locus-tag	class	description
GAY71_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GAY71_RS00010	COG0592	DNA-directed DNA polymerase activity
GAY71_RS00015	COG2501	S4 domain
GAY71_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GAY71_RS00030	COG0187	DNA topoisomerase II activity
GAY71_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GAY71_RS00070	COG0517	IMP dehydrogenase activity
GAY71_RS00070	COG0516	GMP reductase activity
GAY71_RS00075	COG1686	Belongs to the peptidase S11 family
GAY71_RS00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GAY71_RS00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GAY71_RS00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GAY71_RS00100	COG1428	Deoxynucleoside kinase
GAY71_RS00105	COG1428	Deoxynucleoside kinase
GAY71_RS00110	COG3858	chitin binding
GAY71_RS00110	COG1388	LysM domain
GAY71_RS00115	COG1335	isochorismatase
GAY71_RS00120	COG0590	tRNA wobble adenosine to inosine editing
GAY71_RS00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GAY71_RS00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GAY71_RS00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GAY71_RS00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
GAY71_RS00190	COG3853	Toxic anion resistance protein (TelA)
GAY71_RS00195	COG1982	Orn Lys Arg decarboxylase major
GAY71_RS00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GAY71_RS00205	COG3870	Protein conserved in bacteria
GAY71_RS00210	COG1728	Protein conserved in bacteria
GAY71_RS00215	COG0470	DNA polymerase III
GAY71_RS00220	COG1774	PSP1 C-terminal conserved region
GAY71_RS00225	COG4467	Involved in initiation control of chromosome replication
GAY71_RS00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GAY71_RS00235	COG2827	Endonuclease containing a URI domain
GAY71_RS00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GAY71_RS00245	COG2002	toxin-antitoxin pair type II binding
GAY71_RS00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GAY71_RS00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GAY71_RS00255	COG0084	hydrolase, TatD family'
GAY71_RS00260	COG3584	3D domain protein
GAY71_RS00260	COG3583	domain protein
GAY71_RS00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GAY71_RS00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GAY71_RS00280	COG4466	Protein conserved in bacteria
GAY71_RS00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GAY71_RS00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GAY71_RS00300	COG0251	oxidation-reduction process
GAY71_RS00305	COG2088	sporulation resulting in formation of a cellular spore
GAY71_RS00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GAY71_RS00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GAY71_RS00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GAY71_RS00325	COG0193	aminoacyl-tRNA hydrolase activity
GAY71_RS00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GAY71_RS00340	COG2002	toxin-antitoxin pair type II binding
GAY71_RS00345	COG2244	polysaccharide biosynthetic process
GAY71_RS00350	COG3956	TIGRFAM MazG family protein
GAY71_RS00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GAY71_RS00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GAY71_RS00375	COG1098	S1 RNA binding domain
GAY71_RS00390	COG2208	phosphoserine phosphatase activity
GAY71_RS00395	COG2304	oxidoreductase activity
GAY71_RS00400	COG0515	serine threonine protein kinase
GAY71_RS00405	COG0037	tRNA processing
GAY71_RS00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GAY71_RS00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GAY71_RS00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GAY71_RS00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GAY71_RS00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GAY71_RS00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GAY71_RS00445	COG0512	Glutamine amidotransferase of anthranilate synthase
GAY71_RS00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GAY71_RS00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GAY71_RS00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GAY71_RS00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GAY71_RS00470	COG1396	sequence-specific DNA binding
GAY71_RS00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GAY71_RS00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GAY71_RS00560	COG4463	regulation of RNA biosynthetic process
GAY71_RS00565	COG3880	PFAM UvrB UvrC protein
GAY71_RS00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
GAY71_RS00575	COG0542	response to heat
GAY71_RS00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GAY71_RS00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
GAY71_RS00590	COG4956	integral membrane protein (PIN domain superfamily)
GAY71_RS00595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GAY71_RS00600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GAY71_RS00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GAY71_RS00610	COG1045	serine acetyltransferase
GAY71_RS00615	COG0215	cysteine-tRNA ligase activity
GAY71_RS00620	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GAY71_RS00625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GAY71_RS00630	COG3688	RNA-binding protein containing a PIN domain
GAY71_RS00635	COG1595	DNA-templated transcription, initiation
GAY71_RS00640	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GAY71_RS00645	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GAY71_RS00650	COG0250	Participates in transcription elongation, termination and antitermination
GAY71_RS00655	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GAY71_RS00660	COG0081	regulation of translation
GAY71_RS00665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GAY71_RS00670	COG0222	ribosome binding
GAY71_RS00675	COG2813	Specifically methylates the guanine in position
GAY71_RS00680	COG0085	RNA polymerase activity
GAY71_RS00685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GAY71_RS00690	COG1358	cellular component organization or biogenesis
GAY71_RS00695	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GAY71_RS00700	COG0049	tRNA binding
GAY71_RS00705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GAY71_RS00710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GAY71_RS00715	COG0596	Alpha beta hydrolase
GAY71_RS00720	COG0051	transcription antitermination factor activity, RNA binding
GAY71_RS00725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GAY71_RS00730	COG0088	Forms part of the polypeptide exit tunnel
GAY71_RS00735	COG0089	rRNA binding
GAY71_RS00740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GAY71_RS00745	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GAY71_RS00750	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GAY71_RS00755	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GAY71_RS00760	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GAY71_RS00765	COG0255	Belongs to the universal ribosomal protein uL29 family
GAY71_RS00770	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GAY71_RS00775	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GAY71_RS00785	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GAY71_RS00795	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GAY71_RS00800	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GAY71_RS00805	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GAY71_RS00810	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GAY71_RS00815	COG1841	ribosomal large subunit assembly
GAY71_RS00820	COG0200	Binds to the 23S rRNA
GAY71_RS00825	COG0201	protein transport
GAY71_RS00830	COG0563	adenylate kinase activity
GAY71_RS00835	COG0024	Methionine aminopeptidase
GAY71_RS00840	COG2163	COG2163 Ribosomal protein L14E L6E L27E
GAY71_RS00845	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GAY71_RS00850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GAY71_RS00855	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GAY71_RS00860	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GAY71_RS00865	COG0202	RNA polymerase activity
GAY71_RS00870	COG0203	ribosomal protein L17
GAY71_RS00875	COG1122	ATPase activity
GAY71_RS00880	COG1122	ATPase activity
GAY71_RS00885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GAY71_RS00890	COG0101	tRNA pseudouridine synthase activity
GAY71_RS00895	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GAY71_RS00900	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GAY71_RS00905	COG2226	methyltransferase
GAY71_RS00915	COG0860	N-Acetylmuramoyl-L-alanine amidase
GAY71_RS00920	COG0489	protein tyrosine kinase activity
GAY71_RS00930	COG2194	sulfuric ester hydrolase activity
GAY71_RS00935	COG0726	polysaccharide deacetylase
GAY71_RS01015	COG0659	secondary active sulfate transmembrane transporter activity
GAY71_RS01020	COG0385	Bile acid
GAY71_RS01025	COG2819	hydrolase of the alpha beta superfamily
GAY71_RS01030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GAY71_RS01035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GAY71_RS01040	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GAY71_RS01045	COG2207	Transcriptional regulator
GAY71_RS01045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GAY71_RS01050	COG3876	Protein conserved in bacteria
GAY71_RS01055	COG1472	Belongs to the glycosyl hydrolase 3 family
GAY71_RS01060	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GAY71_RS01065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GAY71_RS01065	COG1263	PTS System
GAY71_RS01070	COG1737	Transcriptional regulator
GAY71_RS01075	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GAY71_RS01080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GAY71_RS01085	COG1683	Conserved Protein
GAY71_RS01115	COG1595	DNA-templated transcription, initiation
GAY71_RS01120	COG5662	AntiSigma factor
GAY71_RS01125	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GAY71_RS01130	COG4856	YbbR-like protein
GAY71_RS01135	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GAY71_RS01140	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GAY71_RS01150	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GAY71_RS01155	COG2169	Transcriptional regulator
GAY71_RS01160	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GAY71_RS01165	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GAY71_RS01170	COG3002	Belongs to the UPF0753 family
GAY71_RS01175	COG0288	reversible hydration of carbon dioxide
GAY71_RS01185	COG5609	conserved protein (DUF2294)
GAY71_RS01190	COG0640	Transcriptional regulator
GAY71_RS01195	COG2814	Major facilitator Superfamily
GAY71_RS01200	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GAY71_RS01210	COG0535	radical SAM domain protein
GAY71_RS01215	COG1266	CAAX protease self-immunity
GAY71_RS01220	COG1131	(ABC) transporter
GAY71_RS01230	COG1413	lyase activity
GAY71_RS01235	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GAY71_RS01240	COG0596	Alpha beta hydrolase
GAY71_RS01245	COG0745	RESPONSE REGULATOR receiver
GAY71_RS01250	COG0642	Histidine kinase
GAY71_RS01260	COG0515	serine threonine protein kinase
GAY71_RS01275	COG1113	amino acid transport
GAY71_RS01290	COG2602	Beta-lactamase
GAY71_RS01295	COG2124	cytochrome p450
GAY71_RS01305	COG0531	amino acid
GAY71_RS01310	COG0584	glycerophosphoryl diester phosphodiesterase
GAY71_RS01315	COG2271	Major facilitator Superfamily
GAY71_RS01325	COG1846	Transcriptional regulator
GAY71_RS01325	COG0456	acetyltransferase
GAY71_RS01330	COG2271	Major facilitator Superfamily
GAY71_RS01345	COG3409	Peptidoglycan-binding domain 1 protein
GAY71_RS01350	COG0697	spore germination
GAY71_RS01355	COG2207	Transcriptional regulator
GAY71_RS01355	COG1917	Cupin 2, conserved barrel domain protein
GAY71_RS01360	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GAY71_RS01365	COG3591	Belongs to the peptidase S1B family
GAY71_RS01375	COG0596	Alpha beta hydrolase
GAY71_RS01380	COG1183	phosphatidylcholine synthase activity
GAY71_RS01385	COG0586	Pfam SNARE associated Golgi protein
GAY71_RS01390	COG0688	phosphatidylethanolamine metabolic process
GAY71_RS01400	COG2312	Erythromycin esterase
GAY71_RS01405	COG2207	Transcriptional regulator
GAY71_RS01415	COG1301	dicarboxylic acid transport
GAY71_RS01420	COG2190	(PTS) system
GAY71_RS01420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GAY71_RS01420	COG1263	PTS System
GAY71_RS01425	COG0363	glucosamine-6-phosphate deaminase activity
GAY71_RS01440	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GAY71_RS01445	COG0833	amino acid
GAY71_RS01450	COG2040	homocysteine
GAY71_RS01460	COG1115	amino acid carrier protein
GAY71_RS01465	COG2066	Belongs to the glutaminase family
GAY71_RS01470	COG4191	Histidine kinase
GAY71_RS01475	COG0784	Response regulator, receiver
GAY71_RS01480	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GAY71_RS01485	COG1012	belongs to the aldehyde dehydrogenase family
GAY71_RS01490	COG2271	Major facilitator Superfamily
GAY71_RS01495	COG4948	Mandelate Racemase Muconate Lactonizing
GAY71_RS01500	COG2186	Transcriptional regulator
GAY71_RS01505	COG2721	sulfolactate sulfo-lyase activity
GAY71_RS01510	COG3173	Aminoglycoside phosphotransferase
GAY71_RS01520	COG0697	spore germination
GAY71_RS01525	COG0745	RESPONSE REGULATOR receiver
GAY71_RS01530	COG2205	protein histidine kinase activity
GAY71_RS01535	COG1131	(ABC) transporter
GAY71_RS01555	COG3773	Cell wall hydrolase
GAY71_RS01560	COG2304	oxidoreductase activity
GAY71_RS01570	COG3540	Alkaline phosphatase
GAY71_RS01575	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GAY71_RS01580	COG0805	protein transport
GAY71_RS01585	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GAY71_RS01590	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GAY71_RS01595	COG0477	Major facilitator Superfamily
GAY71_RS01600	COG1309	transcriptional regulator
GAY71_RS01605	COG0252	asparaginase activity
GAY71_RS01610	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GAY71_RS01615	COG1714	RDD family
GAY71_RS01620	COG1405	negative regulation of cell septum assembly
GAY71_RS01620	COG3012	SEC-C Motif Domain Protein
GAY71_RS01625	COG3290	protein histidine kinase activity
GAY71_RS01630	COG3279	Response regulator of the LytR AlgR family
GAY71_RS01635	COG4555	ABC transporter
GAY71_RS01640	COG1668	transmembrane transport
GAY71_RS01645	COG0667	Aldo Keto reductase
GAY71_RS01660	COG1595	DNA-templated transcription, initiation
GAY71_RS01665	COG1595	DNA-templated transcription, initiation
GAY71_RS01670	COG1876	peptidase activity
GAY71_RS01675	COG0457	Tetratricopeptide repeat
GAY71_RS01680	COG1028	Short-chain dehydrogenase reductase Sdr
GAY71_RS01685	COG0366	Alpha amylase catalytic
GAY71_RS01690	COG0803	Belongs to the bacterial solute-binding protein 9 family
GAY71_RS01695	COG1121	(ABC) transporter
GAY71_RS01700	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GAY71_RS01705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GAY71_RS01710	COG2310	stress, protein
GAY71_RS01715	COG2310	stress, protein
GAY71_RS01720	COG2310	stress, protein
GAY71_RS01725	COG0861	Integral membrane protein TerC family
GAY71_RS01735	COG3853	Toxic anion resistance protein (TelA)
GAY71_RS01740	COG0477	Major facilitator Superfamily
GAY71_RS01745	COG2814	Major facilitator Superfamily
GAY71_RS01750	COG0640	Transcriptional regulator
GAY71_RS01755	COG4175	Glycine betaine
GAY71_RS01755	COG0517	IMP dehydrogenase activity
GAY71_RS01760	COG4176	ABC-type proline glycine betaine transport system permease component
GAY71_RS01765	COG2113	Glycine betaine
GAY71_RS01770	COG1473	amidohydrolase
GAY71_RS01775	COG1288	antiporter activity
GAY71_RS01785	COG0366	Alpha amylase catalytic
GAY71_RS01790	COG0039	L-malate dehydrogenase activity
GAY71_RS01795	COG1620	l-lactate permease
GAY71_RS01800	COG2814	Major facilitator Superfamily
GAY71_RS01805	COG1846	Transcriptional regulator
GAY71_RS01810	COG1280	lysine exporter protein (LysE YggA)
GAY71_RS01815	COG3403	YqcI/YcgG family
GAY71_RS01820	COG1113	amino acid transport
GAY71_RS01825	COG3665	Urea carboxylase-associated protein
GAY71_RS01830	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GAY71_RS01835	COG1660	Displays ATPase and GTPase activities
GAY71_RS01840	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GAY71_RS01845	COG2226	methyltransferase
GAY71_RS01850	COG0583	DNA-binding transcription factor activity
GAY71_RS01855	COG3458	cephalosporin-C deacetylase activity
GAY71_RS01860	COG3541	Predicted nucleotidyltransferase
GAY71_RS01865	COG0506	proline dehydrogenase activity
GAY71_RS01870	COG1012	belongs to the aldehyde dehydrogenase family
GAY71_RS01880	COG2508	Transcriptional regulator
GAY71_RS01885	COG3689	TIGRFAM TIGR03943 family protein
GAY71_RS01890	COG0701	Predicted permease
GAY71_RS01895	COG2267	carboxylic ester hydrolase activity
GAY71_RS01900	COG0492	ferredoxin-NADP+ reductase activity
GAY71_RS01905	COG1587	Uroporphyrinogen-III synthase
GAY71_RS01905	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GAY71_RS01910	COG2146	nitrite reductase [NAD(P)H] activity
GAY71_RS01915	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GAY71_RS01920	COG0243	molybdopterin cofactor binding
GAY71_RS01925	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GAY71_RS01930	COG2223	nitrite transmembrane transporter activity
GAY71_RS01935	COG1469	GTP cyclohydrolase I activity
GAY71_RS01940	COG1376	ErfK ybiS ycfS ynhG family protein
GAY71_RS01950	COG0523	cobalamin synthesis protein
GAY71_RS01955	COG0765	amino acid transport
GAY71_RS01960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GAY71_RS01970	COG1714	RDD family
GAY71_RS01980	COG2723	6-phospho-beta-galactosidase activity
GAY71_RS01990	COG3209	COG3209 Rhs family protein
GAY71_RS01995	COG3290	protein histidine kinase activity
GAY71_RS01995	COG0840	transmembrane signaling receptor activity
GAY71_RS02000	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GAY71_RS02005	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
GAY71_RS02010	COG1733	regulation of RNA biosynthetic process
GAY71_RS02015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GAY71_RS02020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GAY71_RS02025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GAY71_RS02030	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
GAY71_RS02035	COG2814	Major facilitator Superfamily
GAY71_RS02045	COG0697	spore germination
GAY71_RS02050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GAY71_RS02060	COG2364	Membrane
GAY71_RS02065	COG1126	abc transporter atp-binding protein
GAY71_RS02070	COG0765	amino acid transport
GAY71_RS02075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GAY71_RS02080	COG0583	DNA-binding transcription factor activity
GAY71_RS02085	COG0163	prenyltransferase activity
GAY71_RS02090	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GAY71_RS02105	COG0596	Alpha beta hydrolase
GAY71_RS02110	COG3104	oligopeptide transport
GAY71_RS02115	COG5434	Belongs to the glycosyl hydrolase 28 family
GAY71_RS02125	COG0697	spore germination
GAY71_RS02135	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GAY71_RS02140	COG1136	(ABC) transporter
GAY71_RS02145	COG0577	efflux transmembrane transporter activity
GAY71_RS02150	COG0745	RESPONSE REGULATOR receiver
GAY71_RS02155	COG5002	protein histidine kinase activity
GAY71_RS02155	COG3850	Histidine kinase
GAY71_RS02160	COG0457	Tetratricopeptide repeat
GAY71_RS02180	COG0527	aspartate kinase activity
GAY71_RS02185	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GAY71_RS02190	COG4605	iron ion homeostasis
GAY71_RS02195	COG4604	ABC transporter, ATP-binding protein
GAY71_RS02200	COG4607	ABC-type enterochelin transport system periplasmic component
GAY71_RS02205	COG2814	Major facilitator Superfamily
GAY71_RS02210	COG1309	transcriptional regulator
GAY71_RS02215	COG0778	Nitroreductase
GAY71_RS02220	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GAY71_RS02225	COG0640	Transcriptional regulator
GAY71_RS02230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GAY71_RS02235	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GAY71_RS02240	COG1012	belongs to the aldehyde dehydrogenase family
GAY71_RS02245	COG4975	Glucose uptake
GAY71_RS02250	COG1028	Short-chain dehydrogenase reductase Sdr
GAY71_RS02255	COG4549	nuclear export factor GLE1
GAY71_RS02260	COG2372	response to copper ion
GAY71_RS02260	COG1276	copper resistance
GAY71_RS02265	COG1349	DNA-binding transcription factor activity
GAY71_RS02275	COG2213	PTS system mannitol-specific
GAY71_RS02280	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GAY71_RS02285	COG0246	Mannitol dehydrogenase
GAY71_RS02290	COG0473	3-isopropylmalate dehydrogenase activity
GAY71_RS02295	COG0681	Belongs to the peptidase S26 family
GAY71_RS02300	COG0412	Dienelactone hydrolase
GAY71_RS02305	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GAY71_RS02315	COG0561	phosphatase activity
GAY71_RS02320	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GAY71_RS02325	COG1914	H( )-stimulated, divalent metal cation uptake system
GAY71_RS02330	COG4336	lyase activity
GAY71_RS02335	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GAY71_RS02340	COG1984	allophanate hydrolase subunit 2
GAY71_RS02345	COG1414	Transcriptional regulator
GAY71_RS02350	COG2755	lipolytic protein G-D-S-L family
GAY71_RS02360	COG2329	Antibiotic biosynthesis monooxygenase
GAY71_RS02365	COG0768	penicillin binding
GAY71_RS02370	COG4989	oxidoreductase activity
GAY71_RS02375	COG3711	transcriptional antiterminator
GAY71_RS02380	COG0318	PFAM AMP-dependent synthetase and ligase
GAY71_RS02385	COG2226	methyltransferase
GAY71_RS02390	COG1028	Short-chain dehydrogenase reductase Sdr
GAY71_RS02395	COG1917	Cupin 2, conserved barrel domain protein
GAY71_RS02400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GAY71_RS02405	COG3871	stress protein (general stress protein 26)
GAY71_RS02415	COG2814	Major facilitator Superfamily
GAY71_RS02420	COG1522	sequence-specific DNA binding
GAY71_RS02425	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GAY71_RS02425	COG0551	DNA topoisomerase type I activity
GAY71_RS02430	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GAY71_RS02435	COG3706	GGDEF domain
GAY71_RS02440	COG5298	Protein conserved in bacteria
GAY71_RS02445	COG1215	transferase activity, transferring glycosyl groups
GAY71_RS02455	COG0531	amino acid
GAY71_RS02460	COG0494	nUDIX hydrolase
GAY71_RS02465	COG0028	Belongs to the TPP enzyme family
GAY71_RS02480	COG1914	H( )-stimulated, divalent metal cation uptake system
GAY71_RS02485	COG2261	transglycosylase associated protein
GAY71_RS02490	COG4876	unkown
GAY71_RS02495	COG2217	Heavy metal translocating P-type atpase
GAY71_RS02500	COG3729	General stress protein
GAY71_RS02505	COG0662	Cupin 2, conserved barrel domain protein
GAY71_RS02510	COG2329	Antibiotic biosynthesis monooxygenase
GAY71_RS02515	COG3546	catalase activity
GAY71_RS02520	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GAY71_RS02525	COG3290	protein histidine kinase activity
GAY71_RS02530	COG4565	transcriptional regulatory protein
GAY71_RS02535	COG1301	dicarboxylic acid transport
GAY71_RS02540	COG0628	permease
GAY71_RS02545	COG1131	(ABC) transporter
GAY71_RS02550	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GAY71_RS02560	COG1960	acyl-CoA dehydrogenase activity
GAY71_RS02575	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GAY71_RS02580	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GAY71_RS02585	COG1181	Belongs to the D-alanine--D-alanine ligase family
GAY71_RS02590	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GAY71_RS02595	COG0513	Belongs to the DEAD box helicase family
GAY71_RS02600	COG3402	PFAM membrane-flanked domain
GAY71_RS02605	COG3428	Bacterial PH domain
GAY71_RS02610	COG0705	Rhomboid family
