locus-tag	class	description
BSK2_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BSK2_RS00010	COG0592	DNA-directed DNA polymerase activity
BSK2_RS00015	COG2501	S4 domain
BSK2_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BSK2_RS00030	COG0187	DNA topoisomerase II activity
BSK2_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BSK2_RS00070	COG0516	GMP reductase activity
BSK2_RS00070	COG0517	IMP dehydrogenase activity
BSK2_RS00075	COG1686	Belongs to the peptidase S11 family
BSK2_RS00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BSK2_RS00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BSK2_RS00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BSK2_RS00100	COG1428	Deoxynucleoside kinase
BSK2_RS00105	COG1428	Deoxynucleoside kinase
BSK2_RS00110	COG3858	chitin binding
BSK2_RS00110	COG1388	LysM domain
BSK2_RS00115	COG1335	isochorismatase
BSK2_RS00120	COG0590	tRNA wobble adenosine to inosine editing
BSK2_RS00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BSK2_RS00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BSK2_RS00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BSK2_RS00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
BSK2_RS00190	COG3853	Toxic anion resistance protein (TelA)
BSK2_RS00195	COG1982	Orn Lys Arg decarboxylase major
BSK2_RS00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BSK2_RS00205	COG3870	Protein conserved in bacteria
BSK2_RS00210	COG1728	Protein conserved in bacteria
BSK2_RS00215	COG0470	DNA polymerase III
BSK2_RS00220	COG1774	PSP1 C-terminal conserved region
BSK2_RS00225	COG4467	Involved in initiation control of chromosome replication
BSK2_RS00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BSK2_RS00235	COG2827	Endonuclease containing a URI domain
BSK2_RS00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BSK2_RS00245	COG2002	toxin-antitoxin pair type II binding
BSK2_RS00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BSK2_RS00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BSK2_RS00255	COG0084	hydrolase, TatD family'
BSK2_RS00260	COG3584	3D domain protein
BSK2_RS00260	COG3583	domain protein
BSK2_RS00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BSK2_RS00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BSK2_RS00280	COG4466	Protein conserved in bacteria
BSK2_RS00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BSK2_RS00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BSK2_RS00300	COG0251	oxidation-reduction process
BSK2_RS00305	COG2088	sporulation resulting in formation of a cellular spore
BSK2_RS00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BSK2_RS00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BSK2_RS00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BSK2_RS00325	COG0193	aminoacyl-tRNA hydrolase activity
BSK2_RS00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BSK2_RS00340	COG2002	toxin-antitoxin pair type II binding
BSK2_RS00345	COG2244	polysaccharide biosynthetic process
BSK2_RS00350	COG3956	TIGRFAM MazG family protein
BSK2_RS00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BSK2_RS00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BSK2_RS00375	COG1098	S1 RNA binding domain
BSK2_RS00390	COG2208	phosphoserine phosphatase activity
BSK2_RS00395	COG2304	oxidoreductase activity
BSK2_RS00400	COG0515	serine threonine protein kinase
BSK2_RS00405	COG0037	tRNA processing
BSK2_RS00410	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BSK2_RS00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BSK2_RS00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BSK2_RS00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BSK2_RS00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BSK2_RS00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BSK2_RS00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BSK2_RS00445	COG0512	Glutamine amidotransferase of anthranilate synthase
BSK2_RS00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BSK2_RS00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BSK2_RS00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BSK2_RS00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BSK2_RS00470	COG1396	sequence-specific DNA binding
BSK2_RS00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BSK2_RS00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BSK2_RS00560	COG4463	regulation of RNA biosynthetic process
BSK2_RS00565	COG3880	PFAM UvrB UvrC protein
BSK2_RS00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BSK2_RS00575	COG0542	response to heat
BSK2_RS00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BSK2_RS00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BSK2_RS00590	COG4956	integral membrane protein (PIN domain superfamily)
BSK2_RS00595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BSK2_RS00600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BSK2_RS00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BSK2_RS00615	COG1045	serine acetyltransferase
BSK2_RS00620	COG0215	cysteine-tRNA ligase activity
BSK2_RS00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BSK2_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BSK2_RS00635	COG3688	RNA-binding protein containing a PIN domain
BSK2_RS00640	COG1595	DNA-templated transcription, initiation
BSK2_RS00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BSK2_RS00655	COG0250	Participates in transcription elongation, termination and antitermination
BSK2_RS00665	COG0081	regulation of translation
BSK2_RS00670	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BSK2_RS00680	COG2813	Specifically methylates the guanine in position
BSK2_RS00685	COG0085	RNA polymerase activity
BSK2_RS00690	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BSK2_RS00695	COG1358	cellular component organization or biogenesis
BSK2_RS00700	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BSK2_RS00705	COG0049	tRNA binding
BSK2_RS00710	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BSK2_RS00715	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BSK2_RS00720	COG0596	Alpha beta hydrolase
BSK2_RS00730	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BSK2_RS00735	COG0088	Forms part of the polypeptide exit tunnel
BSK2_RS00745	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BSK2_RS00765	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BSK2_RS00775	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BSK2_RS00780	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BSK2_RS00790	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BSK2_RS00800	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BSK2_RS00805	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BSK2_RS00810	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BSK2_RS00815	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BSK2_RS00825	COG0200	Binds to the 23S rRNA
BSK2_RS00830	COG0201	protein transport
BSK2_RS00835	COG0563	adenylate kinase activity
BSK2_RS00840	COG0024	Methionine aminopeptidase
BSK2_RS00845	COG2163	COG2163 Ribosomal protein L14E L6E L27E
BSK2_RS00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BSK2_RS00860	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BSK2_RS00865	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BSK2_RS00870	COG0202	RNA polymerase activity
BSK2_RS00875	COG0203	ribosomal protein L17
BSK2_RS00880	COG1122	ATPase activity
BSK2_RS00885	COG1122	ATPase activity
BSK2_RS00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BSK2_RS00895	COG0101	tRNA pseudouridine synthase activity
BSK2_RS00900	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BSK2_RS00905	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BSK2_RS00910	COG2226	methyltransferase
BSK2_RS00920	COG0860	N-Acetylmuramoyl-L-alanine amidase
BSK2_RS00925	COG0489	protein tyrosine kinase activity
BSK2_RS00935	COG2194	sulfuric ester hydrolase activity
BSK2_RS00940	COG0726	polysaccharide deacetylase
BSK2_RS01025	COG0659	secondary active sulfate transmembrane transporter activity
BSK2_RS01030	COG0385	Bile acid
BSK2_RS01035	COG2819	hydrolase of the alpha beta superfamily
BSK2_RS01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BSK2_RS01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BSK2_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BSK2_RS01055	COG2207	Transcriptional regulator
BSK2_RS01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BSK2_RS01060	COG3876	Protein conserved in bacteria
BSK2_RS01065	COG1472	Belongs to the glycosyl hydrolase 3 family
BSK2_RS01070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BSK2_RS01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BSK2_RS01075	COG1263	PTS System
BSK2_RS01080	COG1737	Transcriptional regulator
BSK2_RS01085	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BSK2_RS01090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BSK2_RS01095	COG1683	Conserved Protein
BSK2_RS01125	COG1595	DNA-templated transcription, initiation
BSK2_RS01130	COG5662	AntiSigma factor
BSK2_RS01135	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BSK2_RS01140	COG4856	YbbR-like protein
BSK2_RS01145	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BSK2_RS01150	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BSK2_RS01155	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BSK2_RS01160	COG2169	Transcriptional regulator
BSK2_RS01165	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BSK2_RS01170	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BSK2_RS01175	COG3002	Belongs to the UPF0753 family
BSK2_RS01180	COG0288	reversible hydration of carbon dioxide
BSK2_RS01190	COG5609	conserved protein (DUF2294)
BSK2_RS01200	COG0640	Transcriptional regulator
BSK2_RS01205	COG2814	Major facilitator Superfamily
BSK2_RS01225	COG1136	(ABC) transporter
BSK2_RS01250	COG1113	amino acid transport
BSK2_RS01265	COG2602	Beta-lactamase
BSK2_RS01270	COG2124	cytochrome p450
BSK2_RS01280	COG0531	amino acid
BSK2_RS01285	COG0584	glycerophosphoryl diester phosphodiesterase
BSK2_RS01290	COG2271	Major facilitator Superfamily
BSK2_RS01305	COG0456	acetyltransferase
BSK2_RS01305	COG1846	Transcriptional regulator
BSK2_RS01310	COG2271	Major facilitator Superfamily
BSK2_RS01315	COG0697	spore germination
BSK2_RS01320	COG2207	Transcriptional regulator
BSK2_RS01320	COG1917	Cupin 2, conserved barrel domain protein
BSK2_RS01325	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BSK2_RS01330	COG3591	Belongs to the peptidase S1B family
BSK2_RS01340	COG0596	Alpha beta hydrolase
BSK2_RS01345	COG1183	phosphatidylcholine synthase activity
BSK2_RS01350	COG0586	Pfam SNARE associated Golgi protein
BSK2_RS01355	COG0688	phosphatidylethanolamine metabolic process
BSK2_RS01365	COG2312	Erythromycin esterase
BSK2_RS01370	COG2207	Transcriptional regulator
BSK2_RS01375	COG1054	Belongs to the UPF0176 family
BSK2_RS01380	COG1301	dicarboxylic acid transport
BSK2_RS01385	COG1263	PTS System
BSK2_RS01385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BSK2_RS01385	COG2190	(PTS) system
BSK2_RS01390	COG0363	glucosamine-6-phosphate deaminase activity
BSK2_RS01395	COG2188	Transcriptional regulator
BSK2_RS01405	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BSK2_RS01410	COG0833	amino acid
BSK2_RS01415	COG2040	homocysteine
BSK2_RS01425	COG1115	amino acid carrier protein
BSK2_RS01430	COG2066	Belongs to the glutaminase family
BSK2_RS01435	COG4191	Histidine kinase
BSK2_RS01440	COG0784	Response regulator, receiver
BSK2_RS01445	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BSK2_RS01450	COG1012	belongs to the aldehyde dehydrogenase family
BSK2_RS01455	COG2271	Major facilitator Superfamily
BSK2_RS01460	COG4948	Mandelate Racemase Muconate Lactonizing
BSK2_RS01465	COG2186	Transcriptional regulator
BSK2_RS01470	COG2721	sulfolactate sulfo-lyase activity
BSK2_RS01480	COG3173	Aminoglycoside phosphotransferase
BSK2_RS01490	COG0697	spore germination
BSK2_RS01495	COG0745	RESPONSE REGULATOR receiver
BSK2_RS01500	COG2205	protein histidine kinase activity
BSK2_RS01505	COG1131	(ABC) transporter
BSK2_RS01520	COG3773	Cell wall hydrolase
BSK2_RS01525	COG2304	oxidoreductase activity
BSK2_RS01535	COG3540	Alkaline phosphatase
BSK2_RS01540	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BSK2_RS01545	COG0805	protein transport
BSK2_RS01550	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BSK2_RS01560	COG0477	Major facilitator Superfamily
BSK2_RS01565	COG1309	transcriptional regulator
BSK2_RS01570	COG0252	asparaginase activity
BSK2_RS01575	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BSK2_RS01580	COG1714	RDD family
BSK2_RS01585	COG3012	SEC-C Motif Domain Protein
BSK2_RS01585	COG1405	negative regulation of cell septum assembly
BSK2_RS01590	COG3290	protein histidine kinase activity
BSK2_RS01595	COG3279	Response regulator of the LytR AlgR family
BSK2_RS01600	COG4555	ABC transporter
BSK2_RS01605	COG1668	transmembrane transport
BSK2_RS01610	COG0667	Aldo Keto reductase
BSK2_RS01620	COG1595	DNA-templated transcription, initiation
BSK2_RS01630	COG1595	DNA-templated transcription, initiation
BSK2_RS01635	COG1876	peptidase activity
BSK2_RS01640	COG0457	Tetratricopeptide repeat
BSK2_RS01645	COG1028	Short-chain dehydrogenase reductase Sdr
BSK2_RS01650	COG0366	Alpha amylase catalytic
BSK2_RS01655	COG0803	Belongs to the bacterial solute-binding protein 9 family
BSK2_RS01660	COG1121	(ABC) transporter
BSK2_RS01665	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BSK2_RS01670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BSK2_RS01675	COG2310	stress, protein
BSK2_RS01680	COG2310	stress, protein
BSK2_RS01685	COG2310	stress, protein
BSK2_RS01690	COG0861	Integral membrane protein TerC family
BSK2_RS01700	COG3853	Toxic anion resistance protein (TelA)
BSK2_RS01705	COG0477	Major facilitator Superfamily
BSK2_RS01710	COG2814	Major facilitator Superfamily
BSK2_RS01715	COG0640	Transcriptional regulator
BSK2_RS01720	COG4175	Glycine betaine
BSK2_RS01720	COG0517	IMP dehydrogenase activity
BSK2_RS01725	COG4176	ABC-type proline glycine betaine transport system permease component
BSK2_RS01730	COG2113	Glycine betaine
BSK2_RS01735	COG1473	amidohydrolase
BSK2_RS01740	COG1288	antiporter activity
BSK2_RS01750	COG0366	Alpha amylase catalytic
BSK2_RS01755	COG0039	L-malate dehydrogenase activity
BSK2_RS01760	COG1620	l-lactate permease
BSK2_RS01765	COG2814	Major facilitator Superfamily
BSK2_RS01770	COG1846	Transcriptional regulator
BSK2_RS01775	COG1280	lysine exporter protein (LysE YggA)
BSK2_RS01780	COG3403	YqcI/YcgG family
BSK2_RS01785	COG1113	amino acid transport
BSK2_RS01790	COG3665	Urea carboxylase-associated protein
BSK2_RS01795	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BSK2_RS01800	COG1660	Displays ATPase and GTPase activities
BSK2_RS01805	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BSK2_RS01810	COG2226	methyltransferase
BSK2_RS01815	COG0583	DNA-binding transcription factor activity
BSK2_RS01820	COG3458	cephalosporin-C deacetylase activity
BSK2_RS01825	COG3541	Predicted nucleotidyltransferase
BSK2_RS01830	COG0506	proline dehydrogenase activity
BSK2_RS01835	COG1012	belongs to the aldehyde dehydrogenase family
BSK2_RS01840	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BSK2_RS01845	COG2508	Transcriptional regulator
BSK2_RS01850	COG3689	TIGRFAM TIGR03943 family protein
BSK2_RS01855	COG0701	Predicted permease
BSK2_RS01860	COG2267	carboxylic ester hydrolase activity
BSK2_RS01865	COG0492	ferredoxin-NADP+ reductase activity
BSK2_RS01870	COG1587	Uroporphyrinogen-III synthase
BSK2_RS01870	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BSK2_RS01875	COG2146	nitrite reductase [NAD(P)H] activity
BSK2_RS01880	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BSK2_RS01885	COG0243	molybdopterin cofactor binding
BSK2_RS01890	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BSK2_RS01895	COG2223	nitrite transmembrane transporter activity
BSK2_RS01900	COG1469	GTP cyclohydrolase I activity
BSK2_RS01905	COG1376	ErfK ybiS ycfS ynhG family protein
BSK2_RS01910	COG0523	cobalamin synthesis protein
BSK2_RS01915	COG0765	amino acid transport
BSK2_RS01920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSK2_RS01925	COG1714	RDD family
BSK2_RS01935	COG1846	Transcriptional regulator
BSK2_RS01945	COG3842	ATPase activity
BSK2_RS01950	COG2723	6-phospho-beta-galactosidase activity
BSK2_RS01960	COG3209	COG3209 Rhs family protein
BSK2_RS01965	COG0840	transmembrane signaling receptor activity
BSK2_RS01965	COG3290	protein histidine kinase activity
BSK2_RS01970	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BSK2_RS01975	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BSK2_RS01980	COG1733	regulation of RNA biosynthetic process
BSK2_RS01985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BSK2_RS01990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BSK2_RS01995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BSK2_RS02000	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
BSK2_RS02005	COG2814	Major facilitator Superfamily
BSK2_RS02015	COG0697	spore germination
BSK2_RS02020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BSK2_RS02030	COG2364	Membrane
BSK2_RS02040	COG1126	abc transporter atp-binding protein
BSK2_RS02045	COG0765	amino acid transport
BSK2_RS02050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSK2_RS02055	COG0583	DNA-binding transcription factor activity
BSK2_RS02060	COG0163	prenyltransferase activity
BSK2_RS02065	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BSK2_RS02080	COG0596	Alpha beta hydrolase
BSK2_RS02085	COG3104	oligopeptide transport
BSK2_RS02090	COG5434	Belongs to the glycosyl hydrolase 28 family
BSK2_RS02100	COG0697	spore germination
BSK2_RS02110	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BSK2_RS02115	COG1136	(ABC) transporter
BSK2_RS02120	COG0577	efflux transmembrane transporter activity
BSK2_RS02125	COG0745	RESPONSE REGULATOR receiver
BSK2_RS02130	COG5002	protein histidine kinase activity
BSK2_RS02130	COG3850	Histidine kinase
BSK2_RS02135	COG0457	Tetratricopeptide repeat
BSK2_RS02155	COG0527	aspartate kinase activity
BSK2_RS02160	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BSK2_RS02165	COG4605	iron ion homeostasis
BSK2_RS02170	COG4604	ABC transporter, ATP-binding protein
BSK2_RS02175	COG4607	ABC-type enterochelin transport system periplasmic component
BSK2_RS02180	COG2814	Major facilitator Superfamily
BSK2_RS02185	COG1309	transcriptional regulator
BSK2_RS02190	COG0778	Nitroreductase
BSK2_RS02195	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BSK2_RS02200	COG0640	Transcriptional regulator
BSK2_RS02205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BSK2_RS02210	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BSK2_RS02215	COG1012	belongs to the aldehyde dehydrogenase family
BSK2_RS02220	COG4975	Glucose uptake
BSK2_RS02225	COG1028	Short-chain dehydrogenase reductase Sdr
BSK2_RS02230	COG4549	nuclear export factor GLE1
BSK2_RS02235	COG1276	copper resistance
BSK2_RS02235	COG2372	response to copper ion
BSK2_RS02240	COG1349	DNA-binding transcription factor activity
BSK2_RS02250	COG2213	PTS system mannitol-specific
BSK2_RS02255	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BSK2_RS02260	COG0246	Mannitol dehydrogenase
BSK2_RS02265	COG0473	3-isopropylmalate dehydrogenase activity
BSK2_RS02275	COG0412	Dienelactone hydrolase
BSK2_RS02280	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BSK2_RS02290	COG0561	phosphatase activity
BSK2_RS02295	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BSK2_RS02300	COG1914	H( )-stimulated, divalent metal cation uptake system
BSK2_RS02305	COG4336	lyase activity
BSK2_RS02310	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BSK2_RS02315	COG1984	allophanate hydrolase subunit 2
BSK2_RS02320	COG1414	Transcriptional regulator
BSK2_RS02325	COG2755	lipolytic protein G-D-S-L family
BSK2_RS02335	COG2329	Antibiotic biosynthesis monooxygenase
BSK2_RS02340	COG0768	penicillin binding
BSK2_RS02345	COG4989	oxidoreductase activity
BSK2_RS02350	COG3711	transcriptional antiterminator
BSK2_RS02355	COG0318	PFAM AMP-dependent synthetase and ligase
BSK2_RS02360	COG2226	methyltransferase
BSK2_RS02365	COG1028	Short-chain dehydrogenase reductase Sdr
BSK2_RS02370	COG1917	Cupin 2, conserved barrel domain protein
BSK2_RS02375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BSK2_RS02380	COG3871	stress protein (general stress protein 26)
BSK2_RS02390	COG2814	Major facilitator Superfamily
BSK2_RS02395	COG1522	sequence-specific DNA binding
BSK2_RS02400	COG0551	DNA topoisomerase type I activity
BSK2_RS02400	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BSK2_RS02405	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BSK2_RS02410	COG3706	GGDEF domain
BSK2_RS02415	COG5298	Protein conserved in bacteria
BSK2_RS02420	COG1215	transferase activity, transferring glycosyl groups
BSK2_RS02430	COG0531	amino acid
BSK2_RS02440	COG0028	Belongs to the TPP enzyme family
BSK2_RS02455	COG1914	H( )-stimulated, divalent metal cation uptake system
BSK2_RS02460	COG2261	transglycosylase associated protein
BSK2_RS02465	COG4876	unkown
BSK2_RS02470	COG2217	Heavy metal translocating P-type atpase
BSK2_RS02475	COG3729	General stress protein
BSK2_RS02480	COG0662	Cupin 2, conserved barrel domain protein
BSK2_RS02485	COG2329	Antibiotic biosynthesis monooxygenase
BSK2_RS02490	COG3546	catalase activity
BSK2_RS02495	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BSK2_RS02500	COG3290	protein histidine kinase activity
BSK2_RS02505	COG4565	transcriptional regulatory protein
BSK2_RS02510	COG1301	dicarboxylic acid transport
BSK2_RS02515	COG0628	permease
BSK2_RS02520	COG1131	(ABC) transporter
BSK2_RS02525	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BSK2_RS02535	COG1960	acyl-CoA dehydrogenase activity
BSK2_RS02555	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BSK2_RS02560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSK2_RS02565	COG1181	Belongs to the D-alanine--D-alanine ligase family
BSK2_RS02570	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BSK2_RS02580	COG0513	Belongs to the DEAD box helicase family
BSK2_RS02585	COG3402	PFAM membrane-flanked domain
BSK2_RS02590	COG3428	Bacterial PH domain
BSK2_RS02595	COG0705	Rhomboid family
BSK2_RS02600	COG0736	holo-[acyl-carrier-protein] synthase activity
