locus-tag	class	description
BS21228_RS00060	COG1388	LysM domain
BS21228_RS00060	COG3409	Peptidoglycan-binding domain 1 protein
BS21228_RS00060	COG5632	N-Acetylmuramoyl-L-alanine amidase
BS21228_RS00070	COG5444	nuclease activity
BS21228_RS00110	COG4282	regulation of fungal-type cell wall biogenesis
BS21228_RS00135	COG3328	transposase activity
BS21228_RS00150	COG3655	Transcriptional regulator
BS21228_RS00175	COG0135	phosphoribosylanthranilate isomerase activity
BS21228_RS00180	COG2211	Major facilitator Superfamily
BS21228_RS00195	COG3507	Belongs to the glycosyl hydrolase 43 family
BS21228_RS00200	COG1940	carbohydrate kinase activity
BS21228_RS00205	COG2115	Belongs to the xylose isomerase family
BS21228_RS00210	COG1070	Carbohydrate kinase
BS21228_RS00225	COG3328	transposase activity
BS21228_RS00230	COG1525	nuclease
BS21228_RS00235	COG2814	Major facilitator Superfamily
BS21228_RS00240	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BS21228_RS00255	COG0756	dUTP diphosphatase activity
BS21228_RS00295	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BS21228_RS00310	COG3832	glyoxalase III activity
BS21228_RS00355	COG4195	phage-related replication protein
BS21228_RS00365	COG0346	lactoylglutathione lyase activity
BS21228_RS00375	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BS21228_RS00380	COG1388	LysM domain
BS21228_RS00385	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BS21228_RS00390	COG4224	UPF0291 protein
BS21228_RS00395	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BS21228_RS00405	COG3763	UPF0154 protein
BS21228_RS00415	COG0785	Cytochrome C biogenesis protein
BS21228_RS00420	COG2201	protein-glutamate methylesterase activity
BS21228_RS00425	COG4846	Membrane protein involved in cytochrome C biogenesis
BS21228_RS00435	COG0071	Belongs to the small heat shock protein (HSP20) family
BS21228_RS00450	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BS21228_RS00455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS21228_RS00475	COG0824	Thioesterase
BS21228_RS00485	COG4841	protein insertion into membrane
BS21228_RS00490	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BS21228_RS00495	COG1832	CoA-binding protein
BS21228_RS00500	COG0187	DNA topoisomerase II activity
BS21228_RS00505	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BS21228_RS00515	COG1115	amino acid carrier protein
BS21228_RS00520	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BS21228_RS00530	COG5520	Belongs to the glycosyl hydrolase 30 family
BS21228_RS00540	COG2246	polysaccharide biosynthetic process
BS21228_RS00545	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BS21228_RS00550	COG0586	Pfam SNARE associated Golgi protein
BS21228_RS00555	COG2404	hydrolase activity, acting on ester bonds
BS21228_RS00560	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BS21228_RS00565	COG1024	Enoyl-CoA hydratase
BS21228_RS00570	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BS21228_RS00575	COG0511	ligase activity, forming carbon-carbon bonds
BS21228_RS00580	COG0439	Biotin carboxylase
BS21228_RS00585	COG0318	PFAM AMP-dependent synthetase and ligase
BS21228_RS00590	COG1960	acyl-CoA dehydrogenase activity
BS21228_RS00600	COG1649	PFAM Uncharacterised BCR, COG1649
BS21228_RS00615	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BS21228_RS00620	COG2027	D-alanyl-D-alanine carboxypeptidase
BS21228_RS00625	COG2017	converts alpha-aldose to the beta-anomer
BS21228_RS00630	COG0534	Mate efflux family protein
BS21228_RS00650	COG0582	viral genome integration into host DNA
BS21228_RS00655	COG0166	Belongs to the GPI family
BS21228_RS00660	COG0405	Gamma-glutamyltransferase
BS21228_RS00665	COG0583	DNA-binding transcription factor activity
BS21228_RS00670	COG0604	alcohol dehydrogenase
BS21228_RS00675	COG0493	'glutamate synthase
BS21228_RS00680	COG0069	glutamate synthase activity
BS21228_RS00680	COG0070	glutamate synthase
BS21228_RS00680	COG0067	glutamate synthase
BS21228_RS00685	COG0583	DNA-binding transcription factor activity
BS21228_RS00715	COG0300	oxidoreductase activity
BS21228_RS00720	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BS21228_RS00730	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS21228_RS00745	COG1131	(ABC) transporter
BS21228_RS00755	COG2814	Major facilitator Superfamily
BS21228_RS00765	COG3328	transposase activity
BS21228_RS00805	COG3328	transposase activity
BS21228_RS00865	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BS21228_RS00870	COG2226	methyltransferase
BS21228_RS00875	COG2211	Major facilitator Superfamily
BS21228_RS00880	COG3328	transposase activity
BS21228_RS00910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS21228_RS00930	COG5444	nuclease activity
BS21228_RS00935	COG4282	regulation of fungal-type cell wall biogenesis
BS21228_RS00940	COG1231	oxidoreductase activity
BS21228_RS00945	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BS21228_RS00950	COG0662	Cupin 2, conserved barrel domain protein
BS21228_RS00950	COG2207	Transcriptional regulator
BS21228_RS00955	COG0456	acetyltransferase
BS21228_RS00960	COG1309	transcriptional regulator
BS21228_RS00965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BS21228_RS00970	COG3708	Transcriptional regulator
BS21228_RS00975	COG2378	regulation of single-species biofilm formation
BS21228_RS00985	COG0640	Transcriptional regulator
BS21228_RS00990	COG0741	lytic transglycosylase activity
BS21228_RS00995	COG2322	membrane
BS21228_RS01010	COG1619	proteins homologs of microcin C7 resistance protein MccF
BS21228_RS01015	COG3239	Fatty acid desaturase
BS21228_RS01020	COG4585	Histidine kinase
BS21228_RS01025	COG2197	response regulator
BS21228_RS01030	COG3584	3D domain protein
BS21228_RS01030	COG1388	LysM domain
BS21228_RS01035	COG0514	ATP-dependent DNA helicase (RecQ)
BS21228_RS01050	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BS21228_RS01055	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BS21228_RS01070	COG0071	Belongs to the small heat shock protein (HSP20) family
BS21228_RS01095	COG1012	belongs to the aldehyde dehydrogenase family
BS21228_RS01100	COG1657	PFAM Prenyltransferase squalene oxidase
BS21228_RS01105	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BS21228_RS01110	COG0733	neurotransmitter:sodium symporter activity
BS21228_RS01115	COG0385	Bile acid
BS21228_RS01120	COG0508	dehydrogenase complex catalyzes the overall conversion of
BS21228_RS01125	COG0567	Dehydrogenase, E1 component
BS21228_RS01130	COG4548	von Willebrand factor, type A
BS21228_RS01135	COG0714	Associated with various cellular activities
BS21228_RS01140	COG2032	superoxide dismutase activity
BS21228_RS01145	COG1388	LysM domain
BS21228_RS01145	COG0791	NLP P60 protein
BS21228_RS01150	COG1819	glycosyl
BS21228_RS01155	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BS21228_RS01160	COG0534	Mate efflux family protein
BS21228_RS01165	COG1366	Belongs to the anti-sigma-factor antagonist family
BS21228_RS01170	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BS21228_RS01175	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BS21228_RS01185	COG2962	Rard protein
BS21228_RS01205	COG1942	4-Oxalocrotonate Tautomerase
BS21228_RS01210	COG1733	regulation of RNA biosynthetic process
BS21228_RS01215	COG0778	Nitroreductase
BS21228_RS01225	COG0400	carboxylic ester hydrolase activity
BS21228_RS01240	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BS21228_RS01245	COG3409	Peptidoglycan-binding domain 1 protein
BS21228_RS01245	COG0793	Belongs to the peptidase S41A family
BS21228_RS01250	COG2226	methyltransferase
BS21228_RS01260	COG1876	peptidase activity
BS21228_RS01265	COG0813	purine-nucleoside phosphorylase activity
BS21228_RS01280	COG0671	phosphoesterase, PA-phosphatase related
BS21228_RS01305	COG4479	Belongs to the UPF0346 family
BS21228_RS01315	COG1509	lysine 2,3-aminomutase activity
BS21228_RS01320	COG0456	acetyltransferase
BS21228_RS01325	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BS21228_RS01330	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BS21228_RS01335	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BS21228_RS01340	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BS21228_RS01350	COG0456	acetyltransferase
BS21228_RS01355	COG0463	Glycosyl transferase, family 2
BS21228_RS01370	COG4641	Protein conserved in bacteria
BS21228_RS01375	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
BS21228_RS01380	COG1086	Polysaccharide biosynthesis protein
BS21228_RS01385	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BS21228_RS01390	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BS21228_RS01395	COG1846	Transcriptional regulator
BS21228_RS01400	COG0534	Mate efflux family protein
BS21228_RS01410	COG4698	Protein conserved in bacteria
BS21228_RS01415	COG2755	lipolytic protein G-D-S-L family
BS21228_RS01420	COG1999	signal sequence binding
BS21228_RS01430	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BS21228_RS01435	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BS21228_RS01440	COG1272	protein, Hemolysin III
BS21228_RS01445	COG0204	Acyl-transferase
BS21228_RS01450	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BS21228_RS01455	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BS21228_RS01465	COG2521	methyltransferase
BS21228_RS01465	COG2136	Putative SAM-dependent methyltransferase
BS21228_RS01475	COG0129	dihydroxy-acid dehydratase activity
BS21228_RS01480	COG1413	lyase activity
BS21228_RS01485	COG1418	mRNA catabolic process
BS21228_RS01490	COG0386	Belongs to the glutathione peroxidase family
BS21228_RS01495	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BS21228_RS01500	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BS21228_RS01505	COG1278	Cold shock
BS21228_RS01525	COG0328	RNA-DNA hybrid ribonuclease activity
BS21228_RS01530	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BS21228_RS01535	COG0328	RNA-DNA hybrid ribonuclease activity
BS21228_RS01545	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BS21228_RS01560	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BS21228_RS01570	COG1755	Isoprenylcysteine carboxyl methyltransferase
BS21228_RS01575	COG3424	synthase
BS21228_RS01580	COG2233	PERMEase
BS21228_RS01585	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BS21228_RS01590	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BS21228_RS01600	COG0800	Aldolase
BS21228_RS01605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BS21228_RS01610	COG1609	Transcriptional regulator
BS21228_RS01615	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BS21228_RS01620	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_RS01625	COG1199	ATP-dependent helicase activity
BS21228_RS01640	COG0116	Belongs to the methyltransferase superfamily
BS21228_RS01655	COG4474	Belongs to the UPF0398 family
BS21228_RS01665	COG3359	exonuclease
BS21228_RS01670	COG1205	dead DEAH box helicase
BS21228_RS01670	COG1111	helicase
BS21228_RS01675	COG2190	(PTS) system
BS21228_RS01680	COG0071	Belongs to the small heat shock protein (HSP20) family
BS21228_RS01715	COG3331	DNA recombination
BS21228_RS01720	COG4499	WXG100 protein secretion system (Wss), protein YukC
BS21228_RS01720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BS21228_RS01730	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BS21228_RS01735	COG3935	DnaD domain protein
BS21228_RS01740	COG0017	Asparaginyl-tRNA synthetase
BS21228_RS01745	COG0436	Aminotransferase
BS21228_RS01750	COG5353	protein conserved in bacteria
BS21228_RS01760	COG1199	ATP-dependent helicase activity
BS21228_RS01760	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BS21228_RS01765	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BS21228_RS01770	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BS21228_RS01775	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BS21228_RS01780	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BS21228_RS01780	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BS21228_RS01785	COG0617	tRNA 3'-terminal CCA addition
BS21228_RS01790	COG0438	transferase activity, transferring glycosyl groups
BS21228_RS01795	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BS21228_RS01800	COG1803	Methylglyoxal synthase
BS21228_RS01805	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BS21228_RS01810	COG1694	Mazg nucleotide pyrophosphohydrolase
BS21228_RS01815	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BS21228_RS01825	COG4347	Protein of unknown function (DUF1405)
BS21228_RS01830	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BS21228_RS01830	COG2010	Cytochrome c
BS21228_RS01835	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BS21228_RS01840	COG0723	plastoquinol--plastocyanin reductase activity
BS21228_RS01850	COG5582	Belongs to the UPF0302 family
BS21228_RS01855	COG0457	Tetratricopeptide repeat
BS21228_RS01860	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BS21228_RS01865	COG0287	Prephenate dehydrogenase
BS21228_RS01880	COG0133	tryptophan synthase activity
BS21228_RS01885	COG0135	phosphoribosylanthranilate isomerase activity
BS21228_RS01895	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BS21228_RS01900	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BS21228_RS01905	COG4401	Chorismate mutase type I
BS21228_RS01910	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BS21228_RS01915	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BS21228_RS01920	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BS21228_RS01925	COG0105	UTP biosynthetic process
BS21228_RS01930	COG0142	geranyltranstransferase activity
BS21228_RS01935	COG2226	methyltransferase
BS21228_RS01940	COG0142	geranyltranstransferase activity
BS21228_RS01950	COG0302	gtp cyclohydrolase
BS21228_RS01955	COG0776	regulation of translation
BS21228_RS01960	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BS21228_RS01975	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BS21228_RS01980	COG1160	GTP binding
BS21228_RS02005	COG1304	FMN binding
BS21228_RS02010	COG0539	negative regulation of cytoplasmic translation
BS21228_RS02015	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BS21228_RS02025	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BS21228_RS02030	COG2959	enzyme of heme biosynthesis
BS21228_RS02035	COG3773	Cell wall hydrolase
BS21228_RS02035	COG3409	Peptidoglycan-binding domain 1 protein
BS21228_RS02040	COG2339	peptidase activity
BS21228_RS02045	COG0492	ferredoxin-NADP+ reductase activity
BS21228_RS02050	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BS21228_RS02055	COG4862	establishment of competence for transformation
BS21228_RS02060	COG1408	metallophosphoesterase
BS21228_RS02070	COG1388	LysM domain
BS21228_RS02075	COG1266	CAAX protease self-immunity
BS21228_RS02080	COG0514	ATP-dependent DNA helicase (RecQ)
BS21228_RS02085	COG4955	Helix-turn-helix domain
BS21228_RS02090	COG1141	Ferredoxin
BS21228_RS02095	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BS21228_RS02100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BS21228_RS02105	COG0710	3-dehydroquinate dehydratase activity
BS21228_RS02115	COG1595	DNA-templated transcription, initiation
BS21228_RS02120	COG5002	protein histidine kinase activity
BS21228_RS02125	COG0745	RESPONSE REGULATOR receiver
BS21228_RS02130	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BS21228_RS02135	COG1333	cytochrome c biogenesis protein
BS21228_RS02140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS21228_RS02145	COG1187	pseudouridine synthase activity
BS21228_RS02150	COG0700	Nucleoside recognition
BS21228_RS02155	COG2715	membrane protein required for spore maturation
BS21228_RS02160	COG1686	Belongs to the peptidase S11 family
BS21228_RS02170	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BS21228_RS02175	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BS21228_RS02180	COG1547	Domain of unknown function (DUF309)
BS21228_RS02185	COG0456	acetyltransferase
BS21228_RS02190	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BS21228_RS02195	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BS21228_RS02195	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BS21228_RS02200	COG0307	riboflavin synthase, alpha
BS21228_RS02205	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BS21228_RS02205	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BS21228_RS02215	COG0681	Belongs to the peptidase S26 family
BS21228_RS02225	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
BS21228_RS02275	COG3328	transposase activity
BS21228_RS02330	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BS21228_RS02345	COG4086	secreted protein
BS21228_RS02350	COG0019	diaminopimelate decarboxylase activity
BS21228_RS02355	COG0697	spore germination
BS21228_RS02370	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BS21228_RS02390	COG1191	sigma factor activity
BS21228_RS02395	COG2172	sigma factor antagonist activity
BS21228_RS02400	COG1366	Belongs to the anti-sigma-factor antagonist family
BS21228_RS02405	COG1686	Belongs to the peptidase S11 family
BS21228_RS02410	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BS21228_RS02415	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BS21228_RS02420	COG4974	Belongs to the 'phage' integrase family
BS21228_RS02430	COG0735	belongs to the Fur family
BS21228_RS02435	COG1300	Membrane
BS21228_RS02445	COG0281	malic enzyme
BS21228_RS02450	COG1757	Na H antiporter
BS21228_RS02455	COG1027	Aspartate ammonia-lyase
BS21228_RS02460	COG0252	asparaginase activity
BS21228_RS02465	COG1396	sequence-specific DNA binding
BS21228_RS02470	COG1379	DNA repair
BS21228_RS02475	COG0494	nUDIX hydrolase
BS21228_RS02485	COG0667	Aldo Keto reductase
BS21228_RS02495	COG1073	alpha beta
BS21228_RS02505	COG4918	Iron-sulphur cluster biosynthesis
BS21228_RS02510	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BS21228_RS02510	COG0456	acetyltransferase
BS21228_RS02515	COG2329	Antibiotic biosynthesis monooxygenase
BS21228_RS02520	COG0456	acetyltransferase
BS21228_RS02530	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BS21228_RS02540	COG2211	Major facilitator Superfamily
BS21228_RS02550	COG0346	lactoylglutathione lyase activity
BS21228_RS02555	COG1072	(Pantothenic acid kinase))
BS21228_RS02560	COG3048	D-serine ammonia-lyase activity
BS21228_RS02565	COG0300	oxidoreductase activity
BS21228_RS02570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BS21228_RS02575	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BS21228_RS02580	COG4187	Peptidase family M20/M25/M40
BS21228_RS02585	COG1902	pentaerythritol trinitrate reductase activity
BS21228_RS02600	COG0596	Alpha beta hydrolase
BS21228_RS02610	COG1234	tRNA 3'-trailer cleavage
BS21228_RS02615	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BS21228_RS02620	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BS21228_RS02625	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BS21228_RS02635	COG0706	membrane insertase activity
BS21228_RS02640	COG3361	conserved protein (COG2071)
BS21228_RS02645	COG2195	Cleaves the N-terminal amino acid of tripeptides
BS21228_RS02655	COG0346	lactoylglutathione lyase activity
BS21228_RS02660	COG1376	ErfK ybiS ycfS ynhG family protein
BS21228_RS02665	COG4129	membrane
BS21228_RS02670	COG1126	abc transporter atp-binding protein
BS21228_RS02675	COG0765	amino acid transport
BS21228_RS02680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BS21228_RS02690	COG1597	lipid kinase activity
BS21228_RS02700	COG0789	Transcriptional regulator
BS21228_RS02700	COG4978	Transcriptional regulator
BS21228_RS02705	COG0508	dehydrogenase complex catalyzes the overall conversion of
BS21228_RS02710	COG0022	dehydrogenase e1 component
BS21228_RS02715	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BS21228_RS02720	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BS21228_RS02725	COG3426	butyrate kinase activity
BS21228_RS02730	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BS21228_RS02735	COG0280	phosphate acetyltransferase
BS21228_RS02740	COG3290	protein histidine kinase activity
BS21228_RS02740	COG3829	transcription factor binding
BS21228_RS02750	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BS21228_RS02755	COG2079	MmgE PrpD family protein
BS21228_RS02760	COG0372	Belongs to the citrate synthase family
BS21228_RS02765	COG1960	acyl-CoA dehydrogenase activity
BS21228_RS02770	COG1250	3-hydroxyacyl-CoA dehydrogenase
BS21228_RS02775	COG0183	Belongs to the thiolase family
BS21228_RS02780	COG0584	glycerophosphoryl diester phosphodiesterase
BS21228_RS02785	COG0860	N-Acetylmuramoyl-L-alanine amidase
BS21228_RS02795	COG1902	pentaerythritol trinitrate reductase activity
BS21228_RS02800	COG0745	RESPONSE REGULATOR receiver
BS21228_RS02810	COG0750	zinc metalloprotease
BS21228_RS02815	COG0497	DNA recombination
BS21228_RS02820	COG1438	arginine binding
BS21228_RS02825	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BS21228_RS02830	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BS21228_RS02835	COG0142	geranyltranstransferase activity
BS21228_RS02840	COG1722	exodeoxyribonuclease VII activity
BS21228_RS02845	COG1570	exodeoxyribonuclease VII activity
BS21228_RS02850	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BS21228_RS02855	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BS21228_RS02860	COG1302	Protein conserved in bacteria
BS21228_RS02865	COG0439	Biotin carboxylase
BS21228_RS02870	COG0511	ligase activity, forming carbon-carbon bonds
BS21228_RS02915	COG3854	ATPases associated with a variety of cellular activities
BS21228_RS02925	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BS21228_RS02930	COG0006	proline dipeptidase activity
BS21228_RS02935	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BS21228_RS02945	COG3872	metal-dependent enzyme
BS21228_RS02955	COG1752	Esterase of the alpha-beta hydrolase superfamily
BS21228_RS02960	COG1321	iron dependent repressor
BS21228_RS02965	COG0095	Lipoate-protein ligase
BS21228_RS02970	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BS21228_RS02975	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BS21228_RS02980	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BS21228_RS02985	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BS21228_RS02990	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BS21228_RS03005	COG1396	sequence-specific DNA binding
