locus-tag	class	description
B7470_RS00035	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7470_RS00040	COG2027	D-alanyl-D-alanine carboxypeptidase
B7470_RS00045	COG2017	converts alpha-aldose to the beta-anomer
B7470_RS00050	COG0534	Mate efflux family protein
B7470_RS00070	COG0582	viral genome integration into host DNA
B7470_RS00075	COG0166	Belongs to the GPI family
B7470_RS00080	COG0405	Gamma-glutamyltransferase
B7470_RS00085	COG0583	DNA-binding transcription factor activity
B7470_RS00090	COG0604	alcohol dehydrogenase
B7470_RS00095	COG0493	'glutamate synthase
B7470_RS00100	COG0067	glutamate synthase
B7470_RS00100	COG0070	glutamate synthase
B7470_RS00100	COG0069	glutamate synthase activity
B7470_RS00105	COG0583	DNA-binding transcription factor activity
B7470_RS00135	COG0300	oxidoreductase activity
B7470_RS00140	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
B7470_RS00150	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B7470_RS00165	COG1131	(ABC) transporter
B7470_RS00175	COG2814	Major facilitator Superfamily
B7470_RS00180	COG3328	transposase activity
B7470_RS00220	COG3328	transposase activity
B7470_RS00275	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B7470_RS00280	COG2226	methyltransferase
B7470_RS00285	COG2211	Major facilitator Superfamily
B7470_RS00290	COG3328	transposase activity
B7470_RS00315	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B7470_RS00335	COG5444	nuclease activity
B7470_RS00340	COG4282	regulation of fungal-type cell wall biogenesis
B7470_RS00345	COG1231	oxidoreductase activity
B7470_RS00350	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B7470_RS00355	COG0662	Cupin 2, conserved barrel domain protein
B7470_RS00355	COG2207	Transcriptional regulator
B7470_RS00360	COG0456	acetyltransferase
B7470_RS00365	COG1309	transcriptional regulator
B7470_RS00370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B7470_RS00375	COG3708	Transcriptional regulator
B7470_RS00380	COG2378	regulation of single-species biofilm formation
B7470_RS00390	COG0640	Transcriptional regulator
B7470_RS00395	COG0741	lytic transglycosylase activity
B7470_RS00400	COG2322	membrane
B7470_RS00415	COG1619	proteins homologs of microcin C7 resistance protein MccF
B7470_RS00420	COG3239	Fatty acid desaturase
B7470_RS00425	COG4585	Histidine kinase
B7470_RS00430	COG2197	response regulator
B7470_RS00435	COG3584	3D domain protein
B7470_RS00435	COG1388	LysM domain
B7470_RS00440	COG0514	ATP-dependent DNA helicase (RecQ)
B7470_RS00455	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B7470_RS00460	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B7470_RS00475	COG0071	Belongs to the small heat shock protein (HSP20) family
B7470_RS00500	COG1012	belongs to the aldehyde dehydrogenase family
B7470_RS00505	COG1657	PFAM Prenyltransferase squalene oxidase
B7470_RS00510	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B7470_RS00515	COG0733	neurotransmitter:sodium symporter activity
B7470_RS00520	COG0385	Bile acid
B7470_RS00525	COG0508	dehydrogenase complex catalyzes the overall conversion of
B7470_RS00530	COG0567	Dehydrogenase, E1 component
B7470_RS00535	COG4548	von Willebrand factor, type A
B7470_RS00540	COG0714	Associated with various cellular activities
B7470_RS00545	COG2032	superoxide dismutase activity
B7470_RS00550	COG0791	NLP P60 protein
B7470_RS00550	COG1388	LysM domain
B7470_RS00555	COG1819	glycosyl
B7470_RS00560	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
B7470_RS00565	COG0534	Mate efflux family protein
B7470_RS00570	COG1366	Belongs to the anti-sigma-factor antagonist family
B7470_RS00575	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B7470_RS00580	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B7470_RS00590	COG2962	Rard protein
B7470_RS00610	COG1942	4-Oxalocrotonate Tautomerase
B7470_RS00615	COG1733	regulation of RNA biosynthetic process
B7470_RS00620	COG0778	Nitroreductase
B7470_RS00630	COG0400	carboxylic ester hydrolase activity
B7470_RS00645	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B7470_RS00650	COG3409	Peptidoglycan-binding domain 1 protein
B7470_RS00650	COG0793	Belongs to the peptidase S41A family
B7470_RS00655	COG2226	methyltransferase
B7470_RS00665	COG1876	peptidase activity
B7470_RS00670	COG0813	purine-nucleoside phosphorylase activity
B7470_RS00685	COG0671	phosphoesterase, PA-phosphatase related
B7470_RS00710	COG4479	Belongs to the UPF0346 family
B7470_RS00720	COG1509	lysine 2,3-aminomutase activity
B7470_RS00725	COG0456	acetyltransferase
B7470_RS00730	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B7470_RS00735	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B7470_RS00740	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
B7470_RS00745	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B7470_RS00755	COG0456	acetyltransferase
B7470_RS00760	COG0463	Glycosyl transferase, family 2
B7470_RS00775	COG4641	Protein conserved in bacteria
B7470_RS00780	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
B7470_RS00785	COG1086	Polysaccharide biosynthesis protein
B7470_RS00790	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B7470_RS00795	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B7470_RS00800	COG1846	Transcriptional regulator
B7470_RS00805	COG0534	Mate efflux family protein
B7470_RS00815	COG4698	Protein conserved in bacteria
B7470_RS00825	COG1999	signal sequence binding
B7470_RS00835	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B7470_RS00840	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
B7470_RS00845	COG1272	protein, Hemolysin III
B7470_RS00850	COG0204	Acyl-transferase
B7470_RS00855	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
B7470_RS00860	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
B7470_RS00870	COG2136	Putative SAM-dependent methyltransferase
B7470_RS00870	COG2521	methyltransferase
B7470_RS00880	COG0129	dihydroxy-acid dehydratase activity
B7470_RS00885	COG1413	lyase activity
B7470_RS00890	COG1418	mRNA catabolic process
B7470_RS00895	COG0386	Belongs to the glutathione peroxidase family
B7470_RS00900	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
B7470_RS00905	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B7470_RS00910	COG1278	Cold shock
B7470_RS00930	COG0328	RNA-DNA hybrid ribonuclease activity
B7470_RS00935	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
B7470_RS00940	COG0328	RNA-DNA hybrid ribonuclease activity
B7470_RS00950	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B7470_RS00965	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
B7470_RS00975	COG1755	Isoprenylcysteine carboxyl methyltransferase
B7470_RS00980	COG3424	synthase
B7470_RS00985	COG2233	PERMEase
B7470_RS00990	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B7470_RS00995	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
B7470_RS01005	COG0800	Aldolase
B7470_RS01010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B7470_RS01015	COG1609	Transcriptional regulator
B7470_RS01020	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
B7470_RS01025	COG1028	Short-chain dehydrogenase reductase Sdr
B7470_RS01030	COG1199	ATP-dependent helicase activity
B7470_RS01045	COG0116	Belongs to the methyltransferase superfamily
B7470_RS01060	COG4474	Belongs to the UPF0398 family
B7470_RS01070	COG3359	exonuclease
B7470_RS01075	COG1205	dead DEAH box helicase
B7470_RS01075	COG1111	helicase
B7470_RS01080	COG2190	(PTS) system
B7470_RS01085	COG0071	Belongs to the small heat shock protein (HSP20) family
B7470_RS01120	COG3331	DNA recombination
B7470_RS01125	COG4499	WXG100 protein secretion system (Wss), protein YukC
B7470_RS01125	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B7470_RS01135	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
B7470_RS01140	COG3935	DnaD domain protein
B7470_RS01145	COG0017	Asparaginyl-tRNA synthetase
B7470_RS01150	COG0436	Aminotransferase
B7470_RS01155	COG5353	protein conserved in bacteria
B7470_RS01165	COG1199	ATP-dependent helicase activity
B7470_RS01165	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B7470_RS01170	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
B7470_RS01175	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
B7470_RS01180	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
B7470_RS01185	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
B7470_RS01185	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
B7470_RS01190	COG0617	tRNA 3'-terminal CCA addition
B7470_RS01195	COG0438	transferase activity, transferring glycosyl groups
B7470_RS01200	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B7470_RS01205	COG1803	Methylglyoxal synthase
B7470_RS01210	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
B7470_RS01215	COG1694	Mazg nucleotide pyrophosphohydrolase
B7470_RS01220	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B7470_RS01230	COG4347	Protein of unknown function (DUF1405)
B7470_RS01235	COG2010	Cytochrome c
B7470_RS01235	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B7470_RS01240	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B7470_RS01245	COG0723	plastoquinol--plastocyanin reductase activity
B7470_RS01255	COG5582	Belongs to the UPF0302 family
B7470_RS01260	COG0457	Tetratricopeptide repeat
B7470_RS01265	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
B7470_RS01270	COG0287	Prephenate dehydrogenase
B7470_RS01285	COG0133	tryptophan synthase activity
B7470_RS01290	COG0135	phosphoribosylanthranilate isomerase activity
B7470_RS01300	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B7470_RS01305	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B7470_RS01310	COG4401	Chorismate mutase type I
B7470_RS01315	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
B7470_RS01320	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
B7470_RS01325	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
B7470_RS01330	COG0105	UTP biosynthetic process
B7470_RS01335	COG0142	geranyltranstransferase activity
B7470_RS01340	COG2226	methyltransferase
B7470_RS01345	COG0142	geranyltranstransferase activity
B7470_RS01355	COG0302	gtp cyclohydrolase
B7470_RS01360	COG0776	regulation of translation
B7470_RS01365	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
B7470_RS01380	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
B7470_RS01385	COG1160	GTP binding
B7470_RS01410	COG1304	FMN binding
B7470_RS01415	COG0539	negative regulation of cytoplasmic translation
B7470_RS01420	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
B7470_RS01430	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
B7470_RS01435	COG2959	enzyme of heme biosynthesis
B7470_RS01440	COG3773	Cell wall hydrolase
B7470_RS01440	COG3409	Peptidoglycan-binding domain 1 protein
B7470_RS01445	COG2339	peptidase activity
B7470_RS01450	COG0492	ferredoxin-NADP+ reductase activity
B7470_RS01455	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B7470_RS01460	COG4862	establishment of competence for transformation
B7470_RS01465	COG1408	metallophosphoesterase
B7470_RS01475	COG1388	LysM domain
B7470_RS01480	COG1266	CAAX protease self-immunity
B7470_RS01485	COG0514	ATP-dependent DNA helicase (RecQ)
B7470_RS01490	COG4955	Helix-turn-helix domain
B7470_RS01495	COG1141	Ferredoxin
B7470_RS01500	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
B7470_RS01505	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B7470_RS01510	COG0710	3-dehydroquinate dehydratase activity
B7470_RS01520	COG1595	DNA-templated transcription, initiation
B7470_RS01525	COG5002	protein histidine kinase activity
B7470_RS01530	COG0745	RESPONSE REGULATOR receiver
B7470_RS01535	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B7470_RS01540	COG1333	cytochrome c biogenesis protein
B7470_RS01545	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B7470_RS01550	COG1187	pseudouridine synthase activity
B7470_RS01555	COG0700	Nucleoside recognition
B7470_RS01560	COG2715	membrane protein required for spore maturation
B7470_RS01565	COG1686	Belongs to the peptidase S11 family
B7470_RS01575	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
B7470_RS01580	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
B7470_RS01585	COG1547	Domain of unknown function (DUF309)
B7470_RS01590	COG0456	acetyltransferase
B7470_RS01595	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
B7470_RS01600	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B7470_RS01600	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B7470_RS01605	COG0307	riboflavin synthase, alpha
B7470_RS01610	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B7470_RS01610	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B7470_RS01620	COG0681	Belongs to the peptidase S26 family
B7470_RS01630	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
B7470_RS01680	COG3328	transposase activity
B7470_RS01730	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
B7470_RS01745	COG4086	secreted protein
B7470_RS01750	COG0019	diaminopimelate decarboxylase activity
B7470_RS01755	COG0697	spore germination
B7470_RS01770	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B7470_RS01790	COG1191	sigma factor activity
B7470_RS01795	COG2172	sigma factor antagonist activity
B7470_RS01800	COG1366	Belongs to the anti-sigma-factor antagonist family
B7470_RS01805	COG1686	Belongs to the peptidase S11 family
B7470_RS01810	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
B7470_RS01815	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
B7470_RS01820	COG4974	Belongs to the 'phage' integrase family
B7470_RS01830	COG0735	belongs to the Fur family
B7470_RS01835	COG1300	Membrane
B7470_RS01845	COG0281	malic enzyme
B7470_RS01850	COG1757	Na H antiporter
B7470_RS01855	COG1027	Aspartate ammonia-lyase
B7470_RS01860	COG0252	asparaginase activity
B7470_RS01865	COG1396	sequence-specific DNA binding
B7470_RS01870	COG1379	DNA repair
B7470_RS01875	COG0494	nUDIX hydrolase
B7470_RS01885	COG0667	Aldo Keto reductase
B7470_RS01895	COG1073	alpha beta
B7470_RS01905	COG4918	Iron-sulphur cluster biosynthesis
B7470_RS01910	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
B7470_RS01910	COG0456	acetyltransferase
B7470_RS01915	COG2329	Antibiotic biosynthesis monooxygenase
B7470_RS01920	COG0456	acetyltransferase
B7470_RS01930	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B7470_RS01940	COG2211	Major facilitator Superfamily
B7470_RS01950	COG0346	lactoylglutathione lyase activity
B7470_RS01955	COG1072	(Pantothenic acid kinase))
B7470_RS01960	COG3048	D-serine ammonia-lyase activity
B7470_RS01965	COG0300	oxidoreductase activity
B7470_RS01970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B7470_RS01975	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B7470_RS01980	COG4187	Peptidase family M20/M25/M40
B7470_RS01985	COG1902	pentaerythritol trinitrate reductase activity
B7470_RS02000	COG0596	Alpha beta hydrolase
B7470_RS02010	COG1234	tRNA 3'-trailer cleavage
B7470_RS02015	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
B7470_RS02020	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
B7470_RS02025	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B7470_RS02035	COG0706	membrane insertase activity
B7470_RS02040	COG3361	conserved protein (COG2071)
B7470_RS02045	COG2195	Cleaves the N-terminal amino acid of tripeptides
B7470_RS02055	COG0346	lactoylglutathione lyase activity
B7470_RS02060	COG1376	ErfK ybiS ycfS ynhG family protein
B7470_RS02065	COG4129	membrane
B7470_RS02070	COG1126	abc transporter atp-binding protein
B7470_RS02075	COG0765	amino acid transport
B7470_RS02080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7470_RS02090	COG1597	lipid kinase activity
B7470_RS02100	COG0789	Transcriptional regulator
B7470_RS02100	COG4978	Transcriptional regulator
B7470_RS02105	COG0508	dehydrogenase complex catalyzes the overall conversion of
B7470_RS02110	COG0022	dehydrogenase e1 component
B7470_RS02120	COG3426	butyrate kinase activity
B7470_RS02125	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B7470_RS02130	COG0280	phosphate acetyltransferase
B7470_RS02135	COG3290	protein histidine kinase activity
B7470_RS02135	COG3829	transcription factor binding
B7470_RS02145	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
B7470_RS02150	COG2079	MmgE PrpD family protein
B7470_RS02155	COG0372	Belongs to the citrate synthase family
B7470_RS02160	COG1960	acyl-CoA dehydrogenase activity
B7470_RS02165	COG1250	3-hydroxyacyl-CoA dehydrogenase
B7470_RS02170	COG0183	Belongs to the thiolase family
B7470_RS02175	COG0584	glycerophosphoryl diester phosphodiesterase
B7470_RS02180	COG0860	N-Acetylmuramoyl-L-alanine amidase
B7470_RS02190	COG1902	pentaerythritol trinitrate reductase activity
B7470_RS02195	COG0745	RESPONSE REGULATOR receiver
B7470_RS02205	COG0750	zinc metalloprotease
B7470_RS02210	COG0497	DNA recombination
B7470_RS02215	COG1438	arginine binding
B7470_RS02220	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
B7470_RS02225	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
B7470_RS02230	COG0142	geranyltranstransferase activity
B7470_RS02235	COG1722	exodeoxyribonuclease VII activity
B7470_RS02240	COG1570	exodeoxyribonuclease VII activity
B7470_RS02245	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
B7470_RS02250	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B7470_RS02255	COG1302	Protein conserved in bacteria
B7470_RS02260	COG0439	Biotin carboxylase
B7470_RS02265	COG0511	ligase activity, forming carbon-carbon bonds
B7470_RS02310	COG3854	ATPases associated with a variety of cellular activities
B7470_RS02320	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
B7470_RS02325	COG0006	proline dipeptidase activity
B7470_RS02330	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
B7470_RS02340	COG3872	metal-dependent enzyme
B7470_RS02350	COG1752	Esterase of the alpha-beta hydrolase superfamily
B7470_RS02355	COG1321	iron dependent repressor
B7470_RS02360	COG0095	Lipoate-protein ligase
B7470_RS02365	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B7470_RS02370	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B7470_RS02375	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B7470_RS02380	COG0404	The glycine cleavage system catalyzes the degradation of glycine
B7470_RS02385	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B7470_RS02400	COG1396	sequence-specific DNA binding
B7470_RS02410	COG0681	Belongs to the peptidase S26 family
B7470_RS02435	COG4940	Competence protein ComGF
B7470_RS02445	COG4970	Tfp pilus assembly protein FimT
B7470_RS02450	COG4537	Required for transformation and DNA binding
B7470_RS02455	COG1459	type II secretion system
B7470_RS02460	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
B7470_RS02465	COG0517	IMP dehydrogenase activity
B7470_RS02470	COG0598	Magnesium transport protein CorA
B7470_RS02475	COG1253	flavin adenine dinucleotide binding
B7470_RS02480	COG1366	Belongs to the anti-sigma-factor antagonist family
B7470_RS02490	COG1393	Belongs to the ArsC family
B7470_RS02500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B7470_RS02510	COG0011	TIGRFAM Protein of
B7470_RS02520	COG2866	Carboxypeptidase
B7470_RS02525	COG1368	sulfuric ester hydrolase activity
B7470_RS02530	COG1940	carbohydrate kinase activity
B7470_RS02535	COG4483	Protein conserved in bacteria
B7470_RS02540	COG0705	Rhomboid family
B7470_RS02540	COG0457	Tetratricopeptide repeat
B7470_RS02550	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
B7470_RS02560	COG0438	transferase activity, transferring glycosyl groups
B7470_RS02575	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B7470_RS02580	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B7470_RS02585	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B7470_RS02590	COG0581	inorganic phosphate transmembrane transporter activity
B7470_RS02595	COG0573	inorganic phosphate transmembrane transporter activity
B7470_RS02600	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B7470_RS02610	COG0477	Major facilitator Superfamily
B7470_RS02615	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B7470_RS02620	COG2839	Protein conserved in bacteria
B7470_RS02625	COG5521	maltodextrose utilization protein MalA
B7470_RS02630	COG1388	LysM domain
B7470_RS02635	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
B7470_RS02640	COG4709	membrane
B7470_RS02645	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
B7470_RS02650	COG0735	belongs to the Fur family
B7470_RS02655	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B7470_RS02665	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
B7470_RS02670	COG0513	Belongs to the DEAD box helicase family
B7470_RS02680	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
B7470_RS02685	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
B7470_RS02690	COG2384	SAM-dependent methyltransferase
B7470_RS02695	COG2010	Cytochrome c
B7470_RS02705	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B7470_RS02710	COG0358	DNA primase activity
B7470_RS02715	COG1671	Belongs to the UPF0178 family
B7470_RS02720	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
B7470_RS02725	COG0517	IMP dehydrogenase activity
B7470_RS02730	COG0751	glycine-tRNA ligase activity
B7470_RS02735	COG0752	glycyl-tRNA synthetase alpha subunit
B7470_RS02740	COG1381	Involved in DNA repair and RecF pathway recombination