BSK2_RS02605	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BSK2_RS02610	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BSK2_RS02615	COG0864	Transcriptional regulator
BSK2_RS02620	COG2337	Toxic component of a toxin-antitoxin (TA) module
BSK2_RS02625	COG1366	Belongs to the anti-sigma-factor antagonist family
BSK2_RS02630	COG1366	Belongs to the anti-sigma-factor antagonist family
BSK2_RS02635	COG2172	sigma factor antagonist activity
BSK2_RS02640	COG2208	phosphoserine phosphatase activity
BSK2_RS02645	COG1366	Belongs to the anti-sigma-factor antagonist family
BSK2_RS02650	COG2172	sigma factor antagonist activity
BSK2_RS02655	COG1191	sigma factor activity
BSK2_RS02660	COG2208	phosphoserine phosphatase activity
BSK2_RS02665	COG2183	response to ionizing radiation
BSK2_RS02670	COG3091	SprT-like family
BSK2_RS02710	COG0457	Tetratricopeptide repeat
BSK2_RS02725	COG1764	response to oxidative stress
BSK2_RS02730	COG1846	Transcriptional regulator
BSK2_RS02740	COG3764	Sortase (surface protein transpeptidase)
BSK2_RS02750	COG0604	alcohol dehydrogenase
BSK2_RS02760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BSK2_RS02770	COG5444	nuclease activity
BSK2_RS02775	COG1476	TRANSCRIPTIONal
BSK2_RS02800	COG0693	protein deglycase activity
BSK2_RS02805	COG1278	Cold shock
BSK2_RS02810	COG1329	Transcriptional regulator
BSK2_RS02820	COG0697	spore germination
BSK2_RS02825	COG1917	Cupin 2, conserved barrel domain protein
BSK2_RS02825	COG2207	Transcriptional regulator
BSK2_RS02830	COG0697	spore germination
BSK2_RS02835	COG3708	Transcriptional regulator
BSK2_RS02835	COG2207	Transcriptional regulator
BSK2_RS02840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BSK2_RS02845	COG0477	Major facilitator Superfamily
BSK2_RS02855	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
BSK2_RS02875	COG1309	transcriptional regulator
BSK2_RS02880	COG0697	spore germination
BSK2_RS02885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BSK2_RS02890	COG2030	dehydratase
BSK2_RS02895	COG3545	Serine hydrolase
BSK2_RS02900	COG1733	regulation of RNA biosynthetic process
BSK2_RS02905	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BSK2_RS02910	COG1733	regulation of RNA biosynthetic process
BSK2_RS02915	COG2249	NAD(P)H dehydrogenase (quinone) activity
BSK2_RS02920	COG2814	Major facilitator Superfamily
BSK2_RS02925	COG1309	transcriptional regulator
BSK2_RS02930	COG0640	Transcriptional regulator
BSK2_RS02935	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BSK2_RS02945	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BSK2_RS02950	COG0697	spore germination
BSK2_RS02955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BSK2_RS02960	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BSK2_RS02965	COG0640	Transcriptional regulator
BSK2_RS02970	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BSK2_RS02985	COG4585	Histidine kinase
BSK2_RS02990	COG2197	response regulator
BSK2_RS02995	COG2409	Drug exporters of the RND superfamily
BSK2_RS03000	COG0596	Alpha beta hydrolase
BSK2_RS03005	COG1811	Na channel or pump
BSK2_RS03010	COG4978	Transcriptional regulator
BSK2_RS03010	COG0789	Transcriptional regulator
BSK2_RS03015	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BSK2_RS03020	COG0778	Nitroreductase
BSK2_RS03025	COG0346	lactoylglutathione lyase activity
BSK2_RS03030	COG2259	Doxx family
BSK2_RS03035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSK2_RS03050	COG2323	membrane
BSK2_RS03055	COG2323	membrane
BSK2_RS03060	COG0071	Belongs to the small heat shock protein (HSP20) family
BSK2_RS03075	COG1309	transcriptional regulator
BSK2_RS03085	COG0456	acetyltransferase
BSK2_RS03095	COG1113	amino acid transport
BSK2_RS03100	COG2318	DinB family
BSK2_RS03105	COG1846	Transcriptional regulator
BSK2_RS03110	COG1033	growth of symbiont in host cell
BSK2_RS03110	COG2409	Drug exporters of the RND superfamily
BSK2_RS03115	COG0778	Nitroreductase
BSK2_RS03120	COG1846	Transcriptional regulator
BSK2_RS03125	COG2814	Major facilitator Superfamily
BSK2_RS03130	COG0730	response to heat
BSK2_RS03135	COG1802	Transcriptional regulator
BSK2_RS03140	COG1388	LysM domain
BSK2_RS03140	COG3858	chitin binding
BSK2_RS03145	COG1819	glycosyl
BSK2_RS03155	COG1785	Belongs to the alkaline phosphatase family
BSK2_RS03160	COG5646	InterPro IPR014922
BSK2_RS03170	COG0454	-acetyltransferase
BSK2_RS03175	COG1078	dGTPase activity
BSK2_RS03180	COG1388	LysM domain
BSK2_RS03185	COG2814	Major facilitator Superfamily
BSK2_RS03190	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BSK2_RS03195	COG1447	Phosphotransferase system cellobiose-specific component IIA
BSK2_RS03200	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BSK2_RS03205	COG2723	6-phospho-beta-galactosidase activity
BSK2_RS03210	COG2188	Transcriptional regulator
BSK2_RS03215	COG1940	carbohydrate kinase activity
BSK2_RS03220	COG1482	cell wall glycoprotein biosynthetic process
BSK2_RS03225	COG4124	Belongs to the glycosyl hydrolase 26 family
BSK2_RS03270	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BSK2_RS03275	COG0802	atpase or kinase
BSK2_RS03280	COG1214	PFAM Peptidase M22, glycoprotease
BSK2_RS03285	COG0456	acetyltransferase
BSK2_RS03290	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BSK2_RS03295	COG0488	(ABC) transporter
BSK2_RS03300	COG0315	cyclic pyranopterin monophosphate synthase activity
BSK2_RS03305	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BSK2_RS03310	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BSK2_RS03315	COG0805	protein transport
BSK2_RS03325	COG1266	CAAX protease self-immunity
BSK2_RS03335	COG0459	protein refolding
BSK2_RS03345	COG1073	alpha beta
BSK2_RS03350	COG0457	Tetratricopeptide repeat
BSK2_RS03355	COG1063	alcohol dehydrogenase
BSK2_RS03360	COG2211	Major facilitator Superfamily
BSK2_RS03365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BSK2_RS03370	COG1842	Phage shock protein A
BSK2_RS03375	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BSK2_RS03380	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BSK2_RS03385	COG4260	virion core protein, lumpy skin disease virus
BSK2_RS03395	COG2814	Major facilitator Superfamily
BSK2_RS03400	COG1063	alcohol dehydrogenase
BSK2_RS03405	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BSK2_RS03410	COG0823	Involved in the tonB-independent uptake of proteins
BSK2_RS03425	COG2267	carboxylic ester hydrolase activity
BSK2_RS03435	COG2132	Multicopper oxidase
BSK2_RS03440	COG1113	amino acid transport
BSK2_RS03450	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BSK2_RS03455	COG0714	Associated with various cellular activities
BSK2_RS03460	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BSK2_RS03465	COG1305	Transglutaminase-like
BSK2_RS03470	COG0519	Catalyzes the synthesis of GMP from XMP
BSK2_RS03470	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BSK2_RS03485	COG2252	PERMEase
BSK2_RS03490	COG3064	Membrane
BSK2_RS03500	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BSK2_RS03510	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BSK2_RS03515	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BSK2_RS03520	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BSK2_RS03525	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BSK2_RS03530	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BSK2_RS03535	COG0047	phosphoribosylformylglycinamidine synthase activity
BSK2_RS03540	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BSK2_RS03545	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BSK2_RS03550	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BSK2_RS03555	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BSK2_RS03560	COG0138	bifunctional purine biosynthesis protein purh
BSK2_RS03565	COG0151	Belongs to the GarS family
BSK2_RS03570	COG1522	sequence-specific DNA binding
BSK2_RS03585	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BSK2_RS03590	COG1470	cell adhesion involved in biofilm formation
BSK2_RS03595	COG4496	protein, YerC YecD
BSK2_RS03600	COG0069	glutamate synthase activity
BSK2_RS03605	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
BSK2_RS03610	COG0210	DNA helicase
BSK2_RS03615	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BSK2_RS03620	COG4851	CamS sex pheromone cAM373 precursor
BSK2_RS03625	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BSK2_RS03630	COG1285	pathogenesis
BSK2_RS03635	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BSK2_RS03640	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BSK2_RS03645	COG0154	amidase activity
BSK2_RS03650	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BSK2_RS03655	COG1309	transcriptional regulator
BSK2_RS03660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BSK2_RS03665	COG1597	lipid kinase activity
BSK2_RS03670	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BSK2_RS03725	COG5444	nuclease activity
BSK2_RS03735	COG3586	endonuclease activity
BSK2_RS03745	COG0457	Tetratricopeptide repeat
BSK2_RS03755	COG0217	transcriptional regulatory protein
BSK2_RS03765	COG1309	transcriptional regulator
BSK2_RS03770	COG3631	Ketosteroid isomerase-related protein
BSK2_RS03790	COG3546	catalase activity
BSK2_RS03795	COG0454	-acetyltransferase
BSK2_RS03805	COG5578	integral membrane protein
BSK2_RS03810	COG2972	Histidine kinase
BSK2_RS03815	COG4753	response regulator
BSK2_RS03815	COG2207	Transcriptional regulator
BSK2_RS03820	COG1653	transport
BSK2_RS03825	COG1175	transmembrane transport
BSK2_RS03830	COG0395	ABC-type sugar transport system, permease component
BSK2_RS03835	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BSK2_RS03840	COG2207	Transcriptional regulator
BSK2_RS03845	COG2755	lipolytic protein G-D-S-L family
BSK2_RS03855	COG5578	integral membrane protein
BSK2_RS03860	COG3401	FG-GAP repeat protein
BSK2_RS03865	COG3401	FG-GAP repeat protein
BSK2_RS03870	COG2755	lipolytic protein G-D-S-L family
BSK2_RS03875	COG1874	Beta-galactosidase
BSK2_RS03885	COG1653	transport
BSK2_RS03890	COG4209	transmembrane transport
BSK2_RS03895	COG0395	ABC-type sugar transport system, permease component
BSK2_RS03900	COG1486	melibiose metabolic process
BSK2_RS03905	COG2323	membrane
BSK2_RS03910	COG2329	Antibiotic biosynthesis monooxygenase
BSK2_RS03915	COG0346	lactoylglutathione lyase activity
BSK2_RS03930	COG5583	Uncharacterized small protein (DUF2292)
BSK2_RS03935	COG0670	Belongs to the BI1 family
BSK2_RS03940	COG0697	spore germination
BSK2_RS03945	COG1846	Transcriptional regulator
BSK2_RS03950	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BSK2_RS03960	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BSK2_RS03960	COG2124	cytochrome p450
BSK2_RS03970	COG1368	sulfuric ester hydrolase activity
BSK2_RS03975	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BSK2_RS03980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BSK2_RS03985	COG1442	glycosyl transferase family 8
BSK2_RS03990	COG1216	Glycosyl transferase, family 2
BSK2_RS03995	COG1442	glycosyl transferase family 8
BSK2_RS04000	COG2223	nitrite transmembrane transporter activity
BSK2_RS04005	COG1011	Hydrolase
BSK2_RS04010	COG0531	amino acid
BSK2_RS04015	COG1012	belongs to the aldehyde dehydrogenase family
BSK2_RS04020	COG0840	transmembrane signaling receptor activity
BSK2_RS04025	COG0488	(ABC) transporter
BSK2_RS04035	COG0789	Transcriptional regulator
BSK2_RS04040	COG2814	Major facilitator Superfamily
BSK2_RS04055	COG0488	(ABC) transporter
BSK2_RS04060	COG0513	Belongs to the DEAD box helicase family
BSK2_RS04065	COG0456	acetyltransferase
BSK2_RS04070	COG2130	NADP-dependent
BSK2_RS04075	COG1120	ATPase activity
BSK2_RS04080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BSK2_RS04085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BSK2_RS04090	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BSK2_RS04110	COG3866	Pectate lyase
BSK2_RS04115	COG0471	metal ion transport
BSK2_RS04120	COG3290	protein histidine kinase activity
BSK2_RS04125	COG4565	transcriptional regulatory protein
BSK2_RS04130	COG3181	Tripartite tricarboxylate transporter family receptor
BSK2_RS04135	COG2851	Citrate transporter
BSK2_RS04140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSK2_RS04145	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BSK2_RS04150	COG1254	Belongs to the acylphosphatase family
BSK2_RS04155	COG2258	MOSC domain
BSK2_RS04175	COG0024	Methionine aminopeptidase
BSK2_RS04180	COG1263	PTS System
BSK2_RS04180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BSK2_RS04185	COG1368	sulfuric ester hydrolase activity
BSK2_RS04200	COG1115	amino acid carrier protein
BSK2_RS04205	COG0531	amino acid
BSK2_RS04220	COG0697	spore germination
BSK2_RS04225	COG1263	PTS System
BSK2_RS04225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BSK2_RS04230	COG0366	Alpha amylase catalytic
BSK2_RS04235	COG2188	Transcriptional regulator
BSK2_RS04240	COG0778	Nitroreductase
BSK2_RS04245	COG0737	Belongs to the 5'-nucleotidase family
BSK2_RS04250	COG0693	protein deglycase activity
BSK2_RS04255	COG2814	Major facilitator Superfamily
BSK2_RS04260	COG4840	Belongs to the UPF0435 family
BSK2_RS04265	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BSK2_RS04270	COG4980	gas vesicle protein
BSK2_RS04275	COG1295	ribonuclease BN
BSK2_RS04280	COG0477	Major facilitator Superfamily
BSK2_RS04285	COG0387	Pfam Sodium calcium exchanger
BSK2_RS04295	COG0668	transmembrane transport
BSK2_RS04300	COG0535	radical SAM domain protein
BSK2_RS04310	COG0726	polysaccharide deacetylase
BSK2_RS04315	COG2084	Dehydrogenase
BSK2_RS04320	COG0598	Magnesium transport protein CorA
BSK2_RS04325	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BSK2_RS04330	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BSK2_RS04340	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BSK2_RS04345	COG4637	Psort location Cytoplasmic, score
BSK2_RS04355	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BSK2_RS04360	COG0022	dehydrogenase e1 component
BSK2_RS04365	COG0508	dehydrogenase complex catalyzes the overall conversion of
BSK2_RS04370	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BSK2_RS04375	COG3284	Transcriptional regulator
BSK2_RS04385	COG1742	UPF0060 membrane protein
BSK2_RS04405	COG4842	Belongs to the WXG100 family
BSK2_RS04410	COG1486	melibiose metabolic process
BSK2_RS04415	COG1737	Transcriptional regulator
BSK2_RS04420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BSK2_RS04420	COG1263	PTS System
BSK2_RS04425	COG1132	(ABC) transporter
BSK2_RS04430	COG1132	(ABC) transporter
BSK2_RS04435	COG2259	Doxx family
BSK2_RS04440	COG2514	catechol 2,3-dioxygenase activity
BSK2_RS04445	COG4585	Histidine kinase
BSK2_RS04450	COG2197	response regulator
BSK2_RS04455	COG1131	(ABC) transporter
BSK2_RS04460	COG1511	domain protein
BSK2_RS04460	COG0842	Transport permease protein
BSK2_RS04465	COG0842	Transport permease protein
BSK2_RS04470	COG1695	Transcriptional regulator
BSK2_RS04475	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BSK2_RS04480	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
BSK2_RS04485	COG1309	transcriptional regulator
BSK2_RS04490	COG2814	Major facilitator Superfamily
BSK2_RS04495	COG2318	DinB family
BSK2_RS04500	COG2814	Major facilitator Superfamily
BSK2_RS04505	COG1846	Transcriptional regulator
BSK2_RS04510	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BSK2_RS04510	COG0392	lysyltransferase activity
BSK2_RS04515	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BSK2_RS04520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BSK2_RS04525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BSK2_RS04530	COG0384	phenazine biosynthesis protein PhzF
BSK2_RS04535	COG0778	Nitroreductase
BSK2_RS04550	COG1090	epimerase
BSK2_RS04555	COG2137	regulation of response to DNA damage stimulus
BSK2_RS04565	COG2814	Major facilitator Superfamily
BSK2_RS04580	COG3103	Sh3 type 3 domain protein
BSK2_RS04585	COG5658	integral membrane protein
BSK2_RS04590	COG0596	Alpha beta hydrolase
BSK2_RS04595	COG0463	Glycosyl transferase, family 2
BSK2_RS04600	COG4485	Bacterial membrane protein, YfhO
BSK2_RS04605	COG1988	membrane-bound metal-dependent
BSK2_RS04610	COG1194	a g-specific adenine glycosylase
BSK2_RS04620	COG1028	Short-chain dehydrogenase reductase Sdr
BSK2_RS04635	COG3557	Belongs to the UPF0374 family
BSK2_RS04640	COG1132	(ABC) transporter
BSK2_RS04645	COG4129	membrane
BSK2_RS04650	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BSK2_RS04655	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BSK2_RS04660	COG0735	belongs to the Fur family
BSK2_RS04770	COG4326	sporulation control protein
BSK2_RS04780	COG5577	PFAM Coat F domain
BSK2_RS04785	COG3340	Belongs to the peptidase S51 family
BSK2_RS04790	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BSK2_RS04795	COG0277	FAD linked oxidase domain protein
BSK2_RS04805	COG0753	catalase activity
BSK2_RS04810	COG1116	anion transmembrane transporter activity
BSK2_RS04815	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BSK2_RS04820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BSK2_RS04825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BSK2_RS04835	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BSK2_RS04845	COG1476	TRANSCRIPTIONal
BSK2_RS04855	COG3382	B3 4 domain protein
BSK2_RS04860	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BSK2_RS04870	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BSK2_RS04875	COG0789	Transcriptional regulator
BSK2_RS04880	COG1664	Polymer-forming cytoskeletal
BSK2_RS04885	COG1664	Polymer-forming cytoskeletal
BSK2_RS04890	COG2766	serine protein kinase
BSK2_RS04895	COG2718	Belongs to the UPF0229 family
BSK2_RS04900	COG1846	Transcriptional regulator
BSK2_RS04905	COG1566	PFAM secretion protein HlyD family protein
BSK2_RS04910	COG2814	Major facilitator Superfamily
BSK2_RS04915	COG0655	NAD(P)H dehydrogenase (quinone) activity
BSK2_RS04935	COG1725	Transcriptional regulator
BSK2_RS04940	COG1131	(ABC) transporter
BSK2_RS04945	COG1131	(ABC) transporter
BSK2_RS04950	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BSK2_RS04955	COG1278	Cold shock
BSK2_RS04965	COG1464	Belongs to the NlpA lipoprotein family
BSK2_RS04970	COG3706	GGDEF domain
BSK2_RS04975	COG1823	symporter activity
BSK2_RS04995	COG5577	PFAM Coat F domain
BSK2_RS05000	COG0737	Belongs to the 5'-nucleotidase family
BSK2_RS05000	COG1525	nuclease
BSK2_RS05000	COG4085	toxin activity
BSK2_RS05005	COG3764	Sortase (surface protein transpeptidase)
BSK2_RS05010	COG0564	pseudouridine synthase activity
BSK2_RS05020	COG0517	IMP dehydrogenase activity
BSK2_RS05025	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BSK2_RS05030	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BSK2_RS05030	COG3153	acetyltransferase
BSK2_RS05035	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BSK2_RS05040	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BSK2_RS05045	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BSK2_RS05050	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BSK2_RS05055	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BSK2_RS05060	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BSK2_RS05065	COG2203	Gaf domain
BSK2_RS05065	COG4585	Histidine kinase
BSK2_RS05070	COG2197	response regulator
BSK2_RS05075	COG0431	NADPH-dependent FMN reductase
BSK2_RS05090	COG1388	LysM domain
BSK2_RS05090	COG0791	NLP P60 protein
BSK2_RS05095	COG1959	2 iron, 2 sulfur cluster binding
BSK2_RS05100	COG0668	transmembrane transport
BSK2_RS05105	COG2719	SpoVR family
BSK2_RS05110	COG1785	Belongs to the alkaline phosphatase family
BSK2_RS05115	COG0791	NLP P60 protein
BSK2_RS05115	COG1388	LysM domain
BSK2_RS05120	COG0583	DNA-binding transcription factor activity
BSK2_RS05125	COG0372	Belongs to the citrate synthase family
BSK2_RS05130	COG1028	Short-chain dehydrogenase reductase Sdr
BSK2_RS05135	COG0531	amino acid
BSK2_RS05140	COG0733	neurotransmitter:sodium symporter activity
BSK2_RS05145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BSK2_RS05150	COG0456	acetyltransferase
BSK2_RS05165	COG1595	DNA-templated transcription, initiation
BSK2_RS05170	COG0667	Aldo Keto reductase
BSK2_RS05175	COG0204	Acyl-transferase
BSK2_RS05180	COG1253	flavin adenine dinucleotide binding
BSK2_RS05185	COG0789	Transcriptional regulator
BSK2_RS05190	COG0436	Aminotransferase
BSK2_RS05195	COG1253	flavin adenine dinucleotide binding
BSK2_RS05200	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BSK2_RS05205	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BSK2_RS05210	COG0584	glycerophosphoryl diester phosphodiesterase
BSK2_RS05220	COG0668	transmembrane transport
BSK2_RS05225	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BSK2_RS05230	COG0726	polysaccharide deacetylase
BSK2_RS05235	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BSK2_RS05240	COG1757	Na H antiporter
BSK2_RS05245	COG0589	response to stress
BSK2_RS05255	COG1132	(ABC) transporter
BSK2_RS05260	COG1132	(ABC) transporter
BSK2_RS05265	COG0702	epimerase
BSK2_RS05285	COG0189	ligase activity
BSK2_RS05290	COG0189	ligase activity
BSK2_RS05295	COG4399	Belongs to the UPF0754 family
BSK2_RS05300	COG3679	Belongs to the UPF0342 family
BSK2_RS05305	COG4335	DNA alkylation repair
BSK2_RS05310	COG0561	phosphatase activity
BSK2_RS05315	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BSK2_RS05320	COG0475	glutathione-regulated potassium exporter activity
BSK2_RS05325	COG0490	domain, Protein
BSK2_RS05335	COG1024	Enoyl-CoA hydratase
BSK2_RS05345	COG4152	abc transporter atp-binding protein
BSK2_RS05350	COG1668	transmembrane transport
BSK2_RS05355	COG0420	3'-5' exonuclease activity
BSK2_RS05360	COG4717	serine-type aminopeptidase activity
BSK2_RS05365	COG3481	metal-dependent phosphohydrolase, HD sub domain
BSK2_RS05375	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BSK2_RS05405	COG1846	Transcriptional regulator
BSK2_RS05410	COG4980	gas vesicle protein
BSK2_RS05425	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BSK2_RS05430	COG0537	adenosine 5'-monophosphoramidase activity
BSK2_RS05435	COG1131	(ABC) transporter
BSK2_RS05440	COG4473	ABC transporter
BSK2_RS05450	COG1473	amidohydrolase
BSK2_RS05455	COG3069	C4-dicarboxylate transmembrane transporter activity
BSK2_RS05465	COG2329	Antibiotic biosynthesis monooxygenase
