locus-tag	class	description
D0819_RS00090	COG4326	sporulation control protein
D0819_RS00100	COG5577	PFAM Coat F domain
D0819_RS00105	COG3340	Belongs to the peptidase S51 family
D0819_RS00110	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
D0819_RS00125	COG0753	catalase activity
D0819_RS00130	COG1116	anion transmembrane transporter activity
D0819_RS00135	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D0819_RS00140	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D0819_RS00145	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D0819_RS00155	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
D0819_RS00165	COG1476	TRANSCRIPTIONal
D0819_RS00175	COG3382	B3 4 domain protein
D0819_RS00180	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D0819_RS00190	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
D0819_RS00195	COG0789	Transcriptional regulator
D0819_RS00200	COG1664	Polymer-forming cytoskeletal
D0819_RS00205	COG1664	Polymer-forming cytoskeletal
D0819_RS00210	COG2766	serine protein kinase
D0819_RS00215	COG2718	Belongs to the UPF0229 family
D0819_RS00220	COG1846	Transcriptional regulator
D0819_RS00225	COG1566	PFAM secretion protein HlyD family protein
D0819_RS00230	COG2814	Major facilitator Superfamily
D0819_RS00235	COG0655	NAD(P)H dehydrogenase (quinone) activity
D0819_RS00255	COG1725	Transcriptional regulator
D0819_RS00260	COG1131	(ABC) transporter
D0819_RS00265	COG1131	(ABC) transporter
D0819_RS00270	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D0819_RS00275	COG1278	Cold shock
D0819_RS00280	COG1464	Belongs to the NlpA lipoprotein family
D0819_RS00285	COG3706	GGDEF domain
D0819_RS00290	COG1823	symporter activity
D0819_RS00320	COG5577	PFAM Coat F domain
D0819_RS00325	COG0737	Belongs to the 5'-nucleotidase family
D0819_RS00325	COG1525	nuclease
D0819_RS00325	COG4085	toxin activity
D0819_RS00330	COG3764	Sortase (surface protein transpeptidase)
D0819_RS00335	COG0564	pseudouridine synthase activity
D0819_RS00345	COG0517	IMP dehydrogenase activity
D0819_RS00350	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D0819_RS00355	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D0819_RS00355	COG3153	acetyltransferase
D0819_RS00365	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D0819_RS00370	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
D0819_RS00375	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
D0819_RS00380	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
D0819_RS00385	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
D0819_RS00390	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D0819_RS00395	COG2203	Gaf domain
D0819_RS00395	COG4585	Histidine kinase
D0819_RS00400	COG2197	response regulator
D0819_RS00405	COG0431	NADPH-dependent FMN reductase
D0819_RS00420	COG1388	LysM domain
D0819_RS00420	COG0791	NLP P60 protein
D0819_RS00425	COG1959	2 iron, 2 sulfur cluster binding
D0819_RS00430	COG0668	transmembrane transport
D0819_RS00435	COG2719	SpoVR family
D0819_RS00440	COG1785	Belongs to the alkaline phosphatase family
D0819_RS00445	COG1388	LysM domain
D0819_RS00445	COG0791	NLP P60 protein
D0819_RS00450	COG0583	DNA-binding transcription factor activity
D0819_RS00455	COG0372	Belongs to the citrate synthase family
D0819_RS00460	COG1028	Short-chain dehydrogenase reductase Sdr
D0819_RS00465	COG0531	amino acid
D0819_RS00470	COG0733	neurotransmitter:sodium symporter activity
D0819_RS00475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D0819_RS00480	COG0456	acetyltransferase
D0819_RS00495	COG1595	DNA-templated transcription, initiation
D0819_RS00500	COG0667	Aldo Keto reductase
D0819_RS00505	COG0204	Acyl-transferase
D0819_RS00510	COG1253	flavin adenine dinucleotide binding
D0819_RS00515	COG0789	Transcriptional regulator
D0819_RS00520	COG0436	Aminotransferase
D0819_RS00525	COG1253	flavin adenine dinucleotide binding
D0819_RS00530	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D0819_RS00535	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D0819_RS00540	COG0584	glycerophosphoryl diester phosphodiesterase
D0819_RS00550	COG0668	transmembrane transport
D0819_RS00555	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
D0819_RS00560	COG0726	polysaccharide deacetylase
D0819_RS00565	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D0819_RS00570	COG1757	Na H antiporter
D0819_RS00575	COG0589	response to stress
D0819_RS00585	COG1132	(ABC) transporter
D0819_RS00590	COG1132	(ABC) transporter
D0819_RS00595	COG0702	epimerase
D0819_RS00615	COG0189	ligase activity
D0819_RS00620	COG0189	ligase activity
D0819_RS00625	COG4399	Belongs to the UPF0754 family
D0819_RS00630	COG3679	Belongs to the UPF0342 family
D0819_RS00635	COG4335	DNA alkylation repair
D0819_RS00640	COG0561	phosphatase activity
D0819_RS00645	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D0819_RS00650	COG0475	glutathione-regulated potassium exporter activity
D0819_RS00655	COG0490	domain, Protein
D0819_RS00665	COG1024	Enoyl-CoA hydratase
D0819_RS00675	COG4152	abc transporter atp-binding protein
D0819_RS00680	COG1668	transmembrane transport
D0819_RS00690	COG0420	3'-5' exonuclease activity
D0819_RS00695	COG4717	serine-type aminopeptidase activity
D0819_RS00700	COG3481	metal-dependent phosphohydrolase, HD sub domain
D0819_RS00710	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D0819_RS00740	COG1846	Transcriptional regulator
D0819_RS00745	COG4980	gas vesicle protein
D0819_RS00760	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
D0819_RS00765	COG0537	adenosine 5'-monophosphoramidase activity
D0819_RS00770	COG1131	(ABC) transporter
D0819_RS00775	COG4473	ABC transporter
D0819_RS00785	COG1473	amidohydrolase
D0819_RS00790	COG3069	C4-dicarboxylate transmembrane transporter activity
D0819_RS00800	COG2329	Antibiotic biosynthesis monooxygenase
D0819_RS00805	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D0819_RS00810	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
D0819_RS00815	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
D0819_RS00820	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
D0819_RS00825	COG1309	transcriptional regulator
D0819_RS00830	COG1511	domain protein
D0819_RS00835	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D0819_RS00840	COG4377	Putative membrane peptidase family (DUF2324)
D0819_RS00850	COG1363	Peptidase, m42
D0819_RS00855	COG4405	Protein conserved in bacteria
D0819_RS00860	COG1301	dicarboxylic acid transport
D0819_RS00870	COG1234	tRNA 3'-trailer cleavage
D0819_RS00875	COG0095	Lipoate-protein ligase
D0819_RS00880	COG0702	epimerase
D0819_RS00885	COG0318	PFAM AMP-dependent synthetase and ligase
D0819_RS00895	COG0501	Belongs to the peptidase M48B family
D0819_RS00910	COG0604	alcohol dehydrogenase
D0819_RS00915	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
D0819_RS00920	COG0406	alpha-ribazole phosphatase activity
D0819_RS00925	COG0183	Belongs to the thiolase family
D0819_RS00930	COG0318	PFAM AMP-dependent synthetase and ligase
D0819_RS00935	COG1268	BioY protein
D0819_RS00940	COG0840	transmembrane signaling receptor activity
D0819_RS00945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D0819_RS00945	COG0723	plastoquinol--plastocyanin reductase activity
D0819_RS00950	COG1028	Short-chain dehydrogenase reductase Sdr
D0819_RS00960	COG4903	ComK protein
D0819_RS00965	COG1028	Short-chain dehydrogenase reductase Sdr
D0819_RS00975	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D0819_RS00990	COG0398	Pfam SNARE associated Golgi protein
D0819_RS00995	COG0681	Belongs to the peptidase S26 family
D0819_RS01000	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D0819_RS01005	COG1846	Transcriptional regulator
D0819_RS01010	COG0738	Major facilitator superfamily
D0819_RS01015	COG0673	inositol 2-dehydrogenase activity
D0819_RS01020	COG0561	phosphatase activity
D0819_RS01025	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D0819_RS01030	COG1609	Transcriptional regulator
D0819_RS01035	COG3180	Ammonia monooxygenase
D0819_RS01040	COG2814	Major facilitator Superfamily
D0819_RS01040	COG0477	Major facilitator Superfamily
D0819_RS01045	COG4533	DNA binding
D0819_RS01055	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
D0819_RS01060	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
D0819_RS01065	COG1074	ATP-dependent DNA helicase activity
D0819_RS01070	COG0420	3'-5' exonuclease activity
D0819_RS01075	COG0419	ATPase involved in DNA repair
D0819_RS01080	COG1403	HNH endonuclease
D0819_RS01120	COG5337	Spore coat protein CotH
D0819_RS01125	COG0179	Fumarylacetoacetate (FAA) hydrolase
D0819_RS01145	COG0367	asparagine synthase
D0819_RS01150	COG2318	DinB family
D0819_RS01155	COG1562	ergosterol biosynthetic process
D0819_RS01160	COG0534	Mate efflux family protein
D0819_RS01165	COG2207	Transcriptional regulator
D0819_RS01165	COG1917	Cupin 2, conserved barrel domain protein
D0819_RS01170	COG1609	Transcriptional regulator
D0819_RS01175	COG0673	inositol 2-dehydrogenase activity
D0819_RS01180	COG2318	DinB family
D0819_RS01185	COG1279	arginine transmembrane transporter activity
D0819_RS01190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D0819_RS01195	COG1357	PFAM Pentapeptide repeats (8 copies)
D0819_RS01200	COG2267	carboxylic ester hydrolase activity
D0819_RS01205	COG0529	Catalyzes the synthesis of activated sulfate
D0819_RS01210	COG2046	Belongs to the sulfate adenylyltransferase family
D0819_RS01215	COG0175	sulfate reduction
D0819_RS01220	COG2045	Belongs to the ComB family
D0819_RS01225	COG1809	phosphosulfolactate synthase activity
D0819_RS01230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D0819_RS01235	COG4948	Mandelate Racemase Muconate Lactonizing
D0819_RS01240	COG2814	Major facilitator Superfamily
D0819_RS01245	COG0454	-acetyltransferase
D0819_RS01250	COG2153	protein acetylation
D0819_RS01255	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
D0819_RS01255	COG0646	methionine synthase
D0819_RS01260	COG1666	GTP binding
D0819_RS01265	COG2996	Protein conserved in bacteria
D0819_RS01285	COG1695	Transcriptional regulator
D0819_RS01300	COG3227	Zinc metalloprotease (Elastase)
D0819_RS01305	COG1307	EDD domain protein, DegV family
D0819_RS01310	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D0819_RS01325	COG0561	phosphatase activity
D0819_RS01330	COG1073	alpha beta
D0819_RS01335	COG2151	metal-sulfur cluster biosynthetic enzyme
D0819_RS01345	COG0277	FAD linked oxidase domain protein
D0819_RS01350	COG2271	Major facilitator Superfamily
D0819_RS01355	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
D0819_RS01360	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
D0819_RS01370	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D0819_RS01375	COG0505	Belongs to the CarA family
D0819_RS01380	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D0819_RS01385	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
D0819_RS01400	COG2267	carboxylic ester hydrolase activity
D0819_RS01410	COG1744	ABC transporter substrate-binding protein PnrA-like
D0819_RS01425	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D0819_RS01430	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D0819_RS01435	COG5504	Zn-dependent protease
D0819_RS01440	COG0444	Belongs to the ABC transporter superfamily
D0819_RS01445	COG4608	Belongs to the ABC transporter superfamily
D0819_RS01455	COG0601	transmembrane transport
D0819_RS01460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D0819_RS01470	COG0180	Tryptophanyl-tRNA synthetase
D0819_RS01475	COG4166	transmembrane transport
D0819_RS01480	COG0601	transmembrane transport
D0819_RS01485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D0819_RS01490	COG0444	Belongs to the ABC transporter superfamily
D0819_RS01495	COG4608	Belongs to the ABC transporter superfamily
D0819_RS01500	COG2814	Major facilitator Superfamily
D0819_RS01505	COG0456	acetyltransferase
D0819_RS01510	COG1393	Belongs to the ArsC family
D0819_RS01515	COG0861	Integral membrane protein TerC family
D0819_RS01525	COG4862	establishment of competence for transformation
D0819_RS01535	COG4469	Competence protein
D0819_RS01540	COG1164	Oligoendopeptidase f
D0819_RS01550	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
D0819_RS01555	COG2346	COG2346, Truncated hemoglobins
D0819_RS01560	COG0741	lytic transglycosylase activity
D0819_RS01565	COG4116	CYTH
D0819_RS01575	COG2357	RelA SpoT domain protein
D0819_RS01580	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D0819_RS01585	COG0564	pseudouridine synthase activity
D0819_RS01590	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
D0819_RS01595	COG0569	domain protein
D0819_RS01595	COG0475	glutathione-regulated potassium exporter activity
D0819_RS01600	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
D0819_RS01605	COG0352	thiamine-phosphate diphosphorylase activity
D0819_RS01610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D0819_RS01615	COG2104	thiamine diphosphate biosynthetic process
D0819_RS01620	COG2022	thiamine diphosphate biosynthetic process
D0819_RS01625	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D0819_RS01630	COG0351	phosphomethylpyrimidine kinase
D0819_RS01635	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
D0819_RS01690	COG0210	DNA helicase
D0819_RS01700	COG2153	protein acetylation
D0819_RS01705	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
D0819_RS01710	COG2382	esterase
D0819_RS01715	COG0626	cystathionine gamma-synthase activity
D0819_RS01720	COG0626	cystathionine gamma-synthase activity
D0819_RS01725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D0819_RS01785	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
D0819_RS01790	COG1028	Short-chain dehydrogenase reductase Sdr
D0819_RS01800	COG3711	transcriptional antiterminator
D0819_RS01800	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0819_RS01805	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0819_RS01805	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0819_RS01805	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0819_RS01810	COG1482	cell wall glycoprotein biosynthetic process
D0819_RS01820	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D0819_RS01830	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D0819_RS01845	COG0109	protoheme IX farnesyltransferase activity
D0819_RS01855	COG0726	polysaccharide deacetylase
D0819_RS01875	COG2205	protein histidine kinase activity
D0819_RS01885	COG3383	formate dehydrogenase (NAD+) activity
D0819_RS01890	COG2427	Protein of unknown function (DUF1641)
D0819_RS01900	COG1051	belongs to the nudix hydrolase family
D0819_RS01910	COG2124	cytochrome p450
D0819_RS01915	COG1819	glycosyl
D0819_RS01925	COG1587	Uroporphyrinogen-III synthase
D0819_RS01930	COG0390	transport system, permease component
D0819_RS01935	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D0819_RS01940	COG0697	spore germination
D0819_RS01945	COG4297	protein containing double-stranded beta helix domain
D0819_RS01955	COG1252	NADH dehydrogenase
D0819_RS01960	COG1904	glucuronate isomerase
D0819_RS01965	COG2211	Major facilitator Superfamily
D0819_RS01970	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
D0819_RS01975	COG1063	alcohol dehydrogenase
D0819_RS01980	COG1312	Catalyzes the dehydration of D-mannonate
D0819_RS01985	COG1028	Short-chain dehydrogenase reductase Sdr
D0819_RS01990	COG2271	Major facilitator Superfamily
D0819_RS01995	COG1609	Transcriptional regulator
D0819_RS02000	COG0246	Mannitol dehydrogenase
D0819_RS02005	COG2721	sulfolactate sulfo-lyase activity
D0819_RS02010	COG0730	response to heat
D0819_RS02015	COG2318	DinB family
D0819_RS02020	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D0819_RS02025	COG0457	Tetratricopeptide repeat
D0819_RS02035	COG2350	Protein conserved in bacteria
D0819_RS02040	COG1388	LysM domain
D0819_RS02040	COG3409	Peptidoglycan-binding domain 1 protein
D0819_RS02040	COG5632	N-Acetylmuramoyl-L-alanine amidase
D0819_RS02050	COG4195	phage-related replication protein
D0819_RS02055	COG3546	catalase activity
D0819_RS02060	COG2856	Zn peptidase
D0819_RS02065	COG1396	sequence-specific DNA binding
D0819_RS02075	COG1522	sequence-specific DNA binding
D0819_RS02080	COG1484	DNA-dependent DNA replication
D0819_RS02100	COG1595	DNA-templated transcription, initiation
D0819_RS02105	COG3728	DNA packaging
D0819_RS02105	COG5484	DNA packaging
D0819_RS02110	COG1783	phage Terminase large subunit
D0819_RS02115	COG5518	Phage portal protein
D0819_RS02120	COG0338	D12 class N6 adenine-specific DNA methyltransferase
D0819_RS02125	COG4653	Phage capsid family
D0819_RS02175	COG3953	SLT domain
D0819_RS02175	COG5412	phage tail tape measure protein
D0819_RS02180	COG1652	LysM domain
D0819_RS02185	COG4193	domain, Protein
D0819_RS02195	COG3628	GPW Gp25 family protein
D0819_RS02200	COG3299	homolog of phage Mu protein gp47
D0819_RS02205	COG3778	Protein conserved in bacteria
D0819_RS02245	COG5632	N-Acetylmuramoyl-L-alanine amidase
D0819_RS02245	COG3409	Peptidoglycan-binding domain 1 protein
D0819_RS02265	COG0306	phosphate transporter
D0819_RS02270	COG1392	Phosphate transport regulator
D0819_RS02275	COG0531	amino acid
D0819_RS02280	COG0346	lactoylglutathione lyase activity
D0819_RS02285	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
D0819_RS02290	COG0463	Glycosyl transferase, family 2
D0819_RS02295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D0819_RS02300	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D0819_RS02305	COG2362	D-Aminopeptidase
D0819_RS02310	COG0601	transmembrane transport
D0819_RS02315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D0819_RS02320	COG0444	Belongs to the ABC transporter superfamily
D0819_RS02325	COG4166	transmembrane transport
D0819_RS02330	COG1619	proteins homologs of microcin C7 resistance protein MccF
D0819_RS02335	COG4948	Mandelate Racemase Muconate Lactonizing
D0819_RS02340	COG0791	NLP P60 protein
D0819_RS02345	COG4608	Belongs to the ABC transporter superfamily
D0819_RS02350	COG2706	6-phosphogluconolactonase activity
D0819_RS02355	COG1834	amidinotransferase
D0819_RS02360	COG1607	acyl-coa hydrolase
D0819_RS02365	COG1017	nitric oxide dioxygenase activity
D0819_RS02365	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D0819_RS02375	COG2323	membrane
D0819_RS02380	COG2318	DinB family
D0819_RS02385	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D0819_RS02390	COG2076	Multidrug Resistance protein
D0819_RS02395	COG2076	Multidrug Resistance protein
D0819_RS02400	COG0788	formyltetrahydrofolate deformylase activity
D0819_RS02405	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D0819_RS02410	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
D0819_RS02415	COG1764	response to oxidative stress
D0819_RS02420	COG1846	Transcriptional regulator
D0819_RS02425	COG1764	response to oxidative stress
D0819_RS02430	COG0590	tRNA wobble adenosine to inosine editing
D0819_RS02435	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D0819_RS02440	COG1404	Belongs to the peptidase S8 family
D0819_RS02445	COG1366	Belongs to the anti-sigma-factor antagonist family
D0819_RS02450	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D0819_RS02455	COG1122	ATPase activity
D0819_RS02460	COG4721	ABC-type cobalt transport system, permease component
D0819_RS02470	COG0745	RESPONSE REGULATOR receiver
D0819_RS02475	COG5002	protein histidine kinase activity
D0819_RS02475	COG3850	Histidine kinase
D0819_RS02480	COG3212	peptidase
D0819_RS02485	COG3212	peptidase
D0819_RS02500	COG2239	Acts as a magnesium transporter
D0819_RS02505	COG0789	Transcriptional regulator
D0819_RS02520	COG1846	Transcriptional regulator
D0819_RS02525	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D0819_RS02530	COG0726	polysaccharide deacetylase
D0819_RS02535	COG1408	metallophosphoesterase
D0819_RS02545	COG0463	Glycosyl transferase, family 2
D0819_RS02550	COG3285	dna ligase
D0819_RS02550	COG1793	dna ligase
D0819_RS02555	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
D0819_RS02560	COG5001	Diguanylate cyclase
D0819_RS02560	COG3300	MHYT domain
D0819_RS02565	COG0586	Pfam SNARE associated Golgi protein
D0819_RS02570	COG0861	Integral membrane protein TerC family
D0819_RS02575	COG1191	sigma factor activity
D0819_RS02595	COG0501	Belongs to the peptidase M48B family
D0819_RS02600	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D0819_RS02615	COG3594	Acyltransferase
D0819_RS02620	COG5002	protein histidine kinase activity
D0819_RS02625	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D0819_RS02635	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
D0819_RS02640	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
D0819_RS02645	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D0819_RS02650	COG0436	Aminotransferase
D0819_RS02655	COG1850	ribulose-bisphosphate carboxylase activity
D0819_RS02660	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
D0819_RS02665	COG0235	Class ii aldolase
D0819_RS02670	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
D0819_RS02675	COG3339	Conserved Protein
D0819_RS02690	COG3852	Histidine kinase
D0819_RS02695	COG1846	Transcriptional regulator
D0819_RS02700	COG1360	Flagellar Motor Protein
D0819_RS02705	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D0819_RS02710	COG0542	response to heat
D0819_RS02715	COG3949	Membrane
D0819_RS02720	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
D0819_RS02725	COG0720	synthase
D0819_RS02730	COG0602	queuosine metabolic process
D0819_RS02735	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
D0819_RS02740	COG1733	regulation of RNA biosynthetic process
D0819_RS02745	COG1028	Short-chain dehydrogenase reductase Sdr
D0819_RS02750	COG1388	LysM domain
D0819_RS02750	COG4641	Protein conserved in bacteria
D0819_RS02755	COG1388	LysM domain
D0819_RS02760	COG3858	chitin binding
D0819_RS02770	COG4873	Protein conserved in bacteria
D0819_RS02780	COG3773	Cell wall hydrolase
D0819_RS02785	COG2244	polysaccharide biosynthetic process
D0819_RS02790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D0819_RS02795	COG2217	Heavy metal translocating P-type atpase
D0819_RS02805	COG0006	proline dipeptidase activity
D0819_RS02810	COG1609	Transcriptional regulator
D0819_RS02815	COG3711	transcriptional antiterminator
D0819_RS02820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0819_RS02820	COG2190	(PTS) system
D0819_RS02820	COG1263	PTS System
D0819_RS02825	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0819_RS02830	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D0819_RS02840	COG1533	DNA photolyase activity
D0819_RS02845	COG0456	acetyltransferase
D0819_RS02850	COG0840	transmembrane signaling receptor activity
D0819_RS02855	COG2084	Dehydrogenase
D0819_RS02860	COG4257	antibiotic catabolic process
D0819_RS02865	COG2340	Cysteine-rich secretory protein family
D0819_RS02870	COG0768	penicillin binding
D0819_RS02875	COG4191	Histidine kinase
D0819_RS02880	COG0436	Aminotransferase
