locus-tag	class	description
GII77_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GII77_RS00010	COG0592	DNA-directed DNA polymerase activity
GII77_RS00015	COG2501	S4 domain
GII77_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GII77_RS00030	COG0187	DNA topoisomerase II activity
GII77_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GII77_RS00070	COG0517	IMP dehydrogenase activity
GII77_RS00070	COG0516	GMP reductase activity
GII77_RS00075	COG1686	Belongs to the peptidase S11 family
GII77_RS00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GII77_RS00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GII77_RS00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GII77_RS00100	COG1428	Deoxynucleoside kinase
GII77_RS00105	COG1428	Deoxynucleoside kinase
GII77_RS00110	COG3858	chitin binding
GII77_RS00110	COG1388	LysM domain
GII77_RS00115	COG1335	isochorismatase
GII77_RS00120	COG0590	tRNA wobble adenosine to inosine editing
GII77_RS00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GII77_RS00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GII77_RS00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GII77_RS00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
GII77_RS00190	COG3853	Toxic anion resistance protein (TelA)
GII77_RS00195	COG1982	Orn Lys Arg decarboxylase major
GII77_RS00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GII77_RS00205	COG3870	Protein conserved in bacteria
GII77_RS00210	COG1728	Protein conserved in bacteria
GII77_RS00215	COG0470	DNA polymerase III
GII77_RS00220	COG1774	PSP1 C-terminal conserved region
GII77_RS00225	COG4467	Involved in initiation control of chromosome replication
GII77_RS00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GII77_RS00235	COG2827	Endonuclease containing a URI domain
GII77_RS00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GII77_RS00245	COG2002	toxin-antitoxin pair type II binding
GII77_RS00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII77_RS00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII77_RS00255	COG0084	hydrolase, TatD family'
GII77_RS00260	COG3583	domain protein
GII77_RS00260	COG3584	3D domain protein
GII77_RS00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GII77_RS00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GII77_RS00280	COG4466	Protein conserved in bacteria
GII77_RS00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GII77_RS00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GII77_RS00300	COG0251	oxidation-reduction process
GII77_RS00305	COG2088	sporulation resulting in formation of a cellular spore
GII77_RS00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GII77_RS00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GII77_RS00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GII77_RS00325	COG0193	aminoacyl-tRNA hydrolase activity
GII77_RS00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GII77_RS00340	COG2002	toxin-antitoxin pair type II binding
GII77_RS00345	COG2244	polysaccharide biosynthetic process
GII77_RS00350	COG3956	TIGRFAM MazG family protein
GII77_RS00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GII77_RS00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GII77_RS00375	COG1098	S1 RNA binding domain
GII77_RS00390	COG2208	phosphoserine phosphatase activity
GII77_RS00395	COG2304	oxidoreductase activity
GII77_RS00400	COG0515	serine threonine protein kinase
GII77_RS00405	COG0037	tRNA processing
GII77_RS00410	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GII77_RS00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GII77_RS00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GII77_RS00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GII77_RS00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GII77_RS00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GII77_RS00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GII77_RS00445	COG0512	Glutamine amidotransferase of anthranilate synthase
GII77_RS00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII77_RS00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GII77_RS00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GII77_RS00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GII77_RS00470	COG1396	sequence-specific DNA binding
GII77_RS00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GII77_RS00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GII77_RS00560	COG4463	regulation of RNA biosynthetic process
GII77_RS00565	COG3880	PFAM UvrB UvrC protein
GII77_RS00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
GII77_RS00575	COG0542	response to heat
GII77_RS00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GII77_RS00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
GII77_RS00590	COG4956	integral membrane protein (PIN domain superfamily)
GII77_RS00595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GII77_RS00600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GII77_RS00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GII77_RS00610	COG1045	serine acetyltransferase
GII77_RS00615	COG0215	cysteine-tRNA ligase activity
GII77_RS00620	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GII77_RS00625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GII77_RS00630	COG3688	RNA-binding protein containing a PIN domain
GII77_RS00635	COG1595	DNA-templated transcription, initiation
GII77_RS00645	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GII77_RS00650	COG0250	Participates in transcription elongation, termination and antitermination
GII77_RS00660	COG0081	regulation of translation
GII77_RS00665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GII77_RS00675	COG2813	Specifically methylates the guanine in position
GII77_RS00680	COG0085	RNA polymerase activity
GII77_RS00685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GII77_RS00690	COG1358	cellular component organization or biogenesis
GII77_RS00695	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GII77_RS00700	COG0049	tRNA binding
GII77_RS00705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GII77_RS00710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GII77_RS00715	COG0596	Alpha beta hydrolase
GII77_RS00725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GII77_RS00730	COG0088	Forms part of the polypeptide exit tunnel
GII77_RS00740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GII77_RS00755	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GII77_RS00760	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GII77_RS00770	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GII77_RS00775	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GII77_RS00785	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GII77_RS00795	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GII77_RS00800	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GII77_RS00805	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GII77_RS00810	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GII77_RS00820	COG0200	Binds to the 23S rRNA
GII77_RS00825	COG0201	protein transport
GII77_RS00830	COG0563	adenylate kinase activity
GII77_RS00835	COG0024	Methionine aminopeptidase
GII77_RS00840	COG2163	COG2163 Ribosomal protein L14E L6E L27E
GII77_RS00850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GII77_RS00855	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GII77_RS00860	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GII77_RS00865	COG0202	RNA polymerase activity
GII77_RS00870	COG0203	ribosomal protein L17
GII77_RS00875	COG1122	ATPase activity
GII77_RS00880	COG1122	ATPase activity
GII77_RS00885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GII77_RS00890	COG0101	tRNA pseudouridine synthase activity
GII77_RS00895	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GII77_RS00900	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GII77_RS00905	COG2226	methyltransferase
GII77_RS00915	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII77_RS00920	COG0489	protein tyrosine kinase activity
GII77_RS00930	COG2194	sulfuric ester hydrolase activity
GII77_RS00935	COG0726	polysaccharide deacetylase
GII77_RS01015	COG0659	secondary active sulfate transmembrane transporter activity
GII77_RS01020	COG0385	Bile acid
GII77_RS01025	COG2819	hydrolase of the alpha beta superfamily
GII77_RS01030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII77_RS01035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII77_RS01040	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII77_RS01045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII77_RS01045	COG2207	Transcriptional regulator
GII77_RS01050	COG3876	Protein conserved in bacteria
GII77_RS01055	COG1472	Belongs to the glycosyl hydrolase 3 family
GII77_RS01060	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GII77_RS01065	COG1263	PTS System
GII77_RS01065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII77_RS01070	COG1737	Transcriptional regulator
GII77_RS01075	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GII77_RS01080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII77_RS01085	COG1683	Conserved Protein
GII77_RS01115	COG1595	DNA-templated transcription, initiation
GII77_RS01120	COG5662	AntiSigma factor
GII77_RS01125	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GII77_RS01130	COG4856	YbbR-like protein
GII77_RS01135	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GII77_RS01145	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GII77_RS01155	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GII77_RS01160	COG2169	Transcriptional regulator
GII77_RS01165	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GII77_RS01170	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GII77_RS01175	COG3002	Belongs to the UPF0753 family
GII77_RS01180	COG0288	reversible hydration of carbon dioxide
GII77_RS01190	COG5609	conserved protein (DUF2294)
GII77_RS01195	COG0640	Transcriptional regulator
GII77_RS01200	COG2814	Major facilitator Superfamily
GII77_RS01205	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GII77_RS01215	COG0535	radical SAM domain protein
GII77_RS01220	COG1266	CAAX protease self-immunity
GII77_RS01225	COG1131	(ABC) transporter
GII77_RS01235	COG1413	lyase activity
GII77_RS01240	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII77_RS01245	COG0596	Alpha beta hydrolase
GII77_RS01250	COG0745	RESPONSE REGULATOR receiver
GII77_RS01255	COG0642	Histidine kinase
GII77_RS01265	COG0515	serine threonine protein kinase
GII77_RS01280	COG1113	amino acid transport
GII77_RS01295	COG2602	Beta-lactamase
GII77_RS01300	COG2124	cytochrome p450
GII77_RS01310	COG0531	amino acid
GII77_RS01315	COG0584	glycerophosphoryl diester phosphodiesterase
GII77_RS01320	COG2271	Major facilitator Superfamily
GII77_RS01330	COG1846	Transcriptional regulator
GII77_RS01330	COG0456	acetyltransferase
GII77_RS01335	COG2271	Major facilitator Superfamily
GII77_RS01345	COG3409	Peptidoglycan-binding domain 1 protein
GII77_RS01350	COG0697	spore germination
GII77_RS01355	COG2207	Transcriptional regulator
GII77_RS01355	COG1917	Cupin 2, conserved barrel domain protein
GII77_RS01360	COG1397	ADP-ribosylglycohydrolase
GII77_RS01365	COG5444	nuclease activity
GII77_RS01370	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GII77_RS01375	COG3591	Belongs to the peptidase S1B family
GII77_RS01385	COG0596	Alpha beta hydrolase
GII77_RS01390	COG1183	phosphatidylcholine synthase activity
GII77_RS01395	COG0586	Pfam SNARE associated Golgi protein
GII77_RS01400	COG0688	phosphatidylethanolamine metabolic process
GII77_RS01410	COG2312	Erythromycin esterase
GII77_RS01415	COG1054	Belongs to the UPF0176 family
GII77_RS01420	COG1301	dicarboxylic acid transport
GII77_RS01425	COG1263	PTS System
GII77_RS01425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII77_RS01425	COG2190	(PTS) system
GII77_RS01430	COG0363	glucosamine-6-phosphate deaminase activity
GII77_RS01435	COG2188	Transcriptional regulator
GII77_RS01445	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII77_RS01450	COG0833	amino acid
GII77_RS01455	COG2040	homocysteine
GII77_RS01465	COG1115	amino acid carrier protein
GII77_RS01470	COG2066	Belongs to the glutaminase family
GII77_RS01475	COG4191	Histidine kinase
GII77_RS01480	COG0784	Response regulator, receiver
GII77_RS01485	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GII77_RS01490	COG1012	belongs to the aldehyde dehydrogenase family
GII77_RS01495	COG2271	Major facilitator Superfamily
GII77_RS01500	COG4948	Mandelate Racemase Muconate Lactonizing
GII77_RS01505	COG2186	Transcriptional regulator
GII77_RS01510	COG2721	sulfolactate sulfo-lyase activity
GII77_RS01515	COG3173	Aminoglycoside phosphotransferase
GII77_RS01525	COG0697	spore germination
GII77_RS01530	COG0745	RESPONSE REGULATOR receiver
GII77_RS01535	COG2205	protein histidine kinase activity
GII77_RS01540	COG1131	(ABC) transporter
GII77_RS01560	COG3773	Cell wall hydrolase
GII77_RS01565	COG2304	oxidoreductase activity
GII77_RS01575	COG3540	Alkaline phosphatase
GII77_RS01580	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GII77_RS01585	COG0805	protein transport
GII77_RS01590	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GII77_RS01595	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GII77_RS01600	COG0477	Major facilitator Superfamily
GII77_RS01605	COG1309	transcriptional regulator
GII77_RS01610	COG0252	asparaginase activity
GII77_RS01615	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GII77_RS01620	COG1714	RDD family
GII77_RS01625	COG3012	SEC-C Motif Domain Protein
GII77_RS01625	COG1405	negative regulation of cell septum assembly
GII77_RS01630	COG3290	protein histidine kinase activity
GII77_RS01635	COG3279	Response regulator of the LytR AlgR family
GII77_RS01640	COG4555	ABC transporter
GII77_RS01645	COG1668	transmembrane transport
GII77_RS01650	COG0667	Aldo Keto reductase
GII77_RS01665	COG1595	DNA-templated transcription, initiation
GII77_RS01670	COG1595	DNA-templated transcription, initiation
GII77_RS01675	COG1876	peptidase activity
GII77_RS01680	COG0457	Tetratricopeptide repeat
GII77_RS01685	COG1028	Short-chain dehydrogenase reductase Sdr
GII77_RS01690	COG0366	Alpha amylase catalytic
GII77_RS01695	COG0803	Belongs to the bacterial solute-binding protein 9 family
GII77_RS01700	COG1121	(ABC) transporter
GII77_RS01705	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GII77_RS01710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII77_RS01715	COG2310	stress, protein
GII77_RS01720	COG2310	stress, protein
GII77_RS01725	COG2310	stress, protein
GII77_RS01730	COG0861	Integral membrane protein TerC family
GII77_RS01740	COG3853	Toxic anion resistance protein (TelA)
GII77_RS01745	COG0477	Major facilitator Superfamily
GII77_RS01750	COG2814	Major facilitator Superfamily
GII77_RS01755	COG0640	Transcriptional regulator
GII77_RS01760	COG4175	Glycine betaine
GII77_RS01760	COG0517	IMP dehydrogenase activity
GII77_RS01765	COG4176	ABC-type proline glycine betaine transport system permease component
GII77_RS01770	COG2113	Glycine betaine
GII77_RS01775	COG1473	amidohydrolase
GII77_RS01780	COG1288	antiporter activity
GII77_RS01815	COG0039	L-malate dehydrogenase activity
GII77_RS01820	COG1620	l-lactate permease
GII77_RS01825	COG2814	Major facilitator Superfamily
GII77_RS01830	COG1846	Transcriptional regulator
GII77_RS01835	COG1280	lysine exporter protein (LysE YggA)
GII77_RS01840	COG3403	YqcI/YcgG family
GII77_RS01845	COG1113	amino acid transport
GII77_RS01850	COG3665	Urea carboxylase-associated protein
GII77_RS01855	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GII77_RS01860	COG1660	Displays ATPase and GTPase activities
GII77_RS01865	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GII77_RS01870	COG2226	methyltransferase
GII77_RS01875	COG0583	DNA-binding transcription factor activity
GII77_RS01880	COG3458	cephalosporin-C deacetylase activity
GII77_RS01885	COG3541	Predicted nucleotidyltransferase
GII77_RS01890	COG0506	proline dehydrogenase activity
GII77_RS01895	COG1012	belongs to the aldehyde dehydrogenase family
GII77_RS01900	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII77_RS01905	COG2508	Transcriptional regulator
GII77_RS01910	COG3689	TIGRFAM TIGR03943 family protein
GII77_RS01915	COG0701	Predicted permease
GII77_RS01920	COG2267	carboxylic ester hydrolase activity
GII77_RS01925	COG0492	ferredoxin-NADP+ reductase activity
GII77_RS01930	COG1587	Uroporphyrinogen-III synthase
GII77_RS01930	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GII77_RS01935	COG2146	nitrite reductase [NAD(P)H] activity
GII77_RS01940	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GII77_RS01945	COG0243	molybdopterin cofactor binding
GII77_RS01950	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GII77_RS01955	COG2223	nitrite transmembrane transporter activity
GII77_RS01960	COG1469	GTP cyclohydrolase I activity
GII77_RS01965	COG1376	ErfK ybiS ycfS ynhG family protein
GII77_RS01980	COG0523	cobalamin synthesis protein
GII77_RS01985	COG0765	amino acid transport
GII77_RS01990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII77_RS02010	COG1846	Transcriptional regulator
GII77_RS02025	COG2723	6-phospho-beta-galactosidase activity
GII77_RS02035	COG3209	COG3209 Rhs family protein
GII77_RS02040	COG0840	transmembrane signaling receptor activity
GII77_RS02040	COG3290	protein histidine kinase activity
GII77_RS02045	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GII77_RS02050	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
GII77_RS02055	COG1733	regulation of RNA biosynthetic process
GII77_RS02060	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII77_RS02065	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII77_RS02070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII77_RS02075	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
GII77_RS02080	COG2814	Major facilitator Superfamily
GII77_RS02090	COG0697	spore germination
GII77_RS02095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII77_RS02105	COG2364	Membrane
GII77_RS02110	COG1126	abc transporter atp-binding protein
GII77_RS02115	COG0765	amino acid transport
GII77_RS02120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII77_RS02125	COG0583	DNA-binding transcription factor activity
GII77_RS02130	COG0163	prenyltransferase activity
GII77_RS02135	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GII77_RS02150	COG0596	Alpha beta hydrolase
GII77_RS02155	COG3104	oligopeptide transport
GII77_RS02160	COG5434	Belongs to the glycosyl hydrolase 28 family
GII77_RS02170	COG0697	spore germination
GII77_RS02180	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GII77_RS02185	COG1136	(ABC) transporter
GII77_RS02190	COG0577	efflux transmembrane transporter activity
GII77_RS02195	COG0745	RESPONSE REGULATOR receiver
GII77_RS02200	COG3850	Histidine kinase
GII77_RS02200	COG5002	protein histidine kinase activity
GII77_RS02205	COG0457	Tetratricopeptide repeat
GII77_RS02225	COG0527	aspartate kinase activity
GII77_RS02230	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII77_RS02235	COG4605	iron ion homeostasis
GII77_RS02240	COG4604	ABC transporter, ATP-binding protein
GII77_RS02245	COG4607	ABC-type enterochelin transport system periplasmic component
GII77_RS02250	COG2814	Major facilitator Superfamily
GII77_RS02255	COG1309	transcriptional regulator
GII77_RS02260	COG0778	Nitroreductase
GII77_RS02265	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GII77_RS02270	COG0640	Transcriptional regulator
GII77_RS02275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII77_RS02280	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GII77_RS02285	COG1012	belongs to the aldehyde dehydrogenase family
GII77_RS02290	COG4975	Glucose uptake
GII77_RS02295	COG1028	Short-chain dehydrogenase reductase Sdr
GII77_RS02300	COG4549	nuclear export factor GLE1
GII77_RS02305	COG2372	response to copper ion
GII77_RS02305	COG1276	copper resistance
GII77_RS02310	COG1349	DNA-binding transcription factor activity
GII77_RS02320	COG2213	PTS system mannitol-specific
GII77_RS02325	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII77_RS02330	COG0246	Mannitol dehydrogenase
GII77_RS02335	COG0473	3-isopropylmalate dehydrogenase activity
GII77_RS02340	COG0681	Belongs to the peptidase S26 family
GII77_RS02345	COG0412	Dienelactone hydrolase
GII77_RS02350	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GII77_RS02360	COG0561	phosphatase activity
GII77_RS02365	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GII77_RS02370	COG1914	H( )-stimulated, divalent metal cation uptake system
GII77_RS02375	COG4336	lyase activity
GII77_RS02380	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GII77_RS02385	COG1984	allophanate hydrolase subunit 2
GII77_RS02390	COG1414	Transcriptional regulator
GII77_RS02395	COG2755	lipolytic protein G-D-S-L family
GII77_RS02405	COG2329	Antibiotic biosynthesis monooxygenase
GII77_RS02410	COG0768	penicillin binding
GII77_RS02415	COG4989	oxidoreductase activity
GII77_RS02420	COG3711	transcriptional antiterminator
GII77_RS02425	COG0318	PFAM AMP-dependent synthetase and ligase
GII77_RS02430	COG2226	methyltransferase
GII77_RS02435	COG1028	Short-chain dehydrogenase reductase Sdr
GII77_RS02440	COG1917	Cupin 2, conserved barrel domain protein
GII77_RS02445	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII77_RS02450	COG3871	stress protein (general stress protein 26)
GII77_RS02460	COG2814	Major facilitator Superfamily
GII77_RS02465	COG1522	sequence-specific DNA binding
GII77_RS02470	COG0551	DNA topoisomerase type I activity
GII77_RS02470	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GII77_RS02475	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GII77_RS02480	COG3706	GGDEF domain
GII77_RS02485	COG5298	Protein conserved in bacteria
GII77_RS02490	COG1215	transferase activity, transferring glycosyl groups
GII77_RS02500	COG0531	amino acid
GII77_RS02510	COG0028	Belongs to the TPP enzyme family
GII77_RS02525	COG1914	H( )-stimulated, divalent metal cation uptake system
GII77_RS02530	COG2261	transglycosylase associated protein
GII77_RS02535	COG4876	unkown
GII77_RS02540	COG2217	Heavy metal translocating P-type atpase
GII77_RS02545	COG3729	General stress protein
GII77_RS02550	COG0662	Cupin 2, conserved barrel domain protein
GII77_RS02555	COG2329	Antibiotic biosynthesis monooxygenase
GII77_RS02560	COG3546	catalase activity
GII77_RS02565	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GII77_RS02570	COG3290	protein histidine kinase activity
GII77_RS02575	COG4565	transcriptional regulatory protein
GII77_RS02580	COG1301	dicarboxylic acid transport
GII77_RS02585	COG0628	permease
GII77_RS02590	COG1131	(ABC) transporter
GII77_RS02595	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GII77_RS02605	COG1960	acyl-CoA dehydrogenase activity
GII77_RS02620	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GII77_RS02625	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII77_RS02630	COG1181	Belongs to the D-alanine--D-alanine ligase family
