locus-tag	class	description
JWY35_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JWY35_RS00010	COG0592	DNA-directed DNA polymerase activity
JWY35_RS00015	COG2501	S4 domain
JWY35_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JWY35_RS00030	COG0187	DNA topoisomerase II activity
JWY35_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JWY35_RS00070	COG0516	GMP reductase activity
JWY35_RS00070	COG0517	IMP dehydrogenase activity
JWY35_RS00075	COG1686	Belongs to the peptidase S11 family
JWY35_RS00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
JWY35_RS00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
JWY35_RS00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JWY35_RS00100	COG1428	Deoxynucleoside kinase
JWY35_RS00105	COG1428	Deoxynucleoside kinase
JWY35_RS00110	COG1388	LysM domain
JWY35_RS00110	COG3858	chitin binding
JWY35_RS00115	COG1335	isochorismatase
JWY35_RS00120	COG0590	tRNA wobble adenosine to inosine editing
JWY35_RS00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JWY35_RS00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JWY35_RS00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JWY35_RS00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
JWY35_RS00190	COG3853	Toxic anion resistance protein (TelA)
JWY35_RS00195	COG1982	Orn Lys Arg decarboxylase major
JWY35_RS00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JWY35_RS00205	COG3870	Protein conserved in bacteria
JWY35_RS00210	COG1728	Protein conserved in bacteria
JWY35_RS00215	COG0470	DNA polymerase III
JWY35_RS00220	COG1774	PSP1 C-terminal conserved region
JWY35_RS00225	COG4467	Involved in initiation control of chromosome replication
JWY35_RS00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JWY35_RS00235	COG2827	Endonuclease containing a URI domain
JWY35_RS00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JWY35_RS00245	COG2002	toxin-antitoxin pair type II binding
JWY35_RS00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JWY35_RS00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JWY35_RS00255	COG0084	hydrolase, TatD family'
JWY35_RS00260	COG3583	domain protein
JWY35_RS00260	COG3584	3D domain protein
JWY35_RS00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JWY35_RS00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JWY35_RS00280	COG4466	Protein conserved in bacteria
JWY35_RS00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JWY35_RS00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JWY35_RS00300	COG0251	oxidation-reduction process
JWY35_RS00305	COG2088	sporulation resulting in formation of a cellular spore
JWY35_RS00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JWY35_RS00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JWY35_RS00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JWY35_RS00325	COG0193	aminoacyl-tRNA hydrolase activity
JWY35_RS00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JWY35_RS00340	COG2002	toxin-antitoxin pair type II binding
JWY35_RS00345	COG2244	polysaccharide biosynthetic process
JWY35_RS00350	COG3956	TIGRFAM MazG family protein
JWY35_RS00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JWY35_RS00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
JWY35_RS00375	COG1098	S1 RNA binding domain
JWY35_RS00390	COG2208	phosphoserine phosphatase activity
JWY35_RS00395	COG2304	oxidoreductase activity
JWY35_RS00400	COG0515	serine threonine protein kinase
JWY35_RS00405	COG0037	tRNA processing
JWY35_RS00410	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
JWY35_RS00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JWY35_RS00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
JWY35_RS00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JWY35_RS00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JWY35_RS00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JWY35_RS00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JWY35_RS00445	COG0512	Glutamine amidotransferase of anthranilate synthase
JWY35_RS00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JWY35_RS00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JWY35_RS00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JWY35_RS00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JWY35_RS00470	COG1396	sequence-specific DNA binding
JWY35_RS00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JWY35_RS00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JWY35_RS00560	COG4463	regulation of RNA biosynthetic process
JWY35_RS00565	COG3880	PFAM UvrB UvrC protein
JWY35_RS00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
JWY35_RS00575	COG0542	response to heat
JWY35_RS00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JWY35_RS00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
JWY35_RS00590	COG4956	integral membrane protein (PIN domain superfamily)
JWY35_RS00595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JWY35_RS00600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
JWY35_RS00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JWY35_RS00610	COG1045	serine acetyltransferase
JWY35_RS00615	COG0215	cysteine-tRNA ligase activity
JWY35_RS00620	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JWY35_RS00625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JWY35_RS00630	COG3688	RNA-binding protein containing a PIN domain
JWY35_RS00635	COG1595	DNA-templated transcription, initiation
JWY35_RS00645	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JWY35_RS00650	COG0250	Participates in transcription elongation, termination and antitermination
JWY35_RS00660	COG0081	regulation of translation
JWY35_RS00665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JWY35_RS00675	COG2813	Specifically methylates the guanine in position
JWY35_RS00680	COG0085	RNA polymerase activity
JWY35_RS00685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JWY35_RS00690	COG1358	cellular component organization or biogenesis
JWY35_RS00695	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JWY35_RS00700	COG0049	tRNA binding
JWY35_RS00705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JWY35_RS00710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JWY35_RS00715	COG0596	Alpha beta hydrolase
JWY35_RS00725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JWY35_RS00730	COG0088	Forms part of the polypeptide exit tunnel
JWY35_RS00740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JWY35_RS00755	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JWY35_RS00760	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JWY35_RS00770	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JWY35_RS00775	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JWY35_RS00785	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JWY35_RS00795	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JWY35_RS00800	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JWY35_RS00805	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JWY35_RS00810	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JWY35_RS00820	COG0200	Binds to the 23S rRNA
JWY35_RS00825	COG0201	protein transport
JWY35_RS00830	COG0563	adenylate kinase activity
JWY35_RS00835	COG0024	Methionine aminopeptidase
JWY35_RS00840	COG2163	COG2163 Ribosomal protein L14E L6E L27E
JWY35_RS00850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JWY35_RS00855	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JWY35_RS00860	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JWY35_RS00865	COG0202	RNA polymerase activity
JWY35_RS00870	COG0203	ribosomal protein L17
JWY35_RS00875	COG1122	ATPase activity
JWY35_RS00880	COG1122	ATPase activity
JWY35_RS00885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JWY35_RS00890	COG0101	tRNA pseudouridine synthase activity
JWY35_RS00895	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JWY35_RS00900	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JWY35_RS00905	COG2226	methyltransferase
JWY35_RS00915	COG0860	N-Acetylmuramoyl-L-alanine amidase
JWY35_RS00920	COG0489	protein tyrosine kinase activity
JWY35_RS00930	COG2194	sulfuric ester hydrolase activity
JWY35_RS00935	COG0726	polysaccharide deacetylase
JWY35_RS01020	COG0659	secondary active sulfate transmembrane transporter activity
JWY35_RS01025	COG0385	Bile acid
JWY35_RS01030	COG2819	hydrolase of the alpha beta superfamily
JWY35_RS01035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JWY35_RS01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JWY35_RS01045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JWY35_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JWY35_RS01050	COG2207	Transcriptional regulator
JWY35_RS01055	COG3876	Protein conserved in bacteria
JWY35_RS01060	COG1472	Belongs to the glycosyl hydrolase 3 family
JWY35_RS01065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JWY35_RS01070	COG1263	PTS System
JWY35_RS01070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JWY35_RS01075	COG1737	Transcriptional regulator
JWY35_RS01080	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JWY35_RS01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JWY35_RS01090	COG1683	Conserved Protein
JWY35_RS01120	COG1595	DNA-templated transcription, initiation
JWY35_RS01125	COG5662	AntiSigma factor
JWY35_RS01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JWY35_RS01135	COG4856	YbbR-like protein
JWY35_RS01140	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JWY35_RS01145	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JWY35_RS01160	COG2169	Transcriptional regulator
JWY35_RS01165	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JWY35_RS01170	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JWY35_RS01175	COG3002	Belongs to the UPF0753 family
JWY35_RS01180	COG0288	reversible hydration of carbon dioxide
JWY35_RS01190	COG5609	conserved protein (DUF2294)
JWY35_RS01200	COG0642	Histidine kinase
JWY35_RS01210	COG0515	serine threonine protein kinase
JWY35_RS01225	COG1113	amino acid transport
JWY35_RS01240	COG2602	Beta-lactamase
JWY35_RS01245	COG2124	cytochrome p450
JWY35_RS01255	COG0531	amino acid
JWY35_RS01260	COG0584	glycerophosphoryl diester phosphodiesterase
JWY35_RS01265	COG2271	Major facilitator Superfamily
JWY35_RS01275	COG0456	acetyltransferase
JWY35_RS01275	COG1846	Transcriptional regulator
JWY35_RS01290	COG3409	Peptidoglycan-binding domain 1 protein
JWY35_RS01295	COG0697	spore germination
JWY35_RS01300	COG1917	Cupin 2, conserved barrel domain protein
JWY35_RS01300	COG2207	Transcriptional regulator
JWY35_RS01325	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
JWY35_RS01330	COG3591	Belongs to the peptidase S1B family
JWY35_RS01340	COG0596	Alpha beta hydrolase
JWY35_RS01345	COG1183	phosphatidylcholine synthase activity
JWY35_RS01350	COG0586	Pfam SNARE associated Golgi protein
JWY35_RS01355	COG0688	phosphatidylethanolamine metabolic process
JWY35_RS01365	COG2312	Erythromycin esterase
JWY35_RS01370	COG2207	Transcriptional regulator
JWY35_RS01375	COG1054	Belongs to the UPF0176 family
JWY35_RS01380	COG1301	dicarboxylic acid transport
JWY35_RS01385	COG1263	PTS System
JWY35_RS01385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JWY35_RS01385	COG2190	(PTS) system
JWY35_RS01390	COG0363	glucosamine-6-phosphate deaminase activity
JWY35_RS01395	COG2188	Transcriptional regulator
JWY35_RS01405	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JWY35_RS01410	COG0833	amino acid
JWY35_RS01415	COG2040	homocysteine
JWY35_RS01425	COG2066	Belongs to the glutaminase family
JWY35_RS01430	COG4191	Histidine kinase
JWY35_RS01435	COG0784	Response regulator, receiver
JWY35_RS01440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JWY35_RS01445	COG1012	belongs to the aldehyde dehydrogenase family
JWY35_RS01450	COG2271	Major facilitator Superfamily
JWY35_RS01455	COG4948	Mandelate Racemase Muconate Lactonizing
JWY35_RS01460	COG2186	Transcriptional regulator
JWY35_RS01465	COG2721	sulfolactate sulfo-lyase activity
JWY35_RS01470	COG3173	Aminoglycoside phosphotransferase
JWY35_RS01480	COG0697	spore germination
JWY35_RS01485	COG0745	RESPONSE REGULATOR receiver
JWY35_RS01490	COG2205	protein histidine kinase activity
JWY35_RS01495	COG1131	(ABC) transporter
JWY35_RS01515	COG3773	Cell wall hydrolase
JWY35_RS01520	COG2304	oxidoreductase activity
JWY35_RS01530	COG3540	Alkaline phosphatase
JWY35_RS01535	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JWY35_RS01540	COG0805	protein transport
JWY35_RS01545	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
JWY35_RS01550	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JWY35_RS01555	COG0477	Major facilitator Superfamily
JWY35_RS01560	COG1309	transcriptional regulator
JWY35_RS01565	COG0252	asparaginase activity
JWY35_RS01570	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
JWY35_RS01575	COG1714	RDD family
JWY35_RS01580	COG1405	negative regulation of cell septum assembly
JWY35_RS01580	COG3012	SEC-C Motif Domain Protein
JWY35_RS01590	COG3279	Response regulator of the LytR AlgR family
JWY35_RS01600	COG1668	transmembrane transport
JWY35_RS01605	COG0667	Aldo Keto reductase
JWY35_RS01620	COG1595	DNA-templated transcription, initiation
JWY35_RS01625	COG1595	DNA-templated transcription, initiation
JWY35_RS01630	COG1876	peptidase activity
JWY35_RS01640	COG1028	Short-chain dehydrogenase reductase Sdr
JWY35_RS01645	COG0366	Alpha amylase catalytic
JWY35_RS01650	COG0803	Belongs to the bacterial solute-binding protein 9 family
JWY35_RS01655	COG1121	(ABC) transporter
JWY35_RS01660	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JWY35_RS01670	COG2310	stress, protein
JWY35_RS01675	COG2310	stress, protein
JWY35_RS01680	COG2310	stress, protein
JWY35_RS01685	COG0861	Integral membrane protein TerC family
JWY35_RS01695	COG3853	Toxic anion resistance protein (TelA)
JWY35_RS01705	COG0477	Major facilitator Superfamily
JWY35_RS01710	COG2814	Major facilitator Superfamily
JWY35_RS01715	COG0640	Transcriptional regulator
JWY35_RS01720	COG0517	IMP dehydrogenase activity
JWY35_RS01720	COG4175	Glycine betaine
JWY35_RS01725	COG4176	ABC-type proline glycine betaine transport system permease component
JWY35_RS01730	COG2113	Glycine betaine
JWY35_RS01735	COG1473	amidohydrolase
JWY35_RS01740	COG1288	antiporter activity
JWY35_RS01755	COG0039	L-malate dehydrogenase activity
JWY35_RS01770	COG3403	YqcI/YcgG family
JWY35_RS01785	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JWY35_RS01790	COG1660	Displays ATPase and GTPase activities
JWY35_RS01795	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JWY35_RS01805	COG2226	methyltransferase
JWY35_RS01810	COG0583	DNA-binding transcription factor activity
JWY35_RS01815	COG3458	cephalosporin-C deacetylase activity
JWY35_RS01820	COG3541	Predicted nucleotidyltransferase
JWY35_RS01825	COG0506	proline dehydrogenase activity
JWY35_RS01830	COG1012	belongs to the aldehyde dehydrogenase family
JWY35_RS01835	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JWY35_RS01840	COG2508	Transcriptional regulator
JWY35_RS01845	COG3689	TIGRFAM TIGR03943 family protein
JWY35_RS01850	COG0701	Predicted permease
JWY35_RS01855	COG2267	carboxylic ester hydrolase activity
JWY35_RS01860	COG0492	ferredoxin-NADP+ reductase activity
JWY35_RS01865	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JWY35_RS01865	COG1587	Uroporphyrinogen-III synthase
JWY35_RS01870	COG2146	nitrite reductase [NAD(P)H] activity
JWY35_RS01875	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JWY35_RS01880	COG0243	molybdopterin cofactor binding
JWY35_RS01885	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JWY35_RS01890	COG2223	nitrite transmembrane transporter activity
JWY35_RS01900	COG1376	ErfK ybiS ycfS ynhG family protein
JWY35_RS01915	COG0765	amino acid transport
JWY35_RS01920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JWY35_RS01930	COG1714	RDD family
JWY35_RS01940	COG1846	Transcriptional regulator
JWY35_RS01955	COG2723	6-phospho-beta-galactosidase activity
JWY35_RS01965	COG3209	COG3209 Rhs family protein
JWY35_RS01975	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
JWY35_RS01980	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
JWY35_RS01985	COG1733	regulation of RNA biosynthetic process
JWY35_RS01990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JWY35_RS02010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JWY35_RS02015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JWY35_RS02020	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
JWY35_RS02025	COG2814	Major facilitator Superfamily
JWY35_RS02035	COG0697	spore germination
JWY35_RS02040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JWY35_RS02050	COG2364	Membrane
JWY35_RS02055	COG1126	abc transporter atp-binding protein
JWY35_RS02060	COG0765	amino acid transport
JWY35_RS02065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JWY35_RS02070	COG0583	DNA-binding transcription factor activity
JWY35_RS02075	COG0163	prenyltransferase activity
JWY35_RS02080	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
JWY35_RS02095	COG0596	Alpha beta hydrolase
JWY35_RS02100	COG3104	oligopeptide transport
JWY35_RS02105	COG5434	Belongs to the glycosyl hydrolase 28 family
JWY35_RS02115	COG0697	spore germination
JWY35_RS02125	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
JWY35_RS02130	COG1136	(ABC) transporter
JWY35_RS02135	COG0577	efflux transmembrane transporter activity
JWY35_RS02140	COG0745	RESPONSE REGULATOR receiver
JWY35_RS02145	COG3850	Histidine kinase
JWY35_RS02145	COG5002	protein histidine kinase activity
JWY35_RS02150	COG0457	Tetratricopeptide repeat
JWY35_RS02170	COG0527	aspartate kinase activity
JWY35_RS02175	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JWY35_RS02180	COG4605	iron ion homeostasis
JWY35_RS02185	COG4604	ABC transporter, ATP-binding protein
JWY35_RS02190	COG4607	ABC-type enterochelin transport system periplasmic component
JWY35_RS02200	COG2814	Major facilitator Superfamily
JWY35_RS02205	COG1309	transcriptional regulator
JWY35_RS02210	COG0778	Nitroreductase
JWY35_RS02215	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
JWY35_RS02220	COG0640	Transcriptional regulator
JWY35_RS02225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JWY35_RS02230	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JWY35_RS02235	COG1012	belongs to the aldehyde dehydrogenase family
JWY35_RS02240	COG4975	Glucose uptake
JWY35_RS02245	COG1028	Short-chain dehydrogenase reductase Sdr
JWY35_RS02250	COG4549	nuclear export factor GLE1
JWY35_RS02255	COG1276	copper resistance
JWY35_RS02255	COG2372	response to copper ion
JWY35_RS02260	COG1349	DNA-binding transcription factor activity
JWY35_RS02270	COG2213	PTS system mannitol-specific
JWY35_RS02275	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JWY35_RS02280	COG0246	Mannitol dehydrogenase
JWY35_RS02285	COG0473	3-isopropylmalate dehydrogenase activity
JWY35_RS02290	COG0681	Belongs to the peptidase S26 family
JWY35_RS02300	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JWY35_RS02310	COG0561	phosphatase activity
JWY35_RS02315	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JWY35_RS02320	COG1914	H( )-stimulated, divalent metal cation uptake system
JWY35_RS02325	COG4336	lyase activity
JWY35_RS02330	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JWY35_RS02335	COG1984	allophanate hydrolase subunit 2
JWY35_RS02340	COG1414	Transcriptional regulator
JWY35_RS02345	COG2755	lipolytic protein G-D-S-L family
JWY35_RS02355	COG2329	Antibiotic biosynthesis monooxygenase
JWY35_RS02360	COG0768	penicillin binding
JWY35_RS02365	COG4989	oxidoreductase activity
JWY35_RS02370	COG3711	transcriptional antiterminator
JWY35_RS02375	COG0318	PFAM AMP-dependent synthetase and ligase
JWY35_RS02380	COG2226	methyltransferase
JWY35_RS02385	COG1028	Short-chain dehydrogenase reductase Sdr
JWY35_RS02390	COG1917	Cupin 2, conserved barrel domain protein
JWY35_RS02395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JWY35_RS02400	COG3871	stress protein (general stress protein 26)
JWY35_RS02410	COG2814	Major facilitator Superfamily
JWY35_RS02415	COG1522	sequence-specific DNA binding
JWY35_RS02420	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JWY35_RS02420	COG0551	DNA topoisomerase type I activity
JWY35_RS02425	COG0494	nUDIX hydrolase
JWY35_RS02430	COG0028	Belongs to the TPP enzyme family
JWY35_RS02455	COG1914	H( )-stimulated, divalent metal cation uptake system
JWY35_RS02460	COG2261	transglycosylase associated protein
JWY35_RS02465	COG4876	unkown
JWY35_RS02470	COG2217	Heavy metal translocating P-type atpase
JWY35_RS02475	COG3729	General stress protein
JWY35_RS02480	COG0662	Cupin 2, conserved barrel domain protein
JWY35_RS02485	COG2329	Antibiotic biosynthesis monooxygenase
JWY35_RS02490	COG3546	catalase activity
JWY35_RS02495	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JWY35_RS02500	COG3290	protein histidine kinase activity
JWY35_RS02505	COG4565	transcriptional regulatory protein
JWY35_RS02510	COG1301	dicarboxylic acid transport
JWY35_RS02515	COG0628	permease
JWY35_RS02525	COG1131	(ABC) transporter
JWY35_RS02530	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
JWY35_RS02540	COG1960	acyl-CoA dehydrogenase activity
JWY35_RS02555	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JWY35_RS02560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JWY35_RS02565	COG1181	Belongs to the D-alanine--D-alanine ligase family
