locus-tag	class	description
KO64_RS00015	COG0592	DNA-directed DNA polymerase activity
KO64_RS00020	COG2501	S4 domain
KO64_RS00035	COG0187	DNA topoisomerase II activity
KO64_RS00040	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KO64_RS00075	COG0517	IMP dehydrogenase activity
KO64_RS00075	COG0516	GMP reductase activity
KO64_RS00080	COG1686	Belongs to the peptidase S11 family
KO64_RS00100	COG1929	Belongs to the glycerate kinase type-1 family
KO64_RS00110	COG1428	Deoxynucleoside kinase
KO64_RS00115	COG1428	Deoxynucleoside kinase
KO64_RS00120	COG3858	chitin binding
KO64_RS00120	COG1388	LysM domain
KO64_RS00125	COG1335	isochorismatase
KO64_RS00130	COG0590	tRNA wobble adenosine to inosine editing
KO64_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KO64_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KO64_RS00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
KO64_RS00195	COG3853	Toxic anion resistance protein (TelA)
KO64_RS00200	COG1982	Orn Lys Arg decarboxylase major
KO64_RS00210	COG3870	Protein conserved in bacteria
KO64_RS00215	COG1728	Protein conserved in bacteria
KO64_RS00220	COG0470	DNA polymerase III
KO64_RS00225	COG1774	PSP1 C-terminal conserved region
KO64_RS00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KO64_RS00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KO64_RS00250	COG2002	toxin-antitoxin pair type II binding
KO64_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KO64_RS00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KO64_RS00260	COG0084	hydrolase, TatD family'
KO64_RS00265	COG3583	domain protein
KO64_RS00265	COG3584	3D domain protein
KO64_RS00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KO64_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KO64_RS00285	COG4466	Protein conserved in bacteria
KO64_RS00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KO64_RS00305	COG0251	oxidation-reduction process
KO64_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KO64_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KO64_RS00345	COG2002	toxin-antitoxin pair type II binding
KO64_RS00350	COG2244	polysaccharide biosynthetic process
KO64_RS00355	COG3956	TIGRFAM MazG family protein
KO64_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KO64_RS00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KO64_RS00380	COG1098	S1 RNA binding domain
KO64_RS00395	COG2208	phosphoserine phosphatase activity
KO64_RS00400	COG2304	oxidoreductase activity
KO64_RS00405	COG0515	serine threonine protein kinase
KO64_RS00410	COG0037	tRNA processing
KO64_RS00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KO64_RS00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KO64_RS00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KO64_RS00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KO64_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KO64_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
KO64_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KO64_RS00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KO64_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KO64_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KO64_RS00475	COG1396	sequence-specific DNA binding
KO64_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KO64_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KO64_RS00570	COG4463	regulation of RNA biosynthetic process
KO64_RS00575	COG3880	PFAM UvrB UvrC protein
KO64_RS00585	COG0542	response to heat
KO64_RS00590	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KO64_RS00595	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
KO64_RS00600	COG4956	integral membrane protein (PIN domain superfamily)
KO64_RS00620	COG1045	serine acetyltransferase
KO64_RS00630	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KO64_RS00635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KO64_RS00640	COG3688	RNA-binding protein containing a PIN domain
KO64_RS00645	COG1595	DNA-templated transcription, initiation
KO64_RS00655	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KO64_RS00660	COG0250	Participates in transcription elongation, termination and antitermination
KO64_RS00685	COG2813	Specifically methylates the guanine in position
KO64_RS00700	COG1358	cellular component organization or biogenesis
KO64_RS00725	COG0596	Alpha beta hydrolase
KO64_RS00830	COG0201	protein transport
KO64_RS00840	COG0024	Methionine aminopeptidase
KO64_RS00850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KO64_RS00875	COG1122	ATPase activity
KO64_RS00880	COG1122	ATPase activity
KO64_RS00885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KO64_RS00905	COG2226	methyltransferase
KO64_RS00910	COG2318	DinB family
KO64_RS00920	COG0860	N-Acetylmuramoyl-L-alanine amidase
KO64_RS00925	COG0489	protein tyrosine kinase activity
KO64_RS00935	COG2194	sulfuric ester hydrolase activity
KO64_RS00940	COG0726	polysaccharide deacetylase
KO64_RS01000	COG0738	Major facilitator superfamily
KO64_RS01005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KO64_RS01020	COG0659	secondary active sulfate transmembrane transporter activity
KO64_RS01025	COG0385	Bile acid
KO64_RS01030	COG2819	hydrolase of the alpha beta superfamily
KO64_RS01035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KO64_RS01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KO64_RS01045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KO64_RS01050	COG2207	Transcriptional regulator
KO64_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KO64_RS01055	COG3876	Protein conserved in bacteria
KO64_RS01060	COG1472	Belongs to the glycosyl hydrolase 3 family
KO64_RS01065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KO64_RS01070	COG1263	PTS System
KO64_RS01070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KO64_RS01080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KO64_RS01085	COG1683	Conserved Protein
KO64_RS01115	COG1595	DNA-templated transcription, initiation
KO64_RS01120	COG5662	AntiSigma factor
KO64_RS01125	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KO64_RS01130	COG4856	YbbR-like protein
KO64_RS01180	COG2205	protein histidine kinase activity
KO64_RS01185	COG1136	(ABC) transporter
KO64_RS01190	COG0577	efflux transmembrane transporter activity
KO64_RS01195	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KO64_RS01210	COG1346	cytolysis
KO64_RS01215	COG1380	Effector of murein hydrolase LrgA
KO64_RS01220	COG1846	Transcriptional regulator
KO64_RS01225	COG1113	amino acid transport
KO64_RS01230	COG1011	Hydrolase
KO64_RS01235	COG4585	Histidine kinase
KO64_RS01240	COG2197	response regulator
KO64_RS01245	COG1131	(ABC) transporter
KO64_RS01285	COG0531	amino acid
KO64_RS01290	COG0584	glycerophosphoryl diester phosphodiesterase
KO64_RS01295	COG2271	Major facilitator Superfamily
KO64_RS01305	COG2368	4-hydroxyphenylacetate
KO64_RS01315	COG3409	Peptidoglycan-binding domain 1 protein
KO64_RS01330	COG0371	Dehydrogenase
KO64_RS01340	COG1183	phosphatidylcholine synthase activity
KO64_RS01345	COG0586	Pfam SNARE associated Golgi protein
KO64_RS01350	COG0688	phosphatidylethanolamine metabolic process
KO64_RS01365	COG1301	dicarboxylic acid transport
KO64_RS01370	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KO64_RS01375	COG0833	amino acid
KO64_RS01380	COG2040	homocysteine
KO64_RS01385	COG1115	amino acid carrier protein
KO64_RS01390	COG2066	Belongs to the glutaminase family
KO64_RS01395	COG4191	Histidine kinase
KO64_RS01400	COG0784	Response regulator, receiver
KO64_RS01415	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KO64_RS01420	COG0778	Nitroreductase
KO64_RS01425	COG0346	lactoylglutathione lyase activity
KO64_RS01430	COG2259	Doxx family
KO64_RS01435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KO64_RS01445	COG3773	Cell wall hydrolase
KO64_RS01450	COG3540	Alkaline phosphatase
KO64_RS01455	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KO64_RS01460	COG0805	protein transport
KO64_RS01470	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KO64_RS01475	COG0477	Major facilitator Superfamily
KO64_RS01480	COG1309	transcriptional regulator
KO64_RS01485	COG0252	asparaginase activity
KO64_RS01490	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KO64_RS01495	COG1405	negative regulation of cell septum assembly
KO64_RS01495	COG3012	SEC-C Motif Domain Protein
KO64_RS01500	COG0667	Aldo Keto reductase
KO64_RS01510	COG1595	DNA-templated transcription, initiation
KO64_RS01515	COG1595	DNA-templated transcription, initiation
KO64_RS01520	COG1876	peptidase activity
KO64_RS01525	COG0457	Tetratricopeptide repeat
KO64_RS01530	COG1028	Short-chain dehydrogenase reductase Sdr
KO64_RS01535	COG0366	Alpha amylase catalytic
KO64_RS01540	COG0803	Belongs to the bacterial solute-binding protein 9 family
KO64_RS01545	COG1121	(ABC) transporter
KO64_RS01550	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KO64_RS01555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KO64_RS01560	COG2310	stress, protein
KO64_RS01565	COG2310	stress, protein
KO64_RS01570	COG2310	stress, protein
KO64_RS01575	COG0861	Integral membrane protein TerC family
KO64_RS01585	COG3853	Toxic anion resistance protein (TelA)
KO64_RS01590	COG0477	Major facilitator Superfamily
KO64_RS01595	COG0517	IMP dehydrogenase activity
KO64_RS01595	COG4175	Glycine betaine
KO64_RS01600	COG4176	ABC-type proline glycine betaine transport system permease component
KO64_RS01605	COG2113	Glycine betaine
KO64_RS01610	COG1473	amidohydrolase
KO64_RS01615	COG1288	antiporter activity
KO64_RS01625	COG0366	Alpha amylase catalytic
KO64_RS01635	COG2814	Major facilitator Superfamily
KO64_RS01640	COG1846	Transcriptional regulator
KO64_RS01645	COG1280	lysine exporter protein (LysE YggA)
KO64_RS01650	COG3403	YqcI/YcgG family
KO64_RS01655	COG1113	amino acid transport
KO64_RS01660	COG3665	Urea carboxylase-associated protein
KO64_RS01675	COG1660	Displays ATPase and GTPase activities
KO64_RS01680	COG1082	Xylose isomerase domain protein TIM barrel
KO64_RS01685	COG2271	Major facilitator Superfamily
KO64_RS01690	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KO64_RS01700	COG2801	Transposase and inactivated derivatives
KO64_RS01705	COG3458	cephalosporin-C deacetylase activity
KO64_RS01710	COG3541	Predicted nucleotidyltransferase
KO64_RS01715	COG0506	proline dehydrogenase activity
KO64_RS01720	COG1012	belongs to the aldehyde dehydrogenase family
KO64_RS01725	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KO64_RS01730	COG2508	Transcriptional regulator
KO64_RS01740	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KO64_RS01740	COG1587	Uroporphyrinogen-III synthase
KO64_RS01745	COG2146	nitrite reductase [NAD(P)H] activity
KO64_RS01750	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KO64_RS01755	COG0243	molybdopterin cofactor binding
KO64_RS01760	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KO64_RS01765	COG2223	nitrite transmembrane transporter activity
KO64_RS01770	COG0523	cobalamin synthesis protein
KO64_RS01775	COG1063	alcohol dehydrogenase
KO64_RS01780	COG1714	RDD family
KO64_RS01790	COG2723	6-phospho-beta-galactosidase activity
KO64_RS01800	COG3209	COG3209 Rhs family protein
KO64_RS01805	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KO64_RS01810	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
KO64_RS01815	COG1733	regulation of RNA biosynthetic process
KO64_RS01825	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KO64_RS01830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KO64_RS01835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KO64_RS01840	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
KO64_RS01855	COG0697	spore germination
KO64_RS01860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KO64_RS01870	COG2364	Membrane
KO64_RS01875	COG1126	abc transporter atp-binding protein
KO64_RS01880	COG0765	amino acid transport
KO64_RS01885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KO64_RS01890	COG0583	DNA-binding transcription factor activity
KO64_RS01895	COG0163	prenyltransferase activity
KO64_RS01900	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KO64_RS01915	COG3104	oligopeptide transport
KO64_RS01920	COG5434	Belongs to the glycosyl hydrolase 28 family
KO64_RS01930	COG0697	spore germination
KO64_RS01940	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KO64_RS01945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KO64_RS01950	COG0456	acetyltransferase
KO64_RS01955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KO64_RS01960	COG0765	amino acid transport
KO64_RS01965	COG1126	abc transporter atp-binding protein
KO64_RS01970	COG1473	amidohydrolase
KO64_RS01975	COG2079	MmgE PrpD family protein
KO64_RS01980	COG1136	(ABC) transporter
KO64_RS01985	COG0577	efflux transmembrane transporter activity
KO64_RS01990	COG0745	RESPONSE REGULATOR receiver
KO64_RS01995	COG5002	protein histidine kinase activity
KO64_RS01995	COG3850	Histidine kinase
KO64_RS02000	COG0457	Tetratricopeptide repeat
KO64_RS02010	COG0527	aspartate kinase activity
KO64_RS02015	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KO64_RS02020	COG4605	iron ion homeostasis
KO64_RS02025	COG4604	ABC transporter, ATP-binding protein
KO64_RS02030	COG4607	ABC-type enterochelin transport system periplasmic component
KO64_RS02035	COG2814	Major facilitator Superfamily
KO64_RS02040	COG1309	transcriptional regulator
KO64_RS02045	COG0778	Nitroreductase
KO64_RS02050	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KO64_RS02055	COG0640	Transcriptional regulator
KO64_RS02060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KO64_RS02065	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KO64_RS02070	COG1012	belongs to the aldehyde dehydrogenase family
KO64_RS02075	COG4975	Glucose uptake
KO64_RS02080	COG1028	Short-chain dehydrogenase reductase Sdr
KO64_RS02085	COG4549	nuclear export factor GLE1
KO64_RS02090	COG2372	response to copper ion
KO64_RS02090	COG1276	copper resistance
KO64_RS02095	COG1349	DNA-binding transcription factor activity
KO64_RS02105	COG2213	PTS system mannitol-specific
KO64_RS02110	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KO64_RS02120	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KO64_RS02125	COG0561	phosphatase activity
KO64_RS02135	COG1914	H( )-stimulated, divalent metal cation uptake system
KO64_RS02145	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KO64_RS02150	COG1984	allophanate hydrolase subunit 2
KO64_RS02155	COG1414	Transcriptional regulator
KO64_RS02160	COG2755	lipolytic protein G-D-S-L family
KO64_RS02170	COG2329	Antibiotic biosynthesis monooxygenase
KO64_RS02175	COG0768	penicillin binding
KO64_RS02180	COG4989	oxidoreductase activity
KO64_RS02185	COG3711	transcriptional antiterminator
KO64_RS02190	COG0318	PFAM AMP-dependent synthetase and ligase
KO64_RS02195	COG1028	Short-chain dehydrogenase reductase Sdr
KO64_RS02200	COG1917	Cupin 2, conserved barrel domain protein
KO64_RS02205	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KO64_RS02210	COG3871	stress protein (general stress protein 26)
KO64_RS02225	COG2801	Transposase and inactivated derivatives
KO64_RS02230	COG2814	Major facilitator Superfamily
KO64_RS02235	COG1522	sequence-specific DNA binding
KO64_RS02240	COG0551	DNA topoisomerase type I activity
KO64_RS02240	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KO64_RS02245	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KO64_RS02250	COG3706	GGDEF domain
KO64_RS02255	COG5298	Protein conserved in bacteria
KO64_RS02260	COG1215	transferase activity, transferring glycosyl groups
KO64_RS02270	COG0531	amino acid
KO64_RS02275	COG0494	nUDIX hydrolase
KO64_RS02280	COG0028	Belongs to the TPP enzyme family
KO64_RS02300	COG1794	racemase activity, acting on amino acids and derivatives
KO64_RS02330	COG1914	H( )-stimulated, divalent metal cation uptake system
KO64_RS02345	COG4876	unkown
KO64_RS02355	COG2076	Multidrug Resistance protein
KO64_RS02360	COG2217	Heavy metal translocating P-type atpase
KO64_RS02365	COG3729	General stress protein
KO64_RS02370	COG0662	Cupin 2, conserved barrel domain protein
KO64_RS02375	COG2329	Antibiotic biosynthesis monooxygenase
KO64_RS02380	COG3546	catalase activity
KO64_RS02385	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KO64_RS02390	COG3290	protein histidine kinase activity
KO64_RS02395	COG4565	transcriptional regulatory protein
KO64_RS02400	COG1301	dicarboxylic acid transport
KO64_RS02405	COG0628	permease
KO64_RS02410	COG1131	(ABC) transporter
KO64_RS02415	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KO64_RS02425	COG1960	acyl-CoA dehydrogenase activity
KO64_RS02435	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KO64_RS02440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KO64_RS02450	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KO64_RS02455	COG0513	Belongs to the DEAD box helicase family
KO64_RS02460	COG3402	PFAM membrane-flanked domain
KO64_RS02465	COG3428	Bacterial PH domain
KO64_RS02470	COG0705	Rhomboid family
KO64_RS02480	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KO64_RS02485	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KO64_RS02490	COG0864	Transcriptional regulator
KO64_RS02495	COG2337	Toxic component of a toxin-antitoxin (TA) module
KO64_RS02500	COG1366	Belongs to the anti-sigma-factor antagonist family
KO64_RS02505	COG1366	Belongs to the anti-sigma-factor antagonist family
KO64_RS02510	COG2172	sigma factor antagonist activity
