locus-tag	class	description
D0808_RS00010	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D0808_RS00020	COG0405	Gamma-glutamyltransferase
D0808_RS00025	COG1522	sequence-specific DNA binding
D0808_RS00030	COG2059	Chromate
D0808_RS00035	COG2059	Chromate
D0808_RS00045	COG0655	NAD(P)H dehydrogenase (quinone) activity
D0808_RS00050	COG0583	DNA-binding transcription factor activity
D0808_RS00055	COG1515	deoxyribonuclease V activity
D0808_RS00080	COG5444	nuclease activity
D0808_RS00095	COG3878	Protein conserved in bacteria
D0808_RS00100	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D0808_RS00105	COG4464	protein tyrosine phosphatase activity
D0808_RS00110	COG0489	protein tyrosine kinase activity
D0808_RS00115	COG3944	biosynthesis protein
D0808_RS00125	COG4715	Zinc finger, swim domain protein
D0808_RS00130	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D0808_RS00135	COG0561	phosphatase activity
D0808_RS00140	COG1349	DNA-binding transcription factor activity
D0808_RS00145	COG0629	single-stranded DNA binding
D0808_RS00160	COG3764	Sortase (surface protein transpeptidase)
D0808_RS00170	COG3279	Response regulator of the LytR AlgR family
D0808_RS00175	COG0745	RESPONSE REGULATOR receiver
D0808_RS00175	COG2972	Histidine kinase
D0808_RS00180	COG1970	mechanosensitive ion channel activity
D0808_RS00185	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D0808_RS00190	COG0457	Tetratricopeptide repeat
D0808_RS00195	COG4786	Flagellar basal body rod
D0808_RS00200	COG4786	Flagellar basal body rod
D0808_RS00205	COG1077	Cell shape determining protein MreB Mrl
D0808_RS00210	COG1609	Transcriptional regulator
D0808_RS00220	COG1846	Transcriptional regulator
D0808_RS00225	COG2814	Major facilitator Superfamily
D0808_RS00235	COG3420	alginic acid biosynthetic process
D0808_RS00240	COG1953	Uracil, thiamine, allantoin
D0808_RS00245	COG0477	Major facilitator Superfamily
D0808_RS00250	COG1335	isochorismatase
D0808_RS00260	COG0004	ammonium transporteR
D0808_RS00265	COG0347	Belongs to the P(II) protein family
D0808_RS00270	COG0671	phosphoesterase, PA-phosphatase related
D0808_RS00280	COG0739	heme binding
D0808_RS00285	COG1247	-acetyltransferase
D0808_RS00305	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D0808_RS00310	COG0789	Transcriptional regulator
D0808_RS00320	COG2910	NAD(P)H-binding
D0808_RS00325	COG1959	2 iron, 2 sulfur cluster binding
D0808_RS00330	COG0804	urea catabolic process
D0808_RS00335	COG0832	Belongs to the urease beta subunit family
D0808_RS00340	COG0831	urea catabolic process
D0808_RS00355	COG3237	CsbD-like
D0808_RS00360	COG1994	Peptidase M50
D0808_RS00365	COG0457	Tetratricopeptide repeat
D0808_RS00370	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
D0808_RS00375	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
D0808_RS00385	COG2304	oxidoreductase activity
D0808_RS00395	COG2304	oxidoreductase activity
D0808_RS00400	COG2385	sporulation resulting in formation of a cellular spore
D0808_RS00405	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D0808_RS00415	COG4836	Membrane
D0808_RS00425	COG0355	proton-transporting ATP synthase activity, rotational mechanism
D0808_RS00430	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
D0808_RS00435	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
D0808_RS00440	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
D0808_RS00445	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D0808_RS00450	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
D0808_RS00460	COG0356	it plays a direct role in the translocation of protons across the membrane
D0808_RS00470	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
D0808_RS00475	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
D0808_RS00480	COG4475	Protein of unknown function (DUF436)
D0808_RS00485	COG0698	ribose 5-phosphate isomerase
D0808_RS00490	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D0808_RS00495	COG1971	Probably functions as a manganese efflux pump
D0808_RS00500	COG0009	L-threonylcarbamoyladenylate synthase
D0808_RS00505	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
D0808_RS00525	COG2890	protein-(glutamine-N5) methyltransferase activity
D0808_RS00530	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
D0808_RS00535	COG0346	lactoylglutathione lyase activity
D0808_RS00540	COG0789	Transcriptional regulator
D0808_RS00545	COG0679	Auxin Efflux Carrier
D0808_RS00550	COG0281	malic enzyme
D0808_RS00555	COG1435	thymidine kinase activity
D0808_RS00565	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
D0808_RS00575	COG1494	fructose-1,6-bisphosphatase
D0808_RS00580	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D0808_RS00585	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
D0808_RS00590	COG0191	fructose-bisphosphate aldolase activity
D0808_RS00595	COG2204	response regulator
D0808_RS00600	COG4821	SIS domain
D0808_RS00605	COG0504	CTP synthase activity
D0808_RS00610	COG3343	RNA polymerase activity
D0808_RS00615	COG1960	acyl-CoA dehydrogenase activity
D0808_RS00620	COG2181	nitrate reductase activity
D0808_RS00620	COG0247	lactate metabolic process
D0808_RS00625	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D0808_RS00630	COG4294	response to UV
D0808_RS00640	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D0808_RS00645	COG1132	(ABC) transporter
D0808_RS00650	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D0808_RS00660	COG2181	nitrate reductase activity
D0808_RS00665	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
D0808_RS00670	COG1140	nitrate reductase beta subunit
D0808_RS00675	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
D0808_RS00680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D0808_RS00690	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D0808_RS00695	COG2223	nitrite transmembrane transporter activity
D0808_RS00700	COG0018	arginyl-trna synthetase
D0808_RS00705	COG4506	Protein conserved in bacteria
D0808_RS00720	COG0535	radical SAM domain protein
D0808_RS00730	COG1131	(ABC) transporter
D0808_RS00735	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D0808_RS00740	COG0612	Peptidase, M16
D0808_RS00745	COG0612	Peptidase, M16
D0808_RS00755	COG3391	amine dehydrogenase activity
D0808_RS00760	COG3391	amine dehydrogenase activity
D0808_RS00770	COG0457	Tetratricopeptide repeat
D0808_RS00785	COG0010	Belongs to the arginase family
D0808_RS00790	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
D0808_RS00795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D0808_RS00805	COG1994	Peptidase M50
D0808_RS00810	COG1942	4-Oxalocrotonate Tautomerase
D0808_RS00815	COG1846	Transcriptional regulator
D0808_RS00820	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D0808_RS00825	COG0477	Major facilitator Superfamily
D0808_RS00830	COG1959	2 iron, 2 sulfur cluster binding
D0808_RS00835	COG3465	dGTPase activity
D0808_RS00840	COG1078	dGTPase activity
D0808_RS00845	COG4844	belongs to the
D0808_RS00855	COG0697	spore germination
D0808_RS00860	COG0095	Lipoate-protein ligase
D0808_RS00865	COG0583	DNA-binding transcription factor activity
D0808_RS00870	COG0280	phosphate acetyltransferase
D0808_RS00875	COG3253	May function as heme-dependent peroxidase
D0808_RS00880	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_RS00885	COG0436	Aminotransferase
D0808_RS00890	COG2814	Major facilitator Superfamily
D0808_RS00895	COG0151	Belongs to the GarS family
D0808_RS00900	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_RS00905	COG1917	Cupin 2, conserved barrel domain protein
D0808_RS00910	COG0077	Prephenate dehydratase
D0808_RS00915	COG2814	Major facilitator Superfamily
D0808_RS00920	COG0833	amino acid
D0808_RS00925	COG4187	Peptidase family M20/M25/M40
D0808_RS00930	COG1012	belongs to the aldehyde dehydrogenase family
D0808_RS00935	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D0808_RS00945	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
D0808_RS00950	COG1091	dTDP-4-dehydrorhamnose reductase activity
D0808_RS00955	COG1088	dTDP-glucose 4,6-dehydratase activity
D0808_RS00960	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
D0808_RS00965	COG3980	spore coat polysaccharide biosynthesis protein
D0808_RS00970	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
D0808_RS00975	COG2089	acid synthase
D0808_RS00980	COG0456	acetyltransferase
D0808_RS00985	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D0808_RS00990	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D0808_RS00995	COG0463	Glycosyl transferase, family 2
D0808_RS01005	COG2363	Small membrane protein
D0808_RS01010	COG2233	PERMEase
D0808_RS01020	COG1012	belongs to the aldehyde dehydrogenase family
D0808_RS01025	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
D0808_RS01030	COG1216	Glycosyl transferase, family 2
D0808_RS01045	COG1695	Transcriptional regulator
D0808_RS01050	COG0351	phosphomethylpyrimidine kinase
D0808_RS01060	COG1621	beta-fructofuranosidase activity
D0808_RS01065	COG1263	PTS System
D0808_RS01065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0808_RS01070	COG2116	formate transmembrane transporter activity
D0808_RS01075	COG3711	transcriptional antiterminator
D0808_RS01085	COG1404	Belongs to the peptidase S8 family
D0808_RS01090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D0808_RS01095	COG0778	Nitroreductase
D0808_RS01100	COG0772	Belongs to the SEDS family
D0808_RS01110	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
D0808_RS01115	COG1845	cytochrome c oxidase, subunit III
D0808_RS01120	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D0808_RS01125	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D0808_RS01130	COG2261	transglycosylase associated protein
D0808_RS01135	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
D0808_RS01140	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
D0808_RS01145	COG2246	polysaccharide biosynthetic process
D0808_RS01150	COG1309	transcriptional regulator
D0808_RS01160	COG3162	membrane
D0808_RS01165	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D0808_RS01170	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
D0808_RS01175	COG2837	iron assimilation
D0808_RS01180	COG2822	iron ion transport
D0808_RS01185	COG0672	)-iron permease
D0808_RS01190	COG0352	thiamine-phosphate diphosphorylase activity
D0808_RS01195	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
D0808_RS01200	COG0583	DNA-binding transcription factor activity
D0808_RS01205	COG1380	Effector of murein hydrolase LrgA
D0808_RS01210	COG1346	cytolysis
D0808_RS01215	COG2814	Major facilitator Superfamily
D0808_RS01220	COG4895	conserved protein (DUF2196)
D0808_RS01225	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
D0808_RS01230	COG0346	lactoylglutathione lyase activity
D0808_RS01240	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D0808_RS01245	COG1404	Belongs to the peptidase S8 family
D0808_RS01250	COG1263	PTS System
D0808_RS01250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0808_RS01255	COG3711	transcriptional antiterminator
D0808_RS01260	COG1442	glycosyl transferase family 8
D0808_RS01265	COG5522	Integral membrane protein (intg_mem_TP0381)
D0808_RS01270	COG1846	Transcriptional regulator
D0808_RS01275	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D0808_RS01280	COG2234	aminopeptidase activity
D0808_RS01300	COG2357	RelA SpoT domain protein
D0808_RS01305	COG1575	Belongs to the MenA family. Type 1 subfamily
D0808_RS01320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0808_RS01325	COG1696	Membrane protein involved in D-alanine export
D0808_RS01330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D0808_RS01335	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
D0808_RS01340	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
D0808_RS01345	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D0808_RS01350	COG1486	melibiose metabolic process
D0808_RS01355	COG1447	Phosphotransferase system cellobiose-specific component IIA
D0808_RS01360	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D0808_RS01365	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D0808_RS01370	COG3711	transcriptional antiterminator
D0808_RS01370	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0808_RS01380	COG2094	Belongs to the DNA glycosylase MPG family
D0808_RS01385	COG0753	catalase activity
D0808_RS01395	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D0808_RS01400	COG1131	(ABC) transporter
D0808_RS01420	COG1595	DNA-templated transcription, initiation
D0808_RS01425	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D0808_RS01430	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
D0808_RS01435	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
D0808_RS01440	COG4988	ABC transporter
D0808_RS01445	COG1294	oxidase, subunit
D0808_RS01450	COG1271	oxidase subunit
D0808_RS01455	COG3493	citrate carrier protein
D0808_RS01460	COG0501	Belongs to the peptidase M48B family
D0808_RS01475	COG3842	ATPase activity
D0808_RS01480	COG2508	Transcriptional regulator
D0808_RS01485	COG1012	belongs to the aldehyde dehydrogenase family
D0808_RS01490	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D0808_RS01500	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D0808_RS01510	COG4585	Histidine kinase
D0808_RS01515	COG2197	response regulator
D0808_RS01520	COG2195	Cleaves the N-terminal amino acid of tripeptides
D0808_RS01530	COG4894	glucomannan catabolic process
D0808_RS01535	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D0808_RS01540	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D0808_RS01545	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_RS01550	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D0808_RS01555	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D0808_RS01560	COG2610	gluconate transmembrane transporter activity
D0808_RS01565	COG0500	methyltransferase
D0808_RS01570	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D0808_RS01585	COG0693	protein deglycase activity
D0808_RS01585	COG0753	catalase activity
D0808_RS01590	COG2851	Citrate transporter
D0808_RS01595	COG2273	Hydrolase Family 16
D0808_RS01600	COG3711	transcriptional antiterminator
D0808_RS01610	COG2270	Major facilitator Superfamily
D0808_RS01615	COG0513	Belongs to the DEAD box helicase family
D0808_RS01620	COG2755	lipolytic protein G-D-S-L family
D0808_RS01620	COG3401	FG-GAP repeat protein
D0808_RS01650	COG0697	spore germination
D0808_RS01655	COG0789	Transcriptional regulator
D0808_RS01675	COG0589	response to stress
D0808_RS01680	COG2723	6-phospho-beta-galactosidase activity
D0808_RS01685	COG2190	(PTS) system
D0808_RS01685	COG1263	PTS System
D0808_RS01685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0808_RS01725	COG0494	nUDIX hydrolase
D0808_RS01735	COG3507	Belongs to the glycosyl hydrolase 43 family
D0808_RS01750	COG2986	histidine ammonia-lyase
D0808_RS01755	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
D0808_RS01760	COG1228	amidohydrolase
D0808_RS01765	COG0010	Belongs to the arginase family
D0808_RS01770	COG0833	amino acid
D0808_RS01775	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
D0808_RS01780	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D0808_RS01785	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
D0808_RS01790	COG2390	Transcriptional regulator
D0808_RS01800	COG3192	ethanolamine utilization protein
D0808_RS01805	COG2079	MmgE PrpD family protein
D0808_RS01810	COG1473	amidohydrolase
D0808_RS01815	COG1126	abc transporter atp-binding protein
D0808_RS01820	COG0765	amino acid transport
D0808_RS01825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0808_RS01830	COG0456	acetyltransferase
D0808_RS01835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D0808_RS01845	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
D0808_RS01850	COG0561	phosphatase activity
D0808_RS01880	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D0808_RS01885	COG5294	Protein conserved in bacteria
D0808_RS01890	COG0577	efflux transmembrane transporter activity
D0808_RS01895	COG1136	(ABC) transporter
D0808_RS01900	COG2205	protein histidine kinase activity
D0808_RS01905	COG0745	RESPONSE REGULATOR receiver
D0808_RS01910	COG0191	fructose-bisphosphate aldolase activity
D0808_RS01915	COG1082	Xylose isomerase domain protein TIM barrel
D0808_RS01920	COG1082	Xylose isomerase domain protein TIM barrel
D0808_RS01925	COG0673	inositol 2-dehydrogenase activity
D0808_RS01930	COG2814	Major facilitator Superfamily
D0808_RS01935	COG1082	Xylose isomerase domain protein TIM barrel
D0808_RS01940	COG3962	Belongs to the TPP enzyme family
D0808_RS01945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D0808_RS01955	COG1012	belongs to the aldehyde dehydrogenase family
D0808_RS01960	COG1349	DNA-binding transcription factor activity
D0808_RS01965	COG0667	Aldo Keto reductase
D0808_RS01980	COG2814	Major facilitator Superfamily
D0808_RS01985	COG0326	Molecular chaperone. Has ATPase activity
D0808_RS01995	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_RS02000	COG1309	transcriptional regulator
D0808_RS02005	COG1012	belongs to the aldehyde dehydrogenase family
D0808_RS02010	COG0456	acetyltransferase
D0808_RS02015	COG2850	peptidyl-arginine hydroxylation
D0808_RS02020	COG2226	methyltransferase
D0808_RS02035	COG0367	asparagine synthase
D0808_RS02040	COG2814	Major facilitator Superfamily
D0808_RS02045	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D0808_RS02055	COG1714	RDD family
D0808_RS02060	COG2311	Membrane
D0808_RS02065	COG1917	Cupin 2, conserved barrel domain protein
D0808_RS02070	COG1309	transcriptional regulator
D0808_RS02075	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_RS02080	COG1846	Transcriptional regulator
D0808_RS02085	COG1380	Effector of murein hydrolase LrgA
D0808_RS02090	COG1346	cytolysis
D0808_RS02095	COG5039	Polysaccharide pyruvyl transferase
D0808_RS02100	COG1929	Belongs to the glycerate kinase type-1 family
D0808_RS02105	COG1802	Transcriptional regulator
D0808_RS02110	COG1070	Carbohydrate kinase
D0808_RS02115	COG2610	gluconate transmembrane transporter activity
D0808_RS02120	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D0808_RS02125	COG0450	alkyl hydroperoxide reductase
D0808_RS02130	COG3634	alkyl hydroperoxide reductase activity
D0808_RS02135	COG2723	6-phospho-beta-galactosidase activity
D0808_RS02140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0808_RS02140	COG2190	(PTS) system
D0808_RS02140	COG1263	PTS System
D0808_RS02145	COG2188	Transcriptional regulator
D0808_RS02150	COG1074	ATP-dependent DNA helicase activity
D0808_RS02155	COG0501	Belongs to the peptidase M48B family
D0808_RS02175	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
D0808_RS02190	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
D0808_RS02205	COG1063	alcohol dehydrogenase
D0808_RS02225	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
D0808_RS02230	COG0456	acetyltransferase
D0808_RS02235	COG0457	Tetratricopeptide repeat
D0808_RS02245	COG0010	Belongs to the arginase family
D0808_RS02250	COG0833	amino acid
D0808_RS02255	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D0808_RS02260	COG3829	transcription factor binding
D0808_RS02265	COG5002	protein histidine kinase activity
D0808_RS02270	COG0745	RESPONSE REGULATOR receiver
D0808_RS02285	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D0808_RS02290	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