JWY35_RS02570	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JWY35_RS02575	COG0513	Belongs to the DEAD box helicase family
JWY35_RS02580	COG3402	PFAM membrane-flanked domain
JWY35_RS02585	COG3428	Bacterial PH domain
JWY35_RS02590	COG0705	Rhomboid family
JWY35_RS02595	COG0736	holo-[acyl-carrier-protein] synthase activity
JWY35_RS02600	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
JWY35_RS02605	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JWY35_RS02610	COG0864	Transcriptional regulator
JWY35_RS02615	COG2337	Toxic component of a toxin-antitoxin (TA) module
JWY35_RS02620	COG1366	Belongs to the anti-sigma-factor antagonist family
JWY35_RS02625	COG1366	Belongs to the anti-sigma-factor antagonist family
JWY35_RS02630	COG2172	sigma factor antagonist activity
JWY35_RS02635	COG2208	phosphoserine phosphatase activity
JWY35_RS02640	COG1366	Belongs to the anti-sigma-factor antagonist family
JWY35_RS02645	COG2172	sigma factor antagonist activity
JWY35_RS02650	COG1191	sigma factor activity
JWY35_RS02655	COG2208	phosphoserine phosphatase activity
JWY35_RS02670	COG1673	EVE domain
JWY35_RS02675	COG1846	Transcriptional regulator
JWY35_RS02680	COG2183	response to ionizing radiation
JWY35_RS02690	COG3091	SprT-like family
JWY35_RS02730	COG0582	viral genome integration into host DNA
JWY35_RS02735	COG2856	Zn peptidase
JWY35_RS02740	COG1396	sequence-specific DNA binding
JWY35_RS02770	COG1674	ftsk spoiiie
JWY35_RS02775	COG2946	Replication initiation factor
JWY35_RS02815	COG0433	COG0433 Predicted ATPase
JWY35_RS02825	COG5644	endopeptidase inhibitor activity
JWY35_RS02835	COG0741	lytic transglycosylase activity
JWY35_RS02835	COG0791	NLP P60 protein
JWY35_RS02850	COG0457	Tetratricopeptide repeat
JWY35_RS02890	COG0583	DNA-binding transcription factor activity
JWY35_RS02895	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JWY35_RS02905	COG5444	nuclease activity
JWY35_RS02910	COG1476	TRANSCRIPTIONal
JWY35_RS02935	COG0693	protein deglycase activity
JWY35_RS02940	COG1278	Cold shock
JWY35_RS02945	COG1329	Transcriptional regulator
JWY35_RS02950	COG0697	spore germination
JWY35_RS02955	COG2207	Transcriptional regulator
JWY35_RS02955	COG1917	Cupin 2, conserved barrel domain protein
JWY35_RS02965	COG3708	Transcriptional regulator
JWY35_RS02965	COG2207	Transcriptional regulator
JWY35_RS02970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JWY35_RS02985	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
JWY35_RS03000	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JWY35_RS03005	COG1309	transcriptional regulator
JWY35_RS03010	COG0697	spore germination
JWY35_RS03015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JWY35_RS03020	COG2030	dehydratase
JWY35_RS03025	COG3545	Serine hydrolase
JWY35_RS03035	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JWY35_RS03040	COG0640	Transcriptional regulator
JWY35_RS03045	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JWY35_RS03055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JWY35_RS03060	COG0697	spore germination
JWY35_RS03065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JWY35_RS03070	COG0076	glutamate decarboxylase activity
JWY35_RS03075	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JWY35_RS03080	COG0640	Transcriptional regulator
JWY35_RS03085	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JWY35_RS03100	COG4585	Histidine kinase
JWY35_RS03105	COG2197	response regulator
JWY35_RS03110	COG2409	Drug exporters of the RND superfamily
JWY35_RS03115	COG0596	Alpha beta hydrolase
JWY35_RS03120	COG1811	Na channel or pump
JWY35_RS03125	COG4978	Transcriptional regulator
JWY35_RS03125	COG0789	Transcriptional regulator
JWY35_RS03130	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JWY35_RS03135	COG0778	Nitroreductase
JWY35_RS03140	COG0346	lactoylglutathione lyase activity
JWY35_RS03145	COG2259	Doxx family
JWY35_RS03150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JWY35_RS03180	COG2323	membrane
JWY35_RS03185	COG0071	Belongs to the small heat shock protein (HSP20) family
JWY35_RS03200	COG1309	transcriptional regulator
JWY35_RS03210	COG0456	acetyltransferase
JWY35_RS03215	COG0488	(ABC) transporter
JWY35_RS03220	COG1113	amino acid transport
JWY35_RS03225	COG2318	DinB family
JWY35_RS03230	COG1846	Transcriptional regulator
JWY35_RS03235	COG1033	growth of symbiont in host cell
JWY35_RS03235	COG2409	Drug exporters of the RND superfamily
JWY35_RS03240	COG0778	Nitroreductase
JWY35_RS03245	COG1846	Transcriptional regulator
JWY35_RS03250	COG2814	Major facilitator Superfamily
JWY35_RS03255	COG0730	response to heat
JWY35_RS03260	COG1802	Transcriptional regulator
JWY35_RS03265	COG1388	LysM domain
JWY35_RS03265	COG3858	chitin binding
JWY35_RS03270	COG1819	glycosyl
JWY35_RS03280	COG1785	Belongs to the alkaline phosphatase family
JWY35_RS03285	COG5646	InterPro IPR014922
JWY35_RS03295	COG0454	-acetyltransferase
JWY35_RS03300	COG1078	dGTPase activity
JWY35_RS03305	COG1388	LysM domain
JWY35_RS03310	COG2814	Major facilitator Superfamily
JWY35_RS03315	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JWY35_RS03330	COG2723	6-phospho-beta-galactosidase activity
JWY35_RS03335	COG2188	Transcriptional regulator
JWY35_RS03340	COG1940	carbohydrate kinase activity
JWY35_RS03350	COG4124	Belongs to the glycosyl hydrolase 26 family
JWY35_RS03395	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
JWY35_RS03400	COG0802	atpase or kinase
JWY35_RS03405	COG1214	PFAM Peptidase M22, glycoprotease
JWY35_RS03410	COG0456	acetyltransferase
JWY35_RS03415	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JWY35_RS03420	COG0488	(ABC) transporter
JWY35_RS03425	COG0315	cyclic pyranopterin monophosphate synthase activity
JWY35_RS03430	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JWY35_RS03435	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JWY35_RS03440	COG0805	protein transport
JWY35_RS03450	COG1266	CAAX protease self-immunity
JWY35_RS03460	COG0459	protein refolding
JWY35_RS03475	COG0457	Tetratricopeptide repeat
JWY35_RS03480	COG1063	alcohol dehydrogenase
JWY35_RS03485	COG2211	Major facilitator Superfamily
JWY35_RS03490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JWY35_RS03500	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JWY35_RS03505	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
JWY35_RS03510	COG4260	virion core protein, lumpy skin disease virus
JWY35_RS03520	COG2814	Major facilitator Superfamily
JWY35_RS03525	COG1063	alcohol dehydrogenase
JWY35_RS03530	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JWY35_RS03535	COG0823	Involved in the tonB-independent uptake of proteins
JWY35_RS03555	COG2267	carboxylic ester hydrolase activity
JWY35_RS03565	COG2132	Multicopper oxidase
JWY35_RS03570	COG1113	amino acid transport
JWY35_RS03580	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JWY35_RS03585	COG0714	Associated with various cellular activities
JWY35_RS03590	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
JWY35_RS03595	COG1305	Transglutaminase-like
JWY35_RS03600	COG0519	Catalyzes the synthesis of GMP from XMP
JWY35_RS03600	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JWY35_RS03610	COG2252	PERMEase
JWY35_RS03615	COG3064	Membrane
JWY35_RS03625	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
JWY35_RS03635	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JWY35_RS03640	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JWY35_RS03645	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JWY35_RS03650	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JWY35_RS03655	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JWY35_RS03660	COG0047	phosphoribosylformylglycinamidine synthase activity
JWY35_RS03665	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JWY35_RS03670	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JWY35_RS03675	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JWY35_RS03680	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JWY35_RS03685	COG0138	bifunctional purine biosynthesis protein purh
JWY35_RS03690	COG0151	Belongs to the GarS family
JWY35_RS03695	COG1522	sequence-specific DNA binding
JWY35_RS03700	COG0531	amino acid
JWY35_RS03710	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JWY35_RS03715	COG1470	cell adhesion involved in biofilm formation
JWY35_RS03720	COG4496	protein, YerC YecD
JWY35_RS03725	COG0069	glutamate synthase activity
JWY35_RS03730	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
JWY35_RS03735	COG0210	DNA helicase
JWY35_RS03740	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JWY35_RS03745	COG4851	CamS sex pheromone cAM373 precursor
JWY35_RS03755	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JWY35_RS03760	COG1285	pathogenesis
JWY35_RS03765	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JWY35_RS03770	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JWY35_RS03775	COG0154	amidase activity
JWY35_RS03780	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JWY35_RS03790	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JWY35_RS03795	COG1597	lipid kinase activity
JWY35_RS03800	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JWY35_RS03805	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JWY35_RS03830	COG5444	nuclease activity
JWY35_RS03840	COG0457	Tetratricopeptide repeat
JWY35_RS03850	COG0217	transcriptional regulatory protein
JWY35_RS03860	COG1309	transcriptional regulator
JWY35_RS03875	COG3546	catalase activity
JWY35_RS03880	COG0454	-acetyltransferase
JWY35_RS03890	COG5578	integral membrane protein
JWY35_RS03895	COG2972	Histidine kinase
JWY35_RS03905	COG1653	transport
JWY35_RS03910	COG1175	transmembrane transport
JWY35_RS03915	COG0395	ABC-type sugar transport system, permease component
JWY35_RS03920	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
JWY35_RS03925	COG2207	Transcriptional regulator
JWY35_RS03930	COG2755	lipolytic protein G-D-S-L family
JWY35_RS03940	COG5578	integral membrane protein
JWY35_RS03945	COG3401	FG-GAP repeat protein
JWY35_RS03950	COG3401	FG-GAP repeat protein
JWY35_RS03955	COG2755	lipolytic protein G-D-S-L family
JWY35_RS03970	COG1653	transport
JWY35_RS03975	COG4209	transmembrane transport
JWY35_RS03980	COG0395	ABC-type sugar transport system, permease component
JWY35_RS03985	COG1486	melibiose metabolic process
JWY35_RS03990	COG2323	membrane
JWY35_RS03995	COG2329	Antibiotic biosynthesis monooxygenase
JWY35_RS04000	COG0346	lactoylglutathione lyase activity
JWY35_RS04015	COG5583	Uncharacterized small protein (DUF2292)
JWY35_RS04020	COG0670	Belongs to the BI1 family
JWY35_RS04035	COG3328	transposase activity
JWY35_RS04045	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JWY35_RS04045	COG2124	cytochrome p450
JWY35_RS04050	COG1368	sulfuric ester hydrolase activity
JWY35_RS04055	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JWY35_RS04060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JWY35_RS04065	COG1442	glycosyl transferase family 8
JWY35_RS04070	COG1216	Glycosyl transferase, family 2
JWY35_RS04075	COG1442	glycosyl transferase family 8
JWY35_RS04080	COG2223	nitrite transmembrane transporter activity
JWY35_RS04085	COG1011	Hydrolase
JWY35_RS04090	COG0531	amino acid
JWY35_RS04095	COG1012	belongs to the aldehyde dehydrogenase family
JWY35_RS04100	COG0840	transmembrane signaling receptor activity
JWY35_RS04105	COG0488	(ABC) transporter
JWY35_RS04115	COG0789	Transcriptional regulator
JWY35_RS04120	COG2814	Major facilitator Superfamily
JWY35_RS04140	COG0488	(ABC) transporter
JWY35_RS04145	COG0513	Belongs to the DEAD box helicase family
JWY35_RS04155	COG3866	Pectate lyase
JWY35_RS04160	COG0471	metal ion transport
JWY35_RS04165	COG3290	protein histidine kinase activity
JWY35_RS04170	COG4565	transcriptional regulatory protein
JWY35_RS04175	COG3181	Tripartite tricarboxylate transporter family receptor
JWY35_RS04180	COG2851	Citrate transporter
JWY35_RS04185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JWY35_RS04190	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
JWY35_RS04195	COG1254	Belongs to the acylphosphatase family
JWY35_RS04200	COG2258	MOSC domain
JWY35_RS04220	COG0024	Methionine aminopeptidase
JWY35_RS04225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JWY35_RS04225	COG1263	PTS System
JWY35_RS04230	COG1368	sulfuric ester hydrolase activity
JWY35_RS04245	COG1115	amino acid carrier protein
JWY35_RS04260	COG1263	PTS System
JWY35_RS04260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JWY35_RS04265	COG0366	Alpha amylase catalytic
JWY35_RS04270	COG2188	Transcriptional regulator
JWY35_RS04275	COG0778	Nitroreductase
JWY35_RS04280	COG0737	Belongs to the 5'-nucleotidase family
JWY35_RS04285	COG0693	protein deglycase activity
JWY35_RS04295	COG2814	Major facilitator Superfamily
JWY35_RS04300	COG4840	Belongs to the UPF0435 family
JWY35_RS04305	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JWY35_RS04310	COG4980	gas vesicle protein
JWY35_RS04315	COG1295	ribonuclease BN
JWY35_RS04320	COG0477	Major facilitator Superfamily
JWY35_RS04325	COG0387	Pfam Sodium calcium exchanger
JWY35_RS04335	COG0668	transmembrane transport
JWY35_RS04340	COG0535	radical SAM domain protein
JWY35_RS04350	COG0726	polysaccharide deacetylase
JWY35_RS04355	COG2084	Dehydrogenase
JWY35_RS04360	COG0598	Magnesium transport protein CorA
JWY35_RS04365	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JWY35_RS04370	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JWY35_RS04380	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JWY35_RS04385	COG4637	Psort location Cytoplasmic, score
JWY35_RS04395	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JWY35_RS04400	COG0022	dehydrogenase e1 component
JWY35_RS04405	COG0508	dehydrogenase complex catalyzes the overall conversion of
JWY35_RS04410	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JWY35_RS04415	COG3284	Transcriptional regulator
JWY35_RS04425	COG1742	UPF0060 membrane protein
JWY35_RS04450	COG4842	Belongs to the WXG100 family
JWY35_RS04455	COG1486	melibiose metabolic process
JWY35_RS04460	COG1737	Transcriptional regulator
JWY35_RS04465	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JWY35_RS04465	COG1263	PTS System
JWY35_RS04470	COG5434	Belongs to the glycosyl hydrolase 28 family
JWY35_RS04475	COG1132	(ABC) transporter
JWY35_RS04480	COG1132	(ABC) transporter
JWY35_RS04485	COG2259	Doxx family
JWY35_RS04490	COG2514	catechol 2,3-dioxygenase activity
JWY35_RS04495	COG1917	Cupin 2, conserved barrel domain protein
JWY35_RS04495	COG4977	sequence-specific DNA binding
JWY35_RS04500	COG2814	Major facilitator Superfamily
JWY35_RS04505	COG1082	Xylose isomerase domain protein TIM barrel
JWY35_RS04515	COG4585	Histidine kinase
JWY35_RS04520	COG2197	response regulator
JWY35_RS04525	COG1131	(ABC) transporter
JWY35_RS04530	COG0842	Transport permease protein
JWY35_RS04530	COG1511	domain protein
JWY35_RS04535	COG0842	Transport permease protein
JWY35_RS04540	COG1695	Transcriptional regulator
JWY35_RS04545	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
JWY35_RS04550	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
JWY35_RS04555	COG1309	transcriptional regulator
JWY35_RS04560	COG2814	Major facilitator Superfamily
JWY35_RS04565	COG2318	DinB family
JWY35_RS04575	COG1846	Transcriptional regulator
JWY35_RS04580	COG0392	lysyltransferase activity
JWY35_RS04580	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JWY35_RS04585	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JWY35_RS04590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JWY35_RS04595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JWY35_RS04600	COG0384	phenazine biosynthesis protein PhzF
JWY35_RS04605	COG0778	Nitroreductase
JWY35_RS04620	COG1090	epimerase
JWY35_RS04625	COG2137	regulation of response to DNA damage stimulus
JWY35_RS04635	COG2814	Major facilitator Superfamily
JWY35_RS04650	COG3103	Sh3 type 3 domain protein
JWY35_RS04655	COG5658	integral membrane protein
JWY35_RS04660	COG0596	Alpha beta hydrolase
JWY35_RS04665	COG0463	Glycosyl transferase, family 2
JWY35_RS04670	COG4485	Bacterial membrane protein, YfhO
JWY35_RS04675	COG1988	membrane-bound metal-dependent
JWY35_RS04680	COG1194	a g-specific adenine glycosylase
JWY35_RS04690	COG1028	Short-chain dehydrogenase reductase Sdr
JWY35_RS04705	COG3557	Belongs to the UPF0374 family
JWY35_RS04710	COG1132	(ABC) transporter
JWY35_RS04715	COG4129	membrane
JWY35_RS04720	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JWY35_RS04725	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JWY35_RS04730	COG0735	belongs to the Fur family
JWY35_RS04840	COG4326	sporulation control protein
JWY35_RS04850	COG5577	PFAM Coat F domain
JWY35_RS04855	COG3340	Belongs to the peptidase S51 family
JWY35_RS04860	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JWY35_RS04875	COG0753	catalase activity
JWY35_RS04880	COG1116	anion transmembrane transporter activity
JWY35_RS04885	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JWY35_RS04890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JWY35_RS04895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JWY35_RS04905	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JWY35_RS04915	COG1476	TRANSCRIPTIONal
JWY35_RS04925	COG3382	B3 4 domain protein
JWY35_RS04930	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JWY35_RS04940	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JWY35_RS04945	COG0789	Transcriptional regulator
JWY35_RS04950	COG1664	Polymer-forming cytoskeletal
JWY35_RS04955	COG1664	Polymer-forming cytoskeletal
JWY35_RS04960	COG2766	serine protein kinase
JWY35_RS04965	COG2718	Belongs to the UPF0229 family
JWY35_RS04970	COG1846	Transcriptional regulator
JWY35_RS04975	COG1566	PFAM secretion protein HlyD family protein
JWY35_RS04980	COG2814	Major facilitator Superfamily
JWY35_RS04985	COG0655	NAD(P)H dehydrogenase (quinone) activity
JWY35_RS05005	COG1725	Transcriptional regulator
JWY35_RS05010	COG1131	(ABC) transporter
JWY35_RS05015	COG1131	(ABC) transporter
JWY35_RS05020	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
JWY35_RS05025	COG1278	Cold shock
JWY35_RS05030	COG1464	Belongs to the NlpA lipoprotein family
JWY35_RS05035	COG3706	GGDEF domain
JWY35_RS05040	COG1823	symporter activity
JWY35_RS05045	COG5444	nuclease activity
JWY35_RS05070	COG0582	viral genome integration into host DNA
JWY35_RS05135	COG5644	endopeptidase inhibitor activity
JWY35_RS05140	COG0741	lytic transglycosylase activity
JWY35_RS05140	COG0791	NLP P60 protein
JWY35_RS05160	COG0457	Tetratricopeptide repeat
JWY35_RS05180	COG4085	toxin activity
JWY35_RS05180	COG1525	nuclease
JWY35_RS05180	COG0737	Belongs to the 5'-nucleotidase family
JWY35_RS05185	COG3764	Sortase (surface protein transpeptidase)
JWY35_RS05190	COG0564	pseudouridine synthase activity
JWY35_RS05200	COG0517	IMP dehydrogenase activity
JWY35_RS05205	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JWY35_RS05210	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JWY35_RS05210	COG3153	acetyltransferase
JWY35_RS05215	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JWY35_RS05220	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
JWY35_RS05225	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JWY35_RS05230	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JWY35_RS05235	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JWY35_RS05240	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JWY35_RS05245	COG2203	Gaf domain
JWY35_RS05245	COG4585	Histidine kinase
JWY35_RS05250	COG2197	response regulator
JWY35_RS05255	COG0431	NADPH-dependent FMN reductase
JWY35_RS05270	COG1388	LysM domain
JWY35_RS05270	COG0791	NLP P60 protein
JWY35_RS05275	COG1959	2 iron, 2 sulfur cluster binding
JWY35_RS05280	COG0668	transmembrane transport
JWY35_RS05285	COG2719	SpoVR family
JWY35_RS05290	COG1785	Belongs to the alkaline phosphatase family
JWY35_RS05295	COG1388	LysM domain
JWY35_RS05295	COG0791	NLP P60 protein
JWY35_RS05300	COG0583	DNA-binding transcription factor activity
JWY35_RS05305	COG0372	Belongs to the citrate synthase family
JWY35_RS05310	COG1028	Short-chain dehydrogenase reductase Sdr
JWY35_RS05315	COG0531	amino acid
JWY35_RS05320	COG0733	neurotransmitter:sodium symporter activity
JWY35_RS05325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JWY35_RS05330	COG0456	acetyltransferase
JWY35_RS05345	COG1595	DNA-templated transcription, initiation
JWY35_RS05350	COG0667	Aldo Keto reductase
JWY35_RS05355	COG0204	Acyl-transferase
JWY35_RS05360	COG1253	flavin adenine dinucleotide binding
JWY35_RS05365	COG0789	Transcriptional regulator
JWY35_RS05375	COG1253	flavin adenine dinucleotide binding
JWY35_RS05380	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JWY35_RS05385	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JWY35_RS05390	COG0584	glycerophosphoryl diester phosphodiesterase
JWY35_RS05400	COG0668	transmembrane transport
JWY35_RS05405	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JWY35_RS05410	COG0726	polysaccharide deacetylase
JWY35_RS05415	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JWY35_RS05420	COG1757	Na H antiporter
JWY35_RS05425	COG0589	response to stress
JWY35_RS05435	COG1132	(ABC) transporter
JWY35_RS05440	COG1132	(ABC) transporter
JWY35_RS05445	COG0702	epimerase
JWY35_RS05470	COG0189	ligase activity
JWY35_RS05475	COG0189	ligase activity