KO64_RS02515	COG2208	phosphoserine phosphatase activity
KO64_RS02520	COG1366	Belongs to the anti-sigma-factor antagonist family
KO64_RS02530	COG1191	sigma factor activity
KO64_RS02535	COG2208	phosphoserine phosphatase activity
KO64_RS02540	COG2183	response to ionizing radiation
KO64_RS02605	COG1959	2 iron, 2 sulfur cluster binding
KO64_RS02610	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KO64_RS02615	COG2249	NAD(P)H dehydrogenase (quinone) activity
KO64_RS02625	COG0477	Major facilitator Superfamily
KO64_RS02640	COG2030	dehydratase
KO64_RS02650	COG1959	2 iron, 2 sulfur cluster binding
KO64_RS02655	COG2910	NAD(P)H-binding
KO64_RS02660	COG1309	transcriptional regulator
KO64_RS02665	COG0300	oxidoreductase activity
KO64_RS02675	COG3239	Fatty acid desaturase
KO64_RS02680	COG1278	Cold shock
KO64_RS02685	COG1329	Transcriptional regulator
KO64_RS02690	COG1794	racemase activity, acting on amino acids and derivatives
KO64_RS02705	COG1846	Transcriptional regulator
KO64_RS02705	COG0456	acetyltransferase
KO64_RS02710	COG2271	Major facilitator Superfamily
KO64_RS02715	COG3621	Patatin-like phospholipase
KO64_RS02725	COG0662	Cupin 2, conserved barrel domain protein
KO64_RS02740	COG0277	FAD linked oxidase domain protein
KO64_RS02765	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KO64_RS02800	COG0351	phosphomethylpyrimidine kinase
KO64_RS02810	COG2801	Transposase and inactivated derivatives
KO64_RS02825	COG1064	alcohol dehydrogenase
KO64_RS02830	COG0789	Transcriptional regulator
KO64_RS02840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KO64_RS02855	COG2814	Major facilitator Superfamily
KO64_RS02860	COG1309	transcriptional regulator
KO64_RS02865	COG0697	spore germination
KO64_RS02870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KO64_RS02875	COG5577	PFAM Coat F domain
KO64_RS02885	COG1063	alcohol dehydrogenase
KO64_RS02890	COG5577	PFAM Coat F domain
KO64_RS02905	COG4585	Histidine kinase
KO64_RS02910	COG2197	response regulator
KO64_RS02915	COG2409	Drug exporters of the RND superfamily
KO64_RS02920	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KO64_RS02925	COG0488	(ABC) transporter
KO64_RS02930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KO64_RS02935	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KO64_RS02945	COG2814	Major facilitator Superfamily
KO64_RS02950	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KO64_RS02960	COG0730	response to heat
KO64_RS02965	COG0456	acetyltransferase
KO64_RS02970	COG4978	Transcriptional regulator
KO64_RS02970	COG0789	Transcriptional regulator
KO64_RS02975	COG0697	spore germination
KO64_RS02980	COG1051	belongs to the nudix hydrolase family
KO64_RS02985	COG2226	methyltransferase
KO64_RS02990	COG0473	3-isopropylmalate dehydrogenase activity
KO64_RS02995	COG1802	Transcriptional regulator
KO64_RS03000	COG1819	glycosyl
KO64_RS03015	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KO64_RS03020	COG1388	LysM domain
KO64_RS03025	COG2814	Major facilitator Superfamily
KO64_RS03030	COG2188	Transcriptional regulator
KO64_RS03035	COG2186	Transcriptional regulator
KO64_RS03040	COG2807	transmembrane transport
KO64_RS03045	COG2076	Multidrug Resistance protein
KO64_RS03050	COG2076	Multidrug Resistance protein
KO64_RS03055	COG1309	transcriptional regulator
KO64_RS03060	COG0531	amino acid
KO64_RS03070	COG3832	glyoxalase III activity
KO64_RS03075	COG0604	alcohol dehydrogenase
KO64_RS03080	COG2814	Major facilitator Superfamily
KO64_RS03120	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KO64_RS03125	COG0802	atpase or kinase
KO64_RS03130	COG1214	PFAM Peptidase M22, glycoprotease
KO64_RS03135	COG0456	acetyltransferase
KO64_RS03140	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KO64_RS03145	COG0488	(ABC) transporter
KO64_RS03160	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KO64_RS03165	COG0805	protein transport
KO64_RS03175	COG1266	CAAX protease self-immunity
KO64_RS03190	COG3409	Peptidoglycan-binding domain 1 protein
KO64_RS03210	COG1063	alcohol dehydrogenase
KO64_RS03215	COG2211	Major facilitator Superfamily
KO64_RS03220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KO64_RS03230	COG1842	Phage shock protein A
KO64_RS03235	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KO64_RS03240	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
KO64_RS03245	COG4260	virion core protein, lumpy skin disease virus
KO64_RS03250	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KO64_RS03250	COG2755	lipolytic protein G-D-S-L family
KO64_RS03260	COG1595	DNA-templated transcription, initiation
KO64_RS03265	COG1063	alcohol dehydrogenase
KO64_RS03270	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KO64_RS03275	COG0823	Involved in the tonB-independent uptake of proteins
KO64_RS03290	COG2132	Multicopper oxidase
KO64_RS03295	COG1113	amino acid transport
KO64_RS03300	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KO64_RS03305	COG0714	Associated with various cellular activities
KO64_RS03310	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KO64_RS03315	COG1305	Transglutaminase-like
KO64_RS03340	COG2252	PERMEase
KO64_RS03345	COG3064	Membrane
KO64_RS03365	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KO64_RS03370	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KO64_RS03375	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KO64_RS03380	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KO64_RS03385	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KO64_RS03400	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KO64_RS03410	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KO64_RS03415	COG0138	bifunctional purine biosynthesis protein purh
KO64_RS03420	COG0151	Belongs to the GarS family
KO64_RS03430	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KO64_RS03435	COG1470	cell adhesion involved in biofilm formation
KO64_RS03440	COG4496	protein, YerC YecD
KO64_RS03445	COG0069	glutamate synthase activity
KO64_RS03460	COG0210	DNA helicase
KO64_RS03470	COG4851	CamS sex pheromone cAM373 precursor
KO64_RS03475	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KO64_RS03480	COG1285	pathogenesis
KO64_RS03485	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KO64_RS03505	COG1309	transcriptional regulator
KO64_RS03510	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KO64_RS03515	COG1597	lipid kinase activity
KO64_RS03520	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KO64_RS03525	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KO64_RS03535	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KO64_RS03570	COG5444	nuclease activity
KO64_RS03600	COG3546	catalase activity
KO64_RS03605	COG0454	-acetyltransferase
KO64_RS03615	COG2323	membrane
KO64_RS03620	COG2329	Antibiotic biosynthesis monooxygenase
KO64_RS03625	COG0346	lactoylglutathione lyase activity
KO64_RS03630	COG1366	Belongs to the anti-sigma-factor antagonist family
KO64_RS03635	COG0196	riboflavin kinase activity
KO64_RS03640	COG0670	Belongs to the BI1 family
KO64_RS03645	COG1846	Transcriptional regulator
KO64_RS03650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KO64_RS03660	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KO64_RS03660	COG2124	cytochrome p450
KO64_RS03665	COG1368	sulfuric ester hydrolase activity
KO64_RS03670	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KO64_RS03675	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KO64_RS03680	COG1442	glycosyl transferase family 8
KO64_RS03685	COG1216	Glycosyl transferase, family 2
KO64_RS03690	COG1442	glycosyl transferase family 8
KO64_RS03695	COG2223	nitrite transmembrane transporter activity
KO64_RS03700	COG0531	amino acid
KO64_RS03705	COG1012	belongs to the aldehyde dehydrogenase family
KO64_RS03710	COG0840	transmembrane signaling receptor activity
KO64_RS03715	COG1028	Short-chain dehydrogenase reductase Sdr
KO64_RS03720	COG0457	Tetratricopeptide repeat
KO64_RS03720	COG0463	Glycosyl transferase, family 2
KO64_RS03725	COG0488	(ABC) transporter
KO64_RS03730	COG0789	Transcriptional regulator
KO64_RS03735	COG2814	Major facilitator Superfamily
KO64_RS03740	COG0488	(ABC) transporter
KO64_RS03745	COG0513	Belongs to the DEAD box helicase family
KO64_RS03750	COG0456	acetyltransferase
KO64_RS03755	COG2130	NADP-dependent
KO64_RS03770	COG3866	Pectate lyase
KO64_RS03775	COG0471	metal ion transport
KO64_RS03800	COG3290	protein histidine kinase activity
KO64_RS03805	COG4565	transcriptional regulatory protein
KO64_RS03810	COG3181	Tripartite tricarboxylate transporter family receptor
KO64_RS03815	COG2851	Citrate transporter
KO64_RS03820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KO64_RS03825	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KO64_RS03835	COG2258	MOSC domain
KO64_RS03845	COG0024	Methionine aminopeptidase
KO64_RS03850	COG1263	PTS System
KO64_RS03850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KO64_RS03860	COG1368	sulfuric ester hydrolase activity
KO64_RS03870	COG0071	Belongs to the small heat shock protein (HSP20) family
KO64_RS03885	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KO64_RS03885	COG1263	PTS System
KO64_RS03890	COG0366	Alpha amylase catalytic
KO64_RS03895	COG2188	Transcriptional regulator
KO64_RS03900	COG0778	Nitroreductase
KO64_RS03915	COG0737	Belongs to the 5'-nucleotidase family
KO64_RS03920	COG0693	protein deglycase activity
KO64_RS03925	COG1609	Transcriptional regulator
KO64_RS03940	COG2814	Major facilitator Superfamily
KO64_RS03950	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KO64_RS03955	COG4980	gas vesicle protein
KO64_RS03960	COG1295	ribonuclease BN
KO64_RS03965	COG0477	Major facilitator Superfamily
KO64_RS03970	COG0387	Pfam Sodium calcium exchanger
KO64_RS03980	COG0668	transmembrane transport
KO64_RS03985	COG0535	radical SAM domain protein
KO64_RS03995	COG0726	polysaccharide deacetylase
KO64_RS04000	COG2084	Dehydrogenase
KO64_RS04010	COG0598	Magnesium transport protein CorA
KO64_RS04015	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KO64_RS04020	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KO64_RS04030	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KO64_RS04035	COG4637	Psort location Cytoplasmic, score
KO64_RS04040	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KO64_RS04045	COG0022	dehydrogenase e1 component
KO64_RS04050	COG0508	dehydrogenase complex catalyzes the overall conversion of
KO64_RS04055	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KO64_RS04060	COG3284	Transcriptional regulator
KO64_RS04070	COG1486	melibiose metabolic process
KO64_RS04075	COG1737	Transcriptional regulator
KO64_RS04080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KO64_RS04080	COG1263	PTS System
KO64_RS04085	COG1132	(ABC) transporter
KO64_RS04090	COG1132	(ABC) transporter
KO64_RS04095	COG2259	Doxx family
KO64_RS04100	COG2514	catechol 2,3-dioxygenase activity
KO64_RS04115	COG1695	Transcriptional regulator
KO64_RS04120	COG2249	NAD(P)H dehydrogenase (quinone) activity
KO64_RS04125	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
KO64_RS04130	COG3848	Pyruvate phosphate dikinase
KO64_RS04130	COG0574	Belongs to the PEP-utilizing enzyme family
KO64_RS04135	COG2732	(Barnase) inhibitor
KO64_RS04140	COG2318	DinB family
KO64_RS04145	COG2814	Major facilitator Superfamily
KO64_RS04150	COG1846	Transcriptional regulator
KO64_RS04155	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KO64_RS04155	COG0392	lysyltransferase activity
KO64_RS04160	COG0384	phenazine biosynthesis protein PhzF
KO64_RS04165	COG0778	Nitroreductase
KO64_RS04175	COG1090	epimerase
KO64_RS04190	COG2814	Major facilitator Superfamily
KO64_RS04200	COG3591	Belongs to the peptidase S1B family
KO64_RS04215	COG3103	Sh3 type 3 domain protein
KO64_RS04220	COG5658	integral membrane protein
KO64_RS04225	COG0596	Alpha beta hydrolase
KO64_RS04230	COG0463	Glycosyl transferase, family 2
KO64_RS04235	COG4485	Bacterial membrane protein, YfhO
KO64_RS04240	COG1988	membrane-bound metal-dependent
KO64_RS04245	COG1194	a g-specific adenine glycosylase
KO64_RS04255	COG1028	Short-chain dehydrogenase reductase Sdr
KO64_RS04275	COG1132	(ABC) transporter
KO64_RS04280	COG4129	membrane
KO64_RS04295	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KO64_RS04300	COG0735	belongs to the Fur family
KO64_RS04410	COG1757	Na H antiporter
KO64_RS04425	COG0277	FAD linked oxidase domain protein
KO64_RS04435	COG0747	negative chemotaxis
KO64_RS04440	COG0601	transmembrane transport
KO64_RS04445	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KO64_RS04450	COG0444	Belongs to the ABC transporter superfamily
KO64_RS04455	COG4608	Belongs to the ABC transporter superfamily
KO64_RS04460	COG0753	catalase activity
KO64_RS04470	COG1116	anion transmembrane transporter activity
KO64_RS04475	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KO64_RS04480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KO64_RS04500	COG1476	TRANSCRIPTIONal
KO64_RS04510	COG3382	B3 4 domain protein
KO64_RS04515	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KO64_RS04525	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KO64_RS04530	COG0789	Transcriptional regulator
KO64_RS04535	COG1664	Polymer-forming cytoskeletal
KO64_RS04540	COG1664	Polymer-forming cytoskeletal
KO64_RS04545	COG2766	serine protein kinase
KO64_RS04555	COG1846	Transcriptional regulator
KO64_RS04560	COG1566	PFAM secretion protein HlyD family protein
KO64_RS04565	COG2814	Major facilitator Superfamily
KO64_RS04570	COG0655	NAD(P)H dehydrogenase (quinone) activity
KO64_RS04585	COG1725	Transcriptional regulator
KO64_RS04590	COG1131	(ABC) transporter
KO64_RS04595	COG1131	(ABC) transporter
KO64_RS04600	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KO64_RS04605	COG1278	Cold shock
KO64_RS04610	COG1464	Belongs to the NlpA lipoprotein family
KO64_RS04615	COG3706	GGDEF domain
KO64_RS04620	COG1823	symporter activity
KO64_RS04640	COG5577	PFAM Coat F domain
KO64_RS04650	COG3764	Sortase (surface protein transpeptidase)
KO64_RS04655	COG0564	pseudouridine synthase activity
KO64_RS04665	COG0517	IMP dehydrogenase activity
KO64_RS04670	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KO64_RS04675	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KO64_RS04675	COG3153	acetyltransferase
KO64_RS04680	COG2801	Transposase and inactivated derivatives
KO64_RS04690	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KO64_RS04695	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KO64_RS04700	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KO64_RS04710	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KO64_RS04715	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KO64_RS04720	COG4585	Histidine kinase
KO64_RS04720	COG2203	Gaf domain
KO64_RS04725	COG2197	response regulator
KO64_RS04730	COG0431	NADPH-dependent FMN reductase
KO64_RS04745	COG0791	NLP P60 protein
KO64_RS04745	COG1388	LysM domain
KO64_RS04750	COG1959	2 iron, 2 sulfur cluster binding
KO64_RS04755	COG0668	transmembrane transport
KO64_RS04760	COG2719	SpoVR family
KO64_RS04765	COG1785	Belongs to the alkaline phosphatase family
KO64_RS04770	COG0791	NLP P60 protein
KO64_RS04770	COG1388	LysM domain
KO64_RS04775	COG0583	DNA-binding transcription factor activity
KO64_RS04780	COG0372	Belongs to the citrate synthase family
KO64_RS04785	COG1028	Short-chain dehydrogenase reductase Sdr
KO64_RS04790	COG0531	amino acid
KO64_RS04795	COG0733	neurotransmitter:sodium symporter activity
KO64_RS04810	COG1595	DNA-templated transcription, initiation
KO64_RS04815	COG0204	Acyl-transferase
KO64_RS04820	COG1253	flavin adenine dinucleotide binding
KO64_RS04825	COG0789	Transcriptional regulator
KO64_RS04830	COG0436	Aminotransferase
KO64_RS04835	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KO64_RS04840	COG1253	flavin adenine dinucleotide binding
KO64_RS04845	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KO64_RS04850	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KO64_RS04855	COG0584	glycerophosphoryl diester phosphodiesterase
KO64_RS04860	COG0668	transmembrane transport
KO64_RS04865	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KO64_RS04870	COG0726	polysaccharide deacetylase
KO64_RS04875	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KO64_RS04880	COG3226	Transcriptional regulator
KO64_RS04890	COG0589	response to stress
KO64_RS04895	COG1132	(ABC) transporter
KO64_RS04900	COG1132	(ABC) transporter
KO64_RS04905	COG0702	epimerase
KO64_RS04920	COG0189	ligase activity
KO64_RS04925	COG0189	ligase activity
KO64_RS04940	COG4335	DNA alkylation repair
KO64_RS04945	COG0561	phosphatase activity
KO64_RS04950	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KO64_RS04960	COG0475	glutathione-regulated potassium exporter activity
KO64_RS04965	COG0490	domain, Protein
KO64_RS04975	COG1024	Enoyl-CoA hydratase
KO64_RS04985	COG4152	abc transporter atp-binding protein
KO64_RS04990	COG1668	transmembrane transport
KO64_RS04995	COG0420	3'-5' exonuclease activity
KO64_RS05000	COG4717	serine-type aminopeptidase activity
KO64_RS05015	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KO64_RS05050	COG4980	gas vesicle protein
KO64_RS05065	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KO64_RS05070	COG0537	adenosine 5'-monophosphoramidase activity
KO64_RS05075	COG1131	(ABC) transporter
KO64_RS05080	COG4473	ABC transporter
KO64_RS05090	COG1473	amidohydrolase
KO64_RS05095	COG3069	C4-dicarboxylate transmembrane transporter activity
KO64_RS05100	COG2329	Antibiotic biosynthesis monooxygenase
