locus-tag	class	description
AW03_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AW03_RS00010	COG0592	DNA-directed DNA polymerase activity
AW03_RS00015	COG2501	S4 domain
AW03_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AW03_RS00030	COG0187	DNA topoisomerase II activity
AW03_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AW03_RS00070	COG0516	GMP reductase activity
AW03_RS00070	COG0517	IMP dehydrogenase activity
AW03_RS00075	COG1686	Belongs to the peptidase S11 family
AW03_RS00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
AW03_RS00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AW03_RS00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AW03_RS00100	COG1428	Deoxynucleoside kinase
AW03_RS00105	COG1428	Deoxynucleoside kinase
AW03_RS00110	COG1388	LysM domain
AW03_RS00110	COG3858	chitin binding
AW03_RS00115	COG1335	isochorismatase
AW03_RS00120	COG0590	tRNA wobble adenosine to inosine editing
AW03_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AW03_RS00130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AW03_RS00135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AW03_RS00180	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
AW03_RS00185	COG3853	Toxic anion resistance protein (TelA)
AW03_RS00190	COG1982	Orn Lys Arg decarboxylase major
AW03_RS00195	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AW03_RS00200	COG3870	Protein conserved in bacteria
AW03_RS00205	COG1728	Protein conserved in bacteria
AW03_RS00210	COG0470	DNA polymerase III
AW03_RS00215	COG1774	PSP1 C-terminal conserved region
AW03_RS00220	COG4467	Involved in initiation control of chromosome replication
AW03_RS00225	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AW03_RS00230	COG2827	Endonuclease containing a URI domain
AW03_RS00235	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AW03_RS00240	COG2002	toxin-antitoxin pair type II binding
AW03_RS00245	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AW03_RS00245	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AW03_RS00250	COG0084	hydrolase, TatD family'
AW03_RS00255	COG3583	domain protein
AW03_RS00255	COG3584	3D domain protein
AW03_RS00260	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AW03_RS00265	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AW03_RS00275	COG4466	Protein conserved in bacteria
AW03_RS00285	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AW03_RS00290	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AW03_RS00295	COG0251	oxidation-reduction process
AW03_RS00300	COG2088	sporulation resulting in formation of a cellular spore
AW03_RS00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AW03_RS00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AW03_RS00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AW03_RS00325	COG0193	aminoacyl-tRNA hydrolase activity
AW03_RS00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AW03_RS00340	COG2002	toxin-antitoxin pair type II binding
AW03_RS00345	COG2244	polysaccharide biosynthetic process
AW03_RS00350	COG3956	TIGRFAM MazG family protein
AW03_RS00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AW03_RS00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AW03_RS00375	COG1098	S1 RNA binding domain
AW03_RS00390	COG2208	phosphoserine phosphatase activity
AW03_RS00395	COG2304	oxidoreductase activity
AW03_RS00400	COG0515	serine threonine protein kinase
AW03_RS00405	COG0037	tRNA processing
AW03_RS00410	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AW03_RS00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AW03_RS00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AW03_RS00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AW03_RS00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AW03_RS00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AW03_RS00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AW03_RS00445	COG0512	Glutamine amidotransferase of anthranilate synthase
AW03_RS00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AW03_RS00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AW03_RS00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AW03_RS00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AW03_RS00470	COG1396	sequence-specific DNA binding
AW03_RS00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AW03_RS00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AW03_RS00505	COG4463	regulation of RNA biosynthetic process
AW03_RS00510	COG3880	PFAM UvrB UvrC protein
AW03_RS00515	COG3869	Catalyzes the specific phosphorylation of arginine residues in
AW03_RS00520	COG0542	response to heat
AW03_RS00525	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AW03_RS00530	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
AW03_RS00535	COG4956	integral membrane protein (PIN domain superfamily)
AW03_RS00540	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AW03_RS00545	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AW03_RS00550	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AW03_RS00560	COG1045	serine acetyltransferase
AW03_RS00565	COG0215	cysteine-tRNA ligase activity
AW03_RS00570	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AW03_RS00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AW03_RS00580	COG3688	RNA-binding protein containing a PIN domain
AW03_RS00585	COG1595	DNA-templated transcription, initiation
AW03_RS00595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AW03_RS00600	COG0250	Participates in transcription elongation, termination and antitermination
AW03_RS00610	COG0081	regulation of translation
AW03_RS00615	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AW03_RS00625	COG2813	Specifically methylates the guanine in position
AW03_RS00630	COG0085	RNA polymerase activity
AW03_RS00635	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AW03_RS00640	COG1358	cellular component organization or biogenesis
AW03_RS00645	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AW03_RS00650	COG0049	tRNA binding
AW03_RS00655	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AW03_RS00660	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AW03_RS00665	COG0596	Alpha beta hydrolase
AW03_RS00675	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AW03_RS00680	COG0088	Forms part of the polypeptide exit tunnel
AW03_RS00690	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AW03_RS00710	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AW03_RS00720	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AW03_RS00725	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AW03_RS00735	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AW03_RS00745	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AW03_RS00750	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AW03_RS00755	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AW03_RS00760	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AW03_RS00770	COG0200	Binds to the 23S rRNA
AW03_RS00775	COG0201	protein transport
AW03_RS00780	COG0563	adenylate kinase activity
AW03_RS00785	COG0024	Methionine aminopeptidase
AW03_RS00790	COG2163	COG2163 Ribosomal protein L14E L6E L27E
AW03_RS00800	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AW03_RS00805	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AW03_RS00810	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AW03_RS00815	COG0202	RNA polymerase activity
AW03_RS00820	COG0203	ribosomal protein L17
AW03_RS00825	COG1122	ATPase activity
AW03_RS00830	COG1122	ATPase activity
AW03_RS00835	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AW03_RS00840	COG0101	tRNA pseudouridine synthase activity
AW03_RS00845	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AW03_RS00850	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AW03_RS00855	COG2226	methyltransferase
AW03_RS00865	COG0860	N-Acetylmuramoyl-L-alanine amidase
AW03_RS00870	COG0489	protein tyrosine kinase activity
AW03_RS00880	COG2194	sulfuric ester hydrolase activity
AW03_RS00885	COG0726	polysaccharide deacetylase
AW03_RS00910	COG0659	secondary active sulfate transmembrane transporter activity
AW03_RS00915	COG0385	Bile acid
AW03_RS00920	COG2819	hydrolase of the alpha beta superfamily
AW03_RS00925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW03_RS00930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW03_RS00935	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW03_RS00940	COG2207	Transcriptional regulator
AW03_RS00940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW03_RS00945	COG3876	Protein conserved in bacteria
AW03_RS00950	COG1472	Belongs to the glycosyl hydrolase 3 family
AW03_RS00955	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AW03_RS00960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW03_RS00960	COG1263	PTS System
AW03_RS00965	COG1737	Transcriptional regulator
AW03_RS00970	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AW03_RS00975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW03_RS00980	COG1683	Conserved Protein
AW03_RS01010	COG1595	DNA-templated transcription, initiation
AW03_RS01015	COG5662	AntiSigma factor
AW03_RS01020	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AW03_RS01025	COG4856	YbbR-like protein
AW03_RS01030	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AW03_RS01035	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AW03_RS01045	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AW03_RS01050	COG3002	Belongs to the UPF0753 family
AW03_RS01055	COG0288	reversible hydration of carbon dioxide
AW03_RS01065	COG5609	conserved protein (DUF2294)
AW03_RS01075	COG0640	Transcriptional regulator
AW03_RS01080	COG2814	Major facilitator Superfamily
AW03_RS01095	COG0596	Alpha beta hydrolase
AW03_RS01100	COG0745	RESPONSE REGULATOR receiver
AW03_RS01105	COG0642	Histidine kinase
AW03_RS01115	COG0515	serine threonine protein kinase
AW03_RS01130	COG1113	amino acid transport
AW03_RS01145	COG2602	Beta-lactamase
AW03_RS01150	COG2124	cytochrome p450
AW03_RS01160	COG0531	amino acid
AW03_RS01165	COG0584	glycerophosphoryl diester phosphodiesterase
AW03_RS01170	COG2271	Major facilitator Superfamily
AW03_RS01180	COG0456	acetyltransferase
AW03_RS01180	COG1846	Transcriptional regulator
AW03_RS01185	COG2271	Major facilitator Superfamily
AW03_RS01195	COG0697	spore germination
AW03_RS01200	COG2207	Transcriptional regulator
AW03_RS01200	COG1917	Cupin 2, conserved barrel domain protein
AW03_RS01205	COG1397	ADP-ribosylglycohydrolase
AW03_RS01220	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AW03_RS01225	COG3591	Belongs to the peptidase S1B family
AW03_RS01235	COG0596	Alpha beta hydrolase
AW03_RS01240	COG1183	phosphatidylcholine synthase activity
AW03_RS01245	COG0586	Pfam SNARE associated Golgi protein
AW03_RS01250	COG0688	phosphatidylethanolamine metabolic process
AW03_RS01260	COG2312	Erythromycin esterase
AW03_RS01265	COG1054	Belongs to the UPF0176 family
AW03_RS01270	COG1301	dicarboxylic acid transport
AW03_RS01275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW03_RS01275	COG2190	(PTS) system
AW03_RS01275	COG1263	PTS System
AW03_RS01280	COG0363	glucosamine-6-phosphate deaminase activity
AW03_RS01285	COG2188	Transcriptional regulator
AW03_RS01295	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AW03_RS01300	COG0833	amino acid
AW03_RS01305	COG2040	homocysteine
AW03_RS01315	COG1115	amino acid carrier protein
AW03_RS01320	COG2066	Belongs to the glutaminase family
AW03_RS01325	COG4191	Histidine kinase
AW03_RS01330	COG0784	Response regulator, receiver
AW03_RS01335	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AW03_RS01340	COG1012	belongs to the aldehyde dehydrogenase family
AW03_RS01345	COG2271	Major facilitator Superfamily
AW03_RS01350	COG4948	Mandelate Racemase Muconate Lactonizing
AW03_RS01355	COG2186	Transcriptional regulator
AW03_RS01360	COG2721	sulfolactate sulfo-lyase activity
AW03_RS01365	COG3173	Aminoglycoside phosphotransferase
AW03_RS01375	COG0697	spore germination
AW03_RS01380	COG0745	RESPONSE REGULATOR receiver
AW03_RS01385	COG2205	protein histidine kinase activity
AW03_RS01390	COG1131	(ABC) transporter
AW03_RS01410	COG3773	Cell wall hydrolase
AW03_RS01415	COG2304	oxidoreductase activity
AW03_RS01425	COG3540	Alkaline phosphatase
AW03_RS01430	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AW03_RS01435	COG0805	protein transport
AW03_RS01440	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AW03_RS01445	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AW03_RS01450	COG0477	Major facilitator Superfamily
AW03_RS01455	COG1309	transcriptional regulator
AW03_RS01460	COG0252	asparaginase activity
AW03_RS01465	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AW03_RS01470	COG1714	RDD family
AW03_RS01475	COG1405	negative regulation of cell septum assembly
AW03_RS01475	COG3012	SEC-C Motif Domain Protein
AW03_RS01480	COG3290	protein histidine kinase activity
AW03_RS01485	COG3279	Response regulator of the LytR AlgR family
AW03_RS01490	COG4555	ABC transporter
AW03_RS01495	COG1668	transmembrane transport
AW03_RS01500	COG0667	Aldo Keto reductase
AW03_RS01510	COG1595	DNA-templated transcription, initiation
AW03_RS01515	COG1595	DNA-templated transcription, initiation
AW03_RS01520	COG1876	peptidase activity
AW03_RS01525	COG0457	Tetratricopeptide repeat
AW03_RS01530	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_RS01535	COG0366	Alpha amylase catalytic
AW03_RS01540	COG0803	Belongs to the bacterial solute-binding protein 9 family
AW03_RS01545	COG1121	(ABC) transporter
AW03_RS01550	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AW03_RS01555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AW03_RS01560	COG2310	stress, protein
AW03_RS01565	COG2310	stress, protein
AW03_RS01570	COG2310	stress, protein
AW03_RS01575	COG0861	Integral membrane protein TerC family
AW03_RS01585	COG3853	Toxic anion resistance protein (TelA)
AW03_RS01590	COG0477	Major facilitator Superfamily
AW03_RS01595	COG2814	Major facilitator Superfamily
AW03_RS01600	COG0640	Transcriptional regulator
AW03_RS01605	COG0517	IMP dehydrogenase activity
AW03_RS01605	COG4175	Glycine betaine
AW03_RS01610	COG4176	ABC-type proline glycine betaine transport system permease component
AW03_RS01615	COG2113	Glycine betaine
AW03_RS01620	COG1473	amidohydrolase
AW03_RS01625	COG1288	antiporter activity
AW03_RS01640	COG0366	Alpha amylase catalytic
AW03_RS01645	COG0039	L-malate dehydrogenase activity
AW03_RS01650	COG1620	l-lactate permease
AW03_RS01655	COG2814	Major facilitator Superfamily
AW03_RS01660	COG1846	Transcriptional regulator
AW03_RS01665	COG1280	lysine exporter protein (LysE YggA)
AW03_RS01670	COG3403	YqcI/YcgG family
AW03_RS01675	COG1113	amino acid transport
AW03_RS01680	COG3665	Urea carboxylase-associated protein
AW03_RS01685	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AW03_RS01690	COG1660	Displays ATPase and GTPase activities
AW03_RS01695	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AW03_RS01700	COG2226	methyltransferase
AW03_RS01705	COG0583	DNA-binding transcription factor activity
AW03_RS01710	COG3458	cephalosporin-C deacetylase activity
AW03_RS01715	COG3541	Predicted nucleotidyltransferase
AW03_RS01720	COG0506	proline dehydrogenase activity
AW03_RS01725	COG1012	belongs to the aldehyde dehydrogenase family
AW03_RS01730	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AW03_RS01735	COG2508	Transcriptional regulator
AW03_RS01740	COG3689	TIGRFAM TIGR03943 family protein
AW03_RS01745	COG0701	Predicted permease
AW03_RS01750	COG2267	carboxylic ester hydrolase activity
AW03_RS01755	COG0492	ferredoxin-NADP+ reductase activity
AW03_RS01760	COG1587	Uroporphyrinogen-III synthase
AW03_RS01760	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AW03_RS01765	COG2146	nitrite reductase [NAD(P)H] activity
AW03_RS01770	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AW03_RS01775	COG0243	molybdopterin cofactor binding
AW03_RS01780	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AW03_RS01785	COG2223	nitrite transmembrane transporter activity
AW03_RS01790	COG1469	GTP cyclohydrolase I activity
AW03_RS01795	COG1376	ErfK ybiS ycfS ynhG family protein
AW03_RS01805	COG0523	cobalamin synthesis protein
AW03_RS01810	COG0765	amino acid transport
AW03_RS01815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW03_RS01825	COG1714	RDD family
AW03_RS01835	COG2723	6-phospho-beta-galactosidase activity
AW03_RS01845	COG3209	COG3209 Rhs family protein
AW03_RS01850	COG0840	transmembrane signaling receptor activity
AW03_RS01850	COG3290	protein histidine kinase activity
AW03_RS01855	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AW03_RS01860	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AW03_RS01865	COG1733	regulation of RNA biosynthetic process
AW03_RS01875	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW03_RS01880	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW03_RS01885	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW03_RS01890	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AW03_RS01895	COG2814	Major facilitator Superfamily
AW03_RS01905	COG0697	spore germination
AW03_RS01910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW03_RS01920	COG2364	Membrane
AW03_RS01925	COG1126	abc transporter atp-binding protein
AW03_RS01930	COG0765	amino acid transport
AW03_RS01935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW03_RS01940	COG0583	DNA-binding transcription factor activity
AW03_RS01945	COG0163	prenyltransferase activity
AW03_RS01950	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AW03_RS01965	COG0596	Alpha beta hydrolase
AW03_RS01970	COG3104	oligopeptide transport
AW03_RS01975	COG5434	Belongs to the glycosyl hydrolase 28 family
AW03_RS01985	COG0697	spore germination
AW03_RS01995	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AW03_RS02000	COG1136	(ABC) transporter
AW03_RS02005	COG0577	efflux transmembrane transporter activity
AW03_RS02010	COG0745	RESPONSE REGULATOR receiver
AW03_RS02015	COG3850	Histidine kinase
AW03_RS02015	COG5002	protein histidine kinase activity
AW03_RS02020	COG0457	Tetratricopeptide repeat
AW03_RS02040	COG0527	aspartate kinase activity
AW03_RS02045	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW03_RS02050	COG4605	iron ion homeostasis
AW03_RS02055	COG4604	ABC transporter, ATP-binding protein
AW03_RS02060	COG4607	ABC-type enterochelin transport system periplasmic component
AW03_RS02065	COG2814	Major facilitator Superfamily
AW03_RS02070	COG1309	transcriptional regulator
AW03_RS02075	COG0778	Nitroreductase
AW03_RS02080	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AW03_RS02085	COG0640	Transcriptional regulator
AW03_RS02090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW03_RS02095	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AW03_RS02100	COG1012	belongs to the aldehyde dehydrogenase family
AW03_RS02105	COG4975	Glucose uptake
AW03_RS02110	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_RS02115	COG4549	nuclear export factor GLE1
AW03_RS02120	COG2372	response to copper ion
AW03_RS02120	COG1276	copper resistance
AW03_RS02125	COG1349	DNA-binding transcription factor activity
AW03_RS02135	COG2213	PTS system mannitol-specific
AW03_RS02140	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW03_RS02145	COG0246	Mannitol dehydrogenase
AW03_RS02150	COG0473	3-isopropylmalate dehydrogenase activity
AW03_RS02155	COG0681	Belongs to the peptidase S26 family
AW03_RS02160	COG0412	Dienelactone hydrolase
AW03_RS02165	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AW03_RS02175	COG0561	phosphatase activity
AW03_RS02180	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AW03_RS02185	COG1914	H( )-stimulated, divalent metal cation uptake system
AW03_RS02190	COG4336	lyase activity
AW03_RS02195	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AW03_RS02200	COG1984	allophanate hydrolase subunit 2
AW03_RS02205	COG1414	Transcriptional regulator
AW03_RS02210	COG2755	lipolytic protein G-D-S-L family
AW03_RS02220	COG2329	Antibiotic biosynthesis monooxygenase
AW03_RS02225	COG0768	penicillin binding
AW03_RS02230	COG4989	oxidoreductase activity
AW03_RS02235	COG3711	transcriptional antiterminator
AW03_RS02240	COG0318	PFAM AMP-dependent synthetase and ligase
AW03_RS02245	COG2226	methyltransferase
AW03_RS02250	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_RS02255	COG1917	Cupin 2, conserved barrel domain protein
AW03_RS02260	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW03_RS02265	COG3871	stress protein (general stress protein 26)
AW03_RS02275	COG2814	Major facilitator Superfamily
AW03_RS02280	COG1522	sequence-specific DNA binding
AW03_RS02285	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AW03_RS02285	COG0551	DNA topoisomerase type I activity
AW03_RS02290	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AW03_RS02295	COG3706	GGDEF domain
AW03_RS02300	COG5298	Protein conserved in bacteria
AW03_RS02305	COG1215	transferase activity, transferring glycosyl groups
AW03_RS02315	COG0531	amino acid
AW03_RS02320	COG0494	nUDIX hydrolase
AW03_RS02325	COG0028	Belongs to the TPP enzyme family
AW03_RS02340	COG1914	H( )-stimulated, divalent metal cation uptake system
AW03_RS02345	COG2261	transglycosylase associated protein
AW03_RS02350	COG4876	unkown
AW03_RS02355	COG2217	Heavy metal translocating P-type atpase
AW03_RS02360	COG3729	General stress protein
AW03_RS02365	COG0662	Cupin 2, conserved barrel domain protein
AW03_RS02370	COG2329	Antibiotic biosynthesis monooxygenase
AW03_RS02375	COG3546	catalase activity
AW03_RS02380	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AW03_RS02385	COG3290	protein histidine kinase activity
AW03_RS02390	COG4565	transcriptional regulatory protein
AW03_RS02395	COG1301	dicarboxylic acid transport
AW03_RS02400	COG0628	permease
AW03_RS02410	COG1131	(ABC) transporter
AW03_RS02415	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AW03_RS02425	COG1960	acyl-CoA dehydrogenase activity
AW03_RS02440	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AW03_RS02445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW03_RS02450	COG1181	Belongs to the D-alanine--D-alanine ligase family