D0819_RS02890	COG0835	chemotaxis
D0819_RS02890	COG0784	Response regulator, receiver
D0819_RS02900	COG2814	Major facilitator Superfamily
D0819_RS02905	COG1376	ErfK ybiS ycfS ynhG family protein
D0819_RS02910	COG1408	metallophosphoesterase
D0819_RS02915	COG1028	Short-chain dehydrogenase reductase Sdr
D0819_RS02920	COG2200	EAL domain
D0819_RS02925	COG4703	Protein of unknown function (DUF1797)
D0819_RS02930	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
D0819_RS02940	COG0517	IMP dehydrogenase activity
D0819_RS02945	COG0583	DNA-binding transcription factor activity
D0819_RS02950	COG0716	FMN binding
D0819_RS02960	COG0716	FMN binding
D0819_RS02965	COG2171	N-acyltransferase activity
D0819_RS02970	COG1473	amidohydrolase
D0819_RS02980	COG0668	transmembrane transport
D0819_RS02985	COG0450	alkyl hydroperoxide reductase
D0819_RS02990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D0819_RS03005	COG0746	molybdenum cofactor guanylyltransferase activity
D0819_RS03010	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D0819_RS03015	COG0303	'Molybdopterin
D0819_RS03020	COG1763	Mo-molybdopterin cofactor biosynthetic process
D0819_RS03025	COG0314	molybdopterin synthase activity
D0819_RS03030	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
D0819_RS03035	COG1132	(ABC) transporter
D0819_RS03040	COG1132	(ABC) transporter
D0819_RS03050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D0819_RS03055	COG1136	(ABC) transporter
D0819_RS03060	COG0577	efflux transmembrane transporter activity
D0819_RS03065	COG1349	DNA-binding transcription factor activity
D0819_RS03070	COG1105	Belongs to the carbohydrate kinase PfkB family
D0819_RS03075	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0819_RS03075	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0819_RS03075	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0819_RS03080	COG0681	Belongs to the peptidase S26 family
D0819_RS03090	COG0488	(ABC) transporter
D0819_RS03095	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D0819_RS03100	COG2309	aminopeptidase activity
D0819_RS03110	COG1077	Cell shape determining protein MreB Mrl
D0819_RS03115	COG2002	toxin-antitoxin pair type II binding
D0819_RS03120	COG3852	Histidine kinase
D0819_RS03125	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
D0819_RS03125	COG2105	PFAM AIG2 family protein
D0819_RS03130	COG0569	domain protein
D0819_RS03135	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
D0819_RS03140	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D0819_RS03145	COG5503	Protein of unknown function (DUF1447)
D0819_RS03150	COG0561	phosphatase activity
D0819_RS03155	COG0242	peptide deformylase activity
D0819_RS03165	COG0497	DNA recombination
D0819_RS03170	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D0819_RS03175	COG0022	dehydrogenase e1 component
D0819_RS03180	COG0508	dehydrogenase complex catalyzes the overall conversion of
D0819_RS03185	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D0819_RS03190	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D0819_RS03200	COG1982	Orn Lys Arg decarboxylase major
D0819_RS03205	COG4476	Belongs to the UPF0223 family
D0819_RS03210	COG4493	Belongs to the UPF0637 family
D0819_RS03220	COG0483	inositol monophosphate 1-phosphatase activity
D0819_RS03230	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
D0819_RS03250	COG1595	DNA-templated transcription, initiation
D0819_RS03270	COG1217	gtp-binding protein TYPA
D0819_RS03280	COG4896	Protein conserved in bacteria
D0819_RS03290	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
D0819_RS03295	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D0819_RS03300	COG2066	Belongs to the glutaminase family
D0819_RS03305	COG4838	Belongs to the UPF0358 family
D0819_RS03310	COG0772	Belongs to the SEDS family
D0819_RS03315	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
D0819_RS03320	COG1612	heme a metabolic process
D0819_RS03325	COG0109	protoheme IX farnesyltransferase activity
D0819_RS03330	COG2010	Cytochrome c
D0819_RS03330	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D0819_RS03335	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D0819_RS03340	COG1845	cytochrome c oxidase, subunit III
D0819_RS03345	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
D0819_RS03350	COG3336	cytochrome c oxidase
D0819_RS03360	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
D0819_RS03365	COG2340	Cysteine-rich secretory protein family
D0819_RS03380	COG3679	Belongs to the UPF0342 family
D0819_RS03385	COG4471	UPF0298 protein
D0819_RS03390	COG0742	ribosomal rna small subunit methyltransferase
D0819_RS03395	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
D0819_RS03400	COG3314	Sporulation integral membrane protein YlbJ
D0819_RS03405	COG1752	Esterase of the alpha-beta hydrolase superfamily
D0819_RS03410	COG3480	Lon protease (S16) C-terminal proteolytic domain
D0819_RS03415	COG1323	Belongs to the UPF0348 family
D0819_RS03425	COG1399	metal-binding, possibly nucleic acid-binding protein
D0819_RS03440	COG0454	-acetyltransferase
D0819_RS03445	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D0819_RS03450	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
D0819_RS03455	COG2001	Belongs to the MraZ family
D0819_RS03460	COG0275	rRNA processing
D0819_RS03465	COG4839	cell division protein FtsL
D0819_RS03470	COG0768	penicillin binding
D0819_RS03475	COG0768	penicillin binding
D0819_RS03480	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
D0819_RS03485	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D0819_RS03490	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
D0819_RS03495	COG0772	Belongs to the SEDS family
D0819_RS03500	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D0819_RS03505	COG0812	UDP-N-acetylmuramate dehydrogenase activity
D0819_RS03510	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
D0819_RS03515	COG3879	Bacterial protein of unknown function (DUF881)
D0819_RS03520	COG3879	Bacterial protein of unknown function (DUF881)
D0819_RS03525	COG3856	small basic protein
D0819_RS03530	COG0849	cell division
D0819_RS03535	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
D0819_RS03540	COG1404	Belongs to the peptidase S8 family
D0819_RS03540	COG4412	M6 family metalloprotease domain protein
D0819_RS03550	COG1191	sigma factor activity
D0819_RS03555	COG1191	sigma factor activity
D0819_RS03560	COG1119	ATPase activity
D0819_RS03565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D0819_RS03570	COG1873	PFAM PRC-barrel domain
D0819_RS03575	COG1496	oxidoreductase activity
D0819_RS03580	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
D0819_RS03585	COG1799	cell septum assembly
D0819_RS03590	COG0762	integral membrane protein
D0819_RS03595	COG2302	S4 RNA-binding domain
D0819_RS03600	COG3599	regulation of cell shape
D0819_RS03605	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
D0819_RS03610	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D0819_RS03615	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
D0819_RS03620	COG0564	pseudouridine synthase activity
D0819_RS03625	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
D0819_RS03630	COG2233	PERMEase
D0819_RS03635	COG0540	Belongs to the ATCase OTCase family
D0819_RS03640	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D0819_RS03645	COG0505	Belongs to the CarA family
D0819_RS03650	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D0819_RS03655	COG0543	2 iron, 2 sulfur cluster binding
D0819_RS03660	COG0167	dihydroorotate dehydrogenase activity
D0819_RS03665	COG0284	orotidine-5'-phosphate decarboxylase activity
D0819_RS03670	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
D0819_RS03675	COG0175	sulfate reduction
D0819_RS03680	COG0306	phosphate transporter
D0819_RS03685	COG2046	Belongs to the sulfate adenylyltransferase family
D0819_RS03690	COG0529	Catalyzes the synthesis of activated sulfate
D0819_RS03695	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D0819_RS03700	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
D0819_RS03705	COG1648	precorrin-2 dehydrogenase activity
D0819_RS03710	COG1293	RNA-binding protein homologous to eukaryotic snRNP
D0819_RS03715	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D0819_RS03720	COG1561	YicC-like family, N-terminal region
D0819_RS03730	COG0194	GDP metabolic process
D0819_RS03735	COG1758	RNA polymerase activity
D0819_RS03740	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D0819_RS03745	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D0819_RS03750	COG0242	peptide deformylase activity
D0819_RS03755	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
D0819_RS03760	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D0819_RS03760	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D0819_RS03765	COG0820	rRNA (adenine-C2-)-methyltransferase activity
D0819_RS03770	COG0631	protein serine/threonine phosphatase activity
D0819_RS03775	COG2815	serine threonine protein kinase
D0819_RS03775	COG0515	serine threonine protein kinase
D0819_RS03780	COG1162	GTPase activity
D0819_RS03785	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D0819_RS03790	COG1564	THIamine pyrophosphokinase
D0819_RS03800	COG0227	Belongs to the bacterial ribosomal protein bL28 family
D0819_RS03805	COG1302	Protein conserved in bacteria
D0819_RS03810	COG1461	Dihydroxyacetone kinase
D0819_RS03815	COG1760	l-serine dehydratase
D0819_RS03820	COG1760	l-serine dehydratase
D0819_RS03825	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D0819_RS03830	COG2050	protein possibly involved in aromatic compounds catabolism
D0819_RS03830	COG1349	DNA-binding transcription factor activity
D0819_RS03835	COG0416	fatty acid biosynthetic process
D0819_RS03840	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D0819_RS03845	COG1028	Short-chain dehydrogenase reductase Sdr
D0819_RS03855	COG0571	ribonuclease III activity
D0819_RS03860	COG1196	nuclear chromosome segregation
D0819_RS03865	COG0552	protein localization to endoplasmic reticulum
D0819_RS03875	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
D0819_RS03880	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D0819_RS03885	COG0228	four-way junction DNA binding
D0819_RS03890	COG1837	Belongs to the UPF0109 family
D0819_RS03900	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
D0819_RS03905	COG0336	Belongs to the RNA methyltransferase TrmD family
D0819_RS03910	COG0335	large ribosomal subunit rRNA binding
D0819_RS03915	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D0819_RS03920	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
D0819_RS03930	COG2257	FlhB HrpN YscU SpaS Family
D0819_RS03935	COG0045	succinate-CoA ligase (ADP-forming) activity
D0819_RS03940	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
D0819_RS03945	COG0758	DNA mediated transformation
D0819_RS03950	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D0819_RS03955	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
D0819_RS03960	COG4974	Belongs to the 'phage' integrase family
D0819_RS03965	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
D0819_RS03970	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
D0819_RS03975	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
D0819_RS03980	COG1815	bacterial-type flagellum-dependent cell motility
D0819_RS03985	COG1558	bacterial-type flagellum-dependent cell motility
D0819_RS03990	COG1677	Flagellar hook-basal body complex protein FliE
D0819_RS03995	COG1766	The M ring may be actively involved in energy transduction
D0819_RS04000	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D0819_RS04005	COG1317	bacterial-type flagellum organization
D0819_RS04010	COG1157	protein secretion by the type III secretion system
D0819_RS04015	COG2882	bacterial-type flagellum organization
D0819_RS04020	COG3334	PFAM MgtE intracellular
D0819_RS04025	COG3144	bacterial-type flagellum assembly
D0819_RS04030	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
D0819_RS04035	COG4786	Flagellar basal body rod
D0819_RS04040	COG1582	Flagellar protein (FlbD)
D0819_RS04045	COG1580	Controls the rotational direction of flagella during chemotaxis
D0819_RS04050	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D0819_RS04055	COG1776	CheC inhibitor of MCP methylation
D0819_RS04055	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D0819_RS04060	COG2201	protein-glutamate methylesterase activity
D0819_RS04065	COG3190	flagellar
D0819_RS04070	COG1338	Plays a role in the flagellum-specific transport system
D0819_RS04075	COG1987	bacterial-type flagellum assembly
D0819_RS04080	COG1684	flagellar biosynthetic protein fliR
D0819_RS04085	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D0819_RS04090	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D0819_RS04095	COG1419	protein localization to endoplasmic reticulum
D0819_RS04100	COG0455	bacterial-type flagellum organization
D0819_RS04105	COG2201	protein-glutamate methylesterase activity
D0819_RS04110	COG0643	Histidine kinase
D0819_RS04110	COG2198	Histidine kinase
D0819_RS04115	COG0835	chemotaxis
D0819_RS04120	COG1776	CheC inhibitor of MCP methylation
D0819_RS04125	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
D0819_RS04130	COG1191	sigma factor activity
D0819_RS04140	COG0052	Belongs to the universal ribosomal protein uS2 family
D0819_RS04145	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
D0819_RS04150	COG0528	UMP kinase activity
D0819_RS04155	COG0233	cytoplasmic translational termination
D0819_RS04160	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
D0819_RS04165	COG4589	Belongs to the CDS family
D0819_RS04170	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
D0819_RS04175	COG0750	zinc metalloprotease
D0819_RS04180	COG0442	prolyl-tRNA aminoacylation
D0819_RS04185	COG2176	DNA-directed DNA polymerase activity
D0819_RS04190	COG0779	Required for maturation of 30S ribosomal subunits
D0819_RS04195	COG0195	Participates in both transcription termination and antitermination
D0819_RS04200	COG2740	Nucleic-acid-binding protein implicated in transcription termination
D0819_RS04205	COG1358	cellular component organization or biogenesis
D0819_RS04210	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
D0819_RS04215	COG1550	Protein conserved in bacteria
D0819_RS04220	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
D0819_RS04225	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
D0819_RS04230	COG0196	riboflavin kinase activity
D0819_RS04235	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
D0819_RS04240	COG1185	polyribonucleotide nucleotidyltransferase activity
D0819_RS04245	COG0726	polysaccharide deacetylase
D0819_RS04250	COG0612	Peptidase, M16
D0819_RS04255	COG1873	PFAM PRC-barrel domain
D0819_RS04260	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D0819_RS04265	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D0819_RS04270	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D0819_RS04275	COG0527	aspartate kinase activity
D0819_RS04280	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D0819_RS04285	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D0819_RS04290	COG0740	serine-type endopeptidase activity
D0819_RS04300	COG1674	ftsk spoiiie
D0819_RS04300	COG4980	gas vesicle protein
D0819_RS04305	COG2188	Transcriptional regulator
D0819_RS04310	COG2814	Major facilitator Superfamily
D0819_RS04315	COG0612	Peptidase, M16
D0819_RS04320	COG0612	Peptidase, M16
D0819_RS04325	COG0300	oxidoreductase activity
D0819_RS04340	COG1426	Protein conserved in bacteria
D0819_RS04345	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D0819_RS04350	COG1546	Belongs to the CinA family
D0819_RS04350	COG1058	Belongs to the CinA family
D0819_RS04355	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
D0819_RS04360	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D0819_RS04365	COG1418	mRNA catabolic process
D0819_RS04370	COG1692	metallophosphoesterase
D0819_RS04375	COG2359	stage V sporulation protein S
D0819_RS04380	COG1063	alcohol dehydrogenase
D0819_RS04385	COG0156	8-amino-7-oxononanoate synthase activity
D0819_RS04390	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D0819_RS04395	COG4550	Control of competence regulator ComK, YlbF/YmcA
D0819_RS04405	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
D0819_RS04410	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
D0819_RS04425	COG3226	Transcriptional regulator
D0819_RS04430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D0819_RS04440	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D0819_RS04445	COG3321	synthase
D0819_RS04450	COG2070	2-Nitropropane dioxygenase
D0819_RS04450	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D0819_RS04455	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D0819_RS04460	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D0819_RS04465	COG3425	synthase
D0819_RS04470	COG1024	Enoyl-CoA hydratase
D0819_RS04475	COG1024	Enoyl-CoA hydratase
D0819_RS04480	COG0300	oxidoreductase activity
D0819_RS04480	COG0318	PFAM AMP-dependent synthetase and ligase
D0819_RS04480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0819_RS04480	COG1028	Short-chain dehydrogenase reductase Sdr
D0819_RS04480	COG3321	synthase
D0819_RS04485	COG0300	oxidoreductase activity
D0819_RS04485	COG4221	oxidoreductase activity
D0819_RS04485	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D0819_RS04485	COG3321	synthase
D0819_RS04490	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0819_RS04490	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D0819_RS04490	COG3321	synthase
D0819_RS04490	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D0819_RS04490	COG1028	Short-chain dehydrogenase reductase Sdr
D0819_RS04495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0819_RS04495	COG3321	synthase
D0819_RS04495	COG4221	oxidoreductase activity
D0819_RS04495	COG1028	Short-chain dehydrogenase reductase Sdr
D0819_RS04500	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
D0819_RS04500	COG3321	synthase
D0819_RS04500	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D0819_RS04500	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D0819_RS04505	COG2124	cytochrome p450
D0819_RS04515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D0819_RS04520	COG1404	Belongs to the peptidase S8 family
D0819_RS04530	COG4195	phage-related replication protein
D0819_RS04535	COG1764	response to oxidative stress
D0819_RS04540	COG2076	Multidrug Resistance protein
D0819_RS04545	COG2076	Multidrug Resistance protein
D0819_RS04560	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
D0819_RS04565	COG1923	regulation of RNA biosynthetic process
D0819_RS04580	COG1780	Probably involved in ribonucleotide reductase function
D0819_RS04585	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D0819_RS04590	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D0819_RS04595	COG4112	unkown
D0819_RS04600	COG0860	N-Acetylmuramoyl-L-alanine amidase
D0819_RS04605	COG0464	growth
D0819_RS04610	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D0819_RS04615	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
D0819_RS04620	COG0789	Transcriptional regulator
D0819_RS04625	COG0174	glutamine synthetase
D0819_RS04650	COG4282	regulation of fungal-type cell wall biogenesis
D0819_RS04660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D0819_RS04675	COG0135	phosphoribosylanthranilate isomerase activity
D0819_RS04680	COG2211	Major facilitator Superfamily
D0819_RS04685	COG3507	Belongs to the glycosyl hydrolase 43 family
D0819_RS04690	COG1940	carbohydrate kinase activity
D0819_RS04695	COG2115	Belongs to the xylose isomerase family
D0819_RS04700	COG1070	Carbohydrate kinase
D0819_RS04710	COG1525	nuclease
D0819_RS04715	COG2814	Major facilitator Superfamily
D0819_RS04720	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D0819_RS04730	COG0756	dUTP diphosphatase activity
D0819_RS04770	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D0819_RS04785	COG3832	glyoxalase III activity
D0819_RS04795	COG0697	spore germination
D0819_RS04800	COG0531	amino acid
D0819_RS04830	COG4195	phage-related replication protein
D0819_RS04840	COG0346	lactoylglutathione lyase activity
D0819_RS04845	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
D0819_RS04850	COG1388	LysM domain
D0819_RS04855	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D0819_RS04860	COG4224	UPF0291 protein
D0819_RS04865	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D0819_RS04875	COG3763	UPF0154 protein
D0819_RS04885	COG0785	Cytochrome C biogenesis protein
D0819_RS04890	COG2201	protein-glutamate methylesterase activity
D0819_RS04895	COG4846	Membrane protein involved in cytochrome C biogenesis
D0819_RS04905	COG0071	Belongs to the small heat shock protein (HSP20) family
D0819_RS04920	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
D0819_RS04925	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D0819_RS04945	COG0824	Thioesterase
D0819_RS04955	COG4841	protein insertion into membrane
D0819_RS04960	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
D0819_RS04965	COG1832	CoA-binding protein
D0819_RS04970	COG0187	DNA topoisomerase II activity
D0819_RS04975	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D0819_RS04985	COG1115	amino acid carrier protein
D0819_RS04990	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
D0819_RS05000	COG5520	Belongs to the glycosyl hydrolase 30 family
D0819_RS05005	COG3507	Belongs to the glycosyl hydrolase 43 family
D0819_RS05010	COG2246	polysaccharide biosynthetic process
D0819_RS05015	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D0819_RS05020	COG0586	Pfam SNARE associated Golgi protein
D0819_RS05025	COG2404	hydrolase activity, acting on ester bonds
D0819_RS05030	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D0819_RS05035	COG1024	Enoyl-CoA hydratase
D0819_RS05040	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D0819_RS05045	COG0511	ligase activity, forming carbon-carbon bonds
D0819_RS05050	COG0439	Biotin carboxylase
D0819_RS05055	COG0318	PFAM AMP-dependent synthetase and ligase
D0819_RS05060	COG1960	acyl-CoA dehydrogenase activity
D0819_RS05075	COG1649	PFAM Uncharacterised BCR, COG1649
D0819_RS05085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0819_RS05085	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
D0819_RS05090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0819_RS05095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0819_RS05100	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0819_RS05105	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0819_RS05110	COG2027	D-alanyl-D-alanine carboxypeptidase
D0819_RS05115	COG2017	converts alpha-aldose to the beta-anomer
D0819_RS05120	COG0534	Mate efflux family protein
D0819_RS05135	COG0582	viral genome integration into host DNA
D0819_RS05140	COG0166	Belongs to the GPI family
D0819_RS05145	COG0405	Gamma-glutamyltransferase