JWY35_RS05480	COG4399	Belongs to the UPF0754 family
JWY35_RS05485	COG3679	Belongs to the UPF0342 family
JWY35_RS05495	COG0561	phosphatase activity
JWY35_RS05500	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JWY35_RS05505	COG0475	glutathione-regulated potassium exporter activity
JWY35_RS05510	COG0490	domain, Protein
JWY35_RS05520	COG1024	Enoyl-CoA hydratase
JWY35_RS05530	COG4152	abc transporter atp-binding protein
JWY35_RS05535	COG1668	transmembrane transport
JWY35_RS05540	COG0420	3'-5' exonuclease activity
JWY35_RS05545	COG4717	serine-type aminopeptidase activity
JWY35_RS05550	COG3481	metal-dependent phosphohydrolase, HD sub domain
JWY35_RS05560	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JWY35_RS05590	COG1846	Transcriptional regulator
JWY35_RS05595	COG4980	gas vesicle protein
JWY35_RS05610	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JWY35_RS05615	COG0537	adenosine 5'-monophosphoramidase activity
JWY35_RS05620	COG1131	(ABC) transporter
JWY35_RS05625	COG4473	ABC transporter
JWY35_RS05635	COG1473	amidohydrolase
JWY35_RS05640	COG3069	C4-dicarboxylate transmembrane transporter activity
JWY35_RS05650	COG2329	Antibiotic biosynthesis monooxygenase
JWY35_RS05655	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JWY35_RS05660	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JWY35_RS05665	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JWY35_RS05670	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JWY35_RS05675	COG1309	transcriptional regulator
JWY35_RS05680	COG1511	domain protein
JWY35_RS05685	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JWY35_RS05690	COG4377	Putative membrane peptidase family (DUF2324)
JWY35_RS05700	COG1363	Peptidase, m42
JWY35_RS05705	COG4405	Protein conserved in bacteria
JWY35_RS05710	COG1301	dicarboxylic acid transport
JWY35_RS05720	COG1234	tRNA 3'-trailer cleavage
JWY35_RS05725	COG0095	Lipoate-protein ligase
JWY35_RS05730	COG0702	epimerase
JWY35_RS05735	COG0318	PFAM AMP-dependent synthetase and ligase
JWY35_RS05745	COG0501	Belongs to the peptidase M48B family
JWY35_RS05755	COG0456	acetyltransferase
JWY35_RS05760	COG0604	alcohol dehydrogenase
JWY35_RS05765	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JWY35_RS05770	COG0406	alpha-ribazole phosphatase activity
JWY35_RS05775	COG0183	Belongs to the thiolase family
JWY35_RS05780	COG0318	PFAM AMP-dependent synthetase and ligase
JWY35_RS05785	COG1268	BioY protein
JWY35_RS05790	COG0840	transmembrane signaling receptor activity
JWY35_RS05800	COG1028	Short-chain dehydrogenase reductase Sdr
JWY35_RS05810	COG4903	ComK protein
JWY35_RS05815	COG1028	Short-chain dehydrogenase reductase Sdr
JWY35_RS05825	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JWY35_RS05840	COG0398	Pfam SNARE associated Golgi protein
JWY35_RS05845	COG0681	Belongs to the peptidase S26 family
JWY35_RS05850	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JWY35_RS05855	COG1846	Transcriptional regulator
JWY35_RS05865	COG0738	Major facilitator superfamily
JWY35_RS05870	COG0673	inositol 2-dehydrogenase activity
JWY35_RS05875	COG0561	phosphatase activity
JWY35_RS05880	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JWY35_RS05885	COG1609	Transcriptional regulator
JWY35_RS05890	COG3180	Ammonia monooxygenase
JWY35_RS05895	COG0477	Major facilitator Superfamily
JWY35_RS05895	COG2814	Major facilitator Superfamily
JWY35_RS05900	COG4533	DNA binding
JWY35_RS05920	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
JWY35_RS05925	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
JWY35_RS05930	COG1074	ATP-dependent DNA helicase activity
JWY35_RS05935	COG0420	3'-5' exonuclease activity
JWY35_RS05940	COG0419	ATPase involved in DNA repair
JWY35_RS05945	COG1403	HNH endonuclease
JWY35_RS05985	COG5337	Spore coat protein CotH
JWY35_RS05990	COG0179	Fumarylacetoacetate (FAA) hydrolase
JWY35_RS06000	COG1404	Belongs to the peptidase S8 family
JWY35_RS06010	COG0367	asparagine synthase
JWY35_RS06020	COG0534	Mate efflux family protein
JWY35_RS06025	COG2207	Transcriptional regulator
JWY35_RS06025	COG1917	Cupin 2, conserved barrel domain protein
JWY35_RS06030	COG1609	Transcriptional regulator
JWY35_RS06035	COG0673	inositol 2-dehydrogenase activity
JWY35_RS06040	COG2318	DinB family
JWY35_RS06045	COG1279	arginine transmembrane transporter activity
JWY35_RS06050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JWY35_RS06055	COG1357	PFAM Pentapeptide repeats (8 copies)
JWY35_RS06060	COG2267	carboxylic ester hydrolase activity
JWY35_RS06070	COG2153	protein acetylation
JWY35_RS06075	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JWY35_RS06075	COG0646	methionine synthase
JWY35_RS06080	COG1666	GTP binding
JWY35_RS06095	COG1307	EDD domain protein, DegV family
JWY35_RS06100	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JWY35_RS06120	COG0561	phosphatase activity
JWY35_RS06125	COG1073	alpha beta
JWY35_RS06130	COG2151	metal-sulfur cluster biosynthetic enzyme
JWY35_RS06140	COG0277	FAD linked oxidase domain protein
JWY35_RS06150	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JWY35_RS06155	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JWY35_RS06165	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JWY35_RS06170	COG0505	Belongs to the CarA family
JWY35_RS06175	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JWY35_RS06180	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JWY35_RS06200	COG2267	carboxylic ester hydrolase activity
JWY35_RS06210	COG1744	ABC transporter substrate-binding protein PnrA-like
JWY35_RS06225	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JWY35_RS06230	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JWY35_RS06235	COG5504	Zn-dependent protease
JWY35_RS06240	COG0444	Belongs to the ABC transporter superfamily
JWY35_RS06245	COG4608	Belongs to the ABC transporter superfamily
JWY35_RS06255	COG0601	transmembrane transport
JWY35_RS06260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JWY35_RS06270	COG0180	Tryptophanyl-tRNA synthetase
JWY35_RS06275	COG4166	transmembrane transport
JWY35_RS06280	COG0601	transmembrane transport
JWY35_RS06285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JWY35_RS06290	COG0444	Belongs to the ABC transporter superfamily
JWY35_RS06295	COG4608	Belongs to the ABC transporter superfamily
JWY35_RS06300	COG2814	Major facilitator Superfamily
JWY35_RS06305	COG0456	acetyltransferase
JWY35_RS06310	COG1393	Belongs to the ArsC family
JWY35_RS06315	COG0861	Integral membrane protein TerC family
JWY35_RS06325	COG4862	establishment of competence for transformation
JWY35_RS06335	COG4469	Competence protein
JWY35_RS06340	COG1164	Oligoendopeptidase f
JWY35_RS06350	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JWY35_RS06355	COG2346	COG2346, Truncated hemoglobins
JWY35_RS06360	COG0741	lytic transglycosylase activity
JWY35_RS06365	COG4116	CYTH
JWY35_RS06375	COG2357	RelA SpoT domain protein
JWY35_RS06380	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JWY35_RS06385	COG0564	pseudouridine synthase activity
JWY35_RS06390	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JWY35_RS06395	COG0569	domain protein
JWY35_RS06395	COG0475	glutathione-regulated potassium exporter activity
JWY35_RS06400	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JWY35_RS06405	COG0352	thiamine-phosphate diphosphorylase activity
JWY35_RS06410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JWY35_RS06415	COG2104	thiamine diphosphate biosynthetic process
JWY35_RS06420	COG2022	thiamine diphosphate biosynthetic process
JWY35_RS06425	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JWY35_RS06430	COG0351	phosphomethylpyrimidine kinase
JWY35_RS06435	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JWY35_RS06490	COG0210	DNA helicase
JWY35_RS06500	COG2153	protein acetylation
JWY35_RS06505	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JWY35_RS06510	COG2382	esterase
JWY35_RS06515	COG0626	cystathionine gamma-synthase activity
JWY35_RS06520	COG0626	cystathionine gamma-synthase activity
JWY35_RS06525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JWY35_RS06530	COG5505	Protein of unknown function (DUF819)
JWY35_RS06570	COG1396	sequence-specific DNA binding
JWY35_RS06655	COG0457	Tetratricopeptide repeat
JWY35_RS06660	COG5444	nuclease activity
JWY35_RS06670	COG3328	transposase activity
JWY35_RS06730	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
JWY35_RS06740	COG3711	transcriptional antiterminator
JWY35_RS06740	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JWY35_RS06745	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JWY35_RS06745	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JWY35_RS06745	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JWY35_RS06750	COG1482	cell wall glycoprotein biosynthetic process
JWY35_RS06765	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JWY35_RS06775	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JWY35_RS06790	COG0109	protoheme IX farnesyltransferase activity
JWY35_RS06800	COG0726	polysaccharide deacetylase
JWY35_RS06815	COG5504	Zn-dependent protease
JWY35_RS06820	COG2205	protein histidine kinase activity
JWY35_RS06835	COG2427	Protein of unknown function (DUF1641)
JWY35_RS06845	COG1051	belongs to the nudix hydrolase family
JWY35_RS06855	COG2124	cytochrome p450
JWY35_RS06860	COG1819	glycosyl
JWY35_RS06870	COG1587	Uroporphyrinogen-III synthase
JWY35_RS06875	COG0390	transport system, permease component
JWY35_RS06880	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JWY35_RS06885	COG0697	spore germination
JWY35_RS06900	COG1252	NADH dehydrogenase
JWY35_RS06905	COG1904	glucuronate isomerase
JWY35_RS06910	COG2211	Major facilitator Superfamily
JWY35_RS06915	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
JWY35_RS06920	COG1063	alcohol dehydrogenase
JWY35_RS06925	COG1312	Catalyzes the dehydration of D-mannonate
JWY35_RS06930	COG1028	Short-chain dehydrogenase reductase Sdr
JWY35_RS06935	COG2271	Major facilitator Superfamily
JWY35_RS06940	COG1609	Transcriptional regulator
JWY35_RS06945	COG0246	Mannitol dehydrogenase
JWY35_RS06950	COG2721	sulfolactate sulfo-lyase activity
JWY35_RS06955	COG0730	response to heat
JWY35_RS06960	COG2318	DinB family
JWY35_RS06980	COG0457	Tetratricopeptide repeat
JWY35_RS06995	COG1388	LysM domain
JWY35_RS06995	COG3409	Peptidoglycan-binding domain 1 protein
JWY35_RS06995	COG5632	N-Acetylmuramoyl-L-alanine amidase
JWY35_RS07005	COG4195	phage-related replication protein
JWY35_RS07010	COG3546	catalase activity
JWY35_RS07015	COG2856	Zn peptidase
JWY35_RS07020	COG1396	sequence-specific DNA binding
JWY35_RS07030	COG1522	sequence-specific DNA binding
JWY35_RS07035	COG1484	DNA-dependent DNA replication
JWY35_RS07055	COG1595	DNA-templated transcription, initiation
JWY35_RS07060	COG5484	DNA packaging
JWY35_RS07060	COG3728	DNA packaging
JWY35_RS07065	COG1783	phage Terminase large subunit
JWY35_RS07070	COG5518	Phage portal protein
JWY35_RS07075	COG0338	D12 class N6 adenine-specific DNA methyltransferase
JWY35_RS07080	COG4653	Phage capsid family
JWY35_RS07130	COG3953	SLT domain
JWY35_RS07130	COG5412	phage tail tape measure protein
JWY35_RS07130	COG3953	SLT domain
JWY35_RS07130	COG3953	SLT domain
JWY35_RS07130	COG5412	phage tail tape measure protein
JWY35_RS07130	COG5412	phage tail tape measure protein
JWY35_RS07135	COG1652	LysM domain
JWY35_RS07140	COG4193	domain, Protein
JWY35_RS07150	COG3628	GPW Gp25 family protein
JWY35_RS07155	COG3299	homolog of phage Mu protein gp47
JWY35_RS07160	COG3778	Protein conserved in bacteria
JWY35_RS07200	COG3409	Peptidoglycan-binding domain 1 protein
JWY35_RS07200	COG5632	N-Acetylmuramoyl-L-alanine amidase
JWY35_RS07220	COG0306	phosphate transporter
JWY35_RS07225	COG1392	Phosphate transport regulator
JWY35_RS07230	COG0531	amino acid
JWY35_RS07235	COG0346	lactoylglutathione lyase activity
JWY35_RS07245	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JWY35_RS07250	COG0463	Glycosyl transferase, family 2
JWY35_RS07255	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JWY35_RS07260	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JWY35_RS07265	COG2362	D-Aminopeptidase
JWY35_RS07270	COG0601	transmembrane transport
JWY35_RS07275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JWY35_RS07280	COG0444	Belongs to the ABC transporter superfamily
JWY35_RS07285	COG4166	transmembrane transport
JWY35_RS07290	COG1619	proteins homologs of microcin C7 resistance protein MccF
JWY35_RS07295	COG4948	Mandelate Racemase Muconate Lactonizing
JWY35_RS07300	COG0791	NLP P60 protein
JWY35_RS07305	COG4608	Belongs to the ABC transporter superfamily
JWY35_RS07310	COG2706	6-phosphogluconolactonase activity
JWY35_RS07320	COG1607	acyl-coa hydrolase
JWY35_RS07325	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JWY35_RS07325	COG1017	nitric oxide dioxygenase activity
JWY35_RS07335	COG2323	membrane
JWY35_RS07340	COG2318	DinB family
JWY35_RS07345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JWY35_RS07350	COG2076	Multidrug Resistance protein
JWY35_RS07355	COG2076	Multidrug Resistance protein
JWY35_RS07360	COG0788	formyltetrahydrofolate deformylase activity
JWY35_RS07365	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JWY35_RS07370	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JWY35_RS07375	COG1764	response to oxidative stress
JWY35_RS07380	COG1846	Transcriptional regulator
JWY35_RS07385	COG1764	response to oxidative stress
JWY35_RS07395	COG0590	tRNA wobble adenosine to inosine editing
JWY35_RS07400	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JWY35_RS07405	COG1404	Belongs to the peptidase S8 family
JWY35_RS07410	COG1366	Belongs to the anti-sigma-factor antagonist family
JWY35_RS07415	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JWY35_RS07420	COG1122	ATPase activity
JWY35_RS07425	COG4721	ABC-type cobalt transport system, permease component
JWY35_RS07435	COG0745	RESPONSE REGULATOR receiver
JWY35_RS07440	COG5002	protein histidine kinase activity
JWY35_RS07440	COG3850	Histidine kinase
JWY35_RS07445	COG3212	peptidase
JWY35_RS07450	COG3212	peptidase
JWY35_RS07460	COG2239	Acts as a magnesium transporter
JWY35_RS07465	COG0789	Transcriptional regulator
JWY35_RS07480	COG1846	Transcriptional regulator
JWY35_RS07485	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JWY35_RS07490	COG0726	polysaccharide deacetylase
JWY35_RS07495	COG1408	metallophosphoesterase
JWY35_RS07505	COG0463	Glycosyl transferase, family 2
JWY35_RS07510	COG3285	dna ligase
JWY35_RS07510	COG1793	dna ligase
JWY35_RS07515	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
JWY35_RS07520	COG3300	MHYT domain
JWY35_RS07520	COG5001	Diguanylate cyclase
JWY35_RS07525	COG0586	Pfam SNARE associated Golgi protein
JWY35_RS07530	COG0861	Integral membrane protein TerC family
JWY35_RS07535	COG1191	sigma factor activity
JWY35_RS07555	COG0501	Belongs to the peptidase M48B family
JWY35_RS07560	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JWY35_RS07585	COG3594	Acyltransferase
JWY35_RS07590	COG5002	protein histidine kinase activity
JWY35_RS07595	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JWY35_RS07605	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
JWY35_RS07610	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
JWY35_RS07615	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JWY35_RS07620	COG0436	Aminotransferase
JWY35_RS07625	COG1850	ribulose-bisphosphate carboxylase activity
JWY35_RS07630	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
JWY35_RS07635	COG0235	Class ii aldolase
JWY35_RS07640	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
JWY35_RS07645	COG3339	Conserved Protein
JWY35_RS07660	COG3852	Histidine kinase
JWY35_RS07665	COG1846	Transcriptional regulator
JWY35_RS07670	COG1360	Flagellar Motor Protein
JWY35_RS07675	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JWY35_RS07680	COG0542	response to heat
JWY35_RS07685	COG3949	Membrane
JWY35_RS07690	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JWY35_RS07695	COG0720	synthase
JWY35_RS07700	COG0602	queuosine metabolic process
JWY35_RS07705	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JWY35_RS07715	COG4873	Protein conserved in bacteria
JWY35_RS07725	COG3773	Cell wall hydrolase
JWY35_RS07730	COG2244	polysaccharide biosynthetic process
JWY35_RS07735	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JWY35_RS07740	COG2217	Heavy metal translocating P-type atpase
JWY35_RS07750	COG0006	proline dipeptidase activity
JWY35_RS07755	COG1609	Transcriptional regulator
JWY35_RS07765	COG1263	PTS System
JWY35_RS07765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JWY35_RS07765	COG2190	(PTS) system
JWY35_RS07770	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JWY35_RS07775	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JWY35_RS07785	COG1533	DNA photolyase activity
JWY35_RS07790	COG0456	acetyltransferase
JWY35_RS07795	COG0840	transmembrane signaling receptor activity
JWY35_RS07800	COG2084	Dehydrogenase
JWY35_RS07810	COG3328	transposase activity
JWY35_RS07820	COG0768	penicillin binding
JWY35_RS07825	COG4191	Histidine kinase
JWY35_RS07830	COG0436	Aminotransferase
JWY35_RS07840	COG0784	Response regulator, receiver
JWY35_RS07840	COG0835	chemotaxis
JWY35_RS07850	COG2814	Major facilitator Superfamily
JWY35_RS07855	COG1376	ErfK ybiS ycfS ynhG family protein
JWY35_RS07860	COG1408	metallophosphoesterase
JWY35_RS07865	COG1028	Short-chain dehydrogenase reductase Sdr
JWY35_RS07870	COG2200	EAL domain
JWY35_RS07875	COG4703	Protein of unknown function (DUF1797)
JWY35_RS07880	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
JWY35_RS07890	COG0517	IMP dehydrogenase activity
JWY35_RS07895	COG0583	DNA-binding transcription factor activity
JWY35_RS07900	COG0716	FMN binding
JWY35_RS07910	COG0716	FMN binding
JWY35_RS07915	COG2171	N-acyltransferase activity
JWY35_RS07920	COG1473	amidohydrolase
JWY35_RS07930	COG0668	transmembrane transport
JWY35_RS07935	COG0450	alkyl hydroperoxide reductase
JWY35_RS07940	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JWY35_RS07960	COG0746	molybdenum cofactor guanylyltransferase activity
JWY35_RS07965	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JWY35_RS07970	COG0303	'Molybdopterin
JWY35_RS07975	COG1763	Mo-molybdopterin cofactor biosynthetic process
JWY35_RS07980	COG0314	molybdopterin synthase activity
JWY35_RS07985	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
JWY35_RS07995	COG1132	(ABC) transporter
JWY35_RS08005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JWY35_RS08010	COG1136	(ABC) transporter
JWY35_RS08015	COG0577	efflux transmembrane transporter activity
JWY35_RS08020	COG1349	DNA-binding transcription factor activity
JWY35_RS08025	COG1105	Belongs to the carbohydrate kinase PfkB family
JWY35_RS08030	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JWY35_RS08030	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JWY35_RS08030	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JWY35_RS08035	COG0681	Belongs to the peptidase S26 family
JWY35_RS08045	COG0488	(ABC) transporter
JWY35_RS08050	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JWY35_RS08055	COG2309	aminopeptidase activity
JWY35_RS08065	COG1077	Cell shape determining protein MreB Mrl
JWY35_RS08070	COG2002	toxin-antitoxin pair type II binding
JWY35_RS08075	COG3852	Histidine kinase
JWY35_RS08080	COG2105	PFAM AIG2 family protein
JWY35_RS08080	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
JWY35_RS08085	COG0569	domain protein
JWY35_RS08090	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JWY35_RS08095	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JWY35_RS08100	COG5503	Protein of unknown function (DUF1447)
JWY35_RS08105	COG0561	phosphatase activity
JWY35_RS08110	COG0242	peptide deformylase activity
JWY35_RS08125	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JWY35_RS08130	COG0022	dehydrogenase e1 component
JWY35_RS08135	COG0508	dehydrogenase complex catalyzes the overall conversion of
JWY35_RS08140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JWY35_RS08145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JWY35_RS08155	COG1982	Orn Lys Arg decarboxylase major
JWY35_RS08160	COG4476	Belongs to the UPF0223 family
JWY35_RS08165	COG4493	Belongs to the UPF0637 family
JWY35_RS08175	COG0483	inositol monophosphate 1-phosphatase activity
JWY35_RS08190	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JWY35_RS08230	COG1217	gtp-binding protein TYPA
JWY35_RS08240	COG4896	Protein conserved in bacteria
JWY35_RS08250	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JWY35_RS08255	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JWY35_RS08260	COG2066	Belongs to the glutaminase family
JWY35_RS08265	COG4838	Belongs to the UPF0358 family
JWY35_RS08270	COG0772	Belongs to the SEDS family
JWY35_RS08275	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JWY35_RS08280	COG1612	heme a metabolic process
JWY35_RS08285	COG0109	protoheme IX farnesyltransferase activity
JWY35_RS08290	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JWY35_RS08290	COG2010	Cytochrome c
JWY35_RS08295	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JWY35_RS08300	COG1845	cytochrome c oxidase, subunit III
JWY35_RS08305	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JWY35_RS08310	COG3336	cytochrome c oxidase
JWY35_RS08320	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
