locus-tag	class	description
IHV08_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IHV08_RS00010	COG0592	DNA-directed DNA polymerase activity
IHV08_RS00015	COG2501	S4 domain
IHV08_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IHV08_RS00030	COG0187	DNA topoisomerase II activity
IHV08_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IHV08_RS00070	COG0516	GMP reductase activity
IHV08_RS00070	COG0517	IMP dehydrogenase activity
IHV08_RS00075	COG1686	Belongs to the peptidase S11 family
IHV08_RS00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IHV08_RS00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IHV08_RS00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IHV08_RS00100	COG1428	Deoxynucleoside kinase
IHV08_RS00105	COG1428	Deoxynucleoside kinase
IHV08_RS00110	COG3858	chitin binding
IHV08_RS00110	COG1388	LysM domain
IHV08_RS00115	COG1335	isochorismatase
IHV08_RS00120	COG0590	tRNA wobble adenosine to inosine editing
IHV08_RS00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IHV08_RS00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IHV08_RS00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IHV08_RS00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
IHV08_RS00190	COG3853	Toxic anion resistance protein (TelA)
IHV08_RS00195	COG1982	Orn Lys Arg decarboxylase major
IHV08_RS00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IHV08_RS00205	COG3870	Protein conserved in bacteria
IHV08_RS00210	COG1728	Protein conserved in bacteria
IHV08_RS00215	COG0470	DNA polymerase III
IHV08_RS00220	COG1774	PSP1 C-terminal conserved region
IHV08_RS00225	COG4467	Involved in initiation control of chromosome replication
IHV08_RS00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
IHV08_RS00235	COG2827	Endonuclease containing a URI domain
IHV08_RS00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IHV08_RS00245	COG2002	toxin-antitoxin pair type II binding
IHV08_RS00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IHV08_RS00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IHV08_RS00255	COG0084	hydrolase, TatD family'
IHV08_RS00260	COG3583	domain protein
IHV08_RS00260	COG3584	3D domain protein
IHV08_RS00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IHV08_RS00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IHV08_RS00280	COG4466	Protein conserved in bacteria
IHV08_RS00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IHV08_RS00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IHV08_RS00300	COG0251	oxidation-reduction process
IHV08_RS00305	COG2088	sporulation resulting in formation of a cellular spore
IHV08_RS00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IHV08_RS00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IHV08_RS00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IHV08_RS00325	COG0193	aminoacyl-tRNA hydrolase activity
IHV08_RS00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IHV08_RS00340	COG2002	toxin-antitoxin pair type II binding
IHV08_RS00345	COG2244	polysaccharide biosynthetic process
IHV08_RS00350	COG3956	TIGRFAM MazG family protein
IHV08_RS00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IHV08_RS00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IHV08_RS00375	COG1098	S1 RNA binding domain
IHV08_RS00390	COG2208	phosphoserine phosphatase activity
IHV08_RS00395	COG2304	oxidoreductase activity
IHV08_RS00400	COG0515	serine threonine protein kinase
IHV08_RS00405	COG0037	tRNA processing
IHV08_RS00410	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
IHV08_RS00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IHV08_RS00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IHV08_RS00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IHV08_RS00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IHV08_RS00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IHV08_RS00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IHV08_RS00445	COG0512	Glutamine amidotransferase of anthranilate synthase
IHV08_RS00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IHV08_RS00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IHV08_RS00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IHV08_RS00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IHV08_RS00470	COG1396	sequence-specific DNA binding
IHV08_RS00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IHV08_RS00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IHV08_RS00560	COG4463	regulation of RNA biosynthetic process
IHV08_RS00565	COG3880	PFAM UvrB UvrC protein
IHV08_RS00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
IHV08_RS00575	COG0542	response to heat
IHV08_RS00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IHV08_RS00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
IHV08_RS00590	COG4956	integral membrane protein (PIN domain superfamily)
IHV08_RS00595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IHV08_RS00600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
IHV08_RS00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IHV08_RS00610	COG1045	serine acetyltransferase
IHV08_RS00615	COG0215	cysteine-tRNA ligase activity
IHV08_RS00620	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IHV08_RS00625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IHV08_RS00630	COG3688	RNA-binding protein containing a PIN domain
IHV08_RS00635	COG1595	DNA-templated transcription, initiation
IHV08_RS00645	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IHV08_RS00650	COG0250	Participates in transcription elongation, termination and antitermination
IHV08_RS00660	COG0081	regulation of translation
IHV08_RS00665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IHV08_RS00675	COG2813	Specifically methylates the guanine in position
IHV08_RS00680	COG0085	RNA polymerase activity
IHV08_RS00685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IHV08_RS00690	COG1358	cellular component organization or biogenesis
IHV08_RS00695	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IHV08_RS00700	COG0049	tRNA binding
IHV08_RS00705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IHV08_RS00710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IHV08_RS00715	COG0596	Alpha beta hydrolase
IHV08_RS00725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IHV08_RS00730	COG0088	Forms part of the polypeptide exit tunnel
IHV08_RS00740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IHV08_RS00755	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IHV08_RS00760	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IHV08_RS00770	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IHV08_RS00775	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IHV08_RS00785	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IHV08_RS00795	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IHV08_RS00800	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IHV08_RS00805	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IHV08_RS00810	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IHV08_RS00820	COG0200	Binds to the 23S rRNA
IHV08_RS00825	COG0201	protein transport
IHV08_RS00830	COG0563	adenylate kinase activity
IHV08_RS00835	COG0024	Methionine aminopeptidase
IHV08_RS00850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IHV08_RS00855	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IHV08_RS00860	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IHV08_RS00865	COG0202	RNA polymerase activity
IHV08_RS00870	COG0203	ribosomal protein L17
IHV08_RS00875	COG1122	ATPase activity
IHV08_RS00880	COG1122	ATPase activity
IHV08_RS00885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IHV08_RS00890	COG0101	tRNA pseudouridine synthase activity
IHV08_RS00895	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IHV08_RS00900	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IHV08_RS00905	COG2226	methyltransferase
IHV08_RS00915	COG0860	N-Acetylmuramoyl-L-alanine amidase
IHV08_RS00920	COG0489	protein tyrosine kinase activity
IHV08_RS00930	COG2194	sulfuric ester hydrolase activity
IHV08_RS00935	COG0726	polysaccharide deacetylase
IHV08_RS01025	COG0659	secondary active sulfate transmembrane transporter activity
IHV08_RS01030	COG0385	Bile acid
IHV08_RS01035	COG2819	hydrolase of the alpha beta superfamily
IHV08_RS01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IHV08_RS01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IHV08_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IHV08_RS01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IHV08_RS01055	COG2207	Transcriptional regulator
IHV08_RS01060	COG3876	Protein conserved in bacteria
IHV08_RS01065	COG1472	Belongs to the glycosyl hydrolase 3 family
IHV08_RS01070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IHV08_RS01075	COG1263	PTS System
IHV08_RS01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IHV08_RS01080	COG1737	Transcriptional regulator
IHV08_RS01085	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IHV08_RS01090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IHV08_RS01095	COG1683	Conserved Protein
IHV08_RS01125	COG1595	DNA-templated transcription, initiation
IHV08_RS01130	COG5662	AntiSigma factor
IHV08_RS01135	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IHV08_RS01140	COG4856	YbbR-like protein
IHV08_RS01145	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IHV08_RS01150	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IHV08_RS01160	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IHV08_RS01165	COG2169	Transcriptional regulator
IHV08_RS01170	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IHV08_RS01175	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IHV08_RS01180	COG3002	Belongs to the UPF0753 family
IHV08_RS01185	COG0288	reversible hydration of carbon dioxide
IHV08_RS01195	COG5609	conserved protein (DUF2294)
IHV08_RS01200	COG0640	Transcriptional regulator
IHV08_RS01205	COG2814	Major facilitator Superfamily
IHV08_RS01220	COG0596	Alpha beta hydrolase
IHV08_RS01225	COG0745	RESPONSE REGULATOR receiver
IHV08_RS01230	COG0642	Histidine kinase
IHV08_RS01240	COG0515	serine threonine protein kinase
IHV08_RS01255	COG1113	amino acid transport
IHV08_RS01270	COG2602	Beta-lactamase
IHV08_RS01275	COG2124	cytochrome p450
IHV08_RS01285	COG0531	amino acid
IHV08_RS01290	COG0584	glycerophosphoryl diester phosphodiesterase
IHV08_RS01295	COG2271	Major facilitator Superfamily
IHV08_RS01305	COG1846	Transcriptional regulator
IHV08_RS01305	COG0456	acetyltransferase
IHV08_RS01310	COG2271	Major facilitator Superfamily
IHV08_RS01315	COG0697	spore germination
IHV08_RS01320	COG2207	Transcriptional regulator
IHV08_RS01320	COG1917	Cupin 2, conserved barrel domain protein
IHV08_RS01325	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IHV08_RS01330	COG3591	Belongs to the peptidase S1B family
IHV08_RS01340	COG0596	Alpha beta hydrolase
IHV08_RS01345	COG1183	phosphatidylcholine synthase activity
IHV08_RS01350	COG0586	Pfam SNARE associated Golgi protein
IHV08_RS01355	COG0688	phosphatidylethanolamine metabolic process
IHV08_RS01365	COG2312	Erythromycin esterase
IHV08_RS01370	COG2207	Transcriptional regulator
IHV08_RS01375	COG1054	Belongs to the UPF0176 family
IHV08_RS01380	COG1301	dicarboxylic acid transport
IHV08_RS01385	COG2190	(PTS) system
IHV08_RS01385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IHV08_RS01385	COG1263	PTS System
IHV08_RS01390	COG0363	glucosamine-6-phosphate deaminase activity
IHV08_RS01395	COG2188	Transcriptional regulator
IHV08_RS01405	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IHV08_RS01410	COG0833	amino acid
IHV08_RS01415	COG2040	homocysteine
IHV08_RS01420	COG1115	amino acid carrier protein
IHV08_RS01425	COG2066	Belongs to the glutaminase family
IHV08_RS01430	COG4191	Histidine kinase
IHV08_RS01435	COG0784	Response regulator, receiver
IHV08_RS01440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IHV08_RS01445	COG1012	belongs to the aldehyde dehydrogenase family
IHV08_RS01450	COG2271	Major facilitator Superfamily
IHV08_RS01455	COG4948	Mandelate Racemase Muconate Lactonizing
IHV08_RS01460	COG2186	Transcriptional regulator
IHV08_RS01465	COG2721	sulfolactate sulfo-lyase activity
IHV08_RS01470	COG3173	Aminoglycoside phosphotransferase
IHV08_RS01480	COG0697	spore germination
IHV08_RS01485	COG0745	RESPONSE REGULATOR receiver
IHV08_RS01490	COG2205	protein histidine kinase activity
IHV08_RS01495	COG1131	(ABC) transporter
IHV08_RS01515	COG3773	Cell wall hydrolase
IHV08_RS01520	COG2304	oxidoreductase activity
IHV08_RS01530	COG3540	Alkaline phosphatase
IHV08_RS01535	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IHV08_RS01540	COG0805	protein transport
IHV08_RS01545	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IHV08_RS01550	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IHV08_RS01555	COG0477	Major facilitator Superfamily
IHV08_RS01560	COG1309	transcriptional regulator
IHV08_RS01565	COG0252	asparaginase activity
IHV08_RS01570	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
IHV08_RS01575	COG1714	RDD family
IHV08_RS01580	COG1405	negative regulation of cell septum assembly
IHV08_RS01580	COG3012	SEC-C Motif Domain Protein
IHV08_RS01585	COG3290	protein histidine kinase activity
IHV08_RS01590	COG3279	Response regulator of the LytR AlgR family
IHV08_RS01595	COG4555	ABC transporter
IHV08_RS01600	COG1668	transmembrane transport
IHV08_RS01605	COG0667	Aldo Keto reductase
IHV08_RS01620	COG1595	DNA-templated transcription, initiation
IHV08_RS01625	COG1595	DNA-templated transcription, initiation
IHV08_RS01630	COG1876	peptidase activity
IHV08_RS01635	COG0457	Tetratricopeptide repeat
IHV08_RS01640	COG1028	Short-chain dehydrogenase reductase Sdr
IHV08_RS01645	COG0366	Alpha amylase catalytic
IHV08_RS01650	COG0803	Belongs to the bacterial solute-binding protein 9 family
IHV08_RS01655	COG1121	(ABC) transporter
IHV08_RS01660	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IHV08_RS01665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IHV08_RS01670	COG2310	stress, protein
IHV08_RS01675	COG2310	stress, protein
IHV08_RS01680	COG2310	stress, protein
IHV08_RS01685	COG0861	Integral membrane protein TerC family
IHV08_RS01695	COG3853	Toxic anion resistance protein (TelA)
IHV08_RS01700	COG0477	Major facilitator Superfamily
IHV08_RS01705	COG2814	Major facilitator Superfamily
IHV08_RS01710	COG0640	Transcriptional regulator
IHV08_RS01715	COG4175	Glycine betaine
IHV08_RS01715	COG0517	IMP dehydrogenase activity
IHV08_RS01720	COG4176	ABC-type proline glycine betaine transport system permease component
IHV08_RS01725	COG2113	Glycine betaine
IHV08_RS01730	COG1473	amidohydrolase
IHV08_RS01735	COG1288	antiporter activity
IHV08_RS01745	COG0366	Alpha amylase catalytic
IHV08_RS01750	COG0039	L-malate dehydrogenase activity
IHV08_RS01760	COG2814	Major facilitator Superfamily
IHV08_RS01765	COG1846	Transcriptional regulator
IHV08_RS01770	COG1280	lysine exporter protein (LysE YggA)
IHV08_RS01775	COG3403	YqcI/YcgG family
IHV08_RS01780	COG1113	amino acid transport
IHV08_RS01785	COG3665	Urea carboxylase-associated protein
IHV08_RS01790	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IHV08_RS01795	COG1660	Displays ATPase and GTPase activities
IHV08_RS01800	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IHV08_RS01805	COG2226	methyltransferase
IHV08_RS01810	COG0583	DNA-binding transcription factor activity
IHV08_RS01815	COG3458	cephalosporin-C deacetylase activity
IHV08_RS01820	COG3541	Predicted nucleotidyltransferase
IHV08_RS01825	COG0506	proline dehydrogenase activity
IHV08_RS01830	COG1012	belongs to the aldehyde dehydrogenase family
IHV08_RS01835	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IHV08_RS01840	COG2508	Transcriptional regulator
IHV08_RS01845	COG3689	TIGRFAM TIGR03943 family protein
IHV08_RS01850	COG0701	Predicted permease
IHV08_RS01855	COG2267	carboxylic ester hydrolase activity
IHV08_RS01860	COG0492	ferredoxin-NADP+ reductase activity
IHV08_RS01865	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IHV08_RS01865	COG1587	Uroporphyrinogen-III synthase
IHV08_RS01870	COG2146	nitrite reductase [NAD(P)H] activity
IHV08_RS01875	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IHV08_RS01880	COG0243	molybdopterin cofactor binding
IHV08_RS01885	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IHV08_RS01890	COG2223	nitrite transmembrane transporter activity
IHV08_RS01895	COG1469	GTP cyclohydrolase I activity
IHV08_RS01900	COG1376	ErfK ybiS ycfS ynhG family protein
IHV08_RS01910	COG0523	cobalamin synthesis protein
IHV08_RS01915	COG0765	amino acid transport
IHV08_RS01920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IHV08_RS01940	COG1846	Transcriptional regulator
IHV08_RS01955	COG2723	6-phospho-beta-galactosidase activity
IHV08_RS01965	COG3209	COG3209 Rhs family protein
IHV08_RS01970	COG3290	protein histidine kinase activity
IHV08_RS01970	COG0840	transmembrane signaling receptor activity
IHV08_RS01975	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IHV08_RS01980	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
IHV08_RS01985	COG1733	regulation of RNA biosynthetic process
IHV08_RS01990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IHV08_RS01995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IHV08_RS02000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IHV08_RS02005	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
IHV08_RS02010	COG2814	Major facilitator Superfamily
IHV08_RS02020	COG0697	spore germination
IHV08_RS02035	COG2364	Membrane
IHV08_RS02040	COG1126	abc transporter atp-binding protein
IHV08_RS02045	COG0765	amino acid transport
IHV08_RS02050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IHV08_RS02055	COG0583	DNA-binding transcription factor activity
IHV08_RS02060	COG0163	prenyltransferase activity
IHV08_RS02065	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IHV08_RS02080	COG0596	Alpha beta hydrolase
IHV08_RS02085	COG3104	oligopeptide transport
IHV08_RS02090	COG5434	Belongs to the glycosyl hydrolase 28 family
IHV08_RS02100	COG0697	spore germination
IHV08_RS02110	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IHV08_RS02115	COG1136	(ABC) transporter
IHV08_RS02120	COG0577	efflux transmembrane transporter activity
IHV08_RS02125	COG0745	RESPONSE REGULATOR receiver
IHV08_RS02130	COG5002	protein histidine kinase activity
IHV08_RS02130	COG3850	Histidine kinase
IHV08_RS02135	COG0457	Tetratricopeptide repeat
IHV08_RS02155	COG0527	aspartate kinase activity
IHV08_RS02160	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IHV08_RS02165	COG4605	iron ion homeostasis
IHV08_RS02170	COG4604	ABC transporter, ATP-binding protein
IHV08_RS02175	COG4607	ABC-type enterochelin transport system periplasmic component
IHV08_RS02180	COG2814	Major facilitator Superfamily
IHV08_RS02185	COG1309	transcriptional regulator
IHV08_RS02190	COG0778	Nitroreductase
IHV08_RS02195	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IHV08_RS02200	COG0640	Transcriptional regulator
IHV08_RS02205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IHV08_RS02210	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IHV08_RS02215	COG1012	belongs to the aldehyde dehydrogenase family
IHV08_RS02220	COG4975	Glucose uptake
IHV08_RS02225	COG1028	Short-chain dehydrogenase reductase Sdr
IHV08_RS02230	COG4549	nuclear export factor GLE1
IHV08_RS02235	COG1276	copper resistance
IHV08_RS02235	COG2372	response to copper ion
IHV08_RS02240	COG1349	DNA-binding transcription factor activity
IHV08_RS02250	COG2213	PTS system mannitol-specific
IHV08_RS02255	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IHV08_RS02260	COG0246	Mannitol dehydrogenase
IHV08_RS02265	COG0473	3-isopropylmalate dehydrogenase activity
IHV08_RS02270	COG0681	Belongs to the peptidase S26 family
IHV08_RS02275	COG0412	Dienelactone hydrolase
IHV08_RS02280	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IHV08_RS02290	COG0561	phosphatase activity
IHV08_RS02295	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
IHV08_RS02300	COG1914	H( )-stimulated, divalent metal cation uptake system
IHV08_RS02305	COG4336	lyase activity
IHV08_RS02310	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
IHV08_RS02315	COG1984	allophanate hydrolase subunit 2
IHV08_RS02320	COG1414	Transcriptional regulator
IHV08_RS02325	COG2755	lipolytic protein G-D-S-L family
IHV08_RS02335	COG2329	Antibiotic biosynthesis monooxygenase
IHV08_RS02340	COG0768	penicillin binding
IHV08_RS02345	COG4989	oxidoreductase activity
IHV08_RS02350	COG3711	transcriptional antiterminator
IHV08_RS02355	COG0318	PFAM AMP-dependent synthetase and ligase
IHV08_RS02360	COG2226	methyltransferase
IHV08_RS02365	COG1028	Short-chain dehydrogenase reductase Sdr
IHV08_RS02370	COG1917	Cupin 2, conserved barrel domain protein
IHV08_RS02375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IHV08_RS02380	COG3871	stress protein (general stress protein 26)
IHV08_RS02390	COG2814	Major facilitator Superfamily
IHV08_RS02395	COG1522	sequence-specific DNA binding
IHV08_RS02400	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IHV08_RS02400	COG0551	DNA topoisomerase type I activity
IHV08_RS02405	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
IHV08_RS02410	COG3706	GGDEF domain
IHV08_RS02415	COG5298	Protein conserved in bacteria
IHV08_RS02420	COG1215	transferase activity, transferring glycosyl groups
IHV08_RS02430	COG0531	amino acid
IHV08_RS02435	COG0494	nUDIX hydrolase
IHV08_RS02440	COG0028	Belongs to the TPP enzyme family
IHV08_RS02455	COG1914	H( )-stimulated, divalent metal cation uptake system
IHV08_RS02460	COG2261	transglycosylase associated protein
IHV08_RS02465	COG4876	unkown
IHV08_RS02470	COG2217	Heavy metal translocating P-type atpase
IHV08_RS02475	COG3729	General stress protein
IHV08_RS02480	COG0662	Cupin 2, conserved barrel domain protein
IHV08_RS02485	COG2329	Antibiotic biosynthesis monooxygenase
IHV08_RS02490	COG3546	catalase activity
IHV08_RS02495	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IHV08_RS02500	COG3290	protein histidine kinase activity
IHV08_RS02505	COG4565	transcriptional regulatory protein
IHV08_RS02510	COG1301	dicarboxylic acid transport
IHV08_RS02515	COG0628	permease
IHV08_RS02520	COG1131	(ABC) transporter
IHV08_RS02525	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
IHV08_RS02535	COG1960	acyl-CoA dehydrogenase activity
IHV08_RS02550	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IHV08_RS02555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IHV08_RS02560	COG1181	Belongs to the D-alanine--D-alanine ligase family
IHV08_RS02565	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IHV08_RS02570	COG0513	Belongs to the DEAD box helicase family
IHV08_RS02575	COG3402	PFAM membrane-flanked domain
IHV08_RS02580	COG3428	Bacterial PH domain
IHV08_RS02585	COG0705	Rhomboid family
IHV08_RS02590	COG0736	holo-[acyl-carrier-protein] synthase activity
IHV08_RS02595	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IHV08_RS02600	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IHV08_RS02605	COG0864	Transcriptional regulator
