locus-tag	class	description
KS08_RS00010	COG0592	DNA-directed DNA polymerase activity
KS08_RS00015	COG2501	S4 domain
KS08_RS00030	COG0187	DNA topoisomerase II activity
KS08_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KS08_RS00070	COG0516	GMP reductase activity
KS08_RS00070	COG0517	IMP dehydrogenase activity
KS08_RS00075	COG1686	Belongs to the peptidase S11 family
KS08_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
KS08_RS00105	COG1428	Deoxynucleoside kinase
KS08_RS00110	COG1428	Deoxynucleoside kinase
KS08_RS00115	COG3858	chitin binding
KS08_RS00115	COG1388	LysM domain
KS08_RS00120	COG1335	isochorismatase
KS08_RS00125	COG0590	tRNA wobble adenosine to inosine editing
KS08_RS00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KS08_RS00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KS08_RS00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
KS08_RS00190	COG3853	Toxic anion resistance protein (TelA)
KS08_RS00195	COG1982	Orn Lys Arg decarboxylase major
KS08_RS00205	COG3870	Protein conserved in bacteria
KS08_RS00210	COG1728	Protein conserved in bacteria
KS08_RS00215	COG0470	DNA polymerase III
KS08_RS00220	COG1774	PSP1 C-terminal conserved region
KS08_RS00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KS08_RS00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KS08_RS00245	COG2002	toxin-antitoxin pair type II binding
KS08_RS00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KS08_RS00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KS08_RS00255	COG0084	hydrolase, TatD family'
KS08_RS00260	COG3584	3D domain protein
KS08_RS00260	COG3583	domain protein
KS08_RS00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KS08_RS00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KS08_RS00280	COG4466	Protein conserved in bacteria
KS08_RS00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KS08_RS00300	COG0251	oxidation-reduction process
KS08_RS00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KS08_RS00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KS08_RS00340	COG2002	toxin-antitoxin pair type II binding
KS08_RS00345	COG2244	polysaccharide biosynthetic process
KS08_RS00350	COG3956	TIGRFAM MazG family protein
KS08_RS00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KS08_RS00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KS08_RS00375	COG1098	S1 RNA binding domain
KS08_RS00390	COG2208	phosphoserine phosphatase activity
KS08_RS00395	COG2304	oxidoreductase activity
KS08_RS00400	COG0515	serine threonine protein kinase
KS08_RS00405	COG0037	tRNA processing
KS08_RS00410	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KS08_RS00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KS08_RS00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KS08_RS00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KS08_RS00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KS08_RS00445	COG0512	Glutamine amidotransferase of anthranilate synthase
KS08_RS00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KS08_RS00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KS08_RS00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KS08_RS00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KS08_RS00470	COG1396	sequence-specific DNA binding
KS08_RS00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KS08_RS00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KS08_RS00500	COG4463	regulation of RNA biosynthetic process
KS08_RS00505	COG3880	PFAM UvrB UvrC protein
KS08_RS00515	COG0542	response to heat
KS08_RS00520	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KS08_RS00525	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
KS08_RS00530	COG4956	integral membrane protein (PIN domain superfamily)
KS08_RS00550	COG1045	serine acetyltransferase
KS08_RS00560	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KS08_RS00565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KS08_RS00570	COG3688	RNA-binding protein containing a PIN domain
KS08_RS00575	COG1595	DNA-templated transcription, initiation
KS08_RS00585	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KS08_RS00590	COG0250	Participates in transcription elongation, termination and antitermination
KS08_RS00615	COG2813	Specifically methylates the guanine in position
KS08_RS00630	COG1358	cellular component organization or biogenesis
KS08_RS00655	COG0596	Alpha beta hydrolase
KS08_RS00760	COG0201	protein transport
KS08_RS00770	COG0024	Methionine aminopeptidase
KS08_RS00780	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KS08_RS00805	COG1122	ATPase activity
KS08_RS00810	COG1122	ATPase activity
KS08_RS00815	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KS08_RS00825	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KS08_RS00835	COG2226	methyltransferase
KS08_RS00845	COG0860	N-Acetylmuramoyl-L-alanine amidase
KS08_RS00850	COG0489	protein tyrosine kinase activity
KS08_RS00860	COG2194	sulfuric ester hydrolase activity
KS08_RS00865	COG0726	polysaccharide deacetylase
KS08_RS00885	COG0738	Major facilitator superfamily
KS08_RS00890	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KS08_RS00905	COG0659	secondary active sulfate transmembrane transporter activity
KS08_RS00910	COG0385	Bile acid
KS08_RS00915	COG2819	hydrolase of the alpha beta superfamily
KS08_RS00920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KS08_RS00925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KS08_RS00930	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KS08_RS00935	COG2207	Transcriptional regulator
KS08_RS00935	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KS08_RS00940	COG3876	Protein conserved in bacteria
KS08_RS00945	COG1472	Belongs to the glycosyl hydrolase 3 family
KS08_RS00950	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KS08_RS00955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KS08_RS00955	COG1263	PTS System
KS08_RS00965	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KS08_RS00970	COG1683	Conserved Protein
KS08_RS01000	COG1595	DNA-templated transcription, initiation
KS08_RS01005	COG5662	AntiSigma factor
KS08_RS01010	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KS08_RS01015	COG4856	YbbR-like protein
KS08_RS01060	COG1346	cytolysis
KS08_RS01065	COG1380	Effector of murein hydrolase LrgA
KS08_RS01070	COG1846	Transcriptional regulator
KS08_RS01075	COG1113	amino acid transport
KS08_RS01080	COG1011	Hydrolase
KS08_RS01085	COG4585	Histidine kinase
KS08_RS01090	COG2197	response regulator
KS08_RS01095	COG1131	(ABC) transporter
KS08_RS01105	COG0842	Transport permease protein
KS08_RS01105	COG1511	domain protein
KS08_RS01135	COG0531	amino acid
KS08_RS01145	COG0584	glycerophosphoryl diester phosphodiesterase
KS08_RS01150	COG2271	Major facilitator Superfamily
KS08_RS01160	COG2368	4-hydroxyphenylacetate
KS08_RS01175	COG0371	Dehydrogenase
KS08_RS01185	COG1183	phosphatidylcholine synthase activity
KS08_RS01190	COG0586	Pfam SNARE associated Golgi protein
KS08_RS01195	COG0688	phosphatidylethanolamine metabolic process
KS08_RS01210	COG1301	dicarboxylic acid transport
KS08_RS01215	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KS08_RS01220	COG0833	amino acid
KS08_RS01225	COG2040	homocysteine
KS08_RS01230	COG1115	amino acid carrier protein
KS08_RS01235	COG2066	Belongs to the glutaminase family
KS08_RS01240	COG4191	Histidine kinase
KS08_RS01245	COG0784	Response regulator, receiver
KS08_RS01250	COG3173	Aminoglycoside phosphotransferase
KS08_RS01265	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KS08_RS01270	COG0778	Nitroreductase
KS08_RS01275	COG0346	lactoylglutathione lyase activity
KS08_RS01280	COG2259	Doxx family
KS08_RS01285	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KS08_RS01300	COG3773	Cell wall hydrolase
KS08_RS01305	COG3540	Alkaline phosphatase
KS08_RS01310	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KS08_RS01315	COG0805	protein transport
KS08_RS01320	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KS08_RS01325	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KS08_RS01330	COG0477	Major facilitator Superfamily
KS08_RS01335	COG1309	transcriptional regulator
KS08_RS01340	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KS08_RS01345	COG1405	negative regulation of cell septum assembly
KS08_RS01345	COG3012	SEC-C Motif Domain Protein
KS08_RS01350	COG0667	Aldo Keto reductase
KS08_RS01360	COG1595	DNA-templated transcription, initiation
KS08_RS01365	COG1595	DNA-templated transcription, initiation
KS08_RS01370	COG1876	peptidase activity
KS08_RS01375	COG0457	Tetratricopeptide repeat
KS08_RS01380	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_RS01385	COG0366	Alpha amylase catalytic
KS08_RS01395	COG1695	Transcriptional regulator
KS08_RS01400	COG0803	Belongs to the bacterial solute-binding protein 9 family
KS08_RS01405	COG1121	(ABC) transporter
KS08_RS01410	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KS08_RS01415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KS08_RS01420	COG2310	stress, protein
KS08_RS01425	COG2310	stress, protein
KS08_RS01430	COG2310	stress, protein
KS08_RS01435	COG0861	Integral membrane protein TerC family
KS08_RS01445	COG3853	Toxic anion resistance protein (TelA)
KS08_RS01450	COG0477	Major facilitator Superfamily
KS08_RS01455	COG4175	Glycine betaine
KS08_RS01455	COG0517	IMP dehydrogenase activity
KS08_RS01460	COG4176	ABC-type proline glycine betaine transport system permease component
KS08_RS01465	COG2113	Glycine betaine
KS08_RS01470	COG1473	amidohydrolase
KS08_RS01475	COG1288	antiporter activity
KS08_RS01485	COG1714	RDD family
KS08_RS01495	COG2814	Major facilitator Superfamily
KS08_RS01500	COG1846	Transcriptional regulator
KS08_RS01505	COG1280	lysine exporter protein (LysE YggA)
KS08_RS01510	COG3403	YqcI/YcgG family
KS08_RS01515	COG1113	amino acid transport
KS08_RS01520	COG3665	Urea carboxylase-associated protein
KS08_RS01530	COG1082	Xylose isomerase domain protein TIM barrel
KS08_RS01535	COG2271	Major facilitator Superfamily
KS08_RS01540	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KS08_RS01545	COG3458	cephalosporin-C deacetylase activity
KS08_RS01550	COG3541	Predicted nucleotidyltransferase
KS08_RS01555	COG0506	proline dehydrogenase activity
KS08_RS01560	COG1012	belongs to the aldehyde dehydrogenase family
KS08_RS01565	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KS08_RS01570	COG2508	Transcriptional regulator
KS08_RS01580	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KS08_RS01580	COG1587	Uroporphyrinogen-III synthase
KS08_RS01585	COG2146	nitrite reductase [NAD(P)H] activity
KS08_RS01590	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KS08_RS01595	COG2223	nitrite transmembrane transporter activity
KS08_RS01600	COG0523	cobalamin synthesis protein
KS08_RS01605	COG1063	alcohol dehydrogenase
KS08_RS01610	COG1714	RDD family
KS08_RS01620	COG2723	6-phospho-beta-galactosidase activity
KS08_RS01630	COG3209	COG3209 Rhs family protein
KS08_RS01635	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KS08_RS01640	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
KS08_RS01645	COG1733	regulation of RNA biosynthetic process
KS08_RS01655	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KS08_RS01660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KS08_RS01665	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KS08_RS01670	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
KS08_RS01685	COG2364	Membrane
KS08_RS01690	COG1126	abc transporter atp-binding protein
KS08_RS01695	COG0765	amino acid transport
KS08_RS01700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KS08_RS01705	COG0583	DNA-binding transcription factor activity
KS08_RS01710	COG0163	prenyltransferase activity
KS08_RS01715	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KS08_RS01730	COG3104	oligopeptide transport
KS08_RS01735	COG5434	Belongs to the glycosyl hydrolase 28 family
KS08_RS01745	COG0697	spore germination
KS08_RS01755	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KS08_RS01760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KS08_RS01765	COG0456	acetyltransferase
KS08_RS01770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KS08_RS01775	COG0765	amino acid transport
KS08_RS01780	COG1126	abc transporter atp-binding protein
KS08_RS01785	COG1473	amidohydrolase
KS08_RS01790	COG2079	MmgE PrpD family protein
KS08_RS01795	COG1136	(ABC) transporter
KS08_RS01800	COG0577	efflux transmembrane transporter activity
KS08_RS01805	COG0745	RESPONSE REGULATOR receiver
KS08_RS01810	COG3850	Histidine kinase
KS08_RS01810	COG5002	protein histidine kinase activity
KS08_RS01815	COG0457	Tetratricopeptide repeat
KS08_RS01830	COG0527	aspartate kinase activity
KS08_RS01835	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KS08_RS01840	COG4605	iron ion homeostasis
KS08_RS01845	COG4604	ABC transporter, ATP-binding protein
KS08_RS01850	COG4607	ABC-type enterochelin transport system periplasmic component
KS08_RS01855	COG2814	Major facilitator Superfamily
KS08_RS01860	COG1309	transcriptional regulator
KS08_RS01865	COG0778	Nitroreductase
KS08_RS01870	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KS08_RS01875	COG0640	Transcriptional regulator
KS08_RS01880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KS08_RS01885	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KS08_RS01890	COG1012	belongs to the aldehyde dehydrogenase family
KS08_RS01895	COG4975	Glucose uptake
KS08_RS01900	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_RS01905	COG4549	nuclear export factor GLE1
KS08_RS01910	COG1276	copper resistance
KS08_RS01910	COG2372	response to copper ion
KS08_RS01915	COG1349	DNA-binding transcription factor activity
KS08_RS01925	COG2213	PTS system mannitol-specific
KS08_RS01930	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KS08_RS01940	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KS08_RS01945	COG0561	phosphatase activity
KS08_RS01955	COG1914	H( )-stimulated, divalent metal cation uptake system
KS08_RS01965	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KS08_RS01970	COG1984	allophanate hydrolase subunit 2
KS08_RS01975	COG1414	Transcriptional regulator
KS08_RS01980	COG2755	lipolytic protein G-D-S-L family
KS08_RS01990	COG2329	Antibiotic biosynthesis monooxygenase
KS08_RS01995	COG0768	penicillin binding
KS08_RS02000	COG4989	oxidoreductase activity
KS08_RS02005	COG3711	transcriptional antiterminator
KS08_RS02010	COG0318	PFAM AMP-dependent synthetase and ligase
KS08_RS02015	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_RS02020	COG1917	Cupin 2, conserved barrel domain protein
KS08_RS02025	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KS08_RS02030	COG3871	stress protein (general stress protein 26)
KS08_RS02040	COG2814	Major facilitator Superfamily
KS08_RS02045	COG1522	sequence-specific DNA binding
KS08_RS02050	COG0551	DNA topoisomerase type I activity
KS08_RS02050	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KS08_RS02055	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KS08_RS02060	COG3706	GGDEF domain
KS08_RS02065	COG5298	Protein conserved in bacteria
KS08_RS02080	COG0531	amino acid
KS08_RS02085	COG0028	Belongs to the TPP enzyme family
KS08_RS02115	COG0457	Tetratricopeptide repeat
KS08_RS02130	COG1914	H( )-stimulated, divalent metal cation uptake system
KS08_RS02145	COG4876	unkown
KS08_RS02155	COG2076	Multidrug Resistance protein
KS08_RS02160	COG2217	Heavy metal translocating P-type atpase
KS08_RS02165	COG3729	General stress protein
KS08_RS02170	COG0662	Cupin 2, conserved barrel domain protein
KS08_RS02175	COG2329	Antibiotic biosynthesis monooxygenase
KS08_RS02180	COG3546	catalase activity
KS08_RS02185	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KS08_RS02190	COG3290	protein histidine kinase activity
KS08_RS02195	COG4565	transcriptional regulatory protein
KS08_RS02200	COG1301	dicarboxylic acid transport
KS08_RS02205	COG0628	permease
KS08_RS02210	COG1131	(ABC) transporter
KS08_RS02215	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KS08_RS02225	COG1960	acyl-CoA dehydrogenase activity
KS08_RS02235	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KS08_RS02240	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KS08_RS02250	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KS08_RS02255	COG0513	Belongs to the DEAD box helicase family
KS08_RS02260	COG3402	PFAM membrane-flanked domain
KS08_RS02265	COG3428	Bacterial PH domain
KS08_RS02270	COG0705	Rhomboid family
KS08_RS02280	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KS08_RS02285	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KS08_RS02290	COG0864	Transcriptional regulator