BS21228_RS03015	COG0681	Belongs to the peptidase S26 family
BS21228_RS03040	COG4940	Competence protein ComGF
BS21228_RS03050	COG4970	Tfp pilus assembly protein FimT
BS21228_RS03055	COG4537	Required for transformation and DNA binding
BS21228_RS03060	COG1459	type II secretion system
BS21228_RS03065	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BS21228_RS03070	COG0517	IMP dehydrogenase activity
BS21228_RS03075	COG0598	Magnesium transport protein CorA
BS21228_RS03080	COG1253	flavin adenine dinucleotide binding
BS21228_RS03085	COG1366	Belongs to the anti-sigma-factor antagonist family
BS21228_RS03095	COG1393	Belongs to the ArsC family
BS21228_RS03105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BS21228_RS03115	COG0011	TIGRFAM Protein of
BS21228_RS03125	COG2866	Carboxypeptidase
BS21228_RS03130	COG1368	sulfuric ester hydrolase activity
BS21228_RS03135	COG1940	carbohydrate kinase activity
BS21228_RS03140	COG4483	Protein conserved in bacteria
BS21228_RS03145	COG0705	Rhomboid family
BS21228_RS03145	COG0457	Tetratricopeptide repeat
BS21228_RS03155	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BS21228_RS03165	COG0438	transferase activity, transferring glycosyl groups
BS21228_RS03180	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BS21228_RS03185	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BS21228_RS03190	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BS21228_RS03195	COG0581	inorganic phosphate transmembrane transporter activity
BS21228_RS03200	COG0573	inorganic phosphate transmembrane transporter activity
BS21228_RS03205	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BS21228_RS03210	COG0768	penicillin binding
BS21228_RS03215	COG0477	Major facilitator Superfamily
BS21228_RS03220	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BS21228_RS03225	COG2839	Protein conserved in bacteria
BS21228_RS03230	COG5521	maltodextrose utilization protein MalA
BS21228_RS03235	COG1388	LysM domain
BS21228_RS03240	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BS21228_RS03245	COG4709	membrane
BS21228_RS03250	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BS21228_RS03255	COG0735	belongs to the Fur family
BS21228_RS03260	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BS21228_RS03270	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BS21228_RS03275	COG0513	Belongs to the DEAD box helicase family
BS21228_RS03285	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BS21228_RS03290	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BS21228_RS03295	COG2384	SAM-dependent methyltransferase
BS21228_RS03300	COG2010	Cytochrome c
BS21228_RS03310	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BS21228_RS03315	COG0358	DNA primase activity
BS21228_RS03320	COG1671	Belongs to the UPF0178 family
BS21228_RS03325	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BS21228_RS03330	COG0517	IMP dehydrogenase activity
BS21228_RS03335	COG0751	glycine-tRNA ligase activity
BS21228_RS03340	COG0752	glycyl-tRNA synthetase alpha subunit
BS21228_RS03345	COG1381	Involved in DNA repair and RecF pathway recombination
BS21228_RS03355	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BS21228_RS03360	COG0295	cytidine deaminase activity
BS21228_RS03365	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BS21228_RS03370	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BS21228_RS03375	COG1480	7TM receptor with intracellular HD hydrolase
BS21228_RS03380	COG1702	phosphate starvation-inducible protein PhoH
BS21228_RS03385	COG0561	phosphatase activity
BS21228_RS03400	COG4864	UPF0365 protein
BS21228_RS03405	COG1030	water channel activity
BS21228_RS03410	COG1610	YqeY-like protein
BS21228_RS03425	COG1283	sodium-dependent phosphate transmembrane transporter activity
BS21228_RS03430	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BS21228_RS03435	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BS21228_RS03440	COG2264	protein methyltransferase activity
BS21228_RS03445	COG0484	heat shock protein binding
BS21228_RS03450	COG0443	Heat shock 70 kDa protein
BS21228_RS03455	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BS21228_RS03460	COG1420	regulation of RNA biosynthetic process
BS21228_RS03465	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BS21228_RS03470	COG0481	GTPase activity
BS21228_RS03480	COG0860	N-Acetylmuramoyl-L-alanine amidase
BS21228_RS03485	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BS21228_RS03490	COG0268	Binds directly to 16S ribosomal RNA
BS21228_RS03495	COG1466	dna polymerase III delta subunit
BS21228_RS03505	COG2333	competence protein COMEC
BS21228_RS03505	COG0658	competence protein
BS21228_RS03510	COG2131	deaminase
BS21228_RS03515	COG1596	polysaccharide export
BS21228_RS03515	COG1555	photosystem II stabilization
BS21228_RS03520	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BS21228_RS03525	COG2226	methyltransferase
BS21228_RS03530	COG0799	negative regulation of ribosome biogenesis
BS21228_RS03535	COG1713	HD superfamily hydrolase involved in NAD metabolism
BS21228_RS03540	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BS21228_RS03545	COG1534	Rna-binding protein
BS21228_RS03550	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BS21228_RS03555	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BS21228_RS03560	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BS21228_RS03570	COG2755	lipolytic protein G-D-S-L family
BS21228_RS03575	COG3409	Peptidoglycan-binding domain 1 protein
BS21228_RS03575	COG5632	N-Acetylmuramoyl-L-alanine amidase
BS21228_RS03580	COG0398	Pfam SNARE associated Golgi protein
BS21228_RS03585	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BS21228_RS03595	COG3209	COG3209 Rhs family protein
BS21228_RS03605	COG3328	transposase activity
BS21228_RS03615	COG0114	fumarate hydratase activity
BS21228_RS03620	COG0583	DNA-binding transcription factor activity
BS21228_RS03635	COG0457	Tetratricopeptide repeat
BS21228_RS03760	COG0789	Transcriptional regulator
BS21228_RS03760	COG4978	Transcriptional regulator
BS21228_RS03765	COG2814	Major facilitator Superfamily
BS21228_RS03770	COG0456	acetyltransferase
BS21228_RS03775	COG1253	flavin adenine dinucleotide binding
BS21228_RS03785	COG0697	spore germination
BS21228_RS03790	COG0583	DNA-binding transcription factor activity
BS21228_RS03795	COG2072	flavoprotein involved in K transport
BS21228_RS03800	COG1230	cation diffusion facilitator family transporter
BS21228_RS03810	COG1114	Component of the transport system for branched-chain amino acids
BS21228_RS03815	COG1687	branched-chain amino acid
BS21228_RS03825	COG1522	sequence-specific DNA binding
BS21228_RS03830	COG2732	(Barnase) inhibitor
BS21228_RS03835	COG2124	cytochrome p450
BS21228_RS03845	COG1335	isochorismatase
BS21228_RS03860	COG2318	DinB family
BS21228_RS03870	COG2070	2-Nitropropane dioxygenase
BS21228_RS03885	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BS21228_RS03895	COG3443	Belongs to the bacterial solute-binding protein 9 family
BS21228_RS03900	COG1595	DNA-templated transcription, initiation
BS21228_RS03905	COG0667	Aldo Keto reductase
BS21228_RS03910	COG3409	Peptidoglycan-binding domain 1 protein
BS21228_RS03915	COG5566	PFAM Mor transcription activator
BS21228_RS03925	COG4991	sh3 domain protein
BS21228_RS03930	COG4991	sh3 domain protein
BS21228_RS03935	COG0346	lactoylglutathione lyase activity
BS21228_RS03945	COG5577	PFAM Coat F domain
BS21228_RS03950	COG1063	alcohol dehydrogenase
BS21228_RS03960	COG5577	PFAM Coat F domain
BS21228_RS03965	COG0789	Transcriptional regulator
BS21228_RS03975	COG1064	alcohol dehydrogenase
BS21228_RS03980	COG0693	protein deglycase activity
BS21228_RS03985	COG1621	beta-fructofuranosidase activity
BS21228_RS03990	COG3716	PTS system mannose fructose sorbose family IID component
BS21228_RS03995	COG3715	PTS system
BS21228_RS04000	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS21228_RS04005	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS21228_RS04010	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BS21228_RS04010	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BS21228_RS04015	COG1113	amino acid transport
BS21228_RS04020	COG1280	lysine exporter protein (LysE YggA)
BS21228_RS04025	COG1378	Sugar-specific transcriptional regulator TrmB
BS21228_RS04030	COG1595	DNA-templated transcription, initiation
BS21228_RS04055	COG1309	transcriptional regulator
BS21228_RS04060	COG2226	methyltransferase
BS21228_RS04070	COG2116	formate transmembrane transporter activity
BS21228_RS04075	COG5609	conserved protein (DUF2294)
BS21228_RS04080	COG3383	formate dehydrogenase (NAD+) activity
BS21228_RS04085	COG2427	Protein of unknown function (DUF1641)
BS21228_RS04100	COG0626	cystathionine gamma-synthase activity
BS21228_RS04105	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BS21228_RS04110	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BS21228_RS04115	COG2226	methyltransferase
BS21228_RS04130	COG0768	penicillin binding
BS21228_RS04135	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BS21228_RS04140	COG0572	uridine kinase
BS21228_RS04145	COG0826	peptidase U32
BS21228_RS04150	COG0826	peptidase U32
BS21228_RS04155	COG4122	O-methyltransferase activity
BS21228_RS04160	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BS21228_RS04165	COG3906	Belongs to the UPF0473 family
BS21228_RS04170	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BS21228_RS04175	COG4472	Bacterial protein of unknown function (DUF965)
BS21228_RS04180	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BS21228_RS04185	COG0628	permease
BS21228_RS04190	COG1126	abc transporter atp-binding protein
BS21228_RS04195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BS21228_RS04200	COG0765	amino acid transport
BS21228_RS04205	COG0765	amino acid transport
BS21228_RS04220	COG3881	PFAM PRC-barrel domain
BS21228_RS04225	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BS21228_RS04230	COG0457	Tetratricopeptide repeat
BS21228_RS04235	COG0482	sulfurtransferase activity
BS21228_RS04240	COG1104	cysteine desulfurase activity
BS21228_RS04245	COG1959	2 iron, 2 sulfur cluster binding
BS21228_RS04250	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BS21228_RS04255	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BS21228_RS04265	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BS21228_RS04270	COG0124	histidyl-tRNA synthetase
BS21228_RS04280	COG4991	sh3 domain protein
BS21228_RS04280	COG3103	Sh3 type 3 domain protein
BS21228_RS04280	COG0860	N-Acetylmuramoyl-L-alanine amidase
BS21228_RS04285	COG1490	D-aminoacyl-tRNA deacylase activity
BS21228_RS04290	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BS21228_RS04295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BS21228_RS04300	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BS21228_RS04300	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BS21228_RS04305	COG5416	Lipopolysaccharide assembly protein A domain
BS21228_RS04310	COG0490	domain, Protein
BS21228_RS04315	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BS21228_RS04315	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BS21228_RS04325	COG2244	polysaccharide biosynthetic process
BS21228_RS04330	COG2323	membrane
BS21228_RS04340	COG1862	Preprotein translocase
BS21228_RS04345	COG0343	queuine tRNA-ribosyltransferase activity
BS21228_RS04350	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BS21228_RS04360	COG2255	four-way junction helicase activity
BS21228_RS04365	COG0632	four-way junction helicase activity
BS21228_RS04375	COG2814	Major facilitator Superfamily
BS21228_RS04380	COG0673	inositol 2-dehydrogenase activity
BS21228_RS04385	COG2112	serine threonine protein kinase
BS21228_RS04400	COG1115	amino acid carrier protein
BS21228_RS04405	COG0217	transcriptional regulatory protein
BS21228_RS04415	COG1388	LysM domain
BS21228_RS04420	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BS21228_RS04425	COG0157	Belongs to the NadC ModD family
BS21228_RS04430	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BS21228_RS04435	COG1104	cysteine desulfurase activity
BS21228_RS04440	COG1827	regulation of RNA biosynthetic process
BS21228_RS04445	COG0077	Prephenate dehydratase
BS21228_RS04450	COG4492	Belongs to the UPF0735 family
BS21228_RS04455	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BS21228_RS04460	COG3290	protein histidine kinase activity
BS21228_RS04465	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BS21228_RS04470	COG2868	ribosomal protein
BS21228_RS04475	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BS21228_RS04480	COG1994	Peptidase M50
BS21228_RS04485	COG0739	heme binding
BS21228_RS04490	COG2894	cell division
BS21228_RS04495	COG0850	regulation of cytokinetic process
BS21228_RS04500	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BS21228_RS04510	COG1077	Cell shape determining protein MreB Mrl
BS21228_RS04515	COG2003	Belongs to the UPF0758 family
BS21228_RS04520	COG0424	maF-like protein
BS21228_RS04530	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BS21228_RS04535	COG0285	dihydrofolate synthase activity
BS21228_RS04540	COG0525	valine-tRNA ligase activity
BS21228_RS04550	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BS21228_RS04555	COG1388	LysM domain
BS21228_RS04560	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BS21228_RS04565	COG0113	porphobilinogen synthase activity
BS21228_RS04570	COG1587	Uroporphyrinogen-III synthase
BS21228_RS04575	COG0181	hydroxymethylbilane synthase activity
BS21228_RS04580	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BS21228_RS04585	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BS21228_RS04595	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BS21228_RS04600	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BS21228_RS04605	COG1067	ATP-dependent peptidase activity
BS21228_RS04605	COG0470	DNA polymerase III
BS21228_RS04610	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BS21228_RS04615	COG0544	peptidyl-prolyl cis-trans isomerase activity
BS21228_RS04620	COG1477	protein flavinylation
BS21228_RS04620	COG0457	Tetratricopeptide repeat
BS21228_RS04625	COG0066	3-isopropylmalate dehydratase activity
BS21228_RS04630	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BS21228_RS04635	COG0473	3-isopropylmalate dehydrogenase activity
BS21228_RS04640	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BS21228_RS04645	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BS21228_RS04650	COG0440	acetolactate synthase activity
BS21228_RS04655	COG0028	Belongs to the TPP enzyme family
BS21228_RS04670	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
BS21228_RS04700	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
BS21228_RS04725	COG0622	Phosphoesterase
BS21228_RS04730	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BS21228_RS04735	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BS21228_RS04740	COG5401	PFAM Sporulation and spore germination
BS21228_RS04745	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BS21228_RS04750	COG1846	Transcriptional regulator
BS21228_RS04755	COG2197	response regulator
BS21228_RS04760	COG0824	Thioesterase
BS21228_RS04765	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BS21228_RS04770	COG1053	succinate dehydrogenase
BS21228_RS04775	COG2009	succinate dehydrogenase
BS21228_RS04780	COG1719	4-vinyl reductase, 4VR
BS21228_RS04785	COG0527	aspartate kinase activity
BS21228_RS04795	COG0322	excinuclease ABC activity
BS21228_RS04800	COG3118	belongs to the thioredoxin family
BS21228_RS04805	COG3534	alpha-L-arabinofuranosidase
BS21228_RS04810	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BS21228_RS04815	COG2086	electron transfer activity
BS21228_RS04820	COG1024	Enoyl-CoA hydratase
BS21228_RS04825	COG1309	transcriptional regulator
BS21228_RS04830	COG0318	PFAM AMP-dependent synthetase and ligase
BS21228_RS04835	COG3766	membrane
BS21228_RS04840	COG1193	negative regulation of DNA recombination
BS21228_RS04845	COG1796	DNA polymerase
BS21228_RS04845	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BS21228_RS04850	COG1286	toxin biosynthetic process
BS21228_RS04855	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BS21228_RS04860	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BS21228_RS04865	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BS21228_RS04865	COG0072	phenylalanine-tRNA ligase activity
BS21228_RS04870	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BS21228_RS04880	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BS21228_RS04890	COG3835	regulator
BS21228_RS04895	COG0277	FAD linked oxidase domain protein
BS21228_RS04900	COG0247	lactate metabolic process
BS21228_RS04905	COG0346	lactoylglutathione lyase activity
BS21228_RS04910	COG1966	Carbon starvation protein
BS21228_RS04915	COG3534	alpha-L-arabinofuranosidase
BS21228_RS04920	COG0395	ABC-type sugar transport system, permease component
BS21228_RS04925	COG1175	transmembrane transport
BS21228_RS04930	COG1653	transport
BS21228_RS04935	COG0371	Dehydrogenase
BS21228_RS04940	COG0647	UMP catabolic process
BS21228_RS04945	COG0235	Class ii aldolase
BS21228_RS04950	COG1069	ribulokinase activity
BS21228_RS04955	COG2160	L-arabinose isomerase activity
BS21228_RS04965	COG1363	Peptidase, m42
BS21228_RS04975	COG3326	Membrane
BS21228_RS04980	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BS21228_RS04985	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BS21228_RS04990	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BS21228_RS05000	COG1346	cytolysis
BS21228_RS05005	COG1380	Effector of murein hydrolase LrgA
BS21228_RS05010	COG3279	Response regulator of the LytR AlgR family
BS21228_RS05015	COG3275	phosphorelay sensor kinase activity
BS21228_RS05020	COG1011	Hydrolase
BS21228_RS05025	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BS21228_RS05035	COG0398	Pfam SNARE associated Golgi protein
BS21228_RS05040	COG1484	DNA-dependent DNA replication
BS21228_RS05045	COG3611	Membrane attachment protein
BS21228_RS05050	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BS21228_RS05055	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BS21228_RS05060	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BS21228_RS05065	COG1733	regulation of RNA biosynthetic process
BS21228_RS05070	COG2814	Major facilitator Superfamily
BS21228_RS05075	COG0656	L-ascorbic acid biosynthetic process
BS21228_RS05080	COG0237	dephospho-CoA kinase activity
BS21228_RS05085	COG1971	Probably functions as a manganese efflux pump
BS21228_RS05090	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BS21228_RS05095	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BS21228_RS05095	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BS21228_RS05100	COG5002	protein histidine kinase activity
BS21228_RS05105	COG0745	RESPONSE REGULATOR receiver
BS21228_RS05110	COG0039	L-malate dehydrogenase activity
BS21228_RS05115	COG0538	isocitrate dehydrogenase activity
BS21228_RS05120	COG0372	Belongs to the citrate synthase family
BS21228_RS05125	COG2707	UPF0756 membrane protein
BS21228_RS05130	COG0628	permease
BS21228_RS05135	COG3030	protein affecting phage T7 exclusion by the F plasmid
BS21228_RS05140	COG0469	pyruvate kinase activity
BS21228_RS05145	COG0205	6-phosphofructokinase activity
BS21228_RS05150	COG0825	malonyl-CoA metabolic process
BS21228_RS05155	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BS21228_RS05160	COG0281	malic enzyme
BS21228_RS05165	COG0587	DNA-directed DNA polymerase activity
BS21228_RS05185	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BS21228_RS05195	COG4109	DRTGG domain
BS21228_RS05205	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BS21228_RS05210	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_RS05220	COG0165	Argininosuccinate lyase
BS21228_RS05225	COG0137	argininosuccinate synthase activity
BS21228_RS05230	COG0521	Mo-molybdopterin cofactor biosynthetic process
BS21228_RS05235	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BS21228_RS05245	COG0827	DNA restriction-modification system
BS21228_RS05250	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BS21228_RS05255	COG3874	Sporulation protein YtfJ
BS21228_RS05265	COG1714	RDD family
BS21228_RS05270	COG0616	signal peptide processing
BS21228_RS05275	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BS21228_RS05280	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BS21228_RS05285	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BS21228_RS05295	COG0301	tRNA thio-modification
BS21228_RS05300	COG1104	cysteine desulfurase activity
BS21228_RS05305	COG1114	Component of the transport system for branched-chain amino acids
BS21228_RS05310	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BS21228_RS05315	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BS21228_RS05320	COG1309	transcriptional regulator
BS21228_RS05325	COG1956	GAF domain-containing protein
BS21228_RS05330	COG2199	diguanylate cyclase activity
BS21228_RS05330	COG2203	Gaf domain
BS21228_RS05340	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BS21228_RS05345	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BS21228_RS05355	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BS21228_RS05360	COG0454	-acetyltransferase
BS21228_RS05365	COG0517	IMP dehydrogenase activity
BS21228_RS05370	COG0123	including yeast histone deacetylase and acetoin utilization protein
BS21228_RS05375	COG1360	Flagellar Motor Protein
BS21228_RS05380	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BS21228_RS05385	COG1609	Transcriptional regulator
BS21228_RS05390	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BS21228_RS05390	COG1605	Chorismate mutase
BS21228_RS05395	COG3118	belongs to the thioredoxin family
BS21228_RS05400	COG4980	gas vesicle protein
BS21228_RS05405	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BS21228_RS05410	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BS21228_RS05415	COG1674	ftsk spoiiie
BS21228_RS05420	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BS21228_RS05425	COG4848	Belongs to the UPF0354 family