BSK2_RS05470	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BSK2_RS05475	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BSK2_RS05480	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BSK2_RS05485	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BSK2_RS05490	COG1309	transcriptional regulator
BSK2_RS05495	COG1511	domain protein
BSK2_RS05500	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BSK2_RS05505	COG4377	Putative membrane peptidase family (DUF2324)
BSK2_RS05515	COG1363	Peptidase, m42
BSK2_RS05520	COG4405	Protein conserved in bacteria
BSK2_RS05525	COG1301	dicarboxylic acid transport
BSK2_RS05540	COG0095	Lipoate-protein ligase
BSK2_RS05545	COG0702	epimerase
BSK2_RS05550	COG0318	PFAM AMP-dependent synthetase and ligase
BSK2_RS05560	COG0501	Belongs to the peptidase M48B family
BSK2_RS05570	COG0456	acetyltransferase
BSK2_RS05575	COG0604	alcohol dehydrogenase
BSK2_RS05580	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BSK2_RS05585	COG0406	alpha-ribazole phosphatase activity
BSK2_RS05590	COG0183	Belongs to the thiolase family
BSK2_RS05595	COG0318	PFAM AMP-dependent synthetase and ligase
BSK2_RS05600	COG1268	BioY protein
BSK2_RS05605	COG0840	transmembrane signaling receptor activity
BSK2_RS05610	COG0723	plastoquinol--plastocyanin reductase activity
BSK2_RS05610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSK2_RS05615	COG1028	Short-chain dehydrogenase reductase Sdr
BSK2_RS05625	COG4903	ComK protein
BSK2_RS05630	COG1028	Short-chain dehydrogenase reductase Sdr
BSK2_RS05640	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BSK2_RS05655	COG0398	Pfam SNARE associated Golgi protein
BSK2_RS05660	COG0681	Belongs to the peptidase S26 family
BSK2_RS05665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BSK2_RS05670	COG1846	Transcriptional regulator
BSK2_RS05675	COG0738	Major facilitator superfamily
BSK2_RS05680	COG0673	inositol 2-dehydrogenase activity
BSK2_RS05685	COG0561	phosphatase activity
BSK2_RS05690	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BSK2_RS05695	COG1609	Transcriptional regulator
BSK2_RS05700	COG3180	Ammonia monooxygenase
BSK2_RS05705	COG2814	Major facilitator Superfamily
BSK2_RS05705	COG0477	Major facilitator Superfamily
BSK2_RS05710	COG4533	DNA binding
BSK2_RS05720	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BSK2_RS05725	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BSK2_RS05730	COG1074	ATP-dependent DNA helicase activity
BSK2_RS05735	COG0420	3'-5' exonuclease activity
BSK2_RS05740	COG0419	ATPase involved in DNA repair
BSK2_RS05745	COG1403	HNH endonuclease
BSK2_RS05785	COG5337	Spore coat protein CotH
BSK2_RS05790	COG0179	Fumarylacetoacetate (FAA) hydrolase
BSK2_RS05800	COG1404	Belongs to the peptidase S8 family
BSK2_RS05810	COG0367	asparagine synthase
BSK2_RS05815	COG2318	DinB family
BSK2_RS05820	COG1562	ergosterol biosynthetic process
BSK2_RS05825	COG0534	Mate efflux family protein
BSK2_RS05830	COG1917	Cupin 2, conserved barrel domain protein
BSK2_RS05830	COG2207	Transcriptional regulator
BSK2_RS05835	COG1609	Transcriptional regulator
BSK2_RS05840	COG0673	inositol 2-dehydrogenase activity
BSK2_RS05845	COG2318	DinB family
BSK2_RS05850	COG1279	arginine transmembrane transporter activity
BSK2_RS05855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BSK2_RS05860	COG1357	PFAM Pentapeptide repeats (8 copies)
BSK2_RS05865	COG2267	carboxylic ester hydrolase activity
BSK2_RS05870	COG0529	Catalyzes the synthesis of activated sulfate
BSK2_RS05875	COG2046	Belongs to the sulfate adenylyltransferase family
BSK2_RS05880	COG0175	sulfate reduction
BSK2_RS05885	COG2045	Belongs to the ComB family
BSK2_RS05890	COG1809	phosphosulfolactate synthase activity
BSK2_RS05895	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BSK2_RS05900	COG4948	Mandelate Racemase Muconate Lactonizing
BSK2_RS05905	COG2814	Major facilitator Superfamily
BSK2_RS05910	COG0454	-acetyltransferase
BSK2_RS05915	COG2153	protein acetylation
BSK2_RS05920	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BSK2_RS05920	COG0646	methionine synthase
BSK2_RS05925	COG1666	GTP binding
BSK2_RS05930	COG2996	Protein conserved in bacteria
BSK2_RS05950	COG1695	Transcriptional regulator
BSK2_RS05965	COG3227	Zinc metalloprotease (Elastase)
BSK2_RS05970	COG1307	EDD domain protein, DegV family
BSK2_RS05975	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BSK2_RS05990	COG0561	phosphatase activity
BSK2_RS05995	COG1073	alpha beta
BSK2_RS06000	COG2151	metal-sulfur cluster biosynthetic enzyme
BSK2_RS06010	COG0277	FAD linked oxidase domain protein
BSK2_RS06015	COG2271	Major facilitator Superfamily
BSK2_RS06020	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BSK2_RS06025	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BSK2_RS06035	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BSK2_RS06040	COG0505	Belongs to the CarA family
BSK2_RS06045	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BSK2_RS06050	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BSK2_RS06065	COG2267	carboxylic ester hydrolase activity
BSK2_RS06075	COG1744	ABC transporter substrate-binding protein PnrA-like
BSK2_RS06090	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BSK2_RS06095	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BSK2_RS06100	COG5504	Zn-dependent protease
BSK2_RS06105	COG0444	Belongs to the ABC transporter superfamily
BSK2_RS06110	COG4608	Belongs to the ABC transporter superfamily
BSK2_RS06120	COG0601	transmembrane transport
BSK2_RS06125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BSK2_RS06135	COG0180	Tryptophanyl-tRNA synthetase
BSK2_RS06140	COG4166	transmembrane transport
BSK2_RS06145	COG0601	transmembrane transport
BSK2_RS06150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BSK2_RS06155	COG0444	Belongs to the ABC transporter superfamily
BSK2_RS06160	COG4608	Belongs to the ABC transporter superfamily
BSK2_RS06165	COG2814	Major facilitator Superfamily
BSK2_RS06170	COG0456	acetyltransferase
BSK2_RS06175	COG1393	Belongs to the ArsC family
BSK2_RS06180	COG0861	Integral membrane protein TerC family
BSK2_RS06185	COG4862	establishment of competence for transformation
BSK2_RS06190	COG4469	Competence protein
BSK2_RS06195	COG1164	Oligoendopeptidase f
BSK2_RS06210	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BSK2_RS06215	COG2346	COG2346, Truncated hemoglobins
BSK2_RS06220	COG0741	lytic transglycosylase activity
BSK2_RS06225	COG4116	CYTH
BSK2_RS06235	COG2357	RelA SpoT domain protein
BSK2_RS06240	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BSK2_RS06245	COG0564	pseudouridine synthase activity
BSK2_RS06250	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BSK2_RS06255	COG0569	domain protein
BSK2_RS06255	COG0475	glutathione-regulated potassium exporter activity
BSK2_RS06260	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BSK2_RS06265	COG0352	thiamine-phosphate diphosphorylase activity
BSK2_RS06270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSK2_RS06275	COG2104	thiamine diphosphate biosynthetic process
BSK2_RS06280	COG2022	thiamine diphosphate biosynthetic process
BSK2_RS06285	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BSK2_RS06290	COG0351	phosphomethylpyrimidine kinase
BSK2_RS06295	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BSK2_RS06350	COG0210	DNA helicase
BSK2_RS06360	COG2153	protein acetylation
BSK2_RS06365	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BSK2_RS06370	COG2382	esterase
BSK2_RS06375	COG0626	cystathionine gamma-synthase activity
BSK2_RS06380	COG0626	cystathionine gamma-synthase activity
BSK2_RS06385	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BSK2_RS06390	COG5505	Protein of unknown function (DUF819)
BSK2_RS06410	COG5444	nuclease activity
BSK2_RS06475	COG5484	DNA packaging
BSK2_RS06480	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BSK2_RS06485	COG1028	Short-chain dehydrogenase reductase Sdr
BSK2_RS06495	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BSK2_RS06495	COG3711	transcriptional antiterminator
BSK2_RS06505	COG1482	cell wall glycoprotein biosynthetic process
BSK2_RS06515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BSK2_RS06525	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BSK2_RS06545	COG0109	protoheme IX farnesyltransferase activity
BSK2_RS06555	COG0726	polysaccharide deacetylase
BSK2_RS06570	COG5504	Zn-dependent protease
BSK2_RS06575	COG2205	protein histidine kinase activity
BSK2_RS06585	COG3383	formate dehydrogenase (NAD+) activity
BSK2_RS06590	COG2427	Protein of unknown function (DUF1641)
BSK2_RS06600	COG1051	belongs to the nudix hydrolase family
BSK2_RS06610	COG2124	cytochrome p450
BSK2_RS06615	COG1819	glycosyl
BSK2_RS06625	COG1587	Uroporphyrinogen-III synthase
BSK2_RS06630	COG0390	transport system, permease component
BSK2_RS06635	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BSK2_RS06640	COG0697	spore germination
BSK2_RS06645	COG4297	protein containing double-stranded beta helix domain
BSK2_RS06655	COG1252	NADH dehydrogenase
BSK2_RS06660	COG1904	glucuronate isomerase
BSK2_RS06665	COG2211	Major facilitator Superfamily
BSK2_RS06670	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BSK2_RS06675	COG1063	alcohol dehydrogenase
BSK2_RS06680	COG1312	Catalyzes the dehydration of D-mannonate
BSK2_RS06685	COG1028	Short-chain dehydrogenase reductase Sdr
BSK2_RS06690	COG2271	Major facilitator Superfamily
BSK2_RS06695	COG1609	Transcriptional regulator
BSK2_RS06700	COG0246	Mannitol dehydrogenase
BSK2_RS06705	COG2721	sulfolactate sulfo-lyase activity
BSK2_RS06710	COG0730	response to heat
BSK2_RS06715	COG2318	DinB family
BSK2_RS06720	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BSK2_RS06725	COG0457	Tetratricopeptide repeat
BSK2_RS06735	COG2350	Protein conserved in bacteria
BSK2_RS06740	COG3409	Peptidoglycan-binding domain 1 protein
BSK2_RS06740	COG5632	N-Acetylmuramoyl-L-alanine amidase
BSK2_RS06740	COG1388	LysM domain
BSK2_RS06750	COG4195	phage-related replication protein
BSK2_RS06755	COG3546	catalase activity
BSK2_RS06760	COG2856	Zn peptidase
BSK2_RS06765	COG1396	sequence-specific DNA binding
BSK2_RS06775	COG1522	sequence-specific DNA binding
BSK2_RS06780	COG1484	DNA-dependent DNA replication
BSK2_RS06800	COG1595	DNA-templated transcription, initiation
BSK2_RS06805	COG3728	DNA packaging
BSK2_RS06805	COG5484	DNA packaging
BSK2_RS06810	COG1783	phage Terminase large subunit
BSK2_RS06815	COG5518	Phage portal protein
BSK2_RS06820	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BSK2_RS06825	COG4653	Phage capsid family
BSK2_RS06875	COG5412	phage tail tape measure protein
BSK2_RS06875	COG3953	SLT domain
BSK2_RS06880	COG1652	LysM domain
BSK2_RS06885	COG4193	domain, Protein
BSK2_RS06895	COG3628	GPW Gp25 family protein
BSK2_RS06900	COG3299	homolog of phage Mu protein gp47
BSK2_RS06905	COG3778	Protein conserved in bacteria
BSK2_RS06945	COG3409	Peptidoglycan-binding domain 1 protein
BSK2_RS06945	COG5632	N-Acetylmuramoyl-L-alanine amidase
BSK2_RS06960	COG0306	phosphate transporter
BSK2_RS06965	COG1392	Phosphate transport regulator
BSK2_RS06970	COG0531	amino acid
BSK2_RS06975	COG0346	lactoylglutathione lyase activity
BSK2_RS06980	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BSK2_RS06985	COG0463	Glycosyl transferase, family 2
BSK2_RS06995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BSK2_RS07000	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BSK2_RS07005	COG2362	D-Aminopeptidase
BSK2_RS07010	COG0601	transmembrane transport
BSK2_RS07015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BSK2_RS07020	COG0444	Belongs to the ABC transporter superfamily
BSK2_RS07025	COG4166	transmembrane transport
BSK2_RS07030	COG1619	proteins homologs of microcin C7 resistance protein MccF
BSK2_RS07035	COG4948	Mandelate Racemase Muconate Lactonizing
BSK2_RS07040	COG0791	NLP P60 protein
BSK2_RS07045	COG4608	Belongs to the ABC transporter superfamily
BSK2_RS07050	COG2706	6-phosphogluconolactonase activity
BSK2_RS07055	COG1834	amidinotransferase
BSK2_RS07060	COG1607	acyl-coa hydrolase
BSK2_RS07065	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BSK2_RS07065	COG1017	nitric oxide dioxygenase activity
BSK2_RS07075	COG2323	membrane
BSK2_RS07080	COG2318	DinB family
BSK2_RS07085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BSK2_RS07090	COG2076	Multidrug Resistance protein
BSK2_RS07095	COG2076	Multidrug Resistance protein
BSK2_RS07100	COG0788	formyltetrahydrofolate deformylase activity
BSK2_RS07105	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BSK2_RS07110	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BSK2_RS07115	COG1764	response to oxidative stress
BSK2_RS07120	COG1846	Transcriptional regulator
BSK2_RS07125	COG1764	response to oxidative stress
BSK2_RS07135	COG0590	tRNA wobble adenosine to inosine editing
BSK2_RS07145	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BSK2_RS07150	COG1404	Belongs to the peptidase S8 family
BSK2_RS07155	COG1366	Belongs to the anti-sigma-factor antagonist family
BSK2_RS07160	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BSK2_RS07165	COG1122	ATPase activity
BSK2_RS07170	COG4721	ABC-type cobalt transport system, permease component
BSK2_RS07180	COG0745	RESPONSE REGULATOR receiver
BSK2_RS07185	COG5002	protein histidine kinase activity
BSK2_RS07185	COG3850	Histidine kinase
BSK2_RS07190	COG3212	peptidase
BSK2_RS07195	COG3212	peptidase
BSK2_RS07205	COG2239	Acts as a magnesium transporter
BSK2_RS07210	COG0789	Transcriptional regulator
BSK2_RS07225	COG1846	Transcriptional regulator
BSK2_RS07230	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BSK2_RS07235	COG0726	polysaccharide deacetylase
BSK2_RS07240	COG1408	metallophosphoesterase
BSK2_RS07250	COG0463	Glycosyl transferase, family 2
BSK2_RS07255	COG1793	dna ligase
BSK2_RS07255	COG3285	dna ligase
BSK2_RS07260	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BSK2_RS07265	COG5001	Diguanylate cyclase
BSK2_RS07265	COG3300	MHYT domain
BSK2_RS07270	COG0586	Pfam SNARE associated Golgi protein
BSK2_RS07275	COG0861	Integral membrane protein TerC family
BSK2_RS07280	COG1191	sigma factor activity
BSK2_RS07300	COG0501	Belongs to the peptidase M48B family
BSK2_RS07305	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BSK2_RS07320	COG3594	Acyltransferase
BSK2_RS07325	COG5002	protein histidine kinase activity
BSK2_RS07330	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BSK2_RS07335	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BSK2_RS07340	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BSK2_RS07345	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BSK2_RS07350	COG0436	Aminotransferase
BSK2_RS07355	COG1850	ribulose-bisphosphate carboxylase activity
BSK2_RS07360	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
BSK2_RS07365	COG0235	Class ii aldolase
BSK2_RS07370	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BSK2_RS07375	COG3339	Conserved Protein
BSK2_RS07390	COG3852	Histidine kinase
BSK2_RS07395	COG1846	Transcriptional regulator
BSK2_RS07400	COG1360	Flagellar Motor Protein
BSK2_RS07405	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BSK2_RS07410	COG0542	response to heat
BSK2_RS07415	COG3949	Membrane
BSK2_RS07420	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BSK2_RS07425	COG0720	synthase
BSK2_RS07430	COG0602	queuosine metabolic process
BSK2_RS07435	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BSK2_RS07440	COG1733	regulation of RNA biosynthetic process
BSK2_RS07445	COG1028	Short-chain dehydrogenase reductase Sdr
BSK2_RS07450	COG1388	LysM domain
BSK2_RS07450	COG4641	Protein conserved in bacteria
BSK2_RS07455	COG1388	LysM domain
BSK2_RS07460	COG3858	chitin binding
BSK2_RS07470	COG4873	Protein conserved in bacteria
BSK2_RS07480	COG3773	Cell wall hydrolase
BSK2_RS07485	COG2244	polysaccharide biosynthetic process
BSK2_RS07490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSK2_RS07495	COG2217	Heavy metal translocating P-type atpase
BSK2_RS07505	COG0006	proline dipeptidase activity
BSK2_RS07510	COG1609	Transcriptional regulator
BSK2_RS07515	COG3711	transcriptional antiterminator
BSK2_RS07520	COG1263	PTS System
BSK2_RS07520	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BSK2_RS07520	COG2190	(PTS) system
BSK2_RS07525	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BSK2_RS07530	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BSK2_RS07540	COG1533	DNA photolyase activity
BSK2_RS07545	COG0456	acetyltransferase
BSK2_RS07550	COG0840	transmembrane signaling receptor activity
BSK2_RS07555	COG2084	Dehydrogenase
BSK2_RS07560	COG2340	Cysteine-rich secretory protein family
BSK2_RS07565	COG0768	penicillin binding
BSK2_RS07570	COG4191	Histidine kinase
BSK2_RS07575	COG0436	Aminotransferase
BSK2_RS07585	COG0835	chemotaxis
BSK2_RS07585	COG0784	Response regulator, receiver
BSK2_RS07595	COG2814	Major facilitator Superfamily
BSK2_RS07600	COG1376	ErfK ybiS ycfS ynhG family protein
BSK2_RS07605	COG1408	metallophosphoesterase
BSK2_RS07610	COG1028	Short-chain dehydrogenase reductase Sdr
BSK2_RS07615	COG2200	EAL domain
BSK2_RS07620	COG4703	Protein of unknown function (DUF1797)
BSK2_RS07625	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BSK2_RS07635	COG0517	IMP dehydrogenase activity
BSK2_RS07640	COG0583	DNA-binding transcription factor activity
BSK2_RS07645	COG0716	FMN binding
BSK2_RS07655	COG0716	FMN binding
BSK2_RS07660	COG2171	N-acyltransferase activity
BSK2_RS07665	COG1473	amidohydrolase
BSK2_RS07675	COG0668	transmembrane transport
BSK2_RS07680	COG0450	alkyl hydroperoxide reductase
BSK2_RS07685	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSK2_RS07700	COG0746	molybdenum cofactor guanylyltransferase activity
BSK2_RS07705	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BSK2_RS07710	COG0303	'Molybdopterin
BSK2_RS07715	COG1763	Mo-molybdopterin cofactor biosynthetic process
BSK2_RS07720	COG0314	molybdopterin synthase activity
BSK2_RS07725	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BSK2_RS07730	COG1132	(ABC) transporter
BSK2_RS07735	COG1132	(ABC) transporter
BSK2_RS07745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSK2_RS07750	COG1136	(ABC) transporter
BSK2_RS07755	COG0577	efflux transmembrane transporter activity
BSK2_RS07760	COG1349	DNA-binding transcription factor activity
BSK2_RS07765	COG1105	Belongs to the carbohydrate kinase PfkB family
BSK2_RS07770	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BSK2_RS07770	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BSK2_RS07770	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BSK2_RS07775	COG0681	Belongs to the peptidase S26 family
BSK2_RS07785	COG0488	(ABC) transporter
BSK2_RS07790	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BSK2_RS07795	COG2309	aminopeptidase activity
BSK2_RS07805	COG1077	Cell shape determining protein MreB Mrl
BSK2_RS07810	COG2002	toxin-antitoxin pair type II binding
BSK2_RS07815	COG3852	Histidine kinase
BSK2_RS07820	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BSK2_RS07820	COG2105	PFAM AIG2 family protein
BSK2_RS07825	COG0569	domain protein
BSK2_RS07830	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BSK2_RS07835	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BSK2_RS07840	COG5503	Protein of unknown function (DUF1447)
BSK2_RS07845	COG0561	phosphatase activity
BSK2_RS07850	COG0242	peptide deformylase activity
BSK2_RS07860	COG0497	DNA recombination
BSK2_RS07865	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BSK2_RS07870	COG0022	dehydrogenase e1 component
BSK2_RS07875	COG0508	dehydrogenase complex catalyzes the overall conversion of
BSK2_RS07880	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BSK2_RS07885	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSK2_RS07895	COG1982	Orn Lys Arg decarboxylase major
BSK2_RS07900	COG4476	Belongs to the UPF0223 family
BSK2_RS07905	COG4493	Belongs to the UPF0637 family
BSK2_RS07915	COG0483	inositol monophosphate 1-phosphatase activity
BSK2_RS07925	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BSK2_RS07945	COG1595	DNA-templated transcription, initiation
BSK2_RS07965	COG1217	gtp-binding protein TYPA
BSK2_RS07975	COG4896	Protein conserved in bacteria
BSK2_RS07985	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BSK2_RS07990	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BSK2_RS07995	COG2066	Belongs to the glutaminase family
BSK2_RS08000	COG4838	Belongs to the UPF0358 family
BSK2_RS08005	COG0772	Belongs to the SEDS family
BSK2_RS08010	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BSK2_RS08015	COG1612	heme a metabolic process
BSK2_RS08020	COG0109	protoheme IX farnesyltransferase activity
BSK2_RS08025	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BSK2_RS08025	COG2010	Cytochrome c
BSK2_RS08030	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BSK2_RS08035	COG1845	cytochrome c oxidase, subunit III
BSK2_RS08040	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BSK2_RS08045	COG3336	cytochrome c oxidase
BSK2_RS08055	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BSK2_RS08060	COG2340	Cysteine-rich secretory protein family
BSK2_RS08075	COG3679	Belongs to the UPF0342 family
BSK2_RS08080	COG4471	UPF0298 protein
BSK2_RS08085	COG0742	ribosomal rna small subunit methyltransferase
BSK2_RS08090	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BSK2_RS08095	COG3314	Sporulation integral membrane protein YlbJ
BSK2_RS08100	COG1752	Esterase of the alpha-beta hydrolase superfamily
BSK2_RS08105	COG3480	Lon protease (S16) C-terminal proteolytic domain
BSK2_RS08110	COG1323	Belongs to the UPF0348 family
BSK2_RS08120	COG1399	metal-binding, possibly nucleic acid-binding protein
BSK2_RS08135	COG0454	-acetyltransferase
BSK2_RS08140	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BSK2_RS08145	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BSK2_RS08150	COG2001	Belongs to the MraZ family
BSK2_RS08155	COG0275	rRNA processing
BSK2_RS08160	COG4839	cell division protein FtsL
BSK2_RS08165	COG0768	penicillin binding
BSK2_RS08170	COG0768	penicillin binding
BSK2_RS08175	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BSK2_RS08180	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BSK2_RS08185	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BSK2_RS08190	COG0772	Belongs to the SEDS family
