locus-tag	class	description
BS11774_RS00010	COG0297	glycogen (starch) synthase activity
BS11774_RS00015	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BS11774_RS00020	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BS11774_RS00025	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BS11774_RS00150	COG3859	Proton-coupled thiamine transporter YuaJ
BS11774_RS00155	COG1247	-acetyltransferase
BS11774_RS00160	COG2268	Band 7 protein
BS11774_RS00165	COG1585	Membrane protein implicated in regulation of membrane protease activity
BS11774_RS00170	COG2318	DinB family
BS11774_RS00180	COG1454	alcohol dehydrogenase
BS11774_RS00185	COG1012	belongs to the aldehyde dehydrogenase family
BS11774_RS00190	COG1510	regulation of RNA biosynthetic process
BS11774_RS00205	COG0569	domain protein
BS11774_RS00210	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BS11774_RS00215	COG4682	membrane
BS11774_RS00220	COG1705	Flagellar rod assembly protein muramidase FlgJ
BS11774_RS00230	COG5553	Cysteine dioxygenase type I
BS11774_RS00240	COG1968	undecaprenyl-diphosphatase activity
BS11774_RS00245	COG0628	permease
BS11774_RS00250	COG0673	inositol 2-dehydrogenase activity
BS11774_RS00255	COG4806	L-rhamnose isomerase
BS11774_RS00260	COG3254	rhamnose metabolic process
BS11774_RS00265	COG1070	Carbohydrate kinase
BS11774_RS00270	COG1349	DNA-binding transcription factor activity
BS11774_RS00275	COG1028	Short-chain dehydrogenase reductase Sdr
BS11774_RS00275	COG3347	Dehydrogenase
BS11774_RS00285	COG0840	transmembrane signaling receptor activity
BS11774_RS00290	COG0840	transmembrane signaling receptor activity
BS11774_RS00295	COG0840	transmembrane signaling receptor activity
BS11774_RS00300	COG0840	transmembrane signaling receptor activity
BS11774_RS00315	COG0432	Pfam Uncharacterised protein family UPF0047
BS11774_RS00325	COG0366	Alpha amylase catalytic
BS11774_RS00330	COG1253	flavin adenine dinucleotide binding
BS11774_RS00335	COG2738	Putative neutral zinc metallopeptidase
BS11774_RS00350	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BS11774_RS00365	COG0166	Belongs to the GPI family
BS11774_RS00370	COG1979	alcohol dehydrogenase
BS11774_RS00375	COG1979	alcohol dehydrogenase
BS11774_RS00380	COG2155	Conserved Protein
BS11774_RS00385	COG1098	S1 RNA binding domain
BS11774_RS00390	COG0436	Aminotransferase
BS11774_RS00395	COG1522	sequence-specific DNA binding
BS11774_RS00400	COG2267	carboxylic ester hydrolase activity
BS11774_RS00410	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BS11774_RS00415	COG2205	protein histidine kinase activity
BS11774_RS00425	COG5018	Exonuclease
BS11774_RS00435	COG2814	Major facilitator Superfamily
BS11774_RS00440	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BS11774_RS00445	COG3011	Protein conserved in bacteria
BS11774_RS00455	COG3290	protein histidine kinase activity
BS11774_RS00460	COG4565	transcriptional regulatory protein
BS11774_RS00465	COG1744	ABC transporter substrate-binding protein PnrA-like
BS11774_RS00470	COG3845	ABC transporter
BS11774_RS00475	COG4603	Belongs to the binding-protein-dependent transport system permease family
BS11774_RS00480	COG1079	Belongs to the binding-protein-dependent transport system permease family
BS11774_RS00485	COG3493	citrate carrier protein
BS11774_RS00495	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BS11774_RS00495	COG2111	Na H antiporter
BS11774_RS00500	COG2111	Na H antiporter
BS11774_RS00505	COG1006	Multisubunit Na H antiporter MnhC subunit
BS11774_RS00510	COG0651	ATP synthesis coupled electron transport
BS11774_RS00515	COG1863	multisubunit Na H antiporter MnhE subunit
BS11774_RS00520	COG2212	antiporter activity
BS11774_RS00525	COG1320	monovalent cation:proton antiporter activity
BS11774_RS00530	COG2050	protein possibly involved in aromatic compounds catabolism
BS11774_RS00535	COG2197	response regulator
BS11774_RS00545	COG3328	transposase activity
BS11774_RS00565	COG0142	geranyltranstransferase activity
BS11774_RS00585	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BS11774_RS00590	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BS11774_RS00595	COG1335	isochorismatase
BS11774_RS00600	COG5506	Protein of unknown function (DUF1694)
BS11774_RS00615	COG0628	permease
BS11774_RS00630	COG1418	mRNA catabolic process
BS11774_RS00635	COG1028	Short-chain dehydrogenase reductase Sdr
BS11774_RS00645	COG1511	domain protein
BS11774_RS00650	COG1674	ftsk spoiiie
BS11774_RS00650	COG0433	COG0433 Predicted ATPase
BS11774_RS00655	COG4499	WXG100 protein secretion system (Wss), protein YukC
BS11774_RS00660	COG5417	Belongs to the EsaB family
BS11774_RS00665	COG4842	Belongs to the WXG100 family
BS11774_RS00670	COG2508	Transcriptional regulator
BS11774_RS00670	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BS11774_RS00675	COG0686	Belongs to the AlaDH PNT family
BS11774_RS00680	COG5634	Uncharacterized conserved protein (DUF2278)
BS11774_RS00690	COG3251	PFAM MbtH domain protein
BS11774_RS00695	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BS11774_RS00700	COG3433	isochorismatase activity
BS11774_RS00700	COG1535	isochorismatase
BS11774_RS00705	COG1021	2,3-dihydroxybenzoate-AMP ligase
BS11774_RS00710	COG1169	isochorismate synthase
BS11774_RS00715	COG1028	Short-chain dehydrogenase reductase Sdr
BS11774_RS00720	COG2819	hydrolase of the alpha beta superfamily
BS11774_RS00725	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BS11774_RS00730	COG1268	BioY protein
BS11774_RS00735	COG2056	Na+-H+ antiporter family
BS11774_RS00740	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BS11774_RS00745	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BS11774_RS00750	COG3584	3D domain protein
BS11774_RS00765	COG1252	NADH dehydrogenase
BS11774_RS00770	COG0492	ferredoxin-NADP+ reductase activity
BS11774_RS00780	COG0516	GMP reductase activity
BS11774_RS00785	COG2808	Putative FMN-binding domain
BS11774_RS00790	COG0456	acetyltransferase
BS11774_RS00795	COG0316	Belongs to the HesB IscA family
BS11774_RS00800	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BS11774_RS00805	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BS11774_RS00810	COG4844	belongs to the
BS11774_RS00815	COG1252	NADH dehydrogenase
BS11774_RS00820	COG4837	Protein of unknown function (DUF1462)
BS11774_RS00825	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BS11774_RS00830	COG1506	peptidase
BS11774_RS00830	COG4946	Tricorn protease homolog
BS11774_RS00830	COG0823	Involved in the tonB-independent uptake of proteins
BS11774_RS00835	COG0083	homoserine kinase activity
BS11774_RS00840	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BS11774_RS00845	COG0460	homoserine dehydrogenase
BS11774_RS00850	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BS11774_RS00855	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BS11774_RS00860	COG0647	UMP catabolic process
BS11774_RS00865	COG2445	Protein of unknown function DUF86
BS11774_RS00870	COG4470	Protein conserved in bacteria
BS11774_RS00880	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BS11774_RS00885	COG0739	heme binding
BS11774_RS00895	COG3377	Domain of unknown function (DUF1805)
BS11774_RS00900	COG0737	Belongs to the 5'-nucleotidase family
BS11774_RS00905	COG0730	response to heat
BS11774_RS00910	COG1801	Protein of unknown function DUF72
BS11774_RS00920	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BS11774_RS00925	COG2508	Transcriptional regulator
BS11774_RS00930	COG2233	PERMEase
BS11774_RS00935	COG2233	PERMEase
BS11774_RS00940	COG3195	allantoin biosynthetic process
BS11774_RS00940	COG3648	Uricase
BS11774_RS00945	COG2351	hydroxyisourate hydrolase activity
BS11774_RS00955	COG2080	2 iron, 2 sulfur cluster binding
BS11774_RS00960	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BS11774_RS00965	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BS11774_RS00970	COG2068	MobA-Related Protein
BS11774_RS00975	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BS11774_RS00980	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BS11774_RS00985	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BS11774_RS00995	COG2356	endonuclease I
BS11774_RS01000	COG3842	ATPase activity
BS11774_RS01005	COG2188	Transcriptional regulator
BS11774_RS01010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BS11774_RS01015	COG0395	ABC-type sugar transport system, permease component
BS11774_RS01020	COG1175	transmembrane transport
BS11774_RS01025	COG1653	transport
BS11774_RS01030	COG2222	sugar isomerase
BS11774_RS01035	COG0322	excinuclease ABC activity
BS11774_RS01040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BS11774_RS01060	COG0346	lactoylglutathione lyase activity
BS11774_RS01065	COG0640	Transcriptional regulator
BS11774_RS01080	COG5444	nuclease activity
BS11774_RS01095	COG4824	toxin secretion phage lysis holin
BS11774_RS01180	COG0305	Participates in initiation and elongation during chromosome replication
BS11774_RS01205	COG3645	SOS response
BS11774_RS01205	COG3646	Phage regulatory protein
BS11774_RS01250	COG3328	transposase activity
BS11774_RS01260	COG0719	Fe-S assembly protein
BS11774_RS01265	COG0822	iron-sulfur transferase activity
BS11774_RS01270	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BS11774_RS01275	COG0719	Fe-S assembly protein
BS11774_RS01280	COG0396	ATPase activity
BS11774_RS01295	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BS11774_RS01300	COG1464	Belongs to the NlpA lipoprotein family
BS11774_RS01305	COG2011	ABC-type metal ion transport system permease component
BS11774_RS01310	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BS11774_RS01320	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS11774_RS01325	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BS11774_RS01335	COG0509	glycine decarboxylation via glycine cleavage system
BS11774_RS01340	COG1393	Belongs to the ArsC family
BS11774_RS01345	COG1960	acyl-CoA dehydrogenase activity
BS11774_RS01350	COG0183	Belongs to the thiolase family
BS11774_RS01355	COG1024	Enoyl-CoA hydratase
BS11774_RS01355	COG1250	3-hydroxyacyl-CoA dehydrogenase
BS11774_RS01365	COG0506	proline dehydrogenase activity
BS11774_RS01375	COG5577	PFAM Coat F domain
BS11774_RS01380	COG1846	Transcriptional regulator
BS11774_RS01385	COG0477	Major facilitator Superfamily
BS11774_RS01390	COG1942	4-Oxalocrotonate Tautomerase
BS11774_RS01395	COG1028	Short-chain dehydrogenase reductase Sdr
BS11774_RS01400	COG0583	DNA-binding transcription factor activity
BS11774_RS01410	COG1120	ATPase activity
BS11774_RS01425	COG1028	Short-chain dehydrogenase reductase Sdr
BS11774_RS01430	COG0783	Belongs to the Dps family
BS11774_RS01435	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BS11774_RS01440	COG0745	RESPONSE REGULATOR receiver
BS11774_RS01445	COG2205	protein histidine kinase activity
BS11774_RS01445	COG2770	Histidine kinase
BS11774_RS01455	COG1309	transcriptional regulator
BS11774_RS01460	COG0114	fumarate hydratase activity
BS11774_RS01470	COG0697	spore germination
BS11774_RS01475	COG0814	amino acid
BS11774_RS01485	COG2197	response regulator
BS11774_RS01490	COG4585	Histidine kinase
BS11774_RS01495	COG4758	membrane
BS11774_RS01500	COG3595	metallopeptidase activity
BS11774_RS01505	COG1842	Phage shock protein A
BS11774_RS01510	COG4758	membrane
BS11774_RS01515	COG2814	Major facilitator Superfamily
BS11774_RS01520	COG2096	Adenosyltransferase
BS11774_RS01525	COG1120	ATPase activity
BS11774_RS01530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS11774_RS01535	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS11774_RS01540	COG1028	Short-chain dehydrogenase reductase Sdr
BS11774_RS01545	COG3386	PFAM SMP-30 Gluconolaconase
BS11774_RS01550	COG2205	protein histidine kinase activity
BS11774_RS01555	COG0745	RESPONSE REGULATOR receiver
BS11774_RS01565	COG1191	sigma factor activity
BS11774_RS01575	COG2140	Oxalate decarboxylase
BS11774_RS01585	COG0577	efflux transmembrane transporter activity
BS11774_RS01590	COG1136	(ABC) transporter
BS11774_RS01595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BS11774_RS01600	COG1120	ATPase activity
BS11774_RS01605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS11774_RS01610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS11774_RS01615	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS11774_RS01625	COG0531	amino acid
BS11774_RS01640	COG1988	membrane-bound metal-dependent
BS11774_RS01645	COG1368	sulfuric ester hydrolase activity
BS11774_RS01650	COG1910	domain protein
BS11774_RS01655	COG0725	ABC transporter, periplasmic molybdate-binding protein
BS11774_RS01660	COG4149	molybdate abc transporter
BS11774_RS01665	COG0656	L-ascorbic acid biosynthetic process
BS11774_RS01675	COG0025	NhaP-type Na H and K H
BS11774_RS01680	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BS11774_RS01685	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BS11774_RS01690	COG3973	AAA domain
BS11774_RS01695	COG2860	membrane
BS11774_RS01700	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BS11774_RS01705	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BS11774_RS01710	COG2217	Heavy metal translocating P-type atpase
BS11774_RS01715	COG2217	Heavy metal translocating P-type atpase
BS11774_RS01720	COG2608	mercury ion transmembrane transporter activity
BS11774_RS01725	COG1937	Protein conserved in bacteria
BS11774_RS01730	COG0673	inositol 2-dehydrogenase activity
BS11774_RS01735	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BS11774_RS01740	COG1289	transmembrane transporter activity
BS11774_RS01755	COG1309	transcriptional regulator
BS11774_RS01760	COG1028	Short-chain dehydrogenase reductase Sdr
BS11774_RS01770	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BS11774_RS01775	COG0557	exoribonuclease II activity
BS11774_RS01780	COG1647	Serine aminopeptidase, S33
BS11774_RS01785	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BS11774_RS01790	COG0596	Alpha beta hydrolase
BS11774_RS01795	COG1476	TRANSCRIPTIONal
BS11774_RS01800	COG1396	sequence-specific DNA binding
BS11774_RS01805	COG1396	sequence-specific DNA binding
BS11774_RS01810	COG1733	regulation of RNA biosynthetic process
BS11774_RS01815	COG0840	transmembrane signaling receptor activity
BS11774_RS01820	COG1174	glycine betaine transport
BS11774_RS01825	COG1732	Glycine betaine
BS11774_RS01830	COG1174	glycine betaine transport
BS11774_RS01835	COG0517	IMP dehydrogenase activity
BS11774_RS01835	COG1125	glycine betaine transport
BS11774_RS01840	COG1510	regulation of RNA biosynthetic process
BS11774_RS01845	COG1174	glycine betaine transport
BS11774_RS01850	COG1732	Glycine betaine
BS11774_RS01855	COG1174	glycine betaine transport
BS11774_RS01860	COG0517	IMP dehydrogenase activity
BS11774_RS01860	COG1125	glycine betaine transport
BS11774_RS01865	COG1510	regulation of RNA biosynthetic process
BS11774_RS01870	COG2095	MarC family integral membrane protein
BS11774_RS01880	COG3064	Membrane
BS11774_RS01885	COG4640	response to antibiotic
BS11774_RS01890	COG0456	acetyltransferase
BS11774_RS01900	COG0148	phosphopyruvate hydratase activity
BS11774_RS01905	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BS11774_RS01910	COG0149	triose-phosphate isomerase activity
BS11774_RS01915	COG0126	phosphoglycerate kinase activity
BS11774_RS01920	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BS11774_RS01925	COG2390	Transcriptional regulator
BS11774_RS01930	COG2814	Major facilitator Superfamily
BS11774_RS01935	COG1609	Transcriptional regulator
BS11774_RS01940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BS11774_RS01950	COG0583	DNA-binding transcription factor activity
BS11774_RS01955	COG0697	spore germination
BS11774_RS01960	COG1113	amino acid transport
BS11774_RS01965	COG3858	chitin binding
BS11774_RS01970	COG1556	Lactate utilization protein
BS11774_RS01975	COG1139	Iron-sulfur cluster binding protein
BS11774_RS01980	COG0247	lactate metabolic process
BS11774_RS01985	COG2197	response regulator
BS11774_RS01990	COG4585	Histidine kinase
BS11774_RS01995	COG0842	Transport permease protein
BS11774_RS02000	COG1131	(ABC) transporter
BS11774_RS02005	COG0596	Alpha beta hydrolase
BS11774_RS02010	COG2208	phosphoserine phosphatase activity
BS11774_RS02015	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BS11774_RS02020	COG1874	Beta-galactosidase
BS11774_RS02025	COG3833	ABC-type maltose transport systems, permease component
BS11774_RS02030	COG1175	transmembrane transport
BS11774_RS02035	COG2182	Extracellular solute-binding protein
BS11774_RS02040	COG1609	Transcriptional regulator
BS11774_RS02045	COG2186	Transcriptional regulator
BS11774_RS02050	COG1620	l-lactate permease
BS11774_RS02055	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BS11774_RS02065	COG5039	Polysaccharide pyruvyl transferase
BS11774_RS02070	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BS11774_RS02075	COG0110	maltose O-acetyltransferase activity
BS11774_RS02080	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BS11774_RS02085	COG2244	polysaccharide biosynthetic process
BS11774_RS02090	COG1216	Glycosyl transferase, family 2
BS11774_RS02095	COG5039	Polysaccharide pyruvyl transferase
BS11774_RS02100	COG1216	Glycosyl transferase, family 2
BS11774_RS02110	COG0438	transferase activity, transferring glycosyl groups
BS11774_RS02115	COG1215	transferase activity, transferring glycosyl groups
BS11774_RS02125	COG1086	Polysaccharide biosynthesis protein
BS11774_RS02130	COG0489	protein tyrosine kinase activity
BS11774_RS02135	COG3944	biosynthesis protein
BS11774_RS02140	COG1396	sequence-specific DNA binding
BS11774_RS02145	COG2272	Belongs to the type-B carboxylesterase lipase family
BS11774_RS02155	COG3479	Phenolic acid decarboxylase
BS11774_RS02165	COG1794	racemase activity, acting on amino acids and derivatives
BS11774_RS02170	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BS11774_RS02175	COG1621	beta-fructofuranosidase activity
BS11774_RS02180	COG1621	beta-fructofuranosidase activity
BS11774_RS02185	COG0531	amino acid
BS11774_RS02190	COG1309	transcriptional regulator
BS11774_RS02195	COG2076	Multidrug Resistance protein
BS11774_RS02200	COG2076	Multidrug Resistance protein
BS11774_RS02215	COG0740	serine-type endopeptidase activity
BS11774_RS02220	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BS11774_RS02225	COG0366	Alpha amylase catalytic
BS11774_RS02230	COG1554	hydrolase, family 65, central catalytic
BS11774_RS02235	COG5521	maltodextrose utilization protein MalA
BS11774_RS02240	COG3833	ABC-type maltose transport systems, permease component
BS11774_RS02245	COG1175	transmembrane transport
BS11774_RS02250	COG2182	Extracellular solute-binding protein
BS11774_RS02255	COG0366	Alpha amylase catalytic
BS11774_RS02260	COG1609	Transcriptional regulator
BS11774_RS02265	COG1611	Belongs to the LOG family
BS11774_RS02270	COG1694	Mazg nucleotide pyrophosphohydrolase
BS11774_RS02275	COG0659	secondary active sulfate transmembrane transporter activity
BS11774_RS02280	COG0288	reversible hydration of carbon dioxide
BS11774_RS02290	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BS11774_RS02295	COG0577	efflux transmembrane transporter activity
BS11774_RS02300	COG1136	(ABC) transporter
BS11774_RS02305	COG5002	protein histidine kinase activity
BS11774_RS02310	COG0745	RESPONSE REGULATOR receiver
BS11774_RS02320	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BS11774_RS02325	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS11774_RS02330	COG1481	regulation of sporulation
BS11774_RS02335	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BS11774_RS02340	COG1660	Displays ATPase and GTPase activities
BS11774_RS02345	COG1051	belongs to the nudix hydrolase family
BS11774_RS02350	COG0492	ferredoxin-NADP+ reductase activity
BS11774_RS02355	COG3883	PFAM NLP P60 protein
BS11774_RS02355	COG0791	NLP P60 protein
BS11774_RS02360	COG0457	Tetratricopeptide repeat
BS11774_RS02365	COG1132	(ABC) transporter
BS11774_RS02385	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BS11774_RS02385	COG0140	phosphoribosyl-ATP diphosphatase activity
BS11774_RS02390	COG0107	imidazoleglycerol-phosphate synthase activity
BS11774_RS02395	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BS11774_RS02400	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BS11774_RS02405	COG0131	Imidazoleglycerol-phosphate dehydratase
BS11774_RS02410	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BS11774_RS02415	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BS11774_RS02420	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BS11774_RS02425	COG4990	cell redox homeostasis
BS11774_RS02430	COG5297	Belongs to the glycosyl hydrolase family 6
BS11774_RS02435	COG0110	maltose O-acetyltransferase activity
BS11774_RS02440	COG0546	phosphoglycolate phosphatase activity
BS11774_RS02445	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BS11774_RS02450	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BS11774_RS02455	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BS11774_RS02460	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BS11774_RS02465	COG0363	glucosamine-6-phosphate deaminase activity
BS11774_RS02470	COG2188	Transcriptional regulator
BS11774_RS02475	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BS11774_RS02480	COG1950	PFAM Membrane protein of
BS11774_RS02485	COG1983	PspC domain protein
BS11774_RS02490	COG3595	metallopeptidase activity
BS11774_RS02505	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BS11774_RS02510	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BS11774_RS02515	COG0556	nucleotide-excision repair
BS11774_RS02520	COG4897	Protein conserved in bacteria
BS11774_RS02525	COG3848	Pyruvate phosphate dikinase
BS11774_RS02525	COG0574	Belongs to the PEP-utilizing enzyme family
BS11774_RS02530	COG1309	transcriptional regulator
BS11774_RS02535	COG2814	Major facilitator Superfamily
BS11774_RS02540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BS11774_RS02550	COG0793	Belongs to the peptidase S41A family
BS11774_RS02550	COG3409	Peptidoglycan-binding domain 1 protein
BS11774_RS02555	COG2177	Part of the ABC transporter FtsEX involved in
BS11774_RS02560	COG2884	Cell division ATP-binding protein ftsE
BS11774_RS02565	COG2010	Cytochrome c
BS11774_RS02570	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BS11774_RS02580	COG0653	protein targeting
BS11774_RS02585	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BS11774_RS02600	COG1516	flagellar protein fliS
BS11774_RS02605	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BS11774_RS02610	COG1334	flagellar protein FlaG
BS11774_RS02615	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BS11774_RS02620	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BS11774_RS02625	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BS11774_RS02635	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BS11774_RS02640	COG4786	Flagellar basal body rod
BS11774_RS02640	COG1256	bacterial-type flagellum assembly
BS11774_RS02645	COG3418	PFAM FlgN family protein
BS11774_RS02650	COG2747	anti-sigma28 factor FlgM
BS11774_RS02660	COG1040	competence protein