KS08_RS02295	COG2337	Toxic component of a toxin-antitoxin (TA) module
KS08_RS02300	COG1366	Belongs to the anti-sigma-factor antagonist family
KS08_RS02305	COG1366	Belongs to the anti-sigma-factor antagonist family
KS08_RS02310	COG2172	sigma factor antagonist activity
KS08_RS02315	COG2208	phosphoserine phosphatase activity
KS08_RS02320	COG1366	Belongs to the anti-sigma-factor antagonist family
KS08_RS02330	COG1191	sigma factor activity
KS08_RS02335	COG2208	phosphoserine phosphatase activity
KS08_RS02340	COG2183	response to ionizing radiation
KS08_RS02390	COG1764	response to oxidative stress
KS08_RS02395	COG1846	Transcriptional regulator
KS08_RS02405	COG1846	Transcriptional regulator
KS08_RS02405	COG0456	acetyltransferase
KS08_RS02410	COG2271	Major facilitator Superfamily
KS08_RS02415	COG4124	Belongs to the glycosyl hydrolase 26 family
KS08_RS02435	COG1959	2 iron, 2 sulfur cluster binding
KS08_RS02445	COG1278	Cold shock
KS08_RS02450	COG1794	racemase activity, acting on amino acids and derivatives
KS08_RS02465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KS08_RS02470	COG0477	Major facilitator Superfamily
KS08_RS02475	COG3621	Patatin-like phospholipase
KS08_RS02485	COG0277	FAD linked oxidase domain protein
KS08_RS02505	COG0662	Cupin 2, conserved barrel domain protein
KS08_RS02510	COG0456	acetyltransferase
KS08_RS02515	COG3708	Transcriptional regulator
KS08_RS02515	COG2207	Transcriptional regulator
KS08_RS02540	COG1064	alcohol dehydrogenase
KS08_RS02545	COG0789	Transcriptional regulator
KS08_RS02555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KS08_RS02560	COG2808	Putative FMN-binding domain
KS08_RS02565	COG2814	Major facilitator Superfamily
KS08_RS02570	COG1309	transcriptional regulator
KS08_RS02575	COG0697	spore germination
KS08_RS02580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KS08_RS02585	COG5577	PFAM Coat F domain
KS08_RS02595	COG1063	alcohol dehydrogenase
KS08_RS02600	COG5577	PFAM Coat F domain
KS08_RS02610	COG2409	Drug exporters of the RND superfamily
KS08_RS02615	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KS08_RS02620	COG0488	(ABC) transporter
KS08_RS02625	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KS08_RS02630	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KS08_RS02640	COG2814	Major facilitator Superfamily
KS08_RS02645	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KS08_RS02655	COG0730	response to heat
KS08_RS02660	COG0456	acetyltransferase
KS08_RS02665	COG4978	Transcriptional regulator
KS08_RS02665	COG0789	Transcriptional regulator
KS08_RS02670	COG0697	spore germination
KS08_RS02675	COG1051	belongs to the nudix hydrolase family
KS08_RS02680	COG0596	Alpha beta hydrolase
KS08_RS02685	COG0473	3-isopropylmalate dehydrogenase activity
KS08_RS02690	COG1802	Transcriptional regulator
KS08_RS02695	COG1819	glycosyl
KS08_RS02705	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KS08_RS02710	COG1388	LysM domain
KS08_RS02715	COG2814	Major facilitator Superfamily
KS08_RS02720	COG2188	Transcriptional regulator
KS08_RS02725	COG2186	Transcriptional regulator
KS08_RS02730	COG2807	transmembrane transport
KS08_RS02735	COG2076	Multidrug Resistance protein
KS08_RS02740	COG2076	Multidrug Resistance protein
KS08_RS02745	COG1309	transcriptional regulator
KS08_RS02750	COG0531	amino acid
KS08_RS02760	COG3832	glyoxalase III activity
KS08_RS02765	COG0604	alcohol dehydrogenase
KS08_RS02770	COG2814	Major facilitator Superfamily
KS08_RS02810	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KS08_RS02815	COG0802	atpase or kinase
KS08_RS02820	COG1214	PFAM Peptidase M22, glycoprotease
KS08_RS02825	COG0456	acetyltransferase
KS08_RS02830	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KS08_RS02835	COG0488	(ABC) transporter
KS08_RS02850	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KS08_RS02855	COG0805	protein transport
KS08_RS02865	COG1266	CAAX protease self-immunity
KS08_RS02880	COG3409	Peptidoglycan-binding domain 1 protein
KS08_RS02895	COG0457	Tetratricopeptide repeat
KS08_RS02900	COG1063	alcohol dehydrogenase
KS08_RS02905	COG2211	Major facilitator Superfamily
KS08_RS02910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KS08_RS02920	COG1842	Phage shock protein A
KS08_RS02925	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KS08_RS02930	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
KS08_RS02935	COG4260	virion core protein, lumpy skin disease virus
KS08_RS02940	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KS08_RS02940	COG2755	lipolytic protein G-D-S-L family
KS08_RS02950	COG1595	DNA-templated transcription, initiation
KS08_RS02955	COG1063	alcohol dehydrogenase
KS08_RS02960	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KS08_RS02965	COG0823	Involved in the tonB-independent uptake of proteins
KS08_RS02980	COG2132	Multicopper oxidase
KS08_RS02985	COG1113	amino acid transport
KS08_RS02995	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KS08_RS03000	COG0714	Associated with various cellular activities
KS08_RS03005	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KS08_RS03010	COG1305	Transglutaminase-like
KS08_RS03030	COG2252	PERMEase
KS08_RS03035	COG3064	Membrane
KS08_RS03050	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KS08_RS03055	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KS08_RS03060	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KS08_RS03065	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KS08_RS03070	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KS08_RS03085	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KS08_RS03095	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KS08_RS03100	COG0138	bifunctional purine biosynthesis protein purh
KS08_RS03105	COG0151	Belongs to the GarS family
KS08_RS03110	COG1522	sequence-specific DNA binding
KS08_RS03115	COG0531	amino acid
KS08_RS03125	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KS08_RS03130	COG1470	cell adhesion involved in biofilm formation
KS08_RS03135	COG4496	protein, YerC YecD
KS08_RS03140	COG0069	glutamate synthase activity
KS08_RS03155	COG0210	DNA helicase
KS08_RS03165	COG4851	CamS sex pheromone cAM373 precursor
KS08_RS03170	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KS08_RS03175	COG1285	pathogenesis
KS08_RS03180	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KS08_RS03200	COG1309	transcriptional regulator
KS08_RS03205	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KS08_RS03210	COG1597	lipid kinase activity
KS08_RS03215	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KS08_RS03225	COG1131	(ABC) transporter
KS08_RS03250	COG5444	nuclease activity
KS08_RS03255	COG5444	nuclease activity
KS08_RS03285	COG3546	catalase activity
KS08_RS03290	COG0454	-acetyltransferase
KS08_RS03300	COG2323	membrane
KS08_RS03305	COG2329	Antibiotic biosynthesis monooxygenase
KS08_RS03310	COG0346	lactoylglutathione lyase activity
KS08_RS03315	COG1366	Belongs to the anti-sigma-factor antagonist family
KS08_RS03320	COG0196	riboflavin kinase activity
KS08_RS03325	COG0670	Belongs to the BI1 family
KS08_RS03330	COG1846	Transcriptional regulator
KS08_RS03335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KS08_RS03345	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KS08_RS03345	COG2124	cytochrome p450
KS08_RS03355	COG1368	sulfuric ester hydrolase activity
KS08_RS03360	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KS08_RS03365	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KS08_RS03370	COG1442	glycosyl transferase family 8
KS08_RS03375	COG1216	Glycosyl transferase, family 2
KS08_RS03380	COG1442	glycosyl transferase family 8
KS08_RS03385	COG2223	nitrite transmembrane transporter activity
KS08_RS03390	COG0531	amino acid
KS08_RS03395	COG1012	belongs to the aldehyde dehydrogenase family
KS08_RS03400	COG0840	transmembrane signaling receptor activity
KS08_RS03405	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_RS03410	COG0457	Tetratricopeptide repeat
KS08_RS03410	COG0463	Glycosyl transferase, family 2
KS08_RS03415	COG0488	(ABC) transporter
KS08_RS03420	COG0789	Transcriptional regulator
KS08_RS03425	COG2814	Major facilitator Superfamily
KS08_RS03430	COG0488	(ABC) transporter
KS08_RS03435	COG0513	Belongs to the DEAD box helicase family
KS08_RS03440	COG2130	NADP-dependent
KS08_RS03455	COG3866	Pectate lyase
KS08_RS03460	COG0471	metal ion transport
KS08_RS03480	COG2972	Histidine kinase
KS08_RS03480	COG0745	RESPONSE REGULATOR receiver
KS08_RS03495	COG3764	Sortase (surface protein transpeptidase)
KS08_RS03500	COG3290	protein histidine kinase activity
KS08_RS03505	COG4565	transcriptional regulatory protein
KS08_RS03510	COG3181	Tripartite tricarboxylate transporter family receptor
KS08_RS03515	COG2851	Citrate transporter
KS08_RS03520	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KS08_RS03525	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KS08_RS03535	COG2258	MOSC domain
KS08_RS03545	COG0024	Methionine aminopeptidase
KS08_RS03550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KS08_RS03550	COG1263	PTS System
KS08_RS03560	COG1368	sulfuric ester hydrolase activity
KS08_RS03570	COG0071	Belongs to the small heat shock protein (HSP20) family
KS08_RS03585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KS08_RS03585	COG1263	PTS System
KS08_RS03590	COG0366	Alpha amylase catalytic
KS08_RS03595	COG2188	Transcriptional regulator
KS08_RS03600	COG0778	Nitroreductase
KS08_RS03615	COG0737	Belongs to the 5'-nucleotidase family
KS08_RS03620	COG0693	protein deglycase activity
KS08_RS03625	COG1609	Transcriptional regulator
KS08_RS03640	COG2814	Major facilitator Superfamily
KS08_RS03650	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KS08_RS03655	COG4980	gas vesicle protein
KS08_RS03660	COG1295	ribonuclease BN
KS08_RS03665	COG0477	Major facilitator Superfamily
KS08_RS03670	COG0387	Pfam Sodium calcium exchanger
KS08_RS03680	COG0668	transmembrane transport
KS08_RS03685	COG0535	radical SAM domain protein
KS08_RS03695	COG0726	polysaccharide deacetylase
KS08_RS03700	COG2084	Dehydrogenase
KS08_RS03710	COG0598	Magnesium transport protein CorA
KS08_RS03715	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KS08_RS03720	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KS08_RS03735	COG1132	(ABC) transporter
KS08_RS03740	COG0515	serine threonine protein kinase
KS08_RS03750	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KS08_RS03755	COG4637	Psort location Cytoplasmic, score
KS08_RS03760	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KS08_RS03765	COG0022	dehydrogenase e1 component
KS08_RS03770	COG0508	dehydrogenase complex catalyzes the overall conversion of
KS08_RS03775	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KS08_RS03780	COG3284	Transcriptional regulator
KS08_RS03790	COG1486	melibiose metabolic process
KS08_RS03795	COG1737	Transcriptional regulator
KS08_RS03800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KS08_RS03800	COG1263	PTS System
KS08_RS03805	COG5434	Belongs to the glycosyl hydrolase 28 family
KS08_RS03810	COG1132	(ABC) transporter
KS08_RS03815	COG1132	(ABC) transporter
KS08_RS03820	COG2259	Doxx family
KS08_RS03825	COG2514	catechol 2,3-dioxygenase activity
KS08_RS03835	COG1695	Transcriptional regulator
KS08_RS03840	COG2249	NAD(P)H dehydrogenase (quinone) activity
KS08_RS03845	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
KS08_RS03850	COG2732	(Barnase) inhibitor
KS08_RS03855	COG2318	DinB family
KS08_RS03860	COG2814	Major facilitator Superfamily
KS08_RS03865	COG1846	Transcriptional regulator
KS08_RS03870	COG0392	lysyltransferase activity
KS08_RS03870	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KS08_RS03875	COG0384	phenazine biosynthesis protein PhzF
KS08_RS03880	COG0778	Nitroreductase
KS08_RS03890	COG1090	epimerase
KS08_RS03905	COG2814	Major facilitator Superfamily
KS08_RS03915	COG3591	Belongs to the peptidase S1B family
KS08_RS03930	COG3103	Sh3 type 3 domain protein
KS08_RS03935	COG5658	integral membrane protein
KS08_RS03940	COG0596	Alpha beta hydrolase
KS08_RS03945	COG0463	Glycosyl transferase, family 2
KS08_RS03950	COG4485	Bacterial membrane protein, YfhO
KS08_RS03955	COG1988	membrane-bound metal-dependent
KS08_RS03960	COG1194	a g-specific adenine glycosylase
KS08_RS03970	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_RS03990	COG1132	(ABC) transporter
KS08_RS03995	COG4129	membrane
KS08_RS04005	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KS08_RS04010	COG0735	belongs to the Fur family
KS08_RS04120	COG1757	Na H antiporter
KS08_RS04125	COG3340	Belongs to the peptidase S51 family
KS08_RS04135	COG0277	FAD linked oxidase domain protein
KS08_RS04145	COG0747	negative chemotaxis
KS08_RS04150	COG0601	transmembrane transport
KS08_RS04155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KS08_RS04160	COG0444	Belongs to the ABC transporter superfamily
KS08_RS04170	COG0753	catalase activity
KS08_RS04180	COG1116	anion transmembrane transporter activity
KS08_RS04185	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KS08_RS04190	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KS08_RS04220	COG1476	TRANSCRIPTIONal
KS08_RS04230	COG3382	B3 4 domain protein
KS08_RS04235	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KS08_RS04245	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KS08_RS04250	COG0789	Transcriptional regulator
KS08_RS04255	COG1664	Polymer-forming cytoskeletal
KS08_RS04260	COG1664	Polymer-forming cytoskeletal
KS08_RS04265	COG2766	serine protein kinase
KS08_RS04275	COG1846	Transcriptional regulator
KS08_RS04280	COG1566	PFAM secretion protein HlyD family protein
KS08_RS04285	COG2814	Major facilitator Superfamily
KS08_RS04290	COG0655	NAD(P)H dehydrogenase (quinone) activity
KS08_RS04305	COG1725	Transcriptional regulator
KS08_RS04310	COG1131	(ABC) transporter
KS08_RS04315	COG1131	(ABC) transporter
KS08_RS04320	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KS08_RS04325	COG1278	Cold shock
KS08_RS04330	COG1464	Belongs to the NlpA lipoprotein family
KS08_RS04335	COG3706	GGDEF domain
KS08_RS04340	COG1823	symporter activity
KS08_RS04345	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KS08_RS04365	COG5577	PFAM Coat F domain
KS08_RS04370	COG0737	Belongs to the 5'-nucleotidase family
KS08_RS04370	COG1525	nuclease
KS08_RS04370	COG4085	toxin activity
KS08_RS04375	COG3764	Sortase (surface protein transpeptidase)
KS08_RS04380	COG0564	pseudouridine synthase activity
KS08_RS04390	COG0517	IMP dehydrogenase activity
KS08_RS04395	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KS08_RS04400	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KS08_RS04400	COG3153	acetyltransferase
KS08_RS04405	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KS08_RS04410	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KS08_RS04415	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KS08_RS04425	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KS08_RS04430	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KS08_RS04435	COG2203	Gaf domain
KS08_RS04435	COG4585	Histidine kinase
KS08_RS04440	COG2197	response regulator
KS08_RS04445	COG0431	NADPH-dependent FMN reductase
KS08_RS04460	COG1388	LysM domain
KS08_RS04460	COG0791	NLP P60 protein
KS08_RS04465	COG1959	2 iron, 2 sulfur cluster binding
KS08_RS04470	COG0668	transmembrane transport
KS08_RS04475	COG2719	SpoVR family
KS08_RS04480	COG1785	Belongs to the alkaline phosphatase family
KS08_RS04485	COG1388	LysM domain
KS08_RS04485	COG0791	NLP P60 protein
KS08_RS04490	COG0583	DNA-binding transcription factor activity
KS08_RS04495	COG0372	Belongs to the citrate synthase family
KS08_RS04500	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_RS04505	COG0531	amino acid
KS08_RS04510	COG0733	neurotransmitter:sodium symporter activity
KS08_RS04525	COG1595	DNA-templated transcription, initiation
KS08_RS04530	COG0204	Acyl-transferase
KS08_RS04535	COG1253	flavin adenine dinucleotide binding
KS08_RS04540	COG0789	Transcriptional regulator
KS08_RS04545	COG0436	Aminotransferase
KS08_RS04550	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KS08_RS04555	COG1253	flavin adenine dinucleotide binding
KS08_RS04560	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KS08_RS04565	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KS08_RS04570	COG0584	glycerophosphoryl diester phosphodiesterase
KS08_RS04575	COG0668	transmembrane transport
KS08_RS04580	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KS08_RS04585	COG0726	polysaccharide deacetylase
KS08_RS04590	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KS08_RS04595	COG3226	Transcriptional regulator
KS08_RS04605	COG0589	response to stress
KS08_RS04610	COG1132	(ABC) transporter