D0808_RS02295	COG4853	Protein conserved in bacteria
D0808_RS02300	COG4863	YycH protein
D0808_RS02305	COG5002	protein histidine kinase activity
D0808_RS02310	COG0745	RESPONSE REGULATOR receiver
D0808_RS02340	COG0346	lactoylglutathione lyase activity
D0808_RS02345	COG0305	Participates in initiation and elongation during chromosome replication
D0808_RS02360	COG3093	addiction module antidote protein HigA
D0808_RS02365	COG2807	transmembrane transport
D0808_RS02370	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
D0808_RS02375	COG0359	binds to the 23S rRNA
D0808_RS02380	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
D0808_RS02385	COG4241	membrane
D0808_RS02395	COG5577	PFAM Coat F domain
D0808_RS02400	COG1733	regulation of RNA biosynthetic process
D0808_RS02405	COG1227	inorganic diphosphatase activity
D0808_RS02415	COG2271	Major facilitator Superfamily
D0808_RS02420	COG0789	Transcriptional regulator
D0808_RS02420	COG4978	Transcriptional regulator
D0808_RS02430	COG4319	ketosteroid isomerase
D0808_RS02435	COG1357	PFAM Pentapeptide repeats (8 copies)
D0808_RS02440	COG2814	Major facilitator Superfamily
D0808_RS02445	COG0583	DNA-binding transcription factor activity
D0808_RS02450	COG2153	protein acetylation
D0808_RS02460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D0808_RS02465	COG1846	Transcriptional regulator
D0808_RS02470	COG2153	protein acetylation
D0808_RS02475	COG2364	Membrane
D0808_RS02480	COG0456	acetyltransferase
D0808_RS02485	COG2315	Protein conserved in bacteria
D0808_RS02490	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D0808_RS02500	COG2814	Major facilitator Superfamily
D0808_RS02510	COG1331	Highly conserved protein containing a thioredoxin domain
D0808_RS02515	COG1266	CAAX protease self-immunity
D0808_RS02520	COG2814	Major facilitator Superfamily
D0808_RS02520	COG0477	Major facilitator Superfamily
D0808_RS02525	COG0110	maltose O-acetyltransferase activity
D0808_RS02530	COG0346	lactoylglutathione lyase activity
D0808_RS02535	COG1609	Transcriptional regulator
D0808_RS02540	COG0708	Exodeoxyribonuclease III
D0808_RS02545	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
D0808_RS02550	COG0629	single-stranded DNA binding
D0808_RS02555	COG0360	Binds together with S18 to 16S ribosomal RNA
D0808_RS02560	COG0012	GTP binding
D0808_RS02565	COG0243	molybdopterin cofactor binding
D0808_RS02570	COG4481	Protein conserved in bacteria
D0808_RS02575	COG3949	Membrane
D0808_RS02585	COG1475	DNA binding
D0808_RS02590	COG1192	Involved in chromosome partitioning
D0808_RS02600	COG1475	DNA binding
D0808_RS02605	COG0357	Ribosomal RNA small subunit methyltransferase G
D0808_RS02610	COG0445	tRNA wobble uridine modification
D0808_RS02615	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
D0808_RS02620	COG1847	R3H domain protein
D0808_RS02625	COG0706	membrane insertase activity
D0808_RS02630	COG0594	ribonuclease P activity
D0808_RS02640	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
D0808_RS02645	COG0592	DNA-directed DNA polymerase activity
D0808_RS02650	COG2501	S4 domain
D0808_RS02655	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
D0808_RS02665	COG0187	DNA topoisomerase II activity
D0808_RS02670	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D0808_RS02695	COG0517	IMP dehydrogenase activity
D0808_RS02695	COG0516	GMP reductase activity
D0808_RS02700	COG1686	Belongs to the peptidase S11 family
D0808_RS02705	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
D0808_RS02710	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
D0808_RS02715	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
D0808_RS02725	COG1428	Deoxynucleoside kinase
D0808_RS02730	COG1428	Deoxynucleoside kinase
D0808_RS02735	COG3858	chitin binding
D0808_RS02735	COG1388	LysM domain
D0808_RS02740	COG1335	isochorismatase
D0808_RS02745	COG0590	tRNA wobble adenosine to inosine editing
D0808_RS02755	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
D0808_RS02760	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
D0808_RS02765	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
D0808_RS02800	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
D0808_RS02805	COG3853	Toxic anion resistance protein (TelA)
D0808_RS02810	COG1982	Orn Lys Arg decarboxylase major
D0808_RS02815	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
D0808_RS02820	COG3870	Protein conserved in bacteria
D0808_RS02825	COG1728	Protein conserved in bacteria
D0808_RS02830	COG0470	DNA polymerase III
D0808_RS02835	COG1774	PSP1 C-terminal conserved region
D0808_RS02840	COG4467	Involved in initiation control of chromosome replication
D0808_RS02845	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
D0808_RS02850	COG2827	Endonuclease containing a URI domain
D0808_RS02855	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
D0808_RS02860	COG2002	toxin-antitoxin pair type II binding
D0808_RS02865	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D0808_RS02865	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D0808_RS02870	COG0084	hydrolase, TatD family'
D0808_RS02875	COG3583	domain protein
D0808_RS02875	COG3584	3D domain protein
D0808_RS02880	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
D0808_RS02885	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
D0808_RS02895	COG4466	Protein conserved in bacteria
D0808_RS02905	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
D0808_RS02910	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D0808_RS02915	COG0251	oxidation-reduction process
D0808_RS02920	COG2088	sporulation resulting in formation of a cellular spore
D0808_RS02925	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
D0808_RS02930	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
D0808_RS02935	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
D0808_RS02940	COG0193	aminoacyl-tRNA hydrolase activity
D0808_RS02950	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D0808_RS02955	COG2002	toxin-antitoxin pair type II binding
D0808_RS02960	COG2244	polysaccharide biosynthetic process
D0808_RS02965	COG3956	TIGRFAM MazG family protein
D0808_RS02970	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
D0808_RS02985	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
D0808_RS02990	COG1098	S1 RNA binding domain
D0808_RS03005	COG2208	phosphoserine phosphatase activity
D0808_RS03010	COG2304	oxidoreductase activity
D0808_RS03015	COG0515	serine threonine protein kinase
D0808_RS03020	COG0037	tRNA processing
D0808_RS03025	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
D0808_RS03030	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D0808_RS03035	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
D0808_RS03040	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
D0808_RS03045	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D0808_RS03050	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D0808_RS03055	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D0808_RS03060	COG0512	Glutamine amidotransferase of anthranilate synthase
D0808_RS03065	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D0808_RS03070	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
D0808_RS03075	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
D0808_RS03080	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D0808_RS03085	COG1396	sequence-specific DNA binding
D0808_RS03090	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D0808_RS03095	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
D0808_RS03175	COG4463	regulation of RNA biosynthetic process
D0808_RS03180	COG3880	PFAM UvrB UvrC protein
D0808_RS03185	COG3869	Catalyzes the specific phosphorylation of arginine residues in
D0808_RS03190	COG0542	response to heat
D0808_RS03195	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
D0808_RS03200	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
D0808_RS03205	COG4956	integral membrane protein (PIN domain superfamily)
D0808_RS03210	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
D0808_RS03215	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
D0808_RS03220	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D0808_RS03225	COG1045	serine acetyltransferase
D0808_RS03230	COG0215	cysteine-tRNA ligase activity
D0808_RS03235	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
D0808_RS03240	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D0808_RS03245	COG3688	RNA-binding protein containing a PIN domain
D0808_RS03250	COG1595	DNA-templated transcription, initiation
D0808_RS03260	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D0808_RS03265	COG0250	Participates in transcription elongation, termination and antitermination
D0808_RS03275	COG0081	regulation of translation
D0808_RS03280	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
D0808_RS03290	COG2813	Specifically methylates the guanine in position
D0808_RS03295	COG0085	RNA polymerase activity
D0808_RS03300	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
D0808_RS03305	COG1358	cellular component organization or biogenesis
D0808_RS03310	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
D0808_RS03315	COG0049	tRNA binding
D0808_RS03320	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
D0808_RS03325	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
D0808_RS03330	COG0596	Alpha beta hydrolase
D0808_RS03340	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
D0808_RS03345	COG0088	Forms part of the polypeptide exit tunnel
D0808_RS03355	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
D0808_RS03375	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
D0808_RS03385	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
D0808_RS03390	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
D0808_RS03400	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
D0808_RS03410	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
D0808_RS03415	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
D0808_RS03420	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
D0808_RS03425	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
D0808_RS03435	COG0200	Binds to the 23S rRNA
D0808_RS03440	COG0201	protein transport
D0808_RS03445	COG0563	adenylate kinase activity
D0808_RS03450	COG0024	Methionine aminopeptidase
D0808_RS03455	COG2163	COG2163 Ribosomal protein L14E L6E L27E
D0808_RS03465	COG0257	Belongs to the bacterial ribosomal protein bL36 family
D0808_RS03470	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
D0808_RS03475	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
D0808_RS03480	COG0202	RNA polymerase activity
D0808_RS03485	COG0203	ribosomal protein L17
D0808_RS03490	COG1122	ATPase activity
D0808_RS03495	COG1122	ATPase activity
D0808_RS03500	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D0808_RS03505	COG0101	tRNA pseudouridine synthase activity
D0808_RS03510	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
D0808_RS03515	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
D0808_RS03520	COG2226	methyltransferase
D0808_RS03530	COG0860	N-Acetylmuramoyl-L-alanine amidase
D0808_RS03535	COG0489	protein tyrosine kinase activity
D0808_RS03545	COG2194	sulfuric ester hydrolase activity
D0808_RS03550	COG0726	polysaccharide deacetylase
D0808_RS03700	COG0659	secondary active sulfate transmembrane transporter activity
D0808_RS03705	COG0385	Bile acid
D0808_RS03710	COG2819	hydrolase of the alpha beta superfamily
D0808_RS03715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0808_RS03720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0808_RS03725	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D0808_RS03730	COG2207	Transcriptional regulator
D0808_RS03730	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D0808_RS03735	COG3876	Protein conserved in bacteria
D0808_RS03740	COG1472	Belongs to the glycosyl hydrolase 3 family
D0808_RS03745	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D0808_RS03750	COG1263	PTS System
D0808_RS03750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0808_RS03755	COG1737	Transcriptional regulator
D0808_RS03760	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
D0808_RS03765	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D0808_RS03770	COG1683	Conserved Protein
D0808_RS03800	COG1595	DNA-templated transcription, initiation
D0808_RS03805	COG5662	AntiSigma factor
D0808_RS03810	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
D0808_RS03815	COG4856	YbbR-like protein
D0808_RS03820	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D0808_RS03830	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D0808_RS03850	COG0084	hydrolase, TatD family'
D0808_RS03855	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D0808_RS03860	COG3002	Belongs to the UPF0753 family
D0808_RS03865	COG0288	reversible hydration of carbon dioxide
D0808_RS03875	COG5609	conserved protein (DUF2294)
D0808_RS03880	COG0640	Transcriptional regulator
D0808_RS03885	COG2814	Major facilitator Superfamily
D0808_RS03905	COG0596	Alpha beta hydrolase
D0808_RS03910	COG0745	RESPONSE REGULATOR receiver
D0808_RS03915	COG0642	Histidine kinase
D0808_RS03925	COG0515	serine threonine protein kinase
D0808_RS03940	COG1113	amino acid transport
D0808_RS03955	COG2602	Beta-lactamase
D0808_RS03960	COG2124	cytochrome p450
D0808_RS03970	COG0531	amino acid
D0808_RS03975	COG0584	glycerophosphoryl diester phosphodiesterase
D0808_RS03980	COG2271	Major facilitator Superfamily
D0808_RS03990	COG0456	acetyltransferase
D0808_RS03990	COG1846	Transcriptional regulator
D0808_RS03995	COG2271	Major facilitator Superfamily
D0808_RS04005	COG3409	Peptidoglycan-binding domain 1 protein
D0808_RS04010	COG0697	spore germination
D0808_RS04015	COG1917	Cupin 2, conserved barrel domain protein
D0808_RS04015	COG2207	Transcriptional regulator
D0808_RS04020	COG1397	ADP-ribosylglycohydrolase
D0808_RS04025	COG5444	nuclease activity
D0808_RS04030	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
D0808_RS04035	COG3591	Belongs to the peptidase S1B family
D0808_RS04045	COG0596	Alpha beta hydrolase
D0808_RS04050	COG1183	phosphatidylcholine synthase activity
D0808_RS04055	COG0586	Pfam SNARE associated Golgi protein
D0808_RS04060	COG0688	phosphatidylethanolamine metabolic process
D0808_RS04070	COG2312	Erythromycin esterase
D0808_RS04075	COG2207	Transcriptional regulator
D0808_RS04080	COG1054	Belongs to the UPF0176 family
D0808_RS04085	COG1301	dicarboxylic acid transport
D0808_RS04090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0808_RS04090	COG1263	PTS System
D0808_RS04090	COG2190	(PTS) system
D0808_RS04095	COG0363	glucosamine-6-phosphate deaminase activity
D0808_RS04100	COG2188	Transcriptional regulator
D0808_RS04110	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D0808_RS04115	COG0833	amino acid
D0808_RS04120	COG2040	homocysteine
D0808_RS04130	COG1115	amino acid carrier protein
D0808_RS04135	COG2066	Belongs to the glutaminase family
D0808_RS04140	COG4191	Histidine kinase
D0808_RS04145	COG0784	Response regulator, receiver
D0808_RS04150	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D0808_RS04155	COG1012	belongs to the aldehyde dehydrogenase family
D0808_RS04160	COG2271	Major facilitator Superfamily
D0808_RS04165	COG4948	Mandelate Racemase Muconate Lactonizing
D0808_RS04170	COG2186	Transcriptional regulator
D0808_RS04175	COG2721	sulfolactate sulfo-lyase activity
D0808_RS04180	COG3173	Aminoglycoside phosphotransferase
D0808_RS04190	COG0697	spore germination
D0808_RS04195	COG0745	RESPONSE REGULATOR receiver
D0808_RS04200	COG2205	protein histidine kinase activity
D0808_RS04205	COG1131	(ABC) transporter
D0808_RS04225	COG3773	Cell wall hydrolase
D0808_RS04230	COG2304	oxidoreductase activity
D0808_RS04240	COG3540	Alkaline phosphatase
D0808_RS04245	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D0808_RS04250	COG0805	protein transport
D0808_RS04255	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
D0808_RS04260	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D0808_RS04265	COG0477	Major facilitator Superfamily
D0808_RS04270	COG1309	transcriptional regulator
D0808_RS04280	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
D0808_RS04285	COG1714	RDD family
D0808_RS04290	COG3012	SEC-C Motif Domain Protein
D0808_RS04290	COG1405	negative regulation of cell septum assembly
D0808_RS04295	COG3290	protein histidine kinase activity
D0808_RS04300	COG3279	Response regulator of the LytR AlgR family
D0808_RS04305	COG4555	ABC transporter
D0808_RS04310	COG1668	transmembrane transport
D0808_RS04315	COG0667	Aldo Keto reductase
D0808_RS04330	COG1595	DNA-templated transcription, initiation
D0808_RS04335	COG1595	DNA-templated transcription, initiation
D0808_RS04340	COG1876	peptidase activity
D0808_RS04345	COG0457	Tetratricopeptide repeat
D0808_RS04350	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_RS04355	COG0366	Alpha amylase catalytic
D0808_RS04360	COG0803	Belongs to the bacterial solute-binding protein 9 family
D0808_RS04365	COG1121	(ABC) transporter
D0808_RS04370	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D0808_RS04375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D0808_RS04380	COG2310	stress, protein
D0808_RS04385	COG2310	stress, protein
D0808_RS04390	COG2310	stress, protein
D0808_RS04395	COG0861	Integral membrane protein TerC family
D0808_RS04405	COG3853	Toxic anion resistance protein (TelA)
D0808_RS04410	COG0477	Major facilitator Superfamily
D0808_RS04415	COG2814	Major facilitator Superfamily
D0808_RS04420	COG0640	Transcriptional regulator
D0808_RS04425	COG0517	IMP dehydrogenase activity
D0808_RS04425	COG4175	Glycine betaine
D0808_RS04430	COG4176	ABC-type proline glycine betaine transport system permease component
D0808_RS04435	COG2113	Glycine betaine
D0808_RS04440	COG1473	amidohydrolase
D0808_RS04445	COG1288	antiporter activity
D0808_RS04455	COG0366	Alpha amylase catalytic
D0808_RS04460	COG0039	L-malate dehydrogenase activity
D0808_RS04465	COG1620	l-lactate permease
D0808_RS04470	COG2814	Major facilitator Superfamily
D0808_RS04475	COG1846	Transcriptional regulator
D0808_RS04480	COG1280	lysine exporter protein (LysE YggA)
D0808_RS04485	COG3403	YqcI/YcgG family
D0808_RS04490	COG1113	amino acid transport
D0808_RS04495	COG3665	Urea carboxylase-associated protein
D0808_RS04500	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
D0808_RS04505	COG1660	Displays ATPase and GTPase activities
D0808_RS04510	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
D0808_RS04515	COG2226	methyltransferase
D0808_RS04520	COG0583	DNA-binding transcription factor activity
D0808_RS04525	COG3458	cephalosporin-C deacetylase activity
D0808_RS04530	COG3541	Predicted nucleotidyltransferase
D0808_RS04535	COG0506	proline dehydrogenase activity
D0808_RS04540	COG1012	belongs to the aldehyde dehydrogenase family
D0808_RS04545	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D0808_RS04550	COG2508	Transcriptional regulator
D0808_RS04555	COG3689	TIGRFAM TIGR03943 family protein
D0808_RS04560	COG0701	Predicted permease
D0808_RS04565	COG2267	carboxylic ester hydrolase activity
D0808_RS04570	COG0492	ferredoxin-NADP+ reductase activity
D0808_RS04575	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D0808_RS04575	COG1587	Uroporphyrinogen-III synthase
D0808_RS04580	COG2146	nitrite reductase [NAD(P)H] activity
