RS18285 ENOG4107RT6 flagellar hook-associated QX56_RS18290 ENOG41083S7 flagellar protein FlaG QX56_RS18295 ENOG4105I03 Flagellin QX56_RS18300 ENOG41085Y9 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) QX56_RS18305 ENOG4105W5T Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity) QX56_RS18310 ENOG4105MKD QX56_RS18315 ENOG4105DTJ flagellar hook-associated protein QX56_RS18320 ENOG4105E1Q flagellar hook-associated protein QX56_RS18335 ENOG4105RU3 QX56_RS18340 ENOG41081UC Inherit from COG: Competence protein QX56_RS18360 ENOG4105WH1 Two component transcriptional regulator luxr family QX56_RS18365 ENOG4105BZU Histidine kinase QX56_RS18370 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein QX56_RS18375 ENOG4108KGH TRANSCRIPTIONal QX56_RS18380 ENOG4105ESV Glycosyl transferase, family 4 QX56_RS18385 ENOG4107EF8 Glycosyl transferase (Group 1 QX56_RS18400 ENOG4105QZI O-Antigen Polymerase QX56_RS18405 ENOG4105C6Y Udp-glucose 6-dehydrogenase QX56_RS18410 ENOG4107RA4 Glycosyl transferase (Group 1 QX56_RS18415 ENOG4105PSV Polysaccharide Biosynthesis Protein QX56_RS18425 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase QX56_RS18430 ENOG4105JFG SpoIID LytB domain protein QX56_RS18445 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase QX56_RS18450 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase QX56_RS18455 ENOG4107VDP teichoic acid biosynthesis QX56_RS18460 ENOG41088M2 Glycosyl transferase family 2 QX56_RS18465 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase QX56_RS18470 ENOG4105EY8 ABC transporter QX56_RS18480 ENOG4107SJB teichoic acid biosynthesis QX56_RS18485 ENOG4108NMT An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon (By similarity) QX56_RS18490 ENOG4107ZIC Glycerol-3-phosphate cytidylyltransferase QX56_RS18500 ENOG4107RZX Teichoic acid biosynthesis protein QX56_RS18505 ENOG410651K Teichoic acid biosynthesis protein C QX56_RS18515 ENOG4105DG6 mannose-6-phosphate isomerase QX56_RS18530 ENOG4108NHD germination protein QX56_RS18535 ENOG4105C54 Major Facilitator superfamily QX56_RS18540 ENOG4108KGH TRANSCRIPTIONal QX56_RS18545 ENOG4105J7I hydrolase QX56_RS18550 ENOG4105K4H Nlp p60 protein QX56_RS18555 ENOG4105PNM synthesis protein QX56_RS18565 ENOG4105N98 Capsule biosynthesis protein capB QX56_RS18570 ENOG4105ETE Transcriptional regulator (LacI family QX56_RS18575 ENOG4108RVA ribokinase QX56_RS18580 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) QX56_RS18585 ENOG4105C2J ABC transporter QX56_RS18590 ENOG4105CNN ABC, transporter QX56_RS18595 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator QX56_RS18610 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein QX56_RS18615 ENOG4107FQX Alpha-acetolactate decarboxylase QX56_RS18625 ENOG4107RSM transcriptional regulator QX56_RS18640 ENOG4106UIA QX56_RS18655 ENOG4107XC4 flavin reductase domain protein, FMN-binding QX56_RS18665 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) QX56_RS18675 ENOG4105CAH Chromate QX56_RS18680 ENOG4105FGV Chromate QX56_RS18690 ENOG4108WS4 fmn reductase QX56_RS18695 ENOG4107V2S Transcriptional regulator QX56_RS18700 ENOG4105Y7X Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity) QX56_RS18705 ENOG4106YAD MORN repeat variant QX56_RS18725 ENOG4108XI2 Domain of unknown function (DUF1963) QX56_RS18730 ENOG4105C6Y Udp-glucose 6-dehydrogenase QX56_RS18735 ENOG4108RB3 Capsular polysaccharide