BSK2_RS08195	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BSK2_RS08200	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BSK2_RS08205	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BSK2_RS08210	COG3879	Bacterial protein of unknown function (DUF881)
BSK2_RS08215	COG3879	Bacterial protein of unknown function (DUF881)
BSK2_RS08220	COG3856	small basic protein
BSK2_RS08225	COG0849	cell division
BSK2_RS08230	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BSK2_RS08235	COG1404	Belongs to the peptidase S8 family
BSK2_RS08235	COG4412	M6 family metalloprotease domain protein
BSK2_RS08245	COG1191	sigma factor activity
BSK2_RS08250	COG1191	sigma factor activity
BSK2_RS08255	COG1119	ATPase activity
BSK2_RS08260	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BSK2_RS08265	COG1873	PFAM PRC-barrel domain
BSK2_RS08270	COG1496	oxidoreductase activity
BSK2_RS08275	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BSK2_RS08280	COG1799	cell septum assembly
BSK2_RS08285	COG0762	integral membrane protein
BSK2_RS08290	COG2302	S4 RNA-binding domain
BSK2_RS08295	COG3599	regulation of cell shape
BSK2_RS08300	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BSK2_RS08305	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BSK2_RS08310	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BSK2_RS08315	COG0564	pseudouridine synthase activity
BSK2_RS08320	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BSK2_RS08325	COG2233	PERMEase
BSK2_RS08330	COG0540	Belongs to the ATCase OTCase family
BSK2_RS08335	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BSK2_RS08340	COG0505	Belongs to the CarA family
BSK2_RS08345	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BSK2_RS08350	COG0543	2 iron, 2 sulfur cluster binding
BSK2_RS08355	COG0167	dihydroorotate dehydrogenase activity
BSK2_RS08360	COG0284	orotidine-5'-phosphate decarboxylase activity
BSK2_RS08365	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BSK2_RS08370	COG0175	sulfate reduction
BSK2_RS08375	COG0306	phosphate transporter
BSK2_RS08380	COG2046	Belongs to the sulfate adenylyltransferase family
BSK2_RS08385	COG0529	Catalyzes the synthesis of activated sulfate
BSK2_RS08390	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BSK2_RS08395	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
BSK2_RS08400	COG1648	precorrin-2 dehydrogenase activity
BSK2_RS08405	COG1293	RNA-binding protein homologous to eukaryotic snRNP
BSK2_RS08410	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BSK2_RS08415	COG1561	YicC-like family, N-terminal region
BSK2_RS08425	COG0194	GDP metabolic process
BSK2_RS08430	COG1758	RNA polymerase activity
BSK2_RS08435	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BSK2_RS08440	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BSK2_RS08445	COG0242	peptide deformylase activity
BSK2_RS08450	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BSK2_RS08455	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BSK2_RS08455	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BSK2_RS08460	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BSK2_RS08465	COG0631	protein serine/threonine phosphatase activity
BSK2_RS08470	COG2815	serine threonine protein kinase
BSK2_RS08470	COG0515	serine threonine protein kinase
BSK2_RS08475	COG1162	GTPase activity
BSK2_RS08480	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BSK2_RS08485	COG1564	THIamine pyrophosphokinase
BSK2_RS08495	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BSK2_RS08500	COG1302	Protein conserved in bacteria
BSK2_RS08505	COG1461	Dihydroxyacetone kinase
BSK2_RS08510	COG1760	l-serine dehydratase
BSK2_RS08515	COG1760	l-serine dehydratase
BSK2_RS08520	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BSK2_RS08525	COG1349	DNA-binding transcription factor activity
BSK2_RS08525	COG2050	protein possibly involved in aromatic compounds catabolism
BSK2_RS08530	COG0416	fatty acid biosynthetic process
BSK2_RS08535	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BSK2_RS08540	COG1028	Short-chain dehydrogenase reductase Sdr
BSK2_RS08550	COG0571	ribonuclease III activity
BSK2_RS08555	COG1196	nuclear chromosome segregation
BSK2_RS08560	COG0552	protein localization to endoplasmic reticulum
BSK2_RS08570	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BSK2_RS08575	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BSK2_RS08580	COG0228	four-way junction DNA binding
BSK2_RS08585	COG1837	Belongs to the UPF0109 family
BSK2_RS08595	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BSK2_RS08600	COG0336	Belongs to the RNA methyltransferase TrmD family
BSK2_RS08605	COG0335	large ribosomal subunit rRNA binding
BSK2_RS08610	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BSK2_RS08615	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BSK2_RS08625	COG2257	FlhB HrpN YscU SpaS Family
BSK2_RS08630	COG0045	succinate-CoA ligase (ADP-forming) activity
BSK2_RS08635	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BSK2_RS08640	COG0758	DNA mediated transformation
BSK2_RS08645	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BSK2_RS08650	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BSK2_RS08655	COG4974	Belongs to the 'phage' integrase family
BSK2_RS08660	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BSK2_RS08665	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BSK2_RS08670	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BSK2_RS08675	COG1815	bacterial-type flagellum-dependent cell motility
BSK2_RS08680	COG1558	bacterial-type flagellum-dependent cell motility
BSK2_RS08685	COG1677	Flagellar hook-basal body complex protein FliE
BSK2_RS08690	COG1766	The M ring may be actively involved in energy transduction
BSK2_RS08695	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BSK2_RS08700	COG1317	bacterial-type flagellum organization
BSK2_RS08705	COG1157	protein secretion by the type III secretion system
BSK2_RS08710	COG2882	bacterial-type flagellum organization
BSK2_RS08715	COG3334	PFAM MgtE intracellular
BSK2_RS08720	COG3144	bacterial-type flagellum assembly
BSK2_RS08725	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BSK2_RS08730	COG4786	Flagellar basal body rod
BSK2_RS08735	COG1582	Flagellar protein (FlbD)
BSK2_RS08740	COG1580	Controls the rotational direction of flagella during chemotaxis
BSK2_RS08745	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BSK2_RS08750	COG1776	CheC inhibitor of MCP methylation
BSK2_RS08750	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BSK2_RS08755	COG2201	protein-glutamate methylesterase activity
BSK2_RS08760	COG3190	flagellar
BSK2_RS08765	COG1338	Plays a role in the flagellum-specific transport system
BSK2_RS08770	COG1987	bacterial-type flagellum assembly
BSK2_RS08775	COG1684	flagellar biosynthetic protein fliR
BSK2_RS08780	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BSK2_RS08785	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BSK2_RS08790	COG1419	protein localization to endoplasmic reticulum
BSK2_RS08795	COG0455	bacterial-type flagellum organization
BSK2_RS08800	COG2201	protein-glutamate methylesterase activity
BSK2_RS08805	COG2198	Histidine kinase
BSK2_RS08805	COG0643	Histidine kinase
BSK2_RS08810	COG0835	chemotaxis
BSK2_RS08815	COG1776	CheC inhibitor of MCP methylation
BSK2_RS08820	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BSK2_RS08825	COG1191	sigma factor activity
BSK2_RS08835	COG0052	Belongs to the universal ribosomal protein uS2 family
BSK2_RS08840	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BSK2_RS08845	COG0528	UMP kinase activity
BSK2_RS08850	COG0233	cytoplasmic translational termination
BSK2_RS08855	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BSK2_RS08860	COG4589	Belongs to the CDS family
BSK2_RS08865	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BSK2_RS08870	COG0750	zinc metalloprotease
BSK2_RS08875	COG0442	prolyl-tRNA aminoacylation
BSK2_RS08880	COG2176	DNA-directed DNA polymerase activity
BSK2_RS08885	COG0779	Required for maturation of 30S ribosomal subunits
BSK2_RS08890	COG0195	Participates in both transcription termination and antitermination
BSK2_RS08895	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BSK2_RS08900	COG1358	cellular component organization or biogenesis
BSK2_RS08905	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BSK2_RS08910	COG1550	Protein conserved in bacteria
BSK2_RS08915	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BSK2_RS08920	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BSK2_RS08925	COG0196	riboflavin kinase activity
BSK2_RS08930	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BSK2_RS08935	COG1185	polyribonucleotide nucleotidyltransferase activity
BSK2_RS08940	COG0726	polysaccharide deacetylase
BSK2_RS08945	COG0612	Peptidase, M16
BSK2_RS08950	COG1873	PFAM PRC-barrel domain
BSK2_RS08955	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BSK2_RS08960	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BSK2_RS08965	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BSK2_RS08970	COG0527	aspartate kinase activity
BSK2_RS08975	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BSK2_RS08980	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BSK2_RS08985	COG0740	serine-type endopeptidase activity
BSK2_RS08995	COG1674	ftsk spoiiie
BSK2_RS08995	COG4980	gas vesicle protein
BSK2_RS09000	COG2188	Transcriptional regulator
BSK2_RS09005	COG2814	Major facilitator Superfamily
BSK2_RS09010	COG0612	Peptidase, M16
BSK2_RS09015	COG0612	Peptidase, M16
BSK2_RS09020	COG0300	oxidoreductase activity
BSK2_RS09035	COG1426	Protein conserved in bacteria
BSK2_RS09040	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BSK2_RS09045	COG1058	Belongs to the CinA family
BSK2_RS09045	COG1546	Belongs to the CinA family
BSK2_RS09050	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BSK2_RS09055	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BSK2_RS09060	COG1418	mRNA catabolic process
BSK2_RS09065	COG1692	metallophosphoesterase
BSK2_RS09070	COG2359	stage V sporulation protein S
BSK2_RS09075	COG1063	alcohol dehydrogenase
BSK2_RS09080	COG0156	8-amino-7-oxononanoate synthase activity
BSK2_RS09085	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BSK2_RS09090	COG4550	Control of competence regulator ComK, YlbF/YmcA
BSK2_RS09100	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BSK2_RS09105	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BSK2_RS09120	COG3226	Transcriptional regulator
BSK2_RS09125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSK2_RS09135	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BSK2_RS09140	COG3321	synthase
BSK2_RS09145	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BSK2_RS09145	COG2070	2-Nitropropane dioxygenase
BSK2_RS09150	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BSK2_RS09155	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BSK2_RS09160	COG3425	synthase
BSK2_RS09165	COG1024	Enoyl-CoA hydratase
BSK2_RS09170	COG1024	Enoyl-CoA hydratase
BSK2_RS09175	COG3321	synthase
BSK2_RS09175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BSK2_RS09175	COG0318	PFAM AMP-dependent synthetase and ligase
BSK2_RS09175	COG0300	oxidoreductase activity
BSK2_RS09175	COG1028	Short-chain dehydrogenase reductase Sdr
BSK2_RS09180	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BSK2_RS09180	COG4221	oxidoreductase activity
BSK2_RS09180	COG3321	synthase
BSK2_RS09180	COG0300	oxidoreductase activity
BSK2_RS09185	COG3321	synthase
BSK2_RS09185	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BSK2_RS09185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BSK2_RS09185	COG1028	Short-chain dehydrogenase reductase Sdr
BSK2_RS09185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BSK2_RS09190	COG3321	synthase
BSK2_RS09190	COG1028	Short-chain dehydrogenase reductase Sdr
BSK2_RS09190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BSK2_RS09190	COG4221	oxidoreductase activity
BSK2_RS09195	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BSK2_RS09195	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BSK2_RS09195	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BSK2_RS09195	COG3321	synthase
BSK2_RS09200	COG2124	cytochrome p450
BSK2_RS09210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSK2_RS09215	COG1404	Belongs to the peptidase S8 family
BSK2_RS09225	COG4195	phage-related replication protein
BSK2_RS09230	COG1764	response to oxidative stress
BSK2_RS09235	COG2076	Multidrug Resistance protein
BSK2_RS09240	COG2076	Multidrug Resistance protein
BSK2_RS09255	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BSK2_RS09260	COG1923	regulation of RNA biosynthetic process
BSK2_RS09275	COG1780	Probably involved in ribonucleotide reductase function
BSK2_RS09280	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BSK2_RS09285	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BSK2_RS09290	COG4112	unkown
BSK2_RS09295	COG0860	N-Acetylmuramoyl-L-alanine amidase
BSK2_RS09305	COG0464	growth
BSK2_RS09310	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BSK2_RS09315	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BSK2_RS09320	COG0789	Transcriptional regulator
BSK2_RS09325	COG0174	glutamine synthetase
BSK2_RS09360	COG0463	Glycosyl transferase, family 2
BSK2_RS09380	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BSK2_RS09405	COG0135	phosphoribosylanthranilate isomerase activity
BSK2_RS09410	COG2211	Major facilitator Superfamily
BSK2_RS09415	COG3507	Belongs to the glycosyl hydrolase 43 family
BSK2_RS09420	COG1940	carbohydrate kinase activity
BSK2_RS09425	COG2115	Belongs to the xylose isomerase family
BSK2_RS09430	COG1070	Carbohydrate kinase
BSK2_RS09440	COG1525	nuclease
BSK2_RS09445	COG2814	Major facilitator Superfamily
BSK2_RS09450	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BSK2_RS09460	COG0756	dUTP diphosphatase activity
BSK2_RS09470	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BSK2_RS09505	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BSK2_RS09515	COG3832	glyoxalase III activity
BSK2_RS09525	COG0697	spore germination
BSK2_RS09530	COG0531	amino acid
BSK2_RS09560	COG4195	phage-related replication protein
BSK2_RS09570	COG0346	lactoylglutathione lyase activity
BSK2_RS09580	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BSK2_RS09585	COG1388	LysM domain
BSK2_RS09590	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BSK2_RS09595	COG4224	UPF0291 protein
BSK2_RS09600	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BSK2_RS09610	COG3763	UPF0154 protein
BSK2_RS09620	COG0785	Cytochrome C biogenesis protein
BSK2_RS09625	COG2201	protein-glutamate methylesterase activity
BSK2_RS09630	COG4846	Membrane protein involved in cytochrome C biogenesis
BSK2_RS09640	COG0071	Belongs to the small heat shock protein (HSP20) family
BSK2_RS09655	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BSK2_RS09660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSK2_RS09680	COG0824	Thioesterase
BSK2_RS09690	COG4841	protein insertion into membrane
BSK2_RS09695	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BSK2_RS09700	COG1832	CoA-binding protein
BSK2_RS09705	COG0187	DNA topoisomerase II activity
BSK2_RS09710	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BSK2_RS09720	COG1115	amino acid carrier protein
BSK2_RS09725	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BSK2_RS09735	COG5520	Belongs to the glycosyl hydrolase 30 family
BSK2_RS09740	COG3507	Belongs to the glycosyl hydrolase 43 family
BSK2_RS09750	COG2246	polysaccharide biosynthetic process
BSK2_RS09755	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BSK2_RS09760	COG0586	Pfam SNARE associated Golgi protein
BSK2_RS09765	COG2404	hydrolase activity, acting on ester bonds
BSK2_RS09770	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BSK2_RS09775	COG1024	Enoyl-CoA hydratase
BSK2_RS09780	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BSK2_RS09785	COG0511	ligase activity, forming carbon-carbon bonds
BSK2_RS09790	COG0439	Biotin carboxylase
BSK2_RS09795	COG0318	PFAM AMP-dependent synthetase and ligase
BSK2_RS09800	COG1960	acyl-CoA dehydrogenase activity
BSK2_RS09810	COG1649	PFAM Uncharacterised BCR, COG1649
BSK2_RS09820	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BSK2_RS09820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BSK2_RS09825	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BSK2_RS09830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BSK2_RS09835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BSK2_RS09840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BSK2_RS09845	COG2027	D-alanyl-D-alanine carboxypeptidase
BSK2_RS09850	COG2017	converts alpha-aldose to the beta-anomer
BSK2_RS09855	COG0534	Mate efflux family protein
BSK2_RS09870	COG0582	viral genome integration into host DNA
BSK2_RS09875	COG0166	Belongs to the GPI family
BSK2_RS09880	COG0405	Gamma-glutamyltransferase
BSK2_RS09885	COG0583	DNA-binding transcription factor activity
BSK2_RS09890	COG0604	alcohol dehydrogenase
BSK2_RS09895	COG0493	'glutamate synthase
BSK2_RS09900	COG0069	glutamate synthase activity
BSK2_RS09900	COG0070	glutamate synthase
BSK2_RS09900	COG0067	glutamate synthase
BSK2_RS09905	COG0583	DNA-binding transcription factor activity
BSK2_RS09910	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BSK2_RS09915	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BSK2_RS09925	COG0300	oxidoreductase activity
BSK2_RS09930	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BSK2_RS09940	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BSK2_RS09945	COG2814	Major facilitator Superfamily
BSK2_RS09950	COG1070	Carbohydrate kinase
BSK2_RS09955	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BSK2_RS09960	COG0243	molybdopterin cofactor binding
BSK2_RS09985	COG5278	phosphoserine phosphatase activity
BSK2_RS09985	COG0840	transmembrane signaling receptor activity
BSK2_RS09990	COG2368	4-hydroxyphenylacetate
BSK2_RS09995	COG4305	rare lipoprotein A
BSK2_RS10000	COG3619	membrane
BSK2_RS10005	COG3866	Pectate lyase
BSK2_RS10010	COG2135	peptidase activity
BSK2_RS10020	COG2140	Oxalate decarboxylase
BSK2_RS10030	COG0456	acetyltransferase
BSK2_RS10050	COG2720	vancomycin resistance protein
BSK2_RS10060	COG3655	Transcriptional regulator
BSK2_RS10065	COG3739	integral membrane protein
BSK2_RS10070	COG0583	DNA-binding transcription factor activity
BSK2_RS10075	COG0697	spore germination
BSK2_RS10085	COG0693	protein deglycase activity
BSK2_RS10090	COG2367	Beta-lactamase
BSK2_RS10095	COG4282	regulation of fungal-type cell wall biogenesis
BSK2_RS10115	COG0574	Belongs to the PEP-utilizing enzyme family
BSK2_RS10115	COG3848	Pyruvate phosphate dikinase
BSK2_RS10120	COG0726	polysaccharide deacetylase
BSK2_RS10130	COG2314	TM2 domain
BSK2_RS10135	COG1396	sequence-specific DNA binding
BSK2_RS10170	COG1793	dna ligase
BSK2_RS10210	COG1388	LysM domain
BSK2_RS10240	COG0457	Tetratricopeptide repeat
BSK2_RS10275	COG0457	Tetratricopeptide repeat
BSK2_RS10290	COG5444	nuclease activity
BSK2_RS10295	COG4282	regulation of fungal-type cell wall biogenesis
BSK2_RS10300	COG1231	oxidoreductase activity
BSK2_RS10305	COG5434	Belongs to the glycosyl hydrolase 28 family
BSK2_RS10310	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BSK2_RS10315	COG0662	Cupin 2, conserved barrel domain protein
BSK2_RS10315	COG2207	Transcriptional regulator
BSK2_RS10320	COG0456	acetyltransferase
BSK2_RS10325	COG1309	transcriptional regulator
BSK2_RS10330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSK2_RS10335	COG3708	Transcriptional regulator
BSK2_RS10340	COG2378	regulation of single-species biofilm formation
BSK2_RS10350	COG0640	Transcriptional regulator
BSK2_RS10355	COG0741	lytic transglycosylase activity
BSK2_RS10360	COG2322	membrane
BSK2_RS10380	COG3239	Fatty acid desaturase
BSK2_RS10385	COG4585	Histidine kinase
BSK2_RS10390	COG2197	response regulator
BSK2_RS10395	COG3584	3D domain protein
BSK2_RS10395	COG1388	LysM domain
BSK2_RS10400	COG0514	ATP-dependent DNA helicase (RecQ)
BSK2_RS10410	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BSK2_RS10415	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BSK2_RS10430	COG0071	Belongs to the small heat shock protein (HSP20) family
BSK2_RS10455	COG1012	belongs to the aldehyde dehydrogenase family
BSK2_RS10460	COG1657	PFAM Prenyltransferase squalene oxidase
BSK2_RS10465	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BSK2_RS10470	COG0733	neurotransmitter:sodium symporter activity
BSK2_RS10475	COG0385	Bile acid
BSK2_RS10480	COG0508	dehydrogenase complex catalyzes the overall conversion of
BSK2_RS10485	COG0567	Dehydrogenase, E1 component
BSK2_RS10490	COG4548	von Willebrand factor, type A
BSK2_RS10495	COG0714	Associated with various cellular activities
BSK2_RS10500	COG2032	superoxide dismutase activity
BSK2_RS10505	COG0791	NLP P60 protein
BSK2_RS10505	COG1388	LysM domain
BSK2_RS10510	COG1819	glycosyl
BSK2_RS10515	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BSK2_RS10520	COG0534	Mate efflux family protein
BSK2_RS10525	COG1366	Belongs to the anti-sigma-factor antagonist family
BSK2_RS10530	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BSK2_RS10535	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BSK2_RS10545	COG2962	Rard protein
BSK2_RS10560	COG2610	gluconate transmembrane transporter activity
BSK2_RS10565	COG1942	4-Oxalocrotonate Tautomerase
BSK2_RS10570	COG1733	regulation of RNA biosynthetic process
BSK2_RS10575	COG0778	Nitroreductase
BSK2_RS10580	COG0400	carboxylic ester hydrolase activity
BSK2_RS10585	COG0346	lactoylglutathione lyase activity
BSK2_RS10595	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BSK2_RS10600	COG0793	Belongs to the peptidase S41A family
BSK2_RS10600	COG3409	Peptidoglycan-binding domain 1 protein
BSK2_RS10605	COG2226	methyltransferase
BSK2_RS10615	COG1876	peptidase activity
BSK2_RS10620	COG0813	purine-nucleoside phosphorylase activity
BSK2_RS10635	COG0671	phosphoesterase, PA-phosphatase related
BSK2_RS10660	COG4479	Belongs to the UPF0346 family
BSK2_RS10670	COG1509	lysine 2,3-aminomutase activity
BSK2_RS10675	COG0456	acetyltransferase
BSK2_RS10680	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BSK2_RS10685	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BSK2_RS10690	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BSK2_RS10695	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BSK2_RS10705	COG0456	acetyltransferase