B7470_RS02750	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
B7470_RS02755	COG0295	cytidine deaminase activity
B7470_RS02760	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
B7470_RS02765	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
B7470_RS02770	COG1480	7TM receptor with intracellular HD hydrolase
B7470_RS02775	COG1702	phosphate starvation-inducible protein PhoH
B7470_RS02780	COG0561	phosphatase activity
B7470_RS02795	COG4864	UPF0365 protein
B7470_RS02800	COG1030	water channel activity
B7470_RS02805	COG1610	YqeY-like protein
B7470_RS02815	COG1283	sodium-dependent phosphate transmembrane transporter activity
B7470_RS02820	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B7470_RS02825	COG1385	rRNA (uridine-N3-)-methyltransferase activity
B7470_RS02830	COG2264	protein methyltransferase activity
B7470_RS02835	COG0484	heat shock protein binding
B7470_RS02840	COG0443	Heat shock 70 kDa protein
B7470_RS02845	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
B7470_RS02850	COG1420	regulation of RNA biosynthetic process
B7470_RS02855	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B7470_RS02860	COG0481	GTPase activity
B7470_RS02870	COG0860	N-Acetylmuramoyl-L-alanine amidase
B7470_RS02875	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
B7470_RS02880	COG0268	Binds directly to 16S ribosomal RNA
B7470_RS02885	COG1466	dna polymerase III delta subunit
B7470_RS02895	COG2333	competence protein COMEC
B7470_RS02895	COG0658	competence protein
B7470_RS02900	COG2131	deaminase
B7470_RS02905	COG1555	photosystem II stabilization
B7470_RS02905	COG1596	polysaccharide export
B7470_RS02910	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B7470_RS02915	COG2226	methyltransferase
B7470_RS02920	COG0799	negative regulation of ribosome biogenesis
B7470_RS02925	COG1713	HD superfamily hydrolase involved in NAD metabolism
B7470_RS02930	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
B7470_RS02935	COG1534	Rna-binding protein
B7470_RS02940	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B7470_RS02945	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
B7470_RS02950	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
B7470_RS02960	COG2755	lipolytic protein G-D-S-L family
B7470_RS02965	COG3409	Peptidoglycan-binding domain 1 protein
B7470_RS02965	COG5632	N-Acetylmuramoyl-L-alanine amidase
B7470_RS02970	COG0398	Pfam SNARE associated Golgi protein
B7470_RS02975	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
B7470_RS02985	COG3209	COG3209 Rhs family protein
B7470_RS03000	COG0114	fumarate hydratase activity
B7470_RS03005	COG0583	DNA-binding transcription factor activity
B7470_RS03020	COG0457	Tetratricopeptide repeat
B7470_RS03140	COG4978	Transcriptional regulator
B7470_RS03140	COG0789	Transcriptional regulator
B7470_RS03145	COG2814	Major facilitator Superfamily
B7470_RS03150	COG0456	acetyltransferase
B7470_RS03155	COG1253	flavin adenine dinucleotide binding
B7470_RS03165	COG0697	spore germination
B7470_RS03170	COG0583	DNA-binding transcription factor activity
B7470_RS03175	COG2072	flavoprotein involved in K transport
B7470_RS03180	COG1230	cation diffusion facilitator family transporter
B7470_RS03190	COG1114	Component of the transport system for branched-chain amino acids
B7470_RS03195	COG1687	branched-chain amino acid
B7470_RS03205	COG1522	sequence-specific DNA binding
B7470_RS03210	COG2732	(Barnase) inhibitor
B7470_RS03215	COG2124	cytochrome p450
B7470_RS03225	COG1335	isochorismatase
B7470_RS03235	COG2318	DinB family
B7470_RS03245	COG2070	2-Nitropropane dioxygenase
B7470_RS03260	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
B7470_RS03275	COG3443	Belongs to the bacterial solute-binding protein 9 family
B7470_RS03280	COG1595	DNA-templated transcription, initiation
B7470_RS03285	COG0667	Aldo Keto reductase
B7470_RS03290	COG3409	Peptidoglycan-binding domain 1 protein
B7470_RS03295	COG5566	PFAM Mor transcription activator
B7470_RS03305	COG4991	sh3 domain protein
B7470_RS03310	COG4991	sh3 domain protein
B7470_RS03315	COG0346	lactoylglutathione lyase activity
B7470_RS03325	COG5577	PFAM Coat F domain
B7470_RS03330	COG1063	alcohol dehydrogenase
B7470_RS03340	COG5577	PFAM Coat F domain
B7470_RS03345	COG0789	Transcriptional regulator
B7470_RS03355	COG1064	alcohol dehydrogenase
B7470_RS03360	COG0693	protein deglycase activity
B7470_RS03365	COG1621	beta-fructofuranosidase activity
B7470_RS03370	COG3716	PTS system mannose fructose sorbose family IID component
B7470_RS03375	COG3715	PTS system
B7470_RS03380	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B7470_RS03385	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7470_RS03390	COG3933	PFAM sigma-54 factor interaction domain-containing protein
B7470_RS03390	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
B7470_RS03395	COG1113	amino acid transport
B7470_RS03400	COG1280	lysine exporter protein (LysE YggA)
B7470_RS03405	COG1378	Sugar-specific transcriptional regulator TrmB
B7470_RS03410	COG1595	DNA-templated transcription, initiation
B7470_RS03435	COG1309	transcriptional regulator
B7470_RS03440	COG2226	methyltransferase
B7470_RS03450	COG2116	formate transmembrane transporter activity
B7470_RS03455	COG5609	conserved protein (DUF2294)
B7470_RS03460	COG3383	formate dehydrogenase (NAD+) activity
B7470_RS03465	COG2427	Protein of unknown function (DUF1641)
B7470_RS03480	COG0626	cystathionine gamma-synthase activity
B7470_RS03485	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B7470_RS03490	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B7470_RS03495	COG2226	methyltransferase
B7470_RS03510	COG0768	penicillin binding
B7470_RS03515	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B7470_RS03520	COG0572	uridine kinase
B7470_RS03535	COG4122	O-methyltransferase activity
B7470_RS03540	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B7470_RS03545	COG3906	Belongs to the UPF0473 family
B7470_RS03550	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
B7470_RS03555	COG4472	Bacterial protein of unknown function (DUF965)
B7470_RS03560	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
B7470_RS03565	COG0628	permease
B7470_RS03570	COG1126	abc transporter atp-binding protein
B7470_RS03575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7470_RS03580	COG0765	amino acid transport
B7470_RS03585	COG0765	amino acid transport
B7470_RS03600	COG3881	PFAM PRC-barrel domain
B7470_RS03605	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B7470_RS03610	COG0457	Tetratricopeptide repeat
B7470_RS03615	COG0482	sulfurtransferase activity
B7470_RS03620	COG1104	cysteine desulfurase activity
B7470_RS03625	COG1959	2 iron, 2 sulfur cluster binding
B7470_RS03630	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
B7470_RS03635	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
B7470_RS03645	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
B7470_RS03650	COG0124	histidyl-tRNA synthetase
B7470_RS03660	COG0860	N-Acetylmuramoyl-L-alanine amidase
B7470_RS03660	COG4991	sh3 domain protein
B7470_RS03660	COG3103	Sh3 type 3 domain protein
B7470_RS03665	COG1490	D-aminoacyl-tRNA deacylase activity
B7470_RS03670	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B7470_RS03675	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B7470_RS03680	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
B7470_RS03680	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
B7470_RS03685	COG5416	Lipopolysaccharide assembly protein A domain
B7470_RS03690	COG0490	domain, Protein
B7470_RS03695	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B7470_RS03695	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B7470_RS03705	COG2244	polysaccharide biosynthetic process
B7470_RS03710	COG2323	membrane
B7470_RS03720	COG1862	Preprotein translocase
B7470_RS03725	COG0343	queuine tRNA-ribosyltransferase activity
B7470_RS03730	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
B7470_RS03740	COG2255	four-way junction helicase activity
B7470_RS03745	COG0632	four-way junction helicase activity
B7470_RS03755	COG2814	Major facilitator Superfamily
B7470_RS03760	COG0673	inositol 2-dehydrogenase activity
B7470_RS03765	COG2112	serine threonine protein kinase
B7470_RS03780	COG1115	amino acid carrier protein
B7470_RS03785	COG0217	transcriptional regulatory protein
B7470_RS03795	COG1388	LysM domain
B7470_RS03800	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
B7470_RS03805	COG0157	Belongs to the NadC ModD family
B7470_RS03810	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
B7470_RS03815	COG1104	cysteine desulfurase activity
B7470_RS03820	COG1827	regulation of RNA biosynthetic process
B7470_RS03825	COG0077	Prephenate dehydratase
B7470_RS03830	COG4492	Belongs to the UPF0735 family
B7470_RS03835	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
B7470_RS03840	COG3290	protein histidine kinase activity
B7470_RS03845	COG0211	Belongs to the bacterial ribosomal protein bL27 family
B7470_RS03850	COG2868	ribosomal protein
B7470_RS03855	COG0261	This protein binds to 23S rRNA in the presence of protein L20
B7470_RS03860	COG1994	Peptidase M50
B7470_RS03865	COG0739	heme binding
B7470_RS03870	COG2894	cell division
B7470_RS03875	COG0850	regulation of cytokinetic process
B7470_RS03880	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
B7470_RS03890	COG1077	Cell shape determining protein MreB Mrl
B7470_RS03895	COG2003	Belongs to the UPF0758 family
B7470_RS03900	COG0424	maF-like protein
B7470_RS03910	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
B7470_RS03915	COG0285	dihydrofolate synthase activity
B7470_RS03920	COG0525	valine-tRNA ligase activity
B7470_RS03930	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
B7470_RS03935	COG1388	LysM domain
B7470_RS03940	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
B7470_RS03945	COG0113	porphobilinogen synthase activity
B7470_RS03950	COG1587	Uroporphyrinogen-III synthase
B7470_RS03955	COG0181	hydroxymethylbilane synthase activity
B7470_RS03960	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B7470_RS03965	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
B7470_RS03975	COG0218	Necessary for normal cell division and for the maintenance of normal septation
B7470_RS03980	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
B7470_RS03985	COG0470	DNA polymerase III
B7470_RS03985	COG1067	ATP-dependent peptidase activity
B7470_RS03990	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
B7470_RS03995	COG0544	peptidyl-prolyl cis-trans isomerase activity
B7470_RS04000	COG1477	protein flavinylation
B7470_RS04000	COG0457	Tetratricopeptide repeat
B7470_RS04005	COG0066	3-isopropylmalate dehydratase activity
B7470_RS04010	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
B7470_RS04015	COG0473	3-isopropylmalate dehydrogenase activity
B7470_RS04020	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B7470_RS04025	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
B7470_RS04030	COG0440	acetolactate synthase activity
B7470_RS04035	COG0028	Belongs to the TPP enzyme family
B7470_RS04050	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
B7470_RS04080	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
B7470_RS04105	COG0622	Phosphoesterase
B7470_RS04110	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
B7470_RS04115	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
B7470_RS04120	COG5401	PFAM Sporulation and spore germination
B7470_RS04125	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
B7470_RS04130	COG1846	Transcriptional regulator
B7470_RS04135	COG2197	response regulator
B7470_RS04140	COG0824	Thioesterase
B7470_RS04145	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B7470_RS04150	COG1053	succinate dehydrogenase
B7470_RS04155	COG2009	succinate dehydrogenase
B7470_RS04160	COG1719	4-vinyl reductase, 4VR
B7470_RS04165	COG0527	aspartate kinase activity
B7470_RS04175	COG0322	excinuclease ABC activity
B7470_RS04180	COG3118	belongs to the thioredoxin family
B7470_RS04185	COG3534	alpha-L-arabinofuranosidase
B7470_RS04190	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
B7470_RS04195	COG2086	electron transfer activity
B7470_RS04200	COG1024	Enoyl-CoA hydratase
B7470_RS04205	COG1309	transcriptional regulator
B7470_RS04210	COG0318	PFAM AMP-dependent synthetase and ligase
B7470_RS04215	COG3766	membrane
B7470_RS04220	COG1193	negative regulation of DNA recombination
B7470_RS04225	COG1796	DNA polymerase
B7470_RS04225	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
B7470_RS04230	COG1286	toxin biosynthetic process
B7470_RS04235	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
B7470_RS04240	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
B7470_RS04245	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B7470_RS04245	COG0072	phenylalanine-tRNA ligase activity
B7470_RS04250	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
B7470_RS04260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B7470_RS04270	COG3835	regulator
B7470_RS04275	COG0277	FAD linked oxidase domain protein
B7470_RS04280	COG0247	lactate metabolic process
B7470_RS04285	COG0346	lactoylglutathione lyase activity
B7470_RS04290	COG1966	Carbon starvation protein
B7470_RS04295	COG3534	alpha-L-arabinofuranosidase
B7470_RS04300	COG0395	ABC-type sugar transport system, permease component
B7470_RS04305	COG1175	transmembrane transport
B7470_RS04310	COG1653	transport
B7470_RS04315	COG0371	Dehydrogenase
B7470_RS04320	COG0647	UMP catabolic process
B7470_RS04325	COG0235	Class ii aldolase
B7470_RS04330	COG1069	ribulokinase activity
B7470_RS04335	COG2160	L-arabinose isomerase activity
B7470_RS04345	COG1363	Peptidase, m42
B7470_RS04355	COG3326	Membrane
B7470_RS04360	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
B7470_RS04365	COG0291	Belongs to the bacterial ribosomal protein bL35 family
B7470_RS04370	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
B7470_RS04380	COG1346	cytolysis
B7470_RS04385	COG1380	Effector of murein hydrolase LrgA
B7470_RS04390	COG3279	Response regulator of the LytR AlgR family
B7470_RS04395	COG3275	phosphorelay sensor kinase activity
B7470_RS04400	COG1011	Hydrolase
B7470_RS04405	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
B7470_RS04415	COG0398	Pfam SNARE associated Golgi protein
B7470_RS04420	COG1484	DNA-dependent DNA replication
B7470_RS04425	COG3611	Membrane attachment protein
B7470_RS04430	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
B7470_RS04435	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
B7470_RS04440	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B7470_RS04445	COG1733	regulation of RNA biosynthetic process
B7470_RS04450	COG2814	Major facilitator Superfamily
B7470_RS04455	COG0656	L-ascorbic acid biosynthetic process
B7470_RS04460	COG0237	dephospho-CoA kinase activity
B7470_RS04465	COG1971	Probably functions as a manganese efflux pump
B7470_RS04470	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B7470_RS04475	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B7470_RS04475	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B7470_RS04480	COG5002	protein histidine kinase activity
B7470_RS04485	COG0745	RESPONSE REGULATOR receiver
B7470_RS04490	COG0039	L-malate dehydrogenase activity
B7470_RS04495	COG0538	isocitrate dehydrogenase activity
B7470_RS04500	COG0372	Belongs to the citrate synthase family
B7470_RS04505	COG2707	UPF0756 membrane protein
B7470_RS04510	COG0628	permease
B7470_RS04515	COG3030	protein affecting phage T7 exclusion by the F plasmid
B7470_RS04520	COG0469	pyruvate kinase activity
B7470_RS04525	COG0205	6-phosphofructokinase activity
B7470_RS04530	COG0825	malonyl-CoA metabolic process
B7470_RS04535	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
B7470_RS04540	COG0281	malic enzyme
B7470_RS04545	COG0587	DNA-directed DNA polymerase activity
B7470_RS04565	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
B7470_RS04575	COG4109	DRTGG domain
B7470_RS04585	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B7470_RS04590	COG1028	Short-chain dehydrogenase reductase Sdr
B7470_RS04600	COG0165	Argininosuccinate lyase
B7470_RS04605	COG0137	argininosuccinate synthase activity
B7470_RS04610	COG0521	Mo-molybdopterin cofactor biosynthetic process
B7470_RS04615	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
B7470_RS04625	COG0827	DNA restriction-modification system
B7470_RS04630	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
B7470_RS04635	COG3874	Sporulation protein YtfJ
B7470_RS04645	COG1714	RDD family
B7470_RS04650	COG0616	signal peptide processing
B7470_RS04655	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
B7470_RS04660	COG1574	metal-dependent hydrolase with the TIM-barrel fold
B7470_RS04665	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B7470_RS04675	COG0301	tRNA thio-modification
B7470_RS04680	COG1104	cysteine desulfurase activity
B7470_RS04685	COG1114	Component of the transport system for branched-chain amino acids
B7470_RS04690	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
B7470_RS04695	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
B7470_RS04700	COG1309	transcriptional regulator
B7470_RS04705	COG1956	GAF domain-containing protein
B7470_RS04710	COG2203	Gaf domain
B7470_RS04710	COG2199	diguanylate cyclase activity
B7470_RS04720	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
B7470_RS04725	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
B7470_RS04735	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B7470_RS04740	COG0454	-acetyltransferase
B7470_RS04745	COG0517	IMP dehydrogenase activity
B7470_RS04750	COG0123	including yeast histone deacetylase and acetoin utilization protein
B7470_RS04755	COG1360	Flagellar Motor Protein
B7470_RS04760	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
B7470_RS04765	COG1609	Transcriptional regulator
B7470_RS04770	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
B7470_RS04770	COG1605	Chorismate mutase
B7470_RS04775	COG3118	belongs to the thioredoxin family
B7470_RS04780	COG4980	gas vesicle protein
B7470_RS04785	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
B7470_RS04790	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B7470_RS04795	COG1674	ftsk spoiiie
B7470_RS04800	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B7470_RS04805	COG4848	Belongs to the UPF0354 family
B7470_RS04810	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B7470_RS04820	COG1363	Peptidase, m42
B7470_RS04825	COG5584	Small secreted protein
B7470_RS04830	COG0281	malic enzyme
B7470_RS04835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B7470_RS04840	COG0220	tRNA (guanine-N7-)-methyltransferase activity
B7470_RS04850	COG0510	thiamine kinase activity
B7470_RS04855	COG1523	belongs to the glycosyl hydrolase 13 family
B7470_RS04860	COG1597	lipid kinase activity
B7470_RS04870	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
B7470_RS04875	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B7470_RS04880	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B7470_RS04885	COG2252	PERMEase
B7470_RS04890	COG4473	ABC transporter
B7470_RS04895	COG1131	(ABC) transporter
B7470_RS04900	COG1349	DNA-binding transcription factor activity
B7470_RS04905	COG1187	pseudouridine synthase activity
B7470_RS04910	COG2244	polysaccharide biosynthetic process
B7470_RS04915	COG2081	HI0933 family
B7470_RS04920	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B7470_RS04940	COG1653	transport
B7470_RS04945	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
B7470_RS04950	COG4209	transmembrane transport
B7470_RS04960	COG1653	transport
B7470_RS04965	COG0395	ABC-type sugar transport system, permease component
B7470_RS04970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B7470_RS04975	COG2124	cytochrome p450
B7470_RS04995	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B7470_RS05005	COG1073	alpha beta
B7470_RS05010	COG1609	Transcriptional regulator
B7470_RS05015	COG1653	transport
B7470_RS05020	COG1175	transmembrane transport
B7470_RS05025	COG0395	ABC-type sugar transport system, permease component
B7470_RS05030	COG1486	melibiose metabolic process
B7470_RS05035	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B7470_RS05040	COG0495	leucyl-tRNA aminoacylation
B7470_RS05050	COG2202	Pas domain
B7470_RS05050	COG1366	Belongs to the anti-sigma-factor antagonist family
B7470_RS05055	COG2814	Major facilitator Superfamily
B7470_RS05060	COG2433	Pfam Transposase IS66
B7470_RS05065	COG0577	efflux transmembrane transporter activity
B7470_RS05070	COG1136	(ABC) transporter
B7470_RS05075	COG2205	protein histidine kinase activity
B7470_RS05080	COG0745	RESPONSE REGULATOR receiver
B7470_RS05085	COG0577	efflux transmembrane transporter activity
B7470_RS05090	COG1136	(ABC) transporter
B7470_RS05105	COG1131	(ABC) transporter
B7470_RS05110	COG1725	Transcriptional regulator
B7470_RS05120	COG1242	4 iron, 4 sulfur cluster binding
B7470_RS05125	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
B7470_RS05135	COG2267	carboxylic ester hydrolase activity
B7470_RS05140	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
B7470_RS05145	COG1113	amino acid transport
B7470_RS05150	COG0367	asparagine synthase
B7470_RS05155	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
B7470_RS05160	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