GAY71_RS02615	COG0736	holo-[acyl-carrier-protein] synthase activity
GAY71_RS02620	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GAY71_RS02625	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GAY71_RS02630	COG0864	Transcriptional regulator
GAY71_RS02635	COG2337	Toxic component of a toxin-antitoxin (TA) module
GAY71_RS02640	COG1366	Belongs to the anti-sigma-factor antagonist family
GAY71_RS02645	COG1366	Belongs to the anti-sigma-factor antagonist family
GAY71_RS02650	COG2172	sigma factor antagonist activity
GAY71_RS02655	COG2208	phosphoserine phosphatase activity
GAY71_RS02660	COG1366	Belongs to the anti-sigma-factor antagonist family
GAY71_RS02665	COG2172	sigma factor antagonist activity
GAY71_RS02670	COG1191	sigma factor activity
GAY71_RS02675	COG2208	phosphoserine phosphatase activity
GAY71_RS02690	COG1673	EVE domain
GAY71_RS02695	COG1846	Transcriptional regulator
GAY71_RS02700	COG2183	response to ionizing radiation
GAY71_RS02710	COG3091	SprT-like family
GAY71_RS02750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GAY71_RS02755	COG1522	sequence-specific DNA binding
GAY71_RS02760	COG1522	sequence-specific DNA binding
GAY71_RS02765	COG1335	isochorismatase
GAY71_RS02770	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GAY71_RS02775	COG2814	Major facilitator Superfamily
GAY71_RS02795	COG0693	protein deglycase activity
GAY71_RS02800	COG1278	Cold shock
GAY71_RS02805	COG1329	Transcriptional regulator
GAY71_RS02815	COG2207	Transcriptional regulator
GAY71_RS02815	COG1917	Cupin 2, conserved barrel domain protein
GAY71_RS02820	COG0697	spore germination
GAY71_RS02825	COG3708	Transcriptional regulator
GAY71_RS02825	COG2207	Transcriptional regulator
GAY71_RS02830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GAY71_RS02835	COG0477	Major facilitator Superfamily
GAY71_RS02845	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
GAY71_RS02855	COG0697	spore germination
GAY71_RS02860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GAY71_RS02865	COG2030	dehydratase
GAY71_RS02870	COG3545	Serine hydrolase
GAY71_RS02875	COG1733	regulation of RNA biosynthetic process
GAY71_RS02880	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GAY71_RS02885	COG1733	regulation of RNA biosynthetic process
GAY71_RS02890	COG2249	NAD(P)H dehydrogenase (quinone) activity
GAY71_RS02895	COG2814	Major facilitator Superfamily
GAY71_RS02900	COG1309	transcriptional regulator
GAY71_RS02910	COG0640	Transcriptional regulator
GAY71_RS02915	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GAY71_RS02925	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GAY71_RS02930	COG0697	spore germination
GAY71_RS02935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GAY71_RS02940	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GAY71_RS02945	COG0640	Transcriptional regulator
GAY71_RS02950	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GAY71_RS02965	COG4585	Histidine kinase
GAY71_RS02970	COG2197	response regulator
GAY71_RS02975	COG2409	Drug exporters of the RND superfamily
GAY71_RS02980	COG0596	Alpha beta hydrolase
GAY71_RS02985	COG1811	Na channel or pump
GAY71_RS02990	COG4978	Transcriptional regulator
GAY71_RS02990	COG0789	Transcriptional regulator
GAY71_RS02995	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GAY71_RS03000	COG0778	Nitroreductase
GAY71_RS03005	COG0346	lactoylglutathione lyase activity
GAY71_RS03010	COG2259	Doxx family
GAY71_RS03015	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GAY71_RS03030	COG2323	membrane
GAY71_RS03035	COG2323	membrane
GAY71_RS03040	COG0071	Belongs to the small heat shock protein (HSP20) family
GAY71_RS03055	COG1309	transcriptional regulator
GAY71_RS03065	COG0456	acetyltransferase
GAY71_RS03075	COG1113	amino acid transport
GAY71_RS03080	COG2318	DinB family
GAY71_RS03085	COG1846	Transcriptional regulator
GAY71_RS03090	COG2409	Drug exporters of the RND superfamily
GAY71_RS03090	COG1033	growth of symbiont in host cell
GAY71_RS03095	COG0778	Nitroreductase
GAY71_RS03100	COG1846	Transcriptional regulator
GAY71_RS03105	COG2814	Major facilitator Superfamily
GAY71_RS03110	COG0730	response to heat
GAY71_RS03115	COG1802	Transcriptional regulator
GAY71_RS03120	COG1388	LysM domain
GAY71_RS03120	COG3858	chitin binding
GAY71_RS03125	COG1819	glycosyl
GAY71_RS03135	COG1785	Belongs to the alkaline phosphatase family
GAY71_RS03140	COG5646	InterPro IPR014922
GAY71_RS03150	COG0454	-acetyltransferase
GAY71_RS03155	COG1078	dGTPase activity
GAY71_RS03160	COG1388	LysM domain
GAY71_RS03165	COG2814	Major facilitator Superfamily
GAY71_RS03170	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GAY71_RS03175	COG1447	Phosphotransferase system cellobiose-specific component IIA
GAY71_RS03180	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GAY71_RS03185	COG2723	6-phospho-beta-galactosidase activity
GAY71_RS03190	COG2188	Transcriptional regulator
GAY71_RS03195	COG1940	carbohydrate kinase activity
GAY71_RS03200	COG1482	cell wall glycoprotein biosynthetic process
GAY71_RS03205	COG4124	Belongs to the glycosyl hydrolase 26 family
GAY71_RS03250	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GAY71_RS03255	COG0802	atpase or kinase
GAY71_RS03260	COG1214	PFAM Peptidase M22, glycoprotease
GAY71_RS03265	COG0456	acetyltransferase
GAY71_RS03270	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GAY71_RS03275	COG0488	(ABC) transporter
GAY71_RS03280	COG0315	cyclic pyranopterin monophosphate synthase activity
GAY71_RS03285	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GAY71_RS03290	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GAY71_RS03295	COG0805	protein transport
GAY71_RS03305	COG1266	CAAX protease self-immunity
GAY71_RS03310	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GAY71_RS03315	COG0459	protein refolding
GAY71_RS03325	COG3378	Phage plasmid primase P4 family
GAY71_RS03340	COG0270	DNA (cytosine-5-)-methyltransferase activity
GAY71_RS03345	COG0270	DNA (cytosine-5-)-methyltransferase activity
GAY71_RS03365	COG1401	restriction endodeoxyribonuclease activity
GAY71_RS03380	COG1073	alpha beta
GAY71_RS03385	COG0457	Tetratricopeptide repeat
GAY71_RS03390	COG1063	alcohol dehydrogenase
GAY71_RS03395	COG2211	Major facilitator Superfamily
GAY71_RS03400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GAY71_RS03405	COG1842	Phage shock protein A
GAY71_RS03410	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GAY71_RS03415	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GAY71_RS03420	COG4260	virion core protein, lumpy skin disease virus
GAY71_RS03430	COG2814	Major facilitator Superfamily
GAY71_RS03435	COG1063	alcohol dehydrogenase
GAY71_RS03440	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GAY71_RS03445	COG0823	Involved in the tonB-independent uptake of proteins
GAY71_RS03460	COG2267	carboxylic ester hydrolase activity
GAY71_RS03470	COG2132	Multicopper oxidase
GAY71_RS03475	COG1113	amino acid transport
GAY71_RS03485	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GAY71_RS03490	COG0714	Associated with various cellular activities
GAY71_RS03495	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
GAY71_RS03500	COG1305	Transglutaminase-like
GAY71_RS03505	COG0519	Catalyzes the synthesis of GMP from XMP
GAY71_RS03505	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GAY71_RS03510	COG2252	PERMEase
GAY71_RS03515	COG3064	Membrane
GAY71_RS03525	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
GAY71_RS03535	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GAY71_RS03540	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GAY71_RS03545	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GAY71_RS03550	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GAY71_RS03555	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GAY71_RS03560	COG0047	phosphoribosylformylglycinamidine synthase activity
GAY71_RS03565	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GAY71_RS03570	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GAY71_RS03575	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GAY71_RS03580	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GAY71_RS03585	COG0138	bifunctional purine biosynthesis protein purh
GAY71_RS03590	COG0151	Belongs to the GarS family
GAY71_RS03595	COG1522	sequence-specific DNA binding
GAY71_RS03600	COG0531	amino acid
GAY71_RS03610	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GAY71_RS03615	COG1470	cell adhesion involved in biofilm formation
GAY71_RS03620	COG4496	protein, YerC YecD
GAY71_RS03625	COG0069	glutamate synthase activity
GAY71_RS03630	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
GAY71_RS03635	COG0210	DNA helicase
GAY71_RS03640	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GAY71_RS03645	COG4851	CamS sex pheromone cAM373 precursor
GAY71_RS03650	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GAY71_RS03655	COG1285	pathogenesis
GAY71_RS03660	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GAY71_RS03665	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GAY71_RS03670	COG0154	amidase activity
GAY71_RS03675	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GAY71_RS03680	COG1309	transcriptional regulator
GAY71_RS03685	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GAY71_RS03690	COG1597	lipid kinase activity
GAY71_RS03695	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GAY71_RS03700	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GAY71_RS03705	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GAY71_RS03710	COG1002	Type II restriction enzyme, methylase subunits
GAY71_RS03715	COG1061	Type III restriction enzyme res subunit
GAY71_RS03720	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GAY71_RS03740	COG5444	nuclease activity
GAY71_RS03745	COG3391	amine dehydrogenase activity
GAY71_RS03750	COG0457	Tetratricopeptide repeat
GAY71_RS03760	COG0217	transcriptional regulatory protein
GAY71_RS03770	COG1309	transcriptional regulator
GAY71_RS03775	COG3631	Ketosteroid isomerase-related protein
GAY71_RS03780	COG0702	epimerase
GAY71_RS03795	COG3546	catalase activity
GAY71_RS03800	COG0454	-acetyltransferase
GAY71_RS03810	COG5578	integral membrane protein
GAY71_RS03815	COG2972	Histidine kinase
GAY71_RS03820	COG4753	response regulator
GAY71_RS03820	COG2207	Transcriptional regulator
GAY71_RS03825	COG1653	transport
GAY71_RS03830	COG1175	transmembrane transport
GAY71_RS03835	COG0395	ABC-type sugar transport system, permease component
GAY71_RS03840	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GAY71_RS03845	COG2207	Transcriptional regulator
GAY71_RS03850	COG2755	lipolytic protein G-D-S-L family
GAY71_RS03860	COG5578	integral membrane protein
GAY71_RS03865	COG3401	FG-GAP repeat protein
GAY71_RS03870	COG3401	FG-GAP repeat protein
GAY71_RS03875	COG2755	lipolytic protein G-D-S-L family
GAY71_RS03880	COG1874	Beta-galactosidase
GAY71_RS03890	COG1653	transport
GAY71_RS03895	COG4209	transmembrane transport
GAY71_RS03900	COG0395	ABC-type sugar transport system, permease component
GAY71_RS03905	COG1486	melibiose metabolic process
GAY71_RS03910	COG2323	membrane
GAY71_RS03915	COG2329	Antibiotic biosynthesis monooxygenase
GAY71_RS03920	COG0346	lactoylglutathione lyase activity
GAY71_RS03935	COG5583	Uncharacterized small protein (DUF2292)
GAY71_RS03940	COG0670	Belongs to the BI1 family
GAY71_RS03945	COG0697	spore germination
GAY71_RS03950	COG1846	Transcriptional regulator
GAY71_RS03955	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GAY71_RS03965	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GAY71_RS03965	COG2124	cytochrome p450
GAY71_RS03970	COG1368	sulfuric ester hydrolase activity
GAY71_RS03975	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GAY71_RS03980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GAY71_RS03985	COG1442	glycosyl transferase family 8
GAY71_RS03990	COG1216	Glycosyl transferase, family 2
GAY71_RS03995	COG1442	glycosyl transferase family 8
GAY71_RS04000	COG2223	nitrite transmembrane transporter activity
GAY71_RS04005	COG1011	Hydrolase
GAY71_RS04010	COG0531	amino acid
GAY71_RS04015	COG1012	belongs to the aldehyde dehydrogenase family
GAY71_RS04020	COG0840	transmembrane signaling receptor activity
GAY71_RS04025	COG0488	(ABC) transporter
GAY71_RS04035	COG0789	Transcriptional regulator
GAY71_RS04040	COG2814	Major facilitator Superfamily
GAY71_RS04050	COG0488	(ABC) transporter
GAY71_RS04055	COG0513	Belongs to the DEAD box helicase family
GAY71_RS04060	COG0456	acetyltransferase
GAY71_RS04065	COG2130	NADP-dependent
GAY71_RS04070	COG2211	Major facilitator Superfamily
GAY71_RS04075	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GAY71_RS04080	COG1120	ATPase activity
GAY71_RS04085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GAY71_RS04090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GAY71_RS04095	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GAY71_RS04110	COG3866	Pectate lyase
GAY71_RS04115	COG0471	metal ion transport
GAY71_RS04120	COG3290	protein histidine kinase activity
GAY71_RS04125	COG4565	transcriptional regulatory protein
GAY71_RS04130	COG3181	Tripartite tricarboxylate transporter family receptor
GAY71_RS04135	COG2851	Citrate transporter
GAY71_RS04140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GAY71_RS04145	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
GAY71_RS04150	COG1254	Belongs to the acylphosphatase family
GAY71_RS04155	COG2258	MOSC domain
GAY71_RS04175	COG0024	Methionine aminopeptidase
GAY71_RS04180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GAY71_RS04180	COG1263	PTS System
GAY71_RS04185	COG1368	sulfuric ester hydrolase activity
GAY71_RS04200	COG1115	amino acid carrier protein
GAY71_RS04205	COG0531	amino acid
GAY71_RS04220	COG0697	spore germination
GAY71_RS04225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GAY71_RS04225	COG1263	PTS System
GAY71_RS04230	COG0366	Alpha amylase catalytic
GAY71_RS04235	COG2188	Transcriptional regulator
GAY71_RS04240	COG0778	Nitroreductase
GAY71_RS04245	COG0737	Belongs to the 5'-nucleotidase family
GAY71_RS04250	COG0693	protein deglycase activity
GAY71_RS04255	COG2814	Major facilitator Superfamily
GAY71_RS04260	COG4840	Belongs to the UPF0435 family
GAY71_RS04265	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GAY71_RS04270	COG4980	gas vesicle protein
GAY71_RS04275	COG1295	ribonuclease BN
GAY71_RS04280	COG0477	Major facilitator Superfamily
GAY71_RS04290	COG0387	Pfam Sodium calcium exchanger
GAY71_RS04300	COG0668	transmembrane transport
GAY71_RS04305	COG0535	radical SAM domain protein
GAY71_RS04315	COG0726	polysaccharide deacetylase
GAY71_RS04320	COG2084	Dehydrogenase
GAY71_RS04325	COG0598	Magnesium transport protein CorA
GAY71_RS04330	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GAY71_RS04335	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GAY71_RS04345	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GAY71_RS04350	COG4637	Psort location Cytoplasmic, score
GAY71_RS04360	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GAY71_RS04365	COG0022	dehydrogenase e1 component
GAY71_RS04370	COG0508	dehydrogenase complex catalyzes the overall conversion of
GAY71_RS04375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GAY71_RS04380	COG3284	Transcriptional regulator
GAY71_RS04390	COG1742	UPF0060 membrane protein
GAY71_RS04415	COG4842	Belongs to the WXG100 family
GAY71_RS04420	COG1486	melibiose metabolic process
GAY71_RS04425	COG1737	Transcriptional regulator
GAY71_RS04430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GAY71_RS04430	COG1263	PTS System
GAY71_RS04435	COG1132	(ABC) transporter
GAY71_RS04440	COG1132	(ABC) transporter
GAY71_RS04445	COG2259	Doxx family
GAY71_RS04450	COG2514	catechol 2,3-dioxygenase activity
GAY71_RS04455	COG1917	Cupin 2, conserved barrel domain protein
GAY71_RS04455	COG4977	sequence-specific DNA binding
GAY71_RS04460	COG2814	Major facilitator Superfamily
GAY71_RS04465	COG1082	Xylose isomerase domain protein TIM barrel
GAY71_RS04470	COG0673	inositol 2-dehydrogenase activity
GAY71_RS04475	COG4585	Histidine kinase
GAY71_RS04480	COG2197	response regulator
GAY71_RS04485	COG1131	(ABC) transporter
GAY71_RS04490	COG1511	domain protein
GAY71_RS04490	COG0842	Transport permease protein
GAY71_RS04495	COG0842	Transport permease protein
GAY71_RS04500	COG1695	Transcriptional regulator
GAY71_RS04505	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GAY71_RS04510	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
GAY71_RS04515	COG1309	transcriptional regulator
GAY71_RS04520	COG2814	Major facilitator Superfamily
GAY71_RS04525	COG2318	DinB family
GAY71_RS04530	COG2814	Major facilitator Superfamily
GAY71_RS04535	COG1846	Transcriptional regulator
GAY71_RS04540	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GAY71_RS04540	COG0392	lysyltransferase activity
GAY71_RS04545	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GAY71_RS04550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GAY71_RS04555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GAY71_RS04560	COG0384	phenazine biosynthesis protein PhzF
GAY71_RS04565	COG0778	Nitroreductase
GAY71_RS04580	COG1090	epimerase
GAY71_RS04585	COG2137	regulation of response to DNA damage stimulus
GAY71_RS04595	COG2814	Major facilitator Superfamily
GAY71_RS04610	COG3103	Sh3 type 3 domain protein
GAY71_RS04615	COG5658	integral membrane protein
GAY71_RS04620	COG0596	Alpha beta hydrolase
GAY71_RS04625	COG0463	Glycosyl transferase, family 2
GAY71_RS04630	COG4485	Bacterial membrane protein, YfhO
GAY71_RS04635	COG1988	membrane-bound metal-dependent
GAY71_RS04640	COG1194	a g-specific adenine glycosylase
GAY71_RS04650	COG1028	Short-chain dehydrogenase reductase Sdr
GAY71_RS04665	COG3557	Belongs to the UPF0374 family
GAY71_RS04670	COG1132	(ABC) transporter
GAY71_RS04675	COG4129	membrane
GAY71_RS04680	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GAY71_RS04685	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GAY71_RS04690	COG0735	belongs to the Fur family
GAY71_RS04800	COG4326	sporulation control protein
GAY71_RS04810	COG5577	PFAM Coat F domain
GAY71_RS04815	COG3340	Belongs to the peptidase S51 family
GAY71_RS04820	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GAY71_RS04825	COG0277	FAD linked oxidase domain protein
GAY71_RS04835	COG0753	catalase activity
GAY71_RS04840	COG1116	anion transmembrane transporter activity
GAY71_RS04845	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GAY71_RS04850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GAY71_RS04855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GAY71_RS04865	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GAY71_RS04875	COG1476	TRANSCRIPTIONal
GAY71_RS04885	COG3382	B3 4 domain protein
GAY71_RS04890	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GAY71_RS04900	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GAY71_RS04905	COG0789	Transcriptional regulator
GAY71_RS04910	COG1664	Polymer-forming cytoskeletal
GAY71_RS04915	COG1664	Polymer-forming cytoskeletal
GAY71_RS04920	COG2766	serine protein kinase
GAY71_RS04925	COG2718	Belongs to the UPF0229 family
GAY71_RS04930	COG1846	Transcriptional regulator
GAY71_RS04935	COG1566	PFAM secretion protein HlyD family protein
GAY71_RS04940	COG2814	Major facilitator Superfamily
GAY71_RS04945	COG0655	NAD(P)H dehydrogenase (quinone) activity
GAY71_RS04970	COG1131	(ABC) transporter
GAY71_RS04975	COG1131	(ABC) transporter
GAY71_RS04980	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GAY71_RS04985	COG1278	Cold shock
GAY71_RS04990	COG1464	Belongs to the NlpA lipoprotein family
GAY71_RS04995	COG3706	GGDEF domain
GAY71_RS05000	COG1823	symporter activity
GAY71_RS05020	COG5577	PFAM Coat F domain
GAY71_RS05025	COG1525	nuclease
GAY71_RS05025	COG4085	toxin activity
GAY71_RS05025	COG0737	Belongs to the 5'-nucleotidase family
GAY71_RS05030	COG3764	Sortase (surface protein transpeptidase)
GAY71_RS05035	COG0564	pseudouridine synthase activity
GAY71_RS05045	COG0517	IMP dehydrogenase activity
GAY71_RS05050	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GAY71_RS05055	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GAY71_RS05055	COG3153	acetyltransferase
GAY71_RS05060	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GAY71_RS05065	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GAY71_RS05070	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GAY71_RS05075	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GAY71_RS05080	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GAY71_RS05085	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GAY71_RS05090	COG4585	Histidine kinase
GAY71_RS05090	COG2203	Gaf domain
GAY71_RS05095	COG2197	response regulator
GAY71_RS05100	COG0431	NADPH-dependent FMN reductase
GAY71_RS05115	COG1388	LysM domain
GAY71_RS05115	COG0791	NLP P60 protein
GAY71_RS05120	COG1959	2 iron, 2 sulfur cluster binding
GAY71_RS05125	COG0668	transmembrane transport
GAY71_RS05130	COG2719	SpoVR family
GAY71_RS05135	COG1785	Belongs to the alkaline phosphatase family
GAY71_RS05140	COG1388	LysM domain
GAY71_RS05140	COG0791	NLP P60 protein
GAY71_RS05145	COG0583	DNA-binding transcription factor activity
GAY71_RS05150	COG0372	Belongs to the citrate synthase family
GAY71_RS05155	COG1028	Short-chain dehydrogenase reductase Sdr
GAY71_RS05160	COG0531	amino acid
GAY71_RS05165	COG0733	neurotransmitter:sodium symporter activity
GAY71_RS05170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GAY71_RS05175	COG0456	acetyltransferase
GAY71_RS05190	COG1595	DNA-templated transcription, initiation
GAY71_RS05195	COG0667	Aldo Keto reductase
GAY71_RS05200	COG0204	Acyl-transferase
GAY71_RS05205	COG1253	flavin adenine dinucleotide binding
GAY71_RS05210	COG0789	Transcriptional regulator
GAY71_RS05215	COG0436	Aminotransferase
GAY71_RS05220	COG1253	flavin adenine dinucleotide binding
GAY71_RS05225	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GAY71_RS05230	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GAY71_RS05235	COG0584	glycerophosphoryl diester phosphodiesterase
GAY71_RS05245	COG0668	transmembrane transport
GAY71_RS05250	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GAY71_RS05255	COG0726	polysaccharide deacetylase
GAY71_RS05260	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GAY71_RS05265	COG1757	Na H antiporter
GAY71_RS05270	COG0589	response to stress
GAY71_RS05280	COG1132	(ABC) transporter
GAY71_RS05285	COG1132	(ABC) transporter
GAY71_RS05290	COG0702	epimerase
GAY71_RS05310	COG0189	ligase activity
GAY71_RS05315	COG0189	ligase activity
GAY71_RS05320	COG4399	Belongs to the UPF0754 family
GAY71_RS05325	COG3679	Belongs to the UPF0342 family
GAY71_RS05330	COG4335	DNA alkylation repair
GAY71_RS05335	COG0561	phosphatase activity
GAY71_RS05340	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GAY71_RS05345	COG0475	glutathione-regulated potassium exporter activity
GAY71_RS05350	COG0490	domain, Protein
GAY71_RS05360	COG1024	Enoyl-CoA hydratase
GAY71_RS05370	COG4152	abc transporter atp-binding protein
GAY71_RS05375	COG1668	transmembrane transport
GAY71_RS05380	COG0420	3'-5' exonuclease activity
GAY71_RS05385	COG4717	serine-type aminopeptidase activity
GAY71_RS05390	COG3481	metal-dependent phosphohydrolase, HD sub domain
GAY71_RS05400	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GAY71_RS05430	COG1846	Transcriptional regulator
GAY71_RS05435	COG4980	gas vesicle protein
GAY71_RS05450	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GAY71_RS05455	COG0537	adenosine 5'-monophosphoramidase activity
GAY71_RS05460	COG1131	(ABC) transporter
GAY71_RS05465	COG4473	ABC transporter
GAY71_RS05475	COG1473	amidohydrolase
GAY71_RS05480	COG3069	C4-dicarboxylate transmembrane transporter activity
GAY71_RS05490	COG2329	Antibiotic biosynthesis monooxygenase