BSK2_RS10710	COG0463	Glycosyl transferase, family 2
BSK2_RS10725	COG4641	Protein conserved in bacteria
BSK2_RS10730	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
BSK2_RS10735	COG1086	Polysaccharide biosynthesis protein
BSK2_RS10740	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BSK2_RS10745	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BSK2_RS10750	COG1846	Transcriptional regulator
BSK2_RS10755	COG0534	Mate efflux family protein
BSK2_RS10765	COG4698	Protein conserved in bacteria
BSK2_RS10770	COG2755	lipolytic protein G-D-S-L family
BSK2_RS10775	COG1999	signal sequence binding
BSK2_RS10785	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BSK2_RS10790	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BSK2_RS10795	COG1272	protein, Hemolysin III
BSK2_RS10800	COG0204	Acyl-transferase
BSK2_RS10805	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BSK2_RS10810	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BSK2_RS10815	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BSK2_RS10825	COG2136	Putative SAM-dependent methyltransferase
BSK2_RS10825	COG2521	methyltransferase
BSK2_RS10835	COG0129	dihydroxy-acid dehydratase activity
BSK2_RS10840	COG1413	lyase activity
BSK2_RS10845	COG1418	mRNA catabolic process
BSK2_RS10850	COG0386	Belongs to the glutathione peroxidase family
BSK2_RS10855	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BSK2_RS10860	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BSK2_RS10865	COG1278	Cold shock
BSK2_RS10885	COG0328	RNA-DNA hybrid ribonuclease activity
BSK2_RS10890	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BSK2_RS10895	COG0328	RNA-DNA hybrid ribonuclease activity
BSK2_RS10905	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BSK2_RS10920	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BSK2_RS10930	COG1755	Isoprenylcysteine carboxyl methyltransferase
BSK2_RS10935	COG3424	synthase
BSK2_RS10940	COG2233	PERMEase
BSK2_RS10945	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BSK2_RS10950	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BSK2_RS10960	COG0800	Aldolase
BSK2_RS10965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BSK2_RS10970	COG1609	Transcriptional regulator
BSK2_RS10975	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BSK2_RS10980	COG1028	Short-chain dehydrogenase reductase Sdr
BSK2_RS10985	COG1199	ATP-dependent helicase activity
BSK2_RS11000	COG0116	Belongs to the methyltransferase superfamily
BSK2_RS11015	COG4474	Belongs to the UPF0398 family
BSK2_RS11025	COG3359	exonuclease
BSK2_RS11030	COG1205	dead DEAH box helicase
BSK2_RS11030	COG1111	helicase
BSK2_RS11035	COG2190	(PTS) system
BSK2_RS11040	COG0071	Belongs to the small heat shock protein (HSP20) family
BSK2_RS11075	COG3331	DNA recombination
BSK2_RS11080	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BSK2_RS11080	COG4499	WXG100 protein secretion system (Wss), protein YukC
BSK2_RS11090	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BSK2_RS11095	COG3935	DnaD domain protein
BSK2_RS11100	COG0017	Asparaginyl-tRNA synthetase
BSK2_RS11105	COG0436	Aminotransferase
BSK2_RS11110	COG5353	protein conserved in bacteria
BSK2_RS11120	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BSK2_RS11120	COG1199	ATP-dependent helicase activity
BSK2_RS11125	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BSK2_RS11130	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BSK2_RS11135	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BSK2_RS11140	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BSK2_RS11140	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BSK2_RS11145	COG0617	tRNA 3'-terminal CCA addition
BSK2_RS11150	COG0438	transferase activity, transferring glycosyl groups
BSK2_RS11155	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BSK2_RS11160	COG1803	Methylglyoxal synthase
BSK2_RS11165	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BSK2_RS11170	COG1694	Mazg nucleotide pyrophosphohydrolase
BSK2_RS11175	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BSK2_RS11185	COG4347	Protein of unknown function (DUF1405)
BSK2_RS11190	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BSK2_RS11190	COG2010	Cytochrome c
BSK2_RS11195	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BSK2_RS11200	COG0723	plastoquinol--plastocyanin reductase activity
BSK2_RS11210	COG5582	Belongs to the UPF0302 family
BSK2_RS11215	COG0457	Tetratricopeptide repeat
BSK2_RS11220	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BSK2_RS11225	COG0287	Prephenate dehydrogenase
BSK2_RS11240	COG0133	tryptophan synthase activity
BSK2_RS11245	COG0135	phosphoribosylanthranilate isomerase activity
BSK2_RS11255	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BSK2_RS11260	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BSK2_RS11265	COG4401	Chorismate mutase type I
BSK2_RS11270	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BSK2_RS11275	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BSK2_RS11280	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BSK2_RS11285	COG0105	UTP biosynthetic process
BSK2_RS11290	COG0142	geranyltranstransferase activity
BSK2_RS11295	COG2226	methyltransferase
BSK2_RS11300	COG0142	geranyltranstransferase activity
BSK2_RS11310	COG0302	gtp cyclohydrolase
BSK2_RS11315	COG0776	regulation of translation
BSK2_RS11320	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BSK2_RS11335	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BSK2_RS11340	COG1160	GTP binding
BSK2_RS11365	COG1304	FMN binding
BSK2_RS11370	COG0539	negative regulation of cytoplasmic translation
BSK2_RS11375	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BSK2_RS11385	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BSK2_RS11390	COG2959	enzyme of heme biosynthesis
BSK2_RS11395	COG3409	Peptidoglycan-binding domain 1 protein
BSK2_RS11395	COG3773	Cell wall hydrolase
BSK2_RS11400	COG2339	peptidase activity
BSK2_RS11405	COG0492	ferredoxin-NADP+ reductase activity
BSK2_RS11410	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BSK2_RS11415	COG4862	establishment of competence for transformation
BSK2_RS11420	COG1408	metallophosphoesterase
BSK2_RS11430	COG1388	LysM domain
BSK2_RS11435	COG1266	CAAX protease self-immunity
BSK2_RS11440	COG0514	ATP-dependent DNA helicase (RecQ)
BSK2_RS11445	COG4955	Helix-turn-helix domain
BSK2_RS11450	COG1141	Ferredoxin
BSK2_RS11455	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BSK2_RS11460	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BSK2_RS11465	COG0710	3-dehydroquinate dehydratase activity
BSK2_RS11475	COG1595	DNA-templated transcription, initiation
BSK2_RS11480	COG5002	protein histidine kinase activity
BSK2_RS11485	COG0745	RESPONSE REGULATOR receiver
BSK2_RS11490	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BSK2_RS11495	COG1333	cytochrome c biogenesis protein
BSK2_RS11500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSK2_RS11505	COG1187	pseudouridine synthase activity
BSK2_RS11510	COG0700	Nucleoside recognition
BSK2_RS11515	COG2715	membrane protein required for spore maturation
BSK2_RS11520	COG1686	Belongs to the peptidase S11 family
BSK2_RS11530	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BSK2_RS11535	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BSK2_RS11540	COG1547	Domain of unknown function (DUF309)
BSK2_RS11545	COG0456	acetyltransferase
BSK2_RS11550	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BSK2_RS11555	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BSK2_RS11555	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BSK2_RS11560	COG0307	riboflavin synthase, alpha
BSK2_RS11565	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BSK2_RS11565	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BSK2_RS11575	COG0681	Belongs to the peptidase S26 family
BSK2_RS11590	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
BSK2_RS11620	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BSK2_RS11625	COG0741	lytic transglycosylase activity
BSK2_RS11625	COG0739	heme binding
BSK2_RS11625	COG1196	nuclear chromosome segregation
BSK2_RS11670	COG0457	Tetratricopeptide repeat
BSK2_RS11675	COG5444	nuclease activity
BSK2_RS11715	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BSK2_RS11720	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BSK2_RS11730	COG4086	secreted protein
BSK2_RS11735	COG0019	diaminopimelate decarboxylase activity
BSK2_RS11740	COG0697	spore germination
BSK2_RS11755	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BSK2_RS11775	COG1191	sigma factor activity
BSK2_RS11780	COG2172	sigma factor antagonist activity
BSK2_RS11785	COG1366	Belongs to the anti-sigma-factor antagonist family
BSK2_RS11790	COG1686	Belongs to the peptidase S11 family
BSK2_RS11795	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BSK2_RS11800	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BSK2_RS11805	COG4974	Belongs to the 'phage' integrase family
BSK2_RS11815	COG0735	belongs to the Fur family
BSK2_RS11820	COG1300	Membrane
BSK2_RS11830	COG0281	malic enzyme
BSK2_RS11835	COG1757	Na H antiporter
BSK2_RS11840	COG1027	Aspartate ammonia-lyase
BSK2_RS11845	COG0252	asparaginase activity
BSK2_RS11850	COG1396	sequence-specific DNA binding
BSK2_RS11855	COG1379	DNA repair
BSK2_RS11860	COG0494	nUDIX hydrolase
BSK2_RS11870	COG0667	Aldo Keto reductase
BSK2_RS11880	COG1073	alpha beta
BSK2_RS11890	COG4918	Iron-sulphur cluster biosynthesis
BSK2_RS11895	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BSK2_RS11895	COG0456	acetyltransferase
BSK2_RS11900	COG2329	Antibiotic biosynthesis monooxygenase
BSK2_RS11905	COG0456	acetyltransferase
BSK2_RS11915	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BSK2_RS11925	COG2211	Major facilitator Superfamily
BSK2_RS11935	COG0346	lactoylglutathione lyase activity
BSK2_RS11940	COG1072	(Pantothenic acid kinase))
BSK2_RS11945	COG3048	D-serine ammonia-lyase activity
BSK2_RS11950	COG0300	oxidoreductase activity
BSK2_RS11955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSK2_RS11960	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BSK2_RS11965	COG4187	Peptidase family M20/M25/M40
BSK2_RS11970	COG1902	pentaerythritol trinitrate reductase activity
BSK2_RS11975	COG0596	Alpha beta hydrolase
BSK2_RS11985	COG1234	tRNA 3'-trailer cleavage
BSK2_RS11990	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BSK2_RS11995	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BSK2_RS12000	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BSK2_RS12010	COG0706	membrane insertase activity
BSK2_RS12015	COG3361	conserved protein (COG2071)
BSK2_RS12020	COG2195	Cleaves the N-terminal amino acid of tripeptides
BSK2_RS12025	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BSK2_RS12030	COG0346	lactoylglutathione lyase activity
BSK2_RS12035	COG1376	ErfK ybiS ycfS ynhG family protein
BSK2_RS12040	COG4129	membrane
BSK2_RS12045	COG1126	abc transporter atp-binding protein
BSK2_RS12050	COG0765	amino acid transport
BSK2_RS12055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSK2_RS12065	COG1597	lipid kinase activity
BSK2_RS12070	COG2814	Major facilitator Superfamily
BSK2_RS12075	COG0789	Transcriptional regulator
BSK2_RS12075	COG4978	Transcriptional regulator
BSK2_RS12080	COG0508	dehydrogenase complex catalyzes the overall conversion of
BSK2_RS12085	COG0022	dehydrogenase e1 component
BSK2_RS12095	COG3426	butyrate kinase activity
BSK2_RS12100	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BSK2_RS12105	COG0280	phosphate acetyltransferase
BSK2_RS12110	COG3290	protein histidine kinase activity
BSK2_RS12110	COG3829	transcription factor binding
BSK2_RS12120	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BSK2_RS12125	COG2079	MmgE PrpD family protein
BSK2_RS12130	COG0372	Belongs to the citrate synthase family
BSK2_RS12135	COG1960	acyl-CoA dehydrogenase activity
BSK2_RS12140	COG1250	3-hydroxyacyl-CoA dehydrogenase
BSK2_RS12145	COG0183	Belongs to the thiolase family
BSK2_RS12150	COG0584	glycerophosphoryl diester phosphodiesterase
BSK2_RS12155	COG0860	N-Acetylmuramoyl-L-alanine amidase
BSK2_RS12165	COG1902	pentaerythritol trinitrate reductase activity
BSK2_RS12170	COG0745	RESPONSE REGULATOR receiver
BSK2_RS12175	COG0750	zinc metalloprotease
BSK2_RS12180	COG0497	DNA recombination
BSK2_RS12185	COG1438	arginine binding
BSK2_RS12190	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BSK2_RS12195	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BSK2_RS12200	COG0142	geranyltranstransferase activity
BSK2_RS12205	COG1722	exodeoxyribonuclease VII activity
BSK2_RS12210	COG1570	exodeoxyribonuclease VII activity
BSK2_RS12215	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BSK2_RS12220	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BSK2_RS12225	COG1302	Protein conserved in bacteria
BSK2_RS12230	COG0439	Biotin carboxylase
BSK2_RS12235	COG0511	ligase activity, forming carbon-carbon bonds
BSK2_RS12275	COG3854	ATPases associated with a variety of cellular activities
BSK2_RS12285	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BSK2_RS12290	COG0006	proline dipeptidase activity
BSK2_RS12295	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BSK2_RS12305	COG3872	metal-dependent enzyme
BSK2_RS12315	COG1752	Esterase of the alpha-beta hydrolase superfamily
BSK2_RS12320	COG1321	iron dependent repressor
BSK2_RS12325	COG0095	Lipoate-protein ligase
BSK2_RS12330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BSK2_RS12335	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BSK2_RS12340	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BSK2_RS12345	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BSK2_RS12350	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BSK2_RS12365	COG1396	sequence-specific DNA binding
BSK2_RS12375	COG0681	Belongs to the peptidase S26 family
BSK2_RS12400	COG4940	Competence protein ComGF
BSK2_RS12410	COG4970	Tfp pilus assembly protein FimT
BSK2_RS12415	COG4537	Required for transformation and DNA binding
BSK2_RS12420	COG1459	type II secretion system
BSK2_RS12425	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BSK2_RS12435	COG0598	Magnesium transport protein CorA
BSK2_RS12440	COG1253	flavin adenine dinucleotide binding
BSK2_RS12445	COG1366	Belongs to the anti-sigma-factor antagonist family
BSK2_RS12455	COG1393	Belongs to the ArsC family
BSK2_RS12465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSK2_RS12475	COG0011	TIGRFAM Protein of
BSK2_RS12485	COG2866	Carboxypeptidase
BSK2_RS12490	COG1368	sulfuric ester hydrolase activity
BSK2_RS12495	COG1940	carbohydrate kinase activity
BSK2_RS12500	COG4483	Protein conserved in bacteria
BSK2_RS12505	COG0457	Tetratricopeptide repeat
BSK2_RS12505	COG0705	Rhomboid family
BSK2_RS12515	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BSK2_RS12525	COG0438	transferase activity, transferring glycosyl groups
BSK2_RS12540	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BSK2_RS12545	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BSK2_RS12550	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BSK2_RS12555	COG0581	inorganic phosphate transmembrane transporter activity
BSK2_RS12560	COG0573	inorganic phosphate transmembrane transporter activity
BSK2_RS12565	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BSK2_RS12570	COG0768	penicillin binding
BSK2_RS12575	COG0477	Major facilitator Superfamily
BSK2_RS12580	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BSK2_RS12585	COG2839	Protein conserved in bacteria
BSK2_RS12590	COG5521	maltodextrose utilization protein MalA
BSK2_RS12595	COG1388	LysM domain
BSK2_RS12600	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BSK2_RS12605	COG4709	membrane
BSK2_RS12610	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BSK2_RS12615	COG0735	belongs to the Fur family
BSK2_RS12620	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BSK2_RS12630	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BSK2_RS12635	COG0513	Belongs to the DEAD box helicase family
BSK2_RS12645	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BSK2_RS12650	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BSK2_RS12655	COG2384	SAM-dependent methyltransferase
BSK2_RS12660	COG2010	Cytochrome c
BSK2_RS12670	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BSK2_RS12675	COG0358	DNA primase activity
BSK2_RS12680	COG1671	Belongs to the UPF0178 family
BSK2_RS12685	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BSK2_RS12690	COG0517	IMP dehydrogenase activity
BSK2_RS12695	COG0751	glycine-tRNA ligase activity
BSK2_RS12700	COG0752	glycyl-tRNA synthetase alpha subunit
BSK2_RS12705	COG1381	Involved in DNA repair and RecF pathway recombination
BSK2_RS12715	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BSK2_RS12720	COG0295	cytidine deaminase activity
BSK2_RS12725	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BSK2_RS12730	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BSK2_RS12735	COG1480	7TM receptor with intracellular HD hydrolase
BSK2_RS12740	COG1702	phosphate starvation-inducible protein PhoH
BSK2_RS12745	COG0561	phosphatase activity
BSK2_RS12760	COG4864	UPF0365 protein
BSK2_RS12765	COG1030	water channel activity
BSK2_RS12770	COG1610	YqeY-like protein
BSK2_RS12780	COG1283	sodium-dependent phosphate transmembrane transporter activity
BSK2_RS12785	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BSK2_RS12790	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BSK2_RS12795	COG2264	protein methyltransferase activity
BSK2_RS12800	COG0484	heat shock protein binding
BSK2_RS12805	COG0443	Heat shock 70 kDa protein
BSK2_RS12810	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BSK2_RS12815	COG1420	regulation of RNA biosynthetic process
BSK2_RS12820	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BSK2_RS12825	COG0481	GTPase activity
BSK2_RS12835	COG0860	N-Acetylmuramoyl-L-alanine amidase
BSK2_RS12840	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BSK2_RS12845	COG0268	Binds directly to 16S ribosomal RNA
BSK2_RS12850	COG1466	dna polymerase III delta subunit
BSK2_RS12860	COG0658	competence protein
BSK2_RS12860	COG2333	competence protein COMEC
BSK2_RS12865	COG2131	deaminase
BSK2_RS12870	COG1596	polysaccharide export
BSK2_RS12870	COG1555	photosystem II stabilization
BSK2_RS12875	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BSK2_RS12880	COG2226	methyltransferase
BSK2_RS12885	COG0799	negative regulation of ribosome biogenesis
BSK2_RS12890	COG1713	HD superfamily hydrolase involved in NAD metabolism
BSK2_RS12895	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BSK2_RS12900	COG1534	Rna-binding protein
BSK2_RS12905	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BSK2_RS12910	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BSK2_RS12915	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BSK2_RS12925	COG2755	lipolytic protein G-D-S-L family
BSK2_RS12930	COG3409	Peptidoglycan-binding domain 1 protein
BSK2_RS12930	COG5632	N-Acetylmuramoyl-L-alanine amidase
BSK2_RS12935	COG0398	Pfam SNARE associated Golgi protein
BSK2_RS12940	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BSK2_RS12950	COG3209	COG3209 Rhs family protein
BSK2_RS12960	COG1846	Transcriptional regulator
BSK2_RS12965	COG0477	Major facilitator Superfamily
BSK2_RS12970	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BSK2_RS12980	COG4124	Belongs to the glycosyl hydrolase 26 family
BSK2_RS12995	COG2808	Putative FMN-binding domain
BSK2_RS13000	COG0456	acetyltransferase
BSK2_RS13005	COG1846	Transcriptional regulator
BSK2_RS13010	COG2364	Membrane
BSK2_RS13020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BSK2_RS13030	COG0457	Tetratricopeptide repeat
BSK2_RS13035	COG5444	nuclease activity
BSK2_RS13045	COG5632	N-Acetylmuramoyl-L-alanine amidase
BSK2_RS13045	COG3409	Peptidoglycan-binding domain 1 protein
BSK2_RS13050	COG4824	toxin secretion phage lysis holin
BSK2_RS13055	COG1783	phage Terminase large subunit
BSK2_RS13060	COG5484	DNA packaging
BSK2_RS13080	COG3677	Transposase
BSK2_RS13125	COG0563	adenylate kinase activity
BSK2_RS13130	COG2856	Zn peptidase
BSK2_RS13150	COG4124	Belongs to the glycosyl hydrolase 26 family
BSK2_RS13155	COG0730	response to heat
BSK2_RS13160	COG0425	Belongs to the sulfur carrier protein TusA family
BSK2_RS13175	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BSK2_RS13175	COG0425	Belongs to the sulfur carrier protein TusA family
BSK2_RS13185	COG2210	Belongs to the sulfur carrier protein TusA family
BSK2_RS13190	COG1937	Protein conserved in bacteria
BSK2_RS13205	COG0662	Cupin 2, conserved barrel domain protein
BSK2_RS13220	COG5632	N-Acetylmuramoyl-L-alanine amidase
BSK2_RS13220	COG3409	Peptidoglycan-binding domain 1 protein
BSK2_RS13225	COG0789	Transcriptional regulator
BSK2_RS13225	COG4978	Transcriptional regulator
BSK2_RS13230	COG2814	Major facilitator Superfamily
BSK2_RS13235	COG0456	acetyltransferase
BSK2_RS13240	COG1253	flavin adenine dinucleotide binding
BSK2_RS13255	COG0583	DNA-binding transcription factor activity
BSK2_RS13260	COG2072	flavoprotein involved in K transport
BSK2_RS13265	COG1230	cation diffusion facilitator family transporter
BSK2_RS13270	COG1942	4-Oxalocrotonate Tautomerase
BSK2_RS13275	COG0583	DNA-binding transcription factor activity
BSK2_RS13285	COG1114	Component of the transport system for branched-chain amino acids
BSK2_RS13290	COG1687	branched-chain amino acid
BSK2_RS13295	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BSK2_RS13300	COG1522	sequence-specific DNA binding
BSK2_RS13305	COG2732	(Barnase) inhibitor
BSK2_RS13310	COG2124	cytochrome p450
BSK2_RS13325	COG1335	isochorismatase
BSK2_RS13335	COG2318	DinB family
BSK2_RS13345	COG2070	2-Nitropropane dioxygenase
BSK2_RS13360	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BSK2_RS13375	COG3443	Belongs to the bacterial solute-binding protein 9 family
BSK2_RS13380	COG1595	DNA-templated transcription, initiation
BSK2_RS13385	COG0667	Aldo Keto reductase
BSK2_RS13390	COG2851	Citrate transporter
BSK2_RS13395	COG0583	DNA-binding transcription factor activity
BSK2_RS13400	COG2828	Protein conserved in bacteria
BSK2_RS13405	COG3409	Peptidoglycan-binding domain 1 protein