D0819_RS05150	COG0583	DNA-binding transcription factor activity
D0819_RS05155	COG0604	alcohol dehydrogenase
D0819_RS05160	COG0493	'glutamate synthase
D0819_RS05165	COG0070	glutamate synthase
D0819_RS05165	COG0067	glutamate synthase
D0819_RS05165	COG0069	glutamate synthase activity
D0819_RS05170	COG0583	DNA-binding transcription factor activity
D0819_RS05175	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D0819_RS05180	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D0819_RS05190	COG0300	oxidoreductase activity
D0819_RS05195	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
D0819_RS05205	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D0819_RS05210	COG2814	Major facilitator Superfamily
D0819_RS05215	COG1070	Carbohydrate kinase
D0819_RS05220	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D0819_RS05225	COG0243	molybdopterin cofactor binding
D0819_RS05255	COG5278	phosphoserine phosphatase activity
D0819_RS05255	COG0840	transmembrane signaling receptor activity
D0819_RS05260	COG2368	4-hydroxyphenylacetate
D0819_RS05265	COG4305	rare lipoprotein A
D0819_RS05270	COG3619	membrane
D0819_RS05275	COG3866	Pectate lyase
D0819_RS05280	COG2135	peptidase activity
D0819_RS05290	COG2140	Oxalate decarboxylase
D0819_RS05320	COG2720	vancomycin resistance protein
D0819_RS05330	COG3655	Transcriptional regulator
D0819_RS05335	COG3739	integral membrane protein
D0819_RS05340	COG0583	DNA-binding transcription factor activity
D0819_RS05345	COG0697	spore germination
D0819_RS05355	COG0693	protein deglycase activity
D0819_RS05360	COG2367	Beta-lactamase
D0819_RS05380	COG0574	Belongs to the PEP-utilizing enzyme family
D0819_RS05380	COG3848	Pyruvate phosphate dikinase
D0819_RS05385	COG0726	polysaccharide deacetylase
D0819_RS05390	COG2314	TM2 domain
D0819_RS05395	COG1396	sequence-specific DNA binding
D0819_RS05455	COG0457	Tetratricopeptide repeat
D0819_RS05465	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D0819_RS05475	COG4282	regulation of fungal-type cell wall biogenesis
D0819_RS05480	COG1231	oxidoreductase activity
D0819_RS05485	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D0819_RS05490	COG2207	Transcriptional regulator
D0819_RS05490	COG0662	Cupin 2, conserved barrel domain protein
D0819_RS05495	COG0456	acetyltransferase
D0819_RS05500	COG1309	transcriptional regulator
D0819_RS05505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D0819_RS05510	COG3708	Transcriptional regulator
D0819_RS05515	COG2378	regulation of single-species biofilm formation
D0819_RS05525	COG0640	Transcriptional regulator
D0819_RS05530	COG0741	lytic transglycosylase activity
D0819_RS05535	COG2322	membrane
D0819_RS05550	COG1619	proteins homologs of microcin C7 resistance protein MccF
D0819_RS05555	COG3239	Fatty acid desaturase
D0819_RS05560	COG4585	Histidine kinase
D0819_RS05565	COG2197	response regulator
D0819_RS05570	COG3584	3D domain protein
D0819_RS05570	COG1388	LysM domain
D0819_RS05575	COG0514	ATP-dependent DNA helicase (RecQ)
D0819_RS05585	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D0819_RS05590	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D0819_RS05605	COG0071	Belongs to the small heat shock protein (HSP20) family
D0819_RS05630	COG1012	belongs to the aldehyde dehydrogenase family
D0819_RS05635	COG1657	PFAM Prenyltransferase squalene oxidase
D0819_RS05640	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D0819_RS05645	COG0733	neurotransmitter:sodium symporter activity
D0819_RS05650	COG0385	Bile acid
D0819_RS05655	COG0508	dehydrogenase complex catalyzes the overall conversion of
D0819_RS05660	COG0567	Dehydrogenase, E1 component
D0819_RS05665	COG4548	von Willebrand factor, type A
D0819_RS05670	COG0714	Associated with various cellular activities
D0819_RS05675	COG2032	superoxide dismutase activity
D0819_RS05680	COG0791	NLP P60 protein
D0819_RS05680	COG1388	LysM domain
D0819_RS05685	COG1819	glycosyl
D0819_RS05690	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
D0819_RS05695	COG0534	Mate efflux family protein
D0819_RS05700	COG1366	Belongs to the anti-sigma-factor antagonist family
D0819_RS05705	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D0819_RS05710	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D0819_RS05720	COG2962	Rard protein
D0819_RS05735	COG2610	gluconate transmembrane transporter activity
D0819_RS05740	COG1942	4-Oxalocrotonate Tautomerase
D0819_RS05745	COG1733	regulation of RNA biosynthetic process
D0819_RS05750	COG0778	Nitroreductase
D0819_RS05755	COG0400	carboxylic ester hydrolase activity
D0819_RS05760	COG0346	lactoylglutathione lyase activity
D0819_RS05770	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D0819_RS05775	COG0793	Belongs to the peptidase S41A family
D0819_RS05775	COG3409	Peptidoglycan-binding domain 1 protein
D0819_RS05780	COG2226	methyltransferase
D0819_RS05790	COG1876	peptidase activity
D0819_RS05795	COG0813	purine-nucleoside phosphorylase activity
D0819_RS05810	COG0671	phosphoesterase, PA-phosphatase related
D0819_RS05830	COG4479	Belongs to the UPF0346 family
D0819_RS05840	COG1509	lysine 2,3-aminomutase activity
D0819_RS05845	COG0456	acetyltransferase
D0819_RS05850	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D0819_RS05855	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D0819_RS05860	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D0819_RS05865	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D0819_RS05880	COG0456	acetyltransferase
D0819_RS05885	COG0463	Glycosyl transferase, family 2
D0819_RS05900	COG4641	Protein conserved in bacteria
D0819_RS05905	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
D0819_RS05910	COG1086	Polysaccharide biosynthesis protein
D0819_RS05915	COG3331	DNA recombination
D0819_RS05930	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D0819_RS05990	COG0756	dUTP diphosphatase activity
D0819_RS06000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D0819_RS06005	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D0819_RS06015	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D0819_RS06015	COG1372	Participates in initiation and elongation during chromosome replication
D0819_RS06020	COG1780	Probably involved in ribonucleotide reductase function
D0819_RS06085	COG0270	DNA (cytosine-5-)-methyltransferase activity
D0819_RS06100	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
D0819_RS06115	COG3584	3D domain protein
D0819_RS06195	COG2135	peptidase activity
D0819_RS06200	COG1793	dna ligase
D0819_RS06240	COG4474	Belongs to the UPF0398 family
D0819_RS06280	COG3655	Transcriptional regulator
D0819_RS06375	COG3655	Transcriptional regulator
D0819_RS06450	COG0776	regulation of translation
D0819_RS06490	COG4373	Mu-like prophage FluMu protein gp28
D0819_RS06580	COG0582	viral genome integration into host DNA
D0819_RS06605	COG1196	nuclear chromosome segregation
D0819_RS06605	COG0739	heme binding
D0819_RS06605	COG0741	lytic transglycosylase activity
D0819_RS06615	COG2433	Pfam Transposase IS66
D0819_RS06645	COG5632	N-Acetylmuramoyl-L-alanine amidase
D0819_RS06660	COG0457	Tetratricopeptide repeat
D0819_RS06670	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D0819_RS06685	COG2197	response regulator
D0819_RS06690	COG4585	Histidine kinase
D0819_RS06695	COG0730	response to heat
D0819_RS06720	COG5444	nuclease activity
D0819_RS06725	COG4282	regulation of fungal-type cell wall biogenesis
D0819_RS06740	COG1525	nuclease
D0819_RS06760	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D0819_RS06765	COG1086	Polysaccharide biosynthesis protein
D0819_RS06770	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D0819_RS06775	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D0819_RS06780	COG1846	Transcriptional regulator
D0819_RS06785	COG0534	Mate efflux family protein
D0819_RS06795	COG4698	Protein conserved in bacteria
D0819_RS06800	COG2755	lipolytic protein G-D-S-L family
D0819_RS06805	COG1999	signal sequence binding
D0819_RS06815	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D0819_RS06820	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D0819_RS06825	COG1272	protein, Hemolysin III
D0819_RS06830	COG0204	Acyl-transferase
D0819_RS06835	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D0819_RS06840	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D0819_RS06850	COG2136	Putative SAM-dependent methyltransferase
D0819_RS06850	COG2521	methyltransferase
D0819_RS06860	COG0129	dihydroxy-acid dehydratase activity
D0819_RS06865	COG1413	lyase activity
D0819_RS06870	COG1418	mRNA catabolic process
D0819_RS06875	COG0386	Belongs to the glutathione peroxidase family
D0819_RS06880	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
D0819_RS06885	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D0819_RS06895	COG1278	Cold shock
D0819_RS06915	COG0328	RNA-DNA hybrid ribonuclease activity
D0819_RS06920	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
D0819_RS06925	COG0328	RNA-DNA hybrid ribonuclease activity
D0819_RS06935	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D0819_RS06950	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D0819_RS06960	COG1755	Isoprenylcysteine carboxyl methyltransferase
D0819_RS06965	COG3424	synthase
D0819_RS06970	COG2233	PERMEase
D0819_RS06975	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D0819_RS06980	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
D0819_RS06990	COG0800	Aldolase
D0819_RS06995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D0819_RS07000	COG1609	Transcriptional regulator
D0819_RS07005	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
D0819_RS07010	COG1028	Short-chain dehydrogenase reductase Sdr
D0819_RS07015	COG1199	ATP-dependent helicase activity
D0819_RS07030	COG0116	Belongs to the methyltransferase superfamily
D0819_RS07045	COG4474	Belongs to the UPF0398 family
D0819_RS07060	COG3359	exonuclease
D0819_RS07065	COG1205	dead DEAH box helicase
D0819_RS07065	COG1111	helicase
D0819_RS07070	COG2190	(PTS) system
D0819_RS07075	COG0071	Belongs to the small heat shock protein (HSP20) family
D0819_RS07110	COG3331	DNA recombination
D0819_RS07115	COG4499	WXG100 protein secretion system (Wss), protein YukC
D0819_RS07115	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D0819_RS07125	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D0819_RS07130	COG3935	DnaD domain protein
D0819_RS07135	COG0017	Asparaginyl-tRNA synthetase
D0819_RS07140	COG0436	Aminotransferase
D0819_RS07145	COG5353	protein conserved in bacteria
D0819_RS07155	COG1199	ATP-dependent helicase activity
D0819_RS07155	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D0819_RS07160	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
D0819_RS07165	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
D0819_RS07170	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
D0819_RS07175	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
D0819_RS07175	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
D0819_RS07180	COG0617	tRNA 3'-terminal CCA addition
D0819_RS07185	COG0438	transferase activity, transferring glycosyl groups
D0819_RS07190	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D0819_RS07195	COG1803	Methylglyoxal synthase
D0819_RS07200	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
D0819_RS07205	COG1694	Mazg nucleotide pyrophosphohydrolase
D0819_RS07210	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D0819_RS07220	COG4347	Protein of unknown function (DUF1405)
D0819_RS07225	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D0819_RS07225	COG2010	Cytochrome c
D0819_RS07230	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D0819_RS07235	COG0723	plastoquinol--plastocyanin reductase activity
D0819_RS07245	COG5582	Belongs to the UPF0302 family
D0819_RS07250	COG0457	Tetratricopeptide repeat
D0819_RS07255	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
D0819_RS07260	COG0287	Prephenate dehydrogenase
D0819_RS07265	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
D0819_RS07275	COG0133	tryptophan synthase activity
D0819_RS07280	COG0135	phosphoribosylanthranilate isomerase activity
D0819_RS07290	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D0819_RS07295	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D0819_RS07300	COG4401	Chorismate mutase type I
D0819_RS07305	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
D0819_RS07310	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
D0819_RS07315	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
D0819_RS07320	COG0105	UTP biosynthetic process
D0819_RS07325	COG0142	geranyltranstransferase activity
D0819_RS07330	COG2226	methyltransferase
D0819_RS07335	COG0142	geranyltranstransferase activity
D0819_RS07345	COG0302	gtp cyclohydrolase
D0819_RS07350	COG0776	regulation of translation
D0819_RS07355	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D0819_RS07370	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
D0819_RS07375	COG1160	GTP binding
D0819_RS07400	COG1304	FMN binding
D0819_RS07405	COG0539	negative regulation of cytoplasmic translation
D0819_RS07410	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
D0819_RS07420	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
D0819_RS07425	COG2959	enzyme of heme biosynthesis
D0819_RS07430	COG3409	Peptidoglycan-binding domain 1 protein
D0819_RS07430	COG3773	Cell wall hydrolase
D0819_RS07435	COG2339	peptidase activity
D0819_RS07440	COG0492	ferredoxin-NADP+ reductase activity
D0819_RS07445	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D0819_RS07450	COG4862	establishment of competence for transformation
D0819_RS07455	COG1408	metallophosphoesterase
D0819_RS07465	COG1388	LysM domain
D0819_RS07470	COG1266	CAAX protease self-immunity
D0819_RS07475	COG0514	ATP-dependent DNA helicase (RecQ)
D0819_RS07480	COG4955	Helix-turn-helix domain
D0819_RS07485	COG1141	Ferredoxin
D0819_RS07490	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
D0819_RS07495	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D0819_RS07500	COG0710	3-dehydroquinate dehydratase activity
D0819_RS07510	COG1595	DNA-templated transcription, initiation
D0819_RS07515	COG5002	protein histidine kinase activity
D0819_RS07520	COG0745	RESPONSE REGULATOR receiver
D0819_RS07525	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D0819_RS07530	COG1333	cytochrome c biogenesis protein
D0819_RS07535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D0819_RS07540	COG1187	pseudouridine synthase activity
D0819_RS07545	COG0700	Nucleoside recognition
D0819_RS07550	COG2715	membrane protein required for spore maturation
D0819_RS07555	COG1686	Belongs to the peptidase S11 family
D0819_RS07565	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
D0819_RS07570	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
D0819_RS07575	COG1547	Domain of unknown function (DUF309)
D0819_RS07580	COG0456	acetyltransferase
D0819_RS07585	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
D0819_RS07590	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D0819_RS07590	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D0819_RS07595	COG0307	riboflavin synthase, alpha
D0819_RS07600	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D0819_RS07600	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D0819_RS07610	COG0681	Belongs to the peptidase S26 family
D0819_RS07620	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
D0819_RS07630	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D0819_RS07635	COG4086	secreted protein
D0819_RS07640	COG0019	diaminopimelate decarboxylase activity
D0819_RS07645	COG0697	spore germination
D0819_RS07660	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D0819_RS07680	COG1191	sigma factor activity
D0819_RS07685	COG2172	sigma factor antagonist activity
D0819_RS07690	COG1366	Belongs to the anti-sigma-factor antagonist family
D0819_RS07695	COG1686	Belongs to the peptidase S11 family
D0819_RS07700	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
D0819_RS07705	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
D0819_RS07710	COG4974	Belongs to the 'phage' integrase family
D0819_RS07720	COG0735	belongs to the Fur family
D0819_RS07725	COG1300	Membrane
D0819_RS07735	COG0281	malic enzyme
D0819_RS07740	COG1757	Na H antiporter
D0819_RS07745	COG1027	Aspartate ammonia-lyase
D0819_RS07750	COG0252	asparaginase activity
D0819_RS07755	COG1396	sequence-specific DNA binding
D0819_RS07760	COG1379	DNA repair
D0819_RS07765	COG0494	nUDIX hydrolase
D0819_RS07775	COG0667	Aldo Keto reductase
D0819_RS07785	COG1073	alpha beta
D0819_RS07795	COG4918	Iron-sulphur cluster biosynthesis
D0819_RS07800	COG0456	acetyltransferase
D0819_RS07800	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
D0819_RS07805	COG2329	Antibiotic biosynthesis monooxygenase
D0819_RS07810	COG0456	acetyltransferase
D0819_RS07820	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D0819_RS07830	COG2211	Major facilitator Superfamily
D0819_RS07835	COG0346	lactoylglutathione lyase activity
D0819_RS07840	COG1072	(Pantothenic acid kinase))
D0819_RS07845	COG3048	D-serine ammonia-lyase activity
D0819_RS07850	COG0300	oxidoreductase activity
D0819_RS07855	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D0819_RS07860	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D0819_RS07865	COG4187	Peptidase family M20/M25/M40
D0819_RS07870	COG1902	pentaerythritol trinitrate reductase activity
D0819_RS07875	COG0596	Alpha beta hydrolase
D0819_RS07885	COG1234	tRNA 3'-trailer cleavage
D0819_RS07890	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
D0819_RS07895	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D0819_RS07900	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D0819_RS07910	COG0706	membrane insertase activity
D0819_RS07915	COG3361	conserved protein (COG2071)
D0819_RS07920	COG2195	Cleaves the N-terminal amino acid of tripeptides
D0819_RS07925	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D0819_RS07930	COG0346	lactoylglutathione lyase activity
D0819_RS07940	COG1376	ErfK ybiS ycfS ynhG family protein
D0819_RS07945	COG4129	membrane
D0819_RS07950	COG1126	abc transporter atp-binding protein
D0819_RS07955	COG0765	amino acid transport
D0819_RS07960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0819_RS07970	COG1597	lipid kinase activity
D0819_RS07975	COG2814	Major facilitator Superfamily
D0819_RS07980	COG0789	Transcriptional regulator
D0819_RS07980	COG4978	Transcriptional regulator
D0819_RS07985	COG0508	dehydrogenase complex catalyzes the overall conversion of
D0819_RS07990	COG0022	dehydrogenase e1 component
D0819_RS07995	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D0819_RS08000	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D0819_RS08005	COG3426	butyrate kinase activity
D0819_RS08010	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D0819_RS08015	COG0280	phosphate acetyltransferase
D0819_RS08020	COG3290	protein histidine kinase activity
D0819_RS08020	COG3829	transcription factor binding
D0819_RS08030	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
D0819_RS08035	COG2079	MmgE PrpD family protein
D0819_RS08040	COG0372	Belongs to the citrate synthase family
D0819_RS08045	COG1960	acyl-CoA dehydrogenase activity
D0819_RS08050	COG1250	3-hydroxyacyl-CoA dehydrogenase
D0819_RS08055	COG0183	Belongs to the thiolase family
D0819_RS08060	COG0584	glycerophosphoryl diester phosphodiesterase
D0819_RS08065	COG0860	N-Acetylmuramoyl-L-alanine amidase
D0819_RS08080	COG1902	pentaerythritol trinitrate reductase activity
D0819_RS08085	COG0745	RESPONSE REGULATOR receiver
D0819_RS08090	COG0750	zinc metalloprotease
D0819_RS08095	COG0497	DNA recombination
D0819_RS08100	COG1438	arginine binding
D0819_RS08105	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
D0819_RS08110	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
D0819_RS08115	COG0142	geranyltranstransferase activity
D0819_RS08120	COG1722	exodeoxyribonuclease VII activity
D0819_RS08125	COG1570	exodeoxyribonuclease VII activity
D0819_RS08130	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
D0819_RS08135	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D0819_RS08140	COG1302	Protein conserved in bacteria
D0819_RS08145	COG0439	Biotin carboxylase
D0819_RS08150	COG0511	ligase activity, forming carbon-carbon bonds
D0819_RS08190	COG3854	ATPases associated with a variety of cellular activities
D0819_RS08200	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
D0819_RS08205	COG0006	proline dipeptidase activity
D0819_RS08210	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
D0819_RS08220	COG3872	metal-dependent enzyme
D0819_RS08230	COG1752	Esterase of the alpha-beta hydrolase superfamily
D0819_RS08235	COG1321	iron dependent repressor
D0819_RS08240	COG0095	Lipoate-protein ligase
D0819_RS08245	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D0819_RS08250	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D0819_RS08255	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D0819_RS08260	COG0404	The glycine cleavage system catalyzes the degradation of glycine
D0819_RS08265	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D0819_RS08280	COG1396	sequence-specific DNA binding
D0819_RS08290	COG0681	Belongs to the peptidase S26 family
D0819_RS08315	COG4940	Competence protein ComGF
D0819_RS08325	COG4970	Tfp pilus assembly protein FimT
D0819_RS08330	COG4537	Required for transformation and DNA binding
D0819_RS08335	COG1459	type II secretion system
D0819_RS08340	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D0819_RS08350	COG0598	Magnesium transport protein CorA
D0819_RS08355	COG1253	flavin adenine dinucleotide binding
D0819_RS08360	COG1366	Belongs to the anti-sigma-factor antagonist family
D0819_RS08370	COG1393	Belongs to the ArsC family
D0819_RS08380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D0819_RS08390	COG0011	TIGRFAM Protein of
D0819_RS08400	COG2866	Carboxypeptidase
D0819_RS08405	COG1368	sulfuric ester hydrolase activity
D0819_RS08410	COG1940	carbohydrate kinase activity
D0819_RS08415	COG4483	Protein conserved in bacteria
D0819_RS08420	COG0705	Rhomboid family
D0819_RS08420	COG0457	Tetratricopeptide repeat
D0819_RS08430	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D0819_RS08440	COG0438	transferase activity, transferring glycosyl groups
D0819_RS08455	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D0819_RS08460	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D0819_RS08465	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D0819_RS08470	COG0581	inorganic phosphate transmembrane transporter activity
D0819_RS08475	COG0573	inorganic phosphate transmembrane transporter activity
D0819_RS08480	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D0819_RS08485	COG0768	penicillin binding
D0819_RS08490	COG0477	Major facilitator Superfamily
D0819_RS08495	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D0819_RS08500	COG2839	Protein conserved in bacteria
D0819_RS08505	COG5521	maltodextrose utilization protein MalA