IHV08_RS02610	COG2337	Toxic component of a toxin-antitoxin (TA) module
IHV08_RS02615	COG1366	Belongs to the anti-sigma-factor antagonist family
IHV08_RS02620	COG1366	Belongs to the anti-sigma-factor antagonist family
IHV08_RS02625	COG2172	sigma factor antagonist activity
IHV08_RS02630	COG2208	phosphoserine phosphatase activity
IHV08_RS02635	COG1366	Belongs to the anti-sigma-factor antagonist family
IHV08_RS02640	COG2172	sigma factor antagonist activity
IHV08_RS02645	COG1191	sigma factor activity
IHV08_RS02650	COG2208	phosphoserine phosphatase activity
IHV08_RS02665	COG1673	EVE domain
IHV08_RS02670	COG1846	Transcriptional regulator
IHV08_RS02675	COG2183	response to ionizing radiation
IHV08_RS02685	COG3091	SprT-like family
IHV08_RS02725	COG1476	TRANSCRIPTIONal
IHV08_RS02730	COG3239	Fatty acid desaturase
IHV08_RS02740	COG1278	Cold shock
IHV08_RS02745	COG1329	Transcriptional regulator
IHV08_RS02750	COG0697	spore germination
IHV08_RS02755	COG2207	Transcriptional regulator
IHV08_RS02755	COG1917	Cupin 2, conserved barrel domain protein
IHV08_RS02760	COG0697	spore germination
IHV08_RS02765	COG2207	Transcriptional regulator
IHV08_RS02765	COG3708	Transcriptional regulator
IHV08_RS02770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IHV08_RS02775	COG0477	Major facilitator Superfamily
IHV08_RS02785	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
IHV08_RS02795	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IHV08_RS02800	COG1309	transcriptional regulator
IHV08_RS02805	COG0697	spore germination
IHV08_RS02810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IHV08_RS02815	COG2030	dehydratase
IHV08_RS02820	COG3545	Serine hydrolase
IHV08_RS02825	COG1733	regulation of RNA biosynthetic process
IHV08_RS02830	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IHV08_RS02835	COG1733	regulation of RNA biosynthetic process
IHV08_RS02840	COG2249	NAD(P)H dehydrogenase (quinone) activity
IHV08_RS02845	COG2814	Major facilitator Superfamily
IHV08_RS02850	COG1309	transcriptional regulator
IHV08_RS02855	COG0640	Transcriptional regulator
IHV08_RS02860	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IHV08_RS02870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IHV08_RS02875	COG0697	spore germination
IHV08_RS02880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IHV08_RS02885	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IHV08_RS02890	COG0640	Transcriptional regulator
IHV08_RS02895	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IHV08_RS02910	COG4585	Histidine kinase
IHV08_RS02915	COG2197	response regulator
IHV08_RS02920	COG2409	Drug exporters of the RND superfamily
IHV08_RS02925	COG0596	Alpha beta hydrolase
IHV08_RS02930	COG1811	Na channel or pump
IHV08_RS02935	COG4978	Transcriptional regulator
IHV08_RS02935	COG0789	Transcriptional regulator
IHV08_RS02940	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IHV08_RS02945	COG0778	Nitroreductase
IHV08_RS02950	COG0346	lactoylglutathione lyase activity
IHV08_RS02955	COG2259	Doxx family
IHV08_RS02960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IHV08_RS02975	COG2323	membrane
IHV08_RS02980	COG2323	membrane
IHV08_RS02985	COG0071	Belongs to the small heat shock protein (HSP20) family
IHV08_RS03000	COG1309	transcriptional regulator
IHV08_RS03010	COG0456	acetyltransferase
IHV08_RS03015	COG0488	(ABC) transporter
IHV08_RS03020	COG1113	amino acid transport
IHV08_RS03025	COG2318	DinB family
IHV08_RS03030	COG1846	Transcriptional regulator
IHV08_RS03035	COG2409	Drug exporters of the RND superfamily
IHV08_RS03035	COG1033	growth of symbiont in host cell
IHV08_RS03040	COG0778	Nitroreductase
IHV08_RS03045	COG1846	Transcriptional regulator
IHV08_RS03050	COG2814	Major facilitator Superfamily
IHV08_RS03055	COG0730	response to heat
IHV08_RS03060	COG1802	Transcriptional regulator
IHV08_RS03065	COG3858	chitin binding
IHV08_RS03065	COG1388	LysM domain
IHV08_RS03070	COG1819	glycosyl
IHV08_RS03080	COG1785	Belongs to the alkaline phosphatase family
IHV08_RS03085	COG5646	InterPro IPR014922
IHV08_RS03095	COG0454	-acetyltransferase
IHV08_RS03100	COG1078	dGTPase activity
IHV08_RS03105	COG1388	LysM domain
IHV08_RS03110	COG2814	Major facilitator Superfamily
IHV08_RS03115	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IHV08_RS03120	COG1447	Phosphotransferase system cellobiose-specific component IIA
IHV08_RS03125	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IHV08_RS03130	COG2723	6-phospho-beta-galactosidase activity
IHV08_RS03135	COG2188	Transcriptional regulator
IHV08_RS03140	COG1940	carbohydrate kinase activity
IHV08_RS03145	COG1482	cell wall glycoprotein biosynthetic process
IHV08_RS03150	COG4124	Belongs to the glycosyl hydrolase 26 family
IHV08_RS03195	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IHV08_RS03200	COG0802	atpase or kinase
IHV08_RS03205	COG1214	PFAM Peptidase M22, glycoprotease
IHV08_RS03210	COG0456	acetyltransferase
IHV08_RS03215	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IHV08_RS03220	COG0488	(ABC) transporter
IHV08_RS03225	COG0315	cyclic pyranopterin monophosphate synthase activity
IHV08_RS03230	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IHV08_RS03235	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IHV08_RS03240	COG0805	protein transport
IHV08_RS03250	COG1266	CAAX protease self-immunity
IHV08_RS03260	COG0459	protein refolding
IHV08_RS03265	COG4974	Belongs to the 'phage' integrase family
IHV08_RS03270	COG2856	Zn peptidase
IHV08_RS03285	COG1396	sequence-specific DNA binding
IHV08_RS03330	COG5377	YqaJ viral recombinase family
IHV08_RS03335	COG3723	Recombinational DNA repair protein, rece pathway
IHV08_RS03340	COG3935	DnaD domain protein
IHV08_RS03345	COG1484	DNA-dependent DNA replication
IHV08_RS03355	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
IHV08_RS03420	COG3677	Transposase
IHV08_RS03440	COG5484	DNA packaging
IHV08_RS03445	COG1783	phage Terminase large subunit
IHV08_RS03565	COG5632	N-Acetylmuramoyl-L-alanine amidase
IHV08_RS03565	COG1388	LysM domain
IHV08_RS03565	COG3409	Peptidoglycan-binding domain 1 protein
IHV08_RS03595	COG3409	Peptidoglycan-binding domain 1 protein
IHV08_RS03605	COG0457	Tetratricopeptide repeat
IHV08_RS03610	COG1063	alcohol dehydrogenase
IHV08_RS03615	COG2211	Major facilitator Superfamily
IHV08_RS03620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IHV08_RS03625	COG1842	Phage shock protein A
IHV08_RS03630	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IHV08_RS03635	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IHV08_RS03640	COG4260	virion core protein, lumpy skin disease virus
IHV08_RS03650	COG2814	Major facilitator Superfamily
IHV08_RS03655	COG1063	alcohol dehydrogenase
IHV08_RS03660	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IHV08_RS03665	COG0823	Involved in the tonB-independent uptake of proteins
IHV08_RS03680	COG2267	carboxylic ester hydrolase activity
IHV08_RS03690	COG2132	Multicopper oxidase
IHV08_RS03695	COG1113	amino acid transport
IHV08_RS03705	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IHV08_RS03710	COG0714	Associated with various cellular activities
IHV08_RS03715	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
IHV08_RS03720	COG1305	Transglutaminase-like
IHV08_RS03725	COG0519	Catalyzes the synthesis of GMP from XMP
IHV08_RS03725	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IHV08_RS03740	COG2252	PERMEase
IHV08_RS03745	COG3064	Membrane
IHV08_RS03755	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
IHV08_RS03765	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IHV08_RS03770	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IHV08_RS03775	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IHV08_RS03780	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IHV08_RS03785	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IHV08_RS03790	COG0047	phosphoribosylformylglycinamidine synthase activity
IHV08_RS03795	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IHV08_RS03800	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IHV08_RS03805	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IHV08_RS03810	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IHV08_RS03815	COG0138	bifunctional purine biosynthesis protein purh
IHV08_RS03820	COG0151	Belongs to the GarS family
IHV08_RS03825	COG1522	sequence-specific DNA binding
IHV08_RS03830	COG0531	amino acid
IHV08_RS03840	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IHV08_RS03845	COG1470	cell adhesion involved in biofilm formation
IHV08_RS03850	COG4496	protein, YerC YecD
IHV08_RS03855	COG0069	glutamate synthase activity
IHV08_RS03860	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
IHV08_RS03865	COG0210	DNA helicase
IHV08_RS03870	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IHV08_RS03875	COG4851	CamS sex pheromone cAM373 precursor
IHV08_RS03880	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IHV08_RS03885	COG1285	pathogenesis
IHV08_RS03890	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IHV08_RS03895	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IHV08_RS03900	COG0154	amidase activity
IHV08_RS03905	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IHV08_RS03910	COG1309	transcriptional regulator
IHV08_RS03915	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IHV08_RS03920	COG1597	lipid kinase activity
IHV08_RS03925	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IHV08_RS03940	COG5444	nuclease activity
IHV08_RS03945	COG3391	amine dehydrogenase activity
IHV08_RS03960	COG0457	Tetratricopeptide repeat
IHV08_RS03970	COG0217	transcriptional regulatory protein
IHV08_RS03980	COG1309	transcriptional regulator
IHV08_RS03985	COG3631	Ketosteroid isomerase-related protein
IHV08_RS03990	COG0702	epimerase
IHV08_RS04005	COG3546	catalase activity
IHV08_RS04010	COG0454	-acetyltransferase
IHV08_RS04020	COG5578	integral membrane protein
IHV08_RS04025	COG2972	Histidine kinase
IHV08_RS04030	COG2207	Transcriptional regulator
IHV08_RS04030	COG4753	response regulator
IHV08_RS04035	COG1653	transport
IHV08_RS04040	COG1175	transmembrane transport
IHV08_RS04045	COG0395	ABC-type sugar transport system, permease component
IHV08_RS04050	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
IHV08_RS04055	COG2207	Transcriptional regulator
IHV08_RS04060	COG2755	lipolytic protein G-D-S-L family
IHV08_RS04070	COG5578	integral membrane protein
IHV08_RS04075	COG3401	FG-GAP repeat protein
IHV08_RS04080	COG3401	FG-GAP repeat protein
IHV08_RS04085	COG2755	lipolytic protein G-D-S-L family
IHV08_RS04090	COG1874	Beta-galactosidase
IHV08_RS04100	COG1653	transport
IHV08_RS04105	COG4209	transmembrane transport
IHV08_RS04110	COG0395	ABC-type sugar transport system, permease component
IHV08_RS04115	COG1486	melibiose metabolic process
IHV08_RS04120	COG2323	membrane
IHV08_RS04125	COG2329	Antibiotic biosynthesis monooxygenase
IHV08_RS04130	COG0346	lactoylglutathione lyase activity
IHV08_RS04145	COG5583	Uncharacterized small protein (DUF2292)
IHV08_RS04150	COG0670	Belongs to the BI1 family
IHV08_RS04155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IHV08_RS04170	COG2124	cytochrome p450
IHV08_RS04170	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IHV08_RS04175	COG1368	sulfuric ester hydrolase activity
IHV08_RS04180	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IHV08_RS04185	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IHV08_RS04190	COG1442	glycosyl transferase family 8
IHV08_RS04195	COG1216	Glycosyl transferase, family 2
IHV08_RS04200	COG1442	glycosyl transferase family 8
IHV08_RS04205	COG2223	nitrite transmembrane transporter activity
IHV08_RS04210	COG1011	Hydrolase
IHV08_RS04215	COG0531	amino acid
IHV08_RS04220	COG1012	belongs to the aldehyde dehydrogenase family
IHV08_RS04225	COG0840	transmembrane signaling receptor activity
IHV08_RS04230	COG0488	(ABC) transporter
IHV08_RS04240	COG0789	Transcriptional regulator
IHV08_RS04245	COG2814	Major facilitator Superfamily
IHV08_RS04255	COG0488	(ABC) transporter
IHV08_RS04260	COG0513	Belongs to the DEAD box helicase family
IHV08_RS04265	COG0456	acetyltransferase
IHV08_RS04270	COG2130	NADP-dependent
IHV08_RS04275	COG2211	Major facilitator Superfamily
IHV08_RS04280	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IHV08_RS04285	COG1120	ATPase activity
IHV08_RS04290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IHV08_RS04295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IHV08_RS04300	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
IHV08_RS04315	COG3866	Pectate lyase
IHV08_RS04320	COG0471	metal ion transport
IHV08_RS04325	COG3290	protein histidine kinase activity
IHV08_RS04330	COG4565	transcriptional regulatory protein
IHV08_RS04335	COG3181	Tripartite tricarboxylate transporter family receptor
IHV08_RS04340	COG2851	Citrate transporter
IHV08_RS04345	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IHV08_RS04350	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
IHV08_RS04355	COG1254	Belongs to the acylphosphatase family
IHV08_RS04360	COG2258	MOSC domain
IHV08_RS04380	COG0024	Methionine aminopeptidase
IHV08_RS04385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IHV08_RS04385	COG1263	PTS System
IHV08_RS04390	COG1368	sulfuric ester hydrolase activity
IHV08_RS04405	COG1115	amino acid carrier protein
IHV08_RS04410	COG0531	amino acid
IHV08_RS04425	COG0697	spore germination
IHV08_RS04430	COG1263	PTS System
IHV08_RS04430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IHV08_RS04435	COG0366	Alpha amylase catalytic
IHV08_RS04440	COG2188	Transcriptional regulator
IHV08_RS04445	COG0778	Nitroreductase
IHV08_RS04450	COG0737	Belongs to the 5'-nucleotidase family
IHV08_RS04455	COG0693	protein deglycase activity
IHV08_RS04460	COG2814	Major facilitator Superfamily
IHV08_RS04465	COG4840	Belongs to the UPF0435 family
IHV08_RS04470	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IHV08_RS04475	COG4980	gas vesicle protein
IHV08_RS04480	COG1295	ribonuclease BN
IHV08_RS04485	COG0477	Major facilitator Superfamily
IHV08_RS04490	COG0387	Pfam Sodium calcium exchanger
IHV08_RS04500	COG0668	transmembrane transport
IHV08_RS04505	COG0535	radical SAM domain protein
IHV08_RS04515	COG0726	polysaccharide deacetylase
IHV08_RS04520	COG2084	Dehydrogenase
IHV08_RS04525	COG0598	Magnesium transport protein CorA
IHV08_RS04530	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IHV08_RS04535	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IHV08_RS04545	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IHV08_RS04550	COG4637	Psort location Cytoplasmic, score
IHV08_RS04560	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IHV08_RS04565	COG0022	dehydrogenase e1 component
IHV08_RS04570	COG0508	dehydrogenase complex catalyzes the overall conversion of
IHV08_RS04575	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IHV08_RS04580	COG3284	Transcriptional regulator
IHV08_RS04590	COG1742	UPF0060 membrane protein
IHV08_RS04610	COG4842	Belongs to the WXG100 family
IHV08_RS04615	COG1486	melibiose metabolic process
IHV08_RS04620	COG1737	Transcriptional regulator
IHV08_RS04625	COG1263	PTS System
IHV08_RS04625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IHV08_RS04630	COG5434	Belongs to the glycosyl hydrolase 28 family
IHV08_RS04635	COG1132	(ABC) transporter
IHV08_RS04640	COG1132	(ABC) transporter
IHV08_RS04645	COG2259	Doxx family
IHV08_RS04650	COG2514	catechol 2,3-dioxygenase activity
IHV08_RS04655	COG4585	Histidine kinase
IHV08_RS04660	COG2197	response regulator
IHV08_RS04665	COG1131	(ABC) transporter
IHV08_RS04670	COG0842	Transport permease protein
IHV08_RS04670	COG1511	domain protein
IHV08_RS04675	COG0842	Transport permease protein
IHV08_RS04680	COG1695	Transcriptional regulator
IHV08_RS04685	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
IHV08_RS04690	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
IHV08_RS04695	COG2318	DinB family
IHV08_RS04700	COG2814	Major facilitator Superfamily
IHV08_RS04705	COG1846	Transcriptional regulator
IHV08_RS04710	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IHV08_RS04710	COG0392	lysyltransferase activity
IHV08_RS04715	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IHV08_RS04720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IHV08_RS04725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IHV08_RS04730	COG0384	phenazine biosynthesis protein PhzF
IHV08_RS04735	COG0778	Nitroreductase
IHV08_RS04750	COG1090	epimerase
IHV08_RS04755	COG2137	regulation of response to DNA damage stimulus
IHV08_RS04765	COG2814	Major facilitator Superfamily
IHV08_RS04780	COG3103	Sh3 type 3 domain protein
IHV08_RS04785	COG5658	integral membrane protein
IHV08_RS04790	COG0596	Alpha beta hydrolase
IHV08_RS04795	COG0463	Glycosyl transferase, family 2
IHV08_RS04800	COG4485	Bacterial membrane protein, YfhO
IHV08_RS04805	COG1988	membrane-bound metal-dependent
IHV08_RS04810	COG1194	a g-specific adenine glycosylase
IHV08_RS04820	COG1028	Short-chain dehydrogenase reductase Sdr
IHV08_RS04835	COG3557	Belongs to the UPF0374 family
IHV08_RS04840	COG1132	(ABC) transporter
IHV08_RS04845	COG4129	membrane
IHV08_RS04850	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IHV08_RS04855	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IHV08_RS04860	COG0735	belongs to the Fur family
IHV08_RS04970	COG4326	sporulation control protein
IHV08_RS04980	COG5577	PFAM Coat F domain
IHV08_RS04985	COG3340	Belongs to the peptidase S51 family
IHV08_RS04990	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IHV08_RS04995	COG0277	FAD linked oxidase domain protein
IHV08_RS05005	COG0753	catalase activity
IHV08_RS05010	COG1116	anion transmembrane transporter activity
IHV08_RS05015	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IHV08_RS05020	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IHV08_RS05025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IHV08_RS05035	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IHV08_RS05045	COG1476	TRANSCRIPTIONal
IHV08_RS05055	COG3382	B3 4 domain protein
IHV08_RS05060	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IHV08_RS05070	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IHV08_RS05075	COG0789	Transcriptional regulator
IHV08_RS05080	COG1664	Polymer-forming cytoskeletal
IHV08_RS05085	COG1664	Polymer-forming cytoskeletal
IHV08_RS05090	COG2766	serine protein kinase
IHV08_RS05095	COG2718	Belongs to the UPF0229 family
IHV08_RS05100	COG1846	Transcriptional regulator
IHV08_RS05105	COG1566	PFAM secretion protein HlyD family protein
IHV08_RS05110	COG2814	Major facilitator Superfamily
IHV08_RS05115	COG0655	NAD(P)H dehydrogenase (quinone) activity
IHV08_RS05135	COG1725	Transcriptional regulator
IHV08_RS05140	COG1131	(ABC) transporter
IHV08_RS05145	COG1131	(ABC) transporter
IHV08_RS05150	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
IHV08_RS05155	COG1278	Cold shock
IHV08_RS05160	COG1464	Belongs to the NlpA lipoprotein family
IHV08_RS05165	COG3706	GGDEF domain
IHV08_RS05170	COG1823	symporter activity
IHV08_RS05190	COG5577	PFAM Coat F domain
IHV08_RS05200	COG3764	Sortase (surface protein transpeptidase)
IHV08_RS05205	COG0564	pseudouridine synthase activity
IHV08_RS05215	COG0517	IMP dehydrogenase activity
IHV08_RS05220	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IHV08_RS05225	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IHV08_RS05225	COG3153	acetyltransferase
IHV08_RS05230	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IHV08_RS05235	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
IHV08_RS05240	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IHV08_RS05245	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IHV08_RS05250	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IHV08_RS05255	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IHV08_RS05260	COG2203	Gaf domain
IHV08_RS05260	COG4585	Histidine kinase
IHV08_RS05265	COG2197	response regulator
IHV08_RS05270	COG0431	NADPH-dependent FMN reductase
IHV08_RS05285	COG0791	NLP P60 protein
IHV08_RS05285	COG1388	LysM domain
IHV08_RS05290	COG1959	2 iron, 2 sulfur cluster binding
IHV08_RS05295	COG0668	transmembrane transport
IHV08_RS05300	COG2719	SpoVR family
IHV08_RS05305	COG1785	Belongs to the alkaline phosphatase family
IHV08_RS05310	COG0791	NLP P60 protein
IHV08_RS05310	COG1388	LysM domain
IHV08_RS05315	COG0583	DNA-binding transcription factor activity
IHV08_RS05320	COG0372	Belongs to the citrate synthase family
IHV08_RS05325	COG1028	Short-chain dehydrogenase reductase Sdr
IHV08_RS05330	COG0531	amino acid
IHV08_RS05335	COG0733	neurotransmitter:sodium symporter activity
IHV08_RS05340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IHV08_RS05345	COG0456	acetyltransferase
IHV08_RS05360	COG1595	DNA-templated transcription, initiation
IHV08_RS05365	COG0667	Aldo Keto reductase
IHV08_RS05370	COG0204	Acyl-transferase
IHV08_RS05375	COG1253	flavin adenine dinucleotide binding
IHV08_RS05380	COG0789	Transcriptional regulator
IHV08_RS05385	COG0436	Aminotransferase
IHV08_RS05390	COG1253	flavin adenine dinucleotide binding
IHV08_RS05395	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IHV08_RS05400	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IHV08_RS05405	COG0584	glycerophosphoryl diester phosphodiesterase
IHV08_RS05415	COG0668	transmembrane transport
IHV08_RS05420	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IHV08_RS05425	COG0726	polysaccharide deacetylase
IHV08_RS05430	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IHV08_RS05435	COG1757	Na H antiporter
IHV08_RS05440	COG0589	response to stress
IHV08_RS05450	COG1132	(ABC) transporter
IHV08_RS05455	COG1132	(ABC) transporter
IHV08_RS05460	COG0702	epimerase
IHV08_RS05480	COG0189	ligase activity
IHV08_RS05485	COG0189	ligase activity
IHV08_RS05490	COG4399	Belongs to the UPF0754 family
IHV08_RS05495	COG3679	Belongs to the UPF0342 family
IHV08_RS05500	COG4335	DNA alkylation repair
IHV08_RS05505	COG0561	phosphatase activity
IHV08_RS05510	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IHV08_RS05515	COG0475	glutathione-regulated potassium exporter activity
IHV08_RS05520	COG0490	domain, Protein
IHV08_RS05530	COG1024	Enoyl-CoA hydratase
IHV08_RS05540	COG4152	abc transporter atp-binding protein
IHV08_RS05545	COG1668	transmembrane transport
IHV08_RS05550	COG0420	3'-5' exonuclease activity
IHV08_RS05555	COG4717	serine-type aminopeptidase activity
IHV08_RS05560	COG3481	metal-dependent phosphohydrolase, HD sub domain
IHV08_RS05570	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IHV08_RS05600	COG1846	Transcriptional regulator
IHV08_RS05605	COG4980	gas vesicle protein
IHV08_RS05620	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IHV08_RS05625	COG0537	adenosine 5'-monophosphoramidase activity
IHV08_RS05630	COG1131	(ABC) transporter
IHV08_RS05635	COG4473	ABC transporter
IHV08_RS05645	COG1473	amidohydrolase