AW03_RS02455	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AW03_RS02460	COG0513	Belongs to the DEAD box helicase family
AW03_RS02465	COG3402	PFAM membrane-flanked domain
AW03_RS02470	COG3428	Bacterial PH domain
AW03_RS02475	COG0705	Rhomboid family
AW03_RS02480	COG0736	holo-[acyl-carrier-protein] synthase activity
AW03_RS02485	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AW03_RS02490	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AW03_RS02495	COG0864	Transcriptional regulator
AW03_RS02500	COG2337	Toxic component of a toxin-antitoxin (TA) module
AW03_RS02505	COG1366	Belongs to the anti-sigma-factor antagonist family
AW03_RS02510	COG1366	Belongs to the anti-sigma-factor antagonist family
AW03_RS02515	COG2172	sigma factor antagonist activity
AW03_RS02520	COG2208	phosphoserine phosphatase activity
AW03_RS02525	COG1366	Belongs to the anti-sigma-factor antagonist family
AW03_RS02530	COG2172	sigma factor antagonist activity
AW03_RS02535	COG1191	sigma factor activity
AW03_RS02540	COG2208	phosphoserine phosphatase activity
AW03_RS02555	COG1673	EVE domain
AW03_RS02560	COG1846	Transcriptional regulator
AW03_RS02565	COG2183	response to ionizing radiation
AW03_RS02575	COG3091	SprT-like family
AW03_RS02620	COG0515	serine threonine protein kinase
AW03_RS02625	COG0515	serine threonine protein kinase
AW03_RS02630	COG1132	(ABC) transporter
AW03_RS02645	COG1476	TRANSCRIPTIONal
AW03_RS02655	COG3239	Fatty acid desaturase
AW03_RS02660	COG1278	Cold shock
AW03_RS02665	COG1329	Transcriptional regulator
AW03_RS02670	COG2207	Transcriptional regulator
AW03_RS02670	COG1917	Cupin 2, conserved barrel domain protein
AW03_RS02675	COG0697	spore germination
AW03_RS02680	COG2207	Transcriptional regulator
AW03_RS02680	COG3708	Transcriptional regulator
AW03_RS02685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW03_RS02690	COG0477	Major facilitator Superfamily
AW03_RS02700	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
AW03_RS02710	COG0697	spore germination
AW03_RS02715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW03_RS02720	COG2030	dehydratase
AW03_RS02725	COG3545	Serine hydrolase
AW03_RS02730	COG1733	regulation of RNA biosynthetic process
AW03_RS02735	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW03_RS02740	COG1733	regulation of RNA biosynthetic process
AW03_RS02745	COG2249	NAD(P)H dehydrogenase (quinone) activity
AW03_RS02750	COG2814	Major facilitator Superfamily
AW03_RS02755	COG1309	transcriptional regulator
AW03_RS02765	COG0640	Transcriptional regulator
AW03_RS02770	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AW03_RS02780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW03_RS02785	COG1316	TRANSCRIPTIONal
AW03_RS02800	COG5002	protein histidine kinase activity
AW03_RS02805	COG0745	RESPONSE REGULATOR receiver
AW03_RS02810	COG0697	spore germination
AW03_RS02815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW03_RS02820	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AW03_RS02825	COG0640	Transcriptional regulator
AW03_RS02830	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AW03_RS02845	COG4585	Histidine kinase
AW03_RS02850	COG2197	response regulator
AW03_RS02855	COG2409	Drug exporters of the RND superfamily
AW03_RS02860	COG0596	Alpha beta hydrolase
AW03_RS02865	COG1811	Na channel or pump
AW03_RS02870	COG0789	Transcriptional regulator
AW03_RS02870	COG4978	Transcriptional regulator
AW03_RS02875	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AW03_RS02880	COG0778	Nitroreductase
AW03_RS02885	COG0346	lactoylglutathione lyase activity
AW03_RS02890	COG2259	Doxx family
AW03_RS02895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW03_RS02915	COG2323	membrane
AW03_RS02920	COG2323	membrane
AW03_RS02925	COG0071	Belongs to the small heat shock protein (HSP20) family
AW03_RS02940	COG1309	transcriptional regulator
AW03_RS02950	COG0456	acetyltransferase
AW03_RS02960	COG2814	Major facilitator Superfamily
AW03_RS02970	COG0488	(ABC) transporter
AW03_RS02975	COG1113	amino acid transport
AW03_RS02980	COG2318	DinB family
AW03_RS02985	COG1846	Transcriptional regulator
AW03_RS02990	COG2409	Drug exporters of the RND superfamily
AW03_RS02990	COG1033	growth of symbiont in host cell
AW03_RS02995	COG0778	Nitroreductase
AW03_RS03000	COG1846	Transcriptional regulator
AW03_RS03005	COG2814	Major facilitator Superfamily
AW03_RS03010	COG0730	response to heat
AW03_RS03015	COG1802	Transcriptional regulator
AW03_RS03020	COG3858	chitin binding
AW03_RS03020	COG1388	LysM domain
AW03_RS03025	COG1819	glycosyl
AW03_RS03035	COG1785	Belongs to the alkaline phosphatase family
AW03_RS03040	COG5646	InterPro IPR014922
AW03_RS03050	COG0454	-acetyltransferase
AW03_RS03055	COG1078	dGTPase activity
AW03_RS03060	COG1388	LysM domain
AW03_RS03065	COG2814	Major facilitator Superfamily
AW03_RS03070	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AW03_RS03075	COG1447	Phosphotransferase system cellobiose-specific component IIA
AW03_RS03080	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AW03_RS03085	COG2723	6-phospho-beta-galactosidase activity
AW03_RS03090	COG2188	Transcriptional regulator
AW03_RS03095	COG1940	carbohydrate kinase activity
AW03_RS03100	COG1482	cell wall glycoprotein biosynthetic process
AW03_RS03105	COG4124	Belongs to the glycosyl hydrolase 26 family
AW03_RS03150	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AW03_RS03155	COG0802	atpase or kinase
AW03_RS03160	COG1214	PFAM Peptidase M22, glycoprotease
AW03_RS03165	COG0456	acetyltransferase
AW03_RS03170	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AW03_RS03175	COG0488	(ABC) transporter
AW03_RS03180	COG0315	cyclic pyranopterin monophosphate synthase activity
AW03_RS03185	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AW03_RS03190	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AW03_RS03195	COG0805	protein transport
AW03_RS03205	COG1266	CAAX protease self-immunity
AW03_RS03215	COG0459	protein refolding
AW03_RS03220	COG1073	alpha beta
AW03_RS03225	COG0457	Tetratricopeptide repeat
AW03_RS03230	COG1063	alcohol dehydrogenase
AW03_RS03235	COG2211	Major facilitator Superfamily
AW03_RS03240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AW03_RS03245	COG1842	Phage shock protein A
AW03_RS03250	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AW03_RS03255	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AW03_RS03260	COG4260	virion core protein, lumpy skin disease virus
AW03_RS03270	COG2814	Major facilitator Superfamily
AW03_RS03275	COG1063	alcohol dehydrogenase
AW03_RS03280	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AW03_RS03285	COG0823	Involved in the tonB-independent uptake of proteins
AW03_RS03300	COG2267	carboxylic ester hydrolase activity
AW03_RS03310	COG2132	Multicopper oxidase
AW03_RS03315	COG1113	amino acid transport
AW03_RS03325	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AW03_RS03330	COG0714	Associated with various cellular activities
AW03_RS03335	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
AW03_RS03340	COG1305	Transglutaminase-like
AW03_RS03345	COG0519	Catalyzes the synthesis of GMP from XMP
AW03_RS03345	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AW03_RS03360	COG2252	PERMEase
AW03_RS03365	COG3064	Membrane
AW03_RS03375	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
AW03_RS03385	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AW03_RS03390	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AW03_RS03395	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AW03_RS03400	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AW03_RS03405	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AW03_RS03410	COG0047	phosphoribosylformylglycinamidine synthase activity
AW03_RS03415	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AW03_RS03420	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AW03_RS03425	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AW03_RS03430	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AW03_RS03435	COG0138	bifunctional purine biosynthesis protein purh
AW03_RS03440	COG0151	Belongs to the GarS family
AW03_RS03445	COG1522	sequence-specific DNA binding
AW03_RS03450	COG0531	amino acid
AW03_RS03460	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AW03_RS03465	COG1470	cell adhesion involved in biofilm formation
AW03_RS03470	COG4496	protein, YerC YecD
AW03_RS03475	COG0069	glutamate synthase activity
AW03_RS03485	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
AW03_RS03490	COG0210	DNA helicase
AW03_RS03495	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AW03_RS03500	COG4851	CamS sex pheromone cAM373 precursor
AW03_RS03505	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AW03_RS03510	COG1285	pathogenesis
AW03_RS03515	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AW03_RS03520	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AW03_RS03525	COG0154	amidase activity
AW03_RS03530	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AW03_RS03535	COG1309	transcriptional regulator
AW03_RS03540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AW03_RS03545	COG1597	lipid kinase activity
AW03_RS03550	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AW03_RS03555	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AW03_RS03565	COG5293	efflux transmembrane transporter activity
AW03_RS03605	COG5444	nuclease activity
AW03_RS03615	COG3586	endonuclease activity
AW03_RS03625	COG0457	Tetratricopeptide repeat
AW03_RS03635	COG0217	transcriptional regulatory protein
AW03_RS03645	COG1309	transcriptional regulator
AW03_RS03650	COG3631	Ketosteroid isomerase-related protein
AW03_RS03655	COG0702	epimerase
AW03_RS03670	COG3546	catalase activity
AW03_RS03675	COG0454	-acetyltransferase
AW03_RS03685	COG5578	integral membrane protein
AW03_RS03690	COG2972	Histidine kinase
AW03_RS03695	COG2207	Transcriptional regulator
AW03_RS03695	COG4753	response regulator
AW03_RS03700	COG1653	transport
AW03_RS03705	COG1175	transmembrane transport
AW03_RS03710	COG0395	ABC-type sugar transport system, permease component
AW03_RS03715	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AW03_RS03720	COG2207	Transcriptional regulator
AW03_RS03725	COG2755	lipolytic protein G-D-S-L family
AW03_RS03735	COG5578	integral membrane protein
AW03_RS03740	COG3401	FG-GAP repeat protein
AW03_RS03745	COG3401	FG-GAP repeat protein
AW03_RS03750	COG2755	lipolytic protein G-D-S-L family
AW03_RS03755	COG1874	Beta-galactosidase
AW03_RS03765	COG1653	transport
AW03_RS03770	COG4209	transmembrane transport
AW03_RS03775	COG0395	ABC-type sugar transport system, permease component
AW03_RS03780	COG1486	melibiose metabolic process
AW03_RS03785	COG2323	membrane
AW03_RS03790	COG2329	Antibiotic biosynthesis monooxygenase
AW03_RS03795	COG0346	lactoylglutathione lyase activity
AW03_RS03815	COG0670	Belongs to the BI1 family
AW03_RS03820	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AW03_RS03830	COG2124	cytochrome p450
AW03_RS03830	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AW03_RS03835	COG1368	sulfuric ester hydrolase activity
AW03_RS03840	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AW03_RS03845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AW03_RS03850	COG1442	glycosyl transferase family 8
AW03_RS03855	COG1216	Glycosyl transferase, family 2
AW03_RS03860	COG1442	glycosyl transferase family 8
AW03_RS03865	COG2223	nitrite transmembrane transporter activity
AW03_RS03870	COG1011	Hydrolase
AW03_RS03875	COG0531	amino acid
AW03_RS03880	COG1012	belongs to the aldehyde dehydrogenase family
AW03_RS03885	COG0840	transmembrane signaling receptor activity
AW03_RS03890	COG0488	(ABC) transporter
AW03_RS03900	COG0789	Transcriptional regulator
AW03_RS03905	COG2814	Major facilitator Superfamily
AW03_RS03920	COG0488	(ABC) transporter
AW03_RS03925	COG0513	Belongs to the DEAD box helicase family
AW03_RS03930	COG0456	acetyltransferase
AW03_RS03935	COG2130	NADP-dependent
AW03_RS03940	COG1120	ATPase activity
AW03_RS03945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW03_RS03950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW03_RS03955	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AW03_RS03970	COG3866	Pectate lyase
AW03_RS03975	COG0471	metal ion transport
AW03_RS03980	COG3290	protein histidine kinase activity
AW03_RS03985	COG4565	transcriptional regulatory protein
AW03_RS03990	COG3181	Tripartite tricarboxylate transporter family receptor
AW03_RS04000	COG2851	Citrate transporter
AW03_RS04005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW03_RS04010	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
AW03_RS04015	COG1254	Belongs to the acylphosphatase family
AW03_RS04020	COG2258	MOSC domain
AW03_RS04040	COG0024	Methionine aminopeptidase
AW03_RS04045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW03_RS04045	COG1263	PTS System
AW03_RS04050	COG1368	sulfuric ester hydrolase activity
AW03_RS04060	COG1115	amino acid carrier protein
AW03_RS04065	COG0531	amino acid
AW03_RS04080	COG0697	spore germination
AW03_RS04085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW03_RS04085	COG1263	PTS System
AW03_RS04090	COG0366	Alpha amylase catalytic
AW03_RS04095	COG2188	Transcriptional regulator
AW03_RS04100	COG0778	Nitroreductase
AW03_RS04105	COG0737	Belongs to the 5'-nucleotidase family
AW03_RS04110	COG0693	protein deglycase activity
AW03_RS04115	COG2814	Major facilitator Superfamily
AW03_RS04120	COG4840	Belongs to the UPF0435 family
AW03_RS04125	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AW03_RS04130	COG4980	gas vesicle protein
AW03_RS04135	COG1295	ribonuclease BN
AW03_RS04145	COG0477	Major facilitator Superfamily
AW03_RS04155	COG0387	Pfam Sodium calcium exchanger
AW03_RS04165	COG0668	transmembrane transport
AW03_RS04170	COG0535	radical SAM domain protein
AW03_RS04180	COG0726	polysaccharide deacetylase
AW03_RS04185	COG2084	Dehydrogenase
AW03_RS04190	COG0598	Magnesium transport protein CorA
AW03_RS04195	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AW03_RS04200	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AW03_RS04210	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AW03_RS04215	COG4637	Psort location Cytoplasmic, score
AW03_RS04220	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AW03_RS04225	COG0022	dehydrogenase e1 component
AW03_RS04230	COG0508	dehydrogenase complex catalyzes the overall conversion of
AW03_RS04235	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AW03_RS04240	COG3284	Transcriptional regulator
AW03_RS04250	COG1742	UPF0060 membrane protein
AW03_RS04270	COG4842	Belongs to the WXG100 family
AW03_RS04275	COG1486	melibiose metabolic process
AW03_RS04280	COG1737	Transcriptional regulator
AW03_RS04285	COG1263	PTS System
AW03_RS04285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW03_RS04290	COG1132	(ABC) transporter
AW03_RS04295	COG1132	(ABC) transporter
AW03_RS04300	COG2259	Doxx family
AW03_RS04305	COG2514	catechol 2,3-dioxygenase activity
AW03_RS04310	COG4585	Histidine kinase
AW03_RS04315	COG2197	response regulator
AW03_RS04320	COG1131	(ABC) transporter
AW03_RS04325	COG1511	domain protein
AW03_RS04325	COG0842	Transport permease protein
AW03_RS04330	COG0842	Transport permease protein
AW03_RS04340	COG1695	Transcriptional regulator
AW03_RS04345	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AW03_RS04365	COG1131	(ABC) transporter
AW03_RS04370	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
AW03_RS04375	COG1309	transcriptional regulator
AW03_RS04380	COG2814	Major facilitator Superfamily
AW03_RS04385	COG2318	DinB family
AW03_RS04390	COG2814	Major facilitator Superfamily
AW03_RS04395	COG1846	Transcriptional regulator
AW03_RS04400	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AW03_RS04400	COG0392	lysyltransferase activity
AW03_RS04405	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW03_RS04410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW03_RS04415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW03_RS04420	COG0384	phenazine biosynthesis protein PhzF
AW03_RS04425	COG0778	Nitroreductase
AW03_RS04440	COG1090	epimerase
AW03_RS04445	COG2137	regulation of response to DNA damage stimulus
AW03_RS04460	COG2814	Major facilitator Superfamily
AW03_RS04475	COG3103	Sh3 type 3 domain protein
AW03_RS04480	COG5658	integral membrane protein
AW03_RS04485	COG0596	Alpha beta hydrolase
AW03_RS04490	COG0463	Glycosyl transferase, family 2
AW03_RS04495	COG4485	Bacterial membrane protein, YfhO
AW03_RS04500	COG1988	membrane-bound metal-dependent
AW03_RS04505	COG1194	a g-specific adenine glycosylase
AW03_RS04515	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_RS04530	COG3557	Belongs to the UPF0374 family
AW03_RS04535	COG1132	(ABC) transporter
AW03_RS04540	COG4129	membrane
AW03_RS04545	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AW03_RS04550	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AW03_RS04555	COG0735	belongs to the Fur family
AW03_RS04670	COG4326	sporulation control protein
AW03_RS04680	COG5577	PFAM Coat F domain
AW03_RS04685	COG3340	Belongs to the peptidase S51 family
AW03_RS04690	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AW03_RS04700	COG0753	catalase activity
AW03_RS04705	COG1116	anion transmembrane transporter activity
AW03_RS04710	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AW03_RS04715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AW03_RS04720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AW03_RS04730	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AW03_RS04740	COG1476	TRANSCRIPTIONal
AW03_RS04750	COG3382	B3 4 domain protein
AW03_RS04755	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AW03_RS04765	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AW03_RS04770	COG0789	Transcriptional regulator
AW03_RS04775	COG1664	Polymer-forming cytoskeletal
AW03_RS04780	COG1664	Polymer-forming cytoskeletal
AW03_RS04785	COG2766	serine protein kinase
AW03_RS04790	COG2718	Belongs to the UPF0229 family
AW03_RS04800	COG1846	Transcriptional regulator
AW03_RS04805	COG1566	PFAM secretion protein HlyD family protein
AW03_RS04810	COG2814	Major facilitator Superfamily
AW03_RS04815	COG0655	NAD(P)H dehydrogenase (quinone) activity
AW03_RS04830	COG1725	Transcriptional regulator
AW03_RS04835	COG1131	(ABC) transporter
AW03_RS04840	COG1131	(ABC) transporter
AW03_RS04845	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AW03_RS04850	COG1278	Cold shock
AW03_RS04855	COG1464	Belongs to the NlpA lipoprotein family
AW03_RS04860	COG3706	GGDEF domain
AW03_RS04865	COG1823	symporter activity
AW03_RS04885	COG5577	PFAM Coat F domain
AW03_RS04890	COG4085	toxin activity
AW03_RS04890	COG0737	Belongs to the 5'-nucleotidase family
AW03_RS04890	COG1525	nuclease
AW03_RS04895	COG3764	Sortase (surface protein transpeptidase)
AW03_RS04900	COG0564	pseudouridine synthase activity
AW03_RS04910	COG0517	IMP dehydrogenase activity
AW03_RS04915	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AW03_RS04920	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AW03_RS04920	COG3153	acetyltransferase
AW03_RS04925	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AW03_RS04930	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AW03_RS04935	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AW03_RS04940	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AW03_RS04945	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AW03_RS04950	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AW03_RS04955	COG4585	Histidine kinase
AW03_RS04955	COG2203	Gaf domain
AW03_RS04960	COG2197	response regulator
AW03_RS04965	COG0431	NADPH-dependent FMN reductase
AW03_RS04980	COG0791	NLP P60 protein
AW03_RS04980	COG1388	LysM domain
AW03_RS04985	COG1959	2 iron, 2 sulfur cluster binding
AW03_RS04990	COG0668	transmembrane transport
AW03_RS04995	COG2719	SpoVR family
AW03_RS05000	COG1785	Belongs to the alkaline phosphatase family
AW03_RS05005	COG0791	NLP P60 protein
AW03_RS05005	COG1388	LysM domain
AW03_RS05010	COG0583	DNA-binding transcription factor activity
AW03_RS05015	COG0372	Belongs to the citrate synthase family
AW03_RS05020	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_RS05025	COG0531	amino acid
AW03_RS05030	COG0733	neurotransmitter:sodium symporter activity
AW03_RS05035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW03_RS05040	COG0456	acetyltransferase
AW03_RS05055	COG1595	DNA-templated transcription, initiation
AW03_RS05060	COG0667	Aldo Keto reductase
AW03_RS05065	COG0204	Acyl-transferase
AW03_RS05070	COG1253	flavin adenine dinucleotide binding
AW03_RS05075	COG0789	Transcriptional regulator
AW03_RS05080	COG0436	Aminotransferase
AW03_RS05085	COG1253	flavin adenine dinucleotide binding
AW03_RS05090	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AW03_RS05095	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AW03_RS05100	COG0584	glycerophosphoryl diester phosphodiesterase
AW03_RS05110	COG0668	transmembrane transport
AW03_RS05115	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AW03_RS05120	COG0726	polysaccharide deacetylase
AW03_RS05125	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AW03_RS05130	COG1757	Na H antiporter
AW03_RS05135	COG0589	response to stress
AW03_RS05145	COG1132	(ABC) transporter
AW03_RS05150	COG1132	(ABC) transporter
AW03_RS05155	COG0702	epimerase
AW03_RS05170	COG0189	ligase activity
AW03_RS05175	COG0189	ligase activity
AW03_RS05180	COG4399	Belongs to the UPF0754 family
AW03_RS05185	COG3679	Belongs to the UPF0342 family
AW03_RS05190	COG4335	DNA alkylation repair
AW03_RS05195	COG0561	phosphatase activity
AW03_RS05200	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AW03_RS05205	COG0475	glutathione-regulated potassium exporter activity
AW03_RS05210	COG0490	domain, Protein
AW03_RS05220	COG1024	Enoyl-CoA hydratase
AW03_RS05230	COG4152	abc transporter atp-binding protein
AW03_RS05235	COG1668	transmembrane transport
AW03_RS05240	COG0420	3'-5' exonuclease activity
AW03_RS05245	COG4717	serine-type aminopeptidase activity
AW03_RS05250	COG3481	metal-dependent phosphohydrolase, HD sub domain
AW03_RS05260	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AW03_RS05285	COG1846	Transcriptional regulator