B7470_RS05170	COG1506	peptidase
B7470_RS05175	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B7470_RS05180	COG1116	anion transmembrane transporter activity
B7470_RS05185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B7470_RS05190	COG0494	nUDIX hydrolase
B7470_RS05195	COG4824	toxin secretion phage lysis holin
B7470_RS05200	COG0783	Belongs to the Dps family
B7470_RS05215	COG1854	S-ribosylhomocysteine lyase activity
B7470_RS05220	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
B7470_RS05225	COG0288	reversible hydration of carbon dioxide
B7470_RS05230	COG0254	rRNA binding
B7470_RS05235	COG1271	oxidase subunit
B7470_RS05240	COG1294	oxidase, subunit
B7470_RS05250	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B7470_RS05255	COG1321	iron dependent repressor
B7470_RS05255	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B7470_RS05260	COG1121	(ABC) transporter
B7470_RS05265	COG0803	Belongs to the bacterial solute-binding protein 9 family
B7470_RS05270	COG4948	Mandelate Racemase Muconate Lactonizing
B7470_RS05275	COG0318	PFAM AMP-dependent synthetase and ligase
B7470_RS05280	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
B7470_RS05285	COG0596	Alpha beta hydrolase
B7470_RS05290	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
B7470_RS05295	COG1169	isochorismate synthase
B7470_RS05305	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B7470_RS05310	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B7470_RS05315	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
B7470_RS05320	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B7470_RS05325	COG0438	transferase activity, transferring glycosyl groups
B7470_RS05335	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
B7470_RS05340	COG0438	transferase activity, transferring glycosyl groups
B7470_RS05345	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
B7470_RS05350	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
B7470_RS05355	COG0058	SHG alpha-glucan phosphorylase activity
B7470_RS05360	COG0297	glycogen (starch) synthase activity
B7470_RS05365	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
B7470_RS05370	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
B7470_RS05375	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
B7470_RS05500	COG3859	Proton-coupled thiamine transporter YuaJ
B7470_RS05505	COG1247	-acetyltransferase
B7470_RS05510	COG2268	Band 7 protein
B7470_RS05515	COG1585	Membrane protein implicated in regulation of membrane protease activity
B7470_RS05520	COG2318	DinB family
B7470_RS05530	COG1454	alcohol dehydrogenase
B7470_RS05535	COG1012	belongs to the aldehyde dehydrogenase family
B7470_RS05540	COG1510	regulation of RNA biosynthetic process
B7470_RS05550	COG0569	domain protein
B7470_RS05555	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B7470_RS05560	COG4682	membrane
B7470_RS05565	COG1705	Flagellar rod assembly protein muramidase FlgJ
B7470_RS05570	COG0477	Major facilitator Superfamily
B7470_RS05575	COG5553	Cysteine dioxygenase type I
B7470_RS05585	COG1968	undecaprenyl-diphosphatase activity
B7470_RS05590	COG0628	permease
B7470_RS05595	COG0673	inositol 2-dehydrogenase activity
B7470_RS05600	COG4806	L-rhamnose isomerase
B7470_RS05605	COG3254	rhamnose metabolic process
B7470_RS05610	COG1070	Carbohydrate kinase
B7470_RS05615	COG1349	DNA-binding transcription factor activity
B7470_RS05620	COG3347	Dehydrogenase
B7470_RS05620	COG1028	Short-chain dehydrogenase reductase Sdr
B7470_RS05635	COG0840	transmembrane signaling receptor activity
B7470_RS05645	COG0840	transmembrane signaling receptor activity
B7470_RS05660	COG0432	Pfam Uncharacterised protein family UPF0047
B7470_RS05665	COG0366	Alpha amylase catalytic
B7470_RS05670	COG1253	flavin adenine dinucleotide binding
B7470_RS05675	COG2738	Putative neutral zinc metallopeptidase
B7470_RS05690	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B7470_RS05705	COG0166	Belongs to the GPI family
B7470_RS05710	COG1979	alcohol dehydrogenase
B7470_RS05715	COG1979	alcohol dehydrogenase
B7470_RS05720	COG2155	Conserved Protein
B7470_RS05725	COG1098	S1 RNA binding domain
B7470_RS05730	COG0436	Aminotransferase
B7470_RS05735	COG1522	sequence-specific DNA binding
B7470_RS05740	COG2267	carboxylic ester hydrolase activity
B7470_RS05750	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
B7470_RS05755	COG2205	protein histidine kinase activity
B7470_RS05765	COG5018	Exonuclease
B7470_RS05775	COG2814	Major facilitator Superfamily
B7470_RS05780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B7470_RS05785	COG3011	Protein conserved in bacteria
B7470_RS05795	COG3290	protein histidine kinase activity
B7470_RS05800	COG4565	transcriptional regulatory protein
B7470_RS05825	COG3493	citrate carrier protein
B7470_RS05835	COG2111	Na H antiporter
B7470_RS05835	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B7470_RS05840	COG2111	Na H antiporter
B7470_RS05845	COG1006	Multisubunit Na H antiporter MnhC subunit
B7470_RS05850	COG0651	ATP synthesis coupled electron transport
B7470_RS05855	COG1863	multisubunit Na H antiporter MnhE subunit
B7470_RS05860	COG2212	antiporter activity
B7470_RS05865	COG1320	monovalent cation:proton antiporter activity
B7470_RS05870	COG2050	protein possibly involved in aromatic compounds catabolism
B7470_RS05875	COG2197	response regulator
B7470_RS05880	COG4585	Histidine kinase
B7470_RS05890	COG0142	geranyltranstransferase activity
B7470_RS05905	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
B7470_RS05910	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
B7470_RS05915	COG1335	isochorismatase
B7470_RS05920	COG5506	Protein of unknown function (DUF1694)
B7470_RS05935	COG0628	permease
B7470_RS05950	COG1418	mRNA catabolic process
B7470_RS05955	COG1028	Short-chain dehydrogenase reductase Sdr
B7470_RS05965	COG1511	domain protein
B7470_RS05970	COG0433	COG0433 Predicted ATPase
B7470_RS05970	COG1674	ftsk spoiiie
B7470_RS05975	COG4499	WXG100 protein secretion system (Wss), protein YukC
B7470_RS05980	COG5417	Belongs to the EsaB family
B7470_RS05985	COG4842	Belongs to the WXG100 family
B7470_RS05995	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
B7470_RS05995	COG2508	Transcriptional regulator
B7470_RS06000	COG0686	Belongs to the AlaDH PNT family
B7470_RS06005	COG5634	Uncharacterized conserved protein (DUF2278)
B7470_RS06010	COG3251	PFAM MbtH domain protein
B7470_RS06015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7470_RS06020	COG1535	isochorismatase
B7470_RS06020	COG3433	isochorismatase activity
B7470_RS06025	COG1021	2,3-dihydroxybenzoate-AMP ligase
B7470_RS06030	COG1169	isochorismate synthase
B7470_RS06035	COG1028	Short-chain dehydrogenase reductase Sdr
B7470_RS06040	COG2819	hydrolase of the alpha beta superfamily
B7470_RS06045	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
B7470_RS06050	COG1268	BioY protein
B7470_RS06055	COG2056	Na+-H+ antiporter family
B7470_RS06060	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
B7470_RS06065	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
B7470_RS06070	COG3584	3D domain protein
B7470_RS06085	COG1252	NADH dehydrogenase
B7470_RS06090	COG0492	ferredoxin-NADP+ reductase activity
B7470_RS06100	COG0516	GMP reductase activity
B7470_RS06105	COG2808	Putative FMN-binding domain
B7470_RS06110	COG0456	acetyltransferase
B7470_RS06205	COG0582	viral genome integration into host DNA
B7470_RS06215	COG4974	Belongs to the 'phage' integrase family
B7470_RS06220	COG0316	Belongs to the HesB IscA family
B7470_RS06225	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
B7470_RS06230	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B7470_RS06235	COG4844	belongs to the
B7470_RS06240	COG1252	NADH dehydrogenase
B7470_RS06245	COG4837	Protein of unknown function (DUF1462)
B7470_RS06250	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
B7470_RS06255	COG1506	peptidase
B7470_RS06255	COG0823	Involved in the tonB-independent uptake of proteins
B7470_RS06255	COG4946	Tricorn protease homolog
B7470_RS06260	COG0083	homoserine kinase activity
B7470_RS06265	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
B7470_RS06270	COG0460	homoserine dehydrogenase
B7470_RS06275	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
B7470_RS06280	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
B7470_RS06285	COG0647	UMP catabolic process
B7470_RS06290	COG2445	Protein of unknown function DUF86
B7470_RS06295	COG4470	Protein conserved in bacteria
B7470_RS06305	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
B7470_RS06310	COG0739	heme binding
B7470_RS06320	COG3377	Domain of unknown function (DUF1805)
B7470_RS06325	COG0737	Belongs to the 5'-nucleotidase family
B7470_RS06330	COG0730	response to heat
B7470_RS06335	COG1801	Protein of unknown function DUF72
B7470_RS06345	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B7470_RS06350	COG2508	Transcriptional regulator
B7470_RS06355	COG2233	PERMEase
B7470_RS06360	COG2233	PERMEase
B7470_RS06365	COG3195	allantoin biosynthetic process
B7470_RS06365	COG3648	Uricase
B7470_RS06370	COG2351	hydroxyisourate hydrolase activity
B7470_RS06380	COG2080	2 iron, 2 sulfur cluster binding
B7470_RS06385	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B7470_RS06390	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
B7470_RS06395	COG2068	MobA-Related Protein
B7470_RS06400	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
B7470_RS06405	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
B7470_RS06410	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B7470_RS06415	COG2356	endonuclease I
B7470_RS06420	COG3842	ATPase activity
B7470_RS06425	COG2188	Transcriptional regulator
B7470_RS06430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B7470_RS06440	COG1175	transmembrane transport
B7470_RS06445	COG1653	transport
B7470_RS06450	COG2222	sugar isomerase
B7470_RS06455	COG0322	excinuclease ABC activity
B7470_RS06460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B7470_RS06475	COG0346	lactoylglutathione lyase activity
B7470_RS06480	COG0640	Transcriptional regulator
B7470_RS06485	COG0719	Fe-S assembly protein
B7470_RS06490	COG0822	iron-sulfur transferase activity
B7470_RS06495	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B7470_RS06500	COG0719	Fe-S assembly protein
B7470_RS06505	COG0396	ATPase activity
B7470_RS06525	COG1464	Belongs to the NlpA lipoprotein family
B7470_RS06530	COG2011	ABC-type metal ion transport system permease component
B7470_RS06535	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
B7470_RS06545	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B7470_RS06550	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
B7470_RS06560	COG0509	glycine decarboxylation via glycine cleavage system
B7470_RS06565	COG1393	Belongs to the ArsC family
B7470_RS06570	COG1960	acyl-CoA dehydrogenase activity
B7470_RS06575	COG0183	Belongs to the thiolase family
B7470_RS06580	COG1250	3-hydroxyacyl-CoA dehydrogenase
B7470_RS06580	COG1024	Enoyl-CoA hydratase
B7470_RS06600	COG5577	PFAM Coat F domain
B7470_RS06605	COG1846	Transcriptional regulator
B7470_RS06610	COG0477	Major facilitator Superfamily
B7470_RS06615	COG1942	4-Oxalocrotonate Tautomerase
B7470_RS06620	COG1028	Short-chain dehydrogenase reductase Sdr
B7470_RS06625	COG0583	DNA-binding transcription factor activity
B7470_RS06635	COG1120	ATPase activity
B7470_RS06655	COG1131	(ABC) transporter
B7470_RS06705	COG0783	Belongs to the Dps family
B7470_RS06710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B7470_RS06715	COG0745	RESPONSE REGULATOR receiver
B7470_RS06720	COG2770	Histidine kinase
B7470_RS06720	COG2205	protein histidine kinase activity
B7470_RS06730	COG1309	transcriptional regulator
B7470_RS06735	COG0114	fumarate hydratase activity
B7470_RS06745	COG0697	spore germination
B7470_RS06750	COG0814	amino acid
B7470_RS06760	COG2197	response regulator
B7470_RS06765	COG4585	Histidine kinase
B7470_RS06770	COG4758	membrane
B7470_RS06775	COG3595	metallopeptidase activity
B7470_RS06780	COG1842	Phage shock protein A
B7470_RS06785	COG4758	membrane
B7470_RS06790	COG2814	Major facilitator Superfamily
B7470_RS06795	COG2096	Adenosyltransferase
B7470_RS06800	COG1120	ATPase activity
B7470_RS06805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7470_RS06810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B7470_RS06815	COG1028	Short-chain dehydrogenase reductase Sdr
B7470_RS06820	COG3386	PFAM SMP-30 Gluconolaconase
B7470_RS06825	COG2205	protein histidine kinase activity
B7470_RS06830	COG0745	RESPONSE REGULATOR receiver
B7470_RS06850	COG2140	Oxalate decarboxylase
B7470_RS06860	COG0577	efflux transmembrane transporter activity
B7470_RS06865	COG1136	(ABC) transporter
B7470_RS06870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7470_RS06875	COG1120	ATPase activity
B7470_RS06880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7470_RS06885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7470_RS06890	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B7470_RS06900	COG0531	amino acid
B7470_RS06915	COG1988	membrane-bound metal-dependent
B7470_RS06920	COG1368	sulfuric ester hydrolase activity
B7470_RS06925	COG1910	domain protein
B7470_RS06930	COG0725	ABC transporter, periplasmic molybdate-binding protein
B7470_RS06935	COG4149	molybdate abc transporter
B7470_RS06940	COG0656	L-ascorbic acid biosynthetic process
B7470_RS06950	COG0025	NhaP-type Na H and K H
B7470_RS06955	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B7470_RS06960	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
B7470_RS06965	COG3973	AAA domain
B7470_RS06975	COG2860	membrane
B7470_RS06980	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
B7470_RS06985	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B7470_RS06990	COG2217	Heavy metal translocating P-type atpase
B7470_RS06995	COG2217	Heavy metal translocating P-type atpase
B7470_RS07000	COG2608	mercury ion transmembrane transporter activity
B7470_RS07005	COG1937	Protein conserved in bacteria
B7470_RS07010	COG0673	inositol 2-dehydrogenase activity
B7470_RS07020	COG1289	transmembrane transporter activity
B7470_RS07030	COG2076	Multidrug Resistance protein
B7470_RS07035	COG1309	transcriptional regulator
B7470_RS07040	COG1028	Short-chain dehydrogenase reductase Sdr
B7470_RS07050	COG5444	nuclease activity
B7470_RS07065	COG3409	Peptidoglycan-binding domain 1 protein
B7470_RS07065	COG5632	N-Acetylmuramoyl-L-alanine amidase
B7470_RS07070	COG4824	toxin secretion phage lysis holin
B7470_RS07095	COG1705	Flagellar rod assembly protein muramidase FlgJ
B7470_RS07095	COG3942	CHAP domain
B7470_RS07320	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
B7470_RS07325	COG0557	exoribonuclease II activity
B7470_RS07330	COG1647	Serine aminopeptidase, S33
B7470_RS07335	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B7470_RS07340	COG0596	Alpha beta hydrolase
B7470_RS07345	COG1476	TRANSCRIPTIONal
B7470_RS07350	COG1396	sequence-specific DNA binding
B7470_RS07355	COG1396	sequence-specific DNA binding
B7470_RS07360	COG1733	regulation of RNA biosynthetic process
B7470_RS07365	COG0840	transmembrane signaling receptor activity
B7470_RS07370	COG1174	glycine betaine transport
B7470_RS07375	COG1732	Glycine betaine
B7470_RS07380	COG1174	glycine betaine transport
B7470_RS07385	COG1125	glycine betaine transport
B7470_RS07385	COG0517	IMP dehydrogenase activity
B7470_RS07390	COG1510	regulation of RNA biosynthetic process
B7470_RS07395	COG1174	glycine betaine transport
B7470_RS07400	COG1732	Glycine betaine
B7470_RS07405	COG1174	glycine betaine transport
B7470_RS07410	COG1125	glycine betaine transport
B7470_RS07410	COG0517	IMP dehydrogenase activity
B7470_RS07415	COG1510	regulation of RNA biosynthetic process
B7470_RS07420	COG2095	MarC family integral membrane protein
B7470_RS07430	COG3064	Membrane
B7470_RS07435	COG4640	response to antibiotic
B7470_RS07440	COG0456	acetyltransferase
B7470_RS07445	COG0148	phosphopyruvate hydratase activity
B7470_RS07450	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
B7470_RS07455	COG0149	triose-phosphate isomerase activity
B7470_RS07460	COG0126	phosphoglycerate kinase activity
B7470_RS07465	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B7470_RS07470	COG2390	Transcriptional regulator
B7470_RS07475	COG2814	Major facilitator Superfamily
B7470_RS07480	COG1609	Transcriptional regulator
B7470_RS07485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7470_RS07495	COG0583	DNA-binding transcription factor activity
B7470_RS07500	COG0697	spore germination
B7470_RS07505	COG1113	amino acid transport
B7470_RS07515	COG1556	Lactate utilization protein
B7470_RS07520	COG1139	Iron-sulfur cluster binding protein
B7470_RS07525	COG0247	lactate metabolic process
B7470_RS07530	COG2197	response regulator
B7470_RS07535	COG4585	Histidine kinase
B7470_RS07540	COG0842	Transport permease protein
B7470_RS07545	COG1131	(ABC) transporter
B7470_RS07565	COG0596	Alpha beta hydrolase
B7470_RS07570	COG2208	phosphoserine phosphatase activity
B7470_RS07575	COG3867	Arabinogalactan endo-beta-1,4-galactanase
B7470_RS07580	COG1874	Beta-galactosidase
B7470_RS07585	COG3833	ABC-type maltose transport systems, permease component
B7470_RS07590	COG1175	transmembrane transport
B7470_RS07595	COG2182	Extracellular solute-binding protein
B7470_RS07600	COG1609	Transcriptional regulator
B7470_RS07605	COG2186	Transcriptional regulator
B7470_RS07610	COG1620	l-lactate permease
B7470_RS07615	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
B7470_RS07625	COG5039	Polysaccharide pyruvyl transferase
B7470_RS07630	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B7470_RS07635	COG0110	maltose O-acetyltransferase activity
B7470_RS07640	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B7470_RS07645	COG2244	polysaccharide biosynthetic process
B7470_RS07650	COG1216	Glycosyl transferase, family 2
B7470_RS07655	COG5039	Polysaccharide pyruvyl transferase
B7470_RS07660	COG1216	Glycosyl transferase, family 2
B7470_RS07670	COG0438	transferase activity, transferring glycosyl groups
B7470_RS07675	COG1215	transferase activity, transferring glycosyl groups
B7470_RS07680	COG0438	transferase activity, transferring glycosyl groups
B7470_RS07685	COG1086	Polysaccharide biosynthesis protein
B7470_RS07690	COG0489	protein tyrosine kinase activity
B7470_RS07695	COG3944	biosynthesis protein
B7470_RS07700	COG1396	sequence-specific DNA binding
B7470_RS07705	COG2272	Belongs to the type-B carboxylesterase lipase family
B7470_RS07715	COG3479	Phenolic acid decarboxylase
B7470_RS07730	COG1794	racemase activity, acting on amino acids and derivatives
B7470_RS07740	COG1621	beta-fructofuranosidase activity
B7470_RS07745	COG1621	beta-fructofuranosidase activity
B7470_RS07750	COG0531	amino acid
B7470_RS07755	COG1309	transcriptional regulator
B7470_RS07760	COG2076	Multidrug Resistance protein
B7470_RS07765	COG2076	Multidrug Resistance protein
B7470_RS07785	COG1674	ftsk spoiiie
B7470_RS07805	COG3409	Peptidoglycan-binding domain 1 protein
B7470_RS07805	COG5632	N-Acetylmuramoyl-L-alanine amidase
B7470_RS07805	COG1388	LysM domain
B7470_RS07840	COG1705	Flagellar rod assembly protein muramidase FlgJ
B7470_RS07920	COG0582	viral genome integration into host DNA
B7470_RS08020	COG4974	Belongs to the 'phage' integrase family
B7470_RS08030	COG0740	serine-type endopeptidase activity
B7470_RS08035	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B7470_RS08040	COG0366	Alpha amylase catalytic
B7470_RS08045	COG1554	hydrolase, family 65, central catalytic
B7470_RS08050	COG5521	maltodextrose utilization protein MalA
B7470_RS08055	COG3833	ABC-type maltose transport systems, permease component
B7470_RS08060	COG1175	transmembrane transport
B7470_RS08065	COG2182	Extracellular solute-binding protein
B7470_RS08075	COG1609	Transcriptional regulator
B7470_RS08080	COG1611	Belongs to the LOG family
B7470_RS08090	COG0659	secondary active sulfate transmembrane transporter activity
B7470_RS08095	COG0288	reversible hydration of carbon dioxide
B7470_RS08100	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B7470_RS08105	COG0577	efflux transmembrane transporter activity
B7470_RS08110	COG1136	(ABC) transporter
B7470_RS08115	COG5002	protein histidine kinase activity
B7470_RS08120	COG0745	RESPONSE REGULATOR receiver
B7470_RS08130	COG2162	N-hydroxyarylamine O-acetyltransferase activity
B7470_RS08135	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7470_RS08140	COG1481	regulation of sporulation
B7470_RS08145	COG0391	Required for morphogenesis under gluconeogenic growth conditions
B7470_RS08150	COG1660	Displays ATPase and GTPase activities
B7470_RS08155	COG1051	belongs to the nudix hydrolase family
B7470_RS08160	COG0492	ferredoxin-NADP+ reductase activity
B7470_RS08165	COG3883	PFAM NLP P60 protein
B7470_RS08165	COG0791	NLP P60 protein
B7470_RS08170	COG0457	Tetratricopeptide repeat
B7470_RS08175	COG1132	(ABC) transporter
B7470_RS08195	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
B7470_RS08195	COG0140	phosphoribosyl-ATP diphosphatase activity
B7470_RS08200	COG0107	imidazoleglycerol-phosphate synthase activity
B7470_RS08205	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
B7470_RS08210	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
B7470_RS08215	COG0131	Imidazoleglycerol-phosphate dehydratase