GAY71_RS05495	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GAY71_RS05500	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GAY71_RS05515	COG1309	transcriptional regulator
GAY71_RS05520	COG1511	domain protein
GAY71_RS05525	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GAY71_RS05530	COG4377	Putative membrane peptidase family (DUF2324)
GAY71_RS05540	COG1363	Peptidase, m42
GAY71_RS05545	COG4405	Protein conserved in bacteria
GAY71_RS05550	COG1301	dicarboxylic acid transport
GAY71_RS05560	COG1234	tRNA 3'-trailer cleavage
GAY71_RS05565	COG0095	Lipoate-protein ligase
GAY71_RS05570	COG0702	epimerase
GAY71_RS05575	COG0318	PFAM AMP-dependent synthetase and ligase
GAY71_RS05585	COG0501	Belongs to the peptidase M48B family
GAY71_RS05590	COG1404	Belongs to the peptidase S8 family
GAY71_RS05595	COG0456	acetyltransferase
GAY71_RS05600	COG0604	alcohol dehydrogenase
GAY71_RS05605	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GAY71_RS05610	COG0406	alpha-ribazole phosphatase activity
GAY71_RS05615	COG0183	Belongs to the thiolase family
GAY71_RS05620	COG0318	PFAM AMP-dependent synthetase and ligase
GAY71_RS05625	COG1268	BioY protein
GAY71_RS05630	COG0840	transmembrane signaling receptor activity
GAY71_RS05635	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GAY71_RS05635	COG0723	plastoquinol--plastocyanin reductase activity
GAY71_RS05640	COG1028	Short-chain dehydrogenase reductase Sdr
GAY71_RS05650	COG4903	ComK protein
GAY71_RS05655	COG1028	Short-chain dehydrogenase reductase Sdr
GAY71_RS05665	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GAY71_RS05680	COG0398	Pfam SNARE associated Golgi protein
GAY71_RS05685	COG0681	Belongs to the peptidase S26 family
GAY71_RS05690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GAY71_RS05695	COG1846	Transcriptional regulator
GAY71_RS05700	COG0738	Major facilitator superfamily
GAY71_RS05710	COG0561	phosphatase activity
GAY71_RS05715	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GAY71_RS05720	COG1609	Transcriptional regulator
GAY71_RS05725	COG3180	Ammonia monooxygenase
GAY71_RS05730	COG2814	Major facilitator Superfamily
GAY71_RS05730	COG0477	Major facilitator Superfamily
GAY71_RS05735	COG4533	DNA binding
GAY71_RS05745	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
GAY71_RS05750	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GAY71_RS05755	COG1074	ATP-dependent DNA helicase activity
GAY71_RS05760	COG0420	3'-5' exonuclease activity
GAY71_RS05765	COG0419	ATPase involved in DNA repair
GAY71_RS05770	COG1403	HNH endonuclease
GAY71_RS05810	COG5337	Spore coat protein CotH
GAY71_RS05815	COG0179	Fumarylacetoacetate (FAA) hydrolase
GAY71_RS05825	COG1404	Belongs to the peptidase S8 family
GAY71_RS05835	COG0367	asparagine synthase
GAY71_RS05840	COG2318	DinB family
GAY71_RS05845	COG1562	ergosterol biosynthetic process
GAY71_RS05850	COG0534	Mate efflux family protein
GAY71_RS05855	COG2207	Transcriptional regulator
GAY71_RS05855	COG1917	Cupin 2, conserved barrel domain protein
GAY71_RS05860	COG1609	Transcriptional regulator
GAY71_RS05865	COG0673	inositol 2-dehydrogenase activity
GAY71_RS05870	COG2318	DinB family
GAY71_RS05875	COG1279	arginine transmembrane transporter activity
GAY71_RS05880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GAY71_RS05885	COG1357	PFAM Pentapeptide repeats (8 copies)
GAY71_RS05890	COG2267	carboxylic ester hydrolase activity
GAY71_RS05895	COG0529	Catalyzes the synthesis of activated sulfate
GAY71_RS05900	COG2046	Belongs to the sulfate adenylyltransferase family
GAY71_RS05905	COG0175	sulfate reduction
GAY71_RS05910	COG2045	Belongs to the ComB family
GAY71_RS05915	COG1809	phosphosulfolactate synthase activity
GAY71_RS05920	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GAY71_RS05925	COG4948	Mandelate Racemase Muconate Lactonizing
GAY71_RS05930	COG2814	Major facilitator Superfamily
GAY71_RS05935	COG0454	-acetyltransferase
GAY71_RS05940	COG2153	protein acetylation
GAY71_RS05945	COG0646	methionine synthase
GAY71_RS05945	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GAY71_RS05950	COG1666	GTP binding
GAY71_RS05955	COG2996	Protein conserved in bacteria
GAY71_RS05975	COG1695	Transcriptional regulator
GAY71_RS05990	COG3227	Zinc metalloprotease (Elastase)
GAY71_RS05995	COG1307	EDD domain protein, DegV family
GAY71_RS06000	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GAY71_RS06015	COG0561	phosphatase activity
GAY71_RS06020	COG1073	alpha beta
GAY71_RS06025	COG2151	metal-sulfur cluster biosynthetic enzyme
GAY71_RS06035	COG0277	FAD linked oxidase domain protein
GAY71_RS06040	COG2271	Major facilitator Superfamily
GAY71_RS06045	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GAY71_RS06060	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GAY71_RS06065	COG0505	Belongs to the CarA family
GAY71_RS06070	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GAY71_RS06075	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GAY71_RS06090	COG2267	carboxylic ester hydrolase activity
GAY71_RS06100	COG1744	ABC transporter substrate-binding protein PnrA-like
GAY71_RS06115	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GAY71_RS06120	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GAY71_RS06125	COG5504	Zn-dependent protease
GAY71_RS06130	COG0444	Belongs to the ABC transporter superfamily
GAY71_RS06135	COG4608	Belongs to the ABC transporter superfamily
GAY71_RS06145	COG0601	transmembrane transport
GAY71_RS06150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GAY71_RS06160	COG0180	Tryptophanyl-tRNA synthetase
GAY71_RS06165	COG4166	transmembrane transport
GAY71_RS06170	COG0601	transmembrane transport
GAY71_RS06175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GAY71_RS06180	COG0444	Belongs to the ABC transporter superfamily
GAY71_RS06185	COG4608	Belongs to the ABC transporter superfamily
GAY71_RS06190	COG2814	Major facilitator Superfamily
GAY71_RS06195	COG0456	acetyltransferase
GAY71_RS06200	COG1393	Belongs to the ArsC family
GAY71_RS06205	COG0861	Integral membrane protein TerC family
GAY71_RS06215	COG4862	establishment of competence for transformation
GAY71_RS06225	COG4469	Competence protein
GAY71_RS06230	COG1164	Oligoendopeptidase f
GAY71_RS06245	COG2346	COG2346, Truncated hemoglobins
GAY71_RS06250	COG0741	lytic transglycosylase activity
GAY71_RS06255	COG4116	CYTH
GAY71_RS06265	COG2357	RelA SpoT domain protein
GAY71_RS06270	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GAY71_RS06275	COG0564	pseudouridine synthase activity
GAY71_RS06280	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GAY71_RS06285	COG0569	domain protein
GAY71_RS06285	COG0475	glutathione-regulated potassium exporter activity
GAY71_RS06290	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GAY71_RS06295	COG0352	thiamine-phosphate diphosphorylase activity
GAY71_RS06300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GAY71_RS06305	COG2104	thiamine diphosphate biosynthetic process
GAY71_RS06310	COG2022	thiamine diphosphate biosynthetic process
GAY71_RS06315	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GAY71_RS06320	COG0351	phosphomethylpyrimidine kinase
GAY71_RS06325	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GAY71_RS06380	COG0210	DNA helicase
GAY71_RS06390	COG2153	protein acetylation
GAY71_RS06395	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GAY71_RS06400	COG2382	esterase
GAY71_RS06405	COG0626	cystathionine gamma-synthase activity
GAY71_RS06410	COG0626	cystathionine gamma-synthase activity
GAY71_RS06415	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GAY71_RS06420	COG5505	Protein of unknown function (DUF819)
GAY71_RS06450	COG3677	Transposase
GAY71_RS06465	COG5484	DNA packaging
GAY71_RS06470	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GAY71_RS06475	COG1028	Short-chain dehydrogenase reductase Sdr
GAY71_RS06485	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GAY71_RS06485	COG3711	transcriptional antiterminator
GAY71_RS06490	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GAY71_RS06490	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GAY71_RS06490	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GAY71_RS06495	COG1482	cell wall glycoprotein biosynthetic process
GAY71_RS06505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GAY71_RS06515	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GAY71_RS06530	COG0109	protoheme IX farnesyltransferase activity
GAY71_RS06540	COG0726	polysaccharide deacetylase
GAY71_RS06555	COG5504	Zn-dependent protease
GAY71_RS06560	COG2205	protein histidine kinase activity
GAY71_RS06570	COG3383	formate dehydrogenase (NAD+) activity
GAY71_RS06575	COG2427	Protein of unknown function (DUF1641)
GAY71_RS06585	COG1051	belongs to the nudix hydrolase family
GAY71_RS06595	COG2124	cytochrome p450
GAY71_RS06600	COG1819	glycosyl
GAY71_RS06610	COG1587	Uroporphyrinogen-III synthase
GAY71_RS06615	COG0390	transport system, permease component
GAY71_RS06620	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GAY71_RS06625	COG0697	spore germination
GAY71_RS06630	COG4297	protein containing double-stranded beta helix domain
GAY71_RS06640	COG1252	NADH dehydrogenase
GAY71_RS06645	COG1904	glucuronate isomerase
GAY71_RS06650	COG2211	Major facilitator Superfamily
GAY71_RS06655	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GAY71_RS06660	COG1063	alcohol dehydrogenase
GAY71_RS06665	COG1312	Catalyzes the dehydration of D-mannonate
GAY71_RS06670	COG1028	Short-chain dehydrogenase reductase Sdr
GAY71_RS06675	COG2271	Major facilitator Superfamily
GAY71_RS06680	COG1609	Transcriptional regulator
GAY71_RS06685	COG0246	Mannitol dehydrogenase
GAY71_RS06690	COG2721	sulfolactate sulfo-lyase activity
GAY71_RS06695	COG0730	response to heat
GAY71_RS06700	COG2318	DinB family
GAY71_RS06705	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GAY71_RS06710	COG0457	Tetratricopeptide repeat
GAY71_RS06720	COG2350	Protein conserved in bacteria
GAY71_RS06725	COG5632	N-Acetylmuramoyl-L-alanine amidase
GAY71_RS06725	COG3409	Peptidoglycan-binding domain 1 protein
GAY71_RS06725	COG1388	LysM domain
GAY71_RS06735	COG4195	phage-related replication protein
GAY71_RS06740	COG3546	catalase activity
GAY71_RS06745	COG2856	Zn peptidase
GAY71_RS06750	COG1396	sequence-specific DNA binding
GAY71_RS06760	COG1522	sequence-specific DNA binding
GAY71_RS06765	COG1484	DNA-dependent DNA replication
GAY71_RS06785	COG1595	DNA-templated transcription, initiation
GAY71_RS06790	COG5484	DNA packaging
GAY71_RS06790	COG3728	DNA packaging
GAY71_RS06795	COG1783	phage Terminase large subunit
GAY71_RS06800	COG5518	Phage portal protein
GAY71_RS06805	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GAY71_RS06810	COG4653	Phage capsid family
GAY71_RS06860	COG3953	SLT domain
GAY71_RS06860	COG5412	phage tail tape measure protein
GAY71_RS06865	COG1652	LysM domain
GAY71_RS06870	COG4193	domain, Protein
GAY71_RS06880	COG3628	GPW Gp25 family protein
GAY71_RS06885	COG3299	homolog of phage Mu protein gp47
GAY71_RS06890	COG3778	Protein conserved in bacteria
GAY71_RS06930	COG3409	Peptidoglycan-binding domain 1 protein
GAY71_RS06930	COG5632	N-Acetylmuramoyl-L-alanine amidase
GAY71_RS06950	COG0306	phosphate transporter
GAY71_RS06955	COG1392	Phosphate transport regulator
GAY71_RS06960	COG0531	amino acid
GAY71_RS06965	COG0346	lactoylglutathione lyase activity
GAY71_RS06975	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GAY71_RS06980	COG0463	Glycosyl transferase, family 2
GAY71_RS06985	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GAY71_RS06990	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GAY71_RS06995	COG2362	D-Aminopeptidase
GAY71_RS07000	COG0601	transmembrane transport
GAY71_RS07005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GAY71_RS07010	COG0444	Belongs to the ABC transporter superfamily
GAY71_RS07015	COG4166	transmembrane transport
GAY71_RS07020	COG1619	proteins homologs of microcin C7 resistance protein MccF
GAY71_RS07025	COG4948	Mandelate Racemase Muconate Lactonizing
GAY71_RS07030	COG0791	NLP P60 protein
GAY71_RS07035	COG4608	Belongs to the ABC transporter superfamily
GAY71_RS07040	COG2706	6-phosphogluconolactonase activity
GAY71_RS07045	COG1834	amidinotransferase
GAY71_RS07050	COG1607	acyl-coa hydrolase
GAY71_RS07055	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GAY71_RS07055	COG1017	nitric oxide dioxygenase activity
GAY71_RS07065	COG2323	membrane
GAY71_RS07070	COG2318	DinB family
GAY71_RS07075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GAY71_RS07080	COG2076	Multidrug Resistance protein
GAY71_RS07085	COG2076	Multidrug Resistance protein
GAY71_RS07090	COG0788	formyltetrahydrofolate deformylase activity
GAY71_RS07095	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GAY71_RS07100	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GAY71_RS07105	COG1764	response to oxidative stress
GAY71_RS07110	COG1846	Transcriptional regulator
GAY71_RS07115	COG1764	response to oxidative stress
GAY71_RS07125	COG0590	tRNA wobble adenosine to inosine editing
GAY71_RS07130	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GAY71_RS07135	COG1404	Belongs to the peptidase S8 family
GAY71_RS07140	COG1366	Belongs to the anti-sigma-factor antagonist family
GAY71_RS07145	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GAY71_RS07150	COG1122	ATPase activity
GAY71_RS07155	COG4721	ABC-type cobalt transport system, permease component
GAY71_RS07165	COG0745	RESPONSE REGULATOR receiver
GAY71_RS07170	COG3850	Histidine kinase
GAY71_RS07170	COG5002	protein histidine kinase activity
GAY71_RS07175	COG3212	peptidase
GAY71_RS07180	COG3212	peptidase
GAY71_RS07190	COG2239	Acts as a magnesium transporter
GAY71_RS07195	COG0789	Transcriptional regulator
GAY71_RS07210	COG1846	Transcriptional regulator
GAY71_RS07215	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GAY71_RS07220	COG0726	polysaccharide deacetylase
GAY71_RS07225	COG1408	metallophosphoesterase
GAY71_RS07235	COG0463	Glycosyl transferase, family 2
GAY71_RS07240	COG1793	dna ligase
GAY71_RS07240	COG3285	dna ligase
GAY71_RS07245	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GAY71_RS07250	COG3300	MHYT domain
GAY71_RS07250	COG5001	Diguanylate cyclase
GAY71_RS07255	COG0586	Pfam SNARE associated Golgi protein
GAY71_RS07260	COG0861	Integral membrane protein TerC family
GAY71_RS07265	COG1191	sigma factor activity
GAY71_RS07285	COG0501	Belongs to the peptidase M48B family
GAY71_RS07290	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GAY71_RS07305	COG3594	Acyltransferase
GAY71_RS07310	COG5002	protein histidine kinase activity
GAY71_RS07315	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GAY71_RS07325	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GAY71_RS07330	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
GAY71_RS07335	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GAY71_RS07340	COG0436	Aminotransferase
GAY71_RS07345	COG1850	ribulose-bisphosphate carboxylase activity
GAY71_RS07350	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
GAY71_RS07355	COG0235	Class ii aldolase
GAY71_RS07360	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
GAY71_RS07365	COG3339	Conserved Protein
GAY71_RS07380	COG3852	Histidine kinase
GAY71_RS07385	COG1846	Transcriptional regulator
GAY71_RS07390	COG1360	Flagellar Motor Protein
GAY71_RS07395	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GAY71_RS07400	COG0542	response to heat
GAY71_RS07405	COG3949	Membrane
GAY71_RS07410	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GAY71_RS07415	COG0720	synthase
GAY71_RS07420	COG0602	queuosine metabolic process
GAY71_RS07425	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GAY71_RS07430	COG1733	regulation of RNA biosynthetic process
GAY71_RS07435	COG1028	Short-chain dehydrogenase reductase Sdr
GAY71_RS07440	COG4641	Protein conserved in bacteria
GAY71_RS07440	COG1388	LysM domain
GAY71_RS07445	COG1388	LysM domain
GAY71_RS07460	COG4873	Protein conserved in bacteria
GAY71_RS07470	COG3773	Cell wall hydrolase
GAY71_RS07475	COG2244	polysaccharide biosynthetic process
GAY71_RS07480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GAY71_RS07485	COG2217	Heavy metal translocating P-type atpase
GAY71_RS07495	COG0006	proline dipeptidase activity
GAY71_RS07500	COG1609	Transcriptional regulator
GAY71_RS07505	COG3711	transcriptional antiterminator
GAY71_RS07510	COG2190	(PTS) system
GAY71_RS07510	COG1263	PTS System
GAY71_RS07510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GAY71_RS07515	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GAY71_RS07520	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GAY71_RS07530	COG1533	DNA photolyase activity
GAY71_RS07535	COG0456	acetyltransferase
GAY71_RS07540	COG0840	transmembrane signaling receptor activity
GAY71_RS07545	COG2084	Dehydrogenase
GAY71_RS07550	COG2340	Cysteine-rich secretory protein family
GAY71_RS07555	COG0768	penicillin binding
GAY71_RS07560	COG4191	Histidine kinase
GAY71_RS07565	COG0436	Aminotransferase
GAY71_RS07575	COG0835	chemotaxis
GAY71_RS07575	COG0784	Response regulator, receiver
GAY71_RS07585	COG2814	Major facilitator Superfamily
GAY71_RS07590	COG1376	ErfK ybiS ycfS ynhG family protein
GAY71_RS07595	COG1408	metallophosphoesterase
GAY71_RS07600	COG1028	Short-chain dehydrogenase reductase Sdr
GAY71_RS07605	COG3409	Peptidoglycan-binding domain 1 protein
GAY71_RS07610	COG3409	Peptidoglycan-binding domain 1 protein
GAY71_RS07620	COG2200	EAL domain
GAY71_RS07630	COG4703	Protein of unknown function (DUF1797)
GAY71_RS07635	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
GAY71_RS07645	COG0517	IMP dehydrogenase activity
GAY71_RS07650	COG0583	DNA-binding transcription factor activity
GAY71_RS07655	COG0716	FMN binding
GAY71_RS07665	COG0716	FMN binding
GAY71_RS07670	COG2171	N-acyltransferase activity
GAY71_RS07675	COG1473	amidohydrolase
GAY71_RS07685	COG0668	transmembrane transport
GAY71_RS07690	COG0450	alkyl hydroperoxide reductase
GAY71_RS07695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GAY71_RS07710	COG0746	molybdenum cofactor guanylyltransferase activity
GAY71_RS07715	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GAY71_RS07720	COG0303	'Molybdopterin
GAY71_RS07725	COG1763	Mo-molybdopterin cofactor biosynthetic process
GAY71_RS07730	COG0314	molybdopterin synthase activity
GAY71_RS07735	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GAY71_RS07740	COG1132	(ABC) transporter
GAY71_RS07745	COG1132	(ABC) transporter
GAY71_RS07755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GAY71_RS07760	COG1136	(ABC) transporter
GAY71_RS07765	COG0577	efflux transmembrane transporter activity
GAY71_RS07770	COG1349	DNA-binding transcription factor activity
GAY71_RS07775	COG1105	Belongs to the carbohydrate kinase PfkB family
GAY71_RS07780	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GAY71_RS07780	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GAY71_RS07780	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GAY71_RS07785	COG0681	Belongs to the peptidase S26 family
GAY71_RS07795	COG0488	(ABC) transporter
GAY71_RS07800	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GAY71_RS07805	COG2309	aminopeptidase activity
GAY71_RS07815	COG1077	Cell shape determining protein MreB Mrl
GAY71_RS07820	COG2002	toxin-antitoxin pair type II binding
GAY71_RS07825	COG3852	Histidine kinase
GAY71_RS07830	COG2105	PFAM AIG2 family protein
GAY71_RS07830	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
GAY71_RS07835	COG0569	domain protein
GAY71_RS07840	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GAY71_RS07845	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GAY71_RS07855	COG0561	phosphatase activity
GAY71_RS07860	COG0242	peptide deformylase activity
GAY71_RS07870	COG0497	DNA recombination
GAY71_RS07875	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GAY71_RS07880	COG0022	dehydrogenase e1 component
GAY71_RS07885	COG0508	dehydrogenase complex catalyzes the overall conversion of
GAY71_RS07890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GAY71_RS07895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GAY71_RS07905	COG1982	Orn Lys Arg decarboxylase major
GAY71_RS07910	COG4476	Belongs to the UPF0223 family
GAY71_RS07915	COG4493	Belongs to the UPF0637 family
GAY71_RS07925	COG0483	inositol monophosphate 1-phosphatase activity
GAY71_RS07935	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GAY71_RS07955	COG1595	DNA-templated transcription, initiation
GAY71_RS07985	COG4896	Protein conserved in bacteria
GAY71_RS07995	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GAY71_RS08000	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GAY71_RS08005	COG2066	Belongs to the glutaminase family
GAY71_RS08010	COG4838	Belongs to the UPF0358 family
GAY71_RS08015	COG0772	Belongs to the SEDS family
GAY71_RS08020	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GAY71_RS08025	COG1612	heme a metabolic process
GAY71_RS08030	COG0109	protoheme IX farnesyltransferase activity
GAY71_RS08035	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GAY71_RS08035	COG2010	Cytochrome c
GAY71_RS08040	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GAY71_RS08045	COG1845	cytochrome c oxidase, subunit III
GAY71_RS08050	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GAY71_RS08055	COG3336	cytochrome c oxidase
GAY71_RS08065	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
GAY71_RS08070	COG2340	Cysteine-rich secretory protein family
GAY71_RS08085	COG3679	Belongs to the UPF0342 family
GAY71_RS08090	COG4471	UPF0298 protein
GAY71_RS08095	COG0742	ribosomal rna small subunit methyltransferase
GAY71_RS08100	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GAY71_RS08105	COG3314	Sporulation integral membrane protein YlbJ
GAY71_RS08110	COG1752	Esterase of the alpha-beta hydrolase superfamily
GAY71_RS08115	COG3480	Lon protease (S16) C-terminal proteolytic domain
GAY71_RS08120	COG1323	Belongs to the UPF0348 family
GAY71_RS08130	COG1399	metal-binding, possibly nucleic acid-binding protein
GAY71_RS08135	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GAY71_RS08145	COG0454	-acetyltransferase
GAY71_RS08150	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GAY71_RS08155	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
GAY71_RS08160	COG2001	Belongs to the MraZ family
GAY71_RS08165	COG0275	rRNA processing
GAY71_RS08170	COG4839	cell division protein FtsL
GAY71_RS08180	COG0768	penicillin binding
GAY71_RS08185	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GAY71_RS08190	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GAY71_RS08195	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GAY71_RS08200	COG0772	Belongs to the SEDS family
GAY71_RS08205	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GAY71_RS08210	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GAY71_RS08215	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GAY71_RS08220	COG3879	Bacterial protein of unknown function (DUF881)
GAY71_RS08225	COG3879	Bacterial protein of unknown function (DUF881)
GAY71_RS08230	COG3856	small basic protein
GAY71_RS08235	COG0849	cell division
GAY71_RS08240	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GAY71_RS08245	COG1404	Belongs to the peptidase S8 family
GAY71_RS08245	COG4412	M6 family metalloprotease domain protein
GAY71_RS08255	COG1191	sigma factor activity
GAY71_RS08260	COG1191	sigma factor activity
GAY71_RS08265	COG1119	ATPase activity
GAY71_RS08270	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GAY71_RS08275	COG1873	PFAM PRC-barrel domain
GAY71_RS08285	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GAY71_RS08290	COG1799	cell septum assembly
GAY71_RS08295	COG0762	integral membrane protein
GAY71_RS08300	COG2302	S4 RNA-binding domain