KS08_RS04615	COG1132	(ABC) transporter
KS08_RS04620	COG0702	epimerase
KS08_RS04640	COG0189	ligase activity
KS08_RS04645	COG0189	ligase activity
KS08_RS04660	COG0561	phosphatase activity
KS08_RS04665	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KS08_RS04675	COG0475	glutathione-regulated potassium exporter activity
KS08_RS04680	COG0490	domain, Protein
KS08_RS04690	COG1024	Enoyl-CoA hydratase
KS08_RS04700	COG4152	abc transporter atp-binding protein
KS08_RS04705	COG1668	transmembrane transport
KS08_RS04710	COG0420	3'-5' exonuclease activity
KS08_RS04715	COG4717	serine-type aminopeptidase activity
KS08_RS04730	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KS08_RS04765	COG4980	gas vesicle protein
KS08_RS04780	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KS08_RS04785	COG0537	adenosine 5'-monophosphoramidase activity
KS08_RS04790	COG1131	(ABC) transporter
KS08_RS04795	COG4473	ABC transporter
KS08_RS04805	COG1473	amidohydrolase
KS08_RS04810	COG3069	C4-dicarboxylate transmembrane transporter activity
KS08_RS04815	COG2329	Antibiotic biosynthesis monooxygenase
KS08_RS04820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KS08_RS04830	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KS08_RS04835	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KS08_RS04840	COG1309	transcriptional regulator
KS08_RS04845	COG1511	domain protein
KS08_RS04850	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KS08_RS04860	COG1363	Peptidase, m42
KS08_RS04865	COG1301	dicarboxylic acid transport
KS08_RS04870	COG1234	tRNA 3'-trailer cleavage
KS08_RS04875	COG0095	Lipoate-protein ligase
KS08_RS04880	COG0702	epimerase
KS08_RS04885	COG0318	PFAM AMP-dependent synthetase and ligase
KS08_RS04895	COG0501	Belongs to the peptidase M48B family
KS08_RS04900	COG1404	Belongs to the peptidase S8 family
KS08_RS04905	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KS08_RS04910	COG0406	alpha-ribazole phosphatase activity
KS08_RS04915	COG0183	Belongs to the thiolase family
KS08_RS04920	COG0318	PFAM AMP-dependent synthetase and ligase
KS08_RS04925	COG1268	BioY protein
KS08_RS04930	COG0840	transmembrane signaling receptor activity
KS08_RS04935	COG0723	plastoquinol--plastocyanin reductase activity
KS08_RS04935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KS08_RS04940	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_RS04950	COG4903	ComK protein
KS08_RS04955	COG5646	InterPro IPR014922
KS08_RS04980	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KS08_RS04995	COG0398	Pfam SNARE associated Golgi protein
KS08_RS05000	COG0681	Belongs to the peptidase S26 family
KS08_RS05005	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KS08_RS05010	COG1846	Transcriptional regulator
KS08_RS05015	COG3180	Ammonia monooxygenase
KS08_RS05020	COG2814	Major facilitator Superfamily
KS08_RS05030	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KS08_RS05035	COG2323	membrane
KS08_RS05050	COG0420	3'-5' exonuclease activity
KS08_RS05055	COG0419	ATPase involved in DNA repair
KS08_RS05060	COG1403	HNH endonuclease
KS08_RS05100	COG0179	Fumarylacetoacetate (FAA) hydrolase
KS08_RS05110	COG1404	Belongs to the peptidase S8 family
KS08_RS05120	COG0367	asparagine synthase
KS08_RS05125	COG1562	ergosterol biosynthetic process
KS08_RS05130	COG0534	Mate efflux family protein
KS08_RS05135	COG2207	Transcriptional regulator
KS08_RS05135	COG1917	Cupin 2, conserved barrel domain protein
KS08_RS05140	COG1609	Transcriptional regulator
KS08_RS05145	COG0673	inositol 2-dehydrogenase activity
KS08_RS05150	COG2318	DinB family
KS08_RS05155	COG1279	arginine transmembrane transporter activity
KS08_RS05160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KS08_RS05165	COG1357	PFAM Pentapeptide repeats (8 copies)
KS08_RS05170	COG2153	protein acetylation
KS08_RS05175	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KS08_RS05175	COG0646	methionine synthase
KS08_RS05185	COG2996	Protein conserved in bacteria
KS08_RS05190	COG1744	ABC transporter substrate-binding protein PnrA-like
KS08_RS05195	COG0840	transmembrane signaling receptor activity
KS08_RS05200	COG2124	cytochrome p450
KS08_RS05205	COG1307	EDD domain protein, DegV family
KS08_RS05210	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KS08_RS05225	COG0561	phosphatase activity
KS08_RS05230	COG1073	alpha beta
KS08_RS05235	COG2151	metal-sulfur cluster biosynthetic enzyme
KS08_RS05245	COG0277	FAD linked oxidase domain protein
KS08_RS05250	COG2271	Major facilitator Superfamily
KS08_RS05260	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KS08_RS05270	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KS08_RS05275	COG0505	Belongs to the CarA family
KS08_RS05280	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KS08_RS05285	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KS08_RS05300	COG2267	carboxylic ester hydrolase activity
KS08_RS05310	COG1744	ABC transporter substrate-binding protein PnrA-like
KS08_RS05325	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KS08_RS05330	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KS08_RS05335	COG5504	Zn-dependent protease
KS08_RS05340	COG0444	Belongs to the ABC transporter superfamily
KS08_RS05345	COG4608	Belongs to the ABC transporter superfamily
KS08_RS05355	COG0601	transmembrane transport
KS08_RS05360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KS08_RS05370	COG0180	Tryptophanyl-tRNA synthetase
KS08_RS05375	COG4166	transmembrane transport
KS08_RS05380	COG0601	transmembrane transport
KS08_RS05385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KS08_RS05390	COG0444	Belongs to the ABC transporter superfamily
KS08_RS05395	COG4608	Belongs to the ABC transporter superfamily
KS08_RS05405	COG0456	acetyltransferase
KS08_RS05410	COG1393	Belongs to the ArsC family
KS08_RS05415	COG0861	Integral membrane protein TerC family
KS08_RS05420	COG4862	establishment of competence for transformation
KS08_RS05425	COG4469	Competence protein
KS08_RS05430	COG1164	Oligoendopeptidase f
KS08_RS05440	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KS08_RS05445	COG2346	COG2346, Truncated hemoglobins
KS08_RS05450	COG0741	lytic transglycosylase activity
KS08_RS05455	COG4116	CYTH
KS08_RS05465	COG2357	RelA SpoT domain protein
KS08_RS05470	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KS08_RS05475	COG0564	pseudouridine synthase activity
KS08_RS05485	COG0569	domain protein
KS08_RS05485	COG0475	glutathione-regulated potassium exporter activity
KS08_RS05490	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KS08_RS05495	COG0352	thiamine-phosphate diphosphorylase activity
KS08_RS05500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KS08_RS05505	COG2104	thiamine diphosphate biosynthetic process
KS08_RS05515	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KS08_RS05520	COG0351	phosphomethylpyrimidine kinase
KS08_RS05525	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KS08_RS05580	COG0210	DNA helicase
KS08_RS05590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KS08_RS05600	COG1131	(ABC) transporter
KS08_RS05610	COG2153	protein acetylation
KS08_RS05620	COG2382	esterase
KS08_RS05625	COG0626	cystathionine gamma-synthase activity
KS08_RS05630	COG0626	cystathionine gamma-synthase activity
KS08_RS05640	COG0582	viral genome integration into host DNA
KS08_RS05645	COG2856	Zn peptidase
KS08_RS05655	COG1525	nuclease
KS08_RS05660	COG3620	sequence-specific DNA binding
KS08_RS05710	COG3935	DnaD domain protein
KS08_RS05715	COG1484	DNA-dependent DNA replication
KS08_RS05720	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
KS08_RS05790	COG3677	Transposase
KS08_RS05805	COG5484	DNA packaging
KS08_RS05880	COG5280	Phage tail tape measure protein TP901
KS08_RS05880	COG3953	SLT domain
KS08_RS05970	COG5444	nuclease activity
KS08_RS06005	COG4282	regulation of fungal-type cell wall biogenesis
KS08_RS06030	COG5290	Psort location Cytoplasmic, score
KS08_RS06035	COG5290	Psort location Cytoplasmic, score
KS08_RS06045	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KS08_RS06090	COG2367	Beta-lactamase
KS08_RS06095	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KS08_RS06100	COG0477	Major facilitator Superfamily
KS08_RS06105	COG1846	Transcriptional regulator
KS08_RS06115	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KS08_RS06115	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KS08_RS06120	COG1447	Phosphotransferase system cellobiose-specific component IIA
KS08_RS06125	COG2723	6-phospho-beta-galactosidase activity
KS08_RS06130	COG1349	DNA-binding transcription factor activity
KS08_RS06150	COG1285	pathogenesis
KS08_RS06155	COG2205	protein histidine kinase activity
KS08_RS06165	COG3383	formate dehydrogenase (NAD+) activity
KS08_RS06170	COG2427	Protein of unknown function (DUF1641)
KS08_RS06175	COG2124	cytochrome p450
KS08_RS06180	COG1819	glycosyl
KS08_RS06190	COG1587	Uroporphyrinogen-III synthase
KS08_RS06195	COG0390	transport system, permease component
KS08_RS06200	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KS08_RS06205	COG0697	spore germination
KS08_RS06210	COG4297	protein containing double-stranded beta helix domain
KS08_RS06220	COG1252	NADH dehydrogenase
KS08_RS06230	COG1609	Transcriptional regulator
KS08_RS06235	COG2721	sulfolactate sulfo-lyase activity
KS08_RS06240	COG0745	RESPONSE REGULATOR receiver
KS08_RS06245	COG2205	protein histidine kinase activity
KS08_RS06245	COG2770	Histidine kinase
KS08_RS06255	COG0730	response to heat
KS08_RS06260	COG2318	DinB family
KS08_RS06265	COG0457	Tetratricopeptide repeat
KS08_RS06275	COG3409	Peptidoglycan-binding domain 1 protein
KS08_RS06275	COG1388	LysM domain
KS08_RS06275	COG5632	N-Acetylmuramoyl-L-alanine amidase
KS08_RS06285	COG4195	phage-related replication protein
KS08_RS06290	COG2856	Zn peptidase
KS08_RS06295	COG1396	sequence-specific DNA binding
KS08_RS06305	COG1522	sequence-specific DNA binding
KS08_RS06310	COG1484	DNA-dependent DNA replication
KS08_RS06325	COG1595	DNA-templated transcription, initiation
KS08_RS06330	COG5484	DNA packaging
KS08_RS06330	COG3728	DNA packaging
KS08_RS06335	COG1783	phage Terminase large subunit
KS08_RS06340	COG5518	Phage portal protein
KS08_RS06345	COG0338	D12 class N6 adenine-specific DNA methyltransferase
KS08_RS06350	COG4653	Phage capsid family
KS08_RS06395	COG5412	phage tail tape measure protein
KS08_RS06395	COG5412	phage tail tape measure protein
KS08_RS06395	COG3953	SLT domain
KS08_RS06395	COG3953	SLT domain
KS08_RS06395	COG3953	SLT domain
KS08_RS06395	COG5412	phage tail tape measure protein
KS08_RS06400	COG1652	LysM domain
KS08_RS06405	COG4193	domain, Protein
KS08_RS06415	COG3628	GPW Gp25 family protein
KS08_RS06420	COG3299	homolog of phage Mu protein gp47
KS08_RS06425	COG3778	Protein conserved in bacteria
KS08_RS06465	COG3409	Peptidoglycan-binding domain 1 protein
KS08_RS06465	COG5632	N-Acetylmuramoyl-L-alanine amidase
KS08_RS06480	COG0306	phosphate transporter
KS08_RS06485	COG1392	Phosphate transport regulator
KS08_RS06490	COG0531	amino acid
KS08_RS06495	COG0346	lactoylglutathione lyase activity
KS08_RS06500	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KS08_RS06505	COG0463	Glycosyl transferase, family 2
KS08_RS06510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KS08_RS06515	COG0477	Major facilitator Superfamily
KS08_RS06520	COG2362	D-Aminopeptidase
KS08_RS06525	COG0601	transmembrane transport
KS08_RS06530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KS08_RS06535	COG0444	Belongs to the ABC transporter superfamily
KS08_RS06540	COG4166	transmembrane transport
KS08_RS06545	COG1619	proteins homologs of microcin C7 resistance protein MccF
KS08_RS06550	COG4948	Mandelate Racemase Muconate Lactonizing
KS08_RS06555	COG0791	NLP P60 protein
KS08_RS06560	COG4608	Belongs to the ABC transporter superfamily
KS08_RS06565	COG2706	6-phosphogluconolactonase activity
KS08_RS06570	COG1834	amidinotransferase
KS08_RS06575	COG1607	acyl-coa hydrolase
KS08_RS06580	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KS08_RS06585	COG2076	Multidrug Resistance protein
KS08_RS06590	COG2076	Multidrug Resistance protein
KS08_RS06600	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KS08_RS06610	COG1764	response to oxidative stress
KS08_RS06615	COG1846	Transcriptional regulator
KS08_RS06620	COG1764	response to oxidative stress
KS08_RS06635	COG0457	Tetratricopeptide repeat
KS08_RS06635	COG0463	Glycosyl transferase, family 2
KS08_RS06650	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KS08_RS06660	COG1404	Belongs to the peptidase S8 family
KS08_RS06665	COG1366	Belongs to the anti-sigma-factor antagonist family
KS08_RS06670	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KS08_RS06675	COG1122	ATPase activity
KS08_RS06680	COG4721	ABC-type cobalt transport system, permease component
KS08_RS06685	COG1388	LysM domain
KS08_RS06685	COG3858	chitin binding
KS08_RS06690	COG2239	Acts as a magnesium transporter
KS08_RS06695	COG0789	Transcriptional regulator
KS08_RS06705	COG1846	Transcriptional regulator
KS08_RS06710	COG0726	polysaccharide deacetylase
KS08_RS06715	COG1793	dna ligase
KS08_RS06715	COG3285	dna ligase
KS08_RS06720	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KS08_RS06725	COG3300	MHYT domain
KS08_RS06725	COG5001	Diguanylate cyclase
KS08_RS06730	COG0586	Pfam SNARE associated Golgi protein
KS08_RS06735	COG0861	Integral membrane protein TerC family
KS08_RS06740	COG1191	sigma factor activity
KS08_RS06765	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KS08_RS06770	COG2323	membrane
KS08_RS06775	COG3594	Acyltransferase
KS08_RS06780	COG5002	protein histidine kinase activity
KS08_RS06785	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KS08_RS06800	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KS08_RS06805	COG0436	Aminotransferase
KS08_RS06835	COG3852	Histidine kinase
KS08_RS06840	COG1846	Transcriptional regulator
KS08_RS06845	COG1360	Flagellar Motor Protein
KS08_RS06850	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KS08_RS06855	COG0542	response to heat
KS08_RS06860	COG3949	Membrane
KS08_RS06875	COG0720	synthase
KS08_RS06880	COG0602	queuosine metabolic process
KS08_RS06895	COG4873	Protein conserved in bacteria
KS08_RS06905	COG3773	Cell wall hydrolase
KS08_RS06910	COG2244	polysaccharide biosynthetic process
KS08_RS06915	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KS08_RS06920	COG2217	Heavy metal translocating P-type atpase
KS08_RS06925	COG0006	proline dipeptidase activity
KS08_RS06930	COG1609	Transcriptional regulator
KS08_RS06935	COG3711	transcriptional antiterminator
KS08_RS06940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KS08_RS06940	COG1263	PTS System
KS08_RS06940	COG2190	(PTS) system
KS08_RS06945	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KS08_RS06950	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KS08_RS06960	COG1533	DNA photolyase activity
KS08_RS06965	COG0840	transmembrane signaling receptor activity
KS08_RS06970	COG2084	Dehydrogenase
KS08_RS06980	COG2340	Cysteine-rich secretory protein family
KS08_RS06985	COG0768	penicillin binding
KS08_RS06990	COG4191	Histidine kinase
KS08_RS06995	COG0436	Aminotransferase
KS08_RS07000	COG0835	chemotaxis
KS08_RS07000	COG0784	Response regulator, receiver
KS08_RS07010	COG2814	Major facilitator Superfamily
KS08_RS07015	COG1376	ErfK ybiS ycfS ynhG family protein
KS08_RS07020	COG1408	metallophosphoesterase
KS08_RS07025	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_RS07035	COG2200	EAL domain
KS08_RS07040	COG4703	Protein of unknown function (DUF1797)
KS08_RS07045	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KS08_RS07055	COG0517	IMP dehydrogenase activity
KS08_RS07060	COG0583	DNA-binding transcription factor activity
KS08_RS07065	COG0716	FMN binding
KS08_RS07075	COG0716	FMN binding
KS08_RS07095	COG0668	transmembrane transport
KS08_RS07105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KS08_RS07125	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KS08_RS07130	COG0303	'Molybdopterin
KS08_RS07135	COG1763	Mo-molybdopterin cofactor biosynthetic process
KS08_RS07140	COG0314	molybdopterin synthase activity
KS08_RS07145	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KS08_RS07155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KS08_RS07160	COG1136	(ABC) transporter
KS08_RS07165	COG0577	efflux transmembrane transporter activity
KS08_RS07170	COG1349	DNA-binding transcription factor activity
KS08_RS07175	COG1105	Belongs to the carbohydrate kinase PfkB family
KS08_RS07180	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KS08_RS07180	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KS08_RS07180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KS08_RS07185	COG0681	Belongs to the peptidase S26 family