JWY35_RS08325	COG2340	Cysteine-rich secretory protein family
JWY35_RS08340	COG3679	Belongs to the UPF0342 family
JWY35_RS08345	COG4471	UPF0298 protein
JWY35_RS08350	COG0742	ribosomal rna small subunit methyltransferase
JWY35_RS08355	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JWY35_RS08360	COG3314	Sporulation integral membrane protein YlbJ
JWY35_RS08365	COG1752	Esterase of the alpha-beta hydrolase superfamily
JWY35_RS08370	COG3480	Lon protease (S16) C-terminal proteolytic domain
JWY35_RS08375	COG1323	Belongs to the UPF0348 family
JWY35_RS08385	COG1399	metal-binding, possibly nucleic acid-binding protein
JWY35_RS08400	COG0454	-acetyltransferase
JWY35_RS08405	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JWY35_RS08410	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
JWY35_RS08415	COG2001	Belongs to the MraZ family
JWY35_RS08420	COG0275	rRNA processing
JWY35_RS08425	COG4839	cell division protein FtsL
JWY35_RS08430	COG0768	penicillin binding
JWY35_RS08435	COG0768	penicillin binding
JWY35_RS08440	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JWY35_RS08445	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JWY35_RS08450	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JWY35_RS08455	COG0772	Belongs to the SEDS family
JWY35_RS08460	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JWY35_RS08465	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JWY35_RS08470	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JWY35_RS08475	COG3879	Bacterial protein of unknown function (DUF881)
JWY35_RS08480	COG3879	Bacterial protein of unknown function (DUF881)
JWY35_RS08485	COG3856	small basic protein
JWY35_RS08490	COG0849	cell division
JWY35_RS08495	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JWY35_RS08500	COG1404	Belongs to the peptidase S8 family
JWY35_RS08500	COG4412	M6 family metalloprotease domain protein
JWY35_RS08510	COG1191	sigma factor activity
JWY35_RS08515	COG1191	sigma factor activity
JWY35_RS08520	COG1119	ATPase activity
JWY35_RS08525	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JWY35_RS08530	COG1873	PFAM PRC-barrel domain
JWY35_RS08535	COG1496	oxidoreductase activity
JWY35_RS08540	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JWY35_RS08545	COG1799	cell septum assembly
JWY35_RS08550	COG0762	integral membrane protein
JWY35_RS08555	COG2302	S4 RNA-binding domain
JWY35_RS08560	COG3599	regulation of cell shape
JWY35_RS08565	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JWY35_RS08570	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JWY35_RS08575	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JWY35_RS08580	COG0564	pseudouridine synthase activity
JWY35_RS08585	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JWY35_RS08590	COG2233	PERMEase
JWY35_RS08595	COG0540	Belongs to the ATCase OTCase family
JWY35_RS08600	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JWY35_RS08605	COG0505	Belongs to the CarA family
JWY35_RS08610	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JWY35_RS08615	COG0543	2 iron, 2 sulfur cluster binding
JWY35_RS08620	COG0167	dihydroorotate dehydrogenase activity
JWY35_RS08625	COG0284	orotidine-5'-phosphate decarboxylase activity
JWY35_RS08630	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JWY35_RS08635	COG0175	sulfate reduction
JWY35_RS08640	COG0306	phosphate transporter
JWY35_RS08645	COG2046	Belongs to the sulfate adenylyltransferase family
JWY35_RS08650	COG0529	Catalyzes the synthesis of activated sulfate
JWY35_RS08655	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JWY35_RS08660	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
JWY35_RS08665	COG1648	precorrin-2 dehydrogenase activity
JWY35_RS08675	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JWY35_RS08680	COG1561	YicC-like family, N-terminal region
JWY35_RS08690	COG0194	GDP metabolic process
JWY35_RS08695	COG1758	RNA polymerase activity
JWY35_RS08700	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JWY35_RS08705	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JWY35_RS08710	COG0242	peptide deformylase activity
JWY35_RS08715	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JWY35_RS08720	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JWY35_RS08720	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JWY35_RS08725	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JWY35_RS08730	COG0631	protein serine/threonine phosphatase activity
JWY35_RS08735	COG2815	serine threonine protein kinase
JWY35_RS08735	COG0515	serine threonine protein kinase
JWY35_RS08740	COG1162	GTPase activity
JWY35_RS08745	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JWY35_RS08750	COG1564	THIamine pyrophosphokinase
JWY35_RS08760	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JWY35_RS08765	COG1302	Protein conserved in bacteria
JWY35_RS08770	COG1461	Dihydroxyacetone kinase
JWY35_RS08775	COG1760	l-serine dehydratase
JWY35_RS08780	COG1760	l-serine dehydratase
JWY35_RS08785	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JWY35_RS08790	COG1349	DNA-binding transcription factor activity
JWY35_RS08790	COG2050	protein possibly involved in aromatic compounds catabolism
JWY35_RS08795	COG0416	fatty acid biosynthetic process
JWY35_RS08800	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JWY35_RS08805	COG1028	Short-chain dehydrogenase reductase Sdr
JWY35_RS08815	COG0571	ribonuclease III activity
JWY35_RS08820	COG1196	nuclear chromosome segregation
JWY35_RS08825	COG0552	protein localization to endoplasmic reticulum
JWY35_RS08835	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JWY35_RS08840	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JWY35_RS08845	COG0228	four-way junction DNA binding
JWY35_RS08850	COG1837	Belongs to the UPF0109 family
JWY35_RS08860	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JWY35_RS08865	COG0336	Belongs to the RNA methyltransferase TrmD family
JWY35_RS08870	COG0335	large ribosomal subunit rRNA binding
JWY35_RS08875	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JWY35_RS08880	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JWY35_RS08890	COG2257	FlhB HrpN YscU SpaS Family
JWY35_RS08895	COG0045	succinate-CoA ligase (ADP-forming) activity
JWY35_RS08900	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JWY35_RS08905	COG0758	DNA mediated transformation
JWY35_RS08910	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JWY35_RS08915	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JWY35_RS08920	COG4974	Belongs to the 'phage' integrase family
JWY35_RS08925	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JWY35_RS08930	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JWY35_RS08935	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JWY35_RS08940	COG1815	bacterial-type flagellum-dependent cell motility
JWY35_RS08945	COG1558	bacterial-type flagellum-dependent cell motility
JWY35_RS08950	COG1677	Flagellar hook-basal body complex protein FliE
JWY35_RS08960	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JWY35_RS08965	COG1317	bacterial-type flagellum organization
JWY35_RS08970	COG1157	protein secretion by the type III secretion system
JWY35_RS08975	COG2882	bacterial-type flagellum organization
JWY35_RS08980	COG3334	PFAM MgtE intracellular
JWY35_RS08985	COG3144	bacterial-type flagellum assembly
JWY35_RS08990	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
JWY35_RS08995	COG4786	Flagellar basal body rod
JWY35_RS09000	COG1582	Flagellar protein (FlbD)
JWY35_RS09005	COG1580	Controls the rotational direction of flagella during chemotaxis
JWY35_RS09010	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JWY35_RS09015	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JWY35_RS09015	COG1776	CheC inhibitor of MCP methylation
JWY35_RS09020	COG2201	protein-glutamate methylesterase activity
JWY35_RS09025	COG3190	flagellar
JWY35_RS09030	COG1338	Plays a role in the flagellum-specific transport system
JWY35_RS09035	COG1987	bacterial-type flagellum assembly
JWY35_RS09045	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JWY35_RS09050	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JWY35_RS09055	COG1419	protein localization to endoplasmic reticulum
JWY35_RS09060	COG0455	bacterial-type flagellum organization
JWY35_RS09065	COG2201	protein-glutamate methylesterase activity
JWY35_RS09070	COG0643	Histidine kinase
JWY35_RS09070	COG2198	Histidine kinase
JWY35_RS09075	COG0835	chemotaxis
JWY35_RS09085	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
JWY35_RS09090	COG1191	sigma factor activity
JWY35_RS09100	COG0052	Belongs to the universal ribosomal protein uS2 family
JWY35_RS09105	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JWY35_RS09110	COG0528	UMP kinase activity
JWY35_RS09115	COG0233	cytoplasmic translational termination
JWY35_RS09120	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JWY35_RS09125	COG4589	Belongs to the CDS family
JWY35_RS09130	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JWY35_RS09135	COG0750	zinc metalloprotease
JWY35_RS09140	COG0442	prolyl-tRNA aminoacylation
JWY35_RS09145	COG2176	DNA-directed DNA polymerase activity
JWY35_RS09150	COG0779	Required for maturation of 30S ribosomal subunits
JWY35_RS09155	COG0195	Participates in both transcription termination and antitermination
JWY35_RS09160	COG2740	Nucleic-acid-binding protein implicated in transcription termination
JWY35_RS09165	COG1358	cellular component organization or biogenesis
JWY35_RS09170	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JWY35_RS09175	COG1550	Protein conserved in bacteria
JWY35_RS09180	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JWY35_RS09185	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JWY35_RS09190	COG0196	riboflavin kinase activity
JWY35_RS09195	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JWY35_RS09200	COG1185	polyribonucleotide nucleotidyltransferase activity
JWY35_RS09205	COG0726	polysaccharide deacetylase
JWY35_RS09210	COG0612	Peptidase, M16
JWY35_RS09215	COG1873	PFAM PRC-barrel domain
JWY35_RS09220	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JWY35_RS09225	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JWY35_RS09230	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JWY35_RS09235	COG0527	aspartate kinase activity
JWY35_RS09240	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JWY35_RS09245	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JWY35_RS09250	COG0740	serine-type endopeptidase activity
JWY35_RS09260	COG1674	ftsk spoiiie
JWY35_RS09260	COG4980	gas vesicle protein
JWY35_RS09265	COG2188	Transcriptional regulator
JWY35_RS09270	COG2814	Major facilitator Superfamily
JWY35_RS09275	COG0612	Peptidase, M16
JWY35_RS09280	COG0612	Peptidase, M16
JWY35_RS09285	COG0300	oxidoreductase activity
JWY35_RS09300	COG1426	Protein conserved in bacteria
JWY35_RS09305	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JWY35_RS09310	COG1546	Belongs to the CinA family
JWY35_RS09310	COG1058	Belongs to the CinA family
JWY35_RS09315	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JWY35_RS09320	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JWY35_RS09325	COG1418	mRNA catabolic process
JWY35_RS09330	COG1692	metallophosphoesterase
JWY35_RS09335	COG2359	stage V sporulation protein S
JWY35_RS09340	COG1063	alcohol dehydrogenase
JWY35_RS09345	COG0156	8-amino-7-oxononanoate synthase activity
JWY35_RS09350	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JWY35_RS09355	COG4550	Control of competence regulator ComK, YlbF/YmcA
JWY35_RS09365	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JWY35_RS09370	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JWY35_RS09475	COG3226	Transcriptional regulator
JWY35_RS09485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JWY35_RS09490	COG1404	Belongs to the peptidase S8 family
JWY35_RS09500	COG4195	phage-related replication protein
JWY35_RS09505	COG1764	response to oxidative stress
JWY35_RS09510	COG2076	Multidrug Resistance protein
JWY35_RS09515	COG2076	Multidrug Resistance protein
JWY35_RS09530	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JWY35_RS09535	COG1923	regulation of RNA biosynthetic process
JWY35_RS09550	COG1780	Probably involved in ribonucleotide reductase function
JWY35_RS09555	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JWY35_RS09560	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JWY35_RS09565	COG4112	unkown
JWY35_RS09570	COG0860	N-Acetylmuramoyl-L-alanine amidase
JWY35_RS09575	COG0464	growth
JWY35_RS09580	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JWY35_RS09585	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
JWY35_RS09590	COG0789	Transcriptional regulator
JWY35_RS09595	COG0174	glutamine synthetase
JWY35_RS09600	COG4974	Belongs to the 'phage' integrase family
JWY35_RS09620	COG3645	SOS response
JWY35_RS09620	COG3646	Phage regulatory protein
JWY35_RS09765	COG3953	SLT domain
JWY35_RS09765	COG5412	phage tail tape measure protein
JWY35_RS09810	COG5632	N-Acetylmuramoyl-L-alanine amidase
JWY35_RS09810	COG3409	Peptidoglycan-binding domain 1 protein
JWY35_RS09810	COG1388	LysM domain
JWY35_RS09820	COG5444	nuclease activity
JWY35_RS09855	COG4282	regulation of fungal-type cell wall biogenesis
JWY35_RS09890	COG3655	Transcriptional regulator
JWY35_RS09915	COG0135	phosphoribosylanthranilate isomerase activity
JWY35_RS09925	COG2211	Major facilitator Superfamily
JWY35_RS09940	COG3507	Belongs to the glycosyl hydrolase 43 family
JWY35_RS09945	COG1940	carbohydrate kinase activity
JWY35_RS09950	COG2115	Belongs to the xylose isomerase family
JWY35_RS09955	COG1070	Carbohydrate kinase
JWY35_RS09965	COG3328	transposase activity
JWY35_RS09970	COG1525	nuclease
JWY35_RS09975	COG2814	Major facilitator Superfamily
JWY35_RS09980	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JWY35_RS09995	COG0756	dUTP diphosphatase activity
JWY35_RS10035	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JWY35_RS10055	COG3832	glyoxalase III activity
JWY35_RS10095	COG4195	phage-related replication protein
JWY35_RS10105	COG0346	lactoylglutathione lyase activity
JWY35_RS10115	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JWY35_RS10120	COG1388	LysM domain
JWY35_RS10125	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JWY35_RS10130	COG4224	UPF0291 protein
JWY35_RS10135	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JWY35_RS10145	COG3763	UPF0154 protein
JWY35_RS10155	COG0785	Cytochrome C biogenesis protein
JWY35_RS10160	COG2201	protein-glutamate methylesterase activity
JWY35_RS10165	COG4846	Membrane protein involved in cytochrome C biogenesis
JWY35_RS10175	COG0071	Belongs to the small heat shock protein (HSP20) family
JWY35_RS10190	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JWY35_RS10195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JWY35_RS10215	COG0824	Thioesterase
JWY35_RS10225	COG4841	protein insertion into membrane
JWY35_RS10230	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JWY35_RS10235	COG1832	CoA-binding protein
JWY35_RS10240	COG0187	DNA topoisomerase II activity
JWY35_RS10245	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JWY35_RS10255	COG1115	amino acid carrier protein
JWY35_RS10260	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JWY35_RS10270	COG5520	Belongs to the glycosyl hydrolase 30 family
JWY35_RS10280	COG2246	polysaccharide biosynthetic process
JWY35_RS10285	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JWY35_RS10290	COG0586	Pfam SNARE associated Golgi protein
JWY35_RS10295	COG2404	hydrolase activity, acting on ester bonds
JWY35_RS10300	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JWY35_RS10305	COG1024	Enoyl-CoA hydratase
JWY35_RS10310	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JWY35_RS10315	COG0511	ligase activity, forming carbon-carbon bonds
JWY35_RS10320	COG0439	Biotin carboxylase
JWY35_RS10325	COG0318	PFAM AMP-dependent synthetase and ligase
JWY35_RS10330	COG1960	acyl-CoA dehydrogenase activity
JWY35_RS10345	COG1649	PFAM Uncharacterised BCR, COG1649
JWY35_RS10360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JWY35_RS10365	COG2027	D-alanyl-D-alanine carboxypeptidase
JWY35_RS10370	COG2017	converts alpha-aldose to the beta-anomer
JWY35_RS10375	COG0534	Mate efflux family protein
JWY35_RS10395	COG0582	viral genome integration into host DNA
JWY35_RS10400	COG0166	Belongs to the GPI family
JWY35_RS10405	COG0405	Gamma-glutamyltransferase
JWY35_RS10410	COG0583	DNA-binding transcription factor activity
JWY35_RS10415	COG0604	alcohol dehydrogenase
JWY35_RS10420	COG0493	'glutamate synthase
JWY35_RS10425	COG0067	glutamate synthase
JWY35_RS10425	COG0069	glutamate synthase activity
JWY35_RS10425	COG0070	glutamate synthase
JWY35_RS10430	COG0583	DNA-binding transcription factor activity
JWY35_RS10460	COG0300	oxidoreductase activity
JWY35_RS10465	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
JWY35_RS10475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JWY35_RS10490	COG1131	(ABC) transporter
JWY35_RS10500	COG2814	Major facilitator Superfamily
JWY35_RS10505	COG3328	transposase activity
JWY35_RS10535	COG3328	transposase activity
JWY35_RS10590	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JWY35_RS10595	COG2226	methyltransferase
JWY35_RS10600	COG2211	Major facilitator Superfamily
JWY35_RS10605	COG3328	transposase activity
JWY35_RS10635	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JWY35_RS10655	COG5444	nuclease activity
JWY35_RS10660	COG4282	regulation of fungal-type cell wall biogenesis
JWY35_RS10665	COG1231	oxidoreductase activity
JWY35_RS10670	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JWY35_RS10675	COG2207	Transcriptional regulator
JWY35_RS10675	COG0662	Cupin 2, conserved barrel domain protein
JWY35_RS10680	COG0456	acetyltransferase
JWY35_RS10685	COG1309	transcriptional regulator
JWY35_RS10690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JWY35_RS10695	COG3708	Transcriptional regulator
JWY35_RS10700	COG2378	regulation of single-species biofilm formation
JWY35_RS10710	COG0640	Transcriptional regulator
JWY35_RS10715	COG0741	lytic transglycosylase activity
JWY35_RS10720	COG2322	membrane
JWY35_RS10735	COG1619	proteins homologs of microcin C7 resistance protein MccF
JWY35_RS10740	COG3239	Fatty acid desaturase
JWY35_RS10745	COG4585	Histidine kinase
JWY35_RS10750	COG2197	response regulator
JWY35_RS10755	COG1388	LysM domain
JWY35_RS10755	COG3584	3D domain protein
JWY35_RS10760	COG0514	ATP-dependent DNA helicase (RecQ)
JWY35_RS10770	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JWY35_RS10775	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JWY35_RS10790	COG0071	Belongs to the small heat shock protein (HSP20) family
JWY35_RS10815	COG1012	belongs to the aldehyde dehydrogenase family
JWY35_RS10820	COG1657	PFAM Prenyltransferase squalene oxidase
JWY35_RS10825	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JWY35_RS10830	COG0733	neurotransmitter:sodium symporter activity
JWY35_RS10835	COG0385	Bile acid
JWY35_RS10840	COG0508	dehydrogenase complex catalyzes the overall conversion of
JWY35_RS10845	COG0567	Dehydrogenase, E1 component
JWY35_RS10850	COG4548	von Willebrand factor, type A
JWY35_RS10855	COG0714	Associated with various cellular activities
JWY35_RS10860	COG2032	superoxide dismutase activity
JWY35_RS10865	COG1388	LysM domain
JWY35_RS10865	COG0791	NLP P60 protein
JWY35_RS10870	COG1819	glycosyl
JWY35_RS10875	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JWY35_RS10880	COG0534	Mate efflux family protein
JWY35_RS10885	COG1366	Belongs to the anti-sigma-factor antagonist family
JWY35_RS10890	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JWY35_RS10895	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JWY35_RS10905	COG2962	Rard protein
JWY35_RS10920	COG2610	gluconate transmembrane transporter activity
JWY35_RS10925	COG2610	gluconate transmembrane transporter activity
JWY35_RS10930	COG1942	4-Oxalocrotonate Tautomerase
JWY35_RS10935	COG1733	regulation of RNA biosynthetic process
JWY35_RS10940	COG0778	Nitroreductase
JWY35_RS10950	COG0400	carboxylic ester hydrolase activity
JWY35_RS10965	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JWY35_RS10970	COG3409	Peptidoglycan-binding domain 1 protein
JWY35_RS10970	COG0793	Belongs to the peptidase S41A family
JWY35_RS10975	COG2226	methyltransferase
JWY35_RS10985	COG1876	peptidase activity
JWY35_RS10990	COG0813	purine-nucleoside phosphorylase activity
JWY35_RS11005	COG0671	phosphoesterase, PA-phosphatase related
JWY35_RS11025	COG4479	Belongs to the UPF0346 family
JWY35_RS11035	COG1509	lysine 2,3-aminomutase activity
JWY35_RS11040	COG0456	acetyltransferase
JWY35_RS11045	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JWY35_RS11050	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JWY35_RS11055	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JWY35_RS11060	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JWY35_RS11075	COG0456	acetyltransferase
JWY35_RS11080	COG0463	Glycosyl transferase, family 2
JWY35_RS11095	COG4641	Protein conserved in bacteria
JWY35_RS11100	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
JWY35_RS11105	COG1086	Polysaccharide biosynthesis protein
JWY35_RS11110	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JWY35_RS11115	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JWY35_RS11120	COG1846	Transcriptional regulator