GII77_RS02635	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GII77_RS02640	COG0513	Belongs to the DEAD box helicase family
GII77_RS02645	COG3402	PFAM membrane-flanked domain
GII77_RS02650	COG3428	Bacterial PH domain
GII77_RS02655	COG0705	Rhomboid family
GII77_RS02660	COG0736	holo-[acyl-carrier-protein] synthase activity
GII77_RS02665	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GII77_RS02670	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GII77_RS02675	COG0864	Transcriptional regulator
GII77_RS02680	COG2337	Toxic component of a toxin-antitoxin (TA) module
GII77_RS02685	COG1366	Belongs to the anti-sigma-factor antagonist family
GII77_RS02690	COG1366	Belongs to the anti-sigma-factor antagonist family
GII77_RS02695	COG2172	sigma factor antagonist activity
GII77_RS02700	COG2208	phosphoserine phosphatase activity
GII77_RS02705	COG1366	Belongs to the anti-sigma-factor antagonist family
GII77_RS02710	COG2172	sigma factor antagonist activity
GII77_RS02715	COG1191	sigma factor activity
GII77_RS02720	COG2208	phosphoserine phosphatase activity
GII77_RS02725	COG2183	response to ionizing radiation
GII77_RS02735	COG3091	SprT-like family
GII77_RS02775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII77_RS02815	COG1476	TRANSCRIPTIONal
GII77_RS02835	COG0693	protein deglycase activity
GII77_RS02840	COG1278	Cold shock
GII77_RS02845	COG1329	Transcriptional regulator
GII77_RS02850	COG0697	spore germination
GII77_RS02855	COG1917	Cupin 2, conserved barrel domain protein
GII77_RS02855	COG2207	Transcriptional regulator
GII77_RS02860	COG0697	spore germination
GII77_RS02865	COG3708	Transcriptional regulator
GII77_RS02865	COG2207	Transcriptional regulator
GII77_RS02870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII77_RS02875	COG0477	Major facilitator Superfamily
GII77_RS02885	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
GII77_RS02895	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII77_RS02900	COG1309	transcriptional regulator
GII77_RS02905	COG0697	spore germination
GII77_RS02910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII77_RS02915	COG2030	dehydratase
GII77_RS02920	COG3545	Serine hydrolase
GII77_RS02925	COG1733	regulation of RNA biosynthetic process
GII77_RS02930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII77_RS02935	COG1733	regulation of RNA biosynthetic process
GII77_RS02940	COG2249	NAD(P)H dehydrogenase (quinone) activity
GII77_RS02945	COG2814	Major facilitator Superfamily
GII77_RS02950	COG1309	transcriptional regulator
GII77_RS02955	COG0640	Transcriptional regulator
GII77_RS02960	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GII77_RS02970	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII77_RS02975	COG0697	spore germination
GII77_RS02980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII77_RS02985	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GII77_RS02990	COG0640	Transcriptional regulator
GII77_RS02995	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GII77_RS03010	COG4585	Histidine kinase
GII77_RS03015	COG2197	response regulator
GII77_RS03020	COG2409	Drug exporters of the RND superfamily
GII77_RS03025	COG0596	Alpha beta hydrolase
GII77_RS03030	COG1811	Na channel or pump
GII77_RS03035	COG0789	Transcriptional regulator
GII77_RS03035	COG4978	Transcriptional regulator
GII77_RS03040	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GII77_RS03045	COG0778	Nitroreductase
GII77_RS03050	COG0346	lactoylglutathione lyase activity
GII77_RS03055	COG2259	Doxx family
GII77_RS03060	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII77_RS03075	COG2323	membrane
GII77_RS03080	COG2323	membrane
GII77_RS03085	COG0071	Belongs to the small heat shock protein (HSP20) family
GII77_RS03100	COG1309	transcriptional regulator
GII77_RS03110	COG0456	acetyltransferase
GII77_RS03115	COG0488	(ABC) transporter
GII77_RS03120	COG1113	amino acid transport
GII77_RS03125	COG2318	DinB family
GII77_RS03130	COG1846	Transcriptional regulator
GII77_RS03135	COG2409	Drug exporters of the RND superfamily
GII77_RS03135	COG1033	growth of symbiont in host cell
GII77_RS03140	COG0778	Nitroreductase
GII77_RS03145	COG1846	Transcriptional regulator
GII77_RS03150	COG2814	Major facilitator Superfamily
GII77_RS03155	COG0730	response to heat
GII77_RS03160	COG1802	Transcriptional regulator
GII77_RS03165	COG1388	LysM domain
GII77_RS03165	COG3858	chitin binding
GII77_RS03170	COG1819	glycosyl
GII77_RS03180	COG1785	Belongs to the alkaline phosphatase family
GII77_RS03185	COG5646	InterPro IPR014922
GII77_RS03195	COG0454	-acetyltransferase
GII77_RS03200	COG1078	dGTPase activity
GII77_RS03205	COG1388	LysM domain
GII77_RS03210	COG2814	Major facilitator Superfamily
GII77_RS03215	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII77_RS03220	COG1447	Phosphotransferase system cellobiose-specific component IIA
GII77_RS03225	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII77_RS03230	COG2723	6-phospho-beta-galactosidase activity
GII77_RS03235	COG2188	Transcriptional regulator
GII77_RS03240	COG1940	carbohydrate kinase activity
GII77_RS03245	COG1482	cell wall glycoprotein biosynthetic process
GII77_RS03250	COG4124	Belongs to the glycosyl hydrolase 26 family
GII77_RS03295	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GII77_RS03300	COG0802	atpase or kinase
GII77_RS03305	COG1214	PFAM Peptidase M22, glycoprotease
GII77_RS03310	COG0456	acetyltransferase
GII77_RS03315	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GII77_RS03320	COG0488	(ABC) transporter
GII77_RS03325	COG0315	cyclic pyranopterin monophosphate synthase activity
GII77_RS03330	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GII77_RS03335	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GII77_RS03340	COG0805	protein transport
GII77_RS03350	COG1266	CAAX protease self-immunity
GII77_RS03360	COG0459	protein refolding
GII77_RS03365	COG4974	Belongs to the 'phage' integrase family
GII77_RS03370	COG2856	Zn peptidase
GII77_RS03380	COG1396	sequence-specific DNA binding
GII77_RS03395	COG3646	Phage regulatory protein
GII77_RS03395	COG3645	SOS response
GII77_RS03430	COG3935	DnaD domain protein
GII77_RS03435	COG1484	DNA-dependent DNA replication
GII77_RS03485	COG3677	Transposase
GII77_RS03500	COG5484	DNA packaging
GII77_RS03505	COG1783	phage Terminase large subunit
GII77_RS03635	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII77_RS03635	COG3409	Peptidoglycan-binding domain 1 protein
GII77_RS03635	COG1388	LysM domain
GII77_RS03680	COG1073	alpha beta
GII77_RS03685	COG0457	Tetratricopeptide repeat
GII77_RS03690	COG1063	alcohol dehydrogenase
GII77_RS03695	COG2211	Major facilitator Superfamily
GII77_RS03700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII77_RS03705	COG1842	Phage shock protein A
GII77_RS03710	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GII77_RS03715	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GII77_RS03720	COG4260	virion core protein, lumpy skin disease virus
GII77_RS03730	COG2814	Major facilitator Superfamily
GII77_RS03735	COG1063	alcohol dehydrogenase
GII77_RS03740	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GII77_RS03745	COG0823	Involved in the tonB-independent uptake of proteins
GII77_RS03760	COG2267	carboxylic ester hydrolase activity
GII77_RS03770	COG2132	Multicopper oxidase
GII77_RS03775	COG1113	amino acid transport
GII77_RS03785	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GII77_RS03790	COG0714	Associated with various cellular activities
GII77_RS03795	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
GII77_RS03800	COG1305	Transglutaminase-like
GII77_RS03805	COG0519	Catalyzes the synthesis of GMP from XMP
GII77_RS03805	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GII77_RS03820	COG2252	PERMEase
GII77_RS03825	COG3064	Membrane
GII77_RS03835	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
GII77_RS03845	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GII77_RS03850	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GII77_RS03855	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GII77_RS03860	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GII77_RS03865	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GII77_RS03870	COG0047	phosphoribosylformylglycinamidine synthase activity
GII77_RS03875	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GII77_RS03880	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GII77_RS03885	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GII77_RS03890	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GII77_RS03895	COG0138	bifunctional purine biosynthesis protein purh
GII77_RS03900	COG0151	Belongs to the GarS family
GII77_RS03905	COG1522	sequence-specific DNA binding
GII77_RS03910	COG0531	amino acid
GII77_RS03920	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GII77_RS03925	COG1470	cell adhesion involved in biofilm formation
GII77_RS03930	COG4496	protein, YerC YecD
GII77_RS03935	COG0069	glutamate synthase activity
GII77_RS03940	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
GII77_RS03945	COG0210	DNA helicase
GII77_RS03950	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GII77_RS03955	COG4851	CamS sex pheromone cAM373 precursor
GII77_RS03960	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII77_RS03965	COG1285	pathogenesis
GII77_RS03970	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII77_RS03975	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GII77_RS03980	COG0154	amidase activity
GII77_RS03985	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GII77_RS03990	COG1309	transcriptional regulator
GII77_RS03995	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GII77_RS04000	COG1597	lipid kinase activity
GII77_RS04005	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GII77_RS04010	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GII77_RS04020	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GII77_RS04045	COG3391	amine dehydrogenase activity
GII77_RS04060	COG0457	Tetratricopeptide repeat
GII77_RS04070	COG0217	transcriptional regulatory protein
GII77_RS04080	COG1309	transcriptional regulator
GII77_RS04085	COG3631	Ketosteroid isomerase-related protein
GII77_RS04090	COG0702	epimerase
GII77_RS04105	COG3546	catalase activity
GII77_RS04110	COG0454	-acetyltransferase
GII77_RS04120	COG5578	integral membrane protein
GII77_RS04125	COG2972	Histidine kinase
GII77_RS04130	COG2207	Transcriptional regulator
GII77_RS04130	COG4753	response regulator
GII77_RS04135	COG1653	transport
GII77_RS04140	COG1175	transmembrane transport
GII77_RS04145	COG0395	ABC-type sugar transport system, permease component
GII77_RS04150	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GII77_RS04155	COG2207	Transcriptional regulator
GII77_RS04160	COG2755	lipolytic protein G-D-S-L family
GII77_RS04170	COG5578	integral membrane protein
GII77_RS04175	COG3401	FG-GAP repeat protein
GII77_RS04180	COG3401	FG-GAP repeat protein
GII77_RS04185	COG2755	lipolytic protein G-D-S-L family
GII77_RS04190	COG1874	Beta-galactosidase
GII77_RS04200	COG1653	transport
GII77_RS04205	COG4209	transmembrane transport
GII77_RS04210	COG0395	ABC-type sugar transport system, permease component
GII77_RS04215	COG1486	melibiose metabolic process
GII77_RS04220	COG2323	membrane
GII77_RS04225	COG2329	Antibiotic biosynthesis monooxygenase
GII77_RS04230	COG0346	lactoylglutathione lyase activity
GII77_RS04245	COG5583	Uncharacterized small protein (DUF2292)
GII77_RS04250	COG0670	Belongs to the BI1 family
GII77_RS04260	COG1846	Transcriptional regulator
GII77_RS04265	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GII77_RS04275	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GII77_RS04275	COG2124	cytochrome p450
GII77_RS04280	COG1368	sulfuric ester hydrolase activity
GII77_RS04285	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GII77_RS04290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII77_RS04295	COG1442	glycosyl transferase family 8
GII77_RS04300	COG1216	Glycosyl transferase, family 2
GII77_RS04305	COG1442	glycosyl transferase family 8
GII77_RS04310	COG2223	nitrite transmembrane transporter activity
GII77_RS04315	COG1011	Hydrolase
GII77_RS04320	COG0531	amino acid
GII77_RS04325	COG1012	belongs to the aldehyde dehydrogenase family
GII77_RS04330	COG0840	transmembrane signaling receptor activity
GII77_RS04335	COG0488	(ABC) transporter
GII77_RS04345	COG0789	Transcriptional regulator
GII77_RS04350	COG2814	Major facilitator Superfamily
GII77_RS04365	COG0488	(ABC) transporter
GII77_RS04370	COG0513	Belongs to the DEAD box helicase family
GII77_RS04375	COG0456	acetyltransferase
GII77_RS04380	COG2130	NADP-dependent
GII77_RS04385	COG2211	Major facilitator Superfamily
GII77_RS04390	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GII77_RS04395	COG1120	ATPase activity
GII77_RS04400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII77_RS04405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII77_RS04410	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GII77_RS04425	COG3866	Pectate lyase
GII77_RS04430	COG0471	metal ion transport
GII77_RS04435	COG3290	protein histidine kinase activity
GII77_RS04440	COG4565	transcriptional regulatory protein
GII77_RS04445	COG3181	Tripartite tricarboxylate transporter family receptor
GII77_RS04450	COG2851	Citrate transporter
GII77_RS04455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII77_RS04460	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
GII77_RS04465	COG1254	Belongs to the acylphosphatase family
GII77_RS04470	COG2258	MOSC domain
GII77_RS04490	COG0024	Methionine aminopeptidase
GII77_RS04495	COG1263	PTS System
GII77_RS04495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII77_RS04500	COG1368	sulfuric ester hydrolase activity
GII77_RS04515	COG1115	amino acid carrier protein
GII77_RS04530	COG0697	spore germination
GII77_RS04535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII77_RS04535	COG1263	PTS System
GII77_RS04540	COG0366	Alpha amylase catalytic
GII77_RS04545	COG2188	Transcriptional regulator
GII77_RS04550	COG0778	Nitroreductase
GII77_RS04555	COG0737	Belongs to the 5'-nucleotidase family
GII77_RS04560	COG0693	protein deglycase activity
GII77_RS04565	COG2814	Major facilitator Superfamily
GII77_RS04570	COG4840	Belongs to the UPF0435 family
GII77_RS04575	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GII77_RS04580	COG4980	gas vesicle protein
GII77_RS04585	COG1295	ribonuclease BN
GII77_RS04590	COG0477	Major facilitator Superfamily
GII77_RS04595	COG0387	Pfam Sodium calcium exchanger
GII77_RS04605	COG0668	transmembrane transport
GII77_RS04610	COG0535	radical SAM domain protein
GII77_RS04620	COG0726	polysaccharide deacetylase
GII77_RS04625	COG2084	Dehydrogenase
GII77_RS04630	COG0598	Magnesium transport protein CorA
GII77_RS04635	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GII77_RS04640	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GII77_RS04650	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GII77_RS04655	COG4637	Psort location Cytoplasmic, score
GII77_RS04665	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GII77_RS04670	COG0022	dehydrogenase e1 component
GII77_RS04675	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII77_RS04680	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GII77_RS04685	COG3284	Transcriptional regulator
GII77_RS04695	COG1742	UPF0060 membrane protein
GII77_RS04715	COG4842	Belongs to the WXG100 family
GII77_RS04720	COG1486	melibiose metabolic process
GII77_RS04725	COG1737	Transcriptional regulator
GII77_RS04730	COG1263	PTS System
GII77_RS04730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII77_RS04735	COG1132	(ABC) transporter
GII77_RS04740	COG1132	(ABC) transporter
GII77_RS04745	COG2259	Doxx family
GII77_RS04750	COG2514	catechol 2,3-dioxygenase activity
GII77_RS04755	COG4585	Histidine kinase
GII77_RS04760	COG2197	response regulator
GII77_RS04765	COG1131	(ABC) transporter
GII77_RS04770	COG0842	Transport permease protein
GII77_RS04770	COG1511	domain protein
GII77_RS04775	COG0842	Transport permease protein
GII77_RS04780	COG1695	Transcriptional regulator
GII77_RS04785	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GII77_RS04790	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
GII77_RS04795	COG2318	DinB family
GII77_RS04800	COG2814	Major facilitator Superfamily
GII77_RS04805	COG1846	Transcriptional regulator
GII77_RS04810	COG0392	lysyltransferase activity
GII77_RS04810	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GII77_RS04815	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII77_RS04820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII77_RS04825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII77_RS04830	COG0384	phenazine biosynthesis protein PhzF
GII77_RS04835	COG0778	Nitroreductase
GII77_RS04850	COG1090	epimerase
GII77_RS04855	COG2137	regulation of response to DNA damage stimulus
GII77_RS04865	COG2814	Major facilitator Superfamily
GII77_RS04880	COG3103	Sh3 type 3 domain protein
GII77_RS04885	COG5658	integral membrane protein
GII77_RS04890	COG0596	Alpha beta hydrolase
GII77_RS04895	COG0463	Glycosyl transferase, family 2
GII77_RS04900	COG4485	Bacterial membrane protein, YfhO
GII77_RS04905	COG1988	membrane-bound metal-dependent
GII77_RS04910	COG1194	a g-specific adenine glycosylase
GII77_RS04920	COG1028	Short-chain dehydrogenase reductase Sdr
GII77_RS04935	COG3557	Belongs to the UPF0374 family
GII77_RS04940	COG1132	(ABC) transporter
GII77_RS04945	COG4129	membrane
GII77_RS04950	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GII77_RS04955	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GII77_RS04960	COG0735	belongs to the Fur family
GII77_RS05070	COG4326	sporulation control protein
GII77_RS05080	COG5577	PFAM Coat F domain
GII77_RS05085	COG3340	Belongs to the peptidase S51 family
GII77_RS05090	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GII77_RS05095	COG0277	FAD linked oxidase domain protein
GII77_RS05105	COG0753	catalase activity
GII77_RS05110	COG1116	anion transmembrane transporter activity
GII77_RS05115	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GII77_RS05120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GII77_RS05125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII77_RS05135	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GII77_RS05145	COG1476	TRANSCRIPTIONal
GII77_RS05155	COG3382	B3 4 domain protein
GII77_RS05160	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GII77_RS05170	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GII77_RS05175	COG0789	Transcriptional regulator
GII77_RS05180	COG1664	Polymer-forming cytoskeletal
GII77_RS05185	COG1664	Polymer-forming cytoskeletal
GII77_RS05190	COG2766	serine protein kinase
GII77_RS05195	COG2718	Belongs to the UPF0229 family
GII77_RS05200	COG1846	Transcriptional regulator
GII77_RS05205	COG1566	PFAM secretion protein HlyD family protein
GII77_RS05210	COG2814	Major facilitator Superfamily
GII77_RS05215	COG0655	NAD(P)H dehydrogenase (quinone) activity
GII77_RS05235	COG1725	Transcriptional regulator
GII77_RS05240	COG1131	(ABC) transporter
GII77_RS05245	COG1131	(ABC) transporter
GII77_RS05250	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GII77_RS05255	COG1278	Cold shock
GII77_RS05260	COG1464	Belongs to the NlpA lipoprotein family
GII77_RS05265	COG3706	GGDEF domain
GII77_RS05270	COG1823	symporter activity
GII77_RS05290	COG5577	PFAM Coat F domain
GII77_RS05295	COG1525	nuclease
GII77_RS05295	COG4085	toxin activity
GII77_RS05295	COG0737	Belongs to the 5'-nucleotidase family
GII77_RS05300	COG3764	Sortase (surface protein transpeptidase)
GII77_RS05305	COG0564	pseudouridine synthase activity
GII77_RS05315	COG0517	IMP dehydrogenase activity
GII77_RS05320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GII77_RS05325	COG3153	acetyltransferase
GII77_RS05325	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GII77_RS05330	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GII77_RS05335	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GII77_RS05340	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GII77_RS05345	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GII77_RS05350	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GII77_RS05355	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GII77_RS05360	COG4585	Histidine kinase
GII77_RS05360	COG2203	Gaf domain
GII77_RS05365	COG2197	response regulator
GII77_RS05370	COG0431	NADPH-dependent FMN reductase
GII77_RS05385	COG1388	LysM domain
GII77_RS05385	COG0791	NLP P60 protein
GII77_RS05390	COG1959	2 iron, 2 sulfur cluster binding
GII77_RS05395	COG0668	transmembrane transport
GII77_RS05400	COG2719	SpoVR family
GII77_RS05405	COG1785	Belongs to the alkaline phosphatase family
GII77_RS05410	COG1388	LysM domain
GII77_RS05410	COG0791	NLP P60 protein
GII77_RS05415	COG0583	DNA-binding transcription factor activity
GII77_RS05420	COG0372	Belongs to the citrate synthase family
GII77_RS05425	COG1028	Short-chain dehydrogenase reductase Sdr
GII77_RS05430	COG0531	amino acid
GII77_RS05435	COG0733	neurotransmitter:sodium symporter activity
GII77_RS05440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII77_RS05445	COG0456	acetyltransferase
GII77_RS05460	COG1595	DNA-templated transcription, initiation
GII77_RS05465	COG0667	Aldo Keto reductase
GII77_RS05470	COG0204	Acyl-transferase
GII77_RS05475	COG1253	flavin adenine dinucleotide binding
GII77_RS05480	COG0789	Transcriptional regulator
GII77_RS05485	COG0436	Aminotransferase
GII77_RS05490	COG1253	flavin adenine dinucleotide binding
GII77_RS05495	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GII77_RS05500	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GII77_RS05505	COG0584	glycerophosphoryl diester phosphodiesterase
GII77_RS05515	COG0668	transmembrane transport
GII77_RS05520	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GII77_RS05525	COG0726	polysaccharide deacetylase
GII77_RS05530	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII77_RS05535	COG1757	Na H antiporter
GII77_RS05540	COG0589	response to stress
GII77_RS05550	COG1132	(ABC) transporter
GII77_RS05555	COG1132	(ABC) transporter
GII77_RS05560	COG0702	epimerase
GII77_RS05580	COG0189	ligase activity
GII77_RS05585	COG0189	ligase activity
GII77_RS05590	COG4399	Belongs to the UPF0754 family
GII77_RS05595	COG3679	Belongs to the UPF0342 family
GII77_RS05600	COG4335	DNA alkylation repair
GII77_RS05605	COG0561	phosphatase activity
GII77_RS05610	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GII77_RS05615	COG0475	glutathione-regulated potassium exporter activity
GII77_RS05620	COG0490	domain, Protein
GII77_RS05630	COG1024	Enoyl-CoA hydratase
GII77_RS05640	COG4152	abc transporter atp-binding protein
GII77_RS05645	COG1668	transmembrane transport
GII77_RS05650	COG0420	3'-5' exonuclease activity