KS08_RS07195	COG0488	(ABC) transporter
KS08_RS07200	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KS08_RS07205	COG2309	aminopeptidase activity
KS08_RS07210	COG1077	Cell shape determining protein MreB Mrl
KS08_RS07215	COG2002	toxin-antitoxin pair type II binding
KS08_RS07220	COG3852	Histidine kinase
KS08_RS07225	COG2105	PFAM AIG2 family protein
KS08_RS07225	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
KS08_RS07230	COG0569	domain protein
KS08_RS07240	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KS08_RS07250	COG0561	phosphatase activity
KS08_RS07255	COG0242	peptide deformylase activity
KS08_RS07265	COG0497	DNA recombination
KS08_RS07270	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KS08_RS07275	COG0022	dehydrogenase e1 component
KS08_RS07280	COG0508	dehydrogenase complex catalyzes the overall conversion of
KS08_RS07285	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KS08_RS07290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KS08_RS07300	COG1982	Orn Lys Arg decarboxylase major
KS08_RS07320	COG0483	inositol monophosphate 1-phosphatase activity
KS08_RS07330	COG3227	Zinc metalloprotease (Elastase)
KS08_RS07355	COG1217	gtp-binding protein TYPA
KS08_RS07365	COG4896	Protein conserved in bacteria
KS08_RS07375	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KS08_RS07380	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KS08_RS07385	COG2066	Belongs to the glutaminase family
KS08_RS07395	COG0772	Belongs to the SEDS family
KS08_RS07400	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KS08_RS07415	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KS08_RS07415	COG2010	Cytochrome c
KS08_RS07420	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KS08_RS07425	COG1845	cytochrome c oxidase, subunit III
KS08_RS07430	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KS08_RS07435	COG3336	cytochrome c oxidase
KS08_RS07445	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KS08_RS07450	COG2340	Cysteine-rich secretory protein family
KS08_RS07465	COG3679	Belongs to the UPF0342 family
KS08_RS07475	COG0742	ribosomal rna small subunit methyltransferase
KS08_RS07485	COG3314	Sporulation integral membrane protein YlbJ
KS08_RS07490	COG1752	Esterase of the alpha-beta hydrolase superfamily
KS08_RS07495	COG3480	Lon protease (S16) C-terminal proteolytic domain
KS08_RS07505	COG1399	metal-binding, possibly nucleic acid-binding protein
KS08_RS07520	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KS08_RS07540	COG4839	cell division protein FtsL
KS08_RS07545	COG0768	penicillin binding
KS08_RS07550	COG0768	penicillin binding
KS08_RS07570	COG0772	Belongs to the SEDS family
KS08_RS07585	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KS08_RS07590	COG0849	cell division
KS08_RS07595	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KS08_RS07600	COG1404	Belongs to the peptidase S8 family
KS08_RS07600	COG4412	M6 family metalloprotease domain protein
KS08_RS07610	COG1191	sigma factor activity
KS08_RS07615	COG1191	sigma factor activity
KS08_RS07620	COG1119	ATPase activity
KS08_RS07625	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KS08_RS07630	COG1873	PFAM PRC-barrel domain
KS08_RS07635	COG1496	oxidoreductase activity
KS08_RS07640	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KS08_RS07650	COG0762	integral membrane protein
KS08_RS07655	COG2302	S4 RNA-binding domain
KS08_RS07660	COG3599	regulation of cell shape
KS08_RS07670	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KS08_RS07675	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KS08_RS07685	COG0564	pseudouridine synthase activity
KS08_RS07695	COG2233	PERMEase
KS08_RS07705	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KS08_RS07710	COG0505	Belongs to the CarA family
KS08_RS07715	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KS08_RS07730	COG0284	orotidine-5'-phosphate decarboxylase activity
KS08_RS07735	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KS08_RS07750	COG0306	phosphate transporter
KS08_RS07765	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KS08_RS07770	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
KS08_RS07775	COG1648	precorrin-2 dehydrogenase activity
KS08_RS07790	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KS08_RS07795	COG1561	YicC-like family, N-terminal region
KS08_RS07805	COG0194	GDP metabolic process
KS08_RS07815	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KS08_RS07820	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KS08_RS07825	COG0242	peptide deformylase activity
KS08_RS07835	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KS08_RS07835	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KS08_RS07845	COG0631	protein serine/threonine phosphatase activity
KS08_RS07850	COG0515	serine threonine protein kinase
KS08_RS07850	COG2815	serine threonine protein kinase
KS08_RS07860	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KS08_RS07865	COG1564	THIamine pyrophosphokinase
KS08_RS07880	COG1302	Protein conserved in bacteria
KS08_RS07885	COG1461	Dihydroxyacetone kinase
KS08_RS07890	COG1760	l-serine dehydratase
KS08_RS07895	COG1760	l-serine dehydratase
KS08_RS07900	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KS08_RS07915	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KS08_RS07920	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_RS07935	COG1196	nuclear chromosome segregation
KS08_RS07940	COG0552	protein localization to endoplasmic reticulum
KS08_RS07950	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KS08_RS07960	COG1837	Belongs to the UPF0109 family
KS08_RS07985	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KS08_RS08000	COG2257	FlhB HrpN YscU SpaS Family
KS08_RS08010	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KS08_RS08015	COG0758	DNA mediated transformation
KS08_RS08020	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KS08_RS08030	COG4974	Belongs to the 'phage' integrase family
KS08_RS08055	COG1558	bacterial-type flagellum-dependent cell motility
KS08_RS08060	COG1677	Flagellar hook-basal body complex protein FliE
KS08_RS08065	COG1766	The M ring may be actively involved in energy transduction
KS08_RS08070	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KS08_RS08075	COG1317	bacterial-type flagellum organization
KS08_RS08080	COG1157	protein secretion by the type III secretion system
KS08_RS08085	COG2882	bacterial-type flagellum organization
KS08_RS08090	COG3334	PFAM MgtE intracellular
KS08_RS08095	COG3144	bacterial-type flagellum assembly
KS08_RS08100	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
KS08_RS08105	COG4786	Flagellar basal body rod
KS08_RS08110	COG1582	Flagellar protein (FlbD)
KS08_RS08115	COG1580	Controls the rotational direction of flagella during chemotaxis
KS08_RS08120	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KS08_RS08125	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KS08_RS08125	COG1776	CheC inhibitor of MCP methylation
KS08_RS08130	COG2201	protein-glutamate methylesterase activity
KS08_RS08135	COG3190	flagellar
KS08_RS08140	COG1338	Plays a role in the flagellum-specific transport system
KS08_RS08145	COG1987	bacterial-type flagellum assembly
KS08_RS08150	COG1684	flagellar biosynthetic protein fliR
KS08_RS08155	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KS08_RS08160	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KS08_RS08165	COG1419	protein localization to endoplasmic reticulum
KS08_RS08170	COG0455	bacterial-type flagellum organization
KS08_RS08175	COG2201	protein-glutamate methylesterase activity
KS08_RS08180	COG0643	Histidine kinase
KS08_RS08180	COG2198	Histidine kinase
KS08_RS08185	COG0835	chemotaxis
KS08_RS08190	COG1776	CheC inhibitor of MCP methylation
KS08_RS08200	COG1191	sigma factor activity
KS08_RS08230	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KS08_RS08235	COG4589	Belongs to the CDS family
KS08_RS08245	COG0750	zinc metalloprotease
KS08_RS08255	COG2176	DNA-directed DNA polymerase activity
KS08_RS08265	COG0195	Participates in both transcription termination and antitermination
KS08_RS08270	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KS08_RS08275	COG1358	cellular component organization or biogenesis
KS08_RS08285	COG1550	Protein conserved in bacteria
KS08_RS08300	COG0196	riboflavin kinase activity
KS08_RS08315	COG0726	polysaccharide deacetylase
KS08_RS08320	COG0612	Peptidase, M16
KS08_RS08325	COG1873	PFAM PRC-barrel domain
KS08_RS08330	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KS08_RS08335	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KS08_RS08340	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KS08_RS08345	COG0527	aspartate kinase activity
KS08_RS08355	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KS08_RS08360	COG0740	serine-type endopeptidase activity
KS08_RS08370	COG1674	ftsk spoiiie
KS08_RS08370	COG4980	gas vesicle protein
KS08_RS08375	COG2188	Transcriptional regulator
KS08_RS08380	COG2814	Major facilitator Superfamily
KS08_RS08385	COG1846	Transcriptional regulator
KS08_RS08390	COG1033	growth of symbiont in host cell
KS08_RS08390	COG2409	Drug exporters of the RND superfamily
KS08_RS08395	COG0612	Peptidase, M16
KS08_RS08400	COG0612	Peptidase, M16
KS08_RS08405	COG0300	oxidoreductase activity
KS08_RS08420	COG1426	Protein conserved in bacteria
KS08_RS08425	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KS08_RS08440	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KS08_RS08450	COG1692	metallophosphoesterase
KS08_RS08455	COG2359	stage V sporulation protein S
KS08_RS08475	COG4550	Control of competence regulator ComK, YlbF/YmcA
KS08_RS08515	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KS08_RS08520	COG3425	synthase
KS08_RS08525	COG1024	Enoyl-CoA hydratase
KS08_RS08530	COG1024	Enoyl-CoA hydratase
KS08_RS08535	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KS08_RS08535	COG0300	oxidoreductase activity
KS08_RS08535	COG0318	PFAM AMP-dependent synthetase and ligase
KS08_RS08535	COG3321	synthase
KS08_RS08535	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_RS08540	COG0300	oxidoreductase activity
KS08_RS08540	COG3321	synthase
KS08_RS08540	COG4221	oxidoreductase activity
KS08_RS08540	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KS08_RS08545	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_RS08545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KS08_RS08545	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KS08_RS08545	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_RS08545	COG3321	synthase
KS08_RS08545	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KS08_RS08545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KS08_RS08545	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KS08_RS08545	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KS08_RS08545	COG3321	synthase
KS08_RS08550	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_RS08550	COG4221	oxidoreductase activity
KS08_RS08550	COG3321	synthase
KS08_RS08550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KS08_RS08555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KS08_RS08555	COG3321	synthase
KS08_RS08555	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KS08_RS08555	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KS08_RS08560	COG2124	cytochrome p450
KS08_RS08565	COG3209	COG3209 Rhs family protein
KS08_RS08570	COG3619	membrane
KS08_RS08580	COG1404	Belongs to the peptidase S8 family
KS08_RS08590	COG4195	phage-related replication protein
KS08_RS08595	COG1764	response to oxidative stress
KS08_RS08605	COG2076	Multidrug Resistance protein
KS08_RS08645	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KS08_RS08650	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KS08_RS08655	COG4112	unkown
KS08_RS08670	COG0464	growth
KS08_RS08675	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KS08_RS08680	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KS08_RS08685	COG0789	Transcriptional regulator
KS08_RS08690	COG0174	glutamine synthetase
KS08_RS08715	COG0726	polysaccharide deacetylase
KS08_RS08720	COG2124	cytochrome p450
KS08_RS08725	COG2211	Major facilitator Superfamily
KS08_RS08730	COG3507	Belongs to the glycosyl hydrolase 43 family
KS08_RS08745	COG1070	Carbohydrate kinase
KS08_RS08755	COG0574	Belongs to the PEP-utilizing enzyme family
KS08_RS08755	COG3848	Pyruvate phosphate dikinase
KS08_RS08765	COG1063	alcohol dehydrogenase
KS08_RS08775	COG0457	Tetratricopeptide repeat
KS08_RS08785	COG2318	DinB family
KS08_RS08790	COG1064	alcohol dehydrogenase
KS08_RS08815	COG0456	acetyltransferase
KS08_RS08850	COG3397	chitin binding
KS08_RS08865	COG5434	Belongs to the glycosyl hydrolase 28 family
KS08_RS08870	COG2314	TM2 domain
KS08_RS08875	COG0756	dUTP diphosphatase activity
KS08_RS08885	COG4195	phage-related replication protein
KS08_RS08915	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KS08_RS08925	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KS08_RS08945	COG0785	Cytochrome C biogenesis protein
KS08_RS08950	COG2201	protein-glutamate methylesterase activity
KS08_RS08955	COG4846	Membrane protein involved in cytochrome C biogenesis
KS08_RS08965	COG0071	Belongs to the small heat shock protein (HSP20) family
KS08_RS08980	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KS08_RS08985	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KS08_RS09000	COG0824	Thioesterase
KS08_RS09010	COG4841	protein insertion into membrane
KS08_RS09020	COG1832	CoA-binding protein
KS08_RS09025	COG0187	DNA topoisomerase II activity
KS08_RS09030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KS08_RS09040	COG1115	amino acid carrier protein
KS08_RS09070	COG2205	protein histidine kinase activity
KS08_RS09075	COG0745	RESPONSE REGULATOR receiver
KS08_RS09085	COG3507	Belongs to the glycosyl hydrolase 43 family
KS08_RS09110	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_RS09115	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KS08_RS09120	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KS08_RS09125	COG2124	cytochrome p450
KS08_RS09145	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KS08_RS09155	COG2246	polysaccharide biosynthetic process
KS08_RS09160	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KS08_RS09165	COG0586	Pfam SNARE associated Golgi protein
KS08_RS09170	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KS08_RS09175	COG1024	Enoyl-CoA hydratase
KS08_RS09180	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KS08_RS09185	COG0511	ligase activity, forming carbon-carbon bonds
KS08_RS09190	COG0439	Biotin carboxylase
KS08_RS09195	COG0318	PFAM AMP-dependent synthetase and ligase
KS08_RS09200	COG1960	acyl-CoA dehydrogenase activity
KS08_RS09205	COG1649	PFAM Uncharacterised BCR, COG1649
KS08_RS09215	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KS08_RS09215	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KS08_RS09220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KS08_RS09225	COG2027	D-alanyl-D-alanine carboxypeptidase
KS08_RS09230	COG2017	converts alpha-aldose to the beta-anomer
KS08_RS09235	COG0534	Mate efflux family protein
KS08_RS09250	COG0582	viral genome integration into host DNA
KS08_RS09255	COG0166	Belongs to the GPI family
KS08_RS09260	COG0405	Gamma-glutamyltransferase
KS08_RS09265	COG2814	Major facilitator Superfamily
KS08_RS09270	COG0640	Transcriptional regulator
KS08_RS09275	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KS08_RS09285	COG0604	alcohol dehydrogenase
KS08_RS09295	COG0493	'glutamate synthase
KS08_RS09300	COG0069	glutamate synthase activity
KS08_RS09300	COG0067	glutamate synthase
KS08_RS09300	COG0070	glutamate synthase
KS08_RS09305	COG0583	DNA-binding transcription factor activity
KS08_RS09310	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KS08_RS09325	COG0300	oxidoreductase activity
KS08_RS09330	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KS08_RS09340	COG2814	Major facilitator Superfamily
KS08_RS09345	COG1070	Carbohydrate kinase
KS08_RS09350	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KS08_RS09355	COG0243	molybdopterin cofactor binding
KS08_RS09385	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KS08_RS09390	COG0662	Cupin 2, conserved barrel domain protein
KS08_RS09390	COG2207	Transcriptional regulator
KS08_RS09395	COG1309	transcriptional regulator
KS08_RS09400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KS08_RS09410	COG0640	Transcriptional regulator
KS08_RS09415	COG0741	lytic transglycosylase activity
KS08_RS09420	COG2322	membrane