D0819_RS08510	COG1388	LysM domain
D0819_RS08515	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
D0819_RS08520	COG4709	membrane
D0819_RS08525	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
D0819_RS08530	COG0735	belongs to the Fur family
D0819_RS08535	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D0819_RS08545	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
D0819_RS08550	COG0513	Belongs to the DEAD box helicase family
D0819_RS08560	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
D0819_RS08565	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
D0819_RS08570	COG2384	SAM-dependent methyltransferase
D0819_RS08575	COG2010	Cytochrome c
D0819_RS08580	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D0819_RS08585	COG0358	DNA primase activity
D0819_RS08590	COG1671	Belongs to the UPF0178 family
D0819_RS08595	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
D0819_RS08600	COG0517	IMP dehydrogenase activity
D0819_RS08605	COG0751	glycine-tRNA ligase activity
D0819_RS08610	COG0752	glycyl-tRNA synthetase alpha subunit
D0819_RS08615	COG1381	Involved in DNA repair and RecF pathway recombination
D0819_RS08625	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
D0819_RS08630	COG0295	cytidine deaminase activity
D0819_RS08635	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
D0819_RS08640	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
D0819_RS08645	COG1480	7TM receptor with intracellular HD hydrolase
D0819_RS08650	COG1702	phosphate starvation-inducible protein PhoH
D0819_RS08655	COG0561	phosphatase activity
D0819_RS08670	COG4864	UPF0365 protein
D0819_RS08675	COG1030	water channel activity
D0819_RS08680	COG1610	YqeY-like protein
D0819_RS08690	COG1283	sodium-dependent phosphate transmembrane transporter activity
D0819_RS08695	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D0819_RS08700	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D0819_RS08705	COG2264	protein methyltransferase activity
D0819_RS08710	COG0484	heat shock protein binding
D0819_RS08715	COG0443	Heat shock 70 kDa protein
D0819_RS08720	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
D0819_RS08725	COG1420	regulation of RNA biosynthetic process
D0819_RS08730	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D0819_RS08735	COG0481	GTPase activity
D0819_RS08745	COG0860	N-Acetylmuramoyl-L-alanine amidase
D0819_RS08750	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
D0819_RS08755	COG0268	Binds directly to 16S ribosomal RNA
D0819_RS08760	COG1466	dna polymerase III delta subunit
D0819_RS08775	COG2333	competence protein COMEC
D0819_RS08775	COG0658	competence protein
D0819_RS08780	COG2131	deaminase
D0819_RS08785	COG1555	photosystem II stabilization
D0819_RS08785	COG1596	polysaccharide export
D0819_RS08790	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D0819_RS08795	COG2226	methyltransferase
D0819_RS08800	COG0799	negative regulation of ribosome biogenesis
D0819_RS08805	COG1713	HD superfamily hydrolase involved in NAD metabolism
D0819_RS08810	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
D0819_RS08815	COG1534	Rna-binding protein
D0819_RS08820	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D0819_RS08825	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D0819_RS08830	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
D0819_RS08840	COG2755	lipolytic protein G-D-S-L family
D0819_RS08845	COG5632	N-Acetylmuramoyl-L-alanine amidase
D0819_RS08845	COG3409	Peptidoglycan-binding domain 1 protein
D0819_RS08850	COG0398	Pfam SNARE associated Golgi protein
D0819_RS08855	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
D0819_RS08865	COG3209	COG3209 Rhs family protein
D0819_RS08880	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D0819_RS08890	COG3223	Belongs to the PsiE family
D0819_RS08895	COG5002	protein histidine kinase activity
D0819_RS08895	COG0642	Histidine kinase
D0819_RS08900	COG0745	RESPONSE REGULATOR receiver
D0819_RS08905	COG2311	Membrane
D0819_RS08915	COG0454	-acetyltransferase
D0819_RS08920	COG2249	NAD(P)H dehydrogenase (quinone) activity
D0819_RS08930	COG0730	response to heat
D0819_RS08935	COG0425	Belongs to the sulfur carrier protein TusA family
D0819_RS08940	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D0819_RS08940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D0819_RS08950	COG0425	Belongs to the sulfur carrier protein TusA family
D0819_RS08950	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D0819_RS08955	COG1054	Belongs to the UPF0176 family
D0819_RS08960	COG2210	Belongs to the sulfur carrier protein TusA family
D0819_RS08965	COG1937	Protein conserved in bacteria
D0819_RS08970	COG0662	Cupin 2, conserved barrel domain protein
D0819_RS08980	COG0789	Transcriptional regulator
D0819_RS08980	COG4978	Transcriptional regulator
D0819_RS08985	COG2814	Major facilitator Superfamily
D0819_RS08990	COG0456	acetyltransferase
D0819_RS08995	COG1253	flavin adenine dinucleotide binding
D0819_RS09005	COG0697	spore germination
D0819_RS09010	COG0583	DNA-binding transcription factor activity
D0819_RS09015	COG2072	flavoprotein involved in K transport
D0819_RS09020	COG1230	cation diffusion facilitator family transporter
D0819_RS09030	COG1114	Component of the transport system for branched-chain amino acids
D0819_RS09035	COG1687	branched-chain amino acid
D0819_RS09040	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
D0819_RS09045	COG1522	sequence-specific DNA binding
D0819_RS09050	COG2732	(Barnase) inhibitor
D0819_RS09055	COG2124	cytochrome p450
D0819_RS09060	COG1335	isochorismatase
D0819_RS09075	COG2318	DinB family
D0819_RS09085	COG2070	2-Nitropropane dioxygenase
D0819_RS09090	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
D0819_RS09110	COG4978	Transcriptional regulator
D0819_RS09110	COG0789	Transcriptional regulator
D0819_RS09115	COG2315	Protein conserved in bacteria
D0819_RS09125	COG3443	Belongs to the bacterial solute-binding protein 9 family
D0819_RS09130	COG1595	DNA-templated transcription, initiation
D0819_RS09135	COG0667	Aldo Keto reductase
D0819_RS09140	COG2851	Citrate transporter
D0819_RS09145	COG0583	DNA-binding transcription factor activity
D0819_RS09150	COG2828	Protein conserved in bacteria
D0819_RS09155	COG3409	Peptidoglycan-binding domain 1 protein
D0819_RS09160	COG5566	PFAM Mor transcription activator
D0819_RS09165	COG0596	Alpha beta hydrolase
D0819_RS09170	COG4991	sh3 domain protein
D0819_RS09175	COG4991	sh3 domain protein
D0819_RS09185	COG0346	lactoylglutathione lyase activity
D0819_RS09195	COG5577	PFAM Coat F domain
D0819_RS09200	COG1063	alcohol dehydrogenase
D0819_RS09210	COG5577	PFAM Coat F domain
D0819_RS09215	COG0789	Transcriptional regulator
D0819_RS09225	COG1064	alcohol dehydrogenase
D0819_RS09230	COG0693	protein deglycase activity
D0819_RS09235	COG1621	beta-fructofuranosidase activity
D0819_RS09240	COG3716	PTS system mannose fructose sorbose family IID component
D0819_RS09245	COG3715	PTS system
D0819_RS09250	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0819_RS09255	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0819_RS09260	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D0819_RS09260	COG3933	PFAM sigma-54 factor interaction domain-containing protein
D0819_RS09270	COG1113	amino acid transport
D0819_RS09275	COG1280	lysine exporter protein (LysE YggA)
D0819_RS09280	COG1378	Sugar-specific transcriptional regulator TrmB
D0819_RS09285	COG1595	DNA-templated transcription, initiation
D0819_RS09295	COG2755	lipolytic protein G-D-S-L family
D0819_RS09295	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
D0819_RS09305	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D0819_RS09305	COG2124	cytochrome p450
D0819_RS09310	COG1309	transcriptional regulator
D0819_RS09315	COG2226	methyltransferase
D0819_RS09330	COG2116	formate transmembrane transporter activity
D0819_RS09335	COG5609	conserved protein (DUF2294)
D0819_RS09340	COG3383	formate dehydrogenase (NAD+) activity
D0819_RS09345	COG2427	Protein of unknown function (DUF1641)
D0819_RS09355	COG0626	cystathionine gamma-synthase activity
D0819_RS09360	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D0819_RS09365	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
D0819_RS09370	COG2226	methyltransferase
D0819_RS09385	COG0768	penicillin binding
D0819_RS09390	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D0819_RS09395	COG0572	uridine kinase
D0819_RS09400	COG0826	peptidase U32
D0819_RS09405	COG0826	peptidase U32
D0819_RS09410	COG4122	O-methyltransferase activity
D0819_RS09415	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D0819_RS09420	COG3906	Belongs to the UPF0473 family
D0819_RS09425	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
D0819_RS09430	COG4472	Bacterial protein of unknown function (DUF965)
D0819_RS09435	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
D0819_RS09440	COG0628	permease
D0819_RS09445	COG1126	abc transporter atp-binding protein
D0819_RS09450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0819_RS09455	COG0765	amino acid transport
D0819_RS09460	COG0765	amino acid transport
D0819_RS09475	COG3881	PFAM PRC-barrel domain
D0819_RS09480	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D0819_RS09485	COG0457	Tetratricopeptide repeat
D0819_RS09490	COG0482	sulfurtransferase activity
D0819_RS09495	COG1104	cysteine desulfurase activity
D0819_RS09500	COG1959	2 iron, 2 sulfur cluster binding
D0819_RS09505	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D0819_RS09510	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
D0819_RS09520	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
D0819_RS09525	COG0124	histidyl-tRNA synthetase
D0819_RS09535	COG0860	N-Acetylmuramoyl-L-alanine amidase
D0819_RS09535	COG3103	Sh3 type 3 domain protein
D0819_RS09535	COG4991	sh3 domain protein
D0819_RS09540	COG1490	D-aminoacyl-tRNA deacylase activity
D0819_RS09545	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D0819_RS09550	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D0819_RS09555	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
D0819_RS09555	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D0819_RS09560	COG5416	Lipopolysaccharide assembly protein A domain
D0819_RS09565	COG0490	domain, Protein
D0819_RS09570	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D0819_RS09570	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D0819_RS09580	COG2244	polysaccharide biosynthetic process
D0819_RS09585	COG2323	membrane
D0819_RS09595	COG1862	Preprotein translocase
D0819_RS09600	COG0343	queuine tRNA-ribosyltransferase activity
D0819_RS09605	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
D0819_RS09615	COG2255	four-way junction helicase activity
D0819_RS09620	COG0632	four-way junction helicase activity
D0819_RS09630	COG2814	Major facilitator Superfamily
D0819_RS09635	COG0673	inositol 2-dehydrogenase activity
D0819_RS09640	COG2112	serine threonine protein kinase
D0819_RS09660	COG1115	amino acid carrier protein
D0819_RS09665	COG0217	transcriptional regulatory protein
D0819_RS09675	COG1388	LysM domain
D0819_RS09680	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
D0819_RS09685	COG0157	Belongs to the NadC ModD family
D0819_RS09690	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
D0819_RS09695	COG1104	cysteine desulfurase activity
D0819_RS09700	COG1827	regulation of RNA biosynthetic process
D0819_RS09705	COG0077	Prephenate dehydratase
D0819_RS09710	COG4492	Belongs to the UPF0735 family
D0819_RS09715	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
D0819_RS09720	COG3290	protein histidine kinase activity
D0819_RS09730	COG0211	Belongs to the bacterial ribosomal protein bL27 family
D0819_RS09735	COG2868	ribosomal protein
D0819_RS09740	COG0261	This protein binds to 23S rRNA in the presence of protein L20
D0819_RS09745	COG1994	Peptidase M50
D0819_RS09750	COG0739	heme binding
D0819_RS09755	COG2894	cell division
D0819_RS09760	COG0850	regulation of cytokinetic process
D0819_RS09765	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
D0819_RS09775	COG1077	Cell shape determining protein MreB Mrl
D0819_RS09780	COG2003	Belongs to the UPF0758 family
D0819_RS09785	COG0424	maF-like protein
D0819_RS09795	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
D0819_RS09800	COG0285	dihydrofolate synthase activity
D0819_RS09805	COG0525	valine-tRNA ligase activity
D0819_RS09815	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D0819_RS09820	COG1388	LysM domain
D0819_RS09825	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D0819_RS09830	COG0113	porphobilinogen synthase activity
D0819_RS09835	COG1587	Uroporphyrinogen-III synthase
D0819_RS09840	COG0181	hydroxymethylbilane synthase activity
D0819_RS09845	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D0819_RS09850	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
D0819_RS09860	COG0218	Necessary for normal cell division and for the maintenance of normal septation
D0819_RS09865	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
D0819_RS09870	COG1067	ATP-dependent peptidase activity
D0819_RS09870	COG0470	DNA polymerase III
D0819_RS09875	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
D0819_RS09880	COG0544	peptidyl-prolyl cis-trans isomerase activity
D0819_RS09885	COG1477	protein flavinylation
D0819_RS09885	COG0457	Tetratricopeptide repeat
D0819_RS09890	COG0066	3-isopropylmalate dehydratase activity
D0819_RS09895	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
D0819_RS09900	COG0473	3-isopropylmalate dehydrogenase activity
D0819_RS09905	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D0819_RS09910	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
D0819_RS09915	COG0440	acetolactate synthase activity
D0819_RS09920	COG0028	Belongs to the TPP enzyme family
D0819_RS09930	COG0454	-acetyltransferase
D0819_RS09935	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
D0819_RS09945	COG0622	Phosphoesterase
D0819_RS09950	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
D0819_RS09955	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
D0819_RS09960	COG5401	PFAM Sporulation and spore germination
D0819_RS09965	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
D0819_RS09970	COG1846	Transcriptional regulator
D0819_RS09975	COG2197	response regulator
D0819_RS09980	COG0824	Thioesterase
D0819_RS09985	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D0819_RS09990	COG1053	succinate dehydrogenase
D0819_RS09995	COG2009	succinate dehydrogenase
D0819_RS10000	COG1719	4-vinyl reductase, 4VR
D0819_RS10005	COG0527	aspartate kinase activity
D0819_RS10010	COG0322	excinuclease ABC activity
D0819_RS10015	COG3118	belongs to the thioredoxin family
D0819_RS10020	COG3534	alpha-L-arabinofuranosidase
D0819_RS10025	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
D0819_RS10030	COG2086	electron transfer activity
D0819_RS10035	COG1024	Enoyl-CoA hydratase
D0819_RS10040	COG1309	transcriptional regulator
D0819_RS10045	COG0318	PFAM AMP-dependent synthetase and ligase
D0819_RS10050	COG3766	membrane
D0819_RS10055	COG1193	negative regulation of DNA recombination
D0819_RS10060	COG1796	DNA polymerase
D0819_RS10060	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D0819_RS10065	COG1286	toxin biosynthetic process
D0819_RS10070	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
D0819_RS10075	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
D0819_RS10080	COG0072	phenylalanine-tRNA ligase activity
D0819_RS10080	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D0819_RS10085	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
D0819_RS10095	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D0819_RS10105	COG3835	regulator
D0819_RS10110	COG0277	FAD linked oxidase domain protein
D0819_RS10115	COG0247	lactate metabolic process
D0819_RS10120	COG0346	lactoylglutathione lyase activity
D0819_RS10130	COG1966	Carbon starvation protein
D0819_RS10135	COG3534	alpha-L-arabinofuranosidase
D0819_RS10140	COG0395	ABC-type sugar transport system, permease component
D0819_RS10145	COG1175	transmembrane transport
D0819_RS10150	COG1653	transport
D0819_RS10155	COG0371	Dehydrogenase
D0819_RS10160	COG0647	UMP catabolic process
D0819_RS10165	COG0235	Class ii aldolase
D0819_RS10170	COG1069	ribulokinase activity
D0819_RS10175	COG2160	L-arabinose isomerase activity
D0819_RS10180	COG3507	Belongs to the glycosyl hydrolase 43 family
D0819_RS10185	COG1363	Peptidase, m42
D0819_RS10195	COG3326	Membrane
D0819_RS10200	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
D0819_RS10205	COG0291	Belongs to the bacterial ribosomal protein bL35 family
D0819_RS10210	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
D0819_RS10220	COG1346	cytolysis
D0819_RS10225	COG1380	Effector of murein hydrolase LrgA
D0819_RS10230	COG3279	Response regulator of the LytR AlgR family
D0819_RS10235	COG3275	phosphorelay sensor kinase activity
D0819_RS10240	COG1011	Hydrolase
D0819_RS10245	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D0819_RS10255	COG0398	Pfam SNARE associated Golgi protein
D0819_RS10260	COG1484	DNA-dependent DNA replication
D0819_RS10265	COG3611	Membrane attachment protein
D0819_RS10270	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
D0819_RS10275	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
D0819_RS10280	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D0819_RS10285	COG1733	regulation of RNA biosynthetic process
D0819_RS10295	COG0656	L-ascorbic acid biosynthetic process
D0819_RS10300	COG0237	dephospho-CoA kinase activity
D0819_RS10305	COG1971	Probably functions as a manganese efflux pump
D0819_RS10310	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D0819_RS10315	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D0819_RS10315	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D0819_RS10320	COG5002	protein histidine kinase activity
D0819_RS10325	COG0745	RESPONSE REGULATOR receiver
D0819_RS10330	COG0039	L-malate dehydrogenase activity
D0819_RS10335	COG0538	isocitrate dehydrogenase activity
D0819_RS10340	COG0372	Belongs to the citrate synthase family
D0819_RS10345	COG2707	UPF0756 membrane protein
D0819_RS10350	COG0628	permease
D0819_RS10355	COG3030	protein affecting phage T7 exclusion by the F plasmid
D0819_RS10360	COG0469	pyruvate kinase activity
D0819_RS10365	COG0205	6-phosphofructokinase activity
D0819_RS10370	COG0825	malonyl-CoA metabolic process
D0819_RS10375	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
D0819_RS10380	COG0281	malic enzyme
D0819_RS10385	COG0587	DNA-directed DNA polymerase activity
D0819_RS10405	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
D0819_RS10415	COG4109	DRTGG domain
D0819_RS10420	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
D0819_RS10425	COG1028	Short-chain dehydrogenase reductase Sdr
D0819_RS10435	COG0165	Argininosuccinate lyase
D0819_RS10440	COG0137	argininosuccinate synthase activity
D0819_RS10445	COG0521	Mo-molybdopterin cofactor biosynthetic process
D0819_RS10450	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
D0819_RS10460	COG0827	DNA restriction-modification system
D0819_RS10465	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
D0819_RS10470	COG3874	Sporulation protein YtfJ
D0819_RS10480	COG1714	RDD family
D0819_RS10485	COG0616	signal peptide processing
D0819_RS10490	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D0819_RS10495	COG1574	metal-dependent hydrolase with the TIM-barrel fold
D0819_RS10500	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D0819_RS10510	COG0301	tRNA thio-modification
D0819_RS10515	COG1104	cysteine desulfurase activity
D0819_RS10520	COG1114	Component of the transport system for branched-chain amino acids
D0819_RS10525	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
D0819_RS10530	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D0819_RS10535	COG1309	transcriptional regulator
D0819_RS10540	COG1956	GAF domain-containing protein
D0819_RS10545	COG2199	diguanylate cyclase activity
D0819_RS10545	COG2203	Gaf domain
D0819_RS10555	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
D0819_RS10560	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D0819_RS10565	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D0819_RS10570	COG0454	-acetyltransferase
D0819_RS10575	COG0517	IMP dehydrogenase activity
D0819_RS10580	COG0123	including yeast histone deacetylase and acetoin utilization protein
D0819_RS10585	COG1360	Flagellar Motor Protein
D0819_RS10590	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D0819_RS10595	COG1609	Transcriptional regulator
D0819_RS10600	COG1605	Chorismate mutase
D0819_RS10600	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
D0819_RS10605	COG3118	belongs to the thioredoxin family
D0819_RS10610	COG4980	gas vesicle protein
D0819_RS10615	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
D0819_RS10620	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
D0819_RS10625	COG1674	ftsk spoiiie
D0819_RS10630	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D0819_RS10635	COG4848	Belongs to the UPF0354 family
D0819_RS10640	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D0819_RS10655	COG1363	Peptidase, m42
D0819_RS10660	COG5584	Small secreted protein
D0819_RS10665	COG0281	malic enzyme
D0819_RS10670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D0819_RS10675	COG0220	tRNA (guanine-N7-)-methyltransferase activity
D0819_RS10685	COG0510	thiamine kinase activity
D0819_RS10690	COG1523	belongs to the glycosyl hydrolase 13 family
D0819_RS10695	COG1597	lipid kinase activity
D0819_RS10705	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
D0819_RS10710	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D0819_RS10715	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D0819_RS10720	COG2252	PERMEase
D0819_RS10725	COG4473	ABC transporter
D0819_RS10730	COG1131	(ABC) transporter
D0819_RS10735	COG1349	DNA-binding transcription factor activity
D0819_RS10740	COG1187	pseudouridine synthase activity
D0819_RS10745	COG2244	polysaccharide biosynthetic process
D0819_RS10750	COG2081	HI0933 family
D0819_RS10755	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D0819_RS10765	COG5578	integral membrane protein
D0819_RS10770	COG0673	inositol 2-dehydrogenase activity
D0819_RS10775	COG1653	transport
D0819_RS10780	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
D0819_RS10785	COG4209	transmembrane transport
D0819_RS10790	COG2207	Transcriptional regulator
D0819_RS10795	COG1653	transport
D0819_RS10800	COG0395	ABC-type sugar transport system, permease component
D0819_RS10805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D0819_RS10810	COG2124	cytochrome p450
D0819_RS10815	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
D0819_RS10825	COG0156	8-amino-7-oxononanoate synthase activity
D0819_RS10830	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D0819_RS10840	COG1073	alpha beta
D0819_RS10845	COG1609	Transcriptional regulator