BS11774_RS02670	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BS11774_RS02675	COG1307	EDD domain protein, DegV family
BS11774_RS02680	COG2197	response regulator
BS11774_RS02685	COG4585	Histidine kinase
BS11774_RS02690	COG1739	Uncharacterized protein family UPF0029
BS11774_RS02695	COG1316	TRANSCRIPTIONal
BS11774_RS02700	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BS11774_RS02705	COG0438	transferase activity, transferring glycosyl groups
BS11774_RS02710	COG1215	transferase activity, transferring glycosyl groups
BS11774_RS02715	COG3206	protein involved in exopolysaccharide biosynthesis
BS11774_RS02720	COG3307	-O-antigen
BS11774_RS02725	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BS11774_RS02730	COG0438	transferase activity, transferring glycosyl groups
BS11774_RS02730	COG0297	glycogen (starch) synthase activity
BS11774_RS02735	COG2244	polysaccharide biosynthetic process
BS11774_RS02750	COG0860	N-Acetylmuramoyl-L-alanine amidase
BS11774_RS02750	COG2247	cell wall binding repeat
BS11774_RS02755	COG2385	sporulation resulting in formation of a cellular spore
BS11774_RS02755	COG2247	cell wall binding repeat
BS11774_RS02765	COG1316	TRANSCRIPTIONal
BS11774_RS02770	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BS11774_RS02790	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BS11774_RS02795	COG1134	teichoic acid transport
BS11774_RS02800	COG1682	transport, permease protein
BS11774_RS02815	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BS11774_RS02815	COG1215	transferase activity, transferring glycosyl groups
BS11774_RS02820	COG0463	Glycosyl transferase, family 2
BS11774_RS02865	COG4193	domain, Protein
BS11774_RS02870	COG1482	cell wall glycoprotein biosynthetic process
BS11774_RS02875	COG0697	spore germination
BS11774_RS02880	COG0814	amino acid
BS11774_RS02890	COG2814	Major facilitator Superfamily
BS11774_RS02895	COG1316	TRANSCRIPTIONal
BS11774_RS02900	COG0561	phosphatase activity
BS11774_RS02910	COG0791	NLP P60 protein
BS11774_RS02920	COG2843	Capsule synthesis protein
BS11774_RS02930	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BS11774_RS02935	COG1609	Transcriptional regulator
BS11774_RS02940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BS11774_RS02945	COG1869	D-ribose catabolic process
BS11774_RS02950	COG1129	ABC transporter
BS11774_RS02955	COG1172	Belongs to the binding-protein-dependent transport system permease family
BS11774_RS02960	COG1879	ABC-type sugar transport system periplasmic component
BS11774_RS02965	COG3103	Sh3 type 3 domain protein
BS11774_RS02975	COG2249	NAD(P)H dehydrogenase (quinone) activity
BS11774_RS02980	COG3527	Alpha-acetolactate decarboxylase
BS11774_RS02985	COG0028	Belongs to the TPP enzyme family
BS11774_RS02990	COG0583	DNA-binding transcription factor activity
BS11774_RS02995	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BS11774_RS03010	COG5337	Spore coat protein CotH
BS11774_RS03020	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BS11774_RS03030	COG0405	Gamma-glutamyltransferase
BS11774_RS03035	COG1522	sequence-specific DNA binding
BS11774_RS03040	COG2059	Chromate
BS11774_RS03045	COG2059	Chromate
BS11774_RS03055	COG0655	NAD(P)H dehydrogenase (quinone) activity
BS11774_RS03060	COG0583	DNA-binding transcription factor activity
BS11774_RS03075	COG5444	nuclease activity
BS11774_RS03095	COG3878	Protein conserved in bacteria
BS11774_RS03100	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BS11774_RS03105	COG4464	protein tyrosine phosphatase activity
BS11774_RS03110	COG0489	protein tyrosine kinase activity
BS11774_RS03115	COG3944	biosynthesis protein
BS11774_RS03130	COG4715	Zinc finger, swim domain protein
BS11774_RS03135	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BS11774_RS03145	COG0561	phosphatase activity
BS11774_RS03150	COG1349	DNA-binding transcription factor activity
BS11774_RS03155	COG0629	single-stranded DNA binding
BS11774_RS03170	COG3764	Sortase (surface protein transpeptidase)
BS11774_RS03175	COG2972	Histidine kinase
BS11774_RS03175	COG0745	RESPONSE REGULATOR receiver
BS11774_RS03180	COG1970	mechanosensitive ion channel activity
BS11774_RS03185	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BS11774_RS03190	COG0457	Tetratricopeptide repeat
BS11774_RS03195	COG4786	Flagellar basal body rod
BS11774_RS03200	COG4786	Flagellar basal body rod
BS11774_RS03205	COG1077	Cell shape determining protein MreB Mrl
BS11774_RS03210	COG1609	Transcriptional regulator
BS11774_RS03220	COG1846	Transcriptional regulator
BS11774_RS03225	COG2814	Major facilitator Superfamily
BS11774_RS03230	COG3420	alginic acid biosynthetic process
BS11774_RS03235	COG1953	Uracil, thiamine, allantoin
BS11774_RS03240	COG0477	Major facilitator Superfamily
BS11774_RS03245	COG1335	isochorismatase
BS11774_RS03255	COG0004	ammonium transporteR
BS11774_RS03260	COG0347	Belongs to the P(II) protein family
BS11774_RS03265	COG0671	phosphoesterase, PA-phosphatase related
BS11774_RS03275	COG0739	heme binding
BS11774_RS03280	COG1247	-acetyltransferase
BS11774_RS03300	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BS11774_RS03305	COG0789	Transcriptional regulator
BS11774_RS03315	COG2910	NAD(P)H-binding
BS11774_RS03320	COG1959	2 iron, 2 sulfur cluster binding
BS11774_RS03325	COG0804	urea catabolic process
BS11774_RS03330	COG0832	Belongs to the urease beta subunit family
BS11774_RS03335	COG0831	urea catabolic process
BS11774_RS03350	COG3237	CsbD-like
BS11774_RS03355	COG1994	Peptidase M50
BS11774_RS03360	COG0457	Tetratricopeptide repeat
BS11774_RS03365	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BS11774_RS03370	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BS11774_RS03380	COG2304	oxidoreductase activity
BS11774_RS03390	COG2304	oxidoreductase activity
BS11774_RS03395	COG2385	sporulation resulting in formation of a cellular spore
BS11774_RS03400	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BS11774_RS03410	COG4836	Membrane
BS11774_RS03420	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BS11774_RS03425	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BS11774_RS03430	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BS11774_RS03435	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BS11774_RS03440	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BS11774_RS03445	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BS11774_RS03455	COG0356	it plays a direct role in the translocation of protons across the membrane
BS11774_RS03465	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BS11774_RS03470	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BS11774_RS03475	COG4475	Protein of unknown function (DUF436)
BS11774_RS03480	COG0698	ribose 5-phosphate isomerase
BS11774_RS03485	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BS11774_RS03490	COG1971	Probably functions as a manganese efflux pump
BS11774_RS03495	COG0009	L-threonylcarbamoyladenylate synthase
BS11774_RS03500	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BS11774_RS03520	COG2890	protein-(glutamine-N5) methyltransferase activity
BS11774_RS03525	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BS11774_RS03530	COG0346	lactoylglutathione lyase activity
BS11774_RS03535	COG0789	Transcriptional regulator
BS11774_RS03540	COG0679	Auxin Efflux Carrier
BS11774_RS03545	COG0281	malic enzyme
BS11774_RS03550	COG1435	thymidine kinase activity
BS11774_RS03560	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BS11774_RS03570	COG1494	fructose-1,6-bisphosphatase
BS11774_RS03575	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BS11774_RS03580	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BS11774_RS03585	COG0191	fructose-bisphosphate aldolase activity
BS11774_RS03590	COG2204	response regulator
BS11774_RS03595	COG4821	SIS domain
BS11774_RS03605	COG0504	CTP synthase activity
BS11774_RS03610	COG3343	RNA polymerase activity
BS11774_RS03615	COG1960	acyl-CoA dehydrogenase activity
BS11774_RS03620	COG2181	nitrate reductase activity
BS11774_RS03620	COG0247	lactate metabolic process
BS11774_RS03625	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BS11774_RS03630	COG4294	response to UV
BS11774_RS03640	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BS11774_RS03645	COG1132	(ABC) transporter
BS11774_RS03660	COG2181	nitrate reductase activity
BS11774_RS03665	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BS11774_RS03670	COG1140	nitrate reductase beta subunit
BS11774_RS03675	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BS11774_RS03680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BS11774_RS03690	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BS11774_RS03695	COG2223	nitrite transmembrane transporter activity
BS11774_RS03700	COG0018	arginyl-trna synthetase
BS11774_RS03705	COG4506	Protein conserved in bacteria
BS11774_RS03720	COG0535	radical SAM domain protein
BS11774_RS03730	COG1131	(ABC) transporter
BS11774_RS03735	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BS11774_RS03740	COG0612	Peptidase, M16
BS11774_RS03745	COG0612	Peptidase, M16
BS11774_RS03755	COG3391	amine dehydrogenase activity
BS11774_RS03760	COG3391	amine dehydrogenase activity
BS11774_RS03770	COG0457	Tetratricopeptide repeat
BS11774_RS03785	COG0010	Belongs to the arginase family
BS11774_RS03790	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BS11774_RS03795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BS11774_RS03810	COG1994	Peptidase M50
BS11774_RS03815	COG1942	4-Oxalocrotonate Tautomerase
BS11774_RS03820	COG1846	Transcriptional regulator
BS11774_RS03825	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BS11774_RS03840	COG0477	Major facilitator Superfamily
BS11774_RS03845	COG1959	2 iron, 2 sulfur cluster binding
BS11774_RS03850	COG3465	dGTPase activity
BS11774_RS03855	COG1078	dGTPase activity
BS11774_RS03860	COG4844	belongs to the
BS11774_RS03870	COG0697	spore germination
BS11774_RS03875	COG0095	Lipoate-protein ligase
BS11774_RS03880	COG0583	DNA-binding transcription factor activity
BS11774_RS03885	COG0280	phosphate acetyltransferase
BS11774_RS03890	COG3253	May function as heme-dependent peroxidase
BS11774_RS03900	COG2814	Major facilitator Superfamily
BS11774_RS03910	COG1028	Short-chain dehydrogenase reductase Sdr
BS11774_RS03915	COG1917	Cupin 2, conserved barrel domain protein
BS11774_RS03920	COG0077	Prephenate dehydratase
BS11774_RS03925	COG2814	Major facilitator Superfamily
BS11774_RS03930	COG0833	amino acid
BS11774_RS03935	COG4187	Peptidase family M20/M25/M40
BS11774_RS03940	COG1012	belongs to the aldehyde dehydrogenase family
BS11774_RS03945	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BS11774_RS03955	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
BS11774_RS03960	COG1091	dTDP-4-dehydrorhamnose reductase activity
BS11774_RS03965	COG1088	dTDP-glucose 4,6-dehydratase activity
BS11774_RS03970	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BS11774_RS03975	COG3980	spore coat polysaccharide biosynthesis protein
BS11774_RS03980	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
BS11774_RS03985	COG2089	acid synthase
BS11774_RS03990	COG0456	acetyltransferase
BS11774_RS03995	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BS11774_RS04000	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BS11774_RS04005	COG0463	Glycosyl transferase, family 2
BS11774_RS04020	COG2363	Small membrane protein
BS11774_RS04025	COG2233	PERMEase
BS11774_RS04035	COG1012	belongs to the aldehyde dehydrogenase family
BS11774_RS04040	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BS11774_RS04045	COG1216	Glycosyl transferase, family 2
BS11774_RS04060	COG1695	Transcriptional regulator
BS11774_RS04065	COG0351	phosphomethylpyrimidine kinase
BS11774_RS04075	COG1621	beta-fructofuranosidase activity
BS11774_RS04085	COG2116	formate transmembrane transporter activity
BS11774_RS04090	COG3711	transcriptional antiterminator
BS11774_RS04100	COG1404	Belongs to the peptidase S8 family
BS11774_RS04105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BS11774_RS04110	COG0778	Nitroreductase
BS11774_RS04115	COG0772	Belongs to the SEDS family
BS11774_RS04125	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BS11774_RS04130	COG1845	cytochrome c oxidase, subunit III
BS11774_RS04135	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BS11774_RS04140	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BS11774_RS04145	COG2261	transglycosylase associated protein
BS11774_RS04150	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BS11774_RS04155	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BS11774_RS04160	COG2246	polysaccharide biosynthetic process
BS11774_RS04165	COG1309	transcriptional regulator
BS11774_RS04175	COG3162	membrane
BS11774_RS04180	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BS11774_RS04185	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BS11774_RS04190	COG2837	iron assimilation
BS11774_RS04195	COG2822	iron ion transport
BS11774_RS04200	COG0672	)-iron permease
BS11774_RS04205	COG0352	thiamine-phosphate diphosphorylase activity
BS11774_RS04210	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BS11774_RS04215	COG0583	DNA-binding transcription factor activity
BS11774_RS04220	COG1380	Effector of murein hydrolase LrgA
BS11774_RS04225	COG1346	cytolysis
BS11774_RS04230	COG2814	Major facilitator Superfamily
BS11774_RS04235	COG4895	conserved protein (DUF2196)
BS11774_RS04240	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BS11774_RS04245	COG0346	lactoylglutathione lyase activity
BS11774_RS04255	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BS11774_RS04260	COG1404	Belongs to the peptidase S8 family
BS11774_RS04265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS11774_RS04265	COG1263	PTS System
BS11774_RS04270	COG3711	transcriptional antiterminator
BS11774_RS04275	COG1442	glycosyl transferase family 8
BS11774_RS04285	COG1846	Transcriptional regulator
BS11774_RS04290	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BS11774_RS04300	COG2357	RelA SpoT domain protein
BS11774_RS04310	COG1575	Belongs to the MenA family. Type 1 subfamily
BS11774_RS04330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BS11774_RS04335	COG1696	Membrane protein involved in D-alanine export
BS11774_RS04340	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BS11774_RS04345	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BS11774_RS04350	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
BS11774_RS04355	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BS11774_RS04360	COG1486	melibiose metabolic process
BS11774_RS04365	COG1447	Phosphotransferase system cellobiose-specific component IIA
BS11774_RS04370	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BS11774_RS04375	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BS11774_RS04380	COG3711	transcriptional antiterminator
BS11774_RS04380	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS11774_RS04390	COG2094	Belongs to the DNA glycosylase MPG family
BS11774_RS04395	COG0753	catalase activity
BS11774_RS04405	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BS11774_RS04410	COG1131	(ABC) transporter
BS11774_RS04430	COG1595	DNA-templated transcription, initiation
BS11774_RS04435	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BS11774_RS04440	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BS11774_RS04445	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BS11774_RS04450	COG4988	ABC transporter
BS11774_RS04455	COG1294	oxidase, subunit
BS11774_RS04460	COG1271	oxidase subunit
BS11774_RS04465	COG3493	citrate carrier protein
BS11774_RS04470	COG0501	Belongs to the peptidase M48B family
BS11774_RS04480	COG0726	polysaccharide deacetylase
BS11774_RS04485	COG3842	ATPase activity
BS11774_RS04490	COG2508	Transcriptional regulator
BS11774_RS04495	COG1012	belongs to the aldehyde dehydrogenase family
BS11774_RS04500	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BS11774_RS04505	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BS11774_RS04515	COG4585	Histidine kinase
BS11774_RS04520	COG2197	response regulator
BS11774_RS04525	COG2195	Cleaves the N-terminal amino acid of tripeptides
BS11774_RS04535	COG4894	glucomannan catabolic process
BS11774_RS04545	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BS11774_RS04550	COG1028	Short-chain dehydrogenase reductase Sdr
BS11774_RS04555	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BS11774_RS04560	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BS11774_RS04565	COG2610	gluconate transmembrane transporter activity
BS11774_RS04570	COG0500	methyltransferase
BS11774_RS04575	COG2323	membrane
BS11774_RS04580	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BS11774_RS04590	COG2323	membrane
BS11774_RS04605	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BS11774_RS04630	COG3546	catalase activity
BS11774_RS04665	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BS11774_RS04685	COG2851	Citrate transporter
BS11774_RS04690	COG2273	Hydrolase Family 16
BS11774_RS04695	COG3711	transcriptional antiterminator
BS11774_RS04710	COG2270	Major facilitator Superfamily
BS11774_RS04715	COG0513	Belongs to the DEAD box helicase family
BS11774_RS04720	COG3401	FG-GAP repeat protein
BS11774_RS04720	COG2755	lipolytic protein G-D-S-L family
BS11774_RS04775	COG3209	COG3209 Rhs family protein
BS11774_RS04780	COG0697	spore germination
BS11774_RS04785	COG0589	response to stress
BS11774_RS04790	COG2723	6-phospho-beta-galactosidase activity
BS11774_RS04795	COG2190	(PTS) system
BS11774_RS04795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS11774_RS04795	COG1263	PTS System
BS11774_RS04805	COG5444	nuclease activity
BS11774_RS04840	COG3507	Belongs to the glycosyl hydrolase 43 family
BS11774_RS04850	COG2986	histidine ammonia-lyase
BS11774_RS04855	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BS11774_RS04860	COG1228	amidohydrolase
BS11774_RS04865	COG0010	Belongs to the arginase family
BS11774_RS04870	COG0833	amino acid
BS11774_RS04875	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BS11774_RS04880	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BS11774_RS04885	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BS11774_RS04890	COG2390	Transcriptional regulator
BS11774_RS04900	COG3192	ethanolamine utilization protein
BS11774_RS04905	COG2079	MmgE PrpD family protein
BS11774_RS04910	COG1473	amidohydrolase
BS11774_RS04915	COG1126	abc transporter atp-binding protein
BS11774_RS04920	COG0765	amino acid transport
BS11774_RS04925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BS11774_RS04930	COG0456	acetyltransferase
BS11774_RS04935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BS11774_RS04945	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BS11774_RS04950	COG0561	phosphatase activity
BS11774_RS04980	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS11774_RS04985	COG5294	Protein conserved in bacteria
BS11774_RS04990	COG0577	efflux transmembrane transporter activity
BS11774_RS04995	COG1136	(ABC) transporter
BS11774_RS05000	COG2205	protein histidine kinase activity
BS11774_RS05005	COG0745	RESPONSE REGULATOR receiver
BS11774_RS05010	COG0191	fructose-bisphosphate aldolase activity
BS11774_RS05015	COG1082	Xylose isomerase domain protein TIM barrel
BS11774_RS05020	COG1082	Xylose isomerase domain protein TIM barrel
BS11774_RS05025	COG0673	inositol 2-dehydrogenase activity
BS11774_RS05030	COG2814	Major facilitator Superfamily
BS11774_RS05035	COG1082	Xylose isomerase domain protein TIM barrel
BS11774_RS05040	COG3962	Belongs to the TPP enzyme family
BS11774_RS05045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BS11774_RS05055	COG1012	belongs to the aldehyde dehydrogenase family
BS11774_RS05060	COG1349	DNA-binding transcription factor activity
BS11774_RS05065	COG0667	Aldo Keto reductase
BS11774_RS05080	COG2814	Major facilitator Superfamily
BS11774_RS05085	COG0326	Molecular chaperone. Has ATPase activity
BS11774_RS05095	COG1028	Short-chain dehydrogenase reductase Sdr
BS11774_RS05100	COG1309	transcriptional regulator
BS11774_RS05105	COG1012	belongs to the aldehyde dehydrogenase family
BS11774_RS05115	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BS11774_RS05125	COG1714	RDD family
BS11774_RS05130	COG2311	Membrane
BS11774_RS05135	COG1917	Cupin 2, conserved barrel domain protein
BS11774_RS05140	COG1309	transcriptional regulator
BS11774_RS05145	COG1028	Short-chain dehydrogenase reductase Sdr
BS11774_RS05150	COG1846	Transcriptional regulator
BS11774_RS05155	COG1380	Effector of murein hydrolase LrgA
BS11774_RS05160	COG1346	cytolysis
BS11774_RS05165	COG5039	Polysaccharide pyruvyl transferase
BS11774_RS05170	COG1929	Belongs to the glycerate kinase type-1 family
BS11774_RS05175	COG1802	Transcriptional regulator
BS11774_RS05180	COG1070	Carbohydrate kinase
BS11774_RS05185	COG2610	gluconate transmembrane transporter activity
BS11774_RS05190	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BS11774_RS05195	COG0450	alkyl hydroperoxide reductase
BS11774_RS05200	COG3634	alkyl hydroperoxide reductase activity
BS11774_RS05210	COG2723	6-phospho-beta-galactosidase activity
BS11774_RS05215	COG2190	(PTS) system
BS11774_RS05220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS11774_RS05220	COG2190	(PTS) system
BS11774_RS05220	COG1263	PTS System
BS11774_RS05225	COG2188	Transcriptional regulator
BS11774_RS05240	COG1131	(ABC) transporter
BS11774_RS05245	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
BS11774_RS05265	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BS11774_RS05280	COG1063	alcohol dehydrogenase
BS11774_RS05300	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
BS11774_RS05310	COG0457	Tetratricopeptide repeat
BS11774_RS05320	COG0010	Belongs to the arginase family
BS11774_RS05325	COG0833	amino acid
BS11774_RS05330	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BS11774_RS05335	COG3829	transcription factor binding
BS11774_RS05340	COG5002	protein histidine kinase activity
BS11774_RS05345	COG0745	RESPONSE REGULATOR receiver
BS11774_RS05365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BS11774_RS05370	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BS11774_RS05375	COG4853	Protein conserved in bacteria
BS11774_RS05380	COG4863	YycH protein
BS11774_RS05385	COG5002	protein histidine kinase activity
BS11774_RS05390	COG0745	RESPONSE REGULATOR receiver
BS11774_RS05420	COG0346	lactoylglutathione lyase activity
BS11774_RS05425	COG0305	Participates in initiation and elongation during chromosome replication
BS11774_RS05440	COG3093	addiction module antidote protein HigA
BS11774_RS05450	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BS11774_RS05455	COG0359	binds to the 23S rRNA
BS11774_RS05460	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BS11774_RS05465	COG4241	membrane
BS11774_RS05475	COG5577	PFAM Coat F domain
BS11774_RS05480	COG1733	regulation of RNA biosynthetic process
BS11774_RS05485	COG1227	inorganic diphosphatase activity
BS11774_RS05500	COG2271	Major facilitator Superfamily
BS11774_RS05505	COG4978	Transcriptional regulator
BS11774_RS05505	COG0789	Transcriptional regulator