KS08_RS09435	COG1619	proteins homologs of microcin C7 resistance protein MccF
KS08_RS09445	COG3584	3D domain protein
KS08_RS09445	COG1388	LysM domain
KS08_RS09450	COG0514	ATP-dependent DNA helicase (RecQ)
KS08_RS09460	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KS08_RS09465	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KS08_RS09480	COG0071	Belongs to the small heat shock protein (HSP20) family
KS08_RS09510	COG1012	belongs to the aldehyde dehydrogenase family
KS08_RS09515	COG1657	PFAM Prenyltransferase squalene oxidase
KS08_RS09520	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KS08_RS09525	COG0733	neurotransmitter:sodium symporter activity
KS08_RS09530	COG0385	Bile acid
KS08_RS09535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KS08_RS09540	COG0508	dehydrogenase complex catalyzes the overall conversion of
KS08_RS09550	COG4548	von Willebrand factor, type A
KS08_RS09555	COG0714	Associated with various cellular activities
KS08_RS09560	COG2032	superoxide dismutase activity
KS08_RS09565	COG0791	NLP P60 protein
KS08_RS09565	COG1388	LysM domain
KS08_RS09570	COG1819	glycosyl
KS08_RS09575	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KS08_RS09580	COG0534	Mate efflux family protein
KS08_RS09585	COG1366	Belongs to the anti-sigma-factor antagonist family
KS08_RS09590	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KS08_RS09595	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KS08_RS09605	COG2962	Rard protein
KS08_RS09620	COG1942	4-Oxalocrotonate Tautomerase
KS08_RS09630	COG1733	regulation of RNA biosynthetic process
KS08_RS09635	COG0778	Nitroreductase
KS08_RS09640	COG0400	carboxylic ester hydrolase activity
KS08_RS09645	COG0346	lactoylglutathione lyase activity
KS08_RS09655	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KS08_RS09665	COG2723	6-phospho-beta-galactosidase activity
KS08_RS09670	COG2188	Transcriptional regulator
KS08_RS09675	COG3409	Peptidoglycan-binding domain 1 protein
KS08_RS09675	COG0793	Belongs to the peptidase S41A family
KS08_RS09680	COG2226	methyltransferase
KS08_RS09690	COG1876	peptidase activity
KS08_RS09705	COG0671	phosphoesterase, PA-phosphatase related
KS08_RS09720	COG0346	lactoylglutathione lyase activity
KS08_RS09735	COG1509	lysine 2,3-aminomutase activity
KS08_RS09740	COG0456	acetyltransferase
KS08_RS09745	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KS08_RS09750	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KS08_RS09755	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KS08_RS09760	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KS08_RS09770	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
KS08_RS09780	COG0456	acetyltransferase
KS08_RS09785	COG0463	Glycosyl transferase, family 2
KS08_RS09800	COG4641	Protein conserved in bacteria
KS08_RS09810	COG1086	Polysaccharide biosynthesis protein
KS08_RS09835	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KS08_RS09840	COG1086	Polysaccharide biosynthesis protein
KS08_RS09855	COG1846	Transcriptional regulator
KS08_RS09860	COG4698	Protein conserved in bacteria
KS08_RS09865	COG2755	lipolytic protein G-D-S-L family
KS08_RS09870	COG1999	signal sequence binding
KS08_RS09880	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KS08_RS09885	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KS08_RS09890	COG1272	protein, Hemolysin III
KS08_RS09895	COG0204	Acyl-transferase
KS08_RS09900	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KS08_RS09905	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KS08_RS09915	COG2136	Putative SAM-dependent methyltransferase
KS08_RS09915	COG2521	methyltransferase
KS08_RS09930	COG1413	lyase activity
KS08_RS09935	COG1418	mRNA catabolic process
KS08_RS09940	COG0386	Belongs to the glutathione peroxidase family
KS08_RS09950	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KS08_RS09955	COG1278	Cold shock
KS08_RS09975	COG0328	RNA-DNA hybrid ribonuclease activity
KS08_RS09980	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KS08_RS09985	COG0328	RNA-DNA hybrid ribonuclease activity
KS08_RS09995	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KS08_RS10005	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KS08_RS10010	COG1755	Isoprenylcysteine carboxyl methyltransferase
KS08_RS10015	COG3424	synthase
KS08_RS10035	COG2233	PERMEase
KS08_RS10040	COG3331	DNA recombination
KS08_RS10070	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KS08_RS10075	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KS08_RS10095	COG0756	dUTP diphosphatase activity
KS08_RS10130	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KS08_RS10145	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KS08_RS10145	COG1372	Participates in initiation and elongation during chromosome replication
KS08_RS10150	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KS08_RS10150	COG1372	Participates in initiation and elongation during chromosome replication
KS08_RS10155	COG1780	Probably involved in ribonucleotide reductase function
KS08_RS10235	COG0270	DNA (cytosine-5-)-methyltransferase activity
KS08_RS10245	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
KS08_RS10250	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KS08_RS10260	COG3584	3D domain protein
KS08_RS10270	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KS08_RS10310	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KS08_RS10315	COG3420	alginic acid biosynthetic process
KS08_RS10315	COG5434	Belongs to the glycosyl hydrolase 28 family
KS08_RS10320	COG4195	phage-related replication protein
KS08_RS10355	COG2135	peptidase activity
KS08_RS10360	COG1793	dna ligase
KS08_RS10480	COG0582	viral genome integration into host DNA
KS08_RS10570	COG3655	Transcriptional regulator
KS08_RS10600	COG3645	SOS response
KS08_RS10600	COG3646	Phage regulatory protein
KS08_RS10605	COG0210	DNA helicase
KS08_RS10660	COG0776	regulation of translation
KS08_RS10780	COG0582	viral genome integration into host DNA
KS08_RS10795	COG0515	serine threonine protein kinase
KS08_RS10795	COG2815	serine threonine protein kinase
KS08_RS10830	COG2433	Pfam Transposase IS66
KS08_RS10845	COG5434	Belongs to the glycosyl hydrolase 28 family
KS08_RS10850	COG5632	N-Acetylmuramoyl-L-alanine amidase
KS08_RS10850	COG3409	Peptidoglycan-binding domain 1 protein
KS08_RS10880	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KS08_RS10905	COG5444	nuclease activity
KS08_RS10915	COG4282	regulation of fungal-type cell wall biogenesis
KS08_RS10920	COG1525	nuclease
KS08_RS10930	COG2233	PERMEase
KS08_RS10940	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KS08_RS10945	COG1199	ATP-dependent helicase activity
KS08_RS10960	COG0116	Belongs to the methyltransferase superfamily
KS08_RS10975	COG3359	exonuclease
KS08_RS10980	COG1111	helicase
KS08_RS10980	COG1205	dead DEAH box helicase
KS08_RS10985	COG2190	(PTS) system
KS08_RS11030	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KS08_RS11030	COG4499	WXG100 protein secretion system (Wss), protein YukC
KS08_RS11040	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KS08_RS11045	COG3935	DnaD domain protein
KS08_RS11055	COG0436	Aminotransferase
KS08_RS11060	COG5353	protein conserved in bacteria
KS08_RS11065	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KS08_RS11065	COG1199	ATP-dependent helicase activity
KS08_RS11095	COG0438	transferase activity, transferring glycosyl groups
KS08_RS11100	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KS08_RS11115	COG1694	Mazg nucleotide pyrophosphohydrolase
KS08_RS11120	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KS08_RS11125	COG2140	Oxalate decarboxylase
KS08_RS11135	COG4347	Protein of unknown function (DUF1405)
KS08_RS11140	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KS08_RS11140	COG2010	Cytochrome c
KS08_RS11145	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KS08_RS11150	COG0723	plastoquinol--plastocyanin reductase activity
KS08_RS11165	COG0457	Tetratricopeptide repeat
KS08_RS11175	COG0287	Prephenate dehydrogenase
KS08_RS11210	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KS08_RS11215	COG4401	Chorismate mutase type I
KS08_RS11230	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KS08_RS11235	COG0105	UTP biosynthetic process
KS08_RS11240	COG0142	geranyltranstransferase activity
KS08_RS11250	COG0142	geranyltranstransferase activity
KS08_RS11265	COG0776	regulation of translation
KS08_RS11270	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KS08_RS11305	COG0539	negative regulation of cytoplasmic translation
KS08_RS11315	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
KS08_RS11320	COG2959	enzyme of heme biosynthesis
KS08_RS11325	COG3773	Cell wall hydrolase
KS08_RS11325	COG3409	Peptidoglycan-binding domain 1 protein
KS08_RS11330	COG2339	peptidase activity
KS08_RS11335	COG0492	ferredoxin-NADP+ reductase activity
KS08_RS11340	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KS08_RS11345	COG4862	establishment of competence for transformation
KS08_RS11350	COG1408	metallophosphoesterase
KS08_RS11360	COG1388	LysM domain
KS08_RS11365	COG1266	CAAX protease self-immunity
KS08_RS11370	COG0514	ATP-dependent DNA helicase (RecQ)
KS08_RS11375	COG4955	Helix-turn-helix domain
KS08_RS11380	COG1141	Ferredoxin
KS08_RS11385	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KS08_RS11390	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KS08_RS11400	COG1595	DNA-templated transcription, initiation
KS08_RS11405	COG5002	protein histidine kinase activity
KS08_RS11410	COG0745	RESPONSE REGULATOR receiver
KS08_RS11415	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KS08_RS11420	COG1333	cytochrome c biogenesis protein
KS08_RS11425	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KS08_RS11430	COG1187	pseudouridine synthase activity
KS08_RS11435	COG0700	Nucleoside recognition
KS08_RS11440	COG2715	membrane protein required for spore maturation
KS08_RS11445	COG1686	Belongs to the peptidase S11 family
KS08_RS11465	COG1547	Domain of unknown function (DUF309)
KS08_RS11470	COG0456	acetyltransferase
KS08_RS11475	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KS08_RS11480	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KS08_RS11480	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KS08_RS11485	COG0307	riboflavin synthase, alpha
KS08_RS11490	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KS08_RS11490	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KS08_RS11500	COG0681	Belongs to the peptidase S26 family
KS08_RS11510	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KS08_RS11515	COG4086	secreted protein
KS08_RS11520	COG0019	diaminopimelate decarboxylase activity
KS08_RS11525	COG0697	spore germination
KS08_RS11540	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KS08_RS11560	COG1191	sigma factor activity
KS08_RS11570	COG1366	Belongs to the anti-sigma-factor antagonist family
KS08_RS11575	COG1686	Belongs to the peptidase S11 family
KS08_RS11580	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KS08_RS11590	COG4974	Belongs to the 'phage' integrase family
KS08_RS11600	COG0735	belongs to the Fur family
KS08_RS11605	COG1300	Membrane
KS08_RS11620	COG0281	malic enzyme
KS08_RS11625	COG1757	Na H antiporter
KS08_RS11630	COG1027	Aspartate ammonia-lyase
KS08_RS11635	COG0252	asparaginase activity
KS08_RS11640	COG1396	sequence-specific DNA binding
KS08_RS11645	COG1379	DNA repair
KS08_RS11650	COG0494	nUDIX hydrolase
KS08_RS11660	COG0667	Aldo Keto reductase
KS08_RS11670	COG1073	alpha beta
KS08_RS11680	COG4918	Iron-sulphur cluster biosynthesis
KS08_RS11685	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KS08_RS11685	COG0456	acetyltransferase
KS08_RS11690	COG0456	acetyltransferase
KS08_RS11695	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KS08_RS11710	COG0628	permease
KS08_RS11720	COG3048	D-serine ammonia-lyase activity
KS08_RS11725	COG0300	oxidoreductase activity
KS08_RS11730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KS08_RS11735	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KS08_RS11760	COG0596	Alpha beta hydrolase
KS08_RS11775	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KS08_RS11780	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KS08_RS11795	COG0706	membrane insertase activity
KS08_RS11800	COG2195	Cleaves the N-terminal amino acid of tripeptides
KS08_RS11805	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KS08_RS11810	COG0346	lactoylglutathione lyase activity
KS08_RS11815	COG1376	ErfK ybiS ycfS ynhG family protein
KS08_RS11820	COG4129	membrane
KS08_RS11825	COG1126	abc transporter atp-binding protein
KS08_RS11830	COG0765	amino acid transport
KS08_RS11835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KS08_RS11845	COG1597	lipid kinase activity
KS08_RS11850	COG0508	dehydrogenase complex catalyzes the overall conversion of
KS08_RS11855	COG0022	dehydrogenase e1 component
KS08_RS11860	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KS08_RS11865	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KS08_RS11870	COG3426	butyrate kinase activity
KS08_RS11875	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KS08_RS11880	COG0280	phosphate acetyltransferase
KS08_RS11885	COG3829	transcription factor binding
KS08_RS11885	COG3290	protein histidine kinase activity
KS08_RS11895	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KS08_RS11900	COG2079	MmgE PrpD family protein
KS08_RS11905	COG0372	Belongs to the citrate synthase family
KS08_RS11910	COG1960	acyl-CoA dehydrogenase activity
KS08_RS11915	COG1250	3-hydroxyacyl-CoA dehydrogenase
KS08_RS11920	COG0183	Belongs to the thiolase family
KS08_RS11925	COG0584	glycerophosphoryl diester phosphodiesterase
KS08_RS11930	COG0860	N-Acetylmuramoyl-L-alanine amidase
KS08_RS11950	COG1902	pentaerythritol trinitrate reductase activity
KS08_RS11965	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KS08_RS11970	COG0745	RESPONSE REGULATOR receiver
KS08_RS11975	COG0750	zinc metalloprotease
KS08_RS11980	COG0497	DNA recombination
KS08_RS11990	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KS08_RS12000	COG0142	geranyltranstransferase activity
KS08_RS12010	COG1570	exodeoxyribonuclease VII activity
KS08_RS12025	COG1302	Protein conserved in bacteria
KS08_RS12030	COG0439	Biotin carboxylase
KS08_RS12035	COG0511	ligase activity, forming carbon-carbon bonds
KS08_RS12075	COG3854	ATPases associated with a variety of cellular activities
KS08_RS12090	COG0006	proline dipeptidase activity
KS08_RS12100	COG3872	metal-dependent enzyme
KS08_RS12110	COG1752	Esterase of the alpha-beta hydrolase superfamily
KS08_RS12125	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KS08_RS12145	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KS08_RS12160	COG1396	sequence-specific DNA binding
KS08_RS12170	COG0681	Belongs to the peptidase S26 family
KS08_RS12195	COG4940	Competence protein ComGF
KS08_RS12205	COG4970	Tfp pilus assembly protein FimT
KS08_RS12210	COG4537	Required for transformation and DNA binding
KS08_RS12215	COG1459	type II secretion system
KS08_RS12220	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KS08_RS12225	COG0598	Magnesium transport protein CorA
KS08_RS12230	COG1253	flavin adenine dinucleotide binding
KS08_RS12235	COG1366	Belongs to the anti-sigma-factor antagonist family
KS08_RS12245	COG1393	Belongs to the ArsC family
KS08_RS12255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KS08_RS12265	COG0011	TIGRFAM Protein of
KS08_RS12275	COG2866	Carboxypeptidase
KS08_RS12280	COG1940	carbohydrate kinase activity
KS08_RS12285	COG4483	Protein conserved in bacteria
KS08_RS12290	COG1757	Na H antiporter
KS08_RS12295	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KS08_RS12305	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KS08_RS12310	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KS08_RS12315	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KS08_RS12320	COG0581	inorganic phosphate transmembrane transporter activity
KS08_RS12325	COG0573	inorganic phosphate transmembrane transporter activity
KS08_RS12330	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KS08_RS12335	COG0768	penicillin binding
KS08_RS12340	COG0477	Major facilitator Superfamily
KS08_RS12345	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KS08_RS12350	COG2839	Protein conserved in bacteria
KS08_RS12355	COG5521	maltodextrose utilization protein MalA
KS08_RS12360	COG1388	LysM domain
KS08_RS12370	COG4709	membrane
KS08_RS12375	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
KS08_RS12380	COG0735	belongs to the Fur family
KS08_RS12385	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KS08_RS12400	COG0513	Belongs to the DEAD box helicase family