KO64_RS05105	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KO64_RS05115	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KO64_RS05120	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KO64_RS05125	COG1309	transcriptional regulator
KO64_RS05130	COG1511	domain protein
KO64_RS05135	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KO64_RS05145	COG1363	Peptidase, m42
KO64_RS05150	COG1301	dicarboxylic acid transport
KO64_RS05155	COG1234	tRNA 3'-trailer cleavage
KO64_RS05160	COG0095	Lipoate-protein ligase
KO64_RS05165	COG0702	epimerase
KO64_RS05170	COG0318	PFAM AMP-dependent synthetase and ligase
KO64_RS05180	COG0501	Belongs to the peptidase M48B family
KO64_RS05185	COG1404	Belongs to the peptidase S8 family
KO64_RS05195	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KO64_RS05200	COG0406	alpha-ribazole phosphatase activity
KO64_RS05205	COG0183	Belongs to the thiolase family
KO64_RS05210	COG0318	PFAM AMP-dependent synthetase and ligase
KO64_RS05215	COG1268	BioY protein
KO64_RS05220	COG0840	transmembrane signaling receptor activity
KO64_RS05225	COG0723	plastoquinol--plastocyanin reductase activity
KO64_RS05225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KO64_RS05230	COG1028	Short-chain dehydrogenase reductase Sdr
KO64_RS05240	COG4903	ComK protein
KO64_RS05250	COG5646	InterPro IPR014922
KO64_RS05275	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KO64_RS05290	COG0398	Pfam SNARE associated Golgi protein
KO64_RS05295	COG0681	Belongs to the peptidase S26 family
KO64_RS05300	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KO64_RS05305	COG1846	Transcriptional regulator
KO64_RS05310	COG3180	Ammonia monooxygenase
KO64_RS05315	COG2814	Major facilitator Superfamily
KO64_RS05325	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KO64_RS05330	COG2323	membrane
KO64_RS05345	COG0420	3'-5' exonuclease activity
KO64_RS05350	COG0419	ATPase involved in DNA repair
KO64_RS05355	COG1403	HNH endonuclease
KO64_RS05395	COG0179	Fumarylacetoacetate (FAA) hydrolase
KO64_RS05415	COG0367	asparagine synthase
KO64_RS05420	COG1562	ergosterol biosynthetic process
KO64_RS05425	COG0534	Mate efflux family protein
KO64_RS05430	COG2207	Transcriptional regulator
KO64_RS05430	COG1917	Cupin 2, conserved barrel domain protein
KO64_RS05435	COG2318	DinB family
KO64_RS05440	COG1357	PFAM Pentapeptide repeats (8 copies)
KO64_RS05445	COG2153	protein acetylation
KO64_RS05450	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KO64_RS05450	COG0646	methionine synthase
KO64_RS05460	COG2996	Protein conserved in bacteria
KO64_RS05465	COG1744	ABC transporter substrate-binding protein PnrA-like
KO64_RS05470	COG0840	transmembrane signaling receptor activity
KO64_RS05475	COG2124	cytochrome p450
KO64_RS05480	COG1307	EDD domain protein, DegV family
KO64_RS05485	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KO64_RS05500	COG0561	phosphatase activity
KO64_RS05505	COG1073	alpha beta
KO64_RS05510	COG2151	metal-sulfur cluster biosynthetic enzyme
KO64_RS05520	COG0277	FAD linked oxidase domain protein
KO64_RS05525	COG2271	Major facilitator Superfamily
KO64_RS05535	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KO64_RS05545	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KO64_RS05550	COG0505	Belongs to the CarA family
KO64_RS05555	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KO64_RS05560	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KO64_RS05575	COG2267	carboxylic ester hydrolase activity
KO64_RS05585	COG1744	ABC transporter substrate-binding protein PnrA-like
KO64_RS05600	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KO64_RS05605	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KO64_RS05610	COG5504	Zn-dependent protease
KO64_RS05615	COG0444	Belongs to the ABC transporter superfamily
KO64_RS05620	COG4608	Belongs to the ABC transporter superfamily
KO64_RS05630	COG0601	transmembrane transport
KO64_RS05635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KO64_RS05645	COG0180	Tryptophanyl-tRNA synthetase
KO64_RS05650	COG4166	transmembrane transport
KO64_RS05655	COG0601	transmembrane transport
KO64_RS05660	COG0861	Integral membrane protein TerC family
KO64_RS05665	COG4862	establishment of competence for transformation
KO64_RS05670	COG4469	Competence protein
KO64_RS05675	COG1164	Oligoendopeptidase f
KO64_RS05685	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KO64_RS05690	COG2346	COG2346, Truncated hemoglobins
KO64_RS05695	COG0741	lytic transglycosylase activity
KO64_RS05700	COG4116	CYTH
KO64_RS05710	COG2357	RelA SpoT domain protein
KO64_RS05715	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KO64_RS05720	COG0564	pseudouridine synthase activity
KO64_RS05730	COG0475	glutathione-regulated potassium exporter activity
KO64_RS05730	COG0569	domain protein
KO64_RS05735	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KO64_RS05740	COG0352	thiamine-phosphate diphosphorylase activity
KO64_RS05745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KO64_RS05750	COG2104	thiamine diphosphate biosynthetic process
KO64_RS05760	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KO64_RS05765	COG0351	phosphomethylpyrimidine kinase
KO64_RS05770	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KO64_RS05825	COG0210	DNA helicase
KO64_RS05845	COG1131	(ABC) transporter
KO64_RS05855	COG2153	protein acetylation
KO64_RS05865	COG2382	esterase
KO64_RS05870	COG0626	cystathionine gamma-synthase activity
KO64_RS05875	COG0626	cystathionine gamma-synthase activity
KO64_RS05890	COG5444	nuclease activity
KO64_RS05905	COG0346	lactoylglutathione lyase activity
KO64_RS05910	COG2367	Beta-lactamase
KO64_RS05915	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KO64_RS05925	COG1846	Transcriptional regulator
KO64_RS05935	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
KO64_RS05940	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KO64_RS05945	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KO64_RS05950	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KO64_RS05950	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KO64_RS05955	COG1447	Phosphotransferase system cellobiose-specific component IIA
KO64_RS05990	COG1285	pathogenesis
KO64_RS06000	COG2205	protein histidine kinase activity
KO64_RS06010	COG3383	formate dehydrogenase (NAD+) activity
KO64_RS06015	COG2427	Protein of unknown function (DUF1641)
KO64_RS06020	COG2124	cytochrome p450
KO64_RS06025	COG1819	glycosyl
KO64_RS06035	COG1587	Uroporphyrinogen-III synthase
KO64_RS06040	COG0390	transport system, permease component
KO64_RS06045	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KO64_RS06050	COG0697	spore germination
KO64_RS06055	COG4297	protein containing double-stranded beta helix domain
KO64_RS06065	COG1252	NADH dehydrogenase
KO64_RS06075	COG2211	Major facilitator Superfamily
KO64_RS06080	COG1609	Transcriptional regulator
KO64_RS06085	COG0246	Mannitol dehydrogenase
KO64_RS06090	COG2721	sulfolactate sulfo-lyase activity
KO64_RS06095	COG0730	response to heat
KO64_RS06100	COG2318	DinB family
KO64_RS06105	COG0457	Tetratricopeptide repeat
KO64_RS06115	COG5632	N-Acetylmuramoyl-L-alanine amidase
KO64_RS06115	COG3409	Peptidoglycan-binding domain 1 protein
KO64_RS06115	COG1388	LysM domain
KO64_RS06125	COG4195	phage-related replication protein
KO64_RS06130	COG2856	Zn peptidase
KO64_RS06135	COG1396	sequence-specific DNA binding
KO64_RS06145	COG1522	sequence-specific DNA binding
KO64_RS06150	COG1484	DNA-dependent DNA replication
KO64_RS06165	COG1595	DNA-templated transcription, initiation
KO64_RS06170	COG3728	DNA packaging
KO64_RS06170	COG5484	DNA packaging
KO64_RS06175	COG1783	phage Terminase large subunit
KO64_RS06180	COG5518	Phage portal protein
KO64_RS06185	COG0338	D12 class N6 adenine-specific DNA methyltransferase
KO64_RS06190	COG4653	Phage capsid family
KO64_RS06235	COG3953	SLT domain
KO64_RS06235	COG5412	phage tail tape measure protein
KO64_RS06235	COG5412	phage tail tape measure protein
KO64_RS06235	COG3953	SLT domain
KO64_RS06235	COG3953	SLT domain
KO64_RS06235	COG5412	phage tail tape measure protein
KO64_RS06240	COG1652	LysM domain
KO64_RS06245	COG4193	domain, Protein
KO64_RS06255	COG3628	GPW Gp25 family protein
KO64_RS06260	COG3299	homolog of phage Mu protein gp47
KO64_RS06265	COG3778	Protein conserved in bacteria
KO64_RS06305	COG5632	N-Acetylmuramoyl-L-alanine amidase
KO64_RS06305	COG3409	Peptidoglycan-binding domain 1 protein
KO64_RS06320	COG0306	phosphate transporter
KO64_RS06325	COG1392	Phosphate transport regulator
KO64_RS06330	COG0531	amino acid
KO64_RS06335	COG0346	lactoylglutathione lyase activity
KO64_RS06340	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KO64_RS06345	COG0463	Glycosyl transferase, family 2
KO64_RS06350	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KO64_RS06355	COG0477	Major facilitator Superfamily
KO64_RS06360	COG2362	D-Aminopeptidase
KO64_RS06365	COG0601	transmembrane transport
KO64_RS06370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KO64_RS06375	COG0444	Belongs to the ABC transporter superfamily
KO64_RS06380	COG4166	transmembrane transport
KO64_RS06385	COG1619	proteins homologs of microcin C7 resistance protein MccF
KO64_RS06390	COG4948	Mandelate Racemase Muconate Lactonizing
KO64_RS06395	COG0791	NLP P60 protein
KO64_RS06400	COG4608	Belongs to the ABC transporter superfamily
KO64_RS06405	COG2706	6-phosphogluconolactonase activity
KO64_RS06410	COG1834	amidinotransferase
KO64_RS06415	COG1607	acyl-coa hydrolase
KO64_RS06420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KO64_RS06425	COG2076	Multidrug Resistance protein
KO64_RS06430	COG2076	Multidrug Resistance protein
KO64_RS06435	COG0788	formyltetrahydrofolate deformylase activity
KO64_RS06440	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KO64_RS06450	COG1764	response to oxidative stress
KO64_RS06455	COG1846	Transcriptional regulator
KO64_RS06460	COG1764	response to oxidative stress
KO64_RS06475	COG0457	Tetratricopeptide repeat
KO64_RS06475	COG0463	Glycosyl transferase, family 2
KO64_RS06485	COG2814	Major facilitator Superfamily
KO64_RS06490	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KO64_RS06500	COG1404	Belongs to the peptidase S8 family
KO64_RS06505	COG1366	Belongs to the anti-sigma-factor antagonist family
KO64_RS06510	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KO64_RS06515	COG1122	ATPase activity
KO64_RS06520	COG4721	ABC-type cobalt transport system, permease component
KO64_RS06525	COG1388	LysM domain
KO64_RS06525	COG3858	chitin binding
KO64_RS06530	COG2239	Acts as a magnesium transporter
KO64_RS06535	COG0789	Transcriptional regulator
KO64_RS06545	COG1846	Transcriptional regulator
KO64_RS06550	COG0726	polysaccharide deacetylase
KO64_RS06555	COG3285	dna ligase
KO64_RS06555	COG1793	dna ligase
KO64_RS06560	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KO64_RS06565	COG0586	Pfam SNARE associated Golgi protein
KO64_RS06570	COG0861	Integral membrane protein TerC family
KO64_RS06575	COG1191	sigma factor activity
KO64_RS06600	COG2801	Transposase and inactivated derivatives
KO64_RS06610	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KO64_RS06615	COG2323	membrane
KO64_RS06620	COG3594	Acyltransferase
KO64_RS06625	COG5002	protein histidine kinase activity
KO64_RS06630	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KO64_RS06645	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KO64_RS06650	COG0436	Aminotransferase
KO64_RS06680	COG3852	Histidine kinase
KO64_RS06685	COG1846	Transcriptional regulator
KO64_RS06690	COG1360	Flagellar Motor Protein
KO64_RS06695	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KO64_RS06700	COG0542	response to heat
KO64_RS06710	COG3949	Membrane
KO64_RS06725	COG0720	synthase
KO64_RS06730	COG0602	queuosine metabolic process
KO64_RS06740	COG1733	regulation of RNA biosynthetic process
KO64_RS06745	COG1028	Short-chain dehydrogenase reductase Sdr
KO64_RS06755	COG1388	LysM domain
KO64_RS06755	COG4641	Protein conserved in bacteria
KO64_RS06760	COG1388	LysM domain
KO64_RS06765	COG3858	chitin binding
KO64_RS06775	COG4873	Protein conserved in bacteria
KO64_RS06785	COG3773	Cell wall hydrolase
KO64_RS06790	COG2244	polysaccharide biosynthetic process
KO64_RS06795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KO64_RS06800	COG2217	Heavy metal translocating P-type atpase
KO64_RS06805	COG0006	proline dipeptidase activity
KO64_RS06810	COG1609	Transcriptional regulator
KO64_RS06815	COG3711	transcriptional antiterminator
KO64_RS06820	COG2190	(PTS) system
KO64_RS06820	COG1263	PTS System
KO64_RS06820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KO64_RS06825	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KO64_RS06830	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KO64_RS06840	COG1533	DNA photolyase activity
KO64_RS06845	COG0840	transmembrane signaling receptor activity
KO64_RS06850	COG2084	Dehydrogenase
KO64_RS06855	COG2340	Cysteine-rich secretory protein family
KO64_RS06860	COG0768	penicillin binding
KO64_RS06865	COG4191	Histidine kinase
KO64_RS06870	COG0436	Aminotransferase
KO64_RS06875	COG0784	Response regulator, receiver
KO64_RS06875	COG0835	chemotaxis
KO64_RS06885	COG2814	Major facilitator Superfamily
KO64_RS06890	COG1376	ErfK ybiS ycfS ynhG family protein
KO64_RS06895	COG1408	metallophosphoesterase
KO64_RS06900	COG1028	Short-chain dehydrogenase reductase Sdr
KO64_RS06910	COG2200	EAL domain
KO64_RS06915	COG4703	Protein of unknown function (DUF1797)
KO64_RS06920	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KO64_RS06930	COG0517	IMP dehydrogenase activity
KO64_RS06935	COG0583	DNA-binding transcription factor activity
KO64_RS06940	COG0716	FMN binding
KO64_RS06950	COG0716	FMN binding
KO64_RS06970	COG0668	transmembrane transport
KO64_RS06975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KO64_RS06995	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KO64_RS07000	COG0303	'Molybdopterin
KO64_RS07005	COG1763	Mo-molybdopterin cofactor biosynthetic process
KO64_RS07010	COG0314	molybdopterin synthase activity
KO64_RS07015	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KO64_RS07025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KO64_RS07030	COG1136	(ABC) transporter
KO64_RS07035	COG0577	efflux transmembrane transporter activity
KO64_RS07040	COG1349	DNA-binding transcription factor activity
KO64_RS07045	COG1105	Belongs to the carbohydrate kinase PfkB family
KO64_RS07050	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KO64_RS07050	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KO64_RS07050	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KO64_RS07055	COG0681	Belongs to the peptidase S26 family
KO64_RS07065	COG0488	(ABC) transporter
KO64_RS07070	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KO64_RS07075	COG2309	aminopeptidase activity
KO64_RS07080	COG1077	Cell shape determining protein MreB Mrl
KO64_RS07090	COG2002	toxin-antitoxin pair type II binding
KO64_RS07095	COG3852	Histidine kinase
KO64_RS07100	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
KO64_RS07100	COG2105	PFAM AIG2 family protein
KO64_RS07105	COG0569	domain protein
KO64_RS07115	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KO64_RS07125	COG0561	phosphatase activity
KO64_RS07130	COG0242	peptide deformylase activity
KO64_RS07140	COG0497	DNA recombination
KO64_RS07155	COG3321	synthase
KO64_RS07155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KO64_RS07155	COG4221	oxidoreductase activity
KO64_RS07155	COG1028	Short-chain dehydrogenase reductase Sdr
KO64_RS07160	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KO64_RS07160	COG3321	synthase
KO64_RS07160	COG0300	oxidoreductase activity
KO64_RS07160	COG4221	oxidoreductase activity
KO64_RS07165	COG3321	synthase
KO64_RS07165	COG1028	Short-chain dehydrogenase reductase Sdr
KO64_RS07165	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KO64_RS07165	COG4221	oxidoreductase activity
KO64_RS07170	COG3321	synthase
KO64_RS07170	COG1028	Short-chain dehydrogenase reductase Sdr
KO64_RS07170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KO64_RS07170	COG0300	oxidoreductase activity
KO64_RS07170	COG0318	PFAM AMP-dependent synthetase and ligase
KO64_RS07175	COG3321	synthase
KO64_RS07175	COG0300	oxidoreductase activity
KO64_RS07175	COG4221	oxidoreductase activity
KO64_RS07175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KO64_RS07180	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KO64_RS07180	COG0300	oxidoreductase activity
KO64_RS07180	COG3321	synthase
KO64_RS07180	COG4221	oxidoreductase activity
KO64_RS07185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KO64_RS07185	COG1028	Short-chain dehydrogenase reductase Sdr
KO64_RS07185	COG3321	synthase
KO64_RS07185	COG4221	oxidoreductase activity
KO64_RS07190	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KO64_RS07195	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KO64_RS07200	COG0022	dehydrogenase e1 component
KO64_RS07205	COG0508	dehydrogenase complex catalyzes the overall conversion of
KO64_RS07210	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KO64_RS07215	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KO64_RS07225	COG1982	Orn Lys Arg decarboxylase major
KO64_RS07245	COG0483	inositol monophosphate 1-phosphatase activity
KO64_RS07255	COG3227	Zinc metalloprotease (Elastase)
KO64_RS07275	COG1217	gtp-binding protein TYPA
KO64_RS07285	COG4896	Protein conserved in bacteria