AW03_RS05290	COG4980	gas vesicle protein
AW03_RS05305	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AW03_RS05310	COG0537	adenosine 5'-monophosphoramidase activity
AW03_RS05315	COG1131	(ABC) transporter
AW03_RS05320	COG4473	ABC transporter
AW03_RS05330	COG1473	amidohydrolase
AW03_RS05335	COG3069	C4-dicarboxylate transmembrane transporter activity
AW03_RS05345	COG2329	Antibiotic biosynthesis monooxygenase
AW03_RS05350	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AW03_RS05355	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AW03_RS05360	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AW03_RS05365	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AW03_RS05370	COG1309	transcriptional regulator
AW03_RS05375	COG1511	domain protein
AW03_RS05380	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AW03_RS05385	COG4377	Putative membrane peptidase family (DUF2324)
AW03_RS05395	COG1363	Peptidase, m42
AW03_RS05400	COG4405	Protein conserved in bacteria
AW03_RS05405	COG1301	dicarboxylic acid transport
AW03_RS05415	COG1234	tRNA 3'-trailer cleavage
AW03_RS05420	COG0095	Lipoate-protein ligase
AW03_RS05425	COG0702	epimerase
AW03_RS05430	COG0318	PFAM AMP-dependent synthetase and ligase
AW03_RS05440	COG0501	Belongs to the peptidase M48B family
AW03_RS05445	COG1404	Belongs to the peptidase S8 family
AW03_RS05455	COG0604	alcohol dehydrogenase
AW03_RS05460	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AW03_RS05465	COG0406	alpha-ribazole phosphatase activity
AW03_RS05470	COG0183	Belongs to the thiolase family
AW03_RS05475	COG0318	PFAM AMP-dependent synthetase and ligase
AW03_RS05480	COG1268	BioY protein
AW03_RS05485	COG0840	transmembrane signaling receptor activity
AW03_RS05490	COG0723	plastoquinol--plastocyanin reductase activity
AW03_RS05490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AW03_RS05495	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_RS05505	COG4903	ComK protein
AW03_RS05510	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_RS05520	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AW03_RS05535	COG0398	Pfam SNARE associated Golgi protein
AW03_RS05540	COG0681	Belongs to the peptidase S26 family
AW03_RS05545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AW03_RS05550	COG1846	Transcriptional regulator
AW03_RS05555	COG0738	Major facilitator superfamily
AW03_RS05560	COG0673	inositol 2-dehydrogenase activity
AW03_RS05565	COG0561	phosphatase activity
AW03_RS05570	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AW03_RS05575	COG1609	Transcriptional regulator
AW03_RS05580	COG3180	Ammonia monooxygenase
AW03_RS05585	COG0477	Major facilitator Superfamily
AW03_RS05585	COG2814	Major facilitator Superfamily
AW03_RS05590	COG4533	DNA binding
AW03_RS05600	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
AW03_RS05605	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AW03_RS05610	COG1074	ATP-dependent DNA helicase activity
AW03_RS05615	COG0420	3'-5' exonuclease activity
AW03_RS05620	COG0419	ATPase involved in DNA repair
AW03_RS05625	COG1403	HNH endonuclease
AW03_RS05670	COG5337	Spore coat protein CotH
AW03_RS05675	COG0179	Fumarylacetoacetate (FAA) hydrolase
AW03_RS05685	COG1404	Belongs to the peptidase S8 family
AW03_RS05695	COG0367	asparagine synthase
AW03_RS05700	COG1562	ergosterol biosynthetic process
AW03_RS05705	COG0534	Mate efflux family protein
AW03_RS05710	COG1917	Cupin 2, conserved barrel domain protein
AW03_RS05710	COG2207	Transcriptional regulator
AW03_RS05715	COG1609	Transcriptional regulator
AW03_RS05720	COG0673	inositol 2-dehydrogenase activity
AW03_RS05725	COG2318	DinB family
AW03_RS05730	COG1279	arginine transmembrane transporter activity
AW03_RS05735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW03_RS05740	COG1357	PFAM Pentapeptide repeats (8 copies)
AW03_RS05745	COG2267	carboxylic ester hydrolase activity
AW03_RS05750	COG0529	Catalyzes the synthesis of activated sulfate
AW03_RS05755	COG2046	Belongs to the sulfate adenylyltransferase family
AW03_RS05760	COG0175	sulfate reduction
AW03_RS05765	COG2045	Belongs to the ComB family
AW03_RS05770	COG1809	phosphosulfolactate synthase activity
AW03_RS05775	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW03_RS05780	COG4948	Mandelate Racemase Muconate Lactonizing
AW03_RS05785	COG2814	Major facilitator Superfamily
AW03_RS05790	COG0454	-acetyltransferase
AW03_RS05795	COG2153	protein acetylation
AW03_RS05800	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AW03_RS05800	COG0646	methionine synthase
AW03_RS05810	COG2996	Protein conserved in bacteria
AW03_RS05830	COG1695	Transcriptional regulator
AW03_RS05845	COG3227	Zinc metalloprotease (Elastase)
AW03_RS05850	COG1307	EDD domain protein, DegV family
AW03_RS05855	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW03_RS05875	COG0561	phosphatase activity
AW03_RS05880	COG1073	alpha beta
AW03_RS05885	COG2151	metal-sulfur cluster biosynthetic enzyme
AW03_RS05895	COG0277	FAD linked oxidase domain protein
AW03_RS05900	COG2271	Major facilitator Superfamily
AW03_RS05905	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AW03_RS05910	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AW03_RS05920	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AW03_RS05925	COG0505	Belongs to the CarA family
AW03_RS05930	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AW03_RS05935	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AW03_RS05950	COG2267	carboxylic ester hydrolase activity
AW03_RS05960	COG1744	ABC transporter substrate-binding protein PnrA-like
AW03_RS05975	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AW03_RS05980	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AW03_RS05985	COG5504	Zn-dependent protease
AW03_RS05990	COG0444	Belongs to the ABC transporter superfamily
AW03_RS05995	COG4608	Belongs to the ABC transporter superfamily
AW03_RS06005	COG0601	transmembrane transport
AW03_RS06010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AW03_RS06020	COG0180	Tryptophanyl-tRNA synthetase
AW03_RS06025	COG4166	transmembrane transport
AW03_RS06030	COG0601	transmembrane transport
AW03_RS06035	COG0444	Belongs to the ABC transporter superfamily
AW03_RS06040	COG4608	Belongs to the ABC transporter superfamily
AW03_RS06045	COG2814	Major facilitator Superfamily
AW03_RS06050	COG0456	acetyltransferase
AW03_RS06055	COG1393	Belongs to the ArsC family
AW03_RS06060	COG0861	Integral membrane protein TerC family
AW03_RS06065	COG4862	establishment of competence for transformation
AW03_RS06070	COG4469	Competence protein
AW03_RS06075	COG1164	Oligoendopeptidase f
AW03_RS06090	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AW03_RS06095	COG2346	COG2346, Truncated hemoglobins
AW03_RS06100	COG0741	lytic transglycosylase activity
AW03_RS06105	COG4116	CYTH
AW03_RS06115	COG2357	RelA SpoT domain protein
AW03_RS06120	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AW03_RS06125	COG0564	pseudouridine synthase activity
AW03_RS06130	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AW03_RS06135	COG0569	domain protein
AW03_RS06135	COG0475	glutathione-regulated potassium exporter activity
AW03_RS06140	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AW03_RS06145	COG0352	thiamine-phosphate diphosphorylase activity
AW03_RS06150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AW03_RS06155	COG2104	thiamine diphosphate biosynthetic process
AW03_RS06160	COG2022	thiamine diphosphate biosynthetic process
AW03_RS06165	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AW03_RS06170	COG0351	phosphomethylpyrimidine kinase
AW03_RS06175	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AW03_RS06230	COG0210	DNA helicase
AW03_RS06240	COG2153	protein acetylation
AW03_RS06245	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AW03_RS06250	COG2382	esterase
AW03_RS06255	COG0626	cystathionine gamma-synthase activity
AW03_RS06260	COG0626	cystathionine gamma-synthase activity
AW03_RS06265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW03_RS06270	COG5505	Protein of unknown function (DUF819)
AW03_RS06315	COG0457	Tetratricopeptide repeat
AW03_RS06320	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AW03_RS06330	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW03_RS06330	COG3711	transcriptional antiterminator
AW03_RS06335	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW03_RS06335	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AW03_RS06335	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AW03_RS06340	COG1482	cell wall glycoprotein biosynthetic process
AW03_RS06350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW03_RS06360	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AW03_RS06375	COG0109	protoheme IX farnesyltransferase activity
AW03_RS06385	COG0726	polysaccharide deacetylase
AW03_RS06405	COG5504	Zn-dependent protease
AW03_RS06410	COG2205	protein histidine kinase activity
AW03_RS06420	COG3383	formate dehydrogenase (NAD+) activity
AW03_RS06425	COG2427	Protein of unknown function (DUF1641)
AW03_RS06435	COG1051	belongs to the nudix hydrolase family
AW03_RS06445	COG2124	cytochrome p450
AW03_RS06450	COG1819	glycosyl
AW03_RS06460	COG1587	Uroporphyrinogen-III synthase
AW03_RS06465	COG0390	transport system, permease component
AW03_RS06470	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AW03_RS06475	COG0697	spore germination
AW03_RS06480	COG4297	protein containing double-stranded beta helix domain
AW03_RS06490	COG1252	NADH dehydrogenase
AW03_RS06495	COG1904	glucuronate isomerase
AW03_RS06500	COG2211	Major facilitator Superfamily
AW03_RS06505	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AW03_RS06510	COG1063	alcohol dehydrogenase
AW03_RS06515	COG1312	Catalyzes the dehydration of D-mannonate
AW03_RS06520	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_RS06525	COG2271	Major facilitator Superfamily
AW03_RS06530	COG1609	Transcriptional regulator
AW03_RS06535	COG0246	Mannitol dehydrogenase
AW03_RS06540	COG2721	sulfolactate sulfo-lyase activity
AW03_RS06545	COG0730	response to heat
AW03_RS06550	COG2318	DinB family
AW03_RS06555	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AW03_RS06560	COG0457	Tetratricopeptide repeat
AW03_RS06570	COG2350	Protein conserved in bacteria
AW03_RS06575	COG5632	N-Acetylmuramoyl-L-alanine amidase
AW03_RS06575	COG1388	LysM domain
AW03_RS06575	COG3409	Peptidoglycan-binding domain 1 protein
AW03_RS06585	COG4195	phage-related replication protein
AW03_RS06590	COG3546	catalase activity
AW03_RS06595	COG2856	Zn peptidase
AW03_RS06600	COG1396	sequence-specific DNA binding
AW03_RS06610	COG1522	sequence-specific DNA binding
AW03_RS06615	COG1484	DNA-dependent DNA replication
AW03_RS06640	COG1595	DNA-templated transcription, initiation
AW03_RS06645	COG3728	DNA packaging
AW03_RS06645	COG5484	DNA packaging
AW03_RS06650	COG1783	phage Terminase large subunit
AW03_RS06655	COG5518	Phage portal protein
AW03_RS06660	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AW03_RS06665	COG4653	Phage capsid family
AW03_RS06715	COG5412	phage tail tape measure protein
AW03_RS06715	COG3953	SLT domain
AW03_RS06720	COG1652	LysM domain
AW03_RS06725	COG4193	domain, Protein
AW03_RS06735	COG3628	GPW Gp25 family protein
AW03_RS06740	COG3299	homolog of phage Mu protein gp47
AW03_RS06745	COG3778	Protein conserved in bacteria
AW03_RS06785	COG5632	N-Acetylmuramoyl-L-alanine amidase
AW03_RS06785	COG3409	Peptidoglycan-binding domain 1 protein
AW03_RS06800	COG0306	phosphate transporter
AW03_RS06805	COG1392	Phosphate transport regulator
AW03_RS06810	COG0531	amino acid
AW03_RS06815	COG0346	lactoylglutathione lyase activity
AW03_RS06820	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AW03_RS06825	COG0463	Glycosyl transferase, family 2
AW03_RS06840	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AW03_RS06845	COG2362	D-Aminopeptidase
AW03_RS06850	COG0601	transmembrane transport
AW03_RS06855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AW03_RS06860	COG0444	Belongs to the ABC transporter superfamily
AW03_RS06865	COG4166	transmembrane transport
AW03_RS06870	COG1619	proteins homologs of microcin C7 resistance protein MccF
AW03_RS06875	COG4948	Mandelate Racemase Muconate Lactonizing
AW03_RS06880	COG0791	NLP P60 protein
AW03_RS06885	COG4608	Belongs to the ABC transporter superfamily
AW03_RS06890	COG2706	6-phosphogluconolactonase activity
AW03_RS06895	COG1834	amidinotransferase
AW03_RS06900	COG1607	acyl-coa hydrolase
AW03_RS06905	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AW03_RS06905	COG1017	nitric oxide dioxygenase activity
AW03_RS06915	COG2323	membrane
AW03_RS06920	COG2318	DinB family
AW03_RS06925	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW03_RS06930	COG2076	Multidrug Resistance protein
AW03_RS06935	COG2076	Multidrug Resistance protein
AW03_RS06940	COG0788	formyltetrahydrofolate deformylase activity
AW03_RS06945	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AW03_RS06950	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AW03_RS06955	COG1764	response to oxidative stress
AW03_RS06960	COG1846	Transcriptional regulator
AW03_RS06965	COG1764	response to oxidative stress
AW03_RS06975	COG0590	tRNA wobble adenosine to inosine editing
AW03_RS06985	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AW03_RS06990	COG1404	Belongs to the peptidase S8 family
AW03_RS06995	COG1366	Belongs to the anti-sigma-factor antagonist family
AW03_RS07000	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AW03_RS07005	COG1122	ATPase activity
AW03_RS07010	COG4721	ABC-type cobalt transport system, permease component
AW03_RS07020	COG0745	RESPONSE REGULATOR receiver
AW03_RS07025	COG5002	protein histidine kinase activity
AW03_RS07025	COG3850	Histidine kinase
AW03_RS07030	COG3212	peptidase
AW03_RS07035	COG3212	peptidase
AW03_RS07055	COG2239	Acts as a magnesium transporter
AW03_RS07060	COG0789	Transcriptional regulator
AW03_RS07075	COG1846	Transcriptional regulator
AW03_RS07080	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AW03_RS07085	COG0726	polysaccharide deacetylase
AW03_RS07090	COG1408	metallophosphoesterase
AW03_RS07100	COG0463	Glycosyl transferase, family 2
AW03_RS07105	COG3285	dna ligase
AW03_RS07105	COG1793	dna ligase
AW03_RS07110	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AW03_RS07115	COG3300	MHYT domain
AW03_RS07115	COG5001	Diguanylate cyclase
AW03_RS07120	COG0586	Pfam SNARE associated Golgi protein
AW03_RS07125	COG0861	Integral membrane protein TerC family
AW03_RS07130	COG1191	sigma factor activity
AW03_RS07150	COG0501	Belongs to the peptidase M48B family
AW03_RS07155	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AW03_RS07170	COG3594	Acyltransferase
AW03_RS07175	COG5002	protein histidine kinase activity
AW03_RS07180	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AW03_RS07190	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AW03_RS07195	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
AW03_RS07200	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AW03_RS07205	COG0436	Aminotransferase
AW03_RS07210	COG1850	ribulose-bisphosphate carboxylase activity
AW03_RS07215	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
AW03_RS07220	COG0235	Class ii aldolase
AW03_RS07225	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AW03_RS07230	COG3339	Conserved Protein
AW03_RS07245	COG3852	Histidine kinase
AW03_RS07250	COG1846	Transcriptional regulator
AW03_RS07255	COG1360	Flagellar Motor Protein
AW03_RS07260	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AW03_RS07265	COG0542	response to heat
AW03_RS07270	COG3949	Membrane
AW03_RS07275	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AW03_RS07280	COG0720	synthase
AW03_RS07285	COG0602	queuosine metabolic process
AW03_RS07290	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AW03_RS07295	COG4641	Protein conserved in bacteria
AW03_RS07295	COG1388	LysM domain
AW03_RS07300	COG1388	LysM domain
AW03_RS07305	COG3858	chitin binding
AW03_RS07315	COG4873	Protein conserved in bacteria
AW03_RS07335	COG2244	polysaccharide biosynthetic process
AW03_RS07340	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW03_RS07345	COG2217	Heavy metal translocating P-type atpase
AW03_RS07355	COG0006	proline dipeptidase activity
AW03_RS07365	COG1609	Transcriptional regulator
AW03_RS07370	COG3711	transcriptional antiterminator
AW03_RS07375	COG1263	PTS System
AW03_RS07375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW03_RS07375	COG2190	(PTS) system
AW03_RS07380	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW03_RS07385	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AW03_RS07395	COG1533	DNA photolyase activity
AW03_RS07400	COG0456	acetyltransferase
AW03_RS07405	COG0840	transmembrane signaling receptor activity
AW03_RS07410	COG2084	Dehydrogenase
AW03_RS07415	COG2340	Cysteine-rich secretory protein family
AW03_RS07420	COG0768	penicillin binding
AW03_RS07425	COG4191	Histidine kinase
AW03_RS07430	COG0436	Aminotransferase
AW03_RS07440	COG0835	chemotaxis
AW03_RS07440	COG0784	Response regulator, receiver
AW03_RS07450	COG2814	Major facilitator Superfamily
AW03_RS07455	COG1376	ErfK ybiS ycfS ynhG family protein
AW03_RS07460	COG1408	metallophosphoesterase
AW03_RS07465	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_RS07470	COG2200	EAL domain
AW03_RS07480	COG4703	Protein of unknown function (DUF1797)
AW03_RS07485	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
AW03_RS07495	COG0517	IMP dehydrogenase activity
AW03_RS07500	COG0583	DNA-binding transcription factor activity
AW03_RS07505	COG0716	FMN binding
AW03_RS07515	COG0716	FMN binding
AW03_RS07520	COG2171	N-acyltransferase activity
AW03_RS07525	COG1473	amidohydrolase
AW03_RS07535	COG0668	transmembrane transport
AW03_RS07540	COG0450	alkyl hydroperoxide reductase
AW03_RS07545	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW03_RS07560	COG0746	molybdenum cofactor guanylyltransferase activity
AW03_RS07565	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AW03_RS07570	COG0303	'Molybdopterin
AW03_RS07575	COG1763	Mo-molybdopterin cofactor biosynthetic process
AW03_RS07580	COG0314	molybdopterin synthase activity
AW03_RS07585	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AW03_RS07590	COG1132	(ABC) transporter
AW03_RS07595	COG1132	(ABC) transporter
AW03_RS07605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AW03_RS07610	COG1136	(ABC) transporter
AW03_RS07615	COG0577	efflux transmembrane transporter activity
AW03_RS07620	COG1349	DNA-binding transcription factor activity
AW03_RS07625	COG1105	Belongs to the carbohydrate kinase PfkB family
AW03_RS07630	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW03_RS07630	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AW03_RS07630	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AW03_RS07635	COG0681	Belongs to the peptidase S26 family
AW03_RS07645	COG0488	(ABC) transporter
AW03_RS07655	COG2309	aminopeptidase activity
AW03_RS07665	COG1077	Cell shape determining protein MreB Mrl
AW03_RS07670	COG2002	toxin-antitoxin pair type II binding
AW03_RS07675	COG3852	Histidine kinase
AW03_RS07680	COG2105	PFAM AIG2 family protein
AW03_RS07680	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AW03_RS07685	COG0569	domain protein
AW03_RS07690	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AW03_RS07695	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AW03_RS07700	COG5503	Protein of unknown function (DUF1447)
AW03_RS07705	COG0561	phosphatase activity
AW03_RS07710	COG0242	peptide deformylase activity
AW03_RS07720	COG0497	DNA recombination
AW03_RS07725	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AW03_RS07730	COG0022	dehydrogenase e1 component
AW03_RS07735	COG0508	dehydrogenase complex catalyzes the overall conversion of
AW03_RS07740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AW03_RS07745	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW03_RS07750	COG1982	Orn Lys Arg decarboxylase major
AW03_RS07755	COG4476	Belongs to the UPF0223 family
AW03_RS07760	COG4493	Belongs to the UPF0637 family
AW03_RS07770	COG0483	inositol monophosphate 1-phosphatase activity
AW03_RS07780	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AW03_RS07800	COG1595	DNA-templated transcription, initiation
AW03_RS07820	COG1217	gtp-binding protein TYPA
AW03_RS07830	COG4896	Protein conserved in bacteria
AW03_RS07840	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AW03_RS07845	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AW03_RS07850	COG2066	Belongs to the glutaminase family
AW03_RS07855	COG4838	Belongs to the UPF0358 family
AW03_RS07860	COG0772	Belongs to the SEDS family
AW03_RS07865	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AW03_RS07870	COG1612	heme a metabolic process
AW03_RS07875	COG0109	protoheme IX farnesyltransferase activity
AW03_RS07880	COG2010	Cytochrome c
AW03_RS07880	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AW03_RS07885	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AW03_RS07890	COG1845	cytochrome c oxidase, subunit III
AW03_RS07895	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AW03_RS07900	COG3336	cytochrome c oxidase
AW03_RS07910	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
AW03_RS07915	COG2340	Cysteine-rich secretory protein family
AW03_RS07930	COG3679	Belongs to the UPF0342 family
AW03_RS07935	COG4471	UPF0298 protein
AW03_RS07940	COG0742	ribosomal rna small subunit methyltransferase
AW03_RS07945	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AW03_RS07950	COG3314	Sporulation integral membrane protein YlbJ
AW03_RS07955	COG1752	Esterase of the alpha-beta hydrolase superfamily
AW03_RS07960	COG3480	Lon protease (S16) C-terminal proteolytic domain
AW03_RS07980	COG1399	metal-binding, possibly nucleic acid-binding protein
AW03_RS07995	COG0454	-acetyltransferase
AW03_RS08000	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AW03_RS08005	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
AW03_RS08010	COG2001	Belongs to the MraZ family
AW03_RS08015	COG0275	rRNA processing
AW03_RS08020	COG4839	cell division protein FtsL