biosynthesis protein QX56_RS18740 ENOG4107YJ4 chain length determinant protein QX56_RS18745 ENOG4105HTX biosynthesis protein QX56_RS18750 ENOG4105KBK Zinc finger, swim domain protein QX56_RS18755 ENOG4105C0D helicase QX56_RS18760 ENOG410667J hydrolase QX56_RS18765 ENOG4105E98 transcriptional regulator DeoR family QX56_RS18770 ENOG4105Z8H single-stranded DNA-binding protein QX56_RS18795 ENOG4105M2E Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity) QX56_RS18800 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) QX56_RS18810 ENOG4105CGA flagellar basal-body rod protein FlgG QX56_RS18820 ENOG4105DFF Rod shape-determining protein mreb QX56_RS18825 ENOG4105MT0 Sporulation transcriptional regulator spoiiid QX56_RS18830 ENOG4107MII Sugar-specific transcriptional regulator TrmB QX56_RS18835 ENOG4105CZM Major Facilitator QX56_RS18840 ENOG4108M26 parallel beta-helix repeat protein QX56_RS18845 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease QX56_RS18850 ENOG41080V3 Major Facilitator superfamily QX56_RS18855 ENOG4105D3W isochorismatase QX56_RS18860 ENOG4107P26 QX56_RS18865 ENOG4105BZU Histidine kinase QX56_RS18875 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase QX56_RS18885 ENOG4105FRN stage II sporulation protein QX56_RS18890 ENOG4107TCE N-acetyltransferase QX56_RS18905 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) QX56_RS18910 ENOG4107TXC Transcriptional regulator QX56_RS18915 ENOG4106BRK QX56_RS18920 ENOG4108RYK Nad-dependent epimerase dehydratase QX56_RS18925 ENOG4108Z40 Transcriptional regulator QX56_RS18930 ENOG4105CQM Urea amidohydrolase subunit alpha QX56_RS18935 ENOG4105KI2 Urea amidohydrolase subunit beta QX56_RS18940 ENOG4108YZ9 Urea amidohydrolase subunit gamma QX56_RS18970 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) QX56_RS18975 ENOG4108TF4 von Willebrand factor, type A QX56_RS18990 ENOG4105JFG SpoIID LytB domain protein QX56_RS18995 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) QX56_RS19005 ENOG4106778 Protein of unknown function (DUF1146) QX56_RS19015 ENOG4105KNM Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) QX56_RS19020 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) QX56_RS19025 ENOG4105J80 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity) QX56_RS19030 ENOG4105CDG Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity) QX56_RS19050 ENOG4107RB6 it plays a direct role in the translocation of protons across the membrane (By similarity) QX56_RS19060 ENOG4105CZ5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity) QX56_RS19065 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) QX56_RS19070 ENOG4108UIC UPF0340 protein QX56_RS19075 ENOG4108YZG isomerase QX56_RS19080 ENOG4107WAU Protein tyrosine phosphatase QX56_RS19085 ENOG410815N Probably functions as a manganese efflux pump (By similarity) QX56_RS19090 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) QX56_RS19100 ENOG4108ZXQ stage ii sporulation protein r QX56_RS19115 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) QX56_RS19120 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) QX56_RS19125 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase QX56_RS19135 ENOG4107TT2 Auxin Efflux Carrier QX56_RS19140 ENOG4105C6K Malic enzyme QX56_RS19145 ENOG4107104 thymidine kinase QX56_RS19155 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) QX56_RS19160 ENOG4105CBT