GAY71_RS08305	COG3599	regulation of cell shape
GAY71_RS08310	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GAY71_RS08315	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GAY71_RS08320	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GAY71_RS08325	COG0564	pseudouridine synthase activity
GAY71_RS08330	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GAY71_RS08335	COG2233	PERMEase
GAY71_RS08340	COG0540	Belongs to the ATCase OTCase family
GAY71_RS08345	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GAY71_RS08350	COG0505	Belongs to the CarA family
GAY71_RS08355	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GAY71_RS08360	COG0543	2 iron, 2 sulfur cluster binding
GAY71_RS08365	COG0167	dihydroorotate dehydrogenase activity
GAY71_RS08370	COG0284	orotidine-5'-phosphate decarboxylase activity
GAY71_RS08375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GAY71_RS08380	COG0175	sulfate reduction
GAY71_RS08385	COG0306	phosphate transporter
GAY71_RS08390	COG2046	Belongs to the sulfate adenylyltransferase family
GAY71_RS08395	COG0529	Catalyzes the synthesis of activated sulfate
GAY71_RS08400	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GAY71_RS08405	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
GAY71_RS08410	COG1648	precorrin-2 dehydrogenase activity
GAY71_RS08420	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GAY71_RS08425	COG1561	YicC-like family, N-terminal region
GAY71_RS08430	COG2052	Domain of unknown function (DUF370)
GAY71_RS08435	COG0194	GDP metabolic process
GAY71_RS08440	COG1758	RNA polymerase activity
GAY71_RS08445	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GAY71_RS08450	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GAY71_RS08455	COG0242	peptide deformylase activity
GAY71_RS08460	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GAY71_RS08465	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GAY71_RS08465	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GAY71_RS08470	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GAY71_RS08475	COG0631	protein serine/threonine phosphatase activity
GAY71_RS08480	COG2815	serine threonine protein kinase
GAY71_RS08480	COG0515	serine threonine protein kinase
GAY71_RS08485	COG1162	GTPase activity
GAY71_RS08495	COG1564	THIamine pyrophosphokinase
GAY71_RS08505	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GAY71_RS08510	COG1302	Protein conserved in bacteria
GAY71_RS08515	COG1461	Dihydroxyacetone kinase
GAY71_RS08520	COG1760	l-serine dehydratase
GAY71_RS08525	COG1760	l-serine dehydratase
GAY71_RS08530	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GAY71_RS08535	COG1349	DNA-binding transcription factor activity
GAY71_RS08535	COG2050	protein possibly involved in aromatic compounds catabolism
GAY71_RS08540	COG0416	fatty acid biosynthetic process
GAY71_RS08545	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GAY71_RS08550	COG1028	Short-chain dehydrogenase reductase Sdr
GAY71_RS08555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GAY71_RS08560	COG0571	ribonuclease III activity
GAY71_RS08565	COG1196	nuclear chromosome segregation
GAY71_RS08570	COG0552	protein localization to endoplasmic reticulum
GAY71_RS08580	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GAY71_RS08585	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GAY71_RS08590	COG0228	four-way junction DNA binding
GAY71_RS08595	COG1837	Belongs to the UPF0109 family
GAY71_RS08605	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GAY71_RS08610	COG0336	Belongs to the RNA methyltransferase TrmD family
GAY71_RS08615	COG0335	large ribosomal subunit rRNA binding
GAY71_RS08620	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GAY71_RS08625	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GAY71_RS08635	COG2257	FlhB HrpN YscU SpaS Family
GAY71_RS08640	COG0045	succinate-CoA ligase (ADP-forming) activity
GAY71_RS08645	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GAY71_RS08650	COG0758	DNA mediated transformation
GAY71_RS08655	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GAY71_RS08660	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GAY71_RS08665	COG4974	Belongs to the 'phage' integrase family
GAY71_RS08670	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GAY71_RS08675	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GAY71_RS08680	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GAY71_RS08685	COG1815	bacterial-type flagellum-dependent cell motility
GAY71_RS08690	COG1558	bacterial-type flagellum-dependent cell motility
GAY71_RS08695	COG1677	Flagellar hook-basal body complex protein FliE
GAY71_RS08700	COG1766	The M ring may be actively involved in energy transduction
GAY71_RS08705	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GAY71_RS08710	COG1317	bacterial-type flagellum organization
GAY71_RS08715	COG1157	protein secretion by the type III secretion system
GAY71_RS08720	COG2882	bacterial-type flagellum organization
GAY71_RS08725	COG3334	PFAM MgtE intracellular
GAY71_RS08730	COG3144	bacterial-type flagellum assembly
GAY71_RS08735	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GAY71_RS08740	COG4786	Flagellar basal body rod
GAY71_RS08745	COG1582	Flagellar protein (FlbD)
GAY71_RS08750	COG1580	Controls the rotational direction of flagella during chemotaxis
GAY71_RS08755	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GAY71_RS08760	COG1776	CheC inhibitor of MCP methylation
GAY71_RS08760	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GAY71_RS08765	COG2201	protein-glutamate methylesterase activity
GAY71_RS08770	COG3190	flagellar
GAY71_RS08775	COG1338	Plays a role in the flagellum-specific transport system
GAY71_RS08780	COG1987	bacterial-type flagellum assembly
GAY71_RS08785	COG1684	flagellar biosynthetic protein fliR
GAY71_RS08790	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GAY71_RS08795	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GAY71_RS08800	COG1419	protein localization to endoplasmic reticulum
GAY71_RS08805	COG0455	bacterial-type flagellum organization
GAY71_RS08810	COG2201	protein-glutamate methylesterase activity
GAY71_RS08815	COG0643	Histidine kinase
GAY71_RS08815	COG2198	Histidine kinase
GAY71_RS08820	COG0835	chemotaxis
GAY71_RS08825	COG1776	CheC inhibitor of MCP methylation
GAY71_RS08830	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GAY71_RS08835	COG1191	sigma factor activity
GAY71_RS08845	COG0052	Belongs to the universal ribosomal protein uS2 family
GAY71_RS08850	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GAY71_RS08855	COG0528	UMP kinase activity
GAY71_RS08860	COG0233	cytoplasmic translational termination
GAY71_RS08865	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GAY71_RS08870	COG4589	Belongs to the CDS family
GAY71_RS08875	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GAY71_RS08880	COG0750	zinc metalloprotease
GAY71_RS08885	COG0442	prolyl-tRNA aminoacylation
GAY71_RS08890	COG2176	DNA-directed DNA polymerase activity
GAY71_RS08895	COG0779	Required for maturation of 30S ribosomal subunits
GAY71_RS08900	COG0195	Participates in both transcription termination and antitermination
GAY71_RS08905	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GAY71_RS08910	COG1358	cellular component organization or biogenesis
GAY71_RS08915	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GAY71_RS08920	COG1550	Protein conserved in bacteria
GAY71_RS08925	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GAY71_RS08930	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GAY71_RS08935	COG0196	riboflavin kinase activity
GAY71_RS08940	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GAY71_RS08945	COG1185	polyribonucleotide nucleotidyltransferase activity
GAY71_RS08950	COG0726	polysaccharide deacetylase
GAY71_RS08955	COG0612	Peptidase, M16
GAY71_RS08960	COG1873	PFAM PRC-barrel domain
GAY71_RS08965	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GAY71_RS08970	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GAY71_RS08975	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GAY71_RS08980	COG0527	aspartate kinase activity
GAY71_RS08985	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GAY71_RS08990	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GAY71_RS08995	COG0740	serine-type endopeptidase activity
GAY71_RS09005	COG1674	ftsk spoiiie
GAY71_RS09005	COG4980	gas vesicle protein
GAY71_RS09010	COG2188	Transcriptional regulator
GAY71_RS09015	COG2814	Major facilitator Superfamily
GAY71_RS09020	COG0612	Peptidase, M16
GAY71_RS09025	COG0612	Peptidase, M16
GAY71_RS09030	COG0300	oxidoreductase activity
GAY71_RS09045	COG1426	Protein conserved in bacteria
GAY71_RS09050	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GAY71_RS09055	COG1058	Belongs to the CinA family
GAY71_RS09055	COG1546	Belongs to the CinA family
GAY71_RS09075	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GAY71_RS09080	COG1418	mRNA catabolic process
GAY71_RS09085	COG1692	metallophosphoesterase
GAY71_RS09090	COG2359	stage V sporulation protein S
GAY71_RS09095	COG1063	alcohol dehydrogenase
GAY71_RS09100	COG0156	8-amino-7-oxononanoate synthase activity
GAY71_RS09105	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GAY71_RS09110	COG4550	Control of competence regulator ComK, YlbF/YmcA
GAY71_RS09120	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GAY71_RS09125	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GAY71_RS09140	COG3226	Transcriptional regulator
GAY71_RS09145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GAY71_RS09155	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GAY71_RS09160	COG3321	synthase
GAY71_RS09165	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GAY71_RS09165	COG2070	2-Nitropropane dioxygenase
GAY71_RS09170	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GAY71_RS09175	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GAY71_RS09180	COG3425	synthase
GAY71_RS09185	COG1024	Enoyl-CoA hydratase
GAY71_RS09190	COG1024	Enoyl-CoA hydratase
GAY71_RS09195	COG0300	oxidoreductase activity
GAY71_RS09195	COG0318	PFAM AMP-dependent synthetase and ligase
GAY71_RS09195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GAY71_RS09195	COG1028	Short-chain dehydrogenase reductase Sdr
GAY71_RS09195	COG3321	synthase
GAY71_RS09200	COG3321	synthase
GAY71_RS09200	COG0300	oxidoreductase activity
GAY71_RS09200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GAY71_RS09200	COG4221	oxidoreductase activity
GAY71_RS09205	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GAY71_RS09205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GAY71_RS09205	COG1028	Short-chain dehydrogenase reductase Sdr
GAY71_RS09205	COG3321	synthase
GAY71_RS09205	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GAY71_RS09210	COG3321	synthase
GAY71_RS09210	COG4221	oxidoreductase activity
GAY71_RS09210	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GAY71_RS09210	COG1028	Short-chain dehydrogenase reductase Sdr
GAY71_RS09215	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GAY71_RS09215	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GAY71_RS09215	COG3321	synthase
GAY71_RS09215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GAY71_RS09220	COG2124	cytochrome p450
GAY71_RS09230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GAY71_RS09235	COG1404	Belongs to the peptidase S8 family
GAY71_RS09240	COG4195	phage-related replication protein
GAY71_RS09245	COG1764	response to oxidative stress
GAY71_RS09250	COG2076	Multidrug Resistance protein
GAY71_RS09255	COG2076	Multidrug Resistance protein
GAY71_RS09270	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GAY71_RS09275	COG1923	regulation of RNA biosynthetic process
GAY71_RS09290	COG1780	Probably involved in ribonucleotide reductase function
GAY71_RS09295	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GAY71_RS09300	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GAY71_RS09305	COG4112	unkown
GAY71_RS09310	COG0860	N-Acetylmuramoyl-L-alanine amidase
GAY71_RS09315	COG0464	growth
GAY71_RS09320	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GAY71_RS09325	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
GAY71_RS09330	COG0789	Transcriptional regulator
GAY71_RS09335	COG0174	glutamine synthetase
GAY71_RS09355	COG4282	regulation of fungal-type cell wall biogenesis
GAY71_RS09365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GAY71_RS09395	COG0135	phosphoribosylanthranilate isomerase activity
GAY71_RS09400	COG2211	Major facilitator Superfamily
GAY71_RS09405	COG3507	Belongs to the glycosyl hydrolase 43 family
GAY71_RS09410	COG1940	carbohydrate kinase activity
GAY71_RS09415	COG2115	Belongs to the xylose isomerase family
GAY71_RS09420	COG1070	Carbohydrate kinase
GAY71_RS09430	COG1525	nuclease
GAY71_RS09435	COG2814	Major facilitator Superfamily
GAY71_RS09440	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GAY71_RS09450	COG0756	dUTP diphosphatase activity
GAY71_RS09465	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GAY71_RS09490	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GAY71_RS09505	COG3832	glyoxalase III activity
GAY71_RS09515	COG0697	spore germination
GAY71_RS09520	COG0531	amino acid
GAY71_RS09550	COG4195	phage-related replication protein
GAY71_RS09560	COG0346	lactoylglutathione lyase activity
GAY71_RS09565	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GAY71_RS09570	COG1388	LysM domain
GAY71_RS09575	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GAY71_RS09580	COG4224	UPF0291 protein
GAY71_RS09585	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GAY71_RS09595	COG3763	UPF0154 protein
GAY71_RS09605	COG0785	Cytochrome C biogenesis protein
GAY71_RS09610	COG2201	protein-glutamate methylesterase activity
GAY71_RS09615	COG4846	Membrane protein involved in cytochrome C biogenesis
GAY71_RS09625	COG0071	Belongs to the small heat shock protein (HSP20) family
GAY71_RS09640	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GAY71_RS09645	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GAY71_RS09665	COG0824	Thioesterase
GAY71_RS09675	COG4841	protein insertion into membrane
GAY71_RS09680	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GAY71_RS09685	COG1832	CoA-binding protein
GAY71_RS09690	COG0187	DNA topoisomerase II activity
GAY71_RS09695	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GAY71_RS09705	COG1115	amino acid carrier protein
GAY71_RS09710	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
GAY71_RS09720	COG5520	Belongs to the glycosyl hydrolase 30 family
GAY71_RS09725	COG3507	Belongs to the glycosyl hydrolase 43 family
GAY71_RS09730	COG2246	polysaccharide biosynthetic process
GAY71_RS09735	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GAY71_RS09740	COG0586	Pfam SNARE associated Golgi protein
GAY71_RS09745	COG2404	hydrolase activity, acting on ester bonds
GAY71_RS09750	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GAY71_RS09755	COG1024	Enoyl-CoA hydratase
GAY71_RS09760	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GAY71_RS09765	COG0511	ligase activity, forming carbon-carbon bonds
GAY71_RS09770	COG0439	Biotin carboxylase
GAY71_RS09775	COG0318	PFAM AMP-dependent synthetase and ligase
GAY71_RS09780	COG1960	acyl-CoA dehydrogenase activity
GAY71_RS09795	COG1649	PFAM Uncharacterised BCR, COG1649
GAY71_RS09805	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GAY71_RS09805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GAY71_RS09810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GAY71_RS09815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GAY71_RS09820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GAY71_RS09825	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GAY71_RS09830	COG2027	D-alanyl-D-alanine carboxypeptidase
GAY71_RS09835	COG2017	converts alpha-aldose to the beta-anomer
GAY71_RS09840	COG0534	Mate efflux family protein
GAY71_RS09855	COG0582	viral genome integration into host DNA
GAY71_RS09860	COG0166	Belongs to the GPI family
GAY71_RS09865	COG0405	Gamma-glutamyltransferase
GAY71_RS09870	COG0583	DNA-binding transcription factor activity
GAY71_RS09875	COG0604	alcohol dehydrogenase
GAY71_RS09880	COG0493	'glutamate synthase
GAY71_RS09885	COG0069	glutamate synthase activity
GAY71_RS09885	COG0070	glutamate synthase
GAY71_RS09885	COG0067	glutamate synthase
GAY71_RS09890	COG0583	DNA-binding transcription factor activity
GAY71_RS09895	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GAY71_RS09900	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GAY71_RS09910	COG0300	oxidoreductase activity
GAY71_RS09915	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GAY71_RS09925	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GAY71_RS09930	COG2814	Major facilitator Superfamily
GAY71_RS09935	COG1070	Carbohydrate kinase
GAY71_RS09940	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GAY71_RS09945	COG0243	molybdopterin cofactor binding
GAY71_RS09975	COG0840	transmembrane signaling receptor activity
GAY71_RS09975	COG5278	phosphoserine phosphatase activity
GAY71_RS09980	COG2368	4-hydroxyphenylacetate
GAY71_RS09985	COG4305	rare lipoprotein A
GAY71_RS09990	COG3619	membrane
GAY71_RS09995	COG3866	Pectate lyase
GAY71_RS10000	COG2135	peptidase activity
GAY71_RS10010	COG2140	Oxalate decarboxylase
GAY71_RS10025	COG0456	acetyltransferase
GAY71_RS10045	COG2720	vancomycin resistance protein
GAY71_RS10055	COG3655	Transcriptional regulator
GAY71_RS10060	COG3739	integral membrane protein
GAY71_RS10065	COG0583	DNA-binding transcription factor activity
GAY71_RS10070	COG0697	spore germination
GAY71_RS10080	COG0693	protein deglycase activity
GAY71_RS10085	COG2367	Beta-lactamase
GAY71_RS10110	COG0574	Belongs to the PEP-utilizing enzyme family
GAY71_RS10110	COG3848	Pyruvate phosphate dikinase
GAY71_RS10115	COG0726	polysaccharide deacetylase
GAY71_RS10120	COG2314	TM2 domain
GAY71_RS10125	COG1396	sequence-specific DNA binding
GAY71_RS10140	COG2135	peptidase activity
GAY71_RS10175	COG0457	Tetratricopeptide repeat
GAY71_RS10200	COG5290	Psort location Cytoplasmic, score
GAY71_RS10225	COG5444	nuclease activity
GAY71_RS10230	COG4282	regulation of fungal-type cell wall biogenesis
GAY71_RS10235	COG1231	oxidoreductase activity
GAY71_RS10240	COG5434	Belongs to the glycosyl hydrolase 28 family
GAY71_RS10245	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GAY71_RS10250	COG0662	Cupin 2, conserved barrel domain protein
GAY71_RS10250	COG2207	Transcriptional regulator
GAY71_RS10255	COG0456	acetyltransferase
GAY71_RS10260	COG1309	transcriptional regulator
GAY71_RS10265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GAY71_RS10270	COG3708	Transcriptional regulator
GAY71_RS10275	COG2378	regulation of single-species biofilm formation
GAY71_RS10285	COG0640	Transcriptional regulator
GAY71_RS10290	COG0741	lytic transglycosylase activity
GAY71_RS10295	COG2322	membrane
GAY71_RS10310	COG1619	proteins homologs of microcin C7 resistance protein MccF
GAY71_RS10315	COG3239	Fatty acid desaturase
GAY71_RS10320	COG4585	Histidine kinase
GAY71_RS10325	COG2197	response regulator
GAY71_RS10330	COG1388	LysM domain
GAY71_RS10330	COG3584	3D domain protein
GAY71_RS10335	COG0514	ATP-dependent DNA helicase (RecQ)
GAY71_RS10345	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GAY71_RS10350	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GAY71_RS10365	COG0071	Belongs to the small heat shock protein (HSP20) family
GAY71_RS10390	COG1012	belongs to the aldehyde dehydrogenase family
GAY71_RS10395	COG1657	PFAM Prenyltransferase squalene oxidase
GAY71_RS10400	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GAY71_RS10405	COG0733	neurotransmitter:sodium symporter activity
GAY71_RS10410	COG0385	Bile acid
GAY71_RS10415	COG0508	dehydrogenase complex catalyzes the overall conversion of
GAY71_RS10420	COG0567	Dehydrogenase, E1 component
GAY71_RS10425	COG4548	von Willebrand factor, type A
GAY71_RS10430	COG0714	Associated with various cellular activities
GAY71_RS10435	COG2032	superoxide dismutase activity
GAY71_RS10440	COG1388	LysM domain
GAY71_RS10440	COG0791	NLP P60 protein
GAY71_RS10445	COG1819	glycosyl
GAY71_RS10450	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GAY71_RS10455	COG0534	Mate efflux family protein
GAY71_RS10460	COG1366	Belongs to the anti-sigma-factor antagonist family
GAY71_RS10465	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GAY71_RS10470	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GAY71_RS10480	COG2962	Rard protein
GAY71_RS10495	COG2610	gluconate transmembrane transporter activity
GAY71_RS10500	COG1942	4-Oxalocrotonate Tautomerase
GAY71_RS10505	COG1733	regulation of RNA biosynthetic process
GAY71_RS10510	COG0778	Nitroreductase
GAY71_RS10515	COG0400	carboxylic ester hydrolase activity
GAY71_RS10520	COG0346	lactoylglutathione lyase activity
GAY71_RS10530	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GAY71_RS10535	COG3409	Peptidoglycan-binding domain 1 protein
GAY71_RS10535	COG0793	Belongs to the peptidase S41A family
GAY71_RS10540	COG2226	methyltransferase
GAY71_RS10550	COG1876	peptidase activity
GAY71_RS10555	COG0813	purine-nucleoside phosphorylase activity
GAY71_RS10570	COG0671	phosphoesterase, PA-phosphatase related
GAY71_RS10590	COG4479	Belongs to the UPF0346 family
GAY71_RS10600	COG1509	lysine 2,3-aminomutase activity
GAY71_RS10605	COG0456	acetyltransferase
GAY71_RS10610	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GAY71_RS10615	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GAY71_RS10620	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GAY71_RS10625	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GAY71_RS10640	COG0456	acetyltransferase
GAY71_RS10645	COG0463	Glycosyl transferase, family 2
GAY71_RS10660	COG4641	Protein conserved in bacteria
GAY71_RS10665	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
GAY71_RS10670	COG1086	Polysaccharide biosynthesis protein
GAY71_RS10680	COG3331	DNA recombination
GAY71_RS10735	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GAY71_RS10770	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
GAY71_RS10775	COG0756	dUTP diphosphatase activity
GAY71_RS10780	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GAY71_RS10800	COG1372	Participates in initiation and elongation during chromosome replication
GAY71_RS10800	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GAY71_RS10805	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GAY71_RS10805	COG1372	Participates in initiation and elongation during chromosome replication
GAY71_RS10810	COG1780	Probably involved in ribonucleotide reductase function
GAY71_RS10900	COG0270	DNA (cytosine-5-)-methyltransferase activity
GAY71_RS10910	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
GAY71_RS10915	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GAY71_RS10940	COG3584	3D domain protein
GAY71_RS10945	COG0587	DNA-directed DNA polymerase activity
GAY71_RS10950	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GAY71_RS10955	COG0358	DNA primase activity
GAY71_RS10960	COG0305	Participates in initiation and elongation during chromosome replication
GAY71_RS10970	COG2887	Belongs to the helicase family. UvrD subfamily
GAY71_RS11000	COG5434	Belongs to the glycosyl hydrolase 28 family
GAY71_RS11000	COG3420	alginic acid biosynthetic process
GAY71_RS11005	COG4195	phage-related replication protein
GAY71_RS11020	COG2135	peptidase activity
GAY71_RS11025	COG1793	dna ligase
GAY71_RS11080	COG4474	Belongs to the UPF0398 family
GAY71_RS11090	COG1388	LysM domain
GAY71_RS11110	COG3646	Phage regulatory protein
GAY71_RS11110	COG3645	SOS response
GAY71_RS11165	COG3655	Transcriptional regulator
GAY71_RS11180	COG0582	viral genome integration into host DNA