KO64_RS07295	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KO64_RS07300	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KO64_RS07305	COG2066	Belongs to the glutaminase family
KO64_RS07315	COG0772	Belongs to the SEDS family
KO64_RS07320	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KO64_RS07335	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KO64_RS07335	COG2010	Cytochrome c
KO64_RS07340	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KO64_RS07345	COG1845	cytochrome c oxidase, subunit III
KO64_RS07350	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KO64_RS07355	COG3336	cytochrome c oxidase
KO64_RS07365	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KO64_RS07370	COG2340	Cysteine-rich secretory protein family
KO64_RS07385	COG3679	Belongs to the UPF0342 family
KO64_RS07400	COG0742	ribosomal rna small subunit methyltransferase
KO64_RS07410	COG3314	Sporulation integral membrane protein YlbJ
KO64_RS07415	COG1752	Esterase of the alpha-beta hydrolase superfamily
KO64_RS07420	COG3480	Lon protease (S16) C-terminal proteolytic domain
KO64_RS07430	COG1399	metal-binding, possibly nucleic acid-binding protein
KO64_RS07445	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KO64_RS07465	COG4839	cell division protein FtsL
KO64_RS07470	COG0768	penicillin binding
KO64_RS07475	COG0768	penicillin binding
KO64_RS07495	COG0772	Belongs to the SEDS family
KO64_RS07510	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KO64_RS07515	COG0849	cell division
KO64_RS07520	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KO64_RS07525	COG4412	M6 family metalloprotease domain protein
KO64_RS07525	COG1404	Belongs to the peptidase S8 family
KO64_RS07535	COG1191	sigma factor activity
KO64_RS07540	COG1191	sigma factor activity
KO64_RS07545	COG1119	ATPase activity
KO64_RS07550	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KO64_RS07555	COG1873	PFAM PRC-barrel domain
KO64_RS07560	COG1496	oxidoreductase activity
KO64_RS07565	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KO64_RS07575	COG0762	integral membrane protein
KO64_RS07580	COG2302	S4 RNA-binding domain
KO64_RS07585	COG3599	regulation of cell shape
KO64_RS07595	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KO64_RS07600	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KO64_RS07610	COG0564	pseudouridine synthase activity
KO64_RS07620	COG2233	PERMEase
KO64_RS07630	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KO64_RS07635	COG0505	Belongs to the CarA family
KO64_RS07640	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KO64_RS07655	COG0284	orotidine-5'-phosphate decarboxylase activity
KO64_RS07660	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KO64_RS07670	COG0306	phosphate transporter
KO64_RS07685	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KO64_RS07690	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
KO64_RS07695	COG1648	precorrin-2 dehydrogenase activity
KO64_RS07705	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KO64_RS07710	COG1561	YicC-like family, N-terminal region
KO64_RS07720	COG0194	GDP metabolic process
KO64_RS07730	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KO64_RS07735	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KO64_RS07740	COG0242	peptide deformylase activity
KO64_RS07750	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KO64_RS07750	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KO64_RS07760	COG0631	protein serine/threonine phosphatase activity
KO64_RS07765	COG2815	serine threonine protein kinase
KO64_RS07765	COG0515	serine threonine protein kinase
KO64_RS07775	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KO64_RS07780	COG1564	THIamine pyrophosphokinase
KO64_RS07795	COG1302	Protein conserved in bacteria
KO64_RS07800	COG1461	Dihydroxyacetone kinase
KO64_RS07805	COG1760	l-serine dehydratase
KO64_RS07810	COG1760	l-serine dehydratase
KO64_RS07815	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KO64_RS07830	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KO64_RS07835	COG1028	Short-chain dehydrogenase reductase Sdr
KO64_RS07850	COG1196	nuclear chromosome segregation
KO64_RS07855	COG0552	protein localization to endoplasmic reticulum
KO64_RS07870	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KO64_RS07880	COG1837	Belongs to the UPF0109 family
KO64_RS07905	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KO64_RS07920	COG2257	FlhB HrpN YscU SpaS Family
KO64_RS07930	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KO64_RS07935	COG0758	DNA mediated transformation
KO64_RS07940	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KO64_RS07950	COG4974	Belongs to the 'phage' integrase family
KO64_RS07970	COG1815	bacterial-type flagellum-dependent cell motility
KO64_RS07975	COG1558	bacterial-type flagellum-dependent cell motility
KO64_RS07980	COG1677	Flagellar hook-basal body complex protein FliE
KO64_RS07985	COG1766	The M ring may be actively involved in energy transduction
KO64_RS07990	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KO64_RS07995	COG1317	bacterial-type flagellum organization
KO64_RS08000	COG1157	protein secretion by the type III secretion system
KO64_RS08005	COG2882	bacterial-type flagellum organization
KO64_RS08010	COG3334	PFAM MgtE intracellular
KO64_RS08015	COG3144	bacterial-type flagellum assembly
KO64_RS08020	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
KO64_RS08025	COG4786	Flagellar basal body rod
KO64_RS08030	COG1582	Flagellar protein (FlbD)
KO64_RS08035	COG1580	Controls the rotational direction of flagella during chemotaxis
KO64_RS08040	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KO64_RS08045	COG1776	CheC inhibitor of MCP methylation
KO64_RS08045	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KO64_RS08050	COG2201	protein-glutamate methylesterase activity
KO64_RS08055	COG3190	flagellar
KO64_RS08060	COG1338	Plays a role in the flagellum-specific transport system
KO64_RS08065	COG1987	bacterial-type flagellum assembly
KO64_RS08070	COG1684	flagellar biosynthetic protein fliR
KO64_RS08075	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KO64_RS08080	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KO64_RS08085	COG1419	protein localization to endoplasmic reticulum
KO64_RS08090	COG0455	bacterial-type flagellum organization
KO64_RS08095	COG2201	protein-glutamate methylesterase activity
KO64_RS08100	COG0643	Histidine kinase
KO64_RS08100	COG2198	Histidine kinase
KO64_RS08105	COG0835	chemotaxis
KO64_RS08110	COG1776	CheC inhibitor of MCP methylation
KO64_RS08120	COG1191	sigma factor activity
KO64_RS08150	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KO64_RS08155	COG4589	Belongs to the CDS family
KO64_RS08165	COG0750	zinc metalloprotease
KO64_RS08175	COG2176	DNA-directed DNA polymerase activity
KO64_RS08185	COG0195	Participates in both transcription termination and antitermination
KO64_RS08190	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KO64_RS08195	COG1358	cellular component organization or biogenesis
KO64_RS08205	COG1550	Protein conserved in bacteria
KO64_RS08220	COG0196	riboflavin kinase activity
KO64_RS08235	COG0726	polysaccharide deacetylase
KO64_RS08240	COG0612	Peptidase, M16
KO64_RS08245	COG1873	PFAM PRC-barrel domain
KO64_RS08250	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KO64_RS08255	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KO64_RS08260	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KO64_RS08265	COG0527	aspartate kinase activity
KO64_RS08275	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KO64_RS08280	COG0740	serine-type endopeptidase activity
KO64_RS08290	COG4980	gas vesicle protein
KO64_RS08290	COG1674	ftsk spoiiie
KO64_RS08295	COG2188	Transcriptional regulator
KO64_RS08300	COG2814	Major facilitator Superfamily
KO64_RS08305	COG1846	Transcriptional regulator
KO64_RS08310	COG1033	growth of symbiont in host cell
KO64_RS08310	COG2409	Drug exporters of the RND superfamily
KO64_RS08315	COG0612	Peptidase, M16
KO64_RS08320	COG0612	Peptidase, M16
KO64_RS08325	COG0300	oxidoreductase activity
KO64_RS08340	COG1426	Protein conserved in bacteria
KO64_RS08345	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KO64_RS08360	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KO64_RS08370	COG1692	metallophosphoesterase
KO64_RS08375	COG2359	stage V sporulation protein S
KO64_RS08395	COG4550	Control of competence regulator ComK, YlbF/YmcA
KO64_RS08415	COG0582	viral genome integration into host DNA
KO64_RS08450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KO64_RS08455	COG3425	synthase
KO64_RS08460	COG1024	Enoyl-CoA hydratase
KO64_RS08465	COG1024	Enoyl-CoA hydratase
KO64_RS08470	COG1028	Short-chain dehydrogenase reductase Sdr
KO64_RS08470	COG0318	PFAM AMP-dependent synthetase and ligase
KO64_RS08470	COG3321	synthase
KO64_RS08470	COG0300	oxidoreductase activity
KO64_RS08470	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KO64_RS08475	COG4221	oxidoreductase activity
KO64_RS08475	COG3321	synthase
KO64_RS08475	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KO64_RS08475	COG0300	oxidoreductase activity
KO64_RS08480	COG3321	synthase
KO64_RS08480	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KO64_RS08480	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KO64_RS08480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KO64_RS08480	COG1028	Short-chain dehydrogenase reductase Sdr
KO64_RS08480	COG3321	synthase
KO64_RS08480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KO64_RS08480	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KO64_RS08480	COG1028	Short-chain dehydrogenase reductase Sdr
KO64_RS08480	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KO64_RS08485	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KO64_RS08485	COG3321	synthase
KO64_RS08485	COG4221	oxidoreductase activity
KO64_RS08485	COG1028	Short-chain dehydrogenase reductase Sdr
KO64_RS08490	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KO64_RS08490	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KO64_RS08490	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KO64_RS08490	COG3321	synthase
KO64_RS08495	COG2124	cytochrome p450
KO64_RS08500	COG3209	COG3209 Rhs family protein
KO64_RS08505	COG3619	membrane
KO64_RS08515	COG2801	Transposase and inactivated derivatives
KO64_RS08525	COG1404	Belongs to the peptidase S8 family
KO64_RS08535	COG4195	phage-related replication protein
KO64_RS08540	COG1764	response to oxidative stress
KO64_RS08550	COG2076	Multidrug Resistance protein
KO64_RS08590	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KO64_RS08595	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KO64_RS08600	COG4112	unkown
KO64_RS08605	COG0860	N-Acetylmuramoyl-L-alanine amidase
KO64_RS08615	COG0464	growth
KO64_RS08620	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KO64_RS08625	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KO64_RS08630	COG0789	Transcriptional regulator
KO64_RS08635	COG0174	glutamine synthetase
KO64_RS08650	COG2211	Major facilitator Superfamily
KO64_RS08655	COG3507	Belongs to the glycosyl hydrolase 43 family
KO64_RS08670	COG1070	Carbohydrate kinase
KO64_RS08675	COG3848	Pyruvate phosphate dikinase
KO64_RS08675	COG0574	Belongs to the PEP-utilizing enzyme family
KO64_RS08690	COG1064	alcohol dehydrogenase
KO64_RS08720	COG0456	acetyltransferase
KO64_RS08755	COG3397	chitin binding
KO64_RS08765	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KO64_RS08775	COG5434	Belongs to the glycosyl hydrolase 28 family
KO64_RS08780	COG0756	dUTP diphosphatase activity
KO64_RS08785	COG4195	phage-related replication protein
KO64_RS08815	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KO64_RS08825	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KO64_RS08845	COG0785	Cytochrome C biogenesis protein
KO64_RS08850	COG2201	protein-glutamate methylesterase activity
KO64_RS08855	COG4846	Membrane protein involved in cytochrome C biogenesis
KO64_RS08865	COG0071	Belongs to the small heat shock protein (HSP20) family
KO64_RS08880	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KO64_RS08885	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KO64_RS08905	COG0824	Thioesterase
KO64_RS08915	COG4841	protein insertion into membrane
KO64_RS08925	COG1832	CoA-binding protein
KO64_RS08930	COG0187	DNA topoisomerase II activity
KO64_RS08935	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KO64_RS08945	COG1115	amino acid carrier protein
KO64_RS08955	COG2801	Transposase and inactivated derivatives
KO64_RS08965	COG1063	alcohol dehydrogenase
KO64_RS08970	COG0800	Aldolase
KO64_RS08975	COG1312	Catalyzes the dehydration of D-mannonate
KO64_RS08980	COG1028	Short-chain dehydrogenase reductase Sdr
KO64_RS08985	COG1609	Transcriptional regulator
KO64_RS08990	COG2271	Major facilitator Superfamily
KO64_RS09035	COG2205	protein histidine kinase activity
KO64_RS09040	COG0745	RESPONSE REGULATOR receiver
KO64_RS09050	COG3507	Belongs to the glycosyl hydrolase 43 family
KO64_RS09075	COG1028	Short-chain dehydrogenase reductase Sdr
KO64_RS09080	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KO64_RS09085	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KO64_RS09090	COG2610	gluconate transmembrane transporter activity
KO64_RS09095	COG2124	cytochrome p450
KO64_RS09115	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KO64_RS09125	COG2246	polysaccharide biosynthetic process
KO64_RS09130	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KO64_RS09135	COG0586	Pfam SNARE associated Golgi protein
KO64_RS09140	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KO64_RS09145	COG1024	Enoyl-CoA hydratase
KO64_RS09150	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KO64_RS09155	COG0511	ligase activity, forming carbon-carbon bonds
KO64_RS09160	COG0439	Biotin carboxylase
KO64_RS09165	COG0318	PFAM AMP-dependent synthetase and ligase
KO64_RS09170	COG1960	acyl-CoA dehydrogenase activity
KO64_RS09175	COG1649	PFAM Uncharacterised BCR, COG1649
KO64_RS09185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KO64_RS09185	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KO64_RS09190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KO64_RS09195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KO64_RS09200	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KO64_RS09205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KO64_RS09210	COG2027	D-alanyl-D-alanine carboxypeptidase
KO64_RS09215	COG2017	converts alpha-aldose to the beta-anomer
KO64_RS09220	COG0534	Mate efflux family protein
KO64_RS09235	COG0582	viral genome integration into host DNA
KO64_RS09240	COG0166	Belongs to the GPI family
KO64_RS09245	COG0405	Gamma-glutamyltransferase
KO64_RS09250	COG2814	Major facilitator Superfamily
KO64_RS09255	COG0640	Transcriptional regulator
KO64_RS09260	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KO64_RS09270	COG0604	alcohol dehydrogenase
KO64_RS09275	COG0493	'glutamate synthase
KO64_RS09280	COG0067	glutamate synthase
KO64_RS09280	COG0069	glutamate synthase activity
KO64_RS09280	COG0070	glutamate synthase
KO64_RS09285	COG0583	DNA-binding transcription factor activity
KO64_RS09290	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KO64_RS09305	COG0300	oxidoreductase activity
KO64_RS09310	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KO64_RS09320	COG2814	Major facilitator Superfamily
KO64_RS09325	COG1070	Carbohydrate kinase
KO64_RS09330	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KO64_RS09335	COG0243	molybdopterin cofactor binding
KO64_RS09340	COG2801	Transposase and inactivated derivatives
KO64_RS09375	COG5444	nuclease activity
KO64_RS09380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KO64_RS09385	COG2207	Transcriptional regulator
KO64_RS09385	COG0662	Cupin 2, conserved barrel domain protein
KO64_RS09390	COG1309	transcriptional regulator
KO64_RS09395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KO64_RS09405	COG0640	Transcriptional regulator
KO64_RS09410	COG0741	lytic transglycosylase activity
KO64_RS09415	COG2322	membrane
KO64_RS09430	COG1619	proteins homologs of microcin C7 resistance protein MccF
KO64_RS09440	COG3584	3D domain protein
KO64_RS09440	COG1388	LysM domain
KO64_RS09445	COG0514	ATP-dependent DNA helicase (RecQ)
KO64_RS09450	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KO64_RS09455	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KO64_RS09470	COG0071	Belongs to the small heat shock protein (HSP20) family
KO64_RS09495	COG1012	belongs to the aldehyde dehydrogenase family
KO64_RS09500	COG1657	PFAM Prenyltransferase squalene oxidase
KO64_RS09505	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KO64_RS09510	COG0733	neurotransmitter:sodium symporter activity
KO64_RS09515	COG0385	Bile acid
KO64_RS09520	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KO64_RS09525	COG0508	dehydrogenase complex catalyzes the overall conversion of
KO64_RS09535	COG4548	von Willebrand factor, type A
KO64_RS09540	COG0714	Associated with various cellular activities
KO64_RS09545	COG2032	superoxide dismutase activity
KO64_RS09550	COG0791	NLP P60 protein
KO64_RS09550	COG1388	LysM domain
KO64_RS09555	COG1819	glycosyl
KO64_RS09560	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KO64_RS09565	COG0534	Mate efflux family protein
KO64_RS09570	COG1366	Belongs to the anti-sigma-factor antagonist family