Fructose-1,6-bisphosphatase QX56_RS19165 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) QX56_RS19170 ENOG4107XMI Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway QX56_RS19175 ENOG4105D2N Aldolase QX56_RS19180 ENOG410812K response regulator receiver protein QX56_RS19190 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) QX56_RS19200 ENOG4105C1G acyl-Coa dehydrogenase QX56_RS19205 ENOG4105DF6 Fe-S oxidoreductase QX56_RS19215 ENOG4105E5J UV damage endonuclease QX56_RS19225 ENOG4105NAE bifunctional deaminase-reductase domain protein QX56_RS19230 ENOG4105BZ1 (ABC) transporter QX56_RS19235 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) QX56_RS19245 ENOG4105R3A Nitrate reductase QX56_RS19250 ENOG4108IUE nitrate reductase beta subunit QX56_RS19270 ENOG4107V6Q Cyclic nucleotide-binding domain QX56_RS19280 ENOG4105C75 arginyL-tRNA synthetase QX56_RS19285 ENOG410684U Domain of unknown function (DUF1934) QX56_RS19295 ENOG4105EZY Pyrroloquinoline quinone biosynthesis protein E QX56_RS19345 ENOG4107JM4 Tetratricopeptide repeat QX56_RS19355 ENOG4108UIN ybak prolyl-trna synthetase associated region QX56_RS19360 ENOG4105CYW agmatinase QX56_RS19365 ENOG4105CCX Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) QX56_RS19370 ENOG4105BZ4 penicillin-binding protein QX56_RS19375 ENOG4108XFG YwhD family QX56_RS19380 ENOG4108Z4T Peptidase M50 QX56_RS19385 ENOG41069HH 4-oxalocrotonate tautomerase QX56_RS19390 ENOG41067TZ transcriptional regulator, MarR family QX56_RS19395 ENOG4105C22 threonyL-tRNA synthetase QX56_RS19400 ENOG4105C57 major facilitator superfamily QX56_RS19405 ENOG41062ES Transcriptional regulator QX56_RS19415 ENOG4105DCI Phosphohydrolase QX56_RS19425 ENOG4108VCI transcription factor, rsfa family QX56_RS19430 ENOG4108RNG Permease of the drug metabolite transporter QX56_RS19435 ENOG4105JGI Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity) QX56_RS19440 ENOG4105DUM transcriptional regulator, lysR family QX56_RS19445 ENOG4108IJ2 phosphate acetyltransferase QX56_RS19460 ENOG4105CHM Aminotransferase QX56_RS19470 ENOG4108V3M Inherit from COG: acetyl-CoA carboxylase biotin carboxylase QX56_RS19475 ENOG4105CHR reductase QX56_RS19480 ENOG4106CHD Bacilysin biosynthesis protein bacB QX56_RS19485 ENOG41061WN bacilysin biosynthesis protein QX56_RS19490 ENOG4105FCW Major Facilitator superfamily QX56_RS19505 ENOG4105C26 Dehydrogenase QX56_RS19510 ENOG4105D82 Glutamate dehydrogenase QX56_RS19520 ENOG4107ZIM Dtdp-4-dehydrorhamnose 3,5-epimerase QX56_RS19525 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase QX56_RS19530 ENOG4105C1B dTDP-glucose 4-6-dehydratase QX56_RS19535 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) QX56_RS19540 ENOG4107P9E Inherit from COG: pseudaminic acid biosynthesis-associated protein PseG QX56_RS19545 ENOG4107TY6 Acylneuraminate cytidylyltransferase QX56_RS19555 ENOG41067MN Spore coat polysaccharide biosynthesis protein spsD QX56_RS19560 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase QX56_RS19600 ENOG4105C26 Dehydrogenase QX56_RS19605 ENOG4105D5S Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity) QX56_RS19610 ENOG4108RJ9 Glycosyl transferase, family 2 QX56_RS19630 ENOG4105DWF phosphomethylpyrimidine kinase QX56_RS19645 ENOG4105C5Y PTS System QX56_RS19650 ENOG4108QTI )-transporter QX56_RS19665 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin QX56_RS19670 