BS11774_RS05515	COG4319	ketosteroid isomerase
BS11774_RS05520	COG1357	PFAM Pentapeptide repeats (8 copies)
BS11774_RS05525	COG2814	Major facilitator Superfamily
BS11774_RS05530	COG0583	DNA-binding transcription factor activity
BS11774_RS05535	COG2153	protein acetylation
BS11774_RS05550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BS11774_RS05555	COG1846	Transcriptional regulator
BS11774_RS05560	COG2153	protein acetylation
BS11774_RS05565	COG2364	Membrane
BS11774_RS05570	COG0456	acetyltransferase
BS11774_RS05575	COG2315	Protein conserved in bacteria
BS11774_RS05580	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BS11774_RS05590	COG2814	Major facilitator Superfamily
BS11774_RS05600	COG1331	Highly conserved protein containing a thioredoxin domain
BS11774_RS05605	COG1266	CAAX protease self-immunity
BS11774_RS05610	COG0477	Major facilitator Superfamily
BS11774_RS05610	COG2814	Major facilitator Superfamily
BS11774_RS05615	COG0110	maltose O-acetyltransferase activity
BS11774_RS05620	COG0346	lactoylglutathione lyase activity
BS11774_RS05625	COG1609	Transcriptional regulator
BS11774_RS05630	COG0708	Exodeoxyribonuclease III
BS11774_RS05635	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BS11774_RS05640	COG0629	single-stranded DNA binding
BS11774_RS05645	COG0360	Binds together with S18 to 16S ribosomal RNA
BS11774_RS05650	COG0012	GTP binding
BS11774_RS05655	COG0243	molybdopterin cofactor binding
BS11774_RS05660	COG4481	Protein conserved in bacteria
BS11774_RS05665	COG3949	Membrane
BS11774_RS05675	COG1475	DNA binding
BS11774_RS05680	COG1192	Involved in chromosome partitioning
BS11774_RS05690	COG1475	DNA binding
BS11774_RS05695	COG0357	Ribosomal RNA small subunit methyltransferase G
BS11774_RS05700	COG0445	tRNA wobble uridine modification
BS11774_RS05705	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BS11774_RS05710	COG1847	R3H domain protein
BS11774_RS05715	COG0706	membrane insertase activity
BS11774_RS05720	COG0594	ribonuclease P activity
BS11774_RS05730	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BS11774_RS05735	COG0592	DNA-directed DNA polymerase activity
BS11774_RS05740	COG2501	S4 domain
BS11774_RS05745	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BS11774_RS05755	COG0187	DNA topoisomerase II activity
BS11774_RS05760	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BS11774_RS05795	COG0516	GMP reductase activity
BS11774_RS05795	COG0517	IMP dehydrogenase activity
BS11774_RS05800	COG1686	Belongs to the peptidase S11 family
BS11774_RS05805	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BS11774_RS05810	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BS11774_RS05815	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BS11774_RS05825	COG1428	Deoxynucleoside kinase
BS11774_RS05830	COG1428	Deoxynucleoside kinase
BS11774_RS05835	COG1388	LysM domain
BS11774_RS05835	COG3858	chitin binding
BS11774_RS05840	COG1335	isochorismatase
BS11774_RS05845	COG0590	tRNA wobble adenosine to inosine editing
BS11774_RS05855	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BS11774_RS05860	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BS11774_RS05865	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BS11774_RS05910	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
BS11774_RS05915	COG3853	Toxic anion resistance protein (TelA)
BS11774_RS05920	COG1982	Orn Lys Arg decarboxylase major
BS11774_RS05925	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BS11774_RS05930	COG3870	Protein conserved in bacteria
BS11774_RS05935	COG1728	Protein conserved in bacteria
BS11774_RS05940	COG0470	DNA polymerase III
BS11774_RS05945	COG1774	PSP1 C-terminal conserved region
BS11774_RS05950	COG4467	Involved in initiation control of chromosome replication
BS11774_RS05955	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BS11774_RS05960	COG2827	Endonuclease containing a URI domain
BS11774_RS05965	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BS11774_RS05970	COG2002	toxin-antitoxin pair type II binding
BS11774_RS05975	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BS11774_RS05975	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BS11774_RS05980	COG0084	hydrolase, TatD family'
BS11774_RS05985	COG3584	3D domain protein
BS11774_RS05985	COG3583	domain protein
BS11774_RS05990	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BS11774_RS05995	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BS11774_RS06005	COG4466	Protein conserved in bacteria
BS11774_RS06015	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BS11774_RS06020	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BS11774_RS06025	COG0251	oxidation-reduction process
BS11774_RS06030	COG2088	sporulation resulting in formation of a cellular spore
BS11774_RS06035	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BS11774_RS06040	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BS11774_RS06045	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BS11774_RS06050	COG0193	aminoacyl-tRNA hydrolase activity
BS11774_RS06060	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BS11774_RS06065	COG2002	toxin-antitoxin pair type II binding
BS11774_RS06070	COG2244	polysaccharide biosynthetic process
BS11774_RS06075	COG3956	TIGRFAM MazG family protein
BS11774_RS06080	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BS11774_RS06095	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BS11774_RS06100	COG1098	S1 RNA binding domain
BS11774_RS06115	COG2208	phosphoserine phosphatase activity
BS11774_RS06120	COG2304	oxidoreductase activity
BS11774_RS06125	COG0515	serine threonine protein kinase
BS11774_RS06130	COG0037	tRNA processing
BS11774_RS06135	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BS11774_RS06140	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BS11774_RS06150	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BS11774_RS06155	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BS11774_RS06160	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BS11774_RS06165	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BS11774_RS06170	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BS11774_RS06175	COG0512	Glutamine amidotransferase of anthranilate synthase
BS11774_RS06180	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BS11774_RS06185	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BS11774_RS06190	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BS11774_RS06195	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BS11774_RS06200	COG1396	sequence-specific DNA binding
BS11774_RS06205	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BS11774_RS06210	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BS11774_RS06230	COG4463	regulation of RNA biosynthetic process
BS11774_RS06235	COG3880	PFAM UvrB UvrC protein
BS11774_RS06240	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BS11774_RS06245	COG0542	response to heat
BS11774_RS06250	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BS11774_RS06255	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BS11774_RS06260	COG4956	integral membrane protein (PIN domain superfamily)
BS11774_RS06265	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BS11774_RS06270	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BS11774_RS06275	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BS11774_RS06285	COG1045	serine acetyltransferase
BS11774_RS06290	COG0215	cysteine-tRNA ligase activity
BS11774_RS06295	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BS11774_RS06300	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BS11774_RS06305	COG3688	RNA-binding protein containing a PIN domain
BS11774_RS06310	COG1595	DNA-templated transcription, initiation
BS11774_RS06320	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BS11774_RS06325	COG0250	Participates in transcription elongation, termination and antitermination
BS11774_RS06335	COG0081	regulation of translation
BS11774_RS06340	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BS11774_RS06350	COG2813	Specifically methylates the guanine in position
BS11774_RS06355	COG0085	RNA polymerase activity
BS11774_RS06360	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BS11774_RS06365	COG1358	cellular component organization or biogenesis
BS11774_RS06370	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BS11774_RS06375	COG0049	tRNA binding
BS11774_RS06380	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BS11774_RS06385	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BS11774_RS06390	COG0596	Alpha beta hydrolase
BS11774_RS06400	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BS11774_RS06405	COG0088	Forms part of the polypeptide exit tunnel
BS11774_RS06415	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BS11774_RS06430	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BS11774_RS06435	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BS11774_RS06445	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BS11774_RS06450	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BS11774_RS06460	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BS11774_RS06470	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BS11774_RS06475	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BS11774_RS06480	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BS11774_RS06485	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BS11774_RS06495	COG0200	Binds to the 23S rRNA
BS11774_RS06500	COG0201	protein transport
BS11774_RS06505	COG0563	adenylate kinase activity
BS11774_RS06510	COG0024	Methionine aminopeptidase
BS11774_RS06515	COG2163	COG2163 Ribosomal protein L14E L6E L27E
BS11774_RS06525	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BS11774_RS06530	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BS11774_RS06535	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BS11774_RS06540	COG0202	RNA polymerase activity
BS11774_RS06545	COG0203	ribosomal protein L17
BS11774_RS06550	COG1122	ATPase activity
BS11774_RS06555	COG1122	ATPase activity
BS11774_RS06560	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BS11774_RS06565	COG0101	tRNA pseudouridine synthase activity
BS11774_RS06570	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BS11774_RS06575	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BS11774_RS06580	COG2226	methyltransferase
BS11774_RS06590	COG0860	N-Acetylmuramoyl-L-alanine amidase
BS11774_RS06595	COG0489	protein tyrosine kinase activity
BS11774_RS06605	COG2194	sulfuric ester hydrolase activity
BS11774_RS06610	COG0726	polysaccharide deacetylase
BS11774_RS06645	COG2856	Zn peptidase
BS11774_RS06655	COG1395	domain, Protein
BS11774_RS06715	COG0305	Participates in initiation and elongation during chromosome replication
BS11774_RS06725	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
BS11774_RS06820	COG5444	nuclease activity
BS11774_RS06825	COG0457	Tetratricopeptide repeat
BS11774_RS06840	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BS11774_RS06910	COG0385	Bile acid
BS11774_RS06915	COG2819	hydrolase of the alpha beta superfamily
BS11774_RS06920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS11774_RS06925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS11774_RS06930	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS11774_RS06935	COG2207	Transcriptional regulator
BS11774_RS06935	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS11774_RS06940	COG3876	Protein conserved in bacteria
BS11774_RS06945	COG1472	Belongs to the glycosyl hydrolase 3 family
BS11774_RS06950	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BS11774_RS06955	COG1263	PTS System
BS11774_RS06955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS11774_RS06960	COG1737	Transcriptional regulator
BS11774_RS06965	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BS11774_RS06970	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS11774_RS06975	COG1683	Conserved Protein
BS11774_RS07005	COG1595	DNA-templated transcription, initiation
BS11774_RS07010	COG5662	AntiSigma factor
BS11774_RS07015	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BS11774_RS07020	COG4856	YbbR-like protein
BS11774_RS07025	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BS11774_RS07030	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BS11774_RS07040	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BS11774_RS07045	COG2169	Transcriptional regulator
BS11774_RS07050	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BS11774_RS07055	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BS11774_RS07060	COG3002	Belongs to the UPF0753 family
BS11774_RS07065	COG0288	reversible hydration of carbon dioxide
BS11774_RS07075	COG5609	conserved protein (DUF2294)
BS11774_RS07080	COG0640	Transcriptional regulator
BS11774_RS07085	COG2814	Major facilitator Superfamily
BS11774_RS07100	COG0515	serine threonine protein kinase
BS11774_RS07115	COG1113	amino acid transport
BS11774_RS07130	COG2602	Beta-lactamase
BS11774_RS07135	COG2124	cytochrome p450
BS11774_RS07145	COG0531	amino acid
BS11774_RS07155	COG0584	glycerophosphoryl diester phosphodiesterase
BS11774_RS07160	COG2271	Major facilitator Superfamily
BS11774_RS07175	COG0456	acetyltransferase
BS11774_RS07175	COG1846	Transcriptional regulator
BS11774_RS07180	COG2271	Major facilitator Superfamily
BS11774_RS07190	COG3409	Peptidoglycan-binding domain 1 protein
BS11774_RS07195	COG0697	spore germination
BS11774_RS07200	COG1917	Cupin 2, conserved barrel domain protein
BS11774_RS07200	COG2207	Transcriptional regulator
BS11774_RS07205	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BS11774_RS07210	COG3591	Belongs to the peptidase S1B family
BS11774_RS07220	COG0596	Alpha beta hydrolase
BS11774_RS07225	COG1183	phosphatidylcholine synthase activity
BS11774_RS07230	COG0586	Pfam SNARE associated Golgi protein
BS11774_RS07235	COG0688	phosphatidylethanolamine metabolic process
BS11774_RS07245	COG1054	Belongs to the UPF0176 family
BS11774_RS07250	COG1301	dicarboxylic acid transport
BS11774_RS07255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS11774_RS07255	COG1263	PTS System
BS11774_RS07255	COG2190	(PTS) system
BS11774_RS07260	COG0363	glucosamine-6-phosphate deaminase activity
BS11774_RS07265	COG2188	Transcriptional regulator
BS11774_RS07275	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BS11774_RS07280	COG0833	amino acid
BS11774_RS07285	COG2040	homocysteine
BS11774_RS07295	COG1115	amino acid carrier protein
BS11774_RS07300	COG2066	Belongs to the glutaminase family
BS11774_RS07305	COG4191	Histidine kinase
BS11774_RS07310	COG0784	Response regulator, receiver
BS11774_RS07320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BS11774_RS07325	COG1012	belongs to the aldehyde dehydrogenase family
BS11774_RS07330	COG2271	Major facilitator Superfamily
BS11774_RS07335	COG4948	Mandelate Racemase Muconate Lactonizing
BS11774_RS07340	COG2186	Transcriptional regulator
BS11774_RS07345	COG2721	sulfolactate sulfo-lyase activity
BS11774_RS07350	COG3173	Aminoglycoside phosphotransferase
BS11774_RS07360	COG0697	spore germination
BS11774_RS07365	COG0745	RESPONSE REGULATOR receiver
BS11774_RS07370	COG2205	protein histidine kinase activity
BS11774_RS07375	COG1131	(ABC) transporter
BS11774_RS07395	COG3773	Cell wall hydrolase
BS11774_RS07405	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BS11774_RS07405	COG0072	phenylalanine-tRNA ligase activity
BS11774_RS07435	COG0531	amino acid
BS11774_RS07450	COG0137	argininosuccinate synthase activity
BS11774_RS07460	COG1279	arginine transmembrane transporter activity
BS11774_RS07480	COG3540	Alkaline phosphatase
BS11774_RS07485	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BS11774_RS07490	COG0805	protein transport
BS11774_RS07495	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BS11774_RS07500	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BS11774_RS07505	COG0477	Major facilitator Superfamily
BS11774_RS07510	COG1309	transcriptional regulator
BS11774_RS07515	COG0252	asparaginase activity
BS11774_RS07520	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BS11774_RS07525	COG1714	RDD family
BS11774_RS07530	COG1405	negative regulation of cell septum assembly
BS11774_RS07530	COG3012	SEC-C Motif Domain Protein
BS11774_RS07535	COG3290	protein histidine kinase activity
BS11774_RS07540	COG3279	Response regulator of the LytR AlgR family
BS11774_RS07545	COG4555	ABC transporter
BS11774_RS07550	COG1668	transmembrane transport
BS11774_RS07555	COG0667	Aldo Keto reductase
BS11774_RS07570	COG1595	DNA-templated transcription, initiation
BS11774_RS07575	COG1595	DNA-templated transcription, initiation
BS11774_RS07580	COG1876	peptidase activity
BS11774_RS07585	COG0457	Tetratricopeptide repeat
BS11774_RS07590	COG1028	Short-chain dehydrogenase reductase Sdr
BS11774_RS07595	COG0366	Alpha amylase catalytic
BS11774_RS07600	COG0803	Belongs to the bacterial solute-binding protein 9 family
BS11774_RS07605	COG1121	(ABC) transporter
BS11774_RS07610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BS11774_RS07615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BS11774_RS07620	COG2310	stress, protein
BS11774_RS07625	COG2310	stress, protein
BS11774_RS07630	COG2310	stress, protein
BS11774_RS07635	COG0861	Integral membrane protein TerC family
BS11774_RS07645	COG3853	Toxic anion resistance protein (TelA)
BS11774_RS07650	COG0477	Major facilitator Superfamily
BS11774_RS07660	COG2814	Major facilitator Superfamily
BS11774_RS07665	COG0640	Transcriptional regulator
BS11774_RS07670	COG4175	Glycine betaine
BS11774_RS07670	COG0517	IMP dehydrogenase activity
BS11774_RS07675	COG4176	ABC-type proline glycine betaine transport system permease component
BS11774_RS07680	COG2113	Glycine betaine
BS11774_RS07685	COG1473	amidohydrolase
BS11774_RS07690	COG1288	antiporter activity
BS11774_RS07700	COG0366	Alpha amylase catalytic
BS11774_RS07705	COG0039	L-malate dehydrogenase activity
BS11774_RS07710	COG1620	l-lactate permease
BS11774_RS07715	COG2814	Major facilitator Superfamily
BS11774_RS07720	COG1846	Transcriptional regulator
BS11774_RS07725	COG1280	lysine exporter protein (LysE YggA)
BS11774_RS07730	COG3403	YqcI/YcgG family
BS11774_RS07735	COG1113	amino acid transport
BS11774_RS07740	COG3665	Urea carboxylase-associated protein
BS11774_RS07745	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BS11774_RS07750	COG1660	Displays ATPase and GTPase activities
BS11774_RS07755	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BS11774_RS07765	COG2226	methyltransferase
BS11774_RS07770	COG0583	DNA-binding transcription factor activity
BS11774_RS07775	COG3458	cephalosporin-C deacetylase activity
BS11774_RS07780	COG3541	Predicted nucleotidyltransferase
BS11774_RS07785	COG0506	proline dehydrogenase activity
BS11774_RS07790	COG1012	belongs to the aldehyde dehydrogenase family
BS11774_RS07795	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BS11774_RS07800	COG2508	Transcriptional regulator
BS11774_RS07805	COG3689	TIGRFAM TIGR03943 family protein
BS11774_RS07810	COG0701	Predicted permease
BS11774_RS07820	COG0492	ferredoxin-NADP+ reductase activity
BS11774_RS07825	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BS11774_RS07825	COG1587	Uroporphyrinogen-III synthase
BS11774_RS07830	COG2146	nitrite reductase [NAD(P)H] activity
BS11774_RS07835	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BS11774_RS07840	COG0243	molybdopterin cofactor binding
BS11774_RS07845	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BS11774_RS07850	COG2223	nitrite transmembrane transporter activity
BS11774_RS07855	COG1469	GTP cyclohydrolase I activity
BS11774_RS07860	COG1376	ErfK ybiS ycfS ynhG family protein
BS11774_RS07870	COG0523	cobalamin synthesis protein
BS11774_RS07875	COG0765	amino acid transport
BS11774_RS07880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BS11774_RS07890	COG1714	RDD family
BS11774_RS07900	COG2723	6-phospho-beta-galactosidase activity
BS11774_RS07910	COG3209	COG3209 Rhs family protein
BS11774_RS07915	COG0840	transmembrane signaling receptor activity
BS11774_RS07915	COG3290	protein histidine kinase activity
BS11774_RS07920	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BS11774_RS07925	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BS11774_RS07930	COG1733	regulation of RNA biosynthetic process
BS11774_RS07935	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BS11774_RS07940	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BS11774_RS07945	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BS11774_RS07950	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
BS11774_RS07955	COG2814	Major facilitator Superfamily
BS11774_RS07965	COG0697	spore germination
BS11774_RS07970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS11774_RS07980	COG2364	Membrane
BS11774_RS07985	COG1126	abc transporter atp-binding protein
BS11774_RS07990	COG0765	amino acid transport
BS11774_RS07995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BS11774_RS08000	COG0583	DNA-binding transcription factor activity
BS11774_RS08005	COG0163	prenyltransferase activity
BS11774_RS08010	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BS11774_RS08025	COG0596	Alpha beta hydrolase
BS11774_RS08030	COG3104	oligopeptide transport
BS11774_RS08035	COG5434	Belongs to the glycosyl hydrolase 28 family
BS11774_RS08045	COG0697	spore germination
BS11774_RS08055	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BS11774_RS08060	COG1136	(ABC) transporter
BS11774_RS08065	COG0577	efflux transmembrane transporter activity
BS11774_RS08070	COG0745	RESPONSE REGULATOR receiver
BS11774_RS08075	COG5002	protein histidine kinase activity
BS11774_RS08075	COG3850	Histidine kinase
BS11774_RS08080	COG0457	Tetratricopeptide repeat
BS11774_RS08100	COG0527	aspartate kinase activity
BS11774_RS08105	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS11774_RS08110	COG4605	iron ion homeostasis
BS11774_RS08115	COG4604	ABC transporter, ATP-binding protein
BS11774_RS08120	COG4607	ABC-type enterochelin transport system periplasmic component
BS11774_RS08125	COG2814	Major facilitator Superfamily
BS11774_RS08130	COG1309	transcriptional regulator
BS11774_RS08135	COG0778	Nitroreductase
BS11774_RS08140	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BS11774_RS08145	COG0640	Transcriptional regulator
BS11774_RS08150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS11774_RS08155	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BS11774_RS08160	COG1012	belongs to the aldehyde dehydrogenase family
BS11774_RS08165	COG4975	Glucose uptake
BS11774_RS08170	COG1028	Short-chain dehydrogenase reductase Sdr
BS11774_RS08175	COG4549	nuclear export factor GLE1
BS11774_RS08180	COG2372	response to copper ion
BS11774_RS08180	COG1276	copper resistance
BS11774_RS08185	COG1349	DNA-binding transcription factor activity
BS11774_RS08195	COG2213	PTS system mannitol-specific
BS11774_RS08200	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS11774_RS08205	COG0246	Mannitol dehydrogenase
BS11774_RS08210	COG0473	3-isopropylmalate dehydrogenase activity