D0819_RS10850	COG1653	transport
D0819_RS10855	COG1175	transmembrane transport
D0819_RS10860	COG0395	ABC-type sugar transport system, permease component
D0819_RS10865	COG1486	melibiose metabolic process
D0819_RS10870	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D0819_RS10875	COG0495	leucyl-tRNA aminoacylation
D0819_RS10885	COG1366	Belongs to the anti-sigma-factor antagonist family
D0819_RS10885	COG2202	Pas domain
D0819_RS10890	COG2814	Major facilitator Superfamily
D0819_RS10895	COG2433	Pfam Transposase IS66
D0819_RS10900	COG0577	efflux transmembrane transporter activity
D0819_RS10905	COG1136	(ABC) transporter
D0819_RS10910	COG2205	protein histidine kinase activity
D0819_RS10915	COG0745	RESPONSE REGULATOR receiver
D0819_RS10920	COG0577	efflux transmembrane transporter activity
D0819_RS10925	COG1136	(ABC) transporter
D0819_RS10940	COG1131	(ABC) transporter
D0819_RS10945	COG1725	Transcriptional regulator
D0819_RS10960	COG1242	4 iron, 4 sulfur cluster binding
D0819_RS10965	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
D0819_RS10975	COG2267	carboxylic ester hydrolase activity
D0819_RS10980	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D0819_RS10985	COG1113	amino acid transport
D0819_RS10990	COG0367	asparagine synthase
D0819_RS10995	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
D0819_RS11000	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
D0819_RS11010	COG1506	peptidase
D0819_RS11015	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D0819_RS11020	COG1116	anion transmembrane transporter activity
D0819_RS11025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D0819_RS11030	COG0494	nUDIX hydrolase
D0819_RS11035	COG4824	toxin secretion phage lysis holin
D0819_RS11040	COG0783	Belongs to the Dps family
D0819_RS11055	COG1854	S-ribosylhomocysteine lyase activity
D0819_RS11060	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
D0819_RS11065	COG0288	reversible hydration of carbon dioxide
D0819_RS11070	COG0254	rRNA binding
D0819_RS11075	COG1271	oxidase subunit
D0819_RS11080	COG1294	oxidase, subunit
D0819_RS11090	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D0819_RS11095	COG1321	iron dependent repressor
D0819_RS11095	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D0819_RS11100	COG1121	(ABC) transporter
D0819_RS11105	COG0803	Belongs to the bacterial solute-binding protein 9 family
D0819_RS11110	COG4948	Mandelate Racemase Muconate Lactonizing
D0819_RS11115	COG0318	PFAM AMP-dependent synthetase and ligase
D0819_RS11120	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
D0819_RS11125	COG0596	Alpha beta hydrolase
D0819_RS11130	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
D0819_RS11135	COG1169	isochorismate synthase
D0819_RS11140	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D0819_RS11145	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D0819_RS11150	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D0819_RS11155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D0819_RS11160	COG0438	transferase activity, transferring glycosyl groups
D0819_RS11170	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D0819_RS11175	COG0438	transferase activity, transferring glycosyl groups
D0819_RS11180	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D0819_RS11185	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
D0819_RS11190	COG0058	SHG alpha-glucan phosphorylase activity
D0819_RS11195	COG0297	glycogen (starch) synthase activity
D0819_RS11200	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D0819_RS11205	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D0819_RS11210	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
D0819_RS11335	COG3859	Proton-coupled thiamine transporter YuaJ
D0819_RS11340	COG1247	-acetyltransferase
D0819_RS11345	COG2268	Band 7 protein
D0819_RS11350	COG1585	Membrane protein implicated in regulation of membrane protease activity
D0819_RS11355	COG2318	DinB family
D0819_RS11365	COG1454	alcohol dehydrogenase
D0819_RS11370	COG1012	belongs to the aldehyde dehydrogenase family
D0819_RS11375	COG1510	regulation of RNA biosynthetic process
D0819_RS11385	COG0569	domain protein
D0819_RS11390	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D0819_RS11395	COG4682	membrane
D0819_RS11400	COG1705	Flagellar rod assembly protein muramidase FlgJ
D0819_RS11405	COG0477	Major facilitator Superfamily
D0819_RS11410	COG5553	Cysteine dioxygenase type I
D0819_RS11420	COG1968	undecaprenyl-diphosphatase activity
D0819_RS11425	COG0628	permease
D0819_RS11430	COG0673	inositol 2-dehydrogenase activity
D0819_RS11435	COG4806	L-rhamnose isomerase
D0819_RS11440	COG3254	rhamnose metabolic process
D0819_RS11445	COG1070	Carbohydrate kinase
D0819_RS11450	COG1349	DNA-binding transcription factor activity
D0819_RS11455	COG3347	Dehydrogenase
D0819_RS11455	COG1028	Short-chain dehydrogenase reductase Sdr
D0819_RS11460	COG0840	transmembrane signaling receptor activity
D0819_RS11465	COG0840	transmembrane signaling receptor activity
D0819_RS11470	COG0840	transmembrane signaling receptor activity
D0819_RS11475	COG0840	transmembrane signaling receptor activity
D0819_RS11490	COG0432	Pfam Uncharacterised protein family UPF0047
D0819_RS11500	COG0366	Alpha amylase catalytic
D0819_RS11505	COG1253	flavin adenine dinucleotide binding
D0819_RS11510	COG2738	Putative neutral zinc metallopeptidase
D0819_RS11525	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D0819_RS11540	COG0166	Belongs to the GPI family
D0819_RS11545	COG1979	alcohol dehydrogenase
D0819_RS11550	COG1979	alcohol dehydrogenase
D0819_RS11555	COG2155	Conserved Protein
D0819_RS11560	COG1098	S1 RNA binding domain
D0819_RS11565	COG0436	Aminotransferase
D0819_RS11570	COG1522	sequence-specific DNA binding
D0819_RS11575	COG2267	carboxylic ester hydrolase activity
D0819_RS11585	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
D0819_RS11590	COG2205	protein histidine kinase activity
D0819_RS11600	COG5018	Exonuclease
D0819_RS11610	COG2814	Major facilitator Superfamily
D0819_RS11615	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D0819_RS11620	COG3011	Protein conserved in bacteria
D0819_RS11630	COG3290	protein histidine kinase activity
D0819_RS11635	COG4565	transcriptional regulatory protein
D0819_RS11640	COG1744	ABC transporter substrate-binding protein PnrA-like
D0819_RS11645	COG3845	ABC transporter
D0819_RS11650	COG4603	Belongs to the binding-protein-dependent transport system permease family
D0819_RS11655	COG1079	Belongs to the binding-protein-dependent transport system permease family
D0819_RS11660	COG3493	citrate carrier protein
D0819_RS11670	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D0819_RS11670	COG2111	Na H antiporter
D0819_RS11675	COG2111	Na H antiporter
D0819_RS11680	COG1006	Multisubunit Na H antiporter MnhC subunit
D0819_RS11685	COG0651	ATP synthesis coupled electron transport
D0819_RS11690	COG1863	multisubunit Na H antiporter MnhE subunit
D0819_RS11695	COG2212	antiporter activity
D0819_RS11700	COG1320	monovalent cation:proton antiporter activity
D0819_RS11705	COG2050	protein possibly involved in aromatic compounds catabolism
D0819_RS11710	COG2197	response regulator
D0819_RS11725	COG0142	geranyltranstransferase activity
D0819_RS11740	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
D0819_RS11745	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
D0819_RS11750	COG1335	isochorismatase
D0819_RS11755	COG5506	Protein of unknown function (DUF1694)
D0819_RS11770	COG0628	permease
D0819_RS11785	COG1418	mRNA catabolic process
D0819_RS11790	COG1028	Short-chain dehydrogenase reductase Sdr
D0819_RS11800	COG1511	domain protein
D0819_RS11805	COG1674	ftsk spoiiie
D0819_RS11805	COG0433	COG0433 Predicted ATPase
D0819_RS11810	COG4499	WXG100 protein secretion system (Wss), protein YukC
D0819_RS11815	COG5417	Belongs to the EsaB family
D0819_RS11820	COG4842	Belongs to the WXG100 family
D0819_RS11825	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
D0819_RS11825	COG2508	Transcriptional regulator
D0819_RS11830	COG0686	Belongs to the AlaDH PNT family
D0819_RS11835	COG5634	Uncharacterized conserved protein (DUF2278)
D0819_RS11840	COG3251	PFAM MbtH domain protein
D0819_RS11845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0819_RS11850	COG1535	isochorismatase
D0819_RS11850	COG3433	isochorismatase activity
D0819_RS11855	COG1021	2,3-dihydroxybenzoate-AMP ligase
D0819_RS11860	COG1169	isochorismate synthase
D0819_RS11865	COG1028	Short-chain dehydrogenase reductase Sdr
D0819_RS11870	COG2819	hydrolase of the alpha beta superfamily
D0819_RS11875	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D0819_RS11880	COG1268	BioY protein
D0819_RS11885	COG2056	Na+-H+ antiporter family
D0819_RS11890	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
D0819_RS11895	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
D0819_RS11900	COG3584	3D domain protein
D0819_RS11915	COG1252	NADH dehydrogenase
D0819_RS11920	COG0492	ferredoxin-NADP+ reductase activity
D0819_RS11930	COG0516	GMP reductase activity
D0819_RS11945	COG1131	(ABC) transporter
D0819_RS11965	COG2808	Putative FMN-binding domain
D0819_RS11970	COG0456	acetyltransferase
D0819_RS11975	COG0316	Belongs to the HesB IscA family
D0819_RS11980	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
D0819_RS11985	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D0819_RS11990	COG4844	belongs to the
D0819_RS11995	COG1252	NADH dehydrogenase
D0819_RS12000	COG4837	Protein of unknown function (DUF1462)
D0819_RS12005	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
D0819_RS12010	COG4946	Tricorn protease homolog
D0819_RS12010	COG1506	peptidase
D0819_RS12010	COG0823	Involved in the tonB-independent uptake of proteins
D0819_RS12015	COG0083	homoserine kinase activity
D0819_RS12020	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
D0819_RS12025	COG0460	homoserine dehydrogenase
D0819_RS12030	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D0819_RS12035	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D0819_RS12040	COG0647	UMP catabolic process
D0819_RS12045	COG2445	Protein of unknown function DUF86
D0819_RS12050	COG4470	Protein conserved in bacteria
D0819_RS12060	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
D0819_RS12065	COG0739	heme binding
D0819_RS12075	COG3377	Domain of unknown function (DUF1805)
D0819_RS12080	COG0737	Belongs to the 5'-nucleotidase family
D0819_RS12085	COG0730	response to heat
D0819_RS12090	COG1801	Protein of unknown function DUF72
D0819_RS12100	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D0819_RS12105	COG2508	Transcriptional regulator
D0819_RS12110	COG2233	PERMEase
D0819_RS12115	COG2233	PERMEase
D0819_RS12120	COG3195	allantoin biosynthetic process
D0819_RS12120	COG3648	Uricase
D0819_RS12125	COG2351	hydroxyisourate hydrolase activity
D0819_RS12135	COG2080	2 iron, 2 sulfur cluster binding
D0819_RS12140	COG1529	Aldehyde oxidase and xanthine dehydrogenase
D0819_RS12145	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
D0819_RS12150	COG2068	MobA-Related Protein
D0819_RS12155	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
D0819_RS12160	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
D0819_RS12165	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D0819_RS12175	COG2356	endonuclease I
D0819_RS12180	COG3842	ATPase activity
D0819_RS12185	COG2188	Transcriptional regulator
D0819_RS12190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D0819_RS12195	COG0395	ABC-type sugar transport system, permease component
D0819_RS12200	COG1175	transmembrane transport
D0819_RS12205	COG1653	transport
D0819_RS12210	COG2222	sugar isomerase
D0819_RS12215	COG0322	excinuclease ABC activity
D0819_RS12220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D0819_RS12235	COG0346	lactoylglutathione lyase activity
D0819_RS12240	COG0640	Transcriptional regulator
D0819_RS12245	COG0719	Fe-S assembly protein
D0819_RS12250	COG0822	iron-sulfur transferase activity
D0819_RS12255	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D0819_RS12260	COG0719	Fe-S assembly protein
D0819_RS12265	COG0396	ATPase activity
D0819_RS12275	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D0819_RS12280	COG1464	Belongs to the NlpA lipoprotein family
D0819_RS12285	COG2011	ABC-type metal ion transport system permease component
D0819_RS12290	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D0819_RS12300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D0819_RS12305	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
D0819_RS12315	COG0509	glycine decarboxylation via glycine cleavage system
D0819_RS12320	COG1393	Belongs to the ArsC family
D0819_RS12325	COG1960	acyl-CoA dehydrogenase activity
D0819_RS12330	COG0183	Belongs to the thiolase family
D0819_RS12335	COG1250	3-hydroxyacyl-CoA dehydrogenase
D0819_RS12335	COG1024	Enoyl-CoA hydratase
D0819_RS12355	COG5577	PFAM Coat F domain
D0819_RS12360	COG1846	Transcriptional regulator
D0819_RS12365	COG0477	Major facilitator Superfamily
D0819_RS12370	COG1942	4-Oxalocrotonate Tautomerase
D0819_RS12375	COG1028	Short-chain dehydrogenase reductase Sdr
D0819_RS12380	COG0583	DNA-binding transcription factor activity
D0819_RS12390	COG1120	ATPase activity
D0819_RS12405	COG1028	Short-chain dehydrogenase reductase Sdr
D0819_RS12410	COG0783	Belongs to the Dps family
D0819_RS12415	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D0819_RS12420	COG0745	RESPONSE REGULATOR receiver
D0819_RS12425	COG2770	Histidine kinase
D0819_RS12425	COG2205	protein histidine kinase activity
D0819_RS12435	COG1309	transcriptional regulator
D0819_RS12440	COG0114	fumarate hydratase activity
D0819_RS12450	COG0697	spore germination
D0819_RS12455	COG0814	amino acid
D0819_RS12465	COG2197	response regulator
D0819_RS12470	COG4585	Histidine kinase
D0819_RS12475	COG4758	membrane
D0819_RS12480	COG3595	metallopeptidase activity
D0819_RS12485	COG1842	Phage shock protein A
D0819_RS12490	COG4758	membrane
D0819_RS12495	COG2814	Major facilitator Superfamily
D0819_RS12500	COG2096	Adenosyltransferase
D0819_RS12505	COG1120	ATPase activity
D0819_RS12510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0819_RS12515	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D0819_RS12520	COG1028	Short-chain dehydrogenase reductase Sdr
D0819_RS12525	COG3386	PFAM SMP-30 Gluconolaconase
D0819_RS12530	COG2205	protein histidine kinase activity
D0819_RS12535	COG0745	RESPONSE REGULATOR receiver
D0819_RS12545	COG1191	sigma factor activity
D0819_RS12555	COG2140	Oxalate decarboxylase
D0819_RS12565	COG0577	efflux transmembrane transporter activity
D0819_RS12570	COG1136	(ABC) transporter
D0819_RS12575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D0819_RS12580	COG1120	ATPase activity
D0819_RS12585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0819_RS12590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0819_RS12595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D0819_RS12600	COG0531	amino acid
D0819_RS12610	COG1988	membrane-bound metal-dependent
D0819_RS12615	COG1368	sulfuric ester hydrolase activity
D0819_RS12620	COG1910	domain protein
D0819_RS12625	COG0725	ABC transporter, periplasmic molybdate-binding protein
D0819_RS12630	COG4149	molybdate abc transporter
D0819_RS12635	COG0656	L-ascorbic acid biosynthetic process
D0819_RS12645	COG0025	NhaP-type Na H and K H
D0819_RS12650	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D0819_RS12655	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D0819_RS12660	COG3973	AAA domain
D0819_RS12670	COG2860	membrane
D0819_RS12675	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
D0819_RS12680	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D0819_RS12685	COG2217	Heavy metal translocating P-type atpase
D0819_RS12690	COG2217	Heavy metal translocating P-type atpase
D0819_RS12695	COG2608	mercury ion transmembrane transporter activity
D0819_RS12700	COG1937	Protein conserved in bacteria
D0819_RS12705	COG0673	inositol 2-dehydrogenase activity
D0819_RS12710	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D0819_RS12715	COG1289	transmembrane transporter activity
D0819_RS12725	COG2076	Multidrug Resistance protein
D0819_RS12730	COG1309	transcriptional regulator
D0819_RS12735	COG1028	Short-chain dehydrogenase reductase Sdr
D0819_RS12760	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
D0819_RS12765	COG0557	exoribonuclease II activity
D0819_RS12770	COG1647	Serine aminopeptidase, S33
D0819_RS12775	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D0819_RS12780	COG0596	Alpha beta hydrolase
D0819_RS12785	COG1476	TRANSCRIPTIONal
D0819_RS12790	COG1396	sequence-specific DNA binding
D0819_RS12795	COG1396	sequence-specific DNA binding
D0819_RS12800	COG1733	regulation of RNA biosynthetic process
D0819_RS12805	COG0840	transmembrane signaling receptor activity
D0819_RS12810	COG1174	glycine betaine transport
D0819_RS12815	COG1732	Glycine betaine
D0819_RS12820	COG1174	glycine betaine transport
D0819_RS12825	COG1125	glycine betaine transport
D0819_RS12825	COG0517	IMP dehydrogenase activity
D0819_RS12830	COG1510	regulation of RNA biosynthetic process
D0819_RS12835	COG1174	glycine betaine transport
D0819_RS12840	COG1732	Glycine betaine
D0819_RS12845	COG1174	glycine betaine transport
D0819_RS12850	COG1125	glycine betaine transport
D0819_RS12850	COG0517	IMP dehydrogenase activity
D0819_RS12855	COG1510	regulation of RNA biosynthetic process
D0819_RS12860	COG2095	MarC family integral membrane protein
D0819_RS12870	COG3064	Membrane
D0819_RS12875	COG4640	response to antibiotic
D0819_RS12880	COG0456	acetyltransferase
D0819_RS12890	COG0148	phosphopyruvate hydratase activity
D0819_RS12895	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
D0819_RS12900	COG0149	triose-phosphate isomerase activity
D0819_RS12905	COG0126	phosphoglycerate kinase activity
D0819_RS12910	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D0819_RS12915	COG2390	Transcriptional regulator
D0819_RS12920	COG2814	Major facilitator Superfamily
D0819_RS12925	COG1609	Transcriptional regulator
D0819_RS12930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D0819_RS12935	COG0583	DNA-binding transcription factor activity
D0819_RS12940	COG0697	spore germination
D0819_RS12945	COG1113	amino acid transport
D0819_RS12950	COG3858	chitin binding
D0819_RS12955	COG1556	Lactate utilization protein
D0819_RS12960	COG1139	Iron-sulfur cluster binding protein
D0819_RS12965	COG0247	lactate metabolic process
D0819_RS12970	COG2197	response regulator
D0819_RS12975	COG4585	Histidine kinase
D0819_RS12980	COG0842	Transport permease protein
D0819_RS12985	COG1131	(ABC) transporter
D0819_RS12990	COG0596	Alpha beta hydrolase
D0819_RS12995	COG2208	phosphoserine phosphatase activity
D0819_RS13000	COG3867	Arabinogalactan endo-beta-1,4-galactanase
D0819_RS13005	COG1874	Beta-galactosidase
D0819_RS13010	COG3833	ABC-type maltose transport systems, permease component
D0819_RS13015	COG1175	transmembrane transport
D0819_RS13020	COG2182	Extracellular solute-binding protein
D0819_RS13025	COG1609	Transcriptional regulator
D0819_RS13030	COG2186	Transcriptional regulator
D0819_RS13035	COG1620	l-lactate permease
D0819_RS13040	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
D0819_RS13050	COG5039	Polysaccharide pyruvyl transferase
D0819_RS13055	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D0819_RS13060	COG0110	maltose O-acetyltransferase activity
D0819_RS13065	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D0819_RS13070	COG2244	polysaccharide biosynthetic process
D0819_RS13075	COG1216	Glycosyl transferase, family 2
D0819_RS13080	COG5039	Polysaccharide pyruvyl transferase
D0819_RS13085	COG1216	Glycosyl transferase, family 2
D0819_RS13095	COG0438	transferase activity, transferring glycosyl groups
D0819_RS13100	COG1215	transferase activity, transferring glycosyl groups
D0819_RS13105	COG0438	transferase activity, transferring glycosyl groups
D0819_RS13110	COG1086	Polysaccharide biosynthesis protein
D0819_RS13115	COG0489	protein tyrosine kinase activity
D0819_RS13120	COG3944	biosynthesis protein
D0819_RS13125	COG1396	sequence-specific DNA binding
D0819_RS13130	COG2272	Belongs to the type-B carboxylesterase lipase family
D0819_RS13140	COG3479	Phenolic acid decarboxylase
D0819_RS13150	COG1794	racemase activity, acting on amino acids and derivatives
D0819_RS13165	COG1621	beta-fructofuranosidase activity
D0819_RS13170	COG1621	beta-fructofuranosidase activity
D0819_RS13175	COG0531	amino acid
D0819_RS13180	COG1309	transcriptional regulator
D0819_RS13185	COG2076	Multidrug Resistance protein
D0819_RS13190	COG2076	Multidrug Resistance protein
D0819_RS13205	COG0740	serine-type endopeptidase activity
D0819_RS13210	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D0819_RS13215	COG0366	Alpha amylase catalytic
D0819_RS13220	COG1554	hydrolase, family 65, central catalytic
D0819_RS13225	COG5521	maltodextrose utilization protein MalA
D0819_RS13230	COG3833	ABC-type maltose transport systems, permease component
D0819_RS13235	COG1175	transmembrane transport
D0819_RS13240	COG2182	Extracellular solute-binding protein
D0819_RS13245	COG0366	Alpha amylase catalytic
D0819_RS13250	COG1609	Transcriptional regulator
D0819_RS13255	COG1611	Belongs to the LOG family
D0819_RS13260	COG1694	Mazg nucleotide pyrophosphohydrolase
D0819_RS13265	COG0659	secondary active sulfate transmembrane transporter activity
D0819_RS13270	COG0288	reversible hydration of carbon dioxide
D0819_RS13275	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D0819_RS13280	COG0577	efflux transmembrane transporter activity
D0819_RS13285	COG1136	(ABC) transporter
D0819_RS13290	COG5002	protein histidine kinase activity
D0819_RS13295	COG0745	RESPONSE REGULATOR receiver
D0819_RS13305	COG2162	N-hydroxyarylamine O-acetyltransferase activity
D0819_RS13310	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0819_RS13315	COG1481	regulation of sporulation
D0819_RS13320	COG0391	Required for morphogenesis under gluconeogenic growth conditions
D0819_RS13325	COG1660	Displays ATPase and GTPase activities
D0819_RS13330	COG1051	belongs to the nudix hydrolase family
D0819_RS13335	COG0492	ferredoxin-NADP+ reductase activity
D0819_RS13340	COG3883	PFAM NLP P60 protein
D0819_RS13340	COG0791	NLP P60 protein
D0819_RS13345	COG0457	Tetratricopeptide repeat
D0819_RS13350	COG1132	(ABC) transporter
D0819_RS13370	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
D0819_RS13370	COG0140	phosphoribosyl-ATP diphosphatase activity
D0819_RS13375	COG0107	imidazoleglycerol-phosphate synthase activity
D0819_RS13380	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
D0819_RS13385	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
D0819_RS13390	COG0131	Imidazoleglycerol-phosphate dehydratase
D0819_RS13395	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
D0819_RS13400	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