GII77_RS05655	COG4717	serine-type aminopeptidase activity
GII77_RS05660	COG3481	metal-dependent phosphohydrolase, HD sub domain
GII77_RS05670	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GII77_RS05700	COG1846	Transcriptional regulator
GII77_RS05705	COG4980	gas vesicle protein
GII77_RS05720	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GII77_RS05725	COG0537	adenosine 5'-monophosphoramidase activity
GII77_RS05730	COG1131	(ABC) transporter
GII77_RS05735	COG4473	ABC transporter
GII77_RS05745	COG1473	amidohydrolase
GII77_RS05750	COG3069	C4-dicarboxylate transmembrane transporter activity
GII77_RS05760	COG2329	Antibiotic biosynthesis monooxygenase
GII77_RS05765	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII77_RS05770	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GII77_RS05775	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GII77_RS05780	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GII77_RS05785	COG1309	transcriptional regulator
GII77_RS05790	COG1511	domain protein
GII77_RS05795	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GII77_RS05800	COG4377	Putative membrane peptidase family (DUF2324)
GII77_RS05810	COG1363	Peptidase, m42
GII77_RS05815	COG4405	Protein conserved in bacteria
GII77_RS05820	COG1301	dicarboxylic acid transport
GII77_RS05830	COG1234	tRNA 3'-trailer cleavage
GII77_RS05835	COG0095	Lipoate-protein ligase
GII77_RS05840	COG0702	epimerase
GII77_RS05845	COG0318	PFAM AMP-dependent synthetase and ligase
GII77_RS05855	COG0501	Belongs to the peptidase M48B family
GII77_RS05865	COG0456	acetyltransferase
GII77_RS05870	COG0604	alcohol dehydrogenase
GII77_RS05875	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GII77_RS05880	COG0406	alpha-ribazole phosphatase activity
GII77_RS05885	COG0183	Belongs to the thiolase family
GII77_RS05890	COG0318	PFAM AMP-dependent synthetase and ligase
GII77_RS05895	COG1268	BioY protein
GII77_RS05900	COG0840	transmembrane signaling receptor activity
GII77_RS05905	COG0723	plastoquinol--plastocyanin reductase activity
GII77_RS05905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GII77_RS05910	COG1028	Short-chain dehydrogenase reductase Sdr
GII77_RS05920	COG4903	ComK protein
GII77_RS05925	COG1028	Short-chain dehydrogenase reductase Sdr
GII77_RS05935	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII77_RS05950	COG0398	Pfam SNARE associated Golgi protein
GII77_RS05955	COG0681	Belongs to the peptidase S26 family
GII77_RS05960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GII77_RS05965	COG1846	Transcriptional regulator
GII77_RS05970	COG0738	Major facilitator superfamily
GII77_RS05975	COG0673	inositol 2-dehydrogenase activity
GII77_RS05980	COG0561	phosphatase activity
GII77_RS05985	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GII77_RS05990	COG1609	Transcriptional regulator
GII77_RS05995	COG3180	Ammonia monooxygenase
GII77_RS06000	COG0477	Major facilitator Superfamily
GII77_RS06000	COG2814	Major facilitator Superfamily
GII77_RS06005	COG4533	DNA binding
GII77_RS06015	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
GII77_RS06020	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GII77_RS06025	COG1074	ATP-dependent DNA helicase activity
GII77_RS06030	COG0420	3'-5' exonuclease activity
GII77_RS06035	COG0419	ATPase involved in DNA repair
GII77_RS06040	COG1403	HNH endonuclease
GII77_RS06080	COG5337	Spore coat protein CotH
GII77_RS06085	COG0179	Fumarylacetoacetate (FAA) hydrolase
GII77_RS06095	COG1404	Belongs to the peptidase S8 family
GII77_RS06105	COG0367	asparagine synthase
GII77_RS06110	COG2318	DinB family
GII77_RS06115	COG1562	ergosterol biosynthetic process
GII77_RS06120	COG0534	Mate efflux family protein
GII77_RS06125	COG2207	Transcriptional regulator
GII77_RS06125	COG1917	Cupin 2, conserved barrel domain protein
GII77_RS06130	COG1609	Transcriptional regulator
GII77_RS06135	COG0673	inositol 2-dehydrogenase activity
GII77_RS06140	COG2318	DinB family
GII77_RS06145	COG1279	arginine transmembrane transporter activity
GII77_RS06150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII77_RS06155	COG1357	PFAM Pentapeptide repeats (8 copies)
GII77_RS06160	COG2267	carboxylic ester hydrolase activity
GII77_RS06165	COG0529	Catalyzes the synthesis of activated sulfate
GII77_RS06170	COG2046	Belongs to the sulfate adenylyltransferase family
GII77_RS06175	COG0175	sulfate reduction
GII77_RS06180	COG2045	Belongs to the ComB family
GII77_RS06185	COG1809	phosphosulfolactate synthase activity
GII77_RS06190	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII77_RS06195	COG4948	Mandelate Racemase Muconate Lactonizing
GII77_RS06200	COG2814	Major facilitator Superfamily
GII77_RS06205	COG0454	-acetyltransferase
GII77_RS06210	COG2153	protein acetylation
GII77_RS06215	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GII77_RS06215	COG0646	methionine synthase
GII77_RS06220	COG1666	GTP binding
GII77_RS06225	COG2996	Protein conserved in bacteria
GII77_RS06245	COG1695	Transcriptional regulator
GII77_RS06260	COG3227	Zinc metalloprotease (Elastase)
GII77_RS06265	COG1307	EDD domain protein, DegV family
GII77_RS06270	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII77_RS06285	COG0561	phosphatase activity
GII77_RS06290	COG1073	alpha beta
GII77_RS06295	COG2151	metal-sulfur cluster biosynthetic enzyme
GII77_RS06310	COG2271	Major facilitator Superfamily
GII77_RS06315	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GII77_RS06320	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GII77_RS06330	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GII77_RS06335	COG0505	Belongs to the CarA family
GII77_RS06340	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GII77_RS06345	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GII77_RS06360	COG2267	carboxylic ester hydrolase activity
GII77_RS06370	COG1744	ABC transporter substrate-binding protein PnrA-like
GII77_RS06385	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GII77_RS06390	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GII77_RS06395	COG5504	Zn-dependent protease
GII77_RS06400	COG0444	Belongs to the ABC transporter superfamily
GII77_RS06405	COG4608	Belongs to the ABC transporter superfamily
GII77_RS06415	COG0601	transmembrane transport
GII77_RS06420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GII77_RS06430	COG0180	Tryptophanyl-tRNA synthetase
GII77_RS06435	COG4166	transmembrane transport
GII77_RS06440	COG0601	transmembrane transport
GII77_RS06445	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GII77_RS06450	COG0444	Belongs to the ABC transporter superfamily
GII77_RS06455	COG4608	Belongs to the ABC transporter superfamily
GII77_RS06460	COG2814	Major facilitator Superfamily
GII77_RS06465	COG0456	acetyltransferase
GII77_RS06470	COG1393	Belongs to the ArsC family
GII77_RS06475	COG0861	Integral membrane protein TerC family
GII77_RS06485	COG4862	establishment of competence for transformation
GII77_RS06495	COG4469	Competence protein
GII77_RS06500	COG1164	Oligoendopeptidase f
GII77_RS06510	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GII77_RS06515	COG2346	COG2346, Truncated hemoglobins
GII77_RS06520	COG0741	lytic transglycosylase activity
GII77_RS06525	COG4116	CYTH
GII77_RS06535	COG2357	RelA SpoT domain protein
GII77_RS06540	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GII77_RS06545	COG0564	pseudouridine synthase activity
GII77_RS06550	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GII77_RS06555	COG0569	domain protein
GII77_RS06555	COG0475	glutathione-regulated potassium exporter activity
GII77_RS06560	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GII77_RS06565	COG0352	thiamine-phosphate diphosphorylase activity
GII77_RS06570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GII77_RS06575	COG2104	thiamine diphosphate biosynthetic process
GII77_RS06580	COG2022	thiamine diphosphate biosynthetic process
GII77_RS06585	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GII77_RS06590	COG0351	phosphomethylpyrimidine kinase
GII77_RS06595	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GII77_RS06650	COG0210	DNA helicase
GII77_RS06660	COG2153	protein acetylation
GII77_RS06665	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GII77_RS06670	COG2382	esterase
GII77_RS06690	COG0626	cystathionine gamma-synthase activity
GII77_RS06695	COG0626	cystathionine gamma-synthase activity
GII77_RS06700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII77_RS06705	COG5505	Protein of unknown function (DUF819)
GII77_RS06715	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GII77_RS06830	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GII77_RS06830	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GII77_RS06855	COG1780	Probably involved in ribonucleotide reductase function
GII77_RS06860	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GII77_RS06875	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GII77_RS06885	COG0756	dUTP diphosphatase activity
GII77_RS06890	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
GII77_RS06895	COG3584	3D domain protein
GII77_RS06935	COG1793	dna ligase
GII77_RS06960	COG5434	Belongs to the glycosyl hydrolase 28 family
GII77_RS06960	COG3420	alginic acid biosynthetic process
GII77_RS06965	COG4195	phage-related replication protein
GII77_RS06975	COG1216	Glycosyl transferase, family 2
GII77_RS07030	COG0740	serine-type endopeptidase activity
GII77_RS07080	COG3953	SLT domain
GII77_RS07080	COG5280	Phage tail tape measure protein TP901
GII77_RS07115	COG1388	LysM domain
GII77_RS07115	COG3409	Peptidoglycan-binding domain 1 protein
GII77_RS07115	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII77_RS07190	COG3677	Transposase
GII77_RS07205	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GII77_RS07210	COG1028	Short-chain dehydrogenase reductase Sdr
GII77_RS07220	COG3711	transcriptional antiterminator
GII77_RS07220	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII77_RS07225	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII77_RS07225	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII77_RS07225	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII77_RS07230	COG1482	cell wall glycoprotein biosynthetic process
GII77_RS07240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII77_RS07250	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GII77_RS07265	COG0109	protoheme IX farnesyltransferase activity
GII77_RS07275	COG0726	polysaccharide deacetylase
GII77_RS07290	COG5504	Zn-dependent protease
GII77_RS07295	COG2205	protein histidine kinase activity
GII77_RS07305	COG3383	formate dehydrogenase (NAD+) activity
GII77_RS07310	COG2427	Protein of unknown function (DUF1641)
GII77_RS07320	COG1051	belongs to the nudix hydrolase family
GII77_RS07330	COG2124	cytochrome p450
GII77_RS07335	COG1819	glycosyl
GII77_RS07345	COG1587	Uroporphyrinogen-III synthase
GII77_RS07350	COG0390	transport system, permease component
GII77_RS07355	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GII77_RS07360	COG0697	spore germination
GII77_RS07365	COG4297	protein containing double-stranded beta helix domain
GII77_RS07375	COG1252	NADH dehydrogenase
GII77_RS07380	COG1904	glucuronate isomerase
GII77_RS07385	COG2211	Major facilitator Superfamily
GII77_RS07390	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GII77_RS07395	COG1063	alcohol dehydrogenase
GII77_RS07400	COG1312	Catalyzes the dehydration of D-mannonate
GII77_RS07405	COG1028	Short-chain dehydrogenase reductase Sdr
GII77_RS07410	COG2271	Major facilitator Superfamily
GII77_RS07415	COG1609	Transcriptional regulator
GII77_RS07420	COG0246	Mannitol dehydrogenase
GII77_RS07425	COG2721	sulfolactate sulfo-lyase activity
GII77_RS07430	COG0730	response to heat
GII77_RS07435	COG2318	DinB family
GII77_RS07440	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GII77_RS07445	COG0457	Tetratricopeptide repeat
GII77_RS07455	COG2350	Protein conserved in bacteria
GII77_RS07460	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII77_RS07460	COG1388	LysM domain
GII77_RS07460	COG3409	Peptidoglycan-binding domain 1 protein
GII77_RS07470	COG4195	phage-related replication protein
GII77_RS07475	COG3546	catalase activity
GII77_RS07480	COG2856	Zn peptidase
GII77_RS07485	COG1396	sequence-specific DNA binding
GII77_RS07495	COG1522	sequence-specific DNA binding
GII77_RS07500	COG1484	DNA-dependent DNA replication
GII77_RS07520	COG1595	DNA-templated transcription, initiation
GII77_RS07525	COG3728	DNA packaging
GII77_RS07525	COG5484	DNA packaging
GII77_RS07530	COG1783	phage Terminase large subunit
GII77_RS07535	COG5518	Phage portal protein
GII77_RS07540	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GII77_RS07545	COG4653	Phage capsid family
GII77_RS07595	COG3953	SLT domain
GII77_RS07595	COG5412	phage tail tape measure protein
GII77_RS07595	COG5412	phage tail tape measure protein
GII77_RS07595	COG3953	SLT domain
GII77_RS07600	COG1652	LysM domain
GII77_RS07605	COG4193	domain, Protein
GII77_RS07615	COG3628	GPW Gp25 family protein
GII77_RS07620	COG3299	homolog of phage Mu protein gp47
GII77_RS07625	COG3778	Protein conserved in bacteria
GII77_RS07665	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII77_RS07665	COG3409	Peptidoglycan-binding domain 1 protein
GII77_RS07685	COG0306	phosphate transporter
GII77_RS07690	COG1392	Phosphate transport regulator
GII77_RS07695	COG0531	amino acid
GII77_RS07700	COG0346	lactoylglutathione lyase activity
GII77_RS07705	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GII77_RS07710	COG0463	Glycosyl transferase, family 2
GII77_RS07715	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII77_RS07720	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII77_RS07725	COG2362	D-Aminopeptidase
GII77_RS07730	COG0601	transmembrane transport
GII77_RS07735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GII77_RS07740	COG0444	Belongs to the ABC transporter superfamily
GII77_RS07745	COG4166	transmembrane transport
GII77_RS07750	COG1619	proteins homologs of microcin C7 resistance protein MccF
GII77_RS07755	COG4948	Mandelate Racemase Muconate Lactonizing
GII77_RS07760	COG0791	NLP P60 protein
GII77_RS07765	COG4608	Belongs to the ABC transporter superfamily
GII77_RS07770	COG2706	6-phosphogluconolactonase activity
GII77_RS07775	COG1834	amidinotransferase
GII77_RS07780	COG1607	acyl-coa hydrolase
GII77_RS07785	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GII77_RS07785	COG1017	nitric oxide dioxygenase activity
GII77_RS07795	COG2323	membrane
GII77_RS07800	COG2318	DinB family
GII77_RS07805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII77_RS07810	COG2076	Multidrug Resistance protein
GII77_RS07815	COG2076	Multidrug Resistance protein
GII77_RS07820	COG0788	formyltetrahydrofolate deformylase activity
GII77_RS07825	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GII77_RS07830	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GII77_RS07835	COG1764	response to oxidative stress
GII77_RS07840	COG1846	Transcriptional regulator
GII77_RS07845	COG1764	response to oxidative stress
GII77_RS07855	COG0590	tRNA wobble adenosine to inosine editing
GII77_RS07860	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GII77_RS07865	COG1404	Belongs to the peptidase S8 family
GII77_RS07870	COG1366	Belongs to the anti-sigma-factor antagonist family
GII77_RS07875	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GII77_RS07880	COG1122	ATPase activity
GII77_RS07885	COG4721	ABC-type cobalt transport system, permease component
GII77_RS07895	COG0745	RESPONSE REGULATOR receiver
GII77_RS07900	COG3850	Histidine kinase
GII77_RS07900	COG5002	protein histidine kinase activity
GII77_RS07905	COG3212	peptidase
GII77_RS07910	COG3212	peptidase
GII77_RS07920	COG2239	Acts as a magnesium transporter
GII77_RS07925	COG0789	Transcriptional regulator
GII77_RS07940	COG1846	Transcriptional regulator
GII77_RS07945	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GII77_RS07950	COG0726	polysaccharide deacetylase
GII77_RS07955	COG1408	metallophosphoesterase
GII77_RS07965	COG0463	Glycosyl transferase, family 2
GII77_RS07970	COG1793	dna ligase
GII77_RS07970	COG3285	dna ligase
GII77_RS07975	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GII77_RS07980	COG5001	Diguanylate cyclase
GII77_RS07980	COG3300	MHYT domain
GII77_RS07985	COG0586	Pfam SNARE associated Golgi protein
GII77_RS07990	COG0861	Integral membrane protein TerC family
GII77_RS07995	COG1191	sigma factor activity
GII77_RS08015	COG0501	Belongs to the peptidase M48B family
GII77_RS08020	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GII77_RS08035	COG3594	Acyltransferase
GII77_RS08040	COG5002	protein histidine kinase activity
GII77_RS08045	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GII77_RS08055	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GII77_RS08060	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
GII77_RS08065	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GII77_RS08070	COG0436	Aminotransferase
GII77_RS08075	COG1850	ribulose-bisphosphate carboxylase activity
GII77_RS08080	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
GII77_RS08085	COG0235	Class ii aldolase
GII77_RS08090	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
GII77_RS08095	COG3339	Conserved Protein
GII77_RS08110	COG3852	Histidine kinase
GII77_RS08115	COG1846	Transcriptional regulator
GII77_RS08120	COG1360	Flagellar Motor Protein
GII77_RS08125	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GII77_RS08130	COG0542	response to heat
GII77_RS08135	COG3949	Membrane
GII77_RS08140	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GII77_RS08145	COG0720	synthase
GII77_RS08150	COG0602	queuosine metabolic process
GII77_RS08155	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GII77_RS08160	COG1733	regulation of RNA biosynthetic process
GII77_RS08165	COG1028	Short-chain dehydrogenase reductase Sdr
GII77_RS08170	COG4641	Protein conserved in bacteria
GII77_RS08170	COG1388	LysM domain
GII77_RS08175	COG1388	LysM domain
GII77_RS08180	COG3858	chitin binding
GII77_RS08190	COG4873	Protein conserved in bacteria
GII77_RS08200	COG3773	Cell wall hydrolase
GII77_RS08205	COG2244	polysaccharide biosynthetic process
GII77_RS08210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII77_RS08215	COG2217	Heavy metal translocating P-type atpase
GII77_RS08225	COG0006	proline dipeptidase activity
GII77_RS08230	COG1609	Transcriptional regulator
GII77_RS08235	COG3711	transcriptional antiterminator
GII77_RS08240	COG2190	(PTS) system
GII77_RS08240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII77_RS08240	COG1263	PTS System
GII77_RS08245	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII77_RS08250	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GII77_RS08260	COG1533	DNA photolyase activity
GII77_RS08265	COG0456	acetyltransferase
GII77_RS08270	COG0840	transmembrane signaling receptor activity
GII77_RS08275	COG2084	Dehydrogenase
GII77_RS08280	COG2340	Cysteine-rich secretory protein family
GII77_RS08285	COG0768	penicillin binding
GII77_RS08290	COG4191	Histidine kinase
GII77_RS08295	COG0436	Aminotransferase
GII77_RS08305	COG0784	Response regulator, receiver
GII77_RS08305	COG0835	chemotaxis
GII77_RS08315	COG2814	Major facilitator Superfamily
GII77_RS08320	COG1376	ErfK ybiS ycfS ynhG family protein
GII77_RS08325	COG1408	metallophosphoesterase
GII77_RS08330	COG1028	Short-chain dehydrogenase reductase Sdr
GII77_RS08335	COG3409	Peptidoglycan-binding domain 1 protein
GII77_RS08345	COG2200	EAL domain
GII77_RS08355	COG4703	Protein of unknown function (DUF1797)
GII77_RS08360	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
GII77_RS08370	COG0517	IMP dehydrogenase activity
GII77_RS08375	COG0583	DNA-binding transcription factor activity
GII77_RS08380	COG0716	FMN binding
GII77_RS08390	COG0716	FMN binding
GII77_RS08395	COG2171	N-acyltransferase activity
GII77_RS08400	COG1473	amidohydrolase
GII77_RS08410	COG0668	transmembrane transport
GII77_RS08415	COG0450	alkyl hydroperoxide reductase
GII77_RS08420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII77_RS08435	COG0746	molybdenum cofactor guanylyltransferase activity
GII77_RS08440	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GII77_RS08445	COG0303	'Molybdopterin
GII77_RS08450	COG1763	Mo-molybdopterin cofactor biosynthetic process
GII77_RS08455	COG0314	molybdopterin synthase activity
GII77_RS08460	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GII77_RS08465	COG1132	(ABC) transporter
GII77_RS08470	COG1132	(ABC) transporter
GII77_RS08480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GII77_RS08485	COG1136	(ABC) transporter
GII77_RS08490	COG0577	efflux transmembrane transporter activity
GII77_RS08495	COG1349	DNA-binding transcription factor activity
GII77_RS08500	COG1105	Belongs to the carbohydrate kinase PfkB family
GII77_RS08505	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII77_RS08505	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII77_RS08505	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII77_RS08510	COG0681	Belongs to the peptidase S26 family
GII77_RS08520	COG0488	(ABC) transporter
GII77_RS08525	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GII77_RS08530	COG2309	aminopeptidase activity
GII77_RS08540	COG1077	Cell shape determining protein MreB Mrl
GII77_RS08545	COG2002	toxin-antitoxin pair type II binding
GII77_RS08550	COG3852	Histidine kinase
GII77_RS08555	COG2105	PFAM AIG2 family protein
GII77_RS08555	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
GII77_RS08560	COG0569	domain protein
GII77_RS08565	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GII77_RS08570	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GII77_RS08575	COG5503	Protein of unknown function (DUF1447)
GII77_RS08580	COG0561	phosphatase activity
GII77_RS08585	COG0242	peptide deformylase activity
GII77_RS08595	COG0497	DNA recombination
GII77_RS08600	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GII77_RS08605	COG0022	dehydrogenase e1 component
GII77_RS08610	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII77_RS08615	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GII77_RS08620	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII77_RS08630	COG1982	Orn Lys Arg decarboxylase major
GII77_RS08635	COG4476	Belongs to the UPF0223 family
GII77_RS08640	COG4493	Belongs to the UPF0637 family
GII77_RS08650	COG0483	inositol monophosphate 1-phosphatase activity
GII77_RS08660	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GII77_RS08680	COG1595	DNA-templated transcription, initiation
GII77_RS08700	COG1217	gtp-binding protein TYPA
GII77_RS08710	COG4896	Protein conserved in bacteria
GII77_RS08720	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GII77_RS08725	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GII77_RS08730	COG2066	Belongs to the glutaminase family
GII77_RS08735	COG4838	Belongs to the UPF0358 family
GII77_RS08740	COG0772	Belongs to the SEDS family