JWY35_RS11125	COG0534	Mate efflux family protein
JWY35_RS11135	COG4698	Protein conserved in bacteria
JWY35_RS11140	COG2755	lipolytic protein G-D-S-L family
JWY35_RS11145	COG1999	signal sequence binding
JWY35_RS11155	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JWY35_RS11160	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JWY35_RS11165	COG1272	protein, Hemolysin III
JWY35_RS11170	COG0204	Acyl-transferase
JWY35_RS11175	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JWY35_RS11180	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JWY35_RS11190	COG2521	methyltransferase
JWY35_RS11190	COG2136	Putative SAM-dependent methyltransferase
JWY35_RS11200	COG0129	dihydroxy-acid dehydratase activity
JWY35_RS11205	COG1413	lyase activity
JWY35_RS11210	COG1418	mRNA catabolic process
JWY35_RS11215	COG0386	Belongs to the glutathione peroxidase family
JWY35_RS11220	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
JWY35_RS11225	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JWY35_RS11235	COG1278	Cold shock
JWY35_RS11255	COG0328	RNA-DNA hybrid ribonuclease activity
JWY35_RS11260	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JWY35_RS11265	COG0328	RNA-DNA hybrid ribonuclease activity
JWY35_RS11275	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JWY35_RS11290	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JWY35_RS11300	COG1755	Isoprenylcysteine carboxyl methyltransferase
JWY35_RS11305	COG3424	synthase
JWY35_RS11310	COG2233	PERMEase
JWY35_RS11315	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JWY35_RS11320	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
JWY35_RS11330	COG0800	Aldolase
JWY35_RS11335	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JWY35_RS11340	COG1609	Transcriptional regulator
JWY35_RS11345	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
JWY35_RS11350	COG1028	Short-chain dehydrogenase reductase Sdr
JWY35_RS11355	COG1199	ATP-dependent helicase activity
JWY35_RS11370	COG0116	Belongs to the methyltransferase superfamily
JWY35_RS11385	COG4474	Belongs to the UPF0398 family
JWY35_RS11400	COG3359	exonuclease
JWY35_RS11405	COG1205	dead DEAH box helicase
JWY35_RS11405	COG1111	helicase
JWY35_RS11410	COG2190	(PTS) system
JWY35_RS11415	COG0071	Belongs to the small heat shock protein (HSP20) family
JWY35_RS11450	COG3331	DNA recombination
JWY35_RS11455	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JWY35_RS11455	COG4499	WXG100 protein secretion system (Wss), protein YukC
JWY35_RS11465	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JWY35_RS11470	COG3935	DnaD domain protein
JWY35_RS11475	COG0017	Asparaginyl-tRNA synthetase
JWY35_RS11480	COG0436	Aminotransferase
JWY35_RS11485	COG5353	protein conserved in bacteria
JWY35_RS11495	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JWY35_RS11495	COG1199	ATP-dependent helicase activity
JWY35_RS11500	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JWY35_RS11505	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JWY35_RS11510	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JWY35_RS11515	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
JWY35_RS11515	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
JWY35_RS11520	COG0617	tRNA 3'-terminal CCA addition
JWY35_RS11525	COG0438	transferase activity, transferring glycosyl groups
JWY35_RS11530	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JWY35_RS11535	COG1803	Methylglyoxal synthase
JWY35_RS11540	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JWY35_RS11545	COG1694	Mazg nucleotide pyrophosphohydrolase
JWY35_RS11550	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JWY35_RS11560	COG4347	Protein of unknown function (DUF1405)
JWY35_RS11565	COG2010	Cytochrome c
JWY35_RS11565	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JWY35_RS11570	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JWY35_RS11575	COG0723	plastoquinol--plastocyanin reductase activity
JWY35_RS11585	COG5582	Belongs to the UPF0302 family
JWY35_RS11590	COG0457	Tetratricopeptide repeat
JWY35_RS11595	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JWY35_RS11600	COG0287	Prephenate dehydrogenase
JWY35_RS11615	COG0133	tryptophan synthase activity
JWY35_RS11620	COG0135	phosphoribosylanthranilate isomerase activity
JWY35_RS11630	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JWY35_RS11635	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JWY35_RS11640	COG4401	Chorismate mutase type I
JWY35_RS11645	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JWY35_RS11650	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JWY35_RS11655	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JWY35_RS11660	COG0105	UTP biosynthetic process
JWY35_RS11665	COG0142	geranyltranstransferase activity
JWY35_RS11670	COG2226	methyltransferase
JWY35_RS11675	COG0142	geranyltranstransferase activity
JWY35_RS11685	COG0302	gtp cyclohydrolase
JWY35_RS11690	COG0776	regulation of translation
JWY35_RS11695	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JWY35_RS11710	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JWY35_RS11715	COG1160	GTP binding
JWY35_RS11740	COG1304	FMN binding
JWY35_RS11745	COG0539	negative regulation of cytoplasmic translation
JWY35_RS11750	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JWY35_RS11760	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
JWY35_RS11765	COG2959	enzyme of heme biosynthesis
JWY35_RS11770	COG3773	Cell wall hydrolase
JWY35_RS11770	COG3409	Peptidoglycan-binding domain 1 protein
JWY35_RS11775	COG2339	peptidase activity
JWY35_RS11780	COG0492	ferredoxin-NADP+ reductase activity
JWY35_RS11785	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JWY35_RS11790	COG4862	establishment of competence for transformation
JWY35_RS11795	COG1408	metallophosphoesterase
JWY35_RS11805	COG1388	LysM domain
JWY35_RS11810	COG1266	CAAX protease self-immunity
JWY35_RS11815	COG0514	ATP-dependent DNA helicase (RecQ)
JWY35_RS11820	COG4955	Helix-turn-helix domain
JWY35_RS11825	COG1141	Ferredoxin
JWY35_RS11830	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JWY35_RS11835	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JWY35_RS11840	COG0710	3-dehydroquinate dehydratase activity
JWY35_RS11850	COG1595	DNA-templated transcription, initiation
JWY35_RS11855	COG5002	protein histidine kinase activity
JWY35_RS11860	COG0745	RESPONSE REGULATOR receiver
JWY35_RS11865	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JWY35_RS11870	COG1333	cytochrome c biogenesis protein
JWY35_RS11875	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JWY35_RS11880	COG1187	pseudouridine synthase activity
JWY35_RS11885	COG0700	Nucleoside recognition
JWY35_RS11890	COG2715	membrane protein required for spore maturation
JWY35_RS11895	COG1686	Belongs to the peptidase S11 family
JWY35_RS11905	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JWY35_RS11910	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JWY35_RS11915	COG1547	Domain of unknown function (DUF309)
JWY35_RS11920	COG0456	acetyltransferase
JWY35_RS11925	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JWY35_RS11930	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JWY35_RS11930	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JWY35_RS11935	COG0307	riboflavin synthase, alpha
JWY35_RS11940	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JWY35_RS11940	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JWY35_RS11950	COG0681	Belongs to the peptidase S26 family
JWY35_RS11960	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
JWY35_RS12005	COG3328	transposase activity
JWY35_RS12055	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JWY35_RS12065	COG4086	secreted protein
JWY35_RS12070	COG0019	diaminopimelate decarboxylase activity
JWY35_RS12075	COG0697	spore germination
JWY35_RS12090	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JWY35_RS12110	COG1191	sigma factor activity
JWY35_RS12115	COG2172	sigma factor antagonist activity
JWY35_RS12120	COG1366	Belongs to the anti-sigma-factor antagonist family
JWY35_RS12125	COG1686	Belongs to the peptidase S11 family
JWY35_RS12130	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JWY35_RS12135	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JWY35_RS12140	COG4974	Belongs to the 'phage' integrase family
JWY35_RS12150	COG0735	belongs to the Fur family
JWY35_RS12155	COG1300	Membrane
JWY35_RS12165	COG0281	malic enzyme
JWY35_RS12170	COG1757	Na H antiporter
JWY35_RS12175	COG1027	Aspartate ammonia-lyase
JWY35_RS12180	COG0252	asparaginase activity
JWY35_RS12185	COG1396	sequence-specific DNA binding
JWY35_RS12190	COG1379	DNA repair
JWY35_RS12195	COG0494	nUDIX hydrolase
JWY35_RS12205	COG0667	Aldo Keto reductase
JWY35_RS12215	COG1073	alpha beta
JWY35_RS12225	COG4918	Iron-sulphur cluster biosynthesis
JWY35_RS12230	COG0456	acetyltransferase
JWY35_RS12230	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JWY35_RS12235	COG2329	Antibiotic biosynthesis monooxygenase
JWY35_RS12240	COG0456	acetyltransferase
JWY35_RS12250	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JWY35_RS12260	COG2211	Major facilitator Superfamily
JWY35_RS12270	COG0346	lactoylglutathione lyase activity
JWY35_RS12275	COG1072	(Pantothenic acid kinase))
JWY35_RS12280	COG3048	D-serine ammonia-lyase activity
JWY35_RS12285	COG0300	oxidoreductase activity
JWY35_RS12290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JWY35_RS12295	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JWY35_RS12300	COG4187	Peptidase family M20/M25/M40
JWY35_RS12305	COG1902	pentaerythritol trinitrate reductase activity
JWY35_RS12320	COG0596	Alpha beta hydrolase
JWY35_RS12330	COG1234	tRNA 3'-trailer cleavage
JWY35_RS12335	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JWY35_RS12340	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JWY35_RS12345	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JWY35_RS12355	COG0706	membrane insertase activity
JWY35_RS12360	COG3361	conserved protein (COG2071)
JWY35_RS12365	COG2195	Cleaves the N-terminal amino acid of tripeptides
JWY35_RS12375	COG0346	lactoylglutathione lyase activity
JWY35_RS12385	COG1376	ErfK ybiS ycfS ynhG family protein
JWY35_RS12390	COG4129	membrane
JWY35_RS12395	COG1126	abc transporter atp-binding protein
JWY35_RS12400	COG0765	amino acid transport
JWY35_RS12405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JWY35_RS12415	COG1597	lipid kinase activity
JWY35_RS12425	COG0789	Transcriptional regulator
JWY35_RS12425	COG4978	Transcriptional regulator
JWY35_RS12430	COG0508	dehydrogenase complex catalyzes the overall conversion of
JWY35_RS12435	COG0022	dehydrogenase e1 component
JWY35_RS12440	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JWY35_RS12445	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JWY35_RS12450	COG3426	butyrate kinase activity
JWY35_RS12455	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JWY35_RS12460	COG0280	phosphate acetyltransferase
JWY35_RS12465	COG3290	protein histidine kinase activity
JWY35_RS12465	COG3829	transcription factor binding
JWY35_RS12475	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JWY35_RS12480	COG2079	MmgE PrpD family protein
JWY35_RS12485	COG0372	Belongs to the citrate synthase family
JWY35_RS12490	COG1960	acyl-CoA dehydrogenase activity
JWY35_RS12495	COG1250	3-hydroxyacyl-CoA dehydrogenase
JWY35_RS12500	COG0183	Belongs to the thiolase family
JWY35_RS12505	COG0584	glycerophosphoryl diester phosphodiesterase
JWY35_RS12510	COG0860	N-Acetylmuramoyl-L-alanine amidase
JWY35_RS12525	COG1902	pentaerythritol trinitrate reductase activity
JWY35_RS12530	COG0745	RESPONSE REGULATOR receiver
JWY35_RS12535	COG0750	zinc metalloprotease
JWY35_RS12540	COG0497	DNA recombination
JWY35_RS12545	COG1438	arginine binding
JWY35_RS12550	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
JWY35_RS12555	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JWY35_RS12560	COG0142	geranyltranstransferase activity
JWY35_RS12565	COG1722	exodeoxyribonuclease VII activity
JWY35_RS12570	COG1570	exodeoxyribonuclease VII activity
JWY35_RS12575	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JWY35_RS12580	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JWY35_RS12585	COG1302	Protein conserved in bacteria
JWY35_RS12590	COG0439	Biotin carboxylase
JWY35_RS12595	COG0511	ligase activity, forming carbon-carbon bonds
JWY35_RS12640	COG3854	ATPases associated with a variety of cellular activities
JWY35_RS12650	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JWY35_RS12655	COG0006	proline dipeptidase activity
JWY35_RS12660	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JWY35_RS12670	COG3872	metal-dependent enzyme
JWY35_RS12680	COG1752	Esterase of the alpha-beta hydrolase superfamily
JWY35_RS12685	COG1321	iron dependent repressor
JWY35_RS12690	COG0095	Lipoate-protein ligase
JWY35_RS12695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JWY35_RS12700	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JWY35_RS12705	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JWY35_RS12710	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JWY35_RS12715	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JWY35_RS12730	COG1396	sequence-specific DNA binding
JWY35_RS12740	COG0681	Belongs to the peptidase S26 family
JWY35_RS12765	COG4940	Competence protein ComGF
JWY35_RS12775	COG4970	Tfp pilus assembly protein FimT
JWY35_RS12780	COG4537	Required for transformation and DNA binding
JWY35_RS12785	COG1459	type II secretion system
JWY35_RS12790	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JWY35_RS12795	COG0517	IMP dehydrogenase activity
JWY35_RS12800	COG0598	Magnesium transport protein CorA
JWY35_RS12805	COG1253	flavin adenine dinucleotide binding
JWY35_RS12810	COG1366	Belongs to the anti-sigma-factor antagonist family
JWY35_RS12820	COG1393	Belongs to the ArsC family
JWY35_RS12830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JWY35_RS12840	COG0011	TIGRFAM Protein of
JWY35_RS12850	COG2866	Carboxypeptidase
JWY35_RS12855	COG1368	sulfuric ester hydrolase activity
JWY35_RS12860	COG1940	carbohydrate kinase activity
JWY35_RS12865	COG4483	Protein conserved in bacteria
JWY35_RS12870	COG0705	Rhomboid family
JWY35_RS12870	COG0457	Tetratricopeptide repeat
JWY35_RS12880	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JWY35_RS12890	COG0438	transferase activity, transferring glycosyl groups
JWY35_RS12905	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JWY35_RS12910	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JWY35_RS12915	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JWY35_RS12920	COG0581	inorganic phosphate transmembrane transporter activity
JWY35_RS12925	COG0573	inorganic phosphate transmembrane transporter activity
JWY35_RS12930	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JWY35_RS12935	COG0768	penicillin binding
JWY35_RS12940	COG0477	Major facilitator Superfamily
JWY35_RS12945	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JWY35_RS12950	COG2839	Protein conserved in bacteria
JWY35_RS12955	COG5521	maltodextrose utilization protein MalA
JWY35_RS12960	COG1388	LysM domain
JWY35_RS12965	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JWY35_RS12970	COG4709	membrane
JWY35_RS12975	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
JWY35_RS12980	COG0735	belongs to the Fur family
JWY35_RS12985	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JWY35_RS12995	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JWY35_RS13000	COG0513	Belongs to the DEAD box helicase family
JWY35_RS13010	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JWY35_RS13015	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JWY35_RS13020	COG2384	SAM-dependent methyltransferase
JWY35_RS13025	COG2010	Cytochrome c
JWY35_RS13030	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JWY35_RS13035	COG0358	DNA primase activity
JWY35_RS13040	COG1671	Belongs to the UPF0178 family
JWY35_RS13045	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JWY35_RS13050	COG0517	IMP dehydrogenase activity
JWY35_RS13055	COG0751	glycine-tRNA ligase activity
JWY35_RS13060	COG0752	glycyl-tRNA synthetase alpha subunit
JWY35_RS13065	COG1381	Involved in DNA repair and RecF pathway recombination
JWY35_RS13075	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JWY35_RS13080	COG0295	cytidine deaminase activity
JWY35_RS13085	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JWY35_RS13090	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JWY35_RS13095	COG1480	7TM receptor with intracellular HD hydrolase
JWY35_RS13100	COG1702	phosphate starvation-inducible protein PhoH
JWY35_RS13105	COG0561	phosphatase activity
JWY35_RS13120	COG4864	UPF0365 protein
JWY35_RS13125	COG1030	water channel activity
JWY35_RS13130	COG1610	YqeY-like protein
JWY35_RS13140	COG1283	sodium-dependent phosphate transmembrane transporter activity
JWY35_RS13145	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JWY35_RS13150	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JWY35_RS13155	COG2264	protein methyltransferase activity
JWY35_RS13160	COG0484	heat shock protein binding
JWY35_RS13165	COG0443	Heat shock 70 kDa protein
JWY35_RS13170	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JWY35_RS13175	COG1420	regulation of RNA biosynthetic process
JWY35_RS13180	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JWY35_RS13185	COG0481	GTPase activity
JWY35_RS13195	COG0860	N-Acetylmuramoyl-L-alanine amidase
JWY35_RS13200	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
JWY35_RS13205	COG0268	Binds directly to 16S ribosomal RNA
JWY35_RS13210	COG1466	dna polymerase III delta subunit
JWY35_RS13225	COG2333	competence protein COMEC
JWY35_RS13225	COG0658	competence protein
JWY35_RS13230	COG2131	deaminase
JWY35_RS13235	COG1596	polysaccharide export
JWY35_RS13235	COG1555	photosystem II stabilization
JWY35_RS13240	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JWY35_RS13245	COG2226	methyltransferase
JWY35_RS13250	COG0799	negative regulation of ribosome biogenesis
JWY35_RS13255	COG1713	HD superfamily hydrolase involved in NAD metabolism
JWY35_RS13260	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JWY35_RS13265	COG1534	Rna-binding protein
JWY35_RS13270	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JWY35_RS13275	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JWY35_RS13280	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
JWY35_RS13290	COG2755	lipolytic protein G-D-S-L family
JWY35_RS13295	COG5632	N-Acetylmuramoyl-L-alanine amidase
JWY35_RS13295	COG3409	Peptidoglycan-binding domain 1 protein
JWY35_RS13300	COG0398	Pfam SNARE associated Golgi protein
JWY35_RS13305	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
JWY35_RS13315	COG3209	COG3209 Rhs family protein
JWY35_RS13335	COG0114	fumarate hydratase activity
JWY35_RS13340	COG0583	DNA-binding transcription factor activity
JWY35_RS13355	COG0457	Tetratricopeptide repeat
JWY35_RS13495	COG4978	Transcriptional regulator
JWY35_RS13495	COG0789	Transcriptional regulator
JWY35_RS13500	COG2814	Major facilitator Superfamily
JWY35_RS13505	COG0456	acetyltransferase
JWY35_RS13510	COG1253	flavin adenine dinucleotide binding
JWY35_RS13520	COG0697	spore germination
JWY35_RS13525	COG0583	DNA-binding transcription factor activity
JWY35_RS13530	COG2072	flavoprotein involved in K transport
JWY35_RS13535	COG1230	cation diffusion facilitator family transporter
JWY35_RS13550	COG1114	Component of the transport system for branched-chain amino acids
JWY35_RS13555	COG1687	branched-chain amino acid
JWY35_RS13565	COG1522	sequence-specific DNA binding
JWY35_RS13570	COG2732	(Barnase) inhibitor
JWY35_RS13575	COG2124	cytochrome p450
JWY35_RS13585	COG1335	isochorismatase
JWY35_RS13605	COG2318	DinB family
JWY35_RS13615	COG2070	2-Nitropropane dioxygenase
JWY35_RS13620	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JWY35_RS13640	COG3443	Belongs to the bacterial solute-binding protein 9 family
JWY35_RS13645	COG1595	DNA-templated transcription, initiation
JWY35_RS13650	COG0667	Aldo Keto reductase
JWY35_RS13655	COG3409	Peptidoglycan-binding domain 1 protein
JWY35_RS13660	COG5566	PFAM Mor transcription activator
JWY35_RS13665	COG0596	Alpha beta hydrolase
JWY35_RS13670	COG4991	sh3 domain protein
JWY35_RS13675	COG4991	sh3 domain protein
JWY35_RS13685	COG0346	lactoylglutathione lyase activity
JWY35_RS13695	COG5577	PFAM Coat F domain
JWY35_RS13700	COG1063	alcohol dehydrogenase
JWY35_RS13710	COG5577	PFAM Coat F domain
JWY35_RS13715	COG0789	Transcriptional regulator
JWY35_RS13725	COG1064	alcohol dehydrogenase
JWY35_RS13730	COG0693	protein deglycase activity
JWY35_RS13735	COG1621	beta-fructofuranosidase activity
JWY35_RS13740	COG3716	PTS system mannose fructose sorbose family IID component
JWY35_RS13745	COG3715	PTS system
JWY35_RS13750	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JWY35_RS13755	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
JWY35_RS13760	COG3933	PFAM sigma-54 factor interaction domain-containing protein
JWY35_RS13760	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JWY35_RS13770	COG1113	amino acid transport
JWY35_RS13775	COG1280	lysine exporter protein (LysE YggA)
JWY35_RS13780	COG1378	Sugar-specific transcriptional regulator TrmB
JWY35_RS13785	COG1595	DNA-templated transcription, initiation