GAY71_RS11260	COG3655	Transcriptional regulator
GAY71_RS11300	COG1395	domain, Protein
GAY71_RS11315	COG0776	regulation of translation
GAY71_RS11350	COG4373	Mu-like prophage FluMu protein gp28
GAY71_RS11450	COG0582	viral genome integration into host DNA
GAY71_RS11480	COG1196	nuclear chromosome segregation
GAY71_RS11480	COG0741	lytic transglycosylase activity
GAY71_RS11480	COG0739	heme binding
GAY71_RS11490	COG2433	Pfam Transposase IS66
GAY71_RS11500	COG5434	Belongs to the glycosyl hydrolase 28 family
GAY71_RS11500	COG4632	Exopolysaccharide biosynthesis protein
GAY71_RS11515	COG5632	N-Acetylmuramoyl-L-alanine amidase
GAY71_RS11530	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GAY71_RS11535	COG0463	Glycosyl transferase, family 2
GAY71_RS11540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GAY71_RS11545	COG2274	protein secretion by the type I secretion system
GAY71_RS11545	COG3271	cysteine-type peptidase activity
GAY71_RS11560	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GAY71_RS11590	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GAY71_RS11605	COG5444	nuclease activity
GAY71_RS11610	COG4282	regulation of fungal-type cell wall biogenesis
GAY71_RS11625	COG1525	nuclease
GAY71_RS11635	COG2746	aminoglycoside 3-N-acetyltransferase activity
GAY71_RS11660	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GAY71_RS11665	COG1086	Polysaccharide biosynthesis protein
GAY71_RS11670	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GAY71_RS11675	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GAY71_RS11680	COG1846	Transcriptional regulator
GAY71_RS11685	COG0534	Mate efflux family protein
GAY71_RS11695	COG4698	Protein conserved in bacteria
GAY71_RS11700	COG2755	lipolytic protein G-D-S-L family
GAY71_RS11705	COG1999	signal sequence binding
GAY71_RS11715	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GAY71_RS11720	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GAY71_RS11725	COG1272	protein, Hemolysin III
GAY71_RS11730	COG0204	Acyl-transferase
GAY71_RS11735	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GAY71_RS11740	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GAY71_RS11745	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GAY71_RS11755	COG2136	Putative SAM-dependent methyltransferase
GAY71_RS11755	COG2521	methyltransferase
GAY71_RS11765	COG0129	dihydroxy-acid dehydratase activity
GAY71_RS11770	COG1413	lyase activity
GAY71_RS11775	COG1418	mRNA catabolic process
GAY71_RS11780	COG0386	Belongs to the glutathione peroxidase family
GAY71_RS11785	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GAY71_RS11790	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GAY71_RS11800	COG1278	Cold shock
GAY71_RS11820	COG0328	RNA-DNA hybrid ribonuclease activity
GAY71_RS11825	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GAY71_RS11830	COG0328	RNA-DNA hybrid ribonuclease activity
GAY71_RS11840	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GAY71_RS11855	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GAY71_RS11865	COG1755	Isoprenylcysteine carboxyl methyltransferase
GAY71_RS11870	COG3424	synthase
GAY71_RS11875	COG2233	PERMEase
GAY71_RS11880	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GAY71_RS11885	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GAY71_RS11895	COG0800	Aldolase
GAY71_RS11900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GAY71_RS11905	COG1609	Transcriptional regulator
GAY71_RS11910	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
GAY71_RS11915	COG1028	Short-chain dehydrogenase reductase Sdr
GAY71_RS11920	COG1199	ATP-dependent helicase activity
GAY71_RS11935	COG0116	Belongs to the methyltransferase superfamily
GAY71_RS11950	COG4474	Belongs to the UPF0398 family
GAY71_RS11965	COG3359	exonuclease
GAY71_RS11970	COG1111	helicase
GAY71_RS11970	COG1205	dead DEAH box helicase
GAY71_RS11975	COG2190	(PTS) system
GAY71_RS11980	COG0071	Belongs to the small heat shock protein (HSP20) family
GAY71_RS12015	COG3331	DNA recombination
GAY71_RS12020	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GAY71_RS12020	COG4499	WXG100 protein secretion system (Wss), protein YukC
GAY71_RS12030	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GAY71_RS12035	COG3935	DnaD domain protein
GAY71_RS12040	COG0017	Asparaginyl-tRNA synthetase
GAY71_RS12045	COG0436	Aminotransferase
GAY71_RS12050	COG5353	protein conserved in bacteria
GAY71_RS12060	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GAY71_RS12060	COG1199	ATP-dependent helicase activity
GAY71_RS12065	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GAY71_RS12070	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GAY71_RS12075	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GAY71_RS12080	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GAY71_RS12080	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GAY71_RS12085	COG0617	tRNA 3'-terminal CCA addition
GAY71_RS12090	COG0438	transferase activity, transferring glycosyl groups
GAY71_RS12095	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GAY71_RS12100	COG1803	Methylglyoxal synthase
GAY71_RS12105	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GAY71_RS12110	COG1694	Mazg nucleotide pyrophosphohydrolase
GAY71_RS12115	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GAY71_RS12125	COG4347	Protein of unknown function (DUF1405)
GAY71_RS12130	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GAY71_RS12130	COG2010	Cytochrome c
GAY71_RS12135	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GAY71_RS12140	COG0723	plastoquinol--plastocyanin reductase activity
GAY71_RS12150	COG5582	Belongs to the UPF0302 family
GAY71_RS12155	COG0457	Tetratricopeptide repeat
GAY71_RS12160	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GAY71_RS12165	COG0287	Prephenate dehydrogenase
GAY71_RS12170	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GAY71_RS12175	COG0159	tryptophan synthase activity
GAY71_RS12180	COG0133	tryptophan synthase activity
GAY71_RS12185	COG0135	phosphoribosylanthranilate isomerase activity
GAY71_RS12195	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GAY71_RS12200	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GAY71_RS12205	COG4401	Chorismate mutase type I
GAY71_RS12210	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GAY71_RS12215	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GAY71_RS12220	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GAY71_RS12225	COG0105	UTP biosynthetic process
GAY71_RS12230	COG0142	geranyltranstransferase activity
GAY71_RS12235	COG2226	methyltransferase
GAY71_RS12240	COG0142	geranyltranstransferase activity
GAY71_RS12250	COG0302	gtp cyclohydrolase
GAY71_RS12255	COG0776	regulation of translation
GAY71_RS12260	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GAY71_RS12275	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GAY71_RS12280	COG1160	GTP binding
GAY71_RS12305	COG1304	FMN binding
GAY71_RS12310	COG0539	negative regulation of cytoplasmic translation
GAY71_RS12315	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GAY71_RS12325	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
GAY71_RS12330	COG2959	enzyme of heme biosynthesis
GAY71_RS12335	COG3409	Peptidoglycan-binding domain 1 protein
GAY71_RS12335	COG3773	Cell wall hydrolase
GAY71_RS12340	COG2339	peptidase activity
GAY71_RS12345	COG0492	ferredoxin-NADP+ reductase activity
GAY71_RS12350	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GAY71_RS12355	COG4862	establishment of competence for transformation
GAY71_RS12360	COG1408	metallophosphoesterase
GAY71_RS12370	COG1388	LysM domain
GAY71_RS12375	COG1266	CAAX protease self-immunity
GAY71_RS12380	COG0514	ATP-dependent DNA helicase (RecQ)
GAY71_RS12385	COG4955	Helix-turn-helix domain
GAY71_RS12390	COG1141	Ferredoxin
GAY71_RS12395	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GAY71_RS12400	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GAY71_RS12405	COG0710	3-dehydroquinate dehydratase activity
GAY71_RS12415	COG1595	DNA-templated transcription, initiation
GAY71_RS12420	COG5002	protein histidine kinase activity
GAY71_RS12425	COG0745	RESPONSE REGULATOR receiver
GAY71_RS12430	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GAY71_RS12435	COG1333	cytochrome c biogenesis protein
GAY71_RS12440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GAY71_RS12445	COG1187	pseudouridine synthase activity
GAY71_RS12450	COG0700	Nucleoside recognition
GAY71_RS12455	COG2715	membrane protein required for spore maturation
GAY71_RS12460	COG1686	Belongs to the peptidase S11 family
GAY71_RS12470	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GAY71_RS12475	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GAY71_RS12485	COG1547	Domain of unknown function (DUF309)
GAY71_RS12495	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GAY71_RS12500	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GAY71_RS12500	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GAY71_RS12505	COG0307	riboflavin synthase, alpha
GAY71_RS12510	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GAY71_RS12510	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GAY71_RS12550	COG0307	riboflavin synthase, alpha
GAY71_RS12555	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GAY71_RS12555	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GAY71_RS12595	COG0307	riboflavin synthase, alpha
GAY71_RS12600	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GAY71_RS12600	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GAY71_RS12640	COG0307	riboflavin synthase, alpha
GAY71_RS12645	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GAY71_RS12645	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GAY71_RS12695	COG1547	Domain of unknown function (DUF309)
GAY71_RS12705	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GAY71_RS12710	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GAY71_RS12710	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GAY71_RS12715	COG0307	riboflavin synthase, alpha
GAY71_RS12720	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GAY71_RS12720	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GAY71_RS12760	COG0307	riboflavin synthase, alpha
GAY71_RS12765	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GAY71_RS12765	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GAY71_RS12810	COG1547	Domain of unknown function (DUF309)
GAY71_RS12815	COG0456	acetyltransferase
GAY71_RS12820	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GAY71_RS12825	COG0019	diaminopimelate decarboxylase activity
GAY71_RS12830	COG0697	spore germination
GAY71_RS12845	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GAY71_RS12865	COG1191	sigma factor activity
GAY71_RS12870	COG2172	sigma factor antagonist activity
GAY71_RS12875	COG1366	Belongs to the anti-sigma-factor antagonist family
GAY71_RS12880	COG1686	Belongs to the peptidase S11 family
GAY71_RS12885	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GAY71_RS12890	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GAY71_RS12895	COG4974	Belongs to the 'phage' integrase family
GAY71_RS12905	COG0735	belongs to the Fur family
GAY71_RS12910	COG1300	Membrane
GAY71_RS12920	COG0281	malic enzyme
GAY71_RS12925	COG1757	Na H antiporter
GAY71_RS12930	COG1027	Aspartate ammonia-lyase
GAY71_RS12935	COG0252	asparaginase activity
GAY71_RS12940	COG1396	sequence-specific DNA binding
GAY71_RS12945	COG1379	DNA repair
GAY71_RS12950	COG0494	nUDIX hydrolase
GAY71_RS12960	COG0667	Aldo Keto reductase
GAY71_RS12970	COG1073	alpha beta
GAY71_RS12980	COG4918	Iron-sulphur cluster biosynthesis
GAY71_RS12985	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GAY71_RS12985	COG0456	acetyltransferase
GAY71_RS12990	COG2329	Antibiotic biosynthesis monooxygenase
GAY71_RS12995	COG0456	acetyltransferase
GAY71_RS13005	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GAY71_RS13015	COG2211	Major facilitator Superfamily
GAY71_RS13020	COG0346	lactoylglutathione lyase activity
GAY71_RS13025	COG1072	(Pantothenic acid kinase))
GAY71_RS13030	COG3048	D-serine ammonia-lyase activity
GAY71_RS13035	COG0300	oxidoreductase activity
GAY71_RS13040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GAY71_RS13045	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GAY71_RS13050	COG4187	Peptidase family M20/M25/M40
GAY71_RS13055	COG1902	pentaerythritol trinitrate reductase activity
GAY71_RS13060	COG0596	Alpha beta hydrolase
GAY71_RS13070	COG1234	tRNA 3'-trailer cleavage
GAY71_RS13075	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GAY71_RS13080	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GAY71_RS13085	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GAY71_RS13095	COG0706	membrane insertase activity
GAY71_RS13100	COG3361	conserved protein (COG2071)
GAY71_RS13105	COG2195	Cleaves the N-terminal amino acid of tripeptides
GAY71_RS13110	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GAY71_RS13115	COG0346	lactoylglutathione lyase activity
GAY71_RS13125	COG1376	ErfK ybiS ycfS ynhG family protein
GAY71_RS13130	COG4129	membrane
GAY71_RS13135	COG1126	abc transporter atp-binding protein
GAY71_RS13140	COG0765	amino acid transport
GAY71_RS13145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GAY71_RS13155	COG1597	lipid kinase activity
GAY71_RS13160	COG2814	Major facilitator Superfamily
GAY71_RS13165	COG0789	Transcriptional regulator
GAY71_RS13165	COG4978	Transcriptional regulator
GAY71_RS13170	COG0508	dehydrogenase complex catalyzes the overall conversion of
GAY71_RS13175	COG0022	dehydrogenase e1 component
GAY71_RS13180	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GAY71_RS13185	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GAY71_RS13190	COG3426	butyrate kinase activity
GAY71_RS13195	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GAY71_RS13200	COG0280	phosphate acetyltransferase
GAY71_RS13205	COG3290	protein histidine kinase activity
GAY71_RS13205	COG3829	transcription factor binding
GAY71_RS13215	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GAY71_RS13220	COG2079	MmgE PrpD family protein
GAY71_RS13225	COG0372	Belongs to the citrate synthase family
GAY71_RS13230	COG1960	acyl-CoA dehydrogenase activity
GAY71_RS13235	COG1250	3-hydroxyacyl-CoA dehydrogenase
GAY71_RS13240	COG0183	Belongs to the thiolase family
GAY71_RS13245	COG0584	glycerophosphoryl diester phosphodiesterase
GAY71_RS13250	COG0860	N-Acetylmuramoyl-L-alanine amidase
GAY71_RS13265	COG1902	pentaerythritol trinitrate reductase activity
GAY71_RS13270	COG0745	RESPONSE REGULATOR receiver
GAY71_RS13275	COG0750	zinc metalloprotease
GAY71_RS13280	COG0497	DNA recombination
GAY71_RS13285	COG1438	arginine binding
GAY71_RS13290	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GAY71_RS13295	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GAY71_RS13300	COG0142	geranyltranstransferase activity
GAY71_RS13305	COG1722	exodeoxyribonuclease VII activity
GAY71_RS13310	COG1570	exodeoxyribonuclease VII activity
GAY71_RS13315	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GAY71_RS13320	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GAY71_RS13325	COG1302	Protein conserved in bacteria
GAY71_RS13330	COG0439	Biotin carboxylase
GAY71_RS13335	COG0511	ligase activity, forming carbon-carbon bonds
GAY71_RS13375	COG3854	ATPases associated with a variety of cellular activities
GAY71_RS13385	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GAY71_RS13390	COG0006	proline dipeptidase activity
GAY71_RS13395	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GAY71_RS13405	COG3872	metal-dependent enzyme
GAY71_RS13415	COG1752	Esterase of the alpha-beta hydrolase superfamily
GAY71_RS13420	COG1321	iron dependent repressor
GAY71_RS13425	COG0095	Lipoate-protein ligase
GAY71_RS13430	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GAY71_RS13435	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GAY71_RS13440	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GAY71_RS13445	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GAY71_RS13450	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GAY71_RS13465	COG1396	sequence-specific DNA binding
GAY71_RS13475	COG0681	Belongs to the peptidase S26 family
GAY71_RS13500	COG4940	Competence protein ComGF
GAY71_RS13510	COG4970	Tfp pilus assembly protein FimT
GAY71_RS13515	COG4537	Required for transformation and DNA binding
GAY71_RS13520	COG1459	type II secretion system
GAY71_RS13525	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GAY71_RS13530	COG0598	Magnesium transport protein CorA
GAY71_RS13535	COG1253	flavin adenine dinucleotide binding
GAY71_RS13540	COG1366	Belongs to the anti-sigma-factor antagonist family
GAY71_RS13550	COG1393	Belongs to the ArsC family
GAY71_RS13560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GAY71_RS13570	COG0011	TIGRFAM Protein of
GAY71_RS13580	COG2866	Carboxypeptidase
GAY71_RS13585	COG1368	sulfuric ester hydrolase activity
GAY71_RS13590	COG1940	carbohydrate kinase activity
GAY71_RS13595	COG4483	Protein conserved in bacteria
GAY71_RS13600	COG0457	Tetratricopeptide repeat
GAY71_RS13600	COG0705	Rhomboid family
GAY71_RS13610	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GAY71_RS13615	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GAY71_RS13620	COG0438	transferase activity, transferring glycosyl groups
GAY71_RS13635	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GAY71_RS13640	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GAY71_RS13645	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GAY71_RS13650	COG0581	inorganic phosphate transmembrane transporter activity
GAY71_RS13655	COG0573	inorganic phosphate transmembrane transporter activity
GAY71_RS13660	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GAY71_RS13670	COG0477	Major facilitator Superfamily
GAY71_RS13675	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GAY71_RS13680	COG2839	Protein conserved in bacteria
GAY71_RS13685	COG5521	maltodextrose utilization protein MalA
GAY71_RS13695	COG1388	LysM domain
GAY71_RS13700	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GAY71_RS13705	COG4709	membrane
GAY71_RS13710	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
GAY71_RS13715	COG0735	belongs to the Fur family
GAY71_RS13720	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GAY71_RS13730	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GAY71_RS13745	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GAY71_RS13750	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GAY71_RS13755	COG2384	SAM-dependent methyltransferase
GAY71_RS13760	COG2010	Cytochrome c
GAY71_RS13765	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GAY71_RS13770	COG0358	DNA primase activity
GAY71_RS13775	COG1671	Belongs to the UPF0178 family
GAY71_RS13780	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GAY71_RS13785	COG0517	IMP dehydrogenase activity
GAY71_RS13790	COG0751	glycine-tRNA ligase activity
GAY71_RS13795	COG0752	glycyl-tRNA synthetase alpha subunit
GAY71_RS13800	COG1381	Involved in DNA repair and RecF pathway recombination
GAY71_RS13810	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GAY71_RS13815	COG0295	cytidine deaminase activity
GAY71_RS13820	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GAY71_RS13825	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GAY71_RS13830	COG1480	7TM receptor with intracellular HD hydrolase
GAY71_RS13835	COG1702	phosphate starvation-inducible protein PhoH
GAY71_RS13840	COG0561	phosphatase activity
GAY71_RS13855	COG4864	UPF0365 protein
GAY71_RS13860	COG1030	water channel activity
GAY71_RS13865	COG1610	YqeY-like protein
GAY71_RS13870	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GAY71_RS13875	COG1283	sodium-dependent phosphate transmembrane transporter activity
GAY71_RS13880	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GAY71_RS13885	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GAY71_RS13890	COG2264	protein methyltransferase activity
GAY71_RS13895	COG0484	heat shock protein binding
GAY71_RS13900	COG0443	Heat shock 70 kDa protein
GAY71_RS13905	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GAY71_RS13910	COG1420	regulation of RNA biosynthetic process
GAY71_RS13915	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GAY71_RS13920	COG0481	GTPase activity
GAY71_RS13930	COG0860	N-Acetylmuramoyl-L-alanine amidase
GAY71_RS13935	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GAY71_RS13940	COG0268	Binds directly to 16S ribosomal RNA
GAY71_RS13945	COG1466	dna polymerase III delta subunit
GAY71_RS13960	COG2333	competence protein COMEC
GAY71_RS13960	COG0658	competence protein
GAY71_RS13965	COG2131	deaminase
GAY71_RS13970	COG1596	polysaccharide export
GAY71_RS13970	COG1555	photosystem II stabilization
GAY71_RS13975	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GAY71_RS13980	COG2226	methyltransferase
GAY71_RS13985	COG0799	negative regulation of ribosome biogenesis
GAY71_RS13990	COG1713	HD superfamily hydrolase involved in NAD metabolism
GAY71_RS13995	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GAY71_RS14000	COG1534	Rna-binding protein
GAY71_RS14005	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GAY71_RS14010	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GAY71_RS14015	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GAY71_RS14025	COG2755	lipolytic protein G-D-S-L family
GAY71_RS14030	COG5632	N-Acetylmuramoyl-L-alanine amidase
GAY71_RS14030	COG3409	Peptidoglycan-binding domain 1 protein
GAY71_RS14035	COG0398	Pfam SNARE associated Golgi protein
GAY71_RS14040	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GAY71_RS14050	COG3209	COG3209 Rhs family protein
GAY71_RS14060	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GAY71_RS14065	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GAY71_RS14070	COG0798	PFAM Bile acid sodium symporter
GAY71_RS14075	COG0346	lactoylglutathione lyase activity
GAY71_RS14080	COG0640	Transcriptional regulator
GAY71_RS14085	COG3403	YqcI/YcgG family
GAY71_RS14090	COG0457	Tetratricopeptide repeat
GAY71_RS14105	COG5444	nuclease activity
GAY71_RS14130	COG5632	N-Acetylmuramoyl-L-alanine amidase
GAY71_RS14130	COG3409	Peptidoglycan-binding domain 1 protein
GAY71_RS14135	COG4824	toxin secretion phage lysis holin
GAY71_RS14165	COG3778	Protein conserved in bacteria
GAY71_RS14170	COG3299	homolog of phage Mu protein gp47
GAY71_RS14175	COG3628	GPW Gp25 family protein
GAY71_RS14185	COG4193	domain, Protein
GAY71_RS14190	COG1652	LysM domain
GAY71_RS14195	COG3953	SLT domain
GAY71_RS14195	COG5280	Phage tail tape measure protein TP901
GAY71_RS14260	COG4653	Phage capsid family
GAY71_RS14265	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GAY71_RS14275	COG2369	cell adhesion
GAY71_RS14280	COG5518	Phage portal protein
GAY71_RS14285	COG1783	phage Terminase large subunit
GAY71_RS14290	COG5484	DNA packaging
GAY71_RS14300	COG3677	Transposase
GAY71_RS14315	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
GAY71_RS14325	COG1484	DNA-dependent DNA replication
GAY71_RS14330	COG3935	DnaD domain protein
GAY71_RS14335	COG3723	Recombinational DNA repair protein, rece pathway
GAY71_RS14340	COG5377	YqaJ viral recombinase family
GAY71_RS14370	COG1476	TRANSCRIPTIONal
GAY71_RS14375	COG3620	sequence-specific DNA binding
GAY71_RS14385	COG0563	adenylate kinase activity
GAY71_RS14390	COG2856	Zn peptidase
GAY71_RS14415	COG3223	Belongs to the PsiE family
GAY71_RS14420	COG0642	Histidine kinase
GAY71_RS14420	COG5002	protein histidine kinase activity
GAY71_RS14425	COG0745	RESPONSE REGULATOR receiver
GAY71_RS14430	COG2311	Membrane
GAY71_RS14440	COG0454	-acetyltransferase
GAY71_RS14445	COG2249	NAD(P)H dehydrogenase (quinone) activity
GAY71_RS14455	COG0730	response to heat