BS21228_RS05430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS21228_RS05440	COG1363	Peptidase, m42
BS21228_RS05445	COG5584	Small secreted protein
BS21228_RS05450	COG0281	malic enzyme
BS21228_RS05455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BS21228_RS05460	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BS21228_RS05470	COG0510	thiamine kinase activity
BS21228_RS05475	COG1523	belongs to the glycosyl hydrolase 13 family
BS21228_RS05480	COG1597	lipid kinase activity
BS21228_RS05490	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BS21228_RS05495	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BS21228_RS05500	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BS21228_RS05505	COG2252	PERMEase
BS21228_RS05510	COG4473	ABC transporter
BS21228_RS05515	COG1131	(ABC) transporter
BS21228_RS05520	COG1349	DNA-binding transcription factor activity
BS21228_RS05525	COG1187	pseudouridine synthase activity
BS21228_RS05530	COG2244	polysaccharide biosynthetic process
BS21228_RS05535	COG2081	HI0933 family
BS21228_RS05540	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BS21228_RS05560	COG1653	transport
BS21228_RS05565	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BS21228_RS05570	COG4209	transmembrane transport
BS21228_RS05580	COG1653	transport
BS21228_RS05585	COG0395	ABC-type sugar transport system, permease component
BS21228_RS05590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BS21228_RS05595	COG2124	cytochrome p450
BS21228_RS05615	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BS21228_RS05625	COG1073	alpha beta
BS21228_RS05630	COG1609	Transcriptional regulator
BS21228_RS05635	COG1653	transport
BS21228_RS05640	COG1175	transmembrane transport
BS21228_RS05645	COG0395	ABC-type sugar transport system, permease component
BS21228_RS05650	COG1486	melibiose metabolic process
BS21228_RS05655	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BS21228_RS05660	COG0495	leucyl-tRNA aminoacylation
BS21228_RS05670	COG2202	Pas domain
BS21228_RS05670	COG1366	Belongs to the anti-sigma-factor antagonist family
BS21228_RS05675	COG2814	Major facilitator Superfamily
BS21228_RS05680	COG2433	Pfam Transposase IS66
BS21228_RS05685	COG0577	efflux transmembrane transporter activity
BS21228_RS05690	COG1136	(ABC) transporter
BS21228_RS05695	COG2205	protein histidine kinase activity
BS21228_RS05700	COG0745	RESPONSE REGULATOR receiver
BS21228_RS05705	COG0577	efflux transmembrane transporter activity
BS21228_RS05710	COG1136	(ABC) transporter
BS21228_RS05725	COG1131	(ABC) transporter
BS21228_RS05730	COG1725	Transcriptional regulator
BS21228_RS05740	COG1242	4 iron, 4 sulfur cluster binding
BS21228_RS05745	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BS21228_RS05755	COG2267	carboxylic ester hydrolase activity
BS21228_RS05760	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BS21228_RS05765	COG1113	amino acid transport
BS21228_RS05770	COG0367	asparagine synthase
BS21228_RS05775	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BS21228_RS05780	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BS21228_RS05790	COG1506	peptidase
BS21228_RS05795	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BS21228_RS05800	COG1116	anion transmembrane transporter activity
BS21228_RS05805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BS21228_RS05810	COG0494	nUDIX hydrolase
BS21228_RS05815	COG4824	toxin secretion phage lysis holin
BS21228_RS05820	COG0783	Belongs to the Dps family
BS21228_RS05835	COG1854	S-ribosylhomocysteine lyase activity
BS21228_RS05840	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BS21228_RS05845	COG0288	reversible hydration of carbon dioxide
BS21228_RS05850	COG0254	rRNA binding
BS21228_RS05855	COG1271	oxidase subunit
BS21228_RS05860	COG1294	oxidase, subunit
BS21228_RS05870	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BS21228_RS05875	COG1321	iron dependent repressor
BS21228_RS05875	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BS21228_RS05880	COG1121	(ABC) transporter
BS21228_RS05885	COG0803	Belongs to the bacterial solute-binding protein 9 family
BS21228_RS05890	COG4948	Mandelate Racemase Muconate Lactonizing
BS21228_RS05895	COG0318	PFAM AMP-dependent synthetase and ligase
BS21228_RS05900	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BS21228_RS05905	COG0596	Alpha beta hydrolase
BS21228_RS05910	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BS21228_RS05915	COG1169	isochorismate synthase
BS21228_RS05920	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BS21228_RS05925	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BS21228_RS05930	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BS21228_RS05935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BS21228_RS05940	COG0438	transferase activity, transferring glycosyl groups
BS21228_RS05950	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BS21228_RS05955	COG0438	transferase activity, transferring glycosyl groups
BS21228_RS05960	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BS21228_RS05965	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
BS21228_RS05970	COG0058	SHG alpha-glucan phosphorylase activity
BS21228_RS05975	COG0297	glycogen (starch) synthase activity
BS21228_RS05980	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BS21228_RS05985	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BS21228_RS05990	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BS21228_RS06115	COG3859	Proton-coupled thiamine transporter YuaJ
BS21228_RS06120	COG1247	-acetyltransferase
BS21228_RS06125	COG2268	Band 7 protein
BS21228_RS06130	COG1585	Membrane protein implicated in regulation of membrane protease activity
BS21228_RS06135	COG2318	DinB family
BS21228_RS06145	COG1454	alcohol dehydrogenase
BS21228_RS06150	COG1012	belongs to the aldehyde dehydrogenase family
BS21228_RS06155	COG1510	regulation of RNA biosynthetic process
BS21228_RS06165	COG0569	domain protein
BS21228_RS06170	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BS21228_RS06175	COG4682	membrane
BS21228_RS06180	COG1705	Flagellar rod assembly protein muramidase FlgJ
BS21228_RS06185	COG0477	Major facilitator Superfamily
BS21228_RS06190	COG5553	Cysteine dioxygenase type I
BS21228_RS06200	COG1968	undecaprenyl-diphosphatase activity
BS21228_RS06205	COG0628	permease
BS21228_RS06210	COG0673	inositol 2-dehydrogenase activity
BS21228_RS06215	COG4806	L-rhamnose isomerase
BS21228_RS06220	COG3254	rhamnose metabolic process
BS21228_RS06225	COG1070	Carbohydrate kinase
BS21228_RS06230	COG1349	DNA-binding transcription factor activity
BS21228_RS06235	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_RS06235	COG3347	Dehydrogenase
BS21228_RS06250	COG0840	transmembrane signaling receptor activity
BS21228_RS06260	COG0840	transmembrane signaling receptor activity
BS21228_RS06275	COG0432	Pfam Uncharacterised protein family UPF0047
BS21228_RS06280	COG0366	Alpha amylase catalytic
BS21228_RS06285	COG1253	flavin adenine dinucleotide binding
BS21228_RS06290	COG2738	Putative neutral zinc metallopeptidase
BS21228_RS06305	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BS21228_RS06320	COG0166	Belongs to the GPI family
BS21228_RS06325	COG1979	alcohol dehydrogenase
BS21228_RS06330	COG1979	alcohol dehydrogenase
BS21228_RS06335	COG2155	Conserved Protein
BS21228_RS06340	COG1098	S1 RNA binding domain
BS21228_RS06345	COG0436	Aminotransferase
BS21228_RS06350	COG1522	sequence-specific DNA binding
BS21228_RS06355	COG2267	carboxylic ester hydrolase activity
BS21228_RS06365	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BS21228_RS06370	COG2205	protein histidine kinase activity
BS21228_RS06380	COG5018	Exonuclease
BS21228_RS06390	COG2814	Major facilitator Superfamily
BS21228_RS06395	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BS21228_RS06400	COG3011	Protein conserved in bacteria
BS21228_RS06410	COG3290	protein histidine kinase activity
BS21228_RS06415	COG4565	transcriptional regulatory protein
BS21228_RS06420	COG1744	ABC transporter substrate-binding protein PnrA-like
BS21228_RS06425	COG3845	ABC transporter
BS21228_RS06430	COG4603	Belongs to the binding-protein-dependent transport system permease family
BS21228_RS06435	COG1079	Belongs to the binding-protein-dependent transport system permease family
BS21228_RS06440	COG3493	citrate carrier protein
BS21228_RS06450	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BS21228_RS06450	COG2111	Na H antiporter
BS21228_RS06455	COG2111	Na H antiporter
BS21228_RS06460	COG1006	Multisubunit Na H antiporter MnhC subunit
BS21228_RS06465	COG0651	ATP synthesis coupled electron transport
BS21228_RS06470	COG1863	multisubunit Na H antiporter MnhE subunit
BS21228_RS06475	COG2212	antiporter activity
BS21228_RS06480	COG1320	monovalent cation:proton antiporter activity
BS21228_RS06485	COG2050	protein possibly involved in aromatic compounds catabolism
BS21228_RS06490	COG2197	response regulator
BS21228_RS06495	COG4585	Histidine kinase
BS21228_RS06505	COG0142	geranyltranstransferase activity
BS21228_RS06520	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BS21228_RS06525	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BS21228_RS06530	COG1335	isochorismatase
BS21228_RS06535	COG5506	Protein of unknown function (DUF1694)
BS21228_RS06550	COG0628	permease
BS21228_RS06565	COG1418	mRNA catabolic process
BS21228_RS06570	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_RS06580	COG1511	domain protein
BS21228_RS06585	COG1674	ftsk spoiiie
BS21228_RS06585	COG0433	COG0433 Predicted ATPase
BS21228_RS06590	COG4499	WXG100 protein secretion system (Wss), protein YukC
BS21228_RS06595	COG5417	Belongs to the EsaB family
BS21228_RS06600	COG4842	Belongs to the WXG100 family
BS21228_RS06610	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BS21228_RS06610	COG2508	Transcriptional regulator
BS21228_RS06615	COG0686	Belongs to the AlaDH PNT family
BS21228_RS06620	COG5634	Uncharacterized conserved protein (DUF2278)
BS21228_RS06625	COG3251	PFAM MbtH domain protein
BS21228_RS06630	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BS21228_RS06635	COG1535	isochorismatase
BS21228_RS06635	COG3433	isochorismatase activity
BS21228_RS06640	COG1021	2,3-dihydroxybenzoate-AMP ligase
BS21228_RS06645	COG1169	isochorismate synthase
BS21228_RS06650	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_RS06655	COG2819	hydrolase of the alpha beta superfamily
BS21228_RS06660	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BS21228_RS06665	COG1268	BioY protein
BS21228_RS06670	COG2056	Na+-H+ antiporter family
BS21228_RS06675	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BS21228_RS06680	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BS21228_RS06685	COG3584	3D domain protein
BS21228_RS06700	COG1252	NADH dehydrogenase
BS21228_RS06705	COG0492	ferredoxin-NADP+ reductase activity
BS21228_RS06715	COG0516	GMP reductase activity
BS21228_RS06720	COG2808	Putative FMN-binding domain
BS21228_RS06725	COG0456	acetyltransferase
BS21228_RS06825	COG0582	viral genome integration into host DNA
BS21228_RS06835	COG4974	Belongs to the 'phage' integrase family
BS21228_RS06840	COG0316	Belongs to the HesB IscA family
BS21228_RS06845	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BS21228_RS06850	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BS21228_RS06855	COG4844	belongs to the
BS21228_RS06860	COG1252	NADH dehydrogenase
BS21228_RS06865	COG4837	Protein of unknown function (DUF1462)
BS21228_RS06870	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BS21228_RS06875	COG0823	Involved in the tonB-independent uptake of proteins
BS21228_RS06875	COG1506	peptidase
BS21228_RS06875	COG4946	Tricorn protease homolog
BS21228_RS06880	COG0083	homoserine kinase activity
BS21228_RS06885	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BS21228_RS06890	COG0460	homoserine dehydrogenase
BS21228_RS06895	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BS21228_RS06900	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BS21228_RS06905	COG0647	UMP catabolic process
BS21228_RS06910	COG2445	Protein of unknown function DUF86
BS21228_RS06915	COG4470	Protein conserved in bacteria
BS21228_RS06925	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BS21228_RS06930	COG0739	heme binding
BS21228_RS06940	COG3377	Domain of unknown function (DUF1805)
BS21228_RS06945	COG0737	Belongs to the 5'-nucleotidase family
BS21228_RS06950	COG0730	response to heat
BS21228_RS06955	COG1801	Protein of unknown function DUF72
BS21228_RS06965	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BS21228_RS06970	COG2508	Transcriptional regulator
BS21228_RS06975	COG2233	PERMEase
BS21228_RS06980	COG2233	PERMEase
BS21228_RS06985	COG3195	allantoin biosynthetic process
BS21228_RS06985	COG3648	Uricase
BS21228_RS06990	COG2351	hydroxyisourate hydrolase activity
BS21228_RS07000	COG2080	2 iron, 2 sulfur cluster binding
BS21228_RS07005	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BS21228_RS07010	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BS21228_RS07015	COG2068	MobA-Related Protein
BS21228_RS07020	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BS21228_RS07025	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BS21228_RS07030	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BS21228_RS07035	COG2356	endonuclease I
BS21228_RS07040	COG3842	ATPase activity
BS21228_RS07045	COG2188	Transcriptional regulator
BS21228_RS07050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BS21228_RS07060	COG1175	transmembrane transport
BS21228_RS07065	COG1653	transport
BS21228_RS07070	COG2222	sugar isomerase
BS21228_RS07075	COG0322	excinuclease ABC activity
BS21228_RS07080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BS21228_RS07095	COG0346	lactoylglutathione lyase activity
BS21228_RS07100	COG0640	Transcriptional regulator
BS21228_RS07105	COG0719	Fe-S assembly protein
BS21228_RS07110	COG0822	iron-sulfur transferase activity
BS21228_RS07115	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BS21228_RS07120	COG0719	Fe-S assembly protein
BS21228_RS07125	COG0396	ATPase activity
BS21228_RS07145	COG1464	Belongs to the NlpA lipoprotein family
BS21228_RS07150	COG2011	ABC-type metal ion transport system permease component
BS21228_RS07155	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BS21228_RS07165	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS21228_RS07170	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BS21228_RS07180	COG0509	glycine decarboxylation via glycine cleavage system
BS21228_RS07185	COG1393	Belongs to the ArsC family
BS21228_RS07190	COG1960	acyl-CoA dehydrogenase activity
BS21228_RS07195	COG0183	Belongs to the thiolase family
BS21228_RS07200	COG1250	3-hydroxyacyl-CoA dehydrogenase
BS21228_RS07200	COG1024	Enoyl-CoA hydratase
BS21228_RS07220	COG5577	PFAM Coat F domain
BS21228_RS07225	COG1846	Transcriptional regulator
BS21228_RS07230	COG0477	Major facilitator Superfamily
BS21228_RS07235	COG1942	4-Oxalocrotonate Tautomerase
BS21228_RS07240	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_RS07245	COG0583	DNA-binding transcription factor activity
BS21228_RS07255	COG1120	ATPase activity
BS21228_RS07275	COG1131	(ABC) transporter
BS21228_RS07325	COG0783	Belongs to the Dps family
BS21228_RS07330	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BS21228_RS07335	COG0745	RESPONSE REGULATOR receiver
BS21228_RS07340	COG2205	protein histidine kinase activity
BS21228_RS07340	COG2770	Histidine kinase
BS21228_RS07350	COG1309	transcriptional regulator
BS21228_RS07355	COG0114	fumarate hydratase activity
BS21228_RS07365	COG0697	spore germination
BS21228_RS07370	COG0814	amino acid
BS21228_RS07380	COG2197	response regulator
BS21228_RS07385	COG4585	Histidine kinase
BS21228_RS07390	COG4758	membrane
BS21228_RS07395	COG3595	metallopeptidase activity
BS21228_RS07400	COG1842	Phage shock protein A
BS21228_RS07405	COG4758	membrane
BS21228_RS07410	COG2814	Major facilitator Superfamily
BS21228_RS07415	COG2096	Adenosyltransferase
BS21228_RS07420	COG1120	ATPase activity
BS21228_RS07425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS21228_RS07430	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS21228_RS07435	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_RS07440	COG3386	PFAM SMP-30 Gluconolaconase
BS21228_RS07445	COG2205	protein histidine kinase activity
BS21228_RS07450	COG0745	RESPONSE REGULATOR receiver
BS21228_RS07470	COG2140	Oxalate decarboxylase
BS21228_RS07480	COG0577	efflux transmembrane transporter activity
BS21228_RS07485	COG1136	(ABC) transporter
BS21228_RS07490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BS21228_RS07495	COG1120	ATPase activity
BS21228_RS07500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS21228_RS07505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS21228_RS07510	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS21228_RS07520	COG0531	amino acid
BS21228_RS07535	COG1988	membrane-bound metal-dependent
BS21228_RS07540	COG1368	sulfuric ester hydrolase activity
BS21228_RS07545	COG1910	domain protein
BS21228_RS07550	COG0725	ABC transporter, periplasmic molybdate-binding protein
BS21228_RS07555	COG4149	molybdate abc transporter
BS21228_RS07560	COG0656	L-ascorbic acid biosynthetic process
BS21228_RS07570	COG0025	NhaP-type Na H and K H
BS21228_RS07575	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BS21228_RS07580	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BS21228_RS07585	COG3973	AAA domain
BS21228_RS07595	COG2860	membrane
BS21228_RS07600	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BS21228_RS07605	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BS21228_RS07610	COG2217	Heavy metal translocating P-type atpase
BS21228_RS07615	COG2217	Heavy metal translocating P-type atpase
BS21228_RS07620	COG2608	mercury ion transmembrane transporter activity
BS21228_RS07625	COG1937	Protein conserved in bacteria
BS21228_RS07630	COG0673	inositol 2-dehydrogenase activity
BS21228_RS07640	COG1289	transmembrane transporter activity
BS21228_RS07650	COG2076	Multidrug Resistance protein
BS21228_RS07655	COG1309	transcriptional regulator
BS21228_RS07660	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_RS07670	COG5444	nuclease activity
BS21228_RS07685	COG3409	Peptidoglycan-binding domain 1 protein
BS21228_RS07685	COG5632	N-Acetylmuramoyl-L-alanine amidase
BS21228_RS07690	COG4824	toxin secretion phage lysis holin
BS21228_RS07715	COG3942	CHAP domain
BS21228_RS07715	COG1705	Flagellar rod assembly protein muramidase FlgJ
BS21228_RS07935	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BS21228_RS07940	COG0557	exoribonuclease II activity
BS21228_RS07945	COG1647	Serine aminopeptidase, S33
BS21228_RS07950	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BS21228_RS07955	COG0596	Alpha beta hydrolase
BS21228_RS07960	COG1476	TRANSCRIPTIONal
BS21228_RS07965	COG1396	sequence-specific DNA binding
BS21228_RS07970	COG1396	sequence-specific DNA binding
BS21228_RS07975	COG1733	regulation of RNA biosynthetic process
BS21228_RS07980	COG0840	transmembrane signaling receptor activity
BS21228_RS07985	COG1174	glycine betaine transport
BS21228_RS07990	COG1732	Glycine betaine
BS21228_RS07995	COG1174	glycine betaine transport
BS21228_RS08000	COG0517	IMP dehydrogenase activity
BS21228_RS08000	COG1125	glycine betaine transport
BS21228_RS08005	COG1510	regulation of RNA biosynthetic process
BS21228_RS08010	COG1174	glycine betaine transport
BS21228_RS08015	COG1732	Glycine betaine
BS21228_RS08020	COG1174	glycine betaine transport
BS21228_RS08025	COG0517	IMP dehydrogenase activity
BS21228_RS08025	COG1125	glycine betaine transport
BS21228_RS08030	COG1510	regulation of RNA biosynthetic process
BS21228_RS08035	COG2095	MarC family integral membrane protein
BS21228_RS08045	COG3064	Membrane
BS21228_RS08050	COG4640	response to antibiotic
BS21228_RS08055	COG0456	acetyltransferase
BS21228_RS08060	COG0148	phosphopyruvate hydratase activity
BS21228_RS08065	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BS21228_RS08070	COG0149	triose-phosphate isomerase activity
BS21228_RS08075	COG0126	phosphoglycerate kinase activity
BS21228_RS08080	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BS21228_RS08085	COG2390	Transcriptional regulator
BS21228_RS08090	COG2814	Major facilitator Superfamily
BS21228_RS08095	COG1609	Transcriptional regulator
BS21228_RS08100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BS21228_RS08110	COG0583	DNA-binding transcription factor activity
BS21228_RS08115	COG0697	spore germination
BS21228_RS08120	COG1113	amino acid transport
BS21228_RS08130	COG1556	Lactate utilization protein
BS21228_RS08135	COG1139	Iron-sulfur cluster binding protein
BS21228_RS08140	COG0247	lactate metabolic process
BS21228_RS08145	COG2197	response regulator
BS21228_RS08150	COG4585	Histidine kinase
BS21228_RS08155	COG0842	Transport permease protein
BS21228_RS08160	COG1131	(ABC) transporter
BS21228_RS08180	COG0596	Alpha beta hydrolase
BS21228_RS08185	COG2208	phosphoserine phosphatase activity
BS21228_RS08190	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BS21228_RS08195	COG1874	Beta-galactosidase
BS21228_RS08200	COG3833	ABC-type maltose transport systems, permease component
BS21228_RS08205	COG1175	transmembrane transport
BS21228_RS08210	COG2182	Extracellular solute-binding protein
BS21228_RS08215	COG1609	Transcriptional regulator
BS21228_RS08220	COG2186	Transcriptional regulator
BS21228_RS08225	COG1620	l-lactate permease
BS21228_RS08230	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BS21228_RS08240	COG5039	Polysaccharide pyruvyl transferase
BS21228_RS08245	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BS21228_RS08250	COG0110	maltose O-acetyltransferase activity
BS21228_RS08255	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BS21228_RS08260	COG2244	polysaccharide biosynthetic process
BS21228_RS08265	COG1216	Glycosyl transferase, family 2
BS21228_RS08270	COG5039	Polysaccharide pyruvyl transferase
BS21228_RS08275	COG1216	Glycosyl transferase, family 2
BS21228_RS08285	COG0438	transferase activity, transferring glycosyl groups
BS21228_RS08290	COG1215	transferase activity, transferring glycosyl groups
BS21228_RS08300	COG1086	Polysaccharide biosynthesis protein