BS11774_RS08215	COG0681	Belongs to the peptidase S26 family
BS11774_RS08220	COG0412	Dienelactone hydrolase
BS11774_RS08225	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BS11774_RS08235	COG0561	phosphatase activity
BS11774_RS08240	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BS11774_RS08245	COG1914	H( )-stimulated, divalent metal cation uptake system
BS11774_RS08250	COG4336	lyase activity
BS11774_RS08255	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BS11774_RS08260	COG1984	allophanate hydrolase subunit 2
BS11774_RS08265	COG1414	Transcriptional regulator
BS11774_RS08270	COG2755	lipolytic protein G-D-S-L family
BS11774_RS08280	COG2329	Antibiotic biosynthesis monooxygenase
BS11774_RS08285	COG0768	penicillin binding
BS11774_RS08290	COG4989	oxidoreductase activity
BS11774_RS08295	COG3711	transcriptional antiterminator
BS11774_RS08300	COG0318	PFAM AMP-dependent synthetase and ligase
BS11774_RS08305	COG2226	methyltransferase
BS11774_RS08310	COG1028	Short-chain dehydrogenase reductase Sdr
BS11774_RS08315	COG1917	Cupin 2, conserved barrel domain protein
BS11774_RS08320	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS11774_RS08325	COG3871	stress protein (general stress protein 26)
BS11774_RS08335	COG2814	Major facilitator Superfamily
BS11774_RS08340	COG1522	sequence-specific DNA binding
BS11774_RS08345	COG0551	DNA topoisomerase type I activity
BS11774_RS08345	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BS11774_RS08360	COG5298	Protein conserved in bacteria
BS11774_RS08365	COG1215	transferase activity, transferring glycosyl groups
BS11774_RS08375	COG0531	amino acid
BS11774_RS08380	COG0494	nUDIX hydrolase
BS11774_RS08385	COG0028	Belongs to the TPP enzyme family
BS11774_RS08400	COG1914	H( )-stimulated, divalent metal cation uptake system
BS11774_RS08405	COG2261	transglycosylase associated protein
BS11774_RS08410	COG4876	unkown
BS11774_RS08415	COG2217	Heavy metal translocating P-type atpase
BS11774_RS08420	COG3729	General stress protein
BS11774_RS08425	COG0662	Cupin 2, conserved barrel domain protein
BS11774_RS08430	COG2329	Antibiotic biosynthesis monooxygenase
BS11774_RS08435	COG3546	catalase activity
BS11774_RS08445	COG3290	protein histidine kinase activity
BS11774_RS08450	COG4565	transcriptional regulatory protein
BS11774_RS08455	COG1301	dicarboxylic acid transport
BS11774_RS08460	COG0628	permease
BS11774_RS08465	COG1131	(ABC) transporter
BS11774_RS08470	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BS11774_RS08480	COG1960	acyl-CoA dehydrogenase activity
BS11774_RS08495	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BS11774_RS08500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS11774_RS08505	COG1181	Belongs to the D-alanine--D-alanine ligase family
BS11774_RS08510	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BS11774_RS08520	COG0513	Belongs to the DEAD box helicase family
BS11774_RS08525	COG3402	PFAM membrane-flanked domain
BS11774_RS08530	COG3428	Bacterial PH domain
BS11774_RS08535	COG0705	Rhomboid family
BS11774_RS08540	COG0736	holo-[acyl-carrier-protein] synthase activity
BS11774_RS08545	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BS11774_RS08550	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BS11774_RS08555	COG0864	Transcriptional regulator
BS11774_RS08560	COG2337	Toxic component of a toxin-antitoxin (TA) module
BS11774_RS08565	COG1366	Belongs to the anti-sigma-factor antagonist family
BS11774_RS08570	COG1366	Belongs to the anti-sigma-factor antagonist family
BS11774_RS08575	COG2172	sigma factor antagonist activity
BS11774_RS08580	COG2208	phosphoserine phosphatase activity
BS11774_RS08585	COG1366	Belongs to the anti-sigma-factor antagonist family
BS11774_RS08590	COG2172	sigma factor antagonist activity
BS11774_RS08595	COG1191	sigma factor activity
BS11774_RS08600	COG2208	phosphoserine phosphatase activity
BS11774_RS08605	COG2183	response to ionizing radiation
BS11774_RS08615	COG3091	SprT-like family
BS11774_RS08680	COG1191	sigma factor activity
BS11774_RS08710	COG0582	viral genome integration into host DNA
BS11774_RS08715	COG2856	Zn peptidase
BS11774_RS08720	COG1396	sequence-specific DNA binding
BS11774_RS08750	COG3328	transposase activity
BS11774_RS08755	COG1329	Transcriptional regulator
BS11774_RS08765	COG0697	spore germination
BS11774_RS08770	COG1917	Cupin 2, conserved barrel domain protein
BS11774_RS08770	COG2207	Transcriptional regulator
BS11774_RS08775	COG0697	spore germination
BS11774_RS08780	COG2207	Transcriptional regulator
BS11774_RS08780	COG3708	Transcriptional regulator
BS11774_RS08785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS11774_RS08800	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
BS11774_RS08815	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS11774_RS08820	COG1309	transcriptional regulator
BS11774_RS08825	COG0697	spore germination
BS11774_RS08830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS11774_RS08835	COG2030	dehydratase
BS11774_RS08845	COG1733	regulation of RNA biosynthetic process
BS11774_RS08850	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BS11774_RS08855	COG0640	Transcriptional regulator
BS11774_RS08860	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BS11774_RS08865	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BS11774_RS08870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS11774_RS08875	COG0697	spore germination
BS11774_RS08880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS11774_RS08885	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BS11774_RS08890	COG0640	Transcriptional regulator
BS11774_RS08895	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BS11774_RS08925	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BS11774_RS08935	COG0346	lactoylglutathione lyase activity
BS11774_RS08940	COG2259	Doxx family
BS11774_RS08945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS11774_RS08965	COG2323	membrane
BS11774_RS08970	COG0071	Belongs to the small heat shock protein (HSP20) family
BS11774_RS08985	COG1309	transcriptional regulator
BS11774_RS08995	COG0456	acetyltransferase
BS11774_RS09005	COG1113	amino acid transport
BS11774_RS09010	COG2318	DinB family
BS11774_RS09015	COG1846	Transcriptional regulator
BS11774_RS09020	COG2409	Drug exporters of the RND superfamily
BS11774_RS09020	COG1033	growth of symbiont in host cell
BS11774_RS09025	COG0778	Nitroreductase
BS11774_RS09030	COG1846	Transcriptional regulator
BS11774_RS09035	COG2814	Major facilitator Superfamily
BS11774_RS09045	COG0730	response to heat
BS11774_RS09050	COG1802	Transcriptional regulator
BS11774_RS09055	COG1388	LysM domain
BS11774_RS09055	COG3858	chitin binding
BS11774_RS09070	COG1785	Belongs to the alkaline phosphatase family
BS11774_RS09075	COG5646	InterPro IPR014922
BS11774_RS09085	COG0454	-acetyltransferase
BS11774_RS09090	COG1078	dGTPase activity
BS11774_RS09095	COG1388	LysM domain
BS11774_RS09100	COG2814	Major facilitator Superfamily
BS11774_RS09105	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BS11774_RS09110	COG1447	Phosphotransferase system cellobiose-specific component IIA
BS11774_RS09115	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BS11774_RS09120	COG2723	6-phospho-beta-galactosidase activity
BS11774_RS09125	COG2188	Transcriptional regulator
BS11774_RS09130	COG1940	carbohydrate kinase activity
BS11774_RS09135	COG1482	cell wall glycoprotein biosynthetic process
BS11774_RS09140	COG4124	Belongs to the glycosyl hydrolase 26 family
BS11774_RS09185	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BS11774_RS09190	COG0802	atpase or kinase
BS11774_RS09195	COG1214	PFAM Peptidase M22, glycoprotease
BS11774_RS09200	COG0456	acetyltransferase
BS11774_RS09205	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BS11774_RS09210	COG0488	(ABC) transporter
BS11774_RS09215	COG0315	cyclic pyranopterin monophosphate synthase activity
BS11774_RS09220	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BS11774_RS09225	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BS11774_RS09230	COG0805	protein transport
BS11774_RS09245	COG1266	CAAX protease self-immunity
BS11774_RS09255	COG0459	protein refolding
BS11774_RS09265	COG1073	alpha beta
BS11774_RS09270	COG0457	Tetratricopeptide repeat
BS11774_RS09275	COG1063	alcohol dehydrogenase
BS11774_RS09280	COG2211	Major facilitator Superfamily
BS11774_RS09285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BS11774_RS09290	COG1842	Phage shock protein A
BS11774_RS09295	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BS11774_RS09300	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BS11774_RS09305	COG4260	virion core protein, lumpy skin disease virus
BS11774_RS09320	COG2814	Major facilitator Superfamily
BS11774_RS09325	COG1063	alcohol dehydrogenase
BS11774_RS09330	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BS11774_RS09335	COG0823	Involved in the tonB-independent uptake of proteins
BS11774_RS09355	COG2267	carboxylic ester hydrolase activity
BS11774_RS09365	COG2132	Multicopper oxidase
BS11774_RS09370	COG1113	amino acid transport
BS11774_RS09380	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BS11774_RS09385	COG0714	Associated with various cellular activities
BS11774_RS09390	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BS11774_RS09395	COG1305	Transglutaminase-like
BS11774_RS09400	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BS11774_RS09400	COG0519	Catalyzes the synthesis of GMP from XMP
BS11774_RS09415	COG2252	PERMEase
BS11774_RS09420	COG3064	Membrane
BS11774_RS09430	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BS11774_RS09440	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BS11774_RS09445	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BS11774_RS09450	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BS11774_RS09455	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BS11774_RS09460	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BS11774_RS09465	COG0047	phosphoribosylformylglycinamidine synthase activity
BS11774_RS09470	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BS11774_RS09475	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BS11774_RS09480	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BS11774_RS09485	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BS11774_RS09490	COG0138	bifunctional purine biosynthesis protein purh
BS11774_RS09495	COG0151	Belongs to the GarS family
BS11774_RS09500	COG1522	sequence-specific DNA binding
BS11774_RS09515	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BS11774_RS09520	COG1470	cell adhesion involved in biofilm formation
BS11774_RS09525	COG4496	protein, YerC YecD
BS11774_RS09530	COG0069	glutamate synthase activity
BS11774_RS09535	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
BS11774_RS09540	COG0210	DNA helicase
BS11774_RS09545	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BS11774_RS09555	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BS11774_RS09560	COG1285	pathogenesis
BS11774_RS09565	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BS11774_RS09570	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BS11774_RS09575	COG0154	amidase activity
BS11774_RS09580	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BS11774_RS09585	COG1309	transcriptional regulator
BS11774_RS09590	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BS11774_RS09595	COG1597	lipid kinase activity
BS11774_RS09645	COG5444	nuclease activity
BS11774_RS09650	COG3391	amine dehydrogenase activity
BS11774_RS09655	COG0457	Tetratricopeptide repeat
BS11774_RS09665	COG0217	transcriptional regulatory protein
BS11774_RS09675	COG1309	transcriptional regulator
BS11774_RS09680	COG3631	Ketosteroid isomerase-related protein
BS11774_RS09685	COG0702	epimerase
BS11774_RS09700	COG3546	catalase activity
BS11774_RS09705	COG0454	-acetyltransferase
BS11774_RS09715	COG5578	integral membrane protein
BS11774_RS09720	COG2972	Histidine kinase
BS11774_RS09725	COG4753	response regulator
BS11774_RS09725	COG2207	Transcriptional regulator
BS11774_RS09730	COG1653	transport
BS11774_RS09735	COG1175	transmembrane transport
BS11774_RS09740	COG0395	ABC-type sugar transport system, permease component
BS11774_RS09745	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BS11774_RS09750	COG2207	Transcriptional regulator
BS11774_RS09755	COG2755	lipolytic protein G-D-S-L family
BS11774_RS09765	COG5578	integral membrane protein
BS11774_RS09770	COG3401	FG-GAP repeat protein
BS11774_RS09775	COG3401	FG-GAP repeat protein
BS11774_RS09780	COG2755	lipolytic protein G-D-S-L family
BS11774_RS09785	COG1874	Beta-galactosidase
BS11774_RS09795	COG1653	transport
BS11774_RS09800	COG4209	transmembrane transport
BS11774_RS09805	COG0395	ABC-type sugar transport system, permease component
BS11774_RS09815	COG2323	membrane
BS11774_RS09820	COG2329	Antibiotic biosynthesis monooxygenase
BS11774_RS09825	COG0346	lactoylglutathione lyase activity
BS11774_RS09840	COG5583	Uncharacterized small protein (DUF2292)
BS11774_RS09845	COG0670	Belongs to the BI1 family
BS11774_RS09860	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BS11774_RS09870	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BS11774_RS09870	COG2124	cytochrome p450
BS11774_RS09885	COG1368	sulfuric ester hydrolase activity
BS11774_RS09890	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BS11774_RS09895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BS11774_RS09900	COG1442	glycosyl transferase family 8
BS11774_RS09905	COG1216	Glycosyl transferase, family 2
BS11774_RS09910	COG1442	glycosyl transferase family 8
BS11774_RS09915	COG2223	nitrite transmembrane transporter activity
BS11774_RS09920	COG1011	Hydrolase
BS11774_RS09925	COG0531	amino acid
BS11774_RS09930	COG1012	belongs to the aldehyde dehydrogenase family
BS11774_RS09935	COG0840	transmembrane signaling receptor activity
BS11774_RS09940	COG0488	(ABC) transporter
BS11774_RS09950	COG0789	Transcriptional regulator
BS11774_RS09970	COG0488	(ABC) transporter
BS11774_RS09975	COG0513	Belongs to the DEAD box helicase family
BS11774_RS09980	COG0456	acetyltransferase
BS11774_RS09985	COG2130	NADP-dependent
BS11774_RS09995	COG2211	Major facilitator Superfamily
BS11774_RS10000	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BS11774_RS10005	COG1120	ATPase activity
BS11774_RS10010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS11774_RS10015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS11774_RS10020	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BS11774_RS10035	COG3866	Pectate lyase
BS11774_RS10040	COG0471	metal ion transport
BS11774_RS10045	COG3290	protein histidine kinase activity
BS11774_RS10050	COG4565	transcriptional regulatory protein
BS11774_RS10055	COG3181	Tripartite tricarboxylate transporter family receptor
BS11774_RS10060	COG2851	Citrate transporter
BS11774_RS10065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BS11774_RS10070	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BS11774_RS10075	COG1254	Belongs to the acylphosphatase family
BS11774_RS10080	COG2258	MOSC domain
BS11774_RS10100	COG0024	Methionine aminopeptidase
BS11774_RS10105	COG1263	PTS System
BS11774_RS10105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS11774_RS10110	COG1368	sulfuric ester hydrolase activity
BS11774_RS10135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS11774_RS10135	COG1263	PTS System
BS11774_RS10140	COG0366	Alpha amylase catalytic
BS11774_RS10145	COG2188	Transcriptional regulator
BS11774_RS10150	COG0778	Nitroreductase
BS11774_RS10155	COG0737	Belongs to the 5'-nucleotidase family
BS11774_RS10160	COG0693	protein deglycase activity
BS11774_RS10165	COG2814	Major facilitator Superfamily
BS11774_RS10170	COG4840	Belongs to the UPF0435 family
BS11774_RS10175	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BS11774_RS10180	COG4980	gas vesicle protein
BS11774_RS10185	COG1295	ribonuclease BN
BS11774_RS10190	COG0477	Major facilitator Superfamily
BS11774_RS10195	COG0387	Pfam Sodium calcium exchanger
BS11774_RS10205	COG0668	transmembrane transport
BS11774_RS10210	COG0535	radical SAM domain protein
BS11774_RS10220	COG0726	polysaccharide deacetylase
BS11774_RS10225	COG2084	Dehydrogenase
BS11774_RS10230	COG0598	Magnesium transport protein CorA
BS11774_RS10235	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BS11774_RS10240	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BS11774_RS10245	COG3328	transposase activity
BS11774_RS10260	COG1132	(ABC) transporter
BS11774_RS10265	COG0515	serine threonine protein kinase
BS11774_RS10275	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BS11774_RS10280	COG4637	Psort location Cytoplasmic, score
BS11774_RS10295	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BS11774_RS10300	COG0022	dehydrogenase e1 component
BS11774_RS10305	COG0508	dehydrogenase complex catalyzes the overall conversion of
BS11774_RS10310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BS11774_RS10315	COG3284	Transcriptional regulator
BS11774_RS10345	COG4842	Belongs to the WXG100 family
BS11774_RS10350	COG1486	melibiose metabolic process
BS11774_RS10355	COG1737	Transcriptional regulator
BS11774_RS10360	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS11774_RS10360	COG1263	PTS System
BS11774_RS10365	COG1132	(ABC) transporter
BS11774_RS10370	COG1132	(ABC) transporter
BS11774_RS10375	COG2259	Doxx family
BS11774_RS10380	COG2514	catechol 2,3-dioxygenase activity
BS11774_RS10385	COG4585	Histidine kinase
BS11774_RS10390	COG2197	response regulator
BS11774_RS10395	COG1131	(ABC) transporter
BS11774_RS10400	COG1511	domain protein
BS11774_RS10400	COG0842	Transport permease protein
BS11774_RS10405	COG0842	Transport permease protein
BS11774_RS10410	COG1695	Transcriptional regulator
BS11774_RS10420	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BS11774_RS10425	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
BS11774_RS10430	COG2318	DinB family
BS11774_RS10435	COG2814	Major facilitator Superfamily
BS11774_RS10440	COG1846	Transcriptional regulator
BS11774_RS10445	COG0392	lysyltransferase activity
BS11774_RS10445	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BS11774_RS10450	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS11774_RS10455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS11774_RS10460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS11774_RS10465	COG0384	phenazine biosynthesis protein PhzF
BS11774_RS10470	COG0778	Nitroreductase
BS11774_RS10485	COG1090	epimerase
BS11774_RS10490	COG2137	regulation of response to DNA damage stimulus
BS11774_RS10500	COG2814	Major facilitator Superfamily
BS11774_RS10525	COG5658	integral membrane protein
BS11774_RS10530	COG0596	Alpha beta hydrolase
BS11774_RS10535	COG0463	Glycosyl transferase, family 2
BS11774_RS10540	COG4485	Bacterial membrane protein, YfhO
BS11774_RS10545	COG1988	membrane-bound metal-dependent
BS11774_RS10550	COG1194	a g-specific adenine glycosylase
BS11774_RS10560	COG1028	Short-chain dehydrogenase reductase Sdr
BS11774_RS10575	COG3557	Belongs to the UPF0374 family
BS11774_RS10580	COG1132	(ABC) transporter
BS11774_RS10585	COG4129	membrane
BS11774_RS10590	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BS11774_RS10595	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BS11774_RS10600	COG0735	belongs to the Fur family
BS11774_RS10725	COG5577	PFAM Coat F domain
BS11774_RS10730	COG3340	Belongs to the peptidase S51 family
BS11774_RS10735	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BS11774_RS10740	COG0277	FAD linked oxidase domain protein
BS11774_RS10750	COG0753	catalase activity
BS11774_RS10755	COG1116	anion transmembrane transporter activity
BS11774_RS10760	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BS11774_RS10765	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BS11774_RS10770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BS11774_RS10780	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BS11774_RS10790	COG1476	TRANSCRIPTIONal
BS11774_RS10800	COG3382	B3 4 domain protein
BS11774_RS10805	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BS11774_RS10815	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BS11774_RS10820	COG0789	Transcriptional regulator
BS11774_RS10825	COG1664	Polymer-forming cytoskeletal
BS11774_RS10830	COG1664	Polymer-forming cytoskeletal
BS11774_RS10835	COG2766	serine protein kinase
BS11774_RS10840	COG2718	Belongs to the UPF0229 family
BS11774_RS10845	COG1846	Transcriptional regulator
BS11774_RS10850	COG1566	PFAM secretion protein HlyD family protein
BS11774_RS10855	COG2814	Major facilitator Superfamily
BS11774_RS10860	COG0655	NAD(P)H dehydrogenase (quinone) activity
BS11774_RS10880	COG1725	Transcriptional regulator
BS11774_RS10885	COG1131	(ABC) transporter
BS11774_RS10890	COG1131	(ABC) transporter
BS11774_RS10895	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BS11774_RS10900	COG1278	Cold shock
BS11774_RS10910	COG1464	Belongs to the NlpA lipoprotein family
BS11774_RS10920	COG1823	symporter activity
BS11774_RS10945	COG0737	Belongs to the 5'-nucleotidase family
BS11774_RS10945	COG1525	nuclease
BS11774_RS10945	COG4085	toxin activity
BS11774_RS10950	COG3764	Sortase (surface protein transpeptidase)
BS11774_RS10955	COG0564	pseudouridine synthase activity
BS11774_RS10965	COG0517	IMP dehydrogenase activity
BS11774_RS10975	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BS11774_RS10980	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BS11774_RS10980	COG3153	acetyltransferase
BS11774_RS10985	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BS11774_RS10990	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BS11774_RS10995	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BS11774_RS11000	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BS11774_RS11005	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BS11774_RS11010	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BS11774_RS11015	COG2203	Gaf domain
BS11774_RS11015	COG4585	Histidine kinase
BS11774_RS11020	COG2197	response regulator
BS11774_RS11025	COG0431	NADPH-dependent FMN reductase
BS11774_RS11040	COG1388	LysM domain
BS11774_RS11040	COG0791	NLP P60 protein
BS11774_RS11045	COG1959	2 iron, 2 sulfur cluster binding
BS11774_RS11050	COG0668	transmembrane transport
BS11774_RS11055	COG2719	SpoVR family
BS11774_RS11060	COG1785	Belongs to the alkaline phosphatase family
BS11774_RS11065	COG1388	LysM domain
BS11774_RS11065	COG0791	NLP P60 protein
BS11774_RS11070	COG0583	DNA-binding transcription factor activity
BS11774_RS11075	COG0372	Belongs to the citrate synthase family
BS11774_RS11080	COG1028	Short-chain dehydrogenase reductase Sdr
BS11774_RS11085	COG0531	amino acid
BS11774_RS11090	COG0733	neurotransmitter:sodium symporter activity
BS11774_RS11095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS11774_RS11100	COG0456	acetyltransferase
BS11774_RS11115	COG1595	DNA-templated transcription, initiation
BS11774_RS11120	COG0667	Aldo Keto reductase
BS11774_RS11125	COG0204	Acyl-transferase
BS11774_RS11135	COG1253	flavin adenine dinucleotide binding
BS11774_RS11140	COG0789	Transcriptional regulator