GII77_RS08745	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GII77_RS08750	COG1612	heme a metabolic process
GII77_RS08755	COG0109	protoheme IX farnesyltransferase activity
GII77_RS08760	COG2010	Cytochrome c
GII77_RS08760	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GII77_RS08765	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GII77_RS08770	COG1845	cytochrome c oxidase, subunit III
GII77_RS08775	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GII77_RS08780	COG3336	cytochrome c oxidase
GII77_RS08790	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
GII77_RS08795	COG2340	Cysteine-rich secretory protein family
GII77_RS08810	COG3679	Belongs to the UPF0342 family
GII77_RS08815	COG4471	UPF0298 protein
GII77_RS08820	COG0742	ribosomal rna small subunit methyltransferase
GII77_RS08825	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GII77_RS08830	COG3314	Sporulation integral membrane protein YlbJ
GII77_RS08835	COG1752	Esterase of the alpha-beta hydrolase superfamily
GII77_RS08840	COG3480	Lon protease (S16) C-terminal proteolytic domain
GII77_RS08845	COG1323	Belongs to the UPF0348 family
GII77_RS08855	COG1399	metal-binding, possibly nucleic acid-binding protein
GII77_RS08870	COG0454	-acetyltransferase
GII77_RS08875	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GII77_RS08880	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
GII77_RS08885	COG2001	Belongs to the MraZ family
GII77_RS08890	COG0275	rRNA processing
GII77_RS08895	COG4839	cell division protein FtsL
GII77_RS08900	COG0768	penicillin binding
GII77_RS08905	COG0768	penicillin binding
GII77_RS08910	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GII77_RS08915	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GII77_RS08920	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GII77_RS08925	COG0772	Belongs to the SEDS family
GII77_RS08930	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GII77_RS08935	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GII77_RS08940	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GII77_RS08945	COG3879	Bacterial protein of unknown function (DUF881)
GII77_RS08950	COG3879	Bacterial protein of unknown function (DUF881)
GII77_RS08955	COG3856	small basic protein
GII77_RS08960	COG0849	cell division
GII77_RS08965	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GII77_RS08970	COG4412	M6 family metalloprotease domain protein
GII77_RS08970	COG1404	Belongs to the peptidase S8 family
GII77_RS08980	COG1191	sigma factor activity
GII77_RS08985	COG1191	sigma factor activity
GII77_RS08990	COG1119	ATPase activity
GII77_RS08995	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII77_RS09000	COG1873	PFAM PRC-barrel domain
GII77_RS09005	COG1496	oxidoreductase activity
GII77_RS09010	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GII77_RS09015	COG1799	cell septum assembly
GII77_RS09020	COG0762	integral membrane protein
GII77_RS09025	COG2302	S4 RNA-binding domain
GII77_RS09030	COG3599	regulation of cell shape
GII77_RS09035	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GII77_RS09040	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GII77_RS09045	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GII77_RS09050	COG0564	pseudouridine synthase activity
GII77_RS09055	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GII77_RS09060	COG2233	PERMEase
GII77_RS09065	COG0540	Belongs to the ATCase OTCase family
GII77_RS09070	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GII77_RS09075	COG0505	Belongs to the CarA family
GII77_RS09080	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GII77_RS09085	COG0543	2 iron, 2 sulfur cluster binding
GII77_RS09090	COG0167	dihydroorotate dehydrogenase activity
GII77_RS09095	COG0284	orotidine-5'-phosphate decarboxylase activity
GII77_RS09100	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GII77_RS09105	COG0175	sulfate reduction
GII77_RS09110	COG0306	phosphate transporter
GII77_RS09115	COG2046	Belongs to the sulfate adenylyltransferase family
GII77_RS09120	COG0529	Catalyzes the synthesis of activated sulfate
GII77_RS09125	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GII77_RS09130	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
GII77_RS09135	COG1648	precorrin-2 dehydrogenase activity
GII77_RS09140	COG1293	RNA-binding protein homologous to eukaryotic snRNP
GII77_RS09145	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GII77_RS09150	COG1561	YicC-like family, N-terminal region
GII77_RS09160	COG0194	GDP metabolic process
GII77_RS09165	COG1758	RNA polymerase activity
GII77_RS09170	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GII77_RS09175	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GII77_RS09180	COG0242	peptide deformylase activity
GII77_RS09185	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GII77_RS09190	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GII77_RS09190	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GII77_RS09195	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GII77_RS09200	COG0631	protein serine/threonine phosphatase activity
GII77_RS09205	COG0515	serine threonine protein kinase
GII77_RS09205	COG2815	serine threonine protein kinase
GII77_RS09210	COG1162	GTPase activity
GII77_RS09215	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GII77_RS09220	COG1564	THIamine pyrophosphokinase
GII77_RS09230	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GII77_RS09235	COG1302	Protein conserved in bacteria
GII77_RS09240	COG1461	Dihydroxyacetone kinase
GII77_RS09245	COG1760	l-serine dehydratase
GII77_RS09250	COG1760	l-serine dehydratase
GII77_RS09255	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GII77_RS09260	COG1349	DNA-binding transcription factor activity
GII77_RS09260	COG2050	protein possibly involved in aromatic compounds catabolism
GII77_RS09265	COG0416	fatty acid biosynthetic process
GII77_RS09270	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GII77_RS09275	COG1028	Short-chain dehydrogenase reductase Sdr
GII77_RS09285	COG0571	ribonuclease III activity
GII77_RS09290	COG1196	nuclear chromosome segregation
GII77_RS09295	COG0552	protein localization to endoplasmic reticulum
GII77_RS09305	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GII77_RS09310	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GII77_RS09315	COG0228	four-way junction DNA binding
GII77_RS09320	COG1837	Belongs to the UPF0109 family
GII77_RS09330	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GII77_RS09335	COG0336	Belongs to the RNA methyltransferase TrmD family
GII77_RS09340	COG0335	large ribosomal subunit rRNA binding
GII77_RS09345	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GII77_RS09350	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GII77_RS09360	COG2257	FlhB HrpN YscU SpaS Family
GII77_RS09365	COG0045	succinate-CoA ligase (ADP-forming) activity
GII77_RS09370	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GII77_RS09375	COG0758	DNA mediated transformation
GII77_RS09380	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GII77_RS09385	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GII77_RS09390	COG4974	Belongs to the 'phage' integrase family
GII77_RS09395	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GII77_RS09400	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GII77_RS09405	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GII77_RS09410	COG1815	bacterial-type flagellum-dependent cell motility
GII77_RS09415	COG1558	bacterial-type flagellum-dependent cell motility
GII77_RS09420	COG1677	Flagellar hook-basal body complex protein FliE
GII77_RS09425	COG1766	The M ring may be actively involved in energy transduction
GII77_RS09430	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GII77_RS09435	COG1317	bacterial-type flagellum organization
GII77_RS09440	COG1157	protein secretion by the type III secretion system
GII77_RS09445	COG2882	bacterial-type flagellum organization
GII77_RS09450	COG3334	PFAM MgtE intracellular
GII77_RS09455	COG3144	bacterial-type flagellum assembly
GII77_RS09460	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GII77_RS09465	COG4786	Flagellar basal body rod
GII77_RS09470	COG1582	Flagellar protein (FlbD)
GII77_RS09475	COG1580	Controls the rotational direction of flagella during chemotaxis
GII77_RS09480	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GII77_RS09485	COG1776	CheC inhibitor of MCP methylation
GII77_RS09485	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GII77_RS09490	COG2201	protein-glutamate methylesterase activity
GII77_RS09495	COG3190	flagellar
GII77_RS09500	COG1338	Plays a role in the flagellum-specific transport system
GII77_RS09505	COG1987	bacterial-type flagellum assembly
GII77_RS09510	COG1684	flagellar biosynthetic protein fliR
GII77_RS09515	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GII77_RS09520	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GII77_RS09525	COG1419	protein localization to endoplasmic reticulum
GII77_RS09530	COG0455	bacterial-type flagellum organization
GII77_RS09535	COG2201	protein-glutamate methylesterase activity
GII77_RS09540	COG0643	Histidine kinase
GII77_RS09540	COG2198	Histidine kinase
GII77_RS09545	COG0835	chemotaxis
GII77_RS09550	COG1776	CheC inhibitor of MCP methylation
GII77_RS09555	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GII77_RS09560	COG1191	sigma factor activity
GII77_RS09570	COG0052	Belongs to the universal ribosomal protein uS2 family
GII77_RS09575	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GII77_RS09580	COG0528	UMP kinase activity
GII77_RS09585	COG0233	cytoplasmic translational termination
GII77_RS09590	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GII77_RS09595	COG4589	Belongs to the CDS family
GII77_RS09600	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GII77_RS09605	COG0750	zinc metalloprotease
GII77_RS09610	COG0442	prolyl-tRNA aminoacylation
GII77_RS09615	COG2176	DNA-directed DNA polymerase activity
GII77_RS09620	COG0779	Required for maturation of 30S ribosomal subunits
GII77_RS09625	COG0195	Participates in both transcription termination and antitermination
GII77_RS09630	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GII77_RS09635	COG1358	cellular component organization or biogenesis
GII77_RS09640	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GII77_RS09645	COG1550	Protein conserved in bacteria
GII77_RS09650	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GII77_RS09655	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GII77_RS09660	COG0196	riboflavin kinase activity
GII77_RS09665	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GII77_RS09670	COG1185	polyribonucleotide nucleotidyltransferase activity
GII77_RS09675	COG0726	polysaccharide deacetylase
GII77_RS09680	COG0612	Peptidase, M16
GII77_RS09685	COG1873	PFAM PRC-barrel domain
GII77_RS09690	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GII77_RS09695	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GII77_RS09700	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GII77_RS09705	COG0527	aspartate kinase activity
GII77_RS09710	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GII77_RS09715	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GII77_RS09720	COG0740	serine-type endopeptidase activity
GII77_RS09730	COG1674	ftsk spoiiie
GII77_RS09730	COG4980	gas vesicle protein
GII77_RS09735	COG2188	Transcriptional regulator
GII77_RS09740	COG2814	Major facilitator Superfamily
GII77_RS09745	COG0612	Peptidase, M16
GII77_RS09750	COG0612	Peptidase, M16
GII77_RS09755	COG0300	oxidoreductase activity
GII77_RS09770	COG1426	Protein conserved in bacteria
GII77_RS09775	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GII77_RS09780	COG1058	Belongs to the CinA family
GII77_RS09780	COG1546	Belongs to the CinA family
GII77_RS09785	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GII77_RS09790	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GII77_RS09795	COG1418	mRNA catabolic process
GII77_RS09800	COG1692	metallophosphoesterase
GII77_RS09805	COG2359	stage V sporulation protein S
GII77_RS09810	COG1063	alcohol dehydrogenase
GII77_RS09815	COG0156	8-amino-7-oxononanoate synthase activity
GII77_RS09820	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GII77_RS09825	COG4550	Control of competence regulator ComK, YlbF/YmcA
GII77_RS09835	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GII77_RS09840	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GII77_RS09855	COG3226	Transcriptional regulator
GII77_RS09860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII77_RS09870	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GII77_RS09875	COG3321	synthase
GII77_RS09880	COG2070	2-Nitropropane dioxygenase
GII77_RS09880	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GII77_RS09885	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII77_RS09890	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GII77_RS09895	COG3425	synthase
GII77_RS09900	COG1024	Enoyl-CoA hydratase
GII77_RS09905	COG1024	Enoyl-CoA hydratase
GII77_RS09910	COG1028	Short-chain dehydrogenase reductase Sdr
GII77_RS09910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII77_RS09910	COG0318	PFAM AMP-dependent synthetase and ligase
GII77_RS09910	COG0300	oxidoreductase activity
GII77_RS09910	COG3321	synthase
GII77_RS09915	COG3321	synthase
GII77_RS09915	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII77_RS09915	COG4221	oxidoreductase activity
GII77_RS09915	COG0300	oxidoreductase activity
GII77_RS09920	COG3321	synthase
GII77_RS09920	COG1028	Short-chain dehydrogenase reductase Sdr
GII77_RS09920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII77_RS09920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII77_RS09920	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII77_RS09925	COG1028	Short-chain dehydrogenase reductase Sdr
GII77_RS09925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII77_RS09925	COG4221	oxidoreductase activity
GII77_RS09925	COG3321	synthase
GII77_RS09930	COG3321	synthase
GII77_RS09930	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GII77_RS09930	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GII77_RS09930	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII77_RS09935	COG2124	cytochrome p450
GII77_RS09945	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII77_RS09950	COG1404	Belongs to the peptidase S8 family
GII77_RS09960	COG4195	phage-related replication protein
GII77_RS09965	COG1764	response to oxidative stress
GII77_RS09970	COG2076	Multidrug Resistance protein
GII77_RS09975	COG2076	Multidrug Resistance protein
GII77_RS09990	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GII77_RS09995	COG1923	regulation of RNA biosynthetic process
GII77_RS10010	COG1780	Probably involved in ribonucleotide reductase function
GII77_RS10015	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GII77_RS10020	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GII77_RS10025	COG4112	unkown
GII77_RS10030	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII77_RS10035	COG0464	growth
GII77_RS10040	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GII77_RS10045	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
GII77_RS10050	COG0789	Transcriptional regulator
GII77_RS10055	COG0174	glutamine synthetase
GII77_RS10075	COG4282	regulation of fungal-type cell wall biogenesis
GII77_RS10085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII77_RS10105	COG3655	Transcriptional regulator
GII77_RS10120	COG0135	phosphoribosylanthranilate isomerase activity
GII77_RS10125	COG2211	Major facilitator Superfamily
GII77_RS10130	COG3507	Belongs to the glycosyl hydrolase 43 family
GII77_RS10135	COG1940	carbohydrate kinase activity
GII77_RS10140	COG2115	Belongs to the xylose isomerase family
GII77_RS10145	COG1070	Carbohydrate kinase
GII77_RS10155	COG1525	nuclease
GII77_RS10160	COG2814	Major facilitator Superfamily
GII77_RS10165	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GII77_RS10175	COG0756	dUTP diphosphatase activity
GII77_RS10215	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GII77_RS10230	COG3832	glyoxalase III activity
GII77_RS10240	COG0697	spore germination
GII77_RS10245	COG0531	amino acid
GII77_RS10275	COG4195	phage-related replication protein
GII77_RS10285	COG0346	lactoylglutathione lyase activity
GII77_RS10290	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GII77_RS10295	COG1388	LysM domain
GII77_RS10300	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GII77_RS10305	COG4224	UPF0291 protein
GII77_RS10310	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GII77_RS10320	COG3763	UPF0154 protein
GII77_RS10330	COG0785	Cytochrome C biogenesis protein
GII77_RS10335	COG2201	protein-glutamate methylesterase activity
GII77_RS10340	COG4846	Membrane protein involved in cytochrome C biogenesis
GII77_RS10350	COG0071	Belongs to the small heat shock protein (HSP20) family
GII77_RS10365	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GII77_RS10370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII77_RS10390	COG0824	Thioesterase
GII77_RS10400	COG4841	protein insertion into membrane
GII77_RS10405	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GII77_RS10410	COG1832	CoA-binding protein
GII77_RS10415	COG0187	DNA topoisomerase II activity
GII77_RS10420	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GII77_RS10430	COG1115	amino acid carrier protein
GII77_RS10435	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
GII77_RS10445	COG5520	Belongs to the glycosyl hydrolase 30 family
GII77_RS10450	COG3507	Belongs to the glycosyl hydrolase 43 family
GII77_RS10455	COG2246	polysaccharide biosynthetic process
GII77_RS10460	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GII77_RS10465	COG0586	Pfam SNARE associated Golgi protein
GII77_RS10470	COG2404	hydrolase activity, acting on ester bonds
GII77_RS10475	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GII77_RS10480	COG1024	Enoyl-CoA hydratase
GII77_RS10485	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GII77_RS10490	COG0511	ligase activity, forming carbon-carbon bonds
GII77_RS10495	COG0439	Biotin carboxylase
GII77_RS10500	COG0318	PFAM AMP-dependent synthetase and ligase
GII77_RS10505	COG1960	acyl-CoA dehydrogenase activity
GII77_RS10515	COG1649	PFAM Uncharacterised BCR, COG1649
GII77_RS10525	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII77_RS10525	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GII77_RS10530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII77_RS10535	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII77_RS10540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII77_RS10545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII77_RS10550	COG2027	D-alanyl-D-alanine carboxypeptidase
GII77_RS10555	COG2017	converts alpha-aldose to the beta-anomer
GII77_RS10560	COG0534	Mate efflux family protein
GII77_RS10575	COG0582	viral genome integration into host DNA
GII77_RS10580	COG0166	Belongs to the GPI family
GII77_RS10585	COG0405	Gamma-glutamyltransferase
GII77_RS10590	COG0583	DNA-binding transcription factor activity
GII77_RS10595	COG0604	alcohol dehydrogenase
GII77_RS10600	COG0493	'glutamate synthase
GII77_RS10605	COG0067	glutamate synthase
GII77_RS10605	COG0069	glutamate synthase activity
GII77_RS10605	COG0070	glutamate synthase
GII77_RS10610	COG0583	DNA-binding transcription factor activity
GII77_RS10615	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GII77_RS10620	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII77_RS10630	COG0300	oxidoreductase activity
GII77_RS10635	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GII77_RS10645	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII77_RS10660	COG1131	(ABC) transporter
GII77_RS10670	COG2814	Major facilitator Superfamily
GII77_RS10675	COG1070	Carbohydrate kinase
GII77_RS10680	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GII77_RS10685	COG0243	molybdopterin cofactor binding
GII77_RS10715	COG0840	transmembrane signaling receptor activity
GII77_RS10715	COG5278	phosphoserine phosphatase activity
GII77_RS10720	COG2368	4-hydroxyphenylacetate
GII77_RS10725	COG4305	rare lipoprotein A
GII77_RS10730	COG3619	membrane
GII77_RS10735	COG3866	Pectate lyase
GII77_RS10740	COG2135	peptidase activity
GII77_RS10750	COG2140	Oxalate decarboxylase
GII77_RS10765	COG0456	acetyltransferase
GII77_RS10785	COG2720	vancomycin resistance protein
GII77_RS10795	COG3655	Transcriptional regulator
GII77_RS10800	COG3739	integral membrane protein
GII77_RS10805	COG0583	DNA-binding transcription factor activity
GII77_RS10810	COG0697	spore germination
GII77_RS10820	COG0693	protein deglycase activity
GII77_RS10825	COG2367	Beta-lactamase
GII77_RS10845	COG0574	Belongs to the PEP-utilizing enzyme family
GII77_RS10845	COG3848	Pyruvate phosphate dikinase
GII77_RS10850	COG0726	polysaccharide deacetylase
GII77_RS10860	COG2314	TM2 domain
GII77_RS10865	COG1396	sequence-specific DNA binding
GII77_RS10905	COG2723	6-phospho-beta-galactosidase activity
GII77_RS10920	COG0395	ABC-type sugar transport system, permease component
GII77_RS10925	COG1175	transmembrane transport
GII77_RS10935	COG1940	carbohydrate kinase activity
GII77_RS10950	COG5444	nuclease activity
GII77_RS10955	COG4282	regulation of fungal-type cell wall biogenesis
GII77_RS10960	COG1231	oxidoreductase activity
GII77_RS10965	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII77_RS10970	COG0662	Cupin 2, conserved barrel domain protein
GII77_RS10970	COG2207	Transcriptional regulator
GII77_RS10975	COG0456	acetyltransferase
GII77_RS10980	COG1309	transcriptional regulator
GII77_RS10985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII77_RS10990	COG3708	Transcriptional regulator
GII77_RS10995	COG2378	regulation of single-species biofilm formation
GII77_RS11005	COG0640	Transcriptional regulator
GII77_RS11010	COG0741	lytic transglycosylase activity
GII77_RS11015	COG2322	membrane
GII77_RS11030	COG1619	proteins homologs of microcin C7 resistance protein MccF
GII77_RS11035	COG3239	Fatty acid desaturase
GII77_RS11040	COG4585	Histidine kinase
GII77_RS11045	COG2197	response regulator
GII77_RS11050	COG1388	LysM domain
GII77_RS11050	COG3584	3D domain protein
GII77_RS11055	COG0514	ATP-dependent DNA helicase (RecQ)
GII77_RS11065	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GII77_RS11070	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GII77_RS11085	COG0071	Belongs to the small heat shock protein (HSP20) family
GII77_RS11110	COG1012	belongs to the aldehyde dehydrogenase family
GII77_RS11115	COG1657	PFAM Prenyltransferase squalene oxidase
GII77_RS11120	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GII77_RS11125	COG0733	neurotransmitter:sodium symporter activity
GII77_RS11130	COG0385	Bile acid
GII77_RS11135	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII77_RS11140	COG0567	Dehydrogenase, E1 component
