locus-tag	class	description
GII81_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GII81_RS00010	COG0592	DNA-directed DNA polymerase activity
GII81_RS00015	COG2501	S4 domain
GII81_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GII81_RS00030	COG0187	DNA topoisomerase II activity
GII81_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GII81_RS00070	COG0517	IMP dehydrogenase activity
GII81_RS00070	COG0516	GMP reductase activity
GII81_RS00075	COG1686	Belongs to the peptidase S11 family
GII81_RS00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GII81_RS00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GII81_RS00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GII81_RS00100	COG1428	Deoxynucleoside kinase
GII81_RS00105	COG1428	Deoxynucleoside kinase
GII81_RS00110	COG3858	chitin binding
GII81_RS00110	COG1388	LysM domain
GII81_RS00115	COG1335	isochorismatase
GII81_RS00120	COG0590	tRNA wobble adenosine to inosine editing
GII81_RS00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GII81_RS00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GII81_RS00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GII81_RS00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
GII81_RS00190	COG3853	Toxic anion resistance protein (TelA)
GII81_RS00195	COG1982	Orn Lys Arg decarboxylase major
GII81_RS00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GII81_RS00205	COG3870	Protein conserved in bacteria
GII81_RS00210	COG1728	Protein conserved in bacteria
GII81_RS00215	COG0470	DNA polymerase III
GII81_RS00220	COG1774	PSP1 C-terminal conserved region
GII81_RS00225	COG4467	Involved in initiation control of chromosome replication
GII81_RS00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GII81_RS00235	COG2827	Endonuclease containing a URI domain
GII81_RS00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GII81_RS00245	COG2002	toxin-antitoxin pair type II binding
GII81_RS00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII81_RS00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII81_RS00255	COG0084	hydrolase, TatD family'
GII81_RS00260	COG3584	3D domain protein
GII81_RS00260	COG3583	domain protein
GII81_RS00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GII81_RS00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GII81_RS00280	COG4466	Protein conserved in bacteria
GII81_RS00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GII81_RS00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GII81_RS00300	COG0251	oxidation-reduction process
GII81_RS00305	COG2088	sporulation resulting in formation of a cellular spore
GII81_RS00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GII81_RS00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GII81_RS00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GII81_RS00325	COG0193	aminoacyl-tRNA hydrolase activity
GII81_RS00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GII81_RS00340	COG2002	toxin-antitoxin pair type II binding
GII81_RS00345	COG2244	polysaccharide biosynthetic process
GII81_RS00350	COG3956	TIGRFAM MazG family protein
GII81_RS00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GII81_RS00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GII81_RS00375	COG1098	S1 RNA binding domain
GII81_RS00390	COG2208	phosphoserine phosphatase activity
GII81_RS00395	COG2304	oxidoreductase activity
GII81_RS00400	COG0515	serine threonine protein kinase
GII81_RS00405	COG0037	tRNA processing
GII81_RS00410	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GII81_RS00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GII81_RS00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GII81_RS00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GII81_RS00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GII81_RS00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GII81_RS00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GII81_RS00445	COG0512	Glutamine amidotransferase of anthranilate synthase
GII81_RS00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII81_RS00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GII81_RS00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GII81_RS00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GII81_RS00470	COG1396	sequence-specific DNA binding
GII81_RS00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GII81_RS00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GII81_RS00560	COG4463	regulation of RNA biosynthetic process
GII81_RS00565	COG3880	PFAM UvrB UvrC protein
GII81_RS00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
GII81_RS00575	COG0542	response to heat
GII81_RS00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GII81_RS00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
GII81_RS00590	COG4956	integral membrane protein (PIN domain superfamily)
GII81_RS00595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GII81_RS00600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GII81_RS00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GII81_RS00610	COG1045	serine acetyltransferase
GII81_RS00615	COG0215	cysteine-tRNA ligase activity
GII81_RS00620	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GII81_RS00625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GII81_RS00630	COG3688	RNA-binding protein containing a PIN domain
GII81_RS00635	COG1595	DNA-templated transcription, initiation
GII81_RS00645	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GII81_RS00650	COG0250	Participates in transcription elongation, termination and antitermination
GII81_RS00660	COG0081	regulation of translation
GII81_RS00665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GII81_RS00675	COG2813	Specifically methylates the guanine in position
GII81_RS00680	COG0085	RNA polymerase activity
GII81_RS00685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GII81_RS00690	COG1358	cellular component organization or biogenesis
GII81_RS00695	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GII81_RS00700	COG0049	tRNA binding
GII81_RS00705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GII81_RS00710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GII81_RS00715	COG0596	Alpha beta hydrolase
GII81_RS00725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GII81_RS00730	COG0088	Forms part of the polypeptide exit tunnel
GII81_RS00740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GII81_RS00760	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GII81_RS00770	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GII81_RS00775	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GII81_RS00785	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GII81_RS00795	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GII81_RS00800	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GII81_RS00805	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GII81_RS00810	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GII81_RS00820	COG0200	Binds to the 23S rRNA
GII81_RS00825	COG0201	protein transport
GII81_RS00830	COG0563	adenylate kinase activity
GII81_RS00835	COG0024	Methionine aminopeptidase
GII81_RS00840	COG2163	COG2163 Ribosomal protein L14E L6E L27E
GII81_RS00850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GII81_RS00855	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GII81_RS00860	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GII81_RS00865	COG0202	RNA polymerase activity
GII81_RS00870	COG0203	ribosomal protein L17
GII81_RS00875	COG1122	ATPase activity
GII81_RS00880	COG1122	ATPase activity
GII81_RS00885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GII81_RS00890	COG0101	tRNA pseudouridine synthase activity
GII81_RS00895	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GII81_RS00900	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GII81_RS00905	COG2226	methyltransferase
GII81_RS00915	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII81_RS00920	COG0489	protein tyrosine kinase activity
GII81_RS00930	COG2194	sulfuric ester hydrolase activity
GII81_RS00935	COG0726	polysaccharide deacetylase
GII81_RS01015	COG0659	secondary active sulfate transmembrane transporter activity
GII81_RS01020	COG0385	Bile acid
GII81_RS01025	COG2819	hydrolase of the alpha beta superfamily
GII81_RS01030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII81_RS01035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII81_RS01040	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII81_RS01045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII81_RS01045	COG2207	Transcriptional regulator
GII81_RS01050	COG3876	Protein conserved in bacteria
GII81_RS01055	COG1472	Belongs to the glycosyl hydrolase 3 family
GII81_RS01060	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GII81_RS01065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII81_RS01065	COG1263	PTS System
GII81_RS01070	COG1737	Transcriptional regulator
GII81_RS01075	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GII81_RS01080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII81_RS01085	COG1683	Conserved Protein
GII81_RS01115	COG1595	DNA-templated transcription, initiation
GII81_RS01120	COG5662	AntiSigma factor
GII81_RS01125	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GII81_RS01130	COG4856	YbbR-like protein
GII81_RS01135	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GII81_RS01145	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GII81_RS01155	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GII81_RS01160	COG2169	Transcriptional regulator
GII81_RS01165	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GII81_RS01170	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GII81_RS01175	COG3002	Belongs to the UPF0753 family
GII81_RS01180	COG0288	reversible hydration of carbon dioxide
GII81_RS01190	COG5609	conserved protein (DUF2294)
GII81_RS01195	COG0640	Transcriptional regulator
GII81_RS01200	COG2814	Major facilitator Superfamily
GII81_RS01215	COG1404	Belongs to the peptidase S8 family
GII81_RS01235	COG1132	(ABC) transporter
GII81_RS01240	COG0596	Alpha beta hydrolase
GII81_RS01245	COG0745	RESPONSE REGULATOR receiver
GII81_RS01250	COG0642	Histidine kinase
GII81_RS01260	COG0515	serine threonine protein kinase
GII81_RS01275	COG1113	amino acid transport
GII81_RS01290	COG2602	Beta-lactamase
GII81_RS01295	COG2124	cytochrome p450
GII81_RS01305	COG0531	amino acid
GII81_RS01310	COG0584	glycerophosphoryl diester phosphodiesterase
GII81_RS01315	COG2271	Major facilitator Superfamily
GII81_RS01325	COG1846	Transcriptional regulator
GII81_RS01325	COG0456	acetyltransferase
GII81_RS01330	COG2271	Major facilitator Superfamily
GII81_RS01340	COG3409	Peptidoglycan-binding domain 1 protein
GII81_RS01345	COG0697	spore germination
GII81_RS01350	COG1917	Cupin 2, conserved barrel domain protein
GII81_RS01350	COG2207	Transcriptional regulator
GII81_RS01355	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GII81_RS01360	COG3591	Belongs to the peptidase S1B family
GII81_RS01370	COG0596	Alpha beta hydrolase
GII81_RS01375	COG1183	phosphatidylcholine synthase activity
GII81_RS01380	COG0586	Pfam SNARE associated Golgi protein
GII81_RS01385	COG0688	phosphatidylethanolamine metabolic process
GII81_RS01395	COG2312	Erythromycin esterase
GII81_RS01400	COG1054	Belongs to the UPF0176 family
GII81_RS01405	COG1301	dicarboxylic acid transport
GII81_RS01410	COG2190	(PTS) system
GII81_RS01410	COG1263	PTS System
GII81_RS01410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII81_RS01415	COG0363	glucosamine-6-phosphate deaminase activity
GII81_RS01420	COG2188	Transcriptional regulator
GII81_RS01430	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII81_RS01435	COG0833	amino acid
GII81_RS01440	COG2040	homocysteine
GII81_RS01450	COG1115	amino acid carrier protein
GII81_RS01455	COG2066	Belongs to the glutaminase family
GII81_RS01460	COG4191	Histidine kinase
GII81_RS01465	COG0784	Response regulator, receiver
GII81_RS01470	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GII81_RS01475	COG1012	belongs to the aldehyde dehydrogenase family
GII81_RS01480	COG2271	Major facilitator Superfamily
GII81_RS01485	COG4948	Mandelate Racemase Muconate Lactonizing
GII81_RS01490	COG2186	Transcriptional regulator
GII81_RS01495	COG2721	sulfolactate sulfo-lyase activity
GII81_RS01500	COG3173	Aminoglycoside phosphotransferase
GII81_RS01515	COG0745	RESPONSE REGULATOR receiver
GII81_RS01520	COG2205	protein histidine kinase activity
GII81_RS01525	COG1131	(ABC) transporter
GII81_RS01545	COG3773	Cell wall hydrolase
GII81_RS01550	COG2304	oxidoreductase activity
GII81_RS01560	COG3540	Alkaline phosphatase
GII81_RS01565	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GII81_RS01570	COG0805	protein transport
GII81_RS01575	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GII81_RS01580	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GII81_RS01585	COG0477	Major facilitator Superfamily
GII81_RS01590	COG1309	transcriptional regulator
GII81_RS01595	COG0252	asparaginase activity
GII81_RS01600	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GII81_RS01605	COG1714	RDD family
GII81_RS01610	COG1405	negative regulation of cell septum assembly
GII81_RS01610	COG3012	SEC-C Motif Domain Protein
GII81_RS01615	COG3290	protein histidine kinase activity
GII81_RS01620	COG3279	Response regulator of the LytR AlgR family
GII81_RS01625	COG4555	ABC transporter
GII81_RS01630	COG1668	transmembrane transport
GII81_RS01635	COG0667	Aldo Keto reductase
GII81_RS01650	COG1595	DNA-templated transcription, initiation
GII81_RS01655	COG1595	DNA-templated transcription, initiation
GII81_RS01660	COG1876	peptidase activity
GII81_RS01665	COG0457	Tetratricopeptide repeat
GII81_RS01670	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_RS01675	COG0366	Alpha amylase catalytic
GII81_RS01680	COG0803	Belongs to the bacterial solute-binding protein 9 family
GII81_RS01685	COG1121	(ABC) transporter
GII81_RS01690	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GII81_RS01695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII81_RS01700	COG2310	stress, protein
GII81_RS01705	COG2310	stress, protein
GII81_RS01710	COG2310	stress, protein
GII81_RS01715	COG0861	Integral membrane protein TerC family
GII81_RS01725	COG3853	Toxic anion resistance protein (TelA)
GII81_RS01730	COG0477	Major facilitator Superfamily
GII81_RS01735	COG2814	Major facilitator Superfamily
GII81_RS01740	COG0640	Transcriptional regulator
GII81_RS01745	COG4175	Glycine betaine
GII81_RS01745	COG0517	IMP dehydrogenase activity
GII81_RS01750	COG4176	ABC-type proline glycine betaine transport system permease component
GII81_RS01755	COG2113	Glycine betaine
GII81_RS01760	COG1473	amidohydrolase
GII81_RS01765	COG1288	antiporter activity
GII81_RS01775	COG0366	Alpha amylase catalytic
GII81_RS01780	COG0039	L-malate dehydrogenase activity
GII81_RS01785	COG1620	l-lactate permease
GII81_RS01790	COG2814	Major facilitator Superfamily
GII81_RS01795	COG1846	Transcriptional regulator
GII81_RS01800	COG1280	lysine exporter protein (LysE YggA)
GII81_RS01805	COG3403	YqcI/YcgG family
GII81_RS01810	COG1113	amino acid transport
GII81_RS01815	COG3665	Urea carboxylase-associated protein
GII81_RS01820	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GII81_RS01825	COG1660	Displays ATPase and GTPase activities
GII81_RS01830	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GII81_RS01835	COG2226	methyltransferase
GII81_RS01840	COG0583	DNA-binding transcription factor activity
GII81_RS01845	COG3458	cephalosporin-C deacetylase activity
GII81_RS01850	COG3541	Predicted nucleotidyltransferase
GII81_RS01855	COG0506	proline dehydrogenase activity
GII81_RS01860	COG1012	belongs to the aldehyde dehydrogenase family
GII81_RS01865	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII81_RS01870	COG2508	Transcriptional regulator
GII81_RS01875	COG3689	TIGRFAM TIGR03943 family protein
GII81_RS01880	COG0701	Predicted permease
GII81_RS01885	COG2267	carboxylic ester hydrolase activity
GII81_RS01890	COG0492	ferredoxin-NADP+ reductase activity
GII81_RS01895	COG1587	Uroporphyrinogen-III synthase
GII81_RS01895	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GII81_RS01900	COG2146	nitrite reductase [NAD(P)H] activity
GII81_RS01905	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GII81_RS01910	COG0243	molybdopterin cofactor binding
GII81_RS01915	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GII81_RS01920	COG2223	nitrite transmembrane transporter activity
GII81_RS01925	COG1469	GTP cyclohydrolase I activity
GII81_RS01930	COG1376	ErfK ybiS ycfS ynhG family protein
GII81_RS01940	COG0523	cobalamin synthesis protein
GII81_RS01945	COG0765	amino acid transport
GII81_RS01950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII81_RS01960	COG1714	RDD family
GII81_RS01970	COG2723	6-phospho-beta-galactosidase activity
GII81_RS01980	COG3209	COG3209 Rhs family protein
GII81_RS01985	COG0840	transmembrane signaling receptor activity
GII81_RS01985	COG3290	protein histidine kinase activity
GII81_RS01990	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GII81_RS01995	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
GII81_RS02000	COG1733	regulation of RNA biosynthetic process
GII81_RS02005	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII81_RS02010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII81_RS02015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII81_RS02020	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
GII81_RS02025	COG2814	Major facilitator Superfamily
GII81_RS02035	COG0697	spore germination
GII81_RS02050	COG2364	Membrane
GII81_RS02055	COG1126	abc transporter atp-binding protein
GII81_RS02060	COG0765	amino acid transport
GII81_RS02065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII81_RS02070	COG0583	DNA-binding transcription factor activity
GII81_RS02075	COG0163	prenyltransferase activity
GII81_RS02080	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GII81_RS02095	COG0596	Alpha beta hydrolase
GII81_RS02100	COG3104	oligopeptide transport
GII81_RS02105	COG5434	Belongs to the glycosyl hydrolase 28 family
GII81_RS02115	COG0697	spore germination
GII81_RS02125	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GII81_RS02130	COG1136	(ABC) transporter
GII81_RS02135	COG0577	efflux transmembrane transporter activity
GII81_RS02140	COG0745	RESPONSE REGULATOR receiver
GII81_RS02145	COG3850	Histidine kinase
GII81_RS02145	COG5002	protein histidine kinase activity
GII81_RS02150	COG0457	Tetratricopeptide repeat
GII81_RS02170	COG0527	aspartate kinase activity
GII81_RS02175	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII81_RS02180	COG4605	iron ion homeostasis
GII81_RS02185	COG4604	ABC transporter, ATP-binding protein
GII81_RS02190	COG4607	ABC-type enterochelin transport system periplasmic component
GII81_RS02195	COG2814	Major facilitator Superfamily
GII81_RS02200	COG1309	transcriptional regulator
GII81_RS02205	COG0778	Nitroreductase
GII81_RS02210	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GII81_RS02215	COG0640	Transcriptional regulator
GII81_RS02220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII81_RS02225	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GII81_RS02230	COG1012	belongs to the aldehyde dehydrogenase family
GII81_RS02235	COG4975	Glucose uptake
GII81_RS02240	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_RS02245	COG4549	nuclear export factor GLE1
GII81_RS02250	COG2372	response to copper ion
GII81_RS02250	COG1276	copper resistance
GII81_RS02255	COG1349	DNA-binding transcription factor activity
GII81_RS02265	COG2213	PTS system mannitol-specific
GII81_RS02270	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII81_RS02275	COG0246	Mannitol dehydrogenase
GII81_RS02280	COG0473	3-isopropylmalate dehydrogenase activity
GII81_RS02285	COG0681	Belongs to the peptidase S26 family
GII81_RS02290	COG0412	Dienelactone hydrolase
GII81_RS02295	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GII81_RS02305	COG0561	phosphatase activity
GII81_RS02310	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GII81_RS02315	COG1914	H( )-stimulated, divalent metal cation uptake system
GII81_RS02320	COG4336	lyase activity
GII81_RS02325	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GII81_RS02330	COG1984	allophanate hydrolase subunit 2
GII81_RS02335	COG1414	Transcriptional regulator
GII81_RS02340	COG2755	lipolytic protein G-D-S-L family
GII81_RS02350	COG2329	Antibiotic biosynthesis monooxygenase
GII81_RS02355	COG0768	penicillin binding
GII81_RS02360	COG4989	oxidoreductase activity
GII81_RS02365	COG3711	transcriptional antiterminator
GII81_RS02370	COG0318	PFAM AMP-dependent synthetase and ligase
GII81_RS02375	COG2226	methyltransferase
GII81_RS02380	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_RS02385	COG1917	Cupin 2, conserved barrel domain protein
GII81_RS02390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII81_RS02395	COG3871	stress protein (general stress protein 26)
GII81_RS02405	COG2814	Major facilitator Superfamily
GII81_RS02410	COG1522	sequence-specific DNA binding
GII81_RS02415	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GII81_RS02415	COG0551	DNA topoisomerase type I activity
GII81_RS02420	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GII81_RS02425	COG3706	GGDEF domain
GII81_RS02430	COG5298	Protein conserved in bacteria
GII81_RS02435	COG1215	transferase activity, transferring glycosyl groups
GII81_RS02445	COG0531	amino acid
GII81_RS02450	COG0494	nUDIX hydrolase
GII81_RS02455	COG0028	Belongs to the TPP enzyme family
GII81_RS02470	COG1914	H( )-stimulated, divalent metal cation uptake system
GII81_RS02475	COG2261	transglycosylase associated protein
GII81_RS02480	COG4876	unkown
GII81_RS02485	COG2217	Heavy metal translocating P-type atpase
GII81_RS02490	COG3729	General stress protein
GII81_RS02495	COG0662	Cupin 2, conserved barrel domain protein
GII81_RS02500	COG2329	Antibiotic biosynthesis monooxygenase
GII81_RS02505	COG3546	catalase activity
GII81_RS02510	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GII81_RS02515	COG3290	protein histidine kinase activity
GII81_RS02520	COG4565	transcriptional regulatory protein
GII81_RS02525	COG1301	dicarboxylic acid transport
GII81_RS02530	COG0628	permease
GII81_RS02535	COG1131	(ABC) transporter
GII81_RS02540	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GII81_RS02550	COG1960	acyl-CoA dehydrogenase activity
GII81_RS02565	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GII81_RS02570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII81_RS02575	COG1181	Belongs to the D-alanine--D-alanine ligase family
GII81_RS02580	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GII81_RS02585	COG0513	Belongs to the DEAD box helicase family
GII81_RS02590	COG3402	PFAM membrane-flanked domain
GII81_RS02595	COG3428	Bacterial PH domain
GII81_RS02600	COG0705	Rhomboid family
GII81_RS02605	COG0736	holo-[acyl-carrier-protein] synthase activity
GII81_RS02610	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GII81_RS02615	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GII81_RS02620	COG0864	Transcriptional regulator