JWY35_RS13810	COG1309	transcriptional regulator
JWY35_RS13815	COG2226	methyltransferase
JWY35_RS13830	COG2116	formate transmembrane transporter activity
JWY35_RS13835	COG5609	conserved protein (DUF2294)
JWY35_RS13840	COG3383	formate dehydrogenase (NAD+) activity
JWY35_RS13845	COG2427	Protein of unknown function (DUF1641)
JWY35_RS13860	COG0626	cystathionine gamma-synthase activity
JWY35_RS13865	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JWY35_RS13870	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JWY35_RS13875	COG2226	methyltransferase
JWY35_RS13890	COG0768	penicillin binding
JWY35_RS13895	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JWY35_RS13900	COG0572	uridine kinase
JWY35_RS13905	COG0826	peptidase U32
JWY35_RS13910	COG0826	peptidase U32
JWY35_RS13915	COG4122	O-methyltransferase activity
JWY35_RS13920	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JWY35_RS13925	COG3906	Belongs to the UPF0473 family
JWY35_RS13930	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JWY35_RS13935	COG4472	Bacterial protein of unknown function (DUF965)
JWY35_RS13940	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JWY35_RS13945	COG0628	permease
JWY35_RS13950	COG1126	abc transporter atp-binding protein
JWY35_RS13955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JWY35_RS13960	COG0765	amino acid transport
JWY35_RS13965	COG0765	amino acid transport
JWY35_RS13980	COG3881	PFAM PRC-barrel domain
JWY35_RS13985	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JWY35_RS13990	COG0457	Tetratricopeptide repeat
JWY35_RS13995	COG0482	sulfurtransferase activity
JWY35_RS14000	COG1104	cysteine desulfurase activity
JWY35_RS14005	COG1959	2 iron, 2 sulfur cluster binding
JWY35_RS14010	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JWY35_RS14015	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JWY35_RS14025	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JWY35_RS14030	COG0124	histidyl-tRNA synthetase
JWY35_RS14040	COG3103	Sh3 type 3 domain protein
JWY35_RS14040	COG0860	N-Acetylmuramoyl-L-alanine amidase
JWY35_RS14040	COG4991	sh3 domain protein
JWY35_RS14045	COG1490	D-aminoacyl-tRNA deacylase activity
JWY35_RS14050	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JWY35_RS14055	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JWY35_RS14060	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JWY35_RS14060	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JWY35_RS14065	COG5416	Lipopolysaccharide assembly protein A domain
JWY35_RS14070	COG0490	domain, Protein
JWY35_RS14075	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JWY35_RS14075	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JWY35_RS14085	COG2244	polysaccharide biosynthetic process
JWY35_RS14090	COG2323	membrane
JWY35_RS14100	COG1862	Preprotein translocase
JWY35_RS14105	COG0343	queuine tRNA-ribosyltransferase activity
JWY35_RS14110	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JWY35_RS14120	COG2255	four-way junction helicase activity
JWY35_RS14125	COG0632	four-way junction helicase activity
JWY35_RS14135	COG2814	Major facilitator Superfamily
JWY35_RS14140	COG0673	inositol 2-dehydrogenase activity
JWY35_RS14145	COG2112	serine threonine protein kinase
JWY35_RS14170	COG1115	amino acid carrier protein
JWY35_RS14175	COG0217	transcriptional regulatory protein
JWY35_RS14185	COG1388	LysM domain
JWY35_RS14190	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JWY35_RS14195	COG0157	Belongs to the NadC ModD family
JWY35_RS14200	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
JWY35_RS14205	COG1104	cysteine desulfurase activity
JWY35_RS14210	COG1827	regulation of RNA biosynthetic process
JWY35_RS14215	COG0077	Prephenate dehydratase
JWY35_RS14220	COG4492	Belongs to the UPF0735 family
JWY35_RS14225	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JWY35_RS14230	COG3290	protein histidine kinase activity
JWY35_RS14240	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JWY35_RS14245	COG2868	ribosomal protein
JWY35_RS14250	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JWY35_RS14255	COG1994	Peptidase M50
JWY35_RS14260	COG0739	heme binding
JWY35_RS14265	COG2894	cell division
JWY35_RS14270	COG0850	regulation of cytokinetic process
JWY35_RS14275	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
JWY35_RS14285	COG1077	Cell shape determining protein MreB Mrl
JWY35_RS14290	COG2003	Belongs to the UPF0758 family
JWY35_RS14295	COG0424	maF-like protein
JWY35_RS14305	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JWY35_RS14310	COG0285	dihydrofolate synthase activity
JWY35_RS14315	COG0525	valine-tRNA ligase activity
JWY35_RS14325	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JWY35_RS14330	COG1388	LysM domain
JWY35_RS14335	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JWY35_RS14340	COG0113	porphobilinogen synthase activity
JWY35_RS14345	COG1587	Uroporphyrinogen-III synthase
JWY35_RS14350	COG0181	hydroxymethylbilane synthase activity
JWY35_RS14355	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JWY35_RS14360	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JWY35_RS14370	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JWY35_RS14375	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JWY35_RS14380	COG0470	DNA polymerase III
JWY35_RS14380	COG1067	ATP-dependent peptidase activity
JWY35_RS14385	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JWY35_RS14390	COG0544	peptidyl-prolyl cis-trans isomerase activity
JWY35_RS14395	COG1477	protein flavinylation
JWY35_RS14395	COG0457	Tetratricopeptide repeat
JWY35_RS14400	COG0066	3-isopropylmalate dehydratase activity
JWY35_RS14405	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JWY35_RS14410	COG0473	3-isopropylmalate dehydrogenase activity
JWY35_RS14415	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JWY35_RS14420	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JWY35_RS14425	COG0440	acetolactate synthase activity
JWY35_RS14430	COG0028	Belongs to the TPP enzyme family
JWY35_RS14445	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
JWY35_RS14470	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
JWY35_RS14500	COG0622	Phosphoesterase
JWY35_RS14505	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JWY35_RS14510	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JWY35_RS14515	COG5401	PFAM Sporulation and spore germination
JWY35_RS14520	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JWY35_RS14525	COG1846	Transcriptional regulator
JWY35_RS14530	COG2197	response regulator
JWY35_RS14535	COG0824	Thioesterase
JWY35_RS14540	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JWY35_RS14545	COG1053	succinate dehydrogenase
JWY35_RS14550	COG2009	succinate dehydrogenase
JWY35_RS14555	COG1719	4-vinyl reductase, 4VR
JWY35_RS14560	COG0527	aspartate kinase activity
JWY35_RS14565	COG0322	excinuclease ABC activity
JWY35_RS14570	COG3118	belongs to the thioredoxin family
JWY35_RS14575	COG3534	alpha-L-arabinofuranosidase
JWY35_RS14580	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JWY35_RS14585	COG2086	electron transfer activity
JWY35_RS14590	COG1024	Enoyl-CoA hydratase
JWY35_RS14595	COG1309	transcriptional regulator
JWY35_RS14600	COG0318	PFAM AMP-dependent synthetase and ligase
JWY35_RS14605	COG3766	membrane
JWY35_RS14610	COG1193	negative regulation of DNA recombination
JWY35_RS14615	COG1796	DNA polymerase
JWY35_RS14615	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JWY35_RS14620	COG1286	toxin biosynthetic process
JWY35_RS14625	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JWY35_RS14630	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JWY35_RS14635	COG0072	phenylalanine-tRNA ligase activity
JWY35_RS14635	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JWY35_RS14640	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JWY35_RS14650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JWY35_RS14660	COG3835	regulator
JWY35_RS14665	COG0277	FAD linked oxidase domain protein
JWY35_RS14670	COG0247	lactate metabolic process
JWY35_RS14675	COG0346	lactoylglutathione lyase activity
JWY35_RS14685	COG1966	Carbon starvation protein
JWY35_RS14690	COG3534	alpha-L-arabinofuranosidase
JWY35_RS14695	COG0395	ABC-type sugar transport system, permease component
JWY35_RS14700	COG1175	transmembrane transport
JWY35_RS14705	COG1653	transport
JWY35_RS14710	COG0371	Dehydrogenase
JWY35_RS14715	COG0647	UMP catabolic process
JWY35_RS14720	COG0235	Class ii aldolase
JWY35_RS14725	COG1069	ribulokinase activity
JWY35_RS14730	COG2160	L-arabinose isomerase activity
JWY35_RS14740	COG1363	Peptidase, m42
JWY35_RS14750	COG3326	Membrane
JWY35_RS14755	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JWY35_RS14760	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JWY35_RS14765	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JWY35_RS14775	COG1346	cytolysis
JWY35_RS14780	COG1380	Effector of murein hydrolase LrgA
JWY35_RS14785	COG3279	Response regulator of the LytR AlgR family
JWY35_RS14790	COG3275	phosphorelay sensor kinase activity
JWY35_RS14795	COG1011	Hydrolase
JWY35_RS14800	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JWY35_RS14810	COG0398	Pfam SNARE associated Golgi protein
JWY35_RS14815	COG1484	DNA-dependent DNA replication
JWY35_RS14820	COG3611	Membrane attachment protein
JWY35_RS14825	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JWY35_RS14830	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
JWY35_RS14835	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JWY35_RS14840	COG1733	regulation of RNA biosynthetic process
JWY35_RS14845	COG2814	Major facilitator Superfamily
JWY35_RS14850	COG0656	L-ascorbic acid biosynthetic process
JWY35_RS14855	COG0237	dephospho-CoA kinase activity
JWY35_RS14865	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JWY35_RS14870	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JWY35_RS14870	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JWY35_RS14875	COG5002	protein histidine kinase activity
JWY35_RS14880	COG0745	RESPONSE REGULATOR receiver
JWY35_RS14885	COG0039	L-malate dehydrogenase activity
JWY35_RS14890	COG0538	isocitrate dehydrogenase activity
JWY35_RS14895	COG0372	Belongs to the citrate synthase family
JWY35_RS14900	COG2707	UPF0756 membrane protein
JWY35_RS14905	COG0628	permease
JWY35_RS14910	COG3030	protein affecting phage T7 exclusion by the F plasmid
JWY35_RS14915	COG0469	pyruvate kinase activity
JWY35_RS14920	COG0205	6-phosphofructokinase activity
JWY35_RS14925	COG0825	malonyl-CoA metabolic process
JWY35_RS14930	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JWY35_RS14935	COG0281	malic enzyme
JWY35_RS14940	COG0587	DNA-directed DNA polymerase activity
JWY35_RS14960	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JWY35_RS14970	COG4109	DRTGG domain
JWY35_RS14980	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JWY35_RS14985	COG1028	Short-chain dehydrogenase reductase Sdr
JWY35_RS14990	COG0165	Argininosuccinate lyase
JWY35_RS14995	COG0137	argininosuccinate synthase activity
JWY35_RS15000	COG0521	Mo-molybdopterin cofactor biosynthetic process
JWY35_RS15005	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JWY35_RS15015	COG0827	DNA restriction-modification system
JWY35_RS15020	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JWY35_RS15025	COG3874	Sporulation protein YtfJ
JWY35_RS15035	COG1714	RDD family
JWY35_RS15040	COG0616	signal peptide processing
JWY35_RS15045	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JWY35_RS15050	COG1574	metal-dependent hydrolase with the TIM-barrel fold
JWY35_RS15055	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JWY35_RS15065	COG0301	tRNA thio-modification
JWY35_RS15070	COG1104	cysteine desulfurase activity
JWY35_RS15075	COG1114	Component of the transport system for branched-chain amino acids
JWY35_RS15080	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JWY35_RS15085	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JWY35_RS15090	COG1309	transcriptional regulator
JWY35_RS15095	COG1956	GAF domain-containing protein
JWY35_RS15100	COG2203	Gaf domain
JWY35_RS15100	COG2199	diguanylate cyclase activity
JWY35_RS15105	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JWY35_RS15110	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JWY35_RS15115	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JWY35_RS15120	COG0454	-acetyltransferase
JWY35_RS15125	COG0517	IMP dehydrogenase activity
JWY35_RS15130	COG0123	including yeast histone deacetylase and acetoin utilization protein
JWY35_RS15135	COG1360	Flagellar Motor Protein
JWY35_RS15140	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JWY35_RS15145	COG1609	Transcriptional regulator
JWY35_RS15150	COG1605	Chorismate mutase
JWY35_RS15150	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JWY35_RS15155	COG3118	belongs to the thioredoxin family
JWY35_RS15160	COG4980	gas vesicle protein
JWY35_RS15165	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
JWY35_RS15170	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JWY35_RS15175	COG1674	ftsk spoiiie
JWY35_RS15180	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JWY35_RS15185	COG4848	Belongs to the UPF0354 family
JWY35_RS15190	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JWY35_RS15205	COG1363	Peptidase, m42
JWY35_RS15210	COG5584	Small secreted protein
JWY35_RS15215	COG0281	malic enzyme
JWY35_RS15220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JWY35_RS15225	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JWY35_RS15235	COG0510	thiamine kinase activity
JWY35_RS15240	COG1523	belongs to the glycosyl hydrolase 13 family
JWY35_RS15245	COG1597	lipid kinase activity
JWY35_RS15255	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JWY35_RS15260	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JWY35_RS15265	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JWY35_RS15270	COG2252	PERMEase
JWY35_RS15275	COG4473	ABC transporter
JWY35_RS15280	COG1131	(ABC) transporter
JWY35_RS15285	COG1349	DNA-binding transcription factor activity
JWY35_RS15290	COG1187	pseudouridine synthase activity
JWY35_RS15295	COG2244	polysaccharide biosynthetic process
JWY35_RS15300	COG2081	HI0933 family
JWY35_RS15305	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JWY35_RS15325	COG1653	transport
JWY35_RS15330	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
JWY35_RS15335	COG4209	transmembrane transport
JWY35_RS15345	COG1653	transport
JWY35_RS15350	COG0395	ABC-type sugar transport system, permease component
JWY35_RS15355	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JWY35_RS15360	COG2124	cytochrome p450
JWY35_RS15380	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JWY35_RS15390	COG1073	alpha beta
JWY35_RS15395	COG1609	Transcriptional regulator
JWY35_RS15400	COG1653	transport
JWY35_RS15405	COG1175	transmembrane transport
JWY35_RS15410	COG0395	ABC-type sugar transport system, permease component
JWY35_RS15415	COG1486	melibiose metabolic process
JWY35_RS15420	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JWY35_RS15425	COG0495	leucyl-tRNA aminoacylation
JWY35_RS15435	COG2202	Pas domain
JWY35_RS15435	COG1366	Belongs to the anti-sigma-factor antagonist family
JWY35_RS15440	COG2814	Major facilitator Superfamily
JWY35_RS15445	COG2433	Pfam Transposase IS66
JWY35_RS15450	COG0577	efflux transmembrane transporter activity
JWY35_RS15455	COG1136	(ABC) transporter
JWY35_RS15460	COG2205	protein histidine kinase activity
JWY35_RS15465	COG0745	RESPONSE REGULATOR receiver
JWY35_RS15470	COG0577	efflux transmembrane transporter activity
JWY35_RS15475	COG1136	(ABC) transporter
JWY35_RS15490	COG1131	(ABC) transporter
JWY35_RS15495	COG1725	Transcriptional regulator
JWY35_RS15510	COG1242	4 iron, 4 sulfur cluster binding
JWY35_RS15515	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
JWY35_RS15525	COG2267	carboxylic ester hydrolase activity
JWY35_RS15530	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JWY35_RS15535	COG1113	amino acid transport
JWY35_RS15540	COG0367	asparagine synthase
JWY35_RS15545	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JWY35_RS15550	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JWY35_RS15560	COG1506	peptidase
JWY35_RS15565	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JWY35_RS15570	COG1116	anion transmembrane transporter activity
JWY35_RS15575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JWY35_RS15580	COG0494	nUDIX hydrolase
JWY35_RS15585	COG4824	toxin secretion phage lysis holin
JWY35_RS15590	COG0783	Belongs to the Dps family
JWY35_RS15605	COG1854	S-ribosylhomocysteine lyase activity
JWY35_RS15610	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JWY35_RS15615	COG0288	reversible hydration of carbon dioxide
JWY35_RS15620	COG0254	rRNA binding
JWY35_RS15625	COG1271	oxidase subunit
JWY35_RS15630	COG1294	oxidase, subunit
JWY35_RS15640	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JWY35_RS15645	COG1321	iron dependent repressor
JWY35_RS15645	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JWY35_RS15650	COG1121	(ABC) transporter
JWY35_RS15655	COG0803	Belongs to the bacterial solute-binding protein 9 family
JWY35_RS15660	COG4948	Mandelate Racemase Muconate Lactonizing
JWY35_RS15665	COG0318	PFAM AMP-dependent synthetase and ligase
JWY35_RS15670	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JWY35_RS15675	COG0596	Alpha beta hydrolase
JWY35_RS15680	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JWY35_RS15685	COG1169	isochorismate synthase
JWY35_RS15690	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JWY35_RS15695	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JWY35_RS15700	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JWY35_RS15705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JWY35_RS15710	COG0438	transferase activity, transferring glycosyl groups
JWY35_RS15720	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JWY35_RS15725	COG0438	transferase activity, transferring glycosyl groups
JWY35_RS15730	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JWY35_RS15735	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
JWY35_RS15740	COG0058	SHG alpha-glucan phosphorylase activity
JWY35_RS15745	COG0297	glycogen (starch) synthase activity
JWY35_RS15750	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JWY35_RS15755	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JWY35_RS15760	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JWY35_RS15885	COG3859	Proton-coupled thiamine transporter YuaJ
JWY35_RS15890	COG1247	-acetyltransferase
JWY35_RS15895	COG2268	Band 7 protein
JWY35_RS15900	COG1585	Membrane protein implicated in regulation of membrane protease activity
JWY35_RS15905	COG2318	DinB family
JWY35_RS15915	COG1454	alcohol dehydrogenase
JWY35_RS15920	COG1012	belongs to the aldehyde dehydrogenase family
JWY35_RS15925	COG1510	regulation of RNA biosynthetic process
JWY35_RS15935	COG0569	domain protein
JWY35_RS15940	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JWY35_RS15945	COG4682	membrane
JWY35_RS15950	COG1705	Flagellar rod assembly protein muramidase FlgJ
JWY35_RS15955	COG0477	Major facilitator Superfamily
JWY35_RS15960	COG5553	Cysteine dioxygenase type I
JWY35_RS15970	COG1968	undecaprenyl-diphosphatase activity
JWY35_RS15975	COG0628	permease
JWY35_RS15980	COG0673	inositol 2-dehydrogenase activity
JWY35_RS15985	COG4806	L-rhamnose isomerase
JWY35_RS15990	COG3254	rhamnose metabolic process
JWY35_RS15995	COG1070	Carbohydrate kinase
JWY35_RS16000	COG1349	DNA-binding transcription factor activity
JWY35_RS16005	COG3347	Dehydrogenase
JWY35_RS16005	COG1028	Short-chain dehydrogenase reductase Sdr
JWY35_RS16015	COG0840	transmembrane signaling receptor activity
JWY35_RS16025	COG0840	transmembrane signaling receptor activity
JWY35_RS16040	COG0432	Pfam Uncharacterised protein family UPF0047
JWY35_RS16050	COG0366	Alpha amylase catalytic
JWY35_RS16055	COG1253	flavin adenine dinucleotide binding
JWY35_RS16060	COG2738	Putative neutral zinc metallopeptidase
JWY35_RS16075	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JWY35_RS16090	COG0166	Belongs to the GPI family
JWY35_RS16095	COG1979	alcohol dehydrogenase
JWY35_RS16100	COG1979	alcohol dehydrogenase
JWY35_RS16105	COG2155	Conserved Protein
JWY35_RS16110	COG1098	S1 RNA binding domain
JWY35_RS16115	COG0436	Aminotransferase
JWY35_RS16120	COG1522	sequence-specific DNA binding
JWY35_RS16125	COG2267	carboxylic ester hydrolase activity
JWY35_RS16135	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JWY35_RS16140	COG2205	protein histidine kinase activity
JWY35_RS16150	COG5018	Exonuclease
JWY35_RS16160	COG2814	Major facilitator Superfamily
JWY35_RS16165	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JWY35_RS16170	COG3011	Protein conserved in bacteria
JWY35_RS16180	COG3290	protein histidine kinase activity
JWY35_RS16185	COG4565	transcriptional regulatory protein
JWY35_RS16190	COG1744	ABC transporter substrate-binding protein PnrA-like
JWY35_RS16195	COG3845	ABC transporter
JWY35_RS16200	COG4603	Belongs to the binding-protein-dependent transport system permease family
JWY35_RS16205	COG1079	Belongs to the binding-protein-dependent transport system permease family
JWY35_RS16210	COG3493	citrate carrier protein
JWY35_RS16220	COG2111	Na H antiporter
JWY35_RS16220	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JWY35_RS16225	COG2111	Na H antiporter