B7470_RS08220	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
B7470_RS08225	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
B7470_RS08230	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
B7470_RS08235	COG4990	cell redox homeostasis
B7470_RS08240	COG5297	Belongs to the glycosyl hydrolase family 6
B7470_RS08255	COG0546	phosphoglycolate phosphatase activity
B7470_RS08260	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
B7470_RS08265	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
B7470_RS08270	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
B7470_RS08275	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
B7470_RS08280	COG0363	glucosamine-6-phosphate deaminase activity
B7470_RS08285	COG2188	Transcriptional regulator
B7470_RS08290	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B7470_RS08305	COG1950	PFAM Membrane protein of
B7470_RS08310	COG1983	PspC domain protein
B7470_RS08315	COG3595	metallopeptidase activity
B7470_RS08330	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B7470_RS08335	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B7470_RS08340	COG0556	nucleotide-excision repair
B7470_RS08345	COG4897	Protein conserved in bacteria
B7470_RS08350	COG3848	Pyruvate phosphate dikinase
B7470_RS08350	COG0574	Belongs to the PEP-utilizing enzyme family
B7470_RS08355	COG1309	transcriptional regulator
B7470_RS08360	COG2814	Major facilitator Superfamily
B7470_RS08365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B7470_RS08375	COG0793	Belongs to the peptidase S41A family
B7470_RS08375	COG3409	Peptidoglycan-binding domain 1 protein
B7470_RS08380	COG2177	Part of the ABC transporter FtsEX involved in
B7470_RS08385	COG2884	Cell division ATP-binding protein ftsE
B7470_RS08390	COG2010	Cytochrome c
B7470_RS08395	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B7470_RS08405	COG0653	protein targeting
B7470_RS08410	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
B7470_RS08425	COG1516	flagellar protein fliS
B7470_RS08430	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
B7470_RS08435	COG1334	flagellar protein FlaG
B7470_RS08440	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B7470_RS08445	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
B7470_RS08450	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
B7470_RS08460	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B7470_RS08465	COG4786	Flagellar basal body rod
B7470_RS08465	COG1256	bacterial-type flagellum assembly
B7470_RS08470	COG3418	PFAM FlgN family protein
B7470_RS08475	COG2747	anti-sigma28 factor FlgM
B7470_RS08485	COG1040	competence protein
B7470_RS08495	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
B7470_RS08500	COG1307	EDD domain protein, DegV family
B7470_RS08505	COG2197	response regulator
B7470_RS08510	COG4585	Histidine kinase
B7470_RS08515	COG1739	Uncharacterized protein family UPF0029
B7470_RS08520	COG1316	TRANSCRIPTIONal
B7470_RS08555	COG1131	(ABC) transporter
B7470_RS08565	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B7470_RS08570	COG0438	transferase activity, transferring glycosyl groups
B7470_RS08575	COG1215	transferase activity, transferring glycosyl groups
B7470_RS08580	COG3206	protein involved in exopolysaccharide biosynthesis
B7470_RS08585	COG3307	-O-antigen
B7470_RS08595	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
B7470_RS08600	COG0438	transferase activity, transferring glycosyl groups
B7470_RS08600	COG0297	glycogen (starch) synthase activity
B7470_RS08605	COG2244	polysaccharide biosynthetic process
B7470_RS08620	COG2247	cell wall binding repeat
B7470_RS08620	COG0860	N-Acetylmuramoyl-L-alanine amidase
B7470_RS08625	COG2385	sporulation resulting in formation of a cellular spore
B7470_RS08625	COG2247	cell wall binding repeat
B7470_RS08655	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
B7470_RS08660	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B7470_RS08670	COG1134	teichoic acid transport
B7470_RS08675	COG1682	transport, permease protein
B7470_RS08690	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B7470_RS08690	COG0463	Glycosyl transferase, family 2
B7470_RS08695	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B7470_RS08700	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
B7470_RS08705	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
B7470_RS08710	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B7470_RS08715	COG4193	domain, Protein
B7470_RS08720	COG1482	cell wall glycoprotein biosynthetic process
B7470_RS08725	COG0697	spore germination
B7470_RS08730	COG0814	amino acid
B7470_RS08745	COG1316	TRANSCRIPTIONal
B7470_RS08750	COG0561	phosphatase activity
B7470_RS08755	COG0791	NLP P60 protein
B7470_RS08765	COG2843	Capsule synthesis protein
B7470_RS08775	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
B7470_RS08785	COG1609	Transcriptional regulator
B7470_RS08790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B7470_RS08795	COG1869	D-ribose catabolic process
B7470_RS08800	COG1129	ABC transporter
B7470_RS08805	COG1172	Belongs to the binding-protein-dependent transport system permease family
B7470_RS08810	COG1879	ABC-type sugar transport system periplasmic component
B7470_RS08815	COG3103	Sh3 type 3 domain protein
B7470_RS08825	COG2249	NAD(P)H dehydrogenase (quinone) activity
B7470_RS08830	COG3527	Alpha-acetolactate decarboxylase
B7470_RS08835	COG0028	Belongs to the TPP enzyme family
B7470_RS08840	COG0583	DNA-binding transcription factor activity
B7470_RS08845	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B7470_RS08860	COG5337	Spore coat protein CotH
B7470_RS08870	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B7470_RS08880	COG0405	Gamma-glutamyltransferase
B7470_RS08885	COG1522	sequence-specific DNA binding
B7470_RS08890	COG2059	Chromate
B7470_RS08895	COG2059	Chromate
B7470_RS08905	COG0655	NAD(P)H dehydrogenase (quinone) activity
B7470_RS08910	COG0583	DNA-binding transcription factor activity
B7470_RS08940	COG5444	nuclease activity
B7470_RS08960	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
B7470_RS08965	COG4464	protein tyrosine phosphatase activity
B7470_RS08970	COG0489	protein tyrosine kinase activity
B7470_RS08975	COG3944	biosynthesis protein
B7470_RS08985	COG4715	Zinc finger, swim domain protein
B7470_RS08990	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B7470_RS09000	COG0561	phosphatase activity
B7470_RS09005	COG1349	DNA-binding transcription factor activity
B7470_RS09010	COG0629	single-stranded DNA binding
B7470_RS09025	COG3764	Sortase (surface protein transpeptidase)
B7470_RS09030	COG0745	RESPONSE REGULATOR receiver
B7470_RS09030	COG2972	Histidine kinase
B7470_RS09035	COG1970	mechanosensitive ion channel activity
B7470_RS09040	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B7470_RS09045	COG0457	Tetratricopeptide repeat
B7470_RS09050	COG4786	Flagellar basal body rod
B7470_RS09055	COG4786	Flagellar basal body rod
B7470_RS09060	COG1077	Cell shape determining protein MreB Mrl
B7470_RS09065	COG1609	Transcriptional regulator
B7470_RS09075	COG1846	Transcriptional regulator
B7470_RS09080	COG2814	Major facilitator Superfamily
B7470_RS09085	COG3420	alginic acid biosynthetic process
B7470_RS09090	COG1953	Uracil, thiamine, allantoin
B7470_RS09095	COG0477	Major facilitator Superfamily
B7470_RS09100	COG1335	isochorismatase
B7470_RS09110	COG0004	ammonium transporteR
B7470_RS09115	COG0347	Belongs to the P(II) protein family
B7470_RS09120	COG0671	phosphoesterase, PA-phosphatase related
B7470_RS09130	COG0739	heme binding
B7470_RS09135	COG1247	-acetyltransferase
B7470_RS09145	COG2089	acid synthase
B7470_RS09155	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B7470_RS09160	COG0789	Transcriptional regulator
B7470_RS09170	COG2910	NAD(P)H-binding
B7470_RS09175	COG1959	2 iron, 2 sulfur cluster binding
B7470_RS09180	COG0804	urea catabolic process
B7470_RS09185	COG0832	Belongs to the urease beta subunit family
B7470_RS09190	COG0831	urea catabolic process
B7470_RS09205	COG3237	CsbD-like
B7470_RS09210	COG1994	Peptidase M50
B7470_RS09215	COG0457	Tetratricopeptide repeat
B7470_RS09225	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B7470_RS09230	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
B7470_RS09240	COG2304	oxidoreductase activity
B7470_RS09250	COG2304	oxidoreductase activity
B7470_RS09255	COG2385	sporulation resulting in formation of a cellular spore
B7470_RS09260	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B7470_RS09270	COG4836	Membrane
B7470_RS09280	COG0355	proton-transporting ATP synthase activity, rotational mechanism
B7470_RS09285	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
B7470_RS09290	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
B7470_RS09295	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
B7470_RS09300	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B7470_RS09305	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
B7470_RS09315	COG0356	it plays a direct role in the translocation of protons across the membrane
B7470_RS09325	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
B7470_RS09330	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B7470_RS09335	COG4475	Protein of unknown function (DUF436)
B7470_RS09340	COG0698	ribose 5-phosphate isomerase
B7470_RS09345	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B7470_RS09350	COG1971	Probably functions as a manganese efflux pump
B7470_RS09355	COG0009	L-threonylcarbamoyladenylate synthase
B7470_RS09360	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
B7470_RS09380	COG2890	protein-(glutamine-N5) methyltransferase activity
B7470_RS09385	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
B7470_RS09390	COG0346	lactoylglutathione lyase activity
B7470_RS09395	COG0789	Transcriptional regulator
B7470_RS09400	COG0679	Auxin Efflux Carrier
B7470_RS09405	COG0281	malic enzyme
B7470_RS09410	COG1435	thymidine kinase activity
B7470_RS09420	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
B7470_RS09425	COG1494	fructose-1,6-bisphosphatase
B7470_RS09430	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B7470_RS09435	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B7470_RS09440	COG0191	fructose-bisphosphate aldolase activity
B7470_RS09445	COG2204	response regulator
B7470_RS09450	COG4821	SIS domain
B7470_RS09455	COG0504	CTP synthase activity
B7470_RS09460	COG3343	RNA polymerase activity
B7470_RS09465	COG1960	acyl-CoA dehydrogenase activity
B7470_RS09470	COG0247	lactate metabolic process
B7470_RS09470	COG2181	nitrate reductase activity
B7470_RS09475	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B7470_RS09480	COG4294	response to UV
B7470_RS09490	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
B7470_RS09500	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B7470_RS09510	COG2181	nitrate reductase activity
B7470_RS09515	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
B7470_RS09520	COG1140	nitrate reductase beta subunit
B7470_RS09525	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
B7470_RS09530	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B7470_RS09540	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B7470_RS09545	COG2223	nitrite transmembrane transporter activity
B7470_RS09550	COG0018	arginyl-trna synthetase
B7470_RS09555	COG4506	Protein conserved in bacteria
B7470_RS09570	COG0535	radical SAM domain protein
B7470_RS09580	COG1131	(ABC) transporter
B7470_RS09585	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
B7470_RS09590	COG0612	Peptidase, M16
B7470_RS09595	COG0612	Peptidase, M16
B7470_RS09605	COG3391	amine dehydrogenase activity
B7470_RS09610	COG3391	amine dehydrogenase activity
B7470_RS09620	COG0457	Tetratricopeptide repeat
B7470_RS09630	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B7470_RS09635	COG0010	Belongs to the arginase family
B7470_RS09640	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
B7470_RS09645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B7470_RS09660	COG1994	Peptidase M50
B7470_RS09665	COG1942	4-Oxalocrotonate Tautomerase
B7470_RS09670	COG1846	Transcriptional regulator
B7470_RS09675	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
B7470_RS09680	COG0477	Major facilitator Superfamily
B7470_RS09685	COG1959	2 iron, 2 sulfur cluster binding
B7470_RS09690	COG3465	dGTPase activity
B7470_RS09695	COG1078	dGTPase activity
B7470_RS09700	COG4844	belongs to the
B7470_RS09710	COG0697	spore germination
B7470_RS09715	COG0095	Lipoate-protein ligase
B7470_RS09720	COG0583	DNA-binding transcription factor activity
B7470_RS09725	COG0280	phosphate acetyltransferase
B7470_RS09735	COG1028	Short-chain dehydrogenase reductase Sdr
B7470_RS09740	COG0436	Aminotransferase
B7470_RS09745	COG2814	Major facilitator Superfamily
B7470_RS09750	COG0151	Belongs to the GarS family
B7470_RS09755	COG1028	Short-chain dehydrogenase reductase Sdr
B7470_RS09760	COG1917	Cupin 2, conserved barrel domain protein
B7470_RS09765	COG0077	Prephenate dehydratase
B7470_RS09770	COG2814	Major facilitator Superfamily
B7470_RS09775	COG0833	amino acid
B7470_RS09780	COG4187	Peptidase family M20/M25/M40
B7470_RS09785	COG1012	belongs to the aldehyde dehydrogenase family
B7470_RS09790	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B7470_RS09800	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
B7470_RS09805	COG1091	dTDP-4-dehydrorhamnose reductase activity
B7470_RS09810	COG1088	dTDP-glucose 4,6-dehydratase activity
B7470_RS09815	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
B7470_RS09820	COG3980	spore coat polysaccharide biosynthesis protein
B7470_RS09825	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
B7470_RS09830	COG2089	acid synthase
B7470_RS09835	COG0456	acetyltransferase
B7470_RS09840	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B7470_RS09845	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B7470_RS09850	COG0463	Glycosyl transferase, family 2
B7470_RS09865	COG2363	Small membrane protein
B7470_RS09870	COG2233	PERMEase
B7470_RS09880	COG1012	belongs to the aldehyde dehydrogenase family
B7470_RS09885	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
B7470_RS09890	COG1216	Glycosyl transferase, family 2
B7470_RS09895	COG0351	phosphomethylpyrimidine kinase
B7470_RS09905	COG1621	beta-fructofuranosidase activity
B7470_RS09910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B7470_RS09910	COG1263	PTS System
B7470_RS09915	COG2116	formate transmembrane transporter activity
B7470_RS09930	COG1404	Belongs to the peptidase S8 family
B7470_RS09935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7470_RS09940	COG0778	Nitroreductase
B7470_RS09945	COG0772	Belongs to the SEDS family
B7470_RS09960	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
B7470_RS09965	COG1845	cytochrome c oxidase, subunit III
B7470_RS09970	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B7470_RS09975	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
B7470_RS09980	COG2261	transglycosylase associated protein
B7470_RS09985	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
B7470_RS09990	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
B7470_RS09995	COG2246	polysaccharide biosynthetic process
B7470_RS10000	COG1309	transcriptional regulator
B7470_RS10010	COG3162	membrane
B7470_RS10015	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B7470_RS10020	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
B7470_RS10025	COG2837	iron assimilation
B7470_RS10030	COG2822	iron ion transport
B7470_RS10035	COG0672	)-iron permease
B7470_RS10040	COG0352	thiamine-phosphate diphosphorylase activity
B7470_RS10045	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
B7470_RS10050	COG0583	DNA-binding transcription factor activity
B7470_RS10055	COG1380	Effector of murein hydrolase LrgA
B7470_RS10060	COG1346	cytolysis
B7470_RS10065	COG2814	Major facilitator Superfamily
B7470_RS10070	COG4895	conserved protein (DUF2196)
B7470_RS10075	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
B7470_RS10080	COG0346	lactoylglutathione lyase activity
B7470_RS10090	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B7470_RS10100	COG1263	PTS System
B7470_RS10100	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B7470_RS10105	COG3711	transcriptional antiterminator
B7470_RS10110	COG1442	glycosyl transferase family 8
B7470_RS10115	COG5522	Integral membrane protein (intg_mem_TP0381)
B7470_RS10120	COG1846	Transcriptional regulator
B7470_RS10125	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
B7470_RS10130	COG2234	aminopeptidase activity
B7470_RS10135	COG2357	RelA SpoT domain protein
B7470_RS10150	COG1575	Belongs to the MenA family. Type 1 subfamily
B7470_RS10165	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7470_RS10170	COG1696	Membrane protein involved in D-alanine export
B7470_RS10175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B7470_RS10180	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
B7470_RS10190	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B7470_RS10195	COG1486	melibiose metabolic process
B7470_RS10200	COG1447	Phosphotransferase system cellobiose-specific component IIA
B7470_RS10205	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B7470_RS10210	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B7470_RS10215	COG3711	transcriptional antiterminator
B7470_RS10215	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7470_RS10225	COG2094	Belongs to the DNA glycosylase MPG family
B7470_RS10230	COG0753	catalase activity
B7470_RS10235	COG2814	Major facilitator Superfamily
B7470_RS10240	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
B7470_RS10245	COG1131	(ABC) transporter
B7470_RS10265	COG1595	DNA-templated transcription, initiation
B7470_RS10270	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
B7470_RS10275	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
B7470_RS10280	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
B7470_RS10285	COG4988	ABC transporter
B7470_RS10290	COG1294	oxidase, subunit
B7470_RS10295	COG1271	oxidase subunit
B7470_RS10300	COG3493	citrate carrier protein
B7470_RS10305	COG0501	Belongs to the peptidase M48B family
B7470_RS10315	COG0726	polysaccharide deacetylase
B7470_RS10320	COG3842	ATPase activity
B7470_RS10325	COG2508	Transcriptional regulator
B7470_RS10330	COG1012	belongs to the aldehyde dehydrogenase family
B7470_RS10335	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B7470_RS10345	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B7470_RS10355	COG4585	Histidine kinase
B7470_RS10360	COG2197	response regulator
B7470_RS10365	COG2195	Cleaves the N-terminal amino acid of tripeptides
B7470_RS10375	COG4894	glucomannan catabolic process
B7470_RS10380	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
B7470_RS10385	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
B7470_RS10390	COG1028	Short-chain dehydrogenase reductase Sdr
B7470_RS10395	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B7470_RS10400	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
B7470_RS10405	COG2610	gluconate transmembrane transporter activity
B7470_RS10410	COG0500	methyltransferase
B7470_RS10415	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B7470_RS10430	COG0753	catalase activity
B7470_RS10430	COG0693	protein deglycase activity
B7470_RS10435	COG2851	Citrate transporter
B7470_RS10440	COG2273	Hydrolase Family 16
B7470_RS10445	COG3711	transcriptional antiterminator
B7470_RS10460	COG2270	Major facilitator Superfamily
B7470_RS10465	COG0513	Belongs to the DEAD box helicase family
B7470_RS10470	COG3401	FG-GAP repeat protein
B7470_RS10470	COG2755	lipolytic protein G-D-S-L family
B7470_RS10600	COG0589	response to stress
B7470_RS10610	COG1263	PTS System
B7470_RS10610	COG2190	(PTS) system
B7470_RS10610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B7470_RS10630	COG5444	nuclease activity
B7470_RS10650	COG0494	nUDIX hydrolase
B7470_RS10655	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
B7470_RS10660	COG3507	Belongs to the glycosyl hydrolase 43 family
B7470_RS10675	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
B7470_RS10680	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B7470_RS10685	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
B7470_RS10690	COG2390	Transcriptional regulator
B7470_RS10700	COG3192	ethanolamine utilization protein
B7470_RS10705	COG2079	MmgE PrpD family protein
B7470_RS10710	COG1473	amidohydrolase
B7470_RS10715	COG1126	abc transporter atp-binding protein
B7470_RS10720	COG0765	amino acid transport
B7470_RS10725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7470_RS10730	COG0456	acetyltransferase
B7470_RS10735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7470_RS10740	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
B7470_RS10745	COG0561	phosphatase activity
B7470_RS10775	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B7470_RS10780	COG5294	Protein conserved in bacteria
B7470_RS10795	COG2205	protein histidine kinase activity
B7470_RS10800	COG0745	RESPONSE REGULATOR receiver
B7470_RS10805	COG0191	fructose-bisphosphate aldolase activity
B7470_RS10810	COG1082	Xylose isomerase domain protein TIM barrel
B7470_RS10815	COG1082	Xylose isomerase domain protein TIM barrel
B7470_RS10820	COG0673	inositol 2-dehydrogenase activity