IHV08_RS05650	COG3069	C4-dicarboxylate transmembrane transporter activity
IHV08_RS05660	COG2329	Antibiotic biosynthesis monooxygenase
IHV08_RS05665	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IHV08_RS05670	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IHV08_RS05675	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
IHV08_RS05680	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IHV08_RS05685	COG1309	transcriptional regulator
IHV08_RS05690	COG1511	domain protein
IHV08_RS05695	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IHV08_RS05700	COG4377	Putative membrane peptidase family (DUF2324)
IHV08_RS05710	COG1363	Peptidase, m42
IHV08_RS05715	COG4405	Protein conserved in bacteria
IHV08_RS05720	COG1301	dicarboxylic acid transport
IHV08_RS05730	COG1234	tRNA 3'-trailer cleavage
IHV08_RS05735	COG0095	Lipoate-protein ligase
IHV08_RS05740	COG0702	epimerase
IHV08_RS05745	COG0318	PFAM AMP-dependent synthetase and ligase
IHV08_RS05755	COG0501	Belongs to the peptidase M48B family
IHV08_RS05765	COG0456	acetyltransferase
IHV08_RS05770	COG0604	alcohol dehydrogenase
IHV08_RS05775	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
IHV08_RS05780	COG0406	alpha-ribazole phosphatase activity
IHV08_RS05785	COG0183	Belongs to the thiolase family
IHV08_RS05790	COG0318	PFAM AMP-dependent synthetase and ligase
IHV08_RS05795	COG1268	BioY protein
IHV08_RS05800	COG0840	transmembrane signaling receptor activity
IHV08_RS05805	COG0723	plastoquinol--plastocyanin reductase activity
IHV08_RS05805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IHV08_RS05810	COG1028	Short-chain dehydrogenase reductase Sdr
IHV08_RS05820	COG4903	ComK protein
IHV08_RS05825	COG1028	Short-chain dehydrogenase reductase Sdr
IHV08_RS05835	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IHV08_RS05850	COG0398	Pfam SNARE associated Golgi protein
IHV08_RS05855	COG0681	Belongs to the peptidase S26 family
IHV08_RS05860	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IHV08_RS05865	COG1846	Transcriptional regulator
IHV08_RS05870	COG0738	Major facilitator superfamily
IHV08_RS05875	COG0673	inositol 2-dehydrogenase activity
IHV08_RS05880	COG0561	phosphatase activity
IHV08_RS05885	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IHV08_RS05890	COG1609	Transcriptional regulator
IHV08_RS05895	COG3180	Ammonia monooxygenase
IHV08_RS05900	COG2814	Major facilitator Superfamily
IHV08_RS05900	COG0477	Major facilitator Superfamily
IHV08_RS05905	COG4533	DNA binding
IHV08_RS05915	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
IHV08_RS05920	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
IHV08_RS05925	COG1074	ATP-dependent DNA helicase activity
IHV08_RS05930	COG0420	3'-5' exonuclease activity
IHV08_RS05935	COG0419	ATPase involved in DNA repair
IHV08_RS05940	COG1403	HNH endonuclease
IHV08_RS05980	COG5337	Spore coat protein CotH
IHV08_RS05985	COG0179	Fumarylacetoacetate (FAA) hydrolase
IHV08_RS05995	COG1404	Belongs to the peptidase S8 family
IHV08_RS06005	COG0367	asparagine synthase
IHV08_RS06010	COG2318	DinB family
IHV08_RS06015	COG1562	ergosterol biosynthetic process
IHV08_RS06020	COG0534	Mate efflux family protein
IHV08_RS06025	COG1917	Cupin 2, conserved barrel domain protein
IHV08_RS06025	COG2207	Transcriptional regulator
IHV08_RS06030	COG1609	Transcriptional regulator
IHV08_RS06035	COG0673	inositol 2-dehydrogenase activity
IHV08_RS06040	COG2318	DinB family
IHV08_RS06045	COG1279	arginine transmembrane transporter activity
IHV08_RS06050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IHV08_RS06055	COG1357	PFAM Pentapeptide repeats (8 copies)
IHV08_RS06060	COG2267	carboxylic ester hydrolase activity
IHV08_RS06065	COG0529	Catalyzes the synthesis of activated sulfate
IHV08_RS06070	COG2046	Belongs to the sulfate adenylyltransferase family
IHV08_RS06075	COG0175	sulfate reduction
IHV08_RS06080	COG2045	Belongs to the ComB family
IHV08_RS06085	COG1809	phosphosulfolactate synthase activity
IHV08_RS06090	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IHV08_RS06095	COG4948	Mandelate Racemase Muconate Lactonizing
IHV08_RS06100	COG2814	Major facilitator Superfamily
IHV08_RS06105	COG0454	-acetyltransferase
IHV08_RS06110	COG2153	protein acetylation
IHV08_RS06115	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IHV08_RS06115	COG0646	methionine synthase
IHV08_RS06120	COG1666	GTP binding
IHV08_RS06125	COG2996	Protein conserved in bacteria
IHV08_RS06145	COG1695	Transcriptional regulator
IHV08_RS06160	COG3227	Zinc metalloprotease (Elastase)
IHV08_RS06165	COG1307	EDD domain protein, DegV family
IHV08_RS06170	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IHV08_RS06190	COG0561	phosphatase activity
IHV08_RS06195	COG1073	alpha beta
IHV08_RS06200	COG2151	metal-sulfur cluster biosynthetic enzyme
IHV08_RS06210	COG0277	FAD linked oxidase domain protein
IHV08_RS06215	COG2271	Major facilitator Superfamily
IHV08_RS06220	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IHV08_RS06225	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IHV08_RS06235	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IHV08_RS06240	COG0505	Belongs to the CarA family
IHV08_RS06245	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IHV08_RS06250	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IHV08_RS06265	COG2267	carboxylic ester hydrolase activity
IHV08_RS06275	COG1744	ABC transporter substrate-binding protein PnrA-like
IHV08_RS06290	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IHV08_RS06295	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IHV08_RS06300	COG5504	Zn-dependent protease
IHV08_RS06305	COG0444	Belongs to the ABC transporter superfamily
IHV08_RS06310	COG4608	Belongs to the ABC transporter superfamily
IHV08_RS06320	COG0601	transmembrane transport
IHV08_RS06325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IHV08_RS06335	COG0180	Tryptophanyl-tRNA synthetase
IHV08_RS06340	COG4166	transmembrane transport
IHV08_RS06345	COG0601	transmembrane transport
IHV08_RS06350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IHV08_RS06355	COG0444	Belongs to the ABC transporter superfamily
IHV08_RS06360	COG4608	Belongs to the ABC transporter superfamily
IHV08_RS06365	COG2814	Major facilitator Superfamily
IHV08_RS06370	COG0456	acetyltransferase
IHV08_RS06375	COG1393	Belongs to the ArsC family
IHV08_RS06380	COG0861	Integral membrane protein TerC family
IHV08_RS06390	COG4862	establishment of competence for transformation
IHV08_RS06400	COG4469	Competence protein
IHV08_RS06405	COG1164	Oligoendopeptidase f
IHV08_RS06415	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IHV08_RS06420	COG2346	COG2346, Truncated hemoglobins
IHV08_RS06425	COG0741	lytic transglycosylase activity
IHV08_RS06430	COG4116	CYTH
IHV08_RS06440	COG2357	RelA SpoT domain protein
IHV08_RS06445	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IHV08_RS06450	COG0564	pseudouridine synthase activity
IHV08_RS06455	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IHV08_RS06460	COG0475	glutathione-regulated potassium exporter activity
IHV08_RS06460	COG0569	domain protein
IHV08_RS06465	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IHV08_RS06470	COG0352	thiamine-phosphate diphosphorylase activity
IHV08_RS06475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IHV08_RS06480	COG2104	thiamine diphosphate biosynthetic process
IHV08_RS06485	COG2022	thiamine diphosphate biosynthetic process
IHV08_RS06490	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IHV08_RS06495	COG0351	phosphomethylpyrimidine kinase
IHV08_RS06500	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IHV08_RS06555	COG0210	DNA helicase
IHV08_RS06565	COG2153	protein acetylation
IHV08_RS06570	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IHV08_RS06575	COG2382	esterase
IHV08_RS06580	COG0626	cystathionine gamma-synthase activity
IHV08_RS06585	COG0626	cystathionine gamma-synthase activity
IHV08_RS06590	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IHV08_RS06595	COG5505	Protein of unknown function (DUF819)
IHV08_RS06615	COG5444	nuclease activity
IHV08_RS06640	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IHV08_RS06645	COG1028	Short-chain dehydrogenase reductase Sdr
IHV08_RS06655	COG3711	transcriptional antiterminator
IHV08_RS06655	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IHV08_RS06660	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IHV08_RS06660	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IHV08_RS06660	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IHV08_RS06665	COG1482	cell wall glycoprotein biosynthetic process
IHV08_RS06675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IHV08_RS06685	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IHV08_RS06700	COG0109	protoheme IX farnesyltransferase activity
IHV08_RS06710	COG0726	polysaccharide deacetylase
IHV08_RS06725	COG5504	Zn-dependent protease
IHV08_RS06730	COG2205	protein histidine kinase activity
IHV08_RS06740	COG3383	formate dehydrogenase (NAD+) activity
IHV08_RS06745	COG2427	Protein of unknown function (DUF1641)
IHV08_RS06755	COG1051	belongs to the nudix hydrolase family
IHV08_RS06770	COG1819	glycosyl
IHV08_RS06780	COG1587	Uroporphyrinogen-III synthase
IHV08_RS06785	COG0390	transport system, permease component
IHV08_RS06790	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IHV08_RS06795	COG0697	spore germination
IHV08_RS06800	COG4297	protein containing double-stranded beta helix domain
IHV08_RS06810	COG1252	NADH dehydrogenase
IHV08_RS06815	COG1904	glucuronate isomerase
IHV08_RS06820	COG2211	Major facilitator Superfamily
IHV08_RS06825	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
IHV08_RS06830	COG1063	alcohol dehydrogenase
IHV08_RS06835	COG1312	Catalyzes the dehydration of D-mannonate
IHV08_RS06840	COG1028	Short-chain dehydrogenase reductase Sdr
IHV08_RS06845	COG2271	Major facilitator Superfamily
IHV08_RS06850	COG1609	Transcriptional regulator
IHV08_RS06855	COG0246	Mannitol dehydrogenase
IHV08_RS06860	COG2721	sulfolactate sulfo-lyase activity
IHV08_RS06865	COG0730	response to heat
IHV08_RS06870	COG2318	DinB family
IHV08_RS06875	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IHV08_RS06880	COG0457	Tetratricopeptide repeat
IHV08_RS06890	COG2350	Protein conserved in bacteria
IHV08_RS06895	COG1388	LysM domain
IHV08_RS06895	COG3409	Peptidoglycan-binding domain 1 protein
IHV08_RS06895	COG5632	N-Acetylmuramoyl-L-alanine amidase
IHV08_RS06905	COG4195	phage-related replication protein
IHV08_RS06910	COG3546	catalase activity
IHV08_RS06915	COG2856	Zn peptidase
IHV08_RS06920	COG1396	sequence-specific DNA binding
IHV08_RS06930	COG1522	sequence-specific DNA binding
IHV08_RS06935	COG1484	DNA-dependent DNA replication
IHV08_RS06955	COG1595	DNA-templated transcription, initiation
IHV08_RS06960	COG3728	DNA packaging
IHV08_RS06960	COG5484	DNA packaging
IHV08_RS06965	COG1783	phage Terminase large subunit
IHV08_RS06970	COG5518	Phage portal protein
IHV08_RS06975	COG0338	D12 class N6 adenine-specific DNA methyltransferase
IHV08_RS06980	COG4653	Phage capsid family
IHV08_RS07030	COG3953	SLT domain
IHV08_RS07030	COG5412	phage tail tape measure protein
IHV08_RS07035	COG1652	LysM domain
IHV08_RS07040	COG4193	domain, Protein
IHV08_RS07050	COG3628	GPW Gp25 family protein
IHV08_RS07055	COG3299	homolog of phage Mu protein gp47
IHV08_RS07060	COG3778	Protein conserved in bacteria
IHV08_RS07100	COG3409	Peptidoglycan-binding domain 1 protein
IHV08_RS07100	COG5632	N-Acetylmuramoyl-L-alanine amidase
IHV08_RS07105	COG3594	Acyltransferase
IHV08_RS07125	COG0306	phosphate transporter
IHV08_RS07130	COG1392	Phosphate transport regulator
IHV08_RS07135	COG0531	amino acid
IHV08_RS07140	COG0346	lactoylglutathione lyase activity
IHV08_RS07150	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IHV08_RS07155	COG0463	Glycosyl transferase, family 2
IHV08_RS07160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IHV08_RS07165	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IHV08_RS07170	COG2362	D-Aminopeptidase
IHV08_RS07175	COG0601	transmembrane transport
IHV08_RS07180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IHV08_RS07185	COG0444	Belongs to the ABC transporter superfamily
IHV08_RS07190	COG4166	transmembrane transport
IHV08_RS07195	COG1619	proteins homologs of microcin C7 resistance protein MccF
IHV08_RS07200	COG4948	Mandelate Racemase Muconate Lactonizing
IHV08_RS07205	COG0791	NLP P60 protein
IHV08_RS07210	COG4608	Belongs to the ABC transporter superfamily
IHV08_RS07215	COG2706	6-phosphogluconolactonase activity
IHV08_RS07220	COG1834	amidinotransferase
IHV08_RS07225	COG1607	acyl-coa hydrolase
IHV08_RS07230	COG1017	nitric oxide dioxygenase activity
IHV08_RS07230	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IHV08_RS07240	COG2323	membrane
IHV08_RS07245	COG2318	DinB family
IHV08_RS07250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IHV08_RS07255	COG2076	Multidrug Resistance protein
IHV08_RS07260	COG2076	Multidrug Resistance protein
IHV08_RS07265	COG0788	formyltetrahydrofolate deformylase activity
IHV08_RS07270	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IHV08_RS07275	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IHV08_RS07280	COG1764	response to oxidative stress
IHV08_RS07285	COG1846	Transcriptional regulator
IHV08_RS07290	COG1764	response to oxidative stress
IHV08_RS07300	COG0590	tRNA wobble adenosine to inosine editing
IHV08_RS07305	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IHV08_RS07310	COG1404	Belongs to the peptidase S8 family
IHV08_RS07315	COG1366	Belongs to the anti-sigma-factor antagonist family
IHV08_RS07320	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IHV08_RS07325	COG1122	ATPase activity
IHV08_RS07330	COG4721	ABC-type cobalt transport system, permease component
IHV08_RS07340	COG0745	RESPONSE REGULATOR receiver
IHV08_RS07345	COG3850	Histidine kinase
IHV08_RS07345	COG5002	protein histidine kinase activity
IHV08_RS07350	COG3212	peptidase
IHV08_RS07355	COG3212	peptidase
IHV08_RS07365	COG2239	Acts as a magnesium transporter
IHV08_RS07370	COG0789	Transcriptional regulator
IHV08_RS07385	COG1846	Transcriptional regulator
IHV08_RS07390	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IHV08_RS07395	COG0726	polysaccharide deacetylase
IHV08_RS07400	COG1408	metallophosphoesterase
IHV08_RS07410	COG0463	Glycosyl transferase, family 2
IHV08_RS07415	COG3285	dna ligase
IHV08_RS07415	COG1793	dna ligase
IHV08_RS07420	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
IHV08_RS07425	COG3300	MHYT domain
IHV08_RS07425	COG5001	Diguanylate cyclase
IHV08_RS07430	COG0586	Pfam SNARE associated Golgi protein
IHV08_RS07435	COG0861	Integral membrane protein TerC family
IHV08_RS07440	COG1191	sigma factor activity
IHV08_RS07460	COG0501	Belongs to the peptidase M48B family
IHV08_RS07465	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IHV08_RS07480	COG3594	Acyltransferase
IHV08_RS07485	COG5002	protein histidine kinase activity
IHV08_RS07490	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IHV08_RS07500	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IHV08_RS07505	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
IHV08_RS07510	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IHV08_RS07515	COG0436	Aminotransferase
IHV08_RS07520	COG1850	ribulose-bisphosphate carboxylase activity
IHV08_RS07525	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
IHV08_RS07530	COG0235	Class ii aldolase
IHV08_RS07535	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
IHV08_RS07540	COG3339	Conserved Protein
IHV08_RS07555	COG3852	Histidine kinase
IHV08_RS07560	COG1846	Transcriptional regulator
IHV08_RS07565	COG1360	Flagellar Motor Protein
IHV08_RS07570	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IHV08_RS07575	COG0542	response to heat
IHV08_RS07580	COG3949	Membrane
IHV08_RS07585	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IHV08_RS07590	COG0720	synthase
IHV08_RS07595	COG0602	queuosine metabolic process
IHV08_RS07600	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IHV08_RS07605	COG1733	regulation of RNA biosynthetic process
IHV08_RS07610	COG1028	Short-chain dehydrogenase reductase Sdr
IHV08_RS07615	COG1388	LysM domain
IHV08_RS07615	COG4641	Protein conserved in bacteria
IHV08_RS07620	COG1388	LysM domain
IHV08_RS07625	COG3858	chitin binding
IHV08_RS07635	COG4873	Protein conserved in bacteria
IHV08_RS07645	COG3773	Cell wall hydrolase
IHV08_RS07650	COG2244	polysaccharide biosynthetic process
IHV08_RS07655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IHV08_RS07660	COG2217	Heavy metal translocating P-type atpase
IHV08_RS07670	COG0006	proline dipeptidase activity
IHV08_RS07675	COG1609	Transcriptional regulator
IHV08_RS07680	COG3711	transcriptional antiterminator
IHV08_RS07685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IHV08_RS07685	COG1263	PTS System
IHV08_RS07685	COG2190	(PTS) system
IHV08_RS07690	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IHV08_RS07695	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IHV08_RS07705	COG1533	DNA photolyase activity
IHV08_RS07710	COG0456	acetyltransferase
IHV08_RS07715	COG0840	transmembrane signaling receptor activity
IHV08_RS07720	COG2084	Dehydrogenase
IHV08_RS07725	COG2340	Cysteine-rich secretory protein family
IHV08_RS07730	COG0768	penicillin binding
IHV08_RS07735	COG4191	Histidine kinase
IHV08_RS07740	COG0436	Aminotransferase
IHV08_RS07750	COG0835	chemotaxis
IHV08_RS07750	COG0784	Response regulator, receiver
IHV08_RS07760	COG2814	Major facilitator Superfamily
IHV08_RS07765	COG1376	ErfK ybiS ycfS ynhG family protein
IHV08_RS07770	COG1408	metallophosphoesterase
IHV08_RS07775	COG1028	Short-chain dehydrogenase reductase Sdr
IHV08_RS07780	COG2200	EAL domain
IHV08_RS07785	COG4703	Protein of unknown function (DUF1797)
IHV08_RS07790	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
IHV08_RS07800	COG0517	IMP dehydrogenase activity
IHV08_RS07805	COG0583	DNA-binding transcription factor activity
IHV08_RS07810	COG0716	FMN binding
IHV08_RS07820	COG0716	FMN binding
IHV08_RS07825	COG2171	N-acyltransferase activity
IHV08_RS07830	COG1473	amidohydrolase
IHV08_RS07840	COG0668	transmembrane transport
IHV08_RS07845	COG0450	alkyl hydroperoxide reductase
IHV08_RS07850	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IHV08_RS07865	COG0746	molybdenum cofactor guanylyltransferase activity
IHV08_RS07870	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IHV08_RS07875	COG0303	'Molybdopterin
IHV08_RS07880	COG1763	Mo-molybdopterin cofactor biosynthetic process
IHV08_RS07885	COG0314	molybdopterin synthase activity
IHV08_RS07890	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IHV08_RS07895	COG1132	(ABC) transporter
IHV08_RS07900	COG1132	(ABC) transporter
IHV08_RS07910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IHV08_RS07915	COG1136	(ABC) transporter
IHV08_RS07920	COG0577	efflux transmembrane transporter activity
IHV08_RS07925	COG1349	DNA-binding transcription factor activity
IHV08_RS07930	COG1105	Belongs to the carbohydrate kinase PfkB family
IHV08_RS07935	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IHV08_RS07935	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IHV08_RS07935	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IHV08_RS07940	COG0681	Belongs to the peptidase S26 family
IHV08_RS07950	COG0488	(ABC) transporter
IHV08_RS07955	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IHV08_RS07960	COG2309	aminopeptidase activity
IHV08_RS07970	COG1077	Cell shape determining protein MreB Mrl
IHV08_RS07975	COG2002	toxin-antitoxin pair type II binding
IHV08_RS07980	COG3852	Histidine kinase
IHV08_RS07985	COG2105	PFAM AIG2 family protein
IHV08_RS07985	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
IHV08_RS07990	COG0569	domain protein
IHV08_RS07995	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IHV08_RS08000	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IHV08_RS08005	COG5503	Protein of unknown function (DUF1447)
IHV08_RS08010	COG0561	phosphatase activity
IHV08_RS08015	COG0242	peptide deformylase activity
IHV08_RS08025	COG0497	DNA recombination
IHV08_RS08030	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IHV08_RS08035	COG0022	dehydrogenase e1 component
IHV08_RS08040	COG0508	dehydrogenase complex catalyzes the overall conversion of
IHV08_RS08045	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IHV08_RS08050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IHV08_RS08060	COG1982	Orn Lys Arg decarboxylase major
IHV08_RS08065	COG4476	Belongs to the UPF0223 family
IHV08_RS08070	COG4493	Belongs to the UPF0637 family
IHV08_RS08080	COG0483	inositol monophosphate 1-phosphatase activity
IHV08_RS08090	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IHV08_RS08110	COG1595	DNA-templated transcription, initiation
IHV08_RS08130	COG1217	gtp-binding protein TYPA
IHV08_RS08140	COG4896	Protein conserved in bacteria
IHV08_RS08150	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IHV08_RS08155	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IHV08_RS08160	COG2066	Belongs to the glutaminase family
IHV08_RS08165	COG4838	Belongs to the UPF0358 family
IHV08_RS08170	COG0772	Belongs to the SEDS family
IHV08_RS08175	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IHV08_RS08180	COG1612	heme a metabolic process
IHV08_RS08185	COG0109	protoheme IX farnesyltransferase activity
IHV08_RS08190	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IHV08_RS08190	COG2010	Cytochrome c
IHV08_RS08195	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IHV08_RS08200	COG1845	cytochrome c oxidase, subunit III
IHV08_RS08205	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IHV08_RS08210	COG3336	cytochrome c oxidase
IHV08_RS08220	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
IHV08_RS08225	COG2340	Cysteine-rich secretory protein family
IHV08_RS08240	COG3679	Belongs to the UPF0342 family
IHV08_RS08245	COG4471	UPF0298 protein
IHV08_RS08250	COG0742	ribosomal rna small subunit methyltransferase
IHV08_RS08255	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IHV08_RS08260	COG3314	Sporulation integral membrane protein YlbJ
IHV08_RS08265	COG1752	Esterase of the alpha-beta hydrolase superfamily
IHV08_RS08270	COG3480	Lon protease (S16) C-terminal proteolytic domain
IHV08_RS08275	COG1323	Belongs to the UPF0348 family
IHV08_RS08285	COG1399	metal-binding, possibly nucleic acid-binding protein
IHV08_RS08300	COG0454	-acetyltransferase
IHV08_RS08305	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IHV08_RS08310	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
IHV08_RS08315	COG2001	Belongs to the MraZ family
IHV08_RS08320	COG0275	rRNA processing
IHV08_RS08325	COG4839	cell division protein FtsL
IHV08_RS08330	COG0768	penicillin binding
IHV08_RS08335	COG0768	penicillin binding
IHV08_RS08340	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IHV08_RS08345	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IHV08_RS08350	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IHV08_RS08355	COG0772	Belongs to the SEDS family