BS21228_RS08305	COG0489	protein tyrosine kinase activity
BS21228_RS08310	COG3944	biosynthesis protein
BS21228_RS08315	COG1396	sequence-specific DNA binding
BS21228_RS08320	COG2272	Belongs to the type-B carboxylesterase lipase family
BS21228_RS08330	COG3479	Phenolic acid decarboxylase
BS21228_RS08345	COG1794	racemase activity, acting on amino acids and derivatives
BS21228_RS08355	COG1621	beta-fructofuranosidase activity
BS21228_RS08360	COG1621	beta-fructofuranosidase activity
BS21228_RS08365	COG0531	amino acid
BS21228_RS08370	COG1309	transcriptional regulator
BS21228_RS08375	COG2076	Multidrug Resistance protein
BS21228_RS08380	COG2076	Multidrug Resistance protein
BS21228_RS08400	COG1674	ftsk spoiiie
BS21228_RS08420	COG1388	LysM domain
BS21228_RS08420	COG5632	N-Acetylmuramoyl-L-alanine amidase
BS21228_RS08420	COG3409	Peptidoglycan-binding domain 1 protein
BS21228_RS08455	COG1705	Flagellar rod assembly protein muramidase FlgJ
BS21228_RS08535	COG0582	viral genome integration into host DNA
BS21228_RS08635	COG4974	Belongs to the 'phage' integrase family
BS21228_RS08645	COG0740	serine-type endopeptidase activity
BS21228_RS08650	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BS21228_RS08655	COG0366	Alpha amylase catalytic
BS21228_RS08660	COG1554	hydrolase, family 65, central catalytic
BS21228_RS08665	COG5521	maltodextrose utilization protein MalA
BS21228_RS08670	COG3833	ABC-type maltose transport systems, permease component
BS21228_RS08675	COG1175	transmembrane transport
BS21228_RS08680	COG2182	Extracellular solute-binding protein
BS21228_RS08690	COG1609	Transcriptional regulator
BS21228_RS08695	COG1611	Belongs to the LOG family
BS21228_RS08705	COG0659	secondary active sulfate transmembrane transporter activity
BS21228_RS08710	COG0288	reversible hydration of carbon dioxide
BS21228_RS08715	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BS21228_RS08720	COG0577	efflux transmembrane transporter activity
BS21228_RS08725	COG1136	(ABC) transporter
BS21228_RS08730	COG5002	protein histidine kinase activity
BS21228_RS08735	COG0745	RESPONSE REGULATOR receiver
BS21228_RS08745	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BS21228_RS08750	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS21228_RS08755	COG1481	regulation of sporulation
BS21228_RS08760	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BS21228_RS08765	COG1660	Displays ATPase and GTPase activities
BS21228_RS08770	COG1051	belongs to the nudix hydrolase family
BS21228_RS08775	COG0492	ferredoxin-NADP+ reductase activity
BS21228_RS08785	COG0457	Tetratricopeptide repeat
BS21228_RS08790	COG1132	(ABC) transporter
BS21228_RS08810	COG0140	phosphoribosyl-ATP diphosphatase activity
BS21228_RS08810	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BS21228_RS08815	COG0107	imidazoleglycerol-phosphate synthase activity
BS21228_RS08820	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BS21228_RS08825	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BS21228_RS08830	COG0131	Imidazoleglycerol-phosphate dehydratase
BS21228_RS08835	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BS21228_RS08840	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BS21228_RS08845	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BS21228_RS08850	COG4990	cell redox homeostasis
BS21228_RS08855	COG5297	Belongs to the glycosyl hydrolase family 6
BS21228_RS08870	COG0546	phosphoglycolate phosphatase activity
BS21228_RS08875	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BS21228_RS08880	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BS21228_RS08885	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BS21228_RS08890	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BS21228_RS08895	COG0363	glucosamine-6-phosphate deaminase activity
BS21228_RS08900	COG2188	Transcriptional regulator
BS21228_RS08905	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BS21228_RS08920	COG1950	PFAM Membrane protein of
BS21228_RS08925	COG1983	PspC domain protein
BS21228_RS08930	COG3595	metallopeptidase activity
BS21228_RS08945	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BS21228_RS08950	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BS21228_RS08955	COG0556	nucleotide-excision repair
BS21228_RS08960	COG4897	Protein conserved in bacteria
BS21228_RS08965	COG0574	Belongs to the PEP-utilizing enzyme family
BS21228_RS08965	COG3848	Pyruvate phosphate dikinase
BS21228_RS08970	COG1309	transcriptional regulator
BS21228_RS08975	COG2814	Major facilitator Superfamily
BS21228_RS08980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BS21228_RS08990	COG3409	Peptidoglycan-binding domain 1 protein
BS21228_RS08990	COG0793	Belongs to the peptidase S41A family
BS21228_RS08995	COG2177	Part of the ABC transporter FtsEX involved in
BS21228_RS09000	COG2884	Cell division ATP-binding protein ftsE
BS21228_RS09005	COG2010	Cytochrome c
BS21228_RS09010	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BS21228_RS09020	COG0653	protein targeting
BS21228_RS09025	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BS21228_RS09040	COG1516	flagellar protein fliS
BS21228_RS09045	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BS21228_RS09050	COG1334	flagellar protein FlaG
BS21228_RS09055	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BS21228_RS09060	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BS21228_RS09065	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BS21228_RS09075	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BS21228_RS09080	COG4786	Flagellar basal body rod
BS21228_RS09080	COG1256	bacterial-type flagellum assembly
BS21228_RS09085	COG3418	PFAM FlgN family protein
BS21228_RS09090	COG2747	anti-sigma28 factor FlgM
BS21228_RS09100	COG1040	competence protein
BS21228_RS09110	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BS21228_RS09115	COG1307	EDD domain protein, DegV family
BS21228_RS09120	COG2197	response regulator
BS21228_RS09125	COG4585	Histidine kinase
BS21228_RS09130	COG1739	Uncharacterized protein family UPF0029
BS21228_RS09135	COG1316	TRANSCRIPTIONal
BS21228_RS09170	COG1131	(ABC) transporter
BS21228_RS09180	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BS21228_RS09185	COG0438	transferase activity, transferring glycosyl groups
BS21228_RS09190	COG1215	transferase activity, transferring glycosyl groups
BS21228_RS09195	COG3206	protein involved in exopolysaccharide biosynthesis
BS21228_RS09200	COG3307	-O-antigen
BS21228_RS09210	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BS21228_RS09215	COG0438	transferase activity, transferring glycosyl groups
BS21228_RS09215	COG0297	glycogen (starch) synthase activity
BS21228_RS09220	COG2244	polysaccharide biosynthetic process
BS21228_RS09235	COG2247	cell wall binding repeat
BS21228_RS09235	COG0860	N-Acetylmuramoyl-L-alanine amidase
BS21228_RS09240	COG2247	cell wall binding repeat
BS21228_RS09240	COG2385	sporulation resulting in formation of a cellular spore
BS21228_RS09270	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BS21228_RS09275	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BS21228_RS09285	COG1134	teichoic acid transport
BS21228_RS09290	COG1682	transport, permease protein
BS21228_RS09305	COG0463	Glycosyl transferase, family 2
BS21228_RS09305	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BS21228_RS09310	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BS21228_RS09315	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BS21228_RS09320	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BS21228_RS09325	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BS21228_RS09330	COG4193	domain, Protein
BS21228_RS09335	COG1482	cell wall glycoprotein biosynthetic process
BS21228_RS09340	COG0697	spore germination
BS21228_RS09345	COG0814	amino acid
BS21228_RS09360	COG1316	TRANSCRIPTIONal
BS21228_RS09365	COG0561	phosphatase activity
BS21228_RS09370	COG0791	NLP P60 protein
BS21228_RS09380	COG2843	Capsule synthesis protein
BS21228_RS09390	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BS21228_RS09400	COG1609	Transcriptional regulator
BS21228_RS09405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BS21228_RS09410	COG1869	D-ribose catabolic process
BS21228_RS09415	COG1129	ABC transporter
BS21228_RS09420	COG1172	Belongs to the binding-protein-dependent transport system permease family
BS21228_RS09425	COG1879	ABC-type sugar transport system periplasmic component
BS21228_RS09430	COG3103	Sh3 type 3 domain protein
BS21228_RS09440	COG2249	NAD(P)H dehydrogenase (quinone) activity
BS21228_RS09445	COG3527	Alpha-acetolactate decarboxylase
BS21228_RS09450	COG0028	Belongs to the TPP enzyme family
BS21228_RS09455	COG0583	DNA-binding transcription factor activity
BS21228_RS09460	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BS21228_RS09475	COG5337	Spore coat protein CotH
BS21228_RS09485	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BS21228_RS09495	COG0405	Gamma-glutamyltransferase
BS21228_RS09500	COG1522	sequence-specific DNA binding
BS21228_RS09505	COG2059	Chromate
BS21228_RS09510	COG2059	Chromate
BS21228_RS09520	COG0655	NAD(P)H dehydrogenase (quinone) activity
BS21228_RS09525	COG0583	DNA-binding transcription factor activity
BS21228_RS09555	COG5444	nuclease activity
BS21228_RS09575	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BS21228_RS09580	COG4464	protein tyrosine phosphatase activity
BS21228_RS09585	COG0489	protein tyrosine kinase activity
BS21228_RS09590	COG3944	biosynthesis protein
BS21228_RS09600	COG4715	Zinc finger, swim domain protein
BS21228_RS09605	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BS21228_RS09615	COG0561	phosphatase activity
BS21228_RS09620	COG1349	DNA-binding transcription factor activity
BS21228_RS09625	COG0629	single-stranded DNA binding
BS21228_RS09640	COG3764	Sortase (surface protein transpeptidase)
BS21228_RS09645	COG2972	Histidine kinase
BS21228_RS09645	COG0745	RESPONSE REGULATOR receiver
BS21228_RS09650	COG1970	mechanosensitive ion channel activity
BS21228_RS09655	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BS21228_RS09660	COG0457	Tetratricopeptide repeat
BS21228_RS09665	COG4786	Flagellar basal body rod
BS21228_RS09670	COG4786	Flagellar basal body rod
BS21228_RS09675	COG1077	Cell shape determining protein MreB Mrl
BS21228_RS09680	COG1609	Transcriptional regulator
BS21228_RS09690	COG1846	Transcriptional regulator
BS21228_RS09695	COG2814	Major facilitator Superfamily
BS21228_RS09700	COG3420	alginic acid biosynthetic process
BS21228_RS09705	COG1953	Uracil, thiamine, allantoin
BS21228_RS09710	COG0477	Major facilitator Superfamily
BS21228_RS09715	COG1335	isochorismatase
BS21228_RS09725	COG0004	ammonium transporteR
BS21228_RS09730	COG0347	Belongs to the P(II) protein family
BS21228_RS09735	COG0671	phosphoesterase, PA-phosphatase related
BS21228_RS09745	COG0739	heme binding
BS21228_RS09750	COG1247	-acetyltransferase
BS21228_RS09760	COG2089	acid synthase
BS21228_RS09770	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BS21228_RS09775	COG0789	Transcriptional regulator
BS21228_RS09785	COG2910	NAD(P)H-binding
BS21228_RS09790	COG1959	2 iron, 2 sulfur cluster binding
BS21228_RS09795	COG0804	urea catabolic process
BS21228_RS09800	COG0832	Belongs to the urease beta subunit family
BS21228_RS09805	COG0831	urea catabolic process
BS21228_RS09820	COG3237	CsbD-like
BS21228_RS09825	COG1994	Peptidase M50
BS21228_RS09830	COG0457	Tetratricopeptide repeat
BS21228_RS09840	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BS21228_RS09845	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BS21228_RS09855	COG2304	oxidoreductase activity
BS21228_RS09865	COG2304	oxidoreductase activity
BS21228_RS09870	COG2385	sporulation resulting in formation of a cellular spore
BS21228_RS09875	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BS21228_RS09885	COG4836	Membrane
BS21228_RS09895	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BS21228_RS09900	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BS21228_RS09905	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BS21228_RS09910	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BS21228_RS09915	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BS21228_RS09920	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BS21228_RS09930	COG0356	it plays a direct role in the translocation of protons across the membrane
BS21228_RS09940	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BS21228_RS09945	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BS21228_RS09950	COG4475	Protein of unknown function (DUF436)
BS21228_RS09955	COG0698	ribose 5-phosphate isomerase
BS21228_RS09960	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BS21228_RS09965	COG1971	Probably functions as a manganese efflux pump
BS21228_RS09970	COG0009	L-threonylcarbamoyladenylate synthase
BS21228_RS09975	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BS21228_RS09995	COG2890	protein-(glutamine-N5) methyltransferase activity
BS21228_RS10000	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BS21228_RS10005	COG0346	lactoylglutathione lyase activity
BS21228_RS10010	COG0789	Transcriptional regulator
BS21228_RS10015	COG0679	Auxin Efflux Carrier
BS21228_RS10020	COG0281	malic enzyme
BS21228_RS10025	COG1435	thymidine kinase activity
BS21228_RS10035	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BS21228_RS10040	COG1494	fructose-1,6-bisphosphatase
BS21228_RS10045	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BS21228_RS10050	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BS21228_RS10055	COG0191	fructose-bisphosphate aldolase activity
BS21228_RS10060	COG2204	response regulator
BS21228_RS10065	COG4821	SIS domain
BS21228_RS10070	COG0504	CTP synthase activity
BS21228_RS10075	COG3343	RNA polymerase activity
BS21228_RS10080	COG1960	acyl-CoA dehydrogenase activity
BS21228_RS10085	COG2181	nitrate reductase activity
BS21228_RS10085	COG0247	lactate metabolic process
BS21228_RS10090	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BS21228_RS10095	COG4294	response to UV
BS21228_RS10105	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BS21228_RS10115	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BS21228_RS10125	COG2181	nitrate reductase activity
BS21228_RS10130	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BS21228_RS10135	COG1140	nitrate reductase beta subunit
BS21228_RS10140	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BS21228_RS10145	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BS21228_RS10155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BS21228_RS10160	COG2223	nitrite transmembrane transporter activity
BS21228_RS10165	COG0018	arginyl-trna synthetase
BS21228_RS10170	COG4506	Protein conserved in bacteria
BS21228_RS10185	COG0535	radical SAM domain protein
BS21228_RS10195	COG1131	(ABC) transporter
BS21228_RS10200	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BS21228_RS10205	COG0612	Peptidase, M16
BS21228_RS10210	COG0612	Peptidase, M16
BS21228_RS10220	COG3391	amine dehydrogenase activity
BS21228_RS10225	COG3391	amine dehydrogenase activity
BS21228_RS10235	COG0457	Tetratricopeptide repeat
BS21228_RS10245	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BS21228_RS10250	COG0010	Belongs to the arginase family
BS21228_RS10255	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BS21228_RS10260	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BS21228_RS10275	COG1994	Peptidase M50
BS21228_RS10280	COG1942	4-Oxalocrotonate Tautomerase
BS21228_RS10285	COG1846	Transcriptional regulator
BS21228_RS10290	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BS21228_RS10295	COG0477	Major facilitator Superfamily
BS21228_RS10300	COG1959	2 iron, 2 sulfur cluster binding
BS21228_RS10305	COG3465	dGTPase activity
BS21228_RS10310	COG1078	dGTPase activity
BS21228_RS10315	COG4844	belongs to the
BS21228_RS10325	COG0697	spore germination
BS21228_RS10330	COG0095	Lipoate-protein ligase
BS21228_RS10335	COG0583	DNA-binding transcription factor activity
BS21228_RS10340	COG0280	phosphate acetyltransferase
BS21228_RS10345	COG3253	May function as heme-dependent peroxidase
BS21228_RS10350	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_RS10355	COG0436	Aminotransferase
BS21228_RS10360	COG2814	Major facilitator Superfamily
BS21228_RS10365	COG0151	Belongs to the GarS family
BS21228_RS10370	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_RS10375	COG1917	Cupin 2, conserved barrel domain protein
BS21228_RS10380	COG0077	Prephenate dehydratase
BS21228_RS10385	COG2814	Major facilitator Superfamily
BS21228_RS10390	COG0833	amino acid
BS21228_RS10395	COG4187	Peptidase family M20/M25/M40
BS21228_RS10400	COG1012	belongs to the aldehyde dehydrogenase family
BS21228_RS10405	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BS21228_RS10415	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
BS21228_RS10420	COG1091	dTDP-4-dehydrorhamnose reductase activity
BS21228_RS10425	COG1088	dTDP-glucose 4,6-dehydratase activity
BS21228_RS10430	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BS21228_RS10435	COG3980	spore coat polysaccharide biosynthesis protein
BS21228_RS10440	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
BS21228_RS10445	COG2089	acid synthase
BS21228_RS10450	COG0456	acetyltransferase
BS21228_RS10455	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BS21228_RS10460	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BS21228_RS10465	COG0463	Glycosyl transferase, family 2
BS21228_RS10480	COG2363	Small membrane protein
BS21228_RS10485	COG2233	PERMEase
BS21228_RS10495	COG1012	belongs to the aldehyde dehydrogenase family
BS21228_RS10500	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BS21228_RS10505	COG1216	Glycosyl transferase, family 2
BS21228_RS10510	COG0351	phosphomethylpyrimidine kinase
BS21228_RS10520	COG1621	beta-fructofuranosidase activity
BS21228_RS10525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS21228_RS10525	COG1263	PTS System
BS21228_RS10530	COG2116	formate transmembrane transporter activity
BS21228_RS10545	COG1404	Belongs to the peptidase S8 family
BS21228_RS10550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BS21228_RS10555	COG0778	Nitroreductase
BS21228_RS10560	COG0772	Belongs to the SEDS family
BS21228_RS10575	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BS21228_RS10580	COG1845	cytochrome c oxidase, subunit III
BS21228_RS10585	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BS21228_RS10590	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BS21228_RS10595	COG2261	transglycosylase associated protein
BS21228_RS10600	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BS21228_RS10605	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BS21228_RS10610	COG2246	polysaccharide biosynthetic process
BS21228_RS10615	COG1309	transcriptional regulator
BS21228_RS10625	COG3162	membrane
BS21228_RS10630	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BS21228_RS10635	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BS21228_RS10640	COG2837	iron assimilation
BS21228_RS10645	COG2822	iron ion transport
BS21228_RS10650	COG0672	)-iron permease
BS21228_RS10655	COG0352	thiamine-phosphate diphosphorylase activity
BS21228_RS10660	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BS21228_RS10665	COG0583	DNA-binding transcription factor activity
BS21228_RS10670	COG1380	Effector of murein hydrolase LrgA
BS21228_RS10675	COG1346	cytolysis
BS21228_RS10680	COG2814	Major facilitator Superfamily
BS21228_RS10685	COG4895	conserved protein (DUF2196)
BS21228_RS10690	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BS21228_RS10695	COG0346	lactoylglutathione lyase activity
BS21228_RS10705	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BS21228_RS10715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS21228_RS10715	COG1263	PTS System
BS21228_RS10720	COG3711	transcriptional antiterminator
BS21228_RS10725	COG1442	glycosyl transferase family 8
BS21228_RS10730	COG5522	Integral membrane protein (intg_mem_TP0381)
BS21228_RS10735	COG1846	Transcriptional regulator
BS21228_RS10740	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BS21228_RS10745	COG2234	aminopeptidase activity
BS21228_RS10750	COG2357	RelA SpoT domain protein
BS21228_RS10760	COG1575	Belongs to the MenA family. Type 1 subfamily
BS21228_RS10775	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BS21228_RS10780	COG1696	Membrane protein involved in D-alanine export
BS21228_RS10785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BS21228_RS10790	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BS21228_RS10800	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BS21228_RS10805	COG1486	melibiose metabolic process
BS21228_RS10810	COG1447	Phosphotransferase system cellobiose-specific component IIA
BS21228_RS10815	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BS21228_RS10820	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BS21228_RS10825	COG3711	transcriptional antiterminator
BS21228_RS10825	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS21228_RS10835	COG2094	Belongs to the DNA glycosylase MPG family
BS21228_RS10840	COG0753	catalase activity
BS21228_RS10845	COG2814	Major facilitator Superfamily
BS21228_RS10850	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BS21228_RS10855	COG1131	(ABC) transporter
BS21228_RS10875	COG1595	DNA-templated transcription, initiation
BS21228_RS10880	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BS21228_RS10885	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BS21228_RS10890	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BS21228_RS10895	COG4988	ABC transporter
BS21228_RS10900	COG1294	oxidase, subunit
BS21228_RS10905	COG1271	oxidase subunit
BS21228_RS10910	COG3493	citrate carrier protein
BS21228_RS10915	COG0501	Belongs to the peptidase M48B family
BS21228_RS10925	COG0726	polysaccharide deacetylase
BS21228_RS10930	COG3842	ATPase activity
BS21228_RS10935	COG2508	Transcriptional regulator
BS21228_RS10940	COG1012	belongs to the aldehyde dehydrogenase family
BS21228_RS10945	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BS21228_RS10955	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BS21228_RS10965	COG4585	Histidine kinase