B7470_RS10825	COG2814	Major facilitator Superfamily
B7470_RS10830	COG1082	Xylose isomerase domain protein TIM barrel
B7470_RS10835	COG3962	Belongs to the TPP enzyme family
B7470_RS10840	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B7470_RS10860	COG1349	DNA-binding transcription factor activity
B7470_RS10865	COG0667	Aldo Keto reductase
B7470_RS10895	COG0326	Molecular chaperone. Has ATPase activity
B7470_RS10955	COG1917	Cupin 2, conserved barrel domain protein
B7470_RS10960	COG1309	transcriptional regulator
B7470_RS10965	COG1028	Short-chain dehydrogenase reductase Sdr
B7470_RS10970	COG1846	Transcriptional regulator
B7470_RS10975	COG1380	Effector of murein hydrolase LrgA
B7470_RS10980	COG1346	cytolysis
B7470_RS10985	COG5039	Polysaccharide pyruvyl transferase
B7470_RS10990	COG1929	Belongs to the glycerate kinase type-1 family
B7470_RS10995	COG1802	Transcriptional regulator
B7470_RS11000	COG1070	Carbohydrate kinase
B7470_RS11005	COG2610	gluconate transmembrane transporter activity
B7470_RS11010	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
B7470_RS11015	COG0450	alkyl hydroperoxide reductase
B7470_RS11020	COG3634	alkyl hydroperoxide reductase activity
B7470_RS11025	COG2723	6-phospho-beta-galactosidase activity
B7470_RS11040	COG2188	Transcriptional regulator
B7470_RS11050	COG1131	(ABC) transporter
B7470_RS11055	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
B7470_RS11070	COG0071	Belongs to the small heat shock protein (HSP20) family
B7470_RS11105	COG0210	DNA helicase
B7470_RS11135	COG2963	transposase activity
B7470_RS11170	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
B7470_RS11185	COG1063	alcohol dehydrogenase
B7470_RS11205	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
B7470_RS11210	COG0456	acetyltransferase
B7470_RS11215	COG0457	Tetratricopeptide repeat
B7470_RS11225	COG0010	Belongs to the arginase family
B7470_RS11230	COG0833	amino acid
B7470_RS11235	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B7470_RS11255	COG5658	integral membrane protein
B7470_RS11260	COG0640	Transcriptional regulator
B7470_RS11265	COG3829	transcription factor binding
B7470_RS11275	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B7470_RS11280	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
B7470_RS11285	COG4853	Protein conserved in bacteria
B7470_RS11290	COG4863	YycH protein
B7470_RS11295	COG5002	protein histidine kinase activity
B7470_RS11300	COG0745	RESPONSE REGULATOR receiver
B7470_RS11330	COG0346	lactoylglutathione lyase activity
B7470_RS11335	COG0305	Participates in initiation and elongation during chromosome replication
B7470_RS11350	COG3093	addiction module antidote protein HigA
B7470_RS11355	COG2807	transmembrane transport
B7470_RS11360	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
B7470_RS11365	COG0359	binds to the 23S rRNA
B7470_RS11370	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
B7470_RS11375	COG4241	membrane
B7470_RS11390	COG1733	regulation of RNA biosynthetic process
B7470_RS11395	COG1227	inorganic diphosphatase activity
B7470_RS11410	COG2271	Major facilitator Superfamily
B7470_RS11415	COG4978	Transcriptional regulator
B7470_RS11415	COG0789	Transcriptional regulator
B7470_RS11425	COG4319	ketosteroid isomerase
B7470_RS11430	COG1357	PFAM Pentapeptide repeats (8 copies)
B7470_RS11445	COG1846	Transcriptional regulator
B7470_RS11450	COG2153	protein acetylation
B7470_RS11455	COG2364	Membrane
B7470_RS11460	COG0456	acetyltransferase
B7470_RS11465	COG2315	Protein conserved in bacteria
B7470_RS11470	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
B7470_RS11475	COG1331	Highly conserved protein containing a thioredoxin domain
B7470_RS11480	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
B7470_RS11485	COG1331	Highly conserved protein containing a thioredoxin domain
B7470_RS11490	COG1266	CAAX protease self-immunity
B7470_RS11495	COG0477	Major facilitator Superfamily
B7470_RS11495	COG2814	Major facilitator Superfamily
B7470_RS11500	COG0346	lactoylglutathione lyase activity
B7470_RS11505	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B7470_RS11510	COG0542	response to heat
B7470_RS11525	COG0708	Exodeoxyribonuclease III
B7470_RS11530	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
B7470_RS11535	COG0629	single-stranded DNA binding
B7470_RS11540	COG0360	Binds together with S18 to 16S ribosomal RNA
B7470_RS11545	COG0012	GTP binding
B7470_RS11550	COG0243	molybdopterin cofactor binding
B7470_RS11555	COG4481	Protein conserved in bacteria
B7470_RS11560	COG3949	Membrane
B7470_RS11570	COG1475	DNA binding
B7470_RS11575	COG1192	Involved in chromosome partitioning
B7470_RS11585	COG1475	DNA binding
B7470_RS11590	COG0357	Ribosomal RNA small subunit methyltransferase G
B7470_RS11595	COG0445	tRNA wobble uridine modification
B7470_RS11600	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
B7470_RS11605	COG1847	R3H domain protein
B7470_RS11610	COG0706	membrane insertase activity
B7470_RS11615	COG0594	ribonuclease P activity
B7470_RS11625	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
B7470_RS11630	COG0592	DNA-directed DNA polymerase activity
B7470_RS11635	COG2501	S4 domain
B7470_RS11640	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
B7470_RS11650	COG0187	DNA topoisomerase II activity
B7470_RS11655	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B7470_RS11690	COG0516	GMP reductase activity
B7470_RS11690	COG0517	IMP dehydrogenase activity
B7470_RS11695	COG1686	Belongs to the peptidase S11 family
B7470_RS11700	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
B7470_RS11705	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
B7470_RS11710	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
B7470_RS11720	COG1428	Deoxynucleoside kinase
B7470_RS11725	COG1428	Deoxynucleoside kinase
B7470_RS11730	COG3858	chitin binding
B7470_RS11730	COG1388	LysM domain
B7470_RS11735	COG1335	isochorismatase
B7470_RS11740	COG0590	tRNA wobble adenosine to inosine editing
B7470_RS11750	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
B7470_RS11755	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
B7470_RS11760	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
B7470_RS11805	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
B7470_RS11810	COG3853	Toxic anion resistance protein (TelA)
B7470_RS11815	COG1982	Orn Lys Arg decarboxylase major
B7470_RS11820	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
B7470_RS11825	COG3870	Protein conserved in bacteria
B7470_RS11830	COG1728	Protein conserved in bacteria
B7470_RS11835	COG0470	DNA polymerase III
B7470_RS11840	COG1774	PSP1 C-terminal conserved region
B7470_RS11845	COG4467	Involved in initiation control of chromosome replication
B7470_RS11850	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
B7470_RS11855	COG2827	Endonuclease containing a URI domain
B7470_RS11860	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
B7470_RS11865	COG2002	toxin-antitoxin pair type II binding
B7470_RS11870	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B7470_RS11870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B7470_RS11875	COG0084	hydrolase, TatD family'
B7470_RS11880	COG3584	3D domain protein
B7470_RS11880	COG3583	domain protein
B7470_RS11885	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
B7470_RS11890	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
B7470_RS11900	COG4466	Protein conserved in bacteria
B7470_RS11910	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
B7470_RS11915	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B7470_RS11920	COG0251	oxidation-reduction process
B7470_RS11925	COG2088	sporulation resulting in formation of a cellular spore
B7470_RS11930	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
B7470_RS11935	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B7470_RS11940	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
B7470_RS11945	COG0193	aminoacyl-tRNA hydrolase activity
B7470_RS11955	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
B7470_RS11960	COG2002	toxin-antitoxin pair type II binding
B7470_RS11965	COG2244	polysaccharide biosynthetic process
B7470_RS11970	COG3956	TIGRFAM MazG family protein
B7470_RS11975	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
B7470_RS11990	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
B7470_RS11995	COG1098	S1 RNA binding domain
B7470_RS12010	COG2208	phosphoserine phosphatase activity
B7470_RS12015	COG2304	oxidoreductase activity
B7470_RS12025	COG0037	tRNA processing
B7470_RS12035	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B7470_RS12040	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
B7470_RS12045	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
B7470_RS12050	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B7470_RS12055	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B7470_RS12060	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B7470_RS12065	COG0512	Glutamine amidotransferase of anthranilate synthase
B7470_RS12070	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B7470_RS12075	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
B7470_RS12080	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
B7470_RS12085	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
B7470_RS12090	COG1396	sequence-specific DNA binding
B7470_RS12095	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B7470_RS12100	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
B7470_RS12180	COG4463	regulation of RNA biosynthetic process
B7470_RS12185	COG3880	PFAM UvrB UvrC protein
B7470_RS12190	COG3869	Catalyzes the specific phosphorylation of arginine residues in
B7470_RS12195	COG0542	response to heat
B7470_RS12200	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
B7470_RS12205	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
B7470_RS12210	COG4956	integral membrane protein (PIN domain superfamily)
B7470_RS12215	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
B7470_RS12220	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
B7470_RS12225	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B7470_RS12235	COG1045	serine acetyltransferase
B7470_RS12240	COG0215	cysteine-tRNA ligase activity
B7470_RS12245	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
B7470_RS12250	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B7470_RS12255	COG3688	RNA-binding protein containing a PIN domain
B7470_RS12260	COG1595	DNA-templated transcription, initiation
B7470_RS12270	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B7470_RS12275	COG0250	Participates in transcription elongation, termination and antitermination
B7470_RS12285	COG0081	regulation of translation
B7470_RS12290	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
B7470_RS12300	COG2813	Specifically methylates the guanine in position
B7470_RS12305	COG0085	RNA polymerase activity
B7470_RS12310	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
B7470_RS12315	COG1358	cellular component organization or biogenesis
B7470_RS12320	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
B7470_RS12325	COG0049	tRNA binding
B7470_RS12330	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
B7470_RS12335	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B7470_RS12340	COG0596	Alpha beta hydrolase
B7470_RS12350	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
B7470_RS12355	COG0088	Forms part of the polypeptide exit tunnel
B7470_RS12365	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
B7470_RS12385	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
B7470_RS12395	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
B7470_RS12400	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
B7470_RS12410	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
B7470_RS12420	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
B7470_RS12425	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
B7470_RS12430	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
B7470_RS12435	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
B7470_RS12445	COG0200	Binds to the 23S rRNA
B7470_RS12450	COG0201	protein transport
B7470_RS12455	COG0563	adenylate kinase activity
B7470_RS12460	COG0024	Methionine aminopeptidase
B7470_RS12465	COG2163	COG2163 Ribosomal protein L14E L6E L27E
B7470_RS12475	COG0257	Belongs to the bacterial ribosomal protein bL36 family
B7470_RS12480	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
B7470_RS12485	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
B7470_RS12490	COG0202	RNA polymerase activity
B7470_RS12495	COG0203	ribosomal protein L17
B7470_RS12500	COG1122	ATPase activity
B7470_RS12505	COG1122	ATPase activity
B7470_RS12510	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
B7470_RS12515	COG0101	tRNA pseudouridine synthase activity
B7470_RS12520	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
B7470_RS12525	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B7470_RS12535	COG2226	methyltransferase
B7470_RS12545	COG0860	N-Acetylmuramoyl-L-alanine amidase
B7470_RS12550	COG0489	protein tyrosine kinase activity
B7470_RS12560	COG2194	sulfuric ester hydrolase activity
B7470_RS12565	COG0726	polysaccharide deacetylase
B7470_RS12645	COG0659	secondary active sulfate transmembrane transporter activity
B7470_RS12650	COG0385	Bile acid
B7470_RS12655	COG2819	hydrolase of the alpha beta superfamily
B7470_RS12660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7470_RS12665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7470_RS12670	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B7470_RS12675	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B7470_RS12675	COG2207	Transcriptional regulator
B7470_RS12680	COG3876	Protein conserved in bacteria
B7470_RS12685	COG1472	Belongs to the glycosyl hydrolase 3 family
B7470_RS12690	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B7470_RS12695	COG1263	PTS System
B7470_RS12695	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B7470_RS12700	COG1737	Transcriptional regulator
B7470_RS12705	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
B7470_RS12710	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B7470_RS12715	COG1683	Conserved Protein
B7470_RS12745	COG1595	DNA-templated transcription, initiation
B7470_RS12750	COG5662	AntiSigma factor
B7470_RS12755	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
B7470_RS12760	COG4856	YbbR-like protein
B7470_RS12765	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B7470_RS12775	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B7470_RS12785	COG2169	Transcriptional regulator
B7470_RS12790	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B7470_RS12795	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B7470_RS12800	COG3002	Belongs to the UPF0753 family
B7470_RS12805	COG0288	reversible hydration of carbon dioxide
B7470_RS12815	COG5609	conserved protein (DUF2294)
B7470_RS12825	COG0642	Histidine kinase
B7470_RS12835	COG0515	serine threonine protein kinase
B7470_RS12850	COG1113	amino acid transport
B7470_RS12865	COG2602	Beta-lactamase
B7470_RS12870	COG2124	cytochrome p450
B7470_RS12880	COG0531	amino acid
B7470_RS12885	COG0584	glycerophosphoryl diester phosphodiesterase
B7470_RS12890	COG2271	Major facilitator Superfamily
B7470_RS12905	COG0456	acetyltransferase
B7470_RS12905	COG1846	Transcriptional regulator
B7470_RS12925	COG3409	Peptidoglycan-binding domain 1 protein
B7470_RS12930	COG0697	spore germination
B7470_RS12935	COG1917	Cupin 2, conserved barrel domain protein
B7470_RS12935	COG2207	Transcriptional regulator
B7470_RS12960	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
B7470_RS12965	COG3591	Belongs to the peptidase S1B family
B7470_RS12975	COG0596	Alpha beta hydrolase
B7470_RS12980	COG1183	phosphatidylcholine synthase activity
B7470_RS12985	COG0586	Pfam SNARE associated Golgi protein
B7470_RS12990	COG0688	phosphatidylethanolamine metabolic process
B7470_RS13000	COG2312	Erythromycin esterase
B7470_RS13005	COG2207	Transcriptional regulator
B7470_RS13015	COG1301	dicarboxylic acid transport
B7470_RS13020	COG2190	(PTS) system
B7470_RS13020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B7470_RS13020	COG1263	PTS System
B7470_RS13025	COG0363	glucosamine-6-phosphate deaminase activity
B7470_RS13030	COG2188	Transcriptional regulator
B7470_RS13040	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B7470_RS13045	COG0833	amino acid
B7470_RS13050	COG2040	homocysteine
B7470_RS13065	COG2066	Belongs to the glutaminase family
B7470_RS13070	COG4191	Histidine kinase
B7470_RS13075	COG0784	Response regulator, receiver
B7470_RS13085	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B7470_RS13090	COG1012	belongs to the aldehyde dehydrogenase family
B7470_RS13095	COG2271	Major facilitator Superfamily
B7470_RS13100	COG4948	Mandelate Racemase Muconate Lactonizing
B7470_RS13105	COG2186	Transcriptional regulator
B7470_RS13110	COG2721	sulfolactate sulfo-lyase activity
B7470_RS13115	COG3173	Aminoglycoside phosphotransferase
B7470_RS13125	COG0697	spore germination
B7470_RS13130	COG0745	RESPONSE REGULATOR receiver
B7470_RS13135	COG2205	protein histidine kinase activity
B7470_RS13140	COG1131	(ABC) transporter
B7470_RS13155	COG3773	Cell wall hydrolase
B7470_RS13160	COG2304	oxidoreductase activity
B7470_RS13170	COG3540	Alkaline phosphatase
B7470_RS13175	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B7470_RS13180	COG0805	protein transport
B7470_RS13185	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
B7470_RS13190	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B7470_RS13195	COG0477	Major facilitator Superfamily
B7470_RS13200	COG1309	transcriptional regulator
B7470_RS13205	COG0252	asparaginase activity
B7470_RS13210	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
B7470_RS13215	COG1714	RDD family
B7470_RS13220	COG3012	SEC-C Motif Domain Protein
B7470_RS13220	COG1405	negative regulation of cell septum assembly
B7470_RS13230	COG3279	Response regulator of the LytR AlgR family
B7470_RS13240	COG1668	transmembrane transport
B7470_RS13245	COG0667	Aldo Keto reductase
B7470_RS13255	COG1595	DNA-templated transcription, initiation
B7470_RS13265	COG1595	DNA-templated transcription, initiation
B7470_RS13270	COG1876	peptidase activity
B7470_RS13280	COG1028	Short-chain dehydrogenase reductase Sdr
B7470_RS13285	COG0366	Alpha amylase catalytic
B7470_RS13290	COG0803	Belongs to the bacterial solute-binding protein 9 family
B7470_RS13295	COG1121	(ABC) transporter
B7470_RS13300	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B7470_RS13310	COG2310	stress, protein
B7470_RS13315	COG2310	stress, protein
B7470_RS13320	COG2310	stress, protein
B7470_RS13325	COG0861	Integral membrane protein TerC family
B7470_RS13335	COG3853	Toxic anion resistance protein (TelA)
B7470_RS13345	COG0477	Major facilitator Superfamily
B7470_RS13350	COG2814	Major facilitator Superfamily
B7470_RS13355	COG0640	Transcriptional regulator
B7470_RS13360	COG4175	Glycine betaine
B7470_RS13360	COG0517	IMP dehydrogenase activity
B7470_RS13365	COG4176	ABC-type proline glycine betaine transport system permease component
B7470_RS13370	COG2113	Glycine betaine
B7470_RS13375	COG1473	amidohydrolase
B7470_RS13380	COG1288	antiporter activity
B7470_RS13395	COG0039	L-malate dehydrogenase activity
B7470_RS13410	COG3403	YqcI/YcgG family
B7470_RS13425	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
B7470_RS13430	COG1660	Displays ATPase and GTPase activities
B7470_RS13440	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
B7470_RS13455	COG2226	methyltransferase
B7470_RS13460	COG0583	DNA-binding transcription factor activity
B7470_RS13465	COG3458	cephalosporin-C deacetylase activity
B7470_RS13470	COG3541	Predicted nucleotidyltransferase
B7470_RS13475	COG0506	proline dehydrogenase activity
B7470_RS13480	COG1012	belongs to the aldehyde dehydrogenase family
B7470_RS13485	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B7470_RS13490	COG2508	Transcriptional regulator
B7470_RS13495	COG3689	TIGRFAM TIGR03943 family protein
B7470_RS13500	COG0701	Predicted permease
B7470_RS13505	COG2267	carboxylic ester hydrolase activity
B7470_RS13510	COG0492	ferredoxin-NADP+ reductase activity
B7470_RS13515	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B7470_RS13515	COG1587	Uroporphyrinogen-III synthase
B7470_RS13520	COG2146	nitrite reductase [NAD(P)H] activity
B7470_RS13525	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B7470_RS13530	COG0243	molybdopterin cofactor binding
B7470_RS13535	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B7470_RS13540	COG2223	nitrite transmembrane transporter activity
B7470_RS13550	COG1376	ErfK ybiS ycfS ynhG family protein
B7470_RS13565	COG0765	amino acid transport
B7470_RS13570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7470_RS13580	COG1714	RDD family
B7470_RS13590	COG1846	Transcriptional regulator
B7470_RS13605	COG2723	6-phospho-beta-galactosidase activity
B7470_RS13615	COG3209	COG3209 Rhs family protein
B7470_RS13625	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
B7470_RS13630	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
B7470_RS13635	COG1733	regulation of RNA biosynthetic process
B7470_RS13640	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7470_RS13645	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7470_RS13650	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7470_RS13655	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