IHV08_RS08360	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IHV08_RS08365	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IHV08_RS08370	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IHV08_RS08375	COG3879	Bacterial protein of unknown function (DUF881)
IHV08_RS08380	COG3879	Bacterial protein of unknown function (DUF881)
IHV08_RS08385	COG3856	small basic protein
IHV08_RS08390	COG0849	cell division
IHV08_RS08395	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IHV08_RS08410	COG4412	M6 family metalloprotease domain protein
IHV08_RS08410	COG1404	Belongs to the peptidase S8 family
IHV08_RS08420	COG1191	sigma factor activity
IHV08_RS08425	COG1191	sigma factor activity
IHV08_RS08430	COG1119	ATPase activity
IHV08_RS08435	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IHV08_RS08440	COG1873	PFAM PRC-barrel domain
IHV08_RS08445	COG1496	oxidoreductase activity
IHV08_RS08450	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IHV08_RS08455	COG1799	cell septum assembly
IHV08_RS08460	COG0762	integral membrane protein
IHV08_RS08465	COG2302	S4 RNA-binding domain
IHV08_RS08470	COG3599	regulation of cell shape
IHV08_RS08475	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IHV08_RS08480	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IHV08_RS08485	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IHV08_RS08490	COG0564	pseudouridine synthase activity
IHV08_RS08495	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IHV08_RS08500	COG2233	PERMEase
IHV08_RS08505	COG0540	Belongs to the ATCase OTCase family
IHV08_RS08510	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IHV08_RS08515	COG0505	Belongs to the CarA family
IHV08_RS08520	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IHV08_RS08525	COG0543	2 iron, 2 sulfur cluster binding
IHV08_RS08530	COG0167	dihydroorotate dehydrogenase activity
IHV08_RS08535	COG0284	orotidine-5'-phosphate decarboxylase activity
IHV08_RS08540	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IHV08_RS08545	COG0175	sulfate reduction
IHV08_RS08550	COG0306	phosphate transporter
IHV08_RS08555	COG2046	Belongs to the sulfate adenylyltransferase family
IHV08_RS08560	COG0529	Catalyzes the synthesis of activated sulfate
IHV08_RS08565	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IHV08_RS08570	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
IHV08_RS08575	COG1648	precorrin-2 dehydrogenase activity
IHV08_RS08580	COG1293	RNA-binding protein homologous to eukaryotic snRNP
IHV08_RS08585	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IHV08_RS08590	COG1561	YicC-like family, N-terminal region
IHV08_RS08600	COG0194	GDP metabolic process
IHV08_RS08605	COG1758	RNA polymerase activity
IHV08_RS08610	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IHV08_RS08615	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IHV08_RS08620	COG0242	peptide deformylase activity
IHV08_RS08625	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IHV08_RS08630	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IHV08_RS08630	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IHV08_RS08635	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IHV08_RS08640	COG0631	protein serine/threonine phosphatase activity
IHV08_RS08645	COG2815	serine threonine protein kinase
IHV08_RS08645	COG0515	serine threonine protein kinase
IHV08_RS08650	COG1162	GTPase activity
IHV08_RS08655	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IHV08_RS08660	COG1564	THIamine pyrophosphokinase
IHV08_RS08670	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IHV08_RS08675	COG1302	Protein conserved in bacteria
IHV08_RS08680	COG1461	Dihydroxyacetone kinase
IHV08_RS08685	COG1760	l-serine dehydratase
IHV08_RS08690	COG1760	l-serine dehydratase
IHV08_RS08695	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IHV08_RS08700	COG1349	DNA-binding transcription factor activity
IHV08_RS08700	COG2050	protein possibly involved in aromatic compounds catabolism
IHV08_RS08705	COG0416	fatty acid biosynthetic process
IHV08_RS08710	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IHV08_RS08715	COG1028	Short-chain dehydrogenase reductase Sdr
IHV08_RS08725	COG0571	ribonuclease III activity
IHV08_RS08730	COG1196	nuclear chromosome segregation
IHV08_RS08735	COG0552	protein localization to endoplasmic reticulum
IHV08_RS08745	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IHV08_RS08750	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IHV08_RS08755	COG0228	four-way junction DNA binding
IHV08_RS08760	COG1837	Belongs to the UPF0109 family
IHV08_RS08770	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IHV08_RS08775	COG0336	Belongs to the RNA methyltransferase TrmD family
IHV08_RS08780	COG0335	large ribosomal subunit rRNA binding
IHV08_RS08785	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IHV08_RS08790	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IHV08_RS08800	COG2257	FlhB HrpN YscU SpaS Family
IHV08_RS08805	COG0045	succinate-CoA ligase (ADP-forming) activity
IHV08_RS08810	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IHV08_RS08815	COG0758	DNA mediated transformation
IHV08_RS08820	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IHV08_RS08825	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IHV08_RS08830	COG4974	Belongs to the 'phage' integrase family
IHV08_RS08835	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IHV08_RS08840	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IHV08_RS08845	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IHV08_RS08850	COG1815	bacterial-type flagellum-dependent cell motility
IHV08_RS08855	COG1558	bacterial-type flagellum-dependent cell motility
IHV08_RS08860	COG1677	Flagellar hook-basal body complex protein FliE
IHV08_RS08865	COG1766	The M ring may be actively involved in energy transduction
IHV08_RS08870	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IHV08_RS08875	COG1317	bacterial-type flagellum organization
IHV08_RS08880	COG1157	protein secretion by the type III secretion system
IHV08_RS08885	COG2882	bacterial-type flagellum organization
IHV08_RS08890	COG3334	PFAM MgtE intracellular
IHV08_RS08895	COG3144	bacterial-type flagellum assembly
IHV08_RS08900	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
IHV08_RS08905	COG4786	Flagellar basal body rod
IHV08_RS08910	COG1582	Flagellar protein (FlbD)
IHV08_RS08915	COG1580	Controls the rotational direction of flagella during chemotaxis
IHV08_RS08920	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IHV08_RS08925	COG1776	CheC inhibitor of MCP methylation
IHV08_RS08925	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IHV08_RS08930	COG2201	protein-glutamate methylesterase activity
IHV08_RS08935	COG3190	flagellar
IHV08_RS08940	COG1338	Plays a role in the flagellum-specific transport system
IHV08_RS08945	COG1987	bacterial-type flagellum assembly
IHV08_RS08950	COG1684	flagellar biosynthetic protein fliR
IHV08_RS08955	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IHV08_RS08960	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IHV08_RS08965	COG1419	protein localization to endoplasmic reticulum
IHV08_RS08970	COG0455	bacterial-type flagellum organization
IHV08_RS08975	COG2201	protein-glutamate methylesterase activity
IHV08_RS08980	COG0643	Histidine kinase
IHV08_RS08980	COG2198	Histidine kinase
IHV08_RS08985	COG0835	chemotaxis
IHV08_RS08990	COG1776	CheC inhibitor of MCP methylation
IHV08_RS08995	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
IHV08_RS09000	COG1191	sigma factor activity
IHV08_RS09010	COG0052	Belongs to the universal ribosomal protein uS2 family
IHV08_RS09015	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IHV08_RS09020	COG0528	UMP kinase activity
IHV08_RS09025	COG0233	cytoplasmic translational termination
IHV08_RS09030	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IHV08_RS09035	COG4589	Belongs to the CDS family
IHV08_RS09040	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
IHV08_RS09045	COG0750	zinc metalloprotease
IHV08_RS09050	COG0442	prolyl-tRNA aminoacylation
IHV08_RS09055	COG2176	DNA-directed DNA polymerase activity
IHV08_RS09060	COG0779	Required for maturation of 30S ribosomal subunits
IHV08_RS09065	COG0195	Participates in both transcription termination and antitermination
IHV08_RS09070	COG2740	Nucleic-acid-binding protein implicated in transcription termination
IHV08_RS09075	COG1358	cellular component organization or biogenesis
IHV08_RS09080	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IHV08_RS09085	COG1550	Protein conserved in bacteria
IHV08_RS09090	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IHV08_RS09095	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IHV08_RS09100	COG0196	riboflavin kinase activity
IHV08_RS09105	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IHV08_RS09110	COG1185	polyribonucleotide nucleotidyltransferase activity
IHV08_RS09115	COG0726	polysaccharide deacetylase
IHV08_RS09120	COG0612	Peptidase, M16
IHV08_RS09125	COG1873	PFAM PRC-barrel domain
IHV08_RS09130	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IHV08_RS09135	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IHV08_RS09140	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IHV08_RS09145	COG0527	aspartate kinase activity
IHV08_RS09150	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IHV08_RS09155	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IHV08_RS09160	COG0740	serine-type endopeptidase activity
IHV08_RS09170	COG1674	ftsk spoiiie
IHV08_RS09170	COG4980	gas vesicle protein
IHV08_RS09175	COG2188	Transcriptional regulator
IHV08_RS09180	COG2814	Major facilitator Superfamily
IHV08_RS09185	COG0612	Peptidase, M16
IHV08_RS09190	COG0612	Peptidase, M16
IHV08_RS09195	COG0300	oxidoreductase activity
IHV08_RS09210	COG1426	Protein conserved in bacteria
IHV08_RS09215	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IHV08_RS09220	COG1058	Belongs to the CinA family
IHV08_RS09220	COG1546	Belongs to the CinA family
IHV08_RS09225	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IHV08_RS09230	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IHV08_RS09235	COG1418	mRNA catabolic process
IHV08_RS09240	COG1692	metallophosphoesterase
IHV08_RS09245	COG2359	stage V sporulation protein S
IHV08_RS09250	COG1063	alcohol dehydrogenase
IHV08_RS09255	COG0156	8-amino-7-oxononanoate synthase activity
IHV08_RS09260	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IHV08_RS09265	COG4550	Control of competence regulator ComK, YlbF/YmcA
IHV08_RS09275	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IHV08_RS09280	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IHV08_RS09295	COG3226	Transcriptional regulator
IHV08_RS09300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IHV08_RS09310	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IHV08_RS09315	COG3321	synthase
IHV08_RS09320	COG2070	2-Nitropropane dioxygenase
IHV08_RS09320	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IHV08_RS09325	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IHV08_RS09330	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IHV08_RS09335	COG3425	synthase
IHV08_RS09340	COG1024	Enoyl-CoA hydratase
IHV08_RS09345	COG1024	Enoyl-CoA hydratase
IHV08_RS09350	COG0300	oxidoreductase activity
IHV08_RS09350	COG3321	synthase
IHV08_RS09350	COG1028	Short-chain dehydrogenase reductase Sdr
IHV08_RS09350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IHV08_RS09350	COG0318	PFAM AMP-dependent synthetase and ligase
IHV08_RS09355	COG3321	synthase
IHV08_RS09355	COG4221	oxidoreductase activity
IHV08_RS09355	COG0300	oxidoreductase activity
IHV08_RS09355	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IHV08_RS09360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IHV08_RS09360	COG1028	Short-chain dehydrogenase reductase Sdr
IHV08_RS09360	COG3321	synthase
IHV08_RS09360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IHV08_RS09360	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IHV08_RS09365	COG4221	oxidoreductase activity
IHV08_RS09365	COG3321	synthase
IHV08_RS09365	COG1028	Short-chain dehydrogenase reductase Sdr
IHV08_RS09365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IHV08_RS09370	COG3321	synthase
IHV08_RS09370	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IHV08_RS09370	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IHV08_RS09370	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
IHV08_RS09375	COG2124	cytochrome p450
IHV08_RS09385	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IHV08_RS09390	COG1404	Belongs to the peptidase S8 family
IHV08_RS09400	COG4195	phage-related replication protein
IHV08_RS09405	COG1764	response to oxidative stress
IHV08_RS09410	COG2076	Multidrug Resistance protein
IHV08_RS09415	COG2076	Multidrug Resistance protein
IHV08_RS09430	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IHV08_RS09435	COG1923	regulation of RNA biosynthetic process
IHV08_RS09450	COG1780	Probably involved in ribonucleotide reductase function
IHV08_RS09455	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IHV08_RS09460	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IHV08_RS09465	COG4112	unkown
IHV08_RS09470	COG0860	N-Acetylmuramoyl-L-alanine amidase
IHV08_RS09475	COG0464	growth
IHV08_RS09480	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IHV08_RS09485	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
IHV08_RS09490	COG0789	Transcriptional regulator
IHV08_RS09495	COG0174	glutamine synthetase
IHV08_RS09515	COG4282	regulation of fungal-type cell wall biogenesis
IHV08_RS09530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IHV08_RS09550	COG3655	Transcriptional regulator
IHV08_RS09580	COG2211	Major facilitator Superfamily
IHV08_RS09585	COG3507	Belongs to the glycosyl hydrolase 43 family
IHV08_RS09590	COG1940	carbohydrate kinase activity
IHV08_RS09595	COG2115	Belongs to the xylose isomerase family
IHV08_RS09600	COG1070	Carbohydrate kinase
IHV08_RS09610	COG1525	nuclease
IHV08_RS09615	COG2814	Major facilitator Superfamily
IHV08_RS09620	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IHV08_RS09630	COG0756	dUTP diphosphatase activity
IHV08_RS09670	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IHV08_RS09685	COG3832	glyoxalase III activity
IHV08_RS09725	COG4195	phage-related replication protein
IHV08_RS09735	COG0346	lactoylglutathione lyase activity
IHV08_RS09740	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IHV08_RS09745	COG1388	LysM domain
IHV08_RS09750	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IHV08_RS09755	COG4224	UPF0291 protein
IHV08_RS09760	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IHV08_RS09770	COG3763	UPF0154 protein
IHV08_RS09780	COG0785	Cytochrome C biogenesis protein
IHV08_RS09785	COG2201	protein-glutamate methylesterase activity
IHV08_RS09790	COG4846	Membrane protein involved in cytochrome C biogenesis
IHV08_RS09800	COG0071	Belongs to the small heat shock protein (HSP20) family
IHV08_RS09815	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IHV08_RS09820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IHV08_RS09840	COG0824	Thioesterase
IHV08_RS09850	COG4841	protein insertion into membrane
IHV08_RS09855	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
IHV08_RS09860	COG1832	CoA-binding protein
IHV08_RS09865	COG0187	DNA topoisomerase II activity
IHV08_RS09870	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IHV08_RS09880	COG1115	amino acid carrier protein
IHV08_RS09885	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IHV08_RS09895	COG5520	Belongs to the glycosyl hydrolase 30 family
IHV08_RS09900	COG3507	Belongs to the glycosyl hydrolase 43 family
IHV08_RS09905	COG2246	polysaccharide biosynthetic process
IHV08_RS09910	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IHV08_RS09915	COG0586	Pfam SNARE associated Golgi protein
IHV08_RS09920	COG2404	hydrolase activity, acting on ester bonds
IHV08_RS09925	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IHV08_RS09930	COG1024	Enoyl-CoA hydratase
IHV08_RS09935	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IHV08_RS09940	COG0511	ligase activity, forming carbon-carbon bonds
IHV08_RS09945	COG0439	Biotin carboxylase
IHV08_RS09950	COG0318	PFAM AMP-dependent synthetase and ligase
IHV08_RS09955	COG1960	acyl-CoA dehydrogenase activity
IHV08_RS09970	COG1649	PFAM Uncharacterised BCR, COG1649
IHV08_RS09980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IHV08_RS09980	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
IHV08_RS09985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IHV08_RS09990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IHV08_RS09995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IHV08_RS10000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IHV08_RS10010	COG2027	D-alanyl-D-alanine carboxypeptidase
IHV08_RS10015	COG2017	converts alpha-aldose to the beta-anomer
IHV08_RS10020	COG0534	Mate efflux family protein
IHV08_RS10035	COG0582	viral genome integration into host DNA
IHV08_RS10040	COG0166	Belongs to the GPI family
IHV08_RS10045	COG0405	Gamma-glutamyltransferase
IHV08_RS10050	COG0583	DNA-binding transcription factor activity
IHV08_RS10055	COG0604	alcohol dehydrogenase
IHV08_RS10060	COG0493	'glutamate synthase
IHV08_RS10065	COG0069	glutamate synthase activity
IHV08_RS10065	COG0067	glutamate synthase
IHV08_RS10065	COG0070	glutamate synthase
IHV08_RS10070	COG0583	DNA-binding transcription factor activity
IHV08_RS10075	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IHV08_RS10080	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IHV08_RS10090	COG0300	oxidoreductase activity
IHV08_RS10095	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IHV08_RS10105	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IHV08_RS10120	COG1131	(ABC) transporter
IHV08_RS10130	COG2814	Major facilitator Superfamily
IHV08_RS10135	COG1070	Carbohydrate kinase
IHV08_RS10140	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IHV08_RS10145	COG0243	molybdopterin cofactor binding
IHV08_RS10175	COG0840	transmembrane signaling receptor activity
IHV08_RS10175	COG5278	phosphoserine phosphatase activity
IHV08_RS10180	COG2368	4-hydroxyphenylacetate
IHV08_RS10185	COG4305	rare lipoprotein A
IHV08_RS10190	COG3619	membrane
IHV08_RS10195	COG3866	Pectate lyase
IHV08_RS10200	COG2135	peptidase activity
IHV08_RS10225	COG0456	acetyltransferase
IHV08_RS10245	COG2720	vancomycin resistance protein
IHV08_RS10260	COG3739	integral membrane protein
IHV08_RS10265	COG0583	DNA-binding transcription factor activity
IHV08_RS10270	COG0697	spore germination
IHV08_RS10280	COG0693	protein deglycase activity
IHV08_RS10285	COG2367	Beta-lactamase
IHV08_RS10305	COG0574	Belongs to the PEP-utilizing enzyme family
IHV08_RS10305	COG3848	Pyruvate phosphate dikinase
IHV08_RS10310	COG0726	polysaccharide deacetylase
IHV08_RS10315	COG1793	dna ligase
IHV08_RS10350	COG5444	nuclease activity
IHV08_RS10355	COG4282	regulation of fungal-type cell wall biogenesis
IHV08_RS10360	COG1231	oxidoreductase activity
IHV08_RS10365	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IHV08_RS10370	COG0662	Cupin 2, conserved barrel domain protein
IHV08_RS10370	COG2207	Transcriptional regulator
IHV08_RS10375	COG0456	acetyltransferase
IHV08_RS10380	COG1309	transcriptional regulator
IHV08_RS10385	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IHV08_RS10390	COG3708	Transcriptional regulator
IHV08_RS10395	COG2378	regulation of single-species biofilm formation
IHV08_RS10405	COG0640	Transcriptional regulator
IHV08_RS10410	COG0741	lytic transglycosylase activity
IHV08_RS10415	COG2322	membrane
IHV08_RS10430	COG1619	proteins homologs of microcin C7 resistance protein MccF
IHV08_RS10435	COG3239	Fatty acid desaturase
IHV08_RS10440	COG4585	Histidine kinase
IHV08_RS10445	COG2197	response regulator
IHV08_RS10450	COG1388	LysM domain
IHV08_RS10450	COG3584	3D domain protein
IHV08_RS10455	COG0514	ATP-dependent DNA helicase (RecQ)
IHV08_RS10465	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IHV08_RS10470	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IHV08_RS10485	COG0071	Belongs to the small heat shock protein (HSP20) family
IHV08_RS10510	COG1012	belongs to the aldehyde dehydrogenase family
IHV08_RS10515	COG1657	PFAM Prenyltransferase squalene oxidase
IHV08_RS10520	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IHV08_RS10525	COG0733	neurotransmitter:sodium symporter activity
IHV08_RS10530	COG0385	Bile acid
IHV08_RS10535	COG0508	dehydrogenase complex catalyzes the overall conversion of
IHV08_RS10540	COG0567	Dehydrogenase, E1 component
IHV08_RS10545	COG4548	von Willebrand factor, type A
IHV08_RS10550	COG0714	Associated with various cellular activities
IHV08_RS10555	COG2032	superoxide dismutase activity
IHV08_RS10560	COG0791	NLP P60 protein
IHV08_RS10560	COG1388	LysM domain
IHV08_RS10565	COG1819	glycosyl
IHV08_RS10570	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IHV08_RS10575	COG0534	Mate efflux family protein
IHV08_RS10580	COG1366	Belongs to the anti-sigma-factor antagonist family
IHV08_RS10585	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IHV08_RS10590	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IHV08_RS10600	COG2962	Rard protein
IHV08_RS10620	COG1942	4-Oxalocrotonate Tautomerase
IHV08_RS10625	COG1733	regulation of RNA biosynthetic process
IHV08_RS10630	COG0778	Nitroreductase
IHV08_RS10635	COG0400	carboxylic ester hydrolase activity
IHV08_RS10640	COG0346	lactoylglutathione lyase activity
IHV08_RS10650	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IHV08_RS10655	COG3409	Peptidoglycan-binding domain 1 protein
IHV08_RS10655	COG0793	Belongs to the peptidase S41A family
IHV08_RS10660	COG2226	methyltransferase
IHV08_RS10670	COG1876	peptidase activity
IHV08_RS10675	COG0813	purine-nucleoside phosphorylase activity
IHV08_RS10690	COG0671	phosphoesterase, PA-phosphatase related
IHV08_RS10710	COG4479	Belongs to the UPF0346 family
IHV08_RS10720	COG1509	lysine 2,3-aminomutase activity
IHV08_RS10725	COG0456	acetyltransferase
IHV08_RS10730	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IHV08_RS10735	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IHV08_RS10740	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IHV08_RS10745	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IHV08_RS10760	COG0456	acetyltransferase
IHV08_RS10765	COG0463	Glycosyl transferase, family 2
IHV08_RS10780	COG4641	Protein conserved in bacteria
IHV08_RS10785	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
IHV08_RS10790	COG1086	Polysaccharide biosynthesis protein
IHV08_RS10800	COG3331	DNA recombination
IHV08_RS10825	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IHV08_RS10880	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
IHV08_RS10885	COG0756	dUTP diphosphatase activity
IHV08_RS10895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IHV08_RS10900	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IHV08_RS10905	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IHV08_RS10910	COG1780	Probably involved in ribonucleotide reductase function
IHV08_RS10995	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IHV08_RS11010	COG3584	3D domain protein
IHV08_RS11100	COG1395	domain, Protein
IHV08_RS11120	COG0776	regulation of translation
IHV08_RS11155	COG4373	Mu-like prophage FluMu protein gp28
IHV08_RS11245	COG0582	viral genome integration into host DNA
IHV08_RS11275	COG0741	lytic transglycosylase activity
IHV08_RS11275	COG0739	heme binding
IHV08_RS11275	COG1196	nuclear chromosome segregation
IHV08_RS11285	COG2433	Pfam Transposase IS66
IHV08_RS11310	COG5632	N-Acetylmuramoyl-L-alanine amidase
IHV08_RS11325	COG0457	Tetratricopeptide repeat
IHV08_RS11345	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IHV08_RS11375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IHV08_RS11395	COG5444	nuclease activity
IHV08_RS11400	COG4282	regulation of fungal-type cell wall biogenesis
IHV08_RS11415	COG1525	nuclease
IHV08_RS11430	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IHV08_RS11435	COG1086	Polysaccharide biosynthesis protein
IHV08_RS11440	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IHV08_RS11445	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IHV08_RS11450	COG1846	Transcriptional regulator
IHV08_RS11455	COG0534	Mate efflux family protein
IHV08_RS11465	COG4698	Protein conserved in bacteria
IHV08_RS11470	COG2755	lipolytic protein G-D-S-L family
IHV08_RS11475	COG1999	signal sequence binding
IHV08_RS11485	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IHV08_RS11490	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
IHV08_RS11495	COG1272	protein, Hemolysin III
IHV08_RS11500	COG0204	Acyl-transferase
IHV08_RS11505	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IHV08_RS11510	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IHV08_RS11515	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IHV08_RS11525	COG2136	Putative SAM-dependent methyltransferase
IHV08_RS11525	COG2521	methyltransferase
IHV08_RS11535	COG0129	dihydroxy-acid dehydratase activity
IHV08_RS11540	COG1413	lyase activity
IHV08_RS11545	COG1418	mRNA catabolic process
IHV08_RS11550	COG0386	Belongs to the glutathione peroxidase family
IHV08_RS11555	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
IHV08_RS11560	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IHV08_RS11570	COG1278	Cold shock
IHV08_RS11590	COG0328	RNA-DNA hybrid ribonuclease activity
IHV08_RS11595	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IHV08_RS11600	COG0328	RNA-DNA hybrid ribonuclease activity
IHV08_RS11610	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IHV08_RS11625	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
IHV08_RS11635	COG1755	Isoprenylcysteine carboxyl methyltransferase
IHV08_RS11640	COG3424	synthase
IHV08_RS11645	COG2233	PERMEase
IHV08_RS11650	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IHV08_RS11655	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IHV08_RS11665	COG0800	Aldolase
IHV08_RS11670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IHV08_RS11675	COG1609	Transcriptional regulator
IHV08_RS11680	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
IHV08_RS11685	COG1028	Short-chain dehydrogenase reductase Sdr
IHV08_RS11690	COG1199	ATP-dependent helicase activity
IHV08_RS11705	COG0116	Belongs to the methyltransferase superfamily
IHV08_RS11720	COG4474	Belongs to the UPF0398 family
IHV08_RS11735	COG3359	exonuclease
IHV08_RS11740	COG1205	dead DEAH box helicase
IHV08_RS11740	COG1111	helicase
IHV08_RS11745	COG2190	(PTS) system
IHV08_RS11750	COG0071	Belongs to the small heat shock protein (HSP20) family
IHV08_RS11785	COG3331	DNA recombination
IHV08_RS11790	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IHV08_RS11790	COG4499	WXG100 protein secretion system (Wss), protein YukC
IHV08_RS11800	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IHV08_RS11805	COG3935	DnaD domain protein
IHV08_RS11810	COG0017	Asparaginyl-tRNA synthetase
IHV08_RS11815	COG0436	Aminotransferase
IHV08_RS11820	COG5353	protein conserved in bacteria
IHV08_RS11830	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IHV08_RS11830	COG1199	ATP-dependent helicase activity
IHV08_RS11835	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
IHV08_RS11840	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IHV08_RS11845	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IHV08_RS11850	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
IHV08_RS11850	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
IHV08_RS11855	COG0617	tRNA 3'-terminal CCA addition
IHV08_RS11860	COG0438	transferase activity, transferring glycosyl groups
IHV08_RS11865	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IHV08_RS11870	COG1803	Methylglyoxal synthase
IHV08_RS11875	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IHV08_RS11880	COG1694	Mazg nucleotide pyrophosphohydrolase
IHV08_RS11885	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IHV08_RS11895	COG4347	Protein of unknown function (DUF1405)
IHV08_RS11900	COG2010	Cytochrome c
IHV08_RS11900	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IHV08_RS11905	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IHV08_RS11910	COG0723	plastoquinol--plastocyanin reductase activity
IHV08_RS11920	COG5582	Belongs to the UPF0302 family
IHV08_RS11925	COG0457	Tetratricopeptide repeat
IHV08_RS11930	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IHV08_RS11935	COG0287	Prephenate dehydrogenase
IHV08_RS11940	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IHV08_RS11945	COG0159	tryptophan synthase activity
IHV08_RS11950	COG0133	tryptophan synthase activity
IHV08_RS11955	COG0135	phosphoribosylanthranilate isomerase activity
IHV08_RS11965	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IHV08_RS11970	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IHV08_RS11975	COG4401	Chorismate mutase type I
IHV08_RS11980	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IHV08_RS11985	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IHV08_RS11990	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IHV08_RS11995	COG0105	UTP biosynthetic process
IHV08_RS12000	COG0142	geranyltranstransferase activity
IHV08_RS12005	COG2226	methyltransferase
IHV08_RS12010	COG0142	geranyltranstransferase activity
IHV08_RS12020	COG0302	gtp cyclohydrolase
IHV08_RS12025	COG0776	regulation of translation
IHV08_RS12030	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
IHV08_RS12045	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
IHV08_RS12050	COG1160	GTP binding
IHV08_RS12075	COG1304	FMN binding
IHV08_RS12080	COG0539	negative regulation of cytoplasmic translation
IHV08_RS12085	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IHV08_RS12095	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
IHV08_RS12100	COG2959	enzyme of heme biosynthesis
IHV08_RS12105	COG3773	Cell wall hydrolase
IHV08_RS12105	COG3409	Peptidoglycan-binding domain 1 protein
IHV08_RS12110	COG2339	peptidase activity
IHV08_RS12115	COG0492	ferredoxin-NADP+ reductase activity
IHV08_RS12120	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IHV08_RS12125	COG4862	establishment of competence for transformation
IHV08_RS12130	COG1408	metallophosphoesterase
IHV08_RS12140	COG1388	LysM domain
IHV08_RS12145	COG1266	CAAX protease self-immunity
IHV08_RS12150	COG0514	ATP-dependent DNA helicase (RecQ)
IHV08_RS12155	COG4955	Helix-turn-helix domain
IHV08_RS12160	COG1141	Ferredoxin
IHV08_RS12165	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IHV08_RS12170	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IHV08_RS12175	COG0710	3-dehydroquinate dehydratase activity
IHV08_RS12185	COG1595	DNA-templated transcription, initiation
IHV08_RS12190	COG5002	protein histidine kinase activity
IHV08_RS12195	COG0745	RESPONSE REGULATOR receiver
IHV08_RS12200	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IHV08_RS12205	COG1333	cytochrome c biogenesis protein
IHV08_RS12210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IHV08_RS12215	COG1187	pseudouridine synthase activity
IHV08_RS12220	COG0700	Nucleoside recognition
IHV08_RS12225	COG2715	membrane protein required for spore maturation
IHV08_RS12230	COG1686	Belongs to the peptidase S11 family
IHV08_RS12240	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IHV08_RS12245	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IHV08_RS12250	COG1547	Domain of unknown function (DUF309)
IHV08_RS12255	COG0456	acetyltransferase
IHV08_RS12260	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IHV08_RS12265	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IHV08_RS12265	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IHV08_RS12270	COG0307	riboflavin synthase, alpha
IHV08_RS12275	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IHV08_RS12275	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IHV08_RS12285	COG0681	Belongs to the peptidase S26 family
IHV08_RS12295	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
IHV08_RS12320	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IHV08_RS12325	COG4086	secreted protein
IHV08_RS12330	COG0019	diaminopimelate decarboxylase activity
IHV08_RS12335	COG0697	spore germination
IHV08_RS12350	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IHV08_RS12370	COG1191	sigma factor activity
IHV08_RS12375	COG2172	sigma factor antagonist activity
IHV08_RS12380	COG1366	Belongs to the anti-sigma-factor antagonist family
IHV08_RS12385	COG1686	Belongs to the peptidase S11 family
IHV08_RS12390	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IHV08_RS12395	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
IHV08_RS12400	COG4974	Belongs to the 'phage' integrase family
IHV08_RS12410	COG0735	belongs to the Fur family
IHV08_RS12415	COG1300	Membrane
IHV08_RS12425	COG0281	malic enzyme
IHV08_RS12430	COG1757	Na H antiporter
IHV08_RS12435	COG1027	Aspartate ammonia-lyase
IHV08_RS12440	COG0252	asparaginase activity
IHV08_RS12445	COG1396	sequence-specific DNA binding
IHV08_RS12450	COG1379	DNA repair
IHV08_RS12455	COG0494	nUDIX hydrolase
IHV08_RS12465	COG0667	Aldo Keto reductase
IHV08_RS12475	COG1073	alpha beta
IHV08_RS12485	COG4918	Iron-sulphur cluster biosynthesis
IHV08_RS12490	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IHV08_RS12490	COG0456	acetyltransferase
IHV08_RS12495	COG2329	Antibiotic biosynthesis monooxygenase
IHV08_RS12500	COG0456	acetyltransferase
IHV08_RS12510	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IHV08_RS12520	COG2211	Major facilitator Superfamily
IHV08_RS12530	COG0346	lactoylglutathione lyase activity
IHV08_RS12535	COG1072	(Pantothenic acid kinase))
IHV08_RS12540	COG3048	D-serine ammonia-lyase activity
IHV08_RS12545	COG0300	oxidoreductase activity
IHV08_RS12550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IHV08_RS12555	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IHV08_RS12560	COG4187	Peptidase family M20/M25/M40
IHV08_RS12565	COG1902	pentaerythritol trinitrate reductase activity
IHV08_RS12570	COG0596	Alpha beta hydrolase
IHV08_RS12580	COG1234	tRNA 3'-trailer cleavage
IHV08_RS12585	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IHV08_RS12590	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IHV08_RS12595	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IHV08_RS12605	COG0706	membrane insertase activity
IHV08_RS12610	COG3361	conserved protein (COG2071)
IHV08_RS12615	COG2195	Cleaves the N-terminal amino acid of tripeptides
IHV08_RS12620	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IHV08_RS12625	COG0346	lactoylglutathione lyase activity
IHV08_RS12635	COG1376	ErfK ybiS ycfS ynhG family protein
IHV08_RS12640	COG4129	membrane
IHV08_RS12645	COG1126	abc transporter atp-binding protein
IHV08_RS12650	COG0765	amino acid transport
IHV08_RS12655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IHV08_RS12665	COG1597	lipid kinase activity
IHV08_RS12670	COG2814	Major facilitator Superfamily
IHV08_RS12675	COG0789	Transcriptional regulator
IHV08_RS12675	COG4978	Transcriptional regulator
IHV08_RS12680	COG0508	dehydrogenase complex catalyzes the overall conversion of
IHV08_RS12685	COG0022	dehydrogenase e1 component
IHV08_RS12690	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IHV08_RS12695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IHV08_RS12700	COG3426	butyrate kinase activity
IHV08_RS12705	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IHV08_RS12710	COG0280	phosphate acetyltransferase
IHV08_RS12715	COG3290	protein histidine kinase activity
IHV08_RS12715	COG3829	transcription factor binding
IHV08_RS12725	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IHV08_RS12730	COG2079	MmgE PrpD family protein
IHV08_RS12735	COG0372	Belongs to the citrate synthase family
IHV08_RS12740	COG1960	acyl-CoA dehydrogenase activity
IHV08_RS12745	COG1250	3-hydroxyacyl-CoA dehydrogenase
IHV08_RS12750	COG0183	Belongs to the thiolase family
IHV08_RS12755	COG0584	glycerophosphoryl diester phosphodiesterase
IHV08_RS12760	COG0860	N-Acetylmuramoyl-L-alanine amidase
IHV08_RS12775	COG1902	pentaerythritol trinitrate reductase activity
IHV08_RS12780	COG0745	RESPONSE REGULATOR receiver
IHV08_RS12785	COG0750	zinc metalloprotease
IHV08_RS12790	COG0497	DNA recombination
IHV08_RS12795	COG1438	arginine binding
IHV08_RS12800	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
IHV08_RS12805	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IHV08_RS12810	COG0142	geranyltranstransferase activity
IHV08_RS12815	COG1722	exodeoxyribonuclease VII activity
IHV08_RS12820	COG1570	exodeoxyribonuclease VII activity
IHV08_RS12825	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IHV08_RS12830	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IHV08_RS12835	COG1302	Protein conserved in bacteria
IHV08_RS12840	COG0439	Biotin carboxylase
IHV08_RS12845	COG0511	ligase activity, forming carbon-carbon bonds
IHV08_RS12885	COG3854	ATPases associated with a variety of cellular activities
IHV08_RS12895	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IHV08_RS12900	COG0006	proline dipeptidase activity
IHV08_RS12905	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IHV08_RS12915	COG3872	metal-dependent enzyme
IHV08_RS12925	COG1752	Esterase of the alpha-beta hydrolase superfamily
IHV08_RS12930	COG1321	iron dependent repressor
IHV08_RS12935	COG0095	Lipoate-protein ligase
IHV08_RS12940	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IHV08_RS12945	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IHV08_RS12950	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IHV08_RS12955	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IHV08_RS12960	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IHV08_RS12975	COG1396	sequence-specific DNA binding
IHV08_RS12985	COG0681	Belongs to the peptidase S26 family
IHV08_RS13010	COG4940	Competence protein ComGF
IHV08_RS13020	COG4970	Tfp pilus assembly protein FimT
IHV08_RS13025	COG4537	Required for transformation and DNA binding
IHV08_RS13030	COG1459	type II secretion system
IHV08_RS13035	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IHV08_RS13040	COG0598	Magnesium transport protein CorA
IHV08_RS13045	COG1253	flavin adenine dinucleotide binding
IHV08_RS13050	COG1366	Belongs to the anti-sigma-factor antagonist family
IHV08_RS13060	COG1393	Belongs to the ArsC family
IHV08_RS13070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IHV08_RS13080	COG0011	TIGRFAM Protein of
IHV08_RS13090	COG2866	Carboxypeptidase
IHV08_RS13095	COG1368	sulfuric ester hydrolase activity
IHV08_RS13100	COG1940	carbohydrate kinase activity
IHV08_RS13105	COG4483	Protein conserved in bacteria
IHV08_RS13110	COG0705	Rhomboid family
IHV08_RS13110	COG0457	Tetratricopeptide repeat
IHV08_RS13120	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IHV08_RS13130	COG0438	transferase activity, transferring glycosyl groups
IHV08_RS13145	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IHV08_RS13150	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IHV08_RS13155	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IHV08_RS13160	COG0581	inorganic phosphate transmembrane transporter activity
IHV08_RS13165	COG0573	inorganic phosphate transmembrane transporter activity
IHV08_RS13170	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IHV08_RS13175	COG0768	penicillin binding
IHV08_RS13180	COG0477	Major facilitator Superfamily
IHV08_RS13185	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IHV08_RS13190	COG2839	Protein conserved in bacteria
IHV08_RS13195	COG5521	maltodextrose utilization protein MalA
IHV08_RS13200	COG1388	LysM domain
IHV08_RS13205	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IHV08_RS13210	COG4709	membrane
IHV08_RS13215	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
IHV08_RS13220	COG0735	belongs to the Fur family
IHV08_RS13225	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IHV08_RS13235	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IHV08_RS13240	COG0513	Belongs to the DEAD box helicase family
IHV08_RS13250	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IHV08_RS13255	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IHV08_RS13260	COG2384	SAM-dependent methyltransferase
IHV08_RS13265	COG2010	Cytochrome c
IHV08_RS13270	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IHV08_RS13275	COG0358	DNA primase activity
IHV08_RS13280	COG1671	Belongs to the UPF0178 family
IHV08_RS13285	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
IHV08_RS13290	COG0517	IMP dehydrogenase activity
IHV08_RS13295	COG0751	glycine-tRNA ligase activity
IHV08_RS13300	COG0752	glycyl-tRNA synthetase alpha subunit
IHV08_RS13305	COG1381	Involved in DNA repair and RecF pathway recombination
IHV08_RS13315	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IHV08_RS13320	COG0295	cytidine deaminase activity
IHV08_RS13325	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IHV08_RS13330	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IHV08_RS13335	COG1480	7TM receptor with intracellular HD hydrolase
IHV08_RS13340	COG1702	phosphate starvation-inducible protein PhoH
IHV08_RS13345	COG0561	phosphatase activity
IHV08_RS13360	COG4864	UPF0365 protein
IHV08_RS13365	COG1030	water channel activity
IHV08_RS13370	COG1610	YqeY-like protein
IHV08_RS13380	COG1283	sodium-dependent phosphate transmembrane transporter activity
IHV08_RS13385	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IHV08_RS13390	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IHV08_RS13395	COG2264	protein methyltransferase activity
IHV08_RS13400	COG0484	heat shock protein binding
IHV08_RS13405	COG0443	Heat shock 70 kDa protein
IHV08_RS13410	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IHV08_RS13415	COG1420	regulation of RNA biosynthetic process
IHV08_RS13420	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IHV08_RS13425	COG0481	GTPase activity
IHV08_RS13435	COG0860	N-Acetylmuramoyl-L-alanine amidase
IHV08_RS13440	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IHV08_RS13445	COG0268	Binds directly to 16S ribosomal RNA
IHV08_RS13450	COG1466	dna polymerase III delta subunit
IHV08_RS13465	COG0658	competence protein
IHV08_RS13465	COG2333	competence protein COMEC
IHV08_RS13470	COG2131	deaminase
IHV08_RS13475	COG1596	polysaccharide export
IHV08_RS13475	COG1555	photosystem II stabilization
IHV08_RS13480	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IHV08_RS13485	COG2226	methyltransferase
IHV08_RS13490	COG0799	negative regulation of ribosome biogenesis
IHV08_RS13495	COG1713	HD superfamily hydrolase involved in NAD metabolism
IHV08_RS13500	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IHV08_RS13505	COG1534	Rna-binding protein
IHV08_RS13510	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IHV08_RS13515	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IHV08_RS13520	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
IHV08_RS13530	COG2755	lipolytic protein G-D-S-L family
IHV08_RS13535	COG3409	Peptidoglycan-binding domain 1 protein
IHV08_RS13535	COG5632	N-Acetylmuramoyl-L-alanine amidase
IHV08_RS13540	COG0398	Pfam SNARE associated Golgi protein
IHV08_RS13545	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
IHV08_RS13555	COG3209	COG3209 Rhs family protein
IHV08_RS13565	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IHV08_RS13580	COG1802	Transcriptional regulator
IHV08_RS13585	COG0473	3-isopropylmalate dehydrogenase activity
IHV08_RS13585	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IHV08_RS13590	COG0473	3-isopropylmalate dehydrogenase activity
IHV08_RS13590	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IHV08_RS13595	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IHV08_RS13605	COG4124	Belongs to the glycosyl hydrolase 26 family
IHV08_RS13610	COG0457	Tetratricopeptide repeat
IHV08_RS13625	COG5444	nuclease activity
IHV08_RS13655	COG5484	DNA packaging
IHV08_RS13720	COG0563	adenylate kinase activity
IHV08_RS13725	COG2856	Zn peptidase
IHV08_RS13745	COG4124	Belongs to the glycosyl hydrolase 26 family
IHV08_RS13750	COG0730	response to heat
IHV08_RS13755	COG0425	Belongs to the sulfur carrier protein TusA family
IHV08_RS13760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IHV08_RS13760	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IHV08_RS13770	COG0425	Belongs to the sulfur carrier protein TusA family
IHV08_RS13770	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IHV08_RS13775	COG2210	Belongs to the sulfur carrier protein TusA family
IHV08_RS13780	COG1937	Protein conserved in bacteria
IHV08_RS13785	COG0662	Cupin 2, conserved barrel domain protein
IHV08_RS13800	COG0789	Transcriptional regulator
IHV08_RS13800	COG4978	Transcriptional regulator
IHV08_RS13805	COG2814	Major facilitator Superfamily
IHV08_RS13810	COG0456	acetyltransferase
IHV08_RS13815	COG1253	flavin adenine dinucleotide binding
IHV08_RS13825	COG0697	spore germination
IHV08_RS13830	COG0583	DNA-binding transcription factor activity
IHV08_RS13835	COG2072	flavoprotein involved in K transport
IHV08_RS13840	COG1230	cation diffusion facilitator family transporter
IHV08_RS13845	COG1942	4-Oxalocrotonate Tautomerase
IHV08_RS13850	COG0583	DNA-binding transcription factor activity
IHV08_RS13860	COG1114	Component of the transport system for branched-chain amino acids
IHV08_RS13865	COG1687	branched-chain amino acid
IHV08_RS13870	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IHV08_RS13875	COG1522	sequence-specific DNA binding
IHV08_RS13885	COG2124	cytochrome p450
IHV08_RS13895	COG1335	isochorismatase
IHV08_RS13915	COG2318	DinB family
IHV08_RS13925	COG2070	2-Nitropropane dioxygenase
IHV08_RS13930	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IHV08_RS13950	COG3443	Belongs to the bacterial solute-binding protein 9 family
IHV08_RS13955	COG1595	DNA-templated transcription, initiation
IHV08_RS13960	COG0667	Aldo Keto reductase
IHV08_RS13965	COG2851	Citrate transporter
IHV08_RS13970	COG0583	DNA-binding transcription factor activity
IHV08_RS13975	COG2828	Protein conserved in bacteria
IHV08_RS13980	COG3409	Peptidoglycan-binding domain 1 protein
IHV08_RS13985	COG5566	PFAM Mor transcription activator
IHV08_RS13990	COG0596	Alpha beta hydrolase
IHV08_RS13995	COG4991	sh3 domain protein
IHV08_RS14000	COG4991	sh3 domain protein
IHV08_RS14010	COG0346	lactoylglutathione lyase activity
IHV08_RS14020	COG5577	PFAM Coat F domain
IHV08_RS14025	COG1063	alcohol dehydrogenase
IHV08_RS14035	COG5577	PFAM Coat F domain
IHV08_RS14040	COG0789	Transcriptional regulator
IHV08_RS14050	COG1064	alcohol dehydrogenase
IHV08_RS14055	COG0693	protein deglycase activity
IHV08_RS14060	COG1621	beta-fructofuranosidase activity
IHV08_RS14065	COG3716	PTS system mannose fructose sorbose family IID component
IHV08_RS14070	COG3715	PTS system
IHV08_RS14075	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IHV08_RS14080	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
IHV08_RS14085	COG3933	PFAM sigma-54 factor interaction domain-containing protein
IHV08_RS14085	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
IHV08_RS14095	COG1113	amino acid transport
IHV08_RS14100	COG1280	lysine exporter protein (LysE YggA)
IHV08_RS14105	COG1378	Sugar-specific transcriptional regulator TrmB
IHV08_RS14110	COG1595	DNA-templated transcription, initiation
IHV08_RS14120	COG2755	lipolytic protein G-D-S-L family
IHV08_RS14120	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IHV08_RS14130	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IHV08_RS14130	COG2124	cytochrome p450
IHV08_RS14135	COG1309	transcriptional regulator
IHV08_RS14140	COG2226	methyltransferase
IHV08_RS14155	COG2116	formate transmembrane transporter activity
IHV08_RS14160	COG5609	conserved protein (DUF2294)
IHV08_RS14165	COG3383	formate dehydrogenase (NAD+) activity
IHV08_RS14170	COG2427	Protein of unknown function (DUF1641)
IHV08_RS14180	COG0626	cystathionine gamma-synthase activity
IHV08_RS14185	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IHV08_RS14190	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IHV08_RS14195	COG2226	methyltransferase
IHV08_RS14210	COG0768	penicillin binding
IHV08_RS14215	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IHV08_RS14220	COG0572	uridine kinase
IHV08_RS14225	COG0826	peptidase U32
IHV08_RS14230	COG0826	peptidase U32
IHV08_RS14235	COG4122	O-methyltransferase activity
IHV08_RS14240	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IHV08_RS14245	COG3906	Belongs to the UPF0473 family
IHV08_RS14250	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IHV08_RS14255	COG4472	Bacterial protein of unknown function (DUF965)
IHV08_RS14260	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IHV08_RS14265	COG0628	permease
IHV08_RS14270	COG1126	abc transporter atp-binding protein
IHV08_RS14275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IHV08_RS14280	COG0765	amino acid transport
IHV08_RS14285	COG0765	amino acid transport
IHV08_RS14300	COG3881	PFAM PRC-barrel domain
IHV08_RS14305	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IHV08_RS14310	COG0457	Tetratricopeptide repeat
IHV08_RS14315	COG0482	sulfurtransferase activity
IHV08_RS14320	COG1104	cysteine desulfurase activity
IHV08_RS14325	COG1959	2 iron, 2 sulfur cluster binding
IHV08_RS14330	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IHV08_RS14335	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IHV08_RS14345	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IHV08_RS14350	COG0124	histidyl-tRNA synthetase
IHV08_RS14360	COG4991	sh3 domain protein
IHV08_RS14360	COG3103	Sh3 type 3 domain protein
IHV08_RS14360	COG0860	N-Acetylmuramoyl-L-alanine amidase
IHV08_RS14365	COG1490	D-aminoacyl-tRNA deacylase activity
IHV08_RS14370	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IHV08_RS14375	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IHV08_RS14380	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
IHV08_RS14380	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IHV08_RS14385	COG5416	Lipopolysaccharide assembly protein A domain
IHV08_RS14390	COG0490	domain, Protein
IHV08_RS14395	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IHV08_RS14395	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IHV08_RS14405	COG2244	polysaccharide biosynthetic process
IHV08_RS14410	COG2323	membrane
IHV08_RS14420	COG1862	Preprotein translocase
IHV08_RS14425	COG0343	queuine tRNA-ribosyltransferase activity
IHV08_RS14430	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IHV08_RS14440	COG2255	four-way junction helicase activity
IHV08_RS14445	COG0632	four-way junction helicase activity
IHV08_RS14455	COG2814	Major facilitator Superfamily
IHV08_RS14460	COG0673	inositol 2-dehydrogenase activity
IHV08_RS14465	COG2112	serine threonine protein kinase
IHV08_RS14485	COG1115	amino acid carrier protein
IHV08_RS14490	COG0217	transcriptional regulatory protein
IHV08_RS14500	COG1388	LysM domain
IHV08_RS14505	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IHV08_RS14510	COG0157	Belongs to the NadC ModD family
IHV08_RS14515	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IHV08_RS14520	COG1104	cysteine desulfurase activity
IHV08_RS14525	COG1827	regulation of RNA biosynthetic process
IHV08_RS14530	COG0077	Prephenate dehydratase
IHV08_RS14535	COG4492	Belongs to the UPF0735 family
IHV08_RS14540	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IHV08_RS14545	COG3290	protein histidine kinase activity
IHV08_RS14555	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IHV08_RS14560	COG2868	ribosomal protein
IHV08_RS14565	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IHV08_RS14570	COG1994	Peptidase M50
IHV08_RS14575	COG0739	heme binding
IHV08_RS14580	COG2894	cell division
IHV08_RS14585	COG0850	regulation of cytokinetic process
IHV08_RS14590	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IHV08_RS14600	COG1077	Cell shape determining protein MreB Mrl
IHV08_RS14605	COG2003	Belongs to the UPF0758 family
IHV08_RS14610	COG0424	maF-like protein
IHV08_RS14620	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
IHV08_RS14625	COG0285	dihydrofolate synthase activity
IHV08_RS14630	COG0525	valine-tRNA ligase activity
IHV08_RS14640	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IHV08_RS14645	COG1388	LysM domain
IHV08_RS14650	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IHV08_RS14655	COG0113	porphobilinogen synthase activity
IHV08_RS14660	COG1587	Uroporphyrinogen-III synthase
IHV08_RS14665	COG0181	hydroxymethylbilane synthase activity
IHV08_RS14670	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IHV08_RS14675	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IHV08_RS14685	COG0218	Necessary for normal cell division and for the maintenance of normal septation
IHV08_RS14690	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IHV08_RS14695	COG0470	DNA polymerase III
IHV08_RS14695	COG1067	ATP-dependent peptidase activity
IHV08_RS14700	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IHV08_RS14705	COG0544	peptidyl-prolyl cis-trans isomerase activity
IHV08_RS14710	COG1477	protein flavinylation
IHV08_RS14710	COG0457	Tetratricopeptide repeat
IHV08_RS14715	COG0066	3-isopropylmalate dehydratase activity
IHV08_RS14720	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IHV08_RS14725	COG0473	3-isopropylmalate dehydrogenase activity
IHV08_RS14730	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IHV08_RS14735	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IHV08_RS14740	COG0440	acetolactate synthase activity
IHV08_RS14745	COG0028	Belongs to the TPP enzyme family
IHV08_RS14755	COG0454	-acetyltransferase
IHV08_RS14765	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
IHV08_RS14775	COG0622	Phosphoesterase
IHV08_RS14780	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IHV08_RS14785	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IHV08_RS14790	COG5401	PFAM Sporulation and spore germination
IHV08_RS14795	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IHV08_RS14800	COG1846	Transcriptional regulator
IHV08_RS14805	COG2197	response regulator
IHV08_RS14810	COG0824	Thioesterase
IHV08_RS14815	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IHV08_RS14820	COG1053	succinate dehydrogenase
IHV08_RS14825	COG2009	succinate dehydrogenase
IHV08_RS14830	COG1719	4-vinyl reductase, 4VR
IHV08_RS14835	COG0527	aspartate kinase activity
IHV08_RS14840	COG0322	excinuclease ABC activity
IHV08_RS14845	COG3118	belongs to the thioredoxin family
IHV08_RS14850	COG3534	alpha-L-arabinofuranosidase
IHV08_RS14855	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
IHV08_RS14860	COG2086	electron transfer activity
IHV08_RS14865	COG1024	Enoyl-CoA hydratase
IHV08_RS14870	COG1309	transcriptional regulator
IHV08_RS14875	COG0318	PFAM AMP-dependent synthetase and ligase
IHV08_RS14880	COG3766	membrane
IHV08_RS14885	COG1193	negative regulation of DNA recombination
IHV08_RS14890	COG1796	DNA polymerase
IHV08_RS14890	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
IHV08_RS14895	COG1286	toxin biosynthetic process
IHV08_RS14900	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IHV08_RS14905	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IHV08_RS14910	COG0072	phenylalanine-tRNA ligase activity
IHV08_RS14910	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IHV08_RS14915	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IHV08_RS14925	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IHV08_RS14935	COG3835	regulator
IHV08_RS14940	COG0277	FAD linked oxidase domain protein
IHV08_RS14945	COG0247	lactate metabolic process
IHV08_RS14950	COG0346	lactoylglutathione lyase activity
IHV08_RS14955	COG1966	Carbon starvation protein
IHV08_RS14960	COG3534	alpha-L-arabinofuranosidase
IHV08_RS14965	COG0395	ABC-type sugar transport system, permease component
IHV08_RS14970	COG1175	transmembrane transport
IHV08_RS14975	COG1653	transport
IHV08_RS14980	COG0371	Dehydrogenase
IHV08_RS14985	COG0647	UMP catabolic process
IHV08_RS14990	COG0235	Class ii aldolase
IHV08_RS14995	COG1069	ribulokinase activity
IHV08_RS15000	COG2160	L-arabinose isomerase activity
IHV08_RS15005	COG3507	Belongs to the glycosyl hydrolase 43 family
IHV08_RS15010	COG1363	Peptidase, m42
IHV08_RS15020	COG3326	Membrane
IHV08_RS15025	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IHV08_RS15030	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IHV08_RS15035	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IHV08_RS15045	COG1346	cytolysis
IHV08_RS15050	COG1380	Effector of murein hydrolase LrgA
IHV08_RS15055	COG3279	Response regulator of the LytR AlgR family
IHV08_RS15060	COG3275	phosphorelay sensor kinase activity
IHV08_RS15065	COG1011	Hydrolase
IHV08_RS15070	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IHV08_RS15080	COG0398	Pfam SNARE associated Golgi protein
IHV08_RS15085	COG1484	DNA-dependent DNA replication
IHV08_RS15090	COG3611	Membrane attachment protein
IHV08_RS15095	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IHV08_RS15100	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
IHV08_RS15105	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IHV08_RS15110	COG1733	regulation of RNA biosynthetic process
IHV08_RS15115	COG2814	Major facilitator Superfamily
IHV08_RS15120	COG0656	L-ascorbic acid biosynthetic process
IHV08_RS15125	COG0237	dephospho-CoA kinase activity
IHV08_RS15130	COG1971	Probably functions as a manganese efflux pump
IHV08_RS15135	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IHV08_RS15140	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IHV08_RS15140	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IHV08_RS15145	COG5002	protein histidine kinase activity
IHV08_RS15150	COG0745	RESPONSE REGULATOR receiver
IHV08_RS15155	COG0039	L-malate dehydrogenase activity
IHV08_RS15160	COG0538	isocitrate dehydrogenase activity
IHV08_RS15165	COG0372	Belongs to the citrate synthase family
IHV08_RS15170	COG2707	UPF0756 membrane protein
IHV08_RS15175	COG0628	permease
IHV08_RS15180	COG3030	protein affecting phage T7 exclusion by the F plasmid
IHV08_RS15185	COG0469	pyruvate kinase activity
IHV08_RS15190	COG0205	6-phosphofructokinase activity
IHV08_RS15195	COG0825	malonyl-CoA metabolic process
IHV08_RS15200	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IHV08_RS15205	COG0281	malic enzyme
IHV08_RS15210	COG0587	DNA-directed DNA polymerase activity
IHV08_RS15230	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IHV08_RS15240	COG4109	DRTGG domain
IHV08_RS15245	COG0730	response to heat
IHV08_RS15250	COG1473	amidohydrolase
IHV08_RS15255	COG0196	riboflavin kinase activity
IHV08_RS15260	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IHV08_RS15265	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IHV08_RS15270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IHV08_RS15275	COG1126	abc transporter atp-binding protein
IHV08_RS15280	COG0765	amino acid transport
IHV08_RS15285	COG0765	amino acid transport
IHV08_RS15290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IHV08_RS15295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IHV08_RS15300	COG0454	-acetyltransferase
IHV08_RS15305	COG0583	DNA-binding transcription factor activity
IHV08_RS15310	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IHV08_RS15315	COG1028	Short-chain dehydrogenase reductase Sdr
IHV08_RS15320	COG0165	Argininosuccinate lyase
IHV08_RS15325	COG0137	argininosuccinate synthase activity
IHV08_RS15330	COG0521	Mo-molybdopterin cofactor biosynthetic process
IHV08_RS15335	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IHV08_RS15345	COG0827	DNA restriction-modification system
IHV08_RS15350	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IHV08_RS15355	COG3874	Sporulation protein YtfJ
IHV08_RS15365	COG1714	RDD family
IHV08_RS15370	COG0616	signal peptide processing
IHV08_RS15375	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IHV08_RS15380	COG1574	metal-dependent hydrolase with the TIM-barrel fold
IHV08_RS15385	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IHV08_RS15395	COG0301	tRNA thio-modification
IHV08_RS15400	COG1104	cysteine desulfurase activity
IHV08_RS15405	COG1114	Component of the transport system for branched-chain amino acids
IHV08_RS15410	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IHV08_RS15415	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
IHV08_RS15420	COG1309	transcriptional regulator
IHV08_RS15425	COG1956	GAF domain-containing protein
IHV08_RS15430	COG2203	Gaf domain
IHV08_RS15430	COG2199	diguanylate cyclase activity
IHV08_RS15435	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IHV08_RS15440	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IHV08_RS15445	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IHV08_RS15450	COG0454	-acetyltransferase
IHV08_RS15455	COG0517	IMP dehydrogenase activity
IHV08_RS15460	COG0123	including yeast histone deacetylase and acetoin utilization protein
IHV08_RS15465	COG1360	Flagellar Motor Protein
IHV08_RS15470	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IHV08_RS15475	COG1609	Transcriptional regulator
IHV08_RS15480	COG1605	Chorismate mutase
IHV08_RS15480	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
IHV08_RS15485	COG3118	belongs to the thioredoxin family
IHV08_RS15490	COG4980	gas vesicle protein
IHV08_RS15495	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IHV08_RS15500	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IHV08_RS15505	COG1674	ftsk spoiiie
IHV08_RS15510	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IHV08_RS15515	COG4848	Belongs to the UPF0354 family
IHV08_RS15520	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IHV08_RS15535	COG1363	Peptidase, m42
IHV08_RS15540	COG5584	Small secreted protein
IHV08_RS15545	COG0281	malic enzyme
IHV08_RS15550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IHV08_RS15555	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IHV08_RS15565	COG0510	thiamine kinase activity
IHV08_RS15570	COG1523	belongs to the glycosyl hydrolase 13 family
IHV08_RS15575	COG1597	lipid kinase activity
IHV08_RS15585	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IHV08_RS15590	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IHV08_RS15595	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IHV08_RS15600	COG2252	PERMEase
IHV08_RS15605	COG4473	ABC transporter
IHV08_RS15610	COG1131	(ABC) transporter
IHV08_RS15615	COG1349	DNA-binding transcription factor activity
IHV08_RS15620	COG1187	pseudouridine synthase activity
IHV08_RS15625	COG2244	polysaccharide biosynthetic process
IHV08_RS15630	COG2081	HI0933 family
IHV08_RS15635	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IHV08_RS15645	COG5578	integral membrane protein
IHV08_RS15650	COG0673	inositol 2-dehydrogenase activity
IHV08_RS15655	COG1653	transport
IHV08_RS15660	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
IHV08_RS15665	COG4209	transmembrane transport
IHV08_RS15670	COG2207	Transcriptional regulator
IHV08_RS15675	COG1653	transport
IHV08_RS15680	COG0395	ABC-type sugar transport system, permease component
IHV08_RS15685	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IHV08_RS15690	COG2124	cytochrome p450
IHV08_RS15695	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IHV08_RS15705	COG0156	8-amino-7-oxononanoate synthase activity
IHV08_RS15710	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IHV08_RS15715	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
IHV08_RS15720	COG1073	alpha beta
IHV08_RS15725	COG1609	Transcriptional regulator
IHV08_RS15730	COG1653	transport
IHV08_RS15735	COG1175	transmembrane transport
IHV08_RS15740	COG0395	ABC-type sugar transport system, permease component
IHV08_RS15745	COG1486	melibiose metabolic process
IHV08_RS15750	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IHV08_RS15755	COG0495	leucyl-tRNA aminoacylation
IHV08_RS15765	COG1366	Belongs to the anti-sigma-factor antagonist family
IHV08_RS15765	COG2202	Pas domain
IHV08_RS15770	COG2814	Major facilitator Superfamily
IHV08_RS15775	COG2433	Pfam Transposase IS66
IHV08_RS15780	COG0577	efflux transmembrane transporter activity
IHV08_RS15785	COG1136	(ABC) transporter
IHV08_RS15790	COG2205	protein histidine kinase activity
IHV08_RS15795	COG0745	RESPONSE REGULATOR receiver
IHV08_RS15800	COG0577	efflux transmembrane transporter activity
IHV08_RS15805	COG1136	(ABC) transporter
IHV08_RS15820	COG1131	(ABC) transporter
IHV08_RS15825	COG1725	Transcriptional regulator
IHV08_RS15840	COG1242	4 iron, 4 sulfur cluster binding
IHV08_RS15845	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
IHV08_RS15855	COG2267	carboxylic ester hydrolase activity
IHV08_RS15860	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IHV08_RS15865	COG1113	amino acid transport
IHV08_RS15870	COG0367	asparagine synthase
IHV08_RS15875	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IHV08_RS15880	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IHV08_RS15890	COG1506	peptidase
IHV08_RS15895	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IHV08_RS15900	COG1116	anion transmembrane transporter activity
IHV08_RS15905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IHV08_RS15910	COG0494	nUDIX hydrolase
IHV08_RS15915	COG4824	toxin secretion phage lysis holin
IHV08_RS15920	COG0783	Belongs to the Dps family
IHV08_RS15935	COG1854	S-ribosylhomocysteine lyase activity
IHV08_RS15940	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
IHV08_RS15945	COG0288	reversible hydration of carbon dioxide
IHV08_RS15950	COG0254	rRNA binding
IHV08_RS15955	COG1271	oxidase subunit
IHV08_RS15960	COG1294	oxidase, subunit
IHV08_RS15970	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IHV08_RS15975	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IHV08_RS15975	COG1321	iron dependent repressor
IHV08_RS15980	COG1121	(ABC) transporter
IHV08_RS15985	COG0803	Belongs to the bacterial solute-binding protein 9 family
IHV08_RS15990	COG4948	Mandelate Racemase Muconate Lactonizing
IHV08_RS15995	COG0318	PFAM AMP-dependent synthetase and ligase
IHV08_RS16000	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IHV08_RS16005	COG0596	Alpha beta hydrolase
IHV08_RS16010	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IHV08_RS16015	COG1169	isochorismate synthase
IHV08_RS16020	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IHV08_RS16025	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IHV08_RS16030	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IHV08_RS16035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IHV08_RS16040	COG0438	transferase activity, transferring glycosyl groups
IHV08_RS16050	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IHV08_RS16055	COG0438	transferase activity, transferring glycosyl groups
IHV08_RS16060	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IHV08_RS16065	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
IHV08_RS16070	COG0058	SHG alpha-glucan phosphorylase activity
IHV08_RS16075	COG0297	glycogen (starch) synthase activity
IHV08_RS16080	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IHV08_RS16085	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IHV08_RS16090	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IHV08_RS16215	COG3859	Proton-coupled thiamine transporter YuaJ
IHV08_RS16220	COG1247	-acetyltransferase
IHV08_RS16225	COG2268	Band 7 protein
IHV08_RS16230	COG1585	Membrane protein implicated in regulation of membrane protease activity
IHV08_RS16235	COG2318	DinB family
IHV08_RS16245	COG1454	alcohol dehydrogenase
IHV08_RS16250	COG1012	belongs to the aldehyde dehydrogenase family
IHV08_RS16255	COG1510	regulation of RNA biosynthetic process
IHV08_RS16265	COG0569	domain protein
IHV08_RS16270	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IHV08_RS16275	COG4682	membrane
IHV08_RS16280	COG1705	Flagellar rod assembly protein muramidase FlgJ
IHV08_RS16285	COG0477	Major facilitator Superfamily
IHV08_RS16290	COG5553	Cysteine dioxygenase type I
IHV08_RS16300	COG1968	undecaprenyl-diphosphatase activity
IHV08_RS16305	COG0628	permease
IHV08_RS16310	COG0673	inositol 2-dehydrogenase activity
IHV08_RS16315	COG4806	L-rhamnose isomerase
IHV08_RS16320	COG3254	rhamnose metabolic process
IHV08_RS16325	COG1070	Carbohydrate kinase
IHV08_RS16330	COG1349	DNA-binding transcription factor activity
IHV08_RS16335	COG1028	Short-chain dehydrogenase reductase Sdr
IHV08_RS16335	COG3347	Dehydrogenase
IHV08_RS16340	COG0840	transmembrane signaling receptor activity
IHV08_RS16345	COG0840	transmembrane signaling receptor activity
IHV08_RS16350	COG0840	transmembrane signaling receptor activity
IHV08_RS16355	COG0840	transmembrane signaling receptor activity
IHV08_RS16370	COG0432	Pfam Uncharacterised protein family UPF0047
IHV08_RS16380	COG0366	Alpha amylase catalytic
IHV08_RS16385	COG1253	flavin adenine dinucleotide binding