D0808_RS04585	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D0808_RS04590	COG0243	molybdopterin cofactor binding
D0808_RS04595	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D0808_RS04600	COG2223	nitrite transmembrane transporter activity
D0808_RS04605	COG1469	GTP cyclohydrolase I activity
D0808_RS04620	COG0523	cobalamin synthesis protein
D0808_RS04625	COG0765	amino acid transport
D0808_RS04630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0808_RS04640	COG1714	RDD family
D0808_RS04650	COG1846	Transcriptional regulator
D0808_RS04675	COG3209	COG3209 Rhs family protein
D0808_RS04680	COG0840	transmembrane signaling receptor activity
D0808_RS04680	COG3290	protein histidine kinase activity
D0808_RS04685	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
D0808_RS04690	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
D0808_RS04695	COG1733	regulation of RNA biosynthetic process
D0808_RS04700	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0808_RS04705	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0808_RS04710	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0808_RS04715	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
D0808_RS04720	COG2814	Major facilitator Superfamily
D0808_RS04730	COG0697	spore germination
D0808_RS04735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D0808_RS04745	COG2364	Membrane
D0808_RS04750	COG1126	abc transporter atp-binding protein
D0808_RS04755	COG0765	amino acid transport
D0808_RS04760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0808_RS04765	COG0583	DNA-binding transcription factor activity
D0808_RS04770	COG0163	prenyltransferase activity
D0808_RS04775	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
D0808_RS04790	COG0596	Alpha beta hydrolase
D0808_RS04795	COG3104	oligopeptide transport
D0808_RS04800	COG5434	Belongs to the glycosyl hydrolase 28 family
D0808_RS04810	COG0697	spore germination
D0808_RS04820	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D0808_RS04825	COG1136	(ABC) transporter
D0808_RS04830	COG0577	efflux transmembrane transporter activity
D0808_RS04835	COG0745	RESPONSE REGULATOR receiver
D0808_RS04840	COG5002	protein histidine kinase activity
D0808_RS04840	COG3850	Histidine kinase
D0808_RS04845	COG0457	Tetratricopeptide repeat
D0808_RS04865	COG0527	aspartate kinase activity
D0808_RS04870	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0808_RS04875	COG4605	iron ion homeostasis
D0808_RS04880	COG4604	ABC transporter, ATP-binding protein
D0808_RS04885	COG4607	ABC-type enterochelin transport system periplasmic component
D0808_RS04890	COG2814	Major facilitator Superfamily
D0808_RS04895	COG1309	transcriptional regulator
D0808_RS04900	COG0778	Nitroreductase
D0808_RS04905	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
D0808_RS04910	COG0640	Transcriptional regulator
D0808_RS04915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D0808_RS04920	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D0808_RS04925	COG1012	belongs to the aldehyde dehydrogenase family
D0808_RS04930	COG4975	Glucose uptake
D0808_RS04935	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_RS04940	COG4549	nuclear export factor GLE1
D0808_RS04945	COG2372	response to copper ion
D0808_RS04945	COG1276	copper resistance
D0808_RS04950	COG1349	DNA-binding transcription factor activity
D0808_RS04960	COG2213	PTS system mannitol-specific
D0808_RS04965	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0808_RS04970	COG0246	Mannitol dehydrogenase
D0808_RS04975	COG0473	3-isopropylmalate dehydrogenase activity
D0808_RS04980	COG0681	Belongs to the peptidase S26 family
D0808_RS04985	COG0412	Dienelactone hydrolase
D0808_RS04990	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D0808_RS05000	COG0561	phosphatase activity
D0808_RS05005	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
D0808_RS05010	COG1914	H( )-stimulated, divalent metal cation uptake system
D0808_RS05015	COG4336	lyase activity
D0808_RS05020	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
D0808_RS05025	COG1984	allophanate hydrolase subunit 2
D0808_RS05030	COG1414	Transcriptional regulator
D0808_RS05035	COG2755	lipolytic protein G-D-S-L family
D0808_RS05045	COG2329	Antibiotic biosynthesis monooxygenase
D0808_RS05050	COG0768	penicillin binding
D0808_RS05055	COG4989	oxidoreductase activity
D0808_RS05060	COG3711	transcriptional antiterminator
D0808_RS05065	COG0318	PFAM AMP-dependent synthetase and ligase
D0808_RS05070	COG2226	methyltransferase
D0808_RS05075	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_RS05080	COG1917	Cupin 2, conserved barrel domain protein
D0808_RS05085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D0808_RS05090	COG3871	stress protein (general stress protein 26)
D0808_RS05100	COG2814	Major facilitator Superfamily
D0808_RS05105	COG1522	sequence-specific DNA binding
D0808_RS05110	COG0551	DNA topoisomerase type I activity
D0808_RS05110	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D0808_RS05115	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
D0808_RS05120	COG3706	GGDEF domain
D0808_RS05125	COG5298	Protein conserved in bacteria
D0808_RS05130	COG1215	transferase activity, transferring glycosyl groups
D0808_RS05140	COG0531	amino acid
D0808_RS05145	COG0494	nUDIX hydrolase
D0808_RS05150	COG0028	Belongs to the TPP enzyme family
D0808_RS05165	COG1914	H( )-stimulated, divalent metal cation uptake system
D0808_RS05170	COG2261	transglycosylase associated protein
D0808_RS05175	COG4876	unkown
D0808_RS05180	COG2217	Heavy metal translocating P-type atpase
D0808_RS05185	COG3729	General stress protein
D0808_RS05190	COG0662	Cupin 2, conserved barrel domain protein
D0808_RS05195	COG2329	Antibiotic biosynthesis monooxygenase
D0808_RS05200	COG3546	catalase activity
D0808_RS05205	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D0808_RS05210	COG3290	protein histidine kinase activity
D0808_RS05215	COG4565	transcriptional regulatory protein
D0808_RS05220	COG1301	dicarboxylic acid transport
D0808_RS05225	COG0628	permease
D0808_RS05230	COG1131	(ABC) transporter
D0808_RS05235	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D0808_RS05245	COG1960	acyl-CoA dehydrogenase activity
D0808_RS05260	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D0808_RS05265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D0808_RS05270	COG1181	Belongs to the D-alanine--D-alanine ligase family
D0808_RS05275	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D0808_RS05280	COG0513	Belongs to the DEAD box helicase family
D0808_RS05285	COG3402	PFAM membrane-flanked domain
D0808_RS05290	COG3428	Bacterial PH domain
D0808_RS05295	COG0705	Rhomboid family
D0808_RS05300	COG0736	holo-[acyl-carrier-protein] synthase activity
D0808_RS05305	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
D0808_RS05310	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D0808_RS05315	COG0864	Transcriptional regulator
D0808_RS05320	COG2337	Toxic component of a toxin-antitoxin (TA) module
D0808_RS05325	COG1366	Belongs to the anti-sigma-factor antagonist family
D0808_RS05330	COG1366	Belongs to the anti-sigma-factor antagonist family
D0808_RS05335	COG2172	sigma factor antagonist activity
D0808_RS05340	COG2208	phosphoserine phosphatase activity
D0808_RS05345	COG1366	Belongs to the anti-sigma-factor antagonist family
D0808_RS05350	COG2172	sigma factor antagonist activity
D0808_RS05355	COG1191	sigma factor activity
D0808_RS05360	COG2208	phosphoserine phosphatase activity
D0808_RS05375	COG1673	EVE domain
D0808_RS05380	COG1846	Transcriptional regulator
D0808_RS05385	COG2183	response to ionizing radiation
D0808_RS05395	COG3091	SprT-like family
D0808_RS05435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D0808_RS05450	COG1476	TRANSCRIPTIONal
D0808_RS05460	COG3239	Fatty acid desaturase
D0808_RS05470	COG1278	Cold shock
D0808_RS05475	COG1329	Transcriptional regulator
D0808_RS05480	COG0697	spore germination
D0808_RS05485	COG2207	Transcriptional regulator
D0808_RS05485	COG1917	Cupin 2, conserved barrel domain protein
D0808_RS05490	COG0697	spore germination
D0808_RS05495	COG2207	Transcriptional regulator
D0808_RS05495	COG3708	Transcriptional regulator
D0808_RS05500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D0808_RS05505	COG0477	Major facilitator Superfamily
D0808_RS05515	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
D0808_RS05545	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0808_RS05550	COG1309	transcriptional regulator
D0808_RS05555	COG0697	spore germination
D0808_RS05560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D0808_RS05565	COG2030	dehydratase
D0808_RS05570	COG3545	Serine hydrolase
D0808_RS05575	COG1733	regulation of RNA biosynthetic process
D0808_RS05580	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D0808_RS05585	COG1733	regulation of RNA biosynthetic process
D0808_RS05590	COG2249	NAD(P)H dehydrogenase (quinone) activity
D0808_RS05595	COG2814	Major facilitator Superfamily
D0808_RS05600	COG1309	transcriptional regulator
D0808_RS05605	COG0640	Transcriptional regulator
D0808_RS05610	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D0808_RS05620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D0808_RS05625	COG0697	spore germination
D0808_RS05630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D0808_RS05635	COG0076	glutamate decarboxylase activity
D0808_RS05640	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D0808_RS05645	COG0640	Transcriptional regulator
D0808_RS05650	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D0808_RS05665	COG4585	Histidine kinase
D0808_RS05670	COG2197	response regulator
D0808_RS05675	COG2409	Drug exporters of the RND superfamily
D0808_RS05680	COG0596	Alpha beta hydrolase
D0808_RS05685	COG1811	Na channel or pump
D0808_RS05690	COG0789	Transcriptional regulator
D0808_RS05690	COG4978	Transcriptional regulator
D0808_RS05695	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D0808_RS05700	COG0778	Nitroreductase
D0808_RS05705	COG0346	lactoylglutathione lyase activity
D0808_RS05710	COG2259	Doxx family
D0808_RS05715	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D0808_RS05730	COG2323	membrane
D0808_RS05735	COG2323	membrane
D0808_RS05740	COG0071	Belongs to the small heat shock protein (HSP20) family
D0808_RS05755	COG1309	transcriptional regulator
D0808_RS05765	COG0456	acetyltransferase
D0808_RS05770	COG0488	(ABC) transporter
D0808_RS05775	COG1113	amino acid transport
D0808_RS05780	COG2318	DinB family
D0808_RS05785	COG1846	Transcriptional regulator
D0808_RS05790	COG2409	Drug exporters of the RND superfamily
D0808_RS05790	COG1033	growth of symbiont in host cell
D0808_RS05795	COG0778	Nitroreductase
D0808_RS05800	COG1846	Transcriptional regulator
D0808_RS05805	COG2814	Major facilitator Superfamily
D0808_RS05810	COG0730	response to heat
D0808_RS05815	COG1802	Transcriptional regulator
D0808_RS05820	COG3858	chitin binding
D0808_RS05820	COG1388	LysM domain
D0808_RS05825	COG1819	glycosyl
D0808_RS05835	COG1785	Belongs to the alkaline phosphatase family
D0808_RS05840	COG5646	InterPro IPR014922
D0808_RS05850	COG0454	-acetyltransferase
D0808_RS05855	COG1078	dGTPase activity
D0808_RS05860	COG1388	LysM domain
D0808_RS05865	COG2814	Major facilitator Superfamily
D0808_RS05870	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D0808_RS05875	COG1447	Phosphotransferase system cellobiose-specific component IIA
D0808_RS05880	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D0808_RS05885	COG2723	6-phospho-beta-galactosidase activity
D0808_RS05890	COG2188	Transcriptional regulator
D0808_RS05895	COG1940	carbohydrate kinase activity
D0808_RS05900	COG1482	cell wall glycoprotein biosynthetic process
D0808_RS05905	COG4124	Belongs to the glycosyl hydrolase 26 family
D0808_RS05950	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
D0808_RS05955	COG0802	atpase or kinase
D0808_RS05960	COG1214	PFAM Peptidase M22, glycoprotease
D0808_RS05965	COG0456	acetyltransferase
D0808_RS05970	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
D0808_RS05975	COG0488	(ABC) transporter
D0808_RS05980	COG0315	cyclic pyranopterin monophosphate synthase activity
D0808_RS05985	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
D0808_RS05990	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D0808_RS05995	COG0805	protein transport
D0808_RS06005	COG1266	CAAX protease self-immunity
D0808_RS06015	COG0459	protein refolding
D0808_RS06035	COG1073	alpha beta
D0808_RS06040	COG0457	Tetratricopeptide repeat
D0808_RS06045	COG1063	alcohol dehydrogenase
D0808_RS06050	COG2211	Major facilitator Superfamily
D0808_RS06055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D0808_RS06060	COG1842	Phage shock protein A
D0808_RS06065	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D0808_RS06070	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
D0808_RS06075	COG4260	virion core protein, lumpy skin disease virus
D0808_RS06085	COG2814	Major facilitator Superfamily
D0808_RS06090	COG1063	alcohol dehydrogenase
D0808_RS06095	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
D0808_RS06100	COG0823	Involved in the tonB-independent uptake of proteins
D0808_RS06115	COG2267	carboxylic ester hydrolase activity
D0808_RS06125	COG2132	Multicopper oxidase
D0808_RS06130	COG1113	amino acid transport
D0808_RS06140	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D0808_RS06145	COG0714	Associated with various cellular activities
D0808_RS06150	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
D0808_RS06155	COG1305	Transglutaminase-like
D0808_RS06160	COG0518	GMP synthase (glutamine-hydrolyzing) activity
D0808_RS06160	COG0519	Catalyzes the synthesis of GMP from XMP
D0808_RS06175	COG2252	PERMEase
D0808_RS06180	COG3064	Membrane
D0808_RS06190	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
D0808_RS06200	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
D0808_RS06205	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
D0808_RS06210	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
D0808_RS06215	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
D0808_RS06220	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D0808_RS06225	COG0047	phosphoribosylformylglycinamidine synthase activity
D0808_RS06230	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D0808_RS06235	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
D0808_RS06240	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
D0808_RS06245	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
D0808_RS06250	COG0138	bifunctional purine biosynthesis protein purh
D0808_RS06255	COG0151	Belongs to the GarS family
D0808_RS06260	COG1522	sequence-specific DNA binding
D0808_RS06265	COG0531	amino acid
D0808_RS06275	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
D0808_RS06280	COG1470	cell adhesion involved in biofilm formation
D0808_RS06285	COG4496	protein, YerC YecD
D0808_RS06290	COG0069	glutamate synthase activity
D0808_RS06295	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
D0808_RS06300	COG0210	DNA helicase
D0808_RS06305	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
D0808_RS06310	COG4851	CamS sex pheromone cAM373 precursor
D0808_RS06315	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D0808_RS06320	COG1285	pathogenesis
D0808_RS06325	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D0808_RS06330	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D0808_RS06335	COG0154	amidase activity
D0808_RS06340	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D0808_RS06345	COG1309	transcriptional regulator
D0808_RS06350	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D0808_RS06355	COG1597	lipid kinase activity
D0808_RS06360	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D0808_RS06385	COG1131	(ABC) transporter
D0808_RS06405	COG3586	endonuclease activity
D0808_RS06415	COG0457	Tetratricopeptide repeat
D0808_RS06425	COG0217	transcriptional regulatory protein
D0808_RS06435	COG1309	transcriptional regulator
D0808_RS06440	COG3631	Ketosteroid isomerase-related protein
D0808_RS06445	COG0702	epimerase
D0808_RS06460	COG3546	catalase activity
D0808_RS06465	COG0454	-acetyltransferase
D0808_RS06475	COG5578	integral membrane protein
D0808_RS06480	COG2972	Histidine kinase
D0808_RS06485	COG4753	response regulator
D0808_RS06485	COG2207	Transcriptional regulator
D0808_RS06490	COG1653	transport
D0808_RS06495	COG1175	transmembrane transport
D0808_RS06500	COG0395	ABC-type sugar transport system, permease component
D0808_RS06505	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
D0808_RS06510	COG2207	Transcriptional regulator
D0808_RS06515	COG2755	lipolytic protein G-D-S-L family
D0808_RS06525	COG5578	integral membrane protein
D0808_RS06530	COG3401	FG-GAP repeat protein
D0808_RS06535	COG3401	FG-GAP repeat protein
D0808_RS06540	COG2755	lipolytic protein G-D-S-L family
D0808_RS06545	COG1874	Beta-galactosidase
D0808_RS06555	COG1653	transport
D0808_RS06560	COG4209	transmembrane transport
D0808_RS06565	COG0395	ABC-type sugar transport system, permease component
D0808_RS06570	COG1486	melibiose metabolic process
D0808_RS06575	COG2323	membrane
D0808_RS06580	COG2329	Antibiotic biosynthesis monooxygenase
D0808_RS06585	COG0346	lactoylglutathione lyase activity
D0808_RS06600	COG5583	Uncharacterized small protein (DUF2292)
D0808_RS06605	COG0670	Belongs to the BI1 family
D0808_RS06625	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D0808_RS06625	COG2124	cytochrome p450
D0808_RS06630	COG1368	sulfuric ester hydrolase activity
D0808_RS06635	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
D0808_RS06640	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D0808_RS06645	COG1442	glycosyl transferase family 8
D0808_RS06650	COG1216	Glycosyl transferase, family 2
D0808_RS06655	COG1442	glycosyl transferase family 8
D0808_RS06660	COG2223	nitrite transmembrane transporter activity
D0808_RS06665	COG1011	Hydrolase
D0808_RS06670	COG0531	amino acid
D0808_RS06675	COG1012	belongs to the aldehyde dehydrogenase family
D0808_RS06680	COG0840	transmembrane signaling receptor activity
D0808_RS06685	COG0488	(ABC) transporter
D0808_RS06695	COG0789	Transcriptional regulator
D0808_RS06700	COG2814	Major facilitator Superfamily
D0808_RS06715	COG0488	(ABC) transporter
D0808_RS06720	COG0513	Belongs to the DEAD box helicase family
D0808_RS06725	COG0456	acetyltransferase
D0808_RS06730	COG2130	NADP-dependent
D0808_RS06735	COG1120	ATPase activity
D0808_RS06740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0808_RS06745	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0808_RS06750	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
D0808_RS06765	COG3866	Pectate lyase
D0808_RS06770	COG0471	metal ion transport
D0808_RS06775	COG3290	protein histidine kinase activity
D0808_RS06780	COG4565	transcriptional regulatory protein
D0808_RS06785	COG3181	Tripartite tricarboxylate transporter family receptor
D0808_RS06790	COG2851	Citrate transporter
D0808_RS06795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D0808_RS06800	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
D0808_RS06805	COG1254	Belongs to the acylphosphatase family
D0808_RS06810	COG2258	MOSC domain
D0808_RS06830	COG0024	Methionine aminopeptidase
D0808_RS06835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0808_RS06835	COG1263	PTS System
D0808_RS06840	COG1368	sulfuric ester hydrolase activity