KO64_RS09575	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KO64_RS09580	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KO64_RS09590	COG2962	Rard protein
KO64_RS09605	COG1942	4-Oxalocrotonate Tautomerase
KO64_RS09615	COG1733	regulation of RNA biosynthetic process
KO64_RS09620	COG0778	Nitroreductase
KO64_RS09625	COG0400	carboxylic ester hydrolase activity
KO64_RS09630	COG0346	lactoylglutathione lyase activity
KO64_RS09640	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KO64_RS09650	COG2723	6-phospho-beta-galactosidase activity
KO64_RS09655	COG2188	Transcriptional regulator
KO64_RS09660	COG3409	Peptidoglycan-binding domain 1 protein
KO64_RS09660	COG0793	Belongs to the peptidase S41A family
KO64_RS09665	COG2226	methyltransferase
KO64_RS09675	COG1876	peptidase activity
KO64_RS09690	COG0671	phosphoesterase, PA-phosphatase related
KO64_RS09715	COG1509	lysine 2,3-aminomutase activity
KO64_RS09720	COG0456	acetyltransferase
KO64_RS09725	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KO64_RS09730	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KO64_RS09735	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KO64_RS09740	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KO64_RS09755	COG0456	acetyltransferase
KO64_RS09760	COG0463	Glycosyl transferase, family 2
KO64_RS09775	COG4641	Protein conserved in bacteria
KO64_RS09785	COG1086	Polysaccharide biosynthesis protein
KO64_RS09790	COG3331	DNA recombination
KO64_RS09810	COG1388	LysM domain
KO64_RS09815	COG0457	Tetratricopeptide repeat
KO64_RS09835	COG5444	nuclease activity
KO64_RS09840	COG4282	regulation of fungal-type cell wall biogenesis
KO64_RS09845	COG1525	nuclease
KO64_RS09850	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KO64_RS09870	COG1846	Transcriptional regulator
KO64_RS09875	COG4698	Protein conserved in bacteria
KO64_RS09880	COG2755	lipolytic protein G-D-S-L family
KO64_RS09885	COG1999	signal sequence binding
KO64_RS09895	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KO64_RS09900	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KO64_RS09905	COG1272	protein, Hemolysin III
KO64_RS09910	COG0204	Acyl-transferase
KO64_RS09915	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KO64_RS09930	COG2136	Putative SAM-dependent methyltransferase
KO64_RS09930	COG2521	methyltransferase
KO64_RS09945	COG1413	lyase activity
KO64_RS09950	COG1418	mRNA catabolic process
KO64_RS09955	COG0386	Belongs to the glutathione peroxidase family
KO64_RS09965	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KO64_RS09970	COG1278	Cold shock
KO64_RS09990	COG0328	RNA-DNA hybrid ribonuclease activity
KO64_RS09995	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KO64_RS10000	COG0328	RNA-DNA hybrid ribonuclease activity
KO64_RS10010	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KO64_RS10020	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KO64_RS10025	COG1755	Isoprenylcysteine carboxyl methyltransferase
KO64_RS10030	COG3424	synthase
KO64_RS10050	COG2323	membrane
KO64_RS10055	COG1335	isochorismatase
KO64_RS10065	COG2233	PERMEase
KO64_RS10075	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KO64_RS10080	COG1199	ATP-dependent helicase activity
KO64_RS10090	COG0116	Belongs to the methyltransferase superfamily
KO64_RS10105	COG3359	exonuclease
KO64_RS10110	COG1205	dead DEAH box helicase
KO64_RS10110	COG1111	helicase
KO64_RS10115	COG2190	(PTS) system
KO64_RS10120	COG0071	Belongs to the small heat shock protein (HSP20) family
KO64_RS10160	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KO64_RS10160	COG4499	WXG100 protein secretion system (Wss), protein YukC
KO64_RS10170	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KO64_RS10175	COG3935	DnaD domain protein
KO64_RS10185	COG0436	Aminotransferase
KO64_RS10190	COG5353	protein conserved in bacteria
KO64_RS10195	COG1199	ATP-dependent helicase activity
KO64_RS10195	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KO64_RS10225	COG0438	transferase activity, transferring glycosyl groups
KO64_RS10230	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KO64_RS10245	COG1694	Mazg nucleotide pyrophosphohydrolase
KO64_RS10250	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KO64_RS10255	COG2140	Oxalate decarboxylase
KO64_RS10265	COG4347	Protein of unknown function (DUF1405)
KO64_RS10270	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KO64_RS10270	COG2010	Cytochrome c
KO64_RS10275	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KO64_RS10280	COG0723	plastoquinol--plastocyanin reductase activity
KO64_RS10295	COG0457	Tetratricopeptide repeat
KO64_RS10305	COG0287	Prephenate dehydrogenase
KO64_RS10340	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KO64_RS10345	COG4401	Chorismate mutase type I
KO64_RS10360	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KO64_RS10365	COG0105	UTP biosynthetic process
KO64_RS10370	COG0142	geranyltranstransferase activity
KO64_RS10380	COG0142	geranyltranstransferase activity
KO64_RS10395	COG0776	regulation of translation
KO64_RS10400	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KO64_RS10435	COG0539	negative regulation of cytoplasmic translation
KO64_RS10445	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
KO64_RS10450	COG2959	enzyme of heme biosynthesis
KO64_RS10455	COG3773	Cell wall hydrolase
KO64_RS10455	COG3409	Peptidoglycan-binding domain 1 protein
KO64_RS10460	COG2339	peptidase activity
KO64_RS10465	COG0492	ferredoxin-NADP+ reductase activity
KO64_RS10470	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KO64_RS10475	COG4862	establishment of competence for transformation
KO64_RS10480	COG1408	metallophosphoesterase
KO64_RS10490	COG1388	LysM domain
KO64_RS10495	COG1266	CAAX protease self-immunity
KO64_RS10500	COG0514	ATP-dependent DNA helicase (RecQ)
KO64_RS10505	COG4955	Helix-turn-helix domain
KO64_RS10510	COG1141	Ferredoxin
KO64_RS10515	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KO64_RS10520	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KO64_RS10530	COG1595	DNA-templated transcription, initiation
KO64_RS10535	COG5002	protein histidine kinase activity
KO64_RS10540	COG0745	RESPONSE REGULATOR receiver
KO64_RS10545	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KO64_RS10550	COG1333	cytochrome c biogenesis protein
KO64_RS10555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KO64_RS10560	COG1187	pseudouridine synthase activity
KO64_RS10565	COG0700	Nucleoside recognition
KO64_RS10570	COG2715	membrane protein required for spore maturation
KO64_RS10575	COG1686	Belongs to the peptidase S11 family
KO64_RS10595	COG1547	Domain of unknown function (DUF309)
KO64_RS10600	COG0456	acetyltransferase
KO64_RS10615	COG0307	riboflavin synthase, alpha
KO64_RS10620	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KO64_RS10620	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KO64_RS10630	COG0681	Belongs to the peptidase S26 family
KO64_RS10640	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KO64_RS10645	COG4086	secreted protein
KO64_RS10650	COG0019	diaminopimelate decarboxylase activity
KO64_RS10655	COG0697	spore germination
KO64_RS10670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KO64_RS10690	COG1191	sigma factor activity
KO64_RS10700	COG1366	Belongs to the anti-sigma-factor antagonist family
KO64_RS10705	COG1686	Belongs to the peptidase S11 family
KO64_RS10710	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KO64_RS10715	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KO64_RS10720	COG4974	Belongs to the 'phage' integrase family
KO64_RS10730	COG0735	belongs to the Fur family
KO64_RS10735	COG1300	Membrane
KO64_RS10750	COG0281	malic enzyme
KO64_RS10755	COG1757	Na H antiporter
KO64_RS10760	COG1027	Aspartate ammonia-lyase
KO64_RS10765	COG0252	asparaginase activity
KO64_RS10770	COG1396	sequence-specific DNA binding
KO64_RS10775	COG1379	DNA repair
KO64_RS10780	COG0494	nUDIX hydrolase
KO64_RS10790	COG0667	Aldo Keto reductase
KO64_RS10800	COG1073	alpha beta
KO64_RS10810	COG4918	Iron-sulphur cluster biosynthesis
KO64_RS10815	COG0456	acetyltransferase
KO64_RS10815	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KO64_RS10820	COG2329	Antibiotic biosynthesis monooxygenase
KO64_RS10825	COG0456	acetyltransferase
KO64_RS10830	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KO64_RS10845	COG0628	permease
KO64_RS10850	COG0346	lactoylglutathione lyase activity
KO64_RS10860	COG3048	D-serine ammonia-lyase activity
KO64_RS10865	COG0300	oxidoreductase activity
KO64_RS10870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KO64_RS10875	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KO64_RS10880	COG1024	Enoyl-CoA hydratase
KO64_RS10885	COG3425	synthase
KO64_RS10890	COG2124	cytochrome p450
KO64_RS10895	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KO64_RS10895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KO64_RS10895	COG3321	synthase
KO64_RS10895	COG1028	Short-chain dehydrogenase reductase Sdr
KO64_RS10895	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KO64_RS10900	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KO64_RS10900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KO64_RS10900	COG1028	Short-chain dehydrogenase reductase Sdr
KO64_RS10900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KO64_RS10900	COG3321	synthase
KO64_RS10905	COG3321	synthase
KO64_RS10905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KO64_RS10905	COG0300	oxidoreductase activity
KO64_RS10905	COG1028	Short-chain dehydrogenase reductase Sdr
KO64_RS10905	COG0318	PFAM AMP-dependent synthetase and ligase
KO64_RS10910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KO64_RS10910	COG1028	Short-chain dehydrogenase reductase Sdr
KO64_RS10910	COG0300	oxidoreductase activity
KO64_RS10910	COG3321	synthase
KO64_RS10910	COG0318	PFAM AMP-dependent synthetase and ligase
KO64_RS10915	COG3321	synthase
KO64_RS10915	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KO64_RS10915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KO64_RS10915	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KO64_RS10915	COG1028	Short-chain dehydrogenase reductase Sdr
KO64_RS10920	COG0300	oxidoreductase activity
KO64_RS10920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KO64_RS10920	COG0318	PFAM AMP-dependent synthetase and ligase
KO64_RS10920	COG1028	Short-chain dehydrogenase reductase Sdr
KO64_RS10920	COG3321	synthase
KO64_RS10925	COG3321	synthase
KO64_RS10925	COG1028	Short-chain dehydrogenase reductase Sdr
KO64_RS10925	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KO64_RS10925	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KO64_RS10925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KO64_RS10930	COG1028	Short-chain dehydrogenase reductase Sdr
KO64_RS10935	COG0318	PFAM AMP-dependent synthetase and ligase
KO64_RS10950	COG2070	2-Nitropropane dioxygenase
KO64_RS10950	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KO64_RS10955	COG0250	Participates in transcription elongation, termination and antitermination
KO64_RS10975	COG0596	Alpha beta hydrolase
KO64_RS10990	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KO64_RS10995	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KO64_RS11010	COG0706	membrane insertase activity
KO64_RS11015	COG2195	Cleaves the N-terminal amino acid of tripeptides
KO64_RS11020	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KO64_RS11025	COG0346	lactoylglutathione lyase activity
KO64_RS11030	COG1376	ErfK ybiS ycfS ynhG family protein
KO64_RS11035	COG4129	membrane
KO64_RS11040	COG1126	abc transporter atp-binding protein
KO64_RS11045	COG0765	amino acid transport
KO64_RS11050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KO64_RS11060	COG1597	lipid kinase activity
KO64_RS11065	COG0508	dehydrogenase complex catalyzes the overall conversion of
KO64_RS11070	COG0022	dehydrogenase e1 component
KO64_RS11075	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KO64_RS11080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KO64_RS11085	COG3426	butyrate kinase activity
KO64_RS11090	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KO64_RS11095	COG0280	phosphate acetyltransferase
KO64_RS11100	COG3829	transcription factor binding
KO64_RS11100	COG3290	protein histidine kinase activity
KO64_RS11110	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KO64_RS11115	COG2079	MmgE PrpD family protein
KO64_RS11120	COG0372	Belongs to the citrate synthase family
KO64_RS11125	COG1960	acyl-CoA dehydrogenase activity
KO64_RS11130	COG1250	3-hydroxyacyl-CoA dehydrogenase
KO64_RS11135	COG0183	Belongs to the thiolase family
KO64_RS11140	COG0584	glycerophosphoryl diester phosphodiesterase
KO64_RS11145	COG0860	N-Acetylmuramoyl-L-alanine amidase
KO64_RS11170	COG1902	pentaerythritol trinitrate reductase activity
KO64_RS11185	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KO64_RS11190	COG0745	RESPONSE REGULATOR receiver
KO64_RS11195	COG0750	zinc metalloprotease
KO64_RS11200	COG0497	DNA recombination
KO64_RS11210	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KO64_RS11220	COG0142	geranyltranstransferase activity
KO64_RS11230	COG1570	exodeoxyribonuclease VII activity
KO64_RS11245	COG1302	Protein conserved in bacteria
KO64_RS11250	COG0439	Biotin carboxylase
KO64_RS11255	COG0511	ligase activity, forming carbon-carbon bonds
KO64_RS11295	COG3854	ATPases associated with a variety of cellular activities
KO64_RS11310	COG0006	proline dipeptidase activity
KO64_RS11320	COG3872	metal-dependent enzyme
KO64_RS11330	COG1752	Esterase of the alpha-beta hydrolase superfamily
KO64_RS11345	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KO64_RS11365	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KO64_RS11380	COG1396	sequence-specific DNA binding
KO64_RS11390	COG0681	Belongs to the peptidase S26 family
KO64_RS11415	COG4940	Competence protein ComGF
KO64_RS11425	COG4970	Tfp pilus assembly protein FimT
KO64_RS11430	COG4537	Required for transformation and DNA binding
KO64_RS11435	COG1459	type II secretion system
KO64_RS11440	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KO64_RS11445	COG0598	Magnesium transport protein CorA
KO64_RS11450	COG1253	flavin adenine dinucleotide binding
KO64_RS11455	COG1366	Belongs to the anti-sigma-factor antagonist family
KO64_RS11465	COG1393	Belongs to the ArsC family
KO64_RS11475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KO64_RS11485	COG0011	TIGRFAM Protein of
KO64_RS11495	COG2866	Carboxypeptidase
KO64_RS11500	COG1940	carbohydrate kinase activity
KO64_RS11505	COG4483	Protein conserved in bacteria
KO64_RS11510	COG1757	Na H antiporter
KO64_RS11515	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KO64_RS11525	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KO64_RS11530	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KO64_RS11535	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KO64_RS11540	COG0581	inorganic phosphate transmembrane transporter activity
KO64_RS11545	COG0573	inorganic phosphate transmembrane transporter activity
KO64_RS11550	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KO64_RS11555	COG0768	penicillin binding
KO64_RS11560	COG0477	Major facilitator Superfamily
KO64_RS11565	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KO64_RS11570	COG2839	Protein conserved in bacteria
KO64_RS11575	COG5521	maltodextrose utilization protein MalA
KO64_RS11580	COG1388	LysM domain
KO64_RS11590	COG4709	membrane
KO64_RS11595	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
KO64_RS11600	COG0735	belongs to the Fur family
KO64_RS11605	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KO64_RS11620	COG0513	Belongs to the DEAD box helicase family
KO64_RS11635	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KO64_RS11640	COG2384	SAM-dependent methyltransferase
KO64_RS11645	COG2010	Cytochrome c
KO64_RS11650	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KO64_RS11655	COG0358	DNA primase activity
KO64_RS11670	COG0517	IMP dehydrogenase activity
KO64_RS11675	COG0751	glycine-tRNA ligase activity
KO64_RS11690	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KO64_RS11695	COG0295	cytidine deaminase activity
KO64_RS11700	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KO64_RS11710	COG1480	7TM receptor with intracellular HD hydrolase
KO64_RS11715	COG1702	phosphate starvation-inducible protein PhoH
KO64_RS11720	COG0561	phosphatase activity
KO64_RS11735	COG4864	UPF0365 protein
KO64_RS11740	COG1030	water channel activity
KO64_RS11745	COG1610	YqeY-like protein
KO64_RS11755	COG1283	sodium-dependent phosphate transmembrane transporter activity
KO64_RS11760	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KO64_RS11765	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KO64_RS11795	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KO64_RS11810	COG0860	N-Acetylmuramoyl-L-alanine amidase
KO64_RS11825	COG1466	dna polymerase III delta subunit
KO64_RS11835	COG0658	competence protein
KO64_RS11835	COG2333	competence protein COMEC
KO64_RS11840	COG2131	deaminase
KO64_RS11845	COG1596	polysaccharide export
KO64_RS11845	COG1555	photosystem II stabilization
KO64_RS11850	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KO64_RS11855	COG2226	methyltransferase
KO64_RS11860	COG0799	negative regulation of ribosome biogenesis
KO64_RS11865	COG1713	HD superfamily hydrolase involved in NAD metabolism
KO64_RS11875	COG1534	Rna-binding protein