BSK2_RS13410	COG5566	PFAM Mor transcription activator
BSK2_RS13415	COG0596	Alpha beta hydrolase
BSK2_RS13420	COG4991	sh3 domain protein
BSK2_RS13425	COG4991	sh3 domain protein
BSK2_RS13430	COG0346	lactoylglutathione lyase activity
BSK2_RS13440	COG5577	PFAM Coat F domain
BSK2_RS13445	COG1063	alcohol dehydrogenase
BSK2_RS13455	COG5577	PFAM Coat F domain
BSK2_RS13460	COG0789	Transcriptional regulator
BSK2_RS13470	COG1064	alcohol dehydrogenase
BSK2_RS13475	COG0693	protein deglycase activity
BSK2_RS13480	COG1621	beta-fructofuranosidase activity
BSK2_RS13485	COG3716	PTS system mannose fructose sorbose family IID component
BSK2_RS13490	COG3715	PTS system
BSK2_RS13495	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BSK2_RS13500	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BSK2_RS13505	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BSK2_RS13505	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BSK2_RS13510	COG1113	amino acid transport
BSK2_RS13515	COG1280	lysine exporter protein (LysE YggA)
BSK2_RS13520	COG1378	Sugar-specific transcriptional regulator TrmB
BSK2_RS13525	COG1595	DNA-templated transcription, initiation
BSK2_RS13535	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BSK2_RS13535	COG2755	lipolytic protein G-D-S-L family
BSK2_RS13545	COG2124	cytochrome p450
BSK2_RS13545	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BSK2_RS13550	COG1309	transcriptional regulator
BSK2_RS13555	COG2226	methyltransferase
BSK2_RS13565	COG2116	formate transmembrane transporter activity
BSK2_RS13570	COG5609	conserved protein (DUF2294)
BSK2_RS13575	COG3383	formate dehydrogenase (NAD+) activity
BSK2_RS13580	COG2427	Protein of unknown function (DUF1641)
BSK2_RS13590	COG0626	cystathionine gamma-synthase activity
BSK2_RS13595	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BSK2_RS13600	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BSK2_RS13605	COG2226	methyltransferase
BSK2_RS13620	COG0768	penicillin binding
BSK2_RS13625	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BSK2_RS13630	COG0572	uridine kinase
BSK2_RS13635	COG0826	peptidase U32
BSK2_RS13640	COG0826	peptidase U32
BSK2_RS13645	COG4122	O-methyltransferase activity
BSK2_RS13650	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BSK2_RS13655	COG3906	Belongs to the UPF0473 family
BSK2_RS13660	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BSK2_RS13665	COG4472	Bacterial protein of unknown function (DUF965)
BSK2_RS13670	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BSK2_RS13675	COG0628	permease
BSK2_RS13680	COG1126	abc transporter atp-binding protein
BSK2_RS13685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSK2_RS13690	COG0765	amino acid transport
BSK2_RS13695	COG0765	amino acid transport
BSK2_RS13710	COG3881	PFAM PRC-barrel domain
BSK2_RS13715	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BSK2_RS13720	COG0457	Tetratricopeptide repeat
BSK2_RS13725	COG0482	sulfurtransferase activity
BSK2_RS13730	COG1104	cysteine desulfurase activity
BSK2_RS13735	COG1959	2 iron, 2 sulfur cluster binding
BSK2_RS13740	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BSK2_RS13745	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BSK2_RS13755	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BSK2_RS13760	COG0124	histidyl-tRNA synthetase
BSK2_RS13770	COG4991	sh3 domain protein
BSK2_RS13770	COG0860	N-Acetylmuramoyl-L-alanine amidase
BSK2_RS13770	COG3103	Sh3 type 3 domain protein
BSK2_RS13775	COG1490	D-aminoacyl-tRNA deacylase activity
BSK2_RS13780	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BSK2_RS13785	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BSK2_RS13790	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BSK2_RS13790	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BSK2_RS13795	COG5416	Lipopolysaccharide assembly protein A domain
BSK2_RS13800	COG0490	domain, Protein
BSK2_RS13805	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BSK2_RS13805	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BSK2_RS13815	COG2244	polysaccharide biosynthetic process
BSK2_RS13820	COG2323	membrane
BSK2_RS13830	COG1862	Preprotein translocase
BSK2_RS13835	COG0343	queuine tRNA-ribosyltransferase activity
BSK2_RS13840	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BSK2_RS13850	COG2255	four-way junction helicase activity
BSK2_RS13855	COG0632	four-way junction helicase activity
BSK2_RS13865	COG2814	Major facilitator Superfamily
BSK2_RS13870	COG0673	inositol 2-dehydrogenase activity
BSK2_RS13875	COG2112	serine threonine protein kinase
BSK2_RS13890	COG1115	amino acid carrier protein
BSK2_RS13895	COG0217	transcriptional regulatory protein
BSK2_RS13905	COG1388	LysM domain
BSK2_RS13910	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BSK2_RS13915	COG0157	Belongs to the NadC ModD family
BSK2_RS13920	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BSK2_RS13925	COG1104	cysteine desulfurase activity
BSK2_RS13930	COG1827	regulation of RNA biosynthetic process
BSK2_RS13935	COG0077	Prephenate dehydratase
BSK2_RS13940	COG4492	Belongs to the UPF0735 family
BSK2_RS13945	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BSK2_RS13950	COG3290	protein histidine kinase activity
BSK2_RS13955	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BSK2_RS13960	COG2868	ribosomal protein
BSK2_RS13965	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BSK2_RS13970	COG1994	Peptidase M50
BSK2_RS13975	COG0739	heme binding
BSK2_RS13980	COG2894	cell division
BSK2_RS13985	COG0850	regulation of cytokinetic process
BSK2_RS13990	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BSK2_RS14000	COG1077	Cell shape determining protein MreB Mrl
BSK2_RS14005	COG2003	Belongs to the UPF0758 family
BSK2_RS14010	COG0424	maF-like protein
BSK2_RS14020	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BSK2_RS14025	COG0285	dihydrofolate synthase activity
BSK2_RS14030	COG0525	valine-tRNA ligase activity
BSK2_RS14040	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BSK2_RS14045	COG1388	LysM domain
BSK2_RS14050	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BSK2_RS14055	COG0113	porphobilinogen synthase activity
BSK2_RS14060	COG1587	Uroporphyrinogen-III synthase
BSK2_RS14065	COG0181	hydroxymethylbilane synthase activity
BSK2_RS14070	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BSK2_RS14075	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BSK2_RS14085	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BSK2_RS14090	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BSK2_RS14095	COG0470	DNA polymerase III
BSK2_RS14095	COG1067	ATP-dependent peptidase activity
BSK2_RS14100	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BSK2_RS14105	COG0544	peptidyl-prolyl cis-trans isomerase activity
BSK2_RS14110	COG1477	protein flavinylation
BSK2_RS14110	COG0457	Tetratricopeptide repeat
BSK2_RS14115	COG0066	3-isopropylmalate dehydratase activity
BSK2_RS14120	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BSK2_RS14125	COG0473	3-isopropylmalate dehydrogenase activity
BSK2_RS14130	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BSK2_RS14135	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BSK2_RS14140	COG0440	acetolactate synthase activity
BSK2_RS14145	COG0028	Belongs to the TPP enzyme family
BSK2_RS14160	COG0454	-acetyltransferase
BSK2_RS14165	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
BSK2_RS14175	COG0622	Phosphoesterase
BSK2_RS14180	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BSK2_RS14185	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BSK2_RS14190	COG5401	PFAM Sporulation and spore germination
BSK2_RS14195	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BSK2_RS14200	COG1846	Transcriptional regulator
BSK2_RS14205	COG2197	response regulator
BSK2_RS14210	COG0824	Thioesterase
BSK2_RS14215	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BSK2_RS14220	COG1053	succinate dehydrogenase
BSK2_RS14225	COG2009	succinate dehydrogenase
BSK2_RS14230	COG1719	4-vinyl reductase, 4VR
BSK2_RS14235	COG0527	aspartate kinase activity
BSK2_RS14245	COG0322	excinuclease ABC activity
BSK2_RS14250	COG3118	belongs to the thioredoxin family
BSK2_RS14260	COG3534	alpha-L-arabinofuranosidase
BSK2_RS14265	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BSK2_RS14270	COG2086	electron transfer activity
BSK2_RS14275	COG1024	Enoyl-CoA hydratase
BSK2_RS14280	COG1309	transcriptional regulator
BSK2_RS14285	COG0318	PFAM AMP-dependent synthetase and ligase
BSK2_RS14290	COG3766	membrane
BSK2_RS14295	COG1193	negative regulation of DNA recombination
BSK2_RS14300	COG1796	DNA polymerase
BSK2_RS14300	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BSK2_RS14305	COG1286	toxin biosynthetic process
BSK2_RS14310	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BSK2_RS14315	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BSK2_RS14320	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BSK2_RS14320	COG0072	phenylalanine-tRNA ligase activity
BSK2_RS14325	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BSK2_RS14335	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BSK2_RS14345	COG3835	regulator
BSK2_RS14350	COG0277	FAD linked oxidase domain protein
BSK2_RS14355	COG0247	lactate metabolic process
BSK2_RS14360	COG0346	lactoylglutathione lyase activity
BSK2_RS14370	COG1966	Carbon starvation protein
BSK2_RS14375	COG3534	alpha-L-arabinofuranosidase
BSK2_RS14380	COG0395	ABC-type sugar transport system, permease component
BSK2_RS14385	COG1175	transmembrane transport
BSK2_RS14390	COG1653	transport
BSK2_RS14395	COG0371	Dehydrogenase
BSK2_RS14400	COG0647	UMP catabolic process
BSK2_RS14405	COG0235	Class ii aldolase
BSK2_RS14410	COG1069	ribulokinase activity
BSK2_RS14415	COG2160	L-arabinose isomerase activity
BSK2_RS14420	COG3507	Belongs to the glycosyl hydrolase 43 family
BSK2_RS14425	COG1363	Peptidase, m42
BSK2_RS14435	COG3326	Membrane
BSK2_RS14440	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BSK2_RS14445	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BSK2_RS14450	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BSK2_RS14460	COG1346	cytolysis
BSK2_RS14465	COG1380	Effector of murein hydrolase LrgA
BSK2_RS14470	COG3279	Response regulator of the LytR AlgR family
BSK2_RS14475	COG3275	phosphorelay sensor kinase activity
BSK2_RS14480	COG1011	Hydrolase
BSK2_RS14485	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BSK2_RS14495	COG0398	Pfam SNARE associated Golgi protein
BSK2_RS14500	COG1484	DNA-dependent DNA replication
BSK2_RS14505	COG3611	Membrane attachment protein
BSK2_RS14510	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BSK2_RS14515	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BSK2_RS14520	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BSK2_RS14525	COG1733	regulation of RNA biosynthetic process
BSK2_RS14530	COG2814	Major facilitator Superfamily
BSK2_RS14535	COG0656	L-ascorbic acid biosynthetic process
BSK2_RS14540	COG0237	dephospho-CoA kinase activity
BSK2_RS14545	COG1971	Probably functions as a manganese efflux pump
BSK2_RS14550	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BSK2_RS14555	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BSK2_RS14555	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BSK2_RS14560	COG5002	protein histidine kinase activity
BSK2_RS14565	COG0745	RESPONSE REGULATOR receiver
BSK2_RS14570	COG0039	L-malate dehydrogenase activity
BSK2_RS14575	COG0538	isocitrate dehydrogenase activity
BSK2_RS14580	COG0372	Belongs to the citrate synthase family
BSK2_RS14585	COG2707	UPF0756 membrane protein
BSK2_RS14590	COG0628	permease
BSK2_RS14595	COG3030	protein affecting phage T7 exclusion by the F plasmid
BSK2_RS14600	COG0469	pyruvate kinase activity
BSK2_RS14605	COG0205	6-phosphofructokinase activity
BSK2_RS14610	COG0825	malonyl-CoA metabolic process
BSK2_RS14615	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BSK2_RS14620	COG0281	malic enzyme
BSK2_RS14625	COG0587	DNA-directed DNA polymerase activity
BSK2_RS14645	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BSK2_RS14655	COG4109	DRTGG domain
BSK2_RS14660	COG0730	response to heat
BSK2_RS14665	COG1473	amidohydrolase
BSK2_RS14670	COG0196	riboflavin kinase activity
BSK2_RS14675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BSK2_RS14680	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BSK2_RS14685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BSK2_RS14690	COG1126	abc transporter atp-binding protein
BSK2_RS14695	COG0765	amino acid transport
BSK2_RS14700	COG0765	amino acid transport
BSK2_RS14705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSK2_RS14710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSK2_RS14715	COG0454	-acetyltransferase
BSK2_RS14720	COG0583	DNA-binding transcription factor activity
BSK2_RS14725	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BSK2_RS14730	COG1028	Short-chain dehydrogenase reductase Sdr
BSK2_RS14740	COG0165	Argininosuccinate lyase
BSK2_RS14745	COG0137	argininosuccinate synthase activity
BSK2_RS14750	COG0521	Mo-molybdopterin cofactor biosynthetic process
BSK2_RS14755	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BSK2_RS14765	COG0827	DNA restriction-modification system
BSK2_RS14770	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BSK2_RS14775	COG3874	Sporulation protein YtfJ
BSK2_RS14785	COG1714	RDD family
BSK2_RS14790	COG0616	signal peptide processing
BSK2_RS14795	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BSK2_RS14800	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BSK2_RS14805	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BSK2_RS14815	COG0301	tRNA thio-modification
BSK2_RS14820	COG1104	cysteine desulfurase activity
BSK2_RS14825	COG1114	Component of the transport system for branched-chain amino acids
BSK2_RS14830	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BSK2_RS14835	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BSK2_RS14840	COG1309	transcriptional regulator
BSK2_RS14845	COG1956	GAF domain-containing protein
BSK2_RS14850	COG2199	diguanylate cyclase activity
BSK2_RS14850	COG2203	Gaf domain
BSK2_RS14860	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BSK2_RS14865	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BSK2_RS14875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BSK2_RS14880	COG0454	-acetyltransferase
BSK2_RS14885	COG0517	IMP dehydrogenase activity
BSK2_RS14890	COG0123	including yeast histone deacetylase and acetoin utilization protein
BSK2_RS14895	COG1360	Flagellar Motor Protein
BSK2_RS14900	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BSK2_RS14905	COG1609	Transcriptional regulator
BSK2_RS14910	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BSK2_RS14910	COG1605	Chorismate mutase
BSK2_RS14915	COG3118	belongs to the thioredoxin family
BSK2_RS14920	COG4980	gas vesicle protein
BSK2_RS14925	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BSK2_RS14930	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BSK2_RS14935	COG1674	ftsk spoiiie
BSK2_RS14940	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BSK2_RS14945	COG4848	Belongs to the UPF0354 family
BSK2_RS14950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSK2_RS14960	COG1363	Peptidase, m42
BSK2_RS14965	COG5584	Small secreted protein
BSK2_RS14970	COG0281	malic enzyme
BSK2_RS14975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSK2_RS14980	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BSK2_RS14990	COG0510	thiamine kinase activity
BSK2_RS14995	COG1523	belongs to the glycosyl hydrolase 13 family
BSK2_RS15000	COG1597	lipid kinase activity
BSK2_RS15010	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BSK2_RS15015	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BSK2_RS15020	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BSK2_RS15025	COG2252	PERMEase
BSK2_RS15030	COG4473	ABC transporter
BSK2_RS15035	COG1131	(ABC) transporter
BSK2_RS15040	COG1349	DNA-binding transcription factor activity
BSK2_RS15045	COG1187	pseudouridine synthase activity
BSK2_RS15050	COG2244	polysaccharide biosynthetic process
BSK2_RS15055	COG2081	HI0933 family
BSK2_RS15060	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BSK2_RS15070	COG5578	integral membrane protein
BSK2_RS15075	COG0673	inositol 2-dehydrogenase activity
BSK2_RS15080	COG1653	transport
BSK2_RS15085	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BSK2_RS15090	COG4209	transmembrane transport
BSK2_RS15095	COG2207	Transcriptional regulator
BSK2_RS15100	COG1653	transport
BSK2_RS15105	COG0395	ABC-type sugar transport system, permease component
BSK2_RS15110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BSK2_RS15115	COG2124	cytochrome p450
BSK2_RS15120	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BSK2_RS15130	COG0156	8-amino-7-oxononanoate synthase activity
BSK2_RS15135	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BSK2_RS15145	COG1073	alpha beta
BSK2_RS15150	COG1609	Transcriptional regulator
BSK2_RS15155	COG1653	transport
BSK2_RS15160	COG1175	transmembrane transport
BSK2_RS15165	COG0395	ABC-type sugar transport system, permease component
BSK2_RS15170	COG1486	melibiose metabolic process
BSK2_RS15175	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BSK2_RS15180	COG0495	leucyl-tRNA aminoacylation
BSK2_RS15190	COG2202	Pas domain
BSK2_RS15190	COG1366	Belongs to the anti-sigma-factor antagonist family
BSK2_RS15195	COG2814	Major facilitator Superfamily
BSK2_RS15200	COG2433	Pfam Transposase IS66
BSK2_RS15205	COG0577	efflux transmembrane transporter activity
BSK2_RS15210	COG1136	(ABC) transporter
BSK2_RS15215	COG2205	protein histidine kinase activity
BSK2_RS15220	COG0745	RESPONSE REGULATOR receiver
BSK2_RS15225	COG0577	efflux transmembrane transporter activity
BSK2_RS15230	COG1136	(ABC) transporter
BSK2_RS15245	COG1131	(ABC) transporter
BSK2_RS15250	COG1725	Transcriptional regulator
BSK2_RS15260	COG1242	4 iron, 4 sulfur cluster binding
BSK2_RS15265	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BSK2_RS15275	COG2267	carboxylic ester hydrolase activity
BSK2_RS15280	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BSK2_RS15285	COG1113	amino acid transport
BSK2_RS15290	COG0367	asparagine synthase
BSK2_RS15295	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BSK2_RS15300	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BSK2_RS15310	COG1506	peptidase
BSK2_RS15315	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BSK2_RS15320	COG1116	anion transmembrane transporter activity
BSK2_RS15325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BSK2_RS15330	COG0494	nUDIX hydrolase
BSK2_RS15335	COG4824	toxin secretion phage lysis holin
BSK2_RS15340	COG0783	Belongs to the Dps family
BSK2_RS15355	COG1854	S-ribosylhomocysteine lyase activity
BSK2_RS15360	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BSK2_RS15365	COG0288	reversible hydration of carbon dioxide
BSK2_RS15370	COG0254	rRNA binding
BSK2_RS15375	COG1271	oxidase subunit
BSK2_RS15380	COG1294	oxidase, subunit
BSK2_RS15390	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BSK2_RS15395	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BSK2_RS15395	COG1321	iron dependent repressor
BSK2_RS15400	COG1121	(ABC) transporter
BSK2_RS15405	COG0803	Belongs to the bacterial solute-binding protein 9 family
BSK2_RS15410	COG4948	Mandelate Racemase Muconate Lactonizing
BSK2_RS15415	COG0318	PFAM AMP-dependent synthetase and ligase
BSK2_RS15420	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BSK2_RS15425	COG0596	Alpha beta hydrolase
BSK2_RS15430	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BSK2_RS15435	COG1169	isochorismate synthase
BSK2_RS15445	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BSK2_RS15450	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BSK2_RS15455	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BSK2_RS15460	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BSK2_RS15465	COG0438	transferase activity, transferring glycosyl groups
BSK2_RS15475	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BSK2_RS15480	COG0438	transferase activity, transferring glycosyl groups
BSK2_RS15485	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BSK2_RS15490	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
BSK2_RS15495	COG0058	SHG alpha-glucan phosphorylase activity
BSK2_RS15500	COG0297	glycogen (starch) synthase activity
BSK2_RS15505	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BSK2_RS15510	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BSK2_RS15515	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BSK2_RS15640	COG3859	Proton-coupled thiamine transporter YuaJ
BSK2_RS15645	COG1247	-acetyltransferase
BSK2_RS15650	COG2268	Band 7 protein
BSK2_RS15655	COG1585	Membrane protein implicated in regulation of membrane protease activity
BSK2_RS15660	COG2318	DinB family
BSK2_RS15670	COG1454	alcohol dehydrogenase
BSK2_RS15675	COG1012	belongs to the aldehyde dehydrogenase family
BSK2_RS15680	COG1510	regulation of RNA biosynthetic process
BSK2_RS15690	COG0569	domain protein
BSK2_RS15695	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BSK2_RS15700	COG4682	membrane
BSK2_RS15705	COG1705	Flagellar rod assembly protein muramidase FlgJ
BSK2_RS15710	COG0477	Major facilitator Superfamily
BSK2_RS15715	COG5553	Cysteine dioxygenase type I
BSK2_RS15725	COG1968	undecaprenyl-diphosphatase activity
BSK2_RS15730	COG0628	permease
BSK2_RS15735	COG0673	inositol 2-dehydrogenase activity
BSK2_RS15740	COG4806	L-rhamnose isomerase
BSK2_RS15745	COG3254	rhamnose metabolic process
BSK2_RS15750	COG1070	Carbohydrate kinase
BSK2_RS15755	COG1349	DNA-binding transcription factor activity
BSK2_RS15760	COG3347	Dehydrogenase
BSK2_RS15760	COG1028	Short-chain dehydrogenase reductase Sdr
BSK2_RS15770	COG0840	transmembrane signaling receptor activity
BSK2_RS15775	COG0840	transmembrane signaling receptor activity
BSK2_RS15780	COG0840	transmembrane signaling receptor activity
BSK2_RS15785	COG0840	transmembrane signaling receptor activity
BSK2_RS15800	COG0432	Pfam Uncharacterised protein family UPF0047
BSK2_RS15805	COG0366	Alpha amylase catalytic
BSK2_RS15810	COG1253	flavin adenine dinucleotide binding
BSK2_RS15815	COG2738	Putative neutral zinc metallopeptidase