GII77_RS11145	COG4548	von Willebrand factor, type A
GII77_RS11150	COG0714	Associated with various cellular activities
GII77_RS11155	COG2032	superoxide dismutase activity
GII77_RS11160	COG0791	NLP P60 protein
GII77_RS11160	COG1388	LysM domain
GII77_RS11165	COG1819	glycosyl
GII77_RS11170	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GII77_RS11175	COG0534	Mate efflux family protein
GII77_RS11180	COG1366	Belongs to the anti-sigma-factor antagonist family
GII77_RS11185	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GII77_RS11190	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GII77_RS11200	COG2962	Rard protein
GII77_RS11215	COG2610	gluconate transmembrane transporter activity
GII77_RS11220	COG1942	4-Oxalocrotonate Tautomerase
GII77_RS11225	COG1733	regulation of RNA biosynthetic process
GII77_RS11230	COG0778	Nitroreductase
GII77_RS11235	COG0400	carboxylic ester hydrolase activity
GII77_RS11240	COG0346	lactoylglutathione lyase activity
GII77_RS11250	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII77_RS11255	COG3409	Peptidoglycan-binding domain 1 protein
GII77_RS11255	COG0793	Belongs to the peptidase S41A family
GII77_RS11260	COG2226	methyltransferase
GII77_RS11270	COG1876	peptidase activity
GII77_RS11275	COG0813	purine-nucleoside phosphorylase activity
GII77_RS11290	COG0671	phosphoesterase, PA-phosphatase related
GII77_RS11310	COG4479	Belongs to the UPF0346 family
GII77_RS11320	COG1509	lysine 2,3-aminomutase activity
GII77_RS11325	COG0456	acetyltransferase
GII77_RS11330	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII77_RS11335	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GII77_RS11340	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GII77_RS11345	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GII77_RS11360	COG0456	acetyltransferase
GII77_RS11365	COG0463	Glycosyl transferase, family 2
GII77_RS11380	COG4641	Protein conserved in bacteria
GII77_RS11385	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
GII77_RS11390	COG1086	Polysaccharide biosynthesis protein
GII77_RS11395	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GII77_RS11400	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GII77_RS11405	COG1846	Transcriptional regulator
GII77_RS11410	COG0534	Mate efflux family protein
GII77_RS11420	COG4698	Protein conserved in bacteria
GII77_RS11425	COG2755	lipolytic protein G-D-S-L family
GII77_RS11430	COG1999	signal sequence binding
GII77_RS11440	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GII77_RS11445	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GII77_RS11450	COG1272	protein, Hemolysin III
GII77_RS11455	COG0204	Acyl-transferase
GII77_RS11460	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GII77_RS11465	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GII77_RS11470	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GII77_RS11480	COG2521	methyltransferase
GII77_RS11480	COG2136	Putative SAM-dependent methyltransferase
GII77_RS11490	COG0129	dihydroxy-acid dehydratase activity
GII77_RS11495	COG1413	lyase activity
GII77_RS11500	COG1418	mRNA catabolic process
GII77_RS11505	COG0386	Belongs to the glutathione peroxidase family
GII77_RS11510	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GII77_RS11515	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GII77_RS11525	COG1278	Cold shock
GII77_RS11545	COG0328	RNA-DNA hybrid ribonuclease activity
GII77_RS11550	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GII77_RS11555	COG0328	RNA-DNA hybrid ribonuclease activity
GII77_RS11565	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GII77_RS11580	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GII77_RS11590	COG1755	Isoprenylcysteine carboxyl methyltransferase
GII77_RS11595	COG3424	synthase
GII77_RS11600	COG2233	PERMEase
GII77_RS11605	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GII77_RS11610	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GII77_RS11620	COG0800	Aldolase
GII77_RS11625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII77_RS11630	COG1609	Transcriptional regulator
GII77_RS11635	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
GII77_RS11640	COG1028	Short-chain dehydrogenase reductase Sdr
GII77_RS11645	COG1199	ATP-dependent helicase activity
GII77_RS11665	COG0116	Belongs to the methyltransferase superfamily
GII77_RS11680	COG4474	Belongs to the UPF0398 family
GII77_RS11695	COG3359	exonuclease
GII77_RS11700	COG1205	dead DEAH box helicase
GII77_RS11700	COG1111	helicase
GII77_RS11705	COG2190	(PTS) system
GII77_RS11710	COG0071	Belongs to the small heat shock protein (HSP20) family
GII77_RS11745	COG3331	DNA recombination
GII77_RS11750	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII77_RS11750	COG4499	WXG100 protein secretion system (Wss), protein YukC
GII77_RS11760	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GII77_RS11765	COG3935	DnaD domain protein
GII77_RS11770	COG0017	Asparaginyl-tRNA synthetase
GII77_RS11775	COG0436	Aminotransferase
GII77_RS11780	COG5353	protein conserved in bacteria
GII77_RS11790	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GII77_RS11790	COG1199	ATP-dependent helicase activity
GII77_RS11795	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GII77_RS11800	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GII77_RS11805	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GII77_RS11810	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GII77_RS11810	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GII77_RS11815	COG0617	tRNA 3'-terminal CCA addition
GII77_RS11820	COG0438	transferase activity, transferring glycosyl groups
GII77_RS11825	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GII77_RS11830	COG1803	Methylglyoxal synthase
GII77_RS11835	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GII77_RS11840	COG1694	Mazg nucleotide pyrophosphohydrolase
GII77_RS11845	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII77_RS11855	COG4347	Protein of unknown function (DUF1405)
GII77_RS11860	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GII77_RS11860	COG2010	Cytochrome c
GII77_RS11865	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GII77_RS11870	COG0723	plastoquinol--plastocyanin reductase activity
GII77_RS11880	COG5582	Belongs to the UPF0302 family
GII77_RS11885	COG0457	Tetratricopeptide repeat
GII77_RS11890	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GII77_RS11895	COG0287	Prephenate dehydrogenase
GII77_RS11900	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GII77_RS11905	COG0159	tryptophan synthase activity
GII77_RS11910	COG0133	tryptophan synthase activity
GII77_RS11915	COG0135	phosphoribosylanthranilate isomerase activity
GII77_RS11925	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GII77_RS11930	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GII77_RS11935	COG4401	Chorismate mutase type I
GII77_RS11940	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GII77_RS11945	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GII77_RS11950	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GII77_RS11955	COG0105	UTP biosynthetic process
GII77_RS11960	COG0142	geranyltranstransferase activity
GII77_RS11965	COG2226	methyltransferase
GII77_RS11970	COG0142	geranyltranstransferase activity
GII77_RS11980	COG0302	gtp cyclohydrolase
GII77_RS11985	COG0776	regulation of translation
GII77_RS11990	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GII77_RS12005	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GII77_RS12010	COG1160	GTP binding
GII77_RS12035	COG1304	FMN binding
GII77_RS12040	COG0539	negative regulation of cytoplasmic translation
GII77_RS12045	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GII77_RS12055	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
GII77_RS12060	COG2959	enzyme of heme biosynthesis
GII77_RS12065	COG3773	Cell wall hydrolase
GII77_RS12065	COG3409	Peptidoglycan-binding domain 1 protein
GII77_RS12070	COG2339	peptidase activity
GII77_RS12075	COG0492	ferredoxin-NADP+ reductase activity
GII77_RS12080	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GII77_RS12085	COG4862	establishment of competence for transformation
GII77_RS12090	COG1408	metallophosphoesterase
GII77_RS12100	COG1388	LysM domain
GII77_RS12105	COG1266	CAAX protease self-immunity
GII77_RS12110	COG0514	ATP-dependent DNA helicase (RecQ)
GII77_RS12115	COG4955	Helix-turn-helix domain
GII77_RS12120	COG1141	Ferredoxin
GII77_RS12125	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GII77_RS12130	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GII77_RS12135	COG0710	3-dehydroquinate dehydratase activity
GII77_RS12145	COG1595	DNA-templated transcription, initiation
GII77_RS12150	COG5002	protein histidine kinase activity
GII77_RS12155	COG0745	RESPONSE REGULATOR receiver
GII77_RS12160	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GII77_RS12165	COG1333	cytochrome c biogenesis protein
GII77_RS12170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII77_RS12175	COG1187	pseudouridine synthase activity
GII77_RS12180	COG0700	Nucleoside recognition
GII77_RS12185	COG2715	membrane protein required for spore maturation
GII77_RS12190	COG1686	Belongs to the peptidase S11 family
GII77_RS12200	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GII77_RS12205	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GII77_RS12210	COG1547	Domain of unknown function (DUF309)
GII77_RS12215	COG0456	acetyltransferase
GII77_RS12220	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GII77_RS12225	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GII77_RS12225	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GII77_RS12230	COG0307	riboflavin synthase, alpha
GII77_RS12235	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GII77_RS12235	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GII77_RS12245	COG0681	Belongs to the peptidase S26 family
GII77_RS12255	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
GII77_RS12280	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GII77_RS12285	COG4086	secreted protein
GII77_RS12290	COG0019	diaminopimelate decarboxylase activity
GII77_RS12295	COG0697	spore germination
GII77_RS12310	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GII77_RS12330	COG1191	sigma factor activity
GII77_RS12335	COG2172	sigma factor antagonist activity
GII77_RS12340	COG1366	Belongs to the anti-sigma-factor antagonist family
GII77_RS12345	COG1686	Belongs to the peptidase S11 family
GII77_RS12350	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GII77_RS12355	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GII77_RS12360	COG4974	Belongs to the 'phage' integrase family
GII77_RS12370	COG0735	belongs to the Fur family
GII77_RS12375	COG1300	Membrane
GII77_RS12385	COG0281	malic enzyme
GII77_RS12390	COG1757	Na H antiporter
GII77_RS12395	COG1027	Aspartate ammonia-lyase
GII77_RS12400	COG0252	asparaginase activity
GII77_RS12405	COG1396	sequence-specific DNA binding
GII77_RS12410	COG1379	DNA repair
GII77_RS12415	COG0494	nUDIX hydrolase
GII77_RS12425	COG0667	Aldo Keto reductase
GII77_RS12435	COG1073	alpha beta
GII77_RS12445	COG4918	Iron-sulphur cluster biosynthesis
GII77_RS12450	COG0456	acetyltransferase
GII77_RS12450	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GII77_RS12455	COG2329	Antibiotic biosynthesis monooxygenase
GII77_RS12460	COG0456	acetyltransferase
GII77_RS12470	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GII77_RS12480	COG2211	Major facilitator Superfamily
GII77_RS12485	COG0346	lactoylglutathione lyase activity
GII77_RS12490	COG1072	(Pantothenic acid kinase))
GII77_RS12495	COG3048	D-serine ammonia-lyase activity
GII77_RS12500	COG0300	oxidoreductase activity
GII77_RS12505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII77_RS12510	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII77_RS12515	COG4187	Peptidase family M20/M25/M40
GII77_RS12520	COG1902	pentaerythritol trinitrate reductase activity
GII77_RS12525	COG0596	Alpha beta hydrolase
GII77_RS12535	COG1234	tRNA 3'-trailer cleavage
GII77_RS12540	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GII77_RS12545	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GII77_RS12550	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GII77_RS12560	COG0706	membrane insertase activity
GII77_RS12565	COG3361	conserved protein (COG2071)
GII77_RS12570	COG2195	Cleaves the N-terminal amino acid of tripeptides
GII77_RS12575	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GII77_RS12580	COG0346	lactoylglutathione lyase activity
GII77_RS12590	COG1376	ErfK ybiS ycfS ynhG family protein
GII77_RS12595	COG4129	membrane
GII77_RS12600	COG1126	abc transporter atp-binding protein
GII77_RS12605	COG0765	amino acid transport
GII77_RS12610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII77_RS12620	COG1597	lipid kinase activity
GII77_RS12625	COG2814	Major facilitator Superfamily
GII77_RS12630	COG4978	Transcriptional regulator
GII77_RS12630	COG0789	Transcriptional regulator
GII77_RS12635	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII77_RS12640	COG0022	dehydrogenase e1 component
GII77_RS12645	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GII77_RS12650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GII77_RS12655	COG3426	butyrate kinase activity
GII77_RS12660	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GII77_RS12665	COG0280	phosphate acetyltransferase
GII77_RS12670	COG3829	transcription factor binding
GII77_RS12670	COG3290	protein histidine kinase activity
GII77_RS12680	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GII77_RS12685	COG2079	MmgE PrpD family protein
GII77_RS12690	COG0372	Belongs to the citrate synthase family
GII77_RS12695	COG1960	acyl-CoA dehydrogenase activity
GII77_RS12700	COG1250	3-hydroxyacyl-CoA dehydrogenase
GII77_RS12705	COG0183	Belongs to the thiolase family
GII77_RS12710	COG0584	glycerophosphoryl diester phosphodiesterase
GII77_RS12715	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII77_RS12730	COG1902	pentaerythritol trinitrate reductase activity
GII77_RS12735	COG0745	RESPONSE REGULATOR receiver
GII77_RS12740	COG0750	zinc metalloprotease
GII77_RS12745	COG0497	DNA recombination
GII77_RS12750	COG1438	arginine binding
GII77_RS12755	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GII77_RS12760	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GII77_RS12765	COG0142	geranyltranstransferase activity
GII77_RS12770	COG1722	exodeoxyribonuclease VII activity
GII77_RS12775	COG1570	exodeoxyribonuclease VII activity
GII77_RS12780	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GII77_RS12785	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GII77_RS12790	COG1302	Protein conserved in bacteria
GII77_RS12795	COG0439	Biotin carboxylase
GII77_RS12800	COG0511	ligase activity, forming carbon-carbon bonds
GII77_RS12840	COG3854	ATPases associated with a variety of cellular activities
GII77_RS12850	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GII77_RS12855	COG0006	proline dipeptidase activity
GII77_RS12860	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GII77_RS12870	COG3872	metal-dependent enzyme
GII77_RS12880	COG1752	Esterase of the alpha-beta hydrolase superfamily
GII77_RS12885	COG1321	iron dependent repressor
GII77_RS12890	COG0095	Lipoate-protein ligase
GII77_RS12895	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII77_RS12900	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GII77_RS12905	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GII77_RS12910	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GII77_RS12915	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GII77_RS12930	COG1396	sequence-specific DNA binding
GII77_RS12940	COG0681	Belongs to the peptidase S26 family
GII77_RS12965	COG4940	Competence protein ComGF
GII77_RS12975	COG4970	Tfp pilus assembly protein FimT
GII77_RS12980	COG4537	Required for transformation and DNA binding
GII77_RS12985	COG1459	type II secretion system
GII77_RS12990	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GII77_RS12995	COG0517	IMP dehydrogenase activity
GII77_RS13000	COG0598	Magnesium transport protein CorA
GII77_RS13005	COG1253	flavin adenine dinucleotide binding
GII77_RS13010	COG1366	Belongs to the anti-sigma-factor antagonist family
GII77_RS13020	COG1393	Belongs to the ArsC family
GII77_RS13030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII77_RS13040	COG0011	TIGRFAM Protein of
GII77_RS13050	COG2866	Carboxypeptidase
GII77_RS13055	COG1368	sulfuric ester hydrolase activity
GII77_RS13060	COG1940	carbohydrate kinase activity
GII77_RS13065	COG4483	Protein conserved in bacteria
GII77_RS13070	COG0457	Tetratricopeptide repeat
GII77_RS13070	COG0705	Rhomboid family
GII77_RS13080	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GII77_RS13090	COG0438	transferase activity, transferring glycosyl groups
GII77_RS13105	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GII77_RS13110	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GII77_RS13115	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GII77_RS13120	COG0581	inorganic phosphate transmembrane transporter activity
GII77_RS13125	COG0573	inorganic phosphate transmembrane transporter activity
GII77_RS13130	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GII77_RS13135	COG0768	penicillin binding
GII77_RS13140	COG0477	Major facilitator Superfamily
GII77_RS13145	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GII77_RS13150	COG2839	Protein conserved in bacteria
GII77_RS13155	COG5521	maltodextrose utilization protein MalA
GII77_RS13165	COG1388	LysM domain
GII77_RS13170	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GII77_RS13175	COG4709	membrane
GII77_RS13180	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
GII77_RS13185	COG0735	belongs to the Fur family
GII77_RS13190	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII77_RS13200	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GII77_RS13205	COG0513	Belongs to the DEAD box helicase family
GII77_RS13215	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GII77_RS13220	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GII77_RS13225	COG2384	SAM-dependent methyltransferase
GII77_RS13230	COG2010	Cytochrome c
GII77_RS13235	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GII77_RS13240	COG0358	DNA primase activity
GII77_RS13245	COG1671	Belongs to the UPF0178 family
GII77_RS13250	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GII77_RS13255	COG0517	IMP dehydrogenase activity
GII77_RS13260	COG0751	glycine-tRNA ligase activity
GII77_RS13265	COG0752	glycyl-tRNA synthetase alpha subunit
GII77_RS13270	COG1381	Involved in DNA repair and RecF pathway recombination
GII77_RS13280	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GII77_RS13285	COG0295	cytidine deaminase activity
GII77_RS13290	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GII77_RS13295	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GII77_RS13300	COG1480	7TM receptor with intracellular HD hydrolase
GII77_RS13305	COG1702	phosphate starvation-inducible protein PhoH
GII77_RS13310	COG0561	phosphatase activity
GII77_RS13325	COG4864	UPF0365 protein
GII77_RS13330	COG1030	water channel activity
GII77_RS13335	COG1610	YqeY-like protein
GII77_RS13345	COG1283	sodium-dependent phosphate transmembrane transporter activity
GII77_RS13350	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GII77_RS13355	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GII77_RS13360	COG2264	protein methyltransferase activity
GII77_RS13365	COG0484	heat shock protein binding
GII77_RS13370	COG0443	Heat shock 70 kDa protein
GII77_RS13375	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GII77_RS13380	COG1420	regulation of RNA biosynthetic process
GII77_RS13385	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GII77_RS13390	COG0481	GTPase activity
GII77_RS13400	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII77_RS13405	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GII77_RS13410	COG0268	Binds directly to 16S ribosomal RNA
GII77_RS13415	COG1466	dna polymerase III delta subunit
GII77_RS13430	COG0658	competence protein
GII77_RS13430	COG2333	competence protein COMEC
GII77_RS13435	COG2131	deaminase
GII77_RS13440	COG1555	photosystem II stabilization
GII77_RS13440	COG1596	polysaccharide export
GII77_RS13445	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII77_RS13450	COG2226	methyltransferase
GII77_RS13455	COG0799	negative regulation of ribosome biogenesis
GII77_RS13460	COG1713	HD superfamily hydrolase involved in NAD metabolism
GII77_RS13465	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GII77_RS13470	COG1534	Rna-binding protein
GII77_RS13475	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GII77_RS13480	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GII77_RS13485	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GII77_RS13495	COG2755	lipolytic protein G-D-S-L family
GII77_RS13500	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII77_RS13500	COG3409	Peptidoglycan-binding domain 1 protein
GII77_RS13505	COG0398	Pfam SNARE associated Golgi protein
GII77_RS13510	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GII77_RS13520	COG3209	COG3209 Rhs family protein
GII77_RS13535	COG0477	Major facilitator Superfamily
GII77_RS13540	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GII77_RS13545	COG4124	Belongs to the glycosyl hydrolase 26 family
GII77_RS13550	COG0457	Tetratricopeptide repeat
GII77_RS13570	COG5444	nuclease activity
GII77_RS13585	COG1309	transcriptional regulator
GII77_RS13595	COG1388	LysM domain
GII77_RS13595	COG3409	Peptidoglycan-binding domain 1 protein
GII77_RS13595	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII77_RS13655	COG0563	adenylate kinase activity
GII77_RS13660	COG2856	Zn peptidase
GII77_RS13675	COG5002	protein histidine kinase activity
GII77_RS13675	COG0642	Histidine kinase
GII77_RS13680	COG0745	RESPONSE REGULATOR receiver
GII77_RS13685	COG2311	Membrane
GII77_RS13695	COG0454	-acetyltransferase
GII77_RS13700	COG2249	NAD(P)H dehydrogenase (quinone) activity
GII77_RS13710	COG0730	response to heat
GII77_RS13715	COG0425	Belongs to the sulfur carrier protein TusA family
GII77_RS13720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII77_RS13720	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII77_RS13730	COG0425	Belongs to the sulfur carrier protein TusA family
GII77_RS13730	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII77_RS13735	COG2210	Belongs to the sulfur carrier protein TusA family
GII77_RS13740	COG1937	Protein conserved in bacteria
GII77_RS13745	COG0662	Cupin 2, conserved barrel domain protein
GII77_RS13755	COG4978	Transcriptional regulator
GII77_RS13755	COG0789	Transcriptional regulator
GII77_RS13760	COG2814	Major facilitator Superfamily
GII77_RS13765	COG0456	acetyltransferase
GII77_RS13770	COG1253	flavin adenine dinucleotide binding
GII77_RS13780	COG0697	spore germination