BS11774_RS11145	COG0436	Aminotransferase
BS11774_RS11150	COG1253	flavin adenine dinucleotide binding
BS11774_RS11155	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BS11774_RS11160	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BS11774_RS11165	COG0584	glycerophosphoryl diester phosphodiesterase
BS11774_RS11175	COG0668	transmembrane transport
BS11774_RS11180	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BS11774_RS11185	COG0726	polysaccharide deacetylase
BS11774_RS11190	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BS11774_RS11195	COG1757	Na H antiporter
BS11774_RS11200	COG0589	response to stress
BS11774_RS11210	COG1132	(ABC) transporter
BS11774_RS11215	COG1132	(ABC) transporter
BS11774_RS11220	COG0702	epimerase
BS11774_RS11240	COG0189	ligase activity
BS11774_RS11245	COG0189	ligase activity
BS11774_RS11250	COG4399	Belongs to the UPF0754 family
BS11774_RS11255	COG3679	Belongs to the UPF0342 family
BS11774_RS11260	COG4335	DNA alkylation repair
BS11774_RS11265	COG0561	phosphatase activity
BS11774_RS11270	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BS11774_RS11275	COG0475	glutathione-regulated potassium exporter activity
BS11774_RS11280	COG0490	domain, Protein
BS11774_RS11290	COG1024	Enoyl-CoA hydratase
BS11774_RS11300	COG4152	abc transporter atp-binding protein
BS11774_RS11305	COG1668	transmembrane transport
BS11774_RS11310	COG0420	3'-5' exonuclease activity
BS11774_RS11315	COG4717	serine-type aminopeptidase activity
BS11774_RS11330	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BS11774_RS11360	COG1846	Transcriptional regulator
BS11774_RS11365	COG4980	gas vesicle protein
BS11774_RS11380	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BS11774_RS11385	COG0537	adenosine 5'-monophosphoramidase activity
BS11774_RS11390	COG1131	(ABC) transporter
BS11774_RS11395	COG4473	ABC transporter
BS11774_RS11405	COG1473	amidohydrolase
BS11774_RS11410	COG3069	C4-dicarboxylate transmembrane transporter activity
BS11774_RS11420	COG2329	Antibiotic biosynthesis monooxygenase
BS11774_RS11425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BS11774_RS11430	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BS11774_RS11435	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BS11774_RS11440	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BS11774_RS11445	COG1309	transcriptional regulator
BS11774_RS11450	COG1511	domain protein
BS11774_RS11455	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BS11774_RS11460	COG4377	Putative membrane peptidase family (DUF2324)
BS11774_RS11470	COG1363	Peptidase, m42
BS11774_RS11475	COG4405	Protein conserved in bacteria
BS11774_RS11480	COG1301	dicarboxylic acid transport
BS11774_RS11490	COG1234	tRNA 3'-trailer cleavage
BS11774_RS11495	COG0095	Lipoate-protein ligase
BS11774_RS11500	COG0702	epimerase
BS11774_RS11505	COG0318	PFAM AMP-dependent synthetase and ligase
BS11774_RS11515	COG0501	Belongs to the peptidase M48B family
BS11774_RS11520	COG1404	Belongs to the peptidase S8 family
BS11774_RS11525	COG0456	acetyltransferase
BS11774_RS11530	COG0604	alcohol dehydrogenase
BS11774_RS11535	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BS11774_RS11540	COG0406	alpha-ribazole phosphatase activity
BS11774_RS11545	COG0183	Belongs to the thiolase family
BS11774_RS11550	COG0318	PFAM AMP-dependent synthetase and ligase
BS11774_RS11555	COG1268	BioY protein
BS11774_RS11560	COG0840	transmembrane signaling receptor activity
BS11774_RS11565	COG0723	plastoquinol--plastocyanin reductase activity
BS11774_RS11565	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BS11774_RS11570	COG1028	Short-chain dehydrogenase reductase Sdr
BS11774_RS11580	COG4903	ComK protein
BS11774_RS11585	COG1028	Short-chain dehydrogenase reductase Sdr
BS11774_RS11595	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BS11774_RS11610	COG0398	Pfam SNARE associated Golgi protein
BS11774_RS11615	COG0681	Belongs to the peptidase S26 family
BS11774_RS11620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BS11774_RS11625	COG1846	Transcriptional regulator
BS11774_RS11630	COG0738	Major facilitator superfamily
BS11774_RS11640	COG0561	phosphatase activity
BS11774_RS11650	COG1609	Transcriptional regulator
BS11774_RS11655	COG3180	Ammonia monooxygenase
BS11774_RS11660	COG2814	Major facilitator Superfamily
BS11774_RS11660	COG0477	Major facilitator Superfamily
BS11774_RS11665	COG4533	DNA binding
BS11774_RS11675	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BS11774_RS11680	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BS11774_RS11685	COG1074	ATP-dependent DNA helicase activity
BS11774_RS11690	COG0420	3'-5' exonuclease activity
BS11774_RS11695	COG0419	ATPase involved in DNA repair
BS11774_RS11700	COG1403	HNH endonuclease
BS11774_RS11740	COG5337	Spore coat protein CotH
BS11774_RS11745	COG0179	Fumarylacetoacetate (FAA) hydrolase
BS11774_RS11755	COG1404	Belongs to the peptidase S8 family
BS11774_RS11765	COG0367	asparagine synthase
BS11774_RS11770	COG2318	DinB family
BS11774_RS11775	COG1562	ergosterol biosynthetic process
BS11774_RS11780	COG0534	Mate efflux family protein
BS11774_RS11785	COG1917	Cupin 2, conserved barrel domain protein
BS11774_RS11785	COG2207	Transcriptional regulator
BS11774_RS11790	COG1609	Transcriptional regulator
BS11774_RS11795	COG0673	inositol 2-dehydrogenase activity
BS11774_RS11800	COG2318	DinB family
BS11774_RS11805	COG1279	arginine transmembrane transporter activity
BS11774_RS11810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS11774_RS11815	COG1357	PFAM Pentapeptide repeats (8 copies)
BS11774_RS11820	COG2267	carboxylic ester hydrolase activity
BS11774_RS11830	COG0529	Catalyzes the synthesis of activated sulfate
BS11774_RS11835	COG2046	Belongs to the sulfate adenylyltransferase family
BS11774_RS11840	COG0175	sulfate reduction
BS11774_RS11845	COG2045	Belongs to the ComB family
BS11774_RS11850	COG1809	phosphosulfolactate synthase activity
BS11774_RS11855	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BS11774_RS11860	COG4948	Mandelate Racemase Muconate Lactonizing
BS11774_RS11875	COG0860	N-Acetylmuramoyl-L-alanine amidase
BS11774_RS11895	COG3546	catalase activity
BS11774_RS11915	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BS11774_RS11930	COG2323	membrane
BS11774_RS11940	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BS11774_RS11945	COG2323	membrane
BS11774_RS11950	COG2814	Major facilitator Superfamily
BS11774_RS11955	COG0454	-acetyltransferase
BS11774_RS11960	COG2153	protein acetylation
BS11774_RS11965	COG0646	methionine synthase
BS11774_RS11965	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BS11774_RS11970	COG1666	GTP binding
BS11774_RS11975	COG2996	Protein conserved in bacteria
BS11774_RS11995	COG1695	Transcriptional regulator
BS11774_RS12010	COG3227	Zinc metalloprotease (Elastase)
BS11774_RS12015	COG1307	EDD domain protein, DegV family
BS11774_RS12020	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BS11774_RS12035	COG0561	phosphatase activity
BS11774_RS12040	COG1073	alpha beta
BS11774_RS12045	COG2151	metal-sulfur cluster biosynthetic enzyme
BS11774_RS12055	COG0277	FAD linked oxidase domain protein
BS11774_RS12065	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BS11774_RS12070	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BS11774_RS12080	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BS11774_RS12085	COG0505	Belongs to the CarA family
BS11774_RS12090	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BS11774_RS12095	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BS11774_RS12110	COG2267	carboxylic ester hydrolase activity
BS11774_RS12120	COG1744	ABC transporter substrate-binding protein PnrA-like
BS11774_RS12135	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BS11774_RS12140	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BS11774_RS12145	COG5504	Zn-dependent protease
BS11774_RS12150	COG0444	Belongs to the ABC transporter superfamily
BS11774_RS12155	COG4608	Belongs to the ABC transporter superfamily
BS11774_RS12165	COG0601	transmembrane transport
BS11774_RS12170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BS11774_RS12180	COG0180	Tryptophanyl-tRNA synthetase
BS11774_RS12190	COG0601	transmembrane transport
BS11774_RS12195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BS11774_RS12200	COG0444	Belongs to the ABC transporter superfamily
BS11774_RS12205	COG4608	Belongs to the ABC transporter superfamily
BS11774_RS12210	COG2814	Major facilitator Superfamily
BS11774_RS12215	COG0456	acetyltransferase
BS11774_RS12220	COG1393	Belongs to the ArsC family
BS11774_RS12225	COG0861	Integral membrane protein TerC family
BS11774_RS12235	COG4862	establishment of competence for transformation
BS11774_RS12245	COG4469	Competence protein
BS11774_RS12250	COG1164	Oligoendopeptidase f
BS11774_RS12265	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BS11774_RS12270	COG2346	COG2346, Truncated hemoglobins
BS11774_RS12275	COG0741	lytic transglycosylase activity
BS11774_RS12280	COG4116	CYTH
BS11774_RS12290	COG2357	RelA SpoT domain protein
BS11774_RS12295	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BS11774_RS12300	COG0564	pseudouridine synthase activity
BS11774_RS12305	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BS11774_RS12310	COG0569	domain protein
BS11774_RS12310	COG0475	glutathione-regulated potassium exporter activity
BS11774_RS12315	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BS11774_RS12320	COG0352	thiamine-phosphate diphosphorylase activity
BS11774_RS12325	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BS11774_RS12330	COG2104	thiamine diphosphate biosynthetic process
BS11774_RS12335	COG2022	thiamine diphosphate biosynthetic process
BS11774_RS12340	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BS11774_RS12345	COG0351	phosphomethylpyrimidine kinase
BS11774_RS12350	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BS11774_RS12405	COG0210	DNA helicase
BS11774_RS12420	COG2153	protein acetylation
BS11774_RS12425	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BS11774_RS12430	COG2382	esterase
BS11774_RS12435	COG0626	cystathionine gamma-synthase activity
BS11774_RS12440	COG0626	cystathionine gamma-synthase activity
BS11774_RS12445	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS11774_RS12450	COG5505	Protein of unknown function (DUF819)
BS11774_RS12485	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BS11774_RS12490	COG1028	Short-chain dehydrogenase reductase Sdr
BS11774_RS12500	COG3711	transcriptional antiterminator
BS11774_RS12500	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS11774_RS12505	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS11774_RS12505	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BS11774_RS12505	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BS11774_RS12510	COG1482	cell wall glycoprotein biosynthetic process
BS11774_RS12520	COG3328	transposase activity
BS11774_RS12530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS11774_RS12540	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BS11774_RS12560	COG0109	protoheme IX farnesyltransferase activity
BS11774_RS12570	COG0726	polysaccharide deacetylase
BS11774_RS12585	COG5504	Zn-dependent protease
BS11774_RS12590	COG2205	protein histidine kinase activity
BS11774_RS12600	COG3383	formate dehydrogenase (NAD+) activity
BS11774_RS12605	COG2427	Protein of unknown function (DUF1641)
BS11774_RS12615	COG1051	belongs to the nudix hydrolase family
BS11774_RS12625	COG2124	cytochrome p450
BS11774_RS12630	COG1819	glycosyl
BS11774_RS12640	COG1587	Uroporphyrinogen-III synthase
BS11774_RS12645	COG0390	transport system, permease component
BS11774_RS12650	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BS11774_RS12655	COG0697	spore germination
BS11774_RS12660	COG4297	protein containing double-stranded beta helix domain
BS11774_RS12670	COG1252	NADH dehydrogenase
BS11774_RS12675	COG1904	glucuronate isomerase
BS11774_RS12680	COG2211	Major facilitator Superfamily
BS11774_RS12685	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BS11774_RS12695	COG1312	Catalyzes the dehydration of D-mannonate
BS11774_RS12700	COG1028	Short-chain dehydrogenase reductase Sdr
BS11774_RS12705	COG2271	Major facilitator Superfamily
BS11774_RS12710	COG1609	Transcriptional regulator
BS11774_RS12715	COG0246	Mannitol dehydrogenase
BS11774_RS12720	COG2721	sulfolactate sulfo-lyase activity
BS11774_RS12725	COG0730	response to heat
BS11774_RS12730	COG2318	DinB family
BS11774_RS12750	COG0457	Tetratricopeptide repeat
BS11774_RS12760	COG2350	Protein conserved in bacteria
BS11774_RS12765	COG5632	N-Acetylmuramoyl-L-alanine amidase
BS11774_RS12765	COG3409	Peptidoglycan-binding domain 1 protein
BS11774_RS12765	COG1388	LysM domain
BS11774_RS12775	COG4195	phage-related replication protein
BS11774_RS12780	COG3546	catalase activity
BS11774_RS12785	COG2856	Zn peptidase
BS11774_RS12790	COG1396	sequence-specific DNA binding
BS11774_RS12800	COG1522	sequence-specific DNA binding
BS11774_RS12805	COG1484	DNA-dependent DNA replication
BS11774_RS12825	COG1595	DNA-templated transcription, initiation
BS11774_RS12830	COG3728	DNA packaging
BS11774_RS12830	COG5484	DNA packaging
BS11774_RS12835	COG1783	phage Terminase large subunit
BS11774_RS12840	COG5518	Phage portal protein
BS11774_RS12845	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BS11774_RS12850	COG4653	Phage capsid family
BS11774_RS12900	COG3953	SLT domain
BS11774_RS12900	COG5412	phage tail tape measure protein
BS11774_RS12905	COG1652	LysM domain
BS11774_RS12910	COG4193	domain, Protein
BS11774_RS12920	COG3628	GPW Gp25 family protein
BS11774_RS12925	COG3299	homolog of phage Mu protein gp47
BS11774_RS12930	COG3778	Protein conserved in bacteria
BS11774_RS12970	COG3409	Peptidoglycan-binding domain 1 protein
BS11774_RS12970	COG5632	N-Acetylmuramoyl-L-alanine amidase
BS11774_RS12990	COG0306	phosphate transporter
BS11774_RS12995	COG1392	Phosphate transport regulator
BS11774_RS13000	COG0531	amino acid
BS11774_RS13005	COG0346	lactoylglutathione lyase activity
BS11774_RS13010	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BS11774_RS13015	COG0463	Glycosyl transferase, family 2
BS11774_RS13020	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BS11774_RS13025	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BS11774_RS13030	COG2362	D-Aminopeptidase
BS11774_RS13035	COG0601	transmembrane transport
BS11774_RS13040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BS11774_RS13045	COG0444	Belongs to the ABC transporter superfamily
BS11774_RS13050	COG4166	transmembrane transport
BS11774_RS13055	COG1619	proteins homologs of microcin C7 resistance protein MccF
BS11774_RS13060	COG4948	Mandelate Racemase Muconate Lactonizing
BS11774_RS13065	COG0791	NLP P60 protein
BS11774_RS13070	COG4608	Belongs to the ABC transporter superfamily
BS11774_RS13075	COG2706	6-phosphogluconolactonase activity
BS11774_RS13080	COG1834	amidinotransferase
BS11774_RS13085	COG1607	acyl-coa hydrolase
BS11774_RS13090	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BS11774_RS13090	COG1017	nitric oxide dioxygenase activity
BS11774_RS13100	COG2323	membrane
BS11774_RS13105	COG2318	DinB family
BS11774_RS13110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS11774_RS13115	COG2076	Multidrug Resistance protein
BS11774_RS13120	COG2076	Multidrug Resistance protein
BS11774_RS13125	COG0788	formyltetrahydrofolate deformylase activity
BS11774_RS13130	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BS11774_RS13135	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BS11774_RS13140	COG1764	response to oxidative stress
BS11774_RS13145	COG1846	Transcriptional regulator
BS11774_RS13150	COG1764	response to oxidative stress
BS11774_RS13160	COG0590	tRNA wobble adenosine to inosine editing
BS11774_RS13170	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BS11774_RS13175	COG1404	Belongs to the peptidase S8 family
BS11774_RS13180	COG1366	Belongs to the anti-sigma-factor antagonist family
BS11774_RS13185	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BS11774_RS13190	COG1122	ATPase activity
BS11774_RS13195	COG4721	ABC-type cobalt transport system, permease component
BS11774_RS13205	COG0745	RESPONSE REGULATOR receiver
BS11774_RS13210	COG5002	protein histidine kinase activity
BS11774_RS13210	COG3850	Histidine kinase
BS11774_RS13215	COG3212	peptidase
BS11774_RS13220	COG3212	peptidase
BS11774_RS13235	COG2239	Acts as a magnesium transporter
BS11774_RS13245	COG0789	Transcriptional regulator
BS11774_RS13260	COG1846	Transcriptional regulator
BS11774_RS13265	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BS11774_RS13275	COG1408	metallophosphoesterase
BS11774_RS13285	COG0463	Glycosyl transferase, family 2
BS11774_RS13290	COG3285	dna ligase
BS11774_RS13290	COG1793	dna ligase
BS11774_RS13295	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BS11774_RS13305	COG0586	Pfam SNARE associated Golgi protein
BS11774_RS13310	COG0861	Integral membrane protein TerC family
BS11774_RS13315	COG1191	sigma factor activity
BS11774_RS13335	COG0501	Belongs to the peptidase M48B family
BS11774_RS13340	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BS11774_RS13355	COG3594	Acyltransferase
BS11774_RS13360	COG5002	protein histidine kinase activity
BS11774_RS13365	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BS11774_RS13375	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BS11774_RS13380	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BS11774_RS13385	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BS11774_RS13390	COG0436	Aminotransferase
BS11774_RS13395	COG1850	ribulose-bisphosphate carboxylase activity
BS11774_RS13400	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
BS11774_RS13405	COG0235	Class ii aldolase
BS11774_RS13410	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BS11774_RS13415	COG3339	Conserved Protein
BS11774_RS13435	COG3852	Histidine kinase
BS11774_RS13445	COG1846	Transcriptional regulator
BS11774_RS13450	COG1360	Flagellar Motor Protein
BS11774_RS13455	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BS11774_RS13465	COG0542	response to heat
BS11774_RS13470	COG3949	Membrane
BS11774_RS13475	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BS11774_RS13480	COG0720	synthase
BS11774_RS13485	COG0602	queuosine metabolic process
BS11774_RS13490	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BS11774_RS13495	COG3328	transposase activity
BS11774_RS13505	COG1733	regulation of RNA biosynthetic process
BS11774_RS13510	COG1028	Short-chain dehydrogenase reductase Sdr
BS11774_RS13515	COG4641	Protein conserved in bacteria
BS11774_RS13515	COG1388	LysM domain
BS11774_RS13520	COG1388	LysM domain
BS11774_RS13525	COG3858	chitin binding
BS11774_RS13535	COG4873	Protein conserved in bacteria
BS11774_RS13550	COG3773	Cell wall hydrolase
BS11774_RS13555	COG2244	polysaccharide biosynthetic process
BS11774_RS13560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS11774_RS13565	COG2217	Heavy metal translocating P-type atpase
BS11774_RS13575	COG0006	proline dipeptidase activity
BS11774_RS13580	COG1609	Transcriptional regulator
BS11774_RS13585	COG3711	transcriptional antiterminator
BS11774_RS13590	COG2190	(PTS) system
BS11774_RS13590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS11774_RS13590	COG1263	PTS System
BS11774_RS13595	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS11774_RS13600	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BS11774_RS13610	COG1533	DNA photolyase activity
BS11774_RS13615	COG0456	acetyltransferase
BS11774_RS13620	COG0840	transmembrane signaling receptor activity
BS11774_RS13625	COG2084	Dehydrogenase
BS11774_RS13630	COG2340	Cysteine-rich secretory protein family
BS11774_RS13635	COG0768	penicillin binding
BS11774_RS13650	COG3328	transposase activity
BS11774_RS13660	COG0436	Aminotransferase
BS11774_RS13670	COG0835	chemotaxis
BS11774_RS13670	COG0784	Response regulator, receiver
BS11774_RS13680	COG2814	Major facilitator Superfamily
BS11774_RS13685	COG1376	ErfK ybiS ycfS ynhG family protein
BS11774_RS13690	COG1408	metallophosphoesterase
BS11774_RS13695	COG1028	Short-chain dehydrogenase reductase Sdr
BS11774_RS13700	COG2200	EAL domain
BS11774_RS13705	COG4703	Protein of unknown function (DUF1797)
BS11774_RS13710	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BS11774_RS13720	COG0517	IMP dehydrogenase activity
BS11774_RS13725	COG0583	DNA-binding transcription factor activity
BS11774_RS13730	COG0716	FMN binding
BS11774_RS13740	COG0716	FMN binding
BS11774_RS13745	COG2171	N-acyltransferase activity
BS11774_RS13750	COG1473	amidohydrolase
BS11774_RS13760	COG0668	transmembrane transport
BS11774_RS13765	COG0450	alkyl hydroperoxide reductase
BS11774_RS13770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS11774_RS13785	COG0746	molybdenum cofactor guanylyltransferase activity
BS11774_RS13790	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BS11774_RS13795	COG0303	'Molybdopterin
BS11774_RS13800	COG1763	Mo-molybdopterin cofactor biosynthetic process
BS11774_RS13805	COG0314	molybdopterin synthase activity
BS11774_RS13810	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BS11774_RS13815	COG1132	(ABC) transporter
BS11774_RS13820	COG1132	(ABC) transporter
BS11774_RS13830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BS11774_RS13835	COG1136	(ABC) transporter
BS11774_RS13840	COG0577	efflux transmembrane transporter activity
BS11774_RS13845	COG1349	DNA-binding transcription factor activity
BS11774_RS13850	COG1105	Belongs to the carbohydrate kinase PfkB family
BS11774_RS13855	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS11774_RS13855	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BS11774_RS13855	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BS11774_RS13860	COG0681	Belongs to the peptidase S26 family
BS11774_RS13870	COG0488	(ABC) transporter
BS11774_RS13875	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BS11774_RS13880	COG2309	aminopeptidase activity
BS11774_RS13890	COG1077	Cell shape determining protein MreB Mrl
BS11774_RS13895	COG2002	toxin-antitoxin pair type II binding
BS11774_RS13900	COG3852	Histidine kinase
BS11774_RS13905	COG2105	PFAM AIG2 family protein
BS11774_RS13905	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BS11774_RS13910	COG0569	domain protein
BS11774_RS13915	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BS11774_RS13920	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BS11774_RS13925	COG5503	Protein of unknown function (DUF1447)
BS11774_RS13930	COG0561	phosphatase activity
BS11774_RS13935	COG0242	peptide deformylase activity
BS11774_RS13945	COG0497	DNA recombination
BS11774_RS13950	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BS11774_RS13955	COG0022	dehydrogenase e1 component
BS11774_RS13960	COG0508	dehydrogenase complex catalyzes the overall conversion of
BS11774_RS13965	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BS11774_RS13970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS11774_RS13980	COG1982	Orn Lys Arg decarboxylase major