GAY71_RS14460	COG0425	Belongs to the sulfur carrier protein TusA family
GAY71_RS14465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GAY71_RS14465	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GAY71_RS14475	COG0425	Belongs to the sulfur carrier protein TusA family
GAY71_RS14475	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GAY71_RS14485	COG2210	Belongs to the sulfur carrier protein TusA family
GAY71_RS14490	COG1937	Protein conserved in bacteria
GAY71_RS14495	COG0662	Cupin 2, conserved barrel domain protein
GAY71_RS14505	COG4978	Transcriptional regulator
GAY71_RS14505	COG0789	Transcriptional regulator
GAY71_RS14510	COG2814	Major facilitator Superfamily
GAY71_RS14515	COG0456	acetyltransferase
GAY71_RS14520	COG1253	flavin adenine dinucleotide binding
GAY71_RS14530	COG0697	spore germination
GAY71_RS14535	COG0583	DNA-binding transcription factor activity
GAY71_RS14540	COG2072	flavoprotein involved in K transport
GAY71_RS14545	COG1230	cation diffusion facilitator family transporter
GAY71_RS14550	COG1942	4-Oxalocrotonate Tautomerase
GAY71_RS14555	COG0583	DNA-binding transcription factor activity
GAY71_RS14565	COG1114	Component of the transport system for branched-chain amino acids
GAY71_RS14570	COG1687	branched-chain amino acid
GAY71_RS14575	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GAY71_RS14580	COG1522	sequence-specific DNA binding
GAY71_RS14585	COG2732	(Barnase) inhibitor
GAY71_RS14590	COG2124	cytochrome p450
GAY71_RS14595	COG1335	isochorismatase
GAY71_RS14610	COG2318	DinB family
GAY71_RS14620	COG2070	2-Nitropropane dioxygenase
GAY71_RS14625	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GAY71_RS14645	COG3443	Belongs to the bacterial solute-binding protein 9 family
GAY71_RS14650	COG1595	DNA-templated transcription, initiation
GAY71_RS14655	COG0667	Aldo Keto reductase
GAY71_RS14660	COG2851	Citrate transporter
GAY71_RS14665	COG0583	DNA-binding transcription factor activity
GAY71_RS14670	COG2828	Protein conserved in bacteria
GAY71_RS14675	COG3409	Peptidoglycan-binding domain 1 protein
GAY71_RS14680	COG5566	PFAM Mor transcription activator
GAY71_RS14685	COG0596	Alpha beta hydrolase
GAY71_RS14690	COG4991	sh3 domain protein
GAY71_RS14695	COG4991	sh3 domain protein
GAY71_RS14705	COG0346	lactoylglutathione lyase activity
GAY71_RS14715	COG5577	PFAM Coat F domain
GAY71_RS14720	COG1063	alcohol dehydrogenase
GAY71_RS14730	COG5577	PFAM Coat F domain
GAY71_RS14735	COG0789	Transcriptional regulator
GAY71_RS14745	COG1064	alcohol dehydrogenase
GAY71_RS14750	COG0693	protein deglycase activity
GAY71_RS14755	COG1621	beta-fructofuranosidase activity
GAY71_RS14760	COG3716	PTS system mannose fructose sorbose family IID component
GAY71_RS14765	COG3715	PTS system
GAY71_RS14770	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GAY71_RS14775	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GAY71_RS14780	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GAY71_RS14780	COG3933	PFAM sigma-54 factor interaction domain-containing protein
GAY71_RS14790	COG1113	amino acid transport
GAY71_RS14795	COG1280	lysine exporter protein (LysE YggA)
GAY71_RS14800	COG1378	Sugar-specific transcriptional regulator TrmB
GAY71_RS14805	COG1595	DNA-templated transcription, initiation
GAY71_RS14815	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GAY71_RS14815	COG2755	lipolytic protein G-D-S-L family
GAY71_RS14825	COG2124	cytochrome p450
GAY71_RS14825	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GAY71_RS14830	COG1309	transcriptional regulator
GAY71_RS14835	COG2226	methyltransferase
GAY71_RS14850	COG2116	formate transmembrane transporter activity
GAY71_RS14855	COG5609	conserved protein (DUF2294)
GAY71_RS14860	COG3383	formate dehydrogenase (NAD+) activity
GAY71_RS14865	COG2427	Protein of unknown function (DUF1641)
GAY71_RS14875	COG0626	cystathionine gamma-synthase activity
GAY71_RS14880	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GAY71_RS14885	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GAY71_RS14890	COG2226	methyltransferase
GAY71_RS14905	COG0768	penicillin binding
GAY71_RS14910	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GAY71_RS14915	COG0572	uridine kinase
GAY71_RS14935	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GAY71_RS14940	COG3906	Belongs to the UPF0473 family
GAY71_RS14945	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GAY71_RS14950	COG4472	Bacterial protein of unknown function (DUF965)
GAY71_RS14955	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GAY71_RS14960	COG0628	permease
GAY71_RS14965	COG1126	abc transporter atp-binding protein
GAY71_RS14970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GAY71_RS14975	COG0765	amino acid transport
GAY71_RS14980	COG0765	amino acid transport
GAY71_RS14995	COG3881	PFAM PRC-barrel domain
GAY71_RS15000	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GAY71_RS15005	COG0457	Tetratricopeptide repeat
GAY71_RS15010	COG0482	sulfurtransferase activity
GAY71_RS15015	COG1104	cysteine desulfurase activity
GAY71_RS15020	COG1959	2 iron, 2 sulfur cluster binding
GAY71_RS15025	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GAY71_RS15030	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GAY71_RS15040	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GAY71_RS15045	COG0124	histidyl-tRNA synthetase
GAY71_RS15055	COG0860	N-Acetylmuramoyl-L-alanine amidase
GAY71_RS15055	COG3103	Sh3 type 3 domain protein
GAY71_RS15055	COG4991	sh3 domain protein
GAY71_RS15060	COG1490	D-aminoacyl-tRNA deacylase activity
GAY71_RS15065	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GAY71_RS15070	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GAY71_RS15075	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GAY71_RS15075	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GAY71_RS15080	COG5416	Lipopolysaccharide assembly protein A domain
GAY71_RS15085	COG0490	domain, Protein
GAY71_RS15090	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GAY71_RS15090	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GAY71_RS15100	COG2244	polysaccharide biosynthetic process
GAY71_RS15105	COG2323	membrane
GAY71_RS15115	COG1862	Preprotein translocase
GAY71_RS15120	COG0343	queuine tRNA-ribosyltransferase activity
GAY71_RS15125	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GAY71_RS15135	COG2255	four-way junction helicase activity
GAY71_RS15140	COG0632	four-way junction helicase activity
GAY71_RS15150	COG2814	Major facilitator Superfamily
GAY71_RS15155	COG0673	inositol 2-dehydrogenase activity
GAY71_RS15160	COG2112	serine threonine protein kinase
GAY71_RS15180	COG1115	amino acid carrier protein
GAY71_RS15185	COG0217	transcriptional regulatory protein
GAY71_RS15195	COG1388	LysM domain
GAY71_RS15200	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GAY71_RS15205	COG0157	Belongs to the NadC ModD family
GAY71_RS15210	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GAY71_RS15215	COG1104	cysteine desulfurase activity
GAY71_RS15220	COG1827	regulation of RNA biosynthetic process
GAY71_RS15225	COG0077	Prephenate dehydratase
GAY71_RS15230	COG4492	Belongs to the UPF0735 family
GAY71_RS15235	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GAY71_RS15240	COG3290	protein histidine kinase activity
GAY71_RS15250	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GAY71_RS15255	COG2868	ribosomal protein
GAY71_RS15260	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GAY71_RS15265	COG1994	Peptidase M50
GAY71_RS15270	COG0739	heme binding
GAY71_RS15275	COG2894	cell division
GAY71_RS15280	COG0850	regulation of cytokinetic process
GAY71_RS15285	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GAY71_RS15290	COG1792	Involved in formation and maintenance of cell shape
GAY71_RS15295	COG1077	Cell shape determining protein MreB Mrl
GAY71_RS15300	COG2003	Belongs to the UPF0758 family
GAY71_RS15305	COG0424	maF-like protein
GAY71_RS15315	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GAY71_RS15320	COG0285	dihydrofolate synthase activity
GAY71_RS15325	COG0525	valine-tRNA ligase activity
GAY71_RS15335	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GAY71_RS15340	COG1388	LysM domain
GAY71_RS15345	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GAY71_RS15350	COG0113	porphobilinogen synthase activity
GAY71_RS15355	COG1587	Uroporphyrinogen-III synthase
GAY71_RS15360	COG0181	hydroxymethylbilane synthase activity
GAY71_RS15365	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GAY71_RS15370	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GAY71_RS15380	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GAY71_RS15385	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GAY71_RS15390	COG0470	DNA polymerase III
GAY71_RS15390	COG1067	ATP-dependent peptidase activity
GAY71_RS15395	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GAY71_RS15400	COG0544	peptidyl-prolyl cis-trans isomerase activity
GAY71_RS15405	COG0457	Tetratricopeptide repeat
GAY71_RS15405	COG1477	protein flavinylation
GAY71_RS15410	COG0066	3-isopropylmalate dehydratase activity
GAY71_RS15415	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GAY71_RS15420	COG0473	3-isopropylmalate dehydrogenase activity
GAY71_RS15425	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GAY71_RS15430	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GAY71_RS15435	COG0440	acetolactate synthase activity
GAY71_RS15440	COG0028	Belongs to the TPP enzyme family
GAY71_RS15450	COG0454	-acetyltransferase
GAY71_RS15455	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
GAY71_RS15465	COG0622	Phosphoesterase
GAY71_RS15470	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GAY71_RS15475	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GAY71_RS15480	COG5401	PFAM Sporulation and spore germination
GAY71_RS15485	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GAY71_RS15490	COG1846	Transcriptional regulator
GAY71_RS15495	COG2197	response regulator
GAY71_RS15500	COG0824	Thioesterase
GAY71_RS15505	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GAY71_RS15510	COG1053	succinate dehydrogenase
GAY71_RS15515	COG2009	succinate dehydrogenase
GAY71_RS15520	COG1719	4-vinyl reductase, 4VR
GAY71_RS15525	COG0527	aspartate kinase activity
GAY71_RS15530	COG0322	excinuclease ABC activity
GAY71_RS15535	COG3118	belongs to the thioredoxin family
GAY71_RS15540	COG3534	alpha-L-arabinofuranosidase
GAY71_RS15545	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GAY71_RS15550	COG2086	electron transfer activity
GAY71_RS15555	COG1024	Enoyl-CoA hydratase
GAY71_RS15560	COG1309	transcriptional regulator
GAY71_RS15565	COG0318	PFAM AMP-dependent synthetase and ligase
GAY71_RS15570	COG3766	membrane
GAY71_RS15575	COG1193	negative regulation of DNA recombination
GAY71_RS15580	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GAY71_RS15580	COG1796	DNA polymerase
GAY71_RS15585	COG1286	toxin biosynthetic process
GAY71_RS15590	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GAY71_RS15595	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GAY71_RS15600	COG0072	phenylalanine-tRNA ligase activity
GAY71_RS15600	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GAY71_RS15605	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GAY71_RS15615	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GAY71_RS15625	COG3835	regulator
GAY71_RS15630	COG0277	FAD linked oxidase domain protein
GAY71_RS15635	COG0247	lactate metabolic process
GAY71_RS15640	COG0346	lactoylglutathione lyase activity
GAY71_RS15650	COG1966	Carbon starvation protein
GAY71_RS15655	COG3534	alpha-L-arabinofuranosidase
GAY71_RS15660	COG0395	ABC-type sugar transport system, permease component
GAY71_RS15665	COG1175	transmembrane transport
GAY71_RS15670	COG1653	transport
GAY71_RS15675	COG0371	Dehydrogenase
GAY71_RS15680	COG0647	UMP catabolic process
GAY71_RS15685	COG0235	Class ii aldolase
GAY71_RS15690	COG1069	ribulokinase activity
GAY71_RS15695	COG2160	L-arabinose isomerase activity
GAY71_RS15700	COG3507	Belongs to the glycosyl hydrolase 43 family
GAY71_RS15705	COG1363	Peptidase, m42
GAY71_RS15715	COG3326	Membrane
GAY71_RS15720	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GAY71_RS15725	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GAY71_RS15730	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GAY71_RS15740	COG1346	cytolysis
GAY71_RS15745	COG1380	Effector of murein hydrolase LrgA
GAY71_RS15750	COG3279	Response regulator of the LytR AlgR family
GAY71_RS15755	COG3275	phosphorelay sensor kinase activity
GAY71_RS15765	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GAY71_RS15775	COG0398	Pfam SNARE associated Golgi protein
GAY71_RS15780	COG1484	DNA-dependent DNA replication
GAY71_RS15785	COG3611	Membrane attachment protein
GAY71_RS15790	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GAY71_RS15795	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GAY71_RS15800	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GAY71_RS15805	COG1733	regulation of RNA biosynthetic process
GAY71_RS15810	COG2814	Major facilitator Superfamily
GAY71_RS15815	COG0656	L-ascorbic acid biosynthetic process
GAY71_RS15820	COG0237	dephospho-CoA kinase activity
GAY71_RS15825	COG1971	Probably functions as a manganese efflux pump
GAY71_RS15830	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GAY71_RS15835	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GAY71_RS15835	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GAY71_RS15840	COG5002	protein histidine kinase activity
GAY71_RS15845	COG0745	RESPONSE REGULATOR receiver
GAY71_RS15850	COG0039	L-malate dehydrogenase activity
GAY71_RS15855	COG0538	isocitrate dehydrogenase activity
GAY71_RS15860	COG0372	Belongs to the citrate synthase family
GAY71_RS15865	COG2707	UPF0756 membrane protein
GAY71_RS15870	COG0628	permease
GAY71_RS15875	COG3030	protein affecting phage T7 exclusion by the F plasmid
GAY71_RS15880	COG0469	pyruvate kinase activity
GAY71_RS15885	COG0205	6-phosphofructokinase activity
GAY71_RS15890	COG0825	malonyl-CoA metabolic process
GAY71_RS15895	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GAY71_RS15900	COG0281	malic enzyme
GAY71_RS15905	COG0587	DNA-directed DNA polymerase activity
GAY71_RS15925	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GAY71_RS15935	COG4109	DRTGG domain
GAY71_RS15940	COG0730	response to heat
GAY71_RS15945	COG1473	amidohydrolase
GAY71_RS15950	COG0196	riboflavin kinase activity
GAY71_RS15955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GAY71_RS15960	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GAY71_RS15965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GAY71_RS15970	COG1126	abc transporter atp-binding protein
GAY71_RS15975	COG0765	amino acid transport
GAY71_RS15980	COG0765	amino acid transport
GAY71_RS15985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GAY71_RS15990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GAY71_RS15995	COG0454	-acetyltransferase
GAY71_RS16000	COG0583	DNA-binding transcription factor activity
GAY71_RS16005	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GAY71_RS16010	COG1028	Short-chain dehydrogenase reductase Sdr
GAY71_RS16020	COG0165	Argininosuccinate lyase
GAY71_RS16025	COG0137	argininosuccinate synthase activity
GAY71_RS16030	COG0521	Mo-molybdopterin cofactor biosynthetic process
GAY71_RS16035	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GAY71_RS16045	COG0827	DNA restriction-modification system
GAY71_RS16050	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GAY71_RS16055	COG3874	Sporulation protein YtfJ
GAY71_RS16065	COG1714	RDD family
GAY71_RS16070	COG0616	signal peptide processing
GAY71_RS16075	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GAY71_RS16080	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GAY71_RS16085	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GAY71_RS16095	COG0301	tRNA thio-modification
GAY71_RS16100	COG1104	cysteine desulfurase activity
GAY71_RS16105	COG1114	Component of the transport system for branched-chain amino acids
GAY71_RS16110	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GAY71_RS16115	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GAY71_RS16120	COG1309	transcriptional regulator
GAY71_RS16125	COG1956	GAF domain-containing protein
GAY71_RS16130	COG2199	diguanylate cyclase activity
GAY71_RS16130	COG2203	Gaf domain
GAY71_RS16140	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GAY71_RS16145	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GAY71_RS16150	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GAY71_RS16155	COG0454	-acetyltransferase
GAY71_RS16160	COG0517	IMP dehydrogenase activity
GAY71_RS16165	COG0123	including yeast histone deacetylase and acetoin utilization protein
GAY71_RS16170	COG1360	Flagellar Motor Protein
GAY71_RS16175	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GAY71_RS16180	COG1609	Transcriptional regulator
GAY71_RS16185	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GAY71_RS16185	COG1605	Chorismate mutase
GAY71_RS16190	COG3118	belongs to the thioredoxin family
GAY71_RS16195	COG4980	gas vesicle protein
GAY71_RS16200	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GAY71_RS16205	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GAY71_RS16210	COG1674	ftsk spoiiie
GAY71_RS16215	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GAY71_RS16220	COG4848	Belongs to the UPF0354 family
GAY71_RS16225	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GAY71_RS16240	COG1363	Peptidase, m42
GAY71_RS16245	COG5584	Small secreted protein
GAY71_RS16250	COG0281	malic enzyme
GAY71_RS16255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GAY71_RS16260	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GAY71_RS16270	COG0510	thiamine kinase activity
GAY71_RS16275	COG1523	belongs to the glycosyl hydrolase 13 family
GAY71_RS16280	COG1597	lipid kinase activity
GAY71_RS16290	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GAY71_RS16295	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GAY71_RS16300	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GAY71_RS16305	COG2252	PERMEase
GAY71_RS16310	COG4473	ABC transporter
GAY71_RS16315	COG1131	(ABC) transporter
GAY71_RS16320	COG1349	DNA-binding transcription factor activity
GAY71_RS16325	COG1187	pseudouridine synthase activity
GAY71_RS16330	COG2244	polysaccharide biosynthetic process
GAY71_RS16335	COG2081	HI0933 family
GAY71_RS16340	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GAY71_RS16350	COG5578	integral membrane protein
GAY71_RS16355	COG0673	inositol 2-dehydrogenase activity
GAY71_RS16360	COG1653	transport
GAY71_RS16365	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GAY71_RS16370	COG4209	transmembrane transport
GAY71_RS16375	COG2207	Transcriptional regulator
GAY71_RS16380	COG1653	transport
GAY71_RS16385	COG0395	ABC-type sugar transport system, permease component
GAY71_RS16390	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GAY71_RS16395	COG2124	cytochrome p450
GAY71_RS16400	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GAY71_RS16405	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GAY71_RS16410	COG0156	8-amino-7-oxononanoate synthase activity
GAY71_RS16415	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GAY71_RS16420	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
GAY71_RS16425	COG1073	alpha beta
GAY71_RS16450	COG1486	melibiose metabolic process
GAY71_RS16455	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GAY71_RS16460	COG0495	leucyl-tRNA aminoacylation
GAY71_RS16470	COG2202	Pas domain
GAY71_RS16470	COG1366	Belongs to the anti-sigma-factor antagonist family
GAY71_RS16475	COG2814	Major facilitator Superfamily
GAY71_RS16480	COG2433	Pfam Transposase IS66
GAY71_RS16485	COG0577	efflux transmembrane transporter activity
GAY71_RS16490	COG1136	(ABC) transporter
GAY71_RS16495	COG2205	protein histidine kinase activity
GAY71_RS16500	COG0745	RESPONSE REGULATOR receiver
GAY71_RS16505	COG0577	efflux transmembrane transporter activity
GAY71_RS16510	COG1136	(ABC) transporter
GAY71_RS16525	COG1131	(ABC) transporter
GAY71_RS16530	COG1725	Transcriptional regulator
GAY71_RS16545	COG1242	4 iron, 4 sulfur cluster binding
GAY71_RS16550	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GAY71_RS16560	COG2267	carboxylic ester hydrolase activity
GAY71_RS16565	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GAY71_RS16570	COG1113	amino acid transport
GAY71_RS16575	COG0367	asparagine synthase
GAY71_RS16580	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GAY71_RS16585	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GAY71_RS16595	COG1506	peptidase
GAY71_RS16600	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GAY71_RS16605	COG1116	anion transmembrane transporter activity
GAY71_RS16610	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GAY71_RS16615	COG0494	nUDIX hydrolase
GAY71_RS16620	COG4824	toxin secretion phage lysis holin
GAY71_RS16625	COG0783	Belongs to the Dps family
GAY71_RS16640	COG1854	S-ribosylhomocysteine lyase activity
GAY71_RS16645	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GAY71_RS16650	COG0288	reversible hydration of carbon dioxide
GAY71_RS16655	COG0254	rRNA binding
GAY71_RS16660	COG1271	oxidase subunit
GAY71_RS16665	COG1294	oxidase, subunit
GAY71_RS16675	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GAY71_RS16680	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GAY71_RS16680	COG1321	iron dependent repressor
GAY71_RS16685	COG1121	(ABC) transporter
GAY71_RS16695	COG4948	Mandelate Racemase Muconate Lactonizing
GAY71_RS16700	COG0318	PFAM AMP-dependent synthetase and ligase
GAY71_RS16705	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GAY71_RS16710	COG0596	Alpha beta hydrolase
GAY71_RS16715	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GAY71_RS16720	COG1169	isochorismate synthase
GAY71_RS16725	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GAY71_RS16730	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GAY71_RS16735	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GAY71_RS16740	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GAY71_RS16745	COG0438	transferase activity, transferring glycosyl groups
GAY71_RS16755	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GAY71_RS16760	COG0438	transferase activity, transferring glycosyl groups
GAY71_RS16765	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GAY71_RS16770	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
GAY71_RS16775	COG0058	SHG alpha-glucan phosphorylase activity
GAY71_RS16780	COG0297	glycogen (starch) synthase activity
GAY71_RS16785	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GAY71_RS16790	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GAY71_RS16795	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GAY71_RS16920	COG3859	Proton-coupled thiamine transporter YuaJ
GAY71_RS16925	COG1247	-acetyltransferase
GAY71_RS16930	COG2268	Band 7 protein
GAY71_RS16935	COG1585	Membrane protein implicated in regulation of membrane protease activity
GAY71_RS16940	COG2318	DinB family
GAY71_RS16950	COG1454	alcohol dehydrogenase
GAY71_RS16960	COG1510	regulation of RNA biosynthetic process
GAY71_RS16970	COG0569	domain protein
GAY71_RS16975	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GAY71_RS16980	COG4682	membrane
GAY71_RS16985	COG1705	Flagellar rod assembly protein muramidase FlgJ
GAY71_RS16990	COG0477	Major facilitator Superfamily
GAY71_RS16995	COG5553	Cysteine dioxygenase type I
GAY71_RS17005	COG1968	undecaprenyl-diphosphatase activity
GAY71_RS17010	COG0628	permease
GAY71_RS17015	COG0673	inositol 2-dehydrogenase activity
GAY71_RS17020	COG4806	L-rhamnose isomerase
GAY71_RS17025	COG3254	rhamnose metabolic process
GAY71_RS17030	COG1070	Carbohydrate kinase