GII81_RS02625	COG2337	Toxic component of a toxin-antitoxin (TA) module
GII81_RS02630	COG1366	Belongs to the anti-sigma-factor antagonist family
GII81_RS02635	COG1366	Belongs to the anti-sigma-factor antagonist family
GII81_RS02640	COG2172	sigma factor antagonist activity
GII81_RS02645	COG2208	phosphoserine phosphatase activity
GII81_RS02650	COG1366	Belongs to the anti-sigma-factor antagonist family
GII81_RS02655	COG2172	sigma factor antagonist activity
GII81_RS02660	COG1191	sigma factor activity
GII81_RS02665	COG2208	phosphoserine phosphatase activity
GII81_RS02670	COG2183	response to ionizing radiation
GII81_RS02680	COG3091	SprT-like family
GII81_RS02720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII81_RS02765	COG1476	TRANSCRIPTIONal
GII81_RS02785	COG0693	protein deglycase activity
GII81_RS02790	COG1278	Cold shock
GII81_RS02795	COG1329	Transcriptional regulator
GII81_RS02800	COG0697	spore germination
GII81_RS02805	COG2207	Transcriptional regulator
GII81_RS02805	COG1917	Cupin 2, conserved barrel domain protein
GII81_RS02810	COG0697	spore germination
GII81_RS02815	COG3708	Transcriptional regulator
GII81_RS02815	COG2207	Transcriptional regulator
GII81_RS02820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII81_RS02825	COG0477	Major facilitator Superfamily
GII81_RS02835	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
GII81_RS02870	COG1309	transcriptional regulator
GII81_RS02875	COG0697	spore germination
GII81_RS02880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII81_RS02885	COG2030	dehydratase
GII81_RS02890	COG3545	Serine hydrolase
GII81_RS02895	COG1733	regulation of RNA biosynthetic process
GII81_RS02900	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII81_RS02905	COG2814	Major facilitator Superfamily
GII81_RS02910	COG1309	transcriptional regulator
GII81_RS02920	COG0640	Transcriptional regulator
GII81_RS02925	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GII81_RS02935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII81_RS02940	COG0697	spore germination
GII81_RS02945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII81_RS02950	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GII81_RS02955	COG0640	Transcriptional regulator
GII81_RS02960	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GII81_RS02975	COG4585	Histidine kinase
GII81_RS02980	COG2197	response regulator
GII81_RS02985	COG2409	Drug exporters of the RND superfamily
GII81_RS02990	COG0596	Alpha beta hydrolase
GII81_RS02995	COG1811	Na channel or pump
GII81_RS03000	COG0789	Transcriptional regulator
GII81_RS03000	COG4978	Transcriptional regulator
GII81_RS03005	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GII81_RS03010	COG0778	Nitroreductase
GII81_RS03015	COG0346	lactoylglutathione lyase activity
GII81_RS03020	COG2259	Doxx family
GII81_RS03025	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII81_RS03040	COG2323	membrane
GII81_RS03045	COG2323	membrane
GII81_RS03050	COG0071	Belongs to the small heat shock protein (HSP20) family
GII81_RS03065	COG1309	transcriptional regulator
GII81_RS03075	COG0456	acetyltransferase
GII81_RS03085	COG0673	inositol 2-dehydrogenase activity
GII81_RS03090	COG1609	Transcriptional regulator
GII81_RS03095	COG2814	Major facilitator Superfamily
GII81_RS03100	COG1082	Xylose isomerase domain protein TIM barrel
GII81_RS03105	COG0488	(ABC) transporter
GII81_RS03110	COG1113	amino acid transport
GII81_RS03115	COG2318	DinB family
GII81_RS03120	COG1846	Transcriptional regulator
GII81_RS03125	COG1033	growth of symbiont in host cell
GII81_RS03125	COG2409	Drug exporters of the RND superfamily
GII81_RS03130	COG0778	Nitroreductase
GII81_RS03135	COG1846	Transcriptional regulator
GII81_RS03140	COG2814	Major facilitator Superfamily
GII81_RS03145	COG0730	response to heat
GII81_RS03150	COG1802	Transcriptional regulator
GII81_RS03155	COG1388	LysM domain
GII81_RS03155	COG3858	chitin binding
GII81_RS03160	COG1819	glycosyl
GII81_RS03170	COG1785	Belongs to the alkaline phosphatase family
GII81_RS03175	COG5646	InterPro IPR014922
GII81_RS03185	COG0454	-acetyltransferase
GII81_RS03190	COG1078	dGTPase activity
GII81_RS03195	COG1388	LysM domain
GII81_RS03200	COG2814	Major facilitator Superfamily
GII81_RS03205	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII81_RS03210	COG1447	Phosphotransferase system cellobiose-specific component IIA
GII81_RS03215	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII81_RS03220	COG2723	6-phospho-beta-galactosidase activity
GII81_RS03225	COG2188	Transcriptional regulator
GII81_RS03230	COG1940	carbohydrate kinase activity
GII81_RS03235	COG1482	cell wall glycoprotein biosynthetic process
GII81_RS03240	COG4124	Belongs to the glycosyl hydrolase 26 family
GII81_RS03285	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GII81_RS03290	COG0802	atpase or kinase
GII81_RS03295	COG1214	PFAM Peptidase M22, glycoprotease
GII81_RS03300	COG0456	acetyltransferase
GII81_RS03305	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GII81_RS03310	COG0488	(ABC) transporter
GII81_RS03315	COG0315	cyclic pyranopterin monophosphate synthase activity
GII81_RS03320	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GII81_RS03325	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GII81_RS03330	COG0805	protein transport
GII81_RS03340	COG1266	CAAX protease self-immunity
GII81_RS03350	COG0459	protein refolding
GII81_RS03360	COG1073	alpha beta
GII81_RS03365	COG0457	Tetratricopeptide repeat
GII81_RS03370	COG1063	alcohol dehydrogenase
GII81_RS03375	COG2211	Major facilitator Superfamily
GII81_RS03380	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII81_RS03385	COG1842	Phage shock protein A
GII81_RS03390	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GII81_RS03395	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GII81_RS03400	COG4260	virion core protein, lumpy skin disease virus
GII81_RS03410	COG2814	Major facilitator Superfamily
GII81_RS03415	COG1063	alcohol dehydrogenase
GII81_RS03420	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GII81_RS03425	COG0823	Involved in the tonB-independent uptake of proteins
GII81_RS03440	COG2267	carboxylic ester hydrolase activity
GII81_RS03450	COG2132	Multicopper oxidase
GII81_RS03455	COG1113	amino acid transport
GII81_RS03465	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GII81_RS03470	COG0714	Associated with various cellular activities
GII81_RS03475	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
GII81_RS03480	COG1305	Transglutaminase-like
GII81_RS03485	COG0519	Catalyzes the synthesis of GMP from XMP
GII81_RS03485	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GII81_RS03490	COG2252	PERMEase
GII81_RS03495	COG3064	Membrane
GII81_RS03505	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
GII81_RS03515	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GII81_RS03520	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GII81_RS03525	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GII81_RS03530	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GII81_RS03535	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GII81_RS03540	COG0047	phosphoribosylformylglycinamidine synthase activity
GII81_RS03545	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GII81_RS03550	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GII81_RS03555	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GII81_RS03560	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GII81_RS03565	COG0138	bifunctional purine biosynthesis protein purh
GII81_RS03570	COG0151	Belongs to the GarS family
GII81_RS03575	COG1522	sequence-specific DNA binding
GII81_RS03580	COG0531	amino acid
GII81_RS03590	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GII81_RS03595	COG1470	cell adhesion involved in biofilm formation
GII81_RS03600	COG4496	protein, YerC YecD
GII81_RS03605	COG0069	glutamate synthase activity
GII81_RS03610	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
GII81_RS03615	COG0210	DNA helicase
GII81_RS03620	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GII81_RS03625	COG4851	CamS sex pheromone cAM373 precursor
GII81_RS03630	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII81_RS03635	COG1285	pathogenesis
GII81_RS03640	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII81_RS03645	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GII81_RS03650	COG0154	amidase activity
GII81_RS03655	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GII81_RS03660	COG1309	transcriptional regulator
GII81_RS03665	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GII81_RS03670	COG1597	lipid kinase activity
GII81_RS03675	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GII81_RS03705	COG5444	nuclease activity
GII81_RS03715	COG3586	endonuclease activity
GII81_RS03725	COG0457	Tetratricopeptide repeat
GII81_RS03735	COG0217	transcriptional regulatory protein
GII81_RS03745	COG1309	transcriptional regulator
GII81_RS03750	COG3631	Ketosteroid isomerase-related protein
GII81_RS03755	COG0702	epimerase
GII81_RS03770	COG3546	catalase activity
GII81_RS03775	COG0454	-acetyltransferase
GII81_RS03785	COG5578	integral membrane protein
GII81_RS03790	COG2972	Histidine kinase
GII81_RS03795	COG2207	Transcriptional regulator
GII81_RS03795	COG4753	response regulator
GII81_RS03800	COG1653	transport
GII81_RS03805	COG1175	transmembrane transport
GII81_RS03810	COG0395	ABC-type sugar transport system, permease component
GII81_RS03815	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GII81_RS03820	COG2207	Transcriptional regulator
GII81_RS03825	COG2755	lipolytic protein G-D-S-L family
GII81_RS03835	COG5578	integral membrane protein
GII81_RS03840	COG3401	FG-GAP repeat protein
GII81_RS03845	COG3401	FG-GAP repeat protein
GII81_RS03850	COG2755	lipolytic protein G-D-S-L family
GII81_RS03855	COG1874	Beta-galactosidase
GII81_RS03865	COG1653	transport
GII81_RS03870	COG4209	transmembrane transport
GII81_RS03875	COG0395	ABC-type sugar transport system, permease component
GII81_RS03880	COG1486	melibiose metabolic process
GII81_RS03885	COG2323	membrane
GII81_RS03890	COG2329	Antibiotic biosynthesis monooxygenase
GII81_RS03895	COG0346	lactoylglutathione lyase activity
GII81_RS03910	COG5583	Uncharacterized small protein (DUF2292)
GII81_RS03915	COG0670	Belongs to the BI1 family
GII81_RS03920	COG0697	spore germination
GII81_RS03925	COG1846	Transcriptional regulator
GII81_RS03930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GII81_RS03945	COG2124	cytochrome p450
GII81_RS03945	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GII81_RS03950	COG1368	sulfuric ester hydrolase activity
GII81_RS03955	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GII81_RS03960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII81_RS03965	COG1442	glycosyl transferase family 8
GII81_RS03970	COG1216	Glycosyl transferase, family 2
GII81_RS03975	COG1442	glycosyl transferase family 8
GII81_RS03980	COG2223	nitrite transmembrane transporter activity
GII81_RS03985	COG1011	Hydrolase
GII81_RS03990	COG0531	amino acid
GII81_RS03995	COG1012	belongs to the aldehyde dehydrogenase family
GII81_RS04000	COG0840	transmembrane signaling receptor activity
GII81_RS04005	COG0488	(ABC) transporter
GII81_RS04015	COG0789	Transcriptional regulator
GII81_RS04020	COG2814	Major facilitator Superfamily
GII81_RS04030	COG0488	(ABC) transporter
GII81_RS04035	COG0513	Belongs to the DEAD box helicase family
GII81_RS04040	COG0456	acetyltransferase
GII81_RS04045	COG2130	NADP-dependent
GII81_RS04050	COG2211	Major facilitator Superfamily
GII81_RS04055	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GII81_RS04060	COG1120	ATPase activity
GII81_RS04065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII81_RS04070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII81_RS04075	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GII81_RS04090	COG3866	Pectate lyase
GII81_RS04095	COG0471	metal ion transport
GII81_RS04100	COG3290	protein histidine kinase activity
GII81_RS04105	COG4565	transcriptional regulatory protein
GII81_RS04110	COG3181	Tripartite tricarboxylate transporter family receptor
GII81_RS04115	COG2851	Citrate transporter
GII81_RS04120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII81_RS04125	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
GII81_RS04130	COG1254	Belongs to the acylphosphatase family
GII81_RS04135	COG2258	MOSC domain
GII81_RS04155	COG0024	Methionine aminopeptidase
GII81_RS04160	COG1263	PTS System
GII81_RS04160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII81_RS04165	COG1368	sulfuric ester hydrolase activity
GII81_RS04180	COG1115	amino acid carrier protein
GII81_RS04185	COG0531	amino acid
GII81_RS04200	COG0697	spore germination
GII81_RS04205	COG1263	PTS System
GII81_RS04205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII81_RS04210	COG0366	Alpha amylase catalytic
GII81_RS04215	COG2188	Transcriptional regulator
GII81_RS04220	COG0778	Nitroreductase
GII81_RS04225	COG0737	Belongs to the 5'-nucleotidase family
GII81_RS04230	COG0693	protein deglycase activity
GII81_RS04235	COG2814	Major facilitator Superfamily
GII81_RS04240	COG4840	Belongs to the UPF0435 family
GII81_RS04245	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GII81_RS04250	COG4980	gas vesicle protein
GII81_RS04255	COG1295	ribonuclease BN
GII81_RS04260	COG0477	Major facilitator Superfamily
GII81_RS04265	COG0387	Pfam Sodium calcium exchanger
GII81_RS04275	COG0668	transmembrane transport
GII81_RS04280	COG0535	radical SAM domain protein
GII81_RS04290	COG0726	polysaccharide deacetylase
GII81_RS04295	COG2084	Dehydrogenase
GII81_RS04300	COG0598	Magnesium transport protein CorA
GII81_RS04305	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GII81_RS04310	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GII81_RS04320	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GII81_RS04325	COG4637	Psort location Cytoplasmic, score
GII81_RS04330	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GII81_RS04335	COG0022	dehydrogenase e1 component
GII81_RS04340	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII81_RS04345	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GII81_RS04350	COG3284	Transcriptional regulator
GII81_RS04360	COG1742	UPF0060 membrane protein
GII81_RS04385	COG4842	Belongs to the WXG100 family
GII81_RS04390	COG1486	melibiose metabolic process
GII81_RS04395	COG1737	Transcriptional regulator
GII81_RS04400	COG1263	PTS System
GII81_RS04400	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII81_RS04405	COG1132	(ABC) transporter
GII81_RS04410	COG1132	(ABC) transporter
GII81_RS04415	COG2259	Doxx family
GII81_RS04420	COG2514	catechol 2,3-dioxygenase activity
GII81_RS04425	COG4585	Histidine kinase
GII81_RS04430	COG2197	response regulator
GII81_RS04435	COG1131	(ABC) transporter
GII81_RS04440	COG1511	domain protein
GII81_RS04440	COG0842	Transport permease protein
GII81_RS04445	COG0842	Transport permease protein
GII81_RS04450	COG1695	Transcriptional regulator
GII81_RS04455	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GII81_RS04460	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
GII81_RS04465	COG2318	DinB family
GII81_RS04470	COG2814	Major facilitator Superfamily
GII81_RS04475	COG1846	Transcriptional regulator
GII81_RS04480	COG0392	lysyltransferase activity
GII81_RS04480	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GII81_RS04485	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII81_RS04490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII81_RS04495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII81_RS04500	COG0384	phenazine biosynthesis protein PhzF
GII81_RS04505	COG0778	Nitroreductase
GII81_RS04520	COG1090	epimerase
GII81_RS04525	COG2137	regulation of response to DNA damage stimulus
GII81_RS04535	COG2814	Major facilitator Superfamily
GII81_RS04550	COG3103	Sh3 type 3 domain protein
GII81_RS04555	COG5658	integral membrane protein
GII81_RS04560	COG0596	Alpha beta hydrolase
GII81_RS04565	COG0463	Glycosyl transferase, family 2
GII81_RS04570	COG4485	Bacterial membrane protein, YfhO
GII81_RS04575	COG1988	membrane-bound metal-dependent
GII81_RS04580	COG1194	a g-specific adenine glycosylase
GII81_RS04590	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_RS04605	COG3557	Belongs to the UPF0374 family
GII81_RS04610	COG1132	(ABC) transporter
GII81_RS04615	COG4129	membrane
GII81_RS04620	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GII81_RS04625	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GII81_RS04630	COG0735	belongs to the Fur family
GII81_RS04740	COG4326	sporulation control protein
GII81_RS04750	COG5577	PFAM Coat F domain
GII81_RS04755	COG3340	Belongs to the peptidase S51 family
GII81_RS04760	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GII81_RS04765	COG0277	FAD linked oxidase domain protein
GII81_RS04775	COG0753	catalase activity
GII81_RS04780	COG1116	anion transmembrane transporter activity
GII81_RS04785	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GII81_RS04790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GII81_RS04795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII81_RS04805	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GII81_RS04815	COG1476	TRANSCRIPTIONal
GII81_RS04825	COG3382	B3 4 domain protein
GII81_RS04830	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GII81_RS04840	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GII81_RS04845	COG0789	Transcriptional regulator
GII81_RS04850	COG1664	Polymer-forming cytoskeletal
GII81_RS04855	COG1664	Polymer-forming cytoskeletal
GII81_RS04860	COG2766	serine protein kinase
GII81_RS04865	COG2718	Belongs to the UPF0229 family
GII81_RS04870	COG1846	Transcriptional regulator
GII81_RS04875	COG1566	PFAM secretion protein HlyD family protein
GII81_RS04880	COG2814	Major facilitator Superfamily
GII81_RS04885	COG0655	NAD(P)H dehydrogenase (quinone) activity
GII81_RS04905	COG1725	Transcriptional regulator
GII81_RS04910	COG1131	(ABC) transporter
GII81_RS04915	COG1131	(ABC) transporter
GII81_RS04920	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GII81_RS04925	COG1278	Cold shock
GII81_RS04930	COG1464	Belongs to the NlpA lipoprotein family
GII81_RS04935	COG3706	GGDEF domain
GII81_RS04940	COG1823	symporter activity
GII81_RS04960	COG5577	PFAM Coat F domain
GII81_RS04965	COG4085	toxin activity
GII81_RS04965	COG0737	Belongs to the 5'-nucleotidase family
GII81_RS04965	COG1525	nuclease
GII81_RS04970	COG3764	Sortase (surface protein transpeptidase)
GII81_RS04975	COG0564	pseudouridine synthase activity
GII81_RS04985	COG0517	IMP dehydrogenase activity
GII81_RS04990	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GII81_RS04995	COG3153	acetyltransferase
GII81_RS04995	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GII81_RS05000	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GII81_RS05005	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GII81_RS05010	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GII81_RS05015	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GII81_RS05020	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GII81_RS05025	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GII81_RS05030	COG4585	Histidine kinase
GII81_RS05030	COG2203	Gaf domain
GII81_RS05035	COG2197	response regulator
GII81_RS05040	COG0431	NADPH-dependent FMN reductase
GII81_RS05055	COG0791	NLP P60 protein
GII81_RS05055	COG1388	LysM domain
GII81_RS05060	COG1959	2 iron, 2 sulfur cluster binding
GII81_RS05065	COG0668	transmembrane transport
GII81_RS05070	COG2719	SpoVR family
GII81_RS05075	COG1785	Belongs to the alkaline phosphatase family
GII81_RS05080	COG1388	LysM domain
GII81_RS05080	COG0791	NLP P60 protein
GII81_RS05085	COG0583	DNA-binding transcription factor activity
GII81_RS05090	COG0372	Belongs to the citrate synthase family
GII81_RS05095	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_RS05100	COG0531	amino acid
GII81_RS05105	COG0733	neurotransmitter:sodium symporter activity
GII81_RS05110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII81_RS05115	COG0456	acetyltransferase
GII81_RS05130	COG1595	DNA-templated transcription, initiation
GII81_RS05135	COG0667	Aldo Keto reductase
GII81_RS05140	COG0204	Acyl-transferase
GII81_RS05145	COG1253	flavin adenine dinucleotide binding
GII81_RS05150	COG0789	Transcriptional regulator
GII81_RS05155	COG0436	Aminotransferase
GII81_RS05160	COG1253	flavin adenine dinucleotide binding
GII81_RS05165	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GII81_RS05170	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GII81_RS05175	COG0584	glycerophosphoryl diester phosphodiesterase
GII81_RS05185	COG0668	transmembrane transport
GII81_RS05190	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GII81_RS05195	COG0726	polysaccharide deacetylase
GII81_RS05200	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII81_RS05205	COG1757	Na H antiporter
GII81_RS05210	COG0589	response to stress
GII81_RS05220	COG1132	(ABC) transporter
GII81_RS05225	COG1132	(ABC) transporter
GII81_RS05230	COG0702	epimerase
GII81_RS05250	COG0189	ligase activity
GII81_RS05255	COG0189	ligase activity
GII81_RS05260	COG4399	Belongs to the UPF0754 family
GII81_RS05265	COG3679	Belongs to the UPF0342 family
GII81_RS05270	COG4335	DNA alkylation repair
GII81_RS05275	COG0561	phosphatase activity
GII81_RS05280	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GII81_RS05285	COG0475	glutathione-regulated potassium exporter activity
GII81_RS05290	COG0490	domain, Protein
GII81_RS05300	COG1024	Enoyl-CoA hydratase
GII81_RS05310	COG4152	abc transporter atp-binding protein
GII81_RS05315	COG1668	transmembrane transport
GII81_RS05320	COG0420	3'-5' exonuclease activity
GII81_RS05325	COG4717	serine-type aminopeptidase activity
GII81_RS05330	COG3481	metal-dependent phosphohydrolase, HD sub domain
GII81_RS05340	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GII81_RS05370	COG1846	Transcriptional regulator
GII81_RS05375	COG4980	gas vesicle protein
GII81_RS05390	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GII81_RS05395	COG0537	adenosine 5'-monophosphoramidase activity
GII81_RS05400	COG1131	(ABC) transporter
GII81_RS05405	COG4473	ABC transporter
GII81_RS05415	COG1473	amidohydrolase
GII81_RS05420	COG3069	C4-dicarboxylate transmembrane transporter activity
GII81_RS05430	COG2329	Antibiotic biosynthesis monooxygenase
GII81_RS05435	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII81_RS05440	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GII81_RS05445	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GII81_RS05450	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GII81_RS05455	COG1309	transcriptional regulator
GII81_RS05460	COG1511	domain protein
GII81_RS05465	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GII81_RS05470	COG4377	Putative membrane peptidase family (DUF2324)
GII81_RS05480	COG1363	Peptidase, m42
GII81_RS05485	COG4405	Protein conserved in bacteria
GII81_RS05490	COG1301	dicarboxylic acid transport
GII81_RS05500	COG1234	tRNA 3'-trailer cleavage
GII81_RS05505	COG0095	Lipoate-protein ligase
GII81_RS05510	COG0702	epimerase