AW03_RS08025	COG0768	penicillin binding
AW03_RS08035	COG0768	penicillin binding
AW03_RS08045	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AW03_RS08055	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AW03_RS08060	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AW03_RS08065	COG0772	Belongs to the SEDS family
AW03_RS08070	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AW03_RS08075	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AW03_RS08080	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AW03_RS08085	COG3879	Bacterial protein of unknown function (DUF881)
AW03_RS08090	COG3879	Bacterial protein of unknown function (DUF881)
AW03_RS08095	COG3856	small basic protein
AW03_RS08100	COG0849	cell division
AW03_RS08105	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AW03_RS08110	COG1404	Belongs to the peptidase S8 family
AW03_RS08110	COG4412	M6 family metalloprotease domain protein
AW03_RS08120	COG1191	sigma factor activity
AW03_RS08125	COG1191	sigma factor activity
AW03_RS08130	COG1119	ATPase activity
AW03_RS08135	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AW03_RS08140	COG1873	PFAM PRC-barrel domain
AW03_RS08145	COG1496	oxidoreductase activity
AW03_RS08150	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AW03_RS08155	COG1799	cell septum assembly
AW03_RS08160	COG0762	integral membrane protein
AW03_RS08165	COG2302	S4 RNA-binding domain
AW03_RS08170	COG3599	regulation of cell shape
AW03_RS08175	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AW03_RS08180	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AW03_RS08185	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AW03_RS08190	COG0564	pseudouridine synthase activity
AW03_RS08195	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AW03_RS08200	COG2233	PERMEase
AW03_RS08205	COG0540	Belongs to the ATCase OTCase family
AW03_RS08210	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AW03_RS08215	COG0505	Belongs to the CarA family
AW03_RS08220	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AW03_RS08225	COG0543	2 iron, 2 sulfur cluster binding
AW03_RS08230	COG0167	dihydroorotate dehydrogenase activity
AW03_RS08235	COG0284	orotidine-5'-phosphate decarboxylase activity
AW03_RS08240	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AW03_RS08250	COG0175	sulfate reduction
AW03_RS08255	COG0306	phosphate transporter
AW03_RS08260	COG2046	Belongs to the sulfate adenylyltransferase family
AW03_RS08265	COG0529	Catalyzes the synthesis of activated sulfate
AW03_RS08270	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AW03_RS08275	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
AW03_RS08280	COG1648	precorrin-2 dehydrogenase activity
AW03_RS08285	COG1293	RNA-binding protein homologous to eukaryotic snRNP
AW03_RS08290	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AW03_RS08295	COG1561	YicC-like family, N-terminal region
AW03_RS08305	COG0194	GDP metabolic process
AW03_RS08310	COG1758	RNA polymerase activity
AW03_RS08315	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AW03_RS08320	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AW03_RS08325	COG0242	peptide deformylase activity
AW03_RS08330	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AW03_RS08335	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AW03_RS08335	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AW03_RS08340	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AW03_RS08345	COG0631	protein serine/threonine phosphatase activity
AW03_RS08350	COG2815	serine threonine protein kinase
AW03_RS08350	COG0515	serine threonine protein kinase
AW03_RS08355	COG1162	GTPase activity
AW03_RS08360	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AW03_RS08365	COG1564	THIamine pyrophosphokinase
AW03_RS08375	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AW03_RS08380	COG1302	Protein conserved in bacteria
AW03_RS08385	COG1461	Dihydroxyacetone kinase
AW03_RS08390	COG1760	l-serine dehydratase
AW03_RS08395	COG1760	l-serine dehydratase
AW03_RS08400	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AW03_RS08405	COG1349	DNA-binding transcription factor activity
AW03_RS08405	COG2050	protein possibly involved in aromatic compounds catabolism
AW03_RS08410	COG0416	fatty acid biosynthetic process
AW03_RS08415	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AW03_RS08420	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_RS08430	COG0571	ribonuclease III activity
AW03_RS08435	COG1196	nuclear chromosome segregation
AW03_RS08440	COG0552	protein localization to endoplasmic reticulum
AW03_RS08450	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AW03_RS08455	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AW03_RS08460	COG0228	four-way junction DNA binding
AW03_RS08465	COG1837	Belongs to the UPF0109 family
AW03_RS08475	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AW03_RS08480	COG0336	Belongs to the RNA methyltransferase TrmD family
AW03_RS08485	COG0335	large ribosomal subunit rRNA binding
AW03_RS08490	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AW03_RS08495	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AW03_RS08505	COG2257	FlhB HrpN YscU SpaS Family
AW03_RS08510	COG0045	succinate-CoA ligase (ADP-forming) activity
AW03_RS08515	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AW03_RS08520	COG0758	DNA mediated transformation
AW03_RS08525	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AW03_RS08530	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AW03_RS08535	COG4974	Belongs to the 'phage' integrase family
AW03_RS08540	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AW03_RS08545	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AW03_RS08550	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AW03_RS08555	COG1815	bacterial-type flagellum-dependent cell motility
AW03_RS08560	COG1558	bacterial-type flagellum-dependent cell motility
AW03_RS08565	COG1677	Flagellar hook-basal body complex protein FliE
AW03_RS08570	COG1766	The M ring may be actively involved in energy transduction
AW03_RS08575	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AW03_RS08580	COG1317	bacterial-type flagellum organization
AW03_RS08585	COG1157	protein secretion by the type III secretion system
AW03_RS08590	COG2882	bacterial-type flagellum organization
AW03_RS08595	COG3334	PFAM MgtE intracellular
AW03_RS08600	COG3144	bacterial-type flagellum assembly
AW03_RS08605	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AW03_RS08610	COG4786	Flagellar basal body rod
AW03_RS08615	COG1582	Flagellar protein (FlbD)
AW03_RS08620	COG1580	Controls the rotational direction of flagella during chemotaxis
AW03_RS08625	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AW03_RS08630	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AW03_RS08630	COG1776	CheC inhibitor of MCP methylation
AW03_RS08635	COG2201	protein-glutamate methylesterase activity
AW03_RS08640	COG3190	flagellar
AW03_RS08645	COG1338	Plays a role in the flagellum-specific transport system
AW03_RS08650	COG1987	bacterial-type flagellum assembly
AW03_RS08655	COG1684	flagellar biosynthetic protein fliR
AW03_RS08660	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AW03_RS08665	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AW03_RS08670	COG1419	protein localization to endoplasmic reticulum
AW03_RS08675	COG0455	bacterial-type flagellum organization
AW03_RS08680	COG2201	protein-glutamate methylesterase activity
AW03_RS08685	COG0643	Histidine kinase
AW03_RS08685	COG2198	Histidine kinase
AW03_RS08690	COG0835	chemotaxis
AW03_RS08695	COG1776	CheC inhibitor of MCP methylation
AW03_RS08700	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AW03_RS08705	COG1191	sigma factor activity
AW03_RS08715	COG0052	Belongs to the universal ribosomal protein uS2 family
AW03_RS08720	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AW03_RS08725	COG0528	UMP kinase activity
AW03_RS08730	COG0233	cytoplasmic translational termination
AW03_RS08735	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AW03_RS08740	COG4589	Belongs to the CDS family
AW03_RS08745	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AW03_RS08750	COG0750	zinc metalloprotease
AW03_RS08755	COG0442	prolyl-tRNA aminoacylation
AW03_RS08760	COG2176	DNA-directed DNA polymerase activity
AW03_RS08765	COG0779	Required for maturation of 30S ribosomal subunits
AW03_RS08770	COG0195	Participates in both transcription termination and antitermination
AW03_RS08775	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AW03_RS08780	COG1358	cellular component organization or biogenesis
AW03_RS08785	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AW03_RS08790	COG1550	Protein conserved in bacteria
AW03_RS08795	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AW03_RS08800	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AW03_RS08805	COG0196	riboflavin kinase activity
AW03_RS08810	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AW03_RS08815	COG1185	polyribonucleotide nucleotidyltransferase activity
AW03_RS08820	COG0726	polysaccharide deacetylase
AW03_RS08825	COG0612	Peptidase, M16
AW03_RS08830	COG1873	PFAM PRC-barrel domain
AW03_RS08840	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AW03_RS08845	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AW03_RS08850	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AW03_RS08855	COG0527	aspartate kinase activity
AW03_RS08860	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AW03_RS08865	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AW03_RS08870	COG0740	serine-type endopeptidase activity
AW03_RS08880	COG4980	gas vesicle protein
AW03_RS08880	COG1674	ftsk spoiiie
AW03_RS08885	COG2188	Transcriptional regulator
AW03_RS08890	COG2814	Major facilitator Superfamily
AW03_RS08895	COG0612	Peptidase, M16
AW03_RS08900	COG0612	Peptidase, M16
AW03_RS08905	COG0300	oxidoreductase activity
AW03_RS08920	COG1426	Protein conserved in bacteria
AW03_RS08925	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AW03_RS08930	COG1058	Belongs to the CinA family
AW03_RS08930	COG1546	Belongs to the CinA family
AW03_RS08935	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AW03_RS08940	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AW03_RS08945	COG1418	mRNA catabolic process
AW03_RS08950	COG1692	metallophosphoesterase
AW03_RS08955	COG2359	stage V sporulation protein S
AW03_RS08960	COG1063	alcohol dehydrogenase
AW03_RS08965	COG0156	8-amino-7-oxononanoate synthase activity
AW03_RS08970	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AW03_RS08975	COG4550	Control of competence regulator ComK, YlbF/YmcA
AW03_RS08985	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AW03_RS08990	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AW03_RS09005	COG3226	Transcriptional regulator
AW03_RS09010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW03_RS09020	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AW03_RS09025	COG3321	synthase
AW03_RS09030	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AW03_RS09030	COG2070	2-Nitropropane dioxygenase
AW03_RS09035	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AW03_RS09040	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AW03_RS09045	COG3425	synthase
AW03_RS09050	COG1024	Enoyl-CoA hydratase
AW03_RS09055	COG1024	Enoyl-CoA hydratase
AW03_RS09060	COG3321	synthase
AW03_RS09060	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_RS09060	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW03_RS09060	COG0318	PFAM AMP-dependent synthetase and ligase
AW03_RS09060	COG0300	oxidoreductase activity
AW03_RS09065	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AW03_RS09065	COG0300	oxidoreductase activity
AW03_RS09065	COG3321	synthase
AW03_RS09065	COG4221	oxidoreductase activity
AW03_RS09070	COG3321	synthase
AW03_RS09070	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AW03_RS09070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AW03_RS09070	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_RS09070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW03_RS09075	COG4221	oxidoreductase activity
AW03_RS09075	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_RS09075	COG3321	synthase
AW03_RS09075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW03_RS09080	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AW03_RS09080	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AW03_RS09080	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AW03_RS09080	COG3321	synthase
AW03_RS09085	COG2124	cytochrome p450
AW03_RS09095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW03_RS09100	COG1404	Belongs to the peptidase S8 family
AW03_RS09110	COG4195	phage-related replication protein
AW03_RS09115	COG1764	response to oxidative stress
AW03_RS09120	COG2076	Multidrug Resistance protein
AW03_RS09125	COG2076	Multidrug Resistance protein
AW03_RS09140	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AW03_RS09145	COG1923	regulation of RNA biosynthetic process
AW03_RS09160	COG1780	Probably involved in ribonucleotide reductase function
AW03_RS09165	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AW03_RS09170	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AW03_RS09175	COG4112	unkown
AW03_RS09180	COG0860	N-Acetylmuramoyl-L-alanine amidase
AW03_RS09185	COG0464	growth
AW03_RS09195	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AW03_RS09200	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
AW03_RS09205	COG0789	Transcriptional regulator
AW03_RS09210	COG0174	glutamine synthetase
AW03_RS09260	COG4282	regulation of fungal-type cell wall biogenesis
AW03_RS09270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW03_RS09285	COG3655	Transcriptional regulator
AW03_RS09315	COG2211	Major facilitator Superfamily
AW03_RS09320	COG3507	Belongs to the glycosyl hydrolase 43 family
AW03_RS09325	COG1940	carbohydrate kinase activity
AW03_RS09330	COG2115	Belongs to the xylose isomerase family
AW03_RS09335	COG1070	Carbohydrate kinase
AW03_RS09340	COG1525	nuclease
AW03_RS09345	COG2814	Major facilitator Superfamily
AW03_RS09350	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AW03_RS09360	COG0756	dUTP diphosphatase activity
AW03_RS09370	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AW03_RS09400	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AW03_RS09415	COG3832	glyoxalase III activity
AW03_RS09430	COG0697	spore germination
AW03_RS09435	COG0531	amino acid
AW03_RS09465	COG4195	phage-related replication protein
AW03_RS09475	COG0346	lactoylglutathione lyase activity
AW03_RS09485	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AW03_RS09490	COG1388	LysM domain
AW03_RS09495	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AW03_RS09500	COG4224	UPF0291 protein
AW03_RS09505	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AW03_RS09515	COG3763	UPF0154 protein
AW03_RS09525	COG0785	Cytochrome C biogenesis protein
AW03_RS09530	COG2201	protein-glutamate methylesterase activity
AW03_RS09535	COG4846	Membrane protein involved in cytochrome C biogenesis
AW03_RS09545	COG0071	Belongs to the small heat shock protein (HSP20) family
AW03_RS09560	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AW03_RS09565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW03_RS09585	COG0824	Thioesterase
AW03_RS09595	COG4841	protein insertion into membrane
AW03_RS09600	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AW03_RS09605	COG1832	CoA-binding protein
AW03_RS09610	COG0187	DNA topoisomerase II activity
AW03_RS09615	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AW03_RS09630	COG1115	amino acid carrier protein
AW03_RS09635	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AW03_RS09650	COG5520	Belongs to the glycosyl hydrolase 30 family
AW03_RS09655	COG3507	Belongs to the glycosyl hydrolase 43 family
AW03_RS09660	COG2246	polysaccharide biosynthetic process
AW03_RS09665	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AW03_RS09670	COG0586	Pfam SNARE associated Golgi protein
AW03_RS09675	COG2404	hydrolase activity, acting on ester bonds
AW03_RS09680	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AW03_RS09685	COG1024	Enoyl-CoA hydratase
AW03_RS09690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AW03_RS09695	COG0511	ligase activity, forming carbon-carbon bonds
AW03_RS09700	COG0439	Biotin carboxylase
AW03_RS09705	COG0318	PFAM AMP-dependent synthetase and ligase
AW03_RS09710	COG1960	acyl-CoA dehydrogenase activity
AW03_RS09725	COG1649	PFAM Uncharacterised BCR, COG1649
AW03_RS09735	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AW03_RS09735	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW03_RS09740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW03_RS09755	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW03_RS09760	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW03_RS09765	COG2027	D-alanyl-D-alanine carboxypeptidase
AW03_RS09770	COG2017	converts alpha-aldose to the beta-anomer
AW03_RS09775	COG0534	Mate efflux family protein
AW03_RS09790	COG0582	viral genome integration into host DNA
AW03_RS09795	COG0166	Belongs to the GPI family
AW03_RS09800	COG0405	Gamma-glutamyltransferase
AW03_RS09805	COG0583	DNA-binding transcription factor activity
AW03_RS09810	COG0604	alcohol dehydrogenase
AW03_RS09815	COG0493	'glutamate synthase
AW03_RS09820	COG0070	glutamate synthase
AW03_RS09820	COG0067	glutamate synthase
AW03_RS09820	COG0069	glutamate synthase activity
AW03_RS09825	COG0583	DNA-binding transcription factor activity
AW03_RS09830	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AW03_RS09835	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AW03_RS09845	COG0300	oxidoreductase activity
AW03_RS09850	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
AW03_RS09860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW03_RS09865	COG2814	Major facilitator Superfamily
AW03_RS09870	COG1070	Carbohydrate kinase
AW03_RS09875	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AW03_RS09880	COG0243	molybdopterin cofactor binding
AW03_RS09905	COG5278	phosphoserine phosphatase activity
AW03_RS09905	COG0840	transmembrane signaling receptor activity
AW03_RS09910	COG2368	4-hydroxyphenylacetate
AW03_RS09915	COG4305	rare lipoprotein A
AW03_RS09920	COG3619	membrane
AW03_RS09925	COG3866	Pectate lyase
AW03_RS09930	COG2135	peptidase activity
AW03_RS09940	COG2140	Oxalate decarboxylase
AW03_RS09960	COG2720	vancomycin resistance protein
AW03_RS09970	COG3655	Transcriptional regulator
AW03_RS09975	COG3739	integral membrane protein
AW03_RS09980	COG0583	DNA-binding transcription factor activity
AW03_RS09985	COG0697	spore germination
AW03_RS09995	COG0693	protein deglycase activity
AW03_RS10000	COG2367	Beta-lactamase
AW03_RS10020	COG3848	Pyruvate phosphate dikinase
AW03_RS10020	COG0574	Belongs to the PEP-utilizing enzyme family
AW03_RS10025	COG0726	polysaccharide deacetylase
AW03_RS10030	COG1793	dna ligase
AW03_RS10060	COG5444	nuclease activity
AW03_RS10065	COG4282	regulation of fungal-type cell wall biogenesis
AW03_RS10070	COG1231	oxidoreductase activity
AW03_RS10075	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AW03_RS10080	COG0662	Cupin 2, conserved barrel domain protein
AW03_RS10080	COG2207	Transcriptional regulator
AW03_RS10085	COG0456	acetyltransferase
AW03_RS10090	COG1309	transcriptional regulator
AW03_RS10095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW03_RS10100	COG3708	Transcriptional regulator
AW03_RS10105	COG2378	regulation of single-species biofilm formation
AW03_RS10115	COG0640	Transcriptional regulator
AW03_RS10120	COG0741	lytic transglycosylase activity
AW03_RS10125	COG2322	membrane
AW03_RS10140	COG1619	proteins homologs of microcin C7 resistance protein MccF
AW03_RS10145	COG3239	Fatty acid desaturase
AW03_RS10150	COG4585	Histidine kinase
AW03_RS10155	COG2197	response regulator
AW03_RS10160	COG3584	3D domain protein
AW03_RS10160	COG1388	LysM domain
AW03_RS10165	COG0514	ATP-dependent DNA helicase (RecQ)
AW03_RS10175	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AW03_RS10180	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AW03_RS10195	COG0071	Belongs to the small heat shock protein (HSP20) family
AW03_RS10220	COG1012	belongs to the aldehyde dehydrogenase family
AW03_RS10225	COG1657	PFAM Prenyltransferase squalene oxidase
AW03_RS10230	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AW03_RS10235	COG0733	neurotransmitter:sodium symporter activity
AW03_RS10240	COG0385	Bile acid
AW03_RS10245	COG0508	dehydrogenase complex catalyzes the overall conversion of
AW03_RS10250	COG0567	Dehydrogenase, E1 component
AW03_RS10255	COG4548	von Willebrand factor, type A
AW03_RS10260	COG0714	Associated with various cellular activities
AW03_RS10265	COG2032	superoxide dismutase activity
AW03_RS10270	COG1388	LysM domain
AW03_RS10270	COG0791	NLP P60 protein
AW03_RS10275	COG1819	glycosyl
AW03_RS10280	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AW03_RS10285	COG0534	Mate efflux family protein
AW03_RS10290	COG1366	Belongs to the anti-sigma-factor antagonist family
AW03_RS10295	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AW03_RS10300	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AW03_RS10310	COG2962	Rard protein
AW03_RS10325	COG2610	gluconate transmembrane transporter activity
AW03_RS10330	COG1942	4-Oxalocrotonate Tautomerase
AW03_RS10335	COG1733	regulation of RNA biosynthetic process
AW03_RS10340	COG0778	Nitroreductase
AW03_RS10345	COG0400	carboxylic ester hydrolase activity
AW03_RS10350	COG0346	lactoylglutathione lyase activity
AW03_RS10360	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AW03_RS10365	COG3409	Peptidoglycan-binding domain 1 protein
AW03_RS10365	COG0793	Belongs to the peptidase S41A family
AW03_RS10370	COG2226	methyltransferase
AW03_RS10380	COG1876	peptidase activity
AW03_RS10385	COG0813	purine-nucleoside phosphorylase activity
AW03_RS10400	COG0671	phosphoesterase, PA-phosphatase related
AW03_RS10425	COG4479	Belongs to the UPF0346 family
AW03_RS10435	COG1509	lysine 2,3-aminomutase activity
AW03_RS10440	COG0456	acetyltransferase