BS11774_RS13985	COG4476	Belongs to the UPF0223 family
BS11774_RS13990	COG4493	Belongs to the UPF0637 family
BS11774_RS14000	COG0483	inositol monophosphate 1-phosphatase activity
BS11774_RS14010	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BS11774_RS14035	COG1595	DNA-templated transcription, initiation
BS11774_RS14055	COG1217	gtp-binding protein TYPA
BS11774_RS14065	COG4896	Protein conserved in bacteria
BS11774_RS14075	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BS11774_RS14080	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BS11774_RS14085	COG2066	Belongs to the glutaminase family
BS11774_RS14090	COG4838	Belongs to the UPF0358 family
BS11774_RS14095	COG0772	Belongs to the SEDS family
BS11774_RS14100	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BS11774_RS14105	COG1612	heme a metabolic process
BS11774_RS14110	COG0109	protoheme IX farnesyltransferase activity
BS11774_RS14115	COG2010	Cytochrome c
BS11774_RS14115	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BS11774_RS14120	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BS11774_RS14125	COG1845	cytochrome c oxidase, subunit III
BS11774_RS14130	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BS11774_RS14135	COG3336	cytochrome c oxidase
BS11774_RS14145	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BS11774_RS14150	COG2340	Cysteine-rich secretory protein family
BS11774_RS14165	COG3679	Belongs to the UPF0342 family
BS11774_RS14170	COG4471	UPF0298 protein
BS11774_RS14175	COG0742	ribosomal rna small subunit methyltransferase
BS11774_RS14180	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BS11774_RS14185	COG3314	Sporulation integral membrane protein YlbJ
BS11774_RS14190	COG1752	Esterase of the alpha-beta hydrolase superfamily
BS11774_RS14195	COG3480	Lon protease (S16) C-terminal proteolytic domain
BS11774_RS14200	COG1323	Belongs to the UPF0348 family
BS11774_RS14210	COG1399	metal-binding, possibly nucleic acid-binding protein
BS11774_RS14225	COG0454	-acetyltransferase
BS11774_RS14230	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BS11774_RS14235	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BS11774_RS14240	COG2001	Belongs to the MraZ family
BS11774_RS14245	COG0275	rRNA processing
BS11774_RS14250	COG4839	cell division protein FtsL
BS11774_RS14255	COG0768	penicillin binding
BS11774_RS14260	COG0768	penicillin binding
BS11774_RS14265	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BS11774_RS14270	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BS11774_RS14275	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BS11774_RS14280	COG0772	Belongs to the SEDS family
BS11774_RS14285	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BS11774_RS14290	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BS11774_RS14295	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BS11774_RS14300	COG3879	Bacterial protein of unknown function (DUF881)
BS11774_RS14305	COG3879	Bacterial protein of unknown function (DUF881)
BS11774_RS14310	COG3856	small basic protein
BS11774_RS14315	COG0849	cell division
BS11774_RS14320	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BS11774_RS14325	COG4412	M6 family metalloprotease domain protein
BS11774_RS14325	COG1404	Belongs to the peptidase S8 family
BS11774_RS14335	COG1191	sigma factor activity
BS11774_RS14340	COG1191	sigma factor activity
BS11774_RS14345	COG1119	ATPase activity
BS11774_RS14350	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BS11774_RS14355	COG1873	PFAM PRC-barrel domain
BS11774_RS14360	COG1496	oxidoreductase activity
BS11774_RS14365	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BS11774_RS14370	COG1799	cell septum assembly
BS11774_RS14375	COG0762	integral membrane protein
BS11774_RS14380	COG2302	S4 RNA-binding domain
BS11774_RS14385	COG3599	regulation of cell shape
BS11774_RS14390	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BS11774_RS14395	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BS11774_RS14400	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BS11774_RS14405	COG0564	pseudouridine synthase activity
BS11774_RS14410	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BS11774_RS14415	COG2233	PERMEase
BS11774_RS14420	COG0540	Belongs to the ATCase OTCase family
BS11774_RS14425	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BS11774_RS14430	COG0505	Belongs to the CarA family
BS11774_RS14435	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BS11774_RS14440	COG0543	2 iron, 2 sulfur cluster binding
BS11774_RS14445	COG0167	dihydroorotate dehydrogenase activity
BS11774_RS14450	COG0284	orotidine-5'-phosphate decarboxylase activity
BS11774_RS14455	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BS11774_RS14460	COG0175	sulfate reduction
BS11774_RS14465	COG0306	phosphate transporter
BS11774_RS14470	COG2046	Belongs to the sulfate adenylyltransferase family
BS11774_RS14475	COG0529	Catalyzes the synthesis of activated sulfate
BS11774_RS14480	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BS11774_RS14485	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
BS11774_RS14490	COG1648	precorrin-2 dehydrogenase activity
BS11774_RS14495	COG1293	RNA-binding protein homologous to eukaryotic snRNP
BS11774_RS14500	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BS11774_RS14505	COG1561	YicC-like family, N-terminal region
BS11774_RS14515	COG0194	GDP metabolic process
BS11774_RS14520	COG1758	RNA polymerase activity
BS11774_RS14525	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BS11774_RS14530	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BS11774_RS14535	COG0242	peptide deformylase activity
BS11774_RS14540	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BS11774_RS14545	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BS11774_RS14545	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BS11774_RS14550	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BS11774_RS14555	COG0631	protein serine/threonine phosphatase activity
BS11774_RS14560	COG0515	serine threonine protein kinase
BS11774_RS14560	COG2815	serine threonine protein kinase
BS11774_RS14565	COG1162	GTPase activity
BS11774_RS14570	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BS11774_RS14575	COG1564	THIamine pyrophosphokinase
BS11774_RS14585	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BS11774_RS14590	COG1302	Protein conserved in bacteria
BS11774_RS14595	COG1461	Dihydroxyacetone kinase
BS11774_RS14600	COG1760	l-serine dehydratase
BS11774_RS14605	COG1760	l-serine dehydratase
BS11774_RS14610	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BS11774_RS14615	COG2050	protein possibly involved in aromatic compounds catabolism
BS11774_RS14615	COG1349	DNA-binding transcription factor activity
BS11774_RS14620	COG0416	fatty acid biosynthetic process
BS11774_RS14625	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BS11774_RS14630	COG1028	Short-chain dehydrogenase reductase Sdr
BS11774_RS14640	COG0571	ribonuclease III activity
BS11774_RS14645	COG1196	nuclear chromosome segregation
BS11774_RS14650	COG0552	protein localization to endoplasmic reticulum
BS11774_RS14660	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BS11774_RS14665	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BS11774_RS14670	COG0228	four-way junction DNA binding
BS11774_RS14675	COG1837	Belongs to the UPF0109 family
BS11774_RS14685	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BS11774_RS14690	COG0336	Belongs to the RNA methyltransferase TrmD family
BS11774_RS14695	COG0335	large ribosomal subunit rRNA binding
BS11774_RS14700	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BS11774_RS14705	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BS11774_RS14715	COG2257	FlhB HrpN YscU SpaS Family
BS11774_RS14720	COG0045	succinate-CoA ligase (ADP-forming) activity
BS11774_RS14725	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BS11774_RS14730	COG0758	DNA mediated transformation
BS11774_RS14735	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BS11774_RS14740	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BS11774_RS14745	COG4974	Belongs to the 'phage' integrase family
BS11774_RS14750	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BS11774_RS14755	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BS11774_RS14760	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BS11774_RS14765	COG1815	bacterial-type flagellum-dependent cell motility
BS11774_RS14770	COG1558	bacterial-type flagellum-dependent cell motility
BS11774_RS14775	COG1677	Flagellar hook-basal body complex protein FliE
BS11774_RS14780	COG1766	The M ring may be actively involved in energy transduction
BS11774_RS14785	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BS11774_RS14790	COG1317	bacterial-type flagellum organization
BS11774_RS14795	COG1157	protein secretion by the type III secretion system
BS11774_RS14800	COG2882	bacterial-type flagellum organization
BS11774_RS14805	COG3334	PFAM MgtE intracellular
BS11774_RS14810	COG3144	bacterial-type flagellum assembly
BS11774_RS14815	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BS11774_RS14820	COG4786	Flagellar basal body rod
BS11774_RS14825	COG1582	Flagellar protein (FlbD)
BS11774_RS14830	COG1580	Controls the rotational direction of flagella during chemotaxis
BS11774_RS14835	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BS11774_RS14840	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BS11774_RS14840	COG1776	CheC inhibitor of MCP methylation
BS11774_RS14845	COG2201	protein-glutamate methylesterase activity
BS11774_RS14850	COG3190	flagellar
BS11774_RS14855	COG1338	Plays a role in the flagellum-specific transport system
BS11774_RS14860	COG1987	bacterial-type flagellum assembly
BS11774_RS14865	COG1684	flagellar biosynthetic protein fliR
BS11774_RS14870	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BS11774_RS14875	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BS11774_RS14880	COG1419	protein localization to endoplasmic reticulum
BS11774_RS14885	COG0455	bacterial-type flagellum organization
BS11774_RS14890	COG2201	protein-glutamate methylesterase activity
BS11774_RS14895	COG0643	Histidine kinase
BS11774_RS14895	COG2198	Histidine kinase
BS11774_RS14900	COG0835	chemotaxis
BS11774_RS14905	COG1776	CheC inhibitor of MCP methylation
BS11774_RS14910	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BS11774_RS14915	COG1191	sigma factor activity
BS11774_RS14925	COG0052	Belongs to the universal ribosomal protein uS2 family
BS11774_RS14930	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BS11774_RS14935	COG0528	UMP kinase activity
BS11774_RS14940	COG0233	cytoplasmic translational termination
BS11774_RS14945	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BS11774_RS14950	COG4589	Belongs to the CDS family
BS11774_RS14955	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BS11774_RS14960	COG0750	zinc metalloprotease
BS11774_RS14965	COG0442	prolyl-tRNA aminoacylation
BS11774_RS14970	COG2176	DNA-directed DNA polymerase activity
BS11774_RS14975	COG0779	Required for maturation of 30S ribosomal subunits
BS11774_RS14980	COG0195	Participates in both transcription termination and antitermination
BS11774_RS14985	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BS11774_RS14990	COG1358	cellular component organization or biogenesis
BS11774_RS14995	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BS11774_RS15000	COG1550	Protein conserved in bacteria
BS11774_RS15005	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BS11774_RS15010	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BS11774_RS15015	COG0196	riboflavin kinase activity
BS11774_RS15020	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BS11774_RS15025	COG1185	polyribonucleotide nucleotidyltransferase activity
BS11774_RS15030	COG0726	polysaccharide deacetylase
BS11774_RS15035	COG0612	Peptidase, M16
BS11774_RS15040	COG1873	PFAM PRC-barrel domain
BS11774_RS15045	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BS11774_RS15050	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BS11774_RS15055	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BS11774_RS15060	COG0527	aspartate kinase activity
BS11774_RS15065	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BS11774_RS15070	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BS11774_RS15075	COG0740	serine-type endopeptidase activity
BS11774_RS15085	COG1674	ftsk spoiiie
BS11774_RS15085	COG4980	gas vesicle protein
BS11774_RS15090	COG2188	Transcriptional regulator
BS11774_RS15095	COG2814	Major facilitator Superfamily
BS11774_RS15100	COG0612	Peptidase, M16
BS11774_RS15105	COG0612	Peptidase, M16
BS11774_RS15110	COG0300	oxidoreductase activity
BS11774_RS15125	COG1426	Protein conserved in bacteria
BS11774_RS15130	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BS11774_RS15135	COG1546	Belongs to the CinA family
BS11774_RS15135	COG1058	Belongs to the CinA family
BS11774_RS15140	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BS11774_RS15145	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BS11774_RS15150	COG1418	mRNA catabolic process
BS11774_RS15155	COG1692	metallophosphoesterase
BS11774_RS15160	COG2359	stage V sporulation protein S
BS11774_RS15165	COG1063	alcohol dehydrogenase
BS11774_RS15170	COG0156	8-amino-7-oxononanoate synthase activity
BS11774_RS15175	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BS11774_RS15180	COG4550	Control of competence regulator ComK, YlbF/YmcA
BS11774_RS15190	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BS11774_RS15195	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BS11774_RS15210	COG3226	Transcriptional regulator
BS11774_RS15220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BS11774_RS15235	COG4195	phage-related replication protein
BS11774_RS15240	COG1764	response to oxidative stress
BS11774_RS15245	COG2076	Multidrug Resistance protein
BS11774_RS15250	COG2076	Multidrug Resistance protein
BS11774_RS15265	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BS11774_RS15270	COG1923	regulation of RNA biosynthetic process
BS11774_RS15285	COG1780	Probably involved in ribonucleotide reductase function
BS11774_RS15290	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BS11774_RS15295	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BS11774_RS15300	COG4112	unkown
BS11774_RS15305	COG0860	N-Acetylmuramoyl-L-alanine amidase
BS11774_RS15315	COG0464	growth
BS11774_RS15320	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BS11774_RS15325	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BS11774_RS15330	COG0789	Transcriptional regulator
BS11774_RS15335	COG0174	glutamine synthetase
BS11774_RS15390	COG4282	regulation of fungal-type cell wall biogenesis
BS11774_RS15400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS11774_RS15425	COG0135	phosphoribosylanthranilate isomerase activity
BS11774_RS15430	COG2211	Major facilitator Superfamily
BS11774_RS15435	COG3507	Belongs to the glycosyl hydrolase 43 family
BS11774_RS15440	COG1940	carbohydrate kinase activity
BS11774_RS15445	COG2115	Belongs to the xylose isomerase family
BS11774_RS15450	COG1070	Carbohydrate kinase
BS11774_RS15460	COG1525	nuclease
BS11774_RS15465	COG2814	Major facilitator Superfamily
BS11774_RS15470	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BS11774_RS15485	COG0756	dUTP diphosphatase activity
BS11774_RS15530	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BS11774_RS15545	COG3832	glyoxalase III activity
BS11774_RS15555	COG0697	spore germination
BS11774_RS15590	COG4195	phage-related replication protein
BS11774_RS15610	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BS11774_RS15615	COG1388	LysM domain
BS11774_RS15620	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BS11774_RS15625	COG4224	UPF0291 protein
BS11774_RS15630	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BS11774_RS15640	COG3763	UPF0154 protein
BS11774_RS15650	COG0785	Cytochrome C biogenesis protein
BS11774_RS15655	COG2201	protein-glutamate methylesterase activity
BS11774_RS15660	COG4846	Membrane protein involved in cytochrome C biogenesis
BS11774_RS15675	COG0071	Belongs to the small heat shock protein (HSP20) family
BS11774_RS15690	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BS11774_RS15695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS11774_RS15715	COG0824	Thioesterase
BS11774_RS15725	COG4841	protein insertion into membrane
BS11774_RS15730	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BS11774_RS15735	COG1832	CoA-binding protein
BS11774_RS15740	COG0187	DNA topoisomerase II activity
BS11774_RS15745	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BS11774_RS15755	COG1115	amino acid carrier protein
BS11774_RS15775	COG3507	Belongs to the glycosyl hydrolase 43 family
BS11774_RS15785	COG2246	polysaccharide biosynthetic process
BS11774_RS15790	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BS11774_RS15795	COG0586	Pfam SNARE associated Golgi protein
BS11774_RS15800	COG2404	hydrolase activity, acting on ester bonds
BS11774_RS15805	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BS11774_RS15810	COG1024	Enoyl-CoA hydratase
BS11774_RS15815	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BS11774_RS15820	COG0511	ligase activity, forming carbon-carbon bonds
BS11774_RS15825	COG0439	Biotin carboxylase
BS11774_RS15830	COG0318	PFAM AMP-dependent synthetase and ligase
BS11774_RS15835	COG1960	acyl-CoA dehydrogenase activity
BS11774_RS15850	COG1649	PFAM Uncharacterised BCR, COG1649
BS11774_RS15870	COG2027	D-alanyl-D-alanine carboxypeptidase
BS11774_RS15875	COG2017	converts alpha-aldose to the beta-anomer
BS11774_RS15880	COG0534	Mate efflux family protein
BS11774_RS15895	COG0582	viral genome integration into host DNA
BS11774_RS15900	COG0166	Belongs to the GPI family
BS11774_RS15905	COG0405	Gamma-glutamyltransferase
BS11774_RS15910	COG0583	DNA-binding transcription factor activity
BS11774_RS15915	COG0604	alcohol dehydrogenase
BS11774_RS15920	COG0493	'glutamate synthase
BS11774_RS15925	COG0067	glutamate synthase
BS11774_RS15925	COG0070	glutamate synthase
BS11774_RS15925	COG0069	glutamate synthase activity
BS11774_RS15930	COG0583	DNA-binding transcription factor activity
BS11774_RS15935	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BS11774_RS15940	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BS11774_RS15950	COG0300	oxidoreductase activity
BS11774_RS15955	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BS11774_RS15965	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS11774_RS15975	COG1070	Carbohydrate kinase
BS11774_RS16015	COG3328	transposase activity
BS11774_RS16025	COG5444	nuclease activity
BS11774_RS16040	COG3328	transposase activity
BS11774_RS16050	COG2368	4-hydroxyphenylacetate
BS11774_RS16055	COG4305	rare lipoprotein A
BS11774_RS16060	COG3619	membrane
BS11774_RS16065	COG3866	Pectate lyase
BS11774_RS16070	COG2135	peptidase activity
BS11774_RS16080	COG2140	Oxalate decarboxylase
BS11774_RS16110	COG2720	vancomycin resistance protein
BS11774_RS16120	COG3655	Transcriptional regulator
BS11774_RS16130	COG0583	DNA-binding transcription factor activity
BS11774_RS16145	COG0693	protein deglycase activity
BS11774_RS16150	COG2367	Beta-lactamase
BS11774_RS16175	COG3848	Pyruvate phosphate dikinase
BS11774_RS16175	COG0574	Belongs to the PEP-utilizing enzyme family
BS11774_RS16180	COG0726	polysaccharide deacetylase
BS11774_RS16190	COG2314	TM2 domain
BS11774_RS16195	COG1396	sequence-specific DNA binding
BS11774_RS16250	COG0457	Tetratricopeptide repeat
BS11774_RS16255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS11774_RS16265	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BS11774_RS16270	COG2226	methyltransferase
BS11774_RS16275	COG2211	Major facilitator Superfamily
BS11774_RS16290	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BS11774_RS16315	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS11774_RS16335	COG5444	nuclease activity
BS11774_RS16340	COG4282	regulation of fungal-type cell wall biogenesis
BS11774_RS16345	COG1231	oxidoreductase activity
BS11774_RS16350	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BS11774_RS16355	COG2207	Transcriptional regulator
BS11774_RS16355	COG0662	Cupin 2, conserved barrel domain protein
BS11774_RS16360	COG0456	acetyltransferase
BS11774_RS16365	COG1309	transcriptional regulator
BS11774_RS16370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BS11774_RS16375	COG3708	Transcriptional regulator
BS11774_RS16380	COG2378	regulation of single-species biofilm formation
BS11774_RS16390	COG0640	Transcriptional regulator
BS11774_RS16395	COG0741	lytic transglycosylase activity
BS11774_RS16400	COG2322	membrane
BS11774_RS16415	COG1619	proteins homologs of microcin C7 resistance protein MccF
BS11774_RS16420	COG3239	Fatty acid desaturase
BS11774_RS16425	COG4585	Histidine kinase
BS11774_RS16430	COG2197	response regulator
BS11774_RS16435	COG1388	LysM domain
BS11774_RS16435	COG3584	3D domain protein
BS11774_RS16440	COG0514	ATP-dependent DNA helicase (RecQ)
BS11774_RS16455	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BS11774_RS16460	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BS11774_RS16475	COG0071	Belongs to the small heat shock protein (HSP20) family
BS11774_RS16500	COG1012	belongs to the aldehyde dehydrogenase family
BS11774_RS16505	COG1657	PFAM Prenyltransferase squalene oxidase
BS11774_RS16515	COG0733	neurotransmitter:sodium symporter activity
BS11774_RS16520	COG0385	Bile acid
BS11774_RS16525	COG0508	dehydrogenase complex catalyzes the overall conversion of
BS11774_RS16530	COG0567	Dehydrogenase, E1 component
BS11774_RS16535	COG4548	von Willebrand factor, type A
BS11774_RS16540	COG0714	Associated with various cellular activities
BS11774_RS16545	COG2032	superoxide dismutase activity
BS11774_RS16550	COG1388	LysM domain
BS11774_RS16550	COG0791	NLP P60 protein
BS11774_RS16555	COG1819	glycosyl
BS11774_RS16560	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BS11774_RS16565	COG0534	Mate efflux family protein
BS11774_RS16570	COG1366	Belongs to the anti-sigma-factor antagonist family
BS11774_RS16575	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BS11774_RS16580	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BS11774_RS16590	COG2962	Rard protein
BS11774_RS16610	COG2610	gluconate transmembrane transporter activity
BS11774_RS16615	COG1942	4-Oxalocrotonate Tautomerase
BS11774_RS16620	COG1733	regulation of RNA biosynthetic process
BS11774_RS16625	COG0778	Nitroreductase
BS11774_RS16630	COG0400	carboxylic ester hydrolase activity
BS11774_RS16635	COG0346	lactoylglutathione lyase activity
BS11774_RS16645	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BS11774_RS16650	COG0793	Belongs to the peptidase S41A family
BS11774_RS16650	COG3409	Peptidoglycan-binding domain 1 protein
BS11774_RS16655	COG2226	methyltransferase
BS11774_RS16665	COG1876	peptidase activity
BS11774_RS16670	COG0813	purine-nucleoside phosphorylase activity
BS11774_RS16685	COG0671	phosphoesterase, PA-phosphatase related
BS11774_RS16710	COG4479	Belongs to the UPF0346 family