B7470_RS13660	COG2814	Major facilitator Superfamily
B7470_RS13670	COG0697	spore germination
B7470_RS13675	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7470_RS13685	COG2364	Membrane
B7470_RS13695	COG1126	abc transporter atp-binding protein
B7470_RS13700	COG0765	amino acid transport
B7470_RS13705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7470_RS13710	COG0583	DNA-binding transcription factor activity
B7470_RS13715	COG0163	prenyltransferase activity
B7470_RS13720	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
B7470_RS13735	COG0596	Alpha beta hydrolase
B7470_RS13740	COG3104	oligopeptide transport
B7470_RS13745	COG5434	Belongs to the glycosyl hydrolase 28 family
B7470_RS13755	COG0697	spore germination
B7470_RS13765	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
B7470_RS13770	COG1136	(ABC) transporter
B7470_RS13775	COG0577	efflux transmembrane transporter activity
B7470_RS13780	COG0745	RESPONSE REGULATOR receiver
B7470_RS13785	COG3850	Histidine kinase
B7470_RS13785	COG5002	protein histidine kinase activity
B7470_RS13790	COG0457	Tetratricopeptide repeat
B7470_RS13810	COG0527	aspartate kinase activity
B7470_RS13815	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7470_RS13820	COG4605	iron ion homeostasis
B7470_RS13825	COG4604	ABC transporter, ATP-binding protein
B7470_RS13830	COG4607	ABC-type enterochelin transport system periplasmic component
B7470_RS13840	COG2814	Major facilitator Superfamily
B7470_RS13845	COG1309	transcriptional regulator
B7470_RS13850	COG0778	Nitroreductase
B7470_RS13855	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
B7470_RS13860	COG0640	Transcriptional regulator
B7470_RS13865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7470_RS13870	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B7470_RS13875	COG1012	belongs to the aldehyde dehydrogenase family
B7470_RS13880	COG4975	Glucose uptake
B7470_RS13885	COG1028	Short-chain dehydrogenase reductase Sdr
B7470_RS13890	COG4549	nuclear export factor GLE1
B7470_RS13895	COG1276	copper resistance
B7470_RS13895	COG2372	response to copper ion
B7470_RS13900	COG1349	DNA-binding transcription factor activity
B7470_RS13910	COG2213	PTS system mannitol-specific
B7470_RS13915	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7470_RS13920	COG0246	Mannitol dehydrogenase
B7470_RS13925	COG0473	3-isopropylmalate dehydrogenase activity
B7470_RS13930	COG0681	Belongs to the peptidase S26 family
B7470_RS13940	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B7470_RS13950	COG0561	phosphatase activity
B7470_RS13955	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
B7470_RS13960	COG1914	H( )-stimulated, divalent metal cation uptake system
B7470_RS13965	COG4336	lyase activity
B7470_RS13970	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
B7470_RS13975	COG1984	allophanate hydrolase subunit 2
B7470_RS13980	COG1414	Transcriptional regulator
B7470_RS13985	COG2755	lipolytic protein G-D-S-L family
B7470_RS13995	COG2329	Antibiotic biosynthesis monooxygenase
B7470_RS14000	COG0768	penicillin binding
B7470_RS14005	COG4989	oxidoreductase activity
B7470_RS14010	COG3711	transcriptional antiterminator
B7470_RS14015	COG0318	PFAM AMP-dependent synthetase and ligase
B7470_RS14020	COG2226	methyltransferase
B7470_RS14025	COG1028	Short-chain dehydrogenase reductase Sdr
B7470_RS14030	COG1917	Cupin 2, conserved barrel domain protein
B7470_RS14035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B7470_RS14040	COG3871	stress protein (general stress protein 26)
B7470_RS14050	COG2814	Major facilitator Superfamily
B7470_RS14055	COG1522	sequence-specific DNA binding
B7470_RS14060	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B7470_RS14060	COG0551	DNA topoisomerase type I activity
B7470_RS14065	COG0494	nUDIX hydrolase
B7470_RS14070	COG0028	Belongs to the TPP enzyme family
B7470_RS14100	COG1914	H( )-stimulated, divalent metal cation uptake system
B7470_RS14105	COG2261	transglycosylase associated protein
B7470_RS14110	COG4876	unkown
B7470_RS14115	COG2217	Heavy metal translocating P-type atpase
B7470_RS14120	COG3729	General stress protein
B7470_RS14125	COG0662	Cupin 2, conserved barrel domain protein
B7470_RS14130	COG2329	Antibiotic biosynthesis monooxygenase
B7470_RS14135	COG3546	catalase activity
B7470_RS14140	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B7470_RS14145	COG3290	protein histidine kinase activity
B7470_RS14150	COG4565	transcriptional regulatory protein
B7470_RS14155	COG1301	dicarboxylic acid transport
B7470_RS14160	COG0628	permease
B7470_RS14165	COG1131	(ABC) transporter
B7470_RS14170	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
B7470_RS14180	COG1960	acyl-CoA dehydrogenase activity
B7470_RS14195	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
B7470_RS14200	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B7470_RS14205	COG1181	Belongs to the D-alanine--D-alanine ligase family
B7470_RS14210	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
B7470_RS14220	COG0513	Belongs to the DEAD box helicase family
B7470_RS14225	COG3402	PFAM membrane-flanked domain
B7470_RS14230	COG3428	Bacterial PH domain
B7470_RS14235	COG0705	Rhomboid family
B7470_RS14240	COG0736	holo-[acyl-carrier-protein] synthase activity
B7470_RS14245	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
B7470_RS14250	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B7470_RS14255	COG0864	Transcriptional regulator
B7470_RS14260	COG2337	Toxic component of a toxin-antitoxin (TA) module
B7470_RS14265	COG1366	Belongs to the anti-sigma-factor antagonist family
B7470_RS14270	COG1366	Belongs to the anti-sigma-factor antagonist family
B7470_RS14275	COG2172	sigma factor antagonist activity
B7470_RS14280	COG2208	phosphoserine phosphatase activity
B7470_RS14285	COG1366	Belongs to the anti-sigma-factor antagonist family
B7470_RS14290	COG2172	sigma factor antagonist activity
B7470_RS14295	COG1191	sigma factor activity
B7470_RS14300	COG2208	phosphoserine phosphatase activity
B7470_RS14315	COG1673	EVE domain
B7470_RS14320	COG1846	Transcriptional regulator
B7470_RS14325	COG2183	response to ionizing radiation
B7470_RS14335	COG3091	SprT-like family
B7470_RS14375	COG0582	viral genome integration into host DNA
B7470_RS14380	COG2856	Zn peptidase
B7470_RS14385	COG1396	sequence-specific DNA binding
B7470_RS14410	COG1674	ftsk spoiiie
B7470_RS14415	COG2946	Replication initiation factor
B7470_RS14455	COG0433	COG0433 Predicted ATPase
B7470_RS14465	COG5644	endopeptidase inhibitor activity
B7470_RS14475	COG0741	lytic transglycosylase activity
B7470_RS14475	COG0791	NLP P60 protein
B7470_RS14490	COG0457	Tetratricopeptide repeat
B7470_RS14520	COG0583	DNA-binding transcription factor activity
B7470_RS14525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B7470_RS14535	COG5444	nuclease activity
B7470_RS14540	COG1476	TRANSCRIPTIONal
B7470_RS14565	COG0693	protein deglycase activity
B7470_RS14570	COG1278	Cold shock
B7470_RS14575	COG1329	Transcriptional regulator
B7470_RS14585	COG0697	spore germination
B7470_RS14590	COG2207	Transcriptional regulator
B7470_RS14590	COG1917	Cupin 2, conserved barrel domain protein
B7470_RS14600	COG2207	Transcriptional regulator
B7470_RS14600	COG3708	Transcriptional regulator
B7470_RS14605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7470_RS14620	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
B7470_RS14635	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7470_RS14640	COG1309	transcriptional regulator
B7470_RS14645	COG0697	spore germination
B7470_RS14650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7470_RS14655	COG2030	dehydratase
B7470_RS14660	COG3545	Serine hydrolase
B7470_RS14670	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B7470_RS14675	COG0640	Transcriptional regulator
B7470_RS14680	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B7470_RS14690	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B7470_RS14695	COG0697	spore germination
B7470_RS14700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7470_RS14705	COG0076	glutamate decarboxylase activity
B7470_RS14710	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B7470_RS14715	COG0640	Transcriptional regulator
B7470_RS14720	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B7470_RS14735	COG4585	Histidine kinase
B7470_RS14740	COG2197	response regulator
B7470_RS14745	COG2409	Drug exporters of the RND superfamily
B7470_RS14750	COG0596	Alpha beta hydrolase
B7470_RS14755	COG1811	Na channel or pump
B7470_RS14760	COG0789	Transcriptional regulator
B7470_RS14760	COG4978	Transcriptional regulator
B7470_RS14765	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
B7470_RS14770	COG0778	Nitroreductase
B7470_RS14775	COG0346	lactoylglutathione lyase activity
B7470_RS14780	COG2259	Doxx family
B7470_RS14785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B7470_RS14810	COG2323	membrane
B7470_RS14815	COG0071	Belongs to the small heat shock protein (HSP20) family
B7470_RS14830	COG1309	transcriptional regulator
B7470_RS14840	COG0456	acetyltransferase
B7470_RS14850	COG1113	amino acid transport
B7470_RS14855	COG2318	DinB family
B7470_RS14860	COG1846	Transcriptional regulator
B7470_RS14865	COG1033	growth of symbiont in host cell
B7470_RS14865	COG2409	Drug exporters of the RND superfamily
B7470_RS14870	COG0778	Nitroreductase
B7470_RS14875	COG1846	Transcriptional regulator
B7470_RS14880	COG2814	Major facilitator Superfamily
B7470_RS14885	COG0730	response to heat
B7470_RS14890	COG1802	Transcriptional regulator
B7470_RS14895	COG1388	LysM domain
B7470_RS14895	COG3858	chitin binding
B7470_RS14900	COG1819	glycosyl
B7470_RS14910	COG1785	Belongs to the alkaline phosphatase family
B7470_RS14915	COG5646	InterPro IPR014922
B7470_RS14925	COG0454	-acetyltransferase
B7470_RS14930	COG1078	dGTPase activity
B7470_RS14935	COG1388	LysM domain
B7470_RS14940	COG2814	Major facilitator Superfamily
B7470_RS14945	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B7470_RS14960	COG2723	6-phospho-beta-galactosidase activity
B7470_RS14965	COG2188	Transcriptional regulator
B7470_RS14970	COG1940	carbohydrate kinase activity
B7470_RS14980	COG4124	Belongs to the glycosyl hydrolase 26 family
B7470_RS15025	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
B7470_RS15030	COG0802	atpase or kinase
B7470_RS15035	COG1214	PFAM Peptidase M22, glycoprotease
B7470_RS15040	COG0456	acetyltransferase
B7470_RS15045	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
B7470_RS15050	COG0488	(ABC) transporter
B7470_RS15055	COG0315	cyclic pyranopterin monophosphate synthase activity
B7470_RS15060	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
B7470_RS15065	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B7470_RS15070	COG0805	protein transport
B7470_RS15085	COG1266	CAAX protease self-immunity
B7470_RS15095	COG0459	protein refolding
B7470_RS15110	COG0457	Tetratricopeptide repeat
B7470_RS15115	COG1063	alcohol dehydrogenase
B7470_RS15120	COG2211	Major facilitator Superfamily
B7470_RS15125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B7470_RS15135	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
B7470_RS15140	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
B7470_RS15145	COG4260	virion core protein, lumpy skin disease virus
B7470_RS15155	COG2814	Major facilitator Superfamily
B7470_RS15160	COG1063	alcohol dehydrogenase
B7470_RS15165	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
B7470_RS15170	COG0823	Involved in the tonB-independent uptake of proteins
B7470_RS15190	COG2267	carboxylic ester hydrolase activity
B7470_RS15200	COG2132	Multicopper oxidase
B7470_RS15205	COG1113	amino acid transport
B7470_RS15215	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
B7470_RS15220	COG0714	Associated with various cellular activities
B7470_RS15225	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
B7470_RS15230	COG1305	Transglutaminase-like
B7470_RS15235	COG0519	Catalyzes the synthesis of GMP from XMP
B7470_RS15235	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B7470_RS15245	COG2252	PERMEase
B7470_RS15250	COG3064	Membrane
B7470_RS15260	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
B7470_RS15270	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
B7470_RS15275	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
B7470_RS15280	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B7470_RS15285	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
B7470_RS15290	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B7470_RS15295	COG0047	phosphoribosylformylglycinamidine synthase activity
B7470_RS15300	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B7470_RS15305	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
B7470_RS15310	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
B7470_RS15315	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
B7470_RS15320	COG0138	bifunctional purine biosynthesis protein purh
B7470_RS15325	COG0151	Belongs to the GarS family
B7470_RS15330	COG1522	sequence-specific DNA binding
B7470_RS15335	COG0531	amino acid
B7470_RS15345	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
B7470_RS15350	COG1470	cell adhesion involved in biofilm formation
B7470_RS15355	COG4496	protein, YerC YecD
B7470_RS15360	COG0069	glutamate synthase activity
B7470_RS15365	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
B7470_RS15370	COG0210	DNA helicase
B7470_RS15375	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
B7470_RS15380	COG4851	CamS sex pheromone cAM373 precursor
B7470_RS15390	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
B7470_RS15395	COG1285	pathogenesis
B7470_RS15400	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B7470_RS15405	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B7470_RS15410	COG0154	amidase activity
B7470_RS15415	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B7470_RS15420	COG1309	transcriptional regulator
B7470_RS15425	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B7470_RS15430	COG1597	lipid kinase activity
B7470_RS15435	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
B7470_RS15465	COG5444	nuclease activity
B7470_RS15475	COG0457	Tetratricopeptide repeat
B7470_RS15485	COG0217	transcriptional regulatory protein
B7470_RS15495	COG1309	transcriptional regulator
B7470_RS15510	COG3546	catalase activity
B7470_RS15515	COG0454	-acetyltransferase
B7470_RS15525	COG5578	integral membrane protein
B7470_RS15530	COG2972	Histidine kinase
B7470_RS15540	COG1653	transport
B7470_RS15545	COG1175	transmembrane transport
B7470_RS15550	COG0395	ABC-type sugar transport system, permease component
B7470_RS15555	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
B7470_RS15560	COG2207	Transcriptional regulator
B7470_RS15565	COG2755	lipolytic protein G-D-S-L family
B7470_RS15575	COG5578	integral membrane protein
B7470_RS15580	COG3401	FG-GAP repeat protein
B7470_RS15585	COG3401	FG-GAP repeat protein
B7470_RS15590	COG2755	lipolytic protein G-D-S-L family
B7470_RS15605	COG1653	transport
B7470_RS15610	COG4209	transmembrane transport
B7470_RS15615	COG0395	ABC-type sugar transport system, permease component
B7470_RS15620	COG1486	melibiose metabolic process
B7470_RS15625	COG2323	membrane
B7470_RS15630	COG2329	Antibiotic biosynthesis monooxygenase
B7470_RS15635	COG0346	lactoylglutathione lyase activity
B7470_RS15650	COG5583	Uncharacterized small protein (DUF2292)
B7470_RS15655	COG0670	Belongs to the BI1 family
B7470_RS15660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B7470_RS15670	COG3328	transposase activity
B7470_RS15680	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
B7470_RS15680	COG2124	cytochrome p450
B7470_RS15690	COG1368	sulfuric ester hydrolase activity
B7470_RS15695	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
B7470_RS15700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B7470_RS15705	COG1442	glycosyl transferase family 8
B7470_RS15710	COG1216	Glycosyl transferase, family 2
B7470_RS15715	COG1442	glycosyl transferase family 8
B7470_RS15720	COG2223	nitrite transmembrane transporter activity
B7470_RS15725	COG1011	Hydrolase
B7470_RS15730	COG0531	amino acid
B7470_RS15735	COG1012	belongs to the aldehyde dehydrogenase family
B7470_RS15740	COG0840	transmembrane signaling receptor activity
B7470_RS15745	COG0488	(ABC) transporter
B7470_RS15755	COG0789	Transcriptional regulator
B7470_RS15760	COG2814	Major facilitator Superfamily
B7470_RS15775	COG0488	(ABC) transporter
B7470_RS15780	COG0513	Belongs to the DEAD box helicase family
B7470_RS15790	COG3866	Pectate lyase
B7470_RS15795	COG0471	metal ion transport
B7470_RS15800	COG3290	protein histidine kinase activity
B7470_RS15805	COG4565	transcriptional regulatory protein
B7470_RS15810	COG3181	Tripartite tricarboxylate transporter family receptor
B7470_RS15815	COG2851	Citrate transporter
B7470_RS15820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B7470_RS15825	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
B7470_RS15830	COG1254	Belongs to the acylphosphatase family
B7470_RS15835	COG2258	MOSC domain
B7470_RS15855	COG0024	Methionine aminopeptidase
B7470_RS15860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B7470_RS15860	COG1263	PTS System
B7470_RS15865	COG1368	sulfuric ester hydrolase activity
B7470_RS15880	COG1115	amino acid carrier protein
B7470_RS15890	COG0697	spore germination
B7470_RS15895	COG1263	PTS System
B7470_RS15895	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B7470_RS15900	COG0366	Alpha amylase catalytic
B7470_RS15905	COG2188	Transcriptional regulator
B7470_RS15910	COG0778	Nitroreductase
B7470_RS15915	COG0737	Belongs to the 5'-nucleotidase family
B7470_RS15920	COG0693	protein deglycase activity
B7470_RS15930	COG2814	Major facilitator Superfamily
B7470_RS15935	COG4840	Belongs to the UPF0435 family
B7470_RS15940	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B7470_RS15945	COG4980	gas vesicle protein
B7470_RS15950	COG1295	ribonuclease BN
B7470_RS15955	COG0477	Major facilitator Superfamily
B7470_RS15960	COG0387	Pfam Sodium calcium exchanger
B7470_RS15970	COG0668	transmembrane transport
B7470_RS15975	COG0535	radical SAM domain protein
B7470_RS15985	COG0726	polysaccharide deacetylase
B7470_RS15990	COG2084	Dehydrogenase
B7470_RS15995	COG0598	Magnesium transport protein CorA
B7470_RS16000	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
B7470_RS16005	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
B7470_RS16015	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B7470_RS16020	COG4637	Psort location Cytoplasmic, score
B7470_RS16030	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B7470_RS16035	COG0022	dehydrogenase e1 component
B7470_RS16040	COG0508	dehydrogenase complex catalyzes the overall conversion of
B7470_RS16045	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B7470_RS16050	COG3284	Transcriptional regulator
B7470_RS16060	COG1742	UPF0060 membrane protein
B7470_RS16085	COG4842	Belongs to the WXG100 family
B7470_RS16090	COG1486	melibiose metabolic process
B7470_RS16095	COG1737	Transcriptional regulator
B7470_RS16100	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B7470_RS16100	COG1263	PTS System
B7470_RS16105	COG5434	Belongs to the glycosyl hydrolase 28 family
B7470_RS16110	COG1132	(ABC) transporter
B7470_RS16115	COG1132	(ABC) transporter
B7470_RS16120	COG2259	Doxx family
B7470_RS16125	COG2514	catechol 2,3-dioxygenase activity
B7470_RS16130	COG4977	sequence-specific DNA binding
B7470_RS16130	COG1917	Cupin 2, conserved barrel domain protein
B7470_RS16135	COG2814	Major facilitator Superfamily
B7470_RS16140	COG1082	Xylose isomerase domain protein TIM barrel
B7470_RS16150	COG4585	Histidine kinase
B7470_RS16155	COG2197	response regulator
B7470_RS16160	COG1131	(ABC) transporter
B7470_RS16165	COG0842	Transport permease protein
B7470_RS16165	COG1511	domain protein
B7470_RS16170	COG0842	Transport permease protein
B7470_RS16175	COG1695	Transcriptional regulator
B7470_RS16180	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
B7470_RS16185	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
B7470_RS16190	COG1309	transcriptional regulator
B7470_RS16195	COG2814	Major facilitator Superfamily
B7470_RS16200	COG2318	DinB family
B7470_RS16210	COG1846	Transcriptional regulator
B7470_RS16220	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B7470_RS16225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7470_RS16230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7470_RS16235	COG0384	phenazine biosynthesis protein PhzF
B7470_RS16240	COG0778	Nitroreductase
B7470_RS16255	COG1090	epimerase
B7470_RS16270	COG2814	Major facilitator Superfamily
B7470_RS16285	COG3103	Sh3 type 3 domain protein
B7470_RS16290	COG5658	integral membrane protein
B7470_RS16295	COG0596	Alpha beta hydrolase
B7470_RS16300	COG0463	Glycosyl transferase, family 2
B7470_RS16305	COG4485	Bacterial membrane protein, YfhO
B7470_RS16310	COG1988	membrane-bound metal-dependent
B7470_RS16315	COG1194	a g-specific adenine glycosylase
B7470_RS16325	COG1028	Short-chain dehydrogenase reductase Sdr
B7470_RS16340	COG3557	Belongs to the UPF0374 family
B7470_RS16345	COG1132	(ABC) transporter
B7470_RS16350	COG4129	membrane