ENOG4105DEN Luciferase family QX56_RS19675 ENOG4108DBC nitroreductase QX56_RS19690 ENOG41060D1 Quinol oxidase QX56_RS19695 ENOG4105CCU oxidase (Subunit III) QX56_RS19700 ENOG4105BZ9 Cytochrome C oxidase, subunit I QX56_RS19705 ENOG4105E2S oxidase) subunit II QX56_RS19710 ENOG4107BMA Transglycosylase associated protein QX56_RS19720 ENOG4105CRD Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity) QX56_RS19725 ENOG4105WH5 Teichoic acid glycosylation protein QX56_RS19750 ENOG4107ZXU DSBA oxidoreductase QX56_RS19755 ENOG4105DBE peroxidase QX56_RS19760 ENOG410650H (LipO)protein QX56_RS19765 ENOG4107SJW iron permease, FTR1 QX56_RS19770 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) QX56_RS19780 ENOG4105CMU LysR family (Transcriptional regulator QX56_RS19785 ENOG4105VAW lrga family QX56_RS19790 ENOG41067MG lrgb family QX56_RS19795 ENOG4105D8G Major Facilitator superfamily QX56_RS19805 ENOG4105DR4 Methyltransferase QX56_RS19815 ENOG4108YV3 Protein of unknown function (DUF2711) QX56_RS19820 ENOG4105CK1 PTS System QX56_RS19825 ENOG4105J8Z peptidase S8 and S53, subtilisin, kexin, sedolisin QX56_RS19840 ENOG4105X1N Glycosyl transferase family 8 QX56_RS19850 ENOG4105GVJ transcriptional regulator QX56_RS19855 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) QX56_RS19860 ENOG4105IIU Aminopeptidase QX56_RS19870 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase QX56_RS19880 ENOG4108IQD Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity) QX56_RS19885 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein QX56_RS19895 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD QX56_RS19900 ENOG4108VHC Short-chain dehydrogenase reductase Sdr QX56_RS19905 ENOG4105CM2 brancheD-chain amino acid aminotransferase QX56_RS19910 ENOG4105F8D glycoside hydrolase family 4 QX56_RS19915 ENOG4105VCP PTS System QX56_RS19920 ENOG4105CK1 PTS System QX56_RS19925 ENOG4105VZJ PTS System QX56_RS19930 ENOG4105EMD TRANSCRIPTIONal QX56_RS19935 ENOG4108VX5 3-methyladenine DNA glycosylase QX56_RS19940 ENOG4105CH6 catalase QX56_RS19955 ENOG4105DA5 (ABC) transporter QX56_RS19960 ENOG41069JR QX56_RS19980 ENOG4105ETS cytosine purines uracil thiamine allantoin QX56_RS19985 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) QX56_RS19990 ENOG4108JJ8 (ABC) transporter QX56_RS19995 ENOG4108JJ9 ABC, transporter QX56_RS20000 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii QX56_RS20005 ENOG4105C4M (Ubiquinol oxidase) subunit I QX56_RS20010 ENOG4105D2K citrate carrier protein QX56_RS20025 ENOG4107BJW polysaccharide deacetylase QX56_RS20045 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) QX56_RS20055 ENOG4105CMR udp-glucose 4-epimerase QX56_RS20060 ENOG4105KIS phospholipid-binding protein QX56_RS20065 ENOG4108WAV Transcriptional regulator QX56_RS20075 ENOG4105BZU Histidine kinase QX56_RS20080 ENOG4105WH1 Two component transcriptional regulator luxr family QX56_RS20085 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) QX56_RS20110 ENOG4105DTD Dehydrogenase QX56_RS20115 ENOG4108IIH CoA-transferase subunit B QX56_RS20120 ENOG4105D6N CoA-transferase, subunit a QX56_RS20125 ENOG4105CY2 Citrate transporter QX56_RS20130 ENOG4105DHI Methyltransferase QX56_RS20155 ENOG4105CH6 catalase QX56_RS20160 ENOG4105D4T Citrate transporter QX56_RS20165 ENOG4108RZ2 Glycoside hydrolase family 16 QX56_RS20170 ENOG4105CID antiterminator QX56_RS20185 