GII81_RS05515	COG0318	PFAM AMP-dependent synthetase and ligase
GII81_RS05525	COG0501	Belongs to the peptidase M48B family
GII81_RS05530	COG1404	Belongs to the peptidase S8 family
GII81_RS05535	COG0456	acetyltransferase
GII81_RS05540	COG0604	alcohol dehydrogenase
GII81_RS05545	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GII81_RS05550	COG0406	alpha-ribazole phosphatase activity
GII81_RS05555	COG0183	Belongs to the thiolase family
GII81_RS05560	COG0318	PFAM AMP-dependent synthetase and ligase
GII81_RS05565	COG1268	BioY protein
GII81_RS05570	COG0840	transmembrane signaling receptor activity
GII81_RS05575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GII81_RS05575	COG0723	plastoquinol--plastocyanin reductase activity
GII81_RS05580	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_RS05590	COG4903	ComK protein
GII81_RS05595	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_RS05605	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII81_RS05620	COG0398	Pfam SNARE associated Golgi protein
GII81_RS05625	COG0681	Belongs to the peptidase S26 family
GII81_RS05630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GII81_RS05635	COG1846	Transcriptional regulator
GII81_RS05640	COG0738	Major facilitator superfamily
GII81_RS05645	COG0673	inositol 2-dehydrogenase activity
GII81_RS05650	COG0561	phosphatase activity
GII81_RS05655	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GII81_RS05660	COG1609	Transcriptional regulator
GII81_RS05665	COG3180	Ammonia monooxygenase
GII81_RS05670	COG2814	Major facilitator Superfamily
GII81_RS05670	COG0477	Major facilitator Superfamily
GII81_RS05675	COG4533	DNA binding
GII81_RS05685	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
GII81_RS05690	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GII81_RS05695	COG1074	ATP-dependent DNA helicase activity
GII81_RS05700	COG0420	3'-5' exonuclease activity
GII81_RS05705	COG0419	ATPase involved in DNA repair
GII81_RS05710	COG1403	HNH endonuclease
GII81_RS05750	COG5337	Spore coat protein CotH
GII81_RS05755	COG0179	Fumarylacetoacetate (FAA) hydrolase
GII81_RS05765	COG1404	Belongs to the peptidase S8 family
GII81_RS05775	COG0367	asparagine synthase
GII81_RS05780	COG2318	DinB family
GII81_RS05785	COG1562	ergosterol biosynthetic process
GII81_RS05790	COG0534	Mate efflux family protein
GII81_RS05795	COG1917	Cupin 2, conserved barrel domain protein
GII81_RS05795	COG2207	Transcriptional regulator
GII81_RS05800	COG1609	Transcriptional regulator
GII81_RS05805	COG0673	inositol 2-dehydrogenase activity
GII81_RS05810	COG2318	DinB family
GII81_RS05815	COG1279	arginine transmembrane transporter activity
GII81_RS05820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII81_RS05825	COG1357	PFAM Pentapeptide repeats (8 copies)
GII81_RS05830	COG2267	carboxylic ester hydrolase activity
GII81_RS05835	COG0529	Catalyzes the synthesis of activated sulfate
GII81_RS05840	COG2046	Belongs to the sulfate adenylyltransferase family
GII81_RS05845	COG0175	sulfate reduction
GII81_RS05850	COG2045	Belongs to the ComB family
GII81_RS05855	COG1809	phosphosulfolactate synthase activity
GII81_RS05860	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII81_RS05865	COG4948	Mandelate Racemase Muconate Lactonizing
GII81_RS05870	COG2814	Major facilitator Superfamily
GII81_RS05875	COG0454	-acetyltransferase
GII81_RS05880	COG2153	protein acetylation
GII81_RS05885	COG0646	methionine synthase
GII81_RS05885	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GII81_RS05890	COG1666	GTP binding
GII81_RS05895	COG2996	Protein conserved in bacteria
GII81_RS05915	COG1695	Transcriptional regulator
GII81_RS05930	COG3227	Zinc metalloprotease (Elastase)
GII81_RS05935	COG1307	EDD domain protein, DegV family
GII81_RS05940	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII81_RS05955	COG0561	phosphatase activity
GII81_RS05960	COG1073	alpha beta
GII81_RS05965	COG2151	metal-sulfur cluster biosynthetic enzyme
GII81_RS05975	COG0277	FAD linked oxidase domain protein
GII81_RS05980	COG2271	Major facilitator Superfamily
GII81_RS05985	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GII81_RS05990	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GII81_RS06000	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GII81_RS06005	COG0505	Belongs to the CarA family
GII81_RS06010	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GII81_RS06015	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GII81_RS06030	COG2267	carboxylic ester hydrolase activity
GII81_RS06040	COG1744	ABC transporter substrate-binding protein PnrA-like
GII81_RS06055	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GII81_RS06060	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GII81_RS06065	COG5504	Zn-dependent protease
GII81_RS06070	COG0444	Belongs to the ABC transporter superfamily
GII81_RS06075	COG4608	Belongs to the ABC transporter superfamily
GII81_RS06085	COG0601	transmembrane transport
GII81_RS06090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GII81_RS06100	COG0180	Tryptophanyl-tRNA synthetase
GII81_RS06105	COG4166	transmembrane transport
GII81_RS06110	COG0601	transmembrane transport
GII81_RS06115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GII81_RS06120	COG0444	Belongs to the ABC transporter superfamily
GII81_RS06125	COG4608	Belongs to the ABC transporter superfamily
GII81_RS06130	COG2814	Major facilitator Superfamily
GII81_RS06135	COG0456	acetyltransferase
GII81_RS06140	COG1393	Belongs to the ArsC family
GII81_RS06145	COG0861	Integral membrane protein TerC family
GII81_RS06155	COG4862	establishment of competence for transformation
GII81_RS06165	COG4469	Competence protein
GII81_RS06170	COG1164	Oligoendopeptidase f
GII81_RS06180	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GII81_RS06185	COG2346	COG2346, Truncated hemoglobins
GII81_RS06190	COG0741	lytic transglycosylase activity
GII81_RS06195	COG4116	CYTH
GII81_RS06205	COG2357	RelA SpoT domain protein
GII81_RS06210	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GII81_RS06215	COG0564	pseudouridine synthase activity
GII81_RS06220	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GII81_RS06225	COG0475	glutathione-regulated potassium exporter activity
GII81_RS06225	COG0569	domain protein
GII81_RS06230	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GII81_RS06235	COG0352	thiamine-phosphate diphosphorylase activity
GII81_RS06240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GII81_RS06245	COG2104	thiamine diphosphate biosynthetic process
GII81_RS06250	COG2022	thiamine diphosphate biosynthetic process
GII81_RS06255	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GII81_RS06260	COG0351	phosphomethylpyrimidine kinase
GII81_RS06265	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GII81_RS06320	COG0210	DNA helicase
GII81_RS06330	COG2153	protein acetylation
GII81_RS06335	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GII81_RS06340	COG2382	esterase
GII81_RS06345	COG0626	cystathionine gamma-synthase activity
GII81_RS06350	COG0626	cystathionine gamma-synthase activity
GII81_RS06355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII81_RS06360	COG5505	Protein of unknown function (DUF819)
GII81_RS06385	COG5444	nuclease activity
GII81_RS06430	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GII81_RS06435	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_RS06445	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII81_RS06445	COG3711	transcriptional antiterminator
GII81_RS06450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII81_RS06450	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII81_RS06450	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII81_RS06455	COG1482	cell wall glycoprotein biosynthetic process
GII81_RS06465	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII81_RS06475	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GII81_RS06490	COG0109	protoheme IX farnesyltransferase activity
GII81_RS06500	COG0726	polysaccharide deacetylase
GII81_RS06515	COG5504	Zn-dependent protease
GII81_RS06520	COG2205	protein histidine kinase activity
GII81_RS06530	COG3383	formate dehydrogenase (NAD+) activity
GII81_RS06535	COG2427	Protein of unknown function (DUF1641)
GII81_RS06545	COG1051	belongs to the nudix hydrolase family
GII81_RS06555	COG2124	cytochrome p450
GII81_RS06560	COG1819	glycosyl
GII81_RS06570	COG1587	Uroporphyrinogen-III synthase
GII81_RS06575	COG0390	transport system, permease component
GII81_RS06580	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GII81_RS06585	COG0697	spore germination
GII81_RS06590	COG4297	protein containing double-stranded beta helix domain
GII81_RS06600	COG1252	NADH dehydrogenase
GII81_RS06605	COG1904	glucuronate isomerase
GII81_RS06610	COG2211	Major facilitator Superfamily
GII81_RS06615	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GII81_RS06620	COG1063	alcohol dehydrogenase
GII81_RS06625	COG1312	Catalyzes the dehydration of D-mannonate
GII81_RS06630	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_RS06635	COG2271	Major facilitator Superfamily
GII81_RS06640	COG1609	Transcriptional regulator
GII81_RS06645	COG0246	Mannitol dehydrogenase
GII81_RS06650	COG2721	sulfolactate sulfo-lyase activity
GII81_RS06655	COG0730	response to heat
GII81_RS06660	COG2318	DinB family
GII81_RS06665	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GII81_RS06670	COG0457	Tetratricopeptide repeat
GII81_RS06680	COG2350	Protein conserved in bacteria
GII81_RS06685	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII81_RS06685	COG3409	Peptidoglycan-binding domain 1 protein
GII81_RS06685	COG1388	LysM domain
GII81_RS06695	COG4195	phage-related replication protein
GII81_RS06700	COG3546	catalase activity
GII81_RS06705	COG2856	Zn peptidase
GII81_RS06710	COG1396	sequence-specific DNA binding
GII81_RS06720	COG1522	sequence-specific DNA binding
GII81_RS06725	COG1484	DNA-dependent DNA replication
GII81_RS06745	COG1595	DNA-templated transcription, initiation
GII81_RS06750	COG5484	DNA packaging
GII81_RS06750	COG3728	DNA packaging
GII81_RS06755	COG1783	phage Terminase large subunit
GII81_RS06760	COG5518	Phage portal protein
GII81_RS06765	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GII81_RS06770	COG4653	Phage capsid family
GII81_RS06820	COG5412	phage tail tape measure protein
GII81_RS06820	COG3953	SLT domain
GII81_RS06820	COG5412	phage tail tape measure protein
GII81_RS06820	COG3953	SLT domain
GII81_RS06825	COG1652	LysM domain
GII81_RS06830	COG4193	domain, Protein
GII81_RS06840	COG3628	GPW Gp25 family protein
GII81_RS06845	COG3299	homolog of phage Mu protein gp47
GII81_RS06850	COG3778	Protein conserved in bacteria
GII81_RS06890	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII81_RS06890	COG3409	Peptidoglycan-binding domain 1 protein
GII81_RS06910	COG0306	phosphate transporter
GII81_RS06915	COG1392	Phosphate transport regulator
GII81_RS06920	COG0531	amino acid
GII81_RS06925	COG0346	lactoylglutathione lyase activity
GII81_RS06930	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GII81_RS06935	COG0463	Glycosyl transferase, family 2
GII81_RS06940	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII81_RS06945	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII81_RS06950	COG2362	D-Aminopeptidase
GII81_RS06955	COG0601	transmembrane transport
GII81_RS06960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GII81_RS06965	COG0444	Belongs to the ABC transporter superfamily
GII81_RS06970	COG4166	transmembrane transport
GII81_RS06975	COG1619	proteins homologs of microcin C7 resistance protein MccF
GII81_RS06980	COG4948	Mandelate Racemase Muconate Lactonizing
GII81_RS06985	COG0791	NLP P60 protein
GII81_RS06990	COG4608	Belongs to the ABC transporter superfamily
GII81_RS06995	COG2706	6-phosphogluconolactonase activity
GII81_RS07000	COG1834	amidinotransferase
GII81_RS07005	COG1607	acyl-coa hydrolase
GII81_RS07010	COG1017	nitric oxide dioxygenase activity
GII81_RS07010	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GII81_RS07020	COG2323	membrane
GII81_RS07025	COG2318	DinB family
GII81_RS07030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII81_RS07035	COG2076	Multidrug Resistance protein
GII81_RS07040	COG2076	Multidrug Resistance protein
GII81_RS07045	COG0788	formyltetrahydrofolate deformylase activity
GII81_RS07050	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GII81_RS07055	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GII81_RS07060	COG1764	response to oxidative stress
GII81_RS07065	COG1846	Transcriptional regulator
GII81_RS07070	COG1764	response to oxidative stress
GII81_RS07075	COG0590	tRNA wobble adenosine to inosine editing
GII81_RS07080	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GII81_RS07085	COG1404	Belongs to the peptidase S8 family
GII81_RS07090	COG1366	Belongs to the anti-sigma-factor antagonist family
GII81_RS07095	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GII81_RS07100	COG1122	ATPase activity
GII81_RS07105	COG4721	ABC-type cobalt transport system, permease component
GII81_RS07115	COG0745	RESPONSE REGULATOR receiver
GII81_RS07120	COG5002	protein histidine kinase activity
GII81_RS07120	COG3850	Histidine kinase
GII81_RS07125	COG3212	peptidase
GII81_RS07130	COG3212	peptidase
GII81_RS07140	COG2239	Acts as a magnesium transporter
GII81_RS07145	COG0789	Transcriptional regulator
GII81_RS07160	COG1846	Transcriptional regulator
GII81_RS07165	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GII81_RS07170	COG0726	polysaccharide deacetylase
GII81_RS07175	COG1408	metallophosphoesterase
GII81_RS07185	COG0463	Glycosyl transferase, family 2
GII81_RS07190	COG3285	dna ligase
GII81_RS07190	COG1793	dna ligase
GII81_RS07195	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GII81_RS07200	COG5001	Diguanylate cyclase
GII81_RS07200	COG3300	MHYT domain
GII81_RS07205	COG0586	Pfam SNARE associated Golgi protein
GII81_RS07210	COG0861	Integral membrane protein TerC family
GII81_RS07215	COG1191	sigma factor activity
GII81_RS07235	COG0501	Belongs to the peptidase M48B family
GII81_RS07240	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GII81_RS07255	COG3594	Acyltransferase
GII81_RS07260	COG5002	protein histidine kinase activity
GII81_RS07265	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GII81_RS07275	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GII81_RS07280	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
GII81_RS07285	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GII81_RS07290	COG0436	Aminotransferase
GII81_RS07295	COG1850	ribulose-bisphosphate carboxylase activity
GII81_RS07300	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
GII81_RS07305	COG0235	Class ii aldolase
GII81_RS07310	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
GII81_RS07315	COG3339	Conserved Protein
GII81_RS07330	COG3852	Histidine kinase
GII81_RS07335	COG1846	Transcriptional regulator
GII81_RS07340	COG1360	Flagellar Motor Protein
GII81_RS07345	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GII81_RS07350	COG0542	response to heat
GII81_RS07355	COG3949	Membrane
GII81_RS07360	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GII81_RS07365	COG0720	synthase
GII81_RS07370	COG0602	queuosine metabolic process
GII81_RS07375	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GII81_RS07380	COG1733	regulation of RNA biosynthetic process
GII81_RS07385	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_RS07390	COG4641	Protein conserved in bacteria
GII81_RS07390	COG1388	LysM domain
GII81_RS07395	COG1388	LysM domain
GII81_RS07400	COG3858	chitin binding
GII81_RS07410	COG4873	Protein conserved in bacteria
GII81_RS07420	COG3773	Cell wall hydrolase
GII81_RS07425	COG2244	polysaccharide biosynthetic process
GII81_RS07430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII81_RS07435	COG2217	Heavy metal translocating P-type atpase
GII81_RS07445	COG0006	proline dipeptidase activity
GII81_RS07450	COG1609	Transcriptional regulator
GII81_RS07455	COG3711	transcriptional antiterminator
GII81_RS07460	COG2190	(PTS) system
GII81_RS07460	COG1263	PTS System
GII81_RS07460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII81_RS07465	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII81_RS07470	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GII81_RS07480	COG1533	DNA photolyase activity
GII81_RS07485	COG0456	acetyltransferase
GII81_RS07490	COG0840	transmembrane signaling receptor activity
GII81_RS07495	COG2084	Dehydrogenase
GII81_RS07500	COG2340	Cysteine-rich secretory protein family
GII81_RS07505	COG0768	penicillin binding
GII81_RS07510	COG4191	Histidine kinase
GII81_RS07515	COG0436	Aminotransferase
GII81_RS07525	COG0835	chemotaxis
GII81_RS07525	COG0784	Response regulator, receiver
GII81_RS07535	COG2814	Major facilitator Superfamily
GII81_RS07540	COG1376	ErfK ybiS ycfS ynhG family protein
GII81_RS07545	COG1408	metallophosphoesterase
GII81_RS07550	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_RS07555	COG2200	EAL domain
GII81_RS07560	COG4703	Protein of unknown function (DUF1797)
GII81_RS07565	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
GII81_RS07575	COG0517	IMP dehydrogenase activity
GII81_RS07580	COG0583	DNA-binding transcription factor activity
GII81_RS07585	COG0716	FMN binding
GII81_RS07595	COG0716	FMN binding
GII81_RS07600	COG2171	N-acyltransferase activity
GII81_RS07605	COG1473	amidohydrolase
GII81_RS07615	COG0668	transmembrane transport
GII81_RS07620	COG0450	alkyl hydroperoxide reductase
GII81_RS07625	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII81_RS07640	COG0746	molybdenum cofactor guanylyltransferase activity
GII81_RS07645	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GII81_RS07650	COG0303	'Molybdopterin
GII81_RS07655	COG1763	Mo-molybdopterin cofactor biosynthetic process
GII81_RS07660	COG0314	molybdopterin synthase activity
GII81_RS07665	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GII81_RS07670	COG1132	(ABC) transporter
GII81_RS07675	COG1132	(ABC) transporter
GII81_RS07685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GII81_RS07690	COG1136	(ABC) transporter
GII81_RS07695	COG0577	efflux transmembrane transporter activity
GII81_RS07700	COG1349	DNA-binding transcription factor activity
GII81_RS07705	COG1105	Belongs to the carbohydrate kinase PfkB family
GII81_RS07710	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII81_RS07710	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII81_RS07710	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII81_RS07715	COG0681	Belongs to the peptidase S26 family
GII81_RS07725	COG0488	(ABC) transporter
GII81_RS07730	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GII81_RS07735	COG2309	aminopeptidase activity
GII81_RS07745	COG1077	Cell shape determining protein MreB Mrl
GII81_RS07750	COG2002	toxin-antitoxin pair type II binding
GII81_RS07755	COG3852	Histidine kinase
GII81_RS07760	COG2105	PFAM AIG2 family protein
GII81_RS07760	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
GII81_RS07765	COG0569	domain protein
GII81_RS07770	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GII81_RS07775	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GII81_RS07780	COG5503	Protein of unknown function (DUF1447)
GII81_RS07785	COG0561	phosphatase activity
GII81_RS07790	COG0242	peptide deformylase activity
GII81_RS07800	COG0497	DNA recombination
GII81_RS07805	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GII81_RS07810	COG0022	dehydrogenase e1 component
GII81_RS07815	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII81_RS07820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GII81_RS07825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII81_RS07835	COG1982	Orn Lys Arg decarboxylase major
GII81_RS07840	COG4476	Belongs to the UPF0223 family
GII81_RS07845	COG4493	Belongs to the UPF0637 family
GII81_RS07855	COG0483	inositol monophosphate 1-phosphatase activity
GII81_RS07865	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GII81_RS07885	COG1595	DNA-templated transcription, initiation
GII81_RS07905	COG1217	gtp-binding protein TYPA
GII81_RS07915	COG4896	Protein conserved in bacteria
GII81_RS07925	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GII81_RS07930	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GII81_RS07935	COG2066	Belongs to the glutaminase family
GII81_RS07940	COG4838	Belongs to the UPF0358 family
GII81_RS07945	COG0772	Belongs to the SEDS family
GII81_RS07950	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GII81_RS07955	COG1612	heme a metabolic process
GII81_RS07960	COG0109	protoheme IX farnesyltransferase activity
GII81_RS07965	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GII81_RS07965	COG2010	Cytochrome c
GII81_RS07970	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GII81_RS07975	COG1845	cytochrome c oxidase, subunit III
GII81_RS07980	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GII81_RS07985	COG3336	cytochrome c oxidase
GII81_RS07995	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
GII81_RS08000	COG2340	Cysteine-rich secretory protein family
GII81_RS08015	COG3679	Belongs to the UPF0342 family
GII81_RS08020	COG4471	UPF0298 protein
GII81_RS08025	COG0742	ribosomal rna small subunit methyltransferase
GII81_RS08030	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GII81_RS08035	COG3314	Sporulation integral membrane protein YlbJ
GII81_RS08040	COG1752	Esterase of the alpha-beta hydrolase superfamily
GII81_RS08045	COG3480	Lon protease (S16) C-terminal proteolytic domain
GII81_RS08050	COG1323	Belongs to the UPF0348 family
GII81_RS08060	COG1399	metal-binding, possibly nucleic acid-binding protein
GII81_RS08075	COG0454	-acetyltransferase
GII81_RS08080	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GII81_RS08085	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
GII81_RS08090	COG2001	Belongs to the MraZ family
GII81_RS08095	COG0275	rRNA processing
GII81_RS08100	COG4839	cell division protein FtsL
GII81_RS08105	COG0768	penicillin binding
GII81_RS08110	COG0768	penicillin binding
GII81_RS08115	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GII81_RS08120	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GII81_RS08125	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GII81_RS08130	COG0772	Belongs to the SEDS family
GII81_RS08135	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GII81_RS08140	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GII81_RS08145	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GII81_RS08150	COG3879	Bacterial protein of unknown function (DUF881)
GII81_RS08155	COG3879	Bacterial protein of unknown function (DUF881)
GII81_RS08160	COG3856	small basic protein
GII81_RS08165	COG0849	cell division
GII81_RS08170	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GII81_RS08175	COG1404	Belongs to the peptidase S8 family
GII81_RS08175	COG4412	M6 family metalloprotease domain protein
GII81_RS08185	COG1191	sigma factor activity
GII81_RS08190	COG1191	sigma factor activity
GII81_RS08195	COG1119	ATPase activity
GII81_RS08200	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII81_RS08205	COG1873	PFAM PRC-barrel domain