B7470_RS16355	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
B7470_RS16360	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B7470_RS16365	COG0735	belongs to the Fur family
B7470_RS16475	COG4326	sporulation control protein
B7470_RS16485	COG5577	PFAM Coat F domain
B7470_RS16490	COG3340	Belongs to the peptidase S51 family
B7470_RS16495	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
B7470_RS16510	COG0753	catalase activity
B7470_RS16515	COG1116	anion transmembrane transporter activity
B7470_RS16520	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B7470_RS16525	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B7470_RS16530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7470_RS16540	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
B7470_RS16550	COG1476	TRANSCRIPTIONal
B7470_RS16560	COG3382	B3 4 domain protein
B7470_RS16565	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
B7470_RS16575	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
B7470_RS16580	COG0789	Transcriptional regulator
B7470_RS16585	COG1664	Polymer-forming cytoskeletal
B7470_RS16590	COG1664	Polymer-forming cytoskeletal
B7470_RS16595	COG2766	serine protein kinase
B7470_RS16600	COG2718	Belongs to the UPF0229 family
B7470_RS16605	COG1846	Transcriptional regulator
B7470_RS16610	COG1566	PFAM secretion protein HlyD family protein
B7470_RS16615	COG2814	Major facilitator Superfamily
B7470_RS16620	COG0655	NAD(P)H dehydrogenase (quinone) activity
B7470_RS16640	COG1725	Transcriptional regulator
B7470_RS16645	COG1131	(ABC) transporter
B7470_RS16650	COG1131	(ABC) transporter
B7470_RS16655	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
B7470_RS16660	COG1278	Cold shock
B7470_RS16670	COG1464	Belongs to the NlpA lipoprotein family
B7470_RS16675	COG3706	GGDEF domain
B7470_RS16680	COG1823	symporter activity
B7470_RS16685	COG5444	nuclease activity
B7470_RS16710	COG0582	viral genome integration into host DNA
B7470_RS16715	COG2946	Replication initiation factor
B7470_RS16765	COG5644	endopeptidase inhibitor activity
B7470_RS16770	COG0791	NLP P60 protein
B7470_RS16770	COG0741	lytic transglycosylase activity
B7470_RS16790	COG0457	Tetratricopeptide repeat
B7470_RS16820	COG1525	nuclease
B7470_RS16820	COG4085	toxin activity
B7470_RS16820	COG0737	Belongs to the 5'-nucleotidase family
B7470_RS16825	COG3764	Sortase (surface protein transpeptidase)
B7470_RS16830	COG0564	pseudouridine synthase activity
B7470_RS16840	COG0517	IMP dehydrogenase activity
B7470_RS16845	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B7470_RS16850	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B7470_RS16850	COG3153	acetyltransferase
B7470_RS16855	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B7470_RS16860	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
B7470_RS16865	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
B7470_RS16870	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B7470_RS16875	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
B7470_RS16880	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B7470_RS16885	COG4585	Histidine kinase
B7470_RS16885	COG2203	Gaf domain
B7470_RS16890	COG2197	response regulator
B7470_RS16895	COG0431	NADPH-dependent FMN reductase
B7470_RS16910	COG1388	LysM domain
B7470_RS16910	COG0791	NLP P60 protein
B7470_RS16915	COG1959	2 iron, 2 sulfur cluster binding
B7470_RS16920	COG0668	transmembrane transport
B7470_RS16925	COG2719	SpoVR family
B7470_RS16930	COG1785	Belongs to the alkaline phosphatase family
B7470_RS16935	COG0791	NLP P60 protein
B7470_RS16935	COG1388	LysM domain
B7470_RS16940	COG0583	DNA-binding transcription factor activity
B7470_RS16945	COG0372	Belongs to the citrate synthase family
B7470_RS16950	COG1028	Short-chain dehydrogenase reductase Sdr
B7470_RS16955	COG0531	amino acid
B7470_RS16960	COG0733	neurotransmitter:sodium symporter activity
B7470_RS16965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7470_RS16970	COG0456	acetyltransferase
B7470_RS16985	COG1595	DNA-templated transcription, initiation
B7470_RS16990	COG0667	Aldo Keto reductase
B7470_RS16995	COG0204	Acyl-transferase
B7470_RS17000	COG1253	flavin adenine dinucleotide binding
B7470_RS17005	COG0789	Transcriptional regulator
B7470_RS17015	COG1253	flavin adenine dinucleotide binding
B7470_RS17020	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B7470_RS17025	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B7470_RS17030	COG0584	glycerophosphoryl diester phosphodiesterase
B7470_RS17040	COG0668	transmembrane transport
B7470_RS17045	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
B7470_RS17050	COG0726	polysaccharide deacetylase
B7470_RS17055	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B7470_RS17060	COG1757	Na H antiporter
B7470_RS17065	COG0589	response to stress
B7470_RS17075	COG1132	(ABC) transporter
B7470_RS17080	COG1132	(ABC) transporter
B7470_RS17085	COG0702	epimerase
B7470_RS17110	COG0189	ligase activity
B7470_RS17115	COG0189	ligase activity
B7470_RS17120	COG4399	Belongs to the UPF0754 family
B7470_RS17125	COG3679	Belongs to the UPF0342 family
B7470_RS17135	COG0561	phosphatase activity
B7470_RS17140	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B7470_RS17145	COG0475	glutathione-regulated potassium exporter activity
B7470_RS17150	COG0490	domain, Protein
B7470_RS17160	COG1024	Enoyl-CoA hydratase
B7470_RS17170	COG4152	abc transporter atp-binding protein
B7470_RS17175	COG1668	transmembrane transport
B7470_RS17180	COG0420	3'-5' exonuclease activity
B7470_RS17185	COG4717	serine-type aminopeptidase activity
B7470_RS17190	COG3481	metal-dependent phosphohydrolase, HD sub domain
B7470_RS17200	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B7470_RS17230	COG1846	Transcriptional regulator
B7470_RS17235	COG4980	gas vesicle protein
B7470_RS17250	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
B7470_RS17255	COG0537	adenosine 5'-monophosphoramidase activity
B7470_RS17260	COG1131	(ABC) transporter
B7470_RS17265	COG4473	ABC transporter
B7470_RS17275	COG1473	amidohydrolase
B7470_RS17280	COG3069	C4-dicarboxylate transmembrane transporter activity
B7470_RS17290	COG2329	Antibiotic biosynthesis monooxygenase
B7470_RS17295	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B7470_RS17300	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
B7470_RS17315	COG1309	transcriptional regulator
B7470_RS17320	COG1511	domain protein
B7470_RS17325	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B7470_RS17330	COG4377	Putative membrane peptidase family (DUF2324)
B7470_RS17340	COG1363	Peptidase, m42
B7470_RS17345	COG4405	Protein conserved in bacteria
B7470_RS17350	COG1301	dicarboxylic acid transport
B7470_RS17360	COG1234	tRNA 3'-trailer cleavage
B7470_RS17365	COG0095	Lipoate-protein ligase
B7470_RS17370	COG0702	epimerase
B7470_RS17375	COG0318	PFAM AMP-dependent synthetase and ligase
B7470_RS17385	COG0501	Belongs to the peptidase M48B family
B7470_RS17395	COG0456	acetyltransferase
B7470_RS17400	COG0604	alcohol dehydrogenase
B7470_RS17405	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
B7470_RS17410	COG0406	alpha-ribazole phosphatase activity
B7470_RS17415	COG0183	Belongs to the thiolase family
B7470_RS17420	COG0318	PFAM AMP-dependent synthetase and ligase
B7470_RS17425	COG1268	BioY protein
B7470_RS17430	COG0840	transmembrane signaling receptor activity
B7470_RS17440	COG1028	Short-chain dehydrogenase reductase Sdr
B7470_RS17450	COG4903	ComK protein
B7470_RS17455	COG1028	Short-chain dehydrogenase reductase Sdr
B7470_RS17465	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B7470_RS17480	COG0398	Pfam SNARE associated Golgi protein
B7470_RS17485	COG0681	Belongs to the peptidase S26 family
B7470_RS17490	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B7470_RS17495	COG1846	Transcriptional regulator
B7470_RS17510	COG0738	Major facilitator superfamily
B7470_RS17515	COG0673	inositol 2-dehydrogenase activity
B7470_RS17520	COG0561	phosphatase activity
B7470_RS17525	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B7470_RS17530	COG1609	Transcriptional regulator
B7470_RS17535	COG3180	Ammonia monooxygenase
B7470_RS17540	COG0477	Major facilitator Superfamily
B7470_RS17540	COG2814	Major facilitator Superfamily
B7470_RS17545	COG4533	DNA binding
B7470_RS17565	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
B7470_RS17570	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
B7470_RS17575	COG1074	ATP-dependent DNA helicase activity
B7470_RS17580	COG0420	3'-5' exonuclease activity
B7470_RS17585	COG0419	ATPase involved in DNA repair
B7470_RS17590	COG1403	HNH endonuclease
B7470_RS17630	COG5337	Spore coat protein CotH
B7470_RS17635	COG0179	Fumarylacetoacetate (FAA) hydrolase
B7470_RS17645	COG1404	Belongs to the peptidase S8 family
B7470_RS17655	COG0367	asparagine synthase
B7470_RS17660	COG1562	ergosterol biosynthetic process
B7470_RS17665	COG0534	Mate efflux family protein
B7470_RS17670	COG1917	Cupin 2, conserved barrel domain protein
B7470_RS17670	COG2207	Transcriptional regulator
B7470_RS17675	COG1609	Transcriptional regulator
B7470_RS17680	COG0673	inositol 2-dehydrogenase activity
B7470_RS17685	COG2318	DinB family
B7470_RS17690	COG1279	arginine transmembrane transporter activity
B7470_RS17695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7470_RS17700	COG1357	PFAM Pentapeptide repeats (8 copies)
B7470_RS17705	COG2267	carboxylic ester hydrolase activity
B7470_RS17715	COG2153	protein acetylation
B7470_RS17720	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
B7470_RS17720	COG0646	methionine synthase
B7470_RS17725	COG1666	GTP binding
B7470_RS17730	COG2996	Protein conserved in bacteria
B7470_RS17740	COG1307	EDD domain protein, DegV family
B7470_RS17745	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B7470_RS17760	COG0561	phosphatase activity
B7470_RS17765	COG1073	alpha beta
B7470_RS17770	COG2151	metal-sulfur cluster biosynthetic enzyme
B7470_RS17790	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
B7470_RS17795	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
B7470_RS17805	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B7470_RS17810	COG0505	Belongs to the CarA family
B7470_RS17815	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B7470_RS17820	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
B7470_RS17840	COG2267	carboxylic ester hydrolase activity
B7470_RS17850	COG1744	ABC transporter substrate-binding protein PnrA-like
B7470_RS17865	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B7470_RS17870	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B7470_RS17875	COG5504	Zn-dependent protease
B7470_RS17880	COG0444	Belongs to the ABC transporter superfamily
B7470_RS17885	COG4608	Belongs to the ABC transporter superfamily
B7470_RS17895	COG0601	transmembrane transport
B7470_RS17900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B7470_RS17910	COG0180	Tryptophanyl-tRNA synthetase
B7470_RS17915	COG4166	transmembrane transport
B7470_RS17920	COG0601	transmembrane transport
B7470_RS17925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B7470_RS17930	COG0444	Belongs to the ABC transporter superfamily
B7470_RS17935	COG4608	Belongs to the ABC transporter superfamily
B7470_RS17940	COG2814	Major facilitator Superfamily
B7470_RS17945	COG0456	acetyltransferase
B7470_RS17950	COG1393	Belongs to the ArsC family
B7470_RS17955	COG0861	Integral membrane protein TerC family
B7470_RS17960	COG4862	establishment of competence for transformation
B7470_RS17965	COG4469	Competence protein
B7470_RS17970	COG1164	Oligoendopeptidase f
B7470_RS17990	COG2346	COG2346, Truncated hemoglobins
B7470_RS17995	COG0741	lytic transglycosylase activity
B7470_RS18000	COG4116	CYTH
B7470_RS18010	COG2357	RelA SpoT domain protein
B7470_RS18015	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
B7470_RS18020	COG0564	pseudouridine synthase activity
B7470_RS18025	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
B7470_RS18030	COG0475	glutathione-regulated potassium exporter activity
B7470_RS18030	COG0569	domain protein
B7470_RS18035	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
B7470_RS18040	COG0352	thiamine-phosphate diphosphorylase activity
B7470_RS18045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B7470_RS18050	COG2104	thiamine diphosphate biosynthetic process
B7470_RS18055	COG2022	thiamine diphosphate biosynthetic process
B7470_RS18060	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B7470_RS18065	COG0351	phosphomethylpyrimidine kinase
B7470_RS18070	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
B7470_RS18125	COG0210	DNA helicase
B7470_RS18135	COG2153	protein acetylation
B7470_RS18140	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
B7470_RS18145	COG2382	esterase
B7470_RS18150	COG0626	cystathionine gamma-synthase activity
B7470_RS18155	COG0626	cystathionine gamma-synthase activity
B7470_RS18160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B7470_RS18165	COG5505	Protein of unknown function (DUF819)
B7470_RS18200	COG1396	sequence-specific DNA binding
B7470_RS18275	COG0457	Tetratricopeptide repeat
B7470_RS18280	COG5444	nuclease activity
B7470_RS18290	COG3328	transposase activity
B7470_RS18350	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
B7470_RS18360	COG3711	transcriptional antiterminator
B7470_RS18360	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7470_RS18365	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B7470_RS18365	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7470_RS18365	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B7470_RS18370	COG1482	cell wall glycoprotein biosynthetic process
B7470_RS18380	COG3328	transposase activity
B7470_RS18385	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B7470_RS18395	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B7470_RS18415	COG0109	protoheme IX farnesyltransferase activity
B7470_RS18425	COG0726	polysaccharide deacetylase
B7470_RS18440	COG5504	Zn-dependent protease
B7470_RS18445	COG2205	protein histidine kinase activity
B7470_RS18460	COG2427	Protein of unknown function (DUF1641)
B7470_RS18470	COG1051	belongs to the nudix hydrolase family
B7470_RS18480	COG2124	cytochrome p450
B7470_RS18485	COG1819	glycosyl
B7470_RS18495	COG1587	Uroporphyrinogen-III synthase
B7470_RS18500	COG0390	transport system, permease component
B7470_RS18505	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B7470_RS18510	COG0697	spore germination
B7470_RS18525	COG1252	NADH dehydrogenase
B7470_RS18530	COG1904	glucuronate isomerase
B7470_RS18535	COG2211	Major facilitator Superfamily
B7470_RS18540	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
B7470_RS18545	COG1063	alcohol dehydrogenase
B7470_RS18550	COG1312	Catalyzes the dehydration of D-mannonate
B7470_RS18555	COG1028	Short-chain dehydrogenase reductase Sdr
B7470_RS18560	COG2271	Major facilitator Superfamily
B7470_RS18565	COG1609	Transcriptional regulator
B7470_RS18570	COG0246	Mannitol dehydrogenase
B7470_RS18575	COG2721	sulfolactate sulfo-lyase activity
B7470_RS18580	COG0730	response to heat
B7470_RS18585	COG2318	DinB family
B7470_RS18605	COG0457	Tetratricopeptide repeat
B7470_RS18620	COG3409	Peptidoglycan-binding domain 1 protein
B7470_RS18620	COG1388	LysM domain
B7470_RS18620	COG5632	N-Acetylmuramoyl-L-alanine amidase
B7470_RS18630	COG4195	phage-related replication protein
B7470_RS18635	COG3546	catalase activity
B7470_RS18640	COG2856	Zn peptidase
B7470_RS18645	COG1396	sequence-specific DNA binding
B7470_RS18655	COG1522	sequence-specific DNA binding
B7470_RS18660	COG1484	DNA-dependent DNA replication
B7470_RS18680	COG1595	DNA-templated transcription, initiation
B7470_RS18685	COG3728	DNA packaging
B7470_RS18685	COG5484	DNA packaging
B7470_RS18690	COG1783	phage Terminase large subunit
B7470_RS18695	COG5518	Phage portal protein
B7470_RS18700	COG0338	D12 class N6 adenine-specific DNA methyltransferase
B7470_RS18705	COG4653	Phage capsid family
B7470_RS18755	COG3953	SLT domain
B7470_RS18755	COG3953	SLT domain
B7470_RS18755	COG5412	phage tail tape measure protein
B7470_RS18755	COG3953	SLT domain
B7470_RS18755	COG5412	phage tail tape measure protein
B7470_RS18755	COG5412	phage tail tape measure protein
B7470_RS18760	COG1652	LysM domain
B7470_RS18765	COG4193	domain, Protein
B7470_RS18775	COG3628	GPW Gp25 family protein
B7470_RS18780	COG3299	homolog of phage Mu protein gp47
B7470_RS18785	COG3778	Protein conserved in bacteria
B7470_RS18825	COG3409	Peptidoglycan-binding domain 1 protein
B7470_RS18825	COG5632	N-Acetylmuramoyl-L-alanine amidase
B7470_RS18840	COG0306	phosphate transporter
B7470_RS18845	COG1392	Phosphate transport regulator
B7470_RS18850	COG0531	amino acid
B7470_RS18855	COG0346	lactoylglutathione lyase activity
B7470_RS18860	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
B7470_RS18865	COG0463	Glycosyl transferase, family 2
B7470_RS18870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B7470_RS18875	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B7470_RS18880	COG2362	D-Aminopeptidase
B7470_RS18885	COG0601	transmembrane transport
B7470_RS18890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B7470_RS18895	COG0444	Belongs to the ABC transporter superfamily
B7470_RS18900	COG4166	transmembrane transport
B7470_RS18905	COG1619	proteins homologs of microcin C7 resistance protein MccF
B7470_RS18910	COG4948	Mandelate Racemase Muconate Lactonizing
B7470_RS18915	COG0791	NLP P60 protein
B7470_RS18920	COG4608	Belongs to the ABC transporter superfamily
B7470_RS18925	COG2706	6-phosphogluconolactonase activity
B7470_RS18935	COG1607	acyl-coa hydrolase
B7470_RS18940	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B7470_RS18940	COG1017	nitric oxide dioxygenase activity
B7470_RS18950	COG2323	membrane
B7470_RS18955	COG2318	DinB family
B7470_RS18960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B7470_RS18965	COG2076	Multidrug Resistance protein
B7470_RS18970	COG2076	Multidrug Resistance protein
B7470_RS18975	COG0788	formyltetrahydrofolate deformylase activity
B7470_RS18980	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
B7470_RS18985	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
B7470_RS18990	COG1764	response to oxidative stress
B7470_RS18995	COG1846	Transcriptional regulator
B7470_RS19000	COG1764	response to oxidative stress
B7470_RS19010	COG0590	tRNA wobble adenosine to inosine editing
B7470_RS19015	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
B7470_RS19020	COG1404	Belongs to the peptidase S8 family
B7470_RS19025	COG1366	Belongs to the anti-sigma-factor antagonist family
B7470_RS19030	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
B7470_RS19035	COG1122	ATPase activity
B7470_RS19040	COG4721	ABC-type cobalt transport system, permease component
B7470_RS19050	COG0745	RESPONSE REGULATOR receiver
B7470_RS19055	COG5002	protein histidine kinase activity
B7470_RS19055	COG3850	Histidine kinase
B7470_RS19060	COG3212	peptidase
B7470_RS19065	COG3212	peptidase
B7470_RS19080	COG2239	Acts as a magnesium transporter
B7470_RS19085	COG0789	Transcriptional regulator
B7470_RS19100	COG1846	Transcriptional regulator
B7470_RS19105	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B7470_RS19110	COG0726	polysaccharide deacetylase
B7470_RS19115	COG1408	metallophosphoesterase
B7470_RS19125	COG0463	Glycosyl transferase, family 2
B7470_RS19130	COG3285	dna ligase
B7470_RS19130	COG1793	dna ligase
B7470_RS19135	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
B7470_RS19140	COG3300	MHYT domain
B7470_RS19140	COG5001	Diguanylate cyclase
B7470_RS19145	COG0586	Pfam SNARE associated Golgi protein
B7470_RS19150	COG0861	Integral membrane protein TerC family
B7470_RS19155	COG1191	sigma factor activity
B7470_RS19175	COG0501	Belongs to the peptidase M48B family
B7470_RS19180	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B7470_RS19200	COG3594	Acyltransferase
B7470_RS19205	COG5002	protein histidine kinase activity
B7470_RS19210	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B7470_RS19215	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
B7470_RS19220	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
B7470_RS19225	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B7470_RS19230	COG0436	Aminotransferase
B7470_RS19235	COG1850	ribulose-bisphosphate carboxylase activity
B7470_RS19240	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
B7470_RS19245	COG0235	Class ii aldolase
B7470_RS19250	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
B7470_RS19255	COG3339	Conserved Protein
B7470_RS19270	COG3852	Histidine kinase
B7470_RS19275	COG1846	Transcriptional regulator
B7470_RS19280	COG1360	Flagellar Motor Protein
B7470_RS19285	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
B7470_RS19290	COG0542	response to heat
B7470_RS19295	COG3949	Membrane
B7470_RS19300	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
B7470_RS19305	COG0720	synthase
B7470_RS19310	COG0602	queuosine metabolic process
B7470_RS19315	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
B7470_RS19325	COG4873	Protein conserved in bacteria
B7470_RS19335	COG3773	Cell wall hydrolase
B7470_RS19340	COG2244	polysaccharide biosynthetic process
B7470_RS19345	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B7470_RS19350	COG2217	Heavy metal translocating P-type atpase