JWY35_RS16230	COG1006	Multisubunit Na H antiporter MnhC subunit
JWY35_RS16235	COG0651	ATP synthesis coupled electron transport
JWY35_RS16240	COG1863	multisubunit Na H antiporter MnhE subunit
JWY35_RS16245	COG2212	antiporter activity
JWY35_RS16250	COG1320	monovalent cation:proton antiporter activity
JWY35_RS16255	COG2050	protein possibly involved in aromatic compounds catabolism
JWY35_RS16260	COG2197	response regulator
JWY35_RS16265	COG4585	Histidine kinase
JWY35_RS16275	COG0142	geranyltranstransferase activity
JWY35_RS16295	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
JWY35_RS16300	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JWY35_RS16305	COG1335	isochorismatase
JWY35_RS16310	COG5506	Protein of unknown function (DUF1694)
JWY35_RS16325	COG0628	permease
JWY35_RS16340	COG1418	mRNA catabolic process
JWY35_RS16345	COG1028	Short-chain dehydrogenase reductase Sdr
JWY35_RS16355	COG1511	domain protein
JWY35_RS16360	COG1674	ftsk spoiiie
JWY35_RS16360	COG0433	COG0433 Predicted ATPase
JWY35_RS16365	COG4499	WXG100 protein secretion system (Wss), protein YukC
JWY35_RS16370	COG5417	Belongs to the EsaB family
JWY35_RS16375	COG4842	Belongs to the WXG100 family
JWY35_RS16380	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JWY35_RS16380	COG2508	Transcriptional regulator
JWY35_RS16385	COG0686	Belongs to the AlaDH PNT family
JWY35_RS16390	COG5634	Uncharacterized conserved protein (DUF2278)
JWY35_RS16395	COG3251	PFAM MbtH domain protein
JWY35_RS16400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JWY35_RS16405	COG3433	isochorismatase activity
JWY35_RS16405	COG1535	isochorismatase
JWY35_RS16410	COG1021	2,3-dihydroxybenzoate-AMP ligase
JWY35_RS16415	COG1169	isochorismate synthase
JWY35_RS16420	COG1028	Short-chain dehydrogenase reductase Sdr
JWY35_RS16425	COG2819	hydrolase of the alpha beta superfamily
JWY35_RS16430	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JWY35_RS16435	COG1268	BioY protein
JWY35_RS16440	COG2056	Na+-H+ antiporter family
JWY35_RS16445	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JWY35_RS16450	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
JWY35_RS16455	COG3584	3D domain protein
JWY35_RS16470	COG1252	NADH dehydrogenase
JWY35_RS16475	COG0492	ferredoxin-NADP+ reductase activity
JWY35_RS16485	COG0516	GMP reductase activity
JWY35_RS16490	COG2808	Putative FMN-binding domain
JWY35_RS16495	COG0456	acetyltransferase
JWY35_RS16605	COG0582	viral genome integration into host DNA
JWY35_RS16615	COG4974	Belongs to the 'phage' integrase family
JWY35_RS16620	COG0316	Belongs to the HesB IscA family
JWY35_RS16625	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JWY35_RS16630	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JWY35_RS16635	COG4844	belongs to the
JWY35_RS16640	COG1252	NADH dehydrogenase
JWY35_RS16645	COG4837	Protein of unknown function (DUF1462)
JWY35_RS16650	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
JWY35_RS16655	COG4946	Tricorn protease homolog
JWY35_RS16655	COG1506	peptidase
JWY35_RS16655	COG0823	Involved in the tonB-independent uptake of proteins
JWY35_RS16660	COG0083	homoserine kinase activity
JWY35_RS16665	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JWY35_RS16670	COG0460	homoserine dehydrogenase
JWY35_RS16675	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JWY35_RS16680	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JWY35_RS16685	COG0647	UMP catabolic process
JWY35_RS16690	COG2445	Protein of unknown function DUF86
JWY35_RS16695	COG4470	Protein conserved in bacteria
JWY35_RS16705	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JWY35_RS16710	COG0739	heme binding
JWY35_RS16720	COG3377	Domain of unknown function (DUF1805)
JWY35_RS16725	COG0737	Belongs to the 5'-nucleotidase family
JWY35_RS16730	COG0730	response to heat
JWY35_RS16735	COG1801	Protein of unknown function DUF72
JWY35_RS16745	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JWY35_RS16750	COG2508	Transcriptional regulator
JWY35_RS16755	COG2233	PERMEase
JWY35_RS16760	COG2233	PERMEase
JWY35_RS16765	COG3195	allantoin biosynthetic process
JWY35_RS16765	COG3648	Uricase
JWY35_RS16770	COG2351	hydroxyisourate hydrolase activity
JWY35_RS16780	COG2080	2 iron, 2 sulfur cluster binding
JWY35_RS16785	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JWY35_RS16790	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
JWY35_RS16795	COG2068	MobA-Related Protein
JWY35_RS16800	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
JWY35_RS16805	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JWY35_RS16810	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JWY35_RS16820	COG2356	endonuclease I
JWY35_RS16825	COG3842	ATPase activity
JWY35_RS16830	COG2188	Transcriptional regulator
JWY35_RS16835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JWY35_RS16845	COG1175	transmembrane transport
JWY35_RS16850	COG1653	transport
JWY35_RS16855	COG2222	sugar isomerase
JWY35_RS16860	COG0322	excinuclease ABC activity
JWY35_RS16865	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JWY35_RS16880	COG0346	lactoylglutathione lyase activity
JWY35_RS16885	COG0640	Transcriptional regulator
JWY35_RS16890	COG0719	Fe-S assembly protein
JWY35_RS16895	COG0822	iron-sulfur transferase activity
JWY35_RS16900	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JWY35_RS16905	COG0719	Fe-S assembly protein
JWY35_RS16910	COG0396	ATPase activity
JWY35_RS16925	COG1464	Belongs to the NlpA lipoprotein family
JWY35_RS16930	COG2011	ABC-type metal ion transport system permease component
JWY35_RS16935	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JWY35_RS16945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JWY35_RS16950	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JWY35_RS16960	COG0509	glycine decarboxylation via glycine cleavage system
JWY35_RS16965	COG1393	Belongs to the ArsC family
JWY35_RS16970	COG1960	acyl-CoA dehydrogenase activity
JWY35_RS16975	COG0183	Belongs to the thiolase family
JWY35_RS16980	COG1250	3-hydroxyacyl-CoA dehydrogenase
JWY35_RS16980	COG1024	Enoyl-CoA hydratase
JWY35_RS17000	COG5577	PFAM Coat F domain
JWY35_RS17005	COG1846	Transcriptional regulator
JWY35_RS17010	COG0477	Major facilitator Superfamily
JWY35_RS17015	COG1942	4-Oxalocrotonate Tautomerase
JWY35_RS17020	COG1028	Short-chain dehydrogenase reductase Sdr
JWY35_RS17025	COG0583	DNA-binding transcription factor activity
JWY35_RS17035	COG1120	ATPase activity
JWY35_RS17055	COG1131	(ABC) transporter
JWY35_RS17100	COG0783	Belongs to the Dps family
JWY35_RS17105	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JWY35_RS17110	COG0745	RESPONSE REGULATOR receiver
JWY35_RS17115	COG2770	Histidine kinase
JWY35_RS17115	COG2205	protein histidine kinase activity
JWY35_RS17125	COG1309	transcriptional regulator
JWY35_RS17130	COG0114	fumarate hydratase activity
JWY35_RS17140	COG0697	spore germination
JWY35_RS17145	COG0814	amino acid
JWY35_RS17155	COG2197	response regulator
JWY35_RS17160	COG4585	Histidine kinase
JWY35_RS17165	COG4758	membrane
JWY35_RS17170	COG3595	metallopeptidase activity
JWY35_RS17175	COG1842	Phage shock protein A
JWY35_RS17180	COG4758	membrane
JWY35_RS17185	COG2814	Major facilitator Superfamily
JWY35_RS17190	COG2096	Adenosyltransferase
JWY35_RS17195	COG1120	ATPase activity
JWY35_RS17200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JWY35_RS17205	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JWY35_RS17210	COG1028	Short-chain dehydrogenase reductase Sdr
JWY35_RS17215	COG3386	PFAM SMP-30 Gluconolaconase
JWY35_RS17220	COG2205	protein histidine kinase activity
JWY35_RS17225	COG0745	RESPONSE REGULATOR receiver
JWY35_RS17245	COG2140	Oxalate decarboxylase
JWY35_RS17255	COG0577	efflux transmembrane transporter activity
JWY35_RS17260	COG1136	(ABC) transporter
JWY35_RS17265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JWY35_RS17270	COG1120	ATPase activity
JWY35_RS17275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JWY35_RS17280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JWY35_RS17285	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JWY35_RS17290	COG0531	amino acid
JWY35_RS17300	COG1988	membrane-bound metal-dependent
JWY35_RS17305	COG1368	sulfuric ester hydrolase activity
JWY35_RS17310	COG1910	domain protein
JWY35_RS17315	COG0725	ABC transporter, periplasmic molybdate-binding protein
JWY35_RS17320	COG4149	molybdate abc transporter
JWY35_RS17325	COG0656	L-ascorbic acid biosynthetic process
JWY35_RS17335	COG0025	NhaP-type Na H and K H
JWY35_RS17340	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JWY35_RS17345	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JWY35_RS17350	COG3973	AAA domain
JWY35_RS17360	COG2860	membrane
JWY35_RS17365	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
JWY35_RS17370	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JWY35_RS17375	COG2217	Heavy metal translocating P-type atpase
JWY35_RS17380	COG2217	Heavy metal translocating P-type atpase
JWY35_RS17385	COG2608	mercury ion transmembrane transporter activity
JWY35_RS17390	COG1937	Protein conserved in bacteria
JWY35_RS17395	COG0673	inositol 2-dehydrogenase activity
JWY35_RS17405	COG1289	transmembrane transporter activity
JWY35_RS17415	COG2076	Multidrug Resistance protein
JWY35_RS17420	COG1309	transcriptional regulator
JWY35_RS17425	COG1028	Short-chain dehydrogenase reductase Sdr
JWY35_RS17435	COG5444	nuclease activity
JWY35_RS17450	COG5632	N-Acetylmuramoyl-L-alanine amidase
JWY35_RS17450	COG3409	Peptidoglycan-binding domain 1 protein
JWY35_RS17455	COG4824	toxin secretion phage lysis holin
JWY35_RS17480	COG3942	CHAP domain
JWY35_RS17480	COG1705	Flagellar rod assembly protein muramidase FlgJ
JWY35_RS17720	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JWY35_RS17725	COG0557	exoribonuclease II activity
JWY35_RS17730	COG1647	Serine aminopeptidase, S33
JWY35_RS17735	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JWY35_RS17740	COG0596	Alpha beta hydrolase
JWY35_RS17745	COG1476	TRANSCRIPTIONal
JWY35_RS17750	COG1396	sequence-specific DNA binding
JWY35_RS17755	COG1396	sequence-specific DNA binding
JWY35_RS17760	COG1733	regulation of RNA biosynthetic process
JWY35_RS17765	COG0840	transmembrane signaling receptor activity
JWY35_RS17770	COG1174	glycine betaine transport
JWY35_RS17775	COG1732	Glycine betaine
JWY35_RS17780	COG1174	glycine betaine transport
JWY35_RS17785	COG0517	IMP dehydrogenase activity
JWY35_RS17785	COG1125	glycine betaine transport
JWY35_RS17790	COG1510	regulation of RNA biosynthetic process
JWY35_RS17795	COG1174	glycine betaine transport
JWY35_RS17800	COG1732	Glycine betaine
JWY35_RS17805	COG1174	glycine betaine transport
JWY35_RS17810	COG1125	glycine betaine transport
JWY35_RS17810	COG0517	IMP dehydrogenase activity
JWY35_RS17815	COG1510	regulation of RNA biosynthetic process
JWY35_RS17820	COG2095	MarC family integral membrane protein
JWY35_RS17830	COG3064	Membrane
JWY35_RS17835	COG4640	response to antibiotic
JWY35_RS17840	COG0456	acetyltransferase
JWY35_RS17845	COG0148	phosphopyruvate hydratase activity
JWY35_RS17850	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JWY35_RS17855	COG0149	triose-phosphate isomerase activity
JWY35_RS17860	COG0126	phosphoglycerate kinase activity
JWY35_RS17865	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JWY35_RS17870	COG2390	Transcriptional regulator
JWY35_RS17875	COG2814	Major facilitator Superfamily
JWY35_RS17880	COG1609	Transcriptional regulator
JWY35_RS17885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JWY35_RS17890	COG0583	DNA-binding transcription factor activity
JWY35_RS17895	COG0697	spore germination
JWY35_RS17900	COG1113	amino acid transport
JWY35_RS17910	COG1556	Lactate utilization protein
JWY35_RS17915	COG1139	Iron-sulfur cluster binding protein
JWY35_RS17920	COG0247	lactate metabolic process
JWY35_RS17925	COG2197	response regulator
JWY35_RS17930	COG4585	Histidine kinase
JWY35_RS17935	COG0842	Transport permease protein
JWY35_RS17940	COG1131	(ABC) transporter
JWY35_RS17960	COG0596	Alpha beta hydrolase
JWY35_RS17965	COG2208	phosphoserine phosphatase activity
JWY35_RS17970	COG3867	Arabinogalactan endo-beta-1,4-galactanase
JWY35_RS17975	COG1874	Beta-galactosidase
JWY35_RS17980	COG3833	ABC-type maltose transport systems, permease component
JWY35_RS17985	COG1175	transmembrane transport
JWY35_RS17990	COG2182	Extracellular solute-binding protein
JWY35_RS17995	COG1609	Transcriptional regulator
JWY35_RS18000	COG2186	Transcriptional regulator
JWY35_RS18005	COG1620	l-lactate permease
JWY35_RS18010	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
JWY35_RS18020	COG5039	Polysaccharide pyruvyl transferase
JWY35_RS18025	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JWY35_RS18030	COG0110	maltose O-acetyltransferase activity
JWY35_RS18035	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JWY35_RS18040	COG2244	polysaccharide biosynthetic process
JWY35_RS18045	COG1216	Glycosyl transferase, family 2
JWY35_RS18050	COG5039	Polysaccharide pyruvyl transferase
JWY35_RS18055	COG1216	Glycosyl transferase, family 2
JWY35_RS18065	COG0438	transferase activity, transferring glycosyl groups
JWY35_RS18070	COG1215	transferase activity, transferring glycosyl groups
JWY35_RS18075	COG0438	transferase activity, transferring glycosyl groups
JWY35_RS18080	COG1086	Polysaccharide biosynthesis protein
JWY35_RS18085	COG0489	protein tyrosine kinase activity
JWY35_RS18090	COG3944	biosynthesis protein
JWY35_RS18095	COG1396	sequence-specific DNA binding
JWY35_RS18100	COG2272	Belongs to the type-B carboxylesterase lipase family
JWY35_RS18110	COG3479	Phenolic acid decarboxylase
JWY35_RS18125	COG1794	racemase activity, acting on amino acids and derivatives
JWY35_RS18135	COG1621	beta-fructofuranosidase activity
JWY35_RS18140	COG1621	beta-fructofuranosidase activity
JWY35_RS18145	COG0531	amino acid
JWY35_RS18150	COG1309	transcriptional regulator
JWY35_RS18155	COG2076	Multidrug Resistance protein
JWY35_RS18160	COG2076	Multidrug Resistance protein
JWY35_RS18180	COG1674	ftsk spoiiie
JWY35_RS18200	COG1388	LysM domain
JWY35_RS18200	COG3409	Peptidoglycan-binding domain 1 protein
JWY35_RS18200	COG5632	N-Acetylmuramoyl-L-alanine amidase
JWY35_RS18235	COG1705	Flagellar rod assembly protein muramidase FlgJ
JWY35_RS18315	COG0582	viral genome integration into host DNA
JWY35_RS18420	COG4974	Belongs to the 'phage' integrase family
JWY35_RS18430	COG0740	serine-type endopeptidase activity
JWY35_RS18435	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JWY35_RS18440	COG0366	Alpha amylase catalytic
JWY35_RS18445	COG1554	hydrolase, family 65, central catalytic
JWY35_RS18450	COG5521	maltodextrose utilization protein MalA
JWY35_RS18455	COG3833	ABC-type maltose transport systems, permease component
JWY35_RS18460	COG1175	transmembrane transport
JWY35_RS18465	COG2182	Extracellular solute-binding protein
JWY35_RS18475	COG1609	Transcriptional regulator
JWY35_RS18480	COG1611	Belongs to the LOG family
JWY35_RS18490	COG0659	secondary active sulfate transmembrane transporter activity
JWY35_RS18495	COG0288	reversible hydration of carbon dioxide
JWY35_RS18500	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JWY35_RS18505	COG0577	efflux transmembrane transporter activity
JWY35_RS18510	COG1136	(ABC) transporter
JWY35_RS18515	COG5002	protein histidine kinase activity
JWY35_RS18520	COG0745	RESPONSE REGULATOR receiver
JWY35_RS18530	COG2162	N-hydroxyarylamine O-acetyltransferase activity
JWY35_RS18535	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JWY35_RS18540	COG1481	regulation of sporulation
JWY35_RS18545	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JWY35_RS18550	COG1660	Displays ATPase and GTPase activities
JWY35_RS18555	COG1051	belongs to the nudix hydrolase family
JWY35_RS18560	COG0492	ferredoxin-NADP+ reductase activity
JWY35_RS18565	COG3883	PFAM NLP P60 protein
JWY35_RS18565	COG0791	NLP P60 protein
JWY35_RS18570	COG0457	Tetratricopeptide repeat
JWY35_RS18575	COG1132	(ABC) transporter
JWY35_RS18595	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JWY35_RS18595	COG0140	phosphoribosyl-ATP diphosphatase activity
JWY35_RS18600	COG0107	imidazoleglycerol-phosphate synthase activity
JWY35_RS18605	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JWY35_RS18610	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JWY35_RS18615	COG0131	Imidazoleglycerol-phosphate dehydratase
JWY35_RS18620	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JWY35_RS18625	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JWY35_RS18630	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
JWY35_RS18635	COG4990	cell redox homeostasis
JWY35_RS18640	COG5297	Belongs to the glycosyl hydrolase family 6
JWY35_RS18655	COG0546	phosphoglycolate phosphatase activity
JWY35_RS18660	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
JWY35_RS18665	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JWY35_RS18670	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JWY35_RS18675	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JWY35_RS18680	COG0363	glucosamine-6-phosphate deaminase activity
JWY35_RS18685	COG2188	Transcriptional regulator
JWY35_RS18690	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JWY35_RS18705	COG1950	PFAM Membrane protein of
JWY35_RS18710	COG1983	PspC domain protein
JWY35_RS18715	COG3595	metallopeptidase activity
JWY35_RS18730	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JWY35_RS18735	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JWY35_RS18740	COG0556	nucleotide-excision repair
JWY35_RS18745	COG4897	Protein conserved in bacteria
JWY35_RS18750	COG3848	Pyruvate phosphate dikinase
JWY35_RS18750	COG0574	Belongs to the PEP-utilizing enzyme family
JWY35_RS18755	COG1309	transcriptional regulator
JWY35_RS18760	COG2814	Major facilitator Superfamily
JWY35_RS18765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JWY35_RS18775	COG0793	Belongs to the peptidase S41A family
JWY35_RS18775	COG3409	Peptidoglycan-binding domain 1 protein
JWY35_RS18780	COG2177	Part of the ABC transporter FtsEX involved in
JWY35_RS18785	COG2884	Cell division ATP-binding protein ftsE
JWY35_RS18790	COG2010	Cytochrome c
JWY35_RS18795	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JWY35_RS18805	COG0653	protein targeting
JWY35_RS18810	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JWY35_RS18825	COG1516	flagellar protein fliS
JWY35_RS18830	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
JWY35_RS18835	COG1334	flagellar protein FlaG
JWY35_RS18840	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JWY35_RS18845	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
JWY35_RS18850	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
JWY35_RS18860	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JWY35_RS18865	COG1256	bacterial-type flagellum assembly
JWY35_RS18865	COG4786	Flagellar basal body rod
JWY35_RS18870	COG3418	PFAM FlgN family protein
JWY35_RS18875	COG2747	anti-sigma28 factor FlgM
JWY35_RS18885	COG1040	competence protein
JWY35_RS18895	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JWY35_RS18900	COG1307	EDD domain protein, DegV family
JWY35_RS18905	COG2197	response regulator
JWY35_RS18910	COG4585	Histidine kinase
JWY35_RS18915	COG1739	Uncharacterized protein family UPF0029
JWY35_RS18950	COG1131	(ABC) transporter
JWY35_RS18960	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JWY35_RS18965	COG0438	transferase activity, transferring glycosyl groups
JWY35_RS18970	COG1215	transferase activity, transferring glycosyl groups
JWY35_RS18975	COG3206	protein involved in exopolysaccharide biosynthesis
JWY35_RS18980	COG3307	-O-antigen
JWY35_RS18985	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JWY35_RS18990	COG0438	transferase activity, transferring glycosyl groups
JWY35_RS18990	COG0297	glycogen (starch) synthase activity
JWY35_RS18995	COG2244	polysaccharide biosynthetic process
JWY35_RS19010	COG0860	N-Acetylmuramoyl-L-alanine amidase
JWY35_RS19010	COG2247	cell wall binding repeat
JWY35_RS19015	COG2247	cell wall binding repeat
JWY35_RS19015	COG2385	sporulation resulting in formation of a cellular spore
JWY35_RS19050	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JWY35_RS19055	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JWY35_RS19070	COG1682	transport, permease protein
JWY35_RS19080	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JWY35_RS19080	COG0463	Glycosyl transferase, family 2
JWY35_RS19085	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JWY35_RS19090	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JWY35_RS19095	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
JWY35_RS19100	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JWY35_RS19105	COG4193	domain, Protein
JWY35_RS19110	COG1482	cell wall glycoprotein biosynthetic process
JWY35_RS19115	COG0697	spore germination
JWY35_RS19120	COG0814	amino acid
JWY35_RS19135	COG1316	TRANSCRIPTIONal
JWY35_RS19140	COG0561	phosphatase activity
JWY35_RS19145	COG0791	NLP P60 protein
JWY35_RS19155	COG2843	Capsule synthesis protein
JWY35_RS19165	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JWY35_RS19170	COG1609	Transcriptional regulator
JWY35_RS19175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JWY35_RS19180	COG1869	D-ribose catabolic process
JWY35_RS19185	COG1129	ABC transporter