GII81_RS08210	COG1496	oxidoreductase activity
GII81_RS08215	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GII81_RS08220	COG1799	cell septum assembly
GII81_RS08225	COG0762	integral membrane protein
GII81_RS08230	COG2302	S4 RNA-binding domain
GII81_RS08235	COG3599	regulation of cell shape
GII81_RS08240	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GII81_RS08245	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GII81_RS08250	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GII81_RS08255	COG0564	pseudouridine synthase activity
GII81_RS08260	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GII81_RS08265	COG2233	PERMEase
GII81_RS08270	COG0540	Belongs to the ATCase OTCase family
GII81_RS08275	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GII81_RS08280	COG0505	Belongs to the CarA family
GII81_RS08285	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GII81_RS08290	COG0543	2 iron, 2 sulfur cluster binding
GII81_RS08295	COG0167	dihydroorotate dehydrogenase activity
GII81_RS08300	COG0284	orotidine-5'-phosphate decarboxylase activity
GII81_RS08305	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GII81_RS08310	COG0175	sulfate reduction
GII81_RS08315	COG0306	phosphate transporter
GII81_RS08320	COG2046	Belongs to the sulfate adenylyltransferase family
GII81_RS08325	COG0529	Catalyzes the synthesis of activated sulfate
GII81_RS08330	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GII81_RS08335	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
GII81_RS08340	COG1648	precorrin-2 dehydrogenase activity
GII81_RS08345	COG1293	RNA-binding protein homologous to eukaryotic snRNP
GII81_RS08350	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GII81_RS08355	COG1561	YicC-like family, N-terminal region
GII81_RS08365	COG0194	GDP metabolic process
GII81_RS08370	COG1758	RNA polymerase activity
GII81_RS08375	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GII81_RS08380	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GII81_RS08385	COG0242	peptide deformylase activity
GII81_RS08390	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GII81_RS08395	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GII81_RS08395	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GII81_RS08400	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GII81_RS08405	COG0631	protein serine/threonine phosphatase activity
GII81_RS08410	COG2815	serine threonine protein kinase
GII81_RS08410	COG0515	serine threonine protein kinase
GII81_RS08415	COG1162	GTPase activity
GII81_RS08420	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GII81_RS08425	COG1564	THIamine pyrophosphokinase
GII81_RS08435	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GII81_RS08440	COG1302	Protein conserved in bacteria
GII81_RS08445	COG1461	Dihydroxyacetone kinase
GII81_RS08450	COG1760	l-serine dehydratase
GII81_RS08455	COG1760	l-serine dehydratase
GII81_RS08460	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GII81_RS08465	COG1349	DNA-binding transcription factor activity
GII81_RS08465	COG2050	protein possibly involved in aromatic compounds catabolism
GII81_RS08470	COG0416	fatty acid biosynthetic process
GII81_RS08475	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GII81_RS08480	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_RS08490	COG0571	ribonuclease III activity
GII81_RS08495	COG1196	nuclear chromosome segregation
GII81_RS08500	COG0552	protein localization to endoplasmic reticulum
GII81_RS08510	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GII81_RS08515	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GII81_RS08520	COG0228	four-way junction DNA binding
GII81_RS08525	COG1837	Belongs to the UPF0109 family
GII81_RS08535	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GII81_RS08540	COG0336	Belongs to the RNA methyltransferase TrmD family
GII81_RS08545	COG0335	large ribosomal subunit rRNA binding
GII81_RS08550	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GII81_RS08555	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GII81_RS08565	COG2257	FlhB HrpN YscU SpaS Family
GII81_RS08570	COG0045	succinate-CoA ligase (ADP-forming) activity
GII81_RS08575	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GII81_RS08580	COG0758	DNA mediated transformation
GII81_RS08585	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GII81_RS08590	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GII81_RS08595	COG4974	Belongs to the 'phage' integrase family
GII81_RS08600	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GII81_RS08605	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GII81_RS08610	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GII81_RS08615	COG1815	bacterial-type flagellum-dependent cell motility
GII81_RS08620	COG1558	bacterial-type flagellum-dependent cell motility
GII81_RS08625	COG1677	Flagellar hook-basal body complex protein FliE
GII81_RS08630	COG1766	The M ring may be actively involved in energy transduction
GII81_RS08635	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GII81_RS08640	COG1317	bacterial-type flagellum organization
GII81_RS08645	COG1157	protein secretion by the type III secretion system
GII81_RS08650	COG2882	bacterial-type flagellum organization
GII81_RS08655	COG3334	PFAM MgtE intracellular
GII81_RS08660	COG3144	bacterial-type flagellum assembly
GII81_RS08665	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GII81_RS08670	COG4786	Flagellar basal body rod
GII81_RS08675	COG1582	Flagellar protein (FlbD)
GII81_RS08680	COG1580	Controls the rotational direction of flagella during chemotaxis
GII81_RS08685	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GII81_RS08690	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GII81_RS08690	COG1776	CheC inhibitor of MCP methylation
GII81_RS08695	COG2201	protein-glutamate methylesterase activity
GII81_RS08700	COG3190	flagellar
GII81_RS08705	COG1338	Plays a role in the flagellum-specific transport system
GII81_RS08710	COG1987	bacterial-type flagellum assembly
GII81_RS08715	COG1684	flagellar biosynthetic protein fliR
GII81_RS08720	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GII81_RS08725	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GII81_RS08730	COG1419	protein localization to endoplasmic reticulum
GII81_RS08735	COG0455	bacterial-type flagellum organization
GII81_RS08740	COG2201	protein-glutamate methylesterase activity
GII81_RS08745	COG2198	Histidine kinase
GII81_RS08745	COG0643	Histidine kinase
GII81_RS08750	COG0835	chemotaxis
GII81_RS08755	COG1776	CheC inhibitor of MCP methylation
GII81_RS08760	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GII81_RS08765	COG1191	sigma factor activity
GII81_RS08775	COG0052	Belongs to the universal ribosomal protein uS2 family
GII81_RS08780	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GII81_RS08785	COG0528	UMP kinase activity
GII81_RS08790	COG0233	cytoplasmic translational termination
GII81_RS08795	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GII81_RS08800	COG4589	Belongs to the CDS family
GII81_RS08805	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GII81_RS08810	COG0750	zinc metalloprotease
GII81_RS08815	COG0442	prolyl-tRNA aminoacylation
GII81_RS08820	COG2176	DNA-directed DNA polymerase activity
GII81_RS08825	COG0779	Required for maturation of 30S ribosomal subunits
GII81_RS08830	COG0195	Participates in both transcription termination and antitermination
GII81_RS08835	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GII81_RS08840	COG1358	cellular component organization or biogenesis
GII81_RS08845	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GII81_RS08850	COG1550	Protein conserved in bacteria
GII81_RS08855	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GII81_RS08860	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GII81_RS08865	COG0196	riboflavin kinase activity
GII81_RS08870	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GII81_RS08875	COG1185	polyribonucleotide nucleotidyltransferase activity
GII81_RS08880	COG0726	polysaccharide deacetylase
GII81_RS08885	COG0612	Peptidase, M16
GII81_RS08890	COG1873	PFAM PRC-barrel domain
GII81_RS08895	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GII81_RS08900	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GII81_RS08905	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GII81_RS08910	COG0527	aspartate kinase activity
GII81_RS08915	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GII81_RS08920	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GII81_RS08925	COG0740	serine-type endopeptidase activity
GII81_RS08935	COG4980	gas vesicle protein
GII81_RS08935	COG1674	ftsk spoiiie
GII81_RS08940	COG2188	Transcriptional regulator
GII81_RS08945	COG2814	Major facilitator Superfamily
GII81_RS08950	COG0612	Peptidase, M16
GII81_RS08955	COG0612	Peptidase, M16
GII81_RS08960	COG0300	oxidoreductase activity
GII81_RS08975	COG1426	Protein conserved in bacteria
GII81_RS08980	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GII81_RS08985	COG1058	Belongs to the CinA family
GII81_RS08985	COG1546	Belongs to the CinA family
GII81_RS08990	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GII81_RS08995	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GII81_RS09000	COG1418	mRNA catabolic process
GII81_RS09005	COG1692	metallophosphoesterase
GII81_RS09010	COG2359	stage V sporulation protein S
GII81_RS09015	COG1063	alcohol dehydrogenase
GII81_RS09020	COG0156	8-amino-7-oxononanoate synthase activity
GII81_RS09025	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GII81_RS09030	COG4550	Control of competence regulator ComK, YlbF/YmcA
GII81_RS09040	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GII81_RS09045	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GII81_RS09060	COG3226	Transcriptional regulator
GII81_RS09065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII81_RS09075	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GII81_RS09080	COG3321	synthase
GII81_RS09085	COG2070	2-Nitropropane dioxygenase
GII81_RS09085	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GII81_RS09090	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII81_RS09095	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GII81_RS09100	COG3425	synthase
GII81_RS09105	COG1024	Enoyl-CoA hydratase
GII81_RS09110	COG1024	Enoyl-CoA hydratase
GII81_RS09115	COG3321	synthase
GII81_RS09115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII81_RS09115	COG0318	PFAM AMP-dependent synthetase and ligase
GII81_RS09115	COG0300	oxidoreductase activity
GII81_RS09115	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_RS09120	COG4221	oxidoreductase activity
GII81_RS09120	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII81_RS09120	COG0300	oxidoreductase activity
GII81_RS09120	COG3321	synthase
GII81_RS09125	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_RS09125	COG3321	synthase
GII81_RS09125	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII81_RS09125	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII81_RS09125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII81_RS09130	COG4221	oxidoreductase activity
GII81_RS09130	COG3321	synthase
GII81_RS09130	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_RS09130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII81_RS09135	COG3321	synthase
GII81_RS09135	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GII81_RS09135	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GII81_RS09135	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII81_RS09140	COG2124	cytochrome p450
GII81_RS09150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII81_RS09155	COG1404	Belongs to the peptidase S8 family
GII81_RS09165	COG4195	phage-related replication protein
GII81_RS09170	COG1764	response to oxidative stress
GII81_RS09175	COG2076	Multidrug Resistance protein
GII81_RS09180	COG2076	Multidrug Resistance protein
GII81_RS09195	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GII81_RS09200	COG1923	regulation of RNA biosynthetic process
GII81_RS09215	COG1780	Probably involved in ribonucleotide reductase function
GII81_RS09220	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GII81_RS09225	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GII81_RS09230	COG4112	unkown
GII81_RS09235	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII81_RS09240	COG0464	growth
GII81_RS09245	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GII81_RS09250	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
GII81_RS09255	COG0789	Transcriptional regulator
GII81_RS09260	COG0174	glutamine synthetase
GII81_RS09300	COG1598	PFAM Uncharacterised protein family UPF0150
GII81_RS09380	COG0463	Glycosyl transferase, family 2
GII81_RS09395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII81_RS09410	COG3655	Transcriptional regulator
GII81_RS09425	COG0135	phosphoribosylanthranilate isomerase activity
GII81_RS09435	COG2211	Major facilitator Superfamily
GII81_RS09440	COG3507	Belongs to the glycosyl hydrolase 43 family
GII81_RS09445	COG1940	carbohydrate kinase activity
GII81_RS09450	COG2115	Belongs to the xylose isomerase family
GII81_RS09455	COG1070	Carbohydrate kinase
GII81_RS09465	COG1525	nuclease
GII81_RS09470	COG2814	Major facilitator Superfamily
GII81_RS09475	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GII81_RS09485	COG0756	dUTP diphosphatase activity
GII81_RS09520	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GII81_RS09530	COG3832	glyoxalase III activity
GII81_RS09575	COG4195	phage-related replication protein
GII81_RS09585	COG0346	lactoylglutathione lyase activity
GII81_RS09590	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GII81_RS09595	COG1388	LysM domain
GII81_RS09600	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GII81_RS09605	COG4224	UPF0291 protein
GII81_RS09610	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GII81_RS09620	COG3763	UPF0154 protein
GII81_RS09630	COG0785	Cytochrome C biogenesis protein
GII81_RS09635	COG2201	protein-glutamate methylesterase activity
GII81_RS09640	COG4846	Membrane protein involved in cytochrome C biogenesis
GII81_RS09650	COG0071	Belongs to the small heat shock protein (HSP20) family
GII81_RS09665	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GII81_RS09670	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII81_RS09690	COG0824	Thioesterase
GII81_RS09700	COG4841	protein insertion into membrane
GII81_RS09705	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GII81_RS09710	COG1832	CoA-binding protein
GII81_RS09715	COG0187	DNA topoisomerase II activity
GII81_RS09720	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GII81_RS09730	COG1115	amino acid carrier protein
GII81_RS09745	COG5520	Belongs to the glycosyl hydrolase 30 family
GII81_RS09750	COG3507	Belongs to the glycosyl hydrolase 43 family
GII81_RS09755	COG2246	polysaccharide biosynthetic process
GII81_RS09760	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GII81_RS09765	COG0586	Pfam SNARE associated Golgi protein
GII81_RS09770	COG2404	hydrolase activity, acting on ester bonds
GII81_RS09775	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GII81_RS09780	COG1024	Enoyl-CoA hydratase
GII81_RS09785	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GII81_RS09790	COG0511	ligase activity, forming carbon-carbon bonds
GII81_RS09795	COG0439	Biotin carboxylase
GII81_RS09800	COG0318	PFAM AMP-dependent synthetase and ligase
GII81_RS09805	COG1960	acyl-CoA dehydrogenase activity
GII81_RS09820	COG1649	PFAM Uncharacterised BCR, COG1649
GII81_RS09830	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GII81_RS09830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII81_RS09835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII81_RS09840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII81_RS09845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII81_RS09850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII81_RS09855	COG2027	D-alanyl-D-alanine carboxypeptidase
GII81_RS09860	COG2017	converts alpha-aldose to the beta-anomer
GII81_RS09865	COG0534	Mate efflux family protein
GII81_RS09880	COG0582	viral genome integration into host DNA
GII81_RS09885	COG0166	Belongs to the GPI family
GII81_RS09890	COG0405	Gamma-glutamyltransferase
GII81_RS09895	COG0583	DNA-binding transcription factor activity
GII81_RS09900	COG0604	alcohol dehydrogenase
GII81_RS09905	COG0493	'glutamate synthase
GII81_RS09910	COG0067	glutamate synthase
GII81_RS09910	COG0069	glutamate synthase activity
GII81_RS09910	COG0070	glutamate synthase
GII81_RS09915	COG0583	DNA-binding transcription factor activity
GII81_RS09920	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GII81_RS09925	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII81_RS09935	COG0300	oxidoreductase activity
GII81_RS09940	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GII81_RS09950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII81_RS09965	COG2814	Major facilitator Superfamily
GII81_RS09970	COG1070	Carbohydrate kinase
GII81_RS09975	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GII81_RS09980	COG0243	molybdopterin cofactor binding
GII81_RS10010	COG0840	transmembrane signaling receptor activity
GII81_RS10010	COG5278	phosphoserine phosphatase activity
GII81_RS10015	COG2368	4-hydroxyphenylacetate
GII81_RS10020	COG4305	rare lipoprotein A
GII81_RS10025	COG3619	membrane
GII81_RS10030	COG3866	Pectate lyase
GII81_RS10035	COG2135	peptidase activity
GII81_RS10045	COG2140	Oxalate decarboxylase
GII81_RS10055	COG0456	acetyltransferase
GII81_RS10075	COG2720	vancomycin resistance protein
GII81_RS10085	COG3655	Transcriptional regulator
GII81_RS10090	COG3739	integral membrane protein
GII81_RS10095	COG0583	DNA-binding transcription factor activity
GII81_RS10100	COG0697	spore germination
GII81_RS10110	COG0693	protein deglycase activity
GII81_RS10115	COG2367	Beta-lactamase
GII81_RS10140	COG3848	Pyruvate phosphate dikinase
GII81_RS10140	COG0574	Belongs to the PEP-utilizing enzyme family
GII81_RS10145	COG0726	polysaccharide deacetylase
GII81_RS10150	COG2314	TM2 domain
GII81_RS10155	COG1396	sequence-specific DNA binding
GII81_RS10275	COG0457	Tetratricopeptide repeat
GII81_RS10310	COG4282	regulation of fungal-type cell wall biogenesis
GII81_RS10315	COG1231	oxidoreductase activity
GII81_RS10320	COG0582	viral genome integration into host DNA
GII81_RS10375	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII81_RS10420	COG5280	Phage tail tape measure protein TP901
GII81_RS10420	COG3953	SLT domain
GII81_RS10480	COG1403	HNH endonuclease
GII81_RS10550	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII81_RS10555	COG0662	Cupin 2, conserved barrel domain protein
GII81_RS10555	COG2207	Transcriptional regulator
GII81_RS10560	COG0456	acetyltransferase
GII81_RS10565	COG1309	transcriptional regulator
GII81_RS10570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII81_RS10575	COG3708	Transcriptional regulator
GII81_RS10580	COG2378	regulation of single-species biofilm formation
GII81_RS10590	COG0640	Transcriptional regulator
GII81_RS10595	COG0741	lytic transglycosylase activity
GII81_RS10600	COG2322	membrane
GII81_RS10615	COG1619	proteins homologs of microcin C7 resistance protein MccF
GII81_RS10620	COG3239	Fatty acid desaturase
GII81_RS10625	COG4585	Histidine kinase
GII81_RS10630	COG2197	response regulator
GII81_RS10635	COG3584	3D domain protein
GII81_RS10635	COG1388	LysM domain
GII81_RS10640	COG0514	ATP-dependent DNA helicase (RecQ)
GII81_RS10650	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GII81_RS10655	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GII81_RS10670	COG0071	Belongs to the small heat shock protein (HSP20) family
GII81_RS10695	COG1012	belongs to the aldehyde dehydrogenase family
GII81_RS10700	COG1657	PFAM Prenyltransferase squalene oxidase
GII81_RS10705	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GII81_RS10710	COG0733	neurotransmitter:sodium symporter activity
GII81_RS10715	COG0385	Bile acid
GII81_RS10720	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII81_RS10725	COG0567	Dehydrogenase, E1 component
GII81_RS10730	COG4548	von Willebrand factor, type A
GII81_RS10735	COG0714	Associated with various cellular activities
GII81_RS10740	COG2032	superoxide dismutase activity
GII81_RS10745	COG1388	LysM domain
GII81_RS10745	COG0791	NLP P60 protein
GII81_RS10750	COG1819	glycosyl
GII81_RS10755	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GII81_RS10760	COG0534	Mate efflux family protein
GII81_RS10765	COG1366	Belongs to the anti-sigma-factor antagonist family
GII81_RS10770	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GII81_RS10775	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GII81_RS10785	COG2962	Rard protein
GII81_RS10800	COG2610	gluconate transmembrane transporter activity
GII81_RS10805	COG1942	4-Oxalocrotonate Tautomerase
GII81_RS10810	COG1733	regulation of RNA biosynthetic process
GII81_RS10815	COG0778	Nitroreductase
GII81_RS10820	COG0400	carboxylic ester hydrolase activity
GII81_RS10825	COG0346	lactoylglutathione lyase activity
GII81_RS10835	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII81_RS10840	COG0793	Belongs to the peptidase S41A family
GII81_RS10840	COG3409	Peptidoglycan-binding domain 1 protein
GII81_RS10845	COG2226	methyltransferase
GII81_RS10855	COG1876	peptidase activity
GII81_RS10860	COG0813	purine-nucleoside phosphorylase activity
GII81_RS10875	COG0671	phosphoesterase, PA-phosphatase related
GII81_RS10895	COG4479	Belongs to the UPF0346 family
GII81_RS10905	COG1509	lysine 2,3-aminomutase activity
GII81_RS10910	COG0456	acetyltransferase
GII81_RS10915	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII81_RS10920	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GII81_RS10925	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GII81_RS10930	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GII81_RS10945	COG0456	acetyltransferase
GII81_RS10950	COG0463	Glycosyl transferase, family 2
GII81_RS10965	COG4641	Protein conserved in bacteria
GII81_RS10970	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
GII81_RS10975	COG1086	Polysaccharide biosynthesis protein
GII81_RS10980	COG3331	DNA recombination
GII81_RS11075	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII81_RS11080	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GII81_RS11100	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GII81_RS11100	COG1372	Participates in initiation and elongation during chromosome replication
GII81_RS11105	COG1780	Probably involved in ribonucleotide reductase function
GII81_RS11195	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GII81_RS11210	COG3584	3D domain protein
GII81_RS11215	COG0587	DNA-directed DNA polymerase activity
GII81_RS11220	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GII81_RS11225	COG0358	DNA primase activity
GII81_RS11230	COG0305	Participates in initiation and elongation during chromosome replication
GII81_RS11240	COG2887	Belongs to the helicase family. UvrD subfamily
GII81_RS11270	COG3420	alginic acid biosynthetic process
GII81_RS11270	COG5434	Belongs to the glycosyl hydrolase 28 family