D0808_RS06855	COG1115	amino acid carrier protein
D0808_RS06870	COG0697	spore germination
D0808_RS06875	COG1263	PTS System
D0808_RS06875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0808_RS06880	COG0366	Alpha amylase catalytic
D0808_RS06885	COG2188	Transcriptional regulator
D0808_RS06890	COG0778	Nitroreductase
D0808_RS06895	COG0737	Belongs to the 5'-nucleotidase family
D0808_RS06900	COG0693	protein deglycase activity
D0808_RS06905	COG2814	Major facilitator Superfamily
D0808_RS06910	COG4840	Belongs to the UPF0435 family
D0808_RS06915	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D0808_RS06920	COG4980	gas vesicle protein
D0808_RS06925	COG1295	ribonuclease BN
D0808_RS06930	COG0477	Major facilitator Superfamily
D0808_RS06935	COG0387	Pfam Sodium calcium exchanger
D0808_RS06945	COG0668	transmembrane transport
D0808_RS06950	COG0535	radical SAM domain protein
D0808_RS06960	COG0726	polysaccharide deacetylase
D0808_RS06965	COG2084	Dehydrogenase
D0808_RS06970	COG0598	Magnesium transport protein CorA
D0808_RS06975	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
D0808_RS06980	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D0808_RS06990	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D0808_RS06995	COG4637	Psort location Cytoplasmic, score
D0808_RS07005	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D0808_RS07010	COG0022	dehydrogenase e1 component
D0808_RS07015	COG0508	dehydrogenase complex catalyzes the overall conversion of
D0808_RS07020	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D0808_RS07025	COG3284	Transcriptional regulator
D0808_RS07035	COG1742	UPF0060 membrane protein
D0808_RS07060	COG4842	Belongs to the WXG100 family
D0808_RS07065	COG1486	melibiose metabolic process
D0808_RS07070	COG1737	Transcriptional regulator
D0808_RS07075	COG1263	PTS System
D0808_RS07075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0808_RS07080	COG1132	(ABC) transporter
D0808_RS07085	COG1132	(ABC) transporter
D0808_RS07090	COG2259	Doxx family
D0808_RS07095	COG2514	catechol 2,3-dioxygenase activity
D0808_RS07100	COG4585	Histidine kinase
D0808_RS07105	COG2197	response regulator
D0808_RS07110	COG1131	(ABC) transporter
D0808_RS07115	COG1511	domain protein
D0808_RS07115	COG0842	Transport permease protein
D0808_RS07120	COG0842	Transport permease protein
D0808_RS07125	COG1695	Transcriptional regulator
D0808_RS07130	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
D0808_RS07135	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
D0808_RS07140	COG2318	DinB family
D0808_RS07145	COG2814	Major facilitator Superfamily
D0808_RS07150	COG1846	Transcriptional regulator
D0808_RS07155	COG0392	lysyltransferase activity
D0808_RS07155	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
D0808_RS07160	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D0808_RS07165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0808_RS07170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0808_RS07175	COG0384	phenazine biosynthesis protein PhzF
D0808_RS07180	COG0778	Nitroreductase
D0808_RS07195	COG1090	epimerase
D0808_RS07200	COG2137	regulation of response to DNA damage stimulus
D0808_RS07210	COG2814	Major facilitator Superfamily
D0808_RS07225	COG3103	Sh3 type 3 domain protein
D0808_RS07230	COG5658	integral membrane protein
D0808_RS07235	COG0596	Alpha beta hydrolase
D0808_RS07240	COG0463	Glycosyl transferase, family 2
D0808_RS07245	COG4485	Bacterial membrane protein, YfhO
D0808_RS07250	COG1988	membrane-bound metal-dependent
D0808_RS07255	COG1194	a g-specific adenine glycosylase
D0808_RS07265	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_RS07280	COG3557	Belongs to the UPF0374 family
D0808_RS07285	COG1132	(ABC) transporter
D0808_RS07290	COG4129	membrane
D0808_RS07295	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D0808_RS07300	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D0808_RS07305	COG0735	belongs to the Fur family
D0808_RS07415	COG4326	sporulation control protein
D0808_RS07425	COG5577	PFAM Coat F domain
D0808_RS07430	COG3340	Belongs to the peptidase S51 family
D0808_RS07435	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
D0808_RS07440	COG0277	FAD linked oxidase domain protein
D0808_RS07450	COG0753	catalase activity
D0808_RS07455	COG1116	anion transmembrane transporter activity
D0808_RS07460	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D0808_RS07465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D0808_RS07470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D0808_RS07480	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
D0808_RS07490	COG1476	TRANSCRIPTIONal
D0808_RS07500	COG3382	B3 4 domain protein
D0808_RS07505	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D0808_RS07515	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
D0808_RS07520	COG0789	Transcriptional regulator
D0808_RS07525	COG1664	Polymer-forming cytoskeletal
D0808_RS07530	COG1664	Polymer-forming cytoskeletal
D0808_RS07535	COG2766	serine protein kinase
D0808_RS07540	COG2718	Belongs to the UPF0229 family
D0808_RS07545	COG1846	Transcriptional regulator
D0808_RS07550	COG1566	PFAM secretion protein HlyD family protein
D0808_RS07555	COG2814	Major facilitator Superfamily
D0808_RS07560	COG0655	NAD(P)H dehydrogenase (quinone) activity
D0808_RS07580	COG1725	Transcriptional regulator
D0808_RS07585	COG1131	(ABC) transporter
D0808_RS07590	COG1131	(ABC) transporter
D0808_RS07595	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D0808_RS07600	COG1278	Cold shock
D0808_RS07605	COG1464	Belongs to the NlpA lipoprotein family
D0808_RS07610	COG3706	GGDEF domain
D0808_RS07615	COG1823	symporter activity
D0808_RS07635	COG5577	PFAM Coat F domain
D0808_RS07640	COG4085	toxin activity
D0808_RS07640	COG1525	nuclease
D0808_RS07640	COG0737	Belongs to the 5'-nucleotidase family
D0808_RS07645	COG3764	Sortase (surface protein transpeptidase)
D0808_RS07650	COG0564	pseudouridine synthase activity
D0808_RS07660	COG0517	IMP dehydrogenase activity
D0808_RS07665	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D0808_RS07670	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D0808_RS07670	COG3153	acetyltransferase
D0808_RS07675	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D0808_RS07680	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
D0808_RS07685	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
D0808_RS07690	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
D0808_RS07695	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
D0808_RS07700	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D0808_RS07705	COG2203	Gaf domain
D0808_RS07705	COG4585	Histidine kinase
D0808_RS07710	COG2197	response regulator
D0808_RS07715	COG0431	NADPH-dependent FMN reductase
D0808_RS07730	COG0791	NLP P60 protein
D0808_RS07730	COG1388	LysM domain
D0808_RS07735	COG1959	2 iron, 2 sulfur cluster binding
D0808_RS07740	COG0668	transmembrane transport
D0808_RS07745	COG2719	SpoVR family
D0808_RS07750	COG1785	Belongs to the alkaline phosphatase family
D0808_RS07755	COG1388	LysM domain
D0808_RS07755	COG0791	NLP P60 protein
D0808_RS07760	COG0583	DNA-binding transcription factor activity
D0808_RS07765	COG0372	Belongs to the citrate synthase family
D0808_RS07770	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_RS07775	COG0531	amino acid
D0808_RS07780	COG0733	neurotransmitter:sodium symporter activity
D0808_RS07785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D0808_RS07790	COG0456	acetyltransferase
D0808_RS07805	COG1595	DNA-templated transcription, initiation
D0808_RS07810	COG0667	Aldo Keto reductase
D0808_RS07815	COG0204	Acyl-transferase
D0808_RS07820	COG1253	flavin adenine dinucleotide binding
D0808_RS07825	COG0789	Transcriptional regulator
D0808_RS07830	COG0436	Aminotransferase
D0808_RS07835	COG1253	flavin adenine dinucleotide binding
D0808_RS07840	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D0808_RS07845	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D0808_RS07850	COG0584	glycerophosphoryl diester phosphodiesterase
D0808_RS07860	COG0668	transmembrane transport
D0808_RS07865	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
D0808_RS07870	COG0726	polysaccharide deacetylase
D0808_RS07875	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D0808_RS07880	COG1757	Na H antiporter
D0808_RS07885	COG0589	response to stress
D0808_RS07895	COG1132	(ABC) transporter
D0808_RS07900	COG1132	(ABC) transporter
D0808_RS07905	COG0702	epimerase
D0808_RS07925	COG0189	ligase activity
D0808_RS07930	COG0189	ligase activity
D0808_RS07935	COG4399	Belongs to the UPF0754 family
D0808_RS07940	COG3679	Belongs to the UPF0342 family
D0808_RS07945	COG4335	DNA alkylation repair
D0808_RS07950	COG0561	phosphatase activity
D0808_RS07955	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D0808_RS07960	COG0475	glutathione-regulated potassium exporter activity
D0808_RS07965	COG0490	domain, Protein
D0808_RS07975	COG1024	Enoyl-CoA hydratase
D0808_RS07985	COG4152	abc transporter atp-binding protein
D0808_RS07990	COG1668	transmembrane transport
D0808_RS07995	COG0420	3'-5' exonuclease activity
D0808_RS08000	COG4717	serine-type aminopeptidase activity
D0808_RS08005	COG3481	metal-dependent phosphohydrolase, HD sub domain
D0808_RS08015	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D0808_RS08045	COG1846	Transcriptional regulator
D0808_RS08050	COG4980	gas vesicle protein
D0808_RS08065	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
D0808_RS08070	COG0537	adenosine 5'-monophosphoramidase activity
D0808_RS08075	COG1131	(ABC) transporter
D0808_RS08080	COG4473	ABC transporter
D0808_RS08090	COG1473	amidohydrolase
D0808_RS08095	COG3069	C4-dicarboxylate transmembrane transporter activity
D0808_RS08105	COG2329	Antibiotic biosynthesis monooxygenase
D0808_RS08110	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D0808_RS08115	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
D0808_RS08120	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
D0808_RS08125	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
D0808_RS08130	COG1309	transcriptional regulator
D0808_RS08135	COG1511	domain protein
D0808_RS08140	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D0808_RS08145	COG4377	Putative membrane peptidase family (DUF2324)
D0808_RS08155	COG1363	Peptidase, m42
D0808_RS08160	COG4405	Protein conserved in bacteria
D0808_RS08165	COG1301	dicarboxylic acid transport
D0808_RS08175	COG1234	tRNA 3'-trailer cleavage
D0808_RS08180	COG0095	Lipoate-protein ligase
D0808_RS08185	COG0702	epimerase
D0808_RS08190	COG0318	PFAM AMP-dependent synthetase and ligase
D0808_RS08200	COG0501	Belongs to the peptidase M48B family
D0808_RS08205	COG1404	Belongs to the peptidase S8 family
D0808_RS08210	COG0456	acetyltransferase
D0808_RS08215	COG0604	alcohol dehydrogenase
D0808_RS08220	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
D0808_RS08225	COG0406	alpha-ribazole phosphatase activity
D0808_RS08230	COG0183	Belongs to the thiolase family
D0808_RS08235	COG0318	PFAM AMP-dependent synthetase and ligase
D0808_RS08240	COG1268	BioY protein
D0808_RS08245	COG0840	transmembrane signaling receptor activity
D0808_RS08250	COG0723	plastoquinol--plastocyanin reductase activity
D0808_RS08250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D0808_RS08255	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_RS08265	COG4903	ComK protein
D0808_RS08270	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_RS08280	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D0808_RS08295	COG0398	Pfam SNARE associated Golgi protein
D0808_RS08300	COG0681	Belongs to the peptidase S26 family
D0808_RS08305	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D0808_RS08310	COG1846	Transcriptional regulator
D0808_RS08320	COG0738	Major facilitator superfamily
D0808_RS08325	COG0673	inositol 2-dehydrogenase activity
D0808_RS08330	COG0561	phosphatase activity
D0808_RS08335	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D0808_RS08340	COG1609	Transcriptional regulator
D0808_RS08345	COG3180	Ammonia monooxygenase
D0808_RS08350	COG2814	Major facilitator Superfamily
D0808_RS08350	COG0477	Major facilitator Superfamily
D0808_RS08355	COG4533	DNA binding
D0808_RS08365	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
D0808_RS08370	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
D0808_RS08375	COG1074	ATP-dependent DNA helicase activity
D0808_RS08380	COG0420	3'-5' exonuclease activity
D0808_RS08385	COG0419	ATPase involved in DNA repair
D0808_RS08390	COG1403	HNH endonuclease
D0808_RS08430	COG5337	Spore coat protein CotH
D0808_RS08435	COG0179	Fumarylacetoacetate (FAA) hydrolase
D0808_RS08445	COG1404	Belongs to the peptidase S8 family
D0808_RS08455	COG0367	asparagine synthase
D0808_RS08460	COG1562	ergosterol biosynthetic process
D0808_RS08465	COG0534	Mate efflux family protein
D0808_RS08470	COG1917	Cupin 2, conserved barrel domain protein
D0808_RS08470	COG2207	Transcriptional regulator
D0808_RS08475	COG1609	Transcriptional regulator
D0808_RS08480	COG0673	inositol 2-dehydrogenase activity
D0808_RS08485	COG2318	DinB family
D0808_RS08490	COG1279	arginine transmembrane transporter activity
D0808_RS08500	COG1357	PFAM Pentapeptide repeats (8 copies)
D0808_RS08505	COG2267	carboxylic ester hydrolase activity
D0808_RS08510	COG0529	Catalyzes the synthesis of activated sulfate
D0808_RS08515	COG2046	Belongs to the sulfate adenylyltransferase family
D0808_RS08520	COG0175	sulfate reduction
D0808_RS08525	COG2045	Belongs to the ComB family
D0808_RS08530	COG1809	phosphosulfolactate synthase activity
D0808_RS08535	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D0808_RS08540	COG4948	Mandelate Racemase Muconate Lactonizing
D0808_RS08545	COG2814	Major facilitator Superfamily
D0808_RS08550	COG0454	-acetyltransferase
D0808_RS08555	COG2153	protein acetylation
D0808_RS08560	COG0646	methionine synthase
D0808_RS08560	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
D0808_RS08565	COG1666	GTP binding
D0808_RS08570	COG2996	Protein conserved in bacteria
D0808_RS08590	COG1695	Transcriptional regulator
D0808_RS08605	COG3227	Zinc metalloprotease (Elastase)
D0808_RS08610	COG1307	EDD domain protein, DegV family
D0808_RS08615	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D0808_RS08630	COG0561	phosphatase activity
D0808_RS08635	COG1073	alpha beta
D0808_RS08640	COG2151	metal-sulfur cluster biosynthetic enzyme
D0808_RS08650	COG0277	FAD linked oxidase domain protein
D0808_RS08655	COG2271	Major facilitator Superfamily
D0808_RS08660	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
D0808_RS08665	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
D0808_RS08675	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D0808_RS08680	COG0505	Belongs to the CarA family
D0808_RS08685	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D0808_RS08690	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
D0808_RS08705	COG2267	carboxylic ester hydrolase activity
D0808_RS08715	COG1744	ABC transporter substrate-binding protein PnrA-like
D0808_RS08730	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D0808_RS08735	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D0808_RS08740	COG5504	Zn-dependent protease
D0808_RS08745	COG0444	Belongs to the ABC transporter superfamily
D0808_RS08750	COG4608	Belongs to the ABC transporter superfamily
D0808_RS08760	COG0601	transmembrane transport
D0808_RS08765	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D0808_RS08775	COG0180	Tryptophanyl-tRNA synthetase
D0808_RS08780	COG4166	transmembrane transport
D0808_RS08785	COG0601	transmembrane transport
D0808_RS08790	COG0444	Belongs to the ABC transporter superfamily
D0808_RS08795	COG4608	Belongs to the ABC transporter superfamily
D0808_RS08800	COG2814	Major facilitator Superfamily
D0808_RS08805	COG0456	acetyltransferase
D0808_RS08810	COG1393	Belongs to the ArsC family
D0808_RS08815	COG0861	Integral membrane protein TerC family
D0808_RS08825	COG4862	establishment of competence for transformation
D0808_RS08835	COG4469	Competence protein
D0808_RS08840	COG1164	Oligoendopeptidase f
D0808_RS08850	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
D0808_RS08855	COG2346	COG2346, Truncated hemoglobins
D0808_RS08860	COG0741	lytic transglycosylase activity
D0808_RS08865	COG4116	CYTH
D0808_RS08875	COG2357	RelA SpoT domain protein
D0808_RS08880	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D0808_RS08885	COG0564	pseudouridine synthase activity
D0808_RS08890	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
D0808_RS08895	COG0569	domain protein
D0808_RS08895	COG0475	glutathione-regulated potassium exporter activity
D0808_RS08900	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
D0808_RS08905	COG0352	thiamine-phosphate diphosphorylase activity
D0808_RS08910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D0808_RS08915	COG2104	thiamine diphosphate biosynthetic process
D0808_RS08920	COG2022	thiamine diphosphate biosynthetic process
D0808_RS08925	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D0808_RS08930	COG0351	phosphomethylpyrimidine kinase
D0808_RS08935	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
D0808_RS08990	COG0210	DNA helicase
D0808_RS09000	COG2153	protein acetylation
D0808_RS09005	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
D0808_RS09010	COG2382	esterase
D0808_RS09015	COG0626	cystathionine gamma-synthase activity
D0808_RS09020	COG0626	cystathionine gamma-synthase activity
D0808_RS09025	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D0808_RS09030	COG5505	Protein of unknown function (DUF819)
D0808_RS09055	COG5444	nuclease activity
D0808_RS09080	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
D0808_RS09085	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_RS09095	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0808_RS09095	COG3711	transcriptional antiterminator
D0808_RS09100	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0808_RS09100	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0808_RS09100	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0808_RS09105	COG1482	cell wall glycoprotein biosynthetic process
D0808_RS09115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D0808_RS09125	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D0808_RS09140	COG0109	protoheme IX farnesyltransferase activity
D0808_RS09150	COG0726	polysaccharide deacetylase
D0808_RS09165	COG5504	Zn-dependent protease
D0808_RS09170	COG2205	protein histidine kinase activity
D0808_RS09180	COG3383	formate dehydrogenase (NAD+) activity
D0808_RS09185	COG2427	Protein of unknown function (DUF1641)
D0808_RS09195	COG1051	belongs to the nudix hydrolase family
D0808_RS09205	COG2124	cytochrome p450
D0808_RS09210	COG1819	glycosyl
D0808_RS09220	COG1587	Uroporphyrinogen-III synthase
D0808_RS09225	COG0390	transport system, permease component
D0808_RS09230	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D0808_RS09240	COG4297	protein containing double-stranded beta helix domain
D0808_RS09250	COG1252	NADH dehydrogenase
D0808_RS09255	COG1904	glucuronate isomerase
D0808_RS09260	COG2211	Major facilitator Superfamily
D0808_RS09265	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
D0808_RS09270	COG1063	alcohol dehydrogenase
D0808_RS09275	COG1312	Catalyzes the dehydration of D-mannonate