KO64_RS11880	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KO64_RS11885	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KO64_RS11890	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KO64_RS11900	COG2755	lipolytic protein G-D-S-L family
KO64_RS11910	COG0398	Pfam SNARE associated Golgi protein
KO64_RS11940	COG2207	Transcriptional regulator
KO64_RS11940	COG3708	Transcriptional regulator
KO64_RS11950	COG0563	adenylate kinase activity
KO64_RS11955	COG2814	Major facilitator Superfamily
KO64_RS11960	COG0456	acetyltransferase
KO64_RS11965	COG2318	DinB family
KO64_RS11975	COG0561	phosphatase activity
KO64_RS11980	COG0561	phosphatase activity
KO64_RS11990	COG1482	cell wall glycoprotein biosynthetic process
KO64_RS11995	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KO64_RS11995	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KO64_RS11995	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KO64_RS12000	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KO64_RS12000	COG3711	transcriptional antiterminator
KO64_RS12010	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KO64_RS12015	COG0583	DNA-binding transcription factor activity
KO64_RS12020	COG2814	Major facilitator Superfamily
KO64_RS12025	COG2124	cytochrome p450
KO64_RS12025	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KO64_RS12030	COG1309	transcriptional regulator
KO64_RS12035	COG2226	methyltransferase
KO64_RS12040	COG2116	formate transmembrane transporter activity
KO64_RS12045	COG5609	conserved protein (DUF2294)
KO64_RS12050	COG3383	formate dehydrogenase (NAD+) activity
KO64_RS12055	COG2427	Protein of unknown function (DUF1641)
KO64_RS12065	COG0626	cystathionine gamma-synthase activity
KO64_RS12070	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KO64_RS12095	COG0768	penicillin binding
KO64_RS12110	COG0826	peptidase U32
KO64_RS12115	COG0826	peptidase U32
KO64_RS12120	COG4122	O-methyltransferase activity
KO64_RS12125	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KO64_RS12140	COG4472	Bacterial protein of unknown function (DUF965)
KO64_RS12150	COG0628	permease
KO64_RS12155	COG1126	abc transporter atp-binding protein
KO64_RS12160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KO64_RS12165	COG0765	amino acid transport
KO64_RS12170	COG0765	amino acid transport
KO64_RS12180	COG3881	PFAM PRC-barrel domain
KO64_RS12185	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KO64_RS12190	COG0457	Tetratricopeptide repeat
KO64_RS12200	COG1104	cysteine desulfurase activity
KO64_RS12205	COG1959	2 iron, 2 sulfur cluster binding
KO64_RS12210	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KO64_RS12215	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KO64_RS12230	COG4991	sh3 domain protein
KO64_RS12230	COG3103	Sh3 type 3 domain protein
KO64_RS12230	COG0860	N-Acetylmuramoyl-L-alanine amidase
KO64_RS12240	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KO64_RS12250	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KO64_RS12250	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KO64_RS12255	COG5416	Lipopolysaccharide assembly protein A domain
KO64_RS12260	COG0490	domain, Protein
KO64_RS12265	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KO64_RS12265	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KO64_RS12275	COG2244	polysaccharide biosynthetic process
KO64_RS12280	COG2323	membrane
KO64_RS12290	COG1862	Preprotein translocase
KO64_RS12335	COG1388	LysM domain
KO64_RS12345	COG0157	Belongs to the NadC ModD family
KO64_RS12350	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KO64_RS12355	COG1104	cysteine desulfurase activity
KO64_RS12360	COG1827	regulation of RNA biosynthetic process
KO64_RS12365	COG0077	Prephenate dehydratase
KO64_RS12380	COG3290	protein histidine kinase activity
KO64_RS12385	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KO64_RS12390	COG2868	ribosomal protein
KO64_RS12400	COG1994	Peptidase M50
KO64_RS12405	COG0739	heme binding
KO64_RS12410	COG2894	cell division
KO64_RS12420	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KO64_RS12430	COG1077	Cell shape determining protein MreB Mrl
KO64_RS12450	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KO64_RS12455	COG0285	dihydrofolate synthase activity
KO64_RS12460	COG0525	valine-tRNA ligase activity
KO64_RS12470	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KO64_RS12475	COG1388	LysM domain
KO64_RS12485	COG0113	porphobilinogen synthase activity
KO64_RS12490	COG1587	Uroporphyrinogen-III synthase
KO64_RS12500	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KO64_RS12520	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KO64_RS12525	COG0470	DNA polymerase III
KO64_RS12525	COG1067	ATP-dependent peptidase activity
KO64_RS12540	COG0457	Tetratricopeptide repeat
KO64_RS12540	COG1477	protein flavinylation
KO64_RS12555	COG0473	3-isopropylmalate dehydrogenase activity
KO64_RS12570	COG0440	acetolactate synthase activity
KO64_RS12575	COG0028	Belongs to the TPP enzyme family
KO64_RS12600	COG0622	Phosphoesterase
KO64_RS12605	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KO64_RS12615	COG5401	PFAM Sporulation and spore germination
KO64_RS12625	COG1846	Transcriptional regulator
KO64_RS12630	COG2197	response regulator
KO64_RS12635	COG0824	Thioesterase
KO64_RS12640	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KO64_RS12645	COG1053	succinate dehydrogenase
KO64_RS12650	COG2009	succinate dehydrogenase
KO64_RS12655	COG1719	4-vinyl reductase, 4VR
KO64_RS12660	COG0527	aspartate kinase activity
KO64_RS12670	COG3118	belongs to the thioredoxin family
KO64_RS12675	COG3534	alpha-L-arabinofuranosidase
KO64_RS12680	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KO64_RS12685	COG2086	electron transfer activity
KO64_RS12690	COG1024	Enoyl-CoA hydratase
KO64_RS12695	COG1309	transcriptional regulator
KO64_RS12700	COG0318	PFAM AMP-dependent synthetase and ligase
KO64_RS12710	COG3766	membrane
KO64_RS12720	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KO64_RS12720	COG1796	DNA polymerase
KO64_RS12725	COG1286	toxin biosynthetic process
KO64_RS12740	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KO64_RS12740	COG0072	phenylalanine-tRNA ligase activity
KO64_RS12745	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KO64_RS12750	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KO64_RS12760	COG3835	regulator
KO64_RS12765	COG0277	FAD linked oxidase domain protein
KO64_RS12770	COG0247	lactate metabolic process
KO64_RS12775	COG1966	Carbon starvation protein
KO64_RS12780	COG3534	alpha-L-arabinofuranosidase
KO64_RS12785	COG0395	ABC-type sugar transport system, permease component
KO64_RS12790	COG1175	transmembrane transport
KO64_RS12795	COG1653	transport
KO64_RS12805	COG0647	UMP catabolic process
KO64_RS12810	COG0235	Class ii aldolase
KO64_RS12815	COG1069	ribulokinase activity
KO64_RS12820	COG2160	L-arabinose isomerase activity
KO64_RS12825	COG3507	Belongs to the glycosyl hydrolase 43 family
KO64_RS12830	COG1363	Peptidase, m42
KO64_RS12840	COG3326	Membrane
KO64_RS12845	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KO64_RS12855	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KO64_RS12860	COG1346	cytolysis
KO64_RS12865	COG1380	Effector of murein hydrolase LrgA
KO64_RS12870	COG3279	Response regulator of the LytR AlgR family
KO64_RS12875	COG3275	phosphorelay sensor kinase activity
KO64_RS12880	COG1011	Hydrolase
KO64_RS12895	COG0398	Pfam SNARE associated Golgi protein
KO64_RS12900	COG1484	DNA-dependent DNA replication
KO64_RS12905	COG3611	Membrane attachment protein
KO64_RS12920	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KO64_RS12925	COG1733	regulation of RNA biosynthetic process
KO64_RS12930	COG2814	Major facilitator Superfamily
KO64_RS12935	COG0656	L-ascorbic acid biosynthetic process
KO64_RS12940	COG0237	dephospho-CoA kinase activity
KO64_RS12945	COG1971	Probably functions as a manganese efflux pump
KO64_RS12950	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KO64_RS12955	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KO64_RS12955	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KO64_RS12960	COG5002	protein histidine kinase activity
KO64_RS12965	COG0745	RESPONSE REGULATOR receiver
KO64_RS12975	COG0538	isocitrate dehydrogenase activity
KO64_RS12980	COG0372	Belongs to the citrate synthase family
KO64_RS12995	COG0628	permease
KO64_RS13000	COG3030	protein affecting phage T7 exclusion by the F plasmid
KO64_RS13005	COG0469	pyruvate kinase activity
KO64_RS13030	COG0281	malic enzyme
KO64_RS13035	COG0587	DNA-directed DNA polymerase activity
KO64_RS13055	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KO64_RS13065	COG4109	DRTGG domain
KO64_RS13075	COG1028	Short-chain dehydrogenase reductase Sdr
KO64_RS13090	COG0521	Mo-molybdopterin cofactor biosynthetic process
KO64_RS13100	COG0827	DNA restriction-modification system
KO64_RS13105	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KO64_RS13110	COG3874	Sporulation protein YtfJ
KO64_RS13120	COG1714	RDD family
KO64_RS13125	COG0616	signal peptide processing
KO64_RS13130	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KO64_RS13135	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KO64_RS13140	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KO64_RS13155	COG1104	cysteine desulfurase activity
KO64_RS13160	COG1114	Component of the transport system for branched-chain amino acids
KO64_RS13170	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KO64_RS13175	COG1309	transcriptional regulator
KO64_RS13180	COG1956	GAF domain-containing protein
KO64_RS13185	COG2199	diguanylate cyclase activity
KO64_RS13185	COG2203	Gaf domain
KO64_RS13195	COG1012	belongs to the aldehyde dehydrogenase family
KO64_RS13225	COG1017	nitric oxide dioxygenase activity
KO64_RS13225	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KO64_RS13235	COG0693	protein deglycase activity
KO64_RS13250	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KO64_RS13255	COG1378	Sugar-specific transcriptional regulator TrmB
KO64_RS13275	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KO64_RS13280	COG0454	-acetyltransferase
KO64_RS13285	COG0517	IMP dehydrogenase activity
KO64_RS13290	COG0123	including yeast histone deacetylase and acetoin utilization protein
KO64_RS13295	COG1360	Flagellar Motor Protein
KO64_RS13300	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KO64_RS13305	COG1609	Transcriptional regulator
KO64_RS13310	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KO64_RS13310	COG1605	Chorismate mutase
KO64_RS13315	COG3118	belongs to the thioredoxin family
KO64_RS13320	COG4980	gas vesicle protein
KO64_RS13325	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KO64_RS13335	COG1674	ftsk spoiiie
KO64_RS13340	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KO64_RS13350	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KO64_RS13360	COG1363	Peptidase, m42
KO64_RS13365	COG5584	Small secreted protein
KO64_RS13370	COG0281	malic enzyme
KO64_RS13375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KO64_RS13390	COG0510	thiamine kinase activity
KO64_RS13395	COG1597	lipid kinase activity
KO64_RS13405	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KO64_RS13410	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KO64_RS13415	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KO64_RS13420	COG2252	PERMEase
KO64_RS13425	COG4473	ABC transporter
KO64_RS13430	COG1131	(ABC) transporter
KO64_RS13435	COG1349	DNA-binding transcription factor activity
KO64_RS13440	COG1187	pseudouridine synthase activity
KO64_RS13445	COG2244	polysaccharide biosynthetic process
KO64_RS13450	COG2081	HI0933 family
KO64_RS13455	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KO64_RS13465	COG1609	Transcriptional regulator
KO64_RS13470	COG1653	transport
KO64_RS13475	COG1175	transmembrane transport
KO64_RS13480	COG0395	ABC-type sugar transport system, permease component
KO64_RS13485	COG1486	melibiose metabolic process
KO64_RS13495	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KO64_RS13510	COG1366	Belongs to the anti-sigma-factor antagonist family
KO64_RS13510	COG2202	Pas domain
KO64_RS13515	COG2814	Major facilitator Superfamily
KO64_RS13520	COG5522	Integral membrane protein (intg_mem_TP0381)
KO64_RS13525	COG0577	efflux transmembrane transporter activity
KO64_RS13530	COG1136	(ABC) transporter
KO64_RS13535	COG2205	protein histidine kinase activity
KO64_RS13540	COG0745	RESPONSE REGULATOR receiver
KO64_RS13545	COG0577	efflux transmembrane transporter activity
KO64_RS13550	COG1136	(ABC) transporter
KO64_RS13570	COG1131	(ABC) transporter
KO64_RS13575	COG1725	Transcriptional regulator
KO64_RS13585	COG0640	Transcriptional regulator
KO64_RS13590	COG0477	Major facilitator Superfamily
KO64_RS13595	COG1242	4 iron, 4 sulfur cluster binding
KO64_RS13600	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KO64_RS13610	COG0584	glycerophosphoryl diester phosphodiesterase
KO64_RS13620	COG2267	carboxylic ester hydrolase activity
KO64_RS13625	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KO64_RS13630	COG1113	amino acid transport
KO64_RS13635	COG0367	asparagine synthase
KO64_RS13655	COG1506	peptidase
KO64_RS13660	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KO64_RS13665	COG1116	anion transmembrane transporter activity
KO64_RS13670	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KO64_RS13675	COG0494	nUDIX hydrolase
KO64_RS13680	COG4824	toxin secretion phage lysis holin
KO64_RS13685	COG0783	Belongs to the Dps family
KO64_RS13710	COG0288	reversible hydration of carbon dioxide
KO64_RS13720	COG1271	oxidase subunit
KO64_RS13725	COG1294	oxidase, subunit
KO64_RS13735	COG4948	Mandelate Racemase Muconate Lactonizing
KO64_RS13745	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KO64_RS13750	COG0596	Alpha beta hydrolase
KO64_RS13760	COG1169	isochorismate synthase
KO64_RS13765	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KO64_RS13770	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
KO64_RS13775	COG2801	Transposase and inactivated derivatives
KO64_RS13905	COG3859	Proton-coupled thiamine transporter YuaJ
KO64_RS13910	COG2268	Band 7 protein
KO64_RS13915	COG1585	Membrane protein implicated in regulation of membrane protease activity
KO64_RS13920	COG2318	DinB family
KO64_RS13930	COG1454	alcohol dehydrogenase
KO64_RS13935	COG1012	belongs to the aldehyde dehydrogenase family
KO64_RS13940	COG1510	regulation of RNA biosynthetic process
KO64_RS13950	COG0569	domain protein
KO64_RS13955	COG1705	Flagellar rod assembly protein muramidase FlgJ
KO64_RS13960	COG1017	nitric oxide dioxygenase activity
KO64_RS13960	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KO64_RS14005	COG1196	nuclear chromosome segregation
KO64_RS14005	COG0739	heme binding
KO64_RS14005	COG0741	lytic transglycosylase activity
KO64_RS14010	COG0741	lytic transglycosylase activity
KO64_RS14010	COG0739	heme binding
KO64_RS14010	COG1196	nuclear chromosome segregation
KO64_RS14030	COG5444	nuclease activity
KO64_RS14040	COG5632	N-Acetylmuramoyl-L-alanine amidase
KO64_RS14040	COG3409	Peptidoglycan-binding domain 1 protein
KO64_RS14040	COG1388	LysM domain
KO64_RS14045	COG4824	toxin secretion phage lysis holin
KO64_RS14145	COG5484	DNA packaging
KO64_RS14150	COG3677	Transposase
KO64_RS14190	COG1484	DNA-dependent DNA replication
KO64_RS14195	COG3935	DnaD domain protein
KO64_RS14250	COG3620	sequence-specific DNA binding
KO64_RS14260	COG2856	Zn peptidase
KO64_RS14265	COG0582	viral genome integration into host DNA
KO64_RS14280	COG0628	permease
KO64_RS14285	COG0673	inositol 2-dehydrogenase activity
KO64_RS14290	COG0693	protein deglycase activity
KO64_RS14295	COG0840	transmembrane signaling receptor activity
KO64_RS14300	COG0840	transmembrane signaling receptor activity
KO64_RS14305	COG0840	transmembrane signaling receptor activity
KO64_RS14310	COG0840	transmembrane signaling receptor activity
KO64_RS14325	COG2070	2-Nitropropane dioxygenase
KO64_RS14330	COG0432	Pfam Uncharacterised protein family UPF0047
KO64_RS14335	COG0366	Alpha amylase catalytic
KO64_RS14340	COG1253	flavin adenine dinucleotide binding
KO64_RS14345	COG2738	Putative neutral zinc metallopeptidase
KO64_RS14360	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KO64_RS14390	COG1335	isochorismatase
KO64_RS14395	COG1979	alcohol dehydrogenase
KO64_RS14400	COG1979	alcohol dehydrogenase
KO64_RS14405	COG2155	Conserved Protein
KO64_RS14410	COG1098	S1 RNA binding domain
KO64_RS14415	COG0436	Aminotransferase
KO64_RS14420	COG1522	sequence-specific DNA binding
KO64_RS14425	COG2267	carboxylic ester hydrolase activity
KO64_RS14435	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KO64_RS14440	COG2205	protein histidine kinase activity
KO64_RS14450	COG5018	Exonuclease
KO64_RS14455	COG2814	Major facilitator Superfamily
KO64_RS14460	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KO64_RS14465	COG3011	Protein conserved in bacteria
KO64_RS14475	COG3290	protein histidine kinase activity
KO64_RS14480	COG4565	transcriptional regulatory protein
KO64_RS14485	COG1744	ABC transporter substrate-binding protein PnrA-like
KO64_RS14490	COG3845	ABC transporter
KO64_RS14495	COG4603	Belongs to the binding-protein-dependent transport system permease family
KO64_RS14500	COG1079	Belongs to the binding-protein-dependent transport system permease family
KO64_RS14510	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KO64_RS14510	COG2111	Na H antiporter
KO64_RS14515	COG2111	Na H antiporter
KO64_RS14520	COG1006	Multisubunit Na H antiporter MnhC subunit