ENOG4105C1J atp-dependent rna helicase QX56_RS20190 ENOG4107TDE lipolytic protein G-D-S-L family QX56_RS20240 ENOG4105CNA YD repeat protein QX56_RS20250 ENOG4107YZX Universal stress protein QX56_RS20255 ENOG4105CS2 ec 3.2.1.21 QX56_RS20260 ENOG4105C5Y PTS System QX56_RS20275 ENOG4107EV6 Inherit from COG: YD repeat protein QX56_RS20290 ENOG4106Z5D Glycoside Hydrolase Family 43 QX56_RS20300 ENOG4105C84 Histidine ammonia-lyase QX56_RS20305 ENOG4105CGP Urocanate hydratase QX56_RS20310 ENOG4105CI2 imidazolone-5-propionate hydrolase QX56_RS20315 ENOG4107W25 arginase agmatinase formiminoglutamase QX56_RS20325 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) QX56_RS20330 ENOG4105D9N nucleoside QX56_RS20340 ENOG4107RHR regulatoR QX56_RS20345 ENOG4108TM9 integral membrane protein QX56_RS20350 ENOG4105ENY Ethanolamine utilization protein eutH QX56_RS20355 ENOG4108PGP mmge prpd family protein QX56_RS20370 ENOG4108HW4 amino acid AbC transporter QX56_RS20375 ENOG4105EAB amino acid AbC transporter QX56_RS20395 ENOG4107QHE Choloylglycine hydrolase QX56_RS20400 ENOG410667J hydrolase QX56_RS20430 ENOG4108V5C ABC transporter QX56_RS20460 ENOG4105D2N Aldolase QX56_RS20465 ENOG4107TRN Xylose isomerase domain protein TIM barrel QX56_RS20470 ENOG4105F0H myo-inositol catabolism protein QX56_RS20475 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) QX56_RS20485 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) QX56_RS20490 ENOG4108HRG Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity) QX56_RS20495 ENOG4105D7K pfkb domain protein QX56_RS20500 ENOG4105DH8 myo-inositol catabolism QX56_RS20505 ENOG4105C26 Dehydrogenase QX56_RS20515 ENOG4105CPC Aldo Keto reductase QX56_RS20530 ENOG4107QNK )-transporter QX56_RS20535 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) QX56_RS20545 ENOG41061TZ Short-chain dehydrogenase reductase Sdr QX56_RS20550 ENOG4105ST3 Transcriptional regulator QX56_RS20555 ENOG4105C26 Dehydrogenase QX56_RS20560 ENOG4108YM7 Gcn5-related n-acetyltransferase QX56_RS20565 ENOG4105N1N Cupin superfamily protein QX56_RS20570 ENOG4107Y1Y Methyltransferase QX56_RS20585 ENOG4105CAQ asparagine synthetase QX56_RS20590 ENOG4105F22 Major Facilitator Superfamily QX56_RS20595 ENOG4108ITS PQQ enzyme repeat QX56_RS20605 ENOG41085PJ rdd domain containing protein QX56_RS20620 ENOG4105J7D transcriptional regulator QX56_RS20625 ENOG4107JEE Short-chain dehydrogenase reductase Sdr QX56_RS20630 ENOG41061AU MarR family Transcriptional regulator QX56_RS20640 ENOG41067MG lrgb family QX56_RS20650 ENOG4105BZW Glycerate kinase QX56_RS20655 ENOG4105G3Z GntR family transcriptional regulator QX56_RS20660 ENOG4105CMG Carbohydrate kinase QX56_RS20665 ENOG4105C6Z Gluconate QX56_RS20670 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) QX56_RS20675 ENOG4105D3R alkyl hydroperoxide reductase QX56_RS20680 ENOG4108JU3 Alkyl hydroperoxide reductase QX56_RS20685 ENOG4105CS2 ec 3.2.1.21 QX56_RS20695 ENOG4108S3Y transcriptional regulator QX56_RS20705 ENOG4106KKU QX56_RS20710 ENOG4108Z15 abc transporter atp-binding protein QX56_RS20720 ENOG4105Y2Z radical SAM domain protein QX56_RS20730 ENOG4105DMC D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3 QX56_RS20745 ENOG41069I7 QX56_RS20750 ENOG4108UXA Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity) QX56_RS20760 ENOG4105E2A Dehydrogenase QX56_RS20780 ENOG4105NUN Orthopoxvirus protein of