BS11774_RS16730	COG3331	DNA recombination
BS11774_RS16745	COG3328	transposase activity
BS11774_RS16790	COG0582	viral genome integration into host DNA
BS11774_RS16810	COG0741	lytic transglycosylase activity
BS11774_RS16810	COG0739	heme binding
BS11774_RS16810	COG1196	nuclear chromosome segregation
BS11774_RS16820	COG2433	Pfam Transposase IS66
BS11774_RS16835	COG5632	N-Acetylmuramoyl-L-alanine amidase
BS11774_RS16835	COG3409	Peptidoglycan-binding domain 1 protein
BS11774_RS16850	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BS11774_RS16855	COG0463	Glycosyl transferase, family 2
BS11774_RS16860	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS11774_RS16865	COG3271	cysteine-type peptidase activity
BS11774_RS16865	COG2274	protein secretion by the type I secretion system
BS11774_RS16880	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BS11774_RS16905	COG5444	nuclease activity
BS11774_RS16915	COG4282	regulation of fungal-type cell wall biogenesis
BS11774_RS16925	COG1525	nuclease
BS11774_RS16930	COG3328	transposase activity
BS11774_RS16945	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BS11774_RS16950	COG1509	lysine 2,3-aminomutase activity
BS11774_RS16955	COG0456	acetyltransferase
BS11774_RS16960	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BS11774_RS16965	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BS11774_RS16970	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BS11774_RS16975	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BS11774_RS16990	COG0456	acetyltransferase
BS11774_RS16995	COG0463	Glycosyl transferase, family 2
BS11774_RS17010	COG4641	Protein conserved in bacteria
BS11774_RS17015	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
BS11774_RS17020	COG1086	Polysaccharide biosynthesis protein
BS11774_RS17025	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BS11774_RS17030	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BS11774_RS17035	COG1846	Transcriptional regulator
BS11774_RS17040	COG0534	Mate efflux family protein
BS11774_RS17050	COG4698	Protein conserved in bacteria
BS11774_RS17055	COG2755	lipolytic protein G-D-S-L family
BS11774_RS17060	COG1999	signal sequence binding
BS11774_RS17070	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BS11774_RS17075	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BS11774_RS17080	COG1272	protein, Hemolysin III
BS11774_RS17085	COG0204	Acyl-transferase
BS11774_RS17090	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BS11774_RS17095	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BS11774_RS17105	COG2136	Putative SAM-dependent methyltransferase
BS11774_RS17105	COG2521	methyltransferase
BS11774_RS17115	COG0129	dihydroxy-acid dehydratase activity
BS11774_RS17120	COG1413	lyase activity
BS11774_RS17125	COG1418	mRNA catabolic process
BS11774_RS17130	COG0386	Belongs to the glutathione peroxidase family
BS11774_RS17135	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BS11774_RS17140	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BS11774_RS17150	COG1278	Cold shock
BS11774_RS17170	COG0328	RNA-DNA hybrid ribonuclease activity
BS11774_RS17175	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BS11774_RS17180	COG0328	RNA-DNA hybrid ribonuclease activity
BS11774_RS17190	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BS11774_RS17205	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BS11774_RS17215	COG1755	Isoprenylcysteine carboxyl methyltransferase
BS11774_RS17220	COG3424	synthase
BS11774_RS17225	COG2233	PERMEase
BS11774_RS17230	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BS11774_RS17235	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BS11774_RS17245	COG0800	Aldolase
BS11774_RS17250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BS11774_RS17255	COG1609	Transcriptional regulator
BS11774_RS17260	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BS11774_RS17265	COG1028	Short-chain dehydrogenase reductase Sdr
BS11774_RS17270	COG1199	ATP-dependent helicase activity
BS11774_RS17285	COG0116	Belongs to the methyltransferase superfamily
BS11774_RS17300	COG4474	Belongs to the UPF0398 family
BS11774_RS17315	COG3359	exonuclease
BS11774_RS17320	COG1205	dead DEAH box helicase
BS11774_RS17320	COG1111	helicase
BS11774_RS17325	COG2190	(PTS) system
BS11774_RS17330	COG0071	Belongs to the small heat shock protein (HSP20) family
BS11774_RS17365	COG3331	DNA recombination
BS11774_RS17370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BS11774_RS17370	COG4499	WXG100 protein secretion system (Wss), protein YukC
BS11774_RS17380	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BS11774_RS17385	COG3935	DnaD domain protein
BS11774_RS17390	COG0017	Asparaginyl-tRNA synthetase
BS11774_RS17395	COG0436	Aminotransferase
BS11774_RS17400	COG5353	protein conserved in bacteria
BS11774_RS17410	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BS11774_RS17410	COG1199	ATP-dependent helicase activity
BS11774_RS17415	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BS11774_RS17420	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BS11774_RS17425	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BS11774_RS17430	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BS11774_RS17430	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BS11774_RS17435	COG0617	tRNA 3'-terminal CCA addition
BS11774_RS17440	COG0438	transferase activity, transferring glycosyl groups
BS11774_RS17445	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BS11774_RS17450	COG1803	Methylglyoxal synthase
BS11774_RS17455	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BS11774_RS17460	COG1694	Mazg nucleotide pyrophosphohydrolase
BS11774_RS17465	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BS11774_RS17475	COG4347	Protein of unknown function (DUF1405)
BS11774_RS17480	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BS11774_RS17480	COG2010	Cytochrome c
BS11774_RS17485	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BS11774_RS17490	COG0723	plastoquinol--plastocyanin reductase activity
BS11774_RS17500	COG5582	Belongs to the UPF0302 family
BS11774_RS17505	COG0457	Tetratricopeptide repeat
BS11774_RS17510	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BS11774_RS17515	COG0287	Prephenate dehydrogenase
BS11774_RS17520	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BS11774_RS17525	COG0159	tryptophan synthase activity
BS11774_RS17530	COG0133	tryptophan synthase activity
BS11774_RS17535	COG0135	phosphoribosylanthranilate isomerase activity
BS11774_RS17545	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BS11774_RS17550	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BS11774_RS17555	COG4401	Chorismate mutase type I
BS11774_RS17560	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BS11774_RS17565	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BS11774_RS17570	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BS11774_RS17575	COG0105	UTP biosynthetic process
BS11774_RS17580	COG0142	geranyltranstransferase activity
BS11774_RS17585	COG2226	methyltransferase
BS11774_RS17590	COG0142	geranyltranstransferase activity
BS11774_RS17600	COG0302	gtp cyclohydrolase
BS11774_RS17605	COG0776	regulation of translation
BS11774_RS17610	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BS11774_RS17625	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BS11774_RS17630	COG1160	GTP binding
BS11774_RS17655	COG1304	FMN binding
BS11774_RS17660	COG0539	negative regulation of cytoplasmic translation
BS11774_RS17665	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BS11774_RS17675	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BS11774_RS17680	COG2959	enzyme of heme biosynthesis
BS11774_RS17685	COG3409	Peptidoglycan-binding domain 1 protein
BS11774_RS17685	COG3773	Cell wall hydrolase
BS11774_RS17690	COG2339	peptidase activity
BS11774_RS17695	COG0492	ferredoxin-NADP+ reductase activity
BS11774_RS17700	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BS11774_RS17705	COG4862	establishment of competence for transformation
BS11774_RS17710	COG1408	metallophosphoesterase
BS11774_RS17720	COG1388	LysM domain
BS11774_RS17725	COG1266	CAAX protease self-immunity
BS11774_RS17730	COG0514	ATP-dependent DNA helicase (RecQ)
BS11774_RS17735	COG4955	Helix-turn-helix domain
BS11774_RS17740	COG1141	Ferredoxin
BS11774_RS17745	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BS11774_RS17750	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BS11774_RS17760	COG0710	3-dehydroquinate dehydratase activity
BS11774_RS17770	COG1595	DNA-templated transcription, initiation
BS11774_RS17775	COG5002	protein histidine kinase activity
BS11774_RS17780	COG0745	RESPONSE REGULATOR receiver
BS11774_RS17785	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BS11774_RS17790	COG1333	cytochrome c biogenesis protein
BS11774_RS17795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS11774_RS17800	COG1187	pseudouridine synthase activity
BS11774_RS17810	COG2715	membrane protein required for spore maturation
BS11774_RS17815	COG1686	Belongs to the peptidase S11 family
BS11774_RS17825	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BS11774_RS17830	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BS11774_RS17835	COG1547	Domain of unknown function (DUF309)
BS11774_RS17840	COG0456	acetyltransferase
BS11774_RS17845	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BS11774_RS17850	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BS11774_RS17850	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BS11774_RS17855	COG0307	riboflavin synthase, alpha
BS11774_RS17860	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BS11774_RS17860	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BS11774_RS17870	COG0681	Belongs to the peptidase S26 family
BS11774_RS17875	COG3328	transposase activity
BS11774_RS17885	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
BS11774_RS17915	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BS11774_RS17925	COG4086	secreted protein
BS11774_RS17930	COG0019	diaminopimelate decarboxylase activity
BS11774_RS17935	COG0697	spore germination
BS11774_RS17950	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BS11774_RS17970	COG1191	sigma factor activity
BS11774_RS17975	COG2172	sigma factor antagonist activity
BS11774_RS17980	COG1366	Belongs to the anti-sigma-factor antagonist family
BS11774_RS17985	COG1686	Belongs to the peptidase S11 family
BS11774_RS17990	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BS11774_RS17995	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BS11774_RS18000	COG4974	Belongs to the 'phage' integrase family
BS11774_RS18010	COG0735	belongs to the Fur family
BS11774_RS18015	COG1300	Membrane
BS11774_RS18025	COG0281	malic enzyme
BS11774_RS18030	COG1757	Na H antiporter
BS11774_RS18035	COG1027	Aspartate ammonia-lyase
BS11774_RS18040	COG0252	asparaginase activity
BS11774_RS18045	COG1396	sequence-specific DNA binding
BS11774_RS18050	COG1379	DNA repair
BS11774_RS18055	COG0494	nUDIX hydrolase
BS11774_RS18065	COG0667	Aldo Keto reductase
BS11774_RS18075	COG1073	alpha beta
BS11774_RS18085	COG4918	Iron-sulphur cluster biosynthesis
BS11774_RS18090	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BS11774_RS18090	COG0456	acetyltransferase
BS11774_RS18095	COG2329	Antibiotic biosynthesis monooxygenase
BS11774_RS18100	COG0456	acetyltransferase
BS11774_RS18110	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BS11774_RS18120	COG2211	Major facilitator Superfamily
BS11774_RS18125	COG0346	lactoylglutathione lyase activity
BS11774_RS18130	COG1072	(Pantothenic acid kinase))
BS11774_RS18135	COG3048	D-serine ammonia-lyase activity
BS11774_RS18140	COG0300	oxidoreductase activity
BS11774_RS18145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BS11774_RS18150	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BS11774_RS18155	COG4187	Peptidase family M20/M25/M40
BS11774_RS18160	COG1902	pentaerythritol trinitrate reductase activity
BS11774_RS18165	COG0596	Alpha beta hydrolase
BS11774_RS18180	COG1234	tRNA 3'-trailer cleavage
BS11774_RS18185	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BS11774_RS18190	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BS11774_RS18195	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BS11774_RS18205	COG0706	membrane insertase activity
BS11774_RS18210	COG3361	conserved protein (COG2071)
BS11774_RS18215	COG2195	Cleaves the N-terminal amino acid of tripeptides
BS11774_RS18220	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BS11774_RS18225	COG0346	lactoylglutathione lyase activity
BS11774_RS18230	COG1376	ErfK ybiS ycfS ynhG family protein
BS11774_RS18235	COG4129	membrane
BS11774_RS18240	COG1126	abc transporter atp-binding protein
BS11774_RS18245	COG0765	amino acid transport
BS11774_RS18250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BS11774_RS18260	COG1597	lipid kinase activity
BS11774_RS18265	COG2814	Major facilitator Superfamily
BS11774_RS18270	COG4978	Transcriptional regulator
BS11774_RS18270	COG0789	Transcriptional regulator
BS11774_RS18275	COG0508	dehydrogenase complex catalyzes the overall conversion of
BS11774_RS18280	COG0022	dehydrogenase e1 component
BS11774_RS18285	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BS11774_RS18290	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BS11774_RS18295	COG3426	butyrate kinase activity
BS11774_RS18300	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BS11774_RS18305	COG0280	phosphate acetyltransferase
BS11774_RS18310	COG3829	transcription factor binding
BS11774_RS18310	COG3290	protein histidine kinase activity
BS11774_RS18320	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BS11774_RS18325	COG2079	MmgE PrpD family protein
BS11774_RS18330	COG0372	Belongs to the citrate synthase family
BS11774_RS18335	COG1960	acyl-CoA dehydrogenase activity
BS11774_RS18340	COG1250	3-hydroxyacyl-CoA dehydrogenase
BS11774_RS18345	COG0183	Belongs to the thiolase family
BS11774_RS18350	COG0584	glycerophosphoryl diester phosphodiesterase
BS11774_RS18355	COG0860	N-Acetylmuramoyl-L-alanine amidase
BS11774_RS18370	COG1902	pentaerythritol trinitrate reductase activity
BS11774_RS18375	COG0745	RESPONSE REGULATOR receiver
BS11774_RS18385	COG0750	zinc metalloprotease
BS11774_RS18390	COG0497	DNA recombination
BS11774_RS18395	COG1438	arginine binding
BS11774_RS18400	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BS11774_RS18405	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BS11774_RS18410	COG0142	geranyltranstransferase activity
BS11774_RS18415	COG1722	exodeoxyribonuclease VII activity
BS11774_RS18420	COG1570	exodeoxyribonuclease VII activity
BS11774_RS18425	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BS11774_RS18430	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BS11774_RS18435	COG1302	Protein conserved in bacteria
BS11774_RS18440	COG0439	Biotin carboxylase
BS11774_RS18445	COG0511	ligase activity, forming carbon-carbon bonds
BS11774_RS18485	COG3854	ATPases associated with a variety of cellular activities
BS11774_RS18495	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BS11774_RS18500	COG0006	proline dipeptidase activity
BS11774_RS18505	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BS11774_RS18515	COG3872	metal-dependent enzyme
BS11774_RS18525	COG1752	Esterase of the alpha-beta hydrolase superfamily
BS11774_RS18530	COG1321	iron dependent repressor
BS11774_RS18535	COG0095	Lipoate-protein ligase
BS11774_RS18540	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BS11774_RS18545	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BS11774_RS18550	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BS11774_RS18555	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BS11774_RS18560	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BS11774_RS18575	COG1396	sequence-specific DNA binding
BS11774_RS18585	COG0681	Belongs to the peptidase S26 family
BS11774_RS18610	COG4940	Competence protein ComGF
BS11774_RS18620	COG4970	Tfp pilus assembly protein FimT
BS11774_RS18625	COG4537	Required for transformation and DNA binding
BS11774_RS18630	COG1459	type II secretion system
BS11774_RS18635	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BS11774_RS18640	COG0517	IMP dehydrogenase activity
BS11774_RS18645	COG0598	Magnesium transport protein CorA
BS11774_RS18650	COG1253	flavin adenine dinucleotide binding
BS11774_RS18655	COG1366	Belongs to the anti-sigma-factor antagonist family
BS11774_RS18665	COG1393	Belongs to the ArsC family
BS11774_RS18675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BS11774_RS18685	COG0011	TIGRFAM Protein of
BS11774_RS18695	COG2866	Carboxypeptidase
BS11774_RS18700	COG1368	sulfuric ester hydrolase activity
BS11774_RS18705	COG1940	carbohydrate kinase activity
BS11774_RS18710	COG4483	Protein conserved in bacteria
BS11774_RS18715	COG0705	Rhomboid family
BS11774_RS18715	COG0457	Tetratricopeptide repeat
BS11774_RS18725	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BS11774_RS18735	COG0438	transferase activity, transferring glycosyl groups
BS11774_RS18750	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BS11774_RS18755	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BS11774_RS18760	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BS11774_RS18765	COG0581	inorganic phosphate transmembrane transporter activity
BS11774_RS18770	COG0573	inorganic phosphate transmembrane transporter activity
BS11774_RS18775	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BS11774_RS18780	COG0768	penicillin binding
BS11774_RS18785	COG0477	Major facilitator Superfamily
BS11774_RS18790	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BS11774_RS18795	COG2839	Protein conserved in bacteria
BS11774_RS18800	COG5521	maltodextrose utilization protein MalA
BS11774_RS18805	COG1388	LysM domain
BS11774_RS18810	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BS11774_RS18815	COG4709	membrane
BS11774_RS18820	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BS11774_RS18825	COG0735	belongs to the Fur family
BS11774_RS18830	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BS11774_RS18840	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BS11774_RS18845	COG0513	Belongs to the DEAD box helicase family
BS11774_RS18855	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BS11774_RS18860	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BS11774_RS18865	COG2384	SAM-dependent methyltransferase
BS11774_RS18870	COG2010	Cytochrome c
BS11774_RS18880	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BS11774_RS18885	COG0358	DNA primase activity
BS11774_RS18890	COG1671	Belongs to the UPF0178 family
BS11774_RS18895	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BS11774_RS18900	COG0517	IMP dehydrogenase activity
BS11774_RS18905	COG0751	glycine-tRNA ligase activity
BS11774_RS18910	COG0752	glycyl-tRNA synthetase alpha subunit
BS11774_RS18915	COG1381	Involved in DNA repair and RecF pathway recombination
BS11774_RS18925	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BS11774_RS18930	COG0295	cytidine deaminase activity
BS11774_RS18935	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BS11774_RS18940	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BS11774_RS18945	COG1480	7TM receptor with intracellular HD hydrolase
BS11774_RS18950	COG1702	phosphate starvation-inducible protein PhoH
BS11774_RS18955	COG0561	phosphatase activity
BS11774_RS18970	COG4864	UPF0365 protein
BS11774_RS18975	COG1030	water channel activity
BS11774_RS18980	COG1610	YqeY-like protein
BS11774_RS18990	COG1283	sodium-dependent phosphate transmembrane transporter activity
BS11774_RS18995	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BS11774_RS19000	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BS11774_RS19005	COG2264	protein methyltransferase activity
BS11774_RS19010	COG0484	heat shock protein binding
BS11774_RS19015	COG0443	Heat shock 70 kDa protein
BS11774_RS19020	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BS11774_RS19025	COG1420	regulation of RNA biosynthetic process
BS11774_RS19030	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BS11774_RS19035	COG0481	GTPase activity
BS11774_RS19045	COG0860	N-Acetylmuramoyl-L-alanine amidase
BS11774_RS19050	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BS11774_RS19055	COG0268	Binds directly to 16S ribosomal RNA
BS11774_RS19060	COG1466	dna polymerase III delta subunit
BS11774_RS19075	COG2333	competence protein COMEC
BS11774_RS19075	COG0658	competence protein
BS11774_RS19080	COG2131	deaminase
BS11774_RS19085	COG1596	polysaccharide export
BS11774_RS19085	COG1555	photosystem II stabilization
BS11774_RS19090	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BS11774_RS19095	COG2226	methyltransferase
BS11774_RS19100	COG0799	negative regulation of ribosome biogenesis
BS11774_RS19105	COG1713	HD superfamily hydrolase involved in NAD metabolism
BS11774_RS19110	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BS11774_RS19115	COG1534	Rna-binding protein
BS11774_RS19120	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BS11774_RS19125	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BS11774_RS19130	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BS11774_RS19140	COG2755	lipolytic protein G-D-S-L family
BS11774_RS19145	COG5632	N-Acetylmuramoyl-L-alanine amidase
BS11774_RS19145	COG3409	Peptidoglycan-binding domain 1 protein
BS11774_RS19150	COG0398	Pfam SNARE associated Golgi protein
BS11774_RS19175	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BS11774_RS19190	COG0604	alcohol dehydrogenase
BS11774_RS19200	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BS11774_RS19205	COG0798	PFAM Bile acid sodium symporter
BS11774_RS19210	COG0346	lactoylglutathione lyase activity
BS11774_RS19215	COG0640	Transcriptional regulator
BS11774_RS19220	COG3403	YqcI/YcgG family
BS11774_RS19225	COG0457	Tetratricopeptide repeat
BS11774_RS19240	COG5444	nuclease activity
BS11774_RS19245	COG4282	regulation of fungal-type cell wall biogenesis
BS11774_RS19275	COG3409	Peptidoglycan-binding domain 1 protein
BS11774_RS19275	COG5632	N-Acetylmuramoyl-L-alanine amidase
BS11774_RS19280	COG4824	toxin secretion phage lysis holin
BS11774_RS19310	COG3778	Protein conserved in bacteria
BS11774_RS19315	COG3299	homolog of phage Mu protein gp47
BS11774_RS19320	COG3628	GPW Gp25 family protein
BS11774_RS19330	COG4193	domain, Protein
BS11774_RS19335	COG1652	LysM domain
BS11774_RS19340	COG5280	Phage tail tape measure protein TP901
BS11774_RS19340	COG3953	SLT domain
BS11774_RS19400	COG4653	Phage capsid family
BS11774_RS19405	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BS11774_RS19415	COG2369	cell adhesion
BS11774_RS19420	COG5518	Phage portal protein
BS11774_RS19425	COG1783	phage Terminase large subunit
BS11774_RS19430	COG5484	DNA packaging
BS11774_RS19465	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
BS11774_RS19475	COG1484	DNA-dependent DNA replication
BS11774_RS19480	COG3935	DnaD domain protein
BS11774_RS19485	COG3723	Recombinational DNA repair protein, rece pathway
BS11774_RS19490	COG5377	YqaJ viral recombinase family