D0808_RS09280	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_RS09285	COG2271	Major facilitator Superfamily
D0808_RS09290	COG1609	Transcriptional regulator
D0808_RS09295	COG0246	Mannitol dehydrogenase
D0808_RS09300	COG2721	sulfolactate sulfo-lyase activity
D0808_RS09305	COG0730	response to heat
D0808_RS09310	COG2318	DinB family
D0808_RS09315	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D0808_RS09320	COG0457	Tetratricopeptide repeat
D0808_RS09330	COG2350	Protein conserved in bacteria
D0808_RS09335	COG5632	N-Acetylmuramoyl-L-alanine amidase
D0808_RS09335	COG3409	Peptidoglycan-binding domain 1 protein
D0808_RS09335	COG1388	LysM domain
D0808_RS09345	COG4195	phage-related replication protein
D0808_RS09350	COG3546	catalase activity
D0808_RS09355	COG2856	Zn peptidase
D0808_RS09360	COG1396	sequence-specific DNA binding
D0808_RS09370	COG1522	sequence-specific DNA binding
D0808_RS09375	COG1484	DNA-dependent DNA replication
D0808_RS09395	COG1595	DNA-templated transcription, initiation
D0808_RS09400	COG5484	DNA packaging
D0808_RS09400	COG3728	DNA packaging
D0808_RS09405	COG1783	phage Terminase large subunit
D0808_RS09410	COG5518	Phage portal protein
D0808_RS09415	COG0338	D12 class N6 adenine-specific DNA methyltransferase
D0808_RS09420	COG4653	Phage capsid family
D0808_RS09470	COG3953	SLT domain
D0808_RS09470	COG5412	phage tail tape measure protein
D0808_RS09475	COG1652	LysM domain
D0808_RS09480	COG4193	domain, Protein
D0808_RS09490	COG3628	GPW Gp25 family protein
D0808_RS09495	COG3299	homolog of phage Mu protein gp47
D0808_RS09500	COG3778	Protein conserved in bacteria
D0808_RS09540	COG3409	Peptidoglycan-binding domain 1 protein
D0808_RS09540	COG5632	N-Acetylmuramoyl-L-alanine amidase
D0808_RS09560	COG0306	phosphate transporter
D0808_RS09565	COG1392	Phosphate transport regulator
D0808_RS09570	COG0531	amino acid
D0808_RS09575	COG0346	lactoylglutathione lyase activity
D0808_RS09585	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
D0808_RS09590	COG0463	Glycosyl transferase, family 2
D0808_RS09595	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D0808_RS09600	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D0808_RS09605	COG2362	D-Aminopeptidase
D0808_RS09610	COG0601	transmembrane transport
D0808_RS09615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D0808_RS09620	COG0444	Belongs to the ABC transporter superfamily
D0808_RS09625	COG4166	transmembrane transport
D0808_RS09630	COG1619	proteins homologs of microcin C7 resistance protein MccF
D0808_RS09635	COG4948	Mandelate Racemase Muconate Lactonizing
D0808_RS09640	COG0791	NLP P60 protein
D0808_RS09645	COG4608	Belongs to the ABC transporter superfamily
D0808_RS09650	COG2706	6-phosphogluconolactonase activity
D0808_RS09655	COG1834	amidinotransferase
D0808_RS09660	COG1607	acyl-coa hydrolase
D0808_RS09665	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D0808_RS09665	COG1017	nitric oxide dioxygenase activity
D0808_RS09675	COG2323	membrane
D0808_RS09680	COG2318	DinB family
D0808_RS09685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D0808_RS09690	COG2076	Multidrug Resistance protein
D0808_RS09695	COG2076	Multidrug Resistance protein
D0808_RS09700	COG0788	formyltetrahydrofolate deformylase activity
D0808_RS09705	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D0808_RS09710	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
D0808_RS09715	COG1764	response to oxidative stress
D0808_RS09720	COG1846	Transcriptional regulator
D0808_RS09725	COG1764	response to oxidative stress
D0808_RS09730	COG0590	tRNA wobble adenosine to inosine editing
D0808_RS09735	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D0808_RS09740	COG1404	Belongs to the peptidase S8 family
D0808_RS09745	COG1366	Belongs to the anti-sigma-factor antagonist family
D0808_RS09750	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D0808_RS09755	COG1122	ATPase activity
D0808_RS09760	COG4721	ABC-type cobalt transport system, permease component
D0808_RS09770	COG0745	RESPONSE REGULATOR receiver
D0808_RS09775	COG3850	Histidine kinase
D0808_RS09775	COG5002	protein histidine kinase activity
D0808_RS09780	COG3212	peptidase
D0808_RS09785	COG3212	peptidase
D0808_RS09795	COG2239	Acts as a magnesium transporter
D0808_RS09800	COG0789	Transcriptional regulator
D0808_RS09815	COG1846	Transcriptional regulator
D0808_RS09820	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D0808_RS09825	COG0726	polysaccharide deacetylase
D0808_RS09830	COG1408	metallophosphoesterase
D0808_RS09840	COG0463	Glycosyl transferase, family 2
D0808_RS09845	COG3285	dna ligase
D0808_RS09845	COG1793	dna ligase
D0808_RS09850	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
D0808_RS09855	COG3300	MHYT domain
D0808_RS09855	COG5001	Diguanylate cyclase
D0808_RS09860	COG0586	Pfam SNARE associated Golgi protein
D0808_RS09865	COG0861	Integral membrane protein TerC family
D0808_RS09870	COG1191	sigma factor activity
D0808_RS09890	COG0501	Belongs to the peptidase M48B family
D0808_RS09895	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D0808_RS09910	COG3594	Acyltransferase
D0808_RS09915	COG5002	protein histidine kinase activity
D0808_RS09920	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D0808_RS09930	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
D0808_RS09935	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
D0808_RS09940	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D0808_RS09945	COG0436	Aminotransferase
D0808_RS09950	COG1850	ribulose-bisphosphate carboxylase activity
D0808_RS09955	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
D0808_RS09960	COG0235	Class ii aldolase
D0808_RS09965	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
D0808_RS09970	COG3339	Conserved Protein
D0808_RS09985	COG3852	Histidine kinase
D0808_RS09990	COG1846	Transcriptional regulator
D0808_RS09995	COG1360	Flagellar Motor Protein
D0808_RS10000	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D0808_RS10005	COG0542	response to heat
D0808_RS10010	COG3949	Membrane
D0808_RS10015	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
D0808_RS10020	COG0720	synthase
D0808_RS10025	COG0602	queuosine metabolic process
D0808_RS10030	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
D0808_RS10035	COG1733	regulation of RNA biosynthetic process
D0808_RS10040	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_RS10045	COG1388	LysM domain
D0808_RS10045	COG4641	Protein conserved in bacteria
D0808_RS10050	COG1388	LysM domain
D0808_RS10055	COG3858	chitin binding
D0808_RS10065	COG4873	Protein conserved in bacteria
D0808_RS10075	COG3773	Cell wall hydrolase
D0808_RS10080	COG2244	polysaccharide biosynthetic process
D0808_RS10085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D0808_RS10090	COG2217	Heavy metal translocating P-type atpase
D0808_RS10100	COG0006	proline dipeptidase activity
D0808_RS10105	COG1609	Transcriptional regulator
D0808_RS10110	COG3711	transcriptional antiterminator
D0808_RS10115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0808_RS10115	COG2190	(PTS) system
D0808_RS10115	COG1263	PTS System
D0808_RS10120	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0808_RS10125	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D0808_RS10135	COG1533	DNA photolyase activity
D0808_RS10140	COG0456	acetyltransferase
D0808_RS10145	COG0840	transmembrane signaling receptor activity
D0808_RS10150	COG2084	Dehydrogenase
D0808_RS10155	COG2340	Cysteine-rich secretory protein family
D0808_RS10160	COG0768	penicillin binding
D0808_RS10165	COG4191	Histidine kinase
D0808_RS10170	COG0436	Aminotransferase
D0808_RS10180	COG0835	chemotaxis
D0808_RS10180	COG0784	Response regulator, receiver
D0808_RS10190	COG2814	Major facilitator Superfamily
D0808_RS10195	COG1376	ErfK ybiS ycfS ynhG family protein
D0808_RS10200	COG1408	metallophosphoesterase
D0808_RS10205	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_RS10210	COG2200	EAL domain
D0808_RS10220	COG4703	Protein of unknown function (DUF1797)
D0808_RS10225	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
D0808_RS10235	COG0517	IMP dehydrogenase activity
D0808_RS10240	COG0583	DNA-binding transcription factor activity
D0808_RS10245	COG0716	FMN binding
D0808_RS10255	COG0716	FMN binding
D0808_RS10260	COG2171	N-acyltransferase activity
D0808_RS10265	COG1473	amidohydrolase
D0808_RS10275	COG0668	transmembrane transport
D0808_RS10280	COG0450	alkyl hydroperoxide reductase
D0808_RS10285	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D0808_RS10300	COG0746	molybdenum cofactor guanylyltransferase activity
D0808_RS10305	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D0808_RS10310	COG0303	'Molybdopterin
D0808_RS10315	COG1763	Mo-molybdopterin cofactor biosynthetic process
D0808_RS10320	COG0314	molybdopterin synthase activity
D0808_RS10325	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
D0808_RS10330	COG1132	(ABC) transporter
D0808_RS10335	COG1132	(ABC) transporter
D0808_RS10345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D0808_RS10350	COG1136	(ABC) transporter
D0808_RS10355	COG0577	efflux transmembrane transporter activity
D0808_RS10360	COG1349	DNA-binding transcription factor activity
D0808_RS10365	COG1105	Belongs to the carbohydrate kinase PfkB family
D0808_RS10370	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0808_RS10370	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0808_RS10370	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0808_RS10375	COG0681	Belongs to the peptidase S26 family
D0808_RS10385	COG0488	(ABC) transporter
D0808_RS10390	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D0808_RS10395	COG2309	aminopeptidase activity
D0808_RS10405	COG1077	Cell shape determining protein MreB Mrl
D0808_RS10410	COG2002	toxin-antitoxin pair type II binding
D0808_RS10415	COG3852	Histidine kinase
D0808_RS10420	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
D0808_RS10420	COG2105	PFAM AIG2 family protein
D0808_RS10425	COG0569	domain protein
D0808_RS10430	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
D0808_RS10435	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D0808_RS10440	COG5503	Protein of unknown function (DUF1447)
D0808_RS10445	COG0561	phosphatase activity
D0808_RS10450	COG0242	peptide deformylase activity
D0808_RS10460	COG0497	DNA recombination
D0808_RS10465	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D0808_RS10470	COG0022	dehydrogenase e1 component
D0808_RS10475	COG0508	dehydrogenase complex catalyzes the overall conversion of
D0808_RS10480	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D0808_RS10485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D0808_RS10495	COG1982	Orn Lys Arg decarboxylase major
D0808_RS10500	COG4476	Belongs to the UPF0223 family
D0808_RS10505	COG4493	Belongs to the UPF0637 family
D0808_RS10515	COG0483	inositol monophosphate 1-phosphatase activity
D0808_RS10525	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
D0808_RS10545	COG1595	DNA-templated transcription, initiation
D0808_RS10565	COG1217	gtp-binding protein TYPA
D0808_RS10575	COG4896	Protein conserved in bacteria
D0808_RS10585	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
D0808_RS10590	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D0808_RS10595	COG2066	Belongs to the glutaminase family
D0808_RS10600	COG4838	Belongs to the UPF0358 family
D0808_RS10605	COG0772	Belongs to the SEDS family
D0808_RS10610	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
D0808_RS10615	COG1612	heme a metabolic process
D0808_RS10620	COG0109	protoheme IX farnesyltransferase activity
D0808_RS10625	COG2010	Cytochrome c
D0808_RS10625	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D0808_RS10630	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D0808_RS10635	COG1845	cytochrome c oxidase, subunit III
D0808_RS10640	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
D0808_RS10645	COG3336	cytochrome c oxidase
D0808_RS10655	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
D0808_RS10660	COG2340	Cysteine-rich secretory protein family
D0808_RS10675	COG3679	Belongs to the UPF0342 family
D0808_RS10680	COG4471	UPF0298 protein
D0808_RS10685	COG0742	ribosomal rna small subunit methyltransferase
D0808_RS10690	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
D0808_RS10695	COG3314	Sporulation integral membrane protein YlbJ
D0808_RS10700	COG1752	Esterase of the alpha-beta hydrolase superfamily
D0808_RS10705	COG3480	Lon protease (S16) C-terminal proteolytic domain
D0808_RS10725	COG1399	metal-binding, possibly nucleic acid-binding protein
D0808_RS10740	COG0454	-acetyltransferase
D0808_RS10745	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D0808_RS10750	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
D0808_RS10755	COG2001	Belongs to the MraZ family
D0808_RS10760	COG0275	rRNA processing
D0808_RS10765	COG4839	cell division protein FtsL
D0808_RS10770	COG0768	penicillin binding
D0808_RS10775	COG0768	penicillin binding
D0808_RS10780	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
D0808_RS10785	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D0808_RS10790	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
D0808_RS10795	COG0772	Belongs to the SEDS family
D0808_RS10800	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D0808_RS10805	COG0812	UDP-N-acetylmuramate dehydrogenase activity
D0808_RS10810	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
D0808_RS10815	COG3879	Bacterial protein of unknown function (DUF881)
D0808_RS10820	COG3879	Bacterial protein of unknown function (DUF881)
D0808_RS10825	COG3856	small basic protein
D0808_RS10830	COG0849	cell division
D0808_RS10835	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
D0808_RS10840	COG4412	M6 family metalloprotease domain protein
D0808_RS10840	COG1404	Belongs to the peptidase S8 family
D0808_RS10850	COG1191	sigma factor activity
D0808_RS10855	COG1191	sigma factor activity
D0808_RS10860	COG1119	ATPase activity
D0808_RS10865	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D0808_RS10870	COG1873	PFAM PRC-barrel domain
D0808_RS10875	COG1496	oxidoreductase activity
D0808_RS10880	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
D0808_RS10885	COG1799	cell septum assembly
D0808_RS10890	COG0762	integral membrane protein
D0808_RS10895	COG2302	S4 RNA-binding domain
D0808_RS10900	COG3599	regulation of cell shape
D0808_RS10905	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
D0808_RS10910	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D0808_RS10915	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
D0808_RS10920	COG0564	pseudouridine synthase activity
D0808_RS10925	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
D0808_RS10930	COG2233	PERMEase
D0808_RS10935	COG0540	Belongs to the ATCase OTCase family
D0808_RS10940	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D0808_RS10945	COG0505	Belongs to the CarA family
D0808_RS10950	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D0808_RS10955	COG0543	2 iron, 2 sulfur cluster binding
D0808_RS10960	COG0167	dihydroorotate dehydrogenase activity
D0808_RS10965	COG0284	orotidine-5'-phosphate decarboxylase activity
D0808_RS10970	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
D0808_RS10975	COG0175	sulfate reduction
D0808_RS10980	COG0306	phosphate transporter
D0808_RS10985	COG2046	Belongs to the sulfate adenylyltransferase family
D0808_RS10990	COG0529	Catalyzes the synthesis of activated sulfate
D0808_RS10995	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D0808_RS11000	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
D0808_RS11005	COG1648	precorrin-2 dehydrogenase activity
D0808_RS11010	COG1293	RNA-binding protein homologous to eukaryotic snRNP
D0808_RS11015	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D0808_RS11020	COG1561	YicC-like family, N-terminal region
D0808_RS11030	COG0194	GDP metabolic process
D0808_RS11035	COG1758	RNA polymerase activity
D0808_RS11040	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D0808_RS11045	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D0808_RS11050	COG0242	peptide deformylase activity
D0808_RS11055	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
D0808_RS11060	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D0808_RS11060	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D0808_RS11065	COG0820	rRNA (adenine-C2-)-methyltransferase activity
D0808_RS11070	COG0631	protein serine/threonine phosphatase activity
D0808_RS11075	COG2815	serine threonine protein kinase
D0808_RS11075	COG0515	serine threonine protein kinase
D0808_RS11080	COG1162	GTPase activity
D0808_RS11085	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D0808_RS11090	COG1564	THIamine pyrophosphokinase
D0808_RS11100	COG0227	Belongs to the bacterial ribosomal protein bL28 family
D0808_RS11105	COG1302	Protein conserved in bacteria
D0808_RS11110	COG1461	Dihydroxyacetone kinase
D0808_RS11115	COG1760	l-serine dehydratase
D0808_RS11120	COG1760	l-serine dehydratase
D0808_RS11125	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D0808_RS11130	COG2050	protein possibly involved in aromatic compounds catabolism
D0808_RS11130	COG1349	DNA-binding transcription factor activity
D0808_RS11135	COG0416	fatty acid biosynthetic process
D0808_RS11140	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D0808_RS11145	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_RS11155	COG0571	ribonuclease III activity
D0808_RS11160	COG1196	nuclear chromosome segregation
D0808_RS11165	COG0552	protein localization to endoplasmic reticulum
D0808_RS11175	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
D0808_RS11180	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D0808_RS11185	COG0228	four-way junction DNA binding
D0808_RS11190	COG1837	Belongs to the UPF0109 family
D0808_RS11200	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
D0808_RS11205	COG0336	Belongs to the RNA methyltransferase TrmD family
D0808_RS11210	COG0335	large ribosomal subunit rRNA binding
D0808_RS11215	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D0808_RS11220	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
D0808_RS11230	COG2257	FlhB HrpN YscU SpaS Family
D0808_RS11235	COG0045	succinate-CoA ligase (ADP-forming) activity
D0808_RS11240	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
D0808_RS11245	COG0758	DNA mediated transformation
D0808_RS11250	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D0808_RS11255	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
D0808_RS11260	COG4974	Belongs to the 'phage' integrase family
D0808_RS11265	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
D0808_RS11270	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
D0808_RS11275	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
D0808_RS11280	COG1815	bacterial-type flagellum-dependent cell motility
D0808_RS11285	COG1558	bacterial-type flagellum-dependent cell motility
D0808_RS11290	COG1677	Flagellar hook-basal body complex protein FliE
D0808_RS11295	COG1766	The M ring may be actively involved in energy transduction
D0808_RS11300	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D0808_RS11305	COG1317	bacterial-type flagellum organization
D0808_RS11310	COG1157	protein secretion by the type III secretion system
D0808_RS11315	COG2882	bacterial-type flagellum organization
D0808_RS11320	COG3334	PFAM MgtE intracellular