JWY35_RS19190	COG1172	Belongs to the binding-protein-dependent transport system permease family
JWY35_RS19195	COG1879	ABC-type sugar transport system periplasmic component
JWY35_RS19200	COG3103	Sh3 type 3 domain protein
JWY35_RS19210	COG2249	NAD(P)H dehydrogenase (quinone) activity
JWY35_RS19215	COG3527	Alpha-acetolactate decarboxylase
JWY35_RS19220	COG0028	Belongs to the TPP enzyme family
JWY35_RS19225	COG0583	DNA-binding transcription factor activity
JWY35_RS19230	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JWY35_RS19245	COG5337	Spore coat protein CotH
JWY35_RS19255	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JWY35_RS19265	COG0405	Gamma-glutamyltransferase
JWY35_RS19270	COG1522	sequence-specific DNA binding
JWY35_RS19275	COG2059	Chromate
JWY35_RS19280	COG2059	Chromate
JWY35_RS19290	COG0655	NAD(P)H dehydrogenase (quinone) activity
JWY35_RS19295	COG0583	DNA-binding transcription factor activity
JWY35_RS19355	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JWY35_RS19360	COG4464	protein tyrosine phosphatase activity
JWY35_RS19365	COG0489	protein tyrosine kinase activity
JWY35_RS19370	COG3944	biosynthesis protein
JWY35_RS19380	COG4715	Zinc finger, swim domain protein
JWY35_RS19385	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JWY35_RS19390	COG0561	phosphatase activity
JWY35_RS19395	COG1349	DNA-binding transcription factor activity
JWY35_RS19400	COG0629	single-stranded DNA binding
JWY35_RS19420	COG0745	RESPONSE REGULATOR receiver
JWY35_RS19420	COG2972	Histidine kinase
JWY35_RS19425	COG1970	mechanosensitive ion channel activity
JWY35_RS19430	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JWY35_RS19435	COG0457	Tetratricopeptide repeat
JWY35_RS19440	COG4786	Flagellar basal body rod
JWY35_RS19445	COG4786	Flagellar basal body rod
JWY35_RS19450	COG1077	Cell shape determining protein MreB Mrl
JWY35_RS19455	COG1609	Transcriptional regulator
JWY35_RS19465	COG1846	Transcriptional regulator
JWY35_RS19470	COG2814	Major facilitator Superfamily
JWY35_RS19475	COG3420	alginic acid biosynthetic process
JWY35_RS19480	COG1953	Uracil, thiamine, allantoin
JWY35_RS19485	COG0477	Major facilitator Superfamily
JWY35_RS19490	COG1335	isochorismatase
JWY35_RS19500	COG0004	ammonium transporteR
JWY35_RS19505	COG0347	Belongs to the P(II) protein family
JWY35_RS19510	COG0671	phosphoesterase, PA-phosphatase related
JWY35_RS19520	COG0739	heme binding
JWY35_RS19525	COG1247	-acetyltransferase
JWY35_RS19535	COG2089	acid synthase
JWY35_RS19545	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JWY35_RS19550	COG0789	Transcriptional regulator
JWY35_RS19560	COG2910	NAD(P)H-binding
JWY35_RS19565	COG1959	2 iron, 2 sulfur cluster binding
JWY35_RS19570	COG0804	urea catabolic process
JWY35_RS19575	COG0832	Belongs to the urease beta subunit family
JWY35_RS19580	COG0831	urea catabolic process
JWY35_RS19595	COG3237	CsbD-like
JWY35_RS19600	COG1994	Peptidase M50
JWY35_RS19605	COG0457	Tetratricopeptide repeat
JWY35_RS19610	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JWY35_RS19615	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JWY35_RS19625	COG2304	oxidoreductase activity
JWY35_RS19635	COG2304	oxidoreductase activity
JWY35_RS19640	COG2385	sporulation resulting in formation of a cellular spore
JWY35_RS19645	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JWY35_RS19655	COG4836	Membrane
JWY35_RS19665	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JWY35_RS19670	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JWY35_RS19675	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JWY35_RS19680	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JWY35_RS19685	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JWY35_RS19690	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JWY35_RS19700	COG0356	it plays a direct role in the translocation of protons across the membrane
JWY35_RS19715	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JWY35_RS19720	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JWY35_RS19725	COG4475	Protein of unknown function (DUF436)
JWY35_RS19730	COG0698	ribose 5-phosphate isomerase
JWY35_RS19735	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JWY35_RS19740	COG1971	Probably functions as a manganese efflux pump
JWY35_RS19745	COG0009	L-threonylcarbamoyladenylate synthase
JWY35_RS19750	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
JWY35_RS19770	COG2890	protein-(glutamine-N5) methyltransferase activity
JWY35_RS19775	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JWY35_RS19780	COG0346	lactoylglutathione lyase activity
JWY35_RS19785	COG0789	Transcriptional regulator
JWY35_RS19790	COG0679	Auxin Efflux Carrier
JWY35_RS19795	COG0281	malic enzyme
JWY35_RS19800	COG1435	thymidine kinase activity
JWY35_RS19810	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JWY35_RS19820	COG1494	fructose-1,6-bisphosphatase
JWY35_RS19825	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JWY35_RS19835	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JWY35_RS19840	COG0191	fructose-bisphosphate aldolase activity
JWY35_RS19845	COG2204	response regulator
JWY35_RS19850	COG4821	SIS domain
JWY35_RS19855	COG0504	CTP synthase activity
JWY35_RS19860	COG3343	RNA polymerase activity
JWY35_RS19865	COG1960	acyl-CoA dehydrogenase activity
JWY35_RS19870	COG2181	nitrate reductase activity
JWY35_RS19870	COG0247	lactate metabolic process
JWY35_RS19875	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JWY35_RS19880	COG4294	response to UV
JWY35_RS19890	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JWY35_RS19900	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JWY35_RS19910	COG2181	nitrate reductase activity
JWY35_RS19915	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
JWY35_RS19920	COG1140	nitrate reductase beta subunit
JWY35_RS19925	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JWY35_RS19930	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JWY35_RS19940	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JWY35_RS19945	COG2223	nitrite transmembrane transporter activity
JWY35_RS19950	COG0018	arginyl-trna synthetase
JWY35_RS19955	COG4506	Protein conserved in bacteria
JWY35_RS19970	COG0535	radical SAM domain protein
JWY35_RS19980	COG1131	(ABC) transporter
JWY35_RS19985	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JWY35_RS19990	COG0612	Peptidase, M16
JWY35_RS19995	COG0612	Peptidase, M16
JWY35_RS20005	COG3391	amine dehydrogenase activity
JWY35_RS20010	COG3391	amine dehydrogenase activity
JWY35_RS20015	COG0457	Tetratricopeptide repeat
JWY35_RS20030	COG0010	Belongs to the arginase family
JWY35_RS20035	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JWY35_RS20040	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JWY35_RS20055	COG1994	Peptidase M50
JWY35_RS20060	COG1942	4-Oxalocrotonate Tautomerase
JWY35_RS20065	COG1846	Transcriptional regulator
JWY35_RS20070	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JWY35_RS20075	COG0477	Major facilitator Superfamily
JWY35_RS20080	COG1959	2 iron, 2 sulfur cluster binding
JWY35_RS20085	COG3465	dGTPase activity
JWY35_RS20090	COG1078	dGTPase activity
JWY35_RS20095	COG4844	belongs to the
JWY35_RS20105	COG0697	spore germination
JWY35_RS20110	COG0095	Lipoate-protein ligase
JWY35_RS20115	COG0583	DNA-binding transcription factor activity
JWY35_RS20120	COG0280	phosphate acetyltransferase
JWY35_RS20125	COG3253	May function as heme-dependent peroxidase
JWY35_RS20130	COG1028	Short-chain dehydrogenase reductase Sdr
JWY35_RS20135	COG0436	Aminotransferase
JWY35_RS20140	COG2814	Major facilitator Superfamily
JWY35_RS20145	COG0151	Belongs to the GarS family
JWY35_RS20150	COG1028	Short-chain dehydrogenase reductase Sdr
JWY35_RS20155	COG1917	Cupin 2, conserved barrel domain protein
JWY35_RS20160	COG0077	Prephenate dehydratase
JWY35_RS20165	COG2814	Major facilitator Superfamily
JWY35_RS20170	COG0833	amino acid
JWY35_RS20175	COG4187	Peptidase family M20/M25/M40
JWY35_RS20180	COG1012	belongs to the aldehyde dehydrogenase family
JWY35_RS20185	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JWY35_RS20195	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
JWY35_RS20200	COG1091	dTDP-4-dehydrorhamnose reductase activity
JWY35_RS20205	COG1088	dTDP-glucose 4,6-dehydratase activity
JWY35_RS20210	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JWY35_RS20215	COG3980	spore coat polysaccharide biosynthesis protein
JWY35_RS20220	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
JWY35_RS20225	COG2089	acid synthase
JWY35_RS20230	COG0456	acetyltransferase
JWY35_RS20235	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JWY35_RS20240	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JWY35_RS20245	COG0463	Glycosyl transferase, family 2
JWY35_RS20255	COG2363	Small membrane protein
JWY35_RS20260	COG2233	PERMEase
JWY35_RS20270	COG1012	belongs to the aldehyde dehydrogenase family
JWY35_RS20275	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JWY35_RS20280	COG1216	Glycosyl transferase, family 2
JWY35_RS20285	COG0351	phosphomethylpyrimidine kinase
JWY35_RS20295	COG1621	beta-fructofuranosidase activity
JWY35_RS20300	COG1263	PTS System
JWY35_RS20300	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JWY35_RS20305	COG2116	formate transmembrane transporter activity
JWY35_RS20320	COG1404	Belongs to the peptidase S8 family
JWY35_RS20325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JWY35_RS20330	COG0778	Nitroreductase
JWY35_RS20335	COG0772	Belongs to the SEDS family
JWY35_RS20350	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JWY35_RS20355	COG1845	cytochrome c oxidase, subunit III
JWY35_RS20360	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JWY35_RS20365	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JWY35_RS20370	COG2261	transglycosylase associated protein
JWY35_RS20375	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
JWY35_RS20380	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JWY35_RS20385	COG2246	polysaccharide biosynthetic process
JWY35_RS20390	COG1309	transcriptional regulator
JWY35_RS20400	COG3162	membrane
JWY35_RS20405	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JWY35_RS20410	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JWY35_RS20415	COG2837	iron assimilation
JWY35_RS20420	COG2822	iron ion transport
JWY35_RS20425	COG0672	)-iron permease
JWY35_RS20430	COG0352	thiamine-phosphate diphosphorylase activity
JWY35_RS20435	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JWY35_RS20440	COG0583	DNA-binding transcription factor activity
JWY35_RS20445	COG1380	Effector of murein hydrolase LrgA
JWY35_RS20450	COG1346	cytolysis
JWY35_RS20455	COG2814	Major facilitator Superfamily
JWY35_RS20460	COG4895	conserved protein (DUF2196)
JWY35_RS20465	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JWY35_RS20470	COG0346	lactoylglutathione lyase activity
JWY35_RS20485	COG1404	Belongs to the peptidase S8 family
JWY35_RS20490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JWY35_RS20490	COG1263	PTS System
JWY35_RS20495	COG3711	transcriptional antiterminator
JWY35_RS20500	COG1442	glycosyl transferase family 8
JWY35_RS20505	COG5522	Integral membrane protein (intg_mem_TP0381)
JWY35_RS20510	COG1846	Transcriptional regulator
JWY35_RS20515	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JWY35_RS20520	COG2234	aminopeptidase activity
JWY35_RS20525	COG2357	RelA SpoT domain protein
JWY35_RS20535	COG1575	Belongs to the MenA family. Type 1 subfamily
JWY35_RS20550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JWY35_RS20555	COG1696	Membrane protein involved in D-alanine export
JWY35_RS20560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JWY35_RS20565	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JWY35_RS20575	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JWY35_RS20580	COG1486	melibiose metabolic process
JWY35_RS20585	COG1447	Phosphotransferase system cellobiose-specific component IIA
JWY35_RS20590	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JWY35_RS20595	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JWY35_RS20600	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JWY35_RS20600	COG3711	transcriptional antiterminator
JWY35_RS20610	COG2094	Belongs to the DNA glycosylase MPG family
JWY35_RS20615	COG0753	catalase activity
JWY35_RS20620	COG2814	Major facilitator Superfamily
JWY35_RS20625	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
JWY35_RS20630	COG1131	(ABC) transporter
JWY35_RS20650	COG1595	DNA-templated transcription, initiation
JWY35_RS20655	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
JWY35_RS20660	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JWY35_RS20665	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JWY35_RS20670	COG4988	ABC transporter
JWY35_RS20675	COG1294	oxidase, subunit
JWY35_RS20680	COG1271	oxidase subunit
JWY35_RS20685	COG3493	citrate carrier protein
JWY35_RS20690	COG0501	Belongs to the peptidase M48B family
JWY35_RS20700	COG0726	polysaccharide deacetylase
JWY35_RS20705	COG3842	ATPase activity
JWY35_RS20710	COG2508	Transcriptional regulator
JWY35_RS20715	COG1012	belongs to the aldehyde dehydrogenase family
JWY35_RS20720	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JWY35_RS20725	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JWY35_RS20735	COG4585	Histidine kinase
JWY35_RS20740	COG2197	response regulator
JWY35_RS20745	COG2195	Cleaves the N-terminal amino acid of tripeptides
JWY35_RS20755	COG4894	glucomannan catabolic process
JWY35_RS20760	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JWY35_RS20765	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JWY35_RS20770	COG1028	Short-chain dehydrogenase reductase Sdr
JWY35_RS20775	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JWY35_RS20780	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JWY35_RS20785	COG2610	gluconate transmembrane transporter activity
JWY35_RS20790	COG0500	methyltransferase
JWY35_RS20795	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JWY35_RS20810	COG0693	protein deglycase activity
JWY35_RS20810	COG0753	catalase activity
JWY35_RS20815	COG2851	Citrate transporter
JWY35_RS20820	COG2273	Hydrolase Family 16
JWY35_RS20825	COG3711	transcriptional antiterminator
JWY35_RS20835	COG2270	Major facilitator Superfamily
JWY35_RS20840	COG0513	Belongs to the DEAD box helicase family
JWY35_RS20845	COG3401	FG-GAP repeat protein
JWY35_RS20845	COG2755	lipolytic protein G-D-S-L family
JWY35_RS20965	COG0697	spore germination
JWY35_RS20980	COG0589	response to stress
JWY35_RS20990	COG1263	PTS System
JWY35_RS20990	COG2190	(PTS) system
JWY35_RS20990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JWY35_RS21010	COG5444	nuclease activity
JWY35_RS21030	COG0494	nUDIX hydrolase
JWY35_RS21035	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
JWY35_RS21040	COG3507	Belongs to the glycosyl hydrolase 43 family
JWY35_RS21055	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
JWY35_RS21060	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JWY35_RS21065	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JWY35_RS21070	COG2390	Transcriptional regulator
JWY35_RS21080	COG3192	ethanolamine utilization protein
JWY35_RS21085	COG2079	MmgE PrpD family protein
JWY35_RS21090	COG1473	amidohydrolase
JWY35_RS21095	COG1126	abc transporter atp-binding protein
JWY35_RS21100	COG0765	amino acid transport
JWY35_RS21105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JWY35_RS21110	COG0456	acetyltransferase
JWY35_RS21115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JWY35_RS21120	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
JWY35_RS21125	COG0561	phosphatase activity
JWY35_RS21155	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JWY35_RS21160	COG5294	Protein conserved in bacteria
JWY35_RS21175	COG2205	protein histidine kinase activity
JWY35_RS21180	COG0745	RESPONSE REGULATOR receiver
JWY35_RS21185	COG0191	fructose-bisphosphate aldolase activity
JWY35_RS21190	COG1082	Xylose isomerase domain protein TIM barrel
JWY35_RS21195	COG1082	Xylose isomerase domain protein TIM barrel
JWY35_RS21200	COG0673	inositol 2-dehydrogenase activity
JWY35_RS21205	COG2814	Major facilitator Superfamily
JWY35_RS21210	COG1082	Xylose isomerase domain protein TIM barrel
JWY35_RS21215	COG3962	Belongs to the TPP enzyme family
JWY35_RS21220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JWY35_RS21240	COG1349	DNA-binding transcription factor activity
JWY35_RS21245	COG0667	Aldo Keto reductase
JWY35_RS21275	COG0326	Molecular chaperone. Has ATPase activity
JWY35_RS21330	COG1917	Cupin 2, conserved barrel domain protein
JWY35_RS21335	COG1309	transcriptional regulator
JWY35_RS21340	COG1028	Short-chain dehydrogenase reductase Sdr
JWY35_RS21345	COG1846	Transcriptional regulator
JWY35_RS21350	COG1380	Effector of murein hydrolase LrgA
JWY35_RS21355	COG1346	cytolysis
JWY35_RS21360	COG5039	Polysaccharide pyruvyl transferase
JWY35_RS21365	COG1929	Belongs to the glycerate kinase type-1 family
JWY35_RS21370	COG1802	Transcriptional regulator
JWY35_RS21375	COG1070	Carbohydrate kinase
JWY35_RS21380	COG2610	gluconate transmembrane transporter activity
JWY35_RS21385	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JWY35_RS21390	COG0450	alkyl hydroperoxide reductase
JWY35_RS21395	COG3634	alkyl hydroperoxide reductase activity
JWY35_RS21400	COG2723	6-phospho-beta-galactosidase activity
JWY35_RS21405	COG2190	(PTS) system
JWY35_RS21415	COG2188	Transcriptional regulator
JWY35_RS21425	COG1131	(ABC) transporter
JWY35_RS21430	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
JWY35_RS21440	COG0071	Belongs to the small heat shock protein (HSP20) family
JWY35_RS21470	COG0210	DNA helicase
JWY35_RS21500	COG2963	transposase activity
JWY35_RS21535	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JWY35_RS21550	COG1063	alcohol dehydrogenase
JWY35_RS21570	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
JWY35_RS21575	COG0456	acetyltransferase
JWY35_RS21580	COG0457	Tetratricopeptide repeat
JWY35_RS21590	COG0010	Belongs to the arginase family
JWY35_RS21595	COG0833	amino acid
JWY35_RS21600	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JWY35_RS21620	COG5658	integral membrane protein
JWY35_RS21625	COG0640	Transcriptional regulator
JWY35_RS21630	COG3829	transcription factor binding
JWY35_RS21645	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JWY35_RS21650	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JWY35_RS21655	COG4853	Protein conserved in bacteria
JWY35_RS21660	COG4863	YycH protein
JWY35_RS21665	COG5002	protein histidine kinase activity
JWY35_RS21670	COG0745	RESPONSE REGULATOR receiver
JWY35_RS21700	COG0346	lactoylglutathione lyase activity
JWY35_RS21705	COG0305	Participates in initiation and elongation during chromosome replication
JWY35_RS21720	COG3093	addiction module antidote protein HigA
JWY35_RS21725	COG2807	transmembrane transport
JWY35_RS21730	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JWY35_RS21735	COG0359	binds to the 23S rRNA
JWY35_RS21740	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
JWY35_RS21745	COG4241	membrane
JWY35_RS21760	COG1733	regulation of RNA biosynthetic process
JWY35_RS21765	COG1227	inorganic diphosphatase activity
JWY35_RS21780	COG2271	Major facilitator Superfamily
JWY35_RS21785	COG0789	Transcriptional regulator
JWY35_RS21785	COG4978	Transcriptional regulator
JWY35_RS21795	COG4319	ketosteroid isomerase
JWY35_RS21800	COG1357	PFAM Pentapeptide repeats (8 copies)
JWY35_RS21815	COG1846	Transcriptional regulator
JWY35_RS21820	COG2153	protein acetylation
JWY35_RS21825	COG2364	Membrane
JWY35_RS21830	COG0456	acetyltransferase
JWY35_RS21835	COG2315	Protein conserved in bacteria
JWY35_RS21840	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JWY35_RS21850	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
JWY35_RS21855	COG1331	Highly conserved protein containing a thioredoxin domain
JWY35_RS21860	COG1266	CAAX protease self-immunity
JWY35_RS21865	COG0477	Major facilitator Superfamily
JWY35_RS21865	COG2814	Major facilitator Superfamily
JWY35_RS21870	COG0346	lactoylglutathione lyase activity
JWY35_RS21875	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JWY35_RS21880	COG0542	response to heat
JWY35_RS21895	COG0708	Exodeoxyribonuclease III
JWY35_RS21900	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JWY35_RS21905	COG0629	single-stranded DNA binding
JWY35_RS21910	COG0360	Binds together with S18 to 16S ribosomal RNA
JWY35_RS21915	COG0012	GTP binding
JWY35_RS21920	COG0243	molybdopterin cofactor binding
JWY35_RS21925	COG4481	Protein conserved in bacteria
JWY35_RS21930	COG3949	Membrane
JWY35_RS21940	COG1475	DNA binding
JWY35_RS21945	COG1192	Involved in chromosome partitioning
JWY35_RS21955	COG1475	DNA binding
JWY35_RS21960	COG0357	Ribosomal RNA small subunit methyltransferase G
JWY35_RS21965	COG0445	tRNA wobble uridine modification
JWY35_RS21970	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JWY35_RS21975	COG1847	R3H domain protein
JWY35_RS21980	COG0706	membrane insertase activity
JWY35_RS21985	COG0594	ribonuclease P activity
JWY35_RS22010	COG0629	single-stranded DNA binding
JWY35_RS22215	COG0457	Tetratricopeptide repeat
JWY35_RS22260	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JWY35_RS22365	COG1525	nuclease
JWY35_RS22380	COG1793	dna ligase