GII81_RS11275	COG4195	phage-related replication protein
GII81_RS11295	COG2135	peptidase activity
GII81_RS11300	COG1793	dna ligase
GII81_RS11390	COG3645	SOS response
GII81_RS11390	COG3646	Phage regulatory protein
GII81_RS11425	COG3655	Transcriptional regulator
GII81_RS11510	COG3655	Transcriptional regulator
GII81_RS11585	COG0776	regulation of translation
GII81_RS11615	COG4373	Mu-like prophage FluMu protein gp28
GII81_RS11715	COG0582	viral genome integration into host DNA
GII81_RS11720	COG1396	sequence-specific DNA binding
GII81_RS11730	COG0741	lytic transglycosylase activity
GII81_RS11730	COG0739	heme binding
GII81_RS11730	COG1196	nuclear chromosome segregation
GII81_RS11740	COG2433	Pfam Transposase IS66
GII81_RS11755	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII81_RS11770	COG0457	Tetratricopeptide repeat
GII81_RS11775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII81_RS11785	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GII81_RS11790	COG2226	methyltransferase
GII81_RS11795	COG2211	Major facilitator Superfamily
GII81_RS11800	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GII81_RS11840	COG5444	nuclease activity
GII81_RS11845	COG4282	regulation of fungal-type cell wall biogenesis
GII81_RS11855	COG1525	nuclease
GII81_RS11875	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GII81_RS11880	COG1086	Polysaccharide biosynthesis protein
GII81_RS11885	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GII81_RS11890	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GII81_RS11895	COG1846	Transcriptional regulator
GII81_RS11900	COG0534	Mate efflux family protein
GII81_RS11910	COG4698	Protein conserved in bacteria
GII81_RS11915	COG2755	lipolytic protein G-D-S-L family
GII81_RS11920	COG1999	signal sequence binding
GII81_RS11930	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GII81_RS11935	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GII81_RS11940	COG1272	protein, Hemolysin III
GII81_RS11945	COG0204	Acyl-transferase
GII81_RS11950	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GII81_RS11955	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GII81_RS11960	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GII81_RS11970	COG2521	methyltransferase
GII81_RS11970	COG2136	Putative SAM-dependent methyltransferase
GII81_RS11980	COG0129	dihydroxy-acid dehydratase activity
GII81_RS11985	COG1413	lyase activity
GII81_RS11990	COG1418	mRNA catabolic process
GII81_RS11995	COG0386	Belongs to the glutathione peroxidase family
GII81_RS12000	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GII81_RS12005	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GII81_RS12015	COG1278	Cold shock
GII81_RS12035	COG0328	RNA-DNA hybrid ribonuclease activity
GII81_RS12040	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GII81_RS12045	COG0328	RNA-DNA hybrid ribonuclease activity
GII81_RS12055	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GII81_RS12070	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GII81_RS12080	COG1755	Isoprenylcysteine carboxyl methyltransferase
GII81_RS12085	COG3424	synthase
GII81_RS12090	COG2233	PERMEase
GII81_RS12095	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GII81_RS12100	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GII81_RS12110	COG0800	Aldolase
GII81_RS12115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII81_RS12120	COG1609	Transcriptional regulator
GII81_RS12125	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
GII81_RS12130	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_RS12135	COG1199	ATP-dependent helicase activity
GII81_RS12150	COG0116	Belongs to the methyltransferase superfamily
GII81_RS12165	COG4474	Belongs to the UPF0398 family
GII81_RS12180	COG3359	exonuclease
GII81_RS12185	COG1205	dead DEAH box helicase
GII81_RS12185	COG1111	helicase
GII81_RS12190	COG2190	(PTS) system
GII81_RS12195	COG0071	Belongs to the small heat shock protein (HSP20) family
GII81_RS12230	COG3331	DNA recombination
GII81_RS12235	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII81_RS12235	COG4499	WXG100 protein secretion system (Wss), protein YukC
GII81_RS12245	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GII81_RS12250	COG3935	DnaD domain protein
GII81_RS12255	COG0017	Asparaginyl-tRNA synthetase
GII81_RS12260	COG0436	Aminotransferase
GII81_RS12265	COG5353	protein conserved in bacteria
GII81_RS12275	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GII81_RS12275	COG1199	ATP-dependent helicase activity
GII81_RS12280	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GII81_RS12285	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GII81_RS12290	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GII81_RS12295	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GII81_RS12295	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GII81_RS12300	COG0617	tRNA 3'-terminal CCA addition
GII81_RS12305	COG0438	transferase activity, transferring glycosyl groups
GII81_RS12310	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GII81_RS12315	COG1803	Methylglyoxal synthase
GII81_RS12320	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GII81_RS12325	COG1694	Mazg nucleotide pyrophosphohydrolase
GII81_RS12330	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII81_RS12340	COG4347	Protein of unknown function (DUF1405)
GII81_RS12345	COG2010	Cytochrome c
GII81_RS12345	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GII81_RS12350	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GII81_RS12355	COG0723	plastoquinol--plastocyanin reductase activity
GII81_RS12365	COG5582	Belongs to the UPF0302 family
GII81_RS12370	COG0457	Tetratricopeptide repeat
GII81_RS12375	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GII81_RS12380	COG0287	Prephenate dehydrogenase
GII81_RS12390	COG0159	tryptophan synthase activity
GII81_RS12395	COG0133	tryptophan synthase activity
GII81_RS12400	COG0135	phosphoribosylanthranilate isomerase activity
GII81_RS12410	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GII81_RS12415	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GII81_RS12420	COG4401	Chorismate mutase type I
GII81_RS12425	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GII81_RS12430	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GII81_RS12435	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GII81_RS12440	COG0105	UTP biosynthetic process
GII81_RS12445	COG0142	geranyltranstransferase activity
GII81_RS12450	COG2226	methyltransferase
GII81_RS12455	COG0142	geranyltranstransferase activity
GII81_RS12465	COG0302	gtp cyclohydrolase
GII81_RS12470	COG0776	regulation of translation
GII81_RS12475	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GII81_RS12490	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GII81_RS12495	COG1160	GTP binding
GII81_RS12520	COG1304	FMN binding
GII81_RS12525	COG0539	negative regulation of cytoplasmic translation
GII81_RS12530	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GII81_RS12540	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
GII81_RS12545	COG2959	enzyme of heme biosynthesis
GII81_RS12550	COG3409	Peptidoglycan-binding domain 1 protein
GII81_RS12550	COG3773	Cell wall hydrolase
GII81_RS12555	COG2339	peptidase activity
GII81_RS12560	COG0492	ferredoxin-NADP+ reductase activity
GII81_RS12565	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GII81_RS12570	COG4862	establishment of competence for transformation
GII81_RS12575	COG1408	metallophosphoesterase
GII81_RS12585	COG1388	LysM domain
GII81_RS12590	COG1266	CAAX protease self-immunity
GII81_RS12595	COG0514	ATP-dependent DNA helicase (RecQ)
GII81_RS12600	COG4955	Helix-turn-helix domain
GII81_RS12605	COG1141	Ferredoxin
GII81_RS12610	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GII81_RS12615	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GII81_RS12620	COG0710	3-dehydroquinate dehydratase activity
GII81_RS12630	COG1595	DNA-templated transcription, initiation
GII81_RS12635	COG5002	protein histidine kinase activity
GII81_RS12640	COG0745	RESPONSE REGULATOR receiver
GII81_RS12645	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GII81_RS12650	COG1333	cytochrome c biogenesis protein
GII81_RS12655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII81_RS12660	COG1187	pseudouridine synthase activity
GII81_RS12665	COG0700	Nucleoside recognition
GII81_RS12670	COG2715	membrane protein required for spore maturation
GII81_RS12675	COG1686	Belongs to the peptidase S11 family
GII81_RS12685	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GII81_RS12690	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GII81_RS12695	COG1547	Domain of unknown function (DUF309)
GII81_RS12700	COG0456	acetyltransferase
GII81_RS12705	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GII81_RS12710	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GII81_RS12710	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GII81_RS12715	COG0307	riboflavin synthase, alpha
GII81_RS12720	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GII81_RS12720	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GII81_RS12730	COG0681	Belongs to the peptidase S26 family
GII81_RS12740	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
GII81_RS12765	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GII81_RS12770	COG4086	secreted protein
GII81_RS12775	COG0019	diaminopimelate decarboxylase activity
GII81_RS12780	COG0697	spore germination
GII81_RS12795	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GII81_RS12815	COG1191	sigma factor activity
GII81_RS12820	COG2172	sigma factor antagonist activity
GII81_RS12825	COG1366	Belongs to the anti-sigma-factor antagonist family
GII81_RS12830	COG1686	Belongs to the peptidase S11 family
GII81_RS12835	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GII81_RS12840	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GII81_RS12845	COG4974	Belongs to the 'phage' integrase family
GII81_RS12855	COG0735	belongs to the Fur family
GII81_RS12860	COG1300	Membrane
GII81_RS12870	COG0281	malic enzyme
GII81_RS12875	COG1757	Na H antiporter
GII81_RS12880	COG1027	Aspartate ammonia-lyase
GII81_RS12885	COG0252	asparaginase activity
GII81_RS12890	COG1396	sequence-specific DNA binding
GII81_RS12895	COG1379	DNA repair
GII81_RS12900	COG0494	nUDIX hydrolase
GII81_RS12910	COG0667	Aldo Keto reductase
GII81_RS12920	COG1073	alpha beta
GII81_RS12930	COG4918	Iron-sulphur cluster biosynthesis
GII81_RS12935	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GII81_RS12935	COG0456	acetyltransferase
GII81_RS12940	COG2329	Antibiotic biosynthesis monooxygenase
GII81_RS12945	COG0456	acetyltransferase
GII81_RS12955	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GII81_RS12965	COG2211	Major facilitator Superfamily
GII81_RS12970	COG0346	lactoylglutathione lyase activity
GII81_RS12975	COG1072	(Pantothenic acid kinase))
GII81_RS12980	COG3048	D-serine ammonia-lyase activity
GII81_RS12985	COG0300	oxidoreductase activity
GII81_RS12990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII81_RS12995	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII81_RS13000	COG4187	Peptidase family M20/M25/M40
GII81_RS13005	COG1902	pentaerythritol trinitrate reductase activity
GII81_RS13010	COG0596	Alpha beta hydrolase
GII81_RS13020	COG1234	tRNA 3'-trailer cleavage
GII81_RS13025	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GII81_RS13030	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GII81_RS13035	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GII81_RS13045	COG0706	membrane insertase activity
GII81_RS13050	COG3361	conserved protein (COG2071)
GII81_RS13055	COG2195	Cleaves the N-terminal amino acid of tripeptides
GII81_RS13060	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GII81_RS13065	COG0346	lactoylglutathione lyase activity
GII81_RS13075	COG1376	ErfK ybiS ycfS ynhG family protein
GII81_RS13080	COG4129	membrane
GII81_RS13085	COG1126	abc transporter atp-binding protein
GII81_RS13090	COG0765	amino acid transport
GII81_RS13095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII81_RS13105	COG1597	lipid kinase activity
GII81_RS13110	COG2814	Major facilitator Superfamily
GII81_RS13115	COG0789	Transcriptional regulator
GII81_RS13115	COG4978	Transcriptional regulator
GII81_RS13120	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII81_RS13125	COG0022	dehydrogenase e1 component
GII81_RS13130	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GII81_RS13135	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GII81_RS13140	COG3426	butyrate kinase activity
GII81_RS13145	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GII81_RS13150	COG0280	phosphate acetyltransferase
GII81_RS13155	COG3829	transcription factor binding
GII81_RS13155	COG3290	protein histidine kinase activity
GII81_RS13165	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GII81_RS13170	COG2079	MmgE PrpD family protein
GII81_RS13175	COG0372	Belongs to the citrate synthase family
GII81_RS13180	COG1960	acyl-CoA dehydrogenase activity
GII81_RS13185	COG1250	3-hydroxyacyl-CoA dehydrogenase
GII81_RS13190	COG0183	Belongs to the thiolase family
GII81_RS13195	COG0584	glycerophosphoryl diester phosphodiesterase
GII81_RS13200	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII81_RS13215	COG1902	pentaerythritol trinitrate reductase activity
GII81_RS13220	COG0745	RESPONSE REGULATOR receiver
GII81_RS13225	COG0750	zinc metalloprotease
GII81_RS13230	COG0497	DNA recombination
GII81_RS13235	COG1438	arginine binding
GII81_RS13240	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GII81_RS13245	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GII81_RS13250	COG0142	geranyltranstransferase activity
GII81_RS13255	COG1722	exodeoxyribonuclease VII activity
GII81_RS13260	COG1570	exodeoxyribonuclease VII activity
GII81_RS13265	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GII81_RS13270	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GII81_RS13275	COG1302	Protein conserved in bacteria
GII81_RS13280	COG0439	Biotin carboxylase
GII81_RS13285	COG0511	ligase activity, forming carbon-carbon bonds
GII81_RS13325	COG3854	ATPases associated with a variety of cellular activities
GII81_RS13335	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GII81_RS13340	COG0006	proline dipeptidase activity
GII81_RS13345	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GII81_RS13355	COG3872	metal-dependent enzyme
GII81_RS13365	COG1752	Esterase of the alpha-beta hydrolase superfamily
GII81_RS13370	COG1321	iron dependent repressor
GII81_RS13375	COG0095	Lipoate-protein ligase
GII81_RS13380	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII81_RS13385	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GII81_RS13390	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GII81_RS13395	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GII81_RS13400	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GII81_RS13415	COG1396	sequence-specific DNA binding
GII81_RS13425	COG0681	Belongs to the peptidase S26 family
GII81_RS13450	COG4940	Competence protein ComGF
GII81_RS13460	COG4970	Tfp pilus assembly protein FimT
GII81_RS13465	COG4537	Required for transformation and DNA binding
GII81_RS13470	COG1459	type II secretion system
GII81_RS13475	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GII81_RS13480	COG0517	IMP dehydrogenase activity
GII81_RS13485	COG0598	Magnesium transport protein CorA
GII81_RS13490	COG1253	flavin adenine dinucleotide binding
GII81_RS13495	COG1366	Belongs to the anti-sigma-factor antagonist family
GII81_RS13505	COG1393	Belongs to the ArsC family
GII81_RS13515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII81_RS13525	COG0011	TIGRFAM Protein of
GII81_RS13535	COG2866	Carboxypeptidase
GII81_RS13540	COG1368	sulfuric ester hydrolase activity
GII81_RS13545	COG1940	carbohydrate kinase activity
GII81_RS13550	COG4483	Protein conserved in bacteria
GII81_RS13555	COG0705	Rhomboid family
GII81_RS13555	COG0457	Tetratricopeptide repeat
GII81_RS13565	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GII81_RS13575	COG0438	transferase activity, transferring glycosyl groups
GII81_RS13590	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GII81_RS13595	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GII81_RS13600	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GII81_RS13605	COG0581	inorganic phosphate transmembrane transporter activity
GII81_RS13610	COG0573	inorganic phosphate transmembrane transporter activity
GII81_RS13615	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GII81_RS13620	COG0768	penicillin binding
GII81_RS13625	COG0477	Major facilitator Superfamily
GII81_RS13630	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GII81_RS13635	COG2839	Protein conserved in bacteria
GII81_RS13640	COG5521	maltodextrose utilization protein MalA
GII81_RS13645	COG1388	LysM domain
GII81_RS13650	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GII81_RS13655	COG4709	membrane
GII81_RS13660	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
GII81_RS13665	COG0735	belongs to the Fur family
GII81_RS13670	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII81_RS13680	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GII81_RS13685	COG0513	Belongs to the DEAD box helicase family
GII81_RS13695	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GII81_RS13700	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GII81_RS13705	COG2384	SAM-dependent methyltransferase
GII81_RS13710	COG2010	Cytochrome c
GII81_RS13715	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GII81_RS13720	COG0358	DNA primase activity
GII81_RS13725	COG1671	Belongs to the UPF0178 family
GII81_RS13730	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GII81_RS13735	COG0517	IMP dehydrogenase activity
GII81_RS13740	COG0751	glycine-tRNA ligase activity
GII81_RS13745	COG0752	glycyl-tRNA synthetase alpha subunit
GII81_RS13750	COG1381	Involved in DNA repair and RecF pathway recombination
GII81_RS13760	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GII81_RS13765	COG0295	cytidine deaminase activity
GII81_RS13770	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GII81_RS13775	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GII81_RS13780	COG1480	7TM receptor with intracellular HD hydrolase
GII81_RS13785	COG1702	phosphate starvation-inducible protein PhoH
GII81_RS13790	COG0561	phosphatase activity
GII81_RS13805	COG4864	UPF0365 protein
GII81_RS13810	COG1030	water channel activity
GII81_RS13815	COG1610	YqeY-like protein
GII81_RS13825	COG1283	sodium-dependent phosphate transmembrane transporter activity
GII81_RS13830	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GII81_RS13835	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GII81_RS13840	COG2264	protein methyltransferase activity
GII81_RS13845	COG0484	heat shock protein binding
GII81_RS13850	COG0443	Heat shock 70 kDa protein
GII81_RS13855	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GII81_RS13860	COG1420	regulation of RNA biosynthetic process
GII81_RS13865	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GII81_RS13870	COG0481	GTPase activity
GII81_RS13880	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII81_RS13885	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GII81_RS13890	COG0268	Binds directly to 16S ribosomal RNA
GII81_RS13895	COG1466	dna polymerase III delta subunit
GII81_RS13910	COG2333	competence protein COMEC
GII81_RS13910	COG0658	competence protein
GII81_RS13915	COG2131	deaminase
GII81_RS13920	COG1596	polysaccharide export
GII81_RS13920	COG1555	photosystem II stabilization
GII81_RS13925	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII81_RS13930	COG2226	methyltransferase
GII81_RS13935	COG0799	negative regulation of ribosome biogenesis
GII81_RS13940	COG1713	HD superfamily hydrolase involved in NAD metabolism
GII81_RS13945	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GII81_RS13950	COG1534	Rna-binding protein
GII81_RS13955	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GII81_RS13960	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GII81_RS13965	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GII81_RS13975	COG2755	lipolytic protein G-D-S-L family
GII81_RS13980	COG3409	Peptidoglycan-binding domain 1 protein
GII81_RS13980	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII81_RS13985	COG0398	Pfam SNARE associated Golgi protein
GII81_RS14000	COG3209	COG3209 Rhs family protein
GII81_RS14010	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GII81_RS14015	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GII81_RS14020	COG0798	PFAM Bile acid sodium symporter
GII81_RS14025	COG0346	lactoylglutathione lyase activity
GII81_RS14030	COG0640	Transcriptional regulator
GII81_RS14035	COG3403	YqcI/YcgG family
GII81_RS14055	COG0604	alcohol dehydrogenase
GII81_RS14080	COG0457	Tetratricopeptide repeat
GII81_RS14095	COG5444	nuclease activity
GII81_RS14120	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII81_RS14120	COG3409	Peptidoglycan-binding domain 1 protein
GII81_RS14125	COG4824	toxin secretion phage lysis holin
GII81_RS14155	COG3778	Protein conserved in bacteria
GII81_RS14160	COG3299	homolog of phage Mu protein gp47
GII81_RS14165	COG3628	GPW Gp25 family protein
GII81_RS14175	COG4193	domain, Protein
GII81_RS14180	COG1652	LysM domain
GII81_RS14185	COG3953	SLT domain
GII81_RS14185	COG5280	Phage tail tape measure protein TP901
GII81_RS14245	COG4653	Phage capsid family
GII81_RS14250	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GII81_RS14260	COG2369	cell adhesion
GII81_RS14265	COG5518	Phage portal protein
GII81_RS14270	COG1783	phage Terminase large subunit
GII81_RS14275	COG5484	DNA packaging
GII81_RS14285	COG1335	isochorismatase
GII81_RS14320	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
GII81_RS14330	COG1484	DNA-dependent DNA replication
GII81_RS14335	COG3935	DnaD domain protein
GII81_RS14340	COG3723	Recombinational DNA repair protein, rece pathway
GII81_RS14345	COG5377	YqaJ viral recombinase family
GII81_RS14380	COG3620	sequence-specific DNA binding
GII81_RS14390	COG0563	adenylate kinase activity
GII81_RS14395	COG2856	Zn peptidase
GII81_RS14410	COG5002	protein histidine kinase activity
GII81_RS14410	COG0642	Histidine kinase
GII81_RS14415	COG0745	RESPONSE REGULATOR receiver
GII81_RS14420	COG2311	Membrane
GII81_RS14430	COG0454	-acetyltransferase
GII81_RS14435	COG2249	NAD(P)H dehydrogenase (quinone) activity
GII81_RS14445	COG0730	response to heat
GII81_RS14450	COG0425	Belongs to the sulfur carrier protein TusA family
GII81_RS14455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII81_RS14455	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII81_RS14465	COG0425	Belongs to the sulfur carrier protein TusA family
GII81_RS14465	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII81_RS14475	COG1937	Protein conserved in bacteria
GII81_RS14480	COG0662	Cupin 2, conserved barrel domain protein
GII81_RS14490	COG4978	Transcriptional regulator
GII81_RS14490	COG0789	Transcriptional regulator
GII81_RS14495	COG2814	Major facilitator Superfamily