D0808_RS11325	COG3144	bacterial-type flagellum assembly
D0808_RS11330	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
D0808_RS11335	COG4786	Flagellar basal body rod
D0808_RS11340	COG1582	Flagellar protein (FlbD)
D0808_RS11345	COG1580	Controls the rotational direction of flagella during chemotaxis
D0808_RS11350	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D0808_RS11355	COG1776	CheC inhibitor of MCP methylation
D0808_RS11355	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D0808_RS11360	COG2201	protein-glutamate methylesterase activity
D0808_RS11365	COG3190	flagellar
D0808_RS11370	COG1338	Plays a role in the flagellum-specific transport system
D0808_RS11375	COG1987	bacterial-type flagellum assembly
D0808_RS11380	COG1684	flagellar biosynthetic protein fliR
D0808_RS11385	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D0808_RS11390	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D0808_RS11395	COG1419	protein localization to endoplasmic reticulum
D0808_RS11400	COG0455	bacterial-type flagellum organization
D0808_RS11405	COG2201	protein-glutamate methylesterase activity
D0808_RS11410	COG2198	Histidine kinase
D0808_RS11410	COG0643	Histidine kinase
D0808_RS11415	COG0835	chemotaxis
D0808_RS11420	COG1776	CheC inhibitor of MCP methylation
D0808_RS11425	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
D0808_RS11430	COG1191	sigma factor activity
D0808_RS11440	COG0052	Belongs to the universal ribosomal protein uS2 family
D0808_RS11445	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
D0808_RS11450	COG0528	UMP kinase activity
D0808_RS11455	COG0233	cytoplasmic translational termination
D0808_RS11460	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
D0808_RS11465	COG4589	Belongs to the CDS family
D0808_RS11470	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
D0808_RS11475	COG0750	zinc metalloprotease
D0808_RS11480	COG0442	prolyl-tRNA aminoacylation
D0808_RS11485	COG2176	DNA-directed DNA polymerase activity
D0808_RS11490	COG0779	Required for maturation of 30S ribosomal subunits
D0808_RS11495	COG0195	Participates in both transcription termination and antitermination
D0808_RS11500	COG2740	Nucleic-acid-binding protein implicated in transcription termination
D0808_RS11505	COG1358	cellular component organization or biogenesis
D0808_RS11510	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
D0808_RS11515	COG1550	Protein conserved in bacteria
D0808_RS11520	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
D0808_RS11525	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
D0808_RS11530	COG0196	riboflavin kinase activity
D0808_RS11535	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
D0808_RS11540	COG1185	polyribonucleotide nucleotidyltransferase activity
D0808_RS11545	COG0726	polysaccharide deacetylase
D0808_RS11550	COG0612	Peptidase, M16
D0808_RS11555	COG1873	PFAM PRC-barrel domain
D0808_RS11560	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D0808_RS11565	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D0808_RS11570	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D0808_RS11575	COG0527	aspartate kinase activity
D0808_RS11580	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D0808_RS11585	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D0808_RS11590	COG0740	serine-type endopeptidase activity
D0808_RS11600	COG1674	ftsk spoiiie
D0808_RS11600	COG4980	gas vesicle protein
D0808_RS11605	COG2188	Transcriptional regulator
D0808_RS11610	COG2814	Major facilitator Superfamily
D0808_RS11615	COG0612	Peptidase, M16
D0808_RS11620	COG0612	Peptidase, M16
D0808_RS11625	COG0300	oxidoreductase activity
D0808_RS11640	COG1426	Protein conserved in bacteria
D0808_RS11645	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D0808_RS11650	COG1546	Belongs to the CinA family
D0808_RS11650	COG1058	Belongs to the CinA family
D0808_RS11655	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
D0808_RS11660	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D0808_RS11665	COG1418	mRNA catabolic process
D0808_RS11670	COG1692	metallophosphoesterase
D0808_RS11675	COG2359	stage V sporulation protein S
D0808_RS11680	COG1063	alcohol dehydrogenase
D0808_RS11685	COG0156	8-amino-7-oxononanoate synthase activity
D0808_RS11690	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D0808_RS11695	COG4550	Control of competence regulator ComK, YlbF/YmcA
D0808_RS11705	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
D0808_RS11710	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
D0808_RS11725	COG3226	Transcriptional regulator
D0808_RS11730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D0808_RS11740	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D0808_RS11745	COG3321	synthase
D0808_RS11750	COG2070	2-Nitropropane dioxygenase
D0808_RS11750	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D0808_RS11755	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D0808_RS11760	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D0808_RS11765	COG3425	synthase
D0808_RS11770	COG1024	Enoyl-CoA hydratase
D0808_RS11775	COG1024	Enoyl-CoA hydratase
D0808_RS11780	COG0300	oxidoreductase activity
D0808_RS11780	COG0318	PFAM AMP-dependent synthetase and ligase
D0808_RS11780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0808_RS11780	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_RS11780	COG3321	synthase
D0808_RS11785	COG3321	synthase
D0808_RS11785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D0808_RS11785	COG4221	oxidoreductase activity
D0808_RS11785	COG0300	oxidoreductase activity
D0808_RS11790	COG3321	synthase
D0808_RS11790	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_RS11790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0808_RS11790	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D0808_RS11790	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D0808_RS11795	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_RS11795	COG3321	synthase
D0808_RS11795	COG4221	oxidoreductase activity
D0808_RS11795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0808_RS11800	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
D0808_RS11800	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D0808_RS11800	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D0808_RS11800	COG3321	synthase
D0808_RS11805	COG2124	cytochrome p450
D0808_RS11815	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D0808_RS11820	COG1404	Belongs to the peptidase S8 family
D0808_RS11830	COG4195	phage-related replication protein
D0808_RS11835	COG1764	response to oxidative stress
D0808_RS11840	COG2076	Multidrug Resistance protein
D0808_RS11845	COG2076	Multidrug Resistance protein
D0808_RS11860	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
D0808_RS11865	COG1923	regulation of RNA biosynthetic process
D0808_RS11880	COG1780	Probably involved in ribonucleotide reductase function
D0808_RS11885	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D0808_RS11890	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D0808_RS11895	COG4112	unkown
D0808_RS11900	COG0860	N-Acetylmuramoyl-L-alanine amidase
D0808_RS11905	COG0464	growth
D0808_RS11910	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D0808_RS11915	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
D0808_RS11920	COG0789	Transcriptional regulator
D0808_RS11925	COG0174	glutamine synthetase
D0808_RS11945	COG4282	regulation of fungal-type cell wall biogenesis
D0808_RS11960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D0808_RS11975	COG3655	Transcriptional regulator
D0808_RS12000	COG0135	phosphoribosylanthranilate isomerase activity
D0808_RS12005	COG2211	Major facilitator Superfamily
D0808_RS12010	COG3507	Belongs to the glycosyl hydrolase 43 family
D0808_RS12015	COG1940	carbohydrate kinase activity
D0808_RS12020	COG2115	Belongs to the xylose isomerase family
D0808_RS12025	COG1070	Carbohydrate kinase
D0808_RS12035	COG1525	nuclease
D0808_RS12040	COG2814	Major facilitator Superfamily
D0808_RS12045	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D0808_RS12055	COG0756	dUTP diphosphatase activity
D0808_RS12070	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
D0808_RS12095	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D0808_RS12110	COG3832	glyoxalase III activity
D0808_RS12120	COG0697	spore germination
D0808_RS12125	COG0531	amino acid
D0808_RS12155	COG4195	phage-related replication protein
D0808_RS12165	COG0346	lactoylglutathione lyase activity
D0808_RS12170	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
D0808_RS12175	COG1388	LysM domain
D0808_RS12180	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D0808_RS12185	COG4224	UPF0291 protein
D0808_RS12190	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D0808_RS12200	COG3763	UPF0154 protein
D0808_RS12210	COG0785	Cytochrome C biogenesis protein
D0808_RS12215	COG2201	protein-glutamate methylesterase activity
D0808_RS12220	COG4846	Membrane protein involved in cytochrome C biogenesis
D0808_RS12230	COG0071	Belongs to the small heat shock protein (HSP20) family
D0808_RS12245	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
D0808_RS12250	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D0808_RS12270	COG0824	Thioesterase
D0808_RS12280	COG4841	protein insertion into membrane
D0808_RS12285	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
D0808_RS12290	COG1832	CoA-binding protein
D0808_RS12295	COG0187	DNA topoisomerase II activity
D0808_RS12300	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D0808_RS12310	COG1115	amino acid carrier protein
D0808_RS12315	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
D0808_RS12325	COG5520	Belongs to the glycosyl hydrolase 30 family
D0808_RS12330	COG3507	Belongs to the glycosyl hydrolase 43 family
D0808_RS12340	COG2246	polysaccharide biosynthetic process
D0808_RS12345	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D0808_RS12350	COG0586	Pfam SNARE associated Golgi protein
D0808_RS12355	COG2404	hydrolase activity, acting on ester bonds
D0808_RS12360	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D0808_RS12365	COG1024	Enoyl-CoA hydratase
D0808_RS12370	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D0808_RS12375	COG0511	ligase activity, forming carbon-carbon bonds
D0808_RS12380	COG0439	Biotin carboxylase
D0808_RS12385	COG0318	PFAM AMP-dependent synthetase and ligase
D0808_RS12390	COG1960	acyl-CoA dehydrogenase activity
D0808_RS12400	COG1649	PFAM Uncharacterised BCR, COG1649
D0808_RS12410	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
D0808_RS12410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0808_RS12420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0808_RS12425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0808_RS12430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0808_RS12435	COG2027	D-alanyl-D-alanine carboxypeptidase
D0808_RS12440	COG2017	converts alpha-aldose to the beta-anomer
D0808_RS12445	COG0534	Mate efflux family protein
D0808_RS12460	COG0582	viral genome integration into host DNA
D0808_RS12465	COG0166	Belongs to the GPI family
D0808_RS12470	COG0405	Gamma-glutamyltransferase
D0808_RS12475	COG0583	DNA-binding transcription factor activity
D0808_RS12480	COG0604	alcohol dehydrogenase
D0808_RS12485	COG0493	'glutamate synthase
D0808_RS12490	COG0070	glutamate synthase
D0808_RS12490	COG0069	glutamate synthase activity
D0808_RS12490	COG0067	glutamate synthase
D0808_RS12495	COG0583	DNA-binding transcription factor activity
D0808_RS12500	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D0808_RS12505	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D0808_RS12515	COG0300	oxidoreductase activity
D0808_RS12520	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
D0808_RS12530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D0808_RS12545	COG1131	(ABC) transporter
D0808_RS12555	COG2814	Major facilitator Superfamily
D0808_RS12560	COG1070	Carbohydrate kinase
D0808_RS12565	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D0808_RS12570	COG0243	molybdopterin cofactor binding
D0808_RS12600	COG2368	4-hydroxyphenylacetate
D0808_RS12605	COG4305	rare lipoprotein A
D0808_RS12610	COG3619	membrane
D0808_RS12615	COG3866	Pectate lyase
D0808_RS12620	COG2135	peptidase activity
D0808_RS12630	COG2140	Oxalate decarboxylase
D0808_RS12660	COG2720	vancomycin resistance protein
D0808_RS12675	COG3739	integral membrane protein
D0808_RS12680	COG0583	DNA-binding transcription factor activity
D0808_RS12685	COG0697	spore germination
D0808_RS12695	COG0693	protein deglycase activity
D0808_RS12700	COG2367	Beta-lactamase
D0808_RS12715	COG3848	Pyruvate phosphate dikinase
D0808_RS12715	COG0574	Belongs to the PEP-utilizing enzyme family
D0808_RS12720	COG0726	polysaccharide deacetylase
D0808_RS12725	COG2314	TM2 domain
D0808_RS12765	COG1231	oxidoreductase activity
D0808_RS12770	COG5434	Belongs to the glycosyl hydrolase 28 family
D0808_RS12775	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D0808_RS12780	COG0662	Cupin 2, conserved barrel domain protein
D0808_RS12780	COG2207	Transcriptional regulator
D0808_RS12785	COG0456	acetyltransferase
D0808_RS12790	COG1309	transcriptional regulator
D0808_RS12795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D0808_RS12800	COG3708	Transcriptional regulator
D0808_RS12805	COG2378	regulation of single-species biofilm formation
D0808_RS12815	COG0640	Transcriptional regulator
D0808_RS12820	COG0741	lytic transglycosylase activity
D0808_RS12825	COG2322	membrane
D0808_RS12840	COG1619	proteins homologs of microcin C7 resistance protein MccF
D0808_RS12845	COG3239	Fatty acid desaturase
D0808_RS12850	COG4585	Histidine kinase
D0808_RS12855	COG2197	response regulator
D0808_RS12860	COG1388	LysM domain
D0808_RS12860	COG3584	3D domain protein
D0808_RS12865	COG0514	ATP-dependent DNA helicase (RecQ)
D0808_RS12875	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D0808_RS12880	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D0808_RS12895	COG0071	Belongs to the small heat shock protein (HSP20) family
D0808_RS12920	COG1012	belongs to the aldehyde dehydrogenase family
D0808_RS12925	COG1657	PFAM Prenyltransferase squalene oxidase
D0808_RS12930	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D0808_RS12935	COG0733	neurotransmitter:sodium symporter activity
D0808_RS12940	COG0385	Bile acid
D0808_RS12945	COG0508	dehydrogenase complex catalyzes the overall conversion of
D0808_RS12950	COG0567	Dehydrogenase, E1 component
D0808_RS12955	COG4548	von Willebrand factor, type A
D0808_RS12960	COG0714	Associated with various cellular activities
D0808_RS12965	COG2032	superoxide dismutase activity
D0808_RS12970	COG1388	LysM domain
D0808_RS12970	COG0791	NLP P60 protein
D0808_RS12975	COG1819	glycosyl
D0808_RS12980	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
D0808_RS12985	COG0534	Mate efflux family protein
D0808_RS12990	COG1366	Belongs to the anti-sigma-factor antagonist family
D0808_RS12995	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D0808_RS13000	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D0808_RS13010	COG2962	Rard protein
D0808_RS13025	COG2610	gluconate transmembrane transporter activity
D0808_RS13030	COG1942	4-Oxalocrotonate Tautomerase
D0808_RS13035	COG1733	regulation of RNA biosynthetic process
D0808_RS13040	COG0778	Nitroreductase
D0808_RS13045	COG0400	carboxylic ester hydrolase activity
D0808_RS13050	COG0346	lactoylglutathione lyase activity
D0808_RS13060	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D0808_RS13065	COG3409	Peptidoglycan-binding domain 1 protein
D0808_RS13065	COG0793	Belongs to the peptidase S41A family
D0808_RS13070	COG2226	methyltransferase
D0808_RS13080	COG1876	peptidase activity
D0808_RS13085	COG0813	purine-nucleoside phosphorylase activity
D0808_RS13100	COG0671	phosphoesterase, PA-phosphatase related
D0808_RS13120	COG4479	Belongs to the UPF0346 family
D0808_RS13130	COG1509	lysine 2,3-aminomutase activity
D0808_RS13135	COG0456	acetyltransferase
D0808_RS13140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D0808_RS13145	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D0808_RS13150	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D0808_RS13155	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D0808_RS13170	COG0456	acetyltransferase
D0808_RS13175	COG0463	Glycosyl transferase, family 2
D0808_RS13190	COG4641	Protein conserved in bacteria
D0808_RS13195	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
D0808_RS13200	COG1086	Polysaccharide biosynthesis protein
D0808_RS13205	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D0808_RS13210	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D0808_RS13215	COG1846	Transcriptional regulator
D0808_RS13220	COG0534	Mate efflux family protein
D0808_RS13230	COG4698	Protein conserved in bacteria
D0808_RS13235	COG2755	lipolytic protein G-D-S-L family
D0808_RS13240	COG1999	signal sequence binding
D0808_RS13250	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D0808_RS13255	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D0808_RS13260	COG1272	protein, Hemolysin III
D0808_RS13265	COG0204	Acyl-transferase
D0808_RS13270	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D0808_RS13275	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
D0808_RS13280	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D0808_RS13290	COG2136	Putative SAM-dependent methyltransferase
D0808_RS13290	COG2521	methyltransferase
D0808_RS13300	COG0129	dihydroxy-acid dehydratase activity
D0808_RS13305	COG1413	lyase activity
D0808_RS13310	COG1418	mRNA catabolic process
D0808_RS13315	COG0386	Belongs to the glutathione peroxidase family
D0808_RS13320	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
D0808_RS13325	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D0808_RS13335	COG1278	Cold shock
D0808_RS13355	COG0328	RNA-DNA hybrid ribonuclease activity
D0808_RS13360	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
D0808_RS13365	COG0328	RNA-DNA hybrid ribonuclease activity
D0808_RS13375	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D0808_RS13390	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D0808_RS13400	COG1755	Isoprenylcysteine carboxyl methyltransferase
D0808_RS13405	COG3424	synthase
D0808_RS13410	COG2233	PERMEase
D0808_RS13415	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D0808_RS13420	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
D0808_RS13430	COG0800	Aldolase
D0808_RS13435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D0808_RS13440	COG1609	Transcriptional regulator
D0808_RS13445	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
D0808_RS13450	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_RS13455	COG1199	ATP-dependent helicase activity
D0808_RS13470	COG0116	Belongs to the methyltransferase superfamily
D0808_RS13485	COG4474	Belongs to the UPF0398 family
D0808_RS13500	COG3359	exonuclease
D0808_RS13505	COG1205	dead DEAH box helicase
D0808_RS13505	COG1111	helicase
D0808_RS13510	COG2190	(PTS) system
D0808_RS13515	COG0071	Belongs to the small heat shock protein (HSP20) family
D0808_RS13550	COG3331	DNA recombination
D0808_RS13555	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D0808_RS13555	COG4499	WXG100 protein secretion system (Wss), protein YukC
D0808_RS13565	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D0808_RS13570	COG3935	DnaD domain protein