BS21228_RS10970	COG2197	response regulator
BS21228_RS10975	COG2195	Cleaves the N-terminal amino acid of tripeptides
BS21228_RS10985	COG4894	glucomannan catabolic process
BS21228_RS10990	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BS21228_RS10995	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BS21228_RS11000	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_RS11005	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BS21228_RS11010	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BS21228_RS11015	COG2610	gluconate transmembrane transporter activity
BS21228_RS11020	COG0500	methyltransferase
BS21228_RS11025	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BS21228_RS11040	COG0753	catalase activity
BS21228_RS11040	COG0693	protein deglycase activity
BS21228_RS11045	COG2851	Citrate transporter
BS21228_RS11050	COG2273	Hydrolase Family 16
BS21228_RS11055	COG3711	transcriptional antiterminator
BS21228_RS11070	COG2270	Major facilitator Superfamily
BS21228_RS11075	COG0513	Belongs to the DEAD box helicase family
BS21228_RS11080	COG3401	FG-GAP repeat protein
BS21228_RS11080	COG2755	lipolytic protein G-D-S-L family
BS21228_RS11210	COG0589	response to stress
BS21228_RS11220	COG2190	(PTS) system
BS21228_RS11220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS21228_RS11220	COG1263	PTS System
BS21228_RS11240	COG5444	nuclease activity
BS21228_RS11260	COG0494	nUDIX hydrolase
BS21228_RS11265	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BS21228_RS11270	COG3507	Belongs to the glycosyl hydrolase 43 family
BS21228_RS11285	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BS21228_RS11290	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BS21228_RS11295	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BS21228_RS11300	COG2390	Transcriptional regulator
BS21228_RS11310	COG3192	ethanolamine utilization protein
BS21228_RS11315	COG2079	MmgE PrpD family protein
BS21228_RS11320	COG1473	amidohydrolase
BS21228_RS11325	COG1126	abc transporter atp-binding protein
BS21228_RS11330	COG0765	amino acid transport
BS21228_RS11335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BS21228_RS11340	COG0456	acetyltransferase
BS21228_RS11345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BS21228_RS11350	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BS21228_RS11355	COG0561	phosphatase activity
BS21228_RS11385	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS21228_RS11390	COG5294	Protein conserved in bacteria
BS21228_RS11405	COG2205	protein histidine kinase activity
BS21228_RS11410	COG0745	RESPONSE REGULATOR receiver
BS21228_RS11415	COG0191	fructose-bisphosphate aldolase activity
BS21228_RS11420	COG1082	Xylose isomerase domain protein TIM barrel
BS21228_RS11425	COG1082	Xylose isomerase domain protein TIM barrel
BS21228_RS11430	COG0673	inositol 2-dehydrogenase activity
BS21228_RS11435	COG2814	Major facilitator Superfamily
BS21228_RS11440	COG1082	Xylose isomerase domain protein TIM barrel
BS21228_RS11445	COG3962	Belongs to the TPP enzyme family
BS21228_RS11450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BS21228_RS11470	COG1349	DNA-binding transcription factor activity
BS21228_RS11475	COG0667	Aldo Keto reductase
BS21228_RS11505	COG0326	Molecular chaperone. Has ATPase activity
BS21228_RS11570	COG1917	Cupin 2, conserved barrel domain protein
BS21228_RS11575	COG1309	transcriptional regulator
BS21228_RS11580	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_RS11585	COG1846	Transcriptional regulator
BS21228_RS11590	COG1380	Effector of murein hydrolase LrgA
BS21228_RS11595	COG1346	cytolysis
BS21228_RS11600	COG5039	Polysaccharide pyruvyl transferase
BS21228_RS11605	COG1929	Belongs to the glycerate kinase type-1 family
BS21228_RS11610	COG1802	Transcriptional regulator
BS21228_RS11615	COG1070	Carbohydrate kinase
BS21228_RS11620	COG2610	gluconate transmembrane transporter activity
BS21228_RS11625	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BS21228_RS11630	COG0450	alkyl hydroperoxide reductase
BS21228_RS11635	COG3634	alkyl hydroperoxide reductase activity
BS21228_RS11640	COG2723	6-phospho-beta-galactosidase activity
BS21228_RS11655	COG2188	Transcriptional regulator
BS21228_RS11665	COG1131	(ABC) transporter
BS21228_RS11670	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
BS21228_RS11685	COG0071	Belongs to the small heat shock protein (HSP20) family
BS21228_RS11720	COG0210	DNA helicase
BS21228_RS11750	COG2963	transposase activity
BS21228_RS11785	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BS21228_RS11800	COG1063	alcohol dehydrogenase
BS21228_RS11820	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
BS21228_RS11825	COG0456	acetyltransferase
BS21228_RS11830	COG0457	Tetratricopeptide repeat
BS21228_RS11840	COG0010	Belongs to the arginase family
BS21228_RS11845	COG0833	amino acid
BS21228_RS11850	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BS21228_RS11870	COG5658	integral membrane protein
BS21228_RS11875	COG0640	Transcriptional regulator
BS21228_RS11880	COG3829	transcription factor binding
BS21228_RS11890	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BS21228_RS11895	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BS21228_RS11900	COG4853	Protein conserved in bacteria
BS21228_RS11905	COG4863	YycH protein
BS21228_RS11910	COG5002	protein histidine kinase activity
BS21228_RS11915	COG0745	RESPONSE REGULATOR receiver
BS21228_RS11945	COG0346	lactoylglutathione lyase activity
BS21228_RS11950	COG0305	Participates in initiation and elongation during chromosome replication
BS21228_RS11965	COG3093	addiction module antidote protein HigA
BS21228_RS11970	COG2807	transmembrane transport
BS21228_RS11975	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BS21228_RS11980	COG0359	binds to the 23S rRNA
BS21228_RS11985	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BS21228_RS11990	COG4241	membrane
BS21228_RS12005	COG1733	regulation of RNA biosynthetic process
BS21228_RS12010	COG1227	inorganic diphosphatase activity
BS21228_RS12025	COG2271	Major facilitator Superfamily
BS21228_RS12030	COG4978	Transcriptional regulator
BS21228_RS12030	COG0789	Transcriptional regulator
BS21228_RS12040	COG4319	ketosteroid isomerase
BS21228_RS12045	COG1357	PFAM Pentapeptide repeats (8 copies)
BS21228_RS12060	COG1846	Transcriptional regulator
BS21228_RS12065	COG2153	protein acetylation
BS21228_RS12070	COG2364	Membrane
BS21228_RS12075	COG0456	acetyltransferase
BS21228_RS12080	COG2315	Protein conserved in bacteria
BS21228_RS12085	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BS21228_RS12090	COG1331	Highly conserved protein containing a thioredoxin domain
BS21228_RS12095	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
BS21228_RS12100	COG1331	Highly conserved protein containing a thioredoxin domain
BS21228_RS12105	COG1266	CAAX protease self-immunity
BS21228_RS12110	COG2814	Major facilitator Superfamily
BS21228_RS12110	COG0477	Major facilitator Superfamily
BS21228_RS12115	COG0346	lactoylglutathione lyase activity
BS21228_RS12120	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BS21228_RS12125	COG0542	response to heat
BS21228_RS12140	COG0708	Exodeoxyribonuclease III
BS21228_RS12145	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BS21228_RS12150	COG0629	single-stranded DNA binding
BS21228_RS12155	COG0360	Binds together with S18 to 16S ribosomal RNA
BS21228_RS12160	COG0012	GTP binding
BS21228_RS12165	COG0243	molybdopterin cofactor binding
BS21228_RS12170	COG4481	Protein conserved in bacteria
BS21228_RS12175	COG3949	Membrane
BS21228_RS12185	COG1475	DNA binding
BS21228_RS12190	COG1192	Involved in chromosome partitioning
BS21228_RS12200	COG1475	DNA binding
BS21228_RS12205	COG0357	Ribosomal RNA small subunit methyltransferase G
BS21228_RS12210	COG0445	tRNA wobble uridine modification
BS21228_RS12215	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BS21228_RS12220	COG1847	R3H domain protein
BS21228_RS12225	COG0706	membrane insertase activity
BS21228_RS12230	COG0594	ribonuclease P activity
BS21228_RS12240	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BS21228_RS12245	COG0592	DNA-directed DNA polymerase activity
BS21228_RS12250	COG2501	S4 domain
BS21228_RS12255	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BS21228_RS12265	COG0187	DNA topoisomerase II activity
BS21228_RS12270	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BS21228_RS12305	COG0517	IMP dehydrogenase activity
BS21228_RS12305	COG0516	GMP reductase activity
BS21228_RS12310	COG1686	Belongs to the peptidase S11 family
BS21228_RS12315	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BS21228_RS12320	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BS21228_RS12325	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BS21228_RS12335	COG1428	Deoxynucleoside kinase
BS21228_RS12340	COG1428	Deoxynucleoside kinase
BS21228_RS12345	COG1388	LysM domain
BS21228_RS12345	COG3858	chitin binding
BS21228_RS12350	COG1335	isochorismatase
BS21228_RS12355	COG0590	tRNA wobble adenosine to inosine editing
BS21228_RS12365	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BS21228_RS12370	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BS21228_RS12375	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BS21228_RS12420	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
BS21228_RS12425	COG3853	Toxic anion resistance protein (TelA)
BS21228_RS12430	COG1982	Orn Lys Arg decarboxylase major
BS21228_RS12435	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BS21228_RS12440	COG3870	Protein conserved in bacteria
BS21228_RS12445	COG1728	Protein conserved in bacteria
BS21228_RS12450	COG0470	DNA polymerase III
BS21228_RS12455	COG1774	PSP1 C-terminal conserved region
BS21228_RS12460	COG4467	Involved in initiation control of chromosome replication
BS21228_RS12465	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BS21228_RS12470	COG2827	Endonuclease containing a URI domain
BS21228_RS12475	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BS21228_RS12480	COG2002	toxin-antitoxin pair type II binding
BS21228_RS12485	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BS21228_RS12485	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BS21228_RS12490	COG0084	hydrolase, TatD family'
BS21228_RS12495	COG3583	domain protein
BS21228_RS12495	COG3584	3D domain protein
BS21228_RS12500	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BS21228_RS12505	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BS21228_RS12515	COG4466	Protein conserved in bacteria
BS21228_RS12525	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BS21228_RS12530	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BS21228_RS12535	COG0251	oxidation-reduction process
BS21228_RS12540	COG2088	sporulation resulting in formation of a cellular spore
BS21228_RS12545	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BS21228_RS12550	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BS21228_RS12555	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BS21228_RS12560	COG0193	aminoacyl-tRNA hydrolase activity
BS21228_RS12570	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BS21228_RS12575	COG2002	toxin-antitoxin pair type II binding
BS21228_RS12580	COG2244	polysaccharide biosynthetic process
BS21228_RS12585	COG3956	TIGRFAM MazG family protein
BS21228_RS12590	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BS21228_RS12605	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BS21228_RS12610	COG1098	S1 RNA binding domain
BS21228_RS12625	COG2208	phosphoserine phosphatase activity
BS21228_RS12630	COG2304	oxidoreductase activity
BS21228_RS12635	COG0515	serine threonine protein kinase
BS21228_RS12640	COG0037	tRNA processing
BS21228_RS12645	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BS21228_RS12650	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BS21228_RS12655	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BS21228_RS12660	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BS21228_RS12665	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BS21228_RS12670	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BS21228_RS12675	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BS21228_RS12680	COG0512	Glutamine amidotransferase of anthranilate synthase
BS21228_RS12685	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BS21228_RS12690	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BS21228_RS12695	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BS21228_RS12700	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BS21228_RS12705	COG1396	sequence-specific DNA binding
BS21228_RS12710	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BS21228_RS12715	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BS21228_RS12795	COG4463	regulation of RNA biosynthetic process
BS21228_RS12800	COG3880	PFAM UvrB UvrC protein
BS21228_RS12805	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BS21228_RS12810	COG0542	response to heat
BS21228_RS12815	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BS21228_RS12820	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BS21228_RS12825	COG4956	integral membrane protein (PIN domain superfamily)
BS21228_RS12830	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BS21228_RS12835	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BS21228_RS12840	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BS21228_RS12850	COG1045	serine acetyltransferase
BS21228_RS12855	COG0215	cysteine-tRNA ligase activity
BS21228_RS12860	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BS21228_RS12865	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BS21228_RS12870	COG3688	RNA-binding protein containing a PIN domain
BS21228_RS12875	COG1595	DNA-templated transcription, initiation
BS21228_RS12885	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BS21228_RS12890	COG0250	Participates in transcription elongation, termination and antitermination
BS21228_RS12900	COG0081	regulation of translation
BS21228_RS12905	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BS21228_RS12915	COG2813	Specifically methylates the guanine in position
BS21228_RS12920	COG0085	RNA polymerase activity
BS21228_RS12925	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BS21228_RS12930	COG1358	cellular component organization or biogenesis
BS21228_RS12935	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BS21228_RS12940	COG0049	tRNA binding
BS21228_RS12945	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BS21228_RS12950	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BS21228_RS12955	COG0596	Alpha beta hydrolase
BS21228_RS12965	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BS21228_RS12970	COG0088	Forms part of the polypeptide exit tunnel
BS21228_RS12980	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BS21228_RS12995	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BS21228_RS13000	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BS21228_RS13010	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BS21228_RS13015	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BS21228_RS13025	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BS21228_RS13035	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BS21228_RS13040	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BS21228_RS13045	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BS21228_RS13050	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BS21228_RS13060	COG0200	Binds to the 23S rRNA
BS21228_RS13065	COG0201	protein transport
BS21228_RS13070	COG0563	adenylate kinase activity
BS21228_RS13075	COG0024	Methionine aminopeptidase
BS21228_RS13080	COG2163	COG2163 Ribosomal protein L14E L6E L27E
BS21228_RS13090	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BS21228_RS13095	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BS21228_RS13100	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BS21228_RS13105	COG0202	RNA polymerase activity
BS21228_RS13110	COG0203	ribosomal protein L17
BS21228_RS13115	COG1122	ATPase activity
BS21228_RS13120	COG1122	ATPase activity
BS21228_RS13125	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BS21228_RS13130	COG0101	tRNA pseudouridine synthase activity
BS21228_RS13135	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BS21228_RS13140	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BS21228_RS13150	COG2226	methyltransferase
BS21228_RS13160	COG0860	N-Acetylmuramoyl-L-alanine amidase
BS21228_RS13165	COG0489	protein tyrosine kinase activity
BS21228_RS13175	COG2194	sulfuric ester hydrolase activity
BS21228_RS13180	COG0726	polysaccharide deacetylase
BS21228_RS13265	COG0659	secondary active sulfate transmembrane transporter activity
BS21228_RS13270	COG0385	Bile acid
BS21228_RS13275	COG2819	hydrolase of the alpha beta superfamily
BS21228_RS13280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS21228_RS13285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS21228_RS13290	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS21228_RS13295	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS21228_RS13295	COG2207	Transcriptional regulator
BS21228_RS13300	COG3876	Protein conserved in bacteria
BS21228_RS13305	COG1472	Belongs to the glycosyl hydrolase 3 family
BS21228_RS13310	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BS21228_RS13315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS21228_RS13315	COG1263	PTS System
BS21228_RS13320	COG1737	Transcriptional regulator
BS21228_RS13325	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BS21228_RS13330	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS21228_RS13335	COG1683	Conserved Protein
BS21228_RS13365	COG1595	DNA-templated transcription, initiation
BS21228_RS13370	COG5662	AntiSigma factor
BS21228_RS13375	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BS21228_RS13380	COG4856	YbbR-like protein
BS21228_RS13385	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BS21228_RS13395	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BS21228_RS13405	COG2169	Transcriptional regulator
BS21228_RS13410	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BS21228_RS13415	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BS21228_RS13420	COG3002	Belongs to the UPF0753 family
BS21228_RS13425	COG0288	reversible hydration of carbon dioxide
BS21228_RS13435	COG5609	conserved protein (DUF2294)
BS21228_RS13445	COG0642	Histidine kinase
BS21228_RS13455	COG0515	serine threonine protein kinase
BS21228_RS13470	COG1113	amino acid transport
BS21228_RS13485	COG2602	Beta-lactamase
BS21228_RS13490	COG2124	cytochrome p450
BS21228_RS13500	COG0531	amino acid
BS21228_RS13505	COG0584	glycerophosphoryl diester phosphodiesterase
BS21228_RS13510	COG2271	Major facilitator Superfamily
BS21228_RS13525	COG0456	acetyltransferase
BS21228_RS13525	COG1846	Transcriptional regulator
BS21228_RS13545	COG3409	Peptidoglycan-binding domain 1 protein
BS21228_RS13550	COG0697	spore germination
BS21228_RS13555	COG1917	Cupin 2, conserved barrel domain protein
BS21228_RS13555	COG2207	Transcriptional regulator
BS21228_RS13580	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BS21228_RS13585	COG3591	Belongs to the peptidase S1B family
BS21228_RS13595	COG0596	Alpha beta hydrolase
BS21228_RS13600	COG1183	phosphatidylcholine synthase activity
BS21228_RS13605	COG0586	Pfam SNARE associated Golgi protein
BS21228_RS13610	COG0688	phosphatidylethanolamine metabolic process
BS21228_RS13620	COG2312	Erythromycin esterase
BS21228_RS13625	COG2207	Transcriptional regulator
BS21228_RS13630	COG1054	Belongs to the UPF0176 family
BS21228_RS13635	COG1301	dicarboxylic acid transport
BS21228_RS13640	COG2190	(PTS) system
BS21228_RS13640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS21228_RS13640	COG1263	PTS System
BS21228_RS13645	COG0363	glucosamine-6-phosphate deaminase activity
BS21228_RS13650	COG2188	Transcriptional regulator
BS21228_RS13660	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BS21228_RS13665	COG0833	amino acid
BS21228_RS13670	COG2040	homocysteine
BS21228_RS13685	COG2066	Belongs to the glutaminase family
BS21228_RS13690	COG4191	Histidine kinase
BS21228_RS13695	COG0784	Response regulator, receiver
BS21228_RS13705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BS21228_RS13710	COG1012	belongs to the aldehyde dehydrogenase family
BS21228_RS13715	COG2271	Major facilitator Superfamily
BS21228_RS13720	COG4948	Mandelate Racemase Muconate Lactonizing
BS21228_RS13725	COG2186	Transcriptional regulator
BS21228_RS13730	COG2721	sulfolactate sulfo-lyase activity
BS21228_RS13735	COG3173	Aminoglycoside phosphotransferase
BS21228_RS13745	COG0697	spore germination
BS21228_RS13750	COG0745	RESPONSE REGULATOR receiver
BS21228_RS13755	COG2205	protein histidine kinase activity
BS21228_RS13760	COG1131	(ABC) transporter
BS21228_RS13775	COG3773	Cell wall hydrolase
BS21228_RS13780	COG2304	oxidoreductase activity
BS21228_RS13790	COG3540	Alkaline phosphatase
BS21228_RS13795	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BS21228_RS13800	COG0805	protein transport
BS21228_RS13805	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BS21228_RS13810	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BS21228_RS13815	COG0477	Major facilitator Superfamily
BS21228_RS13820	COG1309	transcriptional regulator
BS21228_RS13825	COG0252	asparaginase activity
BS21228_RS13830	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BS21228_RS13835	COG1714	RDD family
BS21228_RS13840	COG1405	negative regulation of cell septum assembly
BS21228_RS13840	COG3012	SEC-C Motif Domain Protein
BS21228_RS13850	COG3279	Response regulator of the LytR AlgR family
BS21228_RS13860	COG1668	transmembrane transport
BS21228_RS13865	COG0667	Aldo Keto reductase
BS21228_RS13875	COG1595	DNA-templated transcription, initiation
BS21228_RS13880	COG1595	DNA-templated transcription, initiation
BS21228_RS13885	COG1876	peptidase activity
BS21228_RS13895	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_RS13900	COG0366	Alpha amylase catalytic
BS21228_RS13905	COG0803	Belongs to the bacterial solute-binding protein 9 family
BS21228_RS13910	COG1121	(ABC) transporter