AW03_RS10445	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AW03_RS10450	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AW03_RS10455	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AW03_RS10460	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AW03_RS10475	COG0456	acetyltransferase
AW03_RS10480	COG0463	Glycosyl transferase, family 2
AW03_RS10495	COG4641	Protein conserved in bacteria
AW03_RS10500	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
AW03_RS10505	COG1086	Polysaccharide biosynthesis protein
AW03_RS10510	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AW03_RS10515	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AW03_RS10520	COG1846	Transcriptional regulator
AW03_RS10525	COG0534	Mate efflux family protein
AW03_RS10535	COG4698	Protein conserved in bacteria
AW03_RS10540	COG2755	lipolytic protein G-D-S-L family
AW03_RS10545	COG1999	signal sequence binding
AW03_RS10560	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AW03_RS10565	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AW03_RS10570	COG1272	protein, Hemolysin III
AW03_RS10575	COG0204	Acyl-transferase
AW03_RS10580	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AW03_RS10585	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AW03_RS10590	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AW03_RS10600	COG2521	methyltransferase
AW03_RS10600	COG2136	Putative SAM-dependent methyltransferase
AW03_RS10610	COG0129	dihydroxy-acid dehydratase activity
AW03_RS10620	COG1413	lyase activity
AW03_RS10625	COG1418	mRNA catabolic process
AW03_RS10630	COG0386	Belongs to the glutathione peroxidase family
AW03_RS10635	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AW03_RS10640	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AW03_RS10645	COG1278	Cold shock
AW03_RS10665	COG0328	RNA-DNA hybrid ribonuclease activity
AW03_RS10670	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AW03_RS10675	COG0328	RNA-DNA hybrid ribonuclease activity
AW03_RS10685	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AW03_RS10705	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AW03_RS10710	COG1755	Isoprenylcysteine carboxyl methyltransferase
AW03_RS10715	COG3424	synthase
AW03_RS10720	COG2233	PERMEase
AW03_RS10725	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AW03_RS10730	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AW03_RS10740	COG0800	Aldolase
AW03_RS10745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AW03_RS10750	COG1609	Transcriptional regulator
AW03_RS10755	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
AW03_RS10760	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_RS10765	COG1199	ATP-dependent helicase activity
AW03_RS10775	COG0116	Belongs to the methyltransferase superfamily
AW03_RS10785	COG4474	Belongs to the UPF0398 family
AW03_RS10795	COG3359	exonuclease
AW03_RS10800	COG1205	dead DEAH box helicase
AW03_RS10800	COG1111	helicase
AW03_RS10805	COG2190	(PTS) system
AW03_RS10810	COG0071	Belongs to the small heat shock protein (HSP20) family
AW03_RS10845	COG3331	DNA recombination
AW03_RS10850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AW03_RS10850	COG4499	WXG100 protein secretion system (Wss), protein YukC
AW03_RS10860	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AW03_RS10865	COG3935	DnaD domain protein
AW03_RS10870	COG0017	Asparaginyl-tRNA synthetase
AW03_RS10875	COG0436	Aminotransferase
AW03_RS10880	COG5353	protein conserved in bacteria
AW03_RS10890	COG1199	ATP-dependent helicase activity
AW03_RS10890	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AW03_RS10895	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AW03_RS10900	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AW03_RS10905	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AW03_RS10910	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AW03_RS10910	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AW03_RS10915	COG0617	tRNA 3'-terminal CCA addition
AW03_RS10920	COG0438	transferase activity, transferring glycosyl groups
AW03_RS10925	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AW03_RS10930	COG1803	Methylglyoxal synthase
AW03_RS10935	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AW03_RS10940	COG1694	Mazg nucleotide pyrophosphohydrolase
AW03_RS10945	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW03_RS10955	COG4347	Protein of unknown function (DUF1405)
AW03_RS10960	COG2010	Cytochrome c
AW03_RS10960	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AW03_RS10965	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AW03_RS10970	COG0723	plastoquinol--plastocyanin reductase activity
AW03_RS10980	COG5582	Belongs to the UPF0302 family
AW03_RS10985	COG0457	Tetratricopeptide repeat
AW03_RS10990	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AW03_RS10995	COG0287	Prephenate dehydrogenase
AW03_RS11000	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AW03_RS11005	COG0159	tryptophan synthase activity
AW03_RS11010	COG0133	tryptophan synthase activity
AW03_RS11015	COG0135	phosphoribosylanthranilate isomerase activity
AW03_RS11025	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AW03_RS11030	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AW03_RS11035	COG4401	Chorismate mutase type I
AW03_RS11040	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AW03_RS11045	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AW03_RS11050	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AW03_RS11060	COG0105	UTP biosynthetic process
AW03_RS11065	COG0142	geranyltranstransferase activity
AW03_RS11070	COG2226	methyltransferase
AW03_RS11075	COG0142	geranyltranstransferase activity
AW03_RS11085	COG0302	gtp cyclohydrolase
AW03_RS11090	COG0776	regulation of translation
AW03_RS11095	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AW03_RS11110	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AW03_RS11115	COG1160	GTP binding
AW03_RS11140	COG1304	FMN binding
AW03_RS11145	COG0539	negative regulation of cytoplasmic translation
AW03_RS11150	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AW03_RS11160	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
AW03_RS11165	COG2959	enzyme of heme biosynthesis
AW03_RS11170	COG3773	Cell wall hydrolase
AW03_RS11170	COG3409	Peptidoglycan-binding domain 1 protein
AW03_RS11175	COG2339	peptidase activity
AW03_RS11180	COG0492	ferredoxin-NADP+ reductase activity
AW03_RS11185	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AW03_RS11190	COG4862	establishment of competence for transformation
AW03_RS11195	COG1408	metallophosphoesterase
AW03_RS11205	COG1388	LysM domain
AW03_RS11210	COG1266	CAAX protease self-immunity
AW03_RS11215	COG0514	ATP-dependent DNA helicase (RecQ)
AW03_RS11220	COG4955	Helix-turn-helix domain
AW03_RS11225	COG1141	Ferredoxin
AW03_RS11230	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AW03_RS11240	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AW03_RS11245	COG0710	3-dehydroquinate dehydratase activity
AW03_RS11255	COG1595	DNA-templated transcription, initiation
AW03_RS11260	COG5002	protein histidine kinase activity
AW03_RS11265	COG0745	RESPONSE REGULATOR receiver
AW03_RS11270	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AW03_RS11275	COG1333	cytochrome c biogenesis protein
AW03_RS11280	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW03_RS11285	COG1187	pseudouridine synthase activity
AW03_RS11290	COG0700	Nucleoside recognition
AW03_RS11295	COG2715	membrane protein required for spore maturation
AW03_RS11300	COG1686	Belongs to the peptidase S11 family
AW03_RS11310	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AW03_RS11315	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AW03_RS11320	COG1547	Domain of unknown function (DUF309)
AW03_RS11325	COG0456	acetyltransferase
AW03_RS11330	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AW03_RS11335	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AW03_RS11335	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AW03_RS11340	COG0307	riboflavin synthase, alpha
AW03_RS11345	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AW03_RS11345	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AW03_RS11355	COG0681	Belongs to the peptidase S26 family
AW03_RS11360	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
AW03_RS11370	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AW03_RS11375	COG4086	secreted protein
AW03_RS11380	COG0019	diaminopimelate decarboxylase activity
AW03_RS11385	COG0697	spore germination
AW03_RS11400	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AW03_RS11420	COG1191	sigma factor activity
AW03_RS11425	COG2172	sigma factor antagonist activity
AW03_RS11430	COG1366	Belongs to the anti-sigma-factor antagonist family
AW03_RS11435	COG1686	Belongs to the peptidase S11 family
AW03_RS11440	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AW03_RS11445	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AW03_RS11450	COG4974	Belongs to the 'phage' integrase family
AW03_RS11460	COG0735	belongs to the Fur family
AW03_RS11465	COG1300	Membrane
AW03_RS11475	COG0281	malic enzyme
AW03_RS11480	COG1757	Na H antiporter
AW03_RS11485	COG1027	Aspartate ammonia-lyase
AW03_RS11490	COG0252	asparaginase activity
AW03_RS11495	COG1396	sequence-specific DNA binding
AW03_RS11500	COG1379	DNA repair
AW03_RS11505	COG0494	nUDIX hydrolase
AW03_RS11515	COG0667	Aldo Keto reductase
AW03_RS11525	COG1073	alpha beta
AW03_RS11535	COG4918	Iron-sulphur cluster biosynthesis
AW03_RS11540	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AW03_RS11540	COG0456	acetyltransferase
AW03_RS11545	COG2329	Antibiotic biosynthesis monooxygenase
AW03_RS11550	COG0456	acetyltransferase
AW03_RS11560	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AW03_RS11570	COG2211	Major facilitator Superfamily
AW03_RS11580	COG0346	lactoylglutathione lyase activity
AW03_RS11585	COG1072	(Pantothenic acid kinase))
AW03_RS11590	COG3048	D-serine ammonia-lyase activity
AW03_RS11595	COG0300	oxidoreductase activity
AW03_RS11600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW03_RS11605	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AW03_RS11610	COG4187	Peptidase family M20/M25/M40
AW03_RS11615	COG1902	pentaerythritol trinitrate reductase activity
AW03_RS11620	COG0596	Alpha beta hydrolase
AW03_RS11630	COG1234	tRNA 3'-trailer cleavage
AW03_RS11635	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AW03_RS11640	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AW03_RS11645	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AW03_RS11655	COG0706	membrane insertase activity
AW03_RS11660	COG3361	conserved protein (COG2071)
AW03_RS11665	COG2195	Cleaves the N-terminal amino acid of tripeptides
AW03_RS11670	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AW03_RS11675	COG0346	lactoylglutathione lyase activity
AW03_RS11685	COG1376	ErfK ybiS ycfS ynhG family protein
AW03_RS11690	COG4129	membrane
AW03_RS11695	COG1126	abc transporter atp-binding protein
AW03_RS11700	COG0765	amino acid transport
AW03_RS11705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW03_RS11715	COG1597	lipid kinase activity
AW03_RS11720	COG2814	Major facilitator Superfamily
AW03_RS11725	COG0789	Transcriptional regulator
AW03_RS11725	COG4978	Transcriptional regulator
AW03_RS11730	COG0508	dehydrogenase complex catalyzes the overall conversion of
AW03_RS11735	COG0022	dehydrogenase e1 component
AW03_RS11740	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AW03_RS11745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AW03_RS11750	COG3426	butyrate kinase activity
AW03_RS11755	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AW03_RS11760	COG0280	phosphate acetyltransferase
AW03_RS11765	COG3829	transcription factor binding
AW03_RS11765	COG3290	protein histidine kinase activity
AW03_RS11775	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AW03_RS11780	COG2079	MmgE PrpD family protein
AW03_RS11785	COG0372	Belongs to the citrate synthase family
AW03_RS11790	COG1960	acyl-CoA dehydrogenase activity
AW03_RS11795	COG1250	3-hydroxyacyl-CoA dehydrogenase
AW03_RS11800	COG0183	Belongs to the thiolase family
AW03_RS11805	COG0584	glycerophosphoryl diester phosphodiesterase
AW03_RS11810	COG0860	N-Acetylmuramoyl-L-alanine amidase
AW03_RS11825	COG1902	pentaerythritol trinitrate reductase activity
AW03_RS11835	COG0745	RESPONSE REGULATOR receiver
AW03_RS11845	COG0750	zinc metalloprotease
AW03_RS11850	COG0497	DNA recombination
AW03_RS11855	COG1438	arginine binding
AW03_RS11860	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AW03_RS11865	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AW03_RS11870	COG0142	geranyltranstransferase activity
AW03_RS11875	COG1722	exodeoxyribonuclease VII activity
AW03_RS11880	COG1570	exodeoxyribonuclease VII activity
AW03_RS11885	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AW03_RS11890	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AW03_RS11895	COG1302	Protein conserved in bacteria
AW03_RS11900	COG0439	Biotin carboxylase
AW03_RS11905	COG0511	ligase activity, forming carbon-carbon bonds
AW03_RS11945	COG3854	ATPases associated with a variety of cellular activities
AW03_RS11955	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AW03_RS11960	COG0006	proline dipeptidase activity
AW03_RS11965	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AW03_RS11975	COG3872	metal-dependent enzyme
AW03_RS11985	COG1752	Esterase of the alpha-beta hydrolase superfamily
AW03_RS11990	COG1321	iron dependent repressor
AW03_RS11995	COG0095	Lipoate-protein ligase
AW03_RS12000	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AW03_RS12005	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AW03_RS12010	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AW03_RS12015	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AW03_RS12020	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AW03_RS12035	COG1396	sequence-specific DNA binding
AW03_RS12045	COG0681	Belongs to the peptidase S26 family
AW03_RS12070	COG4940	Competence protein ComGF
AW03_RS12080	COG4970	Tfp pilus assembly protein FimT
AW03_RS12085	COG4537	Required for transformation and DNA binding
AW03_RS12090	COG1459	type II secretion system
AW03_RS12095	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AW03_RS12105	COG0598	Magnesium transport protein CorA
AW03_RS12110	COG1253	flavin adenine dinucleotide binding
AW03_RS12115	COG1366	Belongs to the anti-sigma-factor antagonist family
AW03_RS12125	COG1393	Belongs to the ArsC family
AW03_RS12135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW03_RS12145	COG0011	TIGRFAM Protein of
AW03_RS12155	COG2866	Carboxypeptidase
AW03_RS12160	COG1368	sulfuric ester hydrolase activity
AW03_RS12165	COG1940	carbohydrate kinase activity
AW03_RS12170	COG4483	Protein conserved in bacteria
AW03_RS12175	COG0705	Rhomboid family
AW03_RS12175	COG0457	Tetratricopeptide repeat
AW03_RS12185	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AW03_RS12195	COG0438	transferase activity, transferring glycosyl groups
AW03_RS12210	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AW03_RS12215	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AW03_RS12220	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AW03_RS12225	COG0581	inorganic phosphate transmembrane transporter activity
AW03_RS12230	COG0573	inorganic phosphate transmembrane transporter activity
AW03_RS12235	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AW03_RS12240	COG0768	penicillin binding
AW03_RS12245	COG0477	Major facilitator Superfamily
AW03_RS12250	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AW03_RS12255	COG2839	Protein conserved in bacteria
AW03_RS12260	COG5521	maltodextrose utilization protein MalA
AW03_RS12265	COG1388	LysM domain
AW03_RS12270	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AW03_RS12275	COG4709	membrane
AW03_RS12280	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
AW03_RS12285	COG0735	belongs to the Fur family
AW03_RS12290	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW03_RS12300	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AW03_RS12305	COG0513	Belongs to the DEAD box helicase family
AW03_RS12315	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AW03_RS12320	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AW03_RS12325	COG2384	SAM-dependent methyltransferase
AW03_RS12330	COG2010	Cytochrome c
AW03_RS12335	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AW03_RS12340	COG0358	DNA primase activity
AW03_RS12345	COG1671	Belongs to the UPF0178 family
AW03_RS12350	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AW03_RS12355	COG0517	IMP dehydrogenase activity
AW03_RS12360	COG0751	glycine-tRNA ligase activity
AW03_RS12365	COG0752	glycyl-tRNA synthetase alpha subunit
AW03_RS12370	COG1381	Involved in DNA repair and RecF pathway recombination
AW03_RS12380	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AW03_RS12385	COG0295	cytidine deaminase activity
AW03_RS12390	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AW03_RS12395	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AW03_RS12400	COG1480	7TM receptor with intracellular HD hydrolase
AW03_RS12410	COG1702	phosphate starvation-inducible protein PhoH
AW03_RS12415	COG0561	phosphatase activity
AW03_RS12430	COG4864	UPF0365 protein
AW03_RS12435	COG1030	water channel activity
AW03_RS12440	COG1610	YqeY-like protein
AW03_RS12450	COG1283	sodium-dependent phosphate transmembrane transporter activity
AW03_RS12455	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AW03_RS12460	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AW03_RS12465	COG2264	protein methyltransferase activity
AW03_RS12470	COG0484	heat shock protein binding
AW03_RS12475	COG0443	Heat shock 70 kDa protein
AW03_RS12480	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AW03_RS12485	COG1420	regulation of RNA biosynthetic process
AW03_RS12490	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AW03_RS12495	COG0481	GTPase activity
AW03_RS12505	COG0860	N-Acetylmuramoyl-L-alanine amidase
AW03_RS12510	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AW03_RS12515	COG0268	Binds directly to 16S ribosomal RNA
AW03_RS12520	COG1466	dna polymerase III delta subunit
AW03_RS12530	COG2333	competence protein COMEC
AW03_RS12530	COG0658	competence protein
AW03_RS12535	COG2131	deaminase
AW03_RS12540	COG1555	photosystem II stabilization
AW03_RS12540	COG1596	polysaccharide export
AW03_RS12545	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AW03_RS12550	COG2226	methyltransferase
AW03_RS12555	COG0799	negative regulation of ribosome biogenesis
AW03_RS12560	COG1713	HD superfamily hydrolase involved in NAD metabolism
AW03_RS12565	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AW03_RS12570	COG1534	Rna-binding protein
AW03_RS12575	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AW03_RS12580	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AW03_RS12585	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AW03_RS12600	COG2755	lipolytic protein G-D-S-L family
AW03_RS12605	COG3409	Peptidoglycan-binding domain 1 protein
AW03_RS12605	COG5632	N-Acetylmuramoyl-L-alanine amidase
AW03_RS12610	COG0398	Pfam SNARE associated Golgi protein
AW03_RS12615	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AW03_RS12625	COG3209	COG3209 Rhs family protein
AW03_RS12640	COG3223	Belongs to the PsiE family
AW03_RS12645	COG5002	protein histidine kinase activity
AW03_RS12645	COG0642	Histidine kinase
AW03_RS12650	COG0745	RESPONSE REGULATOR receiver
AW03_RS12655	COG2311	Membrane
AW03_RS12665	COG0454	-acetyltransferase
AW03_RS12670	COG1733	regulation of RNA biosynthetic process
AW03_RS12675	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_RS12700	COG3409	Peptidoglycan-binding domain 1 protein
AW03_RS12700	COG5632	N-Acetylmuramoyl-L-alanine amidase
AW03_RS12705	COG4824	toxin secretion phage lysis holin
AW03_RS12725	COG0563	adenylate kinase activity
AW03_RS12730	COG2856	Zn peptidase
AW03_RS12740	COG2249	NAD(P)H dehydrogenase (quinone) activity
AW03_RS12750	COG1846	Transcriptional regulator
AW03_RS12755	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AW03_RS12765	COG0457	Tetratricopeptide repeat
AW03_RS12770	COG5444	nuclease activity
AW03_RS12795	COG4978	Transcriptional regulator
AW03_RS12795	COG0789	Transcriptional regulator
AW03_RS12800	COG2814	Major facilitator Superfamily
AW03_RS12805	COG0456	acetyltransferase
AW03_RS12810	COG1253	flavin adenine dinucleotide binding
AW03_RS12820	COG0697	spore germination
AW03_RS12825	COG0583	DNA-binding transcription factor activity
AW03_RS12830	COG2072	flavoprotein involved in K transport
AW03_RS12835	COG1230	cation diffusion facilitator family transporter
AW03_RS12840	COG1942	4-Oxalocrotonate Tautomerase
AW03_RS12845	COG0583	DNA-binding transcription factor activity
AW03_RS12855	COG1114	Component of the transport system for branched-chain amino acids
AW03_RS12860	COG1687	branched-chain amino acid
AW03_RS12865	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AW03_RS12870	COG1522	sequence-specific DNA binding
AW03_RS12880	COG2124	cytochrome p450
AW03_RS12895	COG1335	isochorismatase
AW03_RS12905	COG2318	DinB family
AW03_RS12915	COG2070	2-Nitropropane dioxygenase
AW03_RS12920	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AW03_RS12935	COG3443	Belongs to the bacterial solute-binding protein 9 family
AW03_RS12940	COG1595	DNA-templated transcription, initiation
AW03_RS12945	COG0667	Aldo Keto reductase
AW03_RS12950	COG3409	Peptidoglycan-binding domain 1 protein
AW03_RS12955	COG5566	PFAM Mor transcription activator
AW03_RS12960	COG0596	Alpha beta hydrolase
AW03_RS12965	COG4991	sh3 domain protein
AW03_RS12970	COG4991	sh3 domain protein
AW03_RS12975	COG0346	lactoylglutathione lyase activity
AW03_RS12985	COG5577	PFAM Coat F domain
AW03_RS12990	COG1063	alcohol dehydrogenase
AW03_RS13000	COG5577	PFAM Coat F domain
AW03_RS13005	COG0789	Transcriptional regulator
AW03_RS13015	COG1064	alcohol dehydrogenase
AW03_RS13020	COG0693	protein deglycase activity
AW03_RS13025	COG1621	beta-fructofuranosidase activity
AW03_RS13030	COG3716	PTS system mannose fructose sorbose family IID component