D0808_RS13575	COG0017	Asparaginyl-tRNA synthetase
D0808_RS13580	COG0436	Aminotransferase
D0808_RS13585	COG5353	protein conserved in bacteria
D0808_RS13595	COG1199	ATP-dependent helicase activity
D0808_RS13595	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D0808_RS13600	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
D0808_RS13605	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
D0808_RS13610	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
D0808_RS13615	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
D0808_RS13615	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
D0808_RS13620	COG0617	tRNA 3'-terminal CCA addition
D0808_RS13625	COG0438	transferase activity, transferring glycosyl groups
D0808_RS13630	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D0808_RS13635	COG1803	Methylglyoxal synthase
D0808_RS13640	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
D0808_RS13645	COG1694	Mazg nucleotide pyrophosphohydrolase
D0808_RS13650	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D0808_RS13660	COG4347	Protein of unknown function (DUF1405)
D0808_RS13665	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D0808_RS13665	COG2010	Cytochrome c
D0808_RS13670	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D0808_RS13675	COG0723	plastoquinol--plastocyanin reductase activity
D0808_RS13685	COG5582	Belongs to the UPF0302 family
D0808_RS13690	COG0457	Tetratricopeptide repeat
D0808_RS13695	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
D0808_RS13700	COG0287	Prephenate dehydrogenase
D0808_RS13705	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
D0808_RS13710	COG0159	tryptophan synthase activity
D0808_RS13715	COG0133	tryptophan synthase activity
D0808_RS13720	COG0135	phosphoribosylanthranilate isomerase activity
D0808_RS13730	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D0808_RS13735	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D0808_RS13740	COG4401	Chorismate mutase type I
D0808_RS13745	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
D0808_RS13750	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
D0808_RS13755	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
D0808_RS13760	COG0105	UTP biosynthetic process
D0808_RS13765	COG0142	geranyltranstransferase activity
D0808_RS13770	COG2226	methyltransferase
D0808_RS13775	COG0142	geranyltranstransferase activity
D0808_RS13785	COG0302	gtp cyclohydrolase
D0808_RS13790	COG0776	regulation of translation
D0808_RS13795	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D0808_RS13810	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
D0808_RS13815	COG1160	GTP binding
D0808_RS13840	COG1304	FMN binding
D0808_RS13845	COG0539	negative regulation of cytoplasmic translation
D0808_RS13850	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
D0808_RS13860	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
D0808_RS13865	COG2959	enzyme of heme biosynthesis
D0808_RS13870	COG3773	Cell wall hydrolase
D0808_RS13870	COG3409	Peptidoglycan-binding domain 1 protein
D0808_RS13875	COG2339	peptidase activity
D0808_RS13880	COG0492	ferredoxin-NADP+ reductase activity
D0808_RS13885	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D0808_RS13890	COG4862	establishment of competence for transformation
D0808_RS13895	COG1408	metallophosphoesterase
D0808_RS13905	COG1388	LysM domain
D0808_RS13910	COG1266	CAAX protease self-immunity
D0808_RS13915	COG0514	ATP-dependent DNA helicase (RecQ)
D0808_RS13920	COG4955	Helix-turn-helix domain
D0808_RS13925	COG1141	Ferredoxin
D0808_RS13930	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
D0808_RS13935	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D0808_RS13940	COG0710	3-dehydroquinate dehydratase activity
D0808_RS13950	COG1595	DNA-templated transcription, initiation
D0808_RS13955	COG5002	protein histidine kinase activity
D0808_RS13960	COG0745	RESPONSE REGULATOR receiver
D0808_RS13965	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D0808_RS13970	COG1333	cytochrome c biogenesis protein
D0808_RS13975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D0808_RS13980	COG1187	pseudouridine synthase activity
D0808_RS13985	COG0700	Nucleoside recognition
D0808_RS13990	COG2715	membrane protein required for spore maturation
D0808_RS13995	COG1686	Belongs to the peptidase S11 family
D0808_RS14005	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
D0808_RS14010	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
D0808_RS14015	COG1547	Domain of unknown function (DUF309)
D0808_RS14020	COG0456	acetyltransferase
D0808_RS14025	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
D0808_RS14030	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D0808_RS14030	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D0808_RS14035	COG0307	riboflavin synthase, alpha
D0808_RS14040	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D0808_RS14040	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D0808_RS14050	COG0681	Belongs to the peptidase S26 family
D0808_RS14055	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
D0808_RS14095	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D0808_RS14100	COG4086	secreted protein
D0808_RS14105	COG0019	diaminopimelate decarboxylase activity
D0808_RS14110	COG0697	spore germination
D0808_RS14125	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D0808_RS14145	COG1191	sigma factor activity
D0808_RS14150	COG2172	sigma factor antagonist activity
D0808_RS14155	COG1366	Belongs to the anti-sigma-factor antagonist family
D0808_RS14160	COG1686	Belongs to the peptidase S11 family
D0808_RS14165	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
D0808_RS14170	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
D0808_RS14175	COG4974	Belongs to the 'phage' integrase family
D0808_RS14185	COG0735	belongs to the Fur family
D0808_RS14190	COG1300	Membrane
D0808_RS14200	COG0281	malic enzyme
D0808_RS14205	COG1757	Na H antiporter
D0808_RS14210	COG1027	Aspartate ammonia-lyase
D0808_RS14215	COG0252	asparaginase activity
D0808_RS14220	COG1396	sequence-specific DNA binding
D0808_RS14225	COG1379	DNA repair
D0808_RS14230	COG0494	nUDIX hydrolase
D0808_RS14240	COG0667	Aldo Keto reductase
D0808_RS14250	COG1073	alpha beta
D0808_RS14260	COG4918	Iron-sulphur cluster biosynthesis
D0808_RS14265	COG0456	acetyltransferase
D0808_RS14265	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
D0808_RS14270	COG2329	Antibiotic biosynthesis monooxygenase
D0808_RS14275	COG0456	acetyltransferase
D0808_RS14285	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D0808_RS14295	COG2211	Major facilitator Superfamily
D0808_RS14300	COG0346	lactoylglutathione lyase activity
D0808_RS14305	COG1072	(Pantothenic acid kinase))
D0808_RS14310	COG3048	D-serine ammonia-lyase activity
D0808_RS14315	COG0300	oxidoreductase activity
D0808_RS14320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D0808_RS14325	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D0808_RS14330	COG4187	Peptidase family M20/M25/M40
D0808_RS14335	COG1902	pentaerythritol trinitrate reductase activity
D0808_RS14340	COG0596	Alpha beta hydrolase
D0808_RS14350	COG1234	tRNA 3'-trailer cleavage
D0808_RS14355	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
D0808_RS14360	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D0808_RS14365	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D0808_RS14375	COG0706	membrane insertase activity
D0808_RS14380	COG3361	conserved protein (COG2071)
D0808_RS14385	COG2195	Cleaves the N-terminal amino acid of tripeptides
D0808_RS14390	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D0808_RS14395	COG0346	lactoylglutathione lyase activity
D0808_RS14405	COG1376	ErfK ybiS ycfS ynhG family protein
D0808_RS14410	COG4129	membrane
D0808_RS14415	COG1126	abc transporter atp-binding protein
D0808_RS14420	COG0765	amino acid transport
D0808_RS14425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0808_RS14435	COG1597	lipid kinase activity
D0808_RS14440	COG2814	Major facilitator Superfamily
D0808_RS14445	COG0789	Transcriptional regulator
D0808_RS14445	COG4978	Transcriptional regulator
D0808_RS14450	COG0508	dehydrogenase complex catalyzes the overall conversion of
D0808_RS14455	COG0022	dehydrogenase e1 component
D0808_RS14460	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D0808_RS14465	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D0808_RS14470	COG3426	butyrate kinase activity
D0808_RS14475	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D0808_RS14480	COG0280	phosphate acetyltransferase
D0808_RS14485	COG3290	protein histidine kinase activity
D0808_RS14485	COG3829	transcription factor binding
D0808_RS14495	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
D0808_RS14500	COG2079	MmgE PrpD family protein
D0808_RS14505	COG0372	Belongs to the citrate synthase family
D0808_RS14510	COG1960	acyl-CoA dehydrogenase activity
D0808_RS14515	COG1250	3-hydroxyacyl-CoA dehydrogenase
D0808_RS14520	COG0183	Belongs to the thiolase family
D0808_RS14525	COG0584	glycerophosphoryl diester phosphodiesterase
D0808_RS14530	COG0860	N-Acetylmuramoyl-L-alanine amidase
D0808_RS14545	COG1902	pentaerythritol trinitrate reductase activity
D0808_RS14550	COG0745	RESPONSE REGULATOR receiver
D0808_RS14555	COG0750	zinc metalloprotease
D0808_RS14560	COG0497	DNA recombination
D0808_RS14565	COG1438	arginine binding
D0808_RS14570	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
D0808_RS14575	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
D0808_RS14580	COG0142	geranyltranstransferase activity
D0808_RS14585	COG1722	exodeoxyribonuclease VII activity
D0808_RS14590	COG1570	exodeoxyribonuclease VII activity
D0808_RS14595	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
D0808_RS14600	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D0808_RS14605	COG1302	Protein conserved in bacteria
D0808_RS14610	COG0439	Biotin carboxylase
D0808_RS14615	COG0511	ligase activity, forming carbon-carbon bonds
D0808_RS14655	COG3854	ATPases associated with a variety of cellular activities
D0808_RS14665	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
D0808_RS14670	COG0006	proline dipeptidase activity
D0808_RS14675	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
D0808_RS14685	COG3872	metal-dependent enzyme
D0808_RS14695	COG1752	Esterase of the alpha-beta hydrolase superfamily
D0808_RS14700	COG1321	iron dependent repressor
D0808_RS14705	COG0095	Lipoate-protein ligase
D0808_RS14710	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D0808_RS14715	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D0808_RS14720	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D0808_RS14725	COG0404	The glycine cleavage system catalyzes the degradation of glycine
D0808_RS14730	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D0808_RS14745	COG1396	sequence-specific DNA binding
D0808_RS14755	COG0681	Belongs to the peptidase S26 family
D0808_RS14780	COG4940	Competence protein ComGF
D0808_RS14790	COG4970	Tfp pilus assembly protein FimT
D0808_RS14795	COG4537	Required for transformation and DNA binding
D0808_RS14800	COG1459	type II secretion system
D0808_RS14805	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D0808_RS14815	COG0598	Magnesium transport protein CorA
D0808_RS14820	COG1253	flavin adenine dinucleotide binding
D0808_RS14825	COG1366	Belongs to the anti-sigma-factor antagonist family
D0808_RS14835	COG1393	Belongs to the ArsC family
D0808_RS14845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D0808_RS14855	COG0011	TIGRFAM Protein of
D0808_RS14865	COG2866	Carboxypeptidase
D0808_RS14870	COG1368	sulfuric ester hydrolase activity
D0808_RS14875	COG1940	carbohydrate kinase activity
D0808_RS14880	COG4483	Protein conserved in bacteria
D0808_RS14885	COG0457	Tetratricopeptide repeat
D0808_RS14885	COG0705	Rhomboid family
D0808_RS14895	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D0808_RS14905	COG0438	transferase activity, transferring glycosyl groups
D0808_RS14920	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D0808_RS14925	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D0808_RS14930	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D0808_RS14935	COG0581	inorganic phosphate transmembrane transporter activity
D0808_RS14940	COG0573	inorganic phosphate transmembrane transporter activity
D0808_RS14945	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D0808_RS14950	COG0768	penicillin binding
D0808_RS14955	COG0477	Major facilitator Superfamily
D0808_RS14960	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D0808_RS14965	COG2839	Protein conserved in bacteria
D0808_RS14970	COG5521	maltodextrose utilization protein MalA
D0808_RS14975	COG1388	LysM domain
D0808_RS14980	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
D0808_RS14985	COG4709	membrane
D0808_RS14990	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
D0808_RS14995	COG0735	belongs to the Fur family
D0808_RS15000	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D0808_RS15010	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
D0808_RS15015	COG0513	Belongs to the DEAD box helicase family
D0808_RS15025	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
D0808_RS15030	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
D0808_RS15035	COG2384	SAM-dependent methyltransferase
D0808_RS15040	COG2010	Cytochrome c
D0808_RS15045	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D0808_RS15050	COG0358	DNA primase activity
D0808_RS15055	COG1671	Belongs to the UPF0178 family
D0808_RS15060	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
D0808_RS15065	COG0517	IMP dehydrogenase activity
D0808_RS15070	COG0751	glycine-tRNA ligase activity
D0808_RS15075	COG0752	glycyl-tRNA synthetase alpha subunit
D0808_RS15080	COG1381	Involved in DNA repair and RecF pathway recombination
D0808_RS15090	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
D0808_RS15095	COG0295	cytidine deaminase activity
D0808_RS15100	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
D0808_RS15105	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
D0808_RS15110	COG1480	7TM receptor with intracellular HD hydrolase
D0808_RS15115	COG1702	phosphate starvation-inducible protein PhoH
D0808_RS15120	COG0561	phosphatase activity
D0808_RS15135	COG4864	UPF0365 protein
D0808_RS15140	COG1030	water channel activity
D0808_RS15145	COG1610	YqeY-like protein
D0808_RS15155	COG1283	sodium-dependent phosphate transmembrane transporter activity
D0808_RS15160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D0808_RS15165	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D0808_RS15170	COG2264	protein methyltransferase activity
D0808_RS15175	COG0484	heat shock protein binding
D0808_RS15180	COG0443	Heat shock 70 kDa protein
D0808_RS15185	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
D0808_RS15190	COG1420	regulation of RNA biosynthetic process
D0808_RS15195	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D0808_RS15200	COG0481	GTPase activity
D0808_RS15210	COG0860	N-Acetylmuramoyl-L-alanine amidase
D0808_RS15215	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
D0808_RS15220	COG0268	Binds directly to 16S ribosomal RNA
D0808_RS15225	COG1466	dna polymerase III delta subunit
D0808_RS15240	COG0658	competence protein
D0808_RS15240	COG2333	competence protein COMEC
D0808_RS15245	COG2131	deaminase
D0808_RS15250	COG1596	polysaccharide export
D0808_RS15250	COG1555	photosystem II stabilization
D0808_RS15255	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D0808_RS15260	COG2226	methyltransferase
D0808_RS15265	COG0799	negative regulation of ribosome biogenesis
D0808_RS15270	COG1713	HD superfamily hydrolase involved in NAD metabolism
D0808_RS15275	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
D0808_RS15280	COG1534	Rna-binding protein
D0808_RS15285	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D0808_RS15290	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D0808_RS15295	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
D0808_RS15305	COG2755	lipolytic protein G-D-S-L family
D0808_RS15310	COG3409	Peptidoglycan-binding domain 1 protein
D0808_RS15310	COG5632	N-Acetylmuramoyl-L-alanine amidase
D0808_RS15315	COG0398	Pfam SNARE associated Golgi protein
D0808_RS15320	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
D0808_RS15330	COG3209	COG3209 Rhs family protein
D0808_RS15340	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D0808_RS15350	COG1063	alcohol dehydrogenase
D0808_RS15360	COG4221	oxidoreductase activity
D0808_RS15380	COG0702	epimerase
D0808_RS15390	COG0457	Tetratricopeptide repeat
D0808_RS15400	COG5444	nuclease activity
D0808_RS15465	COG3778	Protein conserved in bacteria
D0808_RS15470	COG3299	homolog of phage Mu protein gp47
D0808_RS15475	COG3628	GPW Gp25 family protein
D0808_RS15485	COG4193	domain, Protein
D0808_RS15490	COG1652	LysM domain
D0808_RS15495	COG5280	Phage tail tape measure protein TP901
D0808_RS15495	COG3953	SLT domain
D0808_RS15555	COG4653	Phage capsid family
D0808_RS15560	COG0338	D12 class N6 adenine-specific DNA methyltransferase
D0808_RS15570	COG2369	cell adhesion
D0808_RS15575	COG5518	Phage portal protein
D0808_RS15580	COG1783	phage Terminase large subunit
D0808_RS15585	COG5484	DNA packaging
D0808_RS15605	COG3677	Transposase
D0808_RS15620	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
D0808_RS15630	COG1484	DNA-dependent DNA replication
D0808_RS15635	COG3935	DnaD domain protein
D0808_RS15640	COG3723	Recombinational DNA repair protein, rece pathway
D0808_RS15645	COG5377	YqaJ viral recombinase family
D0808_RS15680	COG3620	sequence-specific DNA binding
D0808_RS15690	COG2856	Zn peptidase
D0808_RS15705	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D0808_RS15715	COG2249	NAD(P)H dehydrogenase (quinone) activity
D0808_RS15725	COG0697	spore germination
D0808_RS15730	COG1802	Transcriptional regulator
D0808_RS15735	COG0730	response to heat
D0808_RS15740	COG0425	Belongs to the sulfur carrier protein TusA family
D0808_RS15745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D0808_RS15745	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D0808_RS15755	COG0425	Belongs to the sulfur carrier protein TusA family
D0808_RS15755	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D0808_RS15765	COG2210	Belongs to the sulfur carrier protein TusA family
D0808_RS15770	COG1937	Protein conserved in bacteria
D0808_RS15775	COG0662	Cupin 2, conserved barrel domain protein
D0808_RS15785	COG0789	Transcriptional regulator
D0808_RS15785	COG4978	Transcriptional regulator
D0808_RS15790	COG2814	Major facilitator Superfamily
D0808_RS15795	COG0456	acetyltransferase
D0808_RS15800	COG1253	flavin adenine dinucleotide binding
D0808_RS15810	COG0697	spore germination
D0808_RS15815	COG0583	DNA-binding transcription factor activity
D0808_RS15820	COG2072	flavoprotein involved in K transport
D0808_RS15825	COG1230	cation diffusion facilitator family transporter
D0808_RS15830	COG1942	4-Oxalocrotonate Tautomerase
D0808_RS15835	COG0583	DNA-binding transcription factor activity
D0808_RS15845	COG1114	Component of the transport system for branched-chain amino acids
D0808_RS15850	COG1687	branched-chain amino acid
D0808_RS15855	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
D0808_RS15860	COG1522	sequence-specific DNA binding
D0808_RS15865	COG2732	(Barnase) inhibitor