GAY71_RS17035	COG1349	DNA-binding transcription factor activity
GAY71_RS17040	COG3347	Dehydrogenase
GAY71_RS17040	COG1028	Short-chain dehydrogenase reductase Sdr
GAY71_RS17045	COG0840	transmembrane signaling receptor activity
GAY71_RS17050	COG0840	transmembrane signaling receptor activity
GAY71_RS17055	COG0840	transmembrane signaling receptor activity
GAY71_RS17060	COG0840	transmembrane signaling receptor activity
GAY71_RS17075	COG0432	Pfam Uncharacterised protein family UPF0047
GAY71_RS17085	COG0366	Alpha amylase catalytic
GAY71_RS17090	COG1253	flavin adenine dinucleotide binding
GAY71_RS17095	COG2738	Putative neutral zinc metallopeptidase
GAY71_RS17110	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GAY71_RS17125	COG0166	Belongs to the GPI family
GAY71_RS17130	COG1979	alcohol dehydrogenase
GAY71_RS17135	COG1979	alcohol dehydrogenase
GAY71_RS17140	COG2155	Conserved Protein
GAY71_RS17145	COG1098	S1 RNA binding domain
GAY71_RS17150	COG0436	Aminotransferase
GAY71_RS17155	COG1522	sequence-specific DNA binding
GAY71_RS17160	COG2267	carboxylic ester hydrolase activity
GAY71_RS17170	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GAY71_RS17175	COG2205	protein histidine kinase activity
GAY71_RS17185	COG5018	Exonuclease
GAY71_RS17195	COG2814	Major facilitator Superfamily
GAY71_RS17200	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GAY71_RS17205	COG3011	Protein conserved in bacteria
GAY71_RS17215	COG3290	protein histidine kinase activity
GAY71_RS17220	COG4565	transcriptional regulatory protein
GAY71_RS17245	COG3493	citrate carrier protein
GAY71_RS17255	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GAY71_RS17255	COG2111	Na H antiporter
GAY71_RS17260	COG2111	Na H antiporter
GAY71_RS17265	COG1006	Multisubunit Na H antiporter MnhC subunit
GAY71_RS17270	COG0651	ATP synthesis coupled electron transport
GAY71_RS17275	COG1863	multisubunit Na H antiporter MnhE subunit
GAY71_RS17280	COG2212	antiporter activity
GAY71_RS17285	COG1320	monovalent cation:proton antiporter activity
GAY71_RS17290	COG2050	protein possibly involved in aromatic compounds catabolism
GAY71_RS17295	COG2197	response regulator
GAY71_RS17300	COG4585	Histidine kinase
GAY71_RS17310	COG0142	geranyltranstransferase activity
GAY71_RS17330	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GAY71_RS17335	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GAY71_RS17340	COG1335	isochorismatase
GAY71_RS17345	COG5506	Protein of unknown function (DUF1694)
GAY71_RS17360	COG0628	permease
GAY71_RS17375	COG1418	mRNA catabolic process
GAY71_RS17380	COG1028	Short-chain dehydrogenase reductase Sdr
GAY71_RS17390	COG1511	domain protein
GAY71_RS17395	COG1674	ftsk spoiiie
GAY71_RS17395	COG0433	COG0433 Predicted ATPase
GAY71_RS17400	COG4499	WXG100 protein secretion system (Wss), protein YukC
GAY71_RS17405	COG5417	Belongs to the EsaB family
GAY71_RS17410	COG4842	Belongs to the WXG100 family
GAY71_RS17415	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GAY71_RS17415	COG2508	Transcriptional regulator
GAY71_RS17420	COG0686	Belongs to the AlaDH PNT family
GAY71_RS17425	COG5634	Uncharacterized conserved protein (DUF2278)
GAY71_RS17430	COG3251	PFAM MbtH domain protein
GAY71_RS17435	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GAY71_RS17440	COG1535	isochorismatase
GAY71_RS17440	COG3433	isochorismatase activity
GAY71_RS17445	COG1021	2,3-dihydroxybenzoate-AMP ligase
GAY71_RS17450	COG1169	isochorismate synthase
GAY71_RS17455	COG1028	Short-chain dehydrogenase reductase Sdr
GAY71_RS17460	COG2819	hydrolase of the alpha beta superfamily
GAY71_RS17465	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GAY71_RS17470	COG1268	BioY protein
GAY71_RS17475	COG2056	Na+-H+ antiporter family
GAY71_RS17480	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GAY71_RS17485	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
GAY71_RS17490	COG3584	3D domain protein
GAY71_RS17505	COG1252	NADH dehydrogenase
GAY71_RS17510	COG0492	ferredoxin-NADP+ reductase activity
GAY71_RS17520	COG0516	GMP reductase activity
GAY71_RS17525	COG2808	Putative FMN-binding domain
GAY71_RS17530	COG0456	acetyltransferase
GAY71_RS17535	COG0316	Belongs to the HesB IscA family
GAY71_RS17540	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GAY71_RS17545	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GAY71_RS17550	COG4844	belongs to the
GAY71_RS17555	COG1252	NADH dehydrogenase
GAY71_RS17560	COG4837	Protein of unknown function (DUF1462)
GAY71_RS17565	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GAY71_RS17570	COG0823	Involved in the tonB-independent uptake of proteins
GAY71_RS17570	COG1506	peptidase
GAY71_RS17570	COG4946	Tricorn protease homolog
GAY71_RS17575	COG0083	homoserine kinase activity
GAY71_RS17580	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GAY71_RS17585	COG0460	homoserine dehydrogenase
GAY71_RS17590	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GAY71_RS17595	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GAY71_RS17600	COG0647	UMP catabolic process
GAY71_RS17605	COG2445	Protein of unknown function DUF86
GAY71_RS17610	COG4470	Protein conserved in bacteria
GAY71_RS17620	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GAY71_RS17625	COG0739	heme binding
GAY71_RS17635	COG3377	Domain of unknown function (DUF1805)
GAY71_RS17640	COG0737	Belongs to the 5'-nucleotidase family
GAY71_RS17645	COG0730	response to heat
GAY71_RS17650	COG1801	Protein of unknown function DUF72
GAY71_RS17660	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GAY71_RS17665	COG2508	Transcriptional regulator
GAY71_RS17670	COG2233	PERMEase
GAY71_RS17675	COG2233	PERMEase
GAY71_RS17680	COG3195	allantoin biosynthetic process
GAY71_RS17680	COG3648	Uricase
GAY71_RS17685	COG2351	hydroxyisourate hydrolase activity
GAY71_RS17695	COG2080	2 iron, 2 sulfur cluster binding
GAY71_RS17700	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GAY71_RS17705	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GAY71_RS17710	COG2068	MobA-Related Protein
GAY71_RS17715	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GAY71_RS17720	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GAY71_RS17725	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GAY71_RS17735	COG2356	endonuclease I
GAY71_RS17740	COG3842	ATPase activity
GAY71_RS17745	COG2188	Transcriptional regulator
GAY71_RS17750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GAY71_RS17755	COG0395	ABC-type sugar transport system, permease component
GAY71_RS17760	COG1175	transmembrane transport
GAY71_RS17765	COG1653	transport
GAY71_RS17770	COG2222	sugar isomerase
GAY71_RS17775	COG0322	excinuclease ABC activity
GAY71_RS17780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GAY71_RS17795	COG0346	lactoylglutathione lyase activity
GAY71_RS17800	COG0640	Transcriptional regulator
GAY71_RS17805	COG0719	Fe-S assembly protein
GAY71_RS17810	COG0822	iron-sulfur transferase activity
GAY71_RS17815	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GAY71_RS17820	COG0719	Fe-S assembly protein
GAY71_RS17825	COG0396	ATPase activity
GAY71_RS17835	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GAY71_RS17840	COG1464	Belongs to the NlpA lipoprotein family
GAY71_RS17845	COG2011	ABC-type metal ion transport system permease component
GAY71_RS17850	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GAY71_RS17860	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GAY71_RS17865	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GAY71_RS17875	COG0509	glycine decarboxylation via glycine cleavage system
GAY71_RS17880	COG1393	Belongs to the ArsC family
GAY71_RS17885	COG1960	acyl-CoA dehydrogenase activity
GAY71_RS17890	COG0183	Belongs to the thiolase family
GAY71_RS17895	COG1250	3-hydroxyacyl-CoA dehydrogenase
GAY71_RS17895	COG1024	Enoyl-CoA hydratase
GAY71_RS17905	COG0506	proline dehydrogenase activity
GAY71_RS17915	COG5577	PFAM Coat F domain
GAY71_RS17920	COG1846	Transcriptional regulator
GAY71_RS17925	COG0477	Major facilitator Superfamily
GAY71_RS17930	COG1942	4-Oxalocrotonate Tautomerase
GAY71_RS17940	COG0583	DNA-binding transcription factor activity
GAY71_RS17950	COG1120	ATPase activity
GAY71_RS17965	COG1028	Short-chain dehydrogenase reductase Sdr
GAY71_RS17970	COG0783	Belongs to the Dps family
GAY71_RS17975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GAY71_RS17980	COG0745	RESPONSE REGULATOR receiver
GAY71_RS17985	COG2205	protein histidine kinase activity
GAY71_RS17985	COG2770	Histidine kinase
GAY71_RS17995	COG1309	transcriptional regulator
GAY71_RS18000	COG0114	fumarate hydratase activity
GAY71_RS18010	COG0697	spore germination
GAY71_RS18015	COG0814	amino acid
GAY71_RS18025	COG2197	response regulator
GAY71_RS18030	COG4585	Histidine kinase
GAY71_RS18035	COG4758	membrane
GAY71_RS18040	COG3595	metallopeptidase activity
GAY71_RS18045	COG1842	Phage shock protein A
GAY71_RS18050	COG4758	membrane
GAY71_RS18055	COG2814	Major facilitator Superfamily
GAY71_RS18060	COG2096	Adenosyltransferase
GAY71_RS18065	COG1120	ATPase activity
GAY71_RS18070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GAY71_RS18075	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GAY71_RS18080	COG1028	Short-chain dehydrogenase reductase Sdr
GAY71_RS18085	COG3386	PFAM SMP-30 Gluconolaconase
GAY71_RS18090	COG2205	protein histidine kinase activity
GAY71_RS18095	COG0745	RESPONSE REGULATOR receiver
GAY71_RS18105	COG1191	sigma factor activity
GAY71_RS18115	COG2140	Oxalate decarboxylase
GAY71_RS18125	COG0577	efflux transmembrane transporter activity
GAY71_RS18130	COG1136	(ABC) transporter
GAY71_RS18135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GAY71_RS18140	COG1120	ATPase activity
GAY71_RS18145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GAY71_RS18150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GAY71_RS18155	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GAY71_RS18160	COG0531	amino acid
GAY71_RS18170	COG1988	membrane-bound metal-dependent
GAY71_RS18175	COG1368	sulfuric ester hydrolase activity
GAY71_RS18180	COG1910	domain protein
GAY71_RS18185	COG0725	ABC transporter, periplasmic molybdate-binding protein
GAY71_RS18190	COG4149	molybdate abc transporter
GAY71_RS18195	COG0656	L-ascorbic acid biosynthetic process
GAY71_RS18205	COG0025	NhaP-type Na H and K H
GAY71_RS18210	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GAY71_RS18215	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GAY71_RS18220	COG3973	AAA domain
GAY71_RS18225	COG2860	membrane
GAY71_RS18230	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GAY71_RS18235	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GAY71_RS18240	COG2217	Heavy metal translocating P-type atpase
GAY71_RS18245	COG2217	Heavy metal translocating P-type atpase
GAY71_RS18250	COG2608	mercury ion transmembrane transporter activity
GAY71_RS18255	COG1937	Protein conserved in bacteria
GAY71_RS18260	COG0673	inositol 2-dehydrogenase activity
GAY71_RS18265	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GAY71_RS18270	COG1289	transmembrane transporter activity
GAY71_RS18280	COG2076	Multidrug Resistance protein
GAY71_RS18285	COG1309	transcriptional regulator
GAY71_RS18290	COG1028	Short-chain dehydrogenase reductase Sdr
GAY71_RS18300	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GAY71_RS18305	COG0557	exoribonuclease II activity
GAY71_RS18310	COG1647	Serine aminopeptidase, S33
GAY71_RS18315	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GAY71_RS18320	COG0596	Alpha beta hydrolase
GAY71_RS18325	COG1476	TRANSCRIPTIONal
GAY71_RS18330	COG1396	sequence-specific DNA binding
GAY71_RS18335	COG1396	sequence-specific DNA binding
GAY71_RS18340	COG1733	regulation of RNA biosynthetic process
GAY71_RS18345	COG0840	transmembrane signaling receptor activity
GAY71_RS18350	COG1174	glycine betaine transport
GAY71_RS18355	COG1732	Glycine betaine
GAY71_RS18360	COG1174	glycine betaine transport
GAY71_RS18365	COG0517	IMP dehydrogenase activity
GAY71_RS18365	COG1125	glycine betaine transport
GAY71_RS18370	COG1510	regulation of RNA biosynthetic process
GAY71_RS18390	COG5658	integral membrane protein
GAY71_RS18395	COG0640	Transcriptional regulator
GAY71_RS18400	COG1174	glycine betaine transport
GAY71_RS18405	COG1732	Glycine betaine
GAY71_RS18410	COG1174	glycine betaine transport
GAY71_RS18415	COG1125	glycine betaine transport
GAY71_RS18415	COG0517	IMP dehydrogenase activity
GAY71_RS18420	COG1510	regulation of RNA biosynthetic process
GAY71_RS18425	COG2095	MarC family integral membrane protein
GAY71_RS18435	COG3064	Membrane
GAY71_RS18440	COG4640	response to antibiotic
GAY71_RS18445	COG0456	acetyltransferase
GAY71_RS18450	COG0148	phosphopyruvate hydratase activity
GAY71_RS18455	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GAY71_RS18460	COG0149	triose-phosphate isomerase activity
GAY71_RS18465	COG0126	phosphoglycerate kinase activity
GAY71_RS18470	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GAY71_RS18475	COG2390	Transcriptional regulator
GAY71_RS18480	COG2814	Major facilitator Superfamily
GAY71_RS18485	COG1609	Transcriptional regulator
GAY71_RS18490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GAY71_RS18495	COG0583	DNA-binding transcription factor activity
GAY71_RS18500	COG0697	spore germination
GAY71_RS18505	COG1113	amino acid transport
GAY71_RS18510	COG3858	chitin binding
GAY71_RS18515	COG1556	Lactate utilization protein
GAY71_RS18520	COG1139	Iron-sulfur cluster binding protein
GAY71_RS18525	COG0247	lactate metabolic process
GAY71_RS18530	COG2197	response regulator
GAY71_RS18535	COG4585	Histidine kinase
GAY71_RS18540	COG0842	Transport permease protein
GAY71_RS18545	COG1131	(ABC) transporter
GAY71_RS18550	COG0596	Alpha beta hydrolase
GAY71_RS18555	COG2208	phosphoserine phosphatase activity
GAY71_RS18560	COG3867	Arabinogalactan endo-beta-1,4-galactanase
GAY71_RS18565	COG1874	Beta-galactosidase
GAY71_RS18570	COG3833	ABC-type maltose transport systems, permease component
GAY71_RS18575	COG1175	transmembrane transport
GAY71_RS18580	COG2182	Extracellular solute-binding protein
GAY71_RS18585	COG1609	Transcriptional regulator
GAY71_RS18590	COG2186	Transcriptional regulator
GAY71_RS18595	COG1620	l-lactate permease
GAY71_RS18600	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GAY71_RS18610	COG5039	Polysaccharide pyruvyl transferase
GAY71_RS18615	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GAY71_RS18620	COG0110	maltose O-acetyltransferase activity
GAY71_RS18625	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GAY71_RS18630	COG2244	polysaccharide biosynthetic process
GAY71_RS18635	COG1216	Glycosyl transferase, family 2
GAY71_RS18640	COG5039	Polysaccharide pyruvyl transferase
GAY71_RS18645	COG1216	Glycosyl transferase, family 2
GAY71_RS18655	COG0438	transferase activity, transferring glycosyl groups
GAY71_RS18660	COG1215	transferase activity, transferring glycosyl groups
GAY71_RS18665	COG0438	transferase activity, transferring glycosyl groups
GAY71_RS18670	COG1086	Polysaccharide biosynthesis protein
GAY71_RS18675	COG0489	protein tyrosine kinase activity
GAY71_RS18680	COG3944	biosynthesis protein
GAY71_RS18685	COG1396	sequence-specific DNA binding
GAY71_RS18690	COG2272	Belongs to the type-B carboxylesterase lipase family
GAY71_RS18700	COG3479	Phenolic acid decarboxylase
GAY71_RS18710	COG1794	racemase activity, acting on amino acids and derivatives
GAY71_RS18715	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GAY71_RS18720	COG1621	beta-fructofuranosidase activity
GAY71_RS18725	COG1621	beta-fructofuranosidase activity
GAY71_RS18730	COG0531	amino acid
GAY71_RS18735	COG1309	transcriptional regulator
GAY71_RS18740	COG2076	Multidrug Resistance protein
GAY71_RS18745	COG2076	Multidrug Resistance protein
GAY71_RS18755	COG0277	FAD linked oxidase domain protein
GAY71_RS18760	COG3621	Patatin-like phospholipase
GAY71_RS18770	COG0740	serine-type endopeptidase activity
GAY71_RS18775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GAY71_RS18780	COG0366	Alpha amylase catalytic
GAY71_RS18785	COG1554	hydrolase, family 65, central catalytic
GAY71_RS18790	COG5521	maltodextrose utilization protein MalA
GAY71_RS18795	COG3833	ABC-type maltose transport systems, permease component
GAY71_RS18800	COG1175	transmembrane transport
GAY71_RS18805	COG2182	Extracellular solute-binding protein
GAY71_RS18810	COG0366	Alpha amylase catalytic
GAY71_RS18815	COG1609	Transcriptional regulator
GAY71_RS18820	COG1611	Belongs to the LOG family
GAY71_RS18825	COG1694	Mazg nucleotide pyrophosphohydrolase
GAY71_RS18830	COG0659	secondary active sulfate transmembrane transporter activity
GAY71_RS18835	COG0288	reversible hydration of carbon dioxide
GAY71_RS18840	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GAY71_RS18845	COG0577	efflux transmembrane transporter activity
GAY71_RS18850	COG1136	(ABC) transporter
GAY71_RS18855	COG5002	protein histidine kinase activity
GAY71_RS18860	COG0745	RESPONSE REGULATOR receiver
GAY71_RS18870	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GAY71_RS18875	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GAY71_RS18880	COG1481	regulation of sporulation
GAY71_RS18885	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GAY71_RS18890	COG1660	Displays ATPase and GTPase activities
GAY71_RS18895	COG1051	belongs to the nudix hydrolase family
GAY71_RS18900	COG0492	ferredoxin-NADP+ reductase activity
GAY71_RS18905	COG0791	NLP P60 protein
GAY71_RS18905	COG3883	PFAM NLP P60 protein
GAY71_RS18910	COG0457	Tetratricopeptide repeat
GAY71_RS18915	COG1132	(ABC) transporter
GAY71_RS18935	COG0140	phosphoribosyl-ATP diphosphatase activity
GAY71_RS18935	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GAY71_RS18940	COG0107	imidazoleglycerol-phosphate synthase activity
GAY71_RS18945	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GAY71_RS18950	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GAY71_RS18955	COG0131	Imidazoleglycerol-phosphate dehydratase
GAY71_RS18960	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GAY71_RS18965	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GAY71_RS18970	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GAY71_RS18975	COG4990	cell redox homeostasis
GAY71_RS18980	COG5297	Belongs to the glycosyl hydrolase family 6
GAY71_RS18985	COG0110	maltose O-acetyltransferase activity
GAY71_RS18990	COG0546	phosphoglycolate phosphatase activity
GAY71_RS18995	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GAY71_RS19000	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GAY71_RS19005	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GAY71_RS19010	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GAY71_RS19015	COG0363	glucosamine-6-phosphate deaminase activity
GAY71_RS19030	COG1846	Transcriptional regulator
GAY71_RS19035	COG2124	cytochrome p450
GAY71_RS19045	COG1846	Transcriptional regulator
GAY71_RS19050	COG2814	Major facilitator Superfamily
GAY71_RS19055	COG1950	PFAM Membrane protein of
GAY71_RS19060	COG1983	PspC domain protein
GAY71_RS19065	COG3595	metallopeptidase activity
GAY71_RS19085	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GAY71_RS19090	COG0556	nucleotide-excision repair
GAY71_RS19095	COG4897	Protein conserved in bacteria
GAY71_RS19100	COG3848	Pyruvate phosphate dikinase
GAY71_RS19100	COG0574	Belongs to the PEP-utilizing enzyme family
GAY71_RS19105	COG1309	transcriptional regulator
GAY71_RS19110	COG2814	Major facilitator Superfamily
GAY71_RS19115	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GAY71_RS19125	COG3409	Peptidoglycan-binding domain 1 protein
GAY71_RS19125	COG0793	Belongs to the peptidase S41A family
GAY71_RS19130	COG2177	Part of the ABC transporter FtsEX involved in
GAY71_RS19135	COG2884	Cell division ATP-binding protein ftsE
GAY71_RS19140	COG2010	Cytochrome c
GAY71_RS19145	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GAY71_RS19155	COG0653	protein targeting
GAY71_RS19160	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GAY71_RS19175	COG1516	flagellar protein fliS
GAY71_RS19180	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GAY71_RS19185	COG1334	flagellar protein FlaG
GAY71_RS19190	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GAY71_RS19195	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GAY71_RS19200	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
GAY71_RS19210	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GAY71_RS19215	COG4786	Flagellar basal body rod
GAY71_RS19215	COG1256	bacterial-type flagellum assembly
GAY71_RS19220	COG3418	PFAM FlgN family protein
GAY71_RS19225	COG2747	anti-sigma28 factor FlgM
GAY71_RS19235	COG1040	competence protein
GAY71_RS19245	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GAY71_RS19250	COG1307	EDD domain protein, DegV family
GAY71_RS19255	COG2197	response regulator
GAY71_RS19260	COG4585	Histidine kinase
GAY71_RS19265	COG1739	Uncharacterized protein family UPF0029
GAY71_RS19270	COG1316	TRANSCRIPTIONal
GAY71_RS19275	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GAY71_RS19280	COG0438	transferase activity, transferring glycosyl groups
GAY71_RS19285	COG1215	transferase activity, transferring glycosyl groups
GAY71_RS19290	COG3206	protein involved in exopolysaccharide biosynthesis
GAY71_RS19295	COG3307	-O-antigen
GAY71_RS19300	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GAY71_RS19305	COG0297	glycogen (starch) synthase activity
GAY71_RS19305	COG0438	transferase activity, transferring glycosyl groups
GAY71_RS19310	COG2244	polysaccharide biosynthetic process
GAY71_RS19320	COG2247	cell wall binding repeat
GAY71_RS19320	COG0860	N-Acetylmuramoyl-L-alanine amidase
GAY71_RS19325	COG2247	cell wall binding repeat
GAY71_RS19325	COG2385	sporulation resulting in formation of a cellular spore
GAY71_RS19335	COG1316	TRANSCRIPTIONal
GAY71_RS19340	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GAY71_RS19345	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GAY71_RS19355	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GAY71_RS19355	COG1215	transferase activity, transferring glycosyl groups
GAY71_RS19360	COG0463	Glycosyl transferase, family 2
GAY71_RS19370	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GAY71_RS19380	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GAY71_RS19385	COG1134	teichoic acid transport
GAY71_RS19390	COG1682	transport, permease protein
GAY71_RS19395	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GAY71_RS19400	COG0438	transferase activity, transferring glycosyl groups
GAY71_RS19405	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GAY71_RS19410	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GAY71_RS19415	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GAY71_RS19425	COG4193	domain, Protein
GAY71_RS19430	COG1482	cell wall glycoprotein biosynthetic process
GAY71_RS19435	COG0697	spore germination
GAY71_RS19440	COG0814	amino acid
GAY71_RS19450	COG2814	Major facilitator Superfamily
GAY71_RS19455	COG1316	TRANSCRIPTIONal
GAY71_RS19460	COG0561	phosphatase activity
GAY71_RS19465	COG0791	NLP P60 protein
GAY71_RS19475	COG2843	Capsule synthesis protein
GAY71_RS19485	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GAY71_RS19490	COG1609	Transcriptional regulator
GAY71_RS19495	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GAY71_RS19500	COG1869	D-ribose catabolic process
GAY71_RS19505	COG1129	ABC transporter
GAY71_RS19510	COG1172	Belongs to the binding-protein-dependent transport system permease family
GAY71_RS19515	COG1879	ABC-type sugar transport system periplasmic component
GAY71_RS19530	COG2249	NAD(P)H dehydrogenase (quinone) activity
GAY71_RS19535	COG3527	Alpha-acetolactate decarboxylase
GAY71_RS19540	COG0028	Belongs to the TPP enzyme family