AW03_RS13035	COG3715	PTS system
AW03_RS13040	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW03_RS13045	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW03_RS13050	COG3933	PFAM sigma-54 factor interaction domain-containing protein
AW03_RS13050	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AW03_RS13055	COG1113	amino acid transport
AW03_RS13060	COG1280	lysine exporter protein (LysE YggA)
AW03_RS13065	COG1378	Sugar-specific transcriptional regulator TrmB
AW03_RS13070	COG1595	DNA-templated transcription, initiation
AW03_RS13080	COG2755	lipolytic protein G-D-S-L family
AW03_RS13080	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AW03_RS13090	COG2124	cytochrome p450
AW03_RS13090	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AW03_RS13095	COG1309	transcriptional regulator
AW03_RS13100	COG2226	methyltransferase
AW03_RS13110	COG2116	formate transmembrane transporter activity
AW03_RS13115	COG5609	conserved protein (DUF2294)
AW03_RS13120	COG3383	formate dehydrogenase (NAD+) activity
AW03_RS13125	COG2427	Protein of unknown function (DUF1641)
AW03_RS13135	COG0626	cystathionine gamma-synthase activity
AW03_RS13140	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AW03_RS13145	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AW03_RS13150	COG2226	methyltransferase
AW03_RS13165	COG0768	penicillin binding
AW03_RS13170	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AW03_RS13175	COG0572	uridine kinase
AW03_RS13180	COG0826	peptidase U32
AW03_RS13185	COG0826	peptidase U32
AW03_RS13190	COG4122	O-methyltransferase activity
AW03_RS13195	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AW03_RS13200	COG3906	Belongs to the UPF0473 family
AW03_RS13205	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AW03_RS13210	COG4472	Bacterial protein of unknown function (DUF965)
AW03_RS13215	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AW03_RS13220	COG0628	permease
AW03_RS13225	COG1126	abc transporter atp-binding protein
AW03_RS13230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW03_RS13235	COG0765	amino acid transport
AW03_RS13240	COG0765	amino acid transport
AW03_RS13255	COG3881	PFAM PRC-barrel domain
AW03_RS13260	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AW03_RS13265	COG0457	Tetratricopeptide repeat
AW03_RS13270	COG0482	sulfurtransferase activity
AW03_RS13275	COG1104	cysteine desulfurase activity
AW03_RS13280	COG1959	2 iron, 2 sulfur cluster binding
AW03_RS13285	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AW03_RS13290	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AW03_RS13300	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AW03_RS13305	COG0124	histidyl-tRNA synthetase
AW03_RS13315	COG0860	N-Acetylmuramoyl-L-alanine amidase
AW03_RS13315	COG4991	sh3 domain protein
AW03_RS13315	COG3103	Sh3 type 3 domain protein
AW03_RS13320	COG1490	D-aminoacyl-tRNA deacylase activity
AW03_RS13325	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AW03_RS13330	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AW03_RS13335	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AW03_RS13335	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AW03_RS13340	COG5416	Lipopolysaccharide assembly protein A domain
AW03_RS13345	COG0490	domain, Protein
AW03_RS13350	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AW03_RS13350	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AW03_RS13360	COG2244	polysaccharide biosynthetic process
AW03_RS13365	COG2323	membrane
AW03_RS13375	COG1862	Preprotein translocase
AW03_RS13380	COG0343	queuine tRNA-ribosyltransferase activity
AW03_RS13385	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AW03_RS13395	COG2255	four-way junction helicase activity
AW03_RS13400	COG0632	four-way junction helicase activity
AW03_RS13410	COG2814	Major facilitator Superfamily
AW03_RS13415	COG0673	inositol 2-dehydrogenase activity
AW03_RS13420	COG2112	serine threonine protein kinase
AW03_RS13440	COG1115	amino acid carrier protein
AW03_RS13445	COG0217	transcriptional regulatory protein
AW03_RS13455	COG1388	LysM domain
AW03_RS13460	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AW03_RS13465	COG0157	Belongs to the NadC ModD family
AW03_RS13470	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AW03_RS13475	COG1104	cysteine desulfurase activity
AW03_RS13480	COG1827	regulation of RNA biosynthetic process
AW03_RS13485	COG0077	Prephenate dehydratase
AW03_RS13490	COG4492	Belongs to the UPF0735 family
AW03_RS13495	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AW03_RS13500	COG3290	protein histidine kinase activity
AW03_RS13510	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AW03_RS13515	COG2868	ribosomal protein
AW03_RS13520	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AW03_RS13525	COG1994	Peptidase M50
AW03_RS13530	COG0739	heme binding
AW03_RS13535	COG2894	cell division
AW03_RS13540	COG0850	regulation of cytokinetic process
AW03_RS13545	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AW03_RS13555	COG1077	Cell shape determining protein MreB Mrl
AW03_RS13560	COG2003	Belongs to the UPF0758 family
AW03_RS13565	COG0424	maF-like protein
AW03_RS13575	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AW03_RS13580	COG0285	dihydrofolate synthase activity
AW03_RS13585	COG0525	valine-tRNA ligase activity
AW03_RS13595	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AW03_RS13600	COG1388	LysM domain
AW03_RS13605	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AW03_RS13610	COG0113	porphobilinogen synthase activity
AW03_RS13615	COG1587	Uroporphyrinogen-III synthase
AW03_RS13620	COG0181	hydroxymethylbilane synthase activity
AW03_RS13625	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AW03_RS13630	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AW03_RS13640	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AW03_RS13645	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AW03_RS13650	COG0470	DNA polymerase III
AW03_RS13650	COG1067	ATP-dependent peptidase activity
AW03_RS13655	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AW03_RS13660	COG0544	peptidyl-prolyl cis-trans isomerase activity
AW03_RS13665	COG1477	protein flavinylation
AW03_RS13665	COG0457	Tetratricopeptide repeat
AW03_RS13670	COG0066	3-isopropylmalate dehydratase activity
AW03_RS13675	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AW03_RS13680	COG0473	3-isopropylmalate dehydrogenase activity
AW03_RS13685	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AW03_RS13690	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AW03_RS13695	COG0440	acetolactate synthase activity
AW03_RS13700	COG0028	Belongs to the TPP enzyme family
AW03_RS13710	COG0454	-acetyltransferase
AW03_RS13720	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
AW03_RS13730	COG0622	Phosphoesterase
AW03_RS13735	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AW03_RS13740	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AW03_RS13745	COG5401	PFAM Sporulation and spore germination
AW03_RS13750	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AW03_RS13755	COG1846	Transcriptional regulator
AW03_RS13760	COG2197	response regulator
AW03_RS13765	COG0824	Thioesterase
AW03_RS13770	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AW03_RS13775	COG1053	succinate dehydrogenase
AW03_RS13780	COG2009	succinate dehydrogenase
AW03_RS13790	COG1719	4-vinyl reductase, 4VR
AW03_RS13795	COG0527	aspartate kinase activity
AW03_RS13800	COG0322	excinuclease ABC activity
AW03_RS13805	COG3118	belongs to the thioredoxin family
AW03_RS13810	COG3534	alpha-L-arabinofuranosidase
AW03_RS13815	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AW03_RS13820	COG2086	electron transfer activity
AW03_RS13825	COG1024	Enoyl-CoA hydratase
AW03_RS13830	COG1309	transcriptional regulator
AW03_RS13835	COG0318	PFAM AMP-dependent synthetase and ligase
AW03_RS13840	COG3766	membrane
AW03_RS13845	COG1193	negative regulation of DNA recombination
AW03_RS13850	COG1796	DNA polymerase
AW03_RS13850	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AW03_RS13855	COG1286	toxin biosynthetic process
AW03_RS13860	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AW03_RS13865	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AW03_RS13870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AW03_RS13870	COG0072	phenylalanine-tRNA ligase activity
AW03_RS13875	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AW03_RS13885	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AW03_RS13895	COG3835	regulator
AW03_RS13900	COG0277	FAD linked oxidase domain protein
AW03_RS13905	COG0247	lactate metabolic process
AW03_RS13910	COG0346	lactoylglutathione lyase activity
AW03_RS13915	COG1966	Carbon starvation protein
AW03_RS13920	COG3534	alpha-L-arabinofuranosidase
AW03_RS13925	COG0395	ABC-type sugar transport system, permease component
AW03_RS13930	COG1175	transmembrane transport
AW03_RS13935	COG1653	transport
AW03_RS13940	COG0371	Dehydrogenase
AW03_RS13945	COG0647	UMP catabolic process
AW03_RS13950	COG0235	Class ii aldolase
AW03_RS13955	COG1069	ribulokinase activity
AW03_RS13960	COG2160	L-arabinose isomerase activity
AW03_RS13965	COG3507	Belongs to the glycosyl hydrolase 43 family
AW03_RS13970	COG1363	Peptidase, m42
AW03_RS13980	COG3326	Membrane
AW03_RS13985	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AW03_RS13990	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AW03_RS13995	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AW03_RS14005	COG1346	cytolysis
AW03_RS14010	COG1380	Effector of murein hydrolase LrgA
AW03_RS14015	COG3279	Response regulator of the LytR AlgR family
AW03_RS14020	COG3275	phosphorelay sensor kinase activity
AW03_RS14025	COG1011	Hydrolase
AW03_RS14030	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AW03_RS14040	COG0398	Pfam SNARE associated Golgi protein
AW03_RS14045	COG1484	DNA-dependent DNA replication
AW03_RS14050	COG3611	Membrane attachment protein
AW03_RS14055	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AW03_RS14060	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AW03_RS14065	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AW03_RS14070	COG1733	regulation of RNA biosynthetic process
AW03_RS14075	COG2814	Major facilitator Superfamily
AW03_RS14080	COG0656	L-ascorbic acid biosynthetic process
AW03_RS14085	COG0237	dephospho-CoA kinase activity
AW03_RS14100	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AW03_RS14105	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AW03_RS14105	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AW03_RS14110	COG5002	protein histidine kinase activity
AW03_RS14115	COG0745	RESPONSE REGULATOR receiver
AW03_RS14120	COG0039	L-malate dehydrogenase activity
AW03_RS14125	COG0538	isocitrate dehydrogenase activity
AW03_RS14130	COG0372	Belongs to the citrate synthase family
AW03_RS14135	COG2707	UPF0756 membrane protein
AW03_RS14140	COG0628	permease
AW03_RS14145	COG3030	protein affecting phage T7 exclusion by the F plasmid
AW03_RS14150	COG0469	pyruvate kinase activity
AW03_RS14155	COG0205	6-phosphofructokinase activity
AW03_RS14160	COG0825	malonyl-CoA metabolic process
AW03_RS14165	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AW03_RS14170	COG0281	malic enzyme
AW03_RS14175	COG0587	DNA-directed DNA polymerase activity
AW03_RS14195	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AW03_RS14205	COG4109	DRTGG domain
AW03_RS14215	COG0730	response to heat
AW03_RS14220	COG1473	amidohydrolase
AW03_RS14225	COG0196	riboflavin kinase activity
AW03_RS14230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AW03_RS14235	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AW03_RS14240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AW03_RS14245	COG1126	abc transporter atp-binding protein
AW03_RS14250	COG0765	amino acid transport
AW03_RS14255	COG0765	amino acid transport
AW03_RS14260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW03_RS14265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW03_RS14270	COG0454	-acetyltransferase
AW03_RS14275	COG0583	DNA-binding transcription factor activity
AW03_RS14280	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AW03_RS14285	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_RS14295	COG0165	Argininosuccinate lyase
AW03_RS14300	COG0137	argininosuccinate synthase activity
AW03_RS14305	COG0521	Mo-molybdopterin cofactor biosynthetic process
AW03_RS14310	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AW03_RS14315	COG0827	DNA restriction-modification system
AW03_RS14320	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AW03_RS14325	COG3874	Sporulation protein YtfJ
AW03_RS14335	COG1714	RDD family
AW03_RS14340	COG0616	signal peptide processing
AW03_RS14345	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AW03_RS14350	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AW03_RS14355	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AW03_RS14365	COG0301	tRNA thio-modification
AW03_RS14370	COG1104	cysteine desulfurase activity
AW03_RS14375	COG1114	Component of the transport system for branched-chain amino acids
AW03_RS14380	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AW03_RS14385	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AW03_RS14390	COG1309	transcriptional regulator
AW03_RS14395	COG1956	GAF domain-containing protein
AW03_RS14400	COG2199	diguanylate cyclase activity
AW03_RS14400	COG2203	Gaf domain
AW03_RS14405	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AW03_RS14415	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AW03_RS14420	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AW03_RS14425	COG0454	-acetyltransferase
AW03_RS14430	COG0517	IMP dehydrogenase activity
AW03_RS14435	COG0123	including yeast histone deacetylase and acetoin utilization protein
AW03_RS14440	COG1360	Flagellar Motor Protein
AW03_RS14445	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AW03_RS14450	COG1609	Transcriptional regulator
AW03_RS14455	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AW03_RS14455	COG1605	Chorismate mutase
AW03_RS14460	COG3118	belongs to the thioredoxin family
AW03_RS14465	COG4980	gas vesicle protein
AW03_RS14470	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
AW03_RS14475	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AW03_RS14480	COG1674	ftsk spoiiie
AW03_RS14485	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AW03_RS14490	COG4848	Belongs to the UPF0354 family
AW03_RS14495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW03_RS14505	COG1363	Peptidase, m42
AW03_RS14510	COG5584	Small secreted protein
AW03_RS14515	COG0281	malic enzyme
AW03_RS14520	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW03_RS14525	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AW03_RS14535	COG0510	thiamine kinase activity
AW03_RS14540	COG1523	belongs to the glycosyl hydrolase 13 family
AW03_RS14545	COG1597	lipid kinase activity
AW03_RS14555	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AW03_RS14560	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AW03_RS14565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AW03_RS14570	COG2252	PERMEase
AW03_RS14575	COG4473	ABC transporter
AW03_RS14580	COG1131	(ABC) transporter
AW03_RS14585	COG1349	DNA-binding transcription factor activity
AW03_RS14590	COG1187	pseudouridine synthase activity
AW03_RS14595	COG2244	polysaccharide biosynthetic process
AW03_RS14600	COG2081	HI0933 family
AW03_RS14605	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AW03_RS14615	COG5578	integral membrane protein
AW03_RS14620	COG0673	inositol 2-dehydrogenase activity
AW03_RS14625	COG1653	transport
AW03_RS14630	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AW03_RS14635	COG4209	transmembrane transport
AW03_RS14640	COG2207	Transcriptional regulator
AW03_RS14645	COG1653	transport
AW03_RS14650	COG0395	ABC-type sugar transport system, permease component
AW03_RS14655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AW03_RS14660	COG2124	cytochrome p450
AW03_RS14665	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AW03_RS14675	COG0156	8-amino-7-oxononanoate synthase activity
AW03_RS14680	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AW03_RS14690	COG1073	alpha beta
AW03_RS14695	COG1609	Transcriptional regulator
AW03_RS14700	COG1653	transport
AW03_RS14705	COG1175	transmembrane transport
AW03_RS14710	COG0395	ABC-type sugar transport system, permease component
AW03_RS14715	COG1486	melibiose metabolic process
AW03_RS14720	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AW03_RS14725	COG0495	leucyl-tRNA aminoacylation
AW03_RS14735	COG2202	Pas domain
AW03_RS14735	COG1366	Belongs to the anti-sigma-factor antagonist family
AW03_RS14740	COG2814	Major facilitator Superfamily
AW03_RS14745	COG2433	Pfam Transposase IS66
AW03_RS14750	COG0577	efflux transmembrane transporter activity
AW03_RS14755	COG1136	(ABC) transporter
AW03_RS14760	COG2205	protein histidine kinase activity
AW03_RS14765	COG0745	RESPONSE REGULATOR receiver
AW03_RS14770	COG0577	efflux transmembrane transporter activity
AW03_RS14775	COG1136	(ABC) transporter
AW03_RS14790	COG1131	(ABC) transporter
AW03_RS14795	COG1725	Transcriptional regulator
AW03_RS14810	COG1242	4 iron, 4 sulfur cluster binding
AW03_RS14815	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AW03_RS14825	COG2267	carboxylic ester hydrolase activity
AW03_RS14830	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AW03_RS14835	COG1113	amino acid transport
AW03_RS14840	COG0367	asparagine synthase
AW03_RS14845	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AW03_RS14850	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AW03_RS14860	COG1506	peptidase
AW03_RS14865	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AW03_RS14870	COG1116	anion transmembrane transporter activity
AW03_RS14875	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AW03_RS14880	COG0494	nUDIX hydrolase
AW03_RS14885	COG4824	toxin secretion phage lysis holin
AW03_RS14890	COG0783	Belongs to the Dps family
AW03_RS14905	COG1854	S-ribosylhomocysteine lyase activity
AW03_RS14910	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AW03_RS14915	COG0288	reversible hydration of carbon dioxide
AW03_RS14920	COG0254	rRNA binding
AW03_RS14925	COG1271	oxidase subunit
AW03_RS14930	COG1294	oxidase, subunit
AW03_RS14940	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AW03_RS14945	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AW03_RS14945	COG1321	iron dependent repressor
AW03_RS14950	COG1121	(ABC) transporter
AW03_RS14955	COG0803	Belongs to the bacterial solute-binding protein 9 family
AW03_RS14960	COG4948	Mandelate Racemase Muconate Lactonizing
AW03_RS14965	COG0318	PFAM AMP-dependent synthetase and ligase
AW03_RS14970	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AW03_RS14975	COG0596	Alpha beta hydrolase
AW03_RS14980	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AW03_RS14985	COG1169	isochorismate synthase
AW03_RS14990	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AW03_RS14995	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AW03_RS15000	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AW03_RS15005	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AW03_RS15010	COG0438	transferase activity, transferring glycosyl groups
AW03_RS15020	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AW03_RS15025	COG0438	transferase activity, transferring glycosyl groups
AW03_RS15030	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AW03_RS15035	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
AW03_RS15040	COG0058	SHG alpha-glucan phosphorylase activity
AW03_RS15045	COG0297	glycogen (starch) synthase activity
AW03_RS15050	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AW03_RS15055	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AW03_RS15060	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AW03_RS15190	COG3859	Proton-coupled thiamine transporter YuaJ
AW03_RS15195	COG1247	-acetyltransferase
AW03_RS15200	COG1247	-acetyltransferase
AW03_RS15205	COG2268	Band 7 protein
AW03_RS15210	COG1585	Membrane protein implicated in regulation of membrane protease activity
AW03_RS15215	COG2318	DinB family
AW03_RS15225	COG1454	alcohol dehydrogenase
AW03_RS15230	COG1012	belongs to the aldehyde dehydrogenase family
AW03_RS15235	COG1510	regulation of RNA biosynthetic process
AW03_RS15245	COG0569	domain protein
AW03_RS15250	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AW03_RS15255	COG4682	membrane
AW03_RS15260	COG1705	Flagellar rod assembly protein muramidase FlgJ
AW03_RS15265	COG0477	Major facilitator Superfamily
AW03_RS15270	COG5553	Cysteine dioxygenase type I
AW03_RS15280	COG1968	undecaprenyl-diphosphatase activity
AW03_RS15285	COG0628	permease
AW03_RS15290	COG0673	inositol 2-dehydrogenase activity
AW03_RS15295	COG4806	L-rhamnose isomerase
AW03_RS15300	COG3254	rhamnose metabolic process
AW03_RS15305	COG1070	Carbohydrate kinase
AW03_RS15310	COG1349	DNA-binding transcription factor activity
AW03_RS15315	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_RS15315	COG3347	Dehydrogenase
AW03_RS15325	COG0840	transmembrane signaling receptor activity
AW03_RS15330	COG0840	transmembrane signaling receptor activity
AW03_RS15335	COG0840	transmembrane signaling receptor activity
AW03_RS15340	COG0840	transmembrane signaling receptor activity
AW03_RS15355	COG0432	Pfam Uncharacterised protein family UPF0047
AW03_RS15360	COG0366	Alpha amylase catalytic
AW03_RS15365	COG1253	flavin adenine dinucleotide binding
AW03_RS15370	COG2738	Putative neutral zinc metallopeptidase
AW03_RS15385	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AW03_RS15400	COG0166	Belongs to the GPI family
AW03_RS15405	COG1979	alcohol dehydrogenase
AW03_RS15410	COG1979	alcohol dehydrogenase
AW03_RS15415	COG2155	Conserved Protein
AW03_RS15420	COG1098	S1 RNA binding domain
AW03_RS15425	COG0436	Aminotransferase
AW03_RS15430	COG1522	sequence-specific DNA binding
AW03_RS15435	COG2267	carboxylic ester hydrolase activity
AW03_RS15445	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AW03_RS15450	COG2205	protein histidine kinase activity