GII81_RS14500	COG0456	acetyltransferase
GII81_RS14505	COG1253	flavin adenine dinucleotide binding
GII81_RS14515	COG0697	spore germination
GII81_RS14520	COG0583	DNA-binding transcription factor activity
GII81_RS14525	COG2072	flavoprotein involved in K transport
GII81_RS14530	COG1230	cation diffusion facilitator family transporter
GII81_RS14535	COG1942	4-Oxalocrotonate Tautomerase
GII81_RS14540	COG0583	DNA-binding transcription factor activity
GII81_RS14550	COG1114	Component of the transport system for branched-chain amino acids
GII81_RS14555	COG1687	branched-chain amino acid
GII81_RS14560	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GII81_RS14565	COG1522	sequence-specific DNA binding
GII81_RS14575	COG2124	cytochrome p450
GII81_RS14580	COG1335	isochorismatase
GII81_RS14590	COG2318	DinB family
GII81_RS14600	COG2070	2-Nitropropane dioxygenase
GII81_RS14605	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GII81_RS14615	COG2186	Transcriptional regulator
GII81_RS14630	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_RS14635	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GII81_RS14640	COG3959	Transketolase, thiamine diphosphate binding domain
GII81_RS14650	COG0789	Transcriptional regulator
GII81_RS14650	COG4978	Transcriptional regulator
GII81_RS14655	COG2315	Protein conserved in bacteria
GII81_RS14665	COG3443	Belongs to the bacterial solute-binding protein 9 family
GII81_RS14670	COG1595	DNA-templated transcription, initiation
GII81_RS14675	COG0667	Aldo Keto reductase
GII81_RS14680	COG2851	Citrate transporter
GII81_RS14685	COG0583	DNA-binding transcription factor activity
GII81_RS14690	COG2828	Protein conserved in bacteria
GII81_RS14695	COG3409	Peptidoglycan-binding domain 1 protein
GII81_RS14700	COG5566	PFAM Mor transcription activator
GII81_RS14705	COG0596	Alpha beta hydrolase
GII81_RS14710	COG4991	sh3 domain protein
GII81_RS14715	COG4991	sh3 domain protein
GII81_RS14725	COG0346	lactoylglutathione lyase activity
GII81_RS14735	COG5577	PFAM Coat F domain
GII81_RS14740	COG1063	alcohol dehydrogenase
GII81_RS14750	COG5577	PFAM Coat F domain
GII81_RS14755	COG0789	Transcriptional regulator
GII81_RS14765	COG1064	alcohol dehydrogenase
GII81_RS14770	COG0693	protein deglycase activity
GII81_RS14775	COG1621	beta-fructofuranosidase activity
GII81_RS14780	COG3716	PTS system mannose fructose sorbose family IID component
GII81_RS14785	COG3715	PTS system
GII81_RS14790	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII81_RS14795	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII81_RS14800	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GII81_RS14800	COG3933	PFAM sigma-54 factor interaction domain-containing protein
GII81_RS14810	COG1113	amino acid transport
GII81_RS14815	COG1280	lysine exporter protein (LysE YggA)
GII81_RS14820	COG1378	Sugar-specific transcriptional regulator TrmB
GII81_RS14825	COG1595	DNA-templated transcription, initiation
GII81_RS14845	COG2124	cytochrome p450
GII81_RS14845	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GII81_RS14850	COG1309	transcriptional regulator
GII81_RS14855	COG2226	methyltransferase
GII81_RS14870	COG2116	formate transmembrane transporter activity
GII81_RS14875	COG5609	conserved protein (DUF2294)
GII81_RS14880	COG3383	formate dehydrogenase (NAD+) activity
GII81_RS14885	COG2427	Protein of unknown function (DUF1641)
GII81_RS14895	COG0626	cystathionine gamma-synthase activity
GII81_RS14900	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GII81_RS14905	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GII81_RS14910	COG2226	methyltransferase
GII81_RS14925	COG0768	penicillin binding
GII81_RS14930	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GII81_RS14935	COG0572	uridine kinase
GII81_RS14940	COG0826	peptidase U32
GII81_RS14945	COG0826	peptidase U32
GII81_RS14950	COG4122	O-methyltransferase activity
GII81_RS14955	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GII81_RS14960	COG3906	Belongs to the UPF0473 family
GII81_RS14965	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GII81_RS14970	COG4472	Bacterial protein of unknown function (DUF965)
GII81_RS14975	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GII81_RS14980	COG0628	permease
GII81_RS14985	COG1126	abc transporter atp-binding protein
GII81_RS14990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII81_RS14995	COG0765	amino acid transport
GII81_RS15000	COG0765	amino acid transport
GII81_RS15015	COG3881	PFAM PRC-barrel domain
GII81_RS15020	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GII81_RS15025	COG0457	Tetratricopeptide repeat
GII81_RS15030	COG0482	sulfurtransferase activity
GII81_RS15035	COG1104	cysteine desulfurase activity
GII81_RS15040	COG1959	2 iron, 2 sulfur cluster binding
GII81_RS15045	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GII81_RS15050	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GII81_RS15060	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GII81_RS15065	COG0124	histidyl-tRNA synthetase
GII81_RS15075	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII81_RS15075	COG4991	sh3 domain protein
GII81_RS15075	COG3103	Sh3 type 3 domain protein
GII81_RS15080	COG1490	D-aminoacyl-tRNA deacylase activity
GII81_RS15085	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GII81_RS15090	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GII81_RS15095	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GII81_RS15095	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GII81_RS15100	COG5416	Lipopolysaccharide assembly protein A domain
GII81_RS15105	COG0490	domain, Protein
GII81_RS15110	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GII81_RS15110	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GII81_RS15120	COG2244	polysaccharide biosynthetic process
GII81_RS15125	COG2323	membrane
GII81_RS15135	COG1862	Preprotein translocase
GII81_RS15140	COG0343	queuine tRNA-ribosyltransferase activity
GII81_RS15145	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GII81_RS15155	COG2255	four-way junction helicase activity
GII81_RS15160	COG0632	four-way junction helicase activity
GII81_RS15170	COG2814	Major facilitator Superfamily
GII81_RS15175	COG0673	inositol 2-dehydrogenase activity
GII81_RS15180	COG2112	serine threonine protein kinase
GII81_RS15200	COG1115	amino acid carrier protein
GII81_RS15205	COG0217	transcriptional regulatory protein
GII81_RS15215	COG1388	LysM domain
GII81_RS15220	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GII81_RS15225	COG0157	Belongs to the NadC ModD family
GII81_RS15230	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GII81_RS15235	COG1104	cysteine desulfurase activity
GII81_RS15240	COG1827	regulation of RNA biosynthetic process
GII81_RS15245	COG0077	Prephenate dehydratase
GII81_RS15250	COG4492	Belongs to the UPF0735 family
GII81_RS15255	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GII81_RS15260	COG3290	protein histidine kinase activity
GII81_RS15270	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GII81_RS15275	COG2868	ribosomal protein
GII81_RS15280	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GII81_RS15285	COG1994	Peptidase M50
GII81_RS15290	COG0739	heme binding
GII81_RS15295	COG2894	cell division
GII81_RS15300	COG0850	regulation of cytokinetic process
GII81_RS15305	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GII81_RS15315	COG1077	Cell shape determining protein MreB Mrl
GII81_RS15320	COG2003	Belongs to the UPF0758 family
GII81_RS15325	COG0424	maF-like protein
GII81_RS15335	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GII81_RS15340	COG0285	dihydrofolate synthase activity
GII81_RS15345	COG0525	valine-tRNA ligase activity
GII81_RS15355	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII81_RS15360	COG1388	LysM domain
GII81_RS15365	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GII81_RS15370	COG0113	porphobilinogen synthase activity
GII81_RS15375	COG1587	Uroporphyrinogen-III synthase
GII81_RS15380	COG0181	hydroxymethylbilane synthase activity
GII81_RS15385	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GII81_RS15390	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GII81_RS15400	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GII81_RS15405	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GII81_RS15410	COG0470	DNA polymerase III
GII81_RS15410	COG1067	ATP-dependent peptidase activity
GII81_RS15415	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GII81_RS15420	COG0544	peptidyl-prolyl cis-trans isomerase activity
GII81_RS15425	COG1477	protein flavinylation
GII81_RS15425	COG0457	Tetratricopeptide repeat
GII81_RS15430	COG0066	3-isopropylmalate dehydratase activity
GII81_RS15435	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GII81_RS15440	COG0473	3-isopropylmalate dehydrogenase activity
GII81_RS15445	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GII81_RS15450	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GII81_RS15455	COG0440	acetolactate synthase activity
GII81_RS15460	COG0028	Belongs to the TPP enzyme family
GII81_RS15470	COG0454	-acetyltransferase
GII81_RS15475	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
GII81_RS15485	COG0622	Phosphoesterase
GII81_RS15490	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GII81_RS15495	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GII81_RS15500	COG5401	PFAM Sporulation and spore germination
GII81_RS15505	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GII81_RS15510	COG1846	Transcriptional regulator
GII81_RS15515	COG2197	response regulator
GII81_RS15520	COG0824	Thioesterase
GII81_RS15525	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GII81_RS15530	COG1053	succinate dehydrogenase
GII81_RS15535	COG2009	succinate dehydrogenase
GII81_RS15540	COG1719	4-vinyl reductase, 4VR
GII81_RS15545	COG0527	aspartate kinase activity
GII81_RS15550	COG0322	excinuclease ABC activity
GII81_RS15555	COG3118	belongs to the thioredoxin family
GII81_RS15560	COG3534	alpha-L-arabinofuranosidase
GII81_RS15565	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GII81_RS15570	COG2086	electron transfer activity
GII81_RS15575	COG1024	Enoyl-CoA hydratase
GII81_RS15580	COG1309	transcriptional regulator
GII81_RS15585	COG0318	PFAM AMP-dependent synthetase and ligase
GII81_RS15590	COG3766	membrane
GII81_RS15595	COG1193	negative regulation of DNA recombination
GII81_RS15600	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GII81_RS15600	COG1796	DNA polymerase
GII81_RS15605	COG1286	toxin biosynthetic process
GII81_RS15610	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GII81_RS15615	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GII81_RS15620	COG0072	phenylalanine-tRNA ligase activity
GII81_RS15620	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII81_RS15625	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GII81_RS15635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GII81_RS15645	COG3835	regulator
GII81_RS15650	COG0277	FAD linked oxidase domain protein
GII81_RS15655	COG0247	lactate metabolic process
GII81_RS15670	COG1966	Carbon starvation protein
GII81_RS15675	COG3534	alpha-L-arabinofuranosidase
GII81_RS15680	COG0395	ABC-type sugar transport system, permease component
GII81_RS15685	COG1175	transmembrane transport
GII81_RS15690	COG1653	transport
GII81_RS15695	COG0371	Dehydrogenase
GII81_RS15700	COG0647	UMP catabolic process
GII81_RS15705	COG0235	Class ii aldolase
GII81_RS15710	COG1069	ribulokinase activity
GII81_RS15715	COG2160	L-arabinose isomerase activity
GII81_RS15720	COG3507	Belongs to the glycosyl hydrolase 43 family
GII81_RS15725	COG1363	Peptidase, m42
GII81_RS15735	COG3326	Membrane
GII81_RS15740	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GII81_RS15745	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GII81_RS15750	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GII81_RS15760	COG1346	cytolysis
GII81_RS15765	COG1380	Effector of murein hydrolase LrgA
GII81_RS15770	COG3279	Response regulator of the LytR AlgR family
GII81_RS15775	COG3275	phosphorelay sensor kinase activity
GII81_RS15780	COG1011	Hydrolase
GII81_RS15785	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GII81_RS15795	COG0398	Pfam SNARE associated Golgi protein
GII81_RS15800	COG1484	DNA-dependent DNA replication
GII81_RS15805	COG3611	Membrane attachment protein
GII81_RS15810	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GII81_RS15815	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GII81_RS15820	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GII81_RS15825	COG1733	regulation of RNA biosynthetic process
GII81_RS15830	COG2814	Major facilitator Superfamily
GII81_RS15835	COG0656	L-ascorbic acid biosynthetic process
GII81_RS15840	COG0237	dephospho-CoA kinase activity
GII81_RS15845	COG1971	Probably functions as a manganese efflux pump
GII81_RS15850	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GII81_RS15855	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GII81_RS15855	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GII81_RS15860	COG5002	protein histidine kinase activity
GII81_RS15865	COG0745	RESPONSE REGULATOR receiver
GII81_RS15870	COG0039	L-malate dehydrogenase activity
GII81_RS15875	COG0538	isocitrate dehydrogenase activity
GII81_RS15880	COG0372	Belongs to the citrate synthase family
GII81_RS15885	COG2707	UPF0756 membrane protein
GII81_RS15890	COG0628	permease
GII81_RS15895	COG3030	protein affecting phage T7 exclusion by the F plasmid
GII81_RS15900	COG0469	pyruvate kinase activity
GII81_RS15905	COG0205	6-phosphofructokinase activity
GII81_RS15910	COG0825	malonyl-CoA metabolic process
GII81_RS15915	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GII81_RS15920	COG0281	malic enzyme
GII81_RS15925	COG0587	DNA-directed DNA polymerase activity
GII81_RS15945	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GII81_RS15955	COG4109	DRTGG domain
GII81_RS15960	COG0730	response to heat
GII81_RS15965	COG1473	amidohydrolase
GII81_RS15970	COG0196	riboflavin kinase activity
GII81_RS15975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII81_RS15980	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GII81_RS15985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII81_RS15990	COG1126	abc transporter atp-binding protein
GII81_RS15995	COG0765	amino acid transport
GII81_RS16000	COG0765	amino acid transport
GII81_RS16005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII81_RS16010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII81_RS16015	COG0454	-acetyltransferase
GII81_RS16020	COG0583	DNA-binding transcription factor activity
GII81_RS16025	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GII81_RS16030	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_RS16040	COG0165	Argininosuccinate lyase
GII81_RS16045	COG0137	argininosuccinate synthase activity
GII81_RS16050	COG0521	Mo-molybdopterin cofactor biosynthetic process
GII81_RS16055	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GII81_RS16065	COG0827	DNA restriction-modification system
GII81_RS16070	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GII81_RS16075	COG3874	Sporulation protein YtfJ
GII81_RS16085	COG1714	RDD family
GII81_RS16090	COG0616	signal peptide processing
GII81_RS16095	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GII81_RS16100	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GII81_RS16105	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GII81_RS16115	COG0301	tRNA thio-modification
GII81_RS16120	COG1104	cysteine desulfurase activity
GII81_RS16125	COG1114	Component of the transport system for branched-chain amino acids
GII81_RS16130	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GII81_RS16135	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GII81_RS16140	COG1309	transcriptional regulator
GII81_RS16145	COG1956	GAF domain-containing protein
GII81_RS16150	COG2203	Gaf domain
GII81_RS16150	COG2199	diguanylate cyclase activity
GII81_RS16160	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GII81_RS16165	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GII81_RS16170	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GII81_RS16175	COG0454	-acetyltransferase
GII81_RS16180	COG0517	IMP dehydrogenase activity
GII81_RS16185	COG0123	including yeast histone deacetylase and acetoin utilization protein
GII81_RS16190	COG1360	Flagellar Motor Protein
GII81_RS16195	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GII81_RS16200	COG1609	Transcriptional regulator
GII81_RS16205	COG1605	Chorismate mutase
GII81_RS16205	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GII81_RS16210	COG3118	belongs to the thioredoxin family
GII81_RS16215	COG4980	gas vesicle protein
GII81_RS16220	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GII81_RS16225	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GII81_RS16230	COG1674	ftsk spoiiie
GII81_RS16235	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII81_RS16240	COG4848	Belongs to the UPF0354 family
GII81_RS16245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII81_RS16260	COG1363	Peptidase, m42
GII81_RS16265	COG5584	Small secreted protein
GII81_RS16270	COG0281	malic enzyme
GII81_RS16275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII81_RS16280	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GII81_RS16290	COG0510	thiamine kinase activity
GII81_RS16295	COG1523	belongs to the glycosyl hydrolase 13 family
GII81_RS16300	COG1597	lipid kinase activity
GII81_RS16310	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GII81_RS16315	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GII81_RS16320	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII81_RS16325	COG2252	PERMEase
GII81_RS16330	COG4473	ABC transporter
GII81_RS16335	COG1131	(ABC) transporter
GII81_RS16340	COG1349	DNA-binding transcription factor activity
GII81_RS16345	COG1187	pseudouridine synthase activity
GII81_RS16350	COG2244	polysaccharide biosynthetic process
GII81_RS16355	COG2081	HI0933 family
GII81_RS16360	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GII81_RS16370	COG5578	integral membrane protein
GII81_RS16375	COG0673	inositol 2-dehydrogenase activity
GII81_RS16380	COG1653	transport
GII81_RS16385	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GII81_RS16390	COG4209	transmembrane transport
GII81_RS16395	COG2207	Transcriptional regulator
GII81_RS16400	COG1653	transport
GII81_RS16405	COG0395	ABC-type sugar transport system, permease component
GII81_RS16410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII81_RS16415	COG2124	cytochrome p450
GII81_RS16420	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GII81_RS16430	COG0156	8-amino-7-oxononanoate synthase activity
GII81_RS16435	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GII81_RS16445	COG1073	alpha beta
GII81_RS16450	COG1609	Transcriptional regulator
GII81_RS16455	COG1653	transport
GII81_RS16460	COG1175	transmembrane transport
GII81_RS16465	COG0395	ABC-type sugar transport system, permease component
GII81_RS16470	COG1486	melibiose metabolic process
GII81_RS16475	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII81_RS16480	COG0495	leucyl-tRNA aminoacylation
GII81_RS16490	COG1366	Belongs to the anti-sigma-factor antagonist family
GII81_RS16490	COG2202	Pas domain
GII81_RS16495	COG2814	Major facilitator Superfamily
GII81_RS16500	COG2433	Pfam Transposase IS66
GII81_RS16505	COG0577	efflux transmembrane transporter activity
GII81_RS16510	COG1136	(ABC) transporter
GII81_RS16515	COG2205	protein histidine kinase activity
GII81_RS16520	COG0745	RESPONSE REGULATOR receiver
GII81_RS16525	COG0577	efflux transmembrane transporter activity
GII81_RS16530	COG1136	(ABC) transporter
GII81_RS16545	COG1131	(ABC) transporter
GII81_RS16550	COG1725	Transcriptional regulator
GII81_RS16565	COG1242	4 iron, 4 sulfur cluster binding
GII81_RS16570	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GII81_RS16580	COG2267	carboxylic ester hydrolase activity
GII81_RS16585	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GII81_RS16590	COG1113	amino acid transport
GII81_RS16595	COG0367	asparagine synthase
GII81_RS16600	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GII81_RS16605	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GII81_RS16615	COG1506	peptidase
GII81_RS16620	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GII81_RS16625	COG1116	anion transmembrane transporter activity
GII81_RS16630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GII81_RS16635	COG0494	nUDIX hydrolase
GII81_RS16640	COG4824	toxin secretion phage lysis holin
GII81_RS16645	COG0783	Belongs to the Dps family
GII81_RS16660	COG1854	S-ribosylhomocysteine lyase activity
GII81_RS16665	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GII81_RS16670	COG0288	reversible hydration of carbon dioxide
GII81_RS16675	COG0254	rRNA binding
GII81_RS16680	COG1271	oxidase subunit
GII81_RS16685	COG1294	oxidase, subunit
GII81_RS16695	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GII81_RS16700	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GII81_RS16700	COG1321	iron dependent repressor
GII81_RS16705	COG1121	(ABC) transporter
GII81_RS16710	COG0803	Belongs to the bacterial solute-binding protein 9 family
GII81_RS16715	COG4948	Mandelate Racemase Muconate Lactonizing
GII81_RS16720	COG0318	PFAM AMP-dependent synthetase and ligase
GII81_RS16725	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GII81_RS16730	COG0596	Alpha beta hydrolase
GII81_RS16735	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GII81_RS16740	COG1169	isochorismate synthase
GII81_RS16745	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GII81_RS16750	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GII81_RS16755	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GII81_RS16760	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII81_RS16765	COG0438	transferase activity, transferring glycosyl groups
GII81_RS16775	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII81_RS16780	COG0438	transferase activity, transferring glycosyl groups
GII81_RS16785	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII81_RS16790	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
GII81_RS16795	COG0058	SHG alpha-glucan phosphorylase activity
GII81_RS16800	COG0297	glycogen (starch) synthase activity
GII81_RS16805	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GII81_RS16810	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GII81_RS16815	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GII81_RS16940	COG3859	Proton-coupled thiamine transporter YuaJ
GII81_RS16945	COG1247	-acetyltransferase
GII81_RS16950	COG2268	Band 7 protein
GII81_RS16955	COG1585	Membrane protein implicated in regulation of membrane protease activity
GII81_RS16960	COG2318	DinB family
GII81_RS16970	COG1454	alcohol dehydrogenase
GII81_RS16975	COG1012	belongs to the aldehyde dehydrogenase family
GII81_RS16980	COG1510	regulation of RNA biosynthetic process
GII81_RS16990	COG0569	domain protein
GII81_RS16995	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GII81_RS17000	COG4682	membrane
GII81_RS17005	COG1705	Flagellar rod assembly protein muramidase FlgJ