GII77_RS13785	COG0583	DNA-binding transcription factor activity
GII77_RS13790	COG2072	flavoprotein involved in K transport
GII77_RS13795	COG1230	cation diffusion facilitator family transporter
GII77_RS13800	COG1942	4-Oxalocrotonate Tautomerase
GII77_RS13805	COG0583	DNA-binding transcription factor activity
GII77_RS13815	COG1114	Component of the transport system for branched-chain amino acids
GII77_RS13820	COG1687	branched-chain amino acid
GII77_RS13825	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GII77_RS13830	COG1522	sequence-specific DNA binding
GII77_RS13835	COG2732	(Barnase) inhibitor
GII77_RS13840	COG2124	cytochrome p450
GII77_RS13845	COG1335	isochorismatase
GII77_RS13855	COG2318	DinB family
GII77_RS13865	COG2070	2-Nitropropane dioxygenase
GII77_RS13870	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GII77_RS13890	COG3443	Belongs to the bacterial solute-binding protein 9 family
GII77_RS13895	COG1595	DNA-templated transcription, initiation
GII77_RS13900	COG0667	Aldo Keto reductase
GII77_RS13905	COG2851	Citrate transporter
GII77_RS13910	COG0583	DNA-binding transcription factor activity
GII77_RS13915	COG2828	Protein conserved in bacteria
GII77_RS13920	COG3409	Peptidoglycan-binding domain 1 protein
GII77_RS13925	COG5566	PFAM Mor transcription activator
GII77_RS13930	COG0596	Alpha beta hydrolase
GII77_RS13935	COG4991	sh3 domain protein
GII77_RS13940	COG4991	sh3 domain protein
GII77_RS13950	COG0346	lactoylglutathione lyase activity
GII77_RS13960	COG5577	PFAM Coat F domain
GII77_RS13965	COG1063	alcohol dehydrogenase
GII77_RS13975	COG5577	PFAM Coat F domain
GII77_RS13980	COG0789	Transcriptional regulator
GII77_RS13990	COG1064	alcohol dehydrogenase
GII77_RS13995	COG0693	protein deglycase activity
GII77_RS14000	COG1621	beta-fructofuranosidase activity
GII77_RS14005	COG3716	PTS system mannose fructose sorbose family IID component
GII77_RS14010	COG3715	PTS system
GII77_RS14015	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII77_RS14020	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII77_RS14025	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GII77_RS14025	COG3933	PFAM sigma-54 factor interaction domain-containing protein
GII77_RS14035	COG1113	amino acid transport
GII77_RS14040	COG1280	lysine exporter protein (LysE YggA)
GII77_RS14045	COG1378	Sugar-specific transcriptional regulator TrmB
GII77_RS14050	COG1595	DNA-templated transcription, initiation
GII77_RS14060	COG2755	lipolytic protein G-D-S-L family
GII77_RS14060	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GII77_RS14070	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GII77_RS14070	COG2124	cytochrome p450
GII77_RS14075	COG1309	transcriptional regulator
GII77_RS14080	COG2226	methyltransferase
GII77_RS14095	COG2116	formate transmembrane transporter activity
GII77_RS14100	COG5609	conserved protein (DUF2294)
GII77_RS14105	COG3383	formate dehydrogenase (NAD+) activity
GII77_RS14110	COG2427	Protein of unknown function (DUF1641)
GII77_RS14120	COG0626	cystathionine gamma-synthase activity
GII77_RS14125	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GII77_RS14130	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GII77_RS14135	COG2226	methyltransferase
GII77_RS14150	COG0768	penicillin binding
GII77_RS14155	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GII77_RS14160	COG0572	uridine kinase
GII77_RS14165	COG0826	peptidase U32
GII77_RS14170	COG0826	peptidase U32
GII77_RS14175	COG4122	O-methyltransferase activity
GII77_RS14180	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GII77_RS14185	COG3906	Belongs to the UPF0473 family
GII77_RS14190	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GII77_RS14195	COG4472	Bacterial protein of unknown function (DUF965)
GII77_RS14200	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GII77_RS14205	COG0628	permease
GII77_RS14210	COG1126	abc transporter atp-binding protein
GII77_RS14215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII77_RS14220	COG0765	amino acid transport
GII77_RS14225	COG0765	amino acid transport
GII77_RS14240	COG3881	PFAM PRC-barrel domain
GII77_RS14245	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GII77_RS14250	COG0457	Tetratricopeptide repeat
GII77_RS14255	COG0482	sulfurtransferase activity
GII77_RS14260	COG1104	cysteine desulfurase activity
GII77_RS14265	COG1959	2 iron, 2 sulfur cluster binding
GII77_RS14270	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GII77_RS14275	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GII77_RS14285	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GII77_RS14290	COG0124	histidyl-tRNA synthetase
GII77_RS14300	COG3103	Sh3 type 3 domain protein
GII77_RS14300	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII77_RS14300	COG4991	sh3 domain protein
GII77_RS14305	COG1490	D-aminoacyl-tRNA deacylase activity
GII77_RS14310	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GII77_RS14315	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GII77_RS14320	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GII77_RS14320	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GII77_RS14325	COG5416	Lipopolysaccharide assembly protein A domain
GII77_RS14330	COG0490	domain, Protein
GII77_RS14335	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GII77_RS14335	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GII77_RS14345	COG2244	polysaccharide biosynthetic process
GII77_RS14350	COG2323	membrane
GII77_RS14360	COG1862	Preprotein translocase
GII77_RS14365	COG0343	queuine tRNA-ribosyltransferase activity
GII77_RS14370	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GII77_RS14380	COG2255	four-way junction helicase activity
GII77_RS14385	COG0632	four-way junction helicase activity
GII77_RS14395	COG2814	Major facilitator Superfamily
GII77_RS14400	COG0673	inositol 2-dehydrogenase activity
GII77_RS14405	COG2112	serine threonine protein kinase
GII77_RS14425	COG1115	amino acid carrier protein
GII77_RS14430	COG0217	transcriptional regulatory protein
GII77_RS14440	COG1388	LysM domain
GII77_RS14445	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GII77_RS14450	COG0157	Belongs to the NadC ModD family
GII77_RS14455	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GII77_RS14460	COG1104	cysteine desulfurase activity
GII77_RS14465	COG1827	regulation of RNA biosynthetic process
GII77_RS14470	COG0077	Prephenate dehydratase
GII77_RS14475	COG4492	Belongs to the UPF0735 family
GII77_RS14480	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GII77_RS14485	COG3290	protein histidine kinase activity
GII77_RS14495	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GII77_RS14500	COG2868	ribosomal protein
GII77_RS14505	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GII77_RS14510	COG1994	Peptidase M50
GII77_RS14515	COG0739	heme binding
GII77_RS14520	COG2894	cell division
GII77_RS14525	COG0850	regulation of cytokinetic process
GII77_RS14530	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GII77_RS14540	COG1077	Cell shape determining protein MreB Mrl
GII77_RS14545	COG2003	Belongs to the UPF0758 family
GII77_RS14550	COG0424	maF-like protein
GII77_RS14560	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GII77_RS14565	COG0285	dihydrofolate synthase activity
GII77_RS14570	COG0525	valine-tRNA ligase activity
GII77_RS14580	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII77_RS14585	COG1388	LysM domain
GII77_RS14590	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GII77_RS14595	COG0113	porphobilinogen synthase activity
GII77_RS14600	COG1587	Uroporphyrinogen-III synthase
GII77_RS14605	COG0181	hydroxymethylbilane synthase activity
GII77_RS14610	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GII77_RS14615	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GII77_RS14625	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GII77_RS14630	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GII77_RS14635	COG1067	ATP-dependent peptidase activity
GII77_RS14635	COG0470	DNA polymerase III
GII77_RS14640	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GII77_RS14645	COG0544	peptidyl-prolyl cis-trans isomerase activity
GII77_RS14650	COG0457	Tetratricopeptide repeat
GII77_RS14650	COG1477	protein flavinylation
GII77_RS14655	COG0066	3-isopropylmalate dehydratase activity
GII77_RS14660	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GII77_RS14665	COG0473	3-isopropylmalate dehydrogenase activity
GII77_RS14670	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GII77_RS14675	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GII77_RS14680	COG0440	acetolactate synthase activity
GII77_RS14685	COG0028	Belongs to the TPP enzyme family
GII77_RS14695	COG0454	-acetyltransferase
GII77_RS14700	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
GII77_RS14710	COG0622	Phosphoesterase
GII77_RS14715	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GII77_RS14720	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GII77_RS14725	COG5401	PFAM Sporulation and spore germination
GII77_RS14730	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GII77_RS14735	COG1846	Transcriptional regulator
GII77_RS14740	COG2197	response regulator
GII77_RS14745	COG0824	Thioesterase
GII77_RS14750	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GII77_RS14755	COG1053	succinate dehydrogenase
GII77_RS14760	COG2009	succinate dehydrogenase
GII77_RS14765	COG1719	4-vinyl reductase, 4VR
GII77_RS14770	COG0527	aspartate kinase activity
GII77_RS14775	COG0322	excinuclease ABC activity
GII77_RS14780	COG3118	belongs to the thioredoxin family
GII77_RS14785	COG3534	alpha-L-arabinofuranosidase
GII77_RS14790	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GII77_RS14795	COG2086	electron transfer activity
GII77_RS14800	COG1024	Enoyl-CoA hydratase
GII77_RS14805	COG1309	transcriptional regulator
GII77_RS14810	COG0318	PFAM AMP-dependent synthetase and ligase
GII77_RS14815	COG3766	membrane
GII77_RS14820	COG1193	negative regulation of DNA recombination
GII77_RS14825	COG1796	DNA polymerase
GII77_RS14825	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GII77_RS14830	COG1286	toxin biosynthetic process
GII77_RS14835	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GII77_RS14840	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GII77_RS14845	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII77_RS14845	COG0072	phenylalanine-tRNA ligase activity
GII77_RS14850	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GII77_RS14860	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GII77_RS14870	COG3835	regulator
GII77_RS14875	COG0277	FAD linked oxidase domain protein
GII77_RS14880	COG0247	lactate metabolic process
GII77_RS14885	COG0346	lactoylglutathione lyase activity
GII77_RS14895	COG1966	Carbon starvation protein
GII77_RS14900	COG3534	alpha-L-arabinofuranosidase
GII77_RS14905	COG0395	ABC-type sugar transport system, permease component
GII77_RS14910	COG1175	transmembrane transport
GII77_RS14915	COG1653	transport
GII77_RS14920	COG0371	Dehydrogenase
GII77_RS14925	COG0647	UMP catabolic process
GII77_RS14930	COG0235	Class ii aldolase
GII77_RS14935	COG1069	ribulokinase activity
GII77_RS14940	COG2160	L-arabinose isomerase activity
GII77_RS14945	COG3507	Belongs to the glycosyl hydrolase 43 family
GII77_RS14950	COG1363	Peptidase, m42
GII77_RS14960	COG3326	Membrane
GII77_RS14965	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GII77_RS14970	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GII77_RS14975	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GII77_RS14985	COG1346	cytolysis
GII77_RS14990	COG1380	Effector of murein hydrolase LrgA
GII77_RS14995	COG3279	Response regulator of the LytR AlgR family
GII77_RS15000	COG3275	phosphorelay sensor kinase activity
GII77_RS15005	COG1011	Hydrolase
GII77_RS15010	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GII77_RS15020	COG0398	Pfam SNARE associated Golgi protein
GII77_RS15025	COG1484	DNA-dependent DNA replication
GII77_RS15030	COG3611	Membrane attachment protein
GII77_RS15035	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GII77_RS15040	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GII77_RS15045	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GII77_RS15050	COG1733	regulation of RNA biosynthetic process
GII77_RS15055	COG2814	Major facilitator Superfamily
GII77_RS15060	COG0656	L-ascorbic acid biosynthetic process
GII77_RS15065	COG0237	dephospho-CoA kinase activity
GII77_RS15070	COG1971	Probably functions as a manganese efflux pump
GII77_RS15075	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GII77_RS15080	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GII77_RS15080	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GII77_RS15085	COG5002	protein histidine kinase activity
GII77_RS15090	COG0745	RESPONSE REGULATOR receiver
GII77_RS15095	COG0039	L-malate dehydrogenase activity
GII77_RS15100	COG0538	isocitrate dehydrogenase activity
GII77_RS15105	COG0372	Belongs to the citrate synthase family
GII77_RS15110	COG2707	UPF0756 membrane protein
GII77_RS15115	COG0628	permease
GII77_RS15120	COG3030	protein affecting phage T7 exclusion by the F plasmid
GII77_RS15125	COG0469	pyruvate kinase activity
GII77_RS15130	COG0205	6-phosphofructokinase activity
GII77_RS15135	COG0825	malonyl-CoA metabolic process
GII77_RS15140	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GII77_RS15145	COG0281	malic enzyme
GII77_RS15150	COG0587	DNA-directed DNA polymerase activity
GII77_RS15170	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GII77_RS15180	COG4109	DRTGG domain
GII77_RS15185	COG0730	response to heat
GII77_RS15190	COG1473	amidohydrolase
GII77_RS15195	COG0196	riboflavin kinase activity
GII77_RS15200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII77_RS15205	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GII77_RS15210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII77_RS15215	COG1126	abc transporter atp-binding protein
GII77_RS15220	COG0765	amino acid transport
GII77_RS15225	COG0765	amino acid transport
GII77_RS15230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII77_RS15235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII77_RS15240	COG0454	-acetyltransferase
GII77_RS15245	COG0583	DNA-binding transcription factor activity
GII77_RS15250	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GII77_RS15255	COG1028	Short-chain dehydrogenase reductase Sdr
GII77_RS15265	COG0165	Argininosuccinate lyase
GII77_RS15270	COG0137	argininosuccinate synthase activity
GII77_RS15275	COG0521	Mo-molybdopterin cofactor biosynthetic process
GII77_RS15280	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GII77_RS15290	COG0827	DNA restriction-modification system
GII77_RS15295	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GII77_RS15300	COG3874	Sporulation protein YtfJ
GII77_RS15310	COG1714	RDD family
GII77_RS15315	COG0616	signal peptide processing
GII77_RS15320	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GII77_RS15325	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GII77_RS15330	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GII77_RS15340	COG0301	tRNA thio-modification
GII77_RS15345	COG1104	cysteine desulfurase activity
GII77_RS15350	COG1114	Component of the transport system for branched-chain amino acids
GII77_RS15355	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GII77_RS15360	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GII77_RS15365	COG1309	transcriptional regulator
GII77_RS15370	COG1956	GAF domain-containing protein
GII77_RS15375	COG2199	diguanylate cyclase activity
GII77_RS15375	COG2203	Gaf domain
GII77_RS15385	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GII77_RS15390	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GII77_RS15395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GII77_RS15400	COG0454	-acetyltransferase
GII77_RS15405	COG0517	IMP dehydrogenase activity
GII77_RS15410	COG0123	including yeast histone deacetylase and acetoin utilization protein
GII77_RS15415	COG1360	Flagellar Motor Protein
GII77_RS15420	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GII77_RS15425	COG1609	Transcriptional regulator
GII77_RS15430	COG1605	Chorismate mutase
GII77_RS15430	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GII77_RS15435	COG3118	belongs to the thioredoxin family
GII77_RS15440	COG4980	gas vesicle protein
GII77_RS15445	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GII77_RS15450	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GII77_RS15455	COG1674	ftsk spoiiie
GII77_RS15460	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII77_RS15465	COG4848	Belongs to the UPF0354 family
GII77_RS15470	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII77_RS15485	COG1363	Peptidase, m42
GII77_RS15490	COG5584	Small secreted protein
GII77_RS15495	COG0281	malic enzyme
GII77_RS15500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII77_RS15505	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GII77_RS15515	COG0510	thiamine kinase activity
GII77_RS15520	COG1523	belongs to the glycosyl hydrolase 13 family
GII77_RS15525	COG1597	lipid kinase activity
GII77_RS15535	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GII77_RS15540	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GII77_RS15545	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII77_RS15550	COG2252	PERMEase
GII77_RS15555	COG4473	ABC transporter
GII77_RS15560	COG1131	(ABC) transporter
GII77_RS15565	COG1349	DNA-binding transcription factor activity
GII77_RS15570	COG1187	pseudouridine synthase activity
GII77_RS15575	COG2244	polysaccharide biosynthetic process
GII77_RS15580	COG2081	HI0933 family
GII77_RS15585	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GII77_RS15595	COG5578	integral membrane protein
GII77_RS15600	COG0673	inositol 2-dehydrogenase activity
GII77_RS15605	COG1653	transport
GII77_RS15610	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GII77_RS15615	COG4209	transmembrane transport
GII77_RS15620	COG2207	Transcriptional regulator
GII77_RS15625	COG1653	transport
GII77_RS15630	COG0395	ABC-type sugar transport system, permease component
GII77_RS15635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII77_RS15640	COG2124	cytochrome p450
GII77_RS15645	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GII77_RS15655	COG0156	8-amino-7-oxononanoate synthase activity
GII77_RS15660	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GII77_RS15670	COG1073	alpha beta
GII77_RS15675	COG1609	Transcriptional regulator
GII77_RS15680	COG1653	transport
GII77_RS15685	COG1175	transmembrane transport
GII77_RS15690	COG0395	ABC-type sugar transport system, permease component
GII77_RS15695	COG1486	melibiose metabolic process
GII77_RS15700	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII77_RS15705	COG0495	leucyl-tRNA aminoacylation
GII77_RS15715	COG2202	Pas domain
GII77_RS15715	COG1366	Belongs to the anti-sigma-factor antagonist family
GII77_RS15720	COG2814	Major facilitator Superfamily
GII77_RS15730	COG0577	efflux transmembrane transporter activity
GII77_RS15735	COG1136	(ABC) transporter
GII77_RS15740	COG2205	protein histidine kinase activity
GII77_RS15745	COG0745	RESPONSE REGULATOR receiver
GII77_RS15750	COG0577	efflux transmembrane transporter activity
GII77_RS15755	COG1136	(ABC) transporter
GII77_RS15770	COG1131	(ABC) transporter
GII77_RS15775	COG1725	Transcriptional regulator
GII77_RS15790	COG1242	4 iron, 4 sulfur cluster binding
GII77_RS15795	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GII77_RS15805	COG2267	carboxylic ester hydrolase activity
GII77_RS15810	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GII77_RS15815	COG1113	amino acid transport
GII77_RS15820	COG0367	asparagine synthase
GII77_RS15825	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GII77_RS15830	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GII77_RS15840	COG1506	peptidase
GII77_RS15845	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GII77_RS15850	COG1116	anion transmembrane transporter activity
GII77_RS15855	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GII77_RS15860	COG0494	nUDIX hydrolase
GII77_RS15865	COG4824	toxin secretion phage lysis holin
GII77_RS15870	COG0783	Belongs to the Dps family
GII77_RS15885	COG1854	S-ribosylhomocysteine lyase activity
GII77_RS15890	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GII77_RS15895	COG0288	reversible hydration of carbon dioxide
GII77_RS15900	COG0254	rRNA binding
GII77_RS15905	COG1271	oxidase subunit
GII77_RS15910	COG1294	oxidase, subunit
GII77_RS15920	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GII77_RS15925	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GII77_RS15925	COG1321	iron dependent repressor
GII77_RS15930	COG1121	(ABC) transporter
GII77_RS15935	COG0803	Belongs to the bacterial solute-binding protein 9 family
GII77_RS15940	COG4948	Mandelate Racemase Muconate Lactonizing
GII77_RS15945	COG0318	PFAM AMP-dependent synthetase and ligase
GII77_RS15950	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GII77_RS15955	COG0596	Alpha beta hydrolase
GII77_RS15960	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GII77_RS15965	COG1169	isochorismate synthase
GII77_RS15970	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GII77_RS15975	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GII77_RS15980	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GII77_RS15985	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII77_RS15990	COG0438	transferase activity, transferring glycosyl groups
GII77_RS16000	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII77_RS16005	COG0438	transferase activity, transferring glycosyl groups
GII77_RS16010	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII77_RS16020	COG0058	SHG alpha-glucan phosphorylase activity
GII77_RS16025	COG0297	glycogen (starch) synthase activity
GII77_RS16030	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GII77_RS16035	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GII77_RS16040	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GII77_RS16165	COG3859	Proton-coupled thiamine transporter YuaJ
GII77_RS16170	COG1247	-acetyltransferase
GII77_RS16175	COG2268	Band 7 protein
GII77_RS16180	COG1585	Membrane protein implicated in regulation of membrane protease activity
GII77_RS16185	COG2318	DinB family
GII77_RS16195	COG1454	alcohol dehydrogenase
GII77_RS16200	COG1012	belongs to the aldehyde dehydrogenase family
GII77_RS16205	COG1510	regulation of RNA biosynthetic process
GII77_RS16215	COG0569	domain protein
GII77_RS16220	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GII77_RS16225	COG4682	membrane
GII77_RS16230	COG1705	Flagellar rod assembly protein muramidase FlgJ
GII77_RS16235	COG0477	Major facilitator Superfamily
GII77_RS16240	COG5553	Cysteine dioxygenase type I
GII77_RS16250	COG1968	undecaprenyl-diphosphatase activity
GII77_RS16255	COG0628	permease