AW03_RS15460	COG5018	Exonuclease
AW03_RS15470	COG2814	Major facilitator Superfamily
AW03_RS15475	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AW03_RS15480	COG3011	Protein conserved in bacteria
AW03_RS15490	COG3290	protein histidine kinase activity
AW03_RS15495	COG4565	transcriptional regulatory protein
AW03_RS15500	COG1744	ABC transporter substrate-binding protein PnrA-like
AW03_RS15505	COG3845	ABC transporter
AW03_RS15510	COG4603	Belongs to the binding-protein-dependent transport system permease family
AW03_RS15515	COG1079	Belongs to the binding-protein-dependent transport system permease family
AW03_RS15520	COG3493	citrate carrier protein
AW03_RS15530	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AW03_RS15530	COG2111	Na H antiporter
AW03_RS15535	COG2111	Na H antiporter
AW03_RS15540	COG1006	Multisubunit Na H antiporter MnhC subunit
AW03_RS15545	COG0651	ATP synthesis coupled electron transport
AW03_RS15550	COG1863	multisubunit Na H antiporter MnhE subunit
AW03_RS15555	COG2212	antiporter activity
AW03_RS15560	COG1320	monovalent cation:proton antiporter activity
AW03_RS15565	COG2050	protein possibly involved in aromatic compounds catabolism
AW03_RS15570	COG2197	response regulator
AW03_RS15575	COG4585	Histidine kinase
AW03_RS15585	COG0142	geranyltranstransferase activity
AW03_RS15600	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AW03_RS15605	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AW03_RS15610	COG1335	isochorismatase
AW03_RS15615	COG5506	Protein of unknown function (DUF1694)
AW03_RS15630	COG0628	permease
AW03_RS15645	COG1418	mRNA catabolic process
AW03_RS15650	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_RS15660	COG1511	domain protein
AW03_RS15665	COG0433	COG0433 Predicted ATPase
AW03_RS15665	COG1674	ftsk spoiiie
AW03_RS15670	COG4499	WXG100 protein secretion system (Wss), protein YukC
AW03_RS15675	COG5417	Belongs to the EsaB family
AW03_RS15680	COG4842	Belongs to the WXG100 family
AW03_RS15685	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AW03_RS15685	COG2508	Transcriptional regulator
AW03_RS15690	COG0686	Belongs to the AlaDH PNT family
AW03_RS15695	COG5634	Uncharacterized conserved protein (DUF2278)
AW03_RS15700	COG3251	PFAM MbtH domain protein
AW03_RS15705	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW03_RS15710	COG1535	isochorismatase
AW03_RS15710	COG3433	isochorismatase activity
AW03_RS15715	COG1021	2,3-dihydroxybenzoate-AMP ligase
AW03_RS15720	COG1169	isochorismate synthase
AW03_RS15725	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_RS15730	COG2819	hydrolase of the alpha beta superfamily
AW03_RS15735	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AW03_RS15740	COG1268	BioY protein
AW03_RS15745	COG2056	Na+-H+ antiporter family
AW03_RS15750	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AW03_RS15755	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
AW03_RS15760	COG3584	3D domain protein
AW03_RS15775	COG1252	NADH dehydrogenase
AW03_RS15780	COG0492	ferredoxin-NADP+ reductase activity
AW03_RS15790	COG0516	GMP reductase activity
AW03_RS15795	COG2808	Putative FMN-binding domain
AW03_RS15800	COG0456	acetyltransferase
AW03_RS15805	COG0316	Belongs to the HesB IscA family
AW03_RS15810	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AW03_RS15815	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AW03_RS15820	COG4844	belongs to the
AW03_RS15825	COG1252	NADH dehydrogenase
AW03_RS15830	COG4837	Protein of unknown function (DUF1462)
AW03_RS15835	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AW03_RS15840	COG0823	Involved in the tonB-independent uptake of proteins
AW03_RS15840	COG1506	peptidase
AW03_RS15840	COG4946	Tricorn protease homolog
AW03_RS15845	COG0083	homoserine kinase activity
AW03_RS15850	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AW03_RS15855	COG0460	homoserine dehydrogenase
AW03_RS15860	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AW03_RS15865	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AW03_RS15870	COG0647	UMP catabolic process
AW03_RS15875	COG2445	Protein of unknown function DUF86
AW03_RS15880	COG4470	Protein conserved in bacteria
AW03_RS15890	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AW03_RS15895	COG0739	heme binding
AW03_RS15905	COG3377	Domain of unknown function (DUF1805)
AW03_RS15910	COG0737	Belongs to the 5'-nucleotidase family
AW03_RS15915	COG0730	response to heat
AW03_RS15920	COG1801	Protein of unknown function DUF72
AW03_RS15930	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AW03_RS15935	COG2508	Transcriptional regulator
AW03_RS15940	COG2233	PERMEase
AW03_RS15945	COG2233	PERMEase
AW03_RS15950	COG3195	allantoin biosynthetic process
AW03_RS15950	COG3648	Uricase
AW03_RS15955	COG2351	hydroxyisourate hydrolase activity
AW03_RS15965	COG2080	2 iron, 2 sulfur cluster binding
AW03_RS15970	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AW03_RS15975	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AW03_RS15980	COG2068	MobA-Related Protein
AW03_RS15985	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AW03_RS15990	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AW03_RS15995	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AW03_RS16005	COG2356	endonuclease I
AW03_RS16010	COG3842	ATPase activity
AW03_RS16015	COG2188	Transcriptional regulator
AW03_RS16020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AW03_RS16025	COG0395	ABC-type sugar transport system, permease component
AW03_RS16030	COG1175	transmembrane transport
AW03_RS16035	COG1653	transport
AW03_RS16040	COG2222	sugar isomerase
AW03_RS16045	COG0322	excinuclease ABC activity
AW03_RS16050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AW03_RS16065	COG0346	lactoylglutathione lyase activity
AW03_RS16070	COG0640	Transcriptional regulator
AW03_RS16075	COG0719	Fe-S assembly protein
AW03_RS16080	COG0822	iron-sulfur transferase activity
AW03_RS16085	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AW03_RS16090	COG0719	Fe-S assembly protein
AW03_RS16095	COG0396	ATPase activity
AW03_RS16105	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AW03_RS16110	COG1464	Belongs to the NlpA lipoprotein family
AW03_RS16115	COG2011	ABC-type metal ion transport system permease component
AW03_RS16120	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AW03_RS16130	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW03_RS16135	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AW03_RS16145	COG0509	glycine decarboxylation via glycine cleavage system
AW03_RS16150	COG1393	Belongs to the ArsC family
AW03_RS16155	COG1960	acyl-CoA dehydrogenase activity
AW03_RS16160	COG0183	Belongs to the thiolase family
AW03_RS16165	COG1024	Enoyl-CoA hydratase
AW03_RS16165	COG1250	3-hydroxyacyl-CoA dehydrogenase
AW03_RS16175	COG0506	proline dehydrogenase activity
AW03_RS16185	COG5577	PFAM Coat F domain
AW03_RS16190	COG1846	Transcriptional regulator
AW03_RS16195	COG0477	Major facilitator Superfamily
AW03_RS16200	COG1942	4-Oxalocrotonate Tautomerase
AW03_RS16205	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_RS16210	COG0583	DNA-binding transcription factor activity
AW03_RS16220	COG1120	ATPase activity
AW03_RS16235	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_RS16240	COG0783	Belongs to the Dps family
AW03_RS16245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AW03_RS16250	COG0745	RESPONSE REGULATOR receiver
AW03_RS16255	COG2770	Histidine kinase
AW03_RS16255	COG2205	protein histidine kinase activity
AW03_RS16265	COG1309	transcriptional regulator
AW03_RS16270	COG0114	fumarate hydratase activity
AW03_RS16280	COG0697	spore germination
AW03_RS16285	COG0814	amino acid
AW03_RS16295	COG2197	response regulator
AW03_RS16300	COG4585	Histidine kinase
AW03_RS16305	COG4758	membrane
AW03_RS16310	COG3595	metallopeptidase activity
AW03_RS16315	COG1842	Phage shock protein A
AW03_RS16320	COG4758	membrane
AW03_RS16325	COG2814	Major facilitator Superfamily
AW03_RS16330	COG2096	Adenosyltransferase
AW03_RS16335	COG1120	ATPase activity
AW03_RS16340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW03_RS16345	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW03_RS16355	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_RS16360	COG3386	PFAM SMP-30 Gluconolaconase
AW03_RS16365	COG2205	protein histidine kinase activity
AW03_RS16370	COG0745	RESPONSE REGULATOR receiver
AW03_RS16380	COG1191	sigma factor activity
AW03_RS16390	COG2140	Oxalate decarboxylase
AW03_RS16400	COG0577	efflux transmembrane transporter activity
AW03_RS16405	COG1136	(ABC) transporter
AW03_RS16410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AW03_RS16415	COG1120	ATPase activity
AW03_RS16420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW03_RS16425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW03_RS16430	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW03_RS16435	COG0531	amino acid
AW03_RS16445	COG1988	membrane-bound metal-dependent
AW03_RS16450	COG1368	sulfuric ester hydrolase activity
AW03_RS16455	COG1910	domain protein
AW03_RS16460	COG0725	ABC transporter, periplasmic molybdate-binding protein
AW03_RS16465	COG4149	molybdate abc transporter
AW03_RS16470	COG0656	L-ascorbic acid biosynthetic process
AW03_RS16480	COG0025	NhaP-type Na H and K H
AW03_RS16485	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AW03_RS16490	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AW03_RS16495	COG3973	AAA domain
AW03_RS16505	COG2860	membrane
AW03_RS16510	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AW03_RS16515	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AW03_RS16520	COG2217	Heavy metal translocating P-type atpase
AW03_RS16525	COG2217	Heavy metal translocating P-type atpase
AW03_RS16530	COG2608	mercury ion transmembrane transporter activity
AW03_RS16535	COG1937	Protein conserved in bacteria
AW03_RS16540	COG0673	inositol 2-dehydrogenase activity
AW03_RS16545	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AW03_RS16550	COG1289	transmembrane transporter activity
AW03_RS16560	COG2076	Multidrug Resistance protein
AW03_RS16565	COG1309	transcriptional regulator
AW03_RS16570	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_RS16575	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AW03_RS16580	COG0557	exoribonuclease II activity
AW03_RS16585	COG1647	Serine aminopeptidase, S33
AW03_RS16590	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AW03_RS16595	COG0596	Alpha beta hydrolase
AW03_RS16600	COG1476	TRANSCRIPTIONal
AW03_RS16605	COG1396	sequence-specific DNA binding
AW03_RS16610	COG1396	sequence-specific DNA binding
AW03_RS16615	COG1733	regulation of RNA biosynthetic process
AW03_RS16640	COG1174	glycine betaine transport
AW03_RS16645	COG1732	Glycine betaine
AW03_RS16650	COG1174	glycine betaine transport
AW03_RS16655	COG0517	IMP dehydrogenase activity
AW03_RS16655	COG1125	glycine betaine transport
AW03_RS16660	COG1510	regulation of RNA biosynthetic process
AW03_RS16665	COG1174	glycine betaine transport
AW03_RS16670	COG1732	Glycine betaine
AW03_RS16675	COG1174	glycine betaine transport
AW03_RS16680	COG1125	glycine betaine transport
AW03_RS16680	COG0517	IMP dehydrogenase activity
AW03_RS16685	COG1510	regulation of RNA biosynthetic process
AW03_RS16690	COG2095	MarC family integral membrane protein
AW03_RS16700	COG3064	Membrane
AW03_RS16705	COG4640	response to antibiotic
AW03_RS16710	COG0456	acetyltransferase
AW03_RS16725	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AW03_RS16745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AW03_RS16750	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AW03_RS16760	COG2234	aminopeptidase activity
AW03_RS16765	COG0148	phosphopyruvate hydratase activity
AW03_RS16770	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AW03_RS16775	COG0149	triose-phosphate isomerase activity
AW03_RS16780	COG0126	phosphoglycerate kinase activity
AW03_RS16790	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AW03_RS16795	COG2390	Transcriptional regulator
AW03_RS16800	COG2814	Major facilitator Superfamily
AW03_RS16805	COG1609	Transcriptional regulator
AW03_RS16810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AW03_RS16815	COG0583	DNA-binding transcription factor activity
AW03_RS16820	COG0697	spore germination
AW03_RS16825	COG1113	amino acid transport
AW03_RS16830	COG3858	chitin binding
AW03_RS16835	COG1556	Lactate utilization protein
AW03_RS16840	COG1139	Iron-sulfur cluster binding protein
AW03_RS16845	COG0247	lactate metabolic process
AW03_RS16850	COG2197	response regulator
AW03_RS16855	COG4585	Histidine kinase
AW03_RS16860	COG0842	Transport permease protein
AW03_RS16865	COG1131	(ABC) transporter
AW03_RS16870	COG0596	Alpha beta hydrolase
AW03_RS16875	COG2208	phosphoserine phosphatase activity
AW03_RS16880	COG3867	Arabinogalactan endo-beta-1,4-galactanase
AW03_RS16885	COG1874	Beta-galactosidase
AW03_RS16890	COG3833	ABC-type maltose transport systems, permease component
AW03_RS16895	COG1175	transmembrane transport
AW03_RS16900	COG2182	Extracellular solute-binding protein
AW03_RS16905	COG1609	Transcriptional regulator
AW03_RS16910	COG2186	Transcriptional regulator
AW03_RS16915	COG1620	l-lactate permease
AW03_RS16920	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AW03_RS16930	COG5039	Polysaccharide pyruvyl transferase
AW03_RS16935	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AW03_RS16940	COG0110	maltose O-acetyltransferase activity
AW03_RS16945	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AW03_RS16950	COG2244	polysaccharide biosynthetic process
AW03_RS16955	COG1216	Glycosyl transferase, family 2
AW03_RS16960	COG5039	Polysaccharide pyruvyl transferase
AW03_RS16965	COG1216	Glycosyl transferase, family 2
AW03_RS16975	COG0438	transferase activity, transferring glycosyl groups
AW03_RS16980	COG1215	transferase activity, transferring glycosyl groups
AW03_RS16985	COG0438	transferase activity, transferring glycosyl groups
AW03_RS16990	COG1086	Polysaccharide biosynthesis protein
AW03_RS16995	COG0489	protein tyrosine kinase activity
AW03_RS17000	COG3944	biosynthesis protein
AW03_RS17005	COG1396	sequence-specific DNA binding
AW03_RS17010	COG2272	Belongs to the type-B carboxylesterase lipase family
AW03_RS17020	COG3479	Phenolic acid decarboxylase
AW03_RS17030	COG1794	racemase activity, acting on amino acids and derivatives
AW03_RS17035	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AW03_RS17045	COG1621	beta-fructofuranosidase activity
AW03_RS17050	COG1621	beta-fructofuranosidase activity
AW03_RS17055	COG0531	amino acid
AW03_RS17060	COG1309	transcriptional regulator
AW03_RS17065	COG2076	Multidrug Resistance protein
AW03_RS17070	COG2076	Multidrug Resistance protein
AW03_RS17115	COG0740	serine-type endopeptidase activity
AW03_RS17120	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AW03_RS17125	COG0366	Alpha amylase catalytic
AW03_RS17130	COG1554	hydrolase, family 65, central catalytic
AW03_RS17135	COG5521	maltodextrose utilization protein MalA
AW03_RS17140	COG3833	ABC-type maltose transport systems, permease component
AW03_RS17145	COG1175	transmembrane transport
AW03_RS17150	COG2182	Extracellular solute-binding protein
AW03_RS17155	COG0366	Alpha amylase catalytic
AW03_RS17160	COG1609	Transcriptional regulator
AW03_RS17165	COG1611	Belongs to the LOG family
AW03_RS17170	COG1694	Mazg nucleotide pyrophosphohydrolase
AW03_RS17175	COG0659	secondary active sulfate transmembrane transporter activity
AW03_RS17180	COG0288	reversible hydration of carbon dioxide
AW03_RS17185	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AW03_RS17190	COG0577	efflux transmembrane transporter activity
AW03_RS17195	COG1136	(ABC) transporter
AW03_RS17200	COG5002	protein histidine kinase activity
AW03_RS17205	COG0745	RESPONSE REGULATOR receiver
AW03_RS17215	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AW03_RS17220	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW03_RS17225	COG1481	regulation of sporulation
AW03_RS17230	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AW03_RS17235	COG1660	Displays ATPase and GTPase activities
AW03_RS17240	COG1051	belongs to the nudix hydrolase family
AW03_RS17245	COG0492	ferredoxin-NADP+ reductase activity
AW03_RS17250	COG3883	PFAM NLP P60 protein
AW03_RS17250	COG0791	NLP P60 protein
AW03_RS17255	COG0457	Tetratricopeptide repeat
AW03_RS17260	COG1132	(ABC) transporter
AW03_RS17280	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AW03_RS17280	COG0140	phosphoribosyl-ATP diphosphatase activity
AW03_RS17285	COG0107	imidazoleglycerol-phosphate synthase activity
AW03_RS17290	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AW03_RS17295	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AW03_RS17300	COG0131	Imidazoleglycerol-phosphate dehydratase
AW03_RS17305	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AW03_RS17310	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AW03_RS17315	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AW03_RS17320	COG4990	cell redox homeostasis
AW03_RS17325	COG5297	Belongs to the glycosyl hydrolase family 6
AW03_RS17330	COG0110	maltose O-acetyltransferase activity
AW03_RS17335	COG0546	phosphoglycolate phosphatase activity
AW03_RS17340	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AW03_RS17345	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AW03_RS17350	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AW03_RS17355	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AW03_RS17360	COG0363	glucosamine-6-phosphate deaminase activity
AW03_RS17365	COG2188	Transcriptional regulator
AW03_RS17370	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AW03_RS17375	COG1950	PFAM Membrane protein of
AW03_RS17380	COG1983	PspC domain protein
AW03_RS17385	COG3595	metallopeptidase activity
AW03_RS17400	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AW03_RS17405	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AW03_RS17410	COG0556	nucleotide-excision repair
AW03_RS17415	COG4897	Protein conserved in bacteria
AW03_RS17420	COG0574	Belongs to the PEP-utilizing enzyme family
AW03_RS17420	COG3848	Pyruvate phosphate dikinase
AW03_RS17425	COG1309	transcriptional regulator
AW03_RS17430	COG2814	Major facilitator Superfamily
AW03_RS17435	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AW03_RS17445	COG0793	Belongs to the peptidase S41A family
AW03_RS17445	COG3409	Peptidoglycan-binding domain 1 protein
AW03_RS17450	COG2177	Part of the ABC transporter FtsEX involved in
AW03_RS17455	COG2884	Cell division ATP-binding protein ftsE
AW03_RS17460	COG2010	Cytochrome c
AW03_RS17465	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW03_RS17470	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AW03_RS17475	COG0653	protein targeting
AW03_RS17480	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AW03_RS17495	COG1516	flagellar protein fliS
AW03_RS17500	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AW03_RS17505	COG1334	flagellar protein FlaG
AW03_RS17510	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AW03_RS17515	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AW03_RS17520	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
AW03_RS17530	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AW03_RS17535	COG1256	bacterial-type flagellum assembly
AW03_RS17535	COG4786	Flagellar basal body rod
AW03_RS17540	COG3418	PFAM FlgN family protein
AW03_RS17545	COG2747	anti-sigma28 factor FlgM
AW03_RS17555	COG1040	competence protein
AW03_RS17565	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AW03_RS17570	COG1307	EDD domain protein, DegV family
AW03_RS17575	COG2197	response regulator
AW03_RS17580	COG4585	Histidine kinase
AW03_RS17585	COG1739	Uncharacterized protein family UPF0029
AW03_RS17590	COG1316	TRANSCRIPTIONal
AW03_RS17595	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AW03_RS17600	COG0438	transferase activity, transferring glycosyl groups
AW03_RS17605	COG1215	transferase activity, transferring glycosyl groups
AW03_RS17610	COG3206	protein involved in exopolysaccharide biosynthesis
AW03_RS17615	COG3307	-O-antigen
AW03_RS17620	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AW03_RS17625	COG0297	glycogen (starch) synthase activity
AW03_RS17625	COG0438	transferase activity, transferring glycosyl groups
AW03_RS17630	COG2244	polysaccharide biosynthetic process
AW03_RS17645	COG2247	cell wall binding repeat
AW03_RS17645	COG0860	N-Acetylmuramoyl-L-alanine amidase
AW03_RS17650	COG2385	sporulation resulting in formation of a cellular spore
AW03_RS17650	COG2247	cell wall binding repeat
AW03_RS17660	COG1316	TRANSCRIPTIONal
AW03_RS17665	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AW03_RS17685	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AW03_RS17690	COG1134	teichoic acid transport
AW03_RS17695	COG1682	transport, permease protein
AW03_RS17715	COG0463	Glycosyl transferase, family 2
AW03_RS17760	COG4193	domain, Protein
AW03_RS17765	COG1482	cell wall glycoprotein biosynthetic process
AW03_RS17775	COG0697	spore germination
AW03_RS17780	COG0814	amino acid
AW03_RS17790	COG2814	Major facilitator Superfamily
AW03_RS17795	COG1316	TRANSCRIPTIONal
AW03_RS17800	COG0561	phosphatase activity
AW03_RS17805	COG0791	NLP P60 protein
AW03_RS17815	COG2843	Capsule synthesis protein
AW03_RS17825	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AW03_RS17830	COG1609	Transcriptional regulator
AW03_RS17835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AW03_RS17840	COG1869	D-ribose catabolic process
AW03_RS17845	COG1129	ABC transporter
AW03_RS17850	COG1172	Belongs to the binding-protein-dependent transport system permease family
AW03_RS17855	COG1879	ABC-type sugar transport system periplasmic component
AW03_RS17860	COG3103	Sh3 type 3 domain protein
AW03_RS17870	COG2249	NAD(P)H dehydrogenase (quinone) activity
AW03_RS17875	COG3527	Alpha-acetolactate decarboxylase
AW03_RS17880	COG0028	Belongs to the TPP enzyme family
AW03_RS17885	COG0583	DNA-binding transcription factor activity
AW03_RS17890	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AW03_RS17905	COG5337	Spore coat protein CotH