D0819_RS13405	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
D0819_RS13410	COG4990	cell redox homeostasis
D0819_RS13415	COG5297	Belongs to the glycosyl hydrolase family 6
D0819_RS13420	COG0110	maltose O-acetyltransferase activity
D0819_RS13425	COG0546	phosphoglycolate phosphatase activity
D0819_RS13435	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
D0819_RS13440	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
D0819_RS13445	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
D0819_RS13450	COG0363	glucosamine-6-phosphate deaminase activity
D0819_RS13455	COG2188	Transcriptional regulator
D0819_RS13460	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D0819_RS13465	COG1846	Transcriptional regulator
D0819_RS13470	COG2124	cytochrome p450
D0819_RS13480	COG1846	Transcriptional regulator
D0819_RS13485	COG2814	Major facilitator Superfamily
D0819_RS13490	COG1950	PFAM Membrane protein of
D0819_RS13495	COG1983	PspC domain protein
D0819_RS13500	COG3595	metallopeptidase activity
D0819_RS13515	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D0819_RS13520	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D0819_RS13525	COG0556	nucleotide-excision repair
D0819_RS13530	COG4897	Protein conserved in bacteria
D0819_RS13535	COG3848	Pyruvate phosphate dikinase
D0819_RS13535	COG0574	Belongs to the PEP-utilizing enzyme family
D0819_RS13540	COG1309	transcriptional regulator
D0819_RS13545	COG2814	Major facilitator Superfamily
D0819_RS13550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D0819_RS13560	COG0793	Belongs to the peptidase S41A family
D0819_RS13560	COG3409	Peptidoglycan-binding domain 1 protein
D0819_RS13565	COG2177	Part of the ABC transporter FtsEX involved in
D0819_RS13570	COG2884	Cell division ATP-binding protein ftsE
D0819_RS13575	COG2010	Cytochrome c
D0819_RS13580	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D0819_RS13590	COG0653	protein targeting
D0819_RS13595	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
D0819_RS13610	COG1516	flagellar protein fliS
D0819_RS13615	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
D0819_RS13620	COG1334	flagellar protein FlaG
D0819_RS13625	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D0819_RS13630	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
D0819_RS13635	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
D0819_RS13645	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D0819_RS13650	COG1256	bacterial-type flagellum assembly
D0819_RS13650	COG4786	Flagellar basal body rod
D0819_RS13655	COG3418	PFAM FlgN family protein
D0819_RS13660	COG2747	anti-sigma28 factor FlgM
D0819_RS13670	COG1040	competence protein
D0819_RS13680	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
D0819_RS13685	COG1307	EDD domain protein, DegV family
D0819_RS13690	COG2197	response regulator
D0819_RS13695	COG4585	Histidine kinase
D0819_RS13700	COG1739	Uncharacterized protein family UPF0029
D0819_RS13705	COG1316	TRANSCRIPTIONal
D0819_RS13710	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D0819_RS13715	COG0438	transferase activity, transferring glycosyl groups
D0819_RS13720	COG1215	transferase activity, transferring glycosyl groups
D0819_RS13725	COG3206	protein involved in exopolysaccharide biosynthesis
D0819_RS13730	COG3307	-O-antigen
D0819_RS13735	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D0819_RS13740	COG0438	transferase activity, transferring glycosyl groups
D0819_RS13740	COG0297	glycogen (starch) synthase activity
D0819_RS13745	COG2244	polysaccharide biosynthetic process
D0819_RS13760	COG2247	cell wall binding repeat
D0819_RS13760	COG0860	N-Acetylmuramoyl-L-alanine amidase
D0819_RS13765	COG2385	sporulation resulting in formation of a cellular spore
D0819_RS13765	COG2247	cell wall binding repeat
D0819_RS13775	COG1316	TRANSCRIPTIONal
D0819_RS13780	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
D0819_RS13800	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D0819_RS13805	COG1134	teichoic acid transport
D0819_RS13810	COG1682	transport, permease protein
D0819_RS13815	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
D0819_RS13820	COG1442	glycosyl transferase family 8
D0819_RS13820	COG1216	Glycosyl transferase, family 2
D0819_RS13860	COG4193	domain, Protein
D0819_RS13865	COG1482	cell wall glycoprotein biosynthetic process
D0819_RS13870	COG0697	spore germination
D0819_RS13875	COG0814	amino acid
D0819_RS13885	COG2814	Major facilitator Superfamily
D0819_RS13890	COG1316	TRANSCRIPTIONal
D0819_RS13895	COG0561	phosphatase activity
D0819_RS13900	COG0791	NLP P60 protein
D0819_RS13910	COG2843	Capsule synthesis protein
D0819_RS13920	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
D0819_RS13925	COG1609	Transcriptional regulator
D0819_RS13930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D0819_RS13935	COG1869	D-ribose catabolic process
D0819_RS13940	COG1129	ABC transporter
D0819_RS13945	COG1172	Belongs to the binding-protein-dependent transport system permease family
D0819_RS13950	COG1879	ABC-type sugar transport system periplasmic component
D0819_RS13955	COG3103	Sh3 type 3 domain protein
D0819_RS13965	COG2249	NAD(P)H dehydrogenase (quinone) activity
D0819_RS13970	COG3527	Alpha-acetolactate decarboxylase
D0819_RS13975	COG0028	Belongs to the TPP enzyme family
D0819_RS13980	COG0583	DNA-binding transcription factor activity
D0819_RS13985	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D0819_RS14000	COG5337	Spore coat protein CotH
D0819_RS14010	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D0819_RS14020	COG0405	Gamma-glutamyltransferase
D0819_RS14025	COG1522	sequence-specific DNA binding
D0819_RS14030	COG2059	Chromate
D0819_RS14035	COG2059	Chromate
D0819_RS14045	COG0655	NAD(P)H dehydrogenase (quinone) activity
D0819_RS14050	COG0583	DNA-binding transcription factor activity
D0819_RS14055	COG1515	deoxyribonuclease V activity
D0819_RS14070	COG5444	nuclease activity
D0819_RS14090	COG3878	Protein conserved in bacteria
D0819_RS14095	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D0819_RS14100	COG4464	protein tyrosine phosphatase activity
D0819_RS14105	COG0489	protein tyrosine kinase activity
D0819_RS14110	COG3944	biosynthesis protein
D0819_RS14120	COG4715	Zinc finger, swim domain protein
D0819_RS14125	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D0819_RS14130	COG0561	phosphatase activity
D0819_RS14135	COG1349	DNA-binding transcription factor activity
D0819_RS14140	COG0629	single-stranded DNA binding
D0819_RS14155	COG3764	Sortase (surface protein transpeptidase)
D0819_RS14165	COG3279	Response regulator of the LytR AlgR family
D0819_RS14170	COG2972	Histidine kinase
D0819_RS14170	COG0745	RESPONSE REGULATOR receiver
D0819_RS14175	COG1970	mechanosensitive ion channel activity
D0819_RS14180	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D0819_RS14185	COG0457	Tetratricopeptide repeat
D0819_RS14190	COG4786	Flagellar basal body rod
D0819_RS14195	COG4786	Flagellar basal body rod
D0819_RS14200	COG1077	Cell shape determining protein MreB Mrl
D0819_RS14205	COG1609	Transcriptional regulator
D0819_RS14215	COG1846	Transcriptional regulator
D0819_RS14220	COG2814	Major facilitator Superfamily
D0819_RS14225	COG3420	alginic acid biosynthetic process
D0819_RS14230	COG1953	Uracil, thiamine, allantoin
D0819_RS14235	COG0477	Major facilitator Superfamily
D0819_RS14240	COG1335	isochorismatase
D0819_RS14250	COG0004	ammonium transporteR
D0819_RS14255	COG0347	Belongs to the P(II) protein family
D0819_RS14260	COG0671	phosphoesterase, PA-phosphatase related
D0819_RS14270	COG0739	heme binding
D0819_RS14275	COG1247	-acetyltransferase
D0819_RS14295	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D0819_RS14300	COG0789	Transcriptional regulator
D0819_RS14310	COG2910	NAD(P)H-binding
D0819_RS14315	COG1959	2 iron, 2 sulfur cluster binding
D0819_RS14320	COG0804	urea catabolic process
D0819_RS14325	COG0832	Belongs to the urease beta subunit family
D0819_RS14330	COG0831	urea catabolic process
D0819_RS14345	COG3237	CsbD-like
D0819_RS14350	COG1994	Peptidase M50
D0819_RS14355	COG0457	Tetratricopeptide repeat
D0819_RS14360	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
D0819_RS14365	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
D0819_RS14375	COG2304	oxidoreductase activity
D0819_RS14385	COG2304	oxidoreductase activity
D0819_RS14390	COG2385	sporulation resulting in formation of a cellular spore
D0819_RS14395	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D0819_RS14405	COG4836	Membrane
D0819_RS14415	COG0355	proton-transporting ATP synthase activity, rotational mechanism
D0819_RS14420	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
D0819_RS14425	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
D0819_RS14430	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
D0819_RS14435	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D0819_RS14440	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
D0819_RS14450	COG0356	it plays a direct role in the translocation of protons across the membrane
D0819_RS14460	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
D0819_RS14465	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
D0819_RS14470	COG4475	Protein of unknown function (DUF436)
D0819_RS14475	COG0698	ribose 5-phosphate isomerase
D0819_RS14480	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D0819_RS14485	COG1971	Probably functions as a manganese efflux pump
D0819_RS14490	COG0009	L-threonylcarbamoyladenylate synthase
D0819_RS14495	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
D0819_RS14515	COG2890	protein-(glutamine-N5) methyltransferase activity
D0819_RS14520	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
D0819_RS14525	COG0346	lactoylglutathione lyase activity
D0819_RS14530	COG0789	Transcriptional regulator
D0819_RS14535	COG0679	Auxin Efflux Carrier
D0819_RS14540	COG0281	malic enzyme
D0819_RS14545	COG1435	thymidine kinase activity
D0819_RS14555	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
D0819_RS14565	COG1494	fructose-1,6-bisphosphatase
D0819_RS14570	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D0819_RS14575	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
D0819_RS14580	COG0191	fructose-bisphosphate aldolase activity
D0819_RS14585	COG2204	response regulator
D0819_RS14590	COG4821	SIS domain
D0819_RS14595	COG0504	CTP synthase activity
D0819_RS14600	COG3343	RNA polymerase activity
D0819_RS14605	COG1960	acyl-CoA dehydrogenase activity
D0819_RS14610	COG0247	lactate metabolic process
D0819_RS14610	COG2181	nitrate reductase activity
D0819_RS14615	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D0819_RS14620	COG4294	response to UV
D0819_RS14630	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D0819_RS14635	COG1132	(ABC) transporter
D0819_RS14640	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D0819_RS14650	COG2181	nitrate reductase activity
D0819_RS14655	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
D0819_RS14660	COG1140	nitrate reductase beta subunit
D0819_RS14665	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
D0819_RS14670	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D0819_RS14680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D0819_RS14685	COG2223	nitrite transmembrane transporter activity
D0819_RS14690	COG0018	arginyl-trna synthetase
D0819_RS14695	COG4506	Protein conserved in bacteria
D0819_RS14710	COG0535	radical SAM domain protein
D0819_RS14720	COG1131	(ABC) transporter
D0819_RS14725	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D0819_RS14730	COG0612	Peptidase, M16
D0819_RS14735	COG0612	Peptidase, M16
D0819_RS14745	COG3391	amine dehydrogenase activity
D0819_RS14750	COG3391	amine dehydrogenase activity
D0819_RS14760	COG0457	Tetratricopeptide repeat
D0819_RS14780	COG1131	(ABC) transporter
D0819_RS14790	COG0010	Belongs to the arginase family
D0819_RS14795	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
D0819_RS14800	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D0819_RS14815	COG1994	Peptidase M50
D0819_RS14820	COG1942	4-Oxalocrotonate Tautomerase
D0819_RS14825	COG1846	Transcriptional regulator
D0819_RS14830	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D0819_RS14835	COG0477	Major facilitator Superfamily
D0819_RS14840	COG1959	2 iron, 2 sulfur cluster binding
D0819_RS14845	COG3465	dGTPase activity
D0819_RS14850	COG1078	dGTPase activity
D0819_RS14855	COG4844	belongs to the
D0819_RS14865	COG0697	spore germination
D0819_RS14875	COG0095	Lipoate-protein ligase
D0819_RS14880	COG0583	DNA-binding transcription factor activity
D0819_RS14885	COG0280	phosphate acetyltransferase
D0819_RS14890	COG3253	May function as heme-dependent peroxidase
D0819_RS14895	COG1028	Short-chain dehydrogenase reductase Sdr
D0819_RS14900	COG0436	Aminotransferase
D0819_RS14905	COG2814	Major facilitator Superfamily
D0819_RS14910	COG0151	Belongs to the GarS family
D0819_RS14915	COG1028	Short-chain dehydrogenase reductase Sdr
D0819_RS14920	COG1917	Cupin 2, conserved barrel domain protein
D0819_RS14925	COG0077	Prephenate dehydratase
D0819_RS14930	COG2814	Major facilitator Superfamily
D0819_RS14935	COG0833	amino acid
D0819_RS14940	COG4187	Peptidase family M20/M25/M40
D0819_RS14945	COG1012	belongs to the aldehyde dehydrogenase family
D0819_RS14950	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D0819_RS14960	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
D0819_RS14965	COG1091	dTDP-4-dehydrorhamnose reductase activity
D0819_RS14970	COG1088	dTDP-glucose 4,6-dehydratase activity
D0819_RS14975	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
D0819_RS14980	COG3980	spore coat polysaccharide biosynthesis protein
D0819_RS14985	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
D0819_RS14990	COG2089	acid synthase
D0819_RS14995	COG0456	acetyltransferase
D0819_RS15000	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D0819_RS15005	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D0819_RS15010	COG0463	Glycosyl transferase, family 2
D0819_RS15020	COG2363	Small membrane protein
D0819_RS15025	COG2233	PERMEase
D0819_RS15035	COG1012	belongs to the aldehyde dehydrogenase family
D0819_RS15040	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
D0819_RS15045	COG1216	Glycosyl transferase, family 2
D0819_RS15050	COG0351	phosphomethylpyrimidine kinase
D0819_RS15060	COG1621	beta-fructofuranosidase activity
D0819_RS15065	COG1263	PTS System
D0819_RS15065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0819_RS15070	COG2116	formate transmembrane transporter activity
D0819_RS15075	COG3711	transcriptional antiterminator
D0819_RS15085	COG1404	Belongs to the peptidase S8 family
D0819_RS15090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D0819_RS15095	COG0778	Nitroreductase
D0819_RS15100	COG0772	Belongs to the SEDS family
D0819_RS15110	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
D0819_RS15115	COG1845	cytochrome c oxidase, subunit III
D0819_RS15120	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D0819_RS15125	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D0819_RS15130	COG2261	transglycosylase associated protein
D0819_RS15135	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
D0819_RS15140	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
D0819_RS15145	COG2246	polysaccharide biosynthetic process
D0819_RS15150	COG1309	transcriptional regulator
D0819_RS15160	COG3162	membrane
D0819_RS15165	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D0819_RS15170	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
D0819_RS15175	COG2837	iron assimilation
D0819_RS15180	COG2822	iron ion transport
D0819_RS15185	COG0672	)-iron permease
D0819_RS15190	COG0352	thiamine-phosphate diphosphorylase activity
D0819_RS15195	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
D0819_RS15200	COG0583	DNA-binding transcription factor activity
D0819_RS15205	COG1380	Effector of murein hydrolase LrgA
D0819_RS15210	COG1346	cytolysis
D0819_RS15215	COG2814	Major facilitator Superfamily
D0819_RS15220	COG4895	conserved protein (DUF2196)
D0819_RS15225	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
D0819_RS15230	COG0346	lactoylglutathione lyase activity
D0819_RS15240	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D0819_RS15245	COG1404	Belongs to the peptidase S8 family
D0819_RS15250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0819_RS15250	COG1263	PTS System
D0819_RS15255	COG3711	transcriptional antiterminator
D0819_RS15260	COG1442	glycosyl transferase family 8
D0819_RS15265	COG5522	Integral membrane protein (intg_mem_TP0381)
D0819_RS15270	COG1846	Transcriptional regulator
D0819_RS15275	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D0819_RS15280	COG2234	aminopeptidase activity
D0819_RS15285	COG2357	RelA SpoT domain protein
D0819_RS15290	COG1575	Belongs to the MenA family. Type 1 subfamily
D0819_RS15305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0819_RS15310	COG1696	Membrane protein involved in D-alanine export
D0819_RS15315	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D0819_RS15320	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
D0819_RS15325	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
D0819_RS15330	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D0819_RS15335	COG1486	melibiose metabolic process
D0819_RS15340	COG1447	Phosphotransferase system cellobiose-specific component IIA
D0819_RS15345	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D0819_RS15350	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D0819_RS15355	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0819_RS15355	COG3711	transcriptional antiterminator
D0819_RS15365	COG2094	Belongs to the DNA glycosylase MPG family
D0819_RS15370	COG0753	catalase activity
D0819_RS15375	COG2814	Major facilitator Superfamily
D0819_RS15380	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D0819_RS15385	COG1131	(ABC) transporter
D0819_RS15405	COG1595	DNA-templated transcription, initiation
D0819_RS15410	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D0819_RS15415	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
D0819_RS15420	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
D0819_RS15425	COG4988	ABC transporter
D0819_RS15430	COG1294	oxidase, subunit
D0819_RS15435	COG1271	oxidase subunit
D0819_RS15440	COG3493	citrate carrier protein
D0819_RS15445	COG0501	Belongs to the peptidase M48B family
D0819_RS15455	COG0726	polysaccharide deacetylase
D0819_RS15460	COG3842	ATPase activity
D0819_RS15465	COG2508	Transcriptional regulator
D0819_RS15470	COG1012	belongs to the aldehyde dehydrogenase family
D0819_RS15475	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D0819_RS15485	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D0819_RS15490	COG1881	PFAM PEBP family protein
D0819_RS15495	COG0583	DNA-binding transcription factor activity
D0819_RS15505	COG4585	Histidine kinase
D0819_RS15510	COG2197	response regulator
D0819_RS15515	COG2195	Cleaves the N-terminal amino acid of tripeptides
D0819_RS15525	COG4894	glucomannan catabolic process
D0819_RS15530	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D0819_RS15535	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D0819_RS15540	COG1028	Short-chain dehydrogenase reductase Sdr
D0819_RS15545	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D0819_RS15550	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D0819_RS15555	COG2610	gluconate transmembrane transporter activity
D0819_RS15560	COG0500	methyltransferase
D0819_RS15565	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D0819_RS15580	COG0753	catalase activity
D0819_RS15580	COG0693	protein deglycase activity
D0819_RS15585	COG2851	Citrate transporter
D0819_RS15590	COG2273	Hydrolase Family 16
D0819_RS15595	COG3711	transcriptional antiterminator
D0819_RS15605	COG2270	Major facilitator Superfamily
D0819_RS15610	COG0513	Belongs to the DEAD box helicase family
D0819_RS15615	COG3401	FG-GAP repeat protein
D0819_RS15615	COG2755	lipolytic protein G-D-S-L family
D0819_RS15675	COG0697	spore germination
D0819_RS15690	COG0589	response to stress
D0819_RS15695	COG2723	6-phospho-beta-galactosidase activity
D0819_RS15700	COG2190	(PTS) system
D0819_RS15700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0819_RS15700	COG1263	PTS System
D0819_RS15715	COG5444	nuclease activity
D0819_RS15750	COG3507	Belongs to the glycosyl hydrolase 43 family
D0819_RS15765	COG2986	histidine ammonia-lyase
D0819_RS15770	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
D0819_RS15775	COG1228	amidohydrolase
D0819_RS15780	COG0010	Belongs to the arginase family
D0819_RS15785	COG0833	amino acid
D0819_RS15790	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
D0819_RS15795	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D0819_RS15800	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
D0819_RS15805	COG2390	Transcriptional regulator
D0819_RS15815	COG3192	ethanolamine utilization protein
D0819_RS15820	COG2079	MmgE PrpD family protein
D0819_RS15825	COG1473	amidohydrolase
D0819_RS15830	COG1126	abc transporter atp-binding protein
D0819_RS15835	COG0765	amino acid transport
D0819_RS15840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0819_RS15845	COG0456	acetyltransferase
D0819_RS15850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D0819_RS15860	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
D0819_RS15865	COG0561	phosphatase activity
D0819_RS15895	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D0819_RS15900	COG5294	Protein conserved in bacteria
D0819_RS15905	COG0577	efflux transmembrane transporter activity
D0819_RS15910	COG1136	(ABC) transporter
D0819_RS15915	COG2205	protein histidine kinase activity
D0819_RS15920	COG0745	RESPONSE REGULATOR receiver
D0819_RS15925	COG0191	fructose-bisphosphate aldolase activity
D0819_RS15930	COG1082	Xylose isomerase domain protein TIM barrel
D0819_RS15935	COG1082	Xylose isomerase domain protein TIM barrel
D0819_RS15940	COG0673	inositol 2-dehydrogenase activity
D0819_RS15945	COG2814	Major facilitator Superfamily
D0819_RS15950	COG1082	Xylose isomerase domain protein TIM barrel
D0819_RS15955	COG3962	Belongs to the TPP enzyme family
D0819_RS15960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D0819_RS15970	COG1012	belongs to the aldehyde dehydrogenase family
D0819_RS15975	COG1349	DNA-binding transcription factor activity
D0819_RS15980	COG0667	Aldo Keto reductase
D0819_RS16010	COG2814	Major facilitator Superfamily
D0819_RS16015	COG0326	Molecular chaperone. Has ATPase activity
D0819_RS16025	COG1028	Short-chain dehydrogenase reductase Sdr
D0819_RS16030	COG1309	transcriptional regulator
D0819_RS16035	COG1012	belongs to the aldehyde dehydrogenase family
D0819_RS16045	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D0819_RS16055	COG1714	RDD family
D0819_RS16060	COG2311	Membrane
D0819_RS16065	COG1917	Cupin 2, conserved barrel domain protein
D0819_RS16070	COG1309	transcriptional regulator