BS11774_RS19520	COG1476	TRANSCRIPTIONal
BS11774_RS19525	COG3620	sequence-specific DNA binding
BS11774_RS19550	COG0563	adenylate kinase activity
BS11774_RS19555	COG2856	Zn peptidase
BS11774_RS19575	COG4124	Belongs to the glycosyl hydrolase 26 family
BS11774_RS19580	COG0730	response to heat
BS11774_RS19585	COG0425	Belongs to the sulfur carrier protein TusA family
BS11774_RS19590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BS11774_RS19590	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BS11774_RS19600	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BS11774_RS19600	COG0425	Belongs to the sulfur carrier protein TusA family
BS11774_RS19605	COG2210	Belongs to the sulfur carrier protein TusA family
BS11774_RS19610	COG1937	Protein conserved in bacteria
BS11774_RS19625	COG0662	Cupin 2, conserved barrel domain protein
BS11774_RS19640	COG4978	Transcriptional regulator
BS11774_RS19640	COG0789	Transcriptional regulator
BS11774_RS19645	COG2814	Major facilitator Superfamily
BS11774_RS19650	COG0456	acetyltransferase
BS11774_RS19655	COG1253	flavin adenine dinucleotide binding
BS11774_RS19665	COG0697	spore germination
BS11774_RS19670	COG0583	DNA-binding transcription factor activity
BS11774_RS19675	COG2072	flavoprotein involved in K transport
BS11774_RS19680	COG1230	cation diffusion facilitator family transporter
BS11774_RS19690	COG1114	Component of the transport system for branched-chain amino acids
BS11774_RS19695	COG1687	branched-chain amino acid
BS11774_RS19700	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BS11774_RS19705	COG1522	sequence-specific DNA binding
BS11774_RS19715	COG2124	cytochrome p450
BS11774_RS19725	COG1335	isochorismatase
BS11774_RS19740	COG2318	DinB family
BS11774_RS19750	COG2070	2-Nitropropane dioxygenase
BS11774_RS19765	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BS11774_RS19795	COG0667	Aldo Keto reductase
BS11774_RS19800	COG2851	Citrate transporter
BS11774_RS19805	COG0583	DNA-binding transcription factor activity
BS11774_RS19810	COG2828	Protein conserved in bacteria
BS11774_RS19815	COG3409	Peptidoglycan-binding domain 1 protein
BS11774_RS19820	COG5566	PFAM Mor transcription activator
BS11774_RS19825	COG0596	Alpha beta hydrolase
BS11774_RS19830	COG4991	sh3 domain protein
BS11774_RS19835	COG4991	sh3 domain protein
BS11774_RS19850	COG5577	PFAM Coat F domain
BS11774_RS19855	COG1063	alcohol dehydrogenase
BS11774_RS19865	COG5577	PFAM Coat F domain
BS11774_RS19870	COG0789	Transcriptional regulator
BS11774_RS19880	COG1064	alcohol dehydrogenase
BS11774_RS19885	COG0693	protein deglycase activity
BS11774_RS19890	COG1621	beta-fructofuranosidase activity
BS11774_RS19895	COG3716	PTS system mannose fructose sorbose family IID component
BS11774_RS19900	COG3715	PTS system
BS11774_RS19905	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS11774_RS19910	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS11774_RS19915	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BS11774_RS19915	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BS11774_RS19925	COG1113	amino acid transport
BS11774_RS19930	COG1280	lysine exporter protein (LysE YggA)
BS11774_RS19935	COG1378	Sugar-specific transcriptional regulator TrmB
BS11774_RS19970	COG1595	DNA-templated transcription, initiation
BS11774_RS19980	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BS11774_RS19980	COG2755	lipolytic protein G-D-S-L family
BS11774_RS19995	COG2226	methyltransferase
BS11774_RS20010	COG2116	formate transmembrane transporter activity
BS11774_RS20015	COG5609	conserved protein (DUF2294)
BS11774_RS20020	COG3383	formate dehydrogenase (NAD+) activity
BS11774_RS20025	COG2427	Protein of unknown function (DUF1641)
BS11774_RS20035	COG0626	cystathionine gamma-synthase activity
BS11774_RS20040	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BS11774_RS20045	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BS11774_RS20050	COG2226	methyltransferase
BS11774_RS20065	COG0768	penicillin binding
BS11774_RS20070	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BS11774_RS20075	COG0572	uridine kinase
BS11774_RS20080	COG0826	peptidase U32
BS11774_RS20085	COG0826	peptidase U32
BS11774_RS20090	COG4122	O-methyltransferase activity
BS11774_RS20095	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BS11774_RS20100	COG3906	Belongs to the UPF0473 family
BS11774_RS20105	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BS11774_RS20110	COG4472	Bacterial protein of unknown function (DUF965)
BS11774_RS20115	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BS11774_RS20120	COG0628	permease
BS11774_RS20125	COG1126	abc transporter atp-binding protein
BS11774_RS20130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BS11774_RS20135	COG0765	amino acid transport
BS11774_RS20140	COG0765	amino acid transport
BS11774_RS20155	COG3881	PFAM PRC-barrel domain
BS11774_RS20160	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BS11774_RS20165	COG0457	Tetratricopeptide repeat
BS11774_RS20170	COG0482	sulfurtransferase activity
BS11774_RS20175	COG1104	cysteine desulfurase activity
BS11774_RS20180	COG1959	2 iron, 2 sulfur cluster binding
BS11774_RS20185	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BS11774_RS20190	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BS11774_RS20200	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BS11774_RS20205	COG0124	histidyl-tRNA synthetase
BS11774_RS20215	COG0860	N-Acetylmuramoyl-L-alanine amidase
BS11774_RS20215	COG3103	Sh3 type 3 domain protein
BS11774_RS20215	COG4991	sh3 domain protein
BS11774_RS20220	COG1490	D-aminoacyl-tRNA deacylase activity
BS11774_RS20225	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BS11774_RS20230	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BS11774_RS20235	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BS11774_RS20235	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BS11774_RS20240	COG5416	Lipopolysaccharide assembly protein A domain
BS11774_RS20245	COG0490	domain, Protein
BS11774_RS20250	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BS11774_RS20250	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BS11774_RS20260	COG2244	polysaccharide biosynthetic process
BS11774_RS20265	COG2323	membrane
BS11774_RS20275	COG1862	Preprotein translocase
BS11774_RS20280	COG0343	queuine tRNA-ribosyltransferase activity
BS11774_RS20285	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BS11774_RS20295	COG2255	four-way junction helicase activity
BS11774_RS20300	COG0632	four-way junction helicase activity
BS11774_RS20310	COG2814	Major facilitator Superfamily
BS11774_RS20315	COG0673	inositol 2-dehydrogenase activity
BS11774_RS20320	COG2112	serine threonine protein kinase
BS11774_RS20340	COG1115	amino acid carrier protein
BS11774_RS20345	COG0217	transcriptional regulatory protein
BS11774_RS20355	COG1388	LysM domain
BS11774_RS20360	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BS11774_RS20365	COG0157	Belongs to the NadC ModD family
BS11774_RS20370	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BS11774_RS20375	COG1104	cysteine desulfurase activity
BS11774_RS20380	COG1827	regulation of RNA biosynthetic process
BS11774_RS20385	COG0077	Prephenate dehydratase
BS11774_RS20390	COG4492	Belongs to the UPF0735 family
BS11774_RS20395	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BS11774_RS20400	COG3290	protein histidine kinase activity
BS11774_RS20410	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BS11774_RS20415	COG2868	ribosomal protein
BS11774_RS20420	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BS11774_RS20425	COG1994	Peptidase M50
BS11774_RS20430	COG0739	heme binding
BS11774_RS20435	COG2894	cell division
BS11774_RS20440	COG0850	regulation of cytokinetic process
BS11774_RS20445	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BS11774_RS20455	COG1077	Cell shape determining protein MreB Mrl
BS11774_RS20460	COG2003	Belongs to the UPF0758 family
BS11774_RS20465	COG0424	maF-like protein
BS11774_RS20475	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BS11774_RS20480	COG0285	dihydrofolate synthase activity
BS11774_RS20485	COG0525	valine-tRNA ligase activity
BS11774_RS20495	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BS11774_RS20500	COG1388	LysM domain
BS11774_RS20505	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BS11774_RS20510	COG0113	porphobilinogen synthase activity
BS11774_RS20515	COG1587	Uroporphyrinogen-III synthase
BS11774_RS20520	COG0181	hydroxymethylbilane synthase activity
BS11774_RS20525	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BS11774_RS20530	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BS11774_RS20540	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BS11774_RS20545	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BS11774_RS20550	COG0470	DNA polymerase III
BS11774_RS20550	COG1067	ATP-dependent peptidase activity
BS11774_RS20555	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BS11774_RS20560	COG0544	peptidyl-prolyl cis-trans isomerase activity
BS11774_RS20565	COG0457	Tetratricopeptide repeat
BS11774_RS20565	COG1477	protein flavinylation
BS11774_RS20570	COG0066	3-isopropylmalate dehydratase activity
BS11774_RS20575	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BS11774_RS20580	COG0473	3-isopropylmalate dehydrogenase activity
BS11774_RS20585	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BS11774_RS20590	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BS11774_RS20595	COG0440	acetolactate synthase activity
BS11774_RS20600	COG0028	Belongs to the TPP enzyme family
BS11774_RS20615	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
BS11774_RS20625	COG0622	Phosphoesterase
BS11774_RS20630	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BS11774_RS20635	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BS11774_RS20640	COG5401	PFAM Sporulation and spore germination
BS11774_RS20645	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BS11774_RS20650	COG1846	Transcriptional regulator
BS11774_RS20655	COG2197	response regulator
BS11774_RS20660	COG0824	Thioesterase
BS11774_RS20665	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BS11774_RS20670	COG1053	succinate dehydrogenase
BS11774_RS20675	COG2009	succinate dehydrogenase
BS11774_RS20680	COG1719	4-vinyl reductase, 4VR
BS11774_RS20685	COG0527	aspartate kinase activity
BS11774_RS20695	COG0322	excinuclease ABC activity
BS11774_RS20700	COG3118	belongs to the thioredoxin family
BS11774_RS20710	COG3534	alpha-L-arabinofuranosidase
BS11774_RS20715	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BS11774_RS20720	COG2086	electron transfer activity
BS11774_RS20725	COG1024	Enoyl-CoA hydratase
BS11774_RS20730	COG1309	transcriptional regulator
BS11774_RS20735	COG0318	PFAM AMP-dependent synthetase and ligase
BS11774_RS20740	COG3766	membrane
BS11774_RS20745	COG1193	negative regulation of DNA recombination
BS11774_RS20750	COG1796	DNA polymerase
BS11774_RS20750	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BS11774_RS20755	COG1286	toxin biosynthetic process
BS11774_RS20760	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BS11774_RS20765	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BS11774_RS20770	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BS11774_RS20770	COG0072	phenylalanine-tRNA ligase activity
BS11774_RS20775	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BS11774_RS20785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BS11774_RS20795	COG3835	regulator
BS11774_RS20800	COG0277	FAD linked oxidase domain protein
BS11774_RS20805	COG0247	lactate metabolic process
BS11774_RS20810	COG0346	lactoylglutathione lyase activity
BS11774_RS20820	COG1966	Carbon starvation protein
BS11774_RS20825	COG3534	alpha-L-arabinofuranosidase
BS11774_RS20830	COG0395	ABC-type sugar transport system, permease component
BS11774_RS20835	COG1175	transmembrane transport
BS11774_RS20840	COG1653	transport
BS11774_RS20845	COG0371	Dehydrogenase
BS11774_RS20850	COG0647	UMP catabolic process
BS11774_RS20855	COG0235	Class ii aldolase
BS11774_RS20860	COG1069	ribulokinase activity
BS11774_RS20865	COG2160	L-arabinose isomerase activity
BS11774_RS20875	COG3507	Belongs to the glycosyl hydrolase 43 family
BS11774_RS20880	COG1363	Peptidase, m42
BS11774_RS20890	COG3326	Membrane
BS11774_RS20895	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BS11774_RS20900	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BS11774_RS20905	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BS11774_RS20915	COG1346	cytolysis
BS11774_RS20920	COG1380	Effector of murein hydrolase LrgA
BS11774_RS20925	COG3279	Response regulator of the LytR AlgR family
BS11774_RS20930	COG3275	phosphorelay sensor kinase activity
BS11774_RS20935	COG1011	Hydrolase
BS11774_RS20940	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BS11774_RS20950	COG0398	Pfam SNARE associated Golgi protein
BS11774_RS20955	COG1484	DNA-dependent DNA replication
BS11774_RS20960	COG3611	Membrane attachment protein
BS11774_RS20965	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BS11774_RS20970	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BS11774_RS20975	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BS11774_RS20980	COG1733	regulation of RNA biosynthetic process
BS11774_RS20985	COG2814	Major facilitator Superfamily
BS11774_RS20990	COG0656	L-ascorbic acid biosynthetic process
BS11774_RS20995	COG0237	dephospho-CoA kinase activity
BS11774_RS21000	COG1971	Probably functions as a manganese efflux pump
BS11774_RS21005	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BS11774_RS21010	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BS11774_RS21010	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BS11774_RS21015	COG5002	protein histidine kinase activity
BS11774_RS21020	COG0745	RESPONSE REGULATOR receiver
BS11774_RS21025	COG0039	L-malate dehydrogenase activity
BS11774_RS21030	COG0538	isocitrate dehydrogenase activity
BS11774_RS21035	COG0372	Belongs to the citrate synthase family
BS11774_RS21040	COG2707	UPF0756 membrane protein
BS11774_RS21045	COG0628	permease
BS11774_RS21050	COG3030	protein affecting phage T7 exclusion by the F plasmid
BS11774_RS21055	COG0469	pyruvate kinase activity
BS11774_RS21060	COG0205	6-phosphofructokinase activity
BS11774_RS21065	COG0825	malonyl-CoA metabolic process
BS11774_RS21070	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BS11774_RS21075	COG0281	malic enzyme
BS11774_RS21080	COG0587	DNA-directed DNA polymerase activity
BS11774_RS21100	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BS11774_RS21110	COG4109	DRTGG domain
BS11774_RS21115	COG0730	response to heat
BS11774_RS21120	COG1473	amidohydrolase
BS11774_RS21125	COG0196	riboflavin kinase activity
BS11774_RS21130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BS11774_RS21135	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BS11774_RS21140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BS11774_RS21145	COG1126	abc transporter atp-binding protein
BS11774_RS21150	COG0765	amino acid transport
BS11774_RS21155	COG0765	amino acid transport
BS11774_RS21160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BS11774_RS21165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BS11774_RS21170	COG0454	-acetyltransferase
BS11774_RS21175	COG0583	DNA-binding transcription factor activity
BS11774_RS21180	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BS11774_RS21185	COG1028	Short-chain dehydrogenase reductase Sdr
BS11774_RS21195	COG0165	Argininosuccinate lyase
BS11774_RS21200	COG0137	argininosuccinate synthase activity
BS11774_RS21205	COG0521	Mo-molybdopterin cofactor biosynthetic process
BS11774_RS21210	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BS11774_RS21220	COG0827	DNA restriction-modification system
BS11774_RS21225	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BS11774_RS21230	COG3874	Sporulation protein YtfJ
BS11774_RS21240	COG1714	RDD family
BS11774_RS21245	COG0616	signal peptide processing
BS11774_RS21250	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BS11774_RS21255	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BS11774_RS21260	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BS11774_RS21270	COG0301	tRNA thio-modification
BS11774_RS21275	COG1104	cysteine desulfurase activity
BS11774_RS21280	COG1114	Component of the transport system for branched-chain amino acids
BS11774_RS21285	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BS11774_RS21290	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BS11774_RS21295	COG1309	transcriptional regulator
BS11774_RS21300	COG1956	GAF domain-containing protein
BS11774_RS21320	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BS11774_RS21325	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BS11774_RS21330	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BS11774_RS21335	COG0454	-acetyltransferase
BS11774_RS21340	COG0517	IMP dehydrogenase activity
BS11774_RS21345	COG0123	including yeast histone deacetylase and acetoin utilization protein
BS11774_RS21350	COG1360	Flagellar Motor Protein
BS11774_RS21355	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BS11774_RS21360	COG1609	Transcriptional regulator
BS11774_RS21365	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BS11774_RS21365	COG1605	Chorismate mutase
BS11774_RS21370	COG3118	belongs to the thioredoxin family
BS11774_RS21375	COG4980	gas vesicle protein
BS11774_RS21380	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BS11774_RS21385	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BS11774_RS21390	COG1674	ftsk spoiiie
BS11774_RS21395	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BS11774_RS21400	COG4848	Belongs to the UPF0354 family
BS11774_RS21405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS11774_RS21420	COG1363	Peptidase, m42
BS11774_RS21425	COG5584	Small secreted protein
BS11774_RS21430	COG0281	malic enzyme
BS11774_RS21435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BS11774_RS21440	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BS11774_RS21450	COG0510	thiamine kinase activity
BS11774_RS21455	COG1523	belongs to the glycosyl hydrolase 13 family
BS11774_RS21460	COG1597	lipid kinase activity
BS11774_RS21470	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BS11774_RS21475	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BS11774_RS21480	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BS11774_RS21485	COG2252	PERMEase
BS11774_RS21490	COG4473	ABC transporter
BS11774_RS21500	COG1349	DNA-binding transcription factor activity
BS11774_RS21505	COG1187	pseudouridine synthase activity
BS11774_RS21510	COG2244	polysaccharide biosynthetic process
BS11774_RS21515	COG2081	HI0933 family
BS11774_RS21520	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BS11774_RS21530	COG5578	integral membrane protein
BS11774_RS21535	COG0673	inositol 2-dehydrogenase activity
BS11774_RS21540	COG1653	transport
BS11774_RS21545	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BS11774_RS21550	COG4209	transmembrane transport
BS11774_RS21555	COG2207	Transcriptional regulator
BS11774_RS21560	COG1653	transport
BS11774_RS21565	COG0395	ABC-type sugar transport system, permease component
BS11774_RS21570	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BS11774_RS21575	COG2124	cytochrome p450
BS11774_RS21580	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BS11774_RS21590	COG0156	8-amino-7-oxononanoate synthase activity
BS11774_RS21595	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BS11774_RS21610	COG1073	alpha beta
BS11774_RS21615	COG1609	Transcriptional regulator
BS11774_RS21620	COG1653	transport
BS11774_RS21625	COG1175	transmembrane transport
BS11774_RS21630	COG0395	ABC-type sugar transport system, permease component
BS11774_RS21635	COG1486	melibiose metabolic process
BS11774_RS21640	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BS11774_RS21645	COG0495	leucyl-tRNA aminoacylation
BS11774_RS21655	COG1366	Belongs to the anti-sigma-factor antagonist family
BS11774_RS21655	COG2202	Pas domain
BS11774_RS21665	COG2814	Major facilitator Superfamily
BS11774_RS21670	COG2433	Pfam Transposase IS66
BS11774_RS21675	COG0577	efflux transmembrane transporter activity
BS11774_RS21680	COG1136	(ABC) transporter
BS11774_RS21685	COG2205	protein histidine kinase activity
BS11774_RS21690	COG0745	RESPONSE REGULATOR receiver
BS11774_RS21695	COG0577	efflux transmembrane transporter activity
BS11774_RS21700	COG1136	(ABC) transporter
BS11774_RS21715	COG1131	(ABC) transporter
BS11774_RS21720	COG1725	Transcriptional regulator
BS11774_RS21735	COG1242	4 iron, 4 sulfur cluster binding
BS11774_RS21740	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BS11774_RS21750	COG2267	carboxylic ester hydrolase activity
BS11774_RS21755	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BS11774_RS21760	COG1113	amino acid transport
BS11774_RS21765	COG0367	asparagine synthase
BS11774_RS21770	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BS11774_RS21775	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BS11774_RS21785	COG1506	peptidase
BS11774_RS21790	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BS11774_RS21795	COG1116	anion transmembrane transporter activity
BS11774_RS21800	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BS11774_RS21805	COG0494	nUDIX hydrolase
BS11774_RS21810	COG4824	toxin secretion phage lysis holin
BS11774_RS21815	COG0783	Belongs to the Dps family
BS11774_RS21830	COG1854	S-ribosylhomocysteine lyase activity
BS11774_RS21835	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BS11774_RS21840	COG0288	reversible hydration of carbon dioxide
BS11774_RS21845	COG0254	rRNA binding
BS11774_RS21850	COG1271	oxidase subunit
BS11774_RS21855	COG1294	oxidase, subunit
BS11774_RS21865	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BS11774_RS21870	COG1321	iron dependent repressor
BS11774_RS21870	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BS11774_RS21875	COG1121	(ABC) transporter
BS11774_RS21880	COG0803	Belongs to the bacterial solute-binding protein 9 family
BS11774_RS21885	COG4948	Mandelate Racemase Muconate Lactonizing
BS11774_RS21890	COG0318	PFAM AMP-dependent synthetase and ligase
BS11774_RS21895	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BS11774_RS21900	COG0596	Alpha beta hydrolase
BS11774_RS21905	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BS11774_RS21910	COG1169	isochorismate synthase
BS11774_RS21920	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BS11774_RS21925	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BS11774_RS21930	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BS11774_RS21935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BS11774_RS21940	COG0438	transferase activity, transferring glycosyl groups
BS11774_RS21950	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BS11774_RS21955	COG0438	transferase activity, transferring glycosyl groups
BS11774_RS21960	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BS11774_RS21965	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)