GII81_RS17010	COG0477	Major facilitator Superfamily
GII81_RS17015	COG5553	Cysteine dioxygenase type I
GII81_RS17025	COG1968	undecaprenyl-diphosphatase activity
GII81_RS17030	COG0628	permease
GII81_RS17035	COG0673	inositol 2-dehydrogenase activity
GII81_RS17040	COG4806	L-rhamnose isomerase
GII81_RS17045	COG3254	rhamnose metabolic process
GII81_RS17050	COG1070	Carbohydrate kinase
GII81_RS17055	COG1349	DNA-binding transcription factor activity
GII81_RS17060	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_RS17060	COG3347	Dehydrogenase
GII81_RS17065	COG0840	transmembrane signaling receptor activity
GII81_RS17070	COG0840	transmembrane signaling receptor activity
GII81_RS17075	COG0840	transmembrane signaling receptor activity
GII81_RS17080	COG0840	transmembrane signaling receptor activity
GII81_RS17100	COG0432	Pfam Uncharacterised protein family UPF0047
GII81_RS17110	COG0366	Alpha amylase catalytic
GII81_RS17115	COG1253	flavin adenine dinucleotide binding
GII81_RS17120	COG2738	Putative neutral zinc metallopeptidase
GII81_RS17135	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GII81_RS17150	COG0166	Belongs to the GPI family
GII81_RS17155	COG1979	alcohol dehydrogenase
GII81_RS17160	COG1979	alcohol dehydrogenase
GII81_RS17165	COG2155	Conserved Protein
GII81_RS17170	COG1098	S1 RNA binding domain
GII81_RS17175	COG0436	Aminotransferase
GII81_RS17180	COG1522	sequence-specific DNA binding
GII81_RS17185	COG2267	carboxylic ester hydrolase activity
GII81_RS17195	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GII81_RS17200	COG2205	protein histidine kinase activity
GII81_RS17210	COG5018	Exonuclease
GII81_RS17220	COG2814	Major facilitator Superfamily
GII81_RS17225	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII81_RS17230	COG3011	Protein conserved in bacteria
GII81_RS17240	COG3290	protein histidine kinase activity
GII81_RS17245	COG4565	transcriptional regulatory protein
GII81_RS17250	COG1744	ABC transporter substrate-binding protein PnrA-like
GII81_RS17255	COG3845	ABC transporter
GII81_RS17260	COG4603	Belongs to the binding-protein-dependent transport system permease family
GII81_RS17265	COG1079	Belongs to the binding-protein-dependent transport system permease family
GII81_RS17270	COG3493	citrate carrier protein
GII81_RS17280	COG2111	Na H antiporter
GII81_RS17280	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GII81_RS17285	COG2111	Na H antiporter
GII81_RS17290	COG1006	Multisubunit Na H antiporter MnhC subunit
GII81_RS17295	COG0651	ATP synthesis coupled electron transport
GII81_RS17300	COG1863	multisubunit Na H antiporter MnhE subunit
GII81_RS17305	COG2212	antiporter activity
GII81_RS17310	COG1320	monovalent cation:proton antiporter activity
GII81_RS17315	COG2050	protein possibly involved in aromatic compounds catabolism
GII81_RS17320	COG2197	response regulator
GII81_RS17325	COG4585	Histidine kinase
GII81_RS17335	COG0142	geranyltranstransferase activity
GII81_RS17355	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GII81_RS17360	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GII81_RS17365	COG1335	isochorismatase
GII81_RS17370	COG5506	Protein of unknown function (DUF1694)
GII81_RS17385	COG0628	permease
GII81_RS17400	COG1418	mRNA catabolic process
GII81_RS17405	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_RS17415	COG1511	domain protein
GII81_RS17420	COG1674	ftsk spoiiie
GII81_RS17420	COG0433	COG0433 Predicted ATPase
GII81_RS17425	COG4499	WXG100 protein secretion system (Wss), protein YukC
GII81_RS17430	COG5417	Belongs to the EsaB family
GII81_RS17435	COG4842	Belongs to the WXG100 family
GII81_RS17440	COG2508	Transcriptional regulator
GII81_RS17440	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GII81_RS17445	COG0686	Belongs to the AlaDH PNT family
GII81_RS17450	COG5634	Uncharacterized conserved protein (DUF2278)
GII81_RS17455	COG3251	PFAM MbtH domain protein
GII81_RS17460	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII81_RS17465	COG3433	isochorismatase activity
GII81_RS17465	COG1535	isochorismatase
GII81_RS17470	COG1021	2,3-dihydroxybenzoate-AMP ligase
GII81_RS17475	COG1169	isochorismate synthase
GII81_RS17480	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_RS17485	COG2819	hydrolase of the alpha beta superfamily
GII81_RS17490	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GII81_RS17495	COG1268	BioY protein
GII81_RS17500	COG2056	Na+-H+ antiporter family
GII81_RS17505	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GII81_RS17510	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
GII81_RS17515	COG3584	3D domain protein
GII81_RS17530	COG1252	NADH dehydrogenase
GII81_RS17535	COG0492	ferredoxin-NADP+ reductase activity
GII81_RS17545	COG0516	GMP reductase activity
GII81_RS17550	COG2808	Putative FMN-binding domain
GII81_RS17555	COG0456	acetyltransferase
GII81_RS17560	COG0316	Belongs to the HesB IscA family
GII81_RS17565	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GII81_RS17570	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GII81_RS17575	COG4844	belongs to the
GII81_RS17580	COG1252	NADH dehydrogenase
GII81_RS17585	COG4837	Protein of unknown function (DUF1462)
GII81_RS17590	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GII81_RS17595	COG0823	Involved in the tonB-independent uptake of proteins
GII81_RS17595	COG1506	peptidase
GII81_RS17595	COG4946	Tricorn protease homolog
GII81_RS17600	COG0083	homoserine kinase activity
GII81_RS17605	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GII81_RS17610	COG0460	homoserine dehydrogenase
GII81_RS17615	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII81_RS17620	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GII81_RS17625	COG0647	UMP catabolic process
GII81_RS17630	COG2445	Protein of unknown function DUF86
GII81_RS17635	COG4470	Protein conserved in bacteria
GII81_RS17645	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GII81_RS17650	COG0739	heme binding
GII81_RS17660	COG3377	Domain of unknown function (DUF1805)
GII81_RS17665	COG0737	Belongs to the 5'-nucleotidase family
GII81_RS17670	COG0730	response to heat
GII81_RS17675	COG1801	Protein of unknown function DUF72
GII81_RS17685	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GII81_RS17690	COG2508	Transcriptional regulator
GII81_RS17695	COG2233	PERMEase
GII81_RS17700	COG2233	PERMEase
GII81_RS17705	COG3648	Uricase
GII81_RS17705	COG3195	allantoin biosynthetic process
GII81_RS17710	COG2351	hydroxyisourate hydrolase activity
GII81_RS17720	COG2080	2 iron, 2 sulfur cluster binding
GII81_RS17725	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GII81_RS17730	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GII81_RS17735	COG2068	MobA-Related Protein
GII81_RS17740	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GII81_RS17745	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GII81_RS17750	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII81_RS17760	COG2356	endonuclease I
GII81_RS17765	COG3842	ATPase activity
GII81_RS17770	COG2188	Transcriptional regulator
GII81_RS17775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII81_RS17780	COG0395	ABC-type sugar transport system, permease component
GII81_RS17785	COG1175	transmembrane transport
GII81_RS17790	COG1653	transport
GII81_RS17795	COG2222	sugar isomerase
GII81_RS17800	COG0322	excinuclease ABC activity
GII81_RS17805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GII81_RS17820	COG0719	Fe-S assembly protein
GII81_RS17825	COG0822	iron-sulfur transferase activity
GII81_RS17830	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GII81_RS17835	COG0719	Fe-S assembly protein
GII81_RS17840	COG0396	ATPase activity
GII81_RS17850	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GII81_RS17855	COG1464	Belongs to the NlpA lipoprotein family
GII81_RS17860	COG2011	ABC-type metal ion transport system permease component
GII81_RS17865	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GII81_RS17875	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII81_RS17880	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GII81_RS17890	COG0509	glycine decarboxylation via glycine cleavage system
GII81_RS17895	COG1393	Belongs to the ArsC family
GII81_RS17900	COG1960	acyl-CoA dehydrogenase activity
GII81_RS17905	COG0183	Belongs to the thiolase family
GII81_RS17910	COG1024	Enoyl-CoA hydratase
GII81_RS17910	COG1250	3-hydroxyacyl-CoA dehydrogenase
GII81_RS17920	COG0506	proline dehydrogenase activity
GII81_RS17930	COG5577	PFAM Coat F domain
GII81_RS17935	COG1846	Transcriptional regulator
GII81_RS17940	COG0477	Major facilitator Superfamily
GII81_RS17945	COG1942	4-Oxalocrotonate Tautomerase
GII81_RS17950	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_RS17955	COG0583	DNA-binding transcription factor activity
GII81_RS17965	COG1120	ATPase activity
GII81_RS17980	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_RS17985	COG0783	Belongs to the Dps family
GII81_RS17990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII81_RS17995	COG0745	RESPONSE REGULATOR receiver
GII81_RS18000	COG2770	Histidine kinase
GII81_RS18000	COG2205	protein histidine kinase activity
GII81_RS18010	COG1309	transcriptional regulator
GII81_RS18015	COG0114	fumarate hydratase activity
GII81_RS18025	COG0697	spore germination
GII81_RS18030	COG0814	amino acid
GII81_RS18040	COG2197	response regulator
GII81_RS18045	COG4585	Histidine kinase
GII81_RS18050	COG4758	membrane
GII81_RS18055	COG3595	metallopeptidase activity
GII81_RS18060	COG1842	Phage shock protein A
GII81_RS18065	COG4758	membrane
GII81_RS18070	COG2814	Major facilitator Superfamily
GII81_RS18075	COG2096	Adenosyltransferase
GII81_RS18080	COG1120	ATPase activity
GII81_RS18085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII81_RS18090	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII81_RS18095	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_RS18100	COG3386	PFAM SMP-30 Gluconolaconase
GII81_RS18105	COG2205	protein histidine kinase activity
GII81_RS18110	COG0745	RESPONSE REGULATOR receiver
GII81_RS18120	COG1191	sigma factor activity
GII81_RS18130	COG2140	Oxalate decarboxylase
GII81_RS18140	COG0577	efflux transmembrane transporter activity
GII81_RS18145	COG1136	(ABC) transporter
GII81_RS18150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GII81_RS18155	COG1120	ATPase activity
GII81_RS18160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII81_RS18165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII81_RS18170	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII81_RS18175	COG0531	amino acid
GII81_RS18185	COG1988	membrane-bound metal-dependent
GII81_RS18190	COG1368	sulfuric ester hydrolase activity
GII81_RS18195	COG1910	domain protein
GII81_RS18200	COG0725	ABC transporter, periplasmic molybdate-binding protein
GII81_RS18205	COG4149	molybdate abc transporter
GII81_RS18210	COG0656	L-ascorbic acid biosynthetic process
GII81_RS18220	COG0025	NhaP-type Na H and K H
GII81_RS18225	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GII81_RS18230	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GII81_RS18235	COG3973	AAA domain
GII81_RS18245	COG2860	membrane
GII81_RS18250	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GII81_RS18255	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GII81_RS18260	COG2217	Heavy metal translocating P-type atpase
GII81_RS18265	COG2217	Heavy metal translocating P-type atpase
GII81_RS18270	COG2608	mercury ion transmembrane transporter activity
GII81_RS18275	COG1937	Protein conserved in bacteria
GII81_RS18280	COG0673	inositol 2-dehydrogenase activity
GII81_RS18285	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GII81_RS18290	COG1289	transmembrane transporter activity
GII81_RS18300	COG2076	Multidrug Resistance protein
GII81_RS18305	COG1309	transcriptional regulator
GII81_RS18310	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_RS18320	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GII81_RS18325	COG0557	exoribonuclease II activity
GII81_RS18330	COG1647	Serine aminopeptidase, S33
GII81_RS18335	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GII81_RS18340	COG0596	Alpha beta hydrolase
GII81_RS18345	COG1476	TRANSCRIPTIONal
GII81_RS18350	COG1396	sequence-specific DNA binding
GII81_RS18355	COG1396	sequence-specific DNA binding
GII81_RS18360	COG1733	regulation of RNA biosynthetic process
GII81_RS18365	COG0840	transmembrane signaling receptor activity
GII81_RS18370	COG1174	glycine betaine transport
GII81_RS18375	COG1732	Glycine betaine
GII81_RS18380	COG1174	glycine betaine transport
GII81_RS18385	COG1125	glycine betaine transport
GII81_RS18385	COG0517	IMP dehydrogenase activity
GII81_RS18390	COG1510	regulation of RNA biosynthetic process
GII81_RS18395	COG1174	glycine betaine transport
GII81_RS18400	COG1732	Glycine betaine
GII81_RS18405	COG1174	glycine betaine transport
GII81_RS18410	COG0517	IMP dehydrogenase activity
GII81_RS18410	COG1125	glycine betaine transport
GII81_RS18415	COG1510	regulation of RNA biosynthetic process
GII81_RS18420	COG2095	MarC family integral membrane protein
GII81_RS18430	COG3064	Membrane
GII81_RS18435	COG4640	response to antibiotic
GII81_RS18440	COG0456	acetyltransferase
GII81_RS18445	COG0148	phosphopyruvate hydratase activity
GII81_RS18450	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GII81_RS18455	COG0149	triose-phosphate isomerase activity
GII81_RS18460	COG0126	phosphoglycerate kinase activity
GII81_RS18465	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GII81_RS18470	COG2390	Transcriptional regulator
GII81_RS18475	COG2814	Major facilitator Superfamily
GII81_RS18480	COG1609	Transcriptional regulator
GII81_RS18485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII81_RS18495	COG0583	DNA-binding transcription factor activity
GII81_RS18500	COG0697	spore germination
GII81_RS18505	COG1113	amino acid transport
GII81_RS18510	COG3858	chitin binding
GII81_RS18515	COG1556	Lactate utilization protein
GII81_RS18520	COG1139	Iron-sulfur cluster binding protein
GII81_RS18525	COG0247	lactate metabolic process
GII81_RS18530	COG2197	response regulator
GII81_RS18535	COG4585	Histidine kinase
GII81_RS18540	COG0842	Transport permease protein
GII81_RS18545	COG1131	(ABC) transporter
GII81_RS18550	COG0596	Alpha beta hydrolase
GII81_RS18555	COG2208	phosphoserine phosphatase activity
GII81_RS18560	COG3867	Arabinogalactan endo-beta-1,4-galactanase
GII81_RS18565	COG1874	Beta-galactosidase
GII81_RS18570	COG3833	ABC-type maltose transport systems, permease component
GII81_RS18575	COG1175	transmembrane transport
GII81_RS18580	COG2182	Extracellular solute-binding protein
GII81_RS18585	COG1609	Transcriptional regulator
GII81_RS18590	COG2186	Transcriptional regulator
GII81_RS18595	COG1620	l-lactate permease
GII81_RS18600	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GII81_RS18610	COG5039	Polysaccharide pyruvyl transferase
GII81_RS18615	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GII81_RS18620	COG0110	maltose O-acetyltransferase activity
GII81_RS18625	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GII81_RS18630	COG2244	polysaccharide biosynthetic process
GII81_RS18635	COG1216	Glycosyl transferase, family 2
GII81_RS18640	COG5039	Polysaccharide pyruvyl transferase
GII81_RS18645	COG1216	Glycosyl transferase, family 2
GII81_RS18655	COG0438	transferase activity, transferring glycosyl groups
GII81_RS18660	COG1215	transferase activity, transferring glycosyl groups
GII81_RS18665	COG0438	transferase activity, transferring glycosyl groups
GII81_RS18670	COG1086	Polysaccharide biosynthesis protein
GII81_RS18675	COG0489	protein tyrosine kinase activity
GII81_RS18680	COG3944	biosynthesis protein
GII81_RS18685	COG1396	sequence-specific DNA binding
GII81_RS18690	COG2272	Belongs to the type-B carboxylesterase lipase family
GII81_RS18700	COG3479	Phenolic acid decarboxylase
GII81_RS18710	COG1794	racemase activity, acting on amino acids and derivatives
GII81_RS18715	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GII81_RS18720	COG1621	beta-fructofuranosidase activity
GII81_RS18725	COG1621	beta-fructofuranosidase activity
GII81_RS18730	COG0531	amino acid
GII81_RS18735	COG1309	transcriptional regulator
GII81_RS18740	COG2076	Multidrug Resistance protein
GII81_RS18745	COG2076	Multidrug Resistance protein
GII81_RS18755	COG0277	FAD linked oxidase domain protein
GII81_RS18760	COG3621	Patatin-like phospholipase
GII81_RS18770	COG0740	serine-type endopeptidase activity
GII81_RS18775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GII81_RS18780	COG0366	Alpha amylase catalytic
GII81_RS18785	COG1554	hydrolase, family 65, central catalytic
GII81_RS18790	COG5521	maltodextrose utilization protein MalA
GII81_RS18795	COG3833	ABC-type maltose transport systems, permease component
GII81_RS18800	COG1175	transmembrane transport
GII81_RS18805	COG2182	Extracellular solute-binding protein
GII81_RS18810	COG0366	Alpha amylase catalytic
GII81_RS18815	COG1609	Transcriptional regulator
GII81_RS18820	COG1611	Belongs to the LOG family
GII81_RS18825	COG1694	Mazg nucleotide pyrophosphohydrolase
GII81_RS18830	COG0659	secondary active sulfate transmembrane transporter activity
GII81_RS18835	COG0288	reversible hydration of carbon dioxide
GII81_RS18840	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GII81_RS18845	COG0577	efflux transmembrane transporter activity
GII81_RS18850	COG1136	(ABC) transporter
GII81_RS18855	COG5002	protein histidine kinase activity
GII81_RS18860	COG0745	RESPONSE REGULATOR receiver
GII81_RS18870	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GII81_RS18875	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII81_RS18880	COG1481	regulation of sporulation
GII81_RS18885	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GII81_RS18890	COG1660	Displays ATPase and GTPase activities
GII81_RS18895	COG1051	belongs to the nudix hydrolase family
GII81_RS18900	COG0492	ferredoxin-NADP+ reductase activity
GII81_RS18905	COG0791	NLP P60 protein
GII81_RS18905	COG3883	PFAM NLP P60 protein
GII81_RS18910	COG0457	Tetratricopeptide repeat
GII81_RS18915	COG1132	(ABC) transporter
GII81_RS18935	COG0140	phosphoribosyl-ATP diphosphatase activity
GII81_RS18935	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GII81_RS18940	COG0107	imidazoleglycerol-phosphate synthase activity
GII81_RS18945	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GII81_RS18950	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GII81_RS18955	COG0131	Imidazoleglycerol-phosphate dehydratase
GII81_RS18960	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GII81_RS18965	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GII81_RS18970	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GII81_RS18975	COG4990	cell redox homeostasis
GII81_RS18980	COG5297	Belongs to the glycosyl hydrolase family 6
GII81_RS18985	COG0110	maltose O-acetyltransferase activity
GII81_RS18990	COG0546	phosphoglycolate phosphatase activity
GII81_RS18995	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GII81_RS19000	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GII81_RS19005	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GII81_RS19010	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GII81_RS19015	COG0363	glucosamine-6-phosphate deaminase activity
GII81_RS19020	COG2188	Transcriptional regulator
GII81_RS19025	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GII81_RS19030	COG1846	Transcriptional regulator
GII81_RS19035	COG2124	cytochrome p450
GII81_RS19045	COG1846	Transcriptional regulator
GII81_RS19050	COG2814	Major facilitator Superfamily
GII81_RS19055	COG1950	PFAM Membrane protein of
GII81_RS19060	COG1983	PspC domain protein
GII81_RS19065	COG3595	metallopeptidase activity
GII81_RS19080	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GII81_RS19085	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GII81_RS19090	COG0556	nucleotide-excision repair
GII81_RS19095	COG4897	Protein conserved in bacteria
GII81_RS19100	COG0574	Belongs to the PEP-utilizing enzyme family
GII81_RS19100	COG3848	Pyruvate phosphate dikinase
GII81_RS19105	COG1309	transcriptional regulator
GII81_RS19110	COG2814	Major facilitator Superfamily
GII81_RS19115	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII81_RS19125	COG0793	Belongs to the peptidase S41A family
GII81_RS19125	COG3409	Peptidoglycan-binding domain 1 protein
GII81_RS19130	COG2177	Part of the ABC transporter FtsEX involved in
GII81_RS19135	COG2884	Cell division ATP-binding protein ftsE
GII81_RS19140	COG2010	Cytochrome c
GII81_RS19145	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII81_RS19155	COG0653	protein targeting
GII81_RS19160	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GII81_RS19175	COG1516	flagellar protein fliS
GII81_RS19180	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GII81_RS19185	COG1334	flagellar protein FlaG
GII81_RS19190	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GII81_RS19195	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GII81_RS19200	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
GII81_RS19210	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GII81_RS19215	COG1256	bacterial-type flagellum assembly
GII81_RS19215	COG4786	Flagellar basal body rod
GII81_RS19220	COG3418	PFAM FlgN family protein
GII81_RS19225	COG2747	anti-sigma28 factor FlgM
GII81_RS19235	COG1040	competence protein
GII81_RS19245	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GII81_RS19250	COG1307	EDD domain protein, DegV family
GII81_RS19255	COG2197	response regulator
GII81_RS19260	COG4585	Histidine kinase
GII81_RS19265	COG1739	Uncharacterized protein family UPF0029
GII81_RS19270	COG1316	TRANSCRIPTIONal
GII81_RS19275	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GII81_RS19280	COG0438	transferase activity, transferring glycosyl groups
GII81_RS19285	COG1215	transferase activity, transferring glycosyl groups
GII81_RS19290	COG3206	protein involved in exopolysaccharide biosynthesis
GII81_RS19295	COG3307	-O-antigen
GII81_RS19300	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GII81_RS19305	COG0438	transferase activity, transferring glycosyl groups
GII81_RS19305	COG0297	glycogen (starch) synthase activity
GII81_RS19310	COG2244	polysaccharide biosynthetic process
GII81_RS19325	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII81_RS19325	COG2247	cell wall binding repeat
GII81_RS19330	COG2247	cell wall binding repeat
GII81_RS19330	COG2385	sporulation resulting in formation of a cellular spore
GII81_RS19340	COG1316	TRANSCRIPTIONal
GII81_RS19345	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GII81_RS19365	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GII81_RS19370	COG1134	teichoic acid transport
GII81_RS19375	COG1682	transport, permease protein
GII81_RS19390	COG1215	transferase activity, transferring glycosyl groups
GII81_RS19390	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GII81_RS19395	COG0463	Glycosyl transferase, family 2
GII81_RS19440	COG4193	domain, Protein
GII81_RS19445	COG1482	cell wall glycoprotein biosynthetic process
GII81_RS19450	COG0697	spore germination
GII81_RS19455	COG0814	amino acid