D0819_RS16075	COG1028	Short-chain dehydrogenase reductase Sdr
D0819_RS16080	COG1846	Transcriptional regulator
D0819_RS16085	COG1380	Effector of murein hydrolase LrgA
D0819_RS16090	COG1346	cytolysis
D0819_RS16095	COG5039	Polysaccharide pyruvyl transferase
D0819_RS16100	COG1929	Belongs to the glycerate kinase type-1 family
D0819_RS16105	COG1802	Transcriptional regulator
D0819_RS16110	COG1070	Carbohydrate kinase
D0819_RS16115	COG2610	gluconate transmembrane transporter activity
D0819_RS16120	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D0819_RS16125	COG0450	alkyl hydroperoxide reductase
D0819_RS16130	COG3634	alkyl hydroperoxide reductase activity
D0819_RS16140	COG2723	6-phospho-beta-galactosidase activity
D0819_RS16155	COG2188	Transcriptional regulator
D0819_RS16170	COG1131	(ABC) transporter
D0819_RS16175	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
D0819_RS16185	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
D0819_RS16200	COG1063	alcohol dehydrogenase
D0819_RS16225	COG0456	acetyltransferase
D0819_RS16230	COG0457	Tetratricopeptide repeat
D0819_RS16240	COG0010	Belongs to the arginase family
D0819_RS16245	COG0833	amino acid
D0819_RS16250	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D0819_RS16255	COG3829	transcription factor binding
D0819_RS16265	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D0819_RS16270	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
D0819_RS16275	COG4853	Protein conserved in bacteria
D0819_RS16280	COG4863	YycH protein
D0819_RS16285	COG5002	protein histidine kinase activity
D0819_RS16290	COG0745	RESPONSE REGULATOR receiver
D0819_RS16320	COG0346	lactoylglutathione lyase activity
D0819_RS16325	COG0305	Participates in initiation and elongation during chromosome replication
D0819_RS16340	COG3093	addiction module antidote protein HigA
D0819_RS16345	COG2807	transmembrane transport
D0819_RS16350	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
D0819_RS16355	COG0359	binds to the 23S rRNA
D0819_RS16360	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
D0819_RS16365	COG4241	membrane
D0819_RS16375	COG5577	PFAM Coat F domain
D0819_RS16380	COG1733	regulation of RNA biosynthetic process
D0819_RS16385	COG1227	inorganic diphosphatase activity
D0819_RS16400	COG2271	Major facilitator Superfamily
D0819_RS16405	COG4978	Transcriptional regulator
D0819_RS16405	COG0789	Transcriptional regulator
D0819_RS16415	COG4319	ketosteroid isomerase
D0819_RS16420	COG1357	PFAM Pentapeptide repeats (8 copies)
D0819_RS16425	COG2814	Major facilitator Superfamily
D0819_RS16430	COG0583	DNA-binding transcription factor activity
D0819_RS16435	COG2153	protein acetylation
D0819_RS16445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D0819_RS16450	COG1846	Transcriptional regulator
D0819_RS16455	COG2153	protein acetylation
D0819_RS16460	COG2364	Membrane
D0819_RS16465	COG0456	acetyltransferase
D0819_RS16470	COG2315	Protein conserved in bacteria
D0819_RS16475	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D0819_RS16505	COG1331	Highly conserved protein containing a thioredoxin domain
D0819_RS16510	COG1266	CAAX protease self-immunity
D0819_RS16515	COG2814	Major facilitator Superfamily
D0819_RS16515	COG0477	Major facilitator Superfamily
D0819_RS16520	COG0110	maltose O-acetyltransferase activity
D0819_RS16525	COG0346	lactoylglutathione lyase activity
D0819_RS16530	COG1609	Transcriptional regulator
D0819_RS16535	COG0708	Exodeoxyribonuclease III
D0819_RS16540	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
D0819_RS16545	COG0629	single-stranded DNA binding
D0819_RS16550	COG0360	Binds together with S18 to 16S ribosomal RNA
D0819_RS16555	COG0012	GTP binding
D0819_RS16560	COG0243	molybdopterin cofactor binding
D0819_RS16565	COG4481	Protein conserved in bacteria
D0819_RS16570	COG3949	Membrane
D0819_RS16580	COG1475	DNA binding
D0819_RS16585	COG1192	Involved in chromosome partitioning
D0819_RS16595	COG1475	DNA binding
D0819_RS16600	COG0357	Ribosomal RNA small subunit methyltransferase G
D0819_RS16605	COG0445	tRNA wobble uridine modification
D0819_RS16610	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
D0819_RS16615	COG1847	R3H domain protein
D0819_RS16620	COG0706	membrane insertase activity
D0819_RS16625	COG0594	ribonuclease P activity
D0819_RS16635	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
D0819_RS16640	COG0592	DNA-directed DNA polymerase activity
D0819_RS16645	COG2501	S4 domain
D0819_RS16650	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
D0819_RS16660	COG0187	DNA topoisomerase II activity
D0819_RS16665	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D0819_RS16690	COG0517	IMP dehydrogenase activity
D0819_RS16690	COG0516	GMP reductase activity
D0819_RS16695	COG1686	Belongs to the peptidase S11 family
D0819_RS16700	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
D0819_RS16705	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
D0819_RS16710	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
D0819_RS16720	COG1428	Deoxynucleoside kinase
D0819_RS16725	COG1428	Deoxynucleoside kinase
D0819_RS16730	COG3858	chitin binding
D0819_RS16730	COG1388	LysM domain
D0819_RS16735	COG1335	isochorismatase
D0819_RS16740	COG0590	tRNA wobble adenosine to inosine editing
D0819_RS16750	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
D0819_RS16755	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
D0819_RS16760	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
D0819_RS16795	COG0517	IMP dehydrogenase activity
D0819_RS16795	COG0516	GMP reductase activity
D0819_RS16800	COG1686	Belongs to the peptidase S11 family
D0819_RS16805	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
D0819_RS16810	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
D0819_RS16815	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
D0819_RS16825	COG1428	Deoxynucleoside kinase
D0819_RS16830	COG1428	Deoxynucleoside kinase
D0819_RS16835	COG1388	LysM domain
D0819_RS16835	COG3858	chitin binding
D0819_RS16840	COG1335	isochorismatase
D0819_RS16845	COG0590	tRNA wobble adenosine to inosine editing
D0819_RS16855	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
D0819_RS16860	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
D0819_RS16865	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
D0819_RS16960	COG0517	IMP dehydrogenase activity
D0819_RS16960	COG0516	GMP reductase activity
D0819_RS16965	COG1686	Belongs to the peptidase S11 family
D0819_RS16970	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
D0819_RS16975	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
D0819_RS16980	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
D0819_RS16990	COG1428	Deoxynucleoside kinase
D0819_RS16995	COG1428	Deoxynucleoside kinase
D0819_RS17000	COG3858	chitin binding
D0819_RS17000	COG1388	LysM domain
D0819_RS17005	COG1335	isochorismatase
D0819_RS17010	COG0590	tRNA wobble adenosine to inosine editing
D0819_RS17020	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
D0819_RS17025	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
D0819_RS17030	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
D0819_RS17065	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
D0819_RS17070	COG3853	Toxic anion resistance protein (TelA)
D0819_RS17075	COG1982	Orn Lys Arg decarboxylase major
D0819_RS17080	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
D0819_RS17085	COG3870	Protein conserved in bacteria
D0819_RS17090	COG1728	Protein conserved in bacteria
D0819_RS17095	COG0470	DNA polymerase III
D0819_RS17100	COG1774	PSP1 C-terminal conserved region
D0819_RS17105	COG4467	Involved in initiation control of chromosome replication
D0819_RS17110	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
D0819_RS17115	COG2827	Endonuclease containing a URI domain
D0819_RS17120	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
D0819_RS17125	COG2002	toxin-antitoxin pair type II binding
D0819_RS17130	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D0819_RS17130	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D0819_RS17135	COG0084	hydrolase, TatD family'
D0819_RS17140	COG3584	3D domain protein
D0819_RS17140	COG3583	domain protein
D0819_RS17145	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
D0819_RS17150	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
D0819_RS17160	COG4466	Protein conserved in bacteria
D0819_RS17170	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
D0819_RS17175	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D0819_RS17180	COG0251	oxidation-reduction process
D0819_RS17185	COG2088	sporulation resulting in formation of a cellular spore
D0819_RS17190	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
D0819_RS17195	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
D0819_RS17200	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
D0819_RS17205	COG0193	aminoacyl-tRNA hydrolase activity
D0819_RS17215	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D0819_RS17220	COG2002	toxin-antitoxin pair type II binding
D0819_RS17225	COG2244	polysaccharide biosynthetic process
D0819_RS17230	COG3956	TIGRFAM MazG family protein
D0819_RS17235	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
D0819_RS17250	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
D0819_RS17255	COG1098	S1 RNA binding domain
D0819_RS17270	COG2208	phosphoserine phosphatase activity
D0819_RS17275	COG2304	oxidoreductase activity
D0819_RS17280	COG0515	serine threonine protein kinase
D0819_RS17285	COG0037	tRNA processing
D0819_RS17290	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
D0819_RS17295	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D0819_RS17300	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
D0819_RS17305	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
D0819_RS17310	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D0819_RS17315	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D0819_RS17320	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D0819_RS17325	COG0512	Glutamine amidotransferase of anthranilate synthase
D0819_RS17330	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D0819_RS17335	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
D0819_RS17340	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
D0819_RS17345	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D0819_RS17350	COG1396	sequence-specific DNA binding
D0819_RS17355	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D0819_RS17360	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
D0819_RS17440	COG4463	regulation of RNA biosynthetic process
D0819_RS17445	COG3880	PFAM UvrB UvrC protein
D0819_RS17450	COG3869	Catalyzes the specific phosphorylation of arginine residues in
D0819_RS17455	COG0542	response to heat
D0819_RS17460	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
D0819_RS17465	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
D0819_RS17470	COG4956	integral membrane protein (PIN domain superfamily)
D0819_RS17475	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
D0819_RS17480	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
D0819_RS17485	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D0819_RS17490	COG1045	serine acetyltransferase
D0819_RS17495	COG0215	cysteine-tRNA ligase activity
D0819_RS17500	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
D0819_RS17505	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D0819_RS17510	COG3688	RNA-binding protein containing a PIN domain
D0819_RS17515	COG1595	DNA-templated transcription, initiation
D0819_RS17525	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D0819_RS17530	COG0250	Participates in transcription elongation, termination and antitermination
D0819_RS17540	COG0081	regulation of translation
D0819_RS17545	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
D0819_RS17555	COG2813	Specifically methylates the guanine in position
D0819_RS17560	COG0085	RNA polymerase activity
D0819_RS17565	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
D0819_RS17570	COG1358	cellular component organization or biogenesis
D0819_RS17575	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
D0819_RS17580	COG0049	tRNA binding
D0819_RS17585	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
D0819_RS17590	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
D0819_RS17595	COG0596	Alpha beta hydrolase
D0819_RS17605	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
D0819_RS17610	COG0088	Forms part of the polypeptide exit tunnel
D0819_RS17620	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
D0819_RS17635	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
D0819_RS17640	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
D0819_RS17650	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
D0819_RS17655	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
D0819_RS17665	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
D0819_RS17675	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
D0819_RS17680	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
D0819_RS17685	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
D0819_RS17690	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
D0819_RS17700	COG0200	Binds to the 23S rRNA
D0819_RS17705	COG0201	protein transport
D0819_RS17710	COG0563	adenylate kinase activity
D0819_RS17715	COG0024	Methionine aminopeptidase
D0819_RS17720	COG2163	COG2163 Ribosomal protein L14E L6E L27E
D0819_RS17730	COG0257	Belongs to the bacterial ribosomal protein bL36 family
D0819_RS17735	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
D0819_RS17740	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
D0819_RS17745	COG0202	RNA polymerase activity
D0819_RS17750	COG0203	ribosomal protein L17
D0819_RS17755	COG1122	ATPase activity
D0819_RS17760	COG1122	ATPase activity
D0819_RS17765	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D0819_RS17770	COG0101	tRNA pseudouridine synthase activity
D0819_RS17775	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
D0819_RS17780	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
D0819_RS17785	COG2226	methyltransferase
D0819_RS17795	COG0860	N-Acetylmuramoyl-L-alanine amidase
D0819_RS17800	COG0489	protein tyrosine kinase activity
D0819_RS17810	COG2194	sulfuric ester hydrolase activity
D0819_RS17815	COG0726	polysaccharide deacetylase
D0819_RS17880	COG0659	secondary active sulfate transmembrane transporter activity
D0819_RS17885	COG0385	Bile acid
D0819_RS17895	COG2746	aminoglycoside 3-N-acetyltransferase activity
D0819_RS17900	COG0747	negative chemotaxis
D0819_RS17910	COG1136	(ABC) transporter
D0819_RS17915	COG2814	Major facilitator Superfamily
D0819_RS17925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0819_RS17930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0819_RS17935	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D0819_RS17940	COG2207	Transcriptional regulator
D0819_RS17940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D0819_RS17945	COG3876	Protein conserved in bacteria
D0819_RS17950	COG1472	Belongs to the glycosyl hydrolase 3 family
D0819_RS17955	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D0819_RS17960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0819_RS17960	COG1263	PTS System
D0819_RS17965	COG1737	Transcriptional regulator
D0819_RS17970	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
D0819_RS17975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D0819_RS17980	COG1683	Conserved Protein
D0819_RS18010	COG1595	DNA-templated transcription, initiation
D0819_RS18015	COG5662	AntiSigma factor
D0819_RS18020	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
D0819_RS18025	COG4856	YbbR-like protein
D0819_RS18030	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D0819_RS18035	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D0819_RS18040	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D0819_RS18045	COG3002	Belongs to the UPF0753 family
D0819_RS18050	COG0288	reversible hydration of carbon dioxide
D0819_RS18060	COG5609	conserved protein (DUF2294)
D0819_RS18065	COG0640	Transcriptional regulator
D0819_RS18070	COG2814	Major facilitator Superfamily
D0819_RS18085	COG0515	serine threonine protein kinase
D0819_RS18100	COG1113	amino acid transport
D0819_RS18115	COG2602	Beta-lactamase
D0819_RS18120	COG2124	cytochrome p450
D0819_RS18130	COG0531	amino acid
D0819_RS18135	COG0584	glycerophosphoryl diester phosphodiesterase
D0819_RS18140	COG2271	Major facilitator Superfamily
D0819_RS18150	COG1846	Transcriptional regulator
D0819_RS18150	COG0456	acetyltransferase
D0819_RS18155	COG2271	Major facilitator Superfamily
D0819_RS18170	COG3409	Peptidoglycan-binding domain 1 protein
D0819_RS18175	COG0697	spore germination
D0819_RS18180	COG1917	Cupin 2, conserved barrel domain protein
D0819_RS18180	COG2207	Transcriptional regulator
D0819_RS18185	COG1397	ADP-ribosylglycohydrolase
D0819_RS18190	COG5444	nuclease activity
D0819_RS18195	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
D0819_RS18200	COG3591	Belongs to the peptidase S1B family
D0819_RS18210	COG0596	Alpha beta hydrolase
D0819_RS18215	COG1183	phosphatidylcholine synthase activity
D0819_RS18220	COG0586	Pfam SNARE associated Golgi protein
D0819_RS18225	COG0688	phosphatidylethanolamine metabolic process
D0819_RS18235	COG2312	Erythromycin esterase
D0819_RS18240	COG1054	Belongs to the UPF0176 family
D0819_RS18245	COG1301	dicarboxylic acid transport
D0819_RS18250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0819_RS18250	COG2190	(PTS) system
D0819_RS18250	COG1263	PTS System
D0819_RS18255	COG0363	glucosamine-6-phosphate deaminase activity
D0819_RS18260	COG2188	Transcriptional regulator
D0819_RS18270	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D0819_RS18275	COG0833	amino acid
D0819_RS18280	COG2040	homocysteine
D0819_RS18290	COG1115	amino acid carrier protein
D0819_RS18295	COG2066	Belongs to the glutaminase family
D0819_RS18300	COG4191	Histidine kinase
D0819_RS18305	COG0784	Response regulator, receiver
D0819_RS18310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D0819_RS18315	COG1012	belongs to the aldehyde dehydrogenase family
D0819_RS18320	COG2271	Major facilitator Superfamily
D0819_RS18325	COG4948	Mandelate Racemase Muconate Lactonizing
D0819_RS18330	COG2186	Transcriptional regulator
D0819_RS18335	COG2721	sulfolactate sulfo-lyase activity
D0819_RS18340	COG3173	Aminoglycoside phosphotransferase
D0819_RS18350	COG0697	spore germination
D0819_RS18355	COG0745	RESPONSE REGULATOR receiver
D0819_RS18360	COG2205	protein histidine kinase activity
D0819_RS18365	COG1131	(ABC) transporter
D0819_RS18385	COG3773	Cell wall hydrolase
D0819_RS18390	COG2304	oxidoreductase activity
D0819_RS18400	COG3540	Alkaline phosphatase
D0819_RS18405	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D0819_RS18410	COG0805	protein transport
D0819_RS18415	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
D0819_RS18420	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D0819_RS18425	COG0477	Major facilitator Superfamily
D0819_RS18430	COG1309	transcriptional regulator
D0819_RS18435	COG0252	asparaginase activity
D0819_RS18440	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
D0819_RS18445	COG1714	RDD family
D0819_RS18450	COG3012	SEC-C Motif Domain Protein
D0819_RS18450	COG1405	negative regulation of cell septum assembly
D0819_RS18455	COG3290	protein histidine kinase activity
D0819_RS18460	COG3279	Response regulator of the LytR AlgR family
D0819_RS18465	COG4555	ABC transporter
D0819_RS18470	COG1668	transmembrane transport
D0819_RS18475	COG0667	Aldo Keto reductase
D0819_RS18490	COG1595	DNA-templated transcription, initiation
D0819_RS18495	COG1595	DNA-templated transcription, initiation
D0819_RS18500	COG1876	peptidase activity
D0819_RS18505	COG0457	Tetratricopeptide repeat
D0819_RS18510	COG1028	Short-chain dehydrogenase reductase Sdr
D0819_RS18520	COG0803	Belongs to the bacterial solute-binding protein 9 family
D0819_RS18525	COG1121	(ABC) transporter
D0819_RS18530	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D0819_RS18535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D0819_RS18540	COG2310	stress, protein
D0819_RS18545	COG2310	stress, protein
D0819_RS18550	COG2310	stress, protein
D0819_RS18555	COG0861	Integral membrane protein TerC family
D0819_RS18565	COG3853	Toxic anion resistance protein (TelA)
D0819_RS18570	COG0477	Major facilitator Superfamily
D0819_RS18575	COG2814	Major facilitator Superfamily
D0819_RS18580	COG0640	Transcriptional regulator
D0819_RS18585	COG0517	IMP dehydrogenase activity
D0819_RS18585	COG4175	Glycine betaine
D0819_RS18590	COG4176	ABC-type proline glycine betaine transport system permease component
D0819_RS18595	COG2113	Glycine betaine
D0819_RS18600	COG1473	amidohydrolase
D0819_RS18605	COG1288	antiporter activity
D0819_RS18615	COG0366	Alpha amylase catalytic
D0819_RS18620	COG0039	L-malate dehydrogenase activity
D0819_RS18625	COG1620	l-lactate permease
D0819_RS18630	COG2814	Major facilitator Superfamily
D0819_RS18635	COG1846	Transcriptional regulator
D0819_RS18640	COG1280	lysine exporter protein (LysE YggA)
D0819_RS18645	COG3403	YqcI/YcgG family
D0819_RS18650	COG1113	amino acid transport
D0819_RS18655	COG3665	Urea carboxylase-associated protein
D0819_RS18660	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
D0819_RS18665	COG1660	Displays ATPase and GTPase activities
D0819_RS18670	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
D0819_RS18675	COG2226	methyltransferase
D0819_RS18680	COG0583	DNA-binding transcription factor activity
D0819_RS18685	COG3458	cephalosporin-C deacetylase activity
D0819_RS18690	COG3541	Predicted nucleotidyltransferase
D0819_RS18695	COG0506	proline dehydrogenase activity
D0819_RS18700	COG1012	belongs to the aldehyde dehydrogenase family
D0819_RS18705	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D0819_RS18710	COG2508	Transcriptional regulator
D0819_RS18715	COG3689	TIGRFAM TIGR03943 family protein
D0819_RS18720	COG0701	Predicted permease
D0819_RS18725	COG2267	carboxylic ester hydrolase activity
D0819_RS18730	COG0492	ferredoxin-NADP+ reductase activity
D0819_RS18735	COG1587	Uroporphyrinogen-III synthase
D0819_RS18735	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D0819_RS18740	COG2146	nitrite reductase [NAD(P)H] activity
D0819_RS18745	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D0819_RS18750	COG0243	molybdopterin cofactor binding
D0819_RS18755	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D0819_RS18760	COG2223	nitrite transmembrane transporter activity
D0819_RS18765	COG1469	GTP cyclohydrolase I activity
D0819_RS18770	COG1376	ErfK ybiS ycfS ynhG family protein
D0819_RS18785	COG0523	cobalamin synthesis protein
D0819_RS18790	COG0765	amino acid transport
D0819_RS18795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0819_RS18815	COG1846	Transcriptional regulator
D0819_RS18825	COG3842	ATPase activity