BS21228_RS13915	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BS21228_RS13925	COG2310	stress, protein
BS21228_RS13930	COG2310	stress, protein
BS21228_RS13935	COG2310	stress, protein
BS21228_RS13940	COG0861	Integral membrane protein TerC family
BS21228_RS13950	COG3853	Toxic anion resistance protein (TelA)
BS21228_RS13960	COG0477	Major facilitator Superfamily
BS21228_RS13965	COG2814	Major facilitator Superfamily
BS21228_RS13970	COG0640	Transcriptional regulator
BS21228_RS13975	COG4175	Glycine betaine
BS21228_RS13975	COG0517	IMP dehydrogenase activity
BS21228_RS13980	COG4176	ABC-type proline glycine betaine transport system permease component
BS21228_RS13985	COG2113	Glycine betaine
BS21228_RS13990	COG1473	amidohydrolase
BS21228_RS13995	COG1288	antiporter activity
BS21228_RS14010	COG0039	L-malate dehydrogenase activity
BS21228_RS14025	COG3403	YqcI/YcgG family
BS21228_RS14040	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BS21228_RS14045	COG1660	Displays ATPase and GTPase activities
BS21228_RS14055	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BS21228_RS14065	COG2226	methyltransferase
BS21228_RS14070	COG0583	DNA-binding transcription factor activity
BS21228_RS14075	COG3458	cephalosporin-C deacetylase activity
BS21228_RS14080	COG3541	Predicted nucleotidyltransferase
BS21228_RS14085	COG0506	proline dehydrogenase activity
BS21228_RS14090	COG1012	belongs to the aldehyde dehydrogenase family
BS21228_RS14095	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BS21228_RS14100	COG2508	Transcriptional regulator
BS21228_RS14105	COG3689	TIGRFAM TIGR03943 family protein
BS21228_RS14110	COG0701	Predicted permease
BS21228_RS14115	COG2267	carboxylic ester hydrolase activity
BS21228_RS14120	COG0492	ferredoxin-NADP+ reductase activity
BS21228_RS14125	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BS21228_RS14125	COG1587	Uroporphyrinogen-III synthase
BS21228_RS14130	COG2146	nitrite reductase [NAD(P)H] activity
BS21228_RS14135	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BS21228_RS14140	COG0243	molybdopterin cofactor binding
BS21228_RS14145	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BS21228_RS14150	COG2223	nitrite transmembrane transporter activity
BS21228_RS14160	COG1376	ErfK ybiS ycfS ynhG family protein
BS21228_RS14175	COG0765	amino acid transport
BS21228_RS14180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BS21228_RS14190	COG1714	RDD family
BS21228_RS14200	COG1846	Transcriptional regulator
BS21228_RS14215	COG2723	6-phospho-beta-galactosidase activity
BS21228_RS14225	COG3209	COG3209 Rhs family protein
BS21228_RS14235	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BS21228_RS14240	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BS21228_RS14245	COG1733	regulation of RNA biosynthetic process
BS21228_RS14250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BS21228_RS14255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BS21228_RS14260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BS21228_RS14265	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
BS21228_RS14270	COG2814	Major facilitator Superfamily
BS21228_RS14280	COG0697	spore germination
BS21228_RS14285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS21228_RS14295	COG2364	Membrane
BS21228_RS14300	COG1126	abc transporter atp-binding protein
BS21228_RS14305	COG0765	amino acid transport
BS21228_RS14310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BS21228_RS14315	COG0583	DNA-binding transcription factor activity
BS21228_RS14320	COG0163	prenyltransferase activity
BS21228_RS14325	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BS21228_RS14340	COG0596	Alpha beta hydrolase
BS21228_RS14345	COG3104	oligopeptide transport
BS21228_RS14350	COG5434	Belongs to the glycosyl hydrolase 28 family
BS21228_RS14360	COG0697	spore germination
BS21228_RS14370	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BS21228_RS14375	COG1136	(ABC) transporter
BS21228_RS14380	COG0577	efflux transmembrane transporter activity
BS21228_RS14385	COG0745	RESPONSE REGULATOR receiver
BS21228_RS14390	COG5002	protein histidine kinase activity
BS21228_RS14390	COG3850	Histidine kinase
BS21228_RS14395	COG0457	Tetratricopeptide repeat
BS21228_RS14415	COG0527	aspartate kinase activity
BS21228_RS14420	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS21228_RS14425	COG4605	iron ion homeostasis
BS21228_RS14430	COG4604	ABC transporter, ATP-binding protein
BS21228_RS14435	COG4607	ABC-type enterochelin transport system periplasmic component
BS21228_RS14445	COG2814	Major facilitator Superfamily
BS21228_RS14450	COG1309	transcriptional regulator
BS21228_RS14455	COG0778	Nitroreductase
BS21228_RS14460	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BS21228_RS14465	COG0640	Transcriptional regulator
BS21228_RS14470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS21228_RS14475	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BS21228_RS14480	COG1012	belongs to the aldehyde dehydrogenase family
BS21228_RS14485	COG4975	Glucose uptake
BS21228_RS14490	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_RS14495	COG4549	nuclear export factor GLE1
BS21228_RS14500	COG1276	copper resistance
BS21228_RS14500	COG2372	response to copper ion
BS21228_RS14505	COG1349	DNA-binding transcription factor activity
BS21228_RS14515	COG2213	PTS system mannitol-specific
BS21228_RS14520	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS21228_RS14525	COG0246	Mannitol dehydrogenase
BS21228_RS14530	COG0473	3-isopropylmalate dehydrogenase activity
BS21228_RS14535	COG0681	Belongs to the peptidase S26 family
BS21228_RS14545	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BS21228_RS14555	COG0561	phosphatase activity
BS21228_RS14560	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BS21228_RS14565	COG1914	H( )-stimulated, divalent metal cation uptake system
BS21228_RS14570	COG4336	lyase activity
BS21228_RS14575	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BS21228_RS14580	COG1984	allophanate hydrolase subunit 2
BS21228_RS14585	COG1414	Transcriptional regulator
BS21228_RS14590	COG2755	lipolytic protein G-D-S-L family
BS21228_RS14600	COG2329	Antibiotic biosynthesis monooxygenase
BS21228_RS14605	COG0768	penicillin binding
BS21228_RS14610	COG4989	oxidoreductase activity
BS21228_RS14615	COG3711	transcriptional antiterminator
BS21228_RS14620	COG0318	PFAM AMP-dependent synthetase and ligase
BS21228_RS14625	COG2226	methyltransferase
BS21228_RS14630	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_RS14635	COG1917	Cupin 2, conserved barrel domain protein
BS21228_RS14640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS21228_RS14645	COG3871	stress protein (general stress protein 26)
BS21228_RS14655	COG2814	Major facilitator Superfamily
BS21228_RS14660	COG1522	sequence-specific DNA binding
BS21228_RS14665	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BS21228_RS14665	COG0551	DNA topoisomerase type I activity
BS21228_RS14670	COG0494	nUDIX hydrolase
BS21228_RS14675	COG0028	Belongs to the TPP enzyme family
BS21228_RS14705	COG1914	H( )-stimulated, divalent metal cation uptake system
BS21228_RS14710	COG2261	transglycosylase associated protein
BS21228_RS14715	COG4876	unkown
BS21228_RS14720	COG2217	Heavy metal translocating P-type atpase
BS21228_RS14725	COG3729	General stress protein
BS21228_RS14730	COG0662	Cupin 2, conserved barrel domain protein
BS21228_RS14735	COG2329	Antibiotic biosynthesis monooxygenase
BS21228_RS14740	COG3546	catalase activity
BS21228_RS14745	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BS21228_RS14750	COG3290	protein histidine kinase activity
BS21228_RS14755	COG4565	transcriptional regulatory protein
BS21228_RS14760	COG1301	dicarboxylic acid transport
BS21228_RS14765	COG0628	permease
BS21228_RS14770	COG1131	(ABC) transporter
BS21228_RS14775	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BS21228_RS14785	COG1960	acyl-CoA dehydrogenase activity
BS21228_RS14800	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BS21228_RS14805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS21228_RS14810	COG1181	Belongs to the D-alanine--D-alanine ligase family
BS21228_RS14815	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BS21228_RS14825	COG0513	Belongs to the DEAD box helicase family
BS21228_RS14830	COG3402	PFAM membrane-flanked domain
BS21228_RS14835	COG3428	Bacterial PH domain
BS21228_RS14840	COG0705	Rhomboid family
BS21228_RS14845	COG0736	holo-[acyl-carrier-protein] synthase activity
BS21228_RS14850	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BS21228_RS14855	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BS21228_RS14860	COG0864	Transcriptional regulator
BS21228_RS14865	COG2337	Toxic component of a toxin-antitoxin (TA) module
BS21228_RS14870	COG1366	Belongs to the anti-sigma-factor antagonist family
BS21228_RS14875	COG1366	Belongs to the anti-sigma-factor antagonist family
BS21228_RS14880	COG2172	sigma factor antagonist activity
BS21228_RS14885	COG2208	phosphoserine phosphatase activity
BS21228_RS14890	COG1366	Belongs to the anti-sigma-factor antagonist family
BS21228_RS14895	COG2172	sigma factor antagonist activity
BS21228_RS14900	COG1191	sigma factor activity
BS21228_RS14905	COG2208	phosphoserine phosphatase activity
BS21228_RS14920	COG1673	EVE domain
BS21228_RS14925	COG1846	Transcriptional regulator
BS21228_RS14930	COG2183	response to ionizing radiation
BS21228_RS14940	COG3091	SprT-like family
BS21228_RS14980	COG0582	viral genome integration into host DNA
BS21228_RS14985	COG2856	Zn peptidase
BS21228_RS14990	COG1396	sequence-specific DNA binding
BS21228_RS15015	COG1674	ftsk spoiiie
BS21228_RS15020	COG2946	Replication initiation factor
BS21228_RS15060	COG0433	COG0433 Predicted ATPase
BS21228_RS15070	COG5644	endopeptidase inhibitor activity
BS21228_RS15080	COG0791	NLP P60 protein
BS21228_RS15080	COG0741	lytic transglycosylase activity
BS21228_RS15095	COG0457	Tetratricopeptide repeat
BS21228_RS15130	COG0583	DNA-binding transcription factor activity
BS21228_RS15135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS21228_RS15145	COG5444	nuclease activity
BS21228_RS15155	COG1476	TRANSCRIPTIONal
BS21228_RS15180	COG0693	protein deglycase activity
BS21228_RS15185	COG1278	Cold shock
BS21228_RS15190	COG1329	Transcriptional regulator
BS21228_RS15200	COG0697	spore germination
BS21228_RS15205	COG2207	Transcriptional regulator
BS21228_RS15205	COG1917	Cupin 2, conserved barrel domain protein
BS21228_RS15215	COG2207	Transcriptional regulator
BS21228_RS15215	COG3708	Transcriptional regulator
BS21228_RS15220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS21228_RS15235	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
BS21228_RS15250	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS21228_RS15255	COG1309	transcriptional regulator
BS21228_RS15260	COG0697	spore germination
BS21228_RS15265	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS21228_RS15270	COG2030	dehydratase
BS21228_RS15275	COG3545	Serine hydrolase
BS21228_RS15285	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BS21228_RS15290	COG0640	Transcriptional regulator
BS21228_RS15295	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BS21228_RS15305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS21228_RS15310	COG0697	spore germination
BS21228_RS15315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS21228_RS15320	COG0076	glutamate decarboxylase activity
BS21228_RS15325	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BS21228_RS15330	COG0640	Transcriptional regulator
BS21228_RS15335	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BS21228_RS15350	COG4585	Histidine kinase
BS21228_RS15355	COG2197	response regulator
BS21228_RS15360	COG2409	Drug exporters of the RND superfamily
BS21228_RS15365	COG0596	Alpha beta hydrolase
BS21228_RS15370	COG1811	Na channel or pump
BS21228_RS15375	COG0789	Transcriptional regulator
BS21228_RS15375	COG4978	Transcriptional regulator
BS21228_RS15380	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BS21228_RS15385	COG0778	Nitroreductase
BS21228_RS15390	COG0346	lactoylglutathione lyase activity
BS21228_RS15395	COG2259	Doxx family
BS21228_RS15400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS21228_RS15425	COG2323	membrane
BS21228_RS15430	COG0071	Belongs to the small heat shock protein (HSP20) family
BS21228_RS15445	COG1309	transcriptional regulator
BS21228_RS15455	COG0456	acetyltransferase
BS21228_RS15460	COG0488	(ABC) transporter
BS21228_RS15465	COG1113	amino acid transport
BS21228_RS15470	COG2318	DinB family
BS21228_RS15475	COG1846	Transcriptional regulator
BS21228_RS15480	COG2409	Drug exporters of the RND superfamily
BS21228_RS15480	COG1033	growth of symbiont in host cell
BS21228_RS15485	COG0778	Nitroreductase
BS21228_RS15490	COG1846	Transcriptional regulator
BS21228_RS15495	COG2814	Major facilitator Superfamily
BS21228_RS15500	COG0730	response to heat
BS21228_RS15505	COG1802	Transcriptional regulator
BS21228_RS15510	COG3858	chitin binding
BS21228_RS15510	COG1388	LysM domain
BS21228_RS15515	COG1819	glycosyl
BS21228_RS15535	COG1785	Belongs to the alkaline phosphatase family
BS21228_RS15540	COG5646	InterPro IPR014922
BS21228_RS15550	COG0454	-acetyltransferase
BS21228_RS15555	COG1078	dGTPase activity
BS21228_RS15560	COG1388	LysM domain
BS21228_RS15565	COG2814	Major facilitator Superfamily
BS21228_RS15570	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BS21228_RS15585	COG2723	6-phospho-beta-galactosidase activity
BS21228_RS15590	COG2188	Transcriptional regulator
BS21228_RS15595	COG1940	carbohydrate kinase activity
BS21228_RS15605	COG4124	Belongs to the glycosyl hydrolase 26 family
BS21228_RS15650	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BS21228_RS15655	COG0802	atpase or kinase
BS21228_RS15660	COG1214	PFAM Peptidase M22, glycoprotease
BS21228_RS15665	COG0456	acetyltransferase
BS21228_RS15670	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BS21228_RS15680	COG0488	(ABC) transporter
BS21228_RS15685	COG0315	cyclic pyranopterin monophosphate synthase activity
BS21228_RS15690	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BS21228_RS15695	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BS21228_RS15700	COG0805	protein transport
BS21228_RS15715	COG1266	CAAX protease self-immunity
BS21228_RS15725	COG0459	protein refolding
BS21228_RS15740	COG0457	Tetratricopeptide repeat
BS21228_RS15745	COG1063	alcohol dehydrogenase
BS21228_RS15750	COG2211	Major facilitator Superfamily
BS21228_RS15755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BS21228_RS15765	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BS21228_RS15770	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BS21228_RS15775	COG4260	virion core protein, lumpy skin disease virus
BS21228_RS15785	COG2814	Major facilitator Superfamily
BS21228_RS15790	COG1063	alcohol dehydrogenase
BS21228_RS15795	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BS21228_RS15800	COG0823	Involved in the tonB-independent uptake of proteins
BS21228_RS15820	COG2267	carboxylic ester hydrolase activity
BS21228_RS15830	COG2132	Multicopper oxidase
BS21228_RS15835	COG1113	amino acid transport
BS21228_RS15845	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BS21228_RS15850	COG0714	Associated with various cellular activities
BS21228_RS15855	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BS21228_RS15860	COG1305	Transglutaminase-like
BS21228_RS15865	COG0519	Catalyzes the synthesis of GMP from XMP
BS21228_RS15865	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BS21228_RS15875	COG2252	PERMEase
BS21228_RS15880	COG3064	Membrane
BS21228_RS15890	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BS21228_RS15900	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BS21228_RS15905	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BS21228_RS15910	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BS21228_RS15915	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BS21228_RS15920	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BS21228_RS15925	COG0047	phosphoribosylformylglycinamidine synthase activity
BS21228_RS15930	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BS21228_RS15935	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BS21228_RS15940	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BS21228_RS15945	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BS21228_RS15950	COG0138	bifunctional purine biosynthesis protein purh
BS21228_RS15955	COG0151	Belongs to the GarS family
BS21228_RS15960	COG1522	sequence-specific DNA binding
BS21228_RS15965	COG0531	amino acid
BS21228_RS15975	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BS21228_RS15980	COG1470	cell adhesion involved in biofilm formation
BS21228_RS15985	COG4496	protein, YerC YecD
BS21228_RS15990	COG0069	glutamate synthase activity
BS21228_RS15995	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
BS21228_RS16000	COG0210	DNA helicase
BS21228_RS16005	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BS21228_RS16010	COG4851	CamS sex pheromone cAM373 precursor
BS21228_RS16020	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BS21228_RS16025	COG1285	pathogenesis
BS21228_RS16030	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BS21228_RS16035	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BS21228_RS16040	COG0154	amidase activity
BS21228_RS16045	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BS21228_RS16050	COG1309	transcriptional regulator
BS21228_RS16055	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BS21228_RS16060	COG1597	lipid kinase activity
BS21228_RS16065	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BS21228_RS16100	COG5444	nuclease activity
BS21228_RS16110	COG0457	Tetratricopeptide repeat
BS21228_RS16120	COG0217	transcriptional regulatory protein
BS21228_RS16130	COG1309	transcriptional regulator
BS21228_RS16145	COG3546	catalase activity
BS21228_RS16150	COG0454	-acetyltransferase
BS21228_RS16160	COG5578	integral membrane protein
BS21228_RS16165	COG2972	Histidine kinase
BS21228_RS16175	COG1653	transport
BS21228_RS16180	COG1175	transmembrane transport
BS21228_RS16185	COG0395	ABC-type sugar transport system, permease component
BS21228_RS16190	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BS21228_RS16195	COG2207	Transcriptional regulator
BS21228_RS16200	COG2755	lipolytic protein G-D-S-L family
BS21228_RS16210	COG5578	integral membrane protein
BS21228_RS16215	COG3401	FG-GAP repeat protein
BS21228_RS16220	COG3401	FG-GAP repeat protein
BS21228_RS16225	COG2755	lipolytic protein G-D-S-L family
BS21228_RS16240	COG1653	transport
BS21228_RS16245	COG4209	transmembrane transport
BS21228_RS16250	COG0395	ABC-type sugar transport system, permease component
BS21228_RS16255	COG1486	melibiose metabolic process
BS21228_RS16260	COG2323	membrane
BS21228_RS16265	COG2329	Antibiotic biosynthesis monooxygenase
BS21228_RS16270	COG0346	lactoylglutathione lyase activity
BS21228_RS16285	COG5583	Uncharacterized small protein (DUF2292)
BS21228_RS16290	COG0670	Belongs to the BI1 family
BS21228_RS16295	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BS21228_RS16310	COG3328	transposase activity
BS21228_RS16320	COG2124	cytochrome p450
BS21228_RS16320	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BS21228_RS16330	COG1368	sulfuric ester hydrolase activity
BS21228_RS16335	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BS21228_RS16340	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BS21228_RS16345	COG1442	glycosyl transferase family 8
BS21228_RS16350	COG1216	Glycosyl transferase, family 2
BS21228_RS16355	COG1442	glycosyl transferase family 8
BS21228_RS16360	COG2223	nitrite transmembrane transporter activity
BS21228_RS16365	COG1011	Hydrolase
BS21228_RS16370	COG0531	amino acid
BS21228_RS16375	COG1012	belongs to the aldehyde dehydrogenase family
BS21228_RS16380	COG0840	transmembrane signaling receptor activity
BS21228_RS16385	COG0488	(ABC) transporter
BS21228_RS16395	COG0789	Transcriptional regulator
BS21228_RS16400	COG2814	Major facilitator Superfamily
BS21228_RS16420	COG0488	(ABC) transporter
BS21228_RS16425	COG0513	Belongs to the DEAD box helicase family
BS21228_RS16435	COG3866	Pectate lyase
BS21228_RS16440	COG0471	metal ion transport
BS21228_RS16445	COG3290	protein histidine kinase activity
BS21228_RS16450	COG4565	transcriptional regulatory protein
BS21228_RS16455	COG3181	Tripartite tricarboxylate transporter family receptor
BS21228_RS16460	COG2851	Citrate transporter
BS21228_RS16465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BS21228_RS16470	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BS21228_RS16475	COG1254	Belongs to the acylphosphatase family
BS21228_RS16480	COG2258	MOSC domain
BS21228_RS16500	COG0024	Methionine aminopeptidase
BS21228_RS16505	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS21228_RS16505	COG1263	PTS System
BS21228_RS16510	COG1368	sulfuric ester hydrolase activity
BS21228_RS16525	COG1115	amino acid carrier protein
BS21228_RS16535	COG0697	spore germination
BS21228_RS16540	COG1263	PTS System
BS21228_RS16540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS21228_RS16545	COG0366	Alpha amylase catalytic
BS21228_RS16550	COG2188	Transcriptional regulator
BS21228_RS16555	COG0778	Nitroreductase
BS21228_RS16560	COG0737	Belongs to the 5'-nucleotidase family
BS21228_RS16565	COG0693	protein deglycase activity
BS21228_RS16575	COG2814	Major facilitator Superfamily
BS21228_RS16580	COG4840	Belongs to the UPF0435 family
BS21228_RS16585	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BS21228_RS16590	COG4980	gas vesicle protein
BS21228_RS16595	COG1295	ribonuclease BN
BS21228_RS16600	COG0477	Major facilitator Superfamily
BS21228_RS16605	COG0387	Pfam Sodium calcium exchanger
BS21228_RS16615	COG0668	transmembrane transport
BS21228_RS16620	COG0535	radical SAM domain protein
BS21228_RS16630	COG0726	polysaccharide deacetylase
BS21228_RS16635	COG2084	Dehydrogenase
BS21228_RS16640	COG0598	Magnesium transport protein CorA
BS21228_RS16645	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BS21228_RS16650	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BS21228_RS16660	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BS21228_RS16665	COG4637	Psort location Cytoplasmic, score