GII77_RS16260	COG0673	inositol 2-dehydrogenase activity
GII77_RS16265	COG4806	L-rhamnose isomerase
GII77_RS16270	COG3254	rhamnose metabolic process
GII77_RS16275	COG1070	Carbohydrate kinase
GII77_RS16280	COG1349	DNA-binding transcription factor activity
GII77_RS16285	COG1028	Short-chain dehydrogenase reductase Sdr
GII77_RS16285	COG3347	Dehydrogenase
GII77_RS16290	COG0840	transmembrane signaling receptor activity
GII77_RS16295	COG0840	transmembrane signaling receptor activity
GII77_RS16300	COG0840	transmembrane signaling receptor activity
GII77_RS16305	COG0840	transmembrane signaling receptor activity
GII77_RS16320	COG0432	Pfam Uncharacterised protein family UPF0047
GII77_RS16330	COG0366	Alpha amylase catalytic
GII77_RS16335	COG1253	flavin adenine dinucleotide binding
GII77_RS16340	COG2738	Putative neutral zinc metallopeptidase
GII77_RS16355	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GII77_RS16370	COG0166	Belongs to the GPI family
GII77_RS16375	COG1979	alcohol dehydrogenase
GII77_RS16380	COG1979	alcohol dehydrogenase
GII77_RS16385	COG2155	Conserved Protein
GII77_RS16390	COG1098	S1 RNA binding domain
GII77_RS16395	COG0436	Aminotransferase
GII77_RS16400	COG1522	sequence-specific DNA binding
GII77_RS16405	COG2267	carboxylic ester hydrolase activity
GII77_RS16415	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GII77_RS16420	COG2205	protein histidine kinase activity
GII77_RS16430	COG5018	Exonuclease
GII77_RS16440	COG2814	Major facilitator Superfamily
GII77_RS16445	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII77_RS16450	COG3011	Protein conserved in bacteria
GII77_RS16460	COG3290	protein histidine kinase activity
GII77_RS16465	COG4565	transcriptional regulatory protein
GII77_RS16470	COG1744	ABC transporter substrate-binding protein PnrA-like
GII77_RS16475	COG3845	ABC transporter
GII77_RS16480	COG4603	Belongs to the binding-protein-dependent transport system permease family
GII77_RS16485	COG1079	Belongs to the binding-protein-dependent transport system permease family
GII77_RS16490	COG3493	citrate carrier protein
GII77_RS16500	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GII77_RS16500	COG2111	Na H antiporter
GII77_RS16505	COG2111	Na H antiporter
GII77_RS16510	COG1006	Multisubunit Na H antiporter MnhC subunit
GII77_RS16515	COG0651	ATP synthesis coupled electron transport
GII77_RS16520	COG1863	multisubunit Na H antiporter MnhE subunit
GII77_RS16525	COG2212	antiporter activity
GII77_RS16530	COG1320	monovalent cation:proton antiporter activity
GII77_RS16535	COG2050	protein possibly involved in aromatic compounds catabolism
GII77_RS16540	COG2197	response regulator
GII77_RS16545	COG4585	Histidine kinase
GII77_RS16555	COG0142	geranyltranstransferase activity
GII77_RS16575	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GII77_RS16580	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GII77_RS16585	COG1335	isochorismatase
GII77_RS16590	COG5506	Protein of unknown function (DUF1694)
GII77_RS16605	COG0628	permease
GII77_RS16620	COG1418	mRNA catabolic process
GII77_RS16625	COG1028	Short-chain dehydrogenase reductase Sdr
GII77_RS16635	COG1511	domain protein
GII77_RS16640	COG1674	ftsk spoiiie
GII77_RS16640	COG0433	COG0433 Predicted ATPase
GII77_RS16645	COG4499	WXG100 protein secretion system (Wss), protein YukC
GII77_RS16650	COG5417	Belongs to the EsaB family
GII77_RS16655	COG4842	Belongs to the WXG100 family
GII77_RS16660	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GII77_RS16660	COG2508	Transcriptional regulator
GII77_RS16665	COG0686	Belongs to the AlaDH PNT family
GII77_RS16670	COG5634	Uncharacterized conserved protein (DUF2278)
GII77_RS16675	COG3251	PFAM MbtH domain protein
GII77_RS16680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII77_RS16685	COG1535	isochorismatase
GII77_RS16685	COG3433	isochorismatase activity
GII77_RS16690	COG1021	2,3-dihydroxybenzoate-AMP ligase
GII77_RS16695	COG1169	isochorismate synthase
GII77_RS16700	COG1028	Short-chain dehydrogenase reductase Sdr
GII77_RS16705	COG2819	hydrolase of the alpha beta superfamily
GII77_RS16710	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GII77_RS16715	COG1268	BioY protein
GII77_RS16720	COG2056	Na+-H+ antiporter family
GII77_RS16725	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GII77_RS16730	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
GII77_RS16735	COG3584	3D domain protein
GII77_RS16750	COG1252	NADH dehydrogenase
GII77_RS16755	COG0492	ferredoxin-NADP+ reductase activity
GII77_RS16765	COG0516	GMP reductase activity
GII77_RS16770	COG2808	Putative FMN-binding domain
GII77_RS16775	COG0456	acetyltransferase
GII77_RS16780	COG0316	Belongs to the HesB IscA family
GII77_RS16785	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GII77_RS16790	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GII77_RS16795	COG4844	belongs to the
GII77_RS16800	COG1252	NADH dehydrogenase
GII77_RS16805	COG4837	Protein of unknown function (DUF1462)
GII77_RS16810	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GII77_RS16815	COG0823	Involved in the tonB-independent uptake of proteins
GII77_RS16815	COG4946	Tricorn protease homolog
GII77_RS16815	COG1506	peptidase
GII77_RS16820	COG0083	homoserine kinase activity
GII77_RS16825	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GII77_RS16830	COG0460	homoserine dehydrogenase
GII77_RS16835	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII77_RS16840	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GII77_RS16845	COG0647	UMP catabolic process
GII77_RS16850	COG2445	Protein of unknown function DUF86
GII77_RS16855	COG4470	Protein conserved in bacteria
GII77_RS16865	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GII77_RS16870	COG0739	heme binding
GII77_RS16880	COG3377	Domain of unknown function (DUF1805)
GII77_RS16885	COG0737	Belongs to the 5'-nucleotidase family
GII77_RS16890	COG0730	response to heat
GII77_RS16895	COG1801	Protein of unknown function DUF72
GII77_RS16905	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GII77_RS16910	COG2508	Transcriptional regulator
GII77_RS16915	COG2233	PERMEase
GII77_RS16920	COG2233	PERMEase
GII77_RS16930	COG2351	hydroxyisourate hydrolase activity
GII77_RS16940	COG2080	2 iron, 2 sulfur cluster binding
GII77_RS16945	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GII77_RS16950	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GII77_RS16955	COG2068	MobA-Related Protein
GII77_RS16960	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GII77_RS16965	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GII77_RS16970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII77_RS16980	COG2356	endonuclease I
GII77_RS16985	COG3842	ATPase activity
GII77_RS16990	COG2188	Transcriptional regulator
GII77_RS16995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII77_RS17000	COG0395	ABC-type sugar transport system, permease component
GII77_RS17005	COG1175	transmembrane transport
GII77_RS17010	COG1653	transport
GII77_RS17015	COG2222	sugar isomerase
GII77_RS17020	COG0322	excinuclease ABC activity
GII77_RS17025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GII77_RS17040	COG0346	lactoylglutathione lyase activity
GII77_RS17045	COG0640	Transcriptional regulator
GII77_RS17050	COG0719	Fe-S assembly protein
GII77_RS17055	COG0822	iron-sulfur transferase activity
GII77_RS17060	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GII77_RS17065	COG0719	Fe-S assembly protein
GII77_RS17070	COG0396	ATPase activity
GII77_RS17080	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GII77_RS17085	COG1464	Belongs to the NlpA lipoprotein family
GII77_RS17090	COG2011	ABC-type metal ion transport system permease component
GII77_RS17095	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GII77_RS17105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII77_RS17110	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GII77_RS17120	COG0509	glycine decarboxylation via glycine cleavage system
GII77_RS17125	COG1393	Belongs to the ArsC family
GII77_RS17130	COG1960	acyl-CoA dehydrogenase activity
GII77_RS17135	COG0183	Belongs to the thiolase family
GII77_RS17140	COG1024	Enoyl-CoA hydratase
GII77_RS17140	COG1250	3-hydroxyacyl-CoA dehydrogenase
GII77_RS17160	COG5577	PFAM Coat F domain
GII77_RS17165	COG1846	Transcriptional regulator
GII77_RS17170	COG0477	Major facilitator Superfamily
GII77_RS17175	COG1942	4-Oxalocrotonate Tautomerase
GII77_RS17180	COG1028	Short-chain dehydrogenase reductase Sdr
GII77_RS17185	COG0583	DNA-binding transcription factor activity
GII77_RS17195	COG1120	ATPase activity
GII77_RS17210	COG1028	Short-chain dehydrogenase reductase Sdr
GII77_RS17215	COG0783	Belongs to the Dps family
GII77_RS17220	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII77_RS17225	COG0745	RESPONSE REGULATOR receiver
GII77_RS17230	COG2205	protein histidine kinase activity
GII77_RS17230	COG2770	Histidine kinase
GII77_RS17240	COG1309	transcriptional regulator
GII77_RS17245	COG0114	fumarate hydratase activity
GII77_RS17255	COG0697	spore germination
GII77_RS17260	COG0814	amino acid
GII77_RS17270	COG2197	response regulator
GII77_RS17275	COG4585	Histidine kinase
GII77_RS17280	COG4758	membrane
GII77_RS17285	COG3595	metallopeptidase activity
GII77_RS17290	COG1842	Phage shock protein A
GII77_RS17295	COG4758	membrane
GII77_RS17300	COG2814	Major facilitator Superfamily
GII77_RS17305	COG2096	Adenosyltransferase
GII77_RS17310	COG1120	ATPase activity
GII77_RS17315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII77_RS17320	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII77_RS17325	COG1028	Short-chain dehydrogenase reductase Sdr
GII77_RS17330	COG3386	PFAM SMP-30 Gluconolaconase
GII77_RS17335	COG2205	protein histidine kinase activity
GII77_RS17340	COG0745	RESPONSE REGULATOR receiver
GII77_RS17350	COG1191	sigma factor activity
GII77_RS17360	COG2140	Oxalate decarboxylase
GII77_RS17370	COG0577	efflux transmembrane transporter activity
GII77_RS17375	COG1136	(ABC) transporter
GII77_RS17380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GII77_RS17385	COG1120	ATPase activity
GII77_RS17390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII77_RS17395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII77_RS17400	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII77_RS17405	COG0531	amino acid
GII77_RS17415	COG1988	membrane-bound metal-dependent
GII77_RS17420	COG1368	sulfuric ester hydrolase activity
GII77_RS17425	COG1910	domain protein
GII77_RS17430	COG0725	ABC transporter, periplasmic molybdate-binding protein
GII77_RS17435	COG4149	molybdate abc transporter
GII77_RS17440	COG0656	L-ascorbic acid biosynthetic process
GII77_RS17450	COG0025	NhaP-type Na H and K H
GII77_RS17455	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GII77_RS17460	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GII77_RS17465	COG3973	AAA domain
GII77_RS17475	COG2860	membrane
GII77_RS17480	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GII77_RS17485	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GII77_RS17490	COG2217	Heavy metal translocating P-type atpase
GII77_RS17495	COG2217	Heavy metal translocating P-type atpase
GII77_RS17500	COG2608	mercury ion transmembrane transporter activity
GII77_RS17505	COG1937	Protein conserved in bacteria
GII77_RS17510	COG0673	inositol 2-dehydrogenase activity
GII77_RS17515	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GII77_RS17520	COG1289	transmembrane transporter activity
GII77_RS17530	COG2076	Multidrug Resistance protein
GII77_RS17535	COG1309	transcriptional regulator
GII77_RS17540	COG1028	Short-chain dehydrogenase reductase Sdr
GII77_RS17550	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GII77_RS17555	COG0557	exoribonuclease II activity
GII77_RS17560	COG1647	Serine aminopeptidase, S33
GII77_RS17565	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GII77_RS17570	COG0596	Alpha beta hydrolase
GII77_RS17575	COG1476	TRANSCRIPTIONal
GII77_RS17580	COG1396	sequence-specific DNA binding
GII77_RS17585	COG1396	sequence-specific DNA binding
GII77_RS17590	COG1733	regulation of RNA biosynthetic process
GII77_RS17595	COG0840	transmembrane signaling receptor activity
GII77_RS17600	COG1174	glycine betaine transport
GII77_RS17605	COG1732	Glycine betaine
GII77_RS17610	COG1174	glycine betaine transport
GII77_RS17615	COG1125	glycine betaine transport
GII77_RS17615	COG0517	IMP dehydrogenase activity
GII77_RS17620	COG1510	regulation of RNA biosynthetic process
GII77_RS17640	COG5658	integral membrane protein
GII77_RS17645	COG0640	Transcriptional regulator
GII77_RS17650	COG1174	glycine betaine transport
GII77_RS17655	COG1732	Glycine betaine
GII77_RS17660	COG1174	glycine betaine transport
GII77_RS17665	COG0517	IMP dehydrogenase activity
GII77_RS17665	COG1125	glycine betaine transport
GII77_RS17670	COG1510	regulation of RNA biosynthetic process
GII77_RS17675	COG2095	MarC family integral membrane protein
GII77_RS17685	COG3064	Membrane
GII77_RS17690	COG4640	response to antibiotic
GII77_RS17695	COG0456	acetyltransferase
GII77_RS17700	COG0148	phosphopyruvate hydratase activity
GII77_RS17705	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GII77_RS17710	COG0149	triose-phosphate isomerase activity
GII77_RS17715	COG0126	phosphoglycerate kinase activity
GII77_RS17720	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GII77_RS17725	COG2390	Transcriptional regulator
GII77_RS17730	COG2814	Major facilitator Superfamily
GII77_RS17735	COG1609	Transcriptional regulator
GII77_RS17740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII77_RS17745	COG0583	DNA-binding transcription factor activity
GII77_RS17750	COG0697	spore germination
GII77_RS17755	COG1113	amino acid transport
GII77_RS17760	COG3858	chitin binding
GII77_RS17765	COG1556	Lactate utilization protein
GII77_RS17770	COG1139	Iron-sulfur cluster binding protein
GII77_RS17775	COG0247	lactate metabolic process
GII77_RS17780	COG2197	response regulator
GII77_RS17785	COG4585	Histidine kinase
GII77_RS17790	COG0842	Transport permease protein
GII77_RS17795	COG1131	(ABC) transporter
GII77_RS17800	COG0596	Alpha beta hydrolase
GII77_RS17805	COG2208	phosphoserine phosphatase activity
GII77_RS17810	COG3867	Arabinogalactan endo-beta-1,4-galactanase
GII77_RS17815	COG1874	Beta-galactosidase
GII77_RS17820	COG3833	ABC-type maltose transport systems, permease component
GII77_RS17825	COG1175	transmembrane transport
GII77_RS17830	COG2182	Extracellular solute-binding protein
GII77_RS17835	COG1609	Transcriptional regulator
GII77_RS17840	COG2186	Transcriptional regulator
GII77_RS17845	COG1620	l-lactate permease
GII77_RS17850	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GII77_RS17860	COG5039	Polysaccharide pyruvyl transferase
GII77_RS17865	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GII77_RS17870	COG0110	maltose O-acetyltransferase activity
GII77_RS17875	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GII77_RS17880	COG2244	polysaccharide biosynthetic process
GII77_RS17885	COG1216	Glycosyl transferase, family 2
GII77_RS17890	COG5039	Polysaccharide pyruvyl transferase
GII77_RS17895	COG1216	Glycosyl transferase, family 2
GII77_RS17905	COG0438	transferase activity, transferring glycosyl groups
GII77_RS17910	COG1215	transferase activity, transferring glycosyl groups
GII77_RS17915	COG0438	transferase activity, transferring glycosyl groups
GII77_RS17920	COG1086	Polysaccharide biosynthesis protein
GII77_RS17925	COG0489	protein tyrosine kinase activity
GII77_RS17930	COG3944	biosynthesis protein
GII77_RS17935	COG1396	sequence-specific DNA binding
GII77_RS17940	COG2272	Belongs to the type-B carboxylesterase lipase family
GII77_RS17950	COG3479	Phenolic acid decarboxylase
GII77_RS17960	COG1794	racemase activity, acting on amino acids and derivatives
GII77_RS17965	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GII77_RS17970	COG1621	beta-fructofuranosidase activity
GII77_RS17975	COG1621	beta-fructofuranosidase activity
GII77_RS17980	COG0531	amino acid
GII77_RS17985	COG1309	transcriptional regulator
GII77_RS17990	COG2076	Multidrug Resistance protein
GII77_RS17995	COG2076	Multidrug Resistance protein
GII77_RS18005	COG0277	FAD linked oxidase domain protein
GII77_RS18010	COG3621	Patatin-like phospholipase
GII77_RS18020	COG0740	serine-type endopeptidase activity
GII77_RS18025	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GII77_RS18030	COG0366	Alpha amylase catalytic
GII77_RS18035	COG1554	hydrolase, family 65, central catalytic
GII77_RS18040	COG5521	maltodextrose utilization protein MalA
GII77_RS18045	COG3833	ABC-type maltose transport systems, permease component
GII77_RS18050	COG1175	transmembrane transport
GII77_RS18055	COG2182	Extracellular solute-binding protein
GII77_RS18060	COG0366	Alpha amylase catalytic
GII77_RS18065	COG1609	Transcriptional regulator
GII77_RS18070	COG1611	Belongs to the LOG family
GII77_RS18075	COG1694	Mazg nucleotide pyrophosphohydrolase
GII77_RS18080	COG0659	secondary active sulfate transmembrane transporter activity
GII77_RS18085	COG0288	reversible hydration of carbon dioxide
GII77_RS18090	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GII77_RS18095	COG0577	efflux transmembrane transporter activity
GII77_RS18100	COG1136	(ABC) transporter
GII77_RS18105	COG5002	protein histidine kinase activity
GII77_RS18110	COG0745	RESPONSE REGULATOR receiver
GII77_RS18120	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GII77_RS18125	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII77_RS18130	COG1481	regulation of sporulation
GII77_RS18135	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GII77_RS18140	COG1660	Displays ATPase and GTPase activities
GII77_RS18145	COG1051	belongs to the nudix hydrolase family
GII77_RS18150	COG0492	ferredoxin-NADP+ reductase activity
GII77_RS18155	COG0791	NLP P60 protein
GII77_RS18155	COG3883	PFAM NLP P60 protein
GII77_RS18160	COG0457	Tetratricopeptide repeat
GII77_RS18165	COG1132	(ABC) transporter
GII77_RS18190	COG0140	phosphoribosyl-ATP diphosphatase activity
GII77_RS18190	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GII77_RS18195	COG0107	imidazoleglycerol-phosphate synthase activity
GII77_RS18200	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GII77_RS18205	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GII77_RS18210	COG0131	Imidazoleglycerol-phosphate dehydratase
GII77_RS18215	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GII77_RS18220	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GII77_RS18225	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GII77_RS18230	COG4990	cell redox homeostasis
GII77_RS18235	COG5297	Belongs to the glycosyl hydrolase family 6
GII77_RS18240	COG0110	maltose O-acetyltransferase activity
GII77_RS18245	COG0546	phosphoglycolate phosphatase activity
GII77_RS18250	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GII77_RS18255	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GII77_RS18260	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GII77_RS18265	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GII77_RS18270	COG0363	glucosamine-6-phosphate deaminase activity
GII77_RS18275	COG2188	Transcriptional regulator
GII77_RS18280	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GII77_RS18285	COG1846	Transcriptional regulator
GII77_RS18290	COG2124	cytochrome p450
GII77_RS18300	COG1846	Transcriptional regulator
GII77_RS18305	COG2814	Major facilitator Superfamily
GII77_RS18310	COG1950	PFAM Membrane protein of
GII77_RS18315	COG1983	PspC domain protein
GII77_RS18320	COG3595	metallopeptidase activity
GII77_RS18340	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GII77_RS18345	COG0556	nucleotide-excision repair
GII77_RS18350	COG4897	Protein conserved in bacteria
GII77_RS18355	COG0574	Belongs to the PEP-utilizing enzyme family
GII77_RS18355	COG3848	Pyruvate phosphate dikinase
GII77_RS18360	COG1309	transcriptional regulator
GII77_RS18365	COG2814	Major facilitator Superfamily
GII77_RS18370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII77_RS18380	COG0793	Belongs to the peptidase S41A family
GII77_RS18380	COG3409	Peptidoglycan-binding domain 1 protein
GII77_RS18385	COG2177	Part of the ABC transporter FtsEX involved in
GII77_RS18390	COG2884	Cell division ATP-binding protein ftsE
GII77_RS18395	COG2010	Cytochrome c
GII77_RS18400	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII77_RS18410	COG0653	protein targeting
GII77_RS18415	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GII77_RS18430	COG1516	flagellar protein fliS
GII77_RS18435	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GII77_RS18440	COG1334	flagellar protein FlaG
GII77_RS18445	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GII77_RS18450	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GII77_RS18455	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
GII77_RS18465	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GII77_RS18470	COG4786	Flagellar basal body rod
GII77_RS18470	COG1256	bacterial-type flagellum assembly
GII77_RS18475	COG3418	PFAM FlgN family protein
GII77_RS18480	COG2747	anti-sigma28 factor FlgM
GII77_RS18490	COG1040	competence protein
GII77_RS18500	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GII77_RS18505	COG1307	EDD domain protein, DegV family
GII77_RS18510	COG2197	response regulator
GII77_RS18515	COG4585	Histidine kinase
GII77_RS18520	COG1739	Uncharacterized protein family UPF0029
GII77_RS18525	COG1316	TRANSCRIPTIONal
GII77_RS18530	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GII77_RS18535	COG0438	transferase activity, transferring glycosyl groups
GII77_RS18540	COG1215	transferase activity, transferring glycosyl groups
GII77_RS18545	COG3206	protein involved in exopolysaccharide biosynthesis
GII77_RS18550	COG3307	-O-antigen
GII77_RS18555	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GII77_RS18560	COG0297	glycogen (starch) synthase activity
GII77_RS18560	COG0438	transferase activity, transferring glycosyl groups
GII77_RS18565	COG2244	polysaccharide biosynthetic process
GII77_RS18580	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII77_RS18580	COG2247	cell wall binding repeat
GII77_RS18585	COG2385	sporulation resulting in formation of a cellular spore
GII77_RS18585	COG2247	cell wall binding repeat
GII77_RS18595	COG1316	TRANSCRIPTIONal
GII77_RS18600	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GII77_RS18620	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GII77_RS18625	COG1134	teichoic acid transport
GII77_RS18630	COG1682	transport, permease protein
GII77_RS18635	COG1215	transferase activity, transferring glycosyl groups
GII77_RS18635	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GII77_RS18640	COG0463	Glycosyl transferase, family 2
GII77_RS18685	COG4193	domain, Protein
GII77_RS18690	COG1482	cell wall glycoprotein biosynthetic process
GII77_RS18695	COG0697	spore germination
GII77_RS18700	COG0814	amino acid
GII77_RS18710	COG2814	Major facilitator Superfamily