KS08_RS12415	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KS08_RS12420	COG2384	SAM-dependent methyltransferase
KS08_RS12425	COG2010	Cytochrome c
KS08_RS12430	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KS08_RS12435	COG0358	DNA primase activity
KS08_RS12450	COG0517	IMP dehydrogenase activity
KS08_RS12455	COG0751	glycine-tRNA ligase activity
KS08_RS12470	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KS08_RS12475	COG0295	cytidine deaminase activity
KS08_RS12480	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KS08_RS12490	COG1480	7TM receptor with intracellular HD hydrolase
KS08_RS12495	COG1702	phosphate starvation-inducible protein PhoH
KS08_RS12500	COG0561	phosphatase activity
KS08_RS12515	COG4864	UPF0365 protein
KS08_RS12520	COG1030	water channel activity
KS08_RS12525	COG1610	YqeY-like protein
KS08_RS12535	COG1283	sodium-dependent phosphate transmembrane transporter activity
KS08_RS12540	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KS08_RS12545	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KS08_RS12575	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KS08_RS12590	COG0860	N-Acetylmuramoyl-L-alanine amidase
KS08_RS12605	COG1466	dna polymerase III delta subunit
KS08_RS12615	COG0658	competence protein
KS08_RS12615	COG2333	competence protein COMEC
KS08_RS12620	COG2131	deaminase
KS08_RS12625	COG1555	photosystem II stabilization
KS08_RS12625	COG1596	polysaccharide export
KS08_RS12630	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KS08_RS12635	COG2226	methyltransferase
KS08_RS12640	COG0799	negative regulation of ribosome biogenesis
KS08_RS12645	COG1713	HD superfamily hydrolase involved in NAD metabolism
KS08_RS12655	COG1534	Rna-binding protein
KS08_RS12660	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KS08_RS12665	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KS08_RS12670	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KS08_RS12680	COG2755	lipolytic protein G-D-S-L family
KS08_RS12690	COG3409	Peptidoglycan-binding domain 1 protein
KS08_RS12690	COG5632	N-Acetylmuramoyl-L-alanine amidase
KS08_RS12695	COG0398	Pfam SNARE associated Golgi protein
KS08_RS12735	COG0563	adenylate kinase activity
KS08_RS12745	COG2814	Major facilitator Superfamily
KS08_RS12750	COG2318	DinB family
KS08_RS12755	COG0561	phosphatase activity
KS08_RS12760	COG0561	phosphatase activity
KS08_RS12770	COG1482	cell wall glycoprotein biosynthetic process
KS08_RS12775	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KS08_RS12775	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KS08_RS12775	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KS08_RS12780	COG3711	transcriptional antiterminator
KS08_RS12780	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KS08_RS12790	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KS08_RS12795	COG0583	DNA-binding transcription factor activity
KS08_RS12800	COG2814	Major facilitator Superfamily
KS08_RS12805	COG2124	cytochrome p450
KS08_RS12805	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KS08_RS12810	COG1309	transcriptional regulator
KS08_RS12815	COG2226	methyltransferase
KS08_RS12820	COG2116	formate transmembrane transporter activity
KS08_RS12825	COG5609	conserved protein (DUF2294)
KS08_RS12830	COG3383	formate dehydrogenase (NAD+) activity
KS08_RS12835	COG2427	Protein of unknown function (DUF1641)
KS08_RS12845	COG0626	cystathionine gamma-synthase activity
KS08_RS12850	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KS08_RS12875	COG0768	penicillin binding
KS08_RS12890	COG0826	peptidase U32
KS08_RS12895	COG0826	peptidase U32
KS08_RS12900	COG4122	O-methyltransferase activity
KS08_RS12905	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KS08_RS12920	COG4472	Bacterial protein of unknown function (DUF965)
KS08_RS12930	COG0628	permease
KS08_RS12935	COG1126	abc transporter atp-binding protein
KS08_RS12940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KS08_RS12945	COG0765	amino acid transport
KS08_RS12950	COG0765	amino acid transport
KS08_RS12960	COG3881	PFAM PRC-barrel domain
KS08_RS12965	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KS08_RS12970	COG0457	Tetratricopeptide repeat
KS08_RS12980	COG1104	cysteine desulfurase activity
KS08_RS12985	COG1959	2 iron, 2 sulfur cluster binding
KS08_RS12990	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KS08_RS12995	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KS08_RS13015	COG3103	Sh3 type 3 domain protein
KS08_RS13015	COG0860	N-Acetylmuramoyl-L-alanine amidase
KS08_RS13015	COG4991	sh3 domain protein
KS08_RS13020	COG1490	D-aminoacyl-tRNA deacylase activity
KS08_RS13025	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KS08_RS13035	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KS08_RS13035	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KS08_RS13040	COG5416	Lipopolysaccharide assembly protein A domain
KS08_RS13045	COG0490	domain, Protein
KS08_RS13050	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KS08_RS13050	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KS08_RS13060	COG2244	polysaccharide biosynthetic process
KS08_RS13065	COG2323	membrane
KS08_RS13075	COG1862	Preprotein translocase
KS08_RS13115	COG1388	LysM domain
KS08_RS13125	COG0157	Belongs to the NadC ModD family
KS08_RS13130	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KS08_RS13135	COG1104	cysteine desulfurase activity
KS08_RS13140	COG1827	regulation of RNA biosynthetic process
KS08_RS13145	COG0077	Prephenate dehydratase
KS08_RS13160	COG3290	protein histidine kinase activity
KS08_RS13165	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KS08_RS13170	COG2868	ribosomal protein
KS08_RS13180	COG1994	Peptidase M50
KS08_RS13185	COG0739	heme binding
KS08_RS13190	COG2894	cell division
KS08_RS13195	COG0850	regulation of cytokinetic process
KS08_RS13200	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KS08_RS13210	COG1077	Cell shape determining protein MreB Mrl
KS08_RS13230	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KS08_RS13235	COG0285	dihydrofolate synthase activity
KS08_RS13240	COG0525	valine-tRNA ligase activity
KS08_RS13250	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KS08_RS13255	COG1388	LysM domain
KS08_RS13265	COG0113	porphobilinogen synthase activity
KS08_RS13270	COG1587	Uroporphyrinogen-III synthase
KS08_RS13280	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KS08_RS13300	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KS08_RS13305	COG0470	DNA polymerase III
KS08_RS13305	COG1067	ATP-dependent peptidase activity
KS08_RS13320	COG1477	protein flavinylation
KS08_RS13320	COG0457	Tetratricopeptide repeat
KS08_RS13335	COG0473	3-isopropylmalate dehydrogenase activity
KS08_RS13350	COG0440	acetolactate synthase activity
KS08_RS13355	COG0028	Belongs to the TPP enzyme family
KS08_RS13380	COG0622	Phosphoesterase
KS08_RS13385	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KS08_RS13395	COG5401	PFAM Sporulation and spore germination
KS08_RS13405	COG1846	Transcriptional regulator
KS08_RS13410	COG2197	response regulator
KS08_RS13415	COG0824	Thioesterase
KS08_RS13420	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KS08_RS13425	COG1053	succinate dehydrogenase
KS08_RS13430	COG2009	succinate dehydrogenase
KS08_RS13435	COG1719	4-vinyl reductase, 4VR
KS08_RS13440	COG0527	aspartate kinase activity
KS08_RS13450	COG3118	belongs to the thioredoxin family
KS08_RS13455	COG3534	alpha-L-arabinofuranosidase
KS08_RS13460	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KS08_RS13465	COG2086	electron transfer activity
KS08_RS13470	COG1024	Enoyl-CoA hydratase
KS08_RS13475	COG1309	transcriptional regulator
KS08_RS13480	COG0318	PFAM AMP-dependent synthetase and ligase
KS08_RS13490	COG3766	membrane
KS08_RS13500	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KS08_RS13500	COG1796	DNA polymerase
KS08_RS13505	COG1286	toxin biosynthetic process
KS08_RS13520	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KS08_RS13520	COG0072	phenylalanine-tRNA ligase activity
KS08_RS13525	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KS08_RS13530	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KS08_RS13540	COG3835	regulator
KS08_RS13545	COG0277	FAD linked oxidase domain protein
KS08_RS13550	COG0247	lactate metabolic process
KS08_RS13555	COG1966	Carbon starvation protein
KS08_RS13560	COG3534	alpha-L-arabinofuranosidase
KS08_RS13565	COG0395	ABC-type sugar transport system, permease component
KS08_RS13570	COG1175	transmembrane transport
KS08_RS13575	COG1653	transport
KS08_RS13585	COG0647	UMP catabolic process
KS08_RS13590	COG0235	Class ii aldolase
KS08_RS13595	COG1069	ribulokinase activity
KS08_RS13600	COG2160	L-arabinose isomerase activity
KS08_RS13605	COG3507	Belongs to the glycosyl hydrolase 43 family
KS08_RS13610	COG1363	Peptidase, m42
KS08_RS13620	COG3326	Membrane
KS08_RS13625	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KS08_RS13635	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KS08_RS13640	COG1346	cytolysis
KS08_RS13645	COG1380	Effector of murein hydrolase LrgA
KS08_RS13650	COG3279	Response regulator of the LytR AlgR family
KS08_RS13655	COG3275	phosphorelay sensor kinase activity
KS08_RS13660	COG1011	Hydrolase
KS08_RS13675	COG0398	Pfam SNARE associated Golgi protein
KS08_RS13680	COG1484	DNA-dependent DNA replication
KS08_RS13685	COG3611	Membrane attachment protein
KS08_RS13700	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KS08_RS13705	COG1733	regulation of RNA biosynthetic process
KS08_RS13710	COG2814	Major facilitator Superfamily
KS08_RS13715	COG0656	L-ascorbic acid biosynthetic process
KS08_RS13720	COG0237	dephospho-CoA kinase activity
KS08_RS13725	COG1971	Probably functions as a manganese efflux pump
KS08_RS13730	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KS08_RS13735	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KS08_RS13735	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KS08_RS13740	COG5002	protein histidine kinase activity
KS08_RS13745	COG0745	RESPONSE REGULATOR receiver
KS08_RS13755	COG0538	isocitrate dehydrogenase activity
KS08_RS13760	COG0372	Belongs to the citrate synthase family
KS08_RS13770	COG0628	permease
KS08_RS13775	COG3030	protein affecting phage T7 exclusion by the F plasmid
KS08_RS13780	COG0469	pyruvate kinase activity
KS08_RS13805	COG0281	malic enzyme
KS08_RS13810	COG0587	DNA-directed DNA polymerase activity
KS08_RS13830	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KS08_RS13840	COG4109	DRTGG domain
KS08_RS13850	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_RS13865	COG0521	Mo-molybdopterin cofactor biosynthetic process
KS08_RS13875	COG0827	DNA restriction-modification system
KS08_RS13880	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KS08_RS13885	COG3874	Sporulation protein YtfJ
KS08_RS13895	COG1714	RDD family
KS08_RS13900	COG0616	signal peptide processing
KS08_RS13905	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KS08_RS13910	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KS08_RS13915	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KS08_RS13930	COG1104	cysteine desulfurase activity
KS08_RS13935	COG1114	Component of the transport system for branched-chain amino acids
KS08_RS13945	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KS08_RS13950	COG1309	transcriptional regulator
KS08_RS13955	COG1956	GAF domain-containing protein
KS08_RS13960	COG2203	Gaf domain
KS08_RS13960	COG2199	diguanylate cyclase activity
KS08_RS13970	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KS08_RS13970	COG1017	nitric oxide dioxygenase activity
KS08_RS13980	COG0693	protein deglycase activity
KS08_RS13995	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KS08_RS14000	COG1378	Sugar-specific transcriptional regulator TrmB
KS08_RS14005	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KS08_RS14020	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KS08_RS14025	COG0454	-acetyltransferase
KS08_RS14030	COG0517	IMP dehydrogenase activity
KS08_RS14035	COG0123	including yeast histone deacetylase and acetoin utilization protein
KS08_RS14040	COG1360	Flagellar Motor Protein
KS08_RS14045	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KS08_RS14050	COG1609	Transcriptional regulator
KS08_RS14055	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KS08_RS14055	COG1605	Chorismate mutase
KS08_RS14060	COG3118	belongs to the thioredoxin family
KS08_RS14065	COG4980	gas vesicle protein
KS08_RS14070	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KS08_RS14080	COG1674	ftsk spoiiie
KS08_RS14085	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KS08_RS14095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KS08_RS14105	COG1363	Peptidase, m42
KS08_RS14110	COG5584	Small secreted protein
KS08_RS14115	COG0281	malic enzyme
KS08_RS14120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KS08_RS14135	COG0510	thiamine kinase activity
KS08_RS14140	COG1597	lipid kinase activity
KS08_RS14150	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KS08_RS14155	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KS08_RS14160	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KS08_RS14165	COG2252	PERMEase
KS08_RS14170	COG4473	ABC transporter
KS08_RS14175	COG1131	(ABC) transporter
KS08_RS14180	COG1349	DNA-binding transcription factor activity
KS08_RS14185	COG1187	pseudouridine synthase activity
KS08_RS14190	COG2244	polysaccharide biosynthetic process
KS08_RS14195	COG2081	HI0933 family
KS08_RS14200	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KS08_RS14210	COG1609	Transcriptional regulator
KS08_RS14215	COG1653	transport
KS08_RS14220	COG1175	transmembrane transport
KS08_RS14225	COG0395	ABC-type sugar transport system, permease component
KS08_RS14230	COG1486	melibiose metabolic process
KS08_RS14240	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KS08_RS14255	COG2202	Pas domain
KS08_RS14255	COG1366	Belongs to the anti-sigma-factor antagonist family
KS08_RS14260	COG2814	Major facilitator Superfamily
KS08_RS14265	COG5522	Integral membrane protein (intg_mem_TP0381)
KS08_RS14270	COG0577	efflux transmembrane transporter activity
KS08_RS14275	COG1136	(ABC) transporter
KS08_RS14280	COG2205	protein histidine kinase activity
KS08_RS14285	COG0745	RESPONSE REGULATOR receiver
KS08_RS14290	COG0577	efflux transmembrane transporter activity
KS08_RS14295	COG1136	(ABC) transporter
KS08_RS14315	COG1131	(ABC) transporter
KS08_RS14320	COG1725	Transcriptional regulator
KS08_RS14335	COG1242	4 iron, 4 sulfur cluster binding
KS08_RS14340	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KS08_RS14355	COG2267	carboxylic ester hydrolase activity
KS08_RS14360	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KS08_RS14365	COG1113	amino acid transport
KS08_RS14370	COG0367	asparagine synthase
KS08_RS14390	COG1506	peptidase
KS08_RS14395	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KS08_RS14400	COG1116	anion transmembrane transporter activity
KS08_RS14405	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KS08_RS14410	COG0494	nUDIX hydrolase
KS08_RS14415	COG4824	toxin secretion phage lysis holin
KS08_RS14420	COG0783	Belongs to the Dps family
KS08_RS14445	COG0288	reversible hydration of carbon dioxide
KS08_RS14455	COG1271	oxidase subunit
KS08_RS14460	COG1294	oxidase, subunit
KS08_RS14465	COG4948	Mandelate Racemase Muconate Lactonizing
KS08_RS14475	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KS08_RS14480	COG0596	Alpha beta hydrolase
KS08_RS14490	COG1169	isochorismate synthase
KS08_RS14495	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KS08_RS14500	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
KS08_RS14625	COG3859	Proton-coupled thiamine transporter YuaJ
KS08_RS14630	COG2268	Band 7 protein
KS08_RS14635	COG1585	Membrane protein implicated in regulation of membrane protease activity
KS08_RS14640	COG2318	DinB family
KS08_RS14650	COG1454	alcohol dehydrogenase
KS08_RS14655	COG1012	belongs to the aldehyde dehydrogenase family
KS08_RS14660	COG1510	regulation of RNA biosynthetic process
KS08_RS14670	COG0569	domain protein
KS08_RS14675	COG1705	Flagellar rod assembly protein muramidase FlgJ
KS08_RS14680	COG1017	nitric oxide dioxygenase activity
KS08_RS14680	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KS08_RS14700	COG0457	Tetratricopeptide repeat
KS08_RS14755	COG5632	N-Acetylmuramoyl-L-alanine amidase
KS08_RS14760	COG4824	toxin secretion phage lysis holin
KS08_RS14780	COG5434	Belongs to the glycosyl hydrolase 28 family
KS08_RS14795	COG3953	SLT domain
KS08_RS14795	COG5412	phage tail tape measure protein
KS08_RS14930	COG0582	viral genome integration into host DNA
KS08_RS14945	COG0628	permease