GAY71_RS19545	COG0583	DNA-binding transcription factor activity
GAY71_RS19550	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GAY71_RS19565	COG5337	Spore coat protein CotH
GAY71_RS19575	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GAY71_RS19585	COG0405	Gamma-glutamyltransferase
GAY71_RS19590	COG1522	sequence-specific DNA binding
GAY71_RS19595	COG2059	Chromate
GAY71_RS19600	COG2059	Chromate
GAY71_RS19610	COG0655	NAD(P)H dehydrogenase (quinone) activity
GAY71_RS19615	COG0583	DNA-binding transcription factor activity
GAY71_RS19620	COG1515	deoxyribonuclease V activity
GAY71_RS19625	COG2849	repeat protein
GAY71_RS19630	COG5444	nuclease activity
GAY71_RS19650	COG3878	Protein conserved in bacteria
GAY71_RS19655	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GAY71_RS19660	COG4464	protein tyrosine phosphatase activity
GAY71_RS19665	COG0489	protein tyrosine kinase activity
GAY71_RS19670	COG3944	biosynthesis protein
GAY71_RS19680	COG4715	Zinc finger, swim domain protein
GAY71_RS19685	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GAY71_RS19690	COG0561	phosphatase activity
GAY71_RS19700	COG0629	single-stranded DNA binding
GAY71_RS19715	COG3764	Sortase (surface protein transpeptidase)
GAY71_RS19725	COG0745	RESPONSE REGULATOR receiver
GAY71_RS19725	COG2972	Histidine kinase
GAY71_RS19730	COG1970	mechanosensitive ion channel activity
GAY71_RS19735	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GAY71_RS19740	COG0457	Tetratricopeptide repeat
GAY71_RS19745	COG4786	Flagellar basal body rod
GAY71_RS19750	COG4786	Flagellar basal body rod
GAY71_RS19755	COG1077	Cell shape determining protein MreB Mrl
GAY71_RS19760	COG1609	Transcriptional regulator
GAY71_RS19770	COG1846	Transcriptional regulator
GAY71_RS19775	COG2814	Major facilitator Superfamily
GAY71_RS19780	COG3420	alginic acid biosynthetic process
GAY71_RS19785	COG1953	Uracil, thiamine, allantoin
GAY71_RS19790	COG0477	Major facilitator Superfamily
GAY71_RS19795	COG1335	isochorismatase
GAY71_RS19805	COG0004	ammonium transporteR
GAY71_RS19810	COG0347	Belongs to the P(II) protein family
GAY71_RS19815	COG0671	phosphoesterase, PA-phosphatase related
GAY71_RS19825	COG0739	heme binding
GAY71_RS19830	COG1247	-acetyltransferase
GAY71_RS19850	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GAY71_RS19855	COG0789	Transcriptional regulator
GAY71_RS19865	COG2910	NAD(P)H-binding
GAY71_RS19870	COG1959	2 iron, 2 sulfur cluster binding
GAY71_RS19875	COG0804	urea catabolic process
GAY71_RS19880	COG0832	Belongs to the urease beta subunit family
GAY71_RS19885	COG0831	urea catabolic process
GAY71_RS19900	COG3237	CsbD-like
GAY71_RS19905	COG1994	Peptidase M50
GAY71_RS19910	COG0457	Tetratricopeptide repeat
GAY71_RS19915	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GAY71_RS19920	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GAY71_RS19930	COG2304	oxidoreductase activity
GAY71_RS19940	COG2304	oxidoreductase activity
GAY71_RS19945	COG2385	sporulation resulting in formation of a cellular spore
GAY71_RS19950	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GAY71_RS19960	COG4836	Membrane
GAY71_RS19970	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GAY71_RS19975	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GAY71_RS19980	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GAY71_RS19985	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GAY71_RS19990	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GAY71_RS19995	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GAY71_RS20000	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GAY71_RS20005	COG0356	it plays a direct role in the translocation of protons across the membrane
GAY71_RS20015	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GAY71_RS20020	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GAY71_RS20025	COG4475	Protein of unknown function (DUF436)
GAY71_RS20030	COG0698	ribose 5-phosphate isomerase
GAY71_RS20035	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GAY71_RS20040	COG1971	Probably functions as a manganese efflux pump
GAY71_RS20045	COG0009	L-threonylcarbamoyladenylate synthase
GAY71_RS20050	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GAY71_RS20070	COG2890	protein-(glutamine-N5) methyltransferase activity
GAY71_RS20075	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GAY71_RS20080	COG0346	lactoylglutathione lyase activity
GAY71_RS20085	COG0789	Transcriptional regulator
GAY71_RS20090	COG0679	Auxin Efflux Carrier
GAY71_RS20095	COG0281	malic enzyme
GAY71_RS20100	COG1435	thymidine kinase activity
GAY71_RS20105	COG0254	rRNA binding
GAY71_RS20110	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GAY71_RS20120	COG1494	fructose-1,6-bisphosphatase
GAY71_RS20125	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GAY71_RS20130	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GAY71_RS20135	COG0191	fructose-bisphosphate aldolase activity
GAY71_RS20140	COG2204	response regulator
GAY71_RS20145	COG4821	SIS domain
GAY71_RS20150	COG0504	CTP synthase activity
GAY71_RS20155	COG3343	RNA polymerase activity
GAY71_RS20160	COG1960	acyl-CoA dehydrogenase activity
GAY71_RS20165	COG2181	nitrate reductase activity
GAY71_RS20165	COG0247	lactate metabolic process
GAY71_RS20175	COG4294	response to UV
GAY71_RS20185	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GAY71_RS20190	COG1132	(ABC) transporter
GAY71_RS20195	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GAY71_RS20205	COG2181	nitrate reductase activity
GAY71_RS20210	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GAY71_RS20215	COG1140	nitrate reductase beta subunit
GAY71_RS20220	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GAY71_RS20225	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GAY71_RS20235	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GAY71_RS20240	COG2223	nitrite transmembrane transporter activity
GAY71_RS20245	COG0018	arginyl-trna synthetase
GAY71_RS20250	COG4506	Protein conserved in bacteria
GAY71_RS20265	COG0535	radical SAM domain protein
GAY71_RS20275	COG1131	(ABC) transporter
GAY71_RS20280	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GAY71_RS20285	COG0612	Peptidase, M16
GAY71_RS20290	COG0612	Peptidase, M16
GAY71_RS20300	COG3391	amine dehydrogenase activity
GAY71_RS20305	COG3391	amine dehydrogenase activity
GAY71_RS20315	COG0457	Tetratricopeptide repeat
GAY71_RS20325	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GAY71_RS20330	COG0010	Belongs to the arginase family
GAY71_RS20335	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GAY71_RS20340	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GAY71_RS20350	COG1994	Peptidase M50
GAY71_RS20355	COG1942	4-Oxalocrotonate Tautomerase
GAY71_RS20360	COG1846	Transcriptional regulator
GAY71_RS20365	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GAY71_RS20370	COG0477	Major facilitator Superfamily
GAY71_RS20375	COG1959	2 iron, 2 sulfur cluster binding
GAY71_RS20380	COG3465	dGTPase activity
GAY71_RS20385	COG1078	dGTPase activity
GAY71_RS20390	COG4844	belongs to the
GAY71_RS20400	COG0697	spore germination
GAY71_RS20405	COG0095	Lipoate-protein ligase
GAY71_RS20410	COG0583	DNA-binding transcription factor activity
GAY71_RS20415	COG0280	phosphate acetyltransferase
GAY71_RS20425	COG1028	Short-chain dehydrogenase reductase Sdr
GAY71_RS20430	COG0436	Aminotransferase
GAY71_RS20435	COG2814	Major facilitator Superfamily
GAY71_RS20440	COG0151	Belongs to the GarS family
GAY71_RS20445	COG1028	Short-chain dehydrogenase reductase Sdr
GAY71_RS20450	COG1917	Cupin 2, conserved barrel domain protein
GAY71_RS20455	COG0077	Prephenate dehydratase
GAY71_RS20460	COG2814	Major facilitator Superfamily
GAY71_RS20465	COG0833	amino acid
GAY71_RS20470	COG4187	Peptidase family M20/M25/M40
GAY71_RS20475	COG1012	belongs to the aldehyde dehydrogenase family
GAY71_RS20480	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GAY71_RS20490	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
GAY71_RS20495	COG1091	dTDP-4-dehydrorhamnose reductase activity
GAY71_RS20500	COG1088	dTDP-glucose 4,6-dehydratase activity
GAY71_RS20505	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GAY71_RS20510	COG3980	spore coat polysaccharide biosynthesis protein
GAY71_RS20515	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
GAY71_RS20520	COG2089	acid synthase
GAY71_RS20525	COG0456	acetyltransferase
GAY71_RS20530	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GAY71_RS20535	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GAY71_RS20540	COG0463	Glycosyl transferase, family 2
GAY71_RS20550	COG2363	Small membrane protein
GAY71_RS20565	COG1012	belongs to the aldehyde dehydrogenase family
GAY71_RS20570	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GAY71_RS20575	COG1216	Glycosyl transferase, family 2
GAY71_RS20590	COG1695	Transcriptional regulator
GAY71_RS20595	COG0351	phosphomethylpyrimidine kinase
GAY71_RS20605	COG1621	beta-fructofuranosidase activity
GAY71_RS20610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GAY71_RS20610	COG1263	PTS System
GAY71_RS20615	COG2116	formate transmembrane transporter activity
GAY71_RS20620	COG3711	transcriptional antiterminator
GAY71_RS20630	COG1404	Belongs to the peptidase S8 family
GAY71_RS20635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GAY71_RS20640	COG0778	Nitroreductase
GAY71_RS20645	COG0772	Belongs to the SEDS family
GAY71_RS20655	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GAY71_RS20660	COG1845	cytochrome c oxidase, subunit III
GAY71_RS20665	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GAY71_RS20670	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GAY71_RS20675	COG2261	transglycosylase associated protein
GAY71_RS20680	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GAY71_RS20685	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GAY71_RS20690	COG2246	polysaccharide biosynthetic process
GAY71_RS20695	COG1309	transcriptional regulator
GAY71_RS20705	COG3162	membrane
GAY71_RS20710	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GAY71_RS20715	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GAY71_RS20720	COG2837	iron assimilation
GAY71_RS20725	COG2822	iron ion transport
GAY71_RS20730	COG0672	)-iron permease
GAY71_RS20735	COG0352	thiamine-phosphate diphosphorylase activity
GAY71_RS20740	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GAY71_RS20745	COG0583	DNA-binding transcription factor activity
GAY71_RS20750	COG1380	Effector of murein hydrolase LrgA
GAY71_RS20755	COG1346	cytolysis
GAY71_RS20760	COG2814	Major facilitator Superfamily
GAY71_RS20765	COG4895	conserved protein (DUF2196)
GAY71_RS20770	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GAY71_RS20775	COG0346	lactoylglutathione lyase activity
GAY71_RS20785	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GAY71_RS20790	COG1404	Belongs to the peptidase S8 family
GAY71_RS20795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GAY71_RS20795	COG1263	PTS System
GAY71_RS20800	COG3711	transcriptional antiterminator
GAY71_RS20805	COG1442	glycosyl transferase family 8
GAY71_RS20810	COG5522	Integral membrane protein (intg_mem_TP0381)
GAY71_RS20815	COG1846	Transcriptional regulator
GAY71_RS20820	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GAY71_RS20825	COG2234	aminopeptidase activity
GAY71_RS20830	COG2357	RelA SpoT domain protein
GAY71_RS20835	COG1575	Belongs to the MenA family. Type 1 subfamily
GAY71_RS20850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GAY71_RS20855	COG1696	Membrane protein involved in D-alanine export
GAY71_RS20860	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GAY71_RS20865	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GAY71_RS20870	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
GAY71_RS20875	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GAY71_RS20880	COG1486	melibiose metabolic process
GAY71_RS20885	COG1447	Phosphotransferase system cellobiose-specific component IIA
GAY71_RS20890	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GAY71_RS20895	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GAY71_RS20900	COG3711	transcriptional antiterminator
GAY71_RS20900	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GAY71_RS20910	COG2094	Belongs to the DNA glycosylase MPG family
GAY71_RS20915	COG0753	catalase activity
GAY71_RS20920	COG2814	Major facilitator Superfamily
GAY71_RS20925	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GAY71_RS20930	COG1131	(ABC) transporter
GAY71_RS20950	COG1595	DNA-templated transcription, initiation
GAY71_RS20955	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GAY71_RS20960	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GAY71_RS20965	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GAY71_RS20970	COG4988	ABC transporter
GAY71_RS20975	COG1294	oxidase, subunit
GAY71_RS20980	COG1271	oxidase subunit
GAY71_RS20985	COG3493	citrate carrier protein
GAY71_RS20990	COG0501	Belongs to the peptidase M48B family
GAY71_RS21000	COG0726	polysaccharide deacetylase
GAY71_RS21005	COG3842	ATPase activity
GAY71_RS21010	COG2508	Transcriptional regulator
GAY71_RS21015	COG1012	belongs to the aldehyde dehydrogenase family
GAY71_RS21020	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GAY71_RS21030	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GAY71_RS21035	COG1881	PFAM PEBP family protein
GAY71_RS21040	COG0583	DNA-binding transcription factor activity
GAY71_RS21050	COG4585	Histidine kinase
GAY71_RS21055	COG2197	response regulator
GAY71_RS21060	COG2195	Cleaves the N-terminal amino acid of tripeptides
GAY71_RS21070	COG4894	glucomannan catabolic process
GAY71_RS21075	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GAY71_RS21080	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GAY71_RS21085	COG1028	Short-chain dehydrogenase reductase Sdr
GAY71_RS21090	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GAY71_RS21095	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GAY71_RS21100	COG2610	gluconate transmembrane transporter activity
GAY71_RS21105	COG0500	methyltransferase
GAY71_RS21110	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GAY71_RS21125	COG0753	catalase activity
GAY71_RS21125	COG0693	protein deglycase activity
GAY71_RS21130	COG2851	Citrate transporter
GAY71_RS21135	COG2273	Hydrolase Family 16
GAY71_RS21140	COG3711	transcriptional antiterminator
GAY71_RS21150	COG2270	Major facilitator Superfamily
GAY71_RS21155	COG0513	Belongs to the DEAD box helicase family
GAY71_RS21160	COG2755	lipolytic protein G-D-S-L family
GAY71_RS21160	COG3401	FG-GAP repeat protein
GAY71_RS21215	COG3209	COG3209 Rhs family protein
GAY71_RS21220	COG0697	spore germination
GAY71_RS21225	COG0589	response to stress
GAY71_RS21230	COG2723	6-phospho-beta-galactosidase activity
GAY71_RS21235	COG1263	PTS System
GAY71_RS21235	COG2190	(PTS) system
GAY71_RS21235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GAY71_RS21250	COG5444	nuclease activity
GAY71_RS21265	COG3507	Belongs to the glycosyl hydrolase 43 family
GAY71_RS21280	COG2986	histidine ammonia-lyase
GAY71_RS21285	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GAY71_RS21290	COG1228	amidohydrolase
GAY71_RS21295	COG0010	Belongs to the arginase family
GAY71_RS21300	COG0833	amino acid
GAY71_RS21305	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GAY71_RS21310	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GAY71_RS21315	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GAY71_RS21320	COG2390	Transcriptional regulator
GAY71_RS21330	COG3192	ethanolamine utilization protein
GAY71_RS21335	COG2079	MmgE PrpD family protein
GAY71_RS21345	COG1126	abc transporter atp-binding protein
GAY71_RS21350	COG0765	amino acid transport
GAY71_RS21355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GAY71_RS21375	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
GAY71_RS21380	COG0561	phosphatase activity
GAY71_RS21410	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GAY71_RS21415	COG5294	Protein conserved in bacteria
GAY71_RS21420	COG0577	efflux transmembrane transporter activity
GAY71_RS21425	COG1136	(ABC) transporter
GAY71_RS21430	COG2205	protein histidine kinase activity
GAY71_RS21435	COG0745	RESPONSE REGULATOR receiver
GAY71_RS21440	COG0191	fructose-bisphosphate aldolase activity
GAY71_RS21445	COG1082	Xylose isomerase domain protein TIM barrel
GAY71_RS21450	COG1082	Xylose isomerase domain protein TIM barrel
GAY71_RS21455	COG0673	inositol 2-dehydrogenase activity
GAY71_RS21460	COG2814	Major facilitator Superfamily
GAY71_RS21465	COG1082	Xylose isomerase domain protein TIM barrel
GAY71_RS21470	COG3962	Belongs to the TPP enzyme family
GAY71_RS21475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GAY71_RS21480	COG3718	enzyme involved in inositol metabolism
GAY71_RS21485	COG1012	belongs to the aldehyde dehydrogenase family
GAY71_RS21490	COG1349	DNA-binding transcription factor activity
GAY71_RS21495	COG0667	Aldo Keto reductase
GAY71_RS21510	COG2814	Major facilitator Superfamily
GAY71_RS21515	COG0326	Molecular chaperone. Has ATPase activity
GAY71_RS21525	COG1028	Short-chain dehydrogenase reductase Sdr
GAY71_RS21530	COG1309	transcriptional regulator
GAY71_RS21535	COG1012	belongs to the aldehyde dehydrogenase family
GAY71_RS21540	COG0456	acetyltransferase
GAY71_RS21545	COG2850	peptidyl-arginine hydroxylation
GAY71_RS21550	COG2226	methyltransferase
GAY71_RS21565	COG0367	asparagine synthase
GAY71_RS21570	COG2814	Major facilitator Superfamily
GAY71_RS21575	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GAY71_RS21585	COG1714	RDD family
GAY71_RS21590	COG2311	Membrane
GAY71_RS21595	COG1917	Cupin 2, conserved barrel domain protein
GAY71_RS21600	COG1309	transcriptional regulator
GAY71_RS21605	COG1028	Short-chain dehydrogenase reductase Sdr
GAY71_RS21610	COG1846	Transcriptional regulator
GAY71_RS21615	COG1380	Effector of murein hydrolase LrgA
GAY71_RS21620	COG1346	cytolysis
GAY71_RS21625	COG5039	Polysaccharide pyruvyl transferase
GAY71_RS21630	COG1929	Belongs to the glycerate kinase type-1 family
GAY71_RS21635	COG1802	Transcriptional regulator
GAY71_RS21640	COG1070	Carbohydrate kinase
GAY71_RS21645	COG2610	gluconate transmembrane transporter activity
GAY71_RS21650	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GAY71_RS21655	COG0450	alkyl hydroperoxide reductase
GAY71_RS21660	COG3634	alkyl hydroperoxide reductase activity
GAY71_RS21665	COG2723	6-phospho-beta-galactosidase activity
GAY71_RS21670	COG2190	(PTS) system
GAY71_RS21680	COG2188	Transcriptional regulator
GAY71_RS21695	COG1131	(ABC) transporter
GAY71_RS21700	COG1994	Peptidase M50
GAY71_RS21705	COG0535	radical SAM domain protein
GAY71_RS21715	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
GAY71_RS21720	COG5293	efflux transmembrane transporter activity
GAY71_RS21730	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GAY71_RS21735	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GAY71_RS21750	COG1063	alcohol dehydrogenase
GAY71_RS21770	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GAY71_RS21775	COG0456	acetyltransferase
GAY71_RS21780	COG0457	Tetratricopeptide repeat
GAY71_RS21790	COG0010	Belongs to the arginase family
GAY71_RS21795	COG0833	amino acid
GAY71_RS21800	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GAY71_RS21805	COG3829	transcription factor binding
GAY71_RS21820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GAY71_RS21825	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GAY71_RS21830	COG4853	Protein conserved in bacteria
GAY71_RS21835	COG4863	YycH protein
GAY71_RS21840	COG5002	protein histidine kinase activity
GAY71_RS21845	COG0745	RESPONSE REGULATOR receiver
GAY71_RS21875	COG0346	lactoylglutathione lyase activity
GAY71_RS21880	COG0305	Participates in initiation and elongation during chromosome replication
GAY71_RS21895	COG3093	addiction module antidote protein HigA
GAY71_RS21900	COG2807	transmembrane transport
GAY71_RS21905	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GAY71_RS21910	COG0359	binds to the 23S rRNA
GAY71_RS21915	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
GAY71_RS21920	COG4241	membrane
GAY71_RS21930	COG5577	PFAM Coat F domain
GAY71_RS21935	COG1733	regulation of RNA biosynthetic process
GAY71_RS21940	COG1227	inorganic diphosphatase activity
GAY71_RS21955	COG2271	Major facilitator Superfamily
GAY71_RS21990	COG1131	(ABC) transporter
GAY71_RS22005	COG4319	ketosteroid isomerase
GAY71_RS22010	COG1357	PFAM Pentapeptide repeats (8 copies)
GAY71_RS22015	COG2814	Major facilitator Superfamily
GAY71_RS22020	COG0583	DNA-binding transcription factor activity
GAY71_RS22025	COG2153	protein acetylation
GAY71_RS22035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GAY71_RS22040	COG1846	Transcriptional regulator
GAY71_RS22045	COG2153	protein acetylation
GAY71_RS22050	COG2364	Membrane
GAY71_RS22055	COG0456	acetyltransferase
GAY71_RS22060	COG2315	Protein conserved in bacteria
GAY71_RS22065	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GAY71_RS22075	COG2814	Major facilitator Superfamily
GAY71_RS22085	COG1331	Highly conserved protein containing a thioredoxin domain
GAY71_RS22090	COG0789	Transcriptional regulator
GAY71_RS22095	COG0697	spore germination
GAY71_RS22100	COG1331	Highly conserved protein containing a thioredoxin domain
GAY71_RS22105	COG1266	CAAX protease self-immunity
GAY71_RS22110	COG2814	Major facilitator Superfamily
GAY71_RS22110	COG0477	Major facilitator Superfamily
GAY71_RS22115	COG0110	maltose O-acetyltransferase activity
GAY71_RS22120	COG0346	lactoylglutathione lyase activity
GAY71_RS22125	COG1609	Transcriptional regulator
GAY71_RS22130	COG0708	Exodeoxyribonuclease III
GAY71_RS22135	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GAY71_RS22140	COG0629	single-stranded DNA binding
GAY71_RS22145	COG0360	Binds together with S18 to 16S ribosomal RNA
GAY71_RS22150	COG0012	GTP binding
GAY71_RS22155	COG0243	molybdopterin cofactor binding
GAY71_RS22160	COG4481	Protein conserved in bacteria
GAY71_RS22165	COG3949	Membrane
GAY71_RS22175	COG1475	DNA binding
GAY71_RS22180	COG1192	Involved in chromosome partitioning
GAY71_RS22190	COG1475	DNA binding
GAY71_RS22195	COG0357	Ribosomal RNA small subunit methyltransferase G
GAY71_RS22200	COG0445	tRNA wobble uridine modification
GAY71_RS22205	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GAY71_RS22210	COG1847	R3H domain protein
GAY71_RS22215	COG0706	membrane insertase activity
GAY71_RS22220	COG0594	ribonuclease P activity
GAY71_RS22225	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GAY71_RS22235	COG1547	Domain of unknown function (DUF309)
GAY71_RS22240	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GAY71_RS22245	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GAY71_RS22275	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GAY71_RS22285	COG1192	Involved in chromosome partitioning
GAY71_RS22335	COG1192	Involved in chromosome partitioning
GAY71_RS22385	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
GAY71_RS22395	COG0681	Belongs to the peptidase S26 family
GAY71_RS22405	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GAY71_RS22405	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GAY71_RS22410	COG0307	riboflavin synthase, alpha
GAY71_RS22415	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GAY71_RS22415	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GAY71_RS22420	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GAY71_RS22425	COG0456	acetyltransferase
GAY71_RS22430	COG1547	Domain of unknown function (DUF309)
GAY71_RS22460	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GAY71_RS22460	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GAY71_RS22465	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity