locus-tag	class	description
JS609_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JS609_RS00010	COG0592	DNA-directed DNA polymerase activity
JS609_RS00015	COG2501	S4 domain
JS609_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JS609_RS00030	COG0187	DNA topoisomerase II activity
JS609_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JS609_RS00070	COG0516	GMP reductase activity
JS609_RS00070	COG0517	IMP dehydrogenase activity
JS609_RS00075	COG1686	Belongs to the peptidase S11 family
JS609_RS00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
JS609_RS00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
JS609_RS00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JS609_RS00100	COG1428	Deoxynucleoside kinase
JS609_RS00105	COG1428	Deoxynucleoside kinase
JS609_RS00110	COG1388	LysM domain
JS609_RS00110	COG3858	chitin binding
JS609_RS00115	COG1335	isochorismatase
JS609_RS00120	COG0590	tRNA wobble adenosine to inosine editing
JS609_RS00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JS609_RS00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JS609_RS00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JS609_RS00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
JS609_RS00190	COG3853	Toxic anion resistance protein (TelA)
JS609_RS00195	COG1982	Orn Lys Arg decarboxylase major
JS609_RS00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JS609_RS00205	COG3870	Protein conserved in bacteria
JS609_RS00210	COG1728	Protein conserved in bacteria
JS609_RS00215	COG0470	DNA polymerase III
JS609_RS00220	COG1774	PSP1 C-terminal conserved region
JS609_RS00225	COG4467	Involved in initiation control of chromosome replication
JS609_RS00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JS609_RS00235	COG2827	Endonuclease containing a URI domain
JS609_RS00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JS609_RS00245	COG2002	toxin-antitoxin pair type II binding
JS609_RS00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JS609_RS00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JS609_RS00255	COG0084	hydrolase, TatD family'
JS609_RS00260	COG3583	domain protein
JS609_RS00260	COG3584	3D domain protein
JS609_RS00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JS609_RS00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JS609_RS00280	COG4466	Protein conserved in bacteria
JS609_RS00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JS609_RS00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JS609_RS00300	COG0251	oxidation-reduction process
JS609_RS00305	COG2088	sporulation resulting in formation of a cellular spore
JS609_RS00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JS609_RS00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JS609_RS00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JS609_RS00325	COG0193	aminoacyl-tRNA hydrolase activity
JS609_RS00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JS609_RS00340	COG2002	toxin-antitoxin pair type II binding
JS609_RS00345	COG2244	polysaccharide biosynthetic process
JS609_RS00350	COG3956	TIGRFAM MazG family protein
JS609_RS00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JS609_RS00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
JS609_RS00375	COG1098	S1 RNA binding domain
JS609_RS00390	COG2208	phosphoserine phosphatase activity
JS609_RS00395	COG2304	oxidoreductase activity
JS609_RS00400	COG0515	serine threonine protein kinase
JS609_RS00405	COG0037	tRNA processing
JS609_RS00410	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
JS609_RS00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JS609_RS00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
JS609_RS00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JS609_RS00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JS609_RS00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JS609_RS00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JS609_RS00445	COG0512	Glutamine amidotransferase of anthranilate synthase
JS609_RS00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JS609_RS00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JS609_RS00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JS609_RS00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JS609_RS00470	COG1396	sequence-specific DNA binding
JS609_RS00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JS609_RS00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JS609_RS00560	COG4463	regulation of RNA biosynthetic process
JS609_RS00565	COG3880	PFAM UvrB UvrC protein
JS609_RS00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
JS609_RS00575	COG0542	response to heat
JS609_RS00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JS609_RS00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
JS609_RS00590	COG4956	integral membrane protein (PIN domain superfamily)
JS609_RS00595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JS609_RS00600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
JS609_RS00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JS609_RS00610	COG1045	serine acetyltransferase
JS609_RS00615	COG0215	cysteine-tRNA ligase activity
JS609_RS00620	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JS609_RS00625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JS609_RS00630	COG3688	RNA-binding protein containing a PIN domain
JS609_RS00635	COG1595	DNA-templated transcription, initiation
JS609_RS00645	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JS609_RS00650	COG0250	Participates in transcription elongation, termination and antitermination
JS609_RS00660	COG0081	regulation of translation
JS609_RS00665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JS609_RS00675	COG2813	Specifically methylates the guanine in position
JS609_RS00680	COG0085	RNA polymerase activity
JS609_RS00685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JS609_RS00690	COG1358	cellular component organization or biogenesis
JS609_RS00695	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JS609_RS00700	COG0049	tRNA binding
JS609_RS00705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JS609_RS00710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JS609_RS00715	COG0596	Alpha beta hydrolase
JS609_RS00725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JS609_RS00730	COG0088	Forms part of the polypeptide exit tunnel
JS609_RS00740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JS609_RS00760	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JS609_RS00770	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JS609_RS00775	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JS609_RS00785	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JS609_RS00795	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JS609_RS00800	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JS609_RS00805	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JS609_RS00810	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JS609_RS00820	COG0200	Binds to the 23S rRNA
JS609_RS00825	COG0201	protein transport
JS609_RS00830	COG0563	adenylate kinase activity
JS609_RS00835	COG0024	Methionine aminopeptidase
JS609_RS00840	COG2163	COG2163 Ribosomal protein L14E L6E L27E
JS609_RS00850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JS609_RS00855	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JS609_RS00860	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JS609_RS00865	COG0202	RNA polymerase activity
JS609_RS00870	COG0203	ribosomal protein L17
JS609_RS00875	COG1122	ATPase activity
JS609_RS00880	COG1122	ATPase activity
JS609_RS00885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JS609_RS00890	COG0101	tRNA pseudouridine synthase activity
JS609_RS00895	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JS609_RS00900	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JS609_RS00905	COG2226	methyltransferase
JS609_RS00915	COG0860	N-Acetylmuramoyl-L-alanine amidase
JS609_RS00920	COG0489	protein tyrosine kinase activity
JS609_RS00930	COG2194	sulfuric ester hydrolase activity
JS609_RS00935	COG0726	polysaccharide deacetylase
JS609_RS01020	COG0659	secondary active sulfate transmembrane transporter activity
JS609_RS01025	COG0385	Bile acid
JS609_RS01030	COG2819	hydrolase of the alpha beta superfamily
JS609_RS01035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JS609_RS01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JS609_RS01045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JS609_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JS609_RS01050	COG2207	Transcriptional regulator
JS609_RS01055	COG3876	Protein conserved in bacteria
JS609_RS01060	COG1472	Belongs to the glycosyl hydrolase 3 family
JS609_RS01065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JS609_RS01070	COG1263	PTS System
JS609_RS01070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JS609_RS01075	COG1737	Transcriptional regulator
JS609_RS01080	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JS609_RS01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JS609_RS01090	COG1683	Conserved Protein
JS609_RS01120	COG1595	DNA-templated transcription, initiation
JS609_RS01125	COG5662	AntiSigma factor
JS609_RS01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JS609_RS01135	COG4856	YbbR-like protein
JS609_RS01140	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JS609_RS01145	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JS609_RS01155	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JS609_RS01160	COG2169	Transcriptional regulator
JS609_RS01165	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JS609_RS01170	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JS609_RS01175	COG3002	Belongs to the UPF0753 family
JS609_RS01180	COG0288	reversible hydration of carbon dioxide
JS609_RS01190	COG5609	conserved protein (DUF2294)
JS609_RS01195	COG0640	Transcriptional regulator
JS609_RS01200	COG2814	Major facilitator Superfamily
JS609_RS01220	COG1136	(ABC) transporter
JS609_RS01245	COG1113	amino acid transport
JS609_RS01260	COG2602	Beta-lactamase
JS609_RS01265	COG2124	cytochrome p450
JS609_RS01275	COG0531	amino acid
JS609_RS01280	COG0584	glycerophosphoryl diester phosphodiesterase
JS609_RS01285	COG2271	Major facilitator Superfamily
JS609_RS01295	COG0456	acetyltransferase
JS609_RS01295	COG1846	Transcriptional regulator
JS609_RS01300	COG2271	Major facilitator Superfamily
JS609_RS01310	COG3409	Peptidoglycan-binding domain 1 protein
JS609_RS01315	COG0697	spore germination
JS609_RS01320	COG1917	Cupin 2, conserved barrel domain protein
JS609_RS01320	COG2207	Transcriptional regulator
JS609_RS01325	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
JS609_RS01330	COG3591	Belongs to the peptidase S1B family
JS609_RS01340	COG0596	Alpha beta hydrolase
JS609_RS01345	COG1183	phosphatidylcholine synthase activity
JS609_RS01350	COG0586	Pfam SNARE associated Golgi protein
JS609_RS01355	COG0688	phosphatidylethanolamine metabolic process
JS609_RS01365	COG2312	Erythromycin esterase
JS609_RS01370	COG2207	Transcriptional regulator
JS609_RS01375	COG1054	Belongs to the UPF0176 family
JS609_RS01380	COG1301	dicarboxylic acid transport
JS609_RS01385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JS609_RS01385	COG2190	(PTS) system
JS609_RS01385	COG1263	PTS System
JS609_RS01390	COG0363	glucosamine-6-phosphate deaminase activity
JS609_RS01395	COG2188	Transcriptional regulator
JS609_RS01405	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JS609_RS01410	COG0833	amino acid
JS609_RS01415	COG2040	homocysteine
JS609_RS01420	COG1115	amino acid carrier protein
JS609_RS01425	COG2066	Belongs to the glutaminase family
JS609_RS01430	COG4191	Histidine kinase
JS609_RS01435	COG0784	Response regulator, receiver
JS609_RS01440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JS609_RS01445	COG1012	belongs to the aldehyde dehydrogenase family
JS609_RS01450	COG2271	Major facilitator Superfamily
JS609_RS01455	COG4948	Mandelate Racemase Muconate Lactonizing
JS609_RS01460	COG2186	Transcriptional regulator
JS609_RS01465	COG2721	sulfolactate sulfo-lyase activity
JS609_RS01470	COG3173	Aminoglycoside phosphotransferase
JS609_RS01480	COG0697	spore germination
JS609_RS01485	COG0745	RESPONSE REGULATOR receiver
JS609_RS01490	COG2205	protein histidine kinase activity
JS609_RS01495	COG1131	(ABC) transporter
JS609_RS01515	COG3773	Cell wall hydrolase
JS609_RS01520	COG2304	oxidoreductase activity
JS609_RS01530	COG3540	Alkaline phosphatase
JS609_RS01535	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JS609_RS01540	COG0805	protein transport
JS609_RS01545	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
JS609_RS01550	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JS609_RS01555	COG0477	Major facilitator Superfamily
JS609_RS01560	COG1309	transcriptional regulator
JS609_RS01565	COG0252	asparaginase activity
JS609_RS01570	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
JS609_RS01575	COG1714	RDD family
JS609_RS01580	COG1405	negative regulation of cell septum assembly
JS609_RS01580	COG3012	SEC-C Motif Domain Protein
JS609_RS01585	COG3290	protein histidine kinase activity
JS609_RS01590	COG3279	Response regulator of the LytR AlgR family
JS609_RS01595	COG4555	ABC transporter
JS609_RS01600	COG1668	transmembrane transport
JS609_RS01605	COG0667	Aldo Keto reductase
JS609_RS01620	COG1595	DNA-templated transcription, initiation
JS609_RS01625	COG1595	DNA-templated transcription, initiation
JS609_RS01630	COG1876	peptidase activity
JS609_RS01635	COG0457	Tetratricopeptide repeat
JS609_RS01640	COG1028	Short-chain dehydrogenase reductase Sdr
JS609_RS01645	COG0366	Alpha amylase catalytic
JS609_RS01650	COG0803	Belongs to the bacterial solute-binding protein 9 family
JS609_RS01655	COG1121	(ABC) transporter
JS609_RS01660	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JS609_RS01665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JS609_RS01670	COG2310	stress, protein
JS609_RS01675	COG2310	stress, protein
JS609_RS01680	COG2310	stress, protein
JS609_RS01685	COG0861	Integral membrane protein TerC family
JS609_RS01695	COG3853	Toxic anion resistance protein (TelA)
JS609_RS01700	COG0477	Major facilitator Superfamily
JS609_RS01705	COG2814	Major facilitator Superfamily
JS609_RS01710	COG0640	Transcriptional regulator
JS609_RS01715	COG0517	IMP dehydrogenase activity
JS609_RS01715	COG4175	Glycine betaine
JS609_RS01720	COG4176	ABC-type proline glycine betaine transport system permease component
JS609_RS01725	COG2113	Glycine betaine
JS609_RS01730	COG1473	amidohydrolase
JS609_RS01735	COG1288	antiporter activity
JS609_RS01745	COG0366	Alpha amylase catalytic
JS609_RS01750	COG0039	L-malate dehydrogenase activity
JS609_RS01755	COG1620	l-lactate permease
JS609_RS01760	COG2814	Major facilitator Superfamily
JS609_RS01765	COG1846	Transcriptional regulator
JS609_RS01770	COG1280	lysine exporter protein (LysE YggA)
JS609_RS01775	COG3403	YqcI/YcgG family
JS609_RS01780	COG1113	amino acid transport
JS609_RS01785	COG3665	Urea carboxylase-associated protein
JS609_RS01790	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JS609_RS01795	COG1660	Displays ATPase and GTPase activities
JS609_RS01800	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JS609_RS01805	COG2226	methyltransferase
JS609_RS01810	COG0583	DNA-binding transcription factor activity
JS609_RS01815	COG3458	cephalosporin-C deacetylase activity
JS609_RS01820	COG3541	Predicted nucleotidyltransferase
JS609_RS01825	COG0506	proline dehydrogenase activity
JS609_RS01830	COG1012	belongs to the aldehyde dehydrogenase family
JS609_RS01835	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JS609_RS01840	COG2508	Transcriptional regulator
JS609_RS01845	COG3689	TIGRFAM TIGR03943 family protein
JS609_RS01850	COG0701	Predicted permease
JS609_RS01855	COG2267	carboxylic ester hydrolase activity
JS609_RS01860	COG0492	ferredoxin-NADP+ reductase activity
JS609_RS01865	COG1587	Uroporphyrinogen-III synthase
JS609_RS01865	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JS609_RS01870	COG2146	nitrite reductase [NAD(P)H] activity
JS609_RS01875	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JS609_RS01880	COG0243	molybdopterin cofactor binding
JS609_RS01885	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JS609_RS01890	COG2223	nitrite transmembrane transporter activity
JS609_RS01895	COG1469	GTP cyclohydrolase I activity
JS609_RS01900	COG1376	ErfK ybiS ycfS ynhG family protein
JS609_RS01915	COG0523	cobalamin synthesis protein
JS609_RS01920	COG0765	amino acid transport
JS609_RS01925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JS609_RS01935	COG1714	RDD family
JS609_RS01945	COG1846	Transcriptional regulator
JS609_RS01955	COG3842	ATPase activity
JS609_RS01960	COG2723	6-phospho-beta-galactosidase activity
JS609_RS01970	COG3209	COG3209 Rhs family protein
JS609_RS01975	COG0840	transmembrane signaling receptor activity
JS609_RS01975	COG3290	protein histidine kinase activity
JS609_RS01980	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
JS609_RS01985	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
JS609_RS01990	COG1733	regulation of RNA biosynthetic process
JS609_RS01995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JS609_RS02015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JS609_RS02025	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
JS609_RS02030	COG2814	Major facilitator Superfamily
JS609_RS02040	COG0697	spore germination
JS609_RS02045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JS609_RS02055	COG2364	Membrane
JS609_RS02060	COG1126	abc transporter atp-binding protein
JS609_RS02065	COG0765	amino acid transport
JS609_RS02070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JS609_RS02075	COG0583	DNA-binding transcription factor activity
JS609_RS02080	COG0163	prenyltransferase activity
JS609_RS02085	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
JS609_RS02100	COG0596	Alpha beta hydrolase
JS609_RS02105	COG3104	oligopeptide transport
JS609_RS02110	COG5434	Belongs to the glycosyl hydrolase 28 family
JS609_RS02120	COG0697	spore germination
JS609_RS02130	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
JS609_RS02135	COG1136	(ABC) transporter
JS609_RS02140	COG0577	efflux transmembrane transporter activity
JS609_RS02145	COG0745	RESPONSE REGULATOR receiver
JS609_RS02150	COG5002	protein histidine kinase activity
JS609_RS02150	COG3850	Histidine kinase
JS609_RS02155	COG0457	Tetratricopeptide repeat
JS609_RS02175	COG0527	aspartate kinase activity
JS609_RS02180	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JS609_RS02185	COG4605	iron ion homeostasis
JS609_RS02190	COG4604	ABC transporter, ATP-binding protein
JS609_RS02195	COG4607	ABC-type enterochelin transport system periplasmic component
JS609_RS02200	COG2814	Major facilitator Superfamily
JS609_RS02205	COG1309	transcriptional regulator
JS609_RS02210	COG0778	Nitroreductase
JS609_RS02215	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
JS609_RS02220	COG0640	Transcriptional regulator
JS609_RS02225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JS609_RS02230	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JS609_RS02235	COG1012	belongs to the aldehyde dehydrogenase family
JS609_RS02240	COG4975	Glucose uptake
JS609_RS02245	COG1028	Short-chain dehydrogenase reductase Sdr
JS609_RS02250	COG4549	nuclear export factor GLE1
JS609_RS02255	COG1276	copper resistance
JS609_RS02255	COG2372	response to copper ion
JS609_RS02260	COG1349	DNA-binding transcription factor activity
JS609_RS02270	COG2213	PTS system mannitol-specific
JS609_RS02275	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JS609_RS02280	COG0246	Mannitol dehydrogenase
JS609_RS02285	COG0473	3-isopropylmalate dehydrogenase activity
JS609_RS02290	COG0681	Belongs to the peptidase S26 family
JS609_RS02295	COG0412	Dienelactone hydrolase
JS609_RS02300	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JS609_RS02310	COG0561	phosphatase activity
JS609_RS02315	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JS609_RS02320	COG1914	H( )-stimulated, divalent metal cation uptake system
JS609_RS02325	COG4336	lyase activity
JS609_RS02330	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JS609_RS02335	COG1984	allophanate hydrolase subunit 2
JS609_RS02340	COG1414	Transcriptional regulator
JS609_RS02345	COG2755	lipolytic protein G-D-S-L family
JS609_RS02355	COG2329	Antibiotic biosynthesis monooxygenase
JS609_RS02360	COG0768	penicillin binding
JS609_RS02365	COG4989	oxidoreductase activity
JS609_RS02370	COG3711	transcriptional antiterminator
JS609_RS02375	COG0318	PFAM AMP-dependent synthetase and ligase
JS609_RS02380	COG2226	methyltransferase
JS609_RS02385	COG1028	Short-chain dehydrogenase reductase Sdr
JS609_RS02390	COG1917	Cupin 2, conserved barrel domain protein
JS609_RS02395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JS609_RS02400	COG3871	stress protein (general stress protein 26)
JS609_RS02410	COG2814	Major facilitator Superfamily
JS609_RS02415	COG1522	sequence-specific DNA binding
JS609_RS02420	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JS609_RS02420	COG0551	DNA topoisomerase type I activity
JS609_RS02425	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
JS609_RS02430	COG3706	GGDEF domain
JS609_RS02435	COG5298	Protein conserved in bacteria
JS609_RS02440	COG1215	transferase activity, transferring glycosyl groups
JS609_RS02450	COG0531	amino acid
JS609_RS02455	COG0494	nUDIX hydrolase
JS609_RS02470	COG1914	H( )-stimulated, divalent metal cation uptake system
JS609_RS02475	COG2261	transglycosylase associated protein
JS609_RS02480	COG4876	unkown
JS609_RS02485	COG2217	Heavy metal translocating P-type atpase
JS609_RS02490	COG3729	General stress protein
JS609_RS02495	COG0662	Cupin 2, conserved barrel domain protein
JS609_RS02500	COG2329	Antibiotic biosynthesis monooxygenase
JS609_RS02505	COG3546	catalase activity
JS609_RS02510	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JS609_RS02515	COG3290	protein histidine kinase activity
JS609_RS02520	COG4565	transcriptional regulatory protein
JS609_RS02525	COG1301	dicarboxylic acid transport
JS609_RS02530	COG0628	permease
JS609_RS02535	COG1131	(ABC) transporter
JS609_RS02540	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
JS609_RS02550	COG1960	acyl-CoA dehydrogenase activity
JS609_RS02565	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JS609_RS02570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JS609_RS02575	COG1181	Belongs to the D-alanine--D-alanine ligase family
JS609_RS02580	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JS609_RS02585	COG0513	Belongs to the DEAD box helicase family
JS609_RS02590	COG3402	PFAM membrane-flanked domain
JS609_RS02595	COG3428	Bacterial PH domain
JS609_RS02600	COG0705	Rhomboid family
JS609_RS02605	COG0736	holo-[acyl-carrier-protein] synthase activity
JS609_RS02610	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
JS609_RS02615	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JS609_RS02620	COG0864	Transcriptional regulator
JS609_RS02625	COG2337	Toxic component of a toxin-antitoxin (TA) module
JS609_RS02630	COG1366	Belongs to the anti-sigma-factor antagonist family
JS609_RS02635	COG1366	Belongs to the anti-sigma-factor antagonist family
JS609_RS02640	COG2172	sigma factor antagonist activity
JS609_RS02645	COG2208	phosphoserine phosphatase activity
JS609_RS02650	COG1366	Belongs to the anti-sigma-factor antagonist family
JS609_RS02655	COG2172	sigma factor antagonist activity
JS609_RS02660	COG1191	sigma factor activity
JS609_RS02665	COG2208	phosphoserine phosphatase activity
JS609_RS02670	COG2183	response to ionizing radiation
JS609_RS02680	COG3091	SprT-like family
JS609_RS02720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JS609_RS02750	COG3764	Sortase (surface protein transpeptidase)
JS609_RS02755	COG1476	TRANSCRIPTIONal
JS609_RS02765	COG3239	Fatty acid desaturase
JS609_RS02770	COG1278	Cold shock
JS609_RS02775	COG1329	Transcriptional regulator
JS609_RS02780	COG0697	spore germination
JS609_RS02785	COG2207	Transcriptional regulator
JS609_RS02785	COG1917	Cupin 2, conserved barrel domain protein
JS609_RS02790	COG0697	spore germination
JS609_RS02795	COG3708	Transcriptional regulator
JS609_RS02795	COG2207	Transcriptional regulator
JS609_RS02800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JS609_RS02805	COG0477	Major facilitator Superfamily
JS609_RS02815	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
JS609_RS02855	COG1309	transcriptional regulator
JS609_RS02860	COG0697	spore germination
JS609_RS02865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JS609_RS02870	COG2030	dehydratase
JS609_RS02875	COG3545	Serine hydrolase
JS609_RS02885	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JS609_RS02890	COG1733	regulation of RNA biosynthetic process
JS609_RS02895	COG2249	NAD(P)H dehydrogenase (quinone) activity
JS609_RS02905	COG1309	transcriptional regulator
JS609_RS02910	COG0640	Transcriptional regulator
JS609_RS02915	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JS609_RS02925	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JS609_RS02930	COG0697	spore germination
JS609_RS02935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JS609_RS02940	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JS609_RS02945	COG0640	Transcriptional regulator
JS609_RS02950	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JS609_RS02965	COG4585	Histidine kinase
JS609_RS02970	COG2197	response regulator
JS609_RS02975	COG2409	Drug exporters of the RND superfamily
JS609_RS02980	COG0596	Alpha beta hydrolase
JS609_RS02985	COG1811	Na channel or pump
JS609_RS02990	COG0789	Transcriptional regulator
JS609_RS02990	COG4978	Transcriptional regulator
JS609_RS02995	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JS609_RS03000	COG0778	Nitroreductase
JS609_RS03005	COG0346	lactoylglutathione lyase activity
JS609_RS03010	COG2259	Doxx family
JS609_RS03015	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JS609_RS03035	COG2323	membrane
JS609_RS03040	COG2323	membrane
JS609_RS03045	COG0071	Belongs to the small heat shock protein (HSP20) family
JS609_RS03060	COG1309	transcriptional regulator
JS609_RS03070	COG0456	acetyltransferase
JS609_RS03075	COG0488	(ABC) transporter
JS609_RS03080	COG1113	amino acid transport
JS609_RS03085	COG2318	DinB family
JS609_RS03090	COG1846	Transcriptional regulator
JS609_RS03095	COG1033	growth of symbiont in host cell
JS609_RS03095	COG2409	Drug exporters of the RND superfamily
JS609_RS03100	COG0778	Nitroreductase
JS609_RS03105	COG1846	Transcriptional regulator
JS609_RS03110	COG2814	Major facilitator Superfamily
JS609_RS03115	COG0730	response to heat
JS609_RS03120	COG1802	Transcriptional regulator
JS609_RS03125	COG3858	chitin binding
JS609_RS03125	COG1388	LysM domain
JS609_RS03130	COG1819	glycosyl
JS609_RS03140	COG1785	Belongs to the alkaline phosphatase family
JS609_RS03145	COG5646	InterPro IPR014922
JS609_RS03155	COG0454	-acetyltransferase
JS609_RS03160	COG1078	dGTPase activity
JS609_RS03165	COG1388	LysM domain
JS609_RS03170	COG2814	Major facilitator Superfamily
JS609_RS03175	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JS609_RS03180	COG1447	Phosphotransferase system cellobiose-specific component IIA
JS609_RS03185	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JS609_RS03190	COG2723	6-phospho-beta-galactosidase activity
JS609_RS03195	COG2188	Transcriptional regulator
JS609_RS03200	COG1940	carbohydrate kinase activity
JS609_RS03205	COG1482	cell wall glycoprotein biosynthetic process
JS609_RS03210	COG4124	Belongs to the glycosyl hydrolase 26 family
JS609_RS03255	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
JS609_RS03260	COG0802	atpase or kinase
JS609_RS03265	COG1214	PFAM Peptidase M22, glycoprotease
JS609_RS03270	COG0456	acetyltransferase
JS609_RS03275	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JS609_RS03280	COG0488	(ABC) transporter
JS609_RS03285	COG0315	cyclic pyranopterin monophosphate synthase activity
JS609_RS03290	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JS609_RS03295	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JS609_RS03300	COG0805	protein transport
JS609_RS03310	COG1266	CAAX protease self-immunity
JS609_RS03320	COG0459	protein refolding
JS609_RS03325	COG1073	alpha beta
JS609_RS03330	COG0457	Tetratricopeptide repeat
JS609_RS03335	COG1063	alcohol dehydrogenase
JS609_RS03340	COG2211	Major facilitator Superfamily
JS609_RS03345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JS609_RS03350	COG1842	Phage shock protein A
JS609_RS03355	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JS609_RS03360	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
JS609_RS03365	COG4260	virion core protein, lumpy skin disease virus
JS609_RS03375	COG2814	Major facilitator Superfamily
JS609_RS03380	COG1063	alcohol dehydrogenase
JS609_RS03385	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JS609_RS03390	COG0823	Involved in the tonB-independent uptake of proteins
JS609_RS03405	COG2267	carboxylic ester hydrolase activity
JS609_RS03415	COG2132	Multicopper oxidase
JS609_RS03420	COG1113	amino acid transport
JS609_RS03430	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JS609_RS03435	COG0714	Associated with various cellular activities
JS609_RS03440	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
JS609_RS03445	COG1305	Transglutaminase-like
JS609_RS03450	COG0519	Catalyzes the synthesis of GMP from XMP
JS609_RS03450	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JS609_RS03465	COG2252	PERMEase
JS609_RS03470	COG3064	Membrane
JS609_RS03480	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
JS609_RS03490	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JS609_RS03495	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JS609_RS03500	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JS609_RS03505	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JS609_RS03510	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JS609_RS03515	COG0047	phosphoribosylformylglycinamidine synthase activity
JS609_RS03520	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JS609_RS03525	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JS609_RS03530	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JS609_RS03535	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JS609_RS03540	COG0138	bifunctional purine biosynthesis protein purh
JS609_RS03545	COG0151	Belongs to the GarS family
JS609_RS03550	COG1522	sequence-specific DNA binding
JS609_RS03555	COG0531	amino acid
JS609_RS03565	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JS609_RS03570	COG1470	cell adhesion involved in biofilm formation
JS609_RS03575	COG4496	protein, YerC YecD
JS609_RS03580	COG0069	glutamate synthase activity
JS609_RS03585	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
JS609_RS03590	COG0210	DNA helicase
JS609_RS03595	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JS609_RS03600	COG4851	CamS sex pheromone cAM373 precursor
JS609_RS03605	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JS609_RS03610	COG1285	pathogenesis
JS609_RS03615	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JS609_RS03620	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JS609_RS03625	COG0154	amidase activity
JS609_RS03630	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JS609_RS03640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JS609_RS03645	COG1597	lipid kinase activity
JS609_RS03650	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JS609_RS03665	COG0732	type I restriction modification DNA specificity domain
JS609_RS03670	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
JS609_RS03705	COG5444	nuclease activity
JS609_RS03715	COG3586	endonuclease activity
JS609_RS03725	COG0457	Tetratricopeptide repeat
JS609_RS03735	COG0217	transcriptional regulatory protein
JS609_RS03745	COG1309	transcriptional regulator
JS609_RS03750	COG3631	Ketosteroid isomerase-related protein
JS609_RS03770	COG3546	catalase activity
JS609_RS03775	COG0454	-acetyltransferase
JS609_RS03785	COG5578	integral membrane protein
JS609_RS03790	COG2972	Histidine kinase
JS609_RS03795	COG4753	response regulator
JS609_RS03795	COG2207	Transcriptional regulator
JS609_RS03800	COG1653	transport
JS609_RS03805	COG1175	transmembrane transport
JS609_RS03810	COG0395	ABC-type sugar transport system, permease component
JS609_RS03815	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
JS609_RS03820	COG2207	Transcriptional regulator
JS609_RS03825	COG2755	lipolytic protein G-D-S-L family
JS609_RS03835	COG5578	integral membrane protein
JS609_RS03840	COG3401	FG-GAP repeat protein
JS609_RS03845	COG3401	FG-GAP repeat protein
JS609_RS03850	COG2755	lipolytic protein G-D-S-L family
JS609_RS03855	COG1874	Beta-galactosidase
JS609_RS03865	COG1653	transport
JS609_RS03870	COG4209	transmembrane transport
JS609_RS03875	COG0395	ABC-type sugar transport system, permease component
JS609_RS03880	COG1486	melibiose metabolic process
JS609_RS03885	COG2323	membrane
JS609_RS03890	COG2329	Antibiotic biosynthesis monooxygenase
JS609_RS03895	COG0346	lactoylglutathione lyase activity
JS609_RS03910	COG5583	Uncharacterized small protein (DUF2292)
JS609_RS03915	COG0670	Belongs to the BI1 family
JS609_RS03920	COG0697	spore germination
JS609_RS03925	COG1846	Transcriptional regulator
JS609_RS03930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JS609_RS03940	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JS609_RS03940	COG2124	cytochrome p450
JS609_RS03945	COG1368	sulfuric ester hydrolase activity
JS609_RS03950	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JS609_RS03955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JS609_RS03960	COG1442	glycosyl transferase family 8
JS609_RS03965	COG1216	Glycosyl transferase, family 2
JS609_RS03970	COG1442	glycosyl transferase family 8
JS609_RS03975	COG2223	nitrite transmembrane transporter activity
JS609_RS03980	COG1011	Hydrolase
JS609_RS03985	COG0531	amino acid
JS609_RS03990	COG1012	belongs to the aldehyde dehydrogenase family
JS609_RS03995	COG0840	transmembrane signaling receptor activity
JS609_RS04000	COG0488	(ABC) transporter
JS609_RS04010	COG0789	Transcriptional regulator
JS609_RS04015	COG2814	Major facilitator Superfamily
JS609_RS04030	COG0488	(ABC) transporter
JS609_RS04035	COG0513	Belongs to the DEAD box helicase family
JS609_RS04040	COG0456	acetyltransferase
JS609_RS04045	COG2130	NADP-dependent
JS609_RS04050	COG1120	ATPase activity
JS609_RS04055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JS609_RS04060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JS609_RS04065	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JS609_RS04080	COG3866	Pectate lyase
JS609_RS04085	COG0471	metal ion transport
JS609_RS04090	COG3290	protein histidine kinase activity
JS609_RS04095	COG4565	transcriptional regulatory protein
JS609_RS04100	COG3181	Tripartite tricarboxylate transporter family receptor
JS609_RS04105	COG2851	Citrate transporter
JS609_RS04110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JS609_RS04115	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
JS609_RS04120	COG1254	Belongs to the acylphosphatase family
JS609_RS04125	COG2258	MOSC domain
JS609_RS04145	COG0024	Methionine aminopeptidase
JS609_RS04150	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JS609_RS04150	COG1263	PTS System
JS609_RS04155	COG1368	sulfuric ester hydrolase activity
JS609_RS04170	COG1115	amino acid carrier protein
JS609_RS04175	COG0531	amino acid
JS609_RS04190	COG0697	spore germination
JS609_RS04195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JS609_RS04195	COG1263	PTS System
JS609_RS04200	COG0366	Alpha amylase catalytic
JS609_RS04205	COG2188	Transcriptional regulator
JS609_RS04210	COG0778	Nitroreductase
JS609_RS04215	COG0737	Belongs to the 5'-nucleotidase family
JS609_RS04220	COG0693	protein deglycase activity
JS609_RS04225	COG2814	Major facilitator Superfamily
JS609_RS04230	COG4840	Belongs to the UPF0435 family
JS609_RS04235	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JS609_RS04240	COG4980	gas vesicle protein
JS609_RS04245	COG1295	ribonuclease BN
JS609_RS04250	COG0477	Major facilitator Superfamily
JS609_RS04255	COG0387	Pfam Sodium calcium exchanger
JS609_RS04265	COG0668	transmembrane transport
JS609_RS04270	COG0535	radical SAM domain protein
JS609_RS04280	COG0726	polysaccharide deacetylase
JS609_RS04285	COG2084	Dehydrogenase
JS609_RS04290	COG0598	Magnesium transport protein CorA
JS609_RS04295	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JS609_RS04300	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JS609_RS04310	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JS609_RS04315	COG4637	Psort location Cytoplasmic, score
JS609_RS04325	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JS609_RS04330	COG0022	dehydrogenase e1 component
JS609_RS04335	COG0508	dehydrogenase complex catalyzes the overall conversion of
JS609_RS04340	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JS609_RS04345	COG3284	Transcriptional regulator
JS609_RS04355	COG1742	UPF0060 membrane protein
JS609_RS04375	COG4842	Belongs to the WXG100 family
JS609_RS04380	COG1486	melibiose metabolic process
JS609_RS04385	COG1737	Transcriptional regulator
JS609_RS04390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JS609_RS04390	COG1263	PTS System
JS609_RS04395	COG1132	(ABC) transporter
JS609_RS04400	COG1132	(ABC) transporter
JS609_RS04405	COG2259	Doxx family
JS609_RS04410	COG2514	catechol 2,3-dioxygenase activity
JS609_RS04415	COG4585	Histidine kinase
JS609_RS04420	COG2197	response regulator
JS609_RS04425	COG1131	(ABC) transporter
JS609_RS04430	COG1511	domain protein
JS609_RS04430	COG0842	Transport permease protein
JS609_RS04435	COG0842	Transport permease protein
JS609_RS04440	COG1695	Transcriptional regulator
JS609_RS04445	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
JS609_RS04450	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
JS609_RS04455	COG2318	DinB family
JS609_RS04460	COG2814	Major facilitator Superfamily
JS609_RS04465	COG1846	Transcriptional regulator
JS609_RS04470	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JS609_RS04470	COG0392	lysyltransferase activity
JS609_RS04475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JS609_RS04480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JS609_RS04490	COG0384	phenazine biosynthesis protein PhzF
JS609_RS04495	COG0778	Nitroreductase
JS609_RS04510	COG1090	epimerase
JS609_RS04515	COG2137	regulation of response to DNA damage stimulus
JS609_RS04525	COG2814	Major facilitator Superfamily
JS609_RS04540	COG3103	Sh3 type 3 domain protein
JS609_RS04545	COG5658	integral membrane protein
JS609_RS04550	COG0596	Alpha beta hydrolase
JS609_RS04555	COG0463	Glycosyl transferase, family 2
JS609_RS04560	COG4485	Bacterial membrane protein, YfhO
JS609_RS04565	COG1988	membrane-bound metal-dependent
JS609_RS04570	COG1194	a g-specific adenine glycosylase
JS609_RS04580	COG1028	Short-chain dehydrogenase reductase Sdr
JS609_RS04595	COG3557	Belongs to the UPF0374 family
JS609_RS04600	COG1132	(ABC) transporter
JS609_RS04605	COG4129	membrane
JS609_RS04610	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JS609_RS04615	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JS609_RS04620	COG0735	belongs to the Fur family
JS609_RS04730	COG4326	sporulation control protein
JS609_RS04750	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JS609_RS04765	COG0753	catalase activity
JS609_RS04770	COG1116	anion transmembrane transporter activity
JS609_RS04775	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JS609_RS04780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JS609_RS04785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JS609_RS04795	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JS609_RS04805	COG1476	TRANSCRIPTIONal
JS609_RS04815	COG3382	B3 4 domain protein
JS609_RS04820	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JS609_RS04830	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JS609_RS04835	COG0789	Transcriptional regulator
JS609_RS04840	COG1664	Polymer-forming cytoskeletal
JS609_RS04845	COG1664	Polymer-forming cytoskeletal
JS609_RS04850	COG2766	serine protein kinase
JS609_RS04855	COG2718	Belongs to the UPF0229 family
JS609_RS04860	COG1846	Transcriptional regulator
JS609_RS04865	COG1566	PFAM secretion protein HlyD family protein
JS609_RS04870	COG2814	Major facilitator Superfamily
JS609_RS04875	COG0655	NAD(P)H dehydrogenase (quinone) activity
JS609_RS04895	COG1725	Transcriptional regulator
JS609_RS04900	COG1131	(ABC) transporter
JS609_RS04905	COG1131	(ABC) transporter
JS609_RS04910	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
JS609_RS04915	COG1278	Cold shock
JS609_RS04920	COG1464	Belongs to the NlpA lipoprotein family
JS609_RS04925	COG3706	GGDEF domain
JS609_RS04930	COG1823	symporter activity
JS609_RS04950	COG5577	PFAM Coat F domain
JS609_RS04960	COG3764	Sortase (surface protein transpeptidase)
JS609_RS04965	COG0564	pseudouridine synthase activity
JS609_RS04975	COG0517	IMP dehydrogenase activity
JS609_RS04980	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JS609_RS04985	COG3153	acetyltransferase
JS609_RS04985	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JS609_RS04990	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JS609_RS04995	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
JS609_RS05000	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JS609_RS05005	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JS609_RS05010	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JS609_RS05015	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JS609_RS05020	COG4585	Histidine kinase
JS609_RS05020	COG2203	Gaf domain
JS609_RS05025	COG2197	response regulator
JS609_RS05030	COG0431	NADPH-dependent FMN reductase
JS609_RS05045	COG1388	LysM domain
JS609_RS05045	COG0791	NLP P60 protein
JS609_RS05050	COG1959	2 iron, 2 sulfur cluster binding
JS609_RS05055	COG0668	transmembrane transport
JS609_RS05060	COG2719	SpoVR family
JS609_RS05065	COG1785	Belongs to the alkaline phosphatase family
JS609_RS05070	COG1388	LysM domain
JS609_RS05070	COG0791	NLP P60 protein
JS609_RS05075	COG0583	DNA-binding transcription factor activity
JS609_RS05080	COG0372	Belongs to the citrate synthase family
JS609_RS05085	COG1028	Short-chain dehydrogenase reductase Sdr
JS609_RS05090	COG0531	amino acid
JS609_RS05095	COG0733	neurotransmitter:sodium symporter activity
JS609_RS05100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JS609_RS05105	COG0456	acetyltransferase
JS609_RS05120	COG1595	DNA-templated transcription, initiation
JS609_RS05125	COG0667	Aldo Keto reductase
JS609_RS05130	COG0204	Acyl-transferase
JS609_RS05135	COG1253	flavin adenine dinucleotide binding
JS609_RS05140	COG0789	Transcriptional regulator
JS609_RS05145	COG0436	Aminotransferase
JS609_RS05150	COG1253	flavin adenine dinucleotide binding
JS609_RS05155	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JS609_RS05160	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JS609_RS05165	COG0584	glycerophosphoryl diester phosphodiesterase
JS609_RS05175	COG0668	transmembrane transport
JS609_RS05180	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JS609_RS05185	COG0726	polysaccharide deacetylase
JS609_RS05190	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JS609_RS05195	COG1757	Na H antiporter
JS609_RS05200	COG0589	response to stress
JS609_RS05210	COG1132	(ABC) transporter
JS609_RS05215	COG1132	(ABC) transporter
JS609_RS05220	COG0702	epimerase
JS609_RS05240	COG0189	ligase activity
JS609_RS05245	COG0189	ligase activity
JS609_RS05255	COG3679	Belongs to the UPF0342 family
JS609_RS05260	COG4335	DNA alkylation repair
JS609_RS05265	COG0561	phosphatase activity
JS609_RS05270	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JS609_RS05275	COG0475	glutathione-regulated potassium exporter activity
JS609_RS05280	COG0490	domain, Protein
JS609_RS05290	COG1024	Enoyl-CoA hydratase
JS609_RS05300	COG4152	abc transporter atp-binding protein
JS609_RS05305	COG1668	transmembrane transport
JS609_RS05310	COG0420	3'-5' exonuclease activity
JS609_RS05315	COG4717	serine-type aminopeptidase activity
JS609_RS05320	COG3481	metal-dependent phosphohydrolase, HD sub domain
JS609_RS05330	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JS609_RS05360	COG1846	Transcriptional regulator
JS609_RS05365	COG4980	gas vesicle protein
JS609_RS05380	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JS609_RS05385	COG0537	adenosine 5'-monophosphoramidase activity
JS609_RS05390	COG1131	(ABC) transporter
JS609_RS05395	COG4473	ABC transporter
JS609_RS05405	COG1473	amidohydrolase
JS609_RS05410	COG3069	C4-dicarboxylate transmembrane transporter activity
JS609_RS05420	COG2329	Antibiotic biosynthesis monooxygenase
JS609_RS05425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JS609_RS05430	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JS609_RS05435	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JS609_RS05440	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JS609_RS05445	COG1309	transcriptional regulator
JS609_RS05450	COG1511	domain protein
JS609_RS05455	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JS609_RS05460	COG4377	Putative membrane peptidase family (DUF2324)
JS609_RS05470	COG1363	Peptidase, m42
JS609_RS05475	COG4405	Protein conserved in bacteria
JS609_RS05480	COG1301	dicarboxylic acid transport
JS609_RS05490	COG1234	tRNA 3'-trailer cleavage
JS609_RS05495	COG0095	Lipoate-protein ligase
JS609_RS05500	COG0702	epimerase
JS609_RS05505	COG0318	PFAM AMP-dependent synthetase and ligase
JS609_RS05515	COG0501	Belongs to the peptidase M48B family
JS609_RS05525	COG0456	acetyltransferase
JS609_RS05530	COG0604	alcohol dehydrogenase
JS609_RS05535	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JS609_RS05540	COG0406	alpha-ribazole phosphatase activity
JS609_RS05545	COG0183	Belongs to the thiolase family
JS609_RS05550	COG0318	PFAM AMP-dependent synthetase and ligase
JS609_RS05555	COG1268	BioY protein
JS609_RS05560	COG0840	transmembrane signaling receptor activity
JS609_RS05565	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JS609_RS05565	COG0723	plastoquinol--plastocyanin reductase activity
JS609_RS05570	COG1028	Short-chain dehydrogenase reductase Sdr
JS609_RS05580	COG4903	ComK protein
JS609_RS05585	COG1028	Short-chain dehydrogenase reductase Sdr
JS609_RS05595	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JS609_RS05610	COG0398	Pfam SNARE associated Golgi protein
JS609_RS05615	COG0681	Belongs to the peptidase S26 family
JS609_RS05620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JS609_RS05625	COG1846	Transcriptional regulator
JS609_RS05630	COG0738	Major facilitator superfamily
JS609_RS05635	COG0673	inositol 2-dehydrogenase activity
JS609_RS05640	COG0561	phosphatase activity
JS609_RS05645	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JS609_RS05650	COG1609	Transcriptional regulator
JS609_RS05655	COG3180	Ammonia monooxygenase
JS609_RS05660	COG2814	Major facilitator Superfamily
JS609_RS05660	COG0477	Major facilitator Superfamily
JS609_RS05665	COG4533	DNA binding
JS609_RS05675	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
JS609_RS05680	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
JS609_RS05685	COG1074	ATP-dependent DNA helicase activity
JS609_RS05690	COG0420	3'-5' exonuclease activity
JS609_RS05695	COG0419	ATPase involved in DNA repair
JS609_RS05700	COG1403	HNH endonuclease
JS609_RS05740	COG5337	Spore coat protein CotH
JS609_RS05745	COG0179	Fumarylacetoacetate (FAA) hydrolase
JS609_RS05755	COG1404	Belongs to the peptidase S8 family
JS609_RS05765	COG0367	asparagine synthase
JS609_RS05770	COG2318	DinB family
JS609_RS05775	COG1562	ergosterol biosynthetic process
JS609_RS05780	COG0534	Mate efflux family protein
JS609_RS05785	COG2207	Transcriptional regulator
JS609_RS05785	COG1917	Cupin 2, conserved barrel domain protein
JS609_RS05790	COG1609	Transcriptional regulator
JS609_RS05795	COG0673	inositol 2-dehydrogenase activity
JS609_RS05800	COG2318	DinB family
JS609_RS05810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JS609_RS05815	COG1357	PFAM Pentapeptide repeats (8 copies)
JS609_RS05820	COG2267	carboxylic ester hydrolase activity
JS609_RS05825	COG0529	Catalyzes the synthesis of activated sulfate
JS609_RS05830	COG2046	Belongs to the sulfate adenylyltransferase family
JS609_RS05835	COG0175	sulfate reduction
JS609_RS05840	COG2045	Belongs to the ComB family
JS609_RS05845	COG1809	phosphosulfolactate synthase activity
JS609_RS05850	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JS609_RS05855	COG4948	Mandelate Racemase Muconate Lactonizing
JS609_RS05860	COG2814	Major facilitator Superfamily
JS609_RS05865	COG0454	-acetyltransferase
JS609_RS05870	COG2153	protein acetylation
JS609_RS05875	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JS609_RS05875	COG0646	methionine synthase
JS609_RS05880	COG1666	GTP binding
JS609_RS05885	COG2996	Protein conserved in bacteria
JS609_RS05905	COG1695	Transcriptional regulator
JS609_RS05920	COG3227	Zinc metalloprotease (Elastase)
JS609_RS05925	COG1307	EDD domain protein, DegV family
JS609_RS05930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JS609_RS05950	COG0561	phosphatase activity
JS609_RS05955	COG1073	alpha beta
JS609_RS05960	COG2151	metal-sulfur cluster biosynthetic enzyme
JS609_RS05970	COG0277	FAD linked oxidase domain protein
JS609_RS05975	COG2271	Major facilitator Superfamily
JS609_RS05980	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JS609_RS05985	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JS609_RS05995	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JS609_RS06000	COG0505	Belongs to the CarA family
JS609_RS06005	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JS609_RS06010	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JS609_RS06025	COG2267	carboxylic ester hydrolase activity
JS609_RS06035	COG1744	ABC transporter substrate-binding protein PnrA-like
JS609_RS06050	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JS609_RS06055	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JS609_RS06060	COG5504	Zn-dependent protease
JS609_RS06065	COG0444	Belongs to the ABC transporter superfamily
JS609_RS06070	COG4608	Belongs to the ABC transporter superfamily
JS609_RS06080	COG0601	transmembrane transport
JS609_RS06085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JS609_RS06095	COG0180	Tryptophanyl-tRNA synthetase
JS609_RS06100	COG4166	transmembrane transport
JS609_RS06105	COG0601	transmembrane transport
JS609_RS06110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JS609_RS06115	COG0444	Belongs to the ABC transporter superfamily
JS609_RS06120	COG4608	Belongs to the ABC transporter superfamily
JS609_RS06125	COG2814	Major facilitator Superfamily
JS609_RS06130	COG0456	acetyltransferase
JS609_RS06135	COG1393	Belongs to the ArsC family
JS609_RS06140	COG0861	Integral membrane protein TerC family
JS609_RS06150	COG4862	establishment of competence for transformation
JS609_RS06160	COG4469	Competence protein
JS609_RS06165	COG1164	Oligoendopeptidase f
JS609_RS06175	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JS609_RS06180	COG2346	COG2346, Truncated hemoglobins
JS609_RS06185	COG0741	lytic transglycosylase activity
JS609_RS06190	COG4116	CYTH
JS609_RS06200	COG2357	RelA SpoT domain protein
JS609_RS06205	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JS609_RS06210	COG0564	pseudouridine synthase activity
JS609_RS06215	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JS609_RS06220	COG0569	domain protein
JS609_RS06220	COG0475	glutathione-regulated potassium exporter activity
JS609_RS06225	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JS609_RS06230	COG0352	thiamine-phosphate diphosphorylase activity
JS609_RS06235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JS609_RS06240	COG2104	thiamine diphosphate biosynthetic process
JS609_RS06245	COG2022	thiamine diphosphate biosynthetic process
JS609_RS06250	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JS609_RS06255	COG0351	phosphomethylpyrimidine kinase
JS609_RS06260	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JS609_RS06315	COG0210	DNA helicase
JS609_RS06325	COG2153	protein acetylation
JS609_RS06330	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JS609_RS06335	COG2382	esterase
JS609_RS06340	COG0626	cystathionine gamma-synthase activity
JS609_RS06345	COG0626	cystathionine gamma-synthase activity
JS609_RS06350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JS609_RS06355	COG5505	Protein of unknown function (DUF819)
JS609_RS06370	COG5444	nuclease activity
JS609_RS06455	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
JS609_RS06460	COG1028	Short-chain dehydrogenase reductase Sdr
JS609_RS06470	COG3711	transcriptional antiterminator
JS609_RS06470	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JS609_RS06475	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JS609_RS06475	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JS609_RS06475	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JS609_RS06480	COG1482	cell wall glycoprotein biosynthetic process
JS609_RS06490	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JS609_RS06500	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JS609_RS06515	COG0109	protoheme IX farnesyltransferase activity
JS609_RS06525	COG0726	polysaccharide deacetylase
JS609_RS06540	COG5504	Zn-dependent protease
JS609_RS06545	COG2205	protein histidine kinase activity
JS609_RS06555	COG3383	formate dehydrogenase (NAD+) activity
JS609_RS06560	COG2427	Protein of unknown function (DUF1641)
JS609_RS06570	COG1051	belongs to the nudix hydrolase family
JS609_RS06580	COG2124	cytochrome p450
JS609_RS06585	COG1819	glycosyl
JS609_RS06595	COG1587	Uroporphyrinogen-III synthase
JS609_RS06600	COG0390	transport system, permease component
JS609_RS06605	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JS609_RS06610	COG0697	spore germination
JS609_RS06615	COG4297	protein containing double-stranded beta helix domain
JS609_RS06625	COG1252	NADH dehydrogenase
JS609_RS06630	COG1904	glucuronate isomerase
JS609_RS06635	COG2211	Major facilitator Superfamily
JS609_RS06640	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
JS609_RS06645	COG1063	alcohol dehydrogenase
JS609_RS06650	COG1312	Catalyzes the dehydration of D-mannonate
JS609_RS06655	COG1028	Short-chain dehydrogenase reductase Sdr
JS609_RS06660	COG2271	Major facilitator Superfamily
JS609_RS06665	COG1609	Transcriptional regulator
JS609_RS06670	COG0246	Mannitol dehydrogenase
JS609_RS06675	COG2721	sulfolactate sulfo-lyase activity
JS609_RS06680	COG0730	response to heat
JS609_RS06685	COG2318	DinB family
JS609_RS06690	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JS609_RS06695	COG0457	Tetratricopeptide repeat
JS609_RS06705	COG2350	Protein conserved in bacteria
JS609_RS06710	COG1388	LysM domain
JS609_RS06710	COG5632	N-Acetylmuramoyl-L-alanine amidase
JS609_RS06710	COG3409	Peptidoglycan-binding domain 1 protein
JS609_RS06725	COG3546	catalase activity
JS609_RS06730	COG2856	Zn peptidase
JS609_RS06735	COG1396	sequence-specific DNA binding
JS609_RS06745	COG1522	sequence-specific DNA binding
JS609_RS06750	COG1484	DNA-dependent DNA replication
JS609_RS06770	COG1595	DNA-templated transcription, initiation
JS609_RS06775	COG5484	DNA packaging
JS609_RS06775	COG3728	DNA packaging
JS609_RS06780	COG1783	phage Terminase large subunit
JS609_RS06785	COG5518	Phage portal protein
JS609_RS06790	COG0338	D12 class N6 adenine-specific DNA methyltransferase
JS609_RS06795	COG4653	Phage capsid family
JS609_RS06845	COG3953	SLT domain
JS609_RS06845	COG5412	phage tail tape measure protein
JS609_RS06850	COG1652	LysM domain
JS609_RS06855	COG4193	domain, Protein
JS609_RS06865	COG3628	GPW Gp25 family protein
JS609_RS06870	COG3299	homolog of phage Mu protein gp47
JS609_RS06875	COG3778	Protein conserved in bacteria
JS609_RS06915	COG3409	Peptidoglycan-binding domain 1 protein
JS609_RS06915	COG5632	N-Acetylmuramoyl-L-alanine amidase
JS609_RS06935	COG0306	phosphate transporter
JS609_RS06940	COG1392	Phosphate transport regulator
JS609_RS06945	COG0531	amino acid
JS609_RS06950	COG0346	lactoylglutathione lyase activity
JS609_RS06960	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JS609_RS06965	COG0463	Glycosyl transferase, family 2
JS609_RS06970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JS609_RS06975	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JS609_RS06980	COG2362	D-Aminopeptidase
JS609_RS06985	COG0601	transmembrane transport
JS609_RS06990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JS609_RS06995	COG0444	Belongs to the ABC transporter superfamily
JS609_RS07000	COG4166	transmembrane transport
JS609_RS07005	COG1619	proteins homologs of microcin C7 resistance protein MccF
JS609_RS07010	COG4948	Mandelate Racemase Muconate Lactonizing
JS609_RS07015	COG0791	NLP P60 protein
JS609_RS07020	COG4608	Belongs to the ABC transporter superfamily
JS609_RS07025	COG2706	6-phosphogluconolactonase activity
JS609_RS07030	COG1834	amidinotransferase
JS609_RS07035	COG1607	acyl-coa hydrolase
JS609_RS07040	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JS609_RS07040	COG1017	nitric oxide dioxygenase activity
JS609_RS07050	COG2323	membrane
JS609_RS07055	COG2318	DinB family
JS609_RS07065	COG2076	Multidrug Resistance protein
JS609_RS07070	COG2076	Multidrug Resistance protein
JS609_RS07075	COG0788	formyltetrahydrofolate deformylase activity
JS609_RS07080	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JS609_RS07085	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JS609_RS07090	COG1764	response to oxidative stress
JS609_RS07095	COG1846	Transcriptional regulator
JS609_RS07100	COG1764	response to oxidative stress
JS609_RS07110	COG0590	tRNA wobble adenosine to inosine editing
JS609_RS07120	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JS609_RS07125	COG1404	Belongs to the peptidase S8 family
JS609_RS07130	COG1366	Belongs to the anti-sigma-factor antagonist family
JS609_RS07135	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JS609_RS07140	COG1122	ATPase activity
JS609_RS07145	COG4721	ABC-type cobalt transport system, permease component
JS609_RS07155	COG0745	RESPONSE REGULATOR receiver
JS609_RS07160	COG5002	protein histidine kinase activity
JS609_RS07160	COG3850	Histidine kinase
JS609_RS07165	COG3212	peptidase
JS609_RS07170	COG3212	peptidase
JS609_RS07180	COG2239	Acts as a magnesium transporter
JS609_RS07185	COG0789	Transcriptional regulator
JS609_RS07200	COG1846	Transcriptional regulator
JS609_RS07210	COG0726	polysaccharide deacetylase
JS609_RS07215	COG1408	metallophosphoesterase
JS609_RS07225	COG0463	Glycosyl transferase, family 2
JS609_RS07230	COG3285	dna ligase
JS609_RS07230	COG1793	dna ligase
JS609_RS07235	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
JS609_RS07240	COG5001	Diguanylate cyclase
JS609_RS07240	COG3300	MHYT domain
JS609_RS07245	COG0586	Pfam SNARE associated Golgi protein
JS609_RS07250	COG0861	Integral membrane protein TerC family
JS609_RS07255	COG1191	sigma factor activity
JS609_RS07275	COG0501	Belongs to the peptidase M48B family
JS609_RS07280	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JS609_RS07295	COG3594	Acyltransferase
JS609_RS07300	COG5002	protein histidine kinase activity
JS609_RS07305	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JS609_RS07315	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
JS609_RS07320	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
JS609_RS07325	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JS609_RS07330	COG0436	Aminotransferase
JS609_RS07335	COG1850	ribulose-bisphosphate carboxylase activity
JS609_RS07340	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
JS609_RS07345	COG0235	Class ii aldolase
JS609_RS07350	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
JS609_RS07355	COG3339	Conserved Protein
JS609_RS07370	COG3852	Histidine kinase
JS609_RS07375	COG1846	Transcriptional regulator
JS609_RS07380	COG1360	Flagellar Motor Protein
JS609_RS07385	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JS609_RS07390	COG0542	response to heat
JS609_RS07395	COG3949	Membrane
JS609_RS07400	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JS609_RS07405	COG0720	synthase
JS609_RS07410	COG0602	queuosine metabolic process
JS609_RS07415	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JS609_RS07420	COG1733	regulation of RNA biosynthetic process
JS609_RS07425	COG1028	Short-chain dehydrogenase reductase Sdr
JS609_RS07430	COG4641	Protein conserved in bacteria
JS609_RS07430	COG1388	LysM domain
JS609_RS07435	COG1388	LysM domain
JS609_RS07440	COG3858	chitin binding
JS609_RS07450	COG4873	Protein conserved in bacteria
JS609_RS07460	COG3773	Cell wall hydrolase
JS609_RS07465	COG2244	polysaccharide biosynthetic process
JS609_RS07470	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JS609_RS07475	COG2217	Heavy metal translocating P-type atpase
JS609_RS07485	COG0006	proline dipeptidase activity
JS609_RS07490	COG1609	Transcriptional regulator
JS609_RS07495	COG3711	transcriptional antiterminator
JS609_RS07500	COG1263	PTS System
JS609_RS07500	COG2190	(PTS) system
JS609_RS07500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JS609_RS07505	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JS609_RS07510	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JS609_RS07520	COG1533	DNA photolyase activity
JS609_RS07525	COG0456	acetyltransferase
JS609_RS07530	COG0840	transmembrane signaling receptor activity
JS609_RS07535	COG2084	Dehydrogenase
JS609_RS07540	COG2340	Cysteine-rich secretory protein family
JS609_RS07545	COG0768	penicillin binding
JS609_RS07550	COG4191	Histidine kinase
JS609_RS07555	COG0436	Aminotransferase
JS609_RS07565	COG0835	chemotaxis
JS609_RS07565	COG0784	Response regulator, receiver
JS609_RS07575	COG2814	Major facilitator Superfamily
JS609_RS07580	COG1376	ErfK ybiS ycfS ynhG family protein
JS609_RS07585	COG1408	metallophosphoesterase
JS609_RS07590	COG1028	Short-chain dehydrogenase reductase Sdr
JS609_RS07595	COG2200	EAL domain
JS609_RS07600	COG4703	Protein of unknown function (DUF1797)
JS609_RS07605	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
JS609_RS07615	COG0517	IMP dehydrogenase activity
JS609_RS07620	COG0583	DNA-binding transcription factor activity
JS609_RS07625	COG0716	FMN binding
JS609_RS07635	COG0716	FMN binding
JS609_RS07640	COG2171	N-acyltransferase activity
JS609_RS07645	COG1473	amidohydrolase
JS609_RS07655	COG0668	transmembrane transport
JS609_RS07660	COG0450	alkyl hydroperoxide reductase
JS609_RS07665	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JS609_RS07680	COG0746	molybdenum cofactor guanylyltransferase activity
JS609_RS07685	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JS609_RS07690	COG0303	'Molybdopterin
JS609_RS07695	COG1763	Mo-molybdopterin cofactor biosynthetic process
JS609_RS07700	COG0314	molybdopterin synthase activity
JS609_RS07705	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
JS609_RS07710	COG1132	(ABC) transporter
JS609_RS07715	COG1132	(ABC) transporter
JS609_RS07725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JS609_RS07730	COG1136	(ABC) transporter
JS609_RS07735	COG0577	efflux transmembrane transporter activity
JS609_RS07740	COG1349	DNA-binding transcription factor activity
JS609_RS07745	COG1105	Belongs to the carbohydrate kinase PfkB family
JS609_RS07750	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JS609_RS07750	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JS609_RS07750	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JS609_RS07755	COG0681	Belongs to the peptidase S26 family
JS609_RS07765	COG0488	(ABC) transporter
JS609_RS07770	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JS609_RS07775	COG2309	aminopeptidase activity
JS609_RS07785	COG1077	Cell shape determining protein MreB Mrl
JS609_RS07790	COG2002	toxin-antitoxin pair type II binding
JS609_RS07795	COG3852	Histidine kinase
JS609_RS07800	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
JS609_RS07800	COG2105	PFAM AIG2 family protein
JS609_RS07805	COG0569	domain protein
JS609_RS07810	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JS609_RS07815	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JS609_RS07820	COG5503	Protein of unknown function (DUF1447)
JS609_RS07825	COG0561	phosphatase activity
JS609_RS07830	COG0242	peptide deformylase activity
JS609_RS07840	COG0497	DNA recombination
JS609_RS07845	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JS609_RS07850	COG0022	dehydrogenase e1 component
JS609_RS07855	COG0508	dehydrogenase complex catalyzes the overall conversion of
JS609_RS07860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JS609_RS07865	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JS609_RS07875	COG1982	Orn Lys Arg decarboxylase major
JS609_RS07880	COG4476	Belongs to the UPF0223 family
JS609_RS07885	COG4493	Belongs to the UPF0637 family
JS609_RS07895	COG0483	inositol monophosphate 1-phosphatase activity
JS609_RS07905	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JS609_RS07925	COG1595	DNA-templated transcription, initiation
JS609_RS07945	COG1217	gtp-binding protein TYPA
JS609_RS07955	COG4896	Protein conserved in bacteria
JS609_RS07965	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JS609_RS07970	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JS609_RS07975	COG2066	Belongs to the glutaminase family
JS609_RS07980	COG4838	Belongs to the UPF0358 family
JS609_RS07985	COG0772	Belongs to the SEDS family
JS609_RS07990	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JS609_RS07995	COG1612	heme a metabolic process
JS609_RS08000	COG0109	protoheme IX farnesyltransferase activity
JS609_RS08005	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JS609_RS08005	COG2010	Cytochrome c
JS609_RS08010	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JS609_RS08015	COG1845	cytochrome c oxidase, subunit III
JS609_RS08020	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JS609_RS08025	COG3336	cytochrome c oxidase
JS609_RS08035	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
JS609_RS08040	COG2340	Cysteine-rich secretory protein family
JS609_RS08055	COG3679	Belongs to the UPF0342 family
JS609_RS08060	COG4471	UPF0298 protein
JS609_RS08065	COG0742	ribosomal rna small subunit methyltransferase
JS609_RS08070	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JS609_RS08075	COG3314	Sporulation integral membrane protein YlbJ
JS609_RS08080	COG1752	Esterase of the alpha-beta hydrolase superfamily
JS609_RS08085	COG3480	Lon protease (S16) C-terminal proteolytic domain
JS609_RS08090	COG1323	Belongs to the UPF0348 family
JS609_RS08100	COG1399	metal-binding, possibly nucleic acid-binding protein
JS609_RS08115	COG0454	-acetyltransferase
JS609_RS08120	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JS609_RS08130	COG2001	Belongs to the MraZ family
JS609_RS08135	COG0275	rRNA processing
JS609_RS08140	COG4839	cell division protein FtsL
JS609_RS08145	COG0768	penicillin binding
JS609_RS08150	COG0768	penicillin binding
JS609_RS08155	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JS609_RS08160	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JS609_RS08165	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JS609_RS08170	COG0772	Belongs to the SEDS family
JS609_RS08175	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JS609_RS08180	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JS609_RS08185	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JS609_RS08190	COG3879	Bacterial protein of unknown function (DUF881)
JS609_RS08195	COG3879	Bacterial protein of unknown function (DUF881)
JS609_RS08200	COG3856	small basic protein
JS609_RS08205	COG0849	cell division
JS609_RS08210	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JS609_RS08215	COG1404	Belongs to the peptidase S8 family
JS609_RS08215	COG4412	M6 family metalloprotease domain protein
JS609_RS08225	COG1191	sigma factor activity
JS609_RS08230	COG1191	sigma factor activity
JS609_RS08235	COG1119	ATPase activity
JS609_RS08240	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JS609_RS08245	COG1873	PFAM PRC-barrel domain
JS609_RS08250	COG1496	oxidoreductase activity
JS609_RS08255	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JS609_RS08260	COG1799	cell septum assembly
JS609_RS08265	COG0762	integral membrane protein
JS609_RS08270	COG2302	S4 RNA-binding domain
JS609_RS08275	COG3599	regulation of cell shape
JS609_RS08280	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JS609_RS08285	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JS609_RS08290	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JS609_RS08295	COG0564	pseudouridine synthase activity
JS609_RS08300	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JS609_RS08305	COG2233	PERMEase
JS609_RS08310	COG0540	Belongs to the ATCase OTCase family
JS609_RS08315	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JS609_RS08320	COG0505	Belongs to the CarA family
JS609_RS08325	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JS609_RS08330	COG0543	2 iron, 2 sulfur cluster binding
JS609_RS08335	COG0167	dihydroorotate dehydrogenase activity
JS609_RS08340	COG0284	orotidine-5'-phosphate decarboxylase activity
JS609_RS08345	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JS609_RS08350	COG0175	sulfate reduction
JS609_RS08355	COG0306	phosphate transporter
JS609_RS08360	COG2046	Belongs to the sulfate adenylyltransferase family
JS609_RS08365	COG0529	Catalyzes the synthesis of activated sulfate
JS609_RS08370	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JS609_RS08375	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
JS609_RS08380	COG1648	precorrin-2 dehydrogenase activity
JS609_RS08385	COG1293	RNA-binding protein homologous to eukaryotic snRNP
JS609_RS08390	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JS609_RS08395	COG1561	YicC-like family, N-terminal region
JS609_RS08405	COG0194	GDP metabolic process
JS609_RS08410	COG1758	RNA polymerase activity
JS609_RS08415	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JS609_RS08420	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JS609_RS08425	COG0242	peptide deformylase activity
JS609_RS08430	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JS609_RS08435	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JS609_RS08435	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JS609_RS08440	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JS609_RS08445	COG0631	protein serine/threonine phosphatase activity
JS609_RS08450	COG2815	serine threonine protein kinase
JS609_RS08450	COG0515	serine threonine protein kinase
JS609_RS08455	COG1162	GTPase activity
JS609_RS08460	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JS609_RS08465	COG1564	THIamine pyrophosphokinase
JS609_RS08475	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JS609_RS08480	COG1302	Protein conserved in bacteria
JS609_RS08485	COG1461	Dihydroxyacetone kinase
JS609_RS08490	COG1760	l-serine dehydratase
JS609_RS08495	COG1760	l-serine dehydratase
JS609_RS08500	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JS609_RS08505	COG1349	DNA-binding transcription factor activity
JS609_RS08505	COG2050	protein possibly involved in aromatic compounds catabolism
JS609_RS08510	COG0416	fatty acid biosynthetic process
JS609_RS08515	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JS609_RS08520	COG1028	Short-chain dehydrogenase reductase Sdr
JS609_RS08530	COG0571	ribonuclease III activity
JS609_RS08535	COG1196	nuclear chromosome segregation
JS609_RS08540	COG0552	protein localization to endoplasmic reticulum
JS609_RS08550	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JS609_RS08555	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JS609_RS08560	COG0228	four-way junction DNA binding
JS609_RS08565	COG1837	Belongs to the UPF0109 family
JS609_RS08575	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JS609_RS08580	COG0336	Belongs to the RNA methyltransferase TrmD family
JS609_RS08585	COG0335	large ribosomal subunit rRNA binding
JS609_RS08590	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JS609_RS08595	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JS609_RS08605	COG2257	FlhB HrpN YscU SpaS Family
JS609_RS08610	COG0045	succinate-CoA ligase (ADP-forming) activity
JS609_RS08615	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JS609_RS08620	COG0758	DNA mediated transformation
JS609_RS08625	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JS609_RS08630	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JS609_RS08635	COG4974	Belongs to the 'phage' integrase family
JS609_RS08640	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JS609_RS08645	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JS609_RS08650	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JS609_RS08655	COG1815	bacterial-type flagellum-dependent cell motility
JS609_RS08660	COG1558	bacterial-type flagellum-dependent cell motility
JS609_RS08665	COG1677	Flagellar hook-basal body complex protein FliE
JS609_RS08670	COG1766	The M ring may be actively involved in energy transduction
JS609_RS08675	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JS609_RS08680	COG1317	bacterial-type flagellum organization
JS609_RS08685	COG1157	protein secretion by the type III secretion system
JS609_RS08690	COG2882	bacterial-type flagellum organization
JS609_RS08695	COG3334	PFAM MgtE intracellular
JS609_RS08700	COG3144	bacterial-type flagellum assembly
JS609_RS08705	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
JS609_RS08710	COG4786	Flagellar basal body rod
JS609_RS08715	COG1582	Flagellar protein (FlbD)
JS609_RS08720	COG1580	Controls the rotational direction of flagella during chemotaxis
JS609_RS08725	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JS609_RS08730	COG1776	CheC inhibitor of MCP methylation
JS609_RS08730	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JS609_RS08735	COG2201	protein-glutamate methylesterase activity
JS609_RS08740	COG3190	flagellar
JS609_RS08745	COG1338	Plays a role in the flagellum-specific transport system
JS609_RS08750	COG1987	bacterial-type flagellum assembly
JS609_RS08755	COG1684	flagellar biosynthetic protein fliR
JS609_RS08760	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JS609_RS08765	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JS609_RS08770	COG1419	protein localization to endoplasmic reticulum
JS609_RS08775	COG0455	bacterial-type flagellum organization
JS609_RS08780	COG2201	protein-glutamate methylesterase activity
JS609_RS08785	COG0643	Histidine kinase
JS609_RS08785	COG2198	Histidine kinase
JS609_RS08790	COG0835	chemotaxis
JS609_RS08795	COG1776	CheC inhibitor of MCP methylation
JS609_RS08800	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
JS609_RS08805	COG1191	sigma factor activity
JS609_RS08815	COG0052	Belongs to the universal ribosomal protein uS2 family
JS609_RS08820	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JS609_RS08825	COG0528	UMP kinase activity
JS609_RS08830	COG0233	cytoplasmic translational termination
JS609_RS08835	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JS609_RS08840	COG4589	Belongs to the CDS family
JS609_RS08845	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JS609_RS08850	COG0750	zinc metalloprotease
JS609_RS08855	COG0442	prolyl-tRNA aminoacylation
JS609_RS08860	COG2176	DNA-directed DNA polymerase activity
JS609_RS08865	COG0779	Required for maturation of 30S ribosomal subunits
JS609_RS08870	COG0195	Participates in both transcription termination and antitermination
JS609_RS08875	COG2740	Nucleic-acid-binding protein implicated in transcription termination
JS609_RS08880	COG1358	cellular component organization or biogenesis
JS609_RS08885	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JS609_RS08890	COG1550	Protein conserved in bacteria
JS609_RS08895	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JS609_RS08900	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JS609_RS08905	COG0196	riboflavin kinase activity
JS609_RS08910	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JS609_RS08915	COG1185	polyribonucleotide nucleotidyltransferase activity
JS609_RS08920	COG0726	polysaccharide deacetylase
JS609_RS08925	COG0612	Peptidase, M16
JS609_RS08930	COG1873	PFAM PRC-barrel domain
JS609_RS08935	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JS609_RS08940	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JS609_RS08945	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JS609_RS08950	COG0527	aspartate kinase activity
JS609_RS08955	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JS609_RS08960	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JS609_RS08965	COG0740	serine-type endopeptidase activity
JS609_RS08975	COG4980	gas vesicle protein
JS609_RS08975	COG1674	ftsk spoiiie
JS609_RS08980	COG2188	Transcriptional regulator
JS609_RS08985	COG2814	Major facilitator Superfamily
JS609_RS08990	COG0612	Peptidase, M16
JS609_RS08995	COG0612	Peptidase, M16
JS609_RS09000	COG0300	oxidoreductase activity
JS609_RS09015	COG1426	Protein conserved in bacteria
JS609_RS09020	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JS609_RS09025	COG1546	Belongs to the CinA family
JS609_RS09025	COG1058	Belongs to the CinA family
JS609_RS09030	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JS609_RS09035	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JS609_RS09040	COG1418	mRNA catabolic process
JS609_RS09045	COG1692	metallophosphoesterase
JS609_RS09050	COG2359	stage V sporulation protein S
JS609_RS09055	COG1063	alcohol dehydrogenase
JS609_RS09060	COG0156	8-amino-7-oxononanoate synthase activity
JS609_RS09065	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JS609_RS09070	COG4550	Control of competence regulator ComK, YlbF/YmcA
JS609_RS09080	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JS609_RS09085	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JS609_RS09100	COG3226	Transcriptional regulator
JS609_RS09105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JS609_RS09115	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JS609_RS09120	COG3321	synthase
JS609_RS09125	COG2070	2-Nitropropane dioxygenase
JS609_RS09125	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JS609_RS09130	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JS609_RS09135	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JS609_RS09140	COG3425	synthase
JS609_RS09145	COG1024	Enoyl-CoA hydratase
JS609_RS09150	COG1024	Enoyl-CoA hydratase
JS609_RS09155	COG3321	synthase
JS609_RS09155	COG1028	Short-chain dehydrogenase reductase Sdr
JS609_RS09155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JS609_RS09155	COG0318	PFAM AMP-dependent synthetase and ligase
JS609_RS09155	COG0300	oxidoreductase activity
JS609_RS09160	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JS609_RS09160	COG3321	synthase
JS609_RS09160	COG4221	oxidoreductase activity
JS609_RS09160	COG0300	oxidoreductase activity
JS609_RS09165	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JS609_RS09165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JS609_RS09165	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JS609_RS09165	COG1028	Short-chain dehydrogenase reductase Sdr
JS609_RS09165	COG3321	synthase
JS609_RS09170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JS609_RS09170	COG1028	Short-chain dehydrogenase reductase Sdr
JS609_RS09170	COG3321	synthase
JS609_RS09170	COG4221	oxidoreductase activity
JS609_RS09175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JS609_RS09175	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JS609_RS09175	COG3321	synthase
JS609_RS09175	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
JS609_RS09180	COG2124	cytochrome p450
JS609_RS09190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JS609_RS09195	COG1404	Belongs to the peptidase S8 family
JS609_RS09205	COG4195	phage-related replication protein
JS609_RS09210	COG1764	response to oxidative stress
JS609_RS09215	COG2076	Multidrug Resistance protein
JS609_RS09220	COG2076	Multidrug Resistance protein
JS609_RS09235	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JS609_RS09240	COG1923	regulation of RNA biosynthetic process
JS609_RS09255	COG1780	Probably involved in ribonucleotide reductase function
JS609_RS09260	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JS609_RS09265	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JS609_RS09270	COG4112	unkown
JS609_RS09275	COG0860	N-Acetylmuramoyl-L-alanine amidase
JS609_RS09280	COG0464	growth
JS609_RS09285	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JS609_RS09290	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
JS609_RS09295	COG0789	Transcriptional regulator
JS609_RS09300	COG0174	glutamine synthetase
JS609_RS09340	COG0463	Glycosyl transferase, family 2
JS609_RS09355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JS609_RS09380	COG0135	phosphoribosylanthranilate isomerase activity
JS609_RS09385	COG2211	Major facilitator Superfamily
JS609_RS09390	COG3507	Belongs to the glycosyl hydrolase 43 family
JS609_RS09395	COG1940	carbohydrate kinase activity
JS609_RS09400	COG2115	Belongs to the xylose isomerase family
JS609_RS09405	COG1070	Carbohydrate kinase
JS609_RS09415	COG1525	nuclease
JS609_RS09420	COG2814	Major facilitator Superfamily
JS609_RS09425	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JS609_RS09435	COG0756	dUTP diphosphatase activity
JS609_RS09450	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JS609_RS09480	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JS609_RS09495	COG3832	glyoxalase III activity
JS609_RS09505	COG0697	spore germination
JS609_RS09510	COG0531	amino acid
JS609_RS09540	COG4195	phage-related replication protein
JS609_RS09550	COG0346	lactoylglutathione lyase activity
JS609_RS09560	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JS609_RS09565	COG1388	LysM domain
JS609_RS09570	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JS609_RS09575	COG4224	UPF0291 protein
JS609_RS09580	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JS609_RS09590	COG3763	UPF0154 protein
JS609_RS09600	COG0785	Cytochrome C biogenesis protein
JS609_RS09605	COG2201	protein-glutamate methylesterase activity
JS609_RS09610	COG4846	Membrane protein involved in cytochrome C biogenesis
JS609_RS09620	COG0071	Belongs to the small heat shock protein (HSP20) family
JS609_RS09635	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JS609_RS09640	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JS609_RS09660	COG0824	Thioesterase
JS609_RS09670	COG4841	protein insertion into membrane
JS609_RS09675	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JS609_RS09680	COG1832	CoA-binding protein
JS609_RS09685	COG0187	DNA topoisomerase II activity
JS609_RS09690	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JS609_RS09700	COG1115	amino acid carrier protein
JS609_RS09705	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JS609_RS09715	COG5520	Belongs to the glycosyl hydrolase 30 family
JS609_RS09720	COG3507	Belongs to the glycosyl hydrolase 43 family
JS609_RS09725	COG2246	polysaccharide biosynthetic process
JS609_RS09730	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JS609_RS09735	COG0586	Pfam SNARE associated Golgi protein
JS609_RS09740	COG2404	hydrolase activity, acting on ester bonds
JS609_RS09745	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JS609_RS09750	COG1024	Enoyl-CoA hydratase
JS609_RS09755	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JS609_RS09760	COG0511	ligase activity, forming carbon-carbon bonds
JS609_RS09765	COG0439	Biotin carboxylase
JS609_RS09770	COG0318	PFAM AMP-dependent synthetase and ligase
JS609_RS09775	COG1960	acyl-CoA dehydrogenase activity
JS609_RS09790	COG1649	PFAM Uncharacterised BCR, COG1649
JS609_RS09800	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
JS609_RS09800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JS609_RS09805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JS609_RS09810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JS609_RS09815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JS609_RS09820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JS609_RS09825	COG2027	D-alanyl-D-alanine carboxypeptidase
JS609_RS09830	COG2017	converts alpha-aldose to the beta-anomer
JS609_RS09835	COG0534	Mate efflux family protein
JS609_RS09850	COG0582	viral genome integration into host DNA
JS609_RS09855	COG0166	Belongs to the GPI family
JS609_RS09860	COG0405	Gamma-glutamyltransferase
JS609_RS09865	COG0583	DNA-binding transcription factor activity
JS609_RS09870	COG0604	alcohol dehydrogenase
JS609_RS09875	COG0493	'glutamate synthase
JS609_RS09880	COG0067	glutamate synthase
JS609_RS09880	COG0069	glutamate synthase activity
JS609_RS09880	COG0070	glutamate synthase
JS609_RS09885	COG0583	DNA-binding transcription factor activity
JS609_RS09890	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JS609_RS09895	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JS609_RS09905	COG0300	oxidoreductase activity
JS609_RS09910	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
JS609_RS09920	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JS609_RS09940	COG2814	Major facilitator Superfamily
JS609_RS09945	COG1070	Carbohydrate kinase
JS609_RS09950	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JS609_RS09955	COG0243	molybdopterin cofactor binding
JS609_RS09980	COG5278	phosphoserine phosphatase activity
JS609_RS09980	COG0840	transmembrane signaling receptor activity
JS609_RS09985	COG2368	4-hydroxyphenylacetate
JS609_RS09990	COG4305	rare lipoprotein A
JS609_RS09995	COG3619	membrane
JS609_RS10000	COG3866	Pectate lyase
JS609_RS10005	COG2135	peptidase activity
JS609_RS10015	COG2140	Oxalate decarboxylase
JS609_RS10030	COG0456	acetyltransferase
JS609_RS10050	COG2720	vancomycin resistance protein
JS609_RS10060	COG3655	Transcriptional regulator
JS609_RS10065	COG3739	integral membrane protein
JS609_RS10070	COG0583	DNA-binding transcription factor activity
JS609_RS10075	COG0697	spore germination
JS609_RS10085	COG0693	protein deglycase activity
JS609_RS10090	COG2367	Beta-lactamase
JS609_RS10110	COG0574	Belongs to the PEP-utilizing enzyme family
JS609_RS10110	COG3848	Pyruvate phosphate dikinase
JS609_RS10115	COG0726	polysaccharide deacetylase
JS609_RS10125	COG2314	TM2 domain
JS609_RS10130	COG1396	sequence-specific DNA binding
JS609_RS10200	COG1388	LysM domain
JS609_RS10225	COG0457	Tetratricopeptide repeat
JS609_RS10265	COG4282	regulation of fungal-type cell wall biogenesis
JS609_RS10270	COG1231	oxidoreductase activity
JS609_RS10275	COG5434	Belongs to the glycosyl hydrolase 28 family
JS609_RS10280	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JS609_RS10285	COG0662	Cupin 2, conserved barrel domain protein
JS609_RS10285	COG2207	Transcriptional regulator
JS609_RS10290	COG0456	acetyltransferase
JS609_RS10295	COG1309	transcriptional regulator
JS609_RS10300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JS609_RS10305	COG3708	Transcriptional regulator
JS609_RS10310	COG2378	regulation of single-species biofilm formation
JS609_RS10320	COG0640	Transcriptional regulator
JS609_RS10325	COG0741	lytic transglycosylase activity
JS609_RS10330	COG2322	membrane
JS609_RS10350	COG3239	Fatty acid desaturase
JS609_RS10355	COG4585	Histidine kinase
JS609_RS10360	COG2197	response regulator
JS609_RS10365	COG3584	3D domain protein
JS609_RS10365	COG1388	LysM domain
JS609_RS10370	COG0514	ATP-dependent DNA helicase (RecQ)
JS609_RS10380	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JS609_RS10385	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JS609_RS10400	COG0071	Belongs to the small heat shock protein (HSP20) family
JS609_RS10425	COG1012	belongs to the aldehyde dehydrogenase family
JS609_RS10430	COG1657	PFAM Prenyltransferase squalene oxidase
JS609_RS10435	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JS609_RS10440	COG0733	neurotransmitter:sodium symporter activity
JS609_RS10445	COG0385	Bile acid
JS609_RS10450	COG0508	dehydrogenase complex catalyzes the overall conversion of
JS609_RS10455	COG0567	Dehydrogenase, E1 component
JS609_RS10460	COG4548	von Willebrand factor, type A
JS609_RS10465	COG0714	Associated with various cellular activities
JS609_RS10470	COG2032	superoxide dismutase activity
JS609_RS10475	COG1388	LysM domain
JS609_RS10475	COG0791	NLP P60 protein
JS609_RS10480	COG1819	glycosyl
JS609_RS10485	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JS609_RS10490	COG0534	Mate efflux family protein
JS609_RS10495	COG1366	Belongs to the anti-sigma-factor antagonist family
JS609_RS10500	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JS609_RS10505	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JS609_RS10515	COG2962	Rard protein
JS609_RS10535	COG1942	4-Oxalocrotonate Tautomerase
JS609_RS10540	COG1733	regulation of RNA biosynthetic process
JS609_RS10545	COG0778	Nitroreductase
JS609_RS10550	COG0400	carboxylic ester hydrolase activity
JS609_RS10555	COG0346	lactoylglutathione lyase activity
JS609_RS10565	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JS609_RS10570	COG3409	Peptidoglycan-binding domain 1 protein
JS609_RS10570	COG0793	Belongs to the peptidase S41A family
JS609_RS10575	COG2226	methyltransferase
JS609_RS10585	COG1876	peptidase activity
JS609_RS10590	COG0813	purine-nucleoside phosphorylase activity
JS609_RS10605	COG0671	phosphoesterase, PA-phosphatase related
JS609_RS10625	COG4479	Belongs to the UPF0346 family
JS609_RS10635	COG1509	lysine 2,3-aminomutase activity
JS609_RS10640	COG0456	acetyltransferase
JS609_RS10645	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JS609_RS10650	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JS609_RS10655	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JS609_RS10660	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JS609_RS10675	COG0456	acetyltransferase
JS609_RS10680	COG0463	Glycosyl transferase, family 2
JS609_RS10695	COG4641	Protein conserved in bacteria
JS609_RS10700	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
JS609_RS10705	COG1086	Polysaccharide biosynthesis protein
JS609_RS10710	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JS609_RS10715	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JS609_RS10720	COG1846	Transcriptional regulator
JS609_RS10725	COG0534	Mate efflux family protein
JS609_RS10735	COG4698	Protein conserved in bacteria
JS609_RS10740	COG2755	lipolytic protein G-D-S-L family
JS609_RS10745	COG1999	signal sequence binding
JS609_RS10755	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JS609_RS10760	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JS609_RS10765	COG1272	protein, Hemolysin III
JS609_RS10770	COG0204	Acyl-transferase
JS609_RS10775	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JS609_RS10780	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JS609_RS10785	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JS609_RS10795	COG2521	methyltransferase
JS609_RS10795	COG2136	Putative SAM-dependent methyltransferase
JS609_RS10805	COG0129	dihydroxy-acid dehydratase activity
JS609_RS10810	COG1413	lyase activity
JS609_RS10815	COG1418	mRNA catabolic process
JS609_RS10820	COG0386	Belongs to the glutathione peroxidase family
JS609_RS10825	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
JS609_RS10830	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JS609_RS10840	COG1278	Cold shock
JS609_RS10860	COG0328	RNA-DNA hybrid ribonuclease activity
JS609_RS10865	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JS609_RS10870	COG0328	RNA-DNA hybrid ribonuclease activity
JS609_RS10880	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JS609_RS10895	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JS609_RS10905	COG1755	Isoprenylcysteine carboxyl methyltransferase
JS609_RS10910	COG3424	synthase
JS609_RS10915	COG2233	PERMEase
JS609_RS10920	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JS609_RS10925	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
JS609_RS10935	COG0800	Aldolase
JS609_RS10940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JS609_RS10945	COG1609	Transcriptional regulator
JS609_RS10950	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
JS609_RS10955	COG1028	Short-chain dehydrogenase reductase Sdr
JS609_RS10960	COG1199	ATP-dependent helicase activity
JS609_RS10975	COG0116	Belongs to the methyltransferase superfamily
JS609_RS10990	COG4474	Belongs to the UPF0398 family
JS609_RS11005	COG3359	exonuclease
JS609_RS11010	COG1205	dead DEAH box helicase
JS609_RS11010	COG1111	helicase
JS609_RS11015	COG2190	(PTS) system
JS609_RS11020	COG0071	Belongs to the small heat shock protein (HSP20) family
JS609_RS11055	COG3331	DNA recombination
JS609_RS11060	COG4499	WXG100 protein secretion system (Wss), protein YukC
JS609_RS11060	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JS609_RS11070	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JS609_RS11075	COG3935	DnaD domain protein
JS609_RS11080	COG0017	Asparaginyl-tRNA synthetase
JS609_RS11085	COG0436	Aminotransferase
JS609_RS11090	COG5353	protein conserved in bacteria
JS609_RS11100	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JS609_RS11100	COG1199	ATP-dependent helicase activity
JS609_RS11105	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JS609_RS11110	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JS609_RS11115	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JS609_RS11120	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
JS609_RS11120	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
JS609_RS11125	COG0617	tRNA 3'-terminal CCA addition
JS609_RS11130	COG0438	transferase activity, transferring glycosyl groups
JS609_RS11135	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JS609_RS11140	COG1803	Methylglyoxal synthase
JS609_RS11145	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JS609_RS11150	COG1694	Mazg nucleotide pyrophosphohydrolase
JS609_RS11155	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JS609_RS11165	COG4347	Protein of unknown function (DUF1405)
JS609_RS11170	COG2010	Cytochrome c
JS609_RS11170	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JS609_RS11175	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JS609_RS11180	COG0723	plastoquinol--plastocyanin reductase activity
JS609_RS11190	COG5582	Belongs to the UPF0302 family
JS609_RS11195	COG0457	Tetratricopeptide repeat
JS609_RS11200	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JS609_RS11205	COG0287	Prephenate dehydrogenase
JS609_RS11215	COG0159	tryptophan synthase activity
JS609_RS11220	COG0133	tryptophan synthase activity
JS609_RS11225	COG0135	phosphoribosylanthranilate isomerase activity
JS609_RS11235	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JS609_RS11240	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JS609_RS11245	COG4401	Chorismate mutase type I
JS609_RS11250	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JS609_RS11255	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JS609_RS11260	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JS609_RS11265	COG0105	UTP biosynthetic process
JS609_RS11270	COG0142	geranyltranstransferase activity
JS609_RS11275	COG2226	methyltransferase
JS609_RS11280	COG0142	geranyltranstransferase activity
JS609_RS11290	COG0302	gtp cyclohydrolase
JS609_RS11295	COG0776	regulation of translation
JS609_RS11300	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JS609_RS11315	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JS609_RS11320	COG1160	GTP binding
JS609_RS11345	COG1304	FMN binding
JS609_RS11350	COG0539	negative regulation of cytoplasmic translation
JS609_RS11355	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JS609_RS11365	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
JS609_RS11370	COG2959	enzyme of heme biosynthesis
JS609_RS11375	COG3773	Cell wall hydrolase
JS609_RS11375	COG3409	Peptidoglycan-binding domain 1 protein
JS609_RS11380	COG2339	peptidase activity
JS609_RS11390	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JS609_RS11395	COG4862	establishment of competence for transformation
JS609_RS11400	COG1408	metallophosphoesterase
JS609_RS11410	COG1388	LysM domain
JS609_RS11415	COG1266	CAAX protease self-immunity
JS609_RS11420	COG0514	ATP-dependent DNA helicase (RecQ)
JS609_RS11425	COG4955	Helix-turn-helix domain
JS609_RS11430	COG1141	Ferredoxin
JS609_RS11435	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JS609_RS11440	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JS609_RS11445	COG0710	3-dehydroquinate dehydratase activity
JS609_RS11455	COG1595	DNA-templated transcription, initiation
JS609_RS11460	COG5002	protein histidine kinase activity
JS609_RS11465	COG0745	RESPONSE REGULATOR receiver
JS609_RS11470	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JS609_RS11475	COG1333	cytochrome c biogenesis protein
JS609_RS11480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JS609_RS11485	COG1187	pseudouridine synthase activity
JS609_RS11490	COG0700	Nucleoside recognition
JS609_RS11495	COG2715	membrane protein required for spore maturation
JS609_RS11500	COG1686	Belongs to the peptidase S11 family
JS609_RS11510	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JS609_RS11515	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JS609_RS11520	COG1547	Domain of unknown function (DUF309)
JS609_RS11525	COG0456	acetyltransferase
JS609_RS11530	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JS609_RS11535	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JS609_RS11535	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JS609_RS11540	COG0307	riboflavin synthase, alpha
JS609_RS11545	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JS609_RS11545	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JS609_RS11555	COG0681	Belongs to the peptidase S26 family
JS609_RS11565	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
JS609_RS11580	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JS609_RS11585	COG4086	secreted protein
JS609_RS11590	COG0019	diaminopimelate decarboxylase activity
JS609_RS11595	COG0697	spore germination
JS609_RS11630	COG1191	sigma factor activity
JS609_RS11635	COG2172	sigma factor antagonist activity
JS609_RS11640	COG1366	Belongs to the anti-sigma-factor antagonist family
JS609_RS11645	COG1686	Belongs to the peptidase S11 family
JS609_RS11650	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JS609_RS11655	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JS609_RS11660	COG4974	Belongs to the 'phage' integrase family
JS609_RS11670	COG0735	belongs to the Fur family
JS609_RS11675	COG1300	Membrane
JS609_RS11685	COG0281	malic enzyme
JS609_RS11690	COG1757	Na H antiporter
JS609_RS11695	COG1027	Aspartate ammonia-lyase
JS609_RS11700	COG0252	asparaginase activity
JS609_RS11705	COG1396	sequence-specific DNA binding
JS609_RS11710	COG1379	DNA repair
JS609_RS11715	COG0494	nUDIX hydrolase
JS609_RS11725	COG0667	Aldo Keto reductase
JS609_RS11735	COG1073	alpha beta
JS609_RS11745	COG4918	Iron-sulphur cluster biosynthesis
JS609_RS11750	COG0456	acetyltransferase
JS609_RS11750	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JS609_RS11755	COG2329	Antibiotic biosynthesis monooxygenase
JS609_RS11760	COG0456	acetyltransferase
JS609_RS11770	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JS609_RS11780	COG2211	Major facilitator Superfamily
JS609_RS11790	COG0346	lactoylglutathione lyase activity
JS609_RS11795	COG1072	(Pantothenic acid kinase))
JS609_RS11800	COG3048	D-serine ammonia-lyase activity
JS609_RS11805	COG0300	oxidoreductase activity
JS609_RS11810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JS609_RS11815	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JS609_RS11820	COG4187	Peptidase family M20/M25/M40
JS609_RS11825	COG1902	pentaerythritol trinitrate reductase activity
JS609_RS11830	COG0596	Alpha beta hydrolase
JS609_RS11840	COG1234	tRNA 3'-trailer cleavage
JS609_RS11845	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JS609_RS11850	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JS609_RS11855	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JS609_RS11865	COG0706	membrane insertase activity
JS609_RS11870	COG3361	conserved protein (COG2071)
JS609_RS11875	COG2195	Cleaves the N-terminal amino acid of tripeptides
JS609_RS11880	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JS609_RS11885	COG0346	lactoylglutathione lyase activity
JS609_RS11895	COG1376	ErfK ybiS ycfS ynhG family protein
JS609_RS11900	COG4129	membrane
JS609_RS11905	COG1126	abc transporter atp-binding protein
JS609_RS11910	COG0765	amino acid transport
JS609_RS11915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JS609_RS11925	COG1597	lipid kinase activity
JS609_RS11930	COG2814	Major facilitator Superfamily
JS609_RS11935	COG4978	Transcriptional regulator
JS609_RS11935	COG0789	Transcriptional regulator
JS609_RS11940	COG0508	dehydrogenase complex catalyzes the overall conversion of
JS609_RS11945	COG0022	dehydrogenase e1 component
JS609_RS11950	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JS609_RS11955	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JS609_RS11960	COG3426	butyrate kinase activity
JS609_RS11965	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JS609_RS11970	COG0280	phosphate acetyltransferase
JS609_RS11975	COG3829	transcription factor binding
JS609_RS11975	COG3290	protein histidine kinase activity
JS609_RS11985	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JS609_RS11990	COG2079	MmgE PrpD family protein
JS609_RS11995	COG0372	Belongs to the citrate synthase family
JS609_RS12000	COG1960	acyl-CoA dehydrogenase activity
JS609_RS12005	COG1250	3-hydroxyacyl-CoA dehydrogenase
JS609_RS12010	COG0183	Belongs to the thiolase family
JS609_RS12015	COG0584	glycerophosphoryl diester phosphodiesterase
JS609_RS12020	COG0860	N-Acetylmuramoyl-L-alanine amidase
JS609_RS12035	COG1902	pentaerythritol trinitrate reductase activity
JS609_RS12040	COG0745	RESPONSE REGULATOR receiver
JS609_RS12045	COG0750	zinc metalloprotease
JS609_RS12050	COG0497	DNA recombination
JS609_RS12055	COG1438	arginine binding
JS609_RS12060	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
JS609_RS12065	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JS609_RS12070	COG0142	geranyltranstransferase activity
JS609_RS12075	COG1722	exodeoxyribonuclease VII activity
JS609_RS12080	COG1570	exodeoxyribonuclease VII activity
JS609_RS12085	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JS609_RS12090	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JS609_RS12095	COG1302	Protein conserved in bacteria
JS609_RS12100	COG0439	Biotin carboxylase
JS609_RS12105	COG0511	ligase activity, forming carbon-carbon bonds
JS609_RS12145	COG3854	ATPases associated with a variety of cellular activities
JS609_RS12155	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JS609_RS12160	COG0006	proline dipeptidase activity
JS609_RS12165	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JS609_RS12175	COG3872	metal-dependent enzyme
JS609_RS12185	COG1752	Esterase of the alpha-beta hydrolase superfamily
JS609_RS12190	COG1321	iron dependent repressor
JS609_RS12195	COG0095	Lipoate-protein ligase
JS609_RS12200	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JS609_RS12205	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JS609_RS12210	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JS609_RS12215	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JS609_RS12220	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JS609_RS12235	COG1396	sequence-specific DNA binding
JS609_RS12245	COG0681	Belongs to the peptidase S26 family
JS609_RS12270	COG4940	Competence protein ComGF
JS609_RS12280	COG4970	Tfp pilus assembly protein FimT
JS609_RS12285	COG4537	Required for transformation and DNA binding
JS609_RS12290	COG1459	type II secretion system
JS609_RS12295	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JS609_RS12300	COG0517	IMP dehydrogenase activity
JS609_RS12305	COG0598	Magnesium transport protein CorA
JS609_RS12310	COG1253	flavin adenine dinucleotide binding
JS609_RS12315	COG1366	Belongs to the anti-sigma-factor antagonist family
JS609_RS12325	COG1393	Belongs to the ArsC family
JS609_RS12335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JS609_RS12345	COG0011	TIGRFAM Protein of
JS609_RS12355	COG2866	Carboxypeptidase
JS609_RS12360	COG1368	sulfuric ester hydrolase activity
JS609_RS12365	COG1940	carbohydrate kinase activity
JS609_RS12370	COG4483	Protein conserved in bacteria
JS609_RS12375	COG0457	Tetratricopeptide repeat
JS609_RS12375	COG0705	Rhomboid family
JS609_RS12385	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JS609_RS12395	COG0438	transferase activity, transferring glycosyl groups
JS609_RS12410	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JS609_RS12415	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JS609_RS12420	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JS609_RS12425	COG0581	inorganic phosphate transmembrane transporter activity
JS609_RS12430	COG0573	inorganic phosphate transmembrane transporter activity
JS609_RS12435	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JS609_RS12440	COG0768	penicillin binding
JS609_RS12445	COG0477	Major facilitator Superfamily
JS609_RS12450	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JS609_RS12455	COG2839	Protein conserved in bacteria
JS609_RS12460	COG5521	maltodextrose utilization protein MalA
JS609_RS12465	COG1388	LysM domain
JS609_RS12470	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JS609_RS12475	COG4709	membrane
JS609_RS12480	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
JS609_RS12485	COG0735	belongs to the Fur family
JS609_RS12490	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JS609_RS12500	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JS609_RS12505	COG0513	Belongs to the DEAD box helicase family
JS609_RS12515	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JS609_RS12520	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JS609_RS12525	COG2384	SAM-dependent methyltransferase
JS609_RS12530	COG2010	Cytochrome c
JS609_RS12535	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JS609_RS12540	COG0358	DNA primase activity
JS609_RS12545	COG1671	Belongs to the UPF0178 family
JS609_RS12550	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JS609_RS12555	COG0517	IMP dehydrogenase activity
JS609_RS12560	COG0751	glycine-tRNA ligase activity
JS609_RS12565	COG0752	glycyl-tRNA synthetase alpha subunit
JS609_RS12570	COG1381	Involved in DNA repair and RecF pathway recombination
JS609_RS12580	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JS609_RS12585	COG0295	cytidine deaminase activity
JS609_RS12590	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JS609_RS12595	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JS609_RS12600	COG1480	7TM receptor with intracellular HD hydrolase
JS609_RS12605	COG1702	phosphate starvation-inducible protein PhoH
JS609_RS12610	COG0561	phosphatase activity
JS609_RS12625	COG4864	UPF0365 protein
JS609_RS12630	COG1030	water channel activity
JS609_RS12635	COG1610	YqeY-like protein
JS609_RS12645	COG1283	sodium-dependent phosphate transmembrane transporter activity
JS609_RS12650	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JS609_RS12655	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JS609_RS12660	COG2264	protein methyltransferase activity
JS609_RS12665	COG0484	heat shock protein binding
JS609_RS12670	COG0443	Heat shock 70 kDa protein
JS609_RS12675	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JS609_RS12680	COG1420	regulation of RNA biosynthetic process
JS609_RS12685	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JS609_RS12690	COG0481	GTPase activity
JS609_RS12700	COG0860	N-Acetylmuramoyl-L-alanine amidase
JS609_RS12705	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
JS609_RS12710	COG0268	Binds directly to 16S ribosomal RNA
JS609_RS12715	COG1466	dna polymerase III delta subunit
JS609_RS12730	COG2333	competence protein COMEC
JS609_RS12730	COG0658	competence protein
JS609_RS12735	COG2131	deaminase
JS609_RS12740	COG1596	polysaccharide export
JS609_RS12740	COG1555	photosystem II stabilization
JS609_RS12745	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JS609_RS12750	COG2226	methyltransferase
JS609_RS12755	COG0799	negative regulation of ribosome biogenesis
JS609_RS12760	COG1713	HD superfamily hydrolase involved in NAD metabolism
JS609_RS12765	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JS609_RS12770	COG1534	Rna-binding protein
JS609_RS12775	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JS609_RS12780	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JS609_RS12785	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
JS609_RS12795	COG2755	lipolytic protein G-D-S-L family
JS609_RS12800	COG3409	Peptidoglycan-binding domain 1 protein
JS609_RS12800	COG5632	N-Acetylmuramoyl-L-alanine amidase
JS609_RS12805	COG0398	Pfam SNARE associated Golgi protein
JS609_RS12820	COG3209	COG3209 Rhs family protein
JS609_RS12835	COG0477	Major facilitator Superfamily
JS609_RS12840	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JS609_RS12855	COG0604	alcohol dehydrogenase
JS609_RS12875	COG0300	oxidoreductase activity
JS609_RS12880	COG1902	pentaerythritol trinitrate reductase activity
JS609_RS12885	COG0596	Alpha beta hydrolase
JS609_RS12885	COG0508	dehydrogenase complex catalyzes the overall conversion of
JS609_RS12890	COG1309	transcriptional regulator
JS609_RS12900	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JS609_RS12905	COG1331	Highly conserved protein containing a thioredoxin domain
JS609_RS12915	COG0640	Transcriptional regulator
JS609_RS12920	COG0457	Tetratricopeptide repeat
JS609_RS12930	COG5444	nuclease activity
JS609_RS12940	COG5632	N-Acetylmuramoyl-L-alanine amidase
JS609_RS12940	COG3409	Peptidoglycan-binding domain 1 protein
JS609_RS12955	COG5484	DNA packaging
JS609_RS12975	COG3677	Transposase
JS609_RS13020	COG0563	adenylate kinase activity
JS609_RS13025	COG2856	Zn peptidase
JS609_RS13045	COG4124	Belongs to the glycosyl hydrolase 26 family
JS609_RS13050	COG0730	response to heat
JS609_RS13055	COG0425	Belongs to the sulfur carrier protein TusA family
JS609_RS13070	COG0425	Belongs to the sulfur carrier protein TusA family
JS609_RS13070	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JS609_RS13080	COG2210	Belongs to the sulfur carrier protein TusA family
JS609_RS13085	COG1937	Protein conserved in bacteria
JS609_RS13095	COG0662	Cupin 2, conserved barrel domain protein
JS609_RS13110	COG4978	Transcriptional regulator
JS609_RS13110	COG0789	Transcriptional regulator
JS609_RS13115	COG2814	Major facilitator Superfamily
JS609_RS13120	COG0456	acetyltransferase
JS609_RS13125	COG1253	flavin adenine dinucleotide binding
JS609_RS13135	COG0697	spore germination
JS609_RS13140	COG0583	DNA-binding transcription factor activity
JS609_RS13145	COG2072	flavoprotein involved in K transport
JS609_RS13150	COG1230	cation diffusion facilitator family transporter
JS609_RS13155	COG1942	4-Oxalocrotonate Tautomerase
JS609_RS13160	COG0583	DNA-binding transcription factor activity
JS609_RS13170	COG1114	Component of the transport system for branched-chain amino acids
JS609_RS13175	COG1687	branched-chain amino acid
JS609_RS13180	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
JS609_RS13185	COG1522	sequence-specific DNA binding
JS609_RS13190	COG2732	(Barnase) inhibitor
JS609_RS13195	COG2124	cytochrome p450
JS609_RS13205	COG1335	isochorismatase
JS609_RS13220	COG2318	DinB family
JS609_RS13230	COG2070	2-Nitropropane dioxygenase
JS609_RS13235	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JS609_RS13255	COG3443	Belongs to the bacterial solute-binding protein 9 family
JS609_RS13260	COG1595	DNA-templated transcription, initiation
JS609_RS13265	COG0667	Aldo Keto reductase
JS609_RS13270	COG2851	Citrate transporter
JS609_RS13275	COG0583	DNA-binding transcription factor activity
JS609_RS13280	COG2828	Protein conserved in bacteria
JS609_RS13285	COG3409	Peptidoglycan-binding domain 1 protein
JS609_RS13290	COG5566	PFAM Mor transcription activator
JS609_RS13295	COG0596	Alpha beta hydrolase
JS609_RS13300	COG4991	sh3 domain protein
JS609_RS13305	COG4991	sh3 domain protein
JS609_RS13315	COG0346	lactoylglutathione lyase activity
JS609_RS13325	COG5577	PFAM Coat F domain
JS609_RS13330	COG1063	alcohol dehydrogenase
JS609_RS13340	COG5577	PFAM Coat F domain
JS609_RS13345	COG0789	Transcriptional regulator
JS609_RS13355	COG1064	alcohol dehydrogenase
JS609_RS13360	COG0693	protein deglycase activity
JS609_RS13365	COG1621	beta-fructofuranosidase activity
JS609_RS13375	COG3716	PTS system mannose fructose sorbose family IID component
JS609_RS13380	COG3715	PTS system
JS609_RS13385	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JS609_RS13390	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
JS609_RS13395	COG3933	PFAM sigma-54 factor interaction domain-containing protein
JS609_RS13395	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JS609_RS13405	COG1113	amino acid transport
JS609_RS13410	COG1280	lysine exporter protein (LysE YggA)
JS609_RS13415	COG1378	Sugar-specific transcriptional regulator TrmB
JS609_RS13420	COG1595	DNA-templated transcription, initiation
JS609_RS13440	COG2124	cytochrome p450
JS609_RS13440	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JS609_RS13445	COG1309	transcriptional regulator
JS609_RS13450	COG2226	methyltransferase
JS609_RS13465	COG2116	formate transmembrane transporter activity
JS609_RS13470	COG5609	conserved protein (DUF2294)
JS609_RS13475	COG3383	formate dehydrogenase (NAD+) activity
JS609_RS13480	COG2427	Protein of unknown function (DUF1641)
JS609_RS13490	COG0626	cystathionine gamma-synthase activity
JS609_RS13495	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JS609_RS13500	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JS609_RS13505	COG2226	methyltransferase
JS609_RS13520	COG0768	penicillin binding
JS609_RS13525	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JS609_RS13530	COG0572	uridine kinase
JS609_RS13535	COG0826	peptidase U32
JS609_RS13540	COG0826	peptidase U32
JS609_RS13545	COG4122	O-methyltransferase activity
JS609_RS13550	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JS609_RS13555	COG3906	Belongs to the UPF0473 family
JS609_RS13560	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JS609_RS13565	COG4472	Bacterial protein of unknown function (DUF965)
JS609_RS13570	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JS609_RS13575	COG0628	permease
JS609_RS13580	COG1126	abc transporter atp-binding protein
JS609_RS13585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JS609_RS13590	COG0765	amino acid transport
JS609_RS13595	COG0765	amino acid transport
JS609_RS13610	COG3881	PFAM PRC-barrel domain
JS609_RS13615	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JS609_RS13620	COG0457	Tetratricopeptide repeat
JS609_RS13625	COG0482	sulfurtransferase activity
JS609_RS13630	COG1104	cysteine desulfurase activity
JS609_RS13635	COG1959	2 iron, 2 sulfur cluster binding
JS609_RS13640	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JS609_RS13645	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JS609_RS13655	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JS609_RS13660	COG0124	histidyl-tRNA synthetase
JS609_RS13670	COG3103	Sh3 type 3 domain protein
JS609_RS13670	COG4991	sh3 domain protein
JS609_RS13670	COG0860	N-Acetylmuramoyl-L-alanine amidase
JS609_RS13675	COG1490	D-aminoacyl-tRNA deacylase activity
JS609_RS13680	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JS609_RS13685	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JS609_RS13690	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JS609_RS13690	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JS609_RS13695	COG5416	Lipopolysaccharide assembly protein A domain
JS609_RS13700	COG0490	domain, Protein
JS609_RS13705	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JS609_RS13705	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JS609_RS13715	COG2244	polysaccharide biosynthetic process
JS609_RS13720	COG2323	membrane
JS609_RS13730	COG1862	Preprotein translocase
JS609_RS13735	COG0343	queuine tRNA-ribosyltransferase activity
JS609_RS13740	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JS609_RS13750	COG2255	four-way junction helicase activity
JS609_RS13755	COG0632	four-way junction helicase activity
JS609_RS13765	COG2814	Major facilitator Superfamily
JS609_RS13775	COG2112	serine threonine protein kinase
JS609_RS13795	COG1115	amino acid carrier protein
JS609_RS13800	COG0217	transcriptional regulatory protein
JS609_RS13810	COG1388	LysM domain
JS609_RS13815	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JS609_RS13820	COG0157	Belongs to the NadC ModD family
JS609_RS13825	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
JS609_RS13830	COG1104	cysteine desulfurase activity
JS609_RS13835	COG1827	regulation of RNA biosynthetic process
JS609_RS13840	COG0077	Prephenate dehydratase
JS609_RS13845	COG4492	Belongs to the UPF0735 family
JS609_RS13850	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JS609_RS13855	COG3290	protein histidine kinase activity
JS609_RS13865	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JS609_RS13870	COG2868	ribosomal protein
JS609_RS13875	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JS609_RS13880	COG1994	Peptidase M50
JS609_RS13885	COG0739	heme binding
JS609_RS13890	COG2894	cell division
JS609_RS13895	COG0850	regulation of cytokinetic process
JS609_RS13900	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
JS609_RS13910	COG1077	Cell shape determining protein MreB Mrl
JS609_RS13915	COG2003	Belongs to the UPF0758 family
JS609_RS13920	COG0424	maF-like protein
JS609_RS13930	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JS609_RS13935	COG0285	dihydrofolate synthase activity
JS609_RS13940	COG0525	valine-tRNA ligase activity
JS609_RS13950	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JS609_RS13955	COG1388	LysM domain
JS609_RS13960	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JS609_RS13965	COG0113	porphobilinogen synthase activity
JS609_RS13970	COG1587	Uroporphyrinogen-III synthase
JS609_RS13975	COG0181	hydroxymethylbilane synthase activity
JS609_RS13980	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JS609_RS13985	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JS609_RS13995	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JS609_RS14000	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JS609_RS14005	COG1067	ATP-dependent peptidase activity
JS609_RS14005	COG0470	DNA polymerase III
JS609_RS14010	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JS609_RS14015	COG0544	peptidyl-prolyl cis-trans isomerase activity
JS609_RS14020	COG1477	protein flavinylation
JS609_RS14020	COG0457	Tetratricopeptide repeat
JS609_RS14025	COG0066	3-isopropylmalate dehydratase activity
JS609_RS14030	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JS609_RS14035	COG0473	3-isopropylmalate dehydrogenase activity
JS609_RS14040	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JS609_RS14045	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JS609_RS14050	COG0440	acetolactate synthase activity
JS609_RS14055	COG0028	Belongs to the TPP enzyme family
JS609_RS14065	COG0454	-acetyltransferase
JS609_RS14070	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
JS609_RS14080	COG0622	Phosphoesterase
JS609_RS14085	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JS609_RS14090	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JS609_RS14095	COG5401	PFAM Sporulation and spore germination
JS609_RS14100	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JS609_RS14105	COG1846	Transcriptional regulator
JS609_RS14115	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JS609_RS14135	COG3409	Peptidoglycan-binding domain 1 protein
JS609_RS14135	COG5632	N-Acetylmuramoyl-L-alanine amidase
JS609_RS14195	COG1388	LysM domain
JS609_RS14195	COG0791	NLP P60 protein
JS609_RS14200	COG3953	SLT domain
JS609_RS14200	COG5280	Phage tail tape measure protein TP901
JS609_RS14270	COG5484	DNA packaging
JS609_RS14295	COG1595	DNA-templated transcription, initiation
JS609_RS14350	COG1484	DNA-dependent DNA replication
JS609_RS14355	COG3935	DnaD domain protein
JS609_RS14360	COG3723	Recombinational DNA repair protein, rece pathway
JS609_RS14365	COG5377	YqaJ viral recombinase family
JS609_RS14390	COG3645	SOS response
JS609_RS14390	COG3646	Phage regulatory protein
JS609_RS14405	COG3620	sequence-specific DNA binding
JS609_RS14415	COG2856	Zn peptidase
JS609_RS14420	COG2197	response regulator
JS609_RS14425	COG0824	Thioesterase
JS609_RS14430	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JS609_RS14435	COG1053	succinate dehydrogenase
JS609_RS14440	COG2009	succinate dehydrogenase
JS609_RS14445	COG1719	4-vinyl reductase, 4VR
JS609_RS14450	COG0527	aspartate kinase activity
JS609_RS14455	COG0322	excinuclease ABC activity
JS609_RS14460	COG3118	belongs to the thioredoxin family
JS609_RS14465	COG3534	alpha-L-arabinofuranosidase
JS609_RS14470	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JS609_RS14475	COG2086	electron transfer activity
JS609_RS14480	COG1024	Enoyl-CoA hydratase
JS609_RS14485	COG1309	transcriptional regulator
JS609_RS14490	COG0318	PFAM AMP-dependent synthetase and ligase
JS609_RS14495	COG3766	membrane
JS609_RS14500	COG1193	negative regulation of DNA recombination
JS609_RS14505	COG1796	DNA polymerase
JS609_RS14505	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JS609_RS14510	COG1286	toxin biosynthetic process
JS609_RS14515	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JS609_RS14520	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JS609_RS14525	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JS609_RS14525	COG0072	phenylalanine-tRNA ligase activity
JS609_RS14530	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JS609_RS14540	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JS609_RS14550	COG3835	regulator
JS609_RS14555	COG0277	FAD linked oxidase domain protein
JS609_RS14560	COG0247	lactate metabolic process
JS609_RS14565	COG0346	lactoylglutathione lyase activity
JS609_RS14575	COG1966	Carbon starvation protein
JS609_RS14580	COG3534	alpha-L-arabinofuranosidase
JS609_RS14585	COG0395	ABC-type sugar transport system, permease component
JS609_RS14590	COG1175	transmembrane transport
JS609_RS14595	COG1653	transport
JS609_RS14600	COG0371	Dehydrogenase
JS609_RS14605	COG0647	UMP catabolic process
JS609_RS14610	COG0235	Class ii aldolase
JS609_RS14615	COG1069	ribulokinase activity
JS609_RS14620	COG2160	L-arabinose isomerase activity
JS609_RS14625	COG3507	Belongs to the glycosyl hydrolase 43 family
JS609_RS14630	COG1363	Peptidase, m42
JS609_RS14640	COG3326	Membrane
JS609_RS14645	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JS609_RS14650	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JS609_RS14655	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JS609_RS14665	COG1346	cytolysis
JS609_RS14670	COG1380	Effector of murein hydrolase LrgA
JS609_RS14675	COG3279	Response regulator of the LytR AlgR family
JS609_RS14680	COG3275	phosphorelay sensor kinase activity
JS609_RS14685	COG1011	Hydrolase
JS609_RS14690	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JS609_RS14700	COG0398	Pfam SNARE associated Golgi protein
JS609_RS14705	COG1484	DNA-dependent DNA replication
JS609_RS14710	COG3611	Membrane attachment protein
JS609_RS14715	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JS609_RS14720	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
JS609_RS14725	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JS609_RS14730	COG1733	regulation of RNA biosynthetic process
JS609_RS14735	COG2814	Major facilitator Superfamily
JS609_RS14740	COG0656	L-ascorbic acid biosynthetic process
JS609_RS14745	COG0237	dephospho-CoA kinase activity
JS609_RS14755	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JS609_RS14760	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JS609_RS14760	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JS609_RS14765	COG5002	protein histidine kinase activity
JS609_RS14770	COG0745	RESPONSE REGULATOR receiver
JS609_RS14775	COG0039	L-malate dehydrogenase activity
JS609_RS14780	COG0538	isocitrate dehydrogenase activity
JS609_RS14785	COG0372	Belongs to the citrate synthase family
JS609_RS14790	COG2707	UPF0756 membrane protein
JS609_RS14795	COG0628	permease
JS609_RS14800	COG3030	protein affecting phage T7 exclusion by the F plasmid
JS609_RS14805	COG0469	pyruvate kinase activity
JS609_RS14810	COG0205	6-phosphofructokinase activity
JS609_RS14815	COG0825	malonyl-CoA metabolic process
JS609_RS14820	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JS609_RS14825	COG0281	malic enzyme
JS609_RS14830	COG0587	DNA-directed DNA polymerase activity
JS609_RS14850	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JS609_RS14860	COG4109	DRTGG domain
JS609_RS14865	COG0730	response to heat
JS609_RS14870	COG1473	amidohydrolase
JS609_RS14875	COG0196	riboflavin kinase activity
JS609_RS14880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JS609_RS14885	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JS609_RS14890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JS609_RS14895	COG1126	abc transporter atp-binding protein
JS609_RS14900	COG0765	amino acid transport
JS609_RS14905	COG0765	amino acid transport
JS609_RS14910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JS609_RS14915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JS609_RS14920	COG0454	-acetyltransferase
JS609_RS14925	COG0583	DNA-binding transcription factor activity
JS609_RS14930	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JS609_RS14935	COG1028	Short-chain dehydrogenase reductase Sdr
JS609_RS14940	COG0165	Argininosuccinate lyase
JS609_RS14945	COG0137	argininosuccinate synthase activity
JS609_RS14950	COG0521	Mo-molybdopterin cofactor biosynthetic process
JS609_RS14955	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JS609_RS14965	COG0827	DNA restriction-modification system
JS609_RS14970	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JS609_RS14975	COG3874	Sporulation protein YtfJ
JS609_RS14985	COG1714	RDD family
JS609_RS14990	COG0616	signal peptide processing
JS609_RS14995	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JS609_RS15000	COG1574	metal-dependent hydrolase with the TIM-barrel fold
JS609_RS15005	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JS609_RS15015	COG0301	tRNA thio-modification
JS609_RS15020	COG1104	cysteine desulfurase activity
JS609_RS15025	COG1114	Component of the transport system for branched-chain amino acids
JS609_RS15030	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JS609_RS15035	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JS609_RS15040	COG1309	transcriptional regulator
JS609_RS15045	COG1956	GAF domain-containing protein
JS609_RS15050	COG2203	Gaf domain
JS609_RS15050	COG2199	diguanylate cyclase activity
JS609_RS15055	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JS609_RS15060	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JS609_RS15065	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JS609_RS15070	COG0454	-acetyltransferase
JS609_RS15075	COG0517	IMP dehydrogenase activity
JS609_RS15080	COG0123	including yeast histone deacetylase and acetoin utilization protein
JS609_RS15085	COG1360	Flagellar Motor Protein
JS609_RS15090	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JS609_RS15095	COG1609	Transcriptional regulator
JS609_RS15100	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JS609_RS15100	COG1605	Chorismate mutase
JS609_RS15105	COG3118	belongs to the thioredoxin family
JS609_RS15110	COG4980	gas vesicle protein
JS609_RS15115	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
JS609_RS15120	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JS609_RS15125	COG1674	ftsk spoiiie
JS609_RS15130	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JS609_RS15135	COG4848	Belongs to the UPF0354 family
JS609_RS15140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JS609_RS15155	COG1363	Peptidase, m42
JS609_RS15160	COG5584	Small secreted protein
JS609_RS15165	COG0281	malic enzyme
JS609_RS15170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JS609_RS15175	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JS609_RS15185	COG0510	thiamine kinase activity
JS609_RS15190	COG1523	belongs to the glycosyl hydrolase 13 family
JS609_RS15195	COG1597	lipid kinase activity
JS609_RS15205	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JS609_RS15210	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JS609_RS15215	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JS609_RS15220	COG2252	PERMEase
JS609_RS15225	COG4473	ABC transporter
JS609_RS15230	COG1131	(ABC) transporter
JS609_RS15235	COG1349	DNA-binding transcription factor activity
JS609_RS15240	COG1187	pseudouridine synthase activity
JS609_RS15245	COG2244	polysaccharide biosynthetic process
JS609_RS15250	COG2081	HI0933 family
JS609_RS15255	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JS609_RS15265	COG5578	integral membrane protein
JS609_RS15270	COG0673	inositol 2-dehydrogenase activity
JS609_RS15275	COG1653	transport
JS609_RS15285	COG4209	transmembrane transport
JS609_RS15290	COG2207	Transcriptional regulator
JS609_RS15295	COG1653	transport
JS609_RS15300	COG0395	ABC-type sugar transport system, permease component
JS609_RS15305	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JS609_RS15310	COG2124	cytochrome p450
JS609_RS15315	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JS609_RS15325	COG0156	8-amino-7-oxononanoate synthase activity
JS609_RS15330	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JS609_RS15340	COG1073	alpha beta
JS609_RS15345	COG1609	Transcriptional regulator
JS609_RS15350	COG1653	transport
JS609_RS15355	COG1175	transmembrane transport
JS609_RS15360	COG0395	ABC-type sugar transport system, permease component
JS609_RS15365	COG1486	melibiose metabolic process
JS609_RS15370	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JS609_RS15375	COG0495	leucyl-tRNA aminoacylation
JS609_RS15385	COG1366	Belongs to the anti-sigma-factor antagonist family
JS609_RS15385	COG2202	Pas domain
JS609_RS15390	COG2814	Major facilitator Superfamily
JS609_RS15395	COG2433	Pfam Transposase IS66
JS609_RS15400	COG0577	efflux transmembrane transporter activity
JS609_RS15405	COG1136	(ABC) transporter
JS609_RS15410	COG2205	protein histidine kinase activity
JS609_RS15415	COG0745	RESPONSE REGULATOR receiver
JS609_RS15420	COG0577	efflux transmembrane transporter activity
JS609_RS15425	COG1136	(ABC) transporter
JS609_RS15440	COG1131	(ABC) transporter
JS609_RS15445	COG1725	Transcriptional regulator
JS609_RS15460	COG1242	4 iron, 4 sulfur cluster binding
JS609_RS15465	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
JS609_RS15475	COG2267	carboxylic ester hydrolase activity
JS609_RS15480	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JS609_RS15485	COG1113	amino acid transport
JS609_RS15490	COG0367	asparagine synthase
JS609_RS15495	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JS609_RS15500	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JS609_RS15510	COG1506	peptidase
JS609_RS15515	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JS609_RS15520	COG1116	anion transmembrane transporter activity
JS609_RS15525	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JS609_RS15530	COG0494	nUDIX hydrolase
JS609_RS15535	COG4824	toxin secretion phage lysis holin
JS609_RS15540	COG0783	Belongs to the Dps family
JS609_RS15555	COG1854	S-ribosylhomocysteine lyase activity
JS609_RS15560	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JS609_RS15565	COG0288	reversible hydration of carbon dioxide
JS609_RS15570	COG0254	rRNA binding
JS609_RS15575	COG1271	oxidase subunit
JS609_RS15580	COG1294	oxidase, subunit
JS609_RS15590	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JS609_RS15595	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JS609_RS15595	COG1321	iron dependent repressor
JS609_RS15600	COG1121	(ABC) transporter
JS609_RS15605	COG0803	Belongs to the bacterial solute-binding protein 9 family
JS609_RS15610	COG4948	Mandelate Racemase Muconate Lactonizing
JS609_RS15615	COG0318	PFAM AMP-dependent synthetase and ligase
JS609_RS15620	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JS609_RS15625	COG0596	Alpha beta hydrolase
JS609_RS15630	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JS609_RS15635	COG1169	isochorismate synthase
JS609_RS15640	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JS609_RS15645	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JS609_RS15650	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JS609_RS15655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JS609_RS15660	COG0438	transferase activity, transferring glycosyl groups
JS609_RS15670	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JS609_RS15675	COG0438	transferase activity, transferring glycosyl groups
JS609_RS15680	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JS609_RS15685	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
JS609_RS15690	COG0058	SHG alpha-glucan phosphorylase activity
JS609_RS15695	COG0297	glycogen (starch) synthase activity
JS609_RS15700	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JS609_RS15705	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JS609_RS15710	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JS609_RS15835	COG3859	Proton-coupled thiamine transporter YuaJ
JS609_RS15840	COG1247	-acetyltransferase
JS609_RS15845	COG2268	Band 7 protein
JS609_RS15850	COG1585	Membrane protein implicated in regulation of membrane protease activity
JS609_RS15855	COG2318	DinB family
JS609_RS15865	COG1454	alcohol dehydrogenase
JS609_RS15870	COG1012	belongs to the aldehyde dehydrogenase family
JS609_RS15875	COG1510	regulation of RNA biosynthetic process
JS609_RS15885	COG0569	domain protein
JS609_RS15890	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JS609_RS15895	COG4682	membrane
JS609_RS15900	COG1705	Flagellar rod assembly protein muramidase FlgJ
JS609_RS15905	COG0477	Major facilitator Superfamily
JS609_RS15910	COG5553	Cysteine dioxygenase type I
JS609_RS15920	COG1968	undecaprenyl-diphosphatase activity
JS609_RS15925	COG0628	permease
JS609_RS15930	COG0673	inositol 2-dehydrogenase activity
JS609_RS15935	COG4806	L-rhamnose isomerase
JS609_RS15940	COG3254	rhamnose metabolic process
JS609_RS15945	COG1070	Carbohydrate kinase
JS609_RS15950	COG1349	DNA-binding transcription factor activity
JS609_RS15955	COG3347	Dehydrogenase
JS609_RS15955	COG1028	Short-chain dehydrogenase reductase Sdr
JS609_RS15960	COG0840	transmembrane signaling receptor activity
JS609_RS15965	COG0840	transmembrane signaling receptor activity
JS609_RS15970	COG0840	transmembrane signaling receptor activity
JS609_RS15975	COG0840	transmembrane signaling receptor activity
JS609_RS15990	COG0432	Pfam Uncharacterised protein family UPF0047
JS609_RS16000	COG0366	Alpha amylase catalytic
JS609_RS16005	COG1253	flavin adenine dinucleotide binding
JS609_RS16010	COG2738	Putative neutral zinc metallopeptidase
JS609_RS16025	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JS609_RS16040	COG0166	Belongs to the GPI family
JS609_RS16045	COG1979	alcohol dehydrogenase
JS609_RS16050	COG1979	alcohol dehydrogenase
JS609_RS16055	COG2155	Conserved Protein
JS609_RS16060	COG1098	S1 RNA binding domain
JS609_RS16065	COG0436	Aminotransferase
JS609_RS16070	COG1522	sequence-specific DNA binding
JS609_RS16075	COG2267	carboxylic ester hydrolase activity
JS609_RS16085	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JS609_RS16090	COG2205	protein histidine kinase activity
JS609_RS16100	COG5018	Exonuclease
JS609_RS16110	COG2814	Major facilitator Superfamily
JS609_RS16115	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JS609_RS16120	COG3011	Protein conserved in bacteria
JS609_RS16130	COG3290	protein histidine kinase activity
JS609_RS16135	COG4565	transcriptional regulatory protein
JS609_RS16140	COG1744	ABC transporter substrate-binding protein PnrA-like
JS609_RS16145	COG3845	ABC transporter
JS609_RS16150	COG4603	Belongs to the binding-protein-dependent transport system permease family
JS609_RS16155	COG1079	Belongs to the binding-protein-dependent transport system permease family
JS609_RS16160	COG3493	citrate carrier protein
JS609_RS16170	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JS609_RS16170	COG2111	Na H antiporter
JS609_RS16175	COG2111	Na H antiporter
JS609_RS16180	COG1006	Multisubunit Na H antiporter MnhC subunit
JS609_RS16185	COG0651	ATP synthesis coupled electron transport
JS609_RS16190	COG1863	multisubunit Na H antiporter MnhE subunit
JS609_RS16195	COG2212	antiporter activity
JS609_RS16200	COG1320	monovalent cation:proton antiporter activity
JS609_RS16205	COG2050	protein possibly involved in aromatic compounds catabolism
JS609_RS16210	COG2197	response regulator
JS609_RS16215	COG4585	Histidine kinase
JS609_RS16225	COG0142	geranyltranstransferase activity
JS609_RS16245	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
JS609_RS16250	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JS609_RS16255	COG1335	isochorismatase
JS609_RS16260	COG5506	Protein of unknown function (DUF1694)
JS609_RS16275	COG0628	permease
JS609_RS16290	COG1418	mRNA catabolic process
JS609_RS16295	COG1028	Short-chain dehydrogenase reductase Sdr
JS609_RS16305	COG1511	domain protein
JS609_RS16310	COG1674	ftsk spoiiie
JS609_RS16310	COG0433	COG0433 Predicted ATPase
JS609_RS16315	COG4499	WXG100 protein secretion system (Wss), protein YukC
JS609_RS16320	COG5417	Belongs to the EsaB family
JS609_RS16325	COG4842	Belongs to the WXG100 family
JS609_RS16330	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JS609_RS16330	COG2508	Transcriptional regulator
JS609_RS16335	COG0686	Belongs to the AlaDH PNT family
JS609_RS16340	COG5634	Uncharacterized conserved protein (DUF2278)
JS609_RS16345	COG3251	PFAM MbtH domain protein
JS609_RS16350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JS609_RS16355	COG3433	isochorismatase activity
JS609_RS16355	COG1535	isochorismatase
JS609_RS16360	COG1021	2,3-dihydroxybenzoate-AMP ligase
JS609_RS16365	COG1169	isochorismate synthase
JS609_RS16370	COG1028	Short-chain dehydrogenase reductase Sdr
JS609_RS16375	COG2819	hydrolase of the alpha beta superfamily
JS609_RS16380	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JS609_RS16385	COG1268	BioY protein
JS609_RS16390	COG2056	Na+-H+ antiporter family
JS609_RS16395	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JS609_RS16400	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
JS609_RS16405	COG3584	3D domain protein
JS609_RS16420	COG1252	NADH dehydrogenase
JS609_RS16425	COG0492	ferredoxin-NADP+ reductase activity
JS609_RS16435	COG0516	GMP reductase activity
JS609_RS16445	COG2808	Putative FMN-binding domain
JS609_RS16450	COG0456	acetyltransferase
JS609_RS16455	COG0316	Belongs to the HesB IscA family
JS609_RS16460	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JS609_RS16465	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JS609_RS16470	COG4844	belongs to the
JS609_RS16475	COG1252	NADH dehydrogenase
JS609_RS16480	COG4837	Protein of unknown function (DUF1462)
JS609_RS16485	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
JS609_RS16490	COG0823	Involved in the tonB-independent uptake of proteins
JS609_RS16490	COG1506	peptidase
JS609_RS16490	COG4946	Tricorn protease homolog
JS609_RS16495	COG0083	homoserine kinase activity
JS609_RS16500	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JS609_RS16505	COG0460	homoserine dehydrogenase
JS609_RS16510	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JS609_RS16515	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JS609_RS16520	COG0647	UMP catabolic process
JS609_RS16525	COG2445	Protein of unknown function DUF86
JS609_RS16530	COG4470	Protein conserved in bacteria
JS609_RS16540	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JS609_RS16545	COG0739	heme binding
JS609_RS16555	COG3377	Domain of unknown function (DUF1805)
JS609_RS16560	COG0737	Belongs to the 5'-nucleotidase family
JS609_RS16565	COG0730	response to heat
JS609_RS16570	COG1801	Protein of unknown function DUF72
JS609_RS16580	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JS609_RS16585	COG2508	Transcriptional regulator
JS609_RS16590	COG2233	PERMEase
JS609_RS16595	COG2233	PERMEase
JS609_RS16600	COG3195	allantoin biosynthetic process
JS609_RS16600	COG3648	Uricase
JS609_RS16605	COG2351	hydroxyisourate hydrolase activity
JS609_RS16615	COG2080	2 iron, 2 sulfur cluster binding
JS609_RS16620	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JS609_RS16625	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
JS609_RS16630	COG2068	MobA-Related Protein
JS609_RS16635	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
JS609_RS16640	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JS609_RS16645	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JS609_RS16655	COG2356	endonuclease I
JS609_RS16660	COG3842	ATPase activity
JS609_RS16665	COG2188	Transcriptional regulator
JS609_RS16670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JS609_RS16675	COG0395	ABC-type sugar transport system, permease component
JS609_RS16680	COG1175	transmembrane transport
JS609_RS16690	COG2222	sugar isomerase
JS609_RS16695	COG0322	excinuclease ABC activity
JS609_RS16700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JS609_RS16715	COG0719	Fe-S assembly protein
JS609_RS16720	COG0822	iron-sulfur transferase activity
JS609_RS16725	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JS609_RS16730	COG0719	Fe-S assembly protein
JS609_RS16735	COG0396	ATPase activity
JS609_RS16745	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JS609_RS16750	COG1464	Belongs to the NlpA lipoprotein family
JS609_RS16755	COG2011	ABC-type metal ion transport system permease component
JS609_RS16760	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JS609_RS16770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JS609_RS16775	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JS609_RS16785	COG0509	glycine decarboxylation via glycine cleavage system
JS609_RS16790	COG1393	Belongs to the ArsC family
JS609_RS16795	COG1960	acyl-CoA dehydrogenase activity
JS609_RS16800	COG0183	Belongs to the thiolase family
JS609_RS16805	COG1024	Enoyl-CoA hydratase
JS609_RS16805	COG1250	3-hydroxyacyl-CoA dehydrogenase
JS609_RS16815	COG0506	proline dehydrogenase activity
JS609_RS16825	COG5577	PFAM Coat F domain
JS609_RS16830	COG1846	Transcriptional regulator
JS609_RS16835	COG0477	Major facilitator Superfamily
JS609_RS16840	COG1942	4-Oxalocrotonate Tautomerase
JS609_RS16845	COG1028	Short-chain dehydrogenase reductase Sdr
JS609_RS16850	COG0583	DNA-binding transcription factor activity
JS609_RS16860	COG1120	ATPase activity
JS609_RS16875	COG1028	Short-chain dehydrogenase reductase Sdr
JS609_RS16880	COG0783	Belongs to the Dps family
JS609_RS16885	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JS609_RS16890	COG0745	RESPONSE REGULATOR receiver
JS609_RS16895	COG2770	Histidine kinase
JS609_RS16895	COG2205	protein histidine kinase activity
JS609_RS16905	COG1309	transcriptional regulator
JS609_RS16910	COG0114	fumarate hydratase activity
JS609_RS16920	COG0697	spore germination
JS609_RS16925	COG0814	amino acid
JS609_RS16935	COG2197	response regulator
JS609_RS16940	COG4585	Histidine kinase
JS609_RS16945	COG4758	membrane
JS609_RS16950	COG3595	metallopeptidase activity
JS609_RS16955	COG1842	Phage shock protein A
JS609_RS16960	COG4758	membrane
JS609_RS16965	COG2814	Major facilitator Superfamily
JS609_RS16970	COG2096	Adenosyltransferase
JS609_RS16975	COG1120	ATPase activity
JS609_RS16980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JS609_RS16985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JS609_RS16990	COG1028	Short-chain dehydrogenase reductase Sdr
JS609_RS16995	COG3386	PFAM SMP-30 Gluconolaconase
JS609_RS17000	COG2205	protein histidine kinase activity
JS609_RS17005	COG0745	RESPONSE REGULATOR receiver
JS609_RS17015	COG1191	sigma factor activity
JS609_RS17025	COG2140	Oxalate decarboxylase
JS609_RS17035	COG0577	efflux transmembrane transporter activity
JS609_RS17040	COG1136	(ABC) transporter
JS609_RS17045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JS609_RS17050	COG1120	ATPase activity
JS609_RS17055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JS609_RS17060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JS609_RS17065	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JS609_RS17070	COG0531	amino acid
JS609_RS17080	COG1988	membrane-bound metal-dependent
JS609_RS17085	COG1368	sulfuric ester hydrolase activity
JS609_RS17090	COG1910	domain protein
JS609_RS17095	COG0725	ABC transporter, periplasmic molybdate-binding protein
JS609_RS17100	COG4149	molybdate abc transporter
JS609_RS17105	COG0656	L-ascorbic acid biosynthetic process
JS609_RS17115	COG0025	NhaP-type Na H and K H
JS609_RS17120	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JS609_RS17125	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JS609_RS17130	COG3973	AAA domain
JS609_RS17140	COG2860	membrane
JS609_RS17145	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
JS609_RS17150	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JS609_RS17155	COG2217	Heavy metal translocating P-type atpase
JS609_RS17160	COG2217	Heavy metal translocating P-type atpase
JS609_RS17165	COG2608	mercury ion transmembrane transporter activity
JS609_RS17170	COG1937	Protein conserved in bacteria
JS609_RS17175	COG0673	inositol 2-dehydrogenase activity
JS609_RS17180	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JS609_RS17185	COG1289	transmembrane transporter activity
JS609_RS17195	COG2076	Multidrug Resistance protein
JS609_RS17200	COG1309	transcriptional regulator
JS609_RS17205	COG1028	Short-chain dehydrogenase reductase Sdr
JS609_RS17215	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JS609_RS17220	COG0557	exoribonuclease II activity
JS609_RS17225	COG1647	Serine aminopeptidase, S33
JS609_RS17230	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JS609_RS17235	COG0596	Alpha beta hydrolase
JS609_RS17240	COG1476	TRANSCRIPTIONal
JS609_RS17245	COG1396	sequence-specific DNA binding
JS609_RS17250	COG1396	sequence-specific DNA binding
JS609_RS17255	COG1733	regulation of RNA biosynthetic process
JS609_RS17260	COG0840	transmembrane signaling receptor activity
JS609_RS17265	COG1174	glycine betaine transport
JS609_RS17270	COG1732	Glycine betaine
JS609_RS17275	COG1174	glycine betaine transport
JS609_RS17280	COG0517	IMP dehydrogenase activity
JS609_RS17280	COG1125	glycine betaine transport
JS609_RS17285	COG1510	regulation of RNA biosynthetic process
JS609_RS17290	COG1174	glycine betaine transport
JS609_RS17295	COG1732	Glycine betaine
JS609_RS17300	COG1174	glycine betaine transport
JS609_RS17305	COG1125	glycine betaine transport
JS609_RS17305	COG0517	IMP dehydrogenase activity
JS609_RS17310	COG1510	regulation of RNA biosynthetic process
JS609_RS17325	COG3064	Membrane
JS609_RS17330	COG4640	response to antibiotic
JS609_RS17335	COG0456	acetyltransferase
JS609_RS17340	COG0148	phosphopyruvate hydratase activity
JS609_RS17345	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JS609_RS17350	COG0149	triose-phosphate isomerase activity
JS609_RS17355	COG0126	phosphoglycerate kinase activity
JS609_RS17360	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JS609_RS17365	COG2390	Transcriptional regulator
JS609_RS17370	COG2814	Major facilitator Superfamily
JS609_RS17375	COG1609	Transcriptional regulator
JS609_RS17380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JS609_RS17385	COG0583	DNA-binding transcription factor activity
JS609_RS17390	COG0697	spore germination
JS609_RS17400	COG3858	chitin binding
JS609_RS17405	COG1556	Lactate utilization protein
JS609_RS17410	COG1139	Iron-sulfur cluster binding protein
JS609_RS17415	COG0247	lactate metabolic process
JS609_RS17420	COG2197	response regulator
JS609_RS17425	COG4585	Histidine kinase
JS609_RS17430	COG0842	Transport permease protein
JS609_RS17435	COG1131	(ABC) transporter
JS609_RS17440	COG0596	Alpha beta hydrolase
JS609_RS17445	COG2208	phosphoserine phosphatase activity
JS609_RS17450	COG3867	Arabinogalactan endo-beta-1,4-galactanase
JS609_RS17455	COG1874	Beta-galactosidase
JS609_RS17460	COG3833	ABC-type maltose transport systems, permease component
JS609_RS17465	COG1175	transmembrane transport
JS609_RS17470	COG2182	Extracellular solute-binding protein
JS609_RS17475	COG1609	Transcriptional regulator
JS609_RS17480	COG2186	Transcriptional regulator
JS609_RS17485	COG1620	l-lactate permease
JS609_RS17490	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
JS609_RS17500	COG5039	Polysaccharide pyruvyl transferase
JS609_RS17505	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JS609_RS17510	COG0110	maltose O-acetyltransferase activity
JS609_RS17515	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JS609_RS17520	COG2244	polysaccharide biosynthetic process
JS609_RS17525	COG1216	Glycosyl transferase, family 2
JS609_RS17530	COG5039	Polysaccharide pyruvyl transferase
JS609_RS17535	COG1216	Glycosyl transferase, family 2
JS609_RS17545	COG0438	transferase activity, transferring glycosyl groups
JS609_RS17550	COG1215	transferase activity, transferring glycosyl groups
JS609_RS17555	COG0438	transferase activity, transferring glycosyl groups
JS609_RS17560	COG1086	Polysaccharide biosynthesis protein
JS609_RS17565	COG0489	protein tyrosine kinase activity
JS609_RS17570	COG3944	biosynthesis protein
JS609_RS17575	COG1396	sequence-specific DNA binding
JS609_RS17580	COG2272	Belongs to the type-B carboxylesterase lipase family
JS609_RS17590	COG3479	Phenolic acid decarboxylase
JS609_RS17600	COG1794	racemase activity, acting on amino acids and derivatives
JS609_RS17605	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JS609_RS17610	COG1621	beta-fructofuranosidase activity
JS609_RS17615	COG1621	beta-fructofuranosidase activity
JS609_RS17620	COG0531	amino acid
JS609_RS17625	COG1309	transcriptional regulator
JS609_RS17630	COG2076	Multidrug Resistance protein
JS609_RS17635	COG2076	Multidrug Resistance protein
JS609_RS17645	COG0277	FAD linked oxidase domain protein
JS609_RS17650	COG3621	Patatin-like phospholipase
JS609_RS17660	COG0740	serine-type endopeptidase activity
JS609_RS17670	COG0366	Alpha amylase catalytic
JS609_RS17675	COG1554	hydrolase, family 65, central catalytic
JS609_RS17680	COG5521	maltodextrose utilization protein MalA
JS609_RS17685	COG3833	ABC-type maltose transport systems, permease component
JS609_RS17690	COG1175	transmembrane transport
JS609_RS17695	COG2182	Extracellular solute-binding protein
JS609_RS17700	COG0366	Alpha amylase catalytic
JS609_RS17705	COG1609	Transcriptional regulator
JS609_RS17710	COG1611	Belongs to the LOG family
JS609_RS17715	COG1694	Mazg nucleotide pyrophosphohydrolase
JS609_RS17720	COG0659	secondary active sulfate transmembrane transporter activity
JS609_RS17725	COG0288	reversible hydration of carbon dioxide
JS609_RS17730	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JS609_RS17735	COG0577	efflux transmembrane transporter activity
JS609_RS17740	COG1136	(ABC) transporter
JS609_RS17745	COG5002	protein histidine kinase activity
JS609_RS17750	COG0745	RESPONSE REGULATOR receiver
JS609_RS17760	COG2162	N-hydroxyarylamine O-acetyltransferase activity
JS609_RS17765	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JS609_RS17770	COG1481	regulation of sporulation
JS609_RS17775	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JS609_RS17780	COG1660	Displays ATPase and GTPase activities
JS609_RS17785	COG1051	belongs to the nudix hydrolase family
JS609_RS17790	COG0492	ferredoxin-NADP+ reductase activity
JS609_RS17795	COG3883	PFAM NLP P60 protein
JS609_RS17795	COG0791	NLP P60 protein
JS609_RS17800	COG0457	Tetratricopeptide repeat
JS609_RS17805	COG1132	(ABC) transporter
JS609_RS17825	COG0140	phosphoribosyl-ATP diphosphatase activity
JS609_RS17825	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JS609_RS17830	COG0107	imidazoleglycerol-phosphate synthase activity
JS609_RS17835	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JS609_RS17840	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JS609_RS17845	COG0131	Imidazoleglycerol-phosphate dehydratase
JS609_RS17850	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JS609_RS17855	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JS609_RS17860	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
JS609_RS17865	COG4990	cell redox homeostasis
JS609_RS17870	COG5297	Belongs to the glycosyl hydrolase family 6
JS609_RS17875	COG0110	maltose O-acetyltransferase activity
JS609_RS17880	COG0546	phosphoglycolate phosphatase activity
JS609_RS17885	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
JS609_RS17890	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JS609_RS17895	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JS609_RS17900	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JS609_RS17905	COG0363	glucosamine-6-phosphate deaminase activity
JS609_RS17910	COG2188	Transcriptional regulator
JS609_RS17915	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JS609_RS17920	COG1846	Transcriptional regulator
JS609_RS17925	COG2124	cytochrome p450
JS609_RS17935	COG1846	Transcriptional regulator
JS609_RS17940	COG2814	Major facilitator Superfamily
JS609_RS17945	COG1950	PFAM Membrane protein of
JS609_RS17950	COG1983	PspC domain protein
JS609_RS17955	COG3595	metallopeptidase activity
JS609_RS17970	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JS609_RS17980	COG0556	nucleotide-excision repair
JS609_RS17985	COG4897	Protein conserved in bacteria
JS609_RS17990	COG3848	Pyruvate phosphate dikinase
JS609_RS17990	COG0574	Belongs to the PEP-utilizing enzyme family
JS609_RS17995	COG1309	transcriptional regulator
JS609_RS18000	COG2814	Major facilitator Superfamily
JS609_RS18005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JS609_RS18015	COG3409	Peptidoglycan-binding domain 1 protein
JS609_RS18015	COG0793	Belongs to the peptidase S41A family
JS609_RS18020	COG2177	Part of the ABC transporter FtsEX involved in
JS609_RS18025	COG2884	Cell division ATP-binding protein ftsE
JS609_RS18050	COG0494	nUDIX hydrolase
JS609_RS18055	COG1011	Hydrolase
JS609_RS18085	COG4555	ABC transporter
JS609_RS18095	COG2010	Cytochrome c
JS609_RS18100	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JS609_RS18110	COG0653	protein targeting
JS609_RS18115	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JS609_RS18130	COG1516	flagellar protein fliS
JS609_RS18135	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
JS609_RS18140	COG1334	flagellar protein FlaG
JS609_RS18145	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JS609_RS18150	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
JS609_RS18155	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
JS609_RS18165	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JS609_RS18170	COG4786	Flagellar basal body rod
JS609_RS18170	COG1256	bacterial-type flagellum assembly
JS609_RS18175	COG3418	PFAM FlgN family protein
JS609_RS18180	COG2747	anti-sigma28 factor FlgM
JS609_RS18190	COG1040	competence protein
JS609_RS18200	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JS609_RS18205	COG1307	EDD domain protein, DegV family
JS609_RS18210	COG2197	response regulator
JS609_RS18215	COG4585	Histidine kinase
JS609_RS18220	COG1739	Uncharacterized protein family UPF0029
JS609_RS18225	COG1316	TRANSCRIPTIONal
JS609_RS18230	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JS609_RS18235	COG0438	transferase activity, transferring glycosyl groups
JS609_RS18240	COG1215	transferase activity, transferring glycosyl groups
JS609_RS18245	COG3206	protein involved in exopolysaccharide biosynthesis
JS609_RS18250	COG3307	-O-antigen
JS609_RS18255	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JS609_RS18260	COG0438	transferase activity, transferring glycosyl groups
JS609_RS18260	COG0297	glycogen (starch) synthase activity
JS609_RS18265	COG2244	polysaccharide biosynthetic process
JS609_RS18275	COG2247	cell wall binding repeat
JS609_RS18275	COG0860	N-Acetylmuramoyl-L-alanine amidase
JS609_RS18280	COG2247	cell wall binding repeat
JS609_RS18280	COG2385	sporulation resulting in formation of a cellular spore
JS609_RS18290	COG1316	TRANSCRIPTIONal
JS609_RS18295	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JS609_RS18300	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JS609_RS18315	COG1215	transferase activity, transferring glycosyl groups
JS609_RS18315	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JS609_RS18320	COG0463	Glycosyl transferase, family 2
JS609_RS18345	COG1134	teichoic acid transport
JS609_RS18350	COG1682	transport, permease protein
JS609_RS18355	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JS609_RS18360	COG0438	transferase activity, transferring glycosyl groups
JS609_RS18365	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JS609_RS18370	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
JS609_RS18375	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JS609_RS18385	COG4193	domain, Protein
JS609_RS18390	COG1482	cell wall glycoprotein biosynthetic process
JS609_RS18395	COG0697	spore germination
JS609_RS18400	COG0814	amino acid
JS609_RS18410	COG2814	Major facilitator Superfamily
JS609_RS18415	COG1316	TRANSCRIPTIONal
JS609_RS18420	COG0561	phosphatase activity
JS609_RS18425	COG0791	NLP P60 protein
JS609_RS18435	COG2843	Capsule synthesis protein
JS609_RS18445	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JS609_RS18450	COG1609	Transcriptional regulator
JS609_RS18455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JS609_RS18460	COG1869	D-ribose catabolic process
JS609_RS18465	COG1129	ABC transporter
JS609_RS18470	COG1172	Belongs to the binding-protein-dependent transport system permease family
JS609_RS18475	COG1879	ABC-type sugar transport system periplasmic component
JS609_RS18480	COG3103	Sh3 type 3 domain protein
JS609_RS18490	COG2249	NAD(P)H dehydrogenase (quinone) activity
JS609_RS18495	COG3527	Alpha-acetolactate decarboxylase
JS609_RS18500	COG0028	Belongs to the TPP enzyme family
JS609_RS18505	COG0583	DNA-binding transcription factor activity
JS609_RS18510	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JS609_RS18525	COG5337	Spore coat protein CotH
JS609_RS18535	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JS609_RS18545	COG0405	Gamma-glutamyltransferase
JS609_RS18550	COG1522	sequence-specific DNA binding
JS609_RS18555	COG2059	Chromate
JS609_RS18560	COG2059	Chromate
JS609_RS18570	COG0655	NAD(P)H dehydrogenase (quinone) activity
JS609_RS18575	COG0583	DNA-binding transcription factor activity
JS609_RS18580	COG1515	deoxyribonuclease V activity
JS609_RS18640	COG3878	Protein conserved in bacteria
JS609_RS18645	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JS609_RS18650	COG4464	protein tyrosine phosphatase activity
JS609_RS18655	COG0489	protein tyrosine kinase activity
JS609_RS18660	COG3944	biosynthesis protein
JS609_RS18670	COG4715	Zinc finger, swim domain protein
JS609_RS18675	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JS609_RS18680	COG0561	phosphatase activity
JS609_RS18685	COG1349	DNA-binding transcription factor activity
JS609_RS18690	COG0629	single-stranded DNA binding
JS609_RS18715	COG0745	RESPONSE REGULATOR receiver
JS609_RS18715	COG2972	Histidine kinase
JS609_RS18720	COG1970	mechanosensitive ion channel activity
JS609_RS18725	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JS609_RS18730	COG0457	Tetratricopeptide repeat
JS609_RS18735	COG4786	Flagellar basal body rod
JS609_RS18740	COG4786	Flagellar basal body rod
JS609_RS18745	COG1077	Cell shape determining protein MreB Mrl
JS609_RS18750	COG1609	Transcriptional regulator
JS609_RS18760	COG1846	Transcriptional regulator
JS609_RS18765	COG2814	Major facilitator Superfamily
JS609_RS18770	COG3420	alginic acid biosynthetic process
JS609_RS18775	COG1953	Uracil, thiamine, allantoin
JS609_RS18780	COG0477	Major facilitator Superfamily
JS609_RS18785	COG1335	isochorismatase
JS609_RS18795	COG0004	ammonium transporteR
JS609_RS18800	COG0347	Belongs to the P(II) protein family
JS609_RS18805	COG0671	phosphoesterase, PA-phosphatase related
JS609_RS18815	COG0739	heme binding
JS609_RS18820	COG1247	-acetyltransferase
JS609_RS18840	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JS609_RS18845	COG0789	Transcriptional regulator
JS609_RS18855	COG2910	NAD(P)H-binding
JS609_RS18860	COG1959	2 iron, 2 sulfur cluster binding
JS609_RS18865	COG0804	urea catabolic process
JS609_RS18870	COG0832	Belongs to the urease beta subunit family
JS609_RS18875	COG0831	urea catabolic process
JS609_RS18890	COG3237	CsbD-like
JS609_RS18895	COG1994	Peptidase M50
JS609_RS18900	COG0457	Tetratricopeptide repeat
JS609_RS18905	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JS609_RS18910	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JS609_RS18920	COG2304	oxidoreductase activity
JS609_RS18930	COG2304	oxidoreductase activity
JS609_RS18935	COG2385	sporulation resulting in formation of a cellular spore
JS609_RS18940	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JS609_RS18950	COG4836	Membrane
JS609_RS18960	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JS609_RS18965	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JS609_RS18970	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JS609_RS18975	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JS609_RS18980	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JS609_RS18985	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JS609_RS18995	COG0356	it plays a direct role in the translocation of protons across the membrane
JS609_RS19005	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JS609_RS19010	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JS609_RS19015	COG4475	Protein of unknown function (DUF436)
JS609_RS19020	COG0698	ribose 5-phosphate isomerase
JS609_RS19025	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JS609_RS19030	COG1971	Probably functions as a manganese efflux pump
JS609_RS19035	COG0009	L-threonylcarbamoyladenylate synthase
JS609_RS19040	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
JS609_RS19060	COG2890	protein-(glutamine-N5) methyltransferase activity
JS609_RS19065	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JS609_RS19070	COG0346	lactoylglutathione lyase activity
JS609_RS19075	COG0789	Transcriptional regulator
JS609_RS19080	COG0679	Auxin Efflux Carrier
JS609_RS19085	COG0281	malic enzyme
JS609_RS19090	COG1435	thymidine kinase activity
JS609_RS19100	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JS609_RS19110	COG1494	fructose-1,6-bisphosphatase
JS609_RS19115	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JS609_RS19120	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JS609_RS19125	COG0191	fructose-bisphosphate aldolase activity
JS609_RS19130	COG2204	response regulator
JS609_RS19135	COG4821	SIS domain
JS609_RS19140	COG0504	CTP synthase activity
JS609_RS19145	COG3343	RNA polymerase activity
JS609_RS19150	COG1960	acyl-CoA dehydrogenase activity
JS609_RS19155	COG0247	lactate metabolic process
JS609_RS19155	COG2181	nitrate reductase activity
JS609_RS19160	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JS609_RS19165	COG4294	response to UV
JS609_RS19175	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JS609_RS19180	COG1132	(ABC) transporter
JS609_RS19185	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JS609_RS19195	COG2181	nitrate reductase activity
JS609_RS19200	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
JS609_RS19205	COG1140	nitrate reductase beta subunit
JS609_RS19215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JS609_RS19225	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JS609_RS19230	COG2223	nitrite transmembrane transporter activity
JS609_RS19235	COG0018	arginyl-trna synthetase
JS609_RS19240	COG4506	Protein conserved in bacteria
JS609_RS19255	COG0535	radical SAM domain protein
JS609_RS19265	COG1131	(ABC) transporter
JS609_RS19270	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JS609_RS19275	COG0612	Peptidase, M16
JS609_RS19280	COG0612	Peptidase, M16
JS609_RS19290	COG3391	amine dehydrogenase activity
JS609_RS19295	COG3391	amine dehydrogenase activity
JS609_RS19300	COG0457	Tetratricopeptide repeat
JS609_RS19315	COG0010	Belongs to the arginase family
JS609_RS19320	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JS609_RS19325	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JS609_RS19335	COG1994	Peptidase M50
JS609_RS19340	COG1942	4-Oxalocrotonate Tautomerase
JS609_RS19345	COG1846	Transcriptional regulator
JS609_RS19350	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JS609_RS19355	COG0477	Major facilitator Superfamily
JS609_RS19360	COG1959	2 iron, 2 sulfur cluster binding
JS609_RS19365	COG3465	dGTPase activity
JS609_RS19370	COG1078	dGTPase activity
JS609_RS19375	COG4844	belongs to the
JS609_RS19385	COG0697	spore germination
JS609_RS19390	COG0095	Lipoate-protein ligase
JS609_RS19395	COG0583	DNA-binding transcription factor activity
JS609_RS19400	COG0280	phosphate acetyltransferase
JS609_RS19405	COG3253	May function as heme-dependent peroxidase
JS609_RS19410	COG1028	Short-chain dehydrogenase reductase Sdr
JS609_RS19415	COG0436	Aminotransferase
JS609_RS19420	COG2814	Major facilitator Superfamily
JS609_RS19425	COG0151	Belongs to the GarS family
JS609_RS19430	COG1028	Short-chain dehydrogenase reductase Sdr
JS609_RS19435	COG1917	Cupin 2, conserved barrel domain protein
JS609_RS19440	COG0077	Prephenate dehydratase
JS609_RS19445	COG2814	Major facilitator Superfamily
JS609_RS19450	COG0833	amino acid
JS609_RS19455	COG4187	Peptidase family M20/M25/M40
JS609_RS19460	COG1012	belongs to the aldehyde dehydrogenase family
JS609_RS19465	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JS609_RS19475	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
JS609_RS19480	COG1091	dTDP-4-dehydrorhamnose reductase activity
JS609_RS19485	COG1088	dTDP-glucose 4,6-dehydratase activity
JS609_RS19490	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JS609_RS19495	COG3980	spore coat polysaccharide biosynthesis protein
JS609_RS19500	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
JS609_RS19505	COG2089	acid synthase
JS609_RS19510	COG0456	acetyltransferase
JS609_RS19515	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JS609_RS19520	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JS609_RS19525	COG0463	Glycosyl transferase, family 2
JS609_RS19535	COG2363	Small membrane protein
JS609_RS19540	COG2233	PERMEase
JS609_RS19550	COG1012	belongs to the aldehyde dehydrogenase family
JS609_RS19555	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JS609_RS19560	COG1216	Glycosyl transferase, family 2
JS609_RS19575	COG1695	Transcriptional regulator
JS609_RS19580	COG0351	phosphomethylpyrimidine kinase
JS609_RS19590	COG1621	beta-fructofuranosidase activity
JS609_RS19595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JS609_RS19595	COG1263	PTS System
JS609_RS19600	COG2116	formate transmembrane transporter activity
JS609_RS19605	COG3711	transcriptional antiterminator
JS609_RS19615	COG1404	Belongs to the peptidase S8 family
JS609_RS19620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JS609_RS19625	COG0778	Nitroreductase
JS609_RS19630	COG0772	Belongs to the SEDS family
JS609_RS19640	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JS609_RS19650	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JS609_RS19655	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JS609_RS19660	COG2261	transglycosylase associated protein
JS609_RS19665	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
JS609_RS19670	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JS609_RS19675	COG2246	polysaccharide biosynthetic process
JS609_RS19680	COG1309	transcriptional regulator
JS609_RS19690	COG3162	membrane
JS609_RS19695	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JS609_RS19700	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JS609_RS19710	COG2822	iron ion transport
JS609_RS19715	COG0672	)-iron permease
JS609_RS19720	COG0352	thiamine-phosphate diphosphorylase activity
JS609_RS19725	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JS609_RS19730	COG0583	DNA-binding transcription factor activity
JS609_RS19735	COG1380	Effector of murein hydrolase LrgA
JS609_RS19740	COG1346	cytolysis
JS609_RS19745	COG2814	Major facilitator Superfamily
JS609_RS19750	COG4895	conserved protein (DUF2196)
JS609_RS19755	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JS609_RS19760	COG0346	lactoylglutathione lyase activity
JS609_RS19770	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JS609_RS19780	COG1263	PTS System
JS609_RS19780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JS609_RS19785	COG3711	transcriptional antiterminator
JS609_RS19790	COG1442	glycosyl transferase family 8
JS609_RS19795	COG5522	Integral membrane protein (intg_mem_TP0381)
JS609_RS19800	COG1846	Transcriptional regulator
JS609_RS19805	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JS609_RS19810	COG2234	aminopeptidase activity
JS609_RS19825	COG2814	Major facilitator Superfamily
JS609_RS19830	COG2357	RelA SpoT domain protein
JS609_RS19835	COG1575	Belongs to the MenA family. Type 1 subfamily
JS609_RS19850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JS609_RS19855	COG1696	Membrane protein involved in D-alanine export
JS609_RS19860	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JS609_RS19865	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JS609_RS19870	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
JS609_RS19875	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JS609_RS19880	COG1486	melibiose metabolic process
JS609_RS19885	COG1447	Phosphotransferase system cellobiose-specific component IIA
JS609_RS19890	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JS609_RS19895	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JS609_RS19900	COG3711	transcriptional antiterminator
JS609_RS19900	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JS609_RS19910	COG2094	Belongs to the DNA glycosylase MPG family
JS609_RS19915	COG0753	catalase activity
JS609_RS19920	COG2814	Major facilitator Superfamily
JS609_RS19925	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
JS609_RS19930	COG1131	(ABC) transporter
JS609_RS19950	COG1595	DNA-templated transcription, initiation
JS609_RS19955	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
JS609_RS19960	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JS609_RS19965	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JS609_RS19970	COG4988	ABC transporter
JS609_RS19975	COG1294	oxidase, subunit
JS609_RS19980	COG1271	oxidase subunit
JS609_RS19985	COG3493	citrate carrier protein
JS609_RS19990	COG0501	Belongs to the peptidase M48B family
JS609_RS20000	COG0726	polysaccharide deacetylase
JS609_RS20005	COG3842	ATPase activity
JS609_RS20010	COG2508	Transcriptional regulator
JS609_RS20015	COG1012	belongs to the aldehyde dehydrogenase family
JS609_RS20020	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JS609_RS20030	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JS609_RS20040	COG4585	Histidine kinase
JS609_RS20045	COG2197	response regulator
JS609_RS20050	COG2195	Cleaves the N-terminal amino acid of tripeptides
JS609_RS20065	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JS609_RS20070	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JS609_RS20075	COG1028	Short-chain dehydrogenase reductase Sdr
JS609_RS20080	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JS609_RS20085	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JS609_RS20090	COG2610	gluconate transmembrane transporter activity
JS609_RS20095	COG0500	methyltransferase
JS609_RS20100	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JS609_RS20115	COG0693	protein deglycase activity
JS609_RS20115	COG0753	catalase activity
JS609_RS20120	COG2851	Citrate transporter
JS609_RS20125	COG2273	Hydrolase Family 16
JS609_RS20130	COG3711	transcriptional antiterminator
JS609_RS20140	COG2270	Major facilitator Superfamily
JS609_RS20145	COG0513	Belongs to the DEAD box helicase family
JS609_RS20150	COG2755	lipolytic protein G-D-S-L family
JS609_RS20150	COG3401	FG-GAP repeat protein
JS609_RS20200	COG0697	spore germination
JS609_RS20215	COG0589	response to stress
JS609_RS20220	COG2723	6-phospho-beta-galactosidase activity
JS609_RS20225	COG2190	(PTS) system
JS609_RS20225	COG1263	PTS System
JS609_RS20225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JS609_RS20245	COG5444	nuclease activity
JS609_RS20260	COG3507	Belongs to the glycosyl hydrolase 43 family
JS609_RS20275	COG2986	histidine ammonia-lyase
JS609_RS20280	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
JS609_RS20285	COG1228	amidohydrolase
JS609_RS20290	COG0010	Belongs to the arginase family
JS609_RS20295	COG0833	amino acid
JS609_RS20300	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
JS609_RS20305	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JS609_RS20310	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JS609_RS20315	COG2390	Transcriptional regulator
JS609_RS20325	COG3192	ethanolamine utilization protein
JS609_RS20330	COG2079	MmgE PrpD family protein
JS609_RS20335	COG1473	amidohydrolase
JS609_RS20340	COG1126	abc transporter atp-binding protein
JS609_RS20345	COG0765	amino acid transport
JS609_RS20350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JS609_RS20355	COG0456	acetyltransferase
JS609_RS20360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JS609_RS20370	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
JS609_RS20375	COG0561	phosphatase activity
JS609_RS20405	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JS609_RS20410	COG5294	Protein conserved in bacteria
JS609_RS20415	COG0577	efflux transmembrane transporter activity
JS609_RS20420	COG1136	(ABC) transporter
JS609_RS20425	COG2205	protein histidine kinase activity
JS609_RS20430	COG0745	RESPONSE REGULATOR receiver
JS609_RS20435	COG0191	fructose-bisphosphate aldolase activity
JS609_RS20440	COG1082	Xylose isomerase domain protein TIM barrel
JS609_RS20445	COG1082	Xylose isomerase domain protein TIM barrel
JS609_RS20450	COG0673	inositol 2-dehydrogenase activity
JS609_RS20455	COG2814	Major facilitator Superfamily
JS609_RS20460	COG1082	Xylose isomerase domain protein TIM barrel
JS609_RS20465	COG3962	Belongs to the TPP enzyme family
JS609_RS20470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JS609_RS20475	COG3718	enzyme involved in inositol metabolism
JS609_RS20480	COG1012	belongs to the aldehyde dehydrogenase family
JS609_RS20485	COG1349	DNA-binding transcription factor activity
JS609_RS20490	COG0667	Aldo Keto reductase
JS609_RS20505	COG2814	Major facilitator Superfamily
JS609_RS20510	COG0326	Molecular chaperone. Has ATPase activity
JS609_RS20520	COG1028	Short-chain dehydrogenase reductase Sdr
JS609_RS20525	COG1309	transcriptional regulator
JS609_RS20530	COG1012	belongs to the aldehyde dehydrogenase family
JS609_RS20535	COG1714	RDD family
JS609_RS20540	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JS609_RS20550	COG1714	RDD family
JS609_RS20555	COG2311	Membrane
JS609_RS20560	COG1917	Cupin 2, conserved barrel domain protein
JS609_RS20565	COG1309	transcriptional regulator
JS609_RS20570	COG1028	Short-chain dehydrogenase reductase Sdr
JS609_RS20575	COG1846	Transcriptional regulator
JS609_RS20580	COG1380	Effector of murein hydrolase LrgA
JS609_RS20585	COG1346	cytolysis
JS609_RS20590	COG5039	Polysaccharide pyruvyl transferase
JS609_RS20600	COG1802	Transcriptional regulator
JS609_RS20605	COG1070	Carbohydrate kinase
JS609_RS20610	COG2610	gluconate transmembrane transporter activity
JS609_RS20615	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JS609_RS20620	COG0450	alkyl hydroperoxide reductase
JS609_RS20625	COG3634	alkyl hydroperoxide reductase activity
JS609_RS20630	COG2723	6-phospho-beta-galactosidase activity
JS609_RS20640	COG2188	Transcriptional regulator
JS609_RS20650	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
JS609_RS20685	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JS609_RS20700	COG1063	alcohol dehydrogenase
JS609_RS20720	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
JS609_RS20725	COG0456	acetyltransferase
JS609_RS20730	COG0457	Tetratricopeptide repeat
JS609_RS20740	COG0010	Belongs to the arginase family
JS609_RS20745	COG0833	amino acid
JS609_RS20750	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JS609_RS20755	COG3829	transcription factor binding
JS609_RS20760	COG5002	protein histidine kinase activity
JS609_RS20765	COG0745	RESPONSE REGULATOR receiver
JS609_RS20785	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JS609_RS20790	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JS609_RS20795	COG4853	Protein conserved in bacteria
JS609_RS20800	COG4863	YycH protein
JS609_RS20805	COG5002	protein histidine kinase activity
JS609_RS20810	COG0745	RESPONSE REGULATOR receiver
JS609_RS20840	COG0346	lactoylglutathione lyase activity
JS609_RS20845	COG0305	Participates in initiation and elongation during chromosome replication
JS609_RS20860	COG3093	addiction module antidote protein HigA
JS609_RS20865	COG2807	transmembrane transport
JS609_RS20870	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JS609_RS20875	COG0359	binds to the 23S rRNA
JS609_RS20880	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
JS609_RS20885	COG4241	membrane
JS609_RS20895	COG5577	PFAM Coat F domain
JS609_RS20900	COG1733	regulation of RNA biosynthetic process
JS609_RS20905	COG1227	inorganic diphosphatase activity
JS609_RS20915	COG2271	Major facilitator Superfamily
JS609_RS20920	COG4978	Transcriptional regulator
JS609_RS20920	COG0789	Transcriptional regulator
JS609_RS20930	COG4319	ketosteroid isomerase
JS609_RS20935	COG1357	PFAM Pentapeptide repeats (8 copies)
JS609_RS20940	COG2814	Major facilitator Superfamily
JS609_RS20945	COG0583	DNA-binding transcription factor activity
JS609_RS20950	COG2153	protein acetylation
JS609_RS20965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JS609_RS20970	COG1846	Transcriptional regulator
JS609_RS20975	COG2153	protein acetylation
JS609_RS20980	COG2364	Membrane
JS609_RS20985	COG0456	acetyltransferase
JS609_RS20990	COG2315	Protein conserved in bacteria
JS609_RS20995	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JS609_RS21005	COG2814	Major facilitator Superfamily
JS609_RS21015	COG1331	Highly conserved protein containing a thioredoxin domain
JS609_RS21020	COG0789	Transcriptional regulator
JS609_RS21025	COG0697	spore germination
JS609_RS21030	COG1331	Highly conserved protein containing a thioredoxin domain
JS609_RS21035	COG1266	CAAX protease self-immunity
JS609_RS21040	COG2814	Major facilitator Superfamily
JS609_RS21040	COG0477	Major facilitator Superfamily
JS609_RS21045	COG0110	maltose O-acetyltransferase activity
JS609_RS21050	COG0346	lactoylglutathione lyase activity
JS609_RS21055	COG1609	Transcriptional regulator
JS609_RS21060	COG0708	Exodeoxyribonuclease III
JS609_RS21065	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JS609_RS21070	COG0629	single-stranded DNA binding
JS609_RS21075	COG0360	Binds together with S18 to 16S ribosomal RNA
JS609_RS21080	COG0012	GTP binding
JS609_RS21085	COG0243	molybdopterin cofactor binding
JS609_RS21090	COG4481	Protein conserved in bacteria
JS609_RS21095	COG3949	Membrane
JS609_RS21105	COG1475	DNA binding
JS609_RS21110	COG1192	Involved in chromosome partitioning
JS609_RS21120	COG1475	DNA binding
JS609_RS21125	COG0357	Ribosomal RNA small subunit methyltransferase G
JS609_RS21130	COG0445	tRNA wobble uridine modification
JS609_RS21135	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JS609_RS21140	COG1847	R3H domain protein
JS609_RS21145	COG0706	membrane insertase activity
JS609_RS21150	COG0594	ribonuclease P activity
JS609_RS21160	COG1020	D-alanine [D-alanyl carrier protein] ligase activity