KO64_RS14525	COG0651	ATP synthesis coupled electron transport
KO64_RS14530	COG1863	multisubunit Na H antiporter MnhE subunit
KO64_RS14535	COG2212	antiporter activity
KO64_RS14540	COG1320	monovalent cation:proton antiporter activity
KO64_RS14545	COG2050	protein possibly involved in aromatic compounds catabolism
KO64_RS14550	COG2197	response regulator
KO64_RS14565	COG0142	geranyltranstransferase activity
KO64_RS14585	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KO64_RS14590	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KO64_RS14595	COG1335	isochorismatase
KO64_RS14600	COG5506	Protein of unknown function (DUF1694)
KO64_RS14615	COG0628	permease
KO64_RS14625	COG1418	mRNA catabolic process
KO64_RS14630	COG1028	Short-chain dehydrogenase reductase Sdr
KO64_RS14640	COG1511	domain protein
KO64_RS14645	COG1674	ftsk spoiiie
KO64_RS14645	COG0433	COG0433 Predicted ATPase
KO64_RS14650	COG4499	WXG100 protein secretion system (Wss), protein YukC
KO64_RS14655	COG5417	Belongs to the EsaB family
KO64_RS14660	COG4842	Belongs to the WXG100 family
KO64_RS14665	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KO64_RS14665	COG2508	Transcriptional regulator
KO64_RS14670	COG0686	Belongs to the AlaDH PNT family
KO64_RS14675	COG5634	Uncharacterized conserved protein (DUF2278)
KO64_RS14680	COG3251	PFAM MbtH domain protein
KO64_RS14685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KO64_RS14690	COG3433	isochorismatase activity
KO64_RS14690	COG1535	isochorismatase
KO64_RS14695	COG1021	2,3-dihydroxybenzoate-AMP ligase
KO64_RS14700	COG1169	isochorismate synthase
KO64_RS14705	COG1028	Short-chain dehydrogenase reductase Sdr
KO64_RS14710	COG2819	hydrolase of the alpha beta superfamily
KO64_RS14715	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KO64_RS14720	COG1268	BioY protein
KO64_RS14725	COG2056	Na+-H+ antiporter family
KO64_RS14735	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KO64_RS14740	COG3584	3D domain protein
KO64_RS14750	COG1252	NADH dehydrogenase
KO64_RS14780	COG1131	(ABC) transporter
KO64_RS14800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KO64_RS14805	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
KO64_RS14810	COG0316	Belongs to the HesB IscA family
KO64_RS14820	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KO64_RS14830	COG1252	NADH dehydrogenase
KO64_RS14835	COG4837	Protein of unknown function (DUF1462)
KO64_RS14840	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KO64_RS14845	COG1506	peptidase
KO64_RS14845	COG0823	Involved in the tonB-independent uptake of proteins
KO64_RS14845	COG4946	Tricorn protease homolog
KO64_RS14855	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KO64_RS14860	COG0460	homoserine dehydrogenase
KO64_RS14865	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KO64_RS14870	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KO64_RS14875	COG0647	UMP catabolic process
KO64_RS14880	COG2445	Protein of unknown function DUF86
KO64_RS14885	COG4470	Protein conserved in bacteria
KO64_RS14895	COG0739	heme binding
KO64_RS14905	COG0737	Belongs to the 5'-nucleotidase family
KO64_RS14910	COG0730	response to heat
KO64_RS14915	COG1801	Protein of unknown function DUF72
KO64_RS14930	COG2508	Transcriptional regulator
KO64_RS14940	COG2801	Transposase and inactivated derivatives
KO64_RS14960	COG2814	Major facilitator Superfamily
KO64_RS14965	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KO64_RS14970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KO64_RS14975	COG2356	endonuclease I
KO64_RS14980	COG3842	ATPase activity
KO64_RS14985	COG2188	Transcriptional regulator
KO64_RS14990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KO64_RS14995	COG0395	ABC-type sugar transport system, permease component
KO64_RS15000	COG1175	transmembrane transport
KO64_RS15005	COG1653	transport
KO64_RS15010	COG2222	sugar isomerase
KO64_RS15015	COG0789	Transcriptional regulator
KO64_RS15040	COG0322	excinuclease ABC activity
KO64_RS15045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KO64_RS15050	COG2226	methyltransferase
KO64_RS15060	COG3409	Peptidoglycan-binding domain 1 protein
KO64_RS15065	COG0719	Fe-S assembly protein
KO64_RS15070	COG0822	iron-sulfur transferase activity
KO64_RS15075	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KO64_RS15080	COG0719	Fe-S assembly protein
KO64_RS15085	COG0396	ATPase activity
KO64_RS15090	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KO64_RS15095	COG1464	Belongs to the NlpA lipoprotein family
KO64_RS15100	COG2011	ABC-type metal ion transport system permease component
KO64_RS15105	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KO64_RS15115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KO64_RS15120	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KO64_RS15135	COG1393	Belongs to the ArsC family
KO64_RS15140	COG1960	acyl-CoA dehydrogenase activity
KO64_RS15145	COG0183	Belongs to the thiolase family
KO64_RS15150	COG1250	3-hydroxyacyl-CoA dehydrogenase
KO64_RS15150	COG1024	Enoyl-CoA hydratase
KO64_RS15170	COG5577	PFAM Coat F domain
KO64_RS15175	COG1846	Transcriptional regulator
KO64_RS15180	COG0477	Major facilitator Superfamily
KO64_RS15185	COG0583	DNA-binding transcription factor activity
KO64_RS15205	COG1120	ATPase activity
KO64_RS15220	COG1028	Short-chain dehydrogenase reductase Sdr
KO64_RS15225	COG0783	Belongs to the Dps family
KO64_RS15230	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KO64_RS15235	COG0745	RESPONSE REGULATOR receiver
KO64_RS15240	COG2205	protein histidine kinase activity
KO64_RS15240	COG2770	Histidine kinase
KO64_RS15245	COG1309	transcriptional regulator
KO64_RS15250	COG0114	fumarate hydratase activity
KO64_RS15260	COG0697	spore germination
KO64_RS15265	COG0814	amino acid
KO64_RS15275	COG2197	response regulator
KO64_RS15280	COG4585	Histidine kinase
KO64_RS15285	COG4758	membrane
KO64_RS15290	COG3595	metallopeptidase activity
KO64_RS15295	COG1842	Phage shock protein A
KO64_RS15300	COG4758	membrane
KO64_RS15305	COG2814	Major facilitator Superfamily
KO64_RS15310	COG2096	Adenosyltransferase
KO64_RS15315	COG1120	ATPase activity
KO64_RS15320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KO64_RS15325	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KO64_RS15330	COG1028	Short-chain dehydrogenase reductase Sdr
KO64_RS15335	COG3386	PFAM SMP-30 Gluconolaconase
KO64_RS15340	COG2205	protein histidine kinase activity
KO64_RS15345	COG0745	RESPONSE REGULATOR receiver
KO64_RS15355	COG1191	sigma factor activity
KO64_RS15360	COG2140	Oxalate decarboxylase
KO64_RS15370	COG1120	ATPase activity
KO64_RS15375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KO64_RS15380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KO64_RS15385	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KO64_RS15390	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KO64_RS15395	COG0531	amino acid
KO64_RS15410	COG1988	membrane-bound metal-dependent
KO64_RS15415	COG1368	sulfuric ester hydrolase activity
KO64_RS15420	COG1910	domain protein
KO64_RS15425	COG0725	ABC transporter, periplasmic molybdate-binding protein
KO64_RS15430	COG4149	molybdate abc transporter
KO64_RS15435	COG2197	response regulator
KO64_RS15440	COG3850	Histidine kinase
KO64_RS15445	COG1131	(ABC) transporter
KO64_RS15455	COG0842	Transport permease protein
KO64_RS15460	COG0656	L-ascorbic acid biosynthetic process
KO64_RS15485	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KO64_RS15490	COG3973	AAA domain
KO64_RS15495	COG2860	membrane
KO64_RS15505	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KO64_RS15510	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KO64_RS15515	COG2217	Heavy metal translocating P-type atpase
KO64_RS15520	COG2217	Heavy metal translocating P-type atpase
KO64_RS15525	COG2608	mercury ion transmembrane transporter activity
KO64_RS15530	COG1937	Protein conserved in bacteria
KO64_RS15535	COG0673	inositol 2-dehydrogenase activity
KO64_RS15550	COG2814	Major facilitator Superfamily
KO64_RS15565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KO64_RS15570	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KO64_RS15575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KO64_RS15580	COG1126	abc transporter atp-binding protein
KO64_RS15585	COG0765	amino acid transport
KO64_RS15590	COG0765	amino acid transport
KO64_RS15595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KO64_RS15600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KO64_RS15605	COG0454	-acetyltransferase
KO64_RS15610	COG0583	DNA-binding transcription factor activity
KO64_RS15615	COG1028	Short-chain dehydrogenase reductase Sdr
KO64_RS15620	COG2732	(Barnase) inhibitor
KO64_RS15640	COG0557	exoribonuclease II activity
KO64_RS15645	COG1647	Serine aminopeptidase, S33
KO64_RS15650	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KO64_RS15655	COG1476	TRANSCRIPTIONal
KO64_RS15660	COG1396	sequence-specific DNA binding
KO64_RS15665	COG1396	sequence-specific DNA binding
KO64_RS15670	COG1733	regulation of RNA biosynthetic process
KO64_RS15695	COG1131	(ABC) transporter
KO64_RS15700	COG1174	glycine betaine transport
KO64_RS15705	COG1732	Glycine betaine
KO64_RS15710	COG1174	glycine betaine transport
KO64_RS15715	COG1125	glycine betaine transport
KO64_RS15715	COG0517	IMP dehydrogenase activity
KO64_RS15720	COG1510	regulation of RNA biosynthetic process
KO64_RS15725	COG1174	glycine betaine transport
KO64_RS15730	COG1732	Glycine betaine
KO64_RS15735	COG1174	glycine betaine transport
KO64_RS15740	COG0517	IMP dehydrogenase activity
KO64_RS15740	COG1125	glycine betaine transport
KO64_RS15750	COG2095	MarC family integral membrane protein
KO64_RS15765	COG1174	glycine betaine transport
KO64_RS15770	COG1125	glycine betaine transport
KO64_RS15770	COG0517	IMP dehydrogenase activity
KO64_RS15775	COG1510	regulation of RNA biosynthetic process
KO64_RS15780	COG1174	glycine betaine transport
KO64_RS15785	COG1732	Glycine betaine
KO64_RS15790	COG1174	glycine betaine transport
KO64_RS15795	COG0517	IMP dehydrogenase activity
KO64_RS15795	COG1125	glycine betaine transport
KO64_RS15800	COG1510	regulation of RNA biosynthetic process
KO64_RS15805	COG2095	MarC family integral membrane protein
KO64_RS15810	COG3064	Membrane
KO64_RS15815	COG4640	response to antibiotic
KO64_RS15820	COG0456	acetyltransferase
KO64_RS15835	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KO64_RS15855	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KO64_RS15860	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KO64_RS15870	COG2234	aminopeptidase activity
KO64_RS15890	COG0126	phosphoglycerate kinase activity
KO64_RS15900	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KO64_RS15905	COG2390	Transcriptional regulator
KO64_RS15910	COG2814	Major facilitator Superfamily
KO64_RS15915	COG1609	Transcriptional regulator
KO64_RS15920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KO64_RS15930	COG0583	DNA-binding transcription factor activity
KO64_RS15935	COG0697	spore germination
KO64_RS15940	COG2801	Transposase and inactivated derivatives
KO64_RS15950	COG1113	amino acid transport
KO64_RS15960	COG1609	Transcriptional regulator
KO64_RS15970	COG0561	phosphatase activity
KO64_RS15975	COG1737	Transcriptional regulator
KO64_RS15980	COG1070	Carbohydrate kinase
KO64_RS16010	COG2186	Transcriptional regulator
KO64_RS16015	COG1620	l-lactate permease
KO64_RS16020	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KO64_RS16030	COG5039	Polysaccharide pyruvyl transferase
KO64_RS16035	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KO64_RS16040	COG0110	maltose O-acetyltransferase activity
KO64_RS16045	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KO64_RS16050	COG2244	polysaccharide biosynthetic process
KO64_RS16055	COG1216	Glycosyl transferase, family 2
KO64_RS16060	COG5039	Polysaccharide pyruvyl transferase
KO64_RS16065	COG1216	Glycosyl transferase, family 2
KO64_RS16075	COG0438	transferase activity, transferring glycosyl groups
KO64_RS16080	COG1215	transferase activity, transferring glycosyl groups
KO64_RS16085	COG0438	transferase activity, transferring glycosyl groups
KO64_RS16090	COG1086	Polysaccharide biosynthesis protein
KO64_RS16095	COG0489	protein tyrosine kinase activity
KO64_RS16100	COG3944	biosynthesis protein
KO64_RS16105	COG1396	sequence-specific DNA binding
KO64_RS16110	COG2272	Belongs to the type-B carboxylesterase lipase family
KO64_RS16115	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KO64_RS16120	COG2364	Membrane
KO64_RS16125	COG0456	acetyltransferase
KO64_RS16130	COG3479	Phenolic acid decarboxylase
KO64_RS16175	COG2223	nitrite transmembrane transporter activity
KO64_RS16180	COG1609	Transcriptional regulator
KO64_RS16190	COG0583	DNA-binding transcription factor activity
KO64_RS16195	COG2828	Protein conserved in bacteria
KO64_RS16200	COG2814	Major facilitator Superfamily
KO64_RS16200	COG0477	Major facilitator Superfamily
KO64_RS16205	COG1611	Belongs to the LOG family
KO64_RS16210	COG1694	Mazg nucleotide pyrophosphohydrolase
KO64_RS16215	COG0659	secondary active sulfate transmembrane transporter activity
KO64_RS16220	COG0288	reversible hydration of carbon dioxide
KO64_RS16230	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KO64_RS16235	COG4290	ribonuclease
KO64_RS16240	COG2162	N-hydroxyarylamine O-acetyltransferase activity
KO64_RS16245	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KO64_RS16255	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KO64_RS16265	COG1051	belongs to the nudix hydrolase family
KO64_RS16270	COG0492	ferredoxin-NADP+ reductase activity
KO64_RS16275	COG3883	PFAM NLP P60 protein
KO64_RS16275	COG0791	NLP P60 protein
KO64_RS16280	COG0457	Tetratricopeptide repeat
KO64_RS16285	COG5002	protein histidine kinase activity
KO64_RS16290	COG0745	RESPONSE REGULATOR receiver
KO64_RS16295	COG1132	(ABC) transporter
KO64_RS16300	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KO64_RS16300	COG0140	phosphoribosyl-ATP diphosphatase activity
KO64_RS16325	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KO64_RS16340	COG4990	cell redox homeostasis
KO64_RS16345	COG0110	maltose O-acetyltransferase activity
KO64_RS16365	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KO64_RS16375	COG2188	Transcriptional regulator
KO64_RS16380	COG1309	transcriptional regulator
KO64_RS16385	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KO64_RS16390	COG1950	PFAM Membrane protein of
KO64_RS16395	COG1983	PspC domain protein
KO64_RS16400	COG3595	metallopeptidase activity
KO64_RS16415	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KO64_RS16425	COG4897	Protein conserved in bacteria
KO64_RS16430	COG0574	Belongs to the PEP-utilizing enzyme family
KO64_RS16430	COG3848	Pyruvate phosphate dikinase
KO64_RS16435	COG1309	transcriptional regulator
KO64_RS16440	COG2814	Major facilitator Superfamily
KO64_RS16455	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KO64_RS16465	COG0793	Belongs to the peptidase S41A family
KO64_RS16465	COG3409	Peptidoglycan-binding domain 1 protein
KO64_RS16470	COG3420	alginic acid biosynthetic process
KO64_RS16475	COG2177	Part of the ABC transporter FtsEX involved in
KO64_RS16480	COG2884	Cell division ATP-binding protein ftsE
KO64_RS16485	COG2010	Cytochrome c
KO64_RS16490	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KO64_RS16495	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KO64_RS16505	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KO64_RS16520	COG1516	flagellar protein fliS
KO64_RS16525	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KO64_RS16530	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KO64_RS16550	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KO64_RS16555	COG4786	Flagellar basal body rod
KO64_RS16555	COG1256	bacterial-type flagellum assembly
KO64_RS16560	COG3418	PFAM FlgN family protein
KO64_RS16565	COG2747	anti-sigma28 factor FlgM
KO64_RS16575	COG1040	competence protein
KO64_RS16585	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KO64_RS16590	COG1307	EDD domain protein, DegV family
KO64_RS16595	COG2197	response regulator
KO64_RS16600	COG4585	Histidine kinase
KO64_RS16605	COG1739	Uncharacterized protein family UPF0029
KO64_RS16610	COG1316	TRANSCRIPTIONal
KO64_RS16615	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KO64_RS16620	COG0438	transferase activity, transferring glycosyl groups
KO64_RS16625	COG1215	transferase activity, transferring glycosyl groups
KO64_RS16630	COG3206	protein involved in exopolysaccharide biosynthesis
KO64_RS16635	COG3307	-O-antigen
KO64_RS16640	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KO64_RS16645	COG0438	transferase activity, transferring glycosyl groups
KO64_RS16645	COG0297	glycogen (starch) synthase activity
KO64_RS16650	COG2244	polysaccharide biosynthetic process
KO64_RS16660	COG2247	cell wall binding repeat
KO64_RS16660	COG0860	N-Acetylmuramoyl-L-alanine amidase
KO64_RS16665	COG2385	sporulation resulting in formation of a cellular spore
KO64_RS16665	COG2247	cell wall binding repeat
KO64_RS16675	COG1316	TRANSCRIPTIONal
KO64_RS16680	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KO64_RS16685	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KO64_RS16690	COG1134	teichoic acid transport
KO64_RS16695	COG1682	transport, permease protein
KO64_RS16700	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KO64_RS16710	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KO64_RS16715	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