BSK2_RS15830	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BSK2_RS15845	COG0166	Belongs to the GPI family
BSK2_RS15850	COG1979	alcohol dehydrogenase
BSK2_RS15855	COG1979	alcohol dehydrogenase
BSK2_RS15860	COG2155	Conserved Protein
BSK2_RS15865	COG1098	S1 RNA binding domain
BSK2_RS15870	COG0436	Aminotransferase
BSK2_RS15875	COG1522	sequence-specific DNA binding
BSK2_RS15880	COG2267	carboxylic ester hydrolase activity
BSK2_RS15890	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BSK2_RS15895	COG2205	protein histidine kinase activity
BSK2_RS15905	COG5018	Exonuclease
BSK2_RS15915	COG2814	Major facilitator Superfamily
BSK2_RS15920	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BSK2_RS15925	COG3011	Protein conserved in bacteria
BSK2_RS15935	COG3290	protein histidine kinase activity
BSK2_RS15940	COG4565	transcriptional regulatory protein
BSK2_RS15945	COG1744	ABC transporter substrate-binding protein PnrA-like
BSK2_RS15950	COG3845	ABC transporter
BSK2_RS15955	COG4603	Belongs to the binding-protein-dependent transport system permease family
BSK2_RS15960	COG1079	Belongs to the binding-protein-dependent transport system permease family
BSK2_RS15965	COG3493	citrate carrier protein
BSK2_RS15975	COG2111	Na H antiporter
BSK2_RS15975	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BSK2_RS15980	COG2111	Na H antiporter
BSK2_RS15985	COG1006	Multisubunit Na H antiporter MnhC subunit
BSK2_RS15990	COG0651	ATP synthesis coupled electron transport
BSK2_RS15995	COG1863	multisubunit Na H antiporter MnhE subunit
BSK2_RS16000	COG2212	antiporter activity
BSK2_RS16005	COG1320	monovalent cation:proton antiporter activity
BSK2_RS16010	COG2050	protein possibly involved in aromatic compounds catabolism
BSK2_RS16015	COG2197	response regulator
BSK2_RS16020	COG4585	Histidine kinase
BSK2_RS16030	COG0142	geranyltranstransferase activity
BSK2_RS16045	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BSK2_RS16050	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BSK2_RS16055	COG1335	isochorismatase
BSK2_RS16060	COG5506	Protein of unknown function (DUF1694)
BSK2_RS16075	COG0628	permease
BSK2_RS16090	COG1418	mRNA catabolic process
BSK2_RS16095	COG1028	Short-chain dehydrogenase reductase Sdr
BSK2_RS16105	COG1511	domain protein
BSK2_RS16110	COG1674	ftsk spoiiie
BSK2_RS16110	COG0433	COG0433 Predicted ATPase
BSK2_RS16115	COG4499	WXG100 protein secretion system (Wss), protein YukC
BSK2_RS16120	COG5417	Belongs to the EsaB family
BSK2_RS16125	COG4842	Belongs to the WXG100 family
BSK2_RS16135	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BSK2_RS16135	COG2508	Transcriptional regulator
BSK2_RS16140	COG0686	Belongs to the AlaDH PNT family
BSK2_RS16145	COG5634	Uncharacterized conserved protein (DUF2278)
BSK2_RS16150	COG3251	PFAM MbtH domain protein
BSK2_RS16155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BSK2_RS16160	COG3433	isochorismatase activity
BSK2_RS16160	COG1535	isochorismatase
BSK2_RS16165	COG1021	2,3-dihydroxybenzoate-AMP ligase
BSK2_RS16170	COG1169	isochorismate synthase
BSK2_RS16175	COG1028	Short-chain dehydrogenase reductase Sdr
BSK2_RS16180	COG2819	hydrolase of the alpha beta superfamily
BSK2_RS16185	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BSK2_RS16190	COG1268	BioY protein
BSK2_RS16195	COG2056	Na+-H+ antiporter family
BSK2_RS16200	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BSK2_RS16205	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BSK2_RS16210	COG3584	3D domain protein
BSK2_RS16225	COG1252	NADH dehydrogenase
BSK2_RS16230	COG0492	ferredoxin-NADP+ reductase activity
BSK2_RS16240	COG0516	GMP reductase activity
BSK2_RS16250	COG2808	Putative FMN-binding domain
BSK2_RS16255	COG0456	acetyltransferase
BSK2_RS16260	COG0316	Belongs to the HesB IscA family
BSK2_RS16265	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BSK2_RS16270	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BSK2_RS16275	COG4844	belongs to the
BSK2_RS16280	COG1252	NADH dehydrogenase
BSK2_RS16285	COG4837	Protein of unknown function (DUF1462)
BSK2_RS16290	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BSK2_RS16295	COG1506	peptidase
BSK2_RS16295	COG0823	Involved in the tonB-independent uptake of proteins
BSK2_RS16295	COG4946	Tricorn protease homolog
BSK2_RS16300	COG0083	homoserine kinase activity
BSK2_RS16305	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BSK2_RS16310	COG0460	homoserine dehydrogenase
BSK2_RS16315	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BSK2_RS16320	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BSK2_RS16325	COG0647	UMP catabolic process
BSK2_RS16330	COG2445	Protein of unknown function DUF86
BSK2_RS16335	COG4470	Protein conserved in bacteria
BSK2_RS16345	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BSK2_RS16350	COG0739	heme binding
BSK2_RS16360	COG3377	Domain of unknown function (DUF1805)
BSK2_RS16365	COG0737	Belongs to the 5'-nucleotidase family
BSK2_RS16370	COG0730	response to heat
BSK2_RS16375	COG1801	Protein of unknown function DUF72
BSK2_RS16385	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BSK2_RS16390	COG2508	Transcriptional regulator
BSK2_RS16395	COG2233	PERMEase
BSK2_RS16400	COG2233	PERMEase
BSK2_RS16405	COG3195	allantoin biosynthetic process
BSK2_RS16405	COG3648	Uricase
BSK2_RS16410	COG2351	hydroxyisourate hydrolase activity
BSK2_RS16420	COG2080	2 iron, 2 sulfur cluster binding
BSK2_RS16425	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BSK2_RS16430	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BSK2_RS16435	COG2068	MobA-Related Protein
BSK2_RS16440	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BSK2_RS16445	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BSK2_RS16450	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BSK2_RS16455	COG2356	endonuclease I
BSK2_RS16460	COG3842	ATPase activity
BSK2_RS16465	COG2188	Transcriptional regulator
BSK2_RS16470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BSK2_RS16475	COG0395	ABC-type sugar transport system, permease component
BSK2_RS16480	COG1175	transmembrane transport
BSK2_RS16485	COG1653	transport
BSK2_RS16490	COG2222	sugar isomerase
BSK2_RS16495	COG0322	excinuclease ABC activity
BSK2_RS16500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSK2_RS16515	COG0346	lactoylglutathione lyase activity
BSK2_RS16520	COG0640	Transcriptional regulator
BSK2_RS16525	COG0719	Fe-S assembly protein
BSK2_RS16530	COG0822	iron-sulfur transferase activity
BSK2_RS16535	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BSK2_RS16540	COG0719	Fe-S assembly protein
BSK2_RS16545	COG0396	ATPase activity
BSK2_RS16560	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BSK2_RS16565	COG1464	Belongs to the NlpA lipoprotein family
BSK2_RS16570	COG2011	ABC-type metal ion transport system permease component
BSK2_RS16575	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BSK2_RS16585	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSK2_RS16590	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BSK2_RS16600	COG0509	glycine decarboxylation via glycine cleavage system
BSK2_RS16605	COG1393	Belongs to the ArsC family
BSK2_RS16610	COG1960	acyl-CoA dehydrogenase activity
BSK2_RS16615	COG0183	Belongs to the thiolase family
BSK2_RS16620	COG1250	3-hydroxyacyl-CoA dehydrogenase
BSK2_RS16620	COG1024	Enoyl-CoA hydratase
BSK2_RS16630	COG0506	proline dehydrogenase activity
BSK2_RS16640	COG5577	PFAM Coat F domain
BSK2_RS16645	COG1846	Transcriptional regulator
BSK2_RS16650	COG0477	Major facilitator Superfamily
BSK2_RS16655	COG1942	4-Oxalocrotonate Tautomerase
BSK2_RS16660	COG1028	Short-chain dehydrogenase reductase Sdr
BSK2_RS16675	COG1120	ATPase activity
BSK2_RS16690	COG1028	Short-chain dehydrogenase reductase Sdr
BSK2_RS16695	COG0783	Belongs to the Dps family
BSK2_RS16700	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BSK2_RS16705	COG0745	RESPONSE REGULATOR receiver
BSK2_RS16710	COG2205	protein histidine kinase activity
BSK2_RS16710	COG2770	Histidine kinase
BSK2_RS16720	COG1309	transcriptional regulator
BSK2_RS16725	COG0114	fumarate hydratase activity
BSK2_RS16735	COG0697	spore germination
BSK2_RS16740	COG0814	amino acid
BSK2_RS16750	COG2197	response regulator
BSK2_RS16755	COG4585	Histidine kinase
BSK2_RS16760	COG4758	membrane
BSK2_RS16765	COG3595	metallopeptidase activity
BSK2_RS16770	COG1842	Phage shock protein A
BSK2_RS16775	COG4758	membrane
BSK2_RS16780	COG2814	Major facilitator Superfamily
BSK2_RS16790	COG1120	ATPase activity
BSK2_RS16795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BSK2_RS16800	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BSK2_RS16805	COG1028	Short-chain dehydrogenase reductase Sdr
BSK2_RS16810	COG3386	PFAM SMP-30 Gluconolaconase
BSK2_RS16815	COG2205	protein histidine kinase activity
BSK2_RS16820	COG0745	RESPONSE REGULATOR receiver
BSK2_RS16830	COG1191	sigma factor activity
BSK2_RS16840	COG2140	Oxalate decarboxylase
BSK2_RS16850	COG0577	efflux transmembrane transporter activity
BSK2_RS16855	COG1136	(ABC) transporter
BSK2_RS16860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSK2_RS16865	COG1120	ATPase activity
BSK2_RS16870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BSK2_RS16875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BSK2_RS16880	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BSK2_RS16890	COG0531	amino acid
BSK2_RS16905	COG1988	membrane-bound metal-dependent
BSK2_RS16910	COG1368	sulfuric ester hydrolase activity
BSK2_RS16915	COG1910	domain protein
BSK2_RS16920	COG0725	ABC transporter, periplasmic molybdate-binding protein
BSK2_RS16925	COG4149	molybdate abc transporter
BSK2_RS16930	COG0656	L-ascorbic acid biosynthetic process
BSK2_RS16940	COG0025	NhaP-type Na H and K H
BSK2_RS16945	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BSK2_RS16950	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BSK2_RS16955	COG3973	AAA domain
BSK2_RS16960	COG2860	membrane
BSK2_RS16965	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BSK2_RS16970	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BSK2_RS16975	COG2217	Heavy metal translocating P-type atpase
BSK2_RS16980	COG2217	Heavy metal translocating P-type atpase
BSK2_RS16985	COG2608	mercury ion transmembrane transporter activity
BSK2_RS16990	COG1937	Protein conserved in bacteria
BSK2_RS16995	COG0673	inositol 2-dehydrogenase activity
BSK2_RS17000	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BSK2_RS17005	COG1289	transmembrane transporter activity
BSK2_RS17015	COG2076	Multidrug Resistance protein
BSK2_RS17020	COG1309	transcriptional regulator
BSK2_RS17025	COG1028	Short-chain dehydrogenase reductase Sdr
BSK2_RS17035	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BSK2_RS17040	COG0557	exoribonuclease II activity
BSK2_RS17045	COG1647	Serine aminopeptidase, S33
BSK2_RS17050	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BSK2_RS17055	COG0596	Alpha beta hydrolase
BSK2_RS17060	COG1476	TRANSCRIPTIONal
BSK2_RS17065	COG1396	sequence-specific DNA binding
BSK2_RS17070	COG1396	sequence-specific DNA binding
BSK2_RS17075	COG1733	regulation of RNA biosynthetic process
BSK2_RS17080	COG0840	transmembrane signaling receptor activity
BSK2_RS17085	COG1174	glycine betaine transport
BSK2_RS17090	COG1732	Glycine betaine
BSK2_RS17095	COG1174	glycine betaine transport
BSK2_RS17100	COG1125	glycine betaine transport
BSK2_RS17100	COG0517	IMP dehydrogenase activity
BSK2_RS17105	COG1510	regulation of RNA biosynthetic process
BSK2_RS17110	COG1174	glycine betaine transport
BSK2_RS17115	COG1732	Glycine betaine
BSK2_RS17120	COG1174	glycine betaine transport
BSK2_RS17125	COG0517	IMP dehydrogenase activity
BSK2_RS17125	COG1125	glycine betaine transport
BSK2_RS17130	COG1510	regulation of RNA biosynthetic process
BSK2_RS17135	COG2095	MarC family integral membrane protein
BSK2_RS17145	COG3064	Membrane
BSK2_RS17150	COG4640	response to antibiotic
BSK2_RS17155	COG0456	acetyltransferase
BSK2_RS17160	COG0148	phosphopyruvate hydratase activity
BSK2_RS17165	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BSK2_RS17170	COG0149	triose-phosphate isomerase activity
BSK2_RS17175	COG0126	phosphoglycerate kinase activity
BSK2_RS17180	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BSK2_RS17185	COG2390	Transcriptional regulator
BSK2_RS17190	COG2814	Major facilitator Superfamily
BSK2_RS17195	COG1609	Transcriptional regulator
BSK2_RS17200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BSK2_RS17210	COG0583	DNA-binding transcription factor activity
BSK2_RS17215	COG0697	spore germination
BSK2_RS17220	COG1113	amino acid transport
BSK2_RS17225	COG3858	chitin binding
BSK2_RS17230	COG1556	Lactate utilization protein
BSK2_RS17235	COG1139	Iron-sulfur cluster binding protein
BSK2_RS17240	COG0247	lactate metabolic process
BSK2_RS17245	COG2197	response regulator
BSK2_RS17250	COG4585	Histidine kinase
BSK2_RS17255	COG0842	Transport permease protein
BSK2_RS17260	COG1131	(ABC) transporter
BSK2_RS17265	COG0596	Alpha beta hydrolase
BSK2_RS17270	COG2208	phosphoserine phosphatase activity
BSK2_RS17275	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BSK2_RS17280	COG1874	Beta-galactosidase
BSK2_RS17285	COG3833	ABC-type maltose transport systems, permease component
BSK2_RS17290	COG1175	transmembrane transport
BSK2_RS17295	COG2182	Extracellular solute-binding protein
BSK2_RS17300	COG1609	Transcriptional regulator
BSK2_RS17305	COG2186	Transcriptional regulator
BSK2_RS17310	COG1620	l-lactate permease
BSK2_RS17315	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BSK2_RS17325	COG5039	Polysaccharide pyruvyl transferase
BSK2_RS17330	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BSK2_RS17335	COG0110	maltose O-acetyltransferase activity
BSK2_RS17340	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BSK2_RS17345	COG2244	polysaccharide biosynthetic process
BSK2_RS17350	COG1216	Glycosyl transferase, family 2
BSK2_RS17355	COG5039	Polysaccharide pyruvyl transferase
BSK2_RS17360	COG1216	Glycosyl transferase, family 2
BSK2_RS17370	COG0438	transferase activity, transferring glycosyl groups
BSK2_RS17375	COG1215	transferase activity, transferring glycosyl groups
BSK2_RS17380	COG0438	transferase activity, transferring glycosyl groups
BSK2_RS17385	COG1086	Polysaccharide biosynthesis protein
BSK2_RS17390	COG0489	protein tyrosine kinase activity
BSK2_RS17395	COG3944	biosynthesis protein
BSK2_RS17400	COG1396	sequence-specific DNA binding
BSK2_RS17405	COG2272	Belongs to the type-B carboxylesterase lipase family
BSK2_RS17415	COG3479	Phenolic acid decarboxylase
BSK2_RS17425	COG1794	racemase activity, acting on amino acids and derivatives
BSK2_RS17430	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BSK2_RS17435	COG1621	beta-fructofuranosidase activity
BSK2_RS17440	COG1621	beta-fructofuranosidase activity
BSK2_RS17445	COG0531	amino acid
BSK2_RS17450	COG1309	transcriptional regulator
BSK2_RS17455	COG2076	Multidrug Resistance protein
BSK2_RS17460	COG2076	Multidrug Resistance protein
BSK2_RS17470	COG0277	FAD linked oxidase domain protein
BSK2_RS17475	COG3621	Patatin-like phospholipase
BSK2_RS17485	COG0740	serine-type endopeptidase activity
BSK2_RS17490	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BSK2_RS17495	COG0366	Alpha amylase catalytic
BSK2_RS17500	COG1554	hydrolase, family 65, central catalytic
BSK2_RS17505	COG5521	maltodextrose utilization protein MalA
BSK2_RS17510	COG3833	ABC-type maltose transport systems, permease component
BSK2_RS17515	COG1175	transmembrane transport
BSK2_RS17520	COG2182	Extracellular solute-binding protein
BSK2_RS17525	COG0366	Alpha amylase catalytic
BSK2_RS17530	COG1609	Transcriptional regulator
BSK2_RS17535	COG1611	Belongs to the LOG family
BSK2_RS17540	COG1694	Mazg nucleotide pyrophosphohydrolase
BSK2_RS17545	COG0659	secondary active sulfate transmembrane transporter activity
BSK2_RS17550	COG0288	reversible hydration of carbon dioxide
BSK2_RS17555	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BSK2_RS17560	COG0577	efflux transmembrane transporter activity
BSK2_RS17565	COG1136	(ABC) transporter
BSK2_RS17570	COG5002	protein histidine kinase activity
BSK2_RS17575	COG0745	RESPONSE REGULATOR receiver
BSK2_RS17585	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BSK2_RS17590	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BSK2_RS17595	COG1481	regulation of sporulation
BSK2_RS17600	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BSK2_RS17605	COG1660	Displays ATPase and GTPase activities
BSK2_RS17610	COG1051	belongs to the nudix hydrolase family
BSK2_RS17615	COG0492	ferredoxin-NADP+ reductase activity
BSK2_RS17620	COG0791	NLP P60 protein
BSK2_RS17620	COG3883	PFAM NLP P60 protein
BSK2_RS17625	COG0457	Tetratricopeptide repeat
BSK2_RS17630	COG1132	(ABC) transporter
BSK2_RS17665	COG0140	phosphoribosyl-ATP diphosphatase activity
BSK2_RS17665	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BSK2_RS17670	COG0107	imidazoleglycerol-phosphate synthase activity
BSK2_RS17675	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BSK2_RS17680	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BSK2_RS17685	COG0131	Imidazoleglycerol-phosphate dehydratase
BSK2_RS17690	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BSK2_RS17695	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BSK2_RS17700	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BSK2_RS17705	COG4990	cell redox homeostasis
BSK2_RS17710	COG5297	Belongs to the glycosyl hydrolase family 6
BSK2_RS17715	COG0110	maltose O-acetyltransferase activity
BSK2_RS17720	COG0546	phosphoglycolate phosphatase activity
BSK2_RS17725	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BSK2_RS17730	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BSK2_RS17735	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BSK2_RS17740	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BSK2_RS17745	COG0363	glucosamine-6-phosphate deaminase activity
BSK2_RS17750	COG2188	Transcriptional regulator
BSK2_RS17755	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BSK2_RS17760	COG1846	Transcriptional regulator
BSK2_RS17765	COG2124	cytochrome p450
BSK2_RS17775	COG1846	Transcriptional regulator
BSK2_RS17780	COG2814	Major facilitator Superfamily
BSK2_RS17785	COG1950	PFAM Membrane protein of
BSK2_RS17790	COG1983	PspC domain protein
BSK2_RS17795	COG3595	metallopeptidase activity
BSK2_RS17810	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BSK2_RS17815	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BSK2_RS17820	COG0556	nucleotide-excision repair
BSK2_RS17825	COG4897	Protein conserved in bacteria
BSK2_RS17830	COG0574	Belongs to the PEP-utilizing enzyme family
BSK2_RS17830	COG3848	Pyruvate phosphate dikinase
BSK2_RS17835	COG1309	transcriptional regulator
BSK2_RS17840	COG2814	Major facilitator Superfamily
BSK2_RS17845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BSK2_RS17855	COG0793	Belongs to the peptidase S41A family
BSK2_RS17855	COG3409	Peptidoglycan-binding domain 1 protein
BSK2_RS17860	COG2177	Part of the ABC transporter FtsEX involved in
BSK2_RS17865	COG2884	Cell division ATP-binding protein ftsE
BSK2_RS17890	COG0494	nUDIX hydrolase
BSK2_RS17895	COG1011	Hydrolase
BSK2_RS17935	COG2010	Cytochrome c
BSK2_RS17940	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BSK2_RS17950	COG0653	protein targeting
BSK2_RS17955	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BSK2_RS17970	COG1516	flagellar protein fliS
BSK2_RS17975	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BSK2_RS17980	COG1334	flagellar protein FlaG
BSK2_RS17985	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BSK2_RS17990	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BSK2_RS17995	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BSK2_RS18005	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BSK2_RS18010	COG4786	Flagellar basal body rod
BSK2_RS18010	COG1256	bacterial-type flagellum assembly
BSK2_RS18015	COG3418	PFAM FlgN family protein
BSK2_RS18020	COG2747	anti-sigma28 factor FlgM
BSK2_RS18030	COG1040	competence protein
BSK2_RS18040	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BSK2_RS18045	COG1307	EDD domain protein, DegV family
BSK2_RS18050	COG2197	response regulator
BSK2_RS18055	COG4585	Histidine kinase
BSK2_RS18060	COG1739	Uncharacterized protein family UPF0029
BSK2_RS18065	COG1316	TRANSCRIPTIONal
BSK2_RS18070	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BSK2_RS18075	COG0438	transferase activity, transferring glycosyl groups
BSK2_RS18080	COG1215	transferase activity, transferring glycosyl groups
BSK2_RS18085	COG3206	protein involved in exopolysaccharide biosynthesis
BSK2_RS18090	COG3307	-O-antigen
BSK2_RS18095	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BSK2_RS18100	COG0438	transferase activity, transferring glycosyl groups
BSK2_RS18100	COG0297	glycogen (starch) synthase activity
BSK2_RS18105	COG2244	polysaccharide biosynthetic process
BSK2_RS18115	COG2247	cell wall binding repeat
BSK2_RS18115	COG0860	N-Acetylmuramoyl-L-alanine amidase
BSK2_RS18120	COG2247	cell wall binding repeat
BSK2_RS18120	COG2385	sporulation resulting in formation of a cellular spore
BSK2_RS18130	COG1316	TRANSCRIPTIONal
BSK2_RS18135	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BSK2_RS18140	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BSK2_RS18150	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BSK2_RS18150	COG1215	transferase activity, transferring glycosyl groups
BSK2_RS18155	COG0463	Glycosyl transferase, family 2
BSK2_RS18165	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BSK2_RS18170	COG1134	teichoic acid transport
BSK2_RS18175	COG1682	transport, permease protein
BSK2_RS18180	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BSK2_RS18185	COG0438	transferase activity, transferring glycosyl groups
BSK2_RS18190	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BSK2_RS18195	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BSK2_RS18200	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BSK2_RS18210	COG4193	domain, Protein
BSK2_RS18215	COG1482	cell wall glycoprotein biosynthetic process
BSK2_RS18220	COG0697	spore germination
BSK2_RS18225	COG0814	amino acid
BSK2_RS18235	COG2814	Major facilitator Superfamily
BSK2_RS18240	COG1316	TRANSCRIPTIONal
BSK2_RS18245	COG0561	phosphatase activity
BSK2_RS18250	COG0791	NLP P60 protein