KS08_RS14950	COG0673	inositol 2-dehydrogenase activity
KS08_RS14955	COG0693	protein deglycase activity
KS08_RS14960	COG0840	transmembrane signaling receptor activity
KS08_RS14965	COG0840	transmembrane signaling receptor activity
KS08_RS14970	COG0840	transmembrane signaling receptor activity
KS08_RS14975	COG0840	transmembrane signaling receptor activity
KS08_RS14990	COG2070	2-Nitropropane dioxygenase
KS08_RS14995	COG0366	Alpha amylase catalytic
KS08_RS15000	COG1253	flavin adenine dinucleotide binding
KS08_RS15005	COG2738	Putative neutral zinc metallopeptidase
KS08_RS15020	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KS08_RS15040	COG1979	alcohol dehydrogenase
KS08_RS15045	COG1979	alcohol dehydrogenase
KS08_RS15050	COG2155	Conserved Protein
KS08_RS15055	COG1098	S1 RNA binding domain
KS08_RS15060	COG0436	Aminotransferase
KS08_RS15065	COG1522	sequence-specific DNA binding
KS08_RS15070	COG2267	carboxylic ester hydrolase activity
KS08_RS15080	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KS08_RS15085	COG2205	protein histidine kinase activity
KS08_RS15095	COG5018	Exonuclease
KS08_RS15100	COG2814	Major facilitator Superfamily
KS08_RS15105	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KS08_RS15110	COG3011	Protein conserved in bacteria
KS08_RS15120	COG3290	protein histidine kinase activity
KS08_RS15125	COG4565	transcriptional regulatory protein
KS08_RS15130	COG1744	ABC transporter substrate-binding protein PnrA-like
KS08_RS15135	COG3845	ABC transporter
KS08_RS15140	COG4603	Belongs to the binding-protein-dependent transport system permease family
KS08_RS15145	COG1079	Belongs to the binding-protein-dependent transport system permease family
KS08_RS15155	COG2111	Na H antiporter
KS08_RS15155	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KS08_RS15160	COG2111	Na H antiporter
KS08_RS15165	COG1006	Multisubunit Na H antiporter MnhC subunit
KS08_RS15170	COG0651	ATP synthesis coupled electron transport
KS08_RS15175	COG1863	multisubunit Na H antiporter MnhE subunit
KS08_RS15180	COG2212	antiporter activity
KS08_RS15185	COG1320	monovalent cation:proton antiporter activity
KS08_RS15190	COG2050	protein possibly involved in aromatic compounds catabolism
KS08_RS15195	COG2197	response regulator
KS08_RS15200	COG4585	Histidine kinase
KS08_RS15210	COG0142	geranyltranstransferase activity
KS08_RS15225	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KS08_RS15230	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KS08_RS15235	COG1335	isochorismatase
KS08_RS15240	COG5506	Protein of unknown function (DUF1694)
KS08_RS15255	COG0628	permease
KS08_RS15265	COG1418	mRNA catabolic process
KS08_RS15270	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_RS15280	COG1511	domain protein
KS08_RS15285	COG0433	COG0433 Predicted ATPase
KS08_RS15285	COG1674	ftsk spoiiie
KS08_RS15290	COG4499	WXG100 protein secretion system (Wss), protein YukC
KS08_RS15295	COG5417	Belongs to the EsaB family
KS08_RS15300	COG4842	Belongs to the WXG100 family
KS08_RS15305	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KS08_RS15305	COG2508	Transcriptional regulator
KS08_RS15310	COG0686	Belongs to the AlaDH PNT family
KS08_RS15315	COG5634	Uncharacterized conserved protein (DUF2278)
KS08_RS15320	COG3251	PFAM MbtH domain protein
KS08_RS15325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KS08_RS15330	COG3433	isochorismatase activity
KS08_RS15330	COG1535	isochorismatase
KS08_RS15335	COG1021	2,3-dihydroxybenzoate-AMP ligase
KS08_RS15340	COG1169	isochorismate synthase
KS08_RS15345	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_RS15350	COG2819	hydrolase of the alpha beta superfamily
KS08_RS15355	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KS08_RS15360	COG1268	BioY protein
KS08_RS15365	COG2056	Na+-H+ antiporter family
KS08_RS15375	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KS08_RS15380	COG3584	3D domain protein
KS08_RS15390	COG1252	NADH dehydrogenase
KS08_RS15415	COG1131	(ABC) transporter
KS08_RS15445	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
KS08_RS15465	COG5632	N-Acetylmuramoyl-L-alanine amidase
KS08_RS15465	COG1388	LysM domain
KS08_RS15465	COG3409	Peptidoglycan-binding domain 1 protein
KS08_RS15490	COG5434	Belongs to the glycosyl hydrolase 28 family
KS08_RS15500	COG1705	Flagellar rod assembly protein muramidase FlgJ
KS08_RS15585	COG0582	viral genome integration into host DNA
KS08_RS15690	COG4974	Belongs to the 'phage' integrase family
KS08_RS15695	COG0316	Belongs to the HesB IscA family
KS08_RS15705	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KS08_RS15715	COG1252	NADH dehydrogenase
KS08_RS15720	COG4837	Protein of unknown function (DUF1462)
KS08_RS15725	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KS08_RS15730	COG4946	Tricorn protease homolog
KS08_RS15730	COG1506	peptidase
KS08_RS15730	COG0823	Involved in the tonB-independent uptake of proteins
KS08_RS15740	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KS08_RS15745	COG0460	homoserine dehydrogenase
KS08_RS15750	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KS08_RS15755	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KS08_RS15760	COG0647	UMP catabolic process
KS08_RS15765	COG2445	Protein of unknown function DUF86
KS08_RS15770	COG4470	Protein conserved in bacteria
KS08_RS15780	COG0739	heme binding
KS08_RS15790	COG0737	Belongs to the 5'-nucleotidase family
KS08_RS15795	COG0730	response to heat
KS08_RS15800	COG1801	Protein of unknown function DUF72
KS08_RS15815	COG2508	Transcriptional regulator
KS08_RS15825	COG2814	Major facilitator Superfamily
KS08_RS15830	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KS08_RS15835	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KS08_RS15840	COG2356	endonuclease I
KS08_RS15845	COG3842	ATPase activity
KS08_RS15850	COG2188	Transcriptional regulator
KS08_RS15855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KS08_RS15860	COG0395	ABC-type sugar transport system, permease component
KS08_RS15865	COG1175	transmembrane transport
KS08_RS15870	COG1653	transport
KS08_RS15875	COG2222	sugar isomerase
KS08_RS15880	COG0789	Transcriptional regulator
KS08_RS15905	COG0322	excinuclease ABC activity
KS08_RS15910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KS08_RS15925	COG3409	Peptidoglycan-binding domain 1 protein
KS08_RS15930	COG0719	Fe-S assembly protein
KS08_RS15935	COG0822	iron-sulfur transferase activity
KS08_RS15940	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KS08_RS15945	COG0719	Fe-S assembly protein
KS08_RS15950	COG0396	ATPase activity
KS08_RS15955	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KS08_RS15960	COG1464	Belongs to the NlpA lipoprotein family
KS08_RS15965	COG2011	ABC-type metal ion transport system permease component
KS08_RS15970	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KS08_RS15980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KS08_RS15985	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KS08_RS16000	COG1393	Belongs to the ArsC family
KS08_RS16005	COG1960	acyl-CoA dehydrogenase activity
KS08_RS16010	COG0183	Belongs to the thiolase family
KS08_RS16015	COG1024	Enoyl-CoA hydratase
KS08_RS16015	COG1250	3-hydroxyacyl-CoA dehydrogenase
KS08_RS16030	COG5577	PFAM Coat F domain
KS08_RS16035	COG1846	Transcriptional regulator
KS08_RS16040	COG0477	Major facilitator Superfamily
KS08_RS16065	COG1120	ATPase activity
KS08_RS16080	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_RS16085	COG0783	Belongs to the Dps family
KS08_RS16090	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KS08_RS16095	COG0745	RESPONSE REGULATOR receiver
KS08_RS16100	COG2205	protein histidine kinase activity
KS08_RS16100	COG2770	Histidine kinase
KS08_RS16105	COG1309	transcriptional regulator
KS08_RS16110	COG0114	fumarate hydratase activity
KS08_RS16120	COG0697	spore germination
KS08_RS16125	COG0814	amino acid
KS08_RS16135	COG2197	response regulator
KS08_RS16140	COG4585	Histidine kinase
KS08_RS16145	COG4758	membrane
KS08_RS16150	COG3595	metallopeptidase activity
KS08_RS16155	COG1842	Phage shock protein A
KS08_RS16160	COG4758	membrane
KS08_RS16165	COG2814	Major facilitator Superfamily
KS08_RS16170	COG2096	Adenosyltransferase
KS08_RS16175	COG1120	ATPase activity
KS08_RS16180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KS08_RS16185	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KS08_RS16190	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_RS16195	COG3386	PFAM SMP-30 Gluconolaconase
KS08_RS16200	COG2205	protein histidine kinase activity
KS08_RS16205	COG0745	RESPONSE REGULATOR receiver
KS08_RS16215	COG1191	sigma factor activity
KS08_RS16220	COG2140	Oxalate decarboxylase
KS08_RS16230	COG1120	ATPase activity
KS08_RS16235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KS08_RS16240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KS08_RS16245	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KS08_RS16250	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KS08_RS16255	COG0531	amino acid
KS08_RS16265	COG1988	membrane-bound metal-dependent
KS08_RS16270	COG1368	sulfuric ester hydrolase activity
KS08_RS16275	COG1910	domain protein
KS08_RS16280	COG0725	ABC transporter, periplasmic molybdate-binding protein
KS08_RS16285	COG4149	molybdate abc transporter
KS08_RS16290	COG2197	response regulator
KS08_RS16300	COG1131	(ABC) transporter
KS08_RS16310	COG0842	Transport permease protein
KS08_RS16315	COG0656	L-ascorbic acid biosynthetic process
KS08_RS16335	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KS08_RS16340	COG3973	AAA domain
KS08_RS16345	COG2860	membrane
KS08_RS16355	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KS08_RS16360	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KS08_RS16365	COG2217	Heavy metal translocating P-type atpase
KS08_RS16370	COG2217	Heavy metal translocating P-type atpase
KS08_RS16375	COG2608	mercury ion transmembrane transporter activity
KS08_RS16380	COG1937	Protein conserved in bacteria
KS08_RS16385	COG0673	inositol 2-dehydrogenase activity
KS08_RS16395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KS08_RS16400	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KS08_RS16405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KS08_RS16410	COG1126	abc transporter atp-binding protein
KS08_RS16415	COG0765	amino acid transport
KS08_RS16420	COG0765	amino acid transport
KS08_RS16425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KS08_RS16430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KS08_RS16435	COG0454	-acetyltransferase
KS08_RS16440	COG0583	DNA-binding transcription factor activity
KS08_RS16445	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_RS16450	COG2732	(Barnase) inhibitor
KS08_RS16460	COG0557	exoribonuclease II activity
KS08_RS16465	COG1647	Serine aminopeptidase, S33
KS08_RS16470	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KS08_RS16475	COG1476	TRANSCRIPTIONal
KS08_RS16480	COG1396	sequence-specific DNA binding
KS08_RS16485	COG1396	sequence-specific DNA binding
KS08_RS16490	COG1733	regulation of RNA biosynthetic process
KS08_RS16515	COG1131	(ABC) transporter
KS08_RS16520	COG1174	glycine betaine transport
KS08_RS16525	COG1732	Glycine betaine
KS08_RS16530	COG1174	glycine betaine transport
KS08_RS16535	COG0517	IMP dehydrogenase activity
KS08_RS16535	COG1125	glycine betaine transport
KS08_RS16540	COG1510	regulation of RNA biosynthetic process
KS08_RS16545	COG1174	glycine betaine transport
KS08_RS16550	COG1732	Glycine betaine
KS08_RS16555	COG1174	glycine betaine transport
KS08_RS16560	COG0517	IMP dehydrogenase activity
KS08_RS16560	COG1125	glycine betaine transport
KS08_RS16565	COG1510	regulation of RNA biosynthetic process
KS08_RS16570	COG2095	MarC family integral membrane protein
KS08_RS16575	COG3064	Membrane
KS08_RS16585	COG0456	acetyltransferase
KS08_RS16600	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KS08_RS16620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KS08_RS16625	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KS08_RS16635	COG2234	aminopeptidase activity
KS08_RS16655	COG0126	phosphoglycerate kinase activity
KS08_RS16665	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KS08_RS16670	COG2390	Transcriptional regulator
KS08_RS16675	COG2814	Major facilitator Superfamily
KS08_RS16680	COG1609	Transcriptional regulator
KS08_RS16685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KS08_RS16690	COG0583	DNA-binding transcription factor activity
KS08_RS16695	COG0697	spore germination
KS08_RS16700	COG1113	amino acid transport
KS08_RS16705	COG1737	Transcriptional regulator
KS08_RS16710	COG1070	Carbohydrate kinase
KS08_RS16735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KS08_RS16740	COG2186	Transcriptional regulator
KS08_RS16745	COG1620	l-lactate permease
KS08_RS16750	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KS08_RS16760	COG5039	Polysaccharide pyruvyl transferase
KS08_RS16765	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KS08_RS16770	COG0110	maltose O-acetyltransferase activity
KS08_RS16775	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KS08_RS16780	COG2244	polysaccharide biosynthetic process
KS08_RS16785	COG1216	Glycosyl transferase, family 2
KS08_RS16790	COG5039	Polysaccharide pyruvyl transferase
KS08_RS16795	COG1216	Glycosyl transferase, family 2
KS08_RS16805	COG0438	transferase activity, transferring glycosyl groups
KS08_RS16810	COG1215	transferase activity, transferring glycosyl groups
KS08_RS16815	COG0438	transferase activity, transferring glycosyl groups
KS08_RS16820	COG1086	Polysaccharide biosynthesis protein
KS08_RS16825	COG0489	protein tyrosine kinase activity
KS08_RS16830	COG3944	biosynthesis protein
KS08_RS16835	COG1396	sequence-specific DNA binding
KS08_RS16840	COG2272	Belongs to the type-B carboxylesterase lipase family
KS08_RS16850	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KS08_RS16865	COG2364	Membrane
KS08_RS16870	COG0456	acetyltransferase
KS08_RS16875	COG3479	Phenolic acid decarboxylase
KS08_RS16920	COG2223	nitrite transmembrane transporter activity
KS08_RS16925	COG1609	Transcriptional regulator
KS08_RS16935	COG0583	DNA-binding transcription factor activity
KS08_RS16940	COG2828	Protein conserved in bacteria
KS08_RS16945	COG2814	Major facilitator Superfamily
KS08_RS16945	COG0477	Major facilitator Superfamily
KS08_RS16955	COG1611	Belongs to the LOG family
KS08_RS16960	COG1694	Mazg nucleotide pyrophosphohydrolase
KS08_RS16965	COG0659	secondary active sulfate transmembrane transporter activity
KS08_RS16970	COG0288	reversible hydration of carbon dioxide
KS08_RS16980	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KS08_RS16985	COG4290	ribonuclease
KS08_RS16990	COG2162	N-hydroxyarylamine O-acetyltransferase activity
KS08_RS16995	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KS08_RS17005	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KS08_RS17015	COG1051	belongs to the nudix hydrolase family
KS08_RS17020	COG0492	ferredoxin-NADP+ reductase activity
KS08_RS17025	COG0791	NLP P60 protein
KS08_RS17025	COG3883	PFAM NLP P60 protein
KS08_RS17030	COG0457	Tetratricopeptide repeat
KS08_RS17035	COG5002	protein histidine kinase activity
KS08_RS17040	COG0745	RESPONSE REGULATOR receiver
KS08_RS17045	COG1132	(ABC) transporter
KS08_RS17050	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KS08_RS17050	COG0140	phosphoribosyl-ATP diphosphatase activity
KS08_RS17075	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KS08_RS17090	COG4990	cell redox homeostasis
KS08_RS17095	COG0110	maltose O-acetyltransferase activity
KS08_RS17115	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KS08_RS17125	COG2188	Transcriptional regulator
KS08_RS17130	COG1309	transcriptional regulator
KS08_RS17135	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KS08_RS17140	COG1950	PFAM Membrane protein of
KS08_RS17145	COG1983	PspC domain protein
KS08_RS17150	COG3595	metallopeptidase activity
KS08_RS17165	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KS08_RS17175	COG4897	Protein conserved in bacteria
KS08_RS17180	COG0574	Belongs to the PEP-utilizing enzyme family
KS08_RS17180	COG3848	Pyruvate phosphate dikinase
KS08_RS17185	COG1309	transcriptional regulator
KS08_RS17190	COG2814	Major facilitator Superfamily
KS08_RS17205	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KS08_RS17215	COG0793	Belongs to the peptidase S41A family
KS08_RS17215	COG3409	Peptidoglycan-binding domain 1 protein
KS08_RS17220	COG3420	alginic acid biosynthetic process
KS08_RS17225	COG2177	Part of the ABC transporter FtsEX involved in
KS08_RS17230	COG2884	Cell division ATP-binding protein ftsE