KO64_RS16720	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KO64_RS16725	COG4193	domain, Protein
KO64_RS16730	COG1482	cell wall glycoprotein biosynthetic process
KO64_RS16735	COG0697	spore germination
KO64_RS16740	COG0814	amino acid
KO64_RS16750	COG1215	transferase activity, transferring glycosyl groups
KO64_RS16755	COG2814	Major facilitator Superfamily
KO64_RS16760	COG1316	TRANSCRIPTIONal
KO64_RS16765	COG0561	phosphatase activity
KO64_RS16770	COG2433	Pfam Transposase IS66
KO64_RS16775	COG0791	NLP P60 protein
KO64_RS16790	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KO64_RS16795	COG0697	spore germination
KO64_RS16800	COG0814	amino acid
KO64_RS16810	COG1609	Transcriptional regulator
KO64_RS16815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KO64_RS16825	COG1129	ABC transporter
KO64_RS16830	COG1172	Belongs to the binding-protein-dependent transport system permease family
KO64_RS16835	COG1879	ABC-type sugar transport system periplasmic component
KO64_RS16840	COG3103	Sh3 type 3 domain protein
KO64_RS16845	COG2249	NAD(P)H dehydrogenase (quinone) activity
KO64_RS16850	COG3527	Alpha-acetolactate decarboxylase
KO64_RS16855	COG0028	Belongs to the TPP enzyme family
KO64_RS16860	COG0583	DNA-binding transcription factor activity
KO64_RS16865	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KO64_RS16880	COG5337	Spore coat protein CotH
KO64_RS16890	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KO64_RS16900	COG0405	Gamma-glutamyltransferase
KO64_RS16905	COG1522	sequence-specific DNA binding
KO64_RS16910	COG2059	Chromate
KO64_RS16915	COG2059	Chromate
KO64_RS16930	COG5444	nuclease activity
KO64_RS16945	COG3878	Protein conserved in bacteria
KO64_RS16950	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KO64_RS16955	COG4464	protein tyrosine phosphatase activity
KO64_RS16960	COG0489	protein tyrosine kinase activity
KO64_RS16965	COG3944	biosynthesis protein
KO64_RS16970	COG4715	Zinc finger, swim domain protein
KO64_RS16975	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KO64_RS16980	COG0561	phosphatase activity
KO64_RS16985	COG1349	DNA-binding transcription factor activity
KO64_RS16990	COG0629	single-stranded DNA binding
KO64_RS17015	COG0457	Tetratricopeptide repeat
KO64_RS17020	COG4786	Flagellar basal body rod
KO64_RS17025	COG4786	Flagellar basal body rod
KO64_RS17030	COG1077	Cell shape determining protein MreB Mrl
KO64_RS17035	COG1609	Transcriptional regulator
KO64_RS17040	COG1846	Transcriptional regulator
KO64_RS17045	COG2814	Major facilitator Superfamily
KO64_RS17050	COG1953	Uracil, thiamine, allantoin
KO64_RS17055	COG0477	Major facilitator Superfamily
KO64_RS17060	COG1335	isochorismatase
KO64_RS17065	COG0004	ammonium transporteR
KO64_RS17070	COG0347	Belongs to the P(II) protein family
KO64_RS17075	COG0772	Belongs to the SEDS family
KO64_RS17080	COG0671	phosphoesterase, PA-phosphatase related
KO64_RS17090	COG0739	heme binding
KO64_RS17095	COG1247	-acetyltransferase
KO64_RS17110	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KO64_RS17125	COG0726	polysaccharide deacetylase
KO64_RS17135	COG1959	2 iron, 2 sulfur cluster binding
KO64_RS17150	COG0831	urea catabolic process
KO64_RS17155	COG3237	CsbD-like
KO64_RS17160	COG1994	Peptidase M50
KO64_RS17165	COG0457	Tetratricopeptide repeat
KO64_RS17175	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KO64_RS17180	COG2304	oxidoreductase activity
KO64_RS17185	COG2304	oxidoreductase activity
KO64_RS17190	COG2385	sporulation resulting in formation of a cellular spore
KO64_RS17195	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KO64_RS17205	COG4836	Membrane
KO64_RS17275	COG0698	ribose 5-phosphate isomerase
KO64_RS17280	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KO64_RS17290	COG0009	L-threonylcarbamoyladenylate synthase
KO64_RS17295	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KO64_RS17315	COG2890	protein-(glutamine-N5) methyltransferase activity
KO64_RS17320	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KO64_RS17325	COG0346	lactoylglutathione lyase activity
KO64_RS17330	COG0789	Transcriptional regulator
KO64_RS17335	COG0679	Auxin Efflux Carrier
KO64_RS17340	COG0281	malic enzyme
KO64_RS17355	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KO64_RS17360	COG1494	fructose-1,6-bisphosphatase
KO64_RS17365	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KO64_RS17380	COG0191	fructose-bisphosphate aldolase activity
KO64_RS17385	COG2204	response regulator
KO64_RS17390	COG4821	SIS domain
KO64_RS17405	COG0247	lactate metabolic process
KO64_RS17405	COG2181	nitrate reductase activity
KO64_RS17410	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KO64_RS17425	COG1132	(ABC) transporter
KO64_RS17430	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KO64_RS17440	COG2181	nitrate reductase activity
KO64_RS17445	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KO64_RS17450	COG1140	nitrate reductase beta subunit
KO64_RS17455	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KO64_RS17460	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KO64_RS17470	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KO64_RS17475	COG2223	nitrite transmembrane transporter activity
KO64_RS17485	COG4506	Protein conserved in bacteria
KO64_RS17495	COG3391	amine dehydrogenase activity
KO64_RS17500	COG3391	amine dehydrogenase activity
KO64_RS17505	COG0457	Tetratricopeptide repeat
KO64_RS17550	COG0010	Belongs to the arginase family
KO64_RS17555	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KO64_RS17560	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KO64_RS17575	COG1994	Peptidase M50
KO64_RS17580	COG1942	4-Oxalocrotonate Tautomerase
KO64_RS17585	COG1846	Transcriptional regulator
KO64_RS17590	COG0531	amino acid
KO64_RS17595	COG3465	dGTPase activity
KO64_RS17600	COG1078	dGTPase activity
KO64_RS17615	COG1695	Transcriptional regulator
KO64_RS17625	COG1131	(ABC) transporter
KO64_RS17630	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KO64_RS17660	COG0583	DNA-binding transcription factor activity
KO64_RS17665	COG2855	membrane
KO64_RS17670	COG0280	phosphate acetyltransferase
KO64_RS17680	COG1028	Short-chain dehydrogenase reductase Sdr
KO64_RS17685	COG0436	Aminotransferase
KO64_RS17715	COG2814	Major facilitator Superfamily
KO64_RS17720	COG2814	Major facilitator Superfamily
KO64_RS17725	COG0833	amino acid
KO64_RS17730	COG4187	Peptidase family M20/M25/M40
KO64_RS17735	COG1012	belongs to the aldehyde dehydrogenase family
KO64_RS17740	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KO64_RS17750	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
KO64_RS17755	COG1091	dTDP-4-dehydrorhamnose reductase activity
KO64_RS17760	COG1088	dTDP-glucose 4,6-dehydratase activity
KO64_RS17765	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KO64_RS17770	COG3980	spore coat polysaccharide biosynthesis protein
KO64_RS17775	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
KO64_RS17780	COG2089	acid synthase
KO64_RS17785	COG0456	acetyltransferase
KO64_RS17790	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KO64_RS17795	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KO64_RS17800	COG0463	Glycosyl transferase, family 2
KO64_RS17810	COG2363	Small membrane protein
KO64_RS17815	COG2233	PERMEase
KO64_RS17830	COG1216	Glycosyl transferase, family 2
KO64_RS17845	COG1695	Transcriptional regulator
KO64_RS17850	COG0351	phosphomethylpyrimidine kinase
KO64_RS17860	COG1621	beta-fructofuranosidase activity
KO64_RS17865	COG1263	PTS System
KO64_RS17865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KO64_RS17870	COG3711	transcriptional antiterminator
KO64_RS17880	COG1404	Belongs to the peptidase S8 family
KO64_RS17885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KO64_RS17890	COG0778	Nitroreductase
KO64_RS17895	COG0772	Belongs to the SEDS family
KO64_RS17900	COG0454	-acetyltransferase
KO64_RS17920	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KO64_RS17925	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KO64_RS17930	COG2261	transglycosylase associated protein
KO64_RS17935	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
KO64_RS17940	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KO64_RS17945	COG2246	polysaccharide biosynthetic process
KO64_RS17950	COG1309	transcriptional regulator
KO64_RS17970	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KO64_RS17975	COG2837	iron assimilation
KO64_RS17980	COG2822	iron ion transport
KO64_RS17995	COG0583	DNA-binding transcription factor activity
KO64_RS18005	COG1346	cytolysis
KO64_RS18010	COG4895	conserved protein (DUF2196)
KO64_RS18015	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KO64_RS18020	COG0346	lactoylglutathione lyase activity
KO64_RS18025	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KO64_RS18030	COG1404	Belongs to the peptidase S8 family
KO64_RS18035	COG1442	glycosyl transferase family 8
KO64_RS18045	COG2357	RelA SpoT domain protein
KO64_RS18050	COG1575	Belongs to the MenA family. Type 1 subfamily
KO64_RS18065	COG1696	Membrane protein involved in D-alanine export
KO64_RS18075	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KO64_RS18080	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KO64_RS18085	COG1486	melibiose metabolic process
KO64_RS18090	COG1447	Phosphotransferase system cellobiose-specific component IIA
KO64_RS18095	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KO64_RS18100	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KO64_RS18105	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KO64_RS18105	COG3711	transcriptional antiterminator
KO64_RS18115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KO64_RS18120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KO64_RS18130	COG0640	Transcriptional regulator
KO64_RS18135	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KO64_RS18145	COG1447	Phosphotransferase system cellobiose-specific component IIA
KO64_RS18150	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KO64_RS18155	COG2723	6-phospho-beta-galactosidase activity
KO64_RS18160	COG1940	carbohydrate kinase activity
KO64_RS18165	COG1482	cell wall glycoprotein biosynthetic process
KO64_RS18175	COG0753	catalase activity
KO64_RS18180	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KO64_RS18185	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KO64_RS18190	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KO64_RS18195	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KO64_RS18200	COG4988	ABC transporter
KO64_RS18205	COG1294	oxidase, subunit
KO64_RS18210	COG1271	oxidase subunit
KO64_RS18215	COG3493	citrate carrier protein
KO64_RS18220	COG0726	polysaccharide deacetylase
KO64_RS18225	COG3842	ATPase activity
KO64_RS18230	COG2508	Transcriptional regulator
KO64_RS18235	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KO64_RS18245	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KO64_RS18255	COG4894	glucomannan catabolic process
KO64_RS18260	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KO64_RS18265	COG0500	methyltransferase
KO64_RS18270	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KO64_RS18285	COG0753	catalase activity
KO64_RS18285	COG0693	protein deglycase activity
KO64_RS18290	COG2851	Citrate transporter
KO64_RS18295	COG2273	Hydrolase Family 16
KO64_RS18300	COG3711	transcriptional antiterminator
KO64_RS18305	COG2270	Major facilitator Superfamily
KO64_RS18310	COG0513	Belongs to the DEAD box helicase family
KO64_RS18370	COG3209	COG3209 Rhs family protein
KO64_RS18380	COG0697	spore germination
KO64_RS18385	COG0589	response to stress
KO64_RS18390	COG2723	6-phospho-beta-galactosidase activity
KO64_RS18395	COG1263	PTS System
KO64_RS18395	COG2190	(PTS) system
KO64_RS18395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KO64_RS18410	COG0494	nUDIX hydrolase
KO64_RS18415	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
KO64_RS18420	COG3507	Belongs to the glycosyl hydrolase 43 family
KO64_RS18445	COG0010	Belongs to the arginase family
KO64_RS18450	COG0833	amino acid
KO64_RS18455	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KO64_RS18460	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KO64_RS18470	COG2390	Transcriptional regulator
KO64_RS18475	COG0561	phosphatase activity
KO64_RS18505	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KO64_RS18510	COG5294	Protein conserved in bacteria
KO64_RS18515	COG0577	efflux transmembrane transporter activity
KO64_RS18520	COG1136	(ABC) transporter
KO64_RS18525	COG2205	protein histidine kinase activity
KO64_RS18530	COG0745	RESPONSE REGULATOR receiver
KO64_RS18545	COG1082	Xylose isomerase domain protein TIM barrel
KO64_RS18555	COG2814	Major facilitator Superfamily
KO64_RS18585	COG1349	DNA-binding transcription factor activity
KO64_RS18590	COG0667	Aldo Keto reductase
KO64_RS18595	COG2814	Major facilitator Superfamily
KO64_RS18610	COG1028	Short-chain dehydrogenase reductase Sdr
KO64_RS18615	COG2197	response regulator
KO64_RS18620	COG4585	Histidine kinase
KO64_RS18625	COG3239	Fatty acid desaturase
KO64_RS18630	COG1309	transcriptional regulator
KO64_RS18635	COG1012	belongs to the aldehyde dehydrogenase family
KO64_RS18640	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KO64_RS18650	COG0640	Transcriptional regulator
KO64_RS18655	COG2814	Major facilitator Superfamily
KO64_RS18660	COG1714	RDD family
KO64_RS18670	COG0450	alkyl hydroperoxide reductase
KO64_RS18675	COG3634	alkyl hydroperoxide reductase activity
KO64_RS18680	COG3177	Filamentation induced by cAMP protein fic
KO64_RS18685	COG1113	amino acid transport
KO64_RS18695	COG2080	2 iron, 2 sulfur cluster binding
KO64_RS18710	COG2068	MobA-Related Protein
KO64_RS18715	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KO64_RS18745	COG0232	Belongs to the dGTPase family. Type 2 subfamily
KO64_RS18765	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
KO64_RS18770	COG0667	Aldo Keto reductase
KO64_RS18775	COG0456	acetyltransferase
KO64_RS18780	COG0457	Tetratricopeptide repeat
KO64_RS18785	COG0010	Belongs to the arginase family
KO64_RS18790	COG0833	amino acid
KO64_RS18795	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KO64_RS18800	COG3829	transcription factor binding
KO64_RS18810	COG0488	(ABC) transporter
KO64_RS18825	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KO64_RS18830	COG5002	protein histidine kinase activity
KO64_RS18830	COG3850	Histidine kinase
KO64_RS18835	COG0745	RESPONSE REGULATOR receiver
KO64_RS18840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KO64_RS18845	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KO64_RS18850	COG4853	Protein conserved in bacteria
KO64_RS18855	COG4863	YycH protein
KO64_RS18860	COG5002	protein histidine kinase activity
KO64_RS18865	COG0745	RESPONSE REGULATOR receiver
KO64_RS18900	COG0346	lactoylglutathione lyase activity
KO64_RS18905	COG0305	Participates in initiation and elongation during chromosome replication
KO64_RS18920	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KO64_RS18935	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KO64_RS18940	COG0438	transferase activity, transferring glycosyl groups
KO64_RS18960	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KO64_RS18965	COG4241	membrane
KO64_RS18975	COG5577	PFAM Coat F domain
KO64_RS18980	COG1733	regulation of RNA biosynthetic process
KO64_RS18995	COG2801	Transposase and inactivated derivatives
KO64_RS19000	COG0697	spore germination
KO64_RS19005	COG1621	beta-fructofuranosidase activity
KO64_RS19010	COG1621	beta-fructofuranosidase activity
KO64_RS19015	COG1802	Transcriptional regulator
KO64_RS19020	COG2318	DinB family
KO64_RS19025	COG2211	Major facilitator Superfamily
KO64_RS19030	COG2197	response regulator
KO64_RS19035	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KO64_RS19035	COG0512	Glutamine amidotransferase of anthranilate synthase
KO64_RS19040	COG0697	spore germination
KO64_RS19050	COG0583	DNA-binding transcription factor activity
KO64_RS19065	COG0778	Nitroreductase
KO64_RS19070	COG1846	Transcriptional regulator
KO64_RS19075	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KO64_RS19080	COG1846	Transcriptional regulator
KO64_RS19085	COG2153	protein acetylation
KO64_RS19095	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KO64_RS19100	COG0583	DNA-binding transcription factor activity
KO64_RS19105	COG1028	Short-chain dehydrogenase reductase Sdr
KO64_RS19110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KO64_RS19115	COG0697	spore germination
KO64_RS19120	COG1331	Highly conserved protein containing a thioredoxin domain
KO64_RS19125	COG1266	CAAX protease self-immunity
KO64_RS19130	COG0477	Major facilitator Superfamily
KO64_RS19130	COG2814	Major facilitator Superfamily
KO64_RS19135	COG0346	lactoylglutathione lyase activity
KO64_RS19140	COG1609	Transcriptional regulator
KO64_RS19145	COG0708	Exodeoxyribonuclease III
KO64_RS19150	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KO64_RS19155	COG2169	Transcriptional regulator
KO64_RS19165	COG0629	single-stranded DNA binding
KO64_RS19175	COG0012	GTP binding
KO64_RS19180	COG0243	molybdopterin cofactor binding
KO64_RS19185	COG4481	Protein conserved in bacteria
KO64_RS19190	COG3949	Membrane
KO64_RS19205	COG1475	DNA binding
KO64_RS19210	COG1192	Involved in chromosome partitioning
KO64_RS19235	COG1847	R3H domain protein
KO64_RS19240	COG0706	membrane insertase activity
KO64_RS19255	COG5444	nuclease activity