BSK2_RS18260	COG2843	Capsule synthesis protein
BSK2_RS18270	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BSK2_RS18275	COG1609	Transcriptional regulator
BSK2_RS18280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BSK2_RS18285	COG1869	D-ribose catabolic process
BSK2_RS18290	COG1129	ABC transporter
BSK2_RS18295	COG1172	Belongs to the binding-protein-dependent transport system permease family
BSK2_RS18300	COG1879	ABC-type sugar transport system periplasmic component
BSK2_RS18305	COG3103	Sh3 type 3 domain protein
BSK2_RS18315	COG2249	NAD(P)H dehydrogenase (quinone) activity
BSK2_RS18320	COG3527	Alpha-acetolactate decarboxylase
BSK2_RS18325	COG0028	Belongs to the TPP enzyme family
BSK2_RS18330	COG0583	DNA-binding transcription factor activity
BSK2_RS18335	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BSK2_RS18350	COG5337	Spore coat protein CotH
BSK2_RS18360	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BSK2_RS18370	COG0405	Gamma-glutamyltransferase
BSK2_RS18375	COG1522	sequence-specific DNA binding
BSK2_RS18380	COG2059	Chromate
BSK2_RS18385	COG2059	Chromate
BSK2_RS18395	COG0655	NAD(P)H dehydrogenase (quinone) activity
BSK2_RS18400	COG0583	DNA-binding transcription factor activity
BSK2_RS18430	COG5444	nuclease activity
BSK2_RS18445	COG5444	nuclease activity
BSK2_RS18460	COG3878	Protein conserved in bacteria
BSK2_RS18465	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BSK2_RS18470	COG4464	protein tyrosine phosphatase activity
BSK2_RS18475	COG0489	protein tyrosine kinase activity
BSK2_RS18480	COG3944	biosynthesis protein
BSK2_RS18490	COG4715	Zinc finger, swim domain protein
BSK2_RS18495	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BSK2_RS18505	COG0561	phosphatase activity
BSK2_RS18510	COG1349	DNA-binding transcription factor activity
BSK2_RS18515	COG0629	single-stranded DNA binding
BSK2_RS18530	COG3764	Sortase (surface protein transpeptidase)
BSK2_RS18535	COG0745	RESPONSE REGULATOR receiver
BSK2_RS18535	COG2972	Histidine kinase
BSK2_RS18540	COG1970	mechanosensitive ion channel activity
BSK2_RS18545	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BSK2_RS18550	COG0457	Tetratricopeptide repeat
BSK2_RS18555	COG4786	Flagellar basal body rod
BSK2_RS18560	COG4786	Flagellar basal body rod
BSK2_RS18565	COG1077	Cell shape determining protein MreB Mrl
BSK2_RS18570	COG1609	Transcriptional regulator
BSK2_RS18580	COG1846	Transcriptional regulator
BSK2_RS18585	COG2814	Major facilitator Superfamily
BSK2_RS18590	COG3420	alginic acid biosynthetic process
BSK2_RS18595	COG1953	Uracil, thiamine, allantoin
BSK2_RS18600	COG0477	Major facilitator Superfamily
BSK2_RS18605	COG1335	isochorismatase
BSK2_RS18615	COG0004	ammonium transporteR
BSK2_RS18620	COG0347	Belongs to the P(II) protein family
BSK2_RS18625	COG0671	phosphoesterase, PA-phosphatase related
BSK2_RS18635	COG0739	heme binding
BSK2_RS18640	COG1247	-acetyltransferase
BSK2_RS18655	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BSK2_RS18660	COG0789	Transcriptional regulator
BSK2_RS18670	COG2910	NAD(P)H-binding
BSK2_RS18675	COG1959	2 iron, 2 sulfur cluster binding
BSK2_RS18680	COG0804	urea catabolic process
BSK2_RS18685	COG0832	Belongs to the urease beta subunit family
BSK2_RS18690	COG0831	urea catabolic process
BSK2_RS18705	COG3237	CsbD-like
BSK2_RS18710	COG1994	Peptidase M50
BSK2_RS18715	COG0457	Tetratricopeptide repeat
BSK2_RS18725	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BSK2_RS18730	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BSK2_RS18740	COG2304	oxidoreductase activity
BSK2_RS18750	COG2304	oxidoreductase activity
BSK2_RS18755	COG2385	sporulation resulting in formation of a cellular spore
BSK2_RS18760	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BSK2_RS18770	COG4836	Membrane
BSK2_RS18780	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BSK2_RS18785	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BSK2_RS18790	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BSK2_RS18795	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BSK2_RS18800	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BSK2_RS18805	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BSK2_RS18815	COG0356	it plays a direct role in the translocation of protons across the membrane
BSK2_RS18825	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BSK2_RS18830	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BSK2_RS18835	COG4475	Protein of unknown function (DUF436)
BSK2_RS18840	COG0698	ribose 5-phosphate isomerase
BSK2_RS18845	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BSK2_RS18850	COG1971	Probably functions as a manganese efflux pump
BSK2_RS18855	COG0009	L-threonylcarbamoyladenylate synthase
BSK2_RS18860	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BSK2_RS18880	COG2890	protein-(glutamine-N5) methyltransferase activity
BSK2_RS18885	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BSK2_RS18890	COG0346	lactoylglutathione lyase activity
BSK2_RS18895	COG0789	Transcriptional regulator
BSK2_RS18900	COG0679	Auxin Efflux Carrier
BSK2_RS18905	COG0281	malic enzyme
BSK2_RS18910	COG1435	thymidine kinase activity
BSK2_RS18920	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BSK2_RS18925	COG1494	fructose-1,6-bisphosphatase
BSK2_RS18930	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BSK2_RS18935	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BSK2_RS18940	COG0191	fructose-bisphosphate aldolase activity
BSK2_RS18945	COG2204	response regulator
BSK2_RS18950	COG4821	SIS domain
BSK2_RS18960	COG3343	RNA polymerase activity
BSK2_RS18980	COG4294	response to UV
BSK2_RS18995	COG1132	(ABC) transporter
BSK2_RS19000	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BSK2_RS19010	COG2181	nitrate reductase activity
BSK2_RS19015	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BSK2_RS19020	COG1140	nitrate reductase beta subunit
BSK2_RS19025	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BSK2_RS19030	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BSK2_RS19040	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BSK2_RS19045	COG2223	nitrite transmembrane transporter activity
BSK2_RS19050	COG0018	arginyl-trna synthetase
BSK2_RS19055	COG4506	Protein conserved in bacteria
BSK2_RS19070	COG0535	radical SAM domain protein
BSK2_RS19080	COG1131	(ABC) transporter
BSK2_RS19085	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BSK2_RS19090	COG0612	Peptidase, M16
BSK2_RS19095	COG0612	Peptidase, M16
BSK2_RS19105	COG3391	amine dehydrogenase activity
BSK2_RS19110	COG3391	amine dehydrogenase activity
BSK2_RS19120	COG0457	Tetratricopeptide repeat
BSK2_RS19135	COG0010	Belongs to the arginase family
BSK2_RS19140	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BSK2_RS19145	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BSK2_RS19160	COG1994	Peptidase M50
BSK2_RS19165	COG1942	4-Oxalocrotonate Tautomerase
BSK2_RS19170	COG1846	Transcriptional regulator
BSK2_RS19175	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BSK2_RS19180	COG0477	Major facilitator Superfamily
BSK2_RS19185	COG1959	2 iron, 2 sulfur cluster binding
BSK2_RS19190	COG3465	dGTPase activity
BSK2_RS19195	COG1078	dGTPase activity
BSK2_RS19200	COG4844	belongs to the
BSK2_RS19210	COG0697	spore germination
BSK2_RS19215	COG0095	Lipoate-protein ligase
BSK2_RS19220	COG0583	DNA-binding transcription factor activity
BSK2_RS19225	COG0280	phosphate acetyltransferase
BSK2_RS19230	COG3253	May function as heme-dependent peroxidase
BSK2_RS19235	COG1028	Short-chain dehydrogenase reductase Sdr
BSK2_RS19240	COG0436	Aminotransferase
BSK2_RS19245	COG2814	Major facilitator Superfamily
BSK2_RS19250	COG0151	Belongs to the GarS family
BSK2_RS19255	COG1028	Short-chain dehydrogenase reductase Sdr
BSK2_RS19260	COG1917	Cupin 2, conserved barrel domain protein
BSK2_RS19265	COG0077	Prephenate dehydratase
BSK2_RS19270	COG2814	Major facilitator Superfamily
BSK2_RS19275	COG0833	amino acid
BSK2_RS19280	COG4187	Peptidase family M20/M25/M40
BSK2_RS19285	COG1012	belongs to the aldehyde dehydrogenase family
BSK2_RS19290	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BSK2_RS19300	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
BSK2_RS19305	COG1091	dTDP-4-dehydrorhamnose reductase activity
BSK2_RS19310	COG1088	dTDP-glucose 4,6-dehydratase activity
BSK2_RS19315	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BSK2_RS19320	COG3980	spore coat polysaccharide biosynthesis protein
BSK2_RS19325	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
BSK2_RS19330	COG2089	acid synthase
BSK2_RS19335	COG0456	acetyltransferase
BSK2_RS19340	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BSK2_RS19345	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BSK2_RS19350	COG0463	Glycosyl transferase, family 2
BSK2_RS19365	COG2363	Small membrane protein
BSK2_RS19370	COG2233	PERMEase
BSK2_RS19380	COG1012	belongs to the aldehyde dehydrogenase family
BSK2_RS19385	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BSK2_RS19390	COG1216	Glycosyl transferase, family 2
BSK2_RS19405	COG1695	Transcriptional regulator
BSK2_RS19410	COG0351	phosphomethylpyrimidine kinase
BSK2_RS19420	COG1621	beta-fructofuranosidase activity
BSK2_RS19425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BSK2_RS19425	COG1263	PTS System
BSK2_RS19430	COG2116	formate transmembrane transporter activity
BSK2_RS19435	COG3711	transcriptional antiterminator
BSK2_RS19445	COG1404	Belongs to the peptidase S8 family
BSK2_RS19450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BSK2_RS19455	COG0778	Nitroreductase
BSK2_RS19460	COG0772	Belongs to the SEDS family
BSK2_RS19475	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BSK2_RS19480	COG1845	cytochrome c oxidase, subunit III
BSK2_RS19485	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BSK2_RS19490	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BSK2_RS19495	COG2261	transglycosylase associated protein
BSK2_RS19500	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BSK2_RS19505	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BSK2_RS19510	COG2246	polysaccharide biosynthetic process
BSK2_RS19515	COG1309	transcriptional regulator
BSK2_RS19525	COG3162	membrane
BSK2_RS19530	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BSK2_RS19535	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BSK2_RS19540	COG2837	iron assimilation
BSK2_RS19545	COG2822	iron ion transport
BSK2_RS19550	COG0672	)-iron permease
BSK2_RS19555	COG0352	thiamine-phosphate diphosphorylase activity
BSK2_RS19560	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BSK2_RS19565	COG0583	DNA-binding transcription factor activity
BSK2_RS19570	COG1380	Effector of murein hydrolase LrgA
BSK2_RS19575	COG1346	cytolysis
BSK2_RS19580	COG2814	Major facilitator Superfamily
BSK2_RS19585	COG4895	conserved protein (DUF2196)
BSK2_RS19590	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BSK2_RS19595	COG0346	lactoylglutathione lyase activity
BSK2_RS19600	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BSK2_RS19605	COG1404	Belongs to the peptidase S8 family
BSK2_RS19610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BSK2_RS19610	COG1263	PTS System
BSK2_RS19615	COG3711	transcriptional antiterminator
BSK2_RS19620	COG1442	glycosyl transferase family 8
BSK2_RS19625	COG5522	Integral membrane protein (intg_mem_TP0381)
BSK2_RS19630	COG1846	Transcriptional regulator
BSK2_RS19635	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BSK2_RS19640	COG2234	aminopeptidase activity
BSK2_RS19655	COG2814	Major facilitator Superfamily
BSK2_RS19660	COG2357	RelA SpoT domain protein
BSK2_RS19665	COG1575	Belongs to the MenA family. Type 1 subfamily
BSK2_RS19680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BSK2_RS19685	COG1696	Membrane protein involved in D-alanine export
BSK2_RS19690	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BSK2_RS19695	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BSK2_RS19700	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
BSK2_RS19705	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BSK2_RS19710	COG1486	melibiose metabolic process
BSK2_RS19715	COG1447	Phosphotransferase system cellobiose-specific component IIA
BSK2_RS19720	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BSK2_RS19725	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BSK2_RS19730	COG3711	transcriptional antiterminator
BSK2_RS19730	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BSK2_RS19740	COG2094	Belongs to the DNA glycosylase MPG family
BSK2_RS19745	COG0753	catalase activity
BSK2_RS19750	COG2814	Major facilitator Superfamily
BSK2_RS19755	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BSK2_RS19760	COG1131	(ABC) transporter
BSK2_RS19780	COG1595	DNA-templated transcription, initiation
BSK2_RS19785	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BSK2_RS19790	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BSK2_RS19795	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BSK2_RS19800	COG4988	ABC transporter
BSK2_RS19805	COG1294	oxidase, subunit
BSK2_RS19810	COG1271	oxidase subunit
BSK2_RS19815	COG3493	citrate carrier protein
BSK2_RS19820	COG0501	Belongs to the peptidase M48B family
BSK2_RS19830	COG0726	polysaccharide deacetylase
BSK2_RS19835	COG3842	ATPase activity
BSK2_RS19840	COG2508	Transcriptional regulator
BSK2_RS19845	COG1012	belongs to the aldehyde dehydrogenase family
BSK2_RS19850	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BSK2_RS19860	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BSK2_RS19870	COG4585	Histidine kinase
BSK2_RS19875	COG2197	response regulator
BSK2_RS19880	COG2195	Cleaves the N-terminal amino acid of tripeptides
BSK2_RS19890	COG4894	glucomannan catabolic process
BSK2_RS19895	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BSK2_RS19900	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BSK2_RS19905	COG1028	Short-chain dehydrogenase reductase Sdr
BSK2_RS19910	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BSK2_RS19915	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BSK2_RS19920	COG2610	gluconate transmembrane transporter activity
BSK2_RS19925	COG0500	methyltransferase
BSK2_RS19930	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BSK2_RS19945	COG0753	catalase activity
BSK2_RS19945	COG0693	protein deglycase activity
BSK2_RS19950	COG2851	Citrate transporter
BSK2_RS19955	COG2273	Hydrolase Family 16
BSK2_RS19960	COG3711	transcriptional antiterminator
BSK2_RS19970	COG2270	Major facilitator Superfamily
BSK2_RS19975	COG0513	Belongs to the DEAD box helicase family
BSK2_RS19980	COG2755	lipolytic protein G-D-S-L family
BSK2_RS19980	COG3401	FG-GAP repeat protein
BSK2_RS20035	COG0589	response to stress
BSK2_RS20040	COG2723	6-phospho-beta-galactosidase activity
BSK2_RS20045	COG1263	PTS System
BSK2_RS20045	COG2190	(PTS) system
BSK2_RS20045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BSK2_RS20050	COG5444	nuclease activity
BSK2_RS20060	COG5444	nuclease activity
BSK2_RS20075	COG3507	Belongs to the glycosyl hydrolase 43 family
BSK2_RS20090	COG2986	histidine ammonia-lyase
BSK2_RS20095	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BSK2_RS20100	COG1228	amidohydrolase
BSK2_RS20105	COG0010	Belongs to the arginase family
BSK2_RS20110	COG0833	amino acid
BSK2_RS20115	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BSK2_RS20120	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BSK2_RS20125	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BSK2_RS20130	COG2390	Transcriptional regulator
BSK2_RS20140	COG3192	ethanolamine utilization protein
BSK2_RS20145	COG2079	MmgE PrpD family protein
BSK2_RS20150	COG1473	amidohydrolase
BSK2_RS20155	COG1126	abc transporter atp-binding protein
BSK2_RS20160	COG0765	amino acid transport
BSK2_RS20165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSK2_RS20170	COG0456	acetyltransferase
BSK2_RS20175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BSK2_RS20180	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BSK2_RS20185	COG0561	phosphatase activity
BSK2_RS20215	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BSK2_RS20220	COG5294	Protein conserved in bacteria
BSK2_RS20225	COG0577	efflux transmembrane transporter activity
BSK2_RS20230	COG1136	(ABC) transporter
BSK2_RS20235	COG2205	protein histidine kinase activity
BSK2_RS20240	COG0745	RESPONSE REGULATOR receiver
BSK2_RS20245	COG0191	fructose-bisphosphate aldolase activity
BSK2_RS20250	COG1082	Xylose isomerase domain protein TIM barrel
BSK2_RS20255	COG1082	Xylose isomerase domain protein TIM barrel
BSK2_RS20260	COG0673	inositol 2-dehydrogenase activity
BSK2_RS20265	COG2814	Major facilitator Superfamily
BSK2_RS20270	COG1082	Xylose isomerase domain protein TIM barrel
BSK2_RS20275	COG3962	Belongs to the TPP enzyme family
BSK2_RS20280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BSK2_RS20290	COG1012	belongs to the aldehyde dehydrogenase family
BSK2_RS20295	COG1349	DNA-binding transcription factor activity
BSK2_RS20300	COG0667	Aldo Keto reductase
BSK2_RS20315	COG2814	Major facilitator Superfamily
BSK2_RS20320	COG0326	Molecular chaperone. Has ATPase activity
BSK2_RS20330	COG1028	Short-chain dehydrogenase reductase Sdr
BSK2_RS20335	COG1309	transcriptional regulator
BSK2_RS20340	COG1012	belongs to the aldehyde dehydrogenase family
BSK2_RS20350	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BSK2_RS20360	COG1714	RDD family
BSK2_RS20365	COG2311	Membrane
BSK2_RS20370	COG1917	Cupin 2, conserved barrel domain protein
BSK2_RS20375	COG1309	transcriptional regulator
BSK2_RS20380	COG1028	Short-chain dehydrogenase reductase Sdr
BSK2_RS20385	COG1846	Transcriptional regulator
BSK2_RS20390	COG1380	Effector of murein hydrolase LrgA
BSK2_RS20395	COG1346	cytolysis
BSK2_RS20400	COG5039	Polysaccharide pyruvyl transferase
BSK2_RS20405	COG1929	Belongs to the glycerate kinase type-1 family
BSK2_RS20410	COG1802	Transcriptional regulator
BSK2_RS20415	COG1070	Carbohydrate kinase
BSK2_RS20420	COG2610	gluconate transmembrane transporter activity
BSK2_RS20425	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BSK2_RS20430	COG0450	alkyl hydroperoxide reductase
BSK2_RS20435	COG3634	alkyl hydroperoxide reductase activity
BSK2_RS20440	COG2723	6-phospho-beta-galactosidase activity
BSK2_RS20445	COG2190	(PTS) system
BSK2_RS20450	COG2190	(PTS) system
BSK2_RS20450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BSK2_RS20450	COG1263	PTS System
BSK2_RS20455	COG2188	Transcriptional regulator
BSK2_RS20465	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
BSK2_RS20470	COG0210	DNA helicase
BSK2_RS20490	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BSK2_RS20505	COG1063	alcohol dehydrogenase
BSK2_RS20525	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
BSK2_RS20530	COG0456	acetyltransferase
BSK2_RS20535	COG0457	Tetratricopeptide repeat
BSK2_RS20545	COG0010	Belongs to the arginase family
BSK2_RS20550	COG0833	amino acid
BSK2_RS20555	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BSK2_RS20560	COG3829	transcription factor binding
BSK2_RS20565	COG5002	protein histidine kinase activity
BSK2_RS20570	COG0745	RESPONSE REGULATOR receiver
BSK2_RS20585	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BSK2_RS20590	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BSK2_RS20595	COG4853	Protein conserved in bacteria
BSK2_RS20600	COG4863	YycH protein
BSK2_RS20605	COG5002	protein histidine kinase activity
BSK2_RS20610	COG0745	RESPONSE REGULATOR receiver
BSK2_RS20640	COG0346	lactoylglutathione lyase activity
BSK2_RS20645	COG0305	Participates in initiation and elongation during chromosome replication
BSK2_RS20660	COG3093	addiction module antidote protein HigA
BSK2_RS20665	COG2807	transmembrane transport
BSK2_RS20670	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BSK2_RS20675	COG0359	binds to the 23S rRNA
BSK2_RS20680	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BSK2_RS20685	COG4241	membrane
BSK2_RS20695	COG5577	PFAM Coat F domain
BSK2_RS20700	COG1733	regulation of RNA biosynthetic process
BSK2_RS20705	COG1227	inorganic diphosphatase activity
BSK2_RS20720	COG2271	Major facilitator Superfamily
BSK2_RS20725	COG0789	Transcriptional regulator
BSK2_RS20725	COG4978	Transcriptional regulator
BSK2_RS20735	COG4319	ketosteroid isomerase
BSK2_RS20740	COG1357	PFAM Pentapeptide repeats (8 copies)
BSK2_RS20745	COG2814	Major facilitator Superfamily
BSK2_RS20750	COG0583	DNA-binding transcription factor activity
BSK2_RS20755	COG2153	protein acetylation
BSK2_RS20765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSK2_RS20770	COG1846	Transcriptional regulator
BSK2_RS20775	COG2153	protein acetylation
BSK2_RS20780	COG2364	Membrane
BSK2_RS20785	COG0456	acetyltransferase
BSK2_RS20790	COG2315	Protein conserved in bacteria
BSK2_RS20795	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BSK2_RS20805	COG2814	Major facilitator Superfamily
BSK2_RS20810	COG1331	Highly conserved protein containing a thioredoxin domain
BSK2_RS20815	COG0789	Transcriptional regulator
BSK2_RS20820	COG0697	spore germination
BSK2_RS20825	COG1331	Highly conserved protein containing a thioredoxin domain
BSK2_RS20830	COG1266	CAAX protease self-immunity
BSK2_RS20835	COG0477	Major facilitator Superfamily
BSK2_RS20835	COG2814	Major facilitator Superfamily
BSK2_RS20840	COG0110	maltose O-acetyltransferase activity
BSK2_RS20845	COG0346	lactoylglutathione lyase activity
BSK2_RS20850	COG1609	Transcriptional regulator
BSK2_RS20855	COG0708	Exodeoxyribonuclease III
BSK2_RS20860	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BSK2_RS20865	COG0629	single-stranded DNA binding
BSK2_RS20870	COG0360	Binds together with S18 to 16S ribosomal RNA
BSK2_RS20875	COG0012	GTP binding
BSK2_RS20880	COG0243	molybdopterin cofactor binding
BSK2_RS20885	COG4481	Protein conserved in bacteria
BSK2_RS20890	COG3949	Membrane
BSK2_RS20900	COG1475	DNA binding
BSK2_RS20905	COG1192	Involved in chromosome partitioning
BSK2_RS20915	COG1475	DNA binding
BSK2_RS20920	COG0357	Ribosomal RNA small subunit methyltransferase G
BSK2_RS20925	COG0445	tRNA wobble uridine modification
BSK2_RS20930	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BSK2_RS20935	COG1847	R3H domain protein
BSK2_RS20940	COG0706	membrane insertase activity
BSK2_RS20945	COG0594	ribonuclease P activity