B7470_RS19360	COG0006	proline dipeptidase activity
B7470_RS19365	COG1609	Transcriptional regulator
B7470_RS19370	COG3711	transcriptional antiterminator
B7470_RS19375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B7470_RS19375	COG2190	(PTS) system
B7470_RS19375	COG1263	PTS System
B7470_RS19380	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7470_RS19385	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B7470_RS19395	COG1533	DNA photolyase activity
B7470_RS19400	COG0456	acetyltransferase
B7470_RS19405	COG0840	transmembrane signaling receptor activity
B7470_RS19410	COG2084	Dehydrogenase
B7470_RS19415	COG3328	transposase activity
B7470_RS19420	COG2340	Cysteine-rich secretory protein family
B7470_RS19425	COG0768	penicillin binding
B7470_RS19430	COG4191	Histidine kinase
B7470_RS19435	COG0436	Aminotransferase
B7470_RS19445	COG0784	Response regulator, receiver
B7470_RS19445	COG0835	chemotaxis
B7470_RS19455	COG2814	Major facilitator Superfamily
B7470_RS19460	COG1376	ErfK ybiS ycfS ynhG family protein
B7470_RS19465	COG1408	metallophosphoesterase
B7470_RS19470	COG1028	Short-chain dehydrogenase reductase Sdr
B7470_RS19475	COG2200	EAL domain
B7470_RS19480	COG4703	Protein of unknown function (DUF1797)
B7470_RS19485	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
B7470_RS19495	COG0517	IMP dehydrogenase activity
B7470_RS19500	COG0583	DNA-binding transcription factor activity
B7470_RS19505	COG0716	FMN binding
B7470_RS19515	COG0716	FMN binding
B7470_RS19520	COG2171	N-acyltransferase activity
B7470_RS19525	COG1473	amidohydrolase
B7470_RS19535	COG0668	transmembrane transport
B7470_RS19540	COG0450	alkyl hydroperoxide reductase
B7470_RS19545	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B7470_RS19565	COG0746	molybdenum cofactor guanylyltransferase activity
B7470_RS19570	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B7470_RS19575	COG0303	'Molybdopterin
B7470_RS19580	COG1763	Mo-molybdopterin cofactor biosynthetic process
B7470_RS19585	COG0314	molybdopterin synthase activity
B7470_RS19590	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
B7470_RS19600	COG1132	(ABC) transporter
B7470_RS19610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7470_RS19615	COG1136	(ABC) transporter
B7470_RS19620	COG0577	efflux transmembrane transporter activity
B7470_RS19625	COG1349	DNA-binding transcription factor activity
B7470_RS19630	COG1105	Belongs to the carbohydrate kinase PfkB family
B7470_RS19635	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B7470_RS19635	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B7470_RS19635	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7470_RS19640	COG0681	Belongs to the peptidase S26 family
B7470_RS19650	COG0488	(ABC) transporter
B7470_RS19655	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
B7470_RS19660	COG2309	aminopeptidase activity
B7470_RS19670	COG1077	Cell shape determining protein MreB Mrl
B7470_RS19675	COG2002	toxin-antitoxin pair type II binding
B7470_RS19680	COG3852	Histidine kinase
B7470_RS19685	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
B7470_RS19685	COG2105	PFAM AIG2 family protein
B7470_RS19690	COG0569	domain protein
B7470_RS19695	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
B7470_RS19700	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
B7470_RS19710	COG0561	phosphatase activity
B7470_RS19715	COG0242	peptide deformylase activity
B7470_RS19730	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B7470_RS19735	COG0022	dehydrogenase e1 component
B7470_RS19740	COG0508	dehydrogenase complex catalyzes the overall conversion of
B7470_RS19745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B7470_RS19750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B7470_RS19760	COG1982	Orn Lys Arg decarboxylase major
B7470_RS19765	COG4476	Belongs to the UPF0223 family
B7470_RS19770	COG4493	Belongs to the UPF0637 family
B7470_RS19780	COG0483	inositol monophosphate 1-phosphatase activity
B7470_RS19795	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
B7470_RS19850	COG4896	Protein conserved in bacteria
B7470_RS19860	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
B7470_RS19865	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
B7470_RS19870	COG2066	Belongs to the glutaminase family
B7470_RS19875	COG4838	Belongs to the UPF0358 family
B7470_RS19880	COG0772	Belongs to the SEDS family
B7470_RS19885	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
B7470_RS19890	COG1612	heme a metabolic process
B7470_RS19895	COG0109	protoheme IX farnesyltransferase activity
B7470_RS19900	COG2010	Cytochrome c
B7470_RS19900	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
B7470_RS19905	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B7470_RS19910	COG1845	cytochrome c oxidase, subunit III
B7470_RS19915	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
B7470_RS19920	COG3336	cytochrome c oxidase
B7470_RS19930	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
B7470_RS19935	COG2340	Cysteine-rich secretory protein family
B7470_RS19950	COG3679	Belongs to the UPF0342 family
B7470_RS19955	COG4471	UPF0298 protein
B7470_RS19960	COG0742	ribosomal rna small subunit methyltransferase
B7470_RS19965	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
B7470_RS19970	COG3314	Sporulation integral membrane protein YlbJ
B7470_RS19975	COG1752	Esterase of the alpha-beta hydrolase superfamily
B7470_RS19980	COG3480	Lon protease (S16) C-terminal proteolytic domain
B7470_RS19985	COG1323	Belongs to the UPF0348 family
B7470_RS19995	COG1399	metal-binding, possibly nucleic acid-binding protein
B7470_RS20010	COG0454	-acetyltransferase
B7470_RS20015	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
B7470_RS20020	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
B7470_RS20025	COG2001	Belongs to the MraZ family
B7470_RS20030	COG0275	rRNA processing
B7470_RS20035	COG4839	cell division protein FtsL
B7470_RS20045	COG0768	penicillin binding
B7470_RS20050	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
B7470_RS20055	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B7470_RS20060	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
B7470_RS20065	COG0772	Belongs to the SEDS family
B7470_RS20070	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B7470_RS20075	COG0812	UDP-N-acetylmuramate dehydrogenase activity
B7470_RS20080	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
B7470_RS20085	COG3879	Bacterial protein of unknown function (DUF881)
B7470_RS20090	COG3879	Bacterial protein of unknown function (DUF881)
B7470_RS20095	COG3856	small basic protein
B7470_RS20100	COG0849	cell division
B7470_RS20105	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
B7470_RS20110	COG4412	M6 family metalloprotease domain protein
B7470_RS20110	COG1404	Belongs to the peptidase S8 family
B7470_RS20120	COG1191	sigma factor activity
B7470_RS20125	COG1191	sigma factor activity
B7470_RS20130	COG1119	ATPase activity
B7470_RS20135	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B7470_RS20140	COG1873	PFAM PRC-barrel domain
B7470_RS20150	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
B7470_RS20155	COG1799	cell septum assembly
B7470_RS20160	COG0762	integral membrane protein
B7470_RS20165	COG2302	S4 RNA-binding domain
B7470_RS20170	COG3599	regulation of cell shape
B7470_RS20175	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
B7470_RS20180	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B7470_RS20185	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
B7470_RS20190	COG0564	pseudouridine synthase activity
B7470_RS20195	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
B7470_RS20200	COG2233	PERMEase
B7470_RS20205	COG0540	Belongs to the ATCase OTCase family
B7470_RS20210	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B7470_RS20215	COG0505	Belongs to the CarA family
B7470_RS20220	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B7470_RS20225	COG0543	2 iron, 2 sulfur cluster binding
B7470_RS20230	COG0167	dihydroorotate dehydrogenase activity
B7470_RS20235	COG0284	orotidine-5'-phosphate decarboxylase activity
B7470_RS20240	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
B7470_RS20245	COG0175	sulfate reduction
B7470_RS20250	COG0306	phosphate transporter
B7470_RS20255	COG2046	Belongs to the sulfate adenylyltransferase family
B7470_RS20260	COG0529	Catalyzes the synthesis of activated sulfate
B7470_RS20265	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B7470_RS20270	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
B7470_RS20275	COG1648	precorrin-2 dehydrogenase activity
B7470_RS20285	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
B7470_RS20290	COG1561	YicC-like family, N-terminal region
B7470_RS20300	COG0194	GDP metabolic process
B7470_RS20305	COG1758	RNA polymerase activity
B7470_RS20310	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B7470_RS20315	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
B7470_RS20320	COG0242	peptide deformylase activity
B7470_RS20325	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
B7470_RS20330	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
B7470_RS20330	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B7470_RS20335	COG0820	rRNA (adenine-C2-)-methyltransferase activity
B7470_RS20340	COG0631	protein serine/threonine phosphatase activity
B7470_RS20345	COG0515	serine threonine protein kinase
B7470_RS20345	COG2815	serine threonine protein kinase
B7470_RS20350	COG1162	GTPase activity
B7470_RS20355	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B7470_RS20360	COG1564	THIamine pyrophosphokinase
B7470_RS20370	COG0227	Belongs to the bacterial ribosomal protein bL28 family
B7470_RS20375	COG1302	Protein conserved in bacteria
B7470_RS20380	COG1461	Dihydroxyacetone kinase
B7470_RS20385	COG1760	l-serine dehydratase
B7470_RS20390	COG1760	l-serine dehydratase
B7470_RS20395	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
B7470_RS20400	COG1349	DNA-binding transcription factor activity
B7470_RS20400	COG2050	protein possibly involved in aromatic compounds catabolism
B7470_RS20405	COG0416	fatty acid biosynthetic process
B7470_RS20410	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
B7470_RS20415	COG1028	Short-chain dehydrogenase reductase Sdr
B7470_RS20425	COG0571	ribonuclease III activity
B7470_RS20430	COG1196	nuclear chromosome segregation
B7470_RS20435	COG0552	protein localization to endoplasmic reticulum
B7470_RS20445	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
B7470_RS20450	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
B7470_RS20455	COG0228	four-way junction DNA binding
B7470_RS20460	COG1837	Belongs to the UPF0109 family
B7470_RS20470	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
B7470_RS20475	COG0336	Belongs to the RNA methyltransferase TrmD family
B7470_RS20480	COG0335	large ribosomal subunit rRNA binding
B7470_RS20485	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
B7470_RS20490	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
B7470_RS20500	COG2257	FlhB HrpN YscU SpaS Family
B7470_RS20505	COG0045	succinate-CoA ligase (ADP-forming) activity
B7470_RS20510	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
B7470_RS20515	COG0758	DNA mediated transformation
B7470_RS20520	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B7470_RS20525	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
B7470_RS20530	COG4974	Belongs to the 'phage' integrase family
B7470_RS20535	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
B7470_RS20540	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
B7470_RS20545	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
B7470_RS20550	COG1815	bacterial-type flagellum-dependent cell motility
B7470_RS20555	COG1558	bacterial-type flagellum-dependent cell motility
B7470_RS20560	COG1677	Flagellar hook-basal body complex protein FliE
B7470_RS20570	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B7470_RS20575	COG1317	bacterial-type flagellum organization
B7470_RS20580	COG1157	protein secretion by the type III secretion system
B7470_RS20585	COG2882	bacterial-type flagellum organization
B7470_RS20590	COG3334	PFAM MgtE intracellular
B7470_RS20595	COG3144	bacterial-type flagellum assembly
B7470_RS20600	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
B7470_RS20605	COG4786	Flagellar basal body rod
B7470_RS20610	COG1582	Flagellar protein (FlbD)
B7470_RS20615	COG1580	Controls the rotational direction of flagella during chemotaxis
B7470_RS20620	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B7470_RS20625	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B7470_RS20625	COG1776	CheC inhibitor of MCP methylation
B7470_RS20630	COG2201	protein-glutamate methylesterase activity
B7470_RS20635	COG3190	flagellar
B7470_RS20640	COG1338	Plays a role in the flagellum-specific transport system
B7470_RS20645	COG1987	bacterial-type flagellum assembly
B7470_RS20650	COG1684	flagellar biosynthetic protein fliR
B7470_RS20655	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B7470_RS20660	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B7470_RS20665	COG1419	protein localization to endoplasmic reticulum
B7470_RS20670	COG0455	bacterial-type flagellum organization
B7470_RS20675	COG2201	protein-glutamate methylesterase activity
B7470_RS20680	COG0643	Histidine kinase
B7470_RS20680	COG2198	Histidine kinase
B7470_RS20685	COG0835	chemotaxis
B7470_RS20695	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
B7470_RS20700	COG1191	sigma factor activity
B7470_RS20710	COG0052	Belongs to the universal ribosomal protein uS2 family
B7470_RS20715	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
B7470_RS20720	COG0528	UMP kinase activity
B7470_RS20725	COG0233	cytoplasmic translational termination
B7470_RS20730	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
B7470_RS20735	COG4589	Belongs to the CDS family
B7470_RS20740	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
B7470_RS20745	COG0750	zinc metalloprotease
B7470_RS20750	COG0442	prolyl-tRNA aminoacylation
B7470_RS20755	COG2176	DNA-directed DNA polymerase activity
B7470_RS20760	COG0779	Required for maturation of 30S ribosomal subunits
B7470_RS20765	COG0195	Participates in both transcription termination and antitermination
B7470_RS20770	COG2740	Nucleic-acid-binding protein implicated in transcription termination
B7470_RS20775	COG1358	cellular component organization or biogenesis
B7470_RS20780	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
B7470_RS20785	COG1550	Protein conserved in bacteria
B7470_RS20790	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
B7470_RS20795	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
B7470_RS20800	COG0196	riboflavin kinase activity
B7470_RS20805	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
B7470_RS20810	COG1185	polyribonucleotide nucleotidyltransferase activity
B7470_RS20815	COG0726	polysaccharide deacetylase
B7470_RS20820	COG0612	Peptidase, M16
B7470_RS20825	COG1873	PFAM PRC-barrel domain
B7470_RS20830	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B7470_RS20835	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B7470_RS20840	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
B7470_RS20845	COG0527	aspartate kinase activity
B7470_RS20850	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B7470_RS20855	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
B7470_RS20860	COG0740	serine-type endopeptidase activity
B7470_RS20870	COG4980	gas vesicle protein
B7470_RS20870	COG1674	ftsk spoiiie
B7470_RS20875	COG2188	Transcriptional regulator
B7470_RS20880	COG2814	Major facilitator Superfamily
B7470_RS20885	COG0612	Peptidase, M16
B7470_RS20890	COG0612	Peptidase, M16
B7470_RS20895	COG0300	oxidoreductase activity
B7470_RS20910	COG1426	Protein conserved in bacteria
B7470_RS20915	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B7470_RS20920	COG1058	Belongs to the CinA family
B7470_RS20920	COG1546	Belongs to the CinA family
B7470_RS20925	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
B7470_RS20930	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B7470_RS20935	COG1418	mRNA catabolic process
B7470_RS20940	COG1692	metallophosphoesterase
B7470_RS20945	COG2359	stage V sporulation protein S
B7470_RS20950	COG1063	alcohol dehydrogenase
B7470_RS20955	COG0156	8-amino-7-oxononanoate synthase activity
B7470_RS20960	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B7470_RS20965	COG4550	Control of competence regulator ComK, YlbF/YmcA
B7470_RS20975	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
B7470_RS20980	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
B7470_RS21060	COG3328	transposase activity
B7470_RS21080	COG3226	Transcriptional regulator
B7470_RS21090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B7470_RS21095	COG1404	Belongs to the peptidase S8 family
B7470_RS21105	COG4195	phage-related replication protein
B7470_RS21110	COG1764	response to oxidative stress
B7470_RS21115	COG2076	Multidrug Resistance protein
B7470_RS21120	COG2076	Multidrug Resistance protein
B7470_RS21135	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
B7470_RS21140	COG1923	regulation of RNA biosynthetic process
B7470_RS21155	COG1780	Probably involved in ribonucleotide reductase function
B7470_RS21160	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B7470_RS21165	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B7470_RS21170	COG4112	unkown
B7470_RS21175	COG0860	N-Acetylmuramoyl-L-alanine amidase
B7470_RS21185	COG0464	growth
B7470_RS21190	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B7470_RS21195	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
B7470_RS21200	COG0789	Transcriptional regulator
B7470_RS21205	COG0174	glutamine synthetase
B7470_RS21210	COG4974	Belongs to the 'phage' integrase family
B7470_RS21230	COG3645	SOS response
B7470_RS21230	COG3646	Phage regulatory protein
B7470_RS21375	COG5412	phage tail tape measure protein
B7470_RS21375	COG3953	SLT domain
B7470_RS21420	COG5632	N-Acetylmuramoyl-L-alanine amidase
B7470_RS21420	COG3409	Peptidoglycan-binding domain 1 protein
B7470_RS21420	COG1388	LysM domain
B7470_RS21430	COG5444	nuclease activity
B7470_RS21470	COG4282	regulation of fungal-type cell wall biogenesis
B7470_RS21490	COG3328	transposase activity
B7470_RS21505	COG3655	Transcriptional regulator
B7470_RS21530	COG0135	phosphoribosylanthranilate isomerase activity
B7470_RS21535	COG2211	Major facilitator Superfamily
B7470_RS21550	COG3507	Belongs to the glycosyl hydrolase 43 family
B7470_RS21555	COG1940	carbohydrate kinase activity
B7470_RS21560	COG2115	Belongs to the xylose isomerase family
B7470_RS21565	COG1070	Carbohydrate kinase
B7470_RS21575	COG3328	transposase activity
B7470_RS21580	COG1525	nuclease
B7470_RS21585	COG2814	Major facilitator Superfamily
B7470_RS21590	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B7470_RS21605	COG0756	dUTP diphosphatase activity
B7470_RS21645	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B7470_RS21660	COG3832	glyoxalase III activity
B7470_RS21705	COG4195	phage-related replication protein
B7470_RS21715	COG0346	lactoylglutathione lyase activity
B7470_RS21725	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B7470_RS21730	COG1388	LysM domain
B7470_RS21735	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
B7470_RS21740	COG4224	UPF0291 protein
B7470_RS21745	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
B7470_RS21755	COG3763	UPF0154 protein
B7470_RS21765	COG0785	Cytochrome C biogenesis protein
B7470_RS21770	COG2201	protein-glutamate methylesterase activity
B7470_RS21775	COG4846	Membrane protein involved in cytochrome C biogenesis
B7470_RS21785	COG0071	Belongs to the small heat shock protein (HSP20) family
B7470_RS21800	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
B7470_RS21805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B7470_RS21825	COG0824	Thioesterase
B7470_RS21835	COG4841	protein insertion into membrane
B7470_RS21840	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
B7470_RS21845	COG1832	CoA-binding protein
B7470_RS21850	COG0187	DNA topoisomerase II activity
B7470_RS21855	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B7470_RS21865	COG1115	amino acid carrier protein
B7470_RS21870	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
B7470_RS21880	COG5520	Belongs to the glycosyl hydrolase 30 family
B7470_RS21890	COG2246	polysaccharide biosynthetic process
B7470_RS21895	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B7470_RS21900	COG0586	Pfam SNARE associated Golgi protein
B7470_RS21905	COG2404	hydrolase activity, acting on ester bonds
B7470_RS21910	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B7470_RS21915	COG1024	Enoyl-CoA hydratase
B7470_RS21920	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B7470_RS21925	COG0511	ligase activity, forming carbon-carbon bonds
B7470_RS21930	COG0439	Biotin carboxylase
B7470_RS21935	COG0318	PFAM AMP-dependent synthetase and ligase
B7470_RS21940	COG1960	acyl-CoA dehydrogenase activity
B7470_RS21950	COG1649	PFAM Uncharacterised BCR, COG1649
B7470_RS21965	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7470_RS22035	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B7470_RS22040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family