GII81_RS19465	COG2814	Major facilitator Superfamily
GII81_RS19470	COG1316	TRANSCRIPTIONal
GII81_RS19475	COG0561	phosphatase activity
GII81_RS19480	COG0791	NLP P60 protein
GII81_RS19490	COG2843	Capsule synthesis protein
GII81_RS19500	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GII81_RS19505	COG1609	Transcriptional regulator
GII81_RS19510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII81_RS19515	COG1869	D-ribose catabolic process
GII81_RS19520	COG1129	ABC transporter
GII81_RS19525	COG1172	Belongs to the binding-protein-dependent transport system permease family
GII81_RS19530	COG1879	ABC-type sugar transport system periplasmic component
GII81_RS19535	COG3103	Sh3 type 3 domain protein
GII81_RS19545	COG2249	NAD(P)H dehydrogenase (quinone) activity
GII81_RS19550	COG3527	Alpha-acetolactate decarboxylase
GII81_RS19555	COG0028	Belongs to the TPP enzyme family
GII81_RS19560	COG0583	DNA-binding transcription factor activity
GII81_RS19565	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GII81_RS19580	COG5337	Spore coat protein CotH
GII81_RS19590	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GII81_RS19600	COG0405	Gamma-glutamyltransferase
GII81_RS19605	COG1522	sequence-specific DNA binding
GII81_RS19610	COG2059	Chromate
GII81_RS19615	COG2059	Chromate
GII81_RS19625	COG0655	NAD(P)H dehydrogenase (quinone) activity
GII81_RS19630	COG0583	DNA-binding transcription factor activity
GII81_RS19660	COG5444	nuclease activity
GII81_RS19680	COG3878	Protein conserved in bacteria
GII81_RS19685	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GII81_RS19690	COG4464	protein tyrosine phosphatase activity
GII81_RS19695	COG0489	protein tyrosine kinase activity
GII81_RS19700	COG3944	biosynthesis protein
GII81_RS19710	COG4715	Zinc finger, swim domain protein
GII81_RS19715	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GII81_RS19720	COG0561	phosphatase activity
GII81_RS19725	COG1349	DNA-binding transcription factor activity
GII81_RS19730	COG0629	single-stranded DNA binding
GII81_RS19745	COG3764	Sortase (surface protein transpeptidase)
GII81_RS19750	COG2972	Histidine kinase
GII81_RS19750	COG0745	RESPONSE REGULATOR receiver
GII81_RS19755	COG1970	mechanosensitive ion channel activity
GII81_RS19760	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GII81_RS19765	COG0457	Tetratricopeptide repeat
GII81_RS19770	COG4786	Flagellar basal body rod
GII81_RS19775	COG4786	Flagellar basal body rod
GII81_RS19780	COG1077	Cell shape determining protein MreB Mrl
GII81_RS19785	COG1609	Transcriptional regulator
GII81_RS19795	COG1846	Transcriptional regulator
GII81_RS19800	COG2814	Major facilitator Superfamily
GII81_RS19805	COG3420	alginic acid biosynthetic process
GII81_RS19810	COG1953	Uracil, thiamine, allantoin
GII81_RS19815	COG0477	Major facilitator Superfamily
GII81_RS19820	COG1335	isochorismatase
GII81_RS19830	COG0004	ammonium transporteR
GII81_RS19835	COG0347	Belongs to the P(II) protein family
GII81_RS19840	COG0671	phosphoesterase, PA-phosphatase related
GII81_RS19850	COG0739	heme binding
GII81_RS19855	COG1247	-acetyltransferase
GII81_RS19875	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GII81_RS19880	COG0789	Transcriptional regulator
GII81_RS19890	COG2910	NAD(P)H-binding
GII81_RS19895	COG1959	2 iron, 2 sulfur cluster binding
GII81_RS19900	COG0804	urea catabolic process
GII81_RS19905	COG0832	Belongs to the urease beta subunit family
GII81_RS19910	COG0831	urea catabolic process
GII81_RS19925	COG3237	CsbD-like
GII81_RS19930	COG1994	Peptidase M50
GII81_RS19935	COG0457	Tetratricopeptide repeat
GII81_RS19940	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GII81_RS19945	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GII81_RS19955	COG2304	oxidoreductase activity
GII81_RS19965	COG2304	oxidoreductase activity
GII81_RS19970	COG2385	sporulation resulting in formation of a cellular spore
GII81_RS19975	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GII81_RS19985	COG4836	Membrane
GII81_RS19995	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GII81_RS20000	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GII81_RS20005	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GII81_RS20010	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GII81_RS20015	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GII81_RS20020	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GII81_RS20030	COG0356	it plays a direct role in the translocation of protons across the membrane
GII81_RS20040	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GII81_RS20045	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GII81_RS20050	COG4475	Protein of unknown function (DUF436)
GII81_RS20055	COG0698	ribose 5-phosphate isomerase
GII81_RS20060	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GII81_RS20065	COG1971	Probably functions as a manganese efflux pump
GII81_RS20070	COG0009	L-threonylcarbamoyladenylate synthase
GII81_RS20075	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GII81_RS20095	COG2890	protein-(glutamine-N5) methyltransferase activity
GII81_RS20100	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GII81_RS20105	COG0346	lactoylglutathione lyase activity
GII81_RS20110	COG0789	Transcriptional regulator
GII81_RS20115	COG0679	Auxin Efflux Carrier
GII81_RS20120	COG0281	malic enzyme
GII81_RS20125	COG1435	thymidine kinase activity
GII81_RS20135	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GII81_RS20145	COG1494	fructose-1,6-bisphosphatase
GII81_RS20150	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GII81_RS20155	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GII81_RS20160	COG0191	fructose-bisphosphate aldolase activity
GII81_RS20165	COG2204	response regulator
GII81_RS20170	COG4821	SIS domain
GII81_RS20175	COG0504	CTP synthase activity
GII81_RS20180	COG3343	RNA polymerase activity
GII81_RS20185	COG1960	acyl-CoA dehydrogenase activity
GII81_RS20190	COG2181	nitrate reductase activity
GII81_RS20190	COG0247	lactate metabolic process
GII81_RS20195	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GII81_RS20200	COG4294	response to UV
GII81_RS20210	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GII81_RS20215	COG1132	(ABC) transporter
GII81_RS20220	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GII81_RS20225	COG2181	nitrate reductase activity
GII81_RS20230	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GII81_RS20235	COG1140	nitrate reductase beta subunit
GII81_RS20240	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GII81_RS20245	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GII81_RS20255	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GII81_RS20260	COG2223	nitrite transmembrane transporter activity
GII81_RS20265	COG0018	arginyl-trna synthetase
GII81_RS20270	COG4506	Protein conserved in bacteria
GII81_RS20285	COG0535	radical SAM domain protein
GII81_RS20295	COG1131	(ABC) transporter
GII81_RS20300	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GII81_RS20305	COG0612	Peptidase, M16
GII81_RS20310	COG0612	Peptidase, M16
GII81_RS20320	COG3391	amine dehydrogenase activity
GII81_RS20325	COG3391	amine dehydrogenase activity
GII81_RS20335	COG0457	Tetratricopeptide repeat
GII81_RS20365	COG1131	(ABC) transporter
GII81_RS20375	COG0010	Belongs to the arginase family
GII81_RS20380	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GII81_RS20385	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII81_RS20395	COG1994	Peptidase M50
GII81_RS20400	COG1942	4-Oxalocrotonate Tautomerase
GII81_RS20405	COG1846	Transcriptional regulator
GII81_RS20410	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GII81_RS20415	COG0477	Major facilitator Superfamily
GII81_RS20420	COG1959	2 iron, 2 sulfur cluster binding
GII81_RS20425	COG3465	dGTPase activity
GII81_RS20430	COG1078	dGTPase activity
GII81_RS20435	COG4844	belongs to the
GII81_RS20445	COG0697	spore germination
GII81_RS20450	COG0095	Lipoate-protein ligase
GII81_RS20455	COG0583	DNA-binding transcription factor activity
GII81_RS20460	COG0280	phosphate acetyltransferase
GII81_RS20465	COG3253	May function as heme-dependent peroxidase
GII81_RS20470	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_RS20475	COG0436	Aminotransferase
GII81_RS20480	COG2814	Major facilitator Superfamily
GII81_RS20485	COG0151	Belongs to the GarS family
GII81_RS20490	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_RS20495	COG1917	Cupin 2, conserved barrel domain protein
GII81_RS20500	COG0077	Prephenate dehydratase
GII81_RS20505	COG2814	Major facilitator Superfamily
GII81_RS20510	COG0833	amino acid
GII81_RS20515	COG4187	Peptidase family M20/M25/M40
GII81_RS20520	COG1012	belongs to the aldehyde dehydrogenase family
GII81_RS20525	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GII81_RS20535	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
GII81_RS20540	COG1091	dTDP-4-dehydrorhamnose reductase activity
GII81_RS20545	COG1088	dTDP-glucose 4,6-dehydratase activity
GII81_RS20550	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GII81_RS20555	COG3980	spore coat polysaccharide biosynthesis protein
GII81_RS20560	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
GII81_RS20565	COG2089	acid synthase
GII81_RS20570	COG0456	acetyltransferase
GII81_RS20575	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GII81_RS20580	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GII81_RS20585	COG0463	Glycosyl transferase, family 2
GII81_RS20595	COG2363	Small membrane protein
GII81_RS20600	COG2233	PERMEase
GII81_RS20615	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GII81_RS20620	COG1216	Glycosyl transferase, family 2
GII81_RS20625	COG0351	phosphomethylpyrimidine kinase
GII81_RS20635	COG1621	beta-fructofuranosidase activity
GII81_RS20640	COG1263	PTS System
GII81_RS20640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII81_RS20645	COG2116	formate transmembrane transporter activity
GII81_RS20650	COG3711	transcriptional antiterminator
GII81_RS20660	COG1404	Belongs to the peptidase S8 family
GII81_RS20665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII81_RS20670	COG0778	Nitroreductase
GII81_RS20675	COG0772	Belongs to the SEDS family
GII81_RS20685	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GII81_RS20690	COG1845	cytochrome c oxidase, subunit III
GII81_RS20695	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GII81_RS20700	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GII81_RS20705	COG2261	transglycosylase associated protein
GII81_RS20710	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GII81_RS20715	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GII81_RS20720	COG2246	polysaccharide biosynthetic process
GII81_RS20725	COG1309	transcriptional regulator
GII81_RS20735	COG3162	membrane
GII81_RS20740	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII81_RS20745	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GII81_RS20750	COG2837	iron assimilation
GII81_RS20755	COG2822	iron ion transport
GII81_RS20760	COG0672	)-iron permease
GII81_RS20765	COG0352	thiamine-phosphate diphosphorylase activity
GII81_RS20770	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GII81_RS20775	COG0583	DNA-binding transcription factor activity
GII81_RS20780	COG1380	Effector of murein hydrolase LrgA
GII81_RS20785	COG1346	cytolysis
GII81_RS20790	COG2814	Major facilitator Superfamily
GII81_RS20795	COG4895	conserved protein (DUF2196)
GII81_RS20800	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GII81_RS20805	COG0346	lactoylglutathione lyase activity
GII81_RS20810	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII81_RS20815	COG1404	Belongs to the peptidase S8 family
GII81_RS20820	COG1263	PTS System
GII81_RS20820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII81_RS20825	COG3711	transcriptional antiterminator
GII81_RS20830	COG1442	glycosyl transferase family 8
GII81_RS20835	COG5522	Integral membrane protein (intg_mem_TP0381)
GII81_RS20840	COG1846	Transcriptional regulator
GII81_RS20845	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GII81_RS20850	COG2234	aminopeptidase activity
GII81_RS20870	COG2357	RelA SpoT domain protein
GII81_RS20875	COG1575	Belongs to the MenA family. Type 1 subfamily
GII81_RS20890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII81_RS20895	COG1696	Membrane protein involved in D-alanine export
GII81_RS20900	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII81_RS20905	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GII81_RS20910	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
GII81_RS20915	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII81_RS20920	COG1486	melibiose metabolic process
GII81_RS20925	COG1447	Phosphotransferase system cellobiose-specific component IIA
GII81_RS20930	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII81_RS20935	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII81_RS20940	COG3711	transcriptional antiterminator
GII81_RS20940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII81_RS20950	COG2094	Belongs to the DNA glycosylase MPG family
GII81_RS20955	COG0753	catalase activity
GII81_RS20965	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GII81_RS20970	COG1131	(ABC) transporter
GII81_RS20990	COG1595	DNA-templated transcription, initiation
GII81_RS20995	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GII81_RS21000	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GII81_RS21005	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GII81_RS21010	COG4988	ABC transporter
GII81_RS21015	COG1294	oxidase, subunit
GII81_RS21020	COG1271	oxidase subunit
GII81_RS21025	COG3493	citrate carrier protein
GII81_RS21030	COG0501	Belongs to the peptidase M48B family
GII81_RS21040	COG0726	polysaccharide deacetylase
GII81_RS21045	COG3842	ATPase activity
GII81_RS21050	COG2508	Transcriptional regulator
GII81_RS21055	COG1012	belongs to the aldehyde dehydrogenase family
GII81_RS21060	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII81_RS21070	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GII81_RS21075	COG1881	PFAM PEBP family protein
GII81_RS21080	COG0583	DNA-binding transcription factor activity
GII81_RS21090	COG4585	Histidine kinase
GII81_RS21095	COG2197	response regulator
GII81_RS21100	COG2195	Cleaves the N-terminal amino acid of tripeptides
GII81_RS21110	COG4894	glucomannan catabolic process
GII81_RS21115	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GII81_RS21120	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GII81_RS21125	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_RS21130	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GII81_RS21135	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GII81_RS21140	COG2610	gluconate transmembrane transporter activity
GII81_RS21145	COG0500	methyltransferase
GII81_RS21150	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GII81_RS21165	COG0693	protein deglycase activity
GII81_RS21165	COG0753	catalase activity
GII81_RS21170	COG2851	Citrate transporter
GII81_RS21175	COG2273	Hydrolase Family 16
GII81_RS21180	COG3711	transcriptional antiterminator
GII81_RS21190	COG2270	Major facilitator Superfamily
GII81_RS21195	COG0513	Belongs to the DEAD box helicase family
GII81_RS21200	COG2755	lipolytic protein G-D-S-L family
GII81_RS21200	COG3401	FG-GAP repeat protein
GII81_RS21230	COG0697	spore germination
GII81_RS21235	COG0589	response to stress
GII81_RS21240	COG2723	6-phospho-beta-galactosidase activity
GII81_RS21245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII81_RS21245	COG2190	(PTS) system
GII81_RS21245	COG1263	PTS System
GII81_RS21260	COG5444	nuclease activity
GII81_RS21275	COG3507	Belongs to the glycosyl hydrolase 43 family
GII81_RS21290	COG2986	histidine ammonia-lyase
GII81_RS21295	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GII81_RS21300	COG1228	amidohydrolase
GII81_RS21305	COG0010	Belongs to the arginase family
GII81_RS21310	COG0833	amino acid
GII81_RS21315	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GII81_RS21320	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GII81_RS21325	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GII81_RS21330	COG2390	Transcriptional regulator
GII81_RS21340	COG3192	ethanolamine utilization protein
GII81_RS21345	COG2079	MmgE PrpD family protein
GII81_RS21350	COG1473	amidohydrolase
GII81_RS21355	COG1126	abc transporter atp-binding protein
GII81_RS21360	COG0765	amino acid transport
GII81_RS21365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII81_RS21370	COG0456	acetyltransferase
GII81_RS21375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII81_RS21385	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
GII81_RS21390	COG0561	phosphatase activity
GII81_RS21420	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII81_RS21425	COG5294	Protein conserved in bacteria
GII81_RS21430	COG0577	efflux transmembrane transporter activity
GII81_RS21435	COG1136	(ABC) transporter
GII81_RS21440	COG2205	protein histidine kinase activity
GII81_RS21445	COG0745	RESPONSE REGULATOR receiver
GII81_RS21450	COG0191	fructose-bisphosphate aldolase activity
GII81_RS21455	COG1082	Xylose isomerase domain protein TIM barrel
GII81_RS21460	COG1082	Xylose isomerase domain protein TIM barrel
GII81_RS21465	COG0673	inositol 2-dehydrogenase activity
GII81_RS21470	COG2814	Major facilitator Superfamily
GII81_RS21475	COG1082	Xylose isomerase domain protein TIM barrel
GII81_RS21480	COG3962	Belongs to the TPP enzyme family
GII81_RS21485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII81_RS21495	COG1012	belongs to the aldehyde dehydrogenase family
GII81_RS21500	COG1349	DNA-binding transcription factor activity
GII81_RS21505	COG0667	Aldo Keto reductase
GII81_RS21520	COG2814	Major facilitator Superfamily
GII81_RS21525	COG0326	Molecular chaperone. Has ATPase activity
GII81_RS21535	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_RS21540	COG1309	transcriptional regulator
GII81_RS21545	COG1012	belongs to the aldehyde dehydrogenase family
GII81_RS21550	COG1714	RDD family
GII81_RS21555	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GII81_RS21565	COG1714	RDD family
GII81_RS21570	COG2311	Membrane
GII81_RS21575	COG1917	Cupin 2, conserved barrel domain protein
GII81_RS21580	COG1309	transcriptional regulator
GII81_RS21585	COG1028	Short-chain dehydrogenase reductase Sdr
GII81_RS21590	COG1846	Transcriptional regulator
GII81_RS21595	COG1380	Effector of murein hydrolase LrgA
GII81_RS21600	COG1346	cytolysis
GII81_RS21605	COG5039	Polysaccharide pyruvyl transferase
GII81_RS21610	COG1929	Belongs to the glycerate kinase type-1 family
GII81_RS21615	COG1802	Transcriptional regulator
GII81_RS21620	COG1070	Carbohydrate kinase
GII81_RS21625	COG2610	gluconate transmembrane transporter activity
GII81_RS21630	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GII81_RS21635	COG0450	alkyl hydroperoxide reductase
GII81_RS21640	COG3634	alkyl hydroperoxide reductase activity
GII81_RS21650	COG2723	6-phospho-beta-galactosidase activity
GII81_RS21655	COG2190	(PTS) system
GII81_RS21660	COG2190	(PTS) system
GII81_RS21660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII81_RS21660	COG1263	PTS System
GII81_RS21665	COG2188	Transcriptional regulator
GII81_RS21675	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
GII81_RS21710	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GII81_RS21725	COG1063	alcohol dehydrogenase
GII81_RS21745	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GII81_RS21750	COG0456	acetyltransferase
GII81_RS21755	COG0457	Tetratricopeptide repeat
GII81_RS21765	COG0010	Belongs to the arginase family
GII81_RS21770	COG0833	amino acid
GII81_RS21775	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GII81_RS21780	COG3829	transcription factor binding
GII81_RS21785	COG5002	protein histidine kinase activity
GII81_RS21790	COG0745	RESPONSE REGULATOR receiver
GII81_RS21810	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII81_RS21815	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GII81_RS21820	COG4853	Protein conserved in bacteria
GII81_RS21825	COG4863	YycH protein
GII81_RS21830	COG5002	protein histidine kinase activity
GII81_RS21835	COG0745	RESPONSE REGULATOR receiver
GII81_RS21865	COG0346	lactoylglutathione lyase activity
GII81_RS21870	COG0305	Participates in initiation and elongation during chromosome replication
GII81_RS21885	COG3093	addiction module antidote protein HigA
GII81_RS21890	COG2807	transmembrane transport
GII81_RS21895	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GII81_RS21900	COG0359	binds to the 23S rRNA
GII81_RS21905	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
GII81_RS21910	COG4241	membrane
GII81_RS21920	COG5577	PFAM Coat F domain
GII81_RS21925	COG1733	regulation of RNA biosynthetic process
GII81_RS21930	COG1227	inorganic diphosphatase activity
GII81_RS21945	COG2271	Major facilitator Superfamily
GII81_RS21950	COG0789	Transcriptional regulator
GII81_RS21950	COG4978	Transcriptional regulator
GII81_RS21960	COG4319	ketosteroid isomerase
GII81_RS21965	COG1357	PFAM Pentapeptide repeats (8 copies)
GII81_RS21970	COG2814	Major facilitator Superfamily
GII81_RS21975	COG0583	DNA-binding transcription factor activity
GII81_RS21980	COG2153	protein acetylation
GII81_RS21990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII81_RS21995	COG1846	Transcriptional regulator
GII81_RS22000	COG2153	protein acetylation
GII81_RS22005	COG2364	Membrane
GII81_RS22010	COG0456	acetyltransferase
GII81_RS22015	COG2315	Protein conserved in bacteria
GII81_RS22020	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GII81_RS22030	COG2814	Major facilitator Superfamily
GII81_RS22040	COG1331	Highly conserved protein containing a thioredoxin domain
GII81_RS22055	COG0789	Transcriptional regulator
GII81_RS22060	COG0697	spore germination
GII81_RS22070	COG1280	lysine exporter protein (LysE YggA)
GII81_RS22075	COG1331	Highly conserved protein containing a thioredoxin domain
GII81_RS22085	COG1266	CAAX protease self-immunity
GII81_RS22090	COG0477	Major facilitator Superfamily
GII81_RS22090	COG2814	Major facilitator Superfamily
GII81_RS22095	COG0110	maltose O-acetyltransferase activity
GII81_RS22100	COG0346	lactoylglutathione lyase activity
GII81_RS22105	COG1609	Transcriptional regulator
GII81_RS22110	COG0708	Exodeoxyribonuclease III
GII81_RS22115	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GII81_RS22120	COG0629	single-stranded DNA binding
GII81_RS22125	COG0360	Binds together with S18 to 16S ribosomal RNA
GII81_RS22130	COG0012	GTP binding
GII81_RS22135	COG0243	molybdopterin cofactor binding
GII81_RS22140	COG4481	Protein conserved in bacteria
GII81_RS22145	COG3949	Membrane
GII81_RS22155	COG1475	DNA binding
GII81_RS22160	COG1192	Involved in chromosome partitioning
GII81_RS22170	COG1475	DNA binding
GII81_RS22175	COG0357	Ribosomal RNA small subunit methyltransferase G
GII81_RS22180	COG0445	tRNA wobble uridine modification
GII81_RS22185	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GII81_RS22190	COG1847	R3H domain protein
GII81_RS22195	COG0706	membrane insertase activity
GII81_RS22200	COG0594	ribonuclease P activity