IHV08_RS16390	COG2738	Putative neutral zinc metallopeptidase
IHV08_RS16405	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IHV08_RS16420	COG0166	Belongs to the GPI family
IHV08_RS16425	COG1979	alcohol dehydrogenase
IHV08_RS16430	COG1979	alcohol dehydrogenase
IHV08_RS16435	COG2155	Conserved Protein
IHV08_RS16440	COG1098	S1 RNA binding domain
IHV08_RS16445	COG0436	Aminotransferase
IHV08_RS16450	COG1522	sequence-specific DNA binding
IHV08_RS16455	COG2267	carboxylic ester hydrolase activity
IHV08_RS16465	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
IHV08_RS16470	COG2205	protein histidine kinase activity
IHV08_RS16480	COG5018	Exonuclease
IHV08_RS16485	COG2814	Major facilitator Superfamily
IHV08_RS16490	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IHV08_RS16495	COG3011	Protein conserved in bacteria
IHV08_RS16505	COG3290	protein histidine kinase activity
IHV08_RS16510	COG4565	transcriptional regulatory protein
IHV08_RS16515	COG1744	ABC transporter substrate-binding protein PnrA-like
IHV08_RS16520	COG3845	ABC transporter
IHV08_RS16525	COG4603	Belongs to the binding-protein-dependent transport system permease family
IHV08_RS16530	COG1079	Belongs to the binding-protein-dependent transport system permease family
IHV08_RS16535	COG3493	citrate carrier protein
IHV08_RS16545	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IHV08_RS16545	COG2111	Na H antiporter
IHV08_RS16550	COG2111	Na H antiporter
IHV08_RS16555	COG1006	Multisubunit Na H antiporter MnhC subunit
IHV08_RS16560	COG0651	ATP synthesis coupled electron transport
IHV08_RS16565	COG1863	multisubunit Na H antiporter MnhE subunit
IHV08_RS16570	COG2212	antiporter activity
IHV08_RS16575	COG1320	monovalent cation:proton antiporter activity
IHV08_RS16580	COG2050	protein possibly involved in aromatic compounds catabolism
IHV08_RS16585	COG2197	response regulator
IHV08_RS16590	COG4585	Histidine kinase
IHV08_RS16600	COG0142	geranyltranstransferase activity
IHV08_RS16615	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
IHV08_RS16620	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IHV08_RS16625	COG1335	isochorismatase
IHV08_RS16630	COG5506	Protein of unknown function (DUF1694)
IHV08_RS16645	COG0628	permease
IHV08_RS16660	COG1418	mRNA catabolic process
IHV08_RS16665	COG1028	Short-chain dehydrogenase reductase Sdr
IHV08_RS16675	COG1511	domain protein
IHV08_RS16680	COG1674	ftsk spoiiie
IHV08_RS16680	COG0433	COG0433 Predicted ATPase
IHV08_RS16685	COG4499	WXG100 protein secretion system (Wss), protein YukC
IHV08_RS16690	COG5417	Belongs to the EsaB family
IHV08_RS16695	COG4842	Belongs to the WXG100 family
IHV08_RS16700	COG2508	Transcriptional regulator
IHV08_RS16700	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IHV08_RS16705	COG0686	Belongs to the AlaDH PNT family
IHV08_RS16710	COG5634	Uncharacterized conserved protein (DUF2278)
IHV08_RS16715	COG3251	PFAM MbtH domain protein
IHV08_RS16720	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IHV08_RS16725	COG3433	isochorismatase activity
IHV08_RS16725	COG1535	isochorismatase
IHV08_RS16730	COG1021	2,3-dihydroxybenzoate-AMP ligase
IHV08_RS16735	COG1169	isochorismate synthase
IHV08_RS16740	COG1028	Short-chain dehydrogenase reductase Sdr
IHV08_RS16745	COG2819	hydrolase of the alpha beta superfamily
IHV08_RS16750	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IHV08_RS16755	COG1268	BioY protein
IHV08_RS16760	COG2056	Na+-H+ antiporter family
IHV08_RS16765	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IHV08_RS16770	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
IHV08_RS16775	COG3584	3D domain protein
IHV08_RS16790	COG1252	NADH dehydrogenase
IHV08_RS16795	COG0492	ferredoxin-NADP+ reductase activity
IHV08_RS16805	COG0516	GMP reductase activity
IHV08_RS16810	COG2808	Putative FMN-binding domain
IHV08_RS16815	COG0456	acetyltransferase
IHV08_RS16820	COG0316	Belongs to the HesB IscA family
IHV08_RS16825	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IHV08_RS16830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IHV08_RS16835	COG4844	belongs to the
IHV08_RS16840	COG1252	NADH dehydrogenase
IHV08_RS16845	COG4837	Protein of unknown function (DUF1462)
IHV08_RS16850	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
IHV08_RS16855	COG0823	Involved in the tonB-independent uptake of proteins
IHV08_RS16855	COG1506	peptidase
IHV08_RS16855	COG4946	Tricorn protease homolog
IHV08_RS16860	COG0083	homoserine kinase activity
IHV08_RS16865	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IHV08_RS16870	COG0460	homoserine dehydrogenase
IHV08_RS16875	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IHV08_RS16880	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IHV08_RS16885	COG0647	UMP catabolic process
IHV08_RS16890	COG2445	Protein of unknown function DUF86
IHV08_RS16895	COG4470	Protein conserved in bacteria
IHV08_RS16905	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IHV08_RS16910	COG0739	heme binding
IHV08_RS16920	COG3377	Domain of unknown function (DUF1805)
IHV08_RS16925	COG0737	Belongs to the 5'-nucleotidase family
IHV08_RS16930	COG0730	response to heat
IHV08_RS16935	COG1801	Protein of unknown function DUF72
IHV08_RS16945	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IHV08_RS16950	COG2508	Transcriptional regulator
IHV08_RS16955	COG2233	PERMEase
IHV08_RS16960	COG2233	PERMEase
IHV08_RS16965	COG3648	Uricase
IHV08_RS16965	COG3195	allantoin biosynthetic process
IHV08_RS16970	COG2351	hydroxyisourate hydrolase activity
IHV08_RS16980	COG2080	2 iron, 2 sulfur cluster binding
IHV08_RS16985	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IHV08_RS16990	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
IHV08_RS16995	COG2068	MobA-Related Protein
IHV08_RS17000	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IHV08_RS17005	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IHV08_RS17010	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IHV08_RS17020	COG2356	endonuclease I
IHV08_RS17025	COG3842	ATPase activity
IHV08_RS17030	COG2188	Transcriptional regulator
IHV08_RS17035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IHV08_RS17040	COG0395	ABC-type sugar transport system, permease component
IHV08_RS17045	COG1175	transmembrane transport
IHV08_RS17050	COG1653	transport
IHV08_RS17055	COG2222	sugar isomerase
IHV08_RS17060	COG0322	excinuclease ABC activity
IHV08_RS17065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IHV08_RS17100	COG0457	Tetratricopeptide repeat
IHV08_RS17105	COG5444	nuclease activity
IHV08_RS17115	COG1388	LysM domain
IHV08_RS17115	COG3409	Peptidoglycan-binding domain 1 protein
IHV08_RS17115	COG5632	N-Acetylmuramoyl-L-alanine amidase
IHV08_RS17120	COG4824	toxin secretion phage lysis holin
IHV08_RS17155	COG3953	SLT domain
IHV08_RS17155	COG5412	phage tail tape measure protein
IHV08_RS17250	COG0305	Participates in initiation and elongation during chromosome replication
IHV08_RS17275	COG3646	Phage regulatory protein
IHV08_RS17275	COG3645	SOS response
IHV08_RS17305	COG1396	sequence-specific DNA binding
IHV08_RS17315	COG4974	Belongs to the 'phage' integrase family
IHV08_RS17320	COG0719	Fe-S assembly protein
IHV08_RS17325	COG0822	iron-sulfur transferase activity
IHV08_RS17330	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IHV08_RS17335	COG0719	Fe-S assembly protein
IHV08_RS17340	COG0396	ATPase activity
IHV08_RS17350	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IHV08_RS17355	COG1464	Belongs to the NlpA lipoprotein family
IHV08_RS17360	COG2011	ABC-type metal ion transport system permease component
IHV08_RS17365	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IHV08_RS17375	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IHV08_RS17380	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IHV08_RS17390	COG0509	glycine decarboxylation via glycine cleavage system
IHV08_RS17395	COG1393	Belongs to the ArsC family
IHV08_RS17400	COG1960	acyl-CoA dehydrogenase activity
IHV08_RS17405	COG0183	Belongs to the thiolase family
IHV08_RS17410	COG1250	3-hydroxyacyl-CoA dehydrogenase
IHV08_RS17410	COG1024	Enoyl-CoA hydratase
IHV08_RS17420	COG0506	proline dehydrogenase activity
IHV08_RS17430	COG5577	PFAM Coat F domain
IHV08_RS17435	COG1846	Transcriptional regulator
IHV08_RS17440	COG0477	Major facilitator Superfamily
IHV08_RS17445	COG1942	4-Oxalocrotonate Tautomerase
IHV08_RS17450	COG1028	Short-chain dehydrogenase reductase Sdr
IHV08_RS17455	COG0583	DNA-binding transcription factor activity
IHV08_RS17465	COG1120	ATPase activity
IHV08_RS17480	COG1028	Short-chain dehydrogenase reductase Sdr
IHV08_RS17485	COG0783	Belongs to the Dps family
IHV08_RS17490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IHV08_RS17495	COG0745	RESPONSE REGULATOR receiver
IHV08_RS17500	COG2770	Histidine kinase
IHV08_RS17500	COG2205	protein histidine kinase activity
IHV08_RS17510	COG1309	transcriptional regulator
IHV08_RS17515	COG0114	fumarate hydratase activity
IHV08_RS17525	COG0697	spore germination
IHV08_RS17530	COG0814	amino acid
IHV08_RS17540	COG2197	response regulator
IHV08_RS17545	COG4585	Histidine kinase
IHV08_RS17550	COG4758	membrane
IHV08_RS17555	COG3595	metallopeptidase activity
IHV08_RS17560	COG1842	Phage shock protein A
IHV08_RS17565	COG4758	membrane
IHV08_RS17570	COG2814	Major facilitator Superfamily
IHV08_RS17575	COG2096	Adenosyltransferase
IHV08_RS17580	COG1120	ATPase activity
IHV08_RS17585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IHV08_RS17590	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IHV08_RS17595	COG1028	Short-chain dehydrogenase reductase Sdr
IHV08_RS17600	COG3386	PFAM SMP-30 Gluconolaconase
IHV08_RS17605	COG2205	protein histidine kinase activity
IHV08_RS17610	COG0745	RESPONSE REGULATOR receiver
IHV08_RS17620	COG1191	sigma factor activity
IHV08_RS17630	COG2140	Oxalate decarboxylase
IHV08_RS17640	COG0577	efflux transmembrane transporter activity
IHV08_RS17645	COG1136	(ABC) transporter
IHV08_RS17650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IHV08_RS17655	COG1120	ATPase activity
IHV08_RS17660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IHV08_RS17665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IHV08_RS17670	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IHV08_RS17675	COG0531	amino acid
IHV08_RS17685	COG1988	membrane-bound metal-dependent
IHV08_RS17690	COG1368	sulfuric ester hydrolase activity
IHV08_RS17695	COG1910	domain protein
IHV08_RS17700	COG0725	ABC transporter, periplasmic molybdate-binding protein
IHV08_RS17705	COG4149	molybdate abc transporter
IHV08_RS17710	COG0656	L-ascorbic acid biosynthetic process
IHV08_RS17720	COG0025	NhaP-type Na H and K H
IHV08_RS17725	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IHV08_RS17730	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IHV08_RS17735	COG3973	AAA domain
IHV08_RS17745	COG2860	membrane
IHV08_RS17750	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
IHV08_RS17755	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IHV08_RS17760	COG2217	Heavy metal translocating P-type atpase
IHV08_RS17765	COG2217	Heavy metal translocating P-type atpase
IHV08_RS17770	COG2608	mercury ion transmembrane transporter activity
IHV08_RS17775	COG1937	Protein conserved in bacteria
IHV08_RS17780	COG0673	inositol 2-dehydrogenase activity
IHV08_RS17785	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IHV08_RS17790	COG1289	transmembrane transporter activity
IHV08_RS17800	COG2076	Multidrug Resistance protein
IHV08_RS17805	COG1309	transcriptional regulator
IHV08_RS17810	COG1028	Short-chain dehydrogenase reductase Sdr
IHV08_RS17820	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IHV08_RS17825	COG0557	exoribonuclease II activity
IHV08_RS17830	COG1647	Serine aminopeptidase, S33
IHV08_RS17835	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IHV08_RS17840	COG0596	Alpha beta hydrolase
IHV08_RS17845	COG1476	TRANSCRIPTIONal
IHV08_RS17850	COG1396	sequence-specific DNA binding
IHV08_RS17855	COG1396	sequence-specific DNA binding
IHV08_RS17860	COG1733	regulation of RNA biosynthetic process
IHV08_RS17865	COG0840	transmembrane signaling receptor activity
IHV08_RS17870	COG1174	glycine betaine transport
IHV08_RS17875	COG1732	Glycine betaine
IHV08_RS17880	COG1174	glycine betaine transport
IHV08_RS17885	COG1125	glycine betaine transport
IHV08_RS17885	COG0517	IMP dehydrogenase activity
IHV08_RS17890	COG1510	regulation of RNA biosynthetic process
IHV08_RS17895	COG1174	glycine betaine transport
IHV08_RS17900	COG1732	Glycine betaine
IHV08_RS17905	COG1174	glycine betaine transport
IHV08_RS17910	COG1125	glycine betaine transport
IHV08_RS17910	COG0517	IMP dehydrogenase activity
IHV08_RS17915	COG1510	regulation of RNA biosynthetic process
IHV08_RS17920	COG2095	MarC family integral membrane protein
IHV08_RS17930	COG3064	Membrane
IHV08_RS17935	COG4640	response to antibiotic
IHV08_RS17940	COG0456	acetyltransferase
IHV08_RS17945	COG0148	phosphopyruvate hydratase activity
IHV08_RS17950	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IHV08_RS17955	COG0149	triose-phosphate isomerase activity
IHV08_RS17960	COG0126	phosphoglycerate kinase activity
IHV08_RS17965	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IHV08_RS17970	COG2390	Transcriptional regulator
IHV08_RS17975	COG2814	Major facilitator Superfamily
IHV08_RS17980	COG1609	Transcriptional regulator
IHV08_RS17985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IHV08_RS17990	COG0583	DNA-binding transcription factor activity
IHV08_RS17995	COG0697	spore germination
IHV08_RS18000	COG1113	amino acid transport
IHV08_RS18005	COG3858	chitin binding
IHV08_RS18010	COG1556	Lactate utilization protein
IHV08_RS18015	COG1139	Iron-sulfur cluster binding protein
IHV08_RS18020	COG0247	lactate metabolic process
IHV08_RS18025	COG2197	response regulator
IHV08_RS18030	COG4585	Histidine kinase
IHV08_RS18035	COG0842	Transport permease protein
IHV08_RS18040	COG1131	(ABC) transporter
IHV08_RS18045	COG0596	Alpha beta hydrolase
IHV08_RS18050	COG2208	phosphoserine phosphatase activity
IHV08_RS18055	COG3867	Arabinogalactan endo-beta-1,4-galactanase
IHV08_RS18060	COG1874	Beta-galactosidase
IHV08_RS18065	COG3833	ABC-type maltose transport systems, permease component
IHV08_RS18070	COG1175	transmembrane transport
IHV08_RS18075	COG2182	Extracellular solute-binding protein
IHV08_RS18080	COG1609	Transcriptional regulator
IHV08_RS18085	COG2186	Transcriptional regulator
IHV08_RS18090	COG1620	l-lactate permease
IHV08_RS18095	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
IHV08_RS18105	COG5039	Polysaccharide pyruvyl transferase
IHV08_RS18110	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IHV08_RS18115	COG0110	maltose O-acetyltransferase activity
IHV08_RS18120	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IHV08_RS18125	COG2244	polysaccharide biosynthetic process
IHV08_RS18130	COG1216	Glycosyl transferase, family 2
IHV08_RS18135	COG5039	Polysaccharide pyruvyl transferase
IHV08_RS18140	COG1216	Glycosyl transferase, family 2
IHV08_RS18150	COG0438	transferase activity, transferring glycosyl groups
IHV08_RS18155	COG1215	transferase activity, transferring glycosyl groups
IHV08_RS18160	COG0438	transferase activity, transferring glycosyl groups
IHV08_RS18165	COG1086	Polysaccharide biosynthesis protein
IHV08_RS18170	COG0489	protein tyrosine kinase activity
IHV08_RS18175	COG3944	biosynthesis protein
IHV08_RS18180	COG1396	sequence-specific DNA binding
IHV08_RS18185	COG2272	Belongs to the type-B carboxylesterase lipase family
IHV08_RS18195	COG3479	Phenolic acid decarboxylase
IHV08_RS18205	COG1794	racemase activity, acting on amino acids and derivatives
IHV08_RS18210	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IHV08_RS18215	COG1621	beta-fructofuranosidase activity
IHV08_RS18220	COG1621	beta-fructofuranosidase activity
IHV08_RS18225	COG0531	amino acid
IHV08_RS18230	COG1309	transcriptional regulator
IHV08_RS18235	COG2076	Multidrug Resistance protein
IHV08_RS18240	COG2076	Multidrug Resistance protein
IHV08_RS18250	COG0277	FAD linked oxidase domain protein
IHV08_RS18255	COG3621	Patatin-like phospholipase
IHV08_RS18265	COG0740	serine-type endopeptidase activity
IHV08_RS18270	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IHV08_RS18275	COG0366	Alpha amylase catalytic
IHV08_RS18280	COG1554	hydrolase, family 65, central catalytic
IHV08_RS18285	COG5521	maltodextrose utilization protein MalA
IHV08_RS18290	COG3833	ABC-type maltose transport systems, permease component
IHV08_RS18295	COG1175	transmembrane transport
IHV08_RS18300	COG2182	Extracellular solute-binding protein
IHV08_RS18310	COG1609	Transcriptional regulator
IHV08_RS18315	COG1611	Belongs to the LOG family
IHV08_RS18320	COG1694	Mazg nucleotide pyrophosphohydrolase
IHV08_RS18325	COG0659	secondary active sulfate transmembrane transporter activity
IHV08_RS18330	COG0288	reversible hydration of carbon dioxide
IHV08_RS18335	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IHV08_RS18340	COG0577	efflux transmembrane transporter activity
IHV08_RS18345	COG1136	(ABC) transporter
IHV08_RS18350	COG5002	protein histidine kinase activity
IHV08_RS18355	COG0745	RESPONSE REGULATOR receiver
IHV08_RS18365	COG2162	N-hydroxyarylamine O-acetyltransferase activity
IHV08_RS18370	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IHV08_RS18375	COG1481	regulation of sporulation
IHV08_RS18380	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IHV08_RS18385	COG1660	Displays ATPase and GTPase activities
IHV08_RS18390	COG1051	belongs to the nudix hydrolase family
IHV08_RS18395	COG0492	ferredoxin-NADP+ reductase activity
IHV08_RS18400	COG0791	NLP P60 protein
IHV08_RS18400	COG3883	PFAM NLP P60 protein
IHV08_RS18405	COG0457	Tetratricopeptide repeat
IHV08_RS18410	COG1132	(ABC) transporter
IHV08_RS18445	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IHV08_RS18445	COG0140	phosphoribosyl-ATP diphosphatase activity
IHV08_RS18450	COG0107	imidazoleglycerol-phosphate synthase activity
IHV08_RS18455	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IHV08_RS18460	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IHV08_RS18465	COG0131	Imidazoleglycerol-phosphate dehydratase
IHV08_RS18470	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IHV08_RS18475	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IHV08_RS18480	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IHV08_RS18485	COG4990	cell redox homeostasis
IHV08_RS18490	COG5297	Belongs to the glycosyl hydrolase family 6
IHV08_RS18495	COG0110	maltose O-acetyltransferase activity
IHV08_RS18500	COG0546	phosphoglycolate phosphatase activity
IHV08_RS18505	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
IHV08_RS18510	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IHV08_RS18515	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IHV08_RS18520	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IHV08_RS18525	COG0363	glucosamine-6-phosphate deaminase activity
IHV08_RS18530	COG2188	Transcriptional regulator
IHV08_RS18535	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IHV08_RS18540	COG1846	Transcriptional regulator
IHV08_RS18545	COG2124	cytochrome p450
IHV08_RS18555	COG1846	Transcriptional regulator
IHV08_RS18560	COG2814	Major facilitator Superfamily
IHV08_RS18565	COG1950	PFAM Membrane protein of
IHV08_RS18570	COG1983	PspC domain protein
IHV08_RS18575	COG3595	metallopeptidase activity
IHV08_RS18590	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IHV08_RS18595	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IHV08_RS18600	COG0556	nucleotide-excision repair
IHV08_RS18605	COG4897	Protein conserved in bacteria
IHV08_RS18610	COG0574	Belongs to the PEP-utilizing enzyme family
IHV08_RS18610	COG3848	Pyruvate phosphate dikinase
IHV08_RS18615	COG1309	transcriptional regulator
IHV08_RS18620	COG2814	Major facilitator Superfamily
IHV08_RS18625	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IHV08_RS18635	COG0793	Belongs to the peptidase S41A family
IHV08_RS18635	COG3409	Peptidoglycan-binding domain 1 protein
IHV08_RS18640	COG2177	Part of the ABC transporter FtsEX involved in
IHV08_RS18645	COG2884	Cell division ATP-binding protein ftsE
IHV08_RS18650	COG2010	Cytochrome c
IHV08_RS18655	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IHV08_RS18665	COG0653	protein targeting
IHV08_RS18670	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IHV08_RS18685	COG1516	flagellar protein fliS
IHV08_RS18690	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IHV08_RS18695	COG1334	flagellar protein FlaG
IHV08_RS18700	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IHV08_RS18705	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IHV08_RS18710	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
IHV08_RS18720	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IHV08_RS18725	COG4786	Flagellar basal body rod
IHV08_RS18725	COG1256	bacterial-type flagellum assembly
IHV08_RS18730	COG3418	PFAM FlgN family protein
IHV08_RS18735	COG2747	anti-sigma28 factor FlgM
IHV08_RS18745	COG1040	competence protein
IHV08_RS18755	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IHV08_RS18760	COG1307	EDD domain protein, DegV family
IHV08_RS18765	COG2197	response regulator
IHV08_RS18770	COG4585	Histidine kinase
IHV08_RS18775	COG1739	Uncharacterized protein family UPF0029
IHV08_RS18780	COG1316	TRANSCRIPTIONal
IHV08_RS18785	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IHV08_RS18790	COG0438	transferase activity, transferring glycosyl groups
IHV08_RS18795	COG1215	transferase activity, transferring glycosyl groups
IHV08_RS18800	COG3206	protein involved in exopolysaccharide biosynthesis
IHV08_RS18805	COG3307	-O-antigen
IHV08_RS18810	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IHV08_RS18815	COG0297	glycogen (starch) synthase activity
IHV08_RS18815	COG0438	transferase activity, transferring glycosyl groups
IHV08_RS18820	COG2244	polysaccharide biosynthetic process
IHV08_RS18835	COG2247	cell wall binding repeat
IHV08_RS18835	COG0860	N-Acetylmuramoyl-L-alanine amidase
IHV08_RS18840	COG2247	cell wall binding repeat
IHV08_RS18840	COG2385	sporulation resulting in formation of a cellular spore
IHV08_RS18850	COG1316	TRANSCRIPTIONal
IHV08_RS18855	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IHV08_RS18875	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IHV08_RS18880	COG1134	teichoic acid transport
IHV08_RS18885	COG1682	transport, permease protein
IHV08_RS18890	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IHV08_RS18890	COG1215	transferase activity, transferring glycosyl groups
IHV08_RS18895	COG0463	Glycosyl transferase, family 2
IHV08_RS18940	COG4193	domain, Protein
IHV08_RS18945	COG1482	cell wall glycoprotein biosynthetic process
IHV08_RS18950	COG0697	spore germination
IHV08_RS18955	COG0814	amino acid
IHV08_RS18965	COG2814	Major facilitator Superfamily
IHV08_RS18970	COG1316	TRANSCRIPTIONal
IHV08_RS18975	COG0561	phosphatase activity
IHV08_RS18980	COG0791	NLP P60 protein