unknown function (DUF830) QX56_RS20785 ENOG4105WQG acetyltransferase QX56_RS20790 ENOG410780I phosphoprotein phosphatase activity QX56_RS20800 ENOG41066UZ arginase EC 3.5.3.1 QX56_RS20805 ENOG4108IQI permease QX56_RS20810 ENOG4105C8Y Acetylornithine aminotransferase QX56_RS20815 ENOG4108JUB Transcriptional regulator QX56_RS20825 ENOG4105C0H protease QX56_RS20830 ENOG4105Q2H domain protein QX56_RS20845 ENOG4105BZU Histidine kinase QX56_RS20850 ENOG4105CK6 Two component transcriptional regulator (Winged helix family QX56_RS20875 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis QX56_RS20880 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase QX56_RS20885 ENOG4105CDU Replicative dna helicase QX56_RS20900 ENOG4105DJ2 Major Facilitator Superfamily QX56_RS20905 ENOG4105EDW glycosyl transferase, family 39 QX56_RS20910 ENOG4105K9Q Binds to the 23S rRNA (By similarity) QX56_RS20915 ENOG4105BZR domain protein QX56_RS20920 ENOG4108XMW Membrane QX56_RS20935 ENOG4105KVH Transcriptional regulator QX56_RS20940 ENOG4105E2M Manganese-dependent inorganic pyrophosphatase QX56_RS20970 ENOG41060CM Protein of unknown function (DUF2712) QX56_RS20975 ENOG4106NWU QX56_RS20980 ENOG41064J9 QX56_RS20985 ENOG41064SH Protein of unknown function (DUF2705) QX56_RS20990 ENOG4108RDQ ABC transporter QX56_RS21000 ENOG4108VSZ Inherit from COG: ketosteroid isomerase-like protein QX56_RS21005 ENOG4105DDN Pentapeptide repeat-containing protein QX56_RS21010 ENOG4105D94 Major Facilitator Superfamily QX56_RS21015 ENOG4107RSM transcriptional regulator QX56_RS21020 ENOG41082BV acetyltransferase QX56_RS21025 ENOG41081I9 integral membrane protein QX56_RS21035 ENOG4108U05 Transcriptional regulator QX56_RS21040 ENOG41082BV acetyltransferase QX56_RS21050 ENOG4108U7W acetyltransferase QX56_RS21055 ENOG4105UNS Pfam:DUF419 QX56_RS21060 ENOG4105NAE bifunctional deaminase-reductase domain protein QX56_RS21065 ENOG4108J8C transporter major facilitator family protein QX56_RS21080 ENOG4108IPJ Membrane QX56_RS21085 ENOG4105C7Z Conserved Protein QX56_RS21090 ENOG4107FCW Abortive infection protein QX56_RS21100 ENOG4108UW5 maltose o-acetyltransferase QX56_RS21105 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase QX56_RS21115 ENOG4105CGK Exodeoxyribonuclease III QX56_RS21120 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) QX56_RS21125 ENOG4108UUM single-stranded DNA-binding protein QX56_RS21130 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) QX56_RS21135 ENOG4105C3G gtp-binding protein QX56_RS21140 ENOG4108J2R molybdopterin oxidoreductase QX56_RS21145 ENOG4105VDK protein, conserved in bacteria QX56_RS21155 ENOG4108ZDA Sporulation protein YyaC QX56_RS21160 ENOG4105FA0 parb-like partition protein QX56_RS21165 ENOG4107QJE Chromosome Partitioning Protein QX56_RS21180 ENOG4105D28 Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity) QX56_RS21185 ENOG4107RE5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) QX56_RS21190 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) QX56_RS21205 ENOG4105M7T RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity) QX56_RS21220 ENOG4107S45 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) QX56_RS21460 ENOG4106AXD QX56_RS21465 ENOG4105VWP Inherit from COG: 4Fe-4S ferredoxin, iron-sulfur binding QX56_RS21810 ENOG4105YAC QX56_RS22150 ENOG4107SJB teichoic acid biosynthesis QX56_RS22250 ENOG4105C5Y PTS System