D0819_RS18830	COG2723	6-phospho-beta-galactosidase activity
D0819_RS18840	COG3209	COG3209 Rhs family protein
D0819_RS18845	COG3290	protein histidine kinase activity
D0819_RS18845	COG0840	transmembrane signaling receptor activity
D0819_RS18850	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
D0819_RS18855	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
D0819_RS18860	COG1733	regulation of RNA biosynthetic process
D0819_RS18865	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0819_RS18870	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0819_RS18875	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0819_RS18880	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
D0819_RS18885	COG2814	Major facilitator Superfamily
D0819_RS18895	COG0697	spore germination
D0819_RS18900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D0819_RS18910	COG2364	Membrane
D0819_RS18915	COG1126	abc transporter atp-binding protein
D0819_RS18920	COG0765	amino acid transport
D0819_RS18925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0819_RS18930	COG0583	DNA-binding transcription factor activity
D0819_RS18935	COG0163	prenyltransferase activity
D0819_RS18940	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
D0819_RS18955	COG0596	Alpha beta hydrolase
D0819_RS18960	COG3104	oligopeptide transport
D0819_RS18965	COG5434	Belongs to the glycosyl hydrolase 28 family
D0819_RS18975	COG0697	spore germination
D0819_RS18985	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D0819_RS18990	COG1136	(ABC) transporter
D0819_RS18995	COG0577	efflux transmembrane transporter activity
D0819_RS19000	COG0745	RESPONSE REGULATOR receiver
D0819_RS19005	COG5002	protein histidine kinase activity
D0819_RS19005	COG3850	Histidine kinase
D0819_RS19010	COG0457	Tetratricopeptide repeat
D0819_RS19030	COG0527	aspartate kinase activity
D0819_RS19035	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0819_RS19040	COG4605	iron ion homeostasis
D0819_RS19045	COG4604	ABC transporter, ATP-binding protein
D0819_RS19050	COG4607	ABC-type enterochelin transport system periplasmic component
D0819_RS19055	COG2814	Major facilitator Superfamily
D0819_RS19060	COG1309	transcriptional regulator
D0819_RS19065	COG0778	Nitroreductase
D0819_RS19070	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
D0819_RS19075	COG0640	Transcriptional regulator
D0819_RS19080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D0819_RS19085	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D0819_RS19090	COG1012	belongs to the aldehyde dehydrogenase family
D0819_RS19095	COG4975	Glucose uptake
D0819_RS19100	COG1028	Short-chain dehydrogenase reductase Sdr
D0819_RS19105	COG4549	nuclear export factor GLE1
D0819_RS19110	COG2372	response to copper ion
D0819_RS19110	COG1276	copper resistance
D0819_RS19115	COG1349	DNA-binding transcription factor activity
D0819_RS19125	COG2213	PTS system mannitol-specific
D0819_RS19130	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0819_RS19135	COG0246	Mannitol dehydrogenase
D0819_RS19140	COG0473	3-isopropylmalate dehydrogenase activity
D0819_RS19145	COG0681	Belongs to the peptidase S26 family
D0819_RS19150	COG0412	Dienelactone hydrolase
D0819_RS19155	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D0819_RS19165	COG0561	phosphatase activity
D0819_RS19170	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
D0819_RS19175	COG1914	H( )-stimulated, divalent metal cation uptake system
D0819_RS19180	COG4336	lyase activity
D0819_RS19185	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
D0819_RS19190	COG1984	allophanate hydrolase subunit 2
D0819_RS19195	COG1414	Transcriptional regulator
D0819_RS19200	COG2755	lipolytic protein G-D-S-L family
D0819_RS19210	COG2329	Antibiotic biosynthesis monooxygenase
D0819_RS19215	COG0768	penicillin binding
D0819_RS19220	COG4989	oxidoreductase activity
D0819_RS19225	COG3711	transcriptional antiterminator
D0819_RS19230	COG0318	PFAM AMP-dependent synthetase and ligase
D0819_RS19235	COG2226	methyltransferase
D0819_RS19240	COG1028	Short-chain dehydrogenase reductase Sdr
D0819_RS19245	COG1917	Cupin 2, conserved barrel domain protein
D0819_RS19250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D0819_RS19255	COG3871	stress protein (general stress protein 26)
D0819_RS19265	COG2814	Major facilitator Superfamily
D0819_RS19270	COG1522	sequence-specific DNA binding
D0819_RS19275	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D0819_RS19275	COG0551	DNA topoisomerase type I activity
D0819_RS19280	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
D0819_RS19285	COG3706	GGDEF domain
D0819_RS19290	COG5298	Protein conserved in bacteria
D0819_RS19295	COG1215	transferase activity, transferring glycosyl groups
D0819_RS19305	COG0531	amino acid
D0819_RS19310	COG0494	nUDIX hydrolase
D0819_RS19315	COG0028	Belongs to the TPP enzyme family
D0819_RS19330	COG1914	H( )-stimulated, divalent metal cation uptake system
D0819_RS19335	COG2261	transglycosylase associated protein
D0819_RS19340	COG4876	unkown
D0819_RS19345	COG2217	Heavy metal translocating P-type atpase
D0819_RS19350	COG3729	General stress protein
D0819_RS19355	COG0662	Cupin 2, conserved barrel domain protein
D0819_RS19360	COG2329	Antibiotic biosynthesis monooxygenase
D0819_RS19365	COG3546	catalase activity
D0819_RS19370	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D0819_RS19375	COG3290	protein histidine kinase activity
D0819_RS19380	COG4565	transcriptional regulatory protein
D0819_RS19385	COG1301	dicarboxylic acid transport
D0819_RS19390	COG0628	permease
D0819_RS19395	COG1131	(ABC) transporter
D0819_RS19400	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D0819_RS19410	COG1960	acyl-CoA dehydrogenase activity
D0819_RS19425	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D0819_RS19430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D0819_RS19435	COG1181	Belongs to the D-alanine--D-alanine ligase family
D0819_RS19440	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D0819_RS19445	COG0513	Belongs to the DEAD box helicase family
D0819_RS19450	COG3402	PFAM membrane-flanked domain
D0819_RS19455	COG3428	Bacterial PH domain
D0819_RS19460	COG0705	Rhomboid family
D0819_RS19465	COG0736	holo-[acyl-carrier-protein] synthase activity
D0819_RS19470	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
D0819_RS19475	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D0819_RS19480	COG0864	Transcriptional regulator
D0819_RS19485	COG2337	Toxic component of a toxin-antitoxin (TA) module
D0819_RS19490	COG1366	Belongs to the anti-sigma-factor antagonist family
D0819_RS19495	COG1366	Belongs to the anti-sigma-factor antagonist family
D0819_RS19500	COG2172	sigma factor antagonist activity
D0819_RS19505	COG2208	phosphoserine phosphatase activity
D0819_RS19510	COG1366	Belongs to the anti-sigma-factor antagonist family
D0819_RS19515	COG2172	sigma factor antagonist activity
D0819_RS19520	COG1191	sigma factor activity
D0819_RS19525	COG2208	phosphoserine phosphatase activity
D0819_RS19540	COG1673	EVE domain
D0819_RS19545	COG1846	Transcriptional regulator
D0819_RS19550	COG2183	response to ionizing radiation
D0819_RS19560	COG3091	SprT-like family
D0819_RS19600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D0819_RS19605	COG1522	sequence-specific DNA binding
D0819_RS19610	COG1522	sequence-specific DNA binding
D0819_RS19615	COG1335	isochorismatase
D0819_RS19620	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
D0819_RS19625	COG2814	Major facilitator Superfamily
D0819_RS19640	COG5444	nuclease activity
D0819_RS19650	COG3239	Fatty acid desaturase
D0819_RS19655	COG1278	Cold shock
D0819_RS19660	COG1329	Transcriptional regulator
D0819_RS19670	COG1917	Cupin 2, conserved barrel domain protein
D0819_RS19670	COG2207	Transcriptional regulator
D0819_RS19675	COG0697	spore germination
D0819_RS19680	COG3708	Transcriptional regulator
D0819_RS19680	COG2207	Transcriptional regulator
D0819_RS19685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D0819_RS19690	COG0477	Major facilitator Superfamily
D0819_RS19700	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
D0819_RS19715	COG0697	spore germination
D0819_RS19720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D0819_RS19725	COG2030	dehydratase
D0819_RS19730	COG3545	Serine hydrolase
D0819_RS19735	COG1733	regulation of RNA biosynthetic process
D0819_RS19740	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D0819_RS19745	COG0640	Transcriptional regulator
D0819_RS19750	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D0819_RS19760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D0819_RS19765	COG1316	TRANSCRIPTIONal
D0819_RS19780	COG5002	protein histidine kinase activity
D0819_RS19785	COG0745	RESPONSE REGULATOR receiver
D0819_RS19790	COG0697	spore germination
D0819_RS19795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D0819_RS19800	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D0819_RS19805	COG0640	Transcriptional regulator
D0819_RS19810	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D0819_RS19825	COG4585	Histidine kinase
D0819_RS19830	COG2197	response regulator
D0819_RS19835	COG2409	Drug exporters of the RND superfamily
D0819_RS19840	COG1811	Na channel or pump
D0819_RS19845	COG0789	Transcriptional regulator
D0819_RS19845	COG4978	Transcriptional regulator
D0819_RS19850	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D0819_RS19855	COG0778	Nitroreductase
D0819_RS19860	COG0346	lactoylglutathione lyase activity
D0819_RS19865	COG2259	Doxx family
D0819_RS19870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D0819_RS19890	COG2323	membrane
D0819_RS19895	COG0071	Belongs to the small heat shock protein (HSP20) family
D0819_RS19910	COG1309	transcriptional regulator
D0819_RS19925	COG0488	(ABC) transporter
D0819_RS19930	COG1113	amino acid transport
D0819_RS19935	COG2318	DinB family
D0819_RS19940	COG1846	Transcriptional regulator
D0819_RS19945	COG2409	Drug exporters of the RND superfamily
D0819_RS19945	COG1033	growth of symbiont in host cell
D0819_RS19950	COG0778	Nitroreductase
D0819_RS19955	COG1846	Transcriptional regulator
D0819_RS19960	COG2814	Major facilitator Superfamily
D0819_RS19965	COG0730	response to heat
D0819_RS19970	COG1802	Transcriptional regulator
D0819_RS19975	COG3858	chitin binding
D0819_RS19975	COG1388	LysM domain
D0819_RS19980	COG1819	glycosyl
D0819_RS19990	COG1785	Belongs to the alkaline phosphatase family
D0819_RS19995	COG5646	InterPro IPR014922
D0819_RS20005	COG0454	-acetyltransferase
D0819_RS20010	COG1078	dGTPase activity
D0819_RS20015	COG1388	LysM domain
D0819_RS20020	COG2814	Major facilitator Superfamily
D0819_RS20025	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D0819_RS20030	COG1447	Phosphotransferase system cellobiose-specific component IIA
D0819_RS20035	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D0819_RS20040	COG2723	6-phospho-beta-galactosidase activity
D0819_RS20045	COG2188	Transcriptional regulator
D0819_RS20050	COG1940	carbohydrate kinase activity
D0819_RS20055	COG1482	cell wall glycoprotein biosynthetic process
D0819_RS20060	COG4124	Belongs to the glycosyl hydrolase 26 family
D0819_RS20105	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
D0819_RS20110	COG0802	atpase or kinase
D0819_RS20115	COG1214	PFAM Peptidase M22, glycoprotease
D0819_RS20120	COG0456	acetyltransferase
D0819_RS20125	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
D0819_RS20130	COG0488	(ABC) transporter
D0819_RS20135	COG0315	cyclic pyranopterin monophosphate synthase activity
D0819_RS20140	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
D0819_RS20145	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D0819_RS20150	COG0805	protein transport
D0819_RS20160	COG1266	CAAX protease self-immunity
D0819_RS20170	COG0459	protein refolding
D0819_RS20220	COG0457	Tetratricopeptide repeat
D0819_RS20225	COG1063	alcohol dehydrogenase
D0819_RS20230	COG2211	Major facilitator Superfamily
D0819_RS20235	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D0819_RS20240	COG1842	Phage shock protein A
D0819_RS20245	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D0819_RS20250	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
D0819_RS20255	COG4260	virion core protein, lumpy skin disease virus
D0819_RS20265	COG2814	Major facilitator Superfamily
D0819_RS20270	COG1063	alcohol dehydrogenase
D0819_RS20275	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
D0819_RS20280	COG0823	Involved in the tonB-independent uptake of proteins
D0819_RS20295	COG2267	carboxylic ester hydrolase activity
D0819_RS20305	COG2132	Multicopper oxidase
D0819_RS20310	COG1113	amino acid transport
D0819_RS20320	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D0819_RS20325	COG0714	Associated with various cellular activities
D0819_RS20330	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
D0819_RS20335	COG1305	Transglutaminase-like
D0819_RS20340	COG0519	Catalyzes the synthesis of GMP from XMP
D0819_RS20340	COG0518	GMP synthase (glutamine-hydrolyzing) activity
D0819_RS20355	COG2252	PERMEase
D0819_RS20360	COG3064	Membrane
D0819_RS20370	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
D0819_RS20380	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
D0819_RS20385	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
D0819_RS20390	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
D0819_RS20395	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
D0819_RS20400	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D0819_RS20405	COG0047	phosphoribosylformylglycinamidine synthase activity
D0819_RS20410	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D0819_RS20415	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
D0819_RS20420	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
D0819_RS20425	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
D0819_RS20430	COG0138	bifunctional purine biosynthesis protein purh
D0819_RS20435	COG0151	Belongs to the GarS family
D0819_RS20440	COG1522	sequence-specific DNA binding
D0819_RS20445	COG0531	amino acid
D0819_RS20455	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
D0819_RS20460	COG1470	cell adhesion involved in biofilm formation
D0819_RS20465	COG4496	protein, YerC YecD
D0819_RS20470	COG0069	glutamate synthase activity
D0819_RS20475	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
D0819_RS20480	COG0210	DNA helicase
D0819_RS20485	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
D0819_RS20490	COG4851	CamS sex pheromone cAM373 precursor
D0819_RS20495	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D0819_RS20500	COG1285	pathogenesis
D0819_RS20505	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D0819_RS20510	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D0819_RS20515	COG0154	amidase activity
D0819_RS20520	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D0819_RS20525	COG1309	transcriptional regulator
D0819_RS20530	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D0819_RS20535	COG1597	lipid kinase activity
D0819_RS20540	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D0819_RS20570	COG5444	nuclease activity
D0819_RS20585	COG0457	Tetratricopeptide repeat
D0819_RS20595	COG0217	transcriptional regulatory protein
D0819_RS20605	COG1309	transcriptional regulator
D0819_RS20610	COG3631	Ketosteroid isomerase-related protein
D0819_RS20615	COG0702	epimerase
D0819_RS20630	COG3546	catalase activity
D0819_RS20635	COG0454	-acetyltransferase
D0819_RS20645	COG5578	integral membrane protein
D0819_RS20650	COG2972	Histidine kinase
D0819_RS20655	COG4753	response regulator
D0819_RS20655	COG2207	Transcriptional regulator
D0819_RS20660	COG1653	transport
D0819_RS20665	COG1175	transmembrane transport
D0819_RS20670	COG0395	ABC-type sugar transport system, permease component
D0819_RS20675	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
D0819_RS20680	COG2207	Transcriptional regulator
D0819_RS20685	COG2755	lipolytic protein G-D-S-L family
D0819_RS20695	COG5578	integral membrane protein
D0819_RS20700	COG3401	FG-GAP repeat protein
D0819_RS20705	COG3401	FG-GAP repeat protein
D0819_RS20710	COG2755	lipolytic protein G-D-S-L family
D0819_RS20715	COG1874	Beta-galactosidase
D0819_RS20725	COG1653	transport
D0819_RS20730	COG4209	transmembrane transport
D0819_RS20735	COG0395	ABC-type sugar transport system, permease component
D0819_RS20740	COG1486	melibiose metabolic process
D0819_RS20745	COG2323	membrane
D0819_RS20750	COG2329	Antibiotic biosynthesis monooxygenase
D0819_RS20755	COG0346	lactoylglutathione lyase activity
D0819_RS20770	COG5583	Uncharacterized small protein (DUF2292)
D0819_RS20775	COG0670	Belongs to the BI1 family
D0819_RS20785	COG1846	Transcriptional regulator
D0819_RS20790	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D0819_RS20810	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D0819_RS20810	COG2124	cytochrome p450
D0819_RS20815	COG1368	sulfuric ester hydrolase activity
D0819_RS20820	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
D0819_RS20825	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D0819_RS20830	COG1442	glycosyl transferase family 8
D0819_RS20835	COG1216	Glycosyl transferase, family 2
D0819_RS20840	COG1442	glycosyl transferase family 8
D0819_RS20845	COG2223	nitrite transmembrane transporter activity
D0819_RS20850	COG1011	Hydrolase
D0819_RS20855	COG0531	amino acid
D0819_RS20860	COG1012	belongs to the aldehyde dehydrogenase family
D0819_RS20865	COG0840	transmembrane signaling receptor activity
D0819_RS20870	COG0488	(ABC) transporter
D0819_RS20880	COG0789	Transcriptional regulator
D0819_RS20885	COG2814	Major facilitator Superfamily
D0819_RS20890	COG1404	Belongs to the peptidase S8 family
D0819_RS20910	COG0488	(ABC) transporter
D0819_RS20915	COG0513	Belongs to the DEAD box helicase family
D0819_RS20920	COG0456	acetyltransferase
D0819_RS20925	COG2130	NADP-dependent
D0819_RS20930	COG1120	ATPase activity
D0819_RS20935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0819_RS20940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0819_RS20945	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
D0819_RS20960	COG3866	Pectate lyase
D0819_RS20965	COG0471	metal ion transport
D0819_RS20970	COG3290	protein histidine kinase activity
D0819_RS20975	COG4565	transcriptional regulatory protein
D0819_RS20980	COG3181	Tripartite tricarboxylate transporter family receptor
D0819_RS20985	COG2851	Citrate transporter
D0819_RS20990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D0819_RS20995	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
D0819_RS21000	COG1254	Belongs to the acylphosphatase family
D0819_RS21005	COG2258	MOSC domain
D0819_RS21025	COG0024	Methionine aminopeptidase
D0819_RS21030	COG1263	PTS System
D0819_RS21030	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0819_RS21035	COG1368	sulfuric ester hydrolase activity
D0819_RS21050	COG1115	amino acid carrier protein
D0819_RS21055	COG0531	amino acid
D0819_RS21070	COG0697	spore germination
D0819_RS21075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0819_RS21075	COG1263	PTS System
D0819_RS21080	COG0366	Alpha amylase catalytic
D0819_RS21085	COG2188	Transcriptional regulator
D0819_RS21090	COG0778	Nitroreductase
D0819_RS21095	COG0737	Belongs to the 5'-nucleotidase family
D0819_RS21100	COG0693	protein deglycase activity
D0819_RS21105	COG2814	Major facilitator Superfamily
D0819_RS21110	COG4840	Belongs to the UPF0435 family
D0819_RS21115	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D0819_RS21120	COG4980	gas vesicle protein
D0819_RS21125	COG1295	ribonuclease BN
D0819_RS21130	COG0477	Major facilitator Superfamily
D0819_RS21135	COG0387	Pfam Sodium calcium exchanger
D0819_RS21145	COG0668	transmembrane transport
D0819_RS21150	COG0535	radical SAM domain protein
D0819_RS21160	COG0726	polysaccharide deacetylase
D0819_RS21165	COG2084	Dehydrogenase
D0819_RS21170	COG0598	Magnesium transport protein CorA
D0819_RS21175	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
D0819_RS21180	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D0819_RS21195	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D0819_RS21200	COG4637	Psort location Cytoplasmic, score
D0819_RS21205	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D0819_RS21210	COG0022	dehydrogenase e1 component
D0819_RS21215	COG0508	dehydrogenase complex catalyzes the overall conversion of
D0819_RS21220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D0819_RS21225	COG3284	Transcriptional regulator
D0819_RS21235	COG1742	UPF0060 membrane protein
D0819_RS21255	COG4842	Belongs to the WXG100 family
D0819_RS21260	COG1486	melibiose metabolic process
D0819_RS21265	COG1737	Transcriptional regulator
D0819_RS21270	COG1263	PTS System
D0819_RS21270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0819_RS21275	COG5434	Belongs to the glycosyl hydrolase 28 family
D0819_RS21280	COG1132	(ABC) transporter
D0819_RS21285	COG1132	(ABC) transporter
D0819_RS21290	COG2259	Doxx family
D0819_RS21295	COG2514	catechol 2,3-dioxygenase activity
D0819_RS21300	COG4585	Histidine kinase
D0819_RS21305	COG2197	response regulator
D0819_RS21310	COG1131	(ABC) transporter
D0819_RS21315	COG1511	domain protein
D0819_RS21315	COG0842	Transport permease protein
D0819_RS21320	COG0842	Transport permease protein
D0819_RS21325	COG1695	Transcriptional regulator
D0819_RS21330	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
D0819_RS21335	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
D0819_RS21340	COG1309	transcriptional regulator
D0819_RS21350	COG2318	DinB family
D0819_RS21355	COG2814	Major facilitator Superfamily
D0819_RS21360	COG1846	Transcriptional regulator
D0819_RS21365	COG0392	lysyltransferase activity
D0819_RS21365	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
D0819_RS21370	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D0819_RS21375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0819_RS21380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0819_RS21385	COG0384	phenazine biosynthesis protein PhzF
D0819_RS21390	COG0778	Nitroreductase
D0819_RS21405	COG1090	epimerase
D0819_RS21410	COG2137	regulation of response to DNA damage stimulus
D0819_RS21420	COG2814	Major facilitator Superfamily
D0819_RS21435	COG3103	Sh3 type 3 domain protein
D0819_RS21440	COG5658	integral membrane protein
D0819_RS21445	COG0596	Alpha beta hydrolase
D0819_RS21450	COG0463	Glycosyl transferase, family 2
D0819_RS21455	COG4485	Bacterial membrane protein, YfhO
D0819_RS21460	COG1988	membrane-bound metal-dependent
D0819_RS21465	COG1194	a g-specific adenine glycosylase
D0819_RS21475	COG1028	Short-chain dehydrogenase reductase Sdr
D0819_RS21490	COG3557	Belongs to the UPF0374 family
D0819_RS21495	COG1132	(ABC) transporter
D0819_RS21500	COG4129	membrane
D0819_RS21505	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D0819_RS21510	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D0819_RS21515	COG0735	belongs to the Fur family