KS08_RS17235	COG2010	Cytochrome c
KS08_RS17240	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KS08_RS17245	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KS08_RS17255	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KS08_RS17270	COG1516	flagellar protein fliS
KS08_RS17275	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KS08_RS17280	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KS08_RS17300	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KS08_RS17305	COG4786	Flagellar basal body rod
KS08_RS17305	COG1256	bacterial-type flagellum assembly
KS08_RS17310	COG3418	PFAM FlgN family protein
KS08_RS17315	COG2747	anti-sigma28 factor FlgM
KS08_RS17325	COG1040	competence protein
KS08_RS17335	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KS08_RS17340	COG1307	EDD domain protein, DegV family
KS08_RS17345	COG2197	response regulator
KS08_RS17350	COG4585	Histidine kinase
KS08_RS17355	COG1739	Uncharacterized protein family UPF0029
KS08_RS17360	COG1316	TRANSCRIPTIONal
KS08_RS17365	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KS08_RS17370	COG0438	transferase activity, transferring glycosyl groups
KS08_RS17375	COG1215	transferase activity, transferring glycosyl groups
KS08_RS17380	COG3206	protein involved in exopolysaccharide biosynthesis
KS08_RS17385	COG3307	-O-antigen
KS08_RS17390	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KS08_RS17395	COG0297	glycogen (starch) synthase activity
KS08_RS17395	COG0438	transferase activity, transferring glycosyl groups
KS08_RS17400	COG2244	polysaccharide biosynthetic process
KS08_RS17410	COG2247	cell wall binding repeat
KS08_RS17410	COG0860	N-Acetylmuramoyl-L-alanine amidase
KS08_RS17415	COG2385	sporulation resulting in formation of a cellular spore
KS08_RS17415	COG2247	cell wall binding repeat
KS08_RS17425	COG1316	TRANSCRIPTIONal
KS08_RS17430	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KS08_RS17435	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KS08_RS17440	COG1134	teichoic acid transport
KS08_RS17445	COG1682	transport, permease protein
KS08_RS17450	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KS08_RS17455	COG0438	transferase activity, transferring glycosyl groups
KS08_RS17460	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KS08_RS17465	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
KS08_RS17470	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KS08_RS17475	COG4193	domain, Protein
KS08_RS17480	COG1482	cell wall glycoprotein biosynthetic process
KS08_RS17485	COG0697	spore germination
KS08_RS17490	COG0814	amino acid
KS08_RS17500	COG1215	transferase activity, transferring glycosyl groups
KS08_RS17505	COG2814	Major facilitator Superfamily
KS08_RS17510	COG1316	TRANSCRIPTIONal
KS08_RS17515	COG0561	phosphatase activity
KS08_RS17520	COG2433	Pfam Transposase IS66
KS08_RS17525	COG0791	NLP P60 protein
KS08_RS17530	COG2843	Capsule synthesis protein
KS08_RS17540	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KS08_RS17545	COG0697	spore germination
KS08_RS17550	COG0814	amino acid
KS08_RS17560	COG1609	Transcriptional regulator
KS08_RS17565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KS08_RS17575	COG1129	ABC transporter
KS08_RS17580	COG1172	Belongs to the binding-protein-dependent transport system permease family
KS08_RS17585	COG1879	ABC-type sugar transport system periplasmic component
KS08_RS17590	COG3103	Sh3 type 3 domain protein
KS08_RS17595	COG2249	NAD(P)H dehydrogenase (quinone) activity
KS08_RS17600	COG3527	Alpha-acetolactate decarboxylase
KS08_RS17605	COG0028	Belongs to the TPP enzyme family
KS08_RS17610	COG0583	DNA-binding transcription factor activity
KS08_RS17615	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KS08_RS17630	COG5337	Spore coat protein CotH
KS08_RS17640	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KS08_RS17650	COG0405	Gamma-glutamyltransferase
KS08_RS17655	COG1522	sequence-specific DNA binding
KS08_RS17660	COG2059	Chromate
KS08_RS17665	COG2059	Chromate
KS08_RS17695	COG5444	nuclease activity
KS08_RS17710	COG3878	Protein conserved in bacteria
KS08_RS17715	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KS08_RS17720	COG4464	protein tyrosine phosphatase activity
KS08_RS17725	COG0489	protein tyrosine kinase activity
KS08_RS17730	COG3944	biosynthesis protein
KS08_RS17740	COG4715	Zinc finger, swim domain protein
KS08_RS17745	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KS08_RS17750	COG0561	phosphatase activity
KS08_RS17755	COG1349	DNA-binding transcription factor activity
KS08_RS17760	COG0629	single-stranded DNA binding
KS08_RS17785	COG0457	Tetratricopeptide repeat
KS08_RS17790	COG4786	Flagellar basal body rod
KS08_RS17795	COG4786	Flagellar basal body rod
KS08_RS17800	COG1077	Cell shape determining protein MreB Mrl
KS08_RS17805	COG1609	Transcriptional regulator
KS08_RS17810	COG1846	Transcriptional regulator
KS08_RS17815	COG2814	Major facilitator Superfamily
KS08_RS17820	COG1953	Uracil, thiamine, allantoin
KS08_RS17830	COG1335	isochorismatase
KS08_RS17835	COG0004	ammonium transporteR
KS08_RS17840	COG0347	Belongs to the P(II) protein family
KS08_RS17845	COG0772	Belongs to the SEDS family
KS08_RS17850	COG0671	phosphoesterase, PA-phosphatase related
KS08_RS17860	COG0739	heme binding
KS08_RS17865	COG1247	-acetyltransferase
KS08_RS17880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KS08_RS17895	COG2910	NAD(P)H-binding
KS08_RS17900	COG1959	2 iron, 2 sulfur cluster binding
KS08_RS17915	COG0831	urea catabolic process
KS08_RS17920	COG3237	CsbD-like
KS08_RS17925	COG1994	Peptidase M50
KS08_RS17930	COG0457	Tetratricopeptide repeat
KS08_RS17940	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KS08_RS17945	COG2304	oxidoreductase activity
KS08_RS17950	COG2304	oxidoreductase activity
KS08_RS17955	COG2385	sporulation resulting in formation of a cellular spore
KS08_RS17960	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KS08_RS17970	COG4836	Membrane
KS08_RS18040	COG0698	ribose 5-phosphate isomerase
KS08_RS18045	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KS08_RS18055	COG0009	L-threonylcarbamoyladenylate synthase
KS08_RS18060	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KS08_RS18080	COG2890	protein-(glutamine-N5) methyltransferase activity
KS08_RS18085	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KS08_RS18090	COG0346	lactoylglutathione lyase activity
KS08_RS18095	COG0789	Transcriptional regulator
KS08_RS18100	COG0679	Auxin Efflux Carrier
KS08_RS18105	COG0281	malic enzyme
KS08_RS18120	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KS08_RS18125	COG1494	fructose-1,6-bisphosphatase
KS08_RS18130	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KS08_RS18140	COG0191	fructose-bisphosphate aldolase activity
KS08_RS18145	COG2204	response regulator
KS08_RS18150	COG4821	SIS domain
KS08_RS18165	COG0247	lactate metabolic process
KS08_RS18165	COG2181	nitrate reductase activity
KS08_RS18170	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KS08_RS18185	COG1132	(ABC) transporter
KS08_RS18190	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KS08_RS18195	COG2181	nitrate reductase activity
KS08_RS18200	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KS08_RS18205	COG1140	nitrate reductase beta subunit
KS08_RS18210	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KS08_RS18215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KS08_RS18225	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KS08_RS18230	COG2223	nitrite transmembrane transporter activity
KS08_RS18240	COG4506	Protein conserved in bacteria
KS08_RS18250	COG3391	amine dehydrogenase activity
KS08_RS18255	COG0457	Tetratricopeptide repeat
KS08_RS18265	COG0010	Belongs to the arginase family
KS08_RS18270	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KS08_RS18275	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KS08_RS18290	COG1994	Peptidase M50
KS08_RS18295	COG1942	4-Oxalocrotonate Tautomerase
KS08_RS18300	COG1846	Transcriptional regulator
KS08_RS18305	COG0531	amino acid
KS08_RS18310	COG3465	dGTPase activity
KS08_RS18315	COG1078	dGTPase activity
KS08_RS18330	COG1695	Transcriptional regulator
KS08_RS18345	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KS08_RS18375	COG0583	DNA-binding transcription factor activity
KS08_RS18380	COG2855	membrane
KS08_RS18385	COG0280	phosphate acetyltransferase
KS08_RS18395	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_RS18400	COG0436	Aminotransferase
KS08_RS18410	COG0151	Belongs to the GarS family
KS08_RS18420	COG1917	Cupin 2, conserved barrel domain protein
KS08_RS18425	COG0077	Prephenate dehydratase
KS08_RS18430	COG2814	Major facilitator Superfamily
KS08_RS18435	COG2814	Major facilitator Superfamily
KS08_RS18440	COG0833	amino acid
KS08_RS18445	COG4187	Peptidase family M20/M25/M40
KS08_RS18450	COG1012	belongs to the aldehyde dehydrogenase family
KS08_RS18455	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KS08_RS18465	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
KS08_RS18470	COG1091	dTDP-4-dehydrorhamnose reductase activity
KS08_RS18475	COG1088	dTDP-glucose 4,6-dehydratase activity
KS08_RS18480	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KS08_RS18485	COG3980	spore coat polysaccharide biosynthesis protein
KS08_RS18490	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
KS08_RS18495	COG2089	acid synthase
KS08_RS18500	COG0456	acetyltransferase
KS08_RS18505	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KS08_RS18510	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KS08_RS18515	COG0463	Glycosyl transferase, family 2
KS08_RS18525	COG2363	Small membrane protein
KS08_RS18530	COG2233	PERMEase
KS08_RS18545	COG1216	Glycosyl transferase, family 2
KS08_RS18555	COG0351	phosphomethylpyrimidine kinase
KS08_RS18565	COG1621	beta-fructofuranosidase activity
KS08_RS18570	COG1263	PTS System
KS08_RS18570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KS08_RS18575	COG3711	transcriptional antiterminator
KS08_RS18585	COG1404	Belongs to the peptidase S8 family
KS08_RS18590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KS08_RS18595	COG2378	regulation of single-species biofilm formation
KS08_RS18615	COG0778	Nitroreductase
KS08_RS18620	COG0772	Belongs to the SEDS family
KS08_RS18625	COG0454	-acetyltransferase
KS08_RS18645	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KS08_RS18650	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KS08_RS18655	COG2261	transglycosylase associated protein
KS08_RS18660	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
KS08_RS18665	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KS08_RS18670	COG2246	polysaccharide biosynthetic process
KS08_RS18675	COG1309	transcriptional regulator
KS08_RS18695	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KS08_RS18700	COG2837	iron assimilation
KS08_RS18705	COG2822	iron ion transport
KS08_RS18710	COG0672	)-iron permease
KS08_RS18725	COG0583	DNA-binding transcription factor activity
KS08_RS18735	COG1346	cytolysis
KS08_RS18740	COG4895	conserved protein (DUF2196)
KS08_RS18745	COG0789	Transcriptional regulator
KS08_RS18750	COG5504	Zn-dependent protease
KS08_RS18755	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KS08_RS18760	COG0346	lactoylglutathione lyase activity
KS08_RS18765	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KS08_RS18770	COG1404	Belongs to the peptidase S8 family
KS08_RS18775	COG1442	glycosyl transferase family 8
KS08_RS18780	COG2357	RelA SpoT domain protein
KS08_RS18785	COG1575	Belongs to the MenA family. Type 1 subfamily
KS08_RS18805	COG0697	spore germination
KS08_RS18810	COG0589	response to stress
KS08_RS18815	COG2723	6-phospho-beta-galactosidase activity
KS08_RS18820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KS08_RS18820	COG2190	(PTS) system
KS08_RS18820	COG1263	PTS System
KS08_RS18835	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KS08_RS18860	COG3507	Belongs to the glycosyl hydrolase 43 family
KS08_RS18885	COG0010	Belongs to the arginase family
KS08_RS18890	COG0833	amino acid
KS08_RS18895	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KS08_RS18900	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KS08_RS18915	COG0561	phosphatase activity
KS08_RS18945	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KS08_RS18950	COG5294	Protein conserved in bacteria
KS08_RS18955	COG0577	efflux transmembrane transporter activity
KS08_RS18960	COG1136	(ABC) transporter
KS08_RS18965	COG2205	protein histidine kinase activity
KS08_RS18970	COG0745	RESPONSE REGULATOR receiver
KS08_RS18985	COG1082	Xylose isomerase domain protein TIM barrel
KS08_RS18995	COG2814	Major facilitator Superfamily
KS08_RS19025	COG1349	DNA-binding transcription factor activity
KS08_RS19030	COG0667	Aldo Keto reductase
KS08_RS19035	COG2814	Major facilitator Superfamily
KS08_RS19045	COG1028	Short-chain dehydrogenase reductase Sdr
KS08_RS19050	COG2197	response regulator
KS08_RS19055	COG4585	Histidine kinase
KS08_RS19060	COG3239	Fatty acid desaturase
KS08_RS19065	COG1309	transcriptional regulator
KS08_RS19070	COG1012	belongs to the aldehyde dehydrogenase family
KS08_RS19075	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KS08_RS19085	COG0640	Transcriptional regulator
KS08_RS19090	COG2814	Major facilitator Superfamily
KS08_RS19095	COG1714	RDD family
KS08_RS19105	COG0450	alkyl hydroperoxide reductase
KS08_RS19110	COG3634	alkyl hydroperoxide reductase activity
KS08_RS19120	COG1113	amino acid transport
KS08_RS19150	COG2080	2 iron, 2 sulfur cluster binding
KS08_RS19160	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KS08_RS19165	COG2068	MobA-Related Protein
KS08_RS19170	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KS08_RS19215	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
KS08_RS19220	COG0667	Aldo Keto reductase
KS08_RS19225	COG0456	acetyltransferase
KS08_RS19230	COG0457	Tetratricopeptide repeat
KS08_RS19235	COG0010	Belongs to the arginase family
KS08_RS19240	COG0833	amino acid
KS08_RS19245	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KS08_RS19250	COG5658	integral membrane protein
KS08_RS19255	COG0640	Transcriptional regulator
KS08_RS19260	COG3829	transcription factor binding
KS08_RS19275	COG3850	Histidine kinase
KS08_RS19275	COG5002	protein histidine kinase activity
KS08_RS19280	COG0745	RESPONSE REGULATOR receiver
KS08_RS19290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KS08_RS19295	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KS08_RS19300	COG4853	Protein conserved in bacteria
KS08_RS19305	COG4863	YycH protein
KS08_RS19310	COG5002	protein histidine kinase activity
KS08_RS19315	COG0745	RESPONSE REGULATOR receiver
KS08_RS19350	COG0346	lactoylglutathione lyase activity
KS08_RS19355	COG0305	Participates in initiation and elongation during chromosome replication
KS08_RS19385	COG0438	transferase activity, transferring glycosyl groups
KS08_RS19405	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KS08_RS19410	COG4241	membrane
KS08_RS19420	COG5577	PFAM Coat F domain
KS08_RS19425	COG1733	regulation of RNA biosynthetic process
KS08_RS19435	COG0697	spore germination
KS08_RS19440	COG1621	beta-fructofuranosidase activity
KS08_RS19445	COG1621	beta-fructofuranosidase activity
KS08_RS19455	COG2318	DinB family
KS08_RS19460	COG2211	Major facilitator Superfamily
KS08_RS19470	COG0778	Nitroreductase
KS08_RS19475	COG1846	Transcriptional regulator
KS08_RS19480	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KS08_RS19485	COG1846	Transcriptional regulator
KS08_RS19490	COG2153	protein acetylation
KS08_RS19500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KS08_RS19505	COG0697	spore germination
KS08_RS19510	COG1331	Highly conserved protein containing a thioredoxin domain
KS08_RS19520	COG1331	Highly conserved protein containing a thioredoxin domain
KS08_RS19525	COG1266	CAAX protease self-immunity
KS08_RS19530	COG0477	Major facilitator Superfamily
KS08_RS19530	COG2814	Major facilitator Superfamily
KS08_RS19535	COG0346	lactoylglutathione lyase activity
KS08_RS19540	COG1609	Transcriptional regulator
KS08_RS19545	COG0708	Exodeoxyribonuclease III
KS08_RS19550	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KS08_RS19555	COG2169	Transcriptional regulator
KS08_RS19565	COG0629	single-stranded DNA binding
KS08_RS19575	COG0012	GTP binding
KS08_RS19580	COG0243	molybdopterin cofactor binding
KS08_RS19585	COG4481	Protein conserved in bacteria
KS08_RS19590	COG3949	Membrane
KS08_RS19605	COG1475	DNA binding
KS08_RS19610	COG1192	Involved in chromosome partitioning
KS08_RS19635	COG1847	R3H domain protein
KS08_RS19640	COG0706	membrane insertase activity
KS08_RS19655	COG2946	Replication initiation factor