IHV08_RS18990	COG2843	Capsule synthesis protein
IHV08_RS19000	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IHV08_RS19005	COG1609	Transcriptional regulator
IHV08_RS19010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IHV08_RS19015	COG1869	D-ribose catabolic process
IHV08_RS19020	COG1129	ABC transporter
IHV08_RS19025	COG1172	Belongs to the binding-protein-dependent transport system permease family
IHV08_RS19030	COG1879	ABC-type sugar transport system periplasmic component
IHV08_RS19035	COG3103	Sh3 type 3 domain protein
IHV08_RS19045	COG2249	NAD(P)H dehydrogenase (quinone) activity
IHV08_RS19050	COG3527	Alpha-acetolactate decarboxylase
IHV08_RS19055	COG0028	Belongs to the TPP enzyme family
IHV08_RS19060	COG0583	DNA-binding transcription factor activity
IHV08_RS19065	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IHV08_RS19080	COG5337	Spore coat protein CotH
IHV08_RS19090	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IHV08_RS19100	COG0405	Gamma-glutamyltransferase
IHV08_RS19105	COG1522	sequence-specific DNA binding
IHV08_RS19110	COG2059	Chromate
IHV08_RS19115	COG2059	Chromate
IHV08_RS19125	COG0655	NAD(P)H dehydrogenase (quinone) activity
IHV08_RS19130	COG0583	DNA-binding transcription factor activity
IHV08_RS19145	COG5444	nuclease activity
IHV08_RS19165	COG3878	Protein conserved in bacteria
IHV08_RS19170	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IHV08_RS19175	COG4464	protein tyrosine phosphatase activity
IHV08_RS19180	COG0489	protein tyrosine kinase activity
IHV08_RS19185	COG3944	biosynthesis protein
IHV08_RS19195	COG4715	Zinc finger, swim domain protein
IHV08_RS19200	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IHV08_RS19205	COG0561	phosphatase activity
IHV08_RS19210	COG1349	DNA-binding transcription factor activity
IHV08_RS19215	COG0629	single-stranded DNA binding
IHV08_RS19230	COG3764	Sortase (surface protein transpeptidase)
IHV08_RS19240	COG3279	Response regulator of the LytR AlgR family
IHV08_RS19245	COG0745	RESPONSE REGULATOR receiver
IHV08_RS19245	COG2972	Histidine kinase
IHV08_RS19250	COG1970	mechanosensitive ion channel activity
IHV08_RS19255	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IHV08_RS19260	COG0457	Tetratricopeptide repeat
IHV08_RS19265	COG4786	Flagellar basal body rod
IHV08_RS19270	COG4786	Flagellar basal body rod
IHV08_RS19275	COG1077	Cell shape determining protein MreB Mrl
IHV08_RS19280	COG1609	Transcriptional regulator
IHV08_RS19290	COG1846	Transcriptional regulator
IHV08_RS19295	COG2814	Major facilitator Superfamily
IHV08_RS19300	COG3420	alginic acid biosynthetic process
IHV08_RS19305	COG1953	Uracil, thiamine, allantoin
IHV08_RS19310	COG0477	Major facilitator Superfamily
IHV08_RS19315	COG1335	isochorismatase
IHV08_RS19325	COG0004	ammonium transporteR
IHV08_RS19330	COG0347	Belongs to the P(II) protein family
IHV08_RS19335	COG0671	phosphoesterase, PA-phosphatase related
IHV08_RS19345	COG0739	heme binding
IHV08_RS19350	COG1247	-acetyltransferase
IHV08_RS19370	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IHV08_RS19375	COG0789	Transcriptional regulator
IHV08_RS19385	COG2910	NAD(P)H-binding
IHV08_RS19390	COG1959	2 iron, 2 sulfur cluster binding
IHV08_RS19395	COG0804	urea catabolic process
IHV08_RS19400	COG0832	Belongs to the urease beta subunit family
IHV08_RS19405	COG0831	urea catabolic process
IHV08_RS19420	COG3237	CsbD-like
IHV08_RS19425	COG1994	Peptidase M50
IHV08_RS19430	COG0457	Tetratricopeptide repeat
IHV08_RS19435	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IHV08_RS19440	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IHV08_RS19450	COG2304	oxidoreductase activity
IHV08_RS19460	COG2304	oxidoreductase activity
IHV08_RS19465	COG2385	sporulation resulting in formation of a cellular spore
IHV08_RS19470	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IHV08_RS19480	COG4836	Membrane
IHV08_RS19490	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IHV08_RS19495	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IHV08_RS19500	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IHV08_RS19505	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IHV08_RS19510	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IHV08_RS19515	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IHV08_RS19525	COG0356	it plays a direct role in the translocation of protons across the membrane
IHV08_RS19535	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IHV08_RS19540	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IHV08_RS19545	COG4475	Protein of unknown function (DUF436)
IHV08_RS19550	COG0698	ribose 5-phosphate isomerase
IHV08_RS19555	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IHV08_RS19560	COG1971	Probably functions as a manganese efflux pump
IHV08_RS19565	COG0009	L-threonylcarbamoyladenylate synthase
IHV08_RS19570	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IHV08_RS19590	COG2890	protein-(glutamine-N5) methyltransferase activity
IHV08_RS19595	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IHV08_RS19600	COG0346	lactoylglutathione lyase activity
IHV08_RS19605	COG0789	Transcriptional regulator
IHV08_RS19610	COG0679	Auxin Efflux Carrier
IHV08_RS19615	COG0281	malic enzyme
IHV08_RS19620	COG1435	thymidine kinase activity
IHV08_RS19630	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IHV08_RS19640	COG1494	fructose-1,6-bisphosphatase
IHV08_RS19645	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IHV08_RS19650	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IHV08_RS19655	COG0191	fructose-bisphosphate aldolase activity
IHV08_RS19660	COG2204	response regulator
IHV08_RS19665	COG4821	SIS domain
IHV08_RS19670	COG0504	CTP synthase activity
IHV08_RS19675	COG3343	RNA polymerase activity
IHV08_RS19680	COG1960	acyl-CoA dehydrogenase activity
IHV08_RS19685	COG0247	lactate metabolic process
IHV08_RS19685	COG2181	nitrate reductase activity
IHV08_RS19690	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IHV08_RS19695	COG4294	response to UV
IHV08_RS19705	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IHV08_RS19710	COG1132	(ABC) transporter
IHV08_RS19715	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IHV08_RS19720	COG2181	nitrate reductase activity
IHV08_RS19725	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
IHV08_RS19730	COG1140	nitrate reductase beta subunit
IHV08_RS19735	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IHV08_RS19740	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IHV08_RS19750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IHV08_RS19755	COG2223	nitrite transmembrane transporter activity
IHV08_RS19760	COG0018	arginyl-trna synthetase
IHV08_RS19765	COG4506	Protein conserved in bacteria
IHV08_RS19780	COG0535	radical SAM domain protein
IHV08_RS19790	COG1131	(ABC) transporter
IHV08_RS19795	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IHV08_RS19800	COG0612	Peptidase, M16
IHV08_RS19805	COG0612	Peptidase, M16
IHV08_RS19815	COG3391	amine dehydrogenase activity
IHV08_RS19820	COG3391	amine dehydrogenase activity
IHV08_RS19825	COG0457	Tetratricopeptide repeat
IHV08_RS19855	COG1131	(ABC) transporter
IHV08_RS19865	COG0010	Belongs to the arginase family
IHV08_RS19870	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IHV08_RS19875	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IHV08_RS19885	COG1994	Peptidase M50
IHV08_RS19890	COG1942	4-Oxalocrotonate Tautomerase
IHV08_RS19895	COG1846	Transcriptional regulator
IHV08_RS19900	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IHV08_RS19905	COG0477	Major facilitator Superfamily
IHV08_RS19910	COG1959	2 iron, 2 sulfur cluster binding
IHV08_RS19915	COG3465	dGTPase activity
IHV08_RS19920	COG1078	dGTPase activity
IHV08_RS19925	COG4844	belongs to the
IHV08_RS19935	COG0697	spore germination
IHV08_RS19940	COG0095	Lipoate-protein ligase
IHV08_RS19945	COG0583	DNA-binding transcription factor activity
IHV08_RS19950	COG0280	phosphate acetyltransferase
IHV08_RS19955	COG3253	May function as heme-dependent peroxidase
IHV08_RS19960	COG1028	Short-chain dehydrogenase reductase Sdr
IHV08_RS19965	COG0436	Aminotransferase
IHV08_RS19970	COG2814	Major facilitator Superfamily
IHV08_RS19975	COG0151	Belongs to the GarS family
IHV08_RS19980	COG1028	Short-chain dehydrogenase reductase Sdr
IHV08_RS19985	COG1917	Cupin 2, conserved barrel domain protein
IHV08_RS19990	COG0077	Prephenate dehydratase
IHV08_RS19995	COG2814	Major facilitator Superfamily
IHV08_RS20000	COG0833	amino acid
IHV08_RS20005	COG4187	Peptidase family M20/M25/M40
IHV08_RS20010	COG1012	belongs to the aldehyde dehydrogenase family
IHV08_RS20015	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IHV08_RS20025	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
IHV08_RS20030	COG1091	dTDP-4-dehydrorhamnose reductase activity
IHV08_RS20035	COG1088	dTDP-glucose 4,6-dehydratase activity
IHV08_RS20040	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IHV08_RS20045	COG3980	spore coat polysaccharide biosynthesis protein
IHV08_RS20050	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
IHV08_RS20055	COG2089	acid synthase
IHV08_RS20060	COG0456	acetyltransferase
IHV08_RS20065	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IHV08_RS20070	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IHV08_RS20075	COG0463	Glycosyl transferase, family 2
IHV08_RS20085	COG2363	Small membrane protein
IHV08_RS20090	COG2233	PERMEase
IHV08_RS20100	COG1012	belongs to the aldehyde dehydrogenase family
IHV08_RS20105	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IHV08_RS20110	COG1216	Glycosyl transferase, family 2
IHV08_RS20125	COG1695	Transcriptional regulator
IHV08_RS20130	COG0351	phosphomethylpyrimidine kinase
IHV08_RS20140	COG1621	beta-fructofuranosidase activity
IHV08_RS20145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IHV08_RS20145	COG1263	PTS System
IHV08_RS20150	COG2116	formate transmembrane transporter activity
IHV08_RS20155	COG3711	transcriptional antiterminator
IHV08_RS20165	COG1404	Belongs to the peptidase S8 family
IHV08_RS20170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IHV08_RS20175	COG0778	Nitroreductase
IHV08_RS20180	COG0772	Belongs to the SEDS family
IHV08_RS20190	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IHV08_RS20195	COG1845	cytochrome c oxidase, subunit III
IHV08_RS20200	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IHV08_RS20205	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IHV08_RS20210	COG2261	transglycosylase associated protein
IHV08_RS20215	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
IHV08_RS20220	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IHV08_RS20225	COG2246	polysaccharide biosynthetic process
IHV08_RS20230	COG1309	transcriptional regulator
IHV08_RS20240	COG3162	membrane
IHV08_RS20245	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IHV08_RS20250	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IHV08_RS20255	COG2837	iron assimilation
IHV08_RS20260	COG2822	iron ion transport
IHV08_RS20265	COG0672	)-iron permease
IHV08_RS20270	COG0352	thiamine-phosphate diphosphorylase activity
IHV08_RS20275	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IHV08_RS20280	COG0583	DNA-binding transcription factor activity
IHV08_RS20285	COG1380	Effector of murein hydrolase LrgA
IHV08_RS20290	COG1346	cytolysis
IHV08_RS20295	COG2814	Major facilitator Superfamily
IHV08_RS20300	COG4895	conserved protein (DUF2196)
IHV08_RS20305	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IHV08_RS20310	COG0346	lactoylglutathione lyase activity
IHV08_RS20320	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IHV08_RS20325	COG1404	Belongs to the peptidase S8 family
IHV08_RS20330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IHV08_RS20330	COG1263	PTS System
IHV08_RS20335	COG3711	transcriptional antiterminator
IHV08_RS20340	COG1442	glycosyl transferase family 8
IHV08_RS20345	COG5522	Integral membrane protein (intg_mem_TP0381)
IHV08_RS20350	COG1846	Transcriptional regulator
IHV08_RS20355	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IHV08_RS20360	COG2234	aminopeptidase activity
IHV08_RS20375	COG2814	Major facilitator Superfamily
IHV08_RS20380	COG2357	RelA SpoT domain protein
IHV08_RS20385	COG1575	Belongs to the MenA family. Type 1 subfamily
IHV08_RS20400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IHV08_RS20405	COG1696	Membrane protein involved in D-alanine export
IHV08_RS20410	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IHV08_RS20415	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IHV08_RS20420	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
IHV08_RS20425	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IHV08_RS20430	COG1486	melibiose metabolic process
IHV08_RS20435	COG1447	Phosphotransferase system cellobiose-specific component IIA
IHV08_RS20440	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IHV08_RS20445	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IHV08_RS20450	COG3711	transcriptional antiterminator
IHV08_RS20450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IHV08_RS20460	COG2094	Belongs to the DNA glycosylase MPG family
IHV08_RS20465	COG0753	catalase activity
IHV08_RS20470	COG2814	Major facilitator Superfamily
IHV08_RS20475	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
IHV08_RS20480	COG1131	(ABC) transporter
IHV08_RS20500	COG1595	DNA-templated transcription, initiation
IHV08_RS20505	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IHV08_RS20510	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IHV08_RS20515	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IHV08_RS20520	COG4988	ABC transporter
IHV08_RS20525	COG1294	oxidase, subunit
IHV08_RS20530	COG1271	oxidase subunit
IHV08_RS20535	COG3493	citrate carrier protein
IHV08_RS20540	COG0501	Belongs to the peptidase M48B family
IHV08_RS20550	COG0726	polysaccharide deacetylase
IHV08_RS20555	COG3842	ATPase activity
IHV08_RS20560	COG2508	Transcriptional regulator
IHV08_RS20565	COG1012	belongs to the aldehyde dehydrogenase family
IHV08_RS20570	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IHV08_RS20580	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IHV08_RS20590	COG4585	Histidine kinase
IHV08_RS20595	COG2197	response regulator
IHV08_RS20600	COG2195	Cleaves the N-terminal amino acid of tripeptides
IHV08_RS20615	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IHV08_RS20620	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IHV08_RS20625	COG1028	Short-chain dehydrogenase reductase Sdr
IHV08_RS20630	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IHV08_RS20635	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IHV08_RS20640	COG2610	gluconate transmembrane transporter activity
IHV08_RS20645	COG0500	methyltransferase
IHV08_RS20650	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IHV08_RS20665	COG0753	catalase activity
IHV08_RS20665	COG0693	protein deglycase activity
IHV08_RS20670	COG2851	Citrate transporter
IHV08_RS20675	COG2273	Hydrolase Family 16
IHV08_RS20680	COG3711	transcriptional antiterminator
IHV08_RS20690	COG2270	Major facilitator Superfamily
IHV08_RS20695	COG0513	Belongs to the DEAD box helicase family
IHV08_RS20700	COG2755	lipolytic protein G-D-S-L family
IHV08_RS20700	COG3401	FG-GAP repeat protein
IHV08_RS20750	COG3209	COG3209 Rhs family protein
IHV08_RS20755	COG0697	spore germination
IHV08_RS20760	COG0589	response to stress
IHV08_RS20765	COG2723	6-phospho-beta-galactosidase activity
IHV08_RS20770	COG1263	PTS System
IHV08_RS20770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IHV08_RS20770	COG2190	(PTS) system
IHV08_RS20805	COG5444	nuclease activity
IHV08_RS20820	COG3507	Belongs to the glycosyl hydrolase 43 family
IHV08_RS20830	COG2986	histidine ammonia-lyase
IHV08_RS20835	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IHV08_RS20840	COG1228	amidohydrolase
IHV08_RS20845	COG0010	Belongs to the arginase family
IHV08_RS20850	COG0833	amino acid
IHV08_RS20855	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
IHV08_RS20860	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IHV08_RS20865	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IHV08_RS20870	COG2390	Transcriptional regulator
IHV08_RS20880	COG3192	ethanolamine utilization protein
IHV08_RS20885	COG2079	MmgE PrpD family protein
IHV08_RS20890	COG1473	amidohydrolase
IHV08_RS20895	COG1126	abc transporter atp-binding protein
IHV08_RS20900	COG0765	amino acid transport
IHV08_RS20905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IHV08_RS20910	COG0456	acetyltransferase
IHV08_RS20915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IHV08_RS20920	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
IHV08_RS20925	COG0561	phosphatase activity
IHV08_RS20955	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IHV08_RS20960	COG5294	Protein conserved in bacteria
IHV08_RS20965	COG0577	efflux transmembrane transporter activity
IHV08_RS20970	COG1136	(ABC) transporter
IHV08_RS20975	COG2205	protein histidine kinase activity
IHV08_RS20980	COG0745	RESPONSE REGULATOR receiver
IHV08_RS20985	COG0191	fructose-bisphosphate aldolase activity
IHV08_RS20990	COG1082	Xylose isomerase domain protein TIM barrel
IHV08_RS20995	COG1082	Xylose isomerase domain protein TIM barrel
IHV08_RS21000	COG0673	inositol 2-dehydrogenase activity
IHV08_RS21005	COG2814	Major facilitator Superfamily
IHV08_RS21010	COG1082	Xylose isomerase domain protein TIM barrel
IHV08_RS21015	COG3962	Belongs to the TPP enzyme family
IHV08_RS21020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IHV08_RS21025	COG3718	enzyme involved in inositol metabolism
IHV08_RS21030	COG1012	belongs to the aldehyde dehydrogenase family
IHV08_RS21035	COG1349	DNA-binding transcription factor activity
IHV08_RS21040	COG0667	Aldo Keto reductase
IHV08_RS21055	COG2814	Major facilitator Superfamily
IHV08_RS21060	COG0326	Molecular chaperone. Has ATPase activity
IHV08_RS21070	COG1028	Short-chain dehydrogenase reductase Sdr
IHV08_RS21075	COG1309	transcriptional regulator
IHV08_RS21080	COG1012	belongs to the aldehyde dehydrogenase family
IHV08_RS21090	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IHV08_RS21100	COG1714	RDD family
IHV08_RS21105	COG2311	Membrane
IHV08_RS21110	COG1917	Cupin 2, conserved barrel domain protein
IHV08_RS21115	COG1309	transcriptional regulator
IHV08_RS21120	COG1028	Short-chain dehydrogenase reductase Sdr
IHV08_RS21125	COG1846	Transcriptional regulator
IHV08_RS21130	COG1380	Effector of murein hydrolase LrgA
IHV08_RS21135	COG1346	cytolysis
IHV08_RS21140	COG5039	Polysaccharide pyruvyl transferase
IHV08_RS21145	COG1929	Belongs to the glycerate kinase type-1 family
IHV08_RS21150	COG1802	Transcriptional regulator
IHV08_RS21155	COG1070	Carbohydrate kinase
IHV08_RS21160	COG2610	gluconate transmembrane transporter activity
IHV08_RS21165	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IHV08_RS21170	COG0450	alkyl hydroperoxide reductase
IHV08_RS21175	COG3634	alkyl hydroperoxide reductase activity
IHV08_RS21185	COG2723	6-phospho-beta-galactosidase activity
IHV08_RS21195	COG2188	Transcriptional regulator
IHV08_RS21215	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
IHV08_RS21255	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IHV08_RS21270	COG1063	alcohol dehydrogenase
IHV08_RS21290	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
IHV08_RS21295	COG0456	acetyltransferase
IHV08_RS21300	COG0457	Tetratricopeptide repeat
IHV08_RS21310	COG0010	Belongs to the arginase family
IHV08_RS21315	COG0833	amino acid
IHV08_RS21320	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IHV08_RS21325	COG3829	transcription factor binding
IHV08_RS21330	COG5002	protein histidine kinase activity
IHV08_RS21335	COG0745	RESPONSE REGULATOR receiver
IHV08_RS21355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IHV08_RS21360	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
IHV08_RS21365	COG4853	Protein conserved in bacteria
IHV08_RS21370	COG4863	YycH protein
IHV08_RS21375	COG5002	protein histidine kinase activity
IHV08_RS21380	COG0745	RESPONSE REGULATOR receiver
IHV08_RS21410	COG0346	lactoylglutathione lyase activity
IHV08_RS21415	COG0305	Participates in initiation and elongation during chromosome replication
IHV08_RS21430	COG3093	addiction module antidote protein HigA
IHV08_RS21435	COG2807	transmembrane transport
IHV08_RS21440	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IHV08_RS21445	COG0359	binds to the 23S rRNA
IHV08_RS21450	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
IHV08_RS21455	COG4241	membrane
IHV08_RS21465	COG5577	PFAM Coat F domain
IHV08_RS21470	COG1733	regulation of RNA biosynthetic process
IHV08_RS21475	COG1227	inorganic diphosphatase activity
IHV08_RS21490	COG2271	Major facilitator Superfamily
IHV08_RS21495	COG4978	Transcriptional regulator
IHV08_RS21495	COG0789	Transcriptional regulator
IHV08_RS21505	COG4319	ketosteroid isomerase
IHV08_RS21510	COG1357	PFAM Pentapeptide repeats (8 copies)
IHV08_RS21515	COG2814	Major facilitator Superfamily
IHV08_RS21520	COG0583	DNA-binding transcription factor activity
IHV08_RS21525	COG2153	protein acetylation
IHV08_RS21535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IHV08_RS21540	COG1846	Transcriptional regulator
IHV08_RS21545	COG2153	protein acetylation
IHV08_RS21550	COG2364	Membrane
IHV08_RS21555	COG0456	acetyltransferase
IHV08_RS21560	COG2315	Protein conserved in bacteria
IHV08_RS21565	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IHV08_RS21575	COG2814	Major facilitator Superfamily
IHV08_RS21585	COG1331	Highly conserved protein containing a thioredoxin domain
IHV08_RS21590	COG0789	Transcriptional regulator
IHV08_RS21595	COG0697	spore germination
IHV08_RS21600	COG1331	Highly conserved protein containing a thioredoxin domain
IHV08_RS21605	COG1266	CAAX protease self-immunity
IHV08_RS21610	COG2814	Major facilitator Superfamily
IHV08_RS21610	COG0477	Major facilitator Superfamily
IHV08_RS21615	COG0110	maltose O-acetyltransferase activity
IHV08_RS21620	COG0346	lactoylglutathione lyase activity
IHV08_RS21625	COG1609	Transcriptional regulator
IHV08_RS21630	COG0708	Exodeoxyribonuclease III
IHV08_RS21635	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IHV08_RS21640	COG0629	single-stranded DNA binding
IHV08_RS21645	COG0360	Binds together with S18 to 16S ribosomal RNA
IHV08_RS21650	COG0012	GTP binding
IHV08_RS21655	COG0243	molybdopterin cofactor binding
IHV08_RS21660	COG4481	Protein conserved in bacteria
IHV08_RS21665	COG3949	Membrane
IHV08_RS21675	COG1475	DNA binding
IHV08_RS21680	COG1192	Involved in chromosome partitioning
IHV08_RS21690	COG1475	DNA binding
IHV08_RS21695	COG0357	Ribosomal RNA small subunit methyltransferase G
IHV08_RS21700	COG0445	tRNA wobble uridine modification
IHV08_RS21705	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IHV08_RS21710	COG1847	R3H domain protein
IHV08_RS21715	COG0706	membrane insertase activity
IHV08_RS21720	COG0594	ribonuclease P activity