BS21228_RS16675	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BS21228_RS16680	COG0022	dehydrogenase e1 component
BS21228_RS16685	COG0508	dehydrogenase complex catalyzes the overall conversion of
BS21228_RS16690	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BS21228_RS16695	COG3284	Transcriptional regulator
BS21228_RS16705	COG1742	UPF0060 membrane protein
BS21228_RS16730	COG4842	Belongs to the WXG100 family
BS21228_RS16735	COG1486	melibiose metabolic process
BS21228_RS16740	COG1737	Transcriptional regulator
BS21228_RS16745	COG1263	PTS System
BS21228_RS16745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS21228_RS16750	COG5434	Belongs to the glycosyl hydrolase 28 family
BS21228_RS16755	COG1132	(ABC) transporter
BS21228_RS16760	COG1132	(ABC) transporter
BS21228_RS16765	COG2259	Doxx family
BS21228_RS16770	COG2514	catechol 2,3-dioxygenase activity
BS21228_RS16775	COG1917	Cupin 2, conserved barrel domain protein
BS21228_RS16775	COG4977	sequence-specific DNA binding
BS21228_RS16780	COG2814	Major facilitator Superfamily
BS21228_RS16785	COG1082	Xylose isomerase domain protein TIM barrel
BS21228_RS16795	COG4585	Histidine kinase
BS21228_RS16800	COG2197	response regulator
BS21228_RS16805	COG1131	(ABC) transporter
BS21228_RS16810	COG0842	Transport permease protein
BS21228_RS16810	COG1511	domain protein
BS21228_RS16815	COG0842	Transport permease protein
BS21228_RS16820	COG1695	Transcriptional regulator
BS21228_RS16825	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BS21228_RS16830	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
BS21228_RS16835	COG1309	transcriptional regulator
BS21228_RS16840	COG2814	Major facilitator Superfamily
BS21228_RS16845	COG2318	DinB family
BS21228_RS16855	COG1846	Transcriptional regulator
BS21228_RS16860	COG0392	lysyltransferase activity
BS21228_RS16860	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BS21228_RS16865	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS21228_RS16870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS21228_RS16875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS21228_RS16880	COG0384	phenazine biosynthesis protein PhzF
BS21228_RS16885	COG0778	Nitroreductase
BS21228_RS16900	COG1090	epimerase
BS21228_RS16905	COG2137	regulation of response to DNA damage stimulus
BS21228_RS16915	COG2814	Major facilitator Superfamily
BS21228_RS16930	COG3103	Sh3 type 3 domain protein
BS21228_RS16935	COG5658	integral membrane protein
BS21228_RS16940	COG0596	Alpha beta hydrolase
BS21228_RS16945	COG0463	Glycosyl transferase, family 2
BS21228_RS16950	COG4485	Bacterial membrane protein, YfhO
BS21228_RS16955	COG1988	membrane-bound metal-dependent
BS21228_RS16960	COG1194	a g-specific adenine glycosylase
BS21228_RS16970	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_RS16985	COG3557	Belongs to the UPF0374 family
BS21228_RS16990	COG1132	(ABC) transporter
BS21228_RS16995	COG4129	membrane
BS21228_RS17000	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BS21228_RS17005	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BS21228_RS17010	COG0735	belongs to the Fur family
BS21228_RS17120	COG4326	sporulation control protein
BS21228_RS17130	COG5577	PFAM Coat F domain
BS21228_RS17135	COG3340	Belongs to the peptidase S51 family
BS21228_RS17140	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BS21228_RS17155	COG0753	catalase activity
BS21228_RS17160	COG1116	anion transmembrane transporter activity
BS21228_RS17165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BS21228_RS17170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BS21228_RS17175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BS21228_RS17185	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BS21228_RS17195	COG1476	TRANSCRIPTIONal
BS21228_RS17205	COG3382	B3 4 domain protein
BS21228_RS17210	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BS21228_RS17220	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BS21228_RS17225	COG0789	Transcriptional regulator
BS21228_RS17230	COG1664	Polymer-forming cytoskeletal
BS21228_RS17235	COG1664	Polymer-forming cytoskeletal
BS21228_RS17240	COG2766	serine protein kinase
BS21228_RS17245	COG2718	Belongs to the UPF0229 family
BS21228_RS17250	COG1846	Transcriptional regulator
BS21228_RS17255	COG1566	PFAM secretion protein HlyD family protein
BS21228_RS17260	COG2814	Major facilitator Superfamily
BS21228_RS17265	COG0655	NAD(P)H dehydrogenase (quinone) activity
BS21228_RS17285	COG1725	Transcriptional regulator
BS21228_RS17290	COG1131	(ABC) transporter
BS21228_RS17295	COG1131	(ABC) transporter
BS21228_RS17300	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BS21228_RS17305	COG1278	Cold shock
BS21228_RS17315	COG1464	Belongs to the NlpA lipoprotein family
BS21228_RS17320	COG3706	GGDEF domain
BS21228_RS17325	COG1823	symporter activity
BS21228_RS17330	COG5444	nuclease activity
BS21228_RS17355	COG0582	viral genome integration into host DNA
BS21228_RS17360	COG2946	Replication initiation factor
BS21228_RS17410	COG5644	endopeptidase inhibitor activity
BS21228_RS17415	COG0741	lytic transglycosylase activity
BS21228_RS17415	COG0791	NLP P60 protein
BS21228_RS17435	COG0457	Tetratricopeptide repeat
BS21228_RS17460	COG0737	Belongs to the 5'-nucleotidase family
BS21228_RS17460	COG1525	nuclease
BS21228_RS17460	COG4085	toxin activity
BS21228_RS17465	COG3764	Sortase (surface protein transpeptidase)
BS21228_RS17470	COG0564	pseudouridine synthase activity
BS21228_RS17480	COG0517	IMP dehydrogenase activity
BS21228_RS17485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BS21228_RS17490	COG3153	acetyltransferase
BS21228_RS17490	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BS21228_RS17495	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BS21228_RS17500	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BS21228_RS17505	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BS21228_RS17510	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BS21228_RS17515	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BS21228_RS17520	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BS21228_RS17525	COG4585	Histidine kinase
BS21228_RS17525	COG2203	Gaf domain
BS21228_RS17530	COG2197	response regulator
BS21228_RS17535	COG0431	NADPH-dependent FMN reductase
BS21228_RS17550	COG0791	NLP P60 protein
BS21228_RS17550	COG1388	LysM domain
BS21228_RS17555	COG1959	2 iron, 2 sulfur cluster binding
BS21228_RS17560	COG0668	transmembrane transport
BS21228_RS17565	COG2719	SpoVR family
BS21228_RS17570	COG1785	Belongs to the alkaline phosphatase family
BS21228_RS17575	COG0791	NLP P60 protein
BS21228_RS17575	COG1388	LysM domain
BS21228_RS17580	COG0583	DNA-binding transcription factor activity
BS21228_RS17585	COG0372	Belongs to the citrate synthase family
BS21228_RS17590	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_RS17595	COG0531	amino acid
BS21228_RS17600	COG0733	neurotransmitter:sodium symporter activity
BS21228_RS17605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS21228_RS17610	COG0456	acetyltransferase
BS21228_RS17625	COG1595	DNA-templated transcription, initiation
BS21228_RS17630	COG0667	Aldo Keto reductase
BS21228_RS17635	COG0204	Acyl-transferase
BS21228_RS17640	COG1253	flavin adenine dinucleotide binding
BS21228_RS17645	COG0789	Transcriptional regulator
BS21228_RS17655	COG1253	flavin adenine dinucleotide binding
BS21228_RS17660	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BS21228_RS17665	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BS21228_RS17670	COG0584	glycerophosphoryl diester phosphodiesterase
BS21228_RS17680	COG0668	transmembrane transport
BS21228_RS17685	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BS21228_RS17690	COG0726	polysaccharide deacetylase
BS21228_RS17695	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BS21228_RS17700	COG1757	Na H antiporter
BS21228_RS17705	COG0589	response to stress
BS21228_RS17715	COG1132	(ABC) transporter
BS21228_RS17720	COG1132	(ABC) transporter
BS21228_RS17725	COG0702	epimerase
BS21228_RS17750	COG0189	ligase activity
BS21228_RS17755	COG0189	ligase activity
BS21228_RS17760	COG4399	Belongs to the UPF0754 family
BS21228_RS17765	COG3679	Belongs to the UPF0342 family
BS21228_RS17775	COG0561	phosphatase activity
BS21228_RS17780	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BS21228_RS17785	COG0475	glutathione-regulated potassium exporter activity
BS21228_RS17790	COG0490	domain, Protein
BS21228_RS17800	COG1024	Enoyl-CoA hydratase
BS21228_RS17810	COG4152	abc transporter atp-binding protein
BS21228_RS17815	COG1668	transmembrane transport
BS21228_RS17820	COG0420	3'-5' exonuclease activity
BS21228_RS17825	COG4717	serine-type aminopeptidase activity
BS21228_RS17830	COG3481	metal-dependent phosphohydrolase, HD sub domain
BS21228_RS17840	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BS21228_RS17870	COG1846	Transcriptional regulator
BS21228_RS17875	COG4980	gas vesicle protein
BS21228_RS17890	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BS21228_RS17895	COG0537	adenosine 5'-monophosphoramidase activity
BS21228_RS17900	COG1131	(ABC) transporter
BS21228_RS17905	COG4473	ABC transporter
BS21228_RS17915	COG1473	amidohydrolase
BS21228_RS17920	COG3069	C4-dicarboxylate transmembrane transporter activity
BS21228_RS17930	COG2329	Antibiotic biosynthesis monooxygenase
BS21228_RS17935	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BS21228_RS17940	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BS21228_RS17945	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BS21228_RS17950	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BS21228_RS17955	COG1309	transcriptional regulator
BS21228_RS17960	COG1511	domain protein
BS21228_RS17965	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BS21228_RS17970	COG4377	Putative membrane peptidase family (DUF2324)
BS21228_RS17980	COG1363	Peptidase, m42
BS21228_RS17985	COG4405	Protein conserved in bacteria
BS21228_RS17990	COG1301	dicarboxylic acid transport
BS21228_RS18000	COG1234	tRNA 3'-trailer cleavage
BS21228_RS18005	COG0095	Lipoate-protein ligase
BS21228_RS18010	COG0702	epimerase
BS21228_RS18015	COG0318	PFAM AMP-dependent synthetase and ligase
BS21228_RS18025	COG0501	Belongs to the peptidase M48B family
BS21228_RS18035	COG0456	acetyltransferase
BS21228_RS18040	COG0604	alcohol dehydrogenase
BS21228_RS18045	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BS21228_RS18050	COG0406	alpha-ribazole phosphatase activity
BS21228_RS18055	COG0183	Belongs to the thiolase family
BS21228_RS18060	COG0318	PFAM AMP-dependent synthetase and ligase
BS21228_RS18065	COG1268	BioY protein
BS21228_RS18070	COG0840	transmembrane signaling receptor activity
BS21228_RS18080	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_RS18090	COG4903	ComK protein
BS21228_RS18095	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_RS18105	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BS21228_RS18120	COG0398	Pfam SNARE associated Golgi protein
BS21228_RS18125	COG0681	Belongs to the peptidase S26 family
BS21228_RS18130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BS21228_RS18135	COG1846	Transcriptional regulator
BS21228_RS18150	COG0738	Major facilitator superfamily
BS21228_RS18155	COG0673	inositol 2-dehydrogenase activity
BS21228_RS18160	COG0561	phosphatase activity
BS21228_RS18165	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BS21228_RS18170	COG1609	Transcriptional regulator
BS21228_RS18175	COG3180	Ammonia monooxygenase
BS21228_RS18180	COG2814	Major facilitator Superfamily
BS21228_RS18180	COG0477	Major facilitator Superfamily
BS21228_RS18185	COG4533	DNA binding
BS21228_RS18205	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BS21228_RS18210	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BS21228_RS18215	COG1074	ATP-dependent DNA helicase activity
BS21228_RS18220	COG0420	3'-5' exonuclease activity
BS21228_RS18230	COG1403	HNH endonuclease
BS21228_RS18270	COG5337	Spore coat protein CotH
BS21228_RS18275	COG0179	Fumarylacetoacetate (FAA) hydrolase
BS21228_RS18285	COG1404	Belongs to the peptidase S8 family
BS21228_RS18295	COG0367	asparagine synthase
BS21228_RS18300	COG1562	ergosterol biosynthetic process
BS21228_RS18305	COG0534	Mate efflux family protein
BS21228_RS18310	COG2207	Transcriptional regulator
BS21228_RS18310	COG1917	Cupin 2, conserved barrel domain protein
BS21228_RS18315	COG1609	Transcriptional regulator
BS21228_RS18320	COG0673	inositol 2-dehydrogenase activity
BS21228_RS18325	COG2318	DinB family
BS21228_RS18330	COG1279	arginine transmembrane transporter activity
BS21228_RS18335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS21228_RS18340	COG1357	PFAM Pentapeptide repeats (8 copies)
BS21228_RS18345	COG2267	carboxylic ester hydrolase activity
BS21228_RS18355	COG2153	protein acetylation
BS21228_RS18360	COG0646	methionine synthase
BS21228_RS18360	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BS21228_RS18365	COG1666	GTP binding
BS21228_RS18370	COG2996	Protein conserved in bacteria
BS21228_RS18380	COG1307	EDD domain protein, DegV family
BS21228_RS18385	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BS21228_RS18400	COG0561	phosphatase activity
BS21228_RS18405	COG1073	alpha beta
BS21228_RS18410	COG2151	metal-sulfur cluster biosynthetic enzyme
BS21228_RS18430	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BS21228_RS18435	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BS21228_RS18445	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BS21228_RS18450	COG0505	Belongs to the CarA family
BS21228_RS18455	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BS21228_RS18460	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BS21228_RS18480	COG2267	carboxylic ester hydrolase activity
BS21228_RS18490	COG1744	ABC transporter substrate-binding protein PnrA-like
BS21228_RS18505	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BS21228_RS18510	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BS21228_RS18515	COG5504	Zn-dependent protease
BS21228_RS18520	COG0444	Belongs to the ABC transporter superfamily
BS21228_RS18525	COG4608	Belongs to the ABC transporter superfamily
BS21228_RS18535	COG0601	transmembrane transport
BS21228_RS18540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BS21228_RS18550	COG0180	Tryptophanyl-tRNA synthetase
BS21228_RS18555	COG4166	transmembrane transport
BS21228_RS18560	COG0601	transmembrane transport
BS21228_RS18565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BS21228_RS18570	COG0444	Belongs to the ABC transporter superfamily
BS21228_RS18575	COG4608	Belongs to the ABC transporter superfamily
BS21228_RS18580	COG2814	Major facilitator Superfamily
BS21228_RS18585	COG0456	acetyltransferase
BS21228_RS18590	COG1393	Belongs to the ArsC family
BS21228_RS18595	COG0861	Integral membrane protein TerC family
BS21228_RS18600	COG4862	establishment of competence for transformation
BS21228_RS18605	COG4469	Competence protein
BS21228_RS18610	COG1164	Oligoendopeptidase f
BS21228_RS18625	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BS21228_RS18630	COG2346	COG2346, Truncated hemoglobins
BS21228_RS18635	COG0741	lytic transglycosylase activity
BS21228_RS18640	COG4116	CYTH
BS21228_RS18650	COG2357	RelA SpoT domain protein
BS21228_RS18655	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BS21228_RS18660	COG0564	pseudouridine synthase activity
BS21228_RS18665	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BS21228_RS18670	COG0569	domain protein
BS21228_RS18670	COG0475	glutathione-regulated potassium exporter activity
BS21228_RS18675	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BS21228_RS18680	COG0352	thiamine-phosphate diphosphorylase activity
BS21228_RS18685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BS21228_RS18690	COG2104	thiamine diphosphate biosynthetic process
BS21228_RS18695	COG2022	thiamine diphosphate biosynthetic process
BS21228_RS18700	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BS21228_RS18705	COG0351	phosphomethylpyrimidine kinase
BS21228_RS18710	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BS21228_RS18765	COG0210	DNA helicase
BS21228_RS18775	COG2153	protein acetylation
BS21228_RS18780	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BS21228_RS18785	COG2382	esterase
BS21228_RS18790	COG0626	cystathionine gamma-synthase activity
BS21228_RS18795	COG0626	cystathionine gamma-synthase activity
BS21228_RS18800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS21228_RS18805	COG5505	Protein of unknown function (DUF819)
BS21228_RS18840	COG1396	sequence-specific DNA binding
BS21228_RS18905	COG0457	Tetratricopeptide repeat
BS21228_RS18910	COG5444	nuclease activity
BS21228_RS18925	COG3328	transposase activity
BS21228_RS18985	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BS21228_RS18995	COG3711	transcriptional antiterminator
BS21228_RS18995	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS21228_RS19000	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS21228_RS19000	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BS21228_RS19000	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BS21228_RS19005	COG1482	cell wall glycoprotein biosynthetic process
BS21228_RS19020	COG3328	transposase activity
BS21228_RS19025	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS21228_RS19035	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BS21228_RS19055	COG0109	protoheme IX farnesyltransferase activity
BS21228_RS19065	COG0726	polysaccharide deacetylase
BS21228_RS19080	COG5504	Zn-dependent protease
BS21228_RS19085	COG2205	protein histidine kinase activity
BS21228_RS19100	COG2427	Protein of unknown function (DUF1641)
BS21228_RS19110	COG1051	belongs to the nudix hydrolase family
BS21228_RS19120	COG2124	cytochrome p450
BS21228_RS19125	COG1819	glycosyl
BS21228_RS19135	COG1587	Uroporphyrinogen-III synthase
BS21228_RS19140	COG0390	transport system, permease component
BS21228_RS19145	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BS21228_RS19150	COG0697	spore germination
BS21228_RS19165	COG1252	NADH dehydrogenase
BS21228_RS19170	COG1904	glucuronate isomerase
BS21228_RS19175	COG2211	Major facilitator Superfamily
BS21228_RS19180	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BS21228_RS19185	COG1063	alcohol dehydrogenase
BS21228_RS19190	COG1312	Catalyzes the dehydration of D-mannonate
BS21228_RS19195	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_RS19200	COG2271	Major facilitator Superfamily
BS21228_RS19205	COG1609	Transcriptional regulator
BS21228_RS19210	COG0246	Mannitol dehydrogenase
BS21228_RS19215	COG2721	sulfolactate sulfo-lyase activity
BS21228_RS19220	COG0730	response to heat
BS21228_RS19225	COG2318	DinB family
BS21228_RS19245	COG0457	Tetratricopeptide repeat
BS21228_RS19260	COG1388	LysM domain
BS21228_RS19260	COG3409	Peptidoglycan-binding domain 1 protein
BS21228_RS19260	COG5632	N-Acetylmuramoyl-L-alanine amidase
BS21228_RS19270	COG4195	phage-related replication protein
BS21228_RS19275	COG3546	catalase activity
BS21228_RS19280	COG2856	Zn peptidase
BS21228_RS19285	COG1396	sequence-specific DNA binding
BS21228_RS19295	COG1522	sequence-specific DNA binding
BS21228_RS19300	COG1484	DNA-dependent DNA replication
BS21228_RS19320	COG1595	DNA-templated transcription, initiation
BS21228_RS19325	COG5484	DNA packaging
BS21228_RS19325	COG3728	DNA packaging
BS21228_RS19330	COG1783	phage Terminase large subunit
BS21228_RS19335	COG5518	Phage portal protein
BS21228_RS19340	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BS21228_RS19345	COG4653	Phage capsid family
BS21228_RS19395	COG5412	phage tail tape measure protein
BS21228_RS19395	COG3953	SLT domain
BS21228_RS19395	COG5412	phage tail tape measure protein
BS21228_RS19395	COG3953	SLT domain
BS21228_RS19395	COG5412	phage tail tape measure protein
BS21228_RS19395	COG3953	SLT domain
BS21228_RS19400	COG1652	LysM domain
BS21228_RS19405	COG4193	domain, Protein
BS21228_RS19415	COG3628	GPW Gp25 family protein
BS21228_RS19420	COG3299	homolog of phage Mu protein gp47
BS21228_RS19425	COG3778	Protein conserved in bacteria
BS21228_RS19465	COG3409	Peptidoglycan-binding domain 1 protein
BS21228_RS19465	COG5632	N-Acetylmuramoyl-L-alanine amidase
BS21228_RS19480	COG0306	phosphate transporter
BS21228_RS19485	COG1392	Phosphate transport regulator
BS21228_RS19490	COG0531	amino acid
BS21228_RS19495	COG0346	lactoylglutathione lyase activity
BS21228_RS19500	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BS21228_RS19505	COG0463	Glycosyl transferase, family 2
BS21228_RS19510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BS21228_RS19515	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BS21228_RS19520	COG2362	D-Aminopeptidase
BS21228_RS19525	COG0601	transmembrane transport
BS21228_RS19530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BS21228_RS19535	COG0444	Belongs to the ABC transporter superfamily
BS21228_RS19540	COG4166	transmembrane transport
BS21228_RS19545	COG1619	proteins homologs of microcin C7 resistance protein MccF
BS21228_RS19550	COG4948	Mandelate Racemase Muconate Lactonizing
BS21228_RS19555	COG0791	NLP P60 protein
BS21228_RS19560	COG4608	Belongs to the ABC transporter superfamily
BS21228_RS19565	COG2706	6-phosphogluconolactonase activity
BS21228_RS19575	COG1607	acyl-coa hydrolase
BS21228_RS19580	COG1017	nitric oxide dioxygenase activity
BS21228_RS19580	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BS21228_RS19590	COG2323	membrane
BS21228_RS19595	COG2318	DinB family
BS21228_RS19600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS21228_RS19605	COG2076	Multidrug Resistance protein
BS21228_RS19610	COG2076	Multidrug Resistance protein
BS21228_RS19615	COG0788	formyltetrahydrofolate deformylase activity
BS21228_RS19620	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BS21228_RS19625	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BS21228_RS19630	COG1764	response to oxidative stress
BS21228_RS19635	COG1846	Transcriptional regulator
BS21228_RS19640	COG1764	response to oxidative stress
BS21228_RS19650	COG0590	tRNA wobble adenosine to inosine editing