AW03_RS17915	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AW03_RS17925	COG0405	Gamma-glutamyltransferase
AW03_RS17930	COG1522	sequence-specific DNA binding
AW03_RS17935	COG2059	Chromate
AW03_RS17940	COG2059	Chromate
AW03_RS17955	COG5444	nuclease activity
AW03_RS17970	COG5444	nuclease activity
AW03_RS17985	COG3878	Protein conserved in bacteria
AW03_RS17990	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AW03_RS17995	COG4464	protein tyrosine phosphatase activity
AW03_RS18000	COG0489	protein tyrosine kinase activity
AW03_RS18005	COG3944	biosynthesis protein
AW03_RS18015	COG4715	Zinc finger, swim domain protein
AW03_RS18020	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AW03_RS18025	COG0561	phosphatase activity
AW03_RS18030	COG1349	DNA-binding transcription factor activity
AW03_RS18035	COG0629	single-stranded DNA binding
AW03_RS18050	COG3764	Sortase (surface protein transpeptidase)
AW03_RS18060	COG3279	Response regulator of the LytR AlgR family
AW03_RS18065	COG2972	Histidine kinase
AW03_RS18065	COG0745	RESPONSE REGULATOR receiver
AW03_RS18070	COG1970	mechanosensitive ion channel activity
AW03_RS18075	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AW03_RS18080	COG0457	Tetratricopeptide repeat
AW03_RS18085	COG4786	Flagellar basal body rod
AW03_RS18090	COG4786	Flagellar basal body rod
AW03_RS18095	COG1077	Cell shape determining protein MreB Mrl
AW03_RS18100	COG1609	Transcriptional regulator
AW03_RS18105	COG1846	Transcriptional regulator
AW03_RS18110	COG2814	Major facilitator Superfamily
AW03_RS18115	COG3420	alginic acid biosynthetic process
AW03_RS18120	COG1953	Uracil, thiamine, allantoin
AW03_RS18125	COG0477	Major facilitator Superfamily
AW03_RS18130	COG1335	isochorismatase
AW03_RS18140	COG0004	ammonium transporteR
AW03_RS18145	COG0347	Belongs to the P(II) protein family
AW03_RS18150	COG0671	phosphoesterase, PA-phosphatase related
AW03_RS18160	COG0739	heme binding
AW03_RS18165	COG1247	-acetyltransferase
AW03_RS18175	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AW03_RS18185	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AW03_RS18190	COG0789	Transcriptional regulator
AW03_RS18200	COG2910	NAD(P)H-binding
AW03_RS18205	COG1959	2 iron, 2 sulfur cluster binding
AW03_RS18210	COG0804	urea catabolic process
AW03_RS18215	COG0832	Belongs to the urease beta subunit family
AW03_RS18220	COG0831	urea catabolic process
AW03_RS18235	COG3237	CsbD-like
AW03_RS18240	COG1994	Peptidase M50
AW03_RS18245	COG0457	Tetratricopeptide repeat
AW03_RS18250	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AW03_RS18255	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AW03_RS18265	COG2304	oxidoreductase activity
AW03_RS18275	COG2304	oxidoreductase activity
AW03_RS18280	COG2385	sporulation resulting in formation of a cellular spore
AW03_RS18285	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AW03_RS18295	COG4836	Membrane
AW03_RS18305	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AW03_RS18310	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AW03_RS18315	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AW03_RS18320	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AW03_RS18325	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AW03_RS18330	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AW03_RS18345	COG0356	it plays a direct role in the translocation of protons across the membrane
AW03_RS18355	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AW03_RS18360	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AW03_RS18365	COG4475	Protein of unknown function (DUF436)
AW03_RS18370	COG0698	ribose 5-phosphate isomerase
AW03_RS18375	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AW03_RS18380	COG1971	Probably functions as a manganese efflux pump
AW03_RS18385	COG0009	L-threonylcarbamoyladenylate synthase
AW03_RS18390	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AW03_RS18410	COG2890	protein-(glutamine-N5) methyltransferase activity
AW03_RS18415	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AW03_RS18420	COG0346	lactoylglutathione lyase activity
AW03_RS18425	COG0789	Transcriptional regulator
AW03_RS18430	COG0679	Auxin Efflux Carrier
AW03_RS18435	COG0281	malic enzyme
AW03_RS18440	COG1435	thymidine kinase activity
AW03_RS18450	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AW03_RS18460	COG1494	fructose-1,6-bisphosphatase
AW03_RS18465	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AW03_RS18475	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AW03_RS18480	COG0191	fructose-bisphosphate aldolase activity
AW03_RS18485	COG2204	response regulator
AW03_RS18490	COG4821	SIS domain
AW03_RS18495	COG0504	CTP synthase activity
AW03_RS18500	COG3343	RNA polymerase activity
AW03_RS18505	COG1960	acyl-CoA dehydrogenase activity
AW03_RS18510	COG2181	nitrate reductase activity
AW03_RS18510	COG0247	lactate metabolic process
AW03_RS18515	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AW03_RS18520	COG4294	response to UV
AW03_RS18530	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AW03_RS18535	COG1132	(ABC) transporter
AW03_RS18540	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AW03_RS18555	COG2181	nitrate reductase activity
AW03_RS18560	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AW03_RS18565	COG1140	nitrate reductase beta subunit
AW03_RS18570	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AW03_RS18575	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AW03_RS18585	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AW03_RS18590	COG2223	nitrite transmembrane transporter activity
AW03_RS18595	COG0018	arginyl-trna synthetase
AW03_RS18600	COG4506	Protein conserved in bacteria
AW03_RS18610	COG0535	radical SAM domain protein
AW03_RS18620	COG1131	(ABC) transporter
AW03_RS18625	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AW03_RS18630	COG0612	Peptidase, M16
AW03_RS18645	COG3391	amine dehydrogenase activity
AW03_RS18650	COG3391	amine dehydrogenase activity
AW03_RS18660	COG0457	Tetratricopeptide repeat
AW03_RS18690	COG1131	(ABC) transporter
AW03_RS18700	COG0010	Belongs to the arginase family
AW03_RS18705	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AW03_RS18710	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AW03_RS18720	COG1994	Peptidase M50
AW03_RS18725	COG1942	4-Oxalocrotonate Tautomerase
AW03_RS18730	COG1846	Transcriptional regulator
AW03_RS18735	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AW03_RS18745	COG0477	Major facilitator Superfamily
AW03_RS18750	COG1959	2 iron, 2 sulfur cluster binding
AW03_RS18755	COG3465	dGTPase activity
AW03_RS18760	COG1078	dGTPase activity
AW03_RS18765	COG4844	belongs to the
AW03_RS18775	COG0697	spore germination
AW03_RS18780	COG0095	Lipoate-protein ligase
AW03_RS18785	COG0583	DNA-binding transcription factor activity
AW03_RS18790	COG0280	phosphate acetyltransferase
AW03_RS18795	COG3253	May function as heme-dependent peroxidase
AW03_RS18800	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_RS18805	COG0436	Aminotransferase
AW03_RS18810	COG2814	Major facilitator Superfamily
AW03_RS18815	COG0151	Belongs to the GarS family
AW03_RS18820	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_RS18825	COG1917	Cupin 2, conserved barrel domain protein
AW03_RS18830	COG0077	Prephenate dehydratase
AW03_RS18835	COG2814	Major facilitator Superfamily
AW03_RS18840	COG0833	amino acid
AW03_RS18845	COG4187	Peptidase family M20/M25/M40
AW03_RS18850	COG1012	belongs to the aldehyde dehydrogenase family
AW03_RS18855	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AW03_RS18865	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AW03_RS18870	COG1091	dTDP-4-dehydrorhamnose reductase activity
AW03_RS18875	COG1088	dTDP-glucose 4,6-dehydratase activity
AW03_RS18880	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AW03_RS18885	COG3980	spore coat polysaccharide biosynthesis protein
AW03_RS18890	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
AW03_RS18895	COG2089	acid synthase
AW03_RS18900	COG0456	acetyltransferase
AW03_RS18905	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AW03_RS18910	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AW03_RS18915	COG0463	Glycosyl transferase, family 2
AW03_RS18930	COG2363	Small membrane protein
AW03_RS18935	COG2233	PERMEase
AW03_RS18945	COG1012	belongs to the aldehyde dehydrogenase family
AW03_RS18950	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AW03_RS18955	COG1216	Glycosyl transferase, family 2
AW03_RS18960	COG0351	phosphomethylpyrimidine kinase
AW03_RS18970	COG1621	beta-fructofuranosidase activity
AW03_RS18975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW03_RS18975	COG1263	PTS System
AW03_RS18985	COG3711	transcriptional antiterminator
AW03_RS18995	COG1404	Belongs to the peptidase S8 family
AW03_RS19000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AW03_RS19005	COG0778	Nitroreductase
AW03_RS19010	COG0772	Belongs to the SEDS family
AW03_RS19020	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AW03_RS19025	COG1845	cytochrome c oxidase, subunit III
AW03_RS19030	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AW03_RS19035	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AW03_RS19040	COG2261	transglycosylase associated protein
AW03_RS19045	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
AW03_RS19050	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AW03_RS19055	COG2246	polysaccharide biosynthetic process
AW03_RS19060	COG1309	transcriptional regulator
AW03_RS19070	COG3162	membrane
AW03_RS19075	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AW03_RS19080	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AW03_RS19085	COG2837	iron assimilation
AW03_RS19090	COG2822	iron ion transport
AW03_RS19095	COG0672	)-iron permease
AW03_RS19100	COG0352	thiamine-phosphate diphosphorylase activity
AW03_RS19105	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AW03_RS19110	COG0583	DNA-binding transcription factor activity
AW03_RS19115	COG1380	Effector of murein hydrolase LrgA
AW03_RS19120	COG1346	cytolysis
AW03_RS19125	COG2814	Major facilitator Superfamily
AW03_RS19130	COG4895	conserved protein (DUF2196)
AW03_RS19135	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AW03_RS19140	COG0346	lactoylglutathione lyase activity
AW03_RS19150	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AW03_RS19160	COG1404	Belongs to the peptidase S8 family
AW03_RS19165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW03_RS19165	COG1263	PTS System
AW03_RS19170	COG3711	transcriptional antiterminator
AW03_RS19175	COG1442	glycosyl transferase family 8
AW03_RS19180	COG5522	Integral membrane protein (intg_mem_TP0381)
AW03_RS19185	COG1846	Transcriptional regulator
AW03_RS19190	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AW03_RS19195	COG2234	aminopeptidase activity
AW03_RS19200	COG2357	RelA SpoT domain protein
AW03_RS19205	COG1575	Belongs to the MenA family. Type 1 subfamily
AW03_RS19220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW03_RS19225	COG1696	Membrane protein involved in D-alanine export
AW03_RS19230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AW03_RS19235	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AW03_RS19240	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
AW03_RS19245	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AW03_RS19250	COG1486	melibiose metabolic process
AW03_RS19255	COG1447	Phosphotransferase system cellobiose-specific component IIA
AW03_RS19260	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AW03_RS19265	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AW03_RS19270	COG3711	transcriptional antiterminator
AW03_RS19270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW03_RS19280	COG2094	Belongs to the DNA glycosylase MPG family
AW03_RS19285	COG0753	catalase activity
AW03_RS19290	COG2814	Major facilitator Superfamily
AW03_RS19295	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AW03_RS19300	COG1131	(ABC) transporter
AW03_RS19320	COG1595	DNA-templated transcription, initiation
AW03_RS19325	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AW03_RS19330	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AW03_RS19335	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AW03_RS19340	COG4988	ABC transporter
AW03_RS19345	COG1294	oxidase, subunit
AW03_RS19350	COG1271	oxidase subunit
AW03_RS19355	COG3493	citrate carrier protein
AW03_RS19360	COG0501	Belongs to the peptidase M48B family
AW03_RS19370	COG0726	polysaccharide deacetylase
AW03_RS19375	COG3842	ATPase activity
AW03_RS19380	COG2508	Transcriptional regulator
AW03_RS19385	COG1012	belongs to the aldehyde dehydrogenase family
AW03_RS19390	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW03_RS19400	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AW03_RS19405	COG1881	PFAM PEBP family protein
AW03_RS19410	COG0583	DNA-binding transcription factor activity
AW03_RS19420	COG4585	Histidine kinase
AW03_RS19425	COG2197	response regulator
AW03_RS19430	COG2195	Cleaves the N-terminal amino acid of tripeptides
AW03_RS19445	COG4894	glucomannan catabolic process
AW03_RS19450	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AW03_RS19455	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AW03_RS19460	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_RS19465	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AW03_RS19470	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AW03_RS19475	COG2610	gluconate transmembrane transporter activity
AW03_RS19485	COG0500	methyltransferase
AW03_RS19490	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AW03_RS19505	COG0693	protein deglycase activity
AW03_RS19505	COG0753	catalase activity
AW03_RS19510	COG2851	Citrate transporter
AW03_RS19515	COG2273	Hydrolase Family 16
AW03_RS19520	COG3711	transcriptional antiterminator
AW03_RS19530	COG2270	Major facilitator Superfamily
AW03_RS19535	COG0513	Belongs to the DEAD box helicase family
AW03_RS19540	COG3401	FG-GAP repeat protein
AW03_RS19540	COG2755	lipolytic protein G-D-S-L family
AW03_RS19560	COG0697	spore germination
AW03_RS19565	COG0589	response to stress
AW03_RS19570	COG2723	6-phospho-beta-galactosidase activity
AW03_RS19575	COG1263	PTS System
AW03_RS19575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW03_RS19575	COG2190	(PTS) system
AW03_RS19625	COG5444	nuclease activity
AW03_RS19650	COG0494	nUDIX hydrolase
AW03_RS19655	COG3507	Belongs to the glycosyl hydrolase 43 family
AW03_RS19665	COG2986	histidine ammonia-lyase
AW03_RS19670	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AW03_RS19675	COG1228	amidohydrolase
AW03_RS19680	COG0010	Belongs to the arginase family
AW03_RS19685	COG0833	amino acid
AW03_RS19690	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AW03_RS19695	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AW03_RS19700	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AW03_RS19705	COG2390	Transcriptional regulator
AW03_RS19715	COG3192	ethanolamine utilization protein
AW03_RS19720	COG2079	MmgE PrpD family protein
AW03_RS19725	COG1473	amidohydrolase
AW03_RS19730	COG1126	abc transporter atp-binding protein
AW03_RS19735	COG0765	amino acid transport
AW03_RS19740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW03_RS19745	COG0456	acetyltransferase
AW03_RS19750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AW03_RS19755	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
AW03_RS19760	COG0561	phosphatase activity
AW03_RS19790	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW03_RS19795	COG5294	Protein conserved in bacteria
AW03_RS19800	COG0577	efflux transmembrane transporter activity
AW03_RS19805	COG1136	(ABC) transporter
AW03_RS19810	COG2205	protein histidine kinase activity
AW03_RS19815	COG0745	RESPONSE REGULATOR receiver
AW03_RS19820	COG0191	fructose-bisphosphate aldolase activity
AW03_RS19825	COG1082	Xylose isomerase domain protein TIM barrel
AW03_RS19830	COG1082	Xylose isomerase domain protein TIM barrel
AW03_RS19835	COG0673	inositol 2-dehydrogenase activity
AW03_RS19840	COG2814	Major facilitator Superfamily
AW03_RS19845	COG1082	Xylose isomerase domain protein TIM barrel
AW03_RS19850	COG3962	Belongs to the TPP enzyme family
AW03_RS19855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AW03_RS19865	COG1012	belongs to the aldehyde dehydrogenase family
AW03_RS19870	COG1349	DNA-binding transcription factor activity
AW03_RS19875	COG0667	Aldo Keto reductase
AW03_RS19890	COG2814	Major facilitator Superfamily
AW03_RS19895	COG0326	Molecular chaperone. Has ATPase activity
AW03_RS19905	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_RS19910	COG1309	transcriptional regulator
AW03_RS19915	COG1012	belongs to the aldehyde dehydrogenase family
AW03_RS19920	COG1714	RDD family
AW03_RS19925	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AW03_RS19935	COG1714	RDD family
AW03_RS19940	COG2311	Membrane
AW03_RS19945	COG1917	Cupin 2, conserved barrel domain protein
AW03_RS19950	COG1309	transcriptional regulator
AW03_RS19955	COG1028	Short-chain dehydrogenase reductase Sdr
AW03_RS19960	COG1846	Transcriptional regulator
AW03_RS19965	COG1380	Effector of murein hydrolase LrgA
AW03_RS19970	COG1346	cytolysis
AW03_RS19975	COG5039	Polysaccharide pyruvyl transferase
AW03_RS19980	COG1929	Belongs to the glycerate kinase type-1 family
AW03_RS19985	COG1802	Transcriptional regulator
AW03_RS19990	COG1070	Carbohydrate kinase
AW03_RS19995	COG2610	gluconate transmembrane transporter activity
AW03_RS20000	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AW03_RS20005	COG0450	alkyl hydroperoxide reductase
AW03_RS20010	COG3634	alkyl hydroperoxide reductase activity
AW03_RS20020	COG2723	6-phospho-beta-galactosidase activity
AW03_RS20025	COG2190	(PTS) system
AW03_RS20030	COG2188	Transcriptional regulator
AW03_RS20045	COG1131	(ABC) transporter
AW03_RS20050	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
AW03_RS20060	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AW03_RS20075	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AW03_RS20090	COG1063	alcohol dehydrogenase
AW03_RS20110	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
AW03_RS20115	COG0456	acetyltransferase
AW03_RS20120	COG0457	Tetratricopeptide repeat
AW03_RS20130	COG0010	Belongs to the arginase family
AW03_RS20135	COG0833	amino acid
AW03_RS20140	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AW03_RS20145	COG3829	transcription factor binding
AW03_RS20150	COG5002	protein histidine kinase activity
AW03_RS20160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AW03_RS20165	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AW03_RS20170	COG4853	Protein conserved in bacteria
AW03_RS20175	COG4863	YycH protein
AW03_RS20180	COG5002	protein histidine kinase activity
AW03_RS20185	COG0745	RESPONSE REGULATOR receiver
AW03_RS20215	COG0346	lactoylglutathione lyase activity
AW03_RS20220	COG0305	Participates in initiation and elongation during chromosome replication
AW03_RS20245	COG2807	transmembrane transport
AW03_RS20250	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AW03_RS20255	COG0359	binds to the 23S rRNA
AW03_RS20260	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
AW03_RS20265	COG4241	membrane
AW03_RS20275	COG5577	PFAM Coat F domain
AW03_RS20280	COG1733	regulation of RNA biosynthetic process
AW03_RS20285	COG1227	inorganic diphosphatase activity
AW03_RS20300	COG2271	Major facilitator Superfamily
AW03_RS20305	COG0789	Transcriptional regulator
AW03_RS20305	COG4978	Transcriptional regulator
AW03_RS20315	COG4319	ketosteroid isomerase
AW03_RS20320	COG1357	PFAM Pentapeptide repeats (8 copies)
AW03_RS20325	COG2814	Major facilitator Superfamily
AW03_RS20330	COG0583	DNA-binding transcription factor activity
AW03_RS20335	COG2153	protein acetylation
AW03_RS20345	COG0583	DNA-binding transcription factor activity
AW03_RS20360	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW03_RS20365	COG1846	Transcriptional regulator
AW03_RS20370	COG2153	protein acetylation
AW03_RS20375	COG2364	Membrane
AW03_RS20380	COG0456	acetyltransferase
AW03_RS20385	COG2315	Protein conserved in bacteria
AW03_RS20390	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AW03_RS20395	COG1331	Highly conserved protein containing a thioredoxin domain
AW03_RS20400	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AW03_RS20405	COG0798	PFAM Bile acid sodium symporter
AW03_RS20410	COG0346	lactoylglutathione lyase activity
AW03_RS20415	COG0640	Transcriptional regulator
AW03_RS20425	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AW03_RS20430	COG1331	Highly conserved protein containing a thioredoxin domain
AW03_RS20435	COG0863	Belongs to the N(4) N(6)-methyltransferase family
AW03_RS20445	COG1331	Highly conserved protein containing a thioredoxin domain
AW03_RS20450	COG1266	CAAX protease self-immunity
AW03_RS20455	COG2814	Major facilitator Superfamily
AW03_RS20455	COG0477	Major facilitator Superfamily
AW03_RS20460	COG0110	maltose O-acetyltransferase activity
AW03_RS20465	COG0346	lactoylglutathione lyase activity
AW03_RS20470	COG1609	Transcriptional regulator
AW03_RS20475	COG0708	Exodeoxyribonuclease III
AW03_RS20480	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AW03_RS20485	COG0629	single-stranded DNA binding
AW03_RS20490	COG0360	Binds together with S18 to 16S ribosomal RNA
AW03_RS20495	COG0012	GTP binding
AW03_RS20500	COG0243	molybdopterin cofactor binding
AW03_RS20505	COG4481	Protein conserved in bacteria
AW03_RS20510	COG3949	Membrane
AW03_RS20520	COG1475	DNA binding
AW03_RS20525	COG1192	Involved in chromosome partitioning
AW03_RS20535	COG1475	DNA binding
AW03_RS20540	COG0357	Ribosomal RNA small subunit methyltransferase G
AW03_RS20545	COG0445	tRNA wobble uridine modification
AW03_RS20550	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AW03_RS20555	COG1847	R3H domain protein
AW03_RS20560	COG0706	membrane insertase activity
AW03_RS20565	COG0594	ribonuclease P activity
AW03_RS20650	COG1971	Probably functions as a manganese efflux pump
AW03_RS20655	COG2116	formate transmembrane transporter activity
AW03_RS20660	COG2116	formate transmembrane transporter activity