GII77_RS18715	COG1316	TRANSCRIPTIONal
GII77_RS18720	COG0561	phosphatase activity
GII77_RS18725	COG0791	NLP P60 protein
GII77_RS18735	COG2843	Capsule synthesis protein
GII77_RS18745	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GII77_RS18750	COG1609	Transcriptional regulator
GII77_RS18755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII77_RS18760	COG1869	D-ribose catabolic process
GII77_RS18765	COG1129	ABC transporter
GII77_RS18770	COG1172	Belongs to the binding-protein-dependent transport system permease family
GII77_RS18775	COG1879	ABC-type sugar transport system periplasmic component
GII77_RS18780	COG3103	Sh3 type 3 domain protein
GII77_RS18790	COG2249	NAD(P)H dehydrogenase (quinone) activity
GII77_RS18795	COG3527	Alpha-acetolactate decarboxylase
GII77_RS18800	COG0028	Belongs to the TPP enzyme family
GII77_RS18805	COG0583	DNA-binding transcription factor activity
GII77_RS18810	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GII77_RS18825	COG5337	Spore coat protein CotH
GII77_RS18835	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GII77_RS18845	COG0405	Gamma-glutamyltransferase
GII77_RS18850	COG1522	sequence-specific DNA binding
GII77_RS18855	COG2059	Chromate
GII77_RS18860	COG2059	Chromate
GII77_RS18870	COG0655	NAD(P)H dehydrogenase (quinone) activity
GII77_RS18875	COG0583	DNA-binding transcription factor activity
GII77_RS18890	COG5444	nuclease activity
GII77_RS18910	COG3878	Protein conserved in bacteria
GII77_RS18915	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GII77_RS18920	COG4464	protein tyrosine phosphatase activity
GII77_RS18925	COG0489	protein tyrosine kinase activity
GII77_RS18930	COG3944	biosynthesis protein
GII77_RS18940	COG4715	Zinc finger, swim domain protein
GII77_RS18945	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GII77_RS18950	COG0561	phosphatase activity
GII77_RS18955	COG1349	DNA-binding transcription factor activity
GII77_RS18960	COG0629	single-stranded DNA binding
GII77_RS18975	COG3764	Sortase (surface protein transpeptidase)
GII77_RS18985	COG3279	Response regulator of the LytR AlgR family
GII77_RS18990	COG0745	RESPONSE REGULATOR receiver
GII77_RS18990	COG2972	Histidine kinase
GII77_RS18995	COG1970	mechanosensitive ion channel activity
GII77_RS19000	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GII77_RS19005	COG0457	Tetratricopeptide repeat
GII77_RS19010	COG4786	Flagellar basal body rod
GII77_RS19015	COG4786	Flagellar basal body rod
GII77_RS19020	COG1077	Cell shape determining protein MreB Mrl
GII77_RS19025	COG1609	Transcriptional regulator
GII77_RS19035	COG1846	Transcriptional regulator
GII77_RS19040	COG2814	Major facilitator Superfamily
GII77_RS19045	COG3420	alginic acid biosynthetic process
GII77_RS19050	COG1953	Uracil, thiamine, allantoin
GII77_RS19055	COG0477	Major facilitator Superfamily
GII77_RS19060	COG1335	isochorismatase
GII77_RS19070	COG0004	ammonium transporteR
GII77_RS19075	COG0347	Belongs to the P(II) protein family
GII77_RS19080	COG0671	phosphoesterase, PA-phosphatase related
GII77_RS19105	COG0739	heme binding
GII77_RS19110	COG1247	-acetyltransferase
GII77_RS19130	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GII77_RS19135	COG0789	Transcriptional regulator
GII77_RS19145	COG2910	NAD(P)H-binding
GII77_RS19150	COG1959	2 iron, 2 sulfur cluster binding
GII77_RS19155	COG0804	urea catabolic process
GII77_RS19160	COG0832	Belongs to the urease beta subunit family
GII77_RS19165	COG0831	urea catabolic process
GII77_RS19180	COG3237	CsbD-like
GII77_RS19185	COG1994	Peptidase M50
GII77_RS19190	COG0457	Tetratricopeptide repeat
GII77_RS19195	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GII77_RS19200	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GII77_RS19210	COG2304	oxidoreductase activity
GII77_RS19220	COG2304	oxidoreductase activity
GII77_RS19225	COG2385	sporulation resulting in formation of a cellular spore
GII77_RS19230	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GII77_RS19240	COG4836	Membrane
GII77_RS19250	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GII77_RS19255	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GII77_RS19260	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GII77_RS19265	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GII77_RS19270	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GII77_RS19275	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GII77_RS19285	COG0356	it plays a direct role in the translocation of protons across the membrane
GII77_RS19295	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GII77_RS19300	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GII77_RS19305	COG4475	Protein of unknown function (DUF436)
GII77_RS19310	COG0698	ribose 5-phosphate isomerase
GII77_RS19315	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GII77_RS19320	COG1971	Probably functions as a manganese efflux pump
GII77_RS19325	COG0009	L-threonylcarbamoyladenylate synthase
GII77_RS19330	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GII77_RS19350	COG2890	protein-(glutamine-N5) methyltransferase activity
GII77_RS19355	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GII77_RS19360	COG0346	lactoylglutathione lyase activity
GII77_RS19365	COG0789	Transcriptional regulator
GII77_RS19370	COG0679	Auxin Efflux Carrier
GII77_RS19375	COG0281	malic enzyme
GII77_RS19380	COG1435	thymidine kinase activity
GII77_RS19390	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GII77_RS19400	COG1494	fructose-1,6-bisphosphatase
GII77_RS19405	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GII77_RS19410	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GII77_RS19415	COG0191	fructose-bisphosphate aldolase activity
GII77_RS19420	COG2204	response regulator
GII77_RS19425	COG4821	SIS domain
GII77_RS19430	COG0504	CTP synthase activity
GII77_RS19435	COG3343	RNA polymerase activity
GII77_RS19440	COG1960	acyl-CoA dehydrogenase activity
GII77_RS19445	COG2181	nitrate reductase activity
GII77_RS19445	COG0247	lactate metabolic process
GII77_RS19450	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GII77_RS19455	COG4294	response to UV
GII77_RS19465	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GII77_RS19470	COG1132	(ABC) transporter
GII77_RS19475	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GII77_RS19485	COG2181	nitrate reductase activity
GII77_RS19490	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GII77_RS19495	COG1140	nitrate reductase beta subunit
GII77_RS19500	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GII77_RS19505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GII77_RS19515	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GII77_RS19520	COG2223	nitrite transmembrane transporter activity
GII77_RS19525	COG0018	arginyl-trna synthetase
GII77_RS19530	COG4506	Protein conserved in bacteria
GII77_RS19545	COG0535	radical SAM domain protein
GII77_RS19555	COG1131	(ABC) transporter
GII77_RS19560	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GII77_RS19565	COG0612	Peptidase, M16
GII77_RS19570	COG0612	Peptidase, M16
GII77_RS19580	COG3391	amine dehydrogenase activity
GII77_RS19585	COG3391	amine dehydrogenase activity
GII77_RS19590	COG0457	Tetratricopeptide repeat
GII77_RS19605	COG0010	Belongs to the arginase family
GII77_RS19610	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GII77_RS19615	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII77_RS19625	COG1994	Peptidase M50
GII77_RS19630	COG1942	4-Oxalocrotonate Tautomerase
GII77_RS19635	COG1846	Transcriptional regulator
GII77_RS19640	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GII77_RS19645	COG0477	Major facilitator Superfamily
GII77_RS19650	COG1959	2 iron, 2 sulfur cluster binding
GII77_RS19655	COG3465	dGTPase activity
GII77_RS19660	COG1078	dGTPase activity
GII77_RS19665	COG4844	belongs to the
GII77_RS19675	COG0697	spore germination
GII77_RS19680	COG0095	Lipoate-protein ligase
GII77_RS19685	COG0583	DNA-binding transcription factor activity
GII77_RS19690	COG0280	phosphate acetyltransferase
GII77_RS19695	COG3253	May function as heme-dependent peroxidase
GII77_RS19700	COG1028	Short-chain dehydrogenase reductase Sdr
GII77_RS19705	COG0436	Aminotransferase
GII77_RS19710	COG2814	Major facilitator Superfamily
GII77_RS19715	COG0151	Belongs to the GarS family
GII77_RS19720	COG1028	Short-chain dehydrogenase reductase Sdr
GII77_RS19725	COG1917	Cupin 2, conserved barrel domain protein
GII77_RS19730	COG0077	Prephenate dehydratase
GII77_RS19735	COG2814	Major facilitator Superfamily
GII77_RS19740	COG0833	amino acid
GII77_RS19745	COG4187	Peptidase family M20/M25/M40
GII77_RS19750	COG1012	belongs to the aldehyde dehydrogenase family
GII77_RS19755	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GII77_RS19765	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
GII77_RS19770	COG1091	dTDP-4-dehydrorhamnose reductase activity
GII77_RS19775	COG1088	dTDP-glucose 4,6-dehydratase activity
GII77_RS19780	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GII77_RS19785	COG3980	spore coat polysaccharide biosynthesis protein
GII77_RS19790	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
GII77_RS19795	COG2089	acid synthase
GII77_RS19800	COG0456	acetyltransferase
GII77_RS19805	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GII77_RS19810	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GII77_RS19815	COG0463	Glycosyl transferase, family 2
GII77_RS19825	COG2363	Small membrane protein
GII77_RS19830	COG2233	PERMEase
GII77_RS19840	COG1012	belongs to the aldehyde dehydrogenase family
GII77_RS19845	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GII77_RS19850	COG1216	Glycosyl transferase, family 2
GII77_RS19865	COG1695	Transcriptional regulator
GII77_RS19870	COG0351	phosphomethylpyrimidine kinase
GII77_RS19880	COG1621	beta-fructofuranosidase activity
GII77_RS19885	COG1263	PTS System
GII77_RS19885	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII77_RS19890	COG2116	formate transmembrane transporter activity
GII77_RS19895	COG3711	transcriptional antiterminator
GII77_RS19905	COG1404	Belongs to the peptidase S8 family
GII77_RS19910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII77_RS19915	COG0778	Nitroreductase
GII77_RS19920	COG0772	Belongs to the SEDS family
GII77_RS19930	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GII77_RS19935	COG1845	cytochrome c oxidase, subunit III
GII77_RS19940	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GII77_RS19945	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GII77_RS19950	COG2261	transglycosylase associated protein
GII77_RS19955	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GII77_RS19960	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GII77_RS19965	COG2246	polysaccharide biosynthetic process
GII77_RS19970	COG1309	transcriptional regulator
GII77_RS19980	COG3162	membrane
GII77_RS19985	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII77_RS19990	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GII77_RS19995	COG2837	iron assimilation
GII77_RS20000	COG2822	iron ion transport
GII77_RS20005	COG0672	)-iron permease
GII77_RS20010	COG0352	thiamine-phosphate diphosphorylase activity
GII77_RS20015	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GII77_RS20020	COG0583	DNA-binding transcription factor activity
GII77_RS20025	COG1380	Effector of murein hydrolase LrgA
GII77_RS20030	COG1346	cytolysis
GII77_RS20035	COG2814	Major facilitator Superfamily
GII77_RS20040	COG4895	conserved protein (DUF2196)
GII77_RS20045	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GII77_RS20050	COG0346	lactoylglutathione lyase activity
GII77_RS20055	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII77_RS20065	COG1263	PTS System
GII77_RS20065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII77_RS20070	COG3711	transcriptional antiterminator
GII77_RS20075	COG1442	glycosyl transferase family 8
GII77_RS20080	COG5522	Integral membrane protein (intg_mem_TP0381)
GII77_RS20085	COG1846	Transcriptional regulator
GII77_RS20090	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GII77_RS20095	COG2234	aminopeptidase activity
GII77_RS20115	COG2357	RelA SpoT domain protein
GII77_RS20120	COG1575	Belongs to the MenA family. Type 1 subfamily
GII77_RS20135	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII77_RS20140	COG1696	Membrane protein involved in D-alanine export
GII77_RS20145	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII77_RS20150	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GII77_RS20155	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
GII77_RS20160	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII77_RS20165	COG1486	melibiose metabolic process
GII77_RS20170	COG1447	Phosphotransferase system cellobiose-specific component IIA
GII77_RS20175	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII77_RS20180	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII77_RS20185	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII77_RS20185	COG3711	transcriptional antiterminator
GII77_RS20195	COG2094	Belongs to the DNA glycosylase MPG family
GII77_RS20200	COG0753	catalase activity
GII77_RS20210	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GII77_RS20215	COG1131	(ABC) transporter
GII77_RS20235	COG1595	DNA-templated transcription, initiation
GII77_RS20240	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GII77_RS20245	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GII77_RS20250	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GII77_RS20255	COG4988	ABC transporter
GII77_RS20260	COG1294	oxidase, subunit
GII77_RS20265	COG1271	oxidase subunit
GII77_RS20270	COG3493	citrate carrier protein
GII77_RS20275	COG0501	Belongs to the peptidase M48B family
GII77_RS20285	COG0726	polysaccharide deacetylase
GII77_RS20290	COG3842	ATPase activity
GII77_RS20295	COG2508	Transcriptional regulator
GII77_RS20300	COG1012	belongs to the aldehyde dehydrogenase family
GII77_RS20305	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII77_RS20315	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GII77_RS20325	COG4585	Histidine kinase
GII77_RS20330	COG2197	response regulator
GII77_RS20335	COG2195	Cleaves the N-terminal amino acid of tripeptides
GII77_RS20345	COG4894	glucomannan catabolic process
GII77_RS20350	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GII77_RS20355	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GII77_RS20360	COG1028	Short-chain dehydrogenase reductase Sdr
GII77_RS20365	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GII77_RS20370	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GII77_RS20375	COG2610	gluconate transmembrane transporter activity
GII77_RS20380	COG0500	methyltransferase
GII77_RS20385	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GII77_RS20400	COG0753	catalase activity
GII77_RS20400	COG0693	protein deglycase activity
GII77_RS20405	COG2851	Citrate transporter
GII77_RS20410	COG2273	Hydrolase Family 16
GII77_RS20415	COG3711	transcriptional antiterminator
GII77_RS20425	COG2270	Major facilitator Superfamily
GII77_RS20430	COG0513	Belongs to the DEAD box helicase family
GII77_RS20435	COG3401	FG-GAP repeat protein
GII77_RS20435	COG2755	lipolytic protein G-D-S-L family
GII77_RS20475	COG0697	spore germination
GII77_RS20490	COG0589	response to stress
GII77_RS20495	COG2723	6-phospho-beta-galactosidase activity
GII77_RS20500	COG1263	PTS System
GII77_RS20500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII77_RS20500	COG2190	(PTS) system
GII77_RS20505	COG5444	nuclease activity
GII77_RS20515	COG5444	nuclease activity
GII77_RS20530	COG3507	Belongs to the glycosyl hydrolase 43 family
GII77_RS20555	COG2986	histidine ammonia-lyase
GII77_RS20560	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GII77_RS20565	COG1228	amidohydrolase
GII77_RS20570	COG0010	Belongs to the arginase family
GII77_RS20575	COG0833	amino acid
GII77_RS20580	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GII77_RS20585	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GII77_RS20590	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GII77_RS20595	COG2390	Transcriptional regulator
GII77_RS20605	COG3192	ethanolamine utilization protein
GII77_RS20610	COG2079	MmgE PrpD family protein
GII77_RS20615	COG1473	amidohydrolase
GII77_RS20620	COG1126	abc transporter atp-binding protein
GII77_RS20625	COG0765	amino acid transport
GII77_RS20630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII77_RS20635	COG0456	acetyltransferase
GII77_RS20640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII77_RS20650	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
GII77_RS20655	COG0561	phosphatase activity
GII77_RS20685	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII77_RS20690	COG5294	Protein conserved in bacteria
GII77_RS20695	COG0577	efflux transmembrane transporter activity
GII77_RS20700	COG1136	(ABC) transporter
GII77_RS20705	COG2205	protein histidine kinase activity
GII77_RS20710	COG0745	RESPONSE REGULATOR receiver
GII77_RS20715	COG0191	fructose-bisphosphate aldolase activity
GII77_RS20720	COG1082	Xylose isomerase domain protein TIM barrel
GII77_RS20725	COG1082	Xylose isomerase domain protein TIM barrel
GII77_RS20730	COG0673	inositol 2-dehydrogenase activity
GII77_RS20735	COG2814	Major facilitator Superfamily
GII77_RS20740	COG1082	Xylose isomerase domain protein TIM barrel
GII77_RS20745	COG3962	Belongs to the TPP enzyme family
GII77_RS20750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII77_RS20755	COG3718	enzyme involved in inositol metabolism
GII77_RS20760	COG1012	belongs to the aldehyde dehydrogenase family
GII77_RS20765	COG1349	DNA-binding transcription factor activity
GII77_RS20770	COG0667	Aldo Keto reductase
GII77_RS20785	COG2814	Major facilitator Superfamily
GII77_RS20790	COG0326	Molecular chaperone. Has ATPase activity
GII77_RS20800	COG1028	Short-chain dehydrogenase reductase Sdr
GII77_RS20805	COG1309	transcriptional regulator
GII77_RS20810	COG1012	belongs to the aldehyde dehydrogenase family
GII77_RS20815	COG1714	RDD family
GII77_RS20820	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GII77_RS20830	COG1714	RDD family
GII77_RS20835	COG2311	Membrane
GII77_RS20840	COG1917	Cupin 2, conserved barrel domain protein
GII77_RS20845	COG1309	transcriptional regulator
GII77_RS20850	COG1028	Short-chain dehydrogenase reductase Sdr
GII77_RS20855	COG1846	Transcriptional regulator
GII77_RS20860	COG1380	Effector of murein hydrolase LrgA
GII77_RS20865	COG1346	cytolysis
GII77_RS20870	COG5039	Polysaccharide pyruvyl transferase
GII77_RS20875	COG1929	Belongs to the glycerate kinase type-1 family
GII77_RS20880	COG1802	Transcriptional regulator
GII77_RS20885	COG1070	Carbohydrate kinase
GII77_RS20890	COG2610	gluconate transmembrane transporter activity
GII77_RS20895	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GII77_RS20900	COG0450	alkyl hydroperoxide reductase
GII77_RS20905	COG3634	alkyl hydroperoxide reductase activity
GII77_RS20915	COG2723	6-phospho-beta-galactosidase activity
GII77_RS20930	COG2188	Transcriptional regulator
GII77_RS20940	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
GII77_RS20975	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GII77_RS20990	COG1063	alcohol dehydrogenase
GII77_RS21010	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GII77_RS21015	COG0456	acetyltransferase
GII77_RS21020	COG0457	Tetratricopeptide repeat
GII77_RS21030	COG0010	Belongs to the arginase family
GII77_RS21035	COG0833	amino acid
GII77_RS21040	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GII77_RS21045	COG3829	transcription factor binding
GII77_RS21050	COG5002	protein histidine kinase activity
GII77_RS21055	COG0745	RESPONSE REGULATOR receiver
GII77_RS21075	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII77_RS21080	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GII77_RS21085	COG4853	Protein conserved in bacteria
GII77_RS21090	COG4863	YycH protein
GII77_RS21095	COG5002	protein histidine kinase activity
GII77_RS21100	COG0745	RESPONSE REGULATOR receiver
GII77_RS21130	COG0346	lactoylglutathione lyase activity
GII77_RS21135	COG0305	Participates in initiation and elongation during chromosome replication
GII77_RS21150	COG3093	addiction module antidote protein HigA
GII77_RS21155	COG2807	transmembrane transport
GII77_RS21160	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GII77_RS21165	COG0359	binds to the 23S rRNA
GII77_RS21170	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
GII77_RS21175	COG4241	membrane
GII77_RS21185	COG5577	PFAM Coat F domain
GII77_RS21190	COG1733	regulation of RNA biosynthetic process
GII77_RS21195	COG1227	inorganic diphosphatase activity
GII77_RS21205	COG2271	Major facilitator Superfamily
GII77_RS21210	COG0789	Transcriptional regulator
GII77_RS21210	COG4978	Transcriptional regulator
GII77_RS21220	COG4319	ketosteroid isomerase
GII77_RS21225	COG1357	PFAM Pentapeptide repeats (8 copies)
GII77_RS21230	COG2814	Major facilitator Superfamily
GII77_RS21235	COG0583	DNA-binding transcription factor activity
GII77_RS21240	COG2153	protein acetylation
GII77_RS21250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII77_RS21255	COG1846	Transcriptional regulator
GII77_RS21260	COG2153	protein acetylation
GII77_RS21265	COG2364	Membrane
GII77_RS21270	COG0456	acetyltransferase
GII77_RS21275	COG2315	Protein conserved in bacteria
GII77_RS21280	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GII77_RS21290	COG2814	Major facilitator Superfamily
GII77_RS21300	COG1331	Highly conserved protein containing a thioredoxin domain
GII77_RS21315	COG0789	Transcriptional regulator
GII77_RS21320	COG0697	spore germination
GII77_RS21325	COG1331	Highly conserved protein containing a thioredoxin domain
GII77_RS21330	COG1266	CAAX protease self-immunity
GII77_RS21335	COG0477	Major facilitator Superfamily
GII77_RS21335	COG2814	Major facilitator Superfamily
GII77_RS21340	COG0110	maltose O-acetyltransferase activity
GII77_RS21345	COG0346	lactoylglutathione lyase activity
GII77_RS21350	COG1609	Transcriptional regulator
GII77_RS21355	COG0708	Exodeoxyribonuclease III
GII77_RS21360	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GII77_RS21365	COG0629	single-stranded DNA binding
GII77_RS21370	COG0360	Binds together with S18 to 16S ribosomal RNA
GII77_RS21375	COG0012	GTP binding
GII77_RS21380	COG0243	molybdopterin cofactor binding
GII77_RS21385	COG4481	Protein conserved in bacteria
GII77_RS21390	COG3949	Membrane
GII77_RS21400	COG1475	DNA binding
GII77_RS21405	COG1192	Involved in chromosome partitioning
GII77_RS21415	COG1475	DNA binding
GII77_RS21420	COG0357	Ribosomal RNA small subunit methyltransferase G
GII77_RS21425	COG0445	tRNA wobble uridine modification
GII77_RS21430	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GII77_RS21435	COG1847	R3H domain protein
GII77_RS21440	COG0706	membrane insertase activity
GII77_RS21445	COG0594	ribonuclease P activity