BS21228_RS19655	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BS21228_RS19660	COG1404	Belongs to the peptidase S8 family
BS21228_RS19665	COG1366	Belongs to the anti-sigma-factor antagonist family
BS21228_RS19670	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BS21228_RS19675	COG1122	ATPase activity
BS21228_RS19680	COG4721	ABC-type cobalt transport system, permease component
BS21228_RS19690	COG0745	RESPONSE REGULATOR receiver
BS21228_RS19695	COG5002	protein histidine kinase activity
BS21228_RS19695	COG3850	Histidine kinase
BS21228_RS19700	COG3212	peptidase
BS21228_RS19705	COG3212	peptidase
BS21228_RS19720	COG2239	Acts as a magnesium transporter
BS21228_RS19725	COG0789	Transcriptional regulator
BS21228_RS19740	COG1846	Transcriptional regulator
BS21228_RS19745	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BS21228_RS19750	COG0726	polysaccharide deacetylase
BS21228_RS19755	COG1408	metallophosphoesterase
BS21228_RS19765	COG0463	Glycosyl transferase, family 2
BS21228_RS19770	COG1793	dna ligase
BS21228_RS19770	COG3285	dna ligase
BS21228_RS19775	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BS21228_RS19780	COG5001	Diguanylate cyclase
BS21228_RS19780	COG3300	MHYT domain
BS21228_RS19785	COG0586	Pfam SNARE associated Golgi protein
BS21228_RS19790	COG0861	Integral membrane protein TerC family
BS21228_RS19795	COG1191	sigma factor activity
BS21228_RS19815	COG0501	Belongs to the peptidase M48B family
BS21228_RS19820	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BS21228_RS19840	COG3594	Acyltransferase
BS21228_RS19845	COG5002	protein histidine kinase activity
BS21228_RS19850	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BS21228_RS19855	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BS21228_RS19860	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BS21228_RS19865	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BS21228_RS19870	COG0436	Aminotransferase
BS21228_RS19875	COG1850	ribulose-bisphosphate carboxylase activity
BS21228_RS19880	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
BS21228_RS19885	COG0235	Class ii aldolase
BS21228_RS19890	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BS21228_RS19895	COG3339	Conserved Protein
BS21228_RS19910	COG3852	Histidine kinase
BS21228_RS19915	COG1846	Transcriptional regulator
BS21228_RS19920	COG1360	Flagellar Motor Protein
BS21228_RS19925	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BS21228_RS19930	COG0542	response to heat
BS21228_RS19935	COG3949	Membrane
BS21228_RS19940	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BS21228_RS19945	COG0720	synthase
BS21228_RS19950	COG0602	queuosine metabolic process
BS21228_RS19955	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BS21228_RS19965	COG4873	Protein conserved in bacteria
BS21228_RS19975	COG3773	Cell wall hydrolase
BS21228_RS19980	COG2244	polysaccharide biosynthetic process
BS21228_RS19985	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS21228_RS19990	COG2217	Heavy metal translocating P-type atpase
BS21228_RS20000	COG0006	proline dipeptidase activity
BS21228_RS20005	COG1609	Transcriptional regulator
BS21228_RS20010	COG3711	transcriptional antiterminator
BS21228_RS20015	COG1263	PTS System
BS21228_RS20015	COG2190	(PTS) system
BS21228_RS20015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS21228_RS20020	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS21228_RS20025	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BS21228_RS20035	COG1533	DNA photolyase activity
BS21228_RS20040	COG0456	acetyltransferase
BS21228_RS20045	COG0840	transmembrane signaling receptor activity
BS21228_RS20050	COG2084	Dehydrogenase
BS21228_RS20055	COG3328	transposase activity
BS21228_RS20065	COG2340	Cysteine-rich secretory protein family
BS21228_RS20070	COG0768	penicillin binding
BS21228_RS20075	COG4191	Histidine kinase
BS21228_RS20080	COG0436	Aminotransferase
BS21228_RS20090	COG0784	Response regulator, receiver
BS21228_RS20090	COG0835	chemotaxis
BS21228_RS20100	COG2814	Major facilitator Superfamily
BS21228_RS20105	COG1376	ErfK ybiS ycfS ynhG family protein
BS21228_RS20110	COG1408	metallophosphoesterase
BS21228_RS20115	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_RS20120	COG2200	EAL domain
BS21228_RS20125	COG4703	Protein of unknown function (DUF1797)
BS21228_RS20130	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BS21228_RS20140	COG0517	IMP dehydrogenase activity
BS21228_RS20145	COG0583	DNA-binding transcription factor activity
BS21228_RS20150	COG0716	FMN binding
BS21228_RS20160	COG0716	FMN binding
BS21228_RS20165	COG2171	N-acyltransferase activity
BS21228_RS20170	COG1473	amidohydrolase
BS21228_RS20180	COG0668	transmembrane transport
BS21228_RS20185	COG0450	alkyl hydroperoxide reductase
BS21228_RS20190	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS21228_RS20210	COG0746	molybdenum cofactor guanylyltransferase activity
BS21228_RS20215	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BS21228_RS20220	COG0303	'Molybdopterin
BS21228_RS20225	COG1763	Mo-molybdopterin cofactor biosynthetic process
BS21228_RS20230	COG0314	molybdopterin synthase activity
BS21228_RS20235	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BS21228_RS20245	COG1132	(ABC) transporter
BS21228_RS20255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BS21228_RS20260	COG1136	(ABC) transporter
BS21228_RS20265	COG0577	efflux transmembrane transporter activity
BS21228_RS20270	COG1349	DNA-binding transcription factor activity
BS21228_RS20275	COG1105	Belongs to the carbohydrate kinase PfkB family
BS21228_RS20280	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BS21228_RS20280	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BS21228_RS20280	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS21228_RS20285	COG0681	Belongs to the peptidase S26 family
BS21228_RS20295	COG0488	(ABC) transporter
BS21228_RS20300	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BS21228_RS20305	COG2309	aminopeptidase activity
BS21228_RS20315	COG1077	Cell shape determining protein MreB Mrl
BS21228_RS20320	COG2002	toxin-antitoxin pair type II binding
BS21228_RS20325	COG3852	Histidine kinase
BS21228_RS20330	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BS21228_RS20330	COG2105	PFAM AIG2 family protein
BS21228_RS20335	COG0569	domain protein
BS21228_RS20340	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BS21228_RS20345	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BS21228_RS20350	COG5503	Protein of unknown function (DUF1447)
BS21228_RS20355	COG0561	phosphatase activity
BS21228_RS20360	COG0242	peptide deformylase activity
BS21228_RS20375	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BS21228_RS20380	COG0022	dehydrogenase e1 component
BS21228_RS20385	COG0508	dehydrogenase complex catalyzes the overall conversion of
BS21228_RS20390	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BS21228_RS20395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS21228_RS20405	COG1982	Orn Lys Arg decarboxylase major
BS21228_RS20410	COG4476	Belongs to the UPF0223 family
BS21228_RS20415	COG4493	Belongs to the UPF0637 family
BS21228_RS20425	COG0483	inositol monophosphate 1-phosphatase activity
BS21228_RS20440	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BS21228_RS20485	COG1217	gtp-binding protein TYPA
BS21228_RS20495	COG4896	Protein conserved in bacteria
BS21228_RS20505	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BS21228_RS20510	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BS21228_RS20515	COG2066	Belongs to the glutaminase family
BS21228_RS20520	COG4838	Belongs to the UPF0358 family
BS21228_RS20525	COG0772	Belongs to the SEDS family
BS21228_RS20530	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BS21228_RS20535	COG1612	heme a metabolic process
BS21228_RS20540	COG0109	protoheme IX farnesyltransferase activity
BS21228_RS20545	COG2010	Cytochrome c
BS21228_RS20545	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BS21228_RS20550	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BS21228_RS20555	COG1845	cytochrome c oxidase, subunit III
BS21228_RS20560	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BS21228_RS20565	COG3336	cytochrome c oxidase
BS21228_RS20575	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BS21228_RS20580	COG2340	Cysteine-rich secretory protein family
BS21228_RS20595	COG3679	Belongs to the UPF0342 family
BS21228_RS20600	COG4471	UPF0298 protein
BS21228_RS20605	COG0742	ribosomal rna small subunit methyltransferase
BS21228_RS20610	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BS21228_RS20615	COG3314	Sporulation integral membrane protein YlbJ
BS21228_RS20620	COG1752	Esterase of the alpha-beta hydrolase superfamily
BS21228_RS20625	COG3480	Lon protease (S16) C-terminal proteolytic domain
BS21228_RS20630	COG1323	Belongs to the UPF0348 family
BS21228_RS20640	COG1399	metal-binding, possibly nucleic acid-binding protein
BS21228_RS20655	COG0454	-acetyltransferase
BS21228_RS20660	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BS21228_RS20665	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BS21228_RS20670	COG2001	Belongs to the MraZ family
BS21228_RS20675	COG0275	rRNA processing
BS21228_RS20680	COG4839	cell division protein FtsL
BS21228_RS20685	COG0768	penicillin binding
BS21228_RS20690	COG0768	penicillin binding
BS21228_RS20695	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BS21228_RS20700	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BS21228_RS20705	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BS21228_RS20710	COG0772	Belongs to the SEDS family
BS21228_RS20715	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BS21228_RS20720	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BS21228_RS20725	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BS21228_RS20730	COG3879	Bacterial protein of unknown function (DUF881)
BS21228_RS20735	COG3879	Bacterial protein of unknown function (DUF881)
BS21228_RS20740	COG3856	small basic protein
BS21228_RS20745	COG0849	cell division
BS21228_RS20750	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BS21228_RS20755	COG1404	Belongs to the peptidase S8 family
BS21228_RS20755	COG4412	M6 family metalloprotease domain protein
BS21228_RS20765	COG1191	sigma factor activity
BS21228_RS20770	COG1191	sigma factor activity
BS21228_RS20775	COG1119	ATPase activity
BS21228_RS20780	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BS21228_RS20785	COG1873	PFAM PRC-barrel domain
BS21228_RS20790	COG1496	oxidoreductase activity
BS21228_RS20795	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BS21228_RS20800	COG1799	cell septum assembly
BS21228_RS20805	COG0762	integral membrane protein
BS21228_RS20810	COG2302	S4 RNA-binding domain
BS21228_RS20815	COG3599	regulation of cell shape
BS21228_RS20820	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BS21228_RS20825	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BS21228_RS20830	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BS21228_RS20835	COG0564	pseudouridine synthase activity
BS21228_RS20840	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BS21228_RS20845	COG2233	PERMEase
BS21228_RS20850	COG0540	Belongs to the ATCase OTCase family
BS21228_RS20855	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BS21228_RS20860	COG0505	Belongs to the CarA family
BS21228_RS20865	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BS21228_RS20870	COG0543	2 iron, 2 sulfur cluster binding
BS21228_RS20875	COG0167	dihydroorotate dehydrogenase activity
BS21228_RS20880	COG0284	orotidine-5'-phosphate decarboxylase activity
BS21228_RS20885	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BS21228_RS20890	COG0175	sulfate reduction
BS21228_RS20895	COG0306	phosphate transporter
BS21228_RS20900	COG2046	Belongs to the sulfate adenylyltransferase family
BS21228_RS20905	COG0529	Catalyzes the synthesis of activated sulfate
BS21228_RS20910	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BS21228_RS20915	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
BS21228_RS20920	COG1648	precorrin-2 dehydrogenase activity
BS21228_RS20930	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BS21228_RS20935	COG1561	YicC-like family, N-terminal region
BS21228_RS20945	COG0194	GDP metabolic process
BS21228_RS20950	COG1758	RNA polymerase activity
BS21228_RS20955	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BS21228_RS20960	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BS21228_RS20965	COG0242	peptide deformylase activity
BS21228_RS20970	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BS21228_RS20975	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BS21228_RS20975	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BS21228_RS20985	COG0631	protein serine/threonine phosphatase activity
BS21228_RS20990	COG2815	serine threonine protein kinase
BS21228_RS20990	COG0515	serine threonine protein kinase
BS21228_RS20995	COG1162	GTPase activity
BS21228_RS21000	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BS21228_RS21005	COG1564	THIamine pyrophosphokinase
BS21228_RS21015	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BS21228_RS21020	COG1302	Protein conserved in bacteria
BS21228_RS21025	COG1461	Dihydroxyacetone kinase
BS21228_RS21030	COG1760	l-serine dehydratase
BS21228_RS21035	COG1760	l-serine dehydratase
BS21228_RS21040	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BS21228_RS21045	COG1349	DNA-binding transcription factor activity
BS21228_RS21045	COG2050	protein possibly involved in aromatic compounds catabolism
BS21228_RS21050	COG0416	fatty acid biosynthetic process
BS21228_RS21055	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BS21228_RS21060	COG1028	Short-chain dehydrogenase reductase Sdr
BS21228_RS21070	COG0571	ribonuclease III activity
BS21228_RS21075	COG1196	nuclear chromosome segregation
BS21228_RS21080	COG0552	protein localization to endoplasmic reticulum
BS21228_RS21090	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BS21228_RS21095	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BS21228_RS21100	COG0228	four-way junction DNA binding
BS21228_RS21105	COG1837	Belongs to the UPF0109 family
BS21228_RS21115	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BS21228_RS21120	COG0336	Belongs to the RNA methyltransferase TrmD family
BS21228_RS21125	COG0335	large ribosomal subunit rRNA binding
BS21228_RS21130	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BS21228_RS21135	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BS21228_RS21145	COG2257	FlhB HrpN YscU SpaS Family
BS21228_RS21150	COG0045	succinate-CoA ligase (ADP-forming) activity
BS21228_RS21155	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BS21228_RS21160	COG0758	DNA mediated transformation
BS21228_RS21165	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BS21228_RS21170	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BS21228_RS21175	COG4974	Belongs to the 'phage' integrase family
BS21228_RS21180	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BS21228_RS21185	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BS21228_RS21190	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BS21228_RS21195	COG1815	bacterial-type flagellum-dependent cell motility
BS21228_RS21200	COG1558	bacterial-type flagellum-dependent cell motility
BS21228_RS21205	COG1677	Flagellar hook-basal body complex protein FliE
BS21228_RS21215	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BS21228_RS21220	COG1317	bacterial-type flagellum organization
BS21228_RS21240	COG2882	bacterial-type flagellum organization
BS21228_RS21245	COG3334	PFAM MgtE intracellular
BS21228_RS21250	COG3144	bacterial-type flagellum assembly
BS21228_RS21255	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BS21228_RS21260	COG4786	Flagellar basal body rod
BS21228_RS21265	COG1582	Flagellar protein (FlbD)
BS21228_RS21270	COG1580	Controls the rotational direction of flagella during chemotaxis
BS21228_RS21275	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BS21228_RS21280	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BS21228_RS21280	COG1776	CheC inhibitor of MCP methylation
BS21228_RS21285	COG2201	protein-glutamate methylesterase activity
BS21228_RS21290	COG3190	flagellar
BS21228_RS21295	COG1338	Plays a role in the flagellum-specific transport system
BS21228_RS21300	COG1987	bacterial-type flagellum assembly
BS21228_RS21305	COG1684	flagellar biosynthetic protein fliR
BS21228_RS21310	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BS21228_RS21315	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BS21228_RS21320	COG1419	protein localization to endoplasmic reticulum
BS21228_RS21325	COG0455	bacterial-type flagellum organization
BS21228_RS21330	COG2201	protein-glutamate methylesterase activity
BS21228_RS21335	COG0643	Histidine kinase
BS21228_RS21335	COG2198	Histidine kinase
BS21228_RS21340	COG0835	chemotaxis
BS21228_RS21350	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BS21228_RS21355	COG1191	sigma factor activity
BS21228_RS21365	COG0052	Belongs to the universal ribosomal protein uS2 family
BS21228_RS21370	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BS21228_RS21375	COG0528	UMP kinase activity
BS21228_RS21380	COG0233	cytoplasmic translational termination
BS21228_RS21385	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BS21228_RS21390	COG4589	Belongs to the CDS family
BS21228_RS21395	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BS21228_RS21400	COG0750	zinc metalloprotease
BS21228_RS21405	COG0442	prolyl-tRNA aminoacylation
BS21228_RS21410	COG2176	DNA-directed DNA polymerase activity
BS21228_RS21415	COG0779	Required for maturation of 30S ribosomal subunits
BS21228_RS21420	COG0195	Participates in both transcription termination and antitermination
BS21228_RS21425	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BS21228_RS21430	COG1358	cellular component organization or biogenesis
BS21228_RS21435	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BS21228_RS21440	COG1550	Protein conserved in bacteria
BS21228_RS21445	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BS21228_RS21450	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BS21228_RS21455	COG0196	riboflavin kinase activity
BS21228_RS21460	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BS21228_RS21465	COG1185	polyribonucleotide nucleotidyltransferase activity
BS21228_RS21470	COG0726	polysaccharide deacetylase
BS21228_RS21475	COG0612	Peptidase, M16
BS21228_RS21480	COG1873	PFAM PRC-barrel domain
BS21228_RS21485	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BS21228_RS21490	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BS21228_RS21495	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BS21228_RS21500	COG0527	aspartate kinase activity
BS21228_RS21505	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BS21228_RS21510	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BS21228_RS21515	COG0740	serine-type endopeptidase activity
BS21228_RS21525	COG1674	ftsk spoiiie
BS21228_RS21525	COG4980	gas vesicle protein
BS21228_RS21530	COG2188	Transcriptional regulator
BS21228_RS21535	COG2814	Major facilitator Superfamily
BS21228_RS21540	COG0612	Peptidase, M16
BS21228_RS21545	COG0612	Peptidase, M16
BS21228_RS21550	COG0300	oxidoreductase activity
BS21228_RS21565	COG1426	Protein conserved in bacteria
BS21228_RS21570	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BS21228_RS21575	COG1546	Belongs to the CinA family
BS21228_RS21575	COG1058	Belongs to the CinA family
BS21228_RS21580	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BS21228_RS21585	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BS21228_RS21590	COG1418	mRNA catabolic process
BS21228_RS21595	COG1692	metallophosphoesterase
BS21228_RS21600	COG2359	stage V sporulation protein S
BS21228_RS21605	COG1063	alcohol dehydrogenase
BS21228_RS21610	COG0156	8-amino-7-oxononanoate synthase activity
BS21228_RS21615	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BS21228_RS21620	COG4550	Control of competence regulator ComK, YlbF/YmcA
BS21228_RS21630	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BS21228_RS21635	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BS21228_RS21710	COG3328	transposase activity
BS21228_RS21730	COG3226	Transcriptional regulator
BS21228_RS21740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BS21228_RS21745	COG1404	Belongs to the peptidase S8 family
BS21228_RS21755	COG4195	phage-related replication protein
BS21228_RS21760	COG1764	response to oxidative stress
BS21228_RS21765	COG2076	Multidrug Resistance protein
BS21228_RS21770	COG2076	Multidrug Resistance protein
BS21228_RS21785	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BS21228_RS21790	COG1923	regulation of RNA biosynthetic process
BS21228_RS21805	COG1780	Probably involved in ribonucleotide reductase function
BS21228_RS21810	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BS21228_RS21815	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BS21228_RS21820	COG4112	unkown
BS21228_RS21825	COG0860	N-Acetylmuramoyl-L-alanine amidase
BS21228_RS21835	COG0464	growth
BS21228_RS21840	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BS21228_RS21845	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BS21228_RS21850	COG0789	Transcriptional regulator
BS21228_RS21855	COG0174	glutamine synthetase
BS21228_RS21860	COG4974	Belongs to the 'phage' integrase family
BS21228_RS21880	COG3645	SOS response
BS21228_RS21880	COG3646	Phage regulatory protein
BS21228_RS22025	COG3953	SLT domain
BS21228_RS22025	COG5412	phage tail tape measure protein
BS21228_RS22070	COG5632	N-Acetylmuramoyl-L-alanine amidase
BS21228_RS22070	COG1388	LysM domain
BS21228_RS22070	COG3409	Peptidoglycan-binding domain 1 protein
BS21228_RS22080	COG5444	nuclease activity
BS21228_RS22120	COG1525	nuclease
BS21228_RS22225	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BS21228_RS22275	COG0457	Tetratricopeptide repeat
BS21228_RS22410	COG0791	NLP P60 protein
BS21228_RS22410	COG3883	PFAM NLP P60 protein
BS21228_RS22465	COG0629	single-stranded DNA binding
BS21228_RS22480	COG0582	viral genome integration into host DNA
BS21228_RS22510	COG1793	dna ligase
BS21228_RS22525	COG1525	nuclease