D0808_RS15870	COG2124	cytochrome p450
D0808_RS15885	COG1609	Transcriptional regulator
D0808_RS15895	COG1175	transmembrane transport
D0808_RS15900	COG0395	ABC-type sugar transport system, permease component
D0808_RS15920	COG0110	maltose O-acetyltransferase activity
D0808_RS15925	COG1335	isochorismatase
D0808_RS15940	COG2318	DinB family
D0808_RS15950	COG2070	2-Nitropropane dioxygenase
D0808_RS15955	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
D0808_RS15965	COG2186	Transcriptional regulator
D0808_RS15980	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_RS15985	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
D0808_RS15990	COG3959	Transketolase, thiamine diphosphate binding domain
D0808_RS16000	COG0789	Transcriptional regulator
D0808_RS16000	COG4978	Transcriptional regulator
D0808_RS16005	COG2315	Protein conserved in bacteria
D0808_RS16015	COG3443	Belongs to the bacterial solute-binding protein 9 family
D0808_RS16020	COG1595	DNA-templated transcription, initiation
D0808_RS16025	COG0667	Aldo Keto reductase
D0808_RS16030	COG3409	Peptidoglycan-binding domain 1 protein
D0808_RS16035	COG5566	PFAM Mor transcription activator
D0808_RS16040	COG0596	Alpha beta hydrolase
D0808_RS16045	COG4991	sh3 domain protein
D0808_RS16050	COG4991	sh3 domain protein
D0808_RS16060	COG0346	lactoylglutathione lyase activity
D0808_RS16070	COG5577	PFAM Coat F domain
D0808_RS16075	COG1063	alcohol dehydrogenase
D0808_RS16085	COG5577	PFAM Coat F domain
D0808_RS16090	COG0789	Transcriptional regulator
D0808_RS16100	COG1064	alcohol dehydrogenase
D0808_RS16105	COG0693	protein deglycase activity
D0808_RS16110	COG1621	beta-fructofuranosidase activity
D0808_RS16115	COG3716	PTS system mannose fructose sorbose family IID component
D0808_RS16120	COG3715	PTS system
D0808_RS16125	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0808_RS16130	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0808_RS16135	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D0808_RS16135	COG3933	PFAM sigma-54 factor interaction domain-containing protein
D0808_RS16145	COG1113	amino acid transport
D0808_RS16150	COG1280	lysine exporter protein (LysE YggA)
D0808_RS16155	COG1378	Sugar-specific transcriptional regulator TrmB
D0808_RS16160	COG1595	DNA-templated transcription, initiation
D0808_RS16170	COG2755	lipolytic protein G-D-S-L family
D0808_RS16170	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
D0808_RS16180	COG2124	cytochrome p450
D0808_RS16180	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D0808_RS16185	COG1309	transcriptional regulator
D0808_RS16190	COG2226	methyltransferase
D0808_RS16205	COG2116	formate transmembrane transporter activity
D0808_RS16210	COG5609	conserved protein (DUF2294)
D0808_RS16215	COG3383	formate dehydrogenase (NAD+) activity
D0808_RS16220	COG2427	Protein of unknown function (DUF1641)
D0808_RS16230	COG0626	cystathionine gamma-synthase activity
D0808_RS16235	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D0808_RS16240	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
D0808_RS16245	COG2226	methyltransferase
D0808_RS16260	COG0768	penicillin binding
D0808_RS16265	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D0808_RS16270	COG0572	uridine kinase
D0808_RS16275	COG0826	peptidase U32
D0808_RS16280	COG0826	peptidase U32
D0808_RS16285	COG4122	O-methyltransferase activity
D0808_RS16290	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D0808_RS16295	COG3906	Belongs to the UPF0473 family
D0808_RS16300	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
D0808_RS16305	COG4472	Bacterial protein of unknown function (DUF965)
D0808_RS16310	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
D0808_RS16315	COG0628	permease
D0808_RS16320	COG1126	abc transporter atp-binding protein
D0808_RS16325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0808_RS16330	COG0765	amino acid transport
D0808_RS16335	COG0765	amino acid transport
D0808_RS16350	COG3881	PFAM PRC-barrel domain
D0808_RS16355	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D0808_RS16360	COG0457	Tetratricopeptide repeat
D0808_RS16365	COG0482	sulfurtransferase activity
D0808_RS16370	COG1104	cysteine desulfurase activity
D0808_RS16375	COG1959	2 iron, 2 sulfur cluster binding
D0808_RS16380	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D0808_RS16385	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
D0808_RS16395	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
D0808_RS16400	COG0124	histidyl-tRNA synthetase
D0808_RS16410	COG0860	N-Acetylmuramoyl-L-alanine amidase
D0808_RS16410	COG3103	Sh3 type 3 domain protein
D0808_RS16410	COG4991	sh3 domain protein
D0808_RS16415	COG1490	D-aminoacyl-tRNA deacylase activity
D0808_RS16420	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D0808_RS16425	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D0808_RS16430	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D0808_RS16430	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
D0808_RS16435	COG5416	Lipopolysaccharide assembly protein A domain
D0808_RS16440	COG0490	domain, Protein
D0808_RS16445	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D0808_RS16445	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D0808_RS16455	COG2244	polysaccharide biosynthetic process
D0808_RS16460	COG2323	membrane
D0808_RS16470	COG1862	Preprotein translocase
D0808_RS16475	COG0343	queuine tRNA-ribosyltransferase activity
D0808_RS16480	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
D0808_RS16490	COG2255	four-way junction helicase activity
D0808_RS16495	COG0632	four-way junction helicase activity
D0808_RS16505	COG2814	Major facilitator Superfamily
D0808_RS16510	COG0673	inositol 2-dehydrogenase activity
D0808_RS16515	COG2112	serine threonine protein kinase
D0808_RS16535	COG1115	amino acid carrier protein
D0808_RS16540	COG0217	transcriptional regulatory protein
D0808_RS16550	COG1388	LysM domain
D0808_RS16555	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
D0808_RS16560	COG0157	Belongs to the NadC ModD family
D0808_RS16565	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
D0808_RS16570	COG1104	cysteine desulfurase activity
D0808_RS16575	COG1827	regulation of RNA biosynthetic process
D0808_RS16580	COG0077	Prephenate dehydratase
D0808_RS16585	COG4492	Belongs to the UPF0735 family
D0808_RS16590	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
D0808_RS16595	COG3290	protein histidine kinase activity
D0808_RS16605	COG0211	Belongs to the bacterial ribosomal protein bL27 family
D0808_RS16610	COG2868	ribosomal protein
D0808_RS16615	COG0261	This protein binds to 23S rRNA in the presence of protein L20
D0808_RS16620	COG1994	Peptidase M50
D0808_RS16625	COG0739	heme binding
D0808_RS16630	COG2894	cell division
D0808_RS16635	COG0850	regulation of cytokinetic process
D0808_RS16640	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
D0808_RS16650	COG1077	Cell shape determining protein MreB Mrl
D0808_RS16655	COG2003	Belongs to the UPF0758 family
D0808_RS16660	COG0424	maF-like protein
D0808_RS16670	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
D0808_RS16675	COG0285	dihydrofolate synthase activity
D0808_RS16680	COG0525	valine-tRNA ligase activity
D0808_RS16690	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D0808_RS16695	COG1388	LysM domain
D0808_RS16700	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D0808_RS16705	COG0113	porphobilinogen synthase activity
D0808_RS16710	COG1587	Uroporphyrinogen-III synthase
D0808_RS16715	COG0181	hydroxymethylbilane synthase activity
D0808_RS16720	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D0808_RS16725	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
D0808_RS16735	COG0218	Necessary for normal cell division and for the maintenance of normal septation
D0808_RS16740	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
D0808_RS16745	COG1067	ATP-dependent peptidase activity
D0808_RS16745	COG0470	DNA polymerase III
D0808_RS16750	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
D0808_RS16755	COG0544	peptidyl-prolyl cis-trans isomerase activity
D0808_RS16760	COG1477	protein flavinylation
D0808_RS16760	COG0457	Tetratricopeptide repeat
D0808_RS16765	COG0066	3-isopropylmalate dehydratase activity
D0808_RS16770	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
D0808_RS16775	COG0473	3-isopropylmalate dehydrogenase activity
D0808_RS16780	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D0808_RS16785	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
D0808_RS16790	COG0440	acetolactate synthase activity
D0808_RS16795	COG0028	Belongs to the TPP enzyme family
D0808_RS16805	COG0454	-acetyltransferase
D0808_RS16815	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
D0808_RS16825	COG0622	Phosphoesterase
D0808_RS16830	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
D0808_RS16835	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
D0808_RS16840	COG5401	PFAM Sporulation and spore germination
D0808_RS16845	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
D0808_RS16850	COG1846	Transcriptional regulator
D0808_RS16855	COG2197	response regulator
D0808_RS16860	COG0824	Thioesterase
D0808_RS16865	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D0808_RS16870	COG1053	succinate dehydrogenase
D0808_RS16875	COG2009	succinate dehydrogenase
D0808_RS16880	COG1719	4-vinyl reductase, 4VR
D0808_RS16885	COG0527	aspartate kinase activity
D0808_RS16890	COG0322	excinuclease ABC activity
D0808_RS16895	COG3118	belongs to the thioredoxin family
D0808_RS16900	COG3534	alpha-L-arabinofuranosidase
D0808_RS16905	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
D0808_RS16910	COG2086	electron transfer activity
D0808_RS16915	COG1024	Enoyl-CoA hydratase
D0808_RS16920	COG1309	transcriptional regulator
D0808_RS16925	COG0318	PFAM AMP-dependent synthetase and ligase
D0808_RS16930	COG3766	membrane
D0808_RS16935	COG1193	negative regulation of DNA recombination
D0808_RS16940	COG1796	DNA polymerase
D0808_RS16940	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D0808_RS16945	COG1286	toxin biosynthetic process
D0808_RS16950	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
D0808_RS16955	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
D0808_RS16960	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D0808_RS16960	COG0072	phenylalanine-tRNA ligase activity
D0808_RS16965	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
D0808_RS16975	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D0808_RS16985	COG3835	regulator
D0808_RS16990	COG0277	FAD linked oxidase domain protein
D0808_RS16995	COG0247	lactate metabolic process
D0808_RS17000	COG0346	lactoylglutathione lyase activity
D0808_RS17010	COG1966	Carbon starvation protein
D0808_RS17015	COG3534	alpha-L-arabinofuranosidase
D0808_RS17020	COG0395	ABC-type sugar transport system, permease component
D0808_RS17025	COG1175	transmembrane transport
D0808_RS17030	COG1653	transport
D0808_RS17035	COG0371	Dehydrogenase
D0808_RS17040	COG0647	UMP catabolic process
D0808_RS17045	COG0235	Class ii aldolase
D0808_RS17050	COG1069	ribulokinase activity
D0808_RS17055	COG2160	L-arabinose isomerase activity
D0808_RS17060	COG3507	Belongs to the glycosyl hydrolase 43 family
D0808_RS17065	COG1363	Peptidase, m42
D0808_RS17075	COG3326	Membrane
D0808_RS17080	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
D0808_RS17085	COG0291	Belongs to the bacterial ribosomal protein bL35 family
D0808_RS17090	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
D0808_RS17100	COG1346	cytolysis
D0808_RS17105	COG1380	Effector of murein hydrolase LrgA
D0808_RS17110	COG3279	Response regulator of the LytR AlgR family
D0808_RS17115	COG3275	phosphorelay sensor kinase activity
D0808_RS17120	COG1011	Hydrolase
D0808_RS17125	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D0808_RS17135	COG0398	Pfam SNARE associated Golgi protein
D0808_RS17140	COG1484	DNA-dependent DNA replication
D0808_RS17145	COG3611	Membrane attachment protein
D0808_RS17150	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
D0808_RS17155	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
D0808_RS17160	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D0808_RS17165	COG1733	regulation of RNA biosynthetic process
D0808_RS17170	COG2814	Major facilitator Superfamily
D0808_RS17175	COG0656	L-ascorbic acid biosynthetic process
D0808_RS17180	COG0237	dephospho-CoA kinase activity
D0808_RS17185	COG1971	Probably functions as a manganese efflux pump
D0808_RS17190	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D0808_RS17195	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D0808_RS17195	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D0808_RS17200	COG5002	protein histidine kinase activity
D0808_RS17205	COG0745	RESPONSE REGULATOR receiver
D0808_RS17210	COG0039	L-malate dehydrogenase activity
D0808_RS17215	COG0538	isocitrate dehydrogenase activity
D0808_RS17220	COG0372	Belongs to the citrate synthase family
D0808_RS17225	COG2707	UPF0756 membrane protein
D0808_RS17230	COG0628	permease
D0808_RS17235	COG3030	protein affecting phage T7 exclusion by the F plasmid
D0808_RS17240	COG0469	pyruvate kinase activity
D0808_RS17245	COG0205	6-phosphofructokinase activity
D0808_RS17250	COG0825	malonyl-CoA metabolic process
D0808_RS17255	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
D0808_RS17260	COG0281	malic enzyme
D0808_RS17265	COG0587	DNA-directed DNA polymerase activity
D0808_RS17285	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
D0808_RS17295	COG4109	DRTGG domain
D0808_RS17300	COG0730	response to heat
D0808_RS17305	COG1473	amidohydrolase
D0808_RS17310	COG0196	riboflavin kinase activity
D0808_RS17315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D0808_RS17320	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
D0808_RS17325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D0808_RS17330	COG1126	abc transporter atp-binding protein
D0808_RS17335	COG0765	amino acid transport
D0808_RS17340	COG0765	amino acid transport
D0808_RS17345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0808_RS17350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0808_RS17355	COG0454	-acetyltransferase
D0808_RS17360	COG0583	DNA-binding transcription factor activity
D0808_RS17365	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
D0808_RS17370	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_RS17380	COG0165	Argininosuccinate lyase
D0808_RS17385	COG0137	argininosuccinate synthase activity
D0808_RS17390	COG0521	Mo-molybdopterin cofactor biosynthetic process
D0808_RS17395	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
D0808_RS17405	COG0827	DNA restriction-modification system
D0808_RS17410	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
D0808_RS17415	COG3874	Sporulation protein YtfJ
D0808_RS17425	COG1714	RDD family
D0808_RS17430	COG0616	signal peptide processing
D0808_RS17435	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D0808_RS17440	COG1574	metal-dependent hydrolase with the TIM-barrel fold
D0808_RS17445	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D0808_RS17455	COG0301	tRNA thio-modification
D0808_RS17460	COG1104	cysteine desulfurase activity
D0808_RS17465	COG1114	Component of the transport system for branched-chain amino acids
D0808_RS17470	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
D0808_RS17475	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D0808_RS17480	COG1309	transcriptional regulator
D0808_RS17485	COG1956	GAF domain-containing protein
D0808_RS17490	COG2199	diguanylate cyclase activity
D0808_RS17490	COG2203	Gaf domain
D0808_RS17500	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
D0808_RS17505	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D0808_RS17510	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D0808_RS17515	COG0454	-acetyltransferase
D0808_RS17520	COG0517	IMP dehydrogenase activity
D0808_RS17525	COG0123	including yeast histone deacetylase and acetoin utilization protein
D0808_RS17530	COG1360	Flagellar Motor Protein
D0808_RS17535	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D0808_RS17540	COG1609	Transcriptional regulator
D0808_RS17545	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
D0808_RS17545	COG1605	Chorismate mutase
D0808_RS17550	COG3118	belongs to the thioredoxin family
D0808_RS17555	COG4980	gas vesicle protein
D0808_RS17560	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
D0808_RS17565	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
D0808_RS17570	COG1674	ftsk spoiiie
D0808_RS17575	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D0808_RS17580	COG4848	Belongs to the UPF0354 family
D0808_RS17585	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D0808_RS17600	COG1363	Peptidase, m42
D0808_RS17605	COG5584	Small secreted protein
D0808_RS17610	COG0281	malic enzyme
D0808_RS17615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D0808_RS17620	COG0220	tRNA (guanine-N7-)-methyltransferase activity
D0808_RS17630	COG0510	thiamine kinase activity
D0808_RS17635	COG1523	belongs to the glycosyl hydrolase 13 family
D0808_RS17640	COG1597	lipid kinase activity
D0808_RS17650	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
D0808_RS17655	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D0808_RS17660	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D0808_RS17665	COG2252	PERMEase
D0808_RS17670	COG4473	ABC transporter
D0808_RS17675	COG1131	(ABC) transporter
D0808_RS17680	COG1349	DNA-binding transcription factor activity
D0808_RS17685	COG1187	pseudouridine synthase activity
D0808_RS17690	COG2244	polysaccharide biosynthetic process
D0808_RS17695	COG2081	HI0933 family
D0808_RS17700	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D0808_RS17710	COG5578	integral membrane protein
D0808_RS17715	COG0673	inositol 2-dehydrogenase activity
D0808_RS17720	COG1653	transport
D0808_RS17725	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
D0808_RS17730	COG4209	transmembrane transport
D0808_RS17735	COG2207	Transcriptional regulator
D0808_RS17740	COG1653	transport
D0808_RS17745	COG0395	ABC-type sugar transport system, permease component
D0808_RS17750	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D0808_RS17755	COG2124	cytochrome p450
D0808_RS17760	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
D0808_RS17770	COG0156	8-amino-7-oxononanoate synthase activity
D0808_RS17775	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D0808_RS17785	COG1073	alpha beta
D0808_RS17790	COG1609	Transcriptional regulator
D0808_RS17795	COG1653	transport
D0808_RS17800	COG1175	transmembrane transport
D0808_RS17805	COG0395	ABC-type sugar transport system, permease component
D0808_RS17810	COG1486	melibiose metabolic process
D0808_RS17815	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D0808_RS17820	COG0495	leucyl-tRNA aminoacylation
D0808_RS17830	COG2202	Pas domain
D0808_RS17830	COG1366	Belongs to the anti-sigma-factor antagonist family
D0808_RS17835	COG2814	Major facilitator Superfamily
D0808_RS17840	COG2433	Pfam Transposase IS66
D0808_RS17845	COG0577	efflux transmembrane transporter activity
D0808_RS17850	COG1136	(ABC) transporter
D0808_RS17855	COG2205	protein histidine kinase activity
D0808_RS17860	COG0745	RESPONSE REGULATOR receiver
D0808_RS17865	COG0577	efflux transmembrane transporter activity
D0808_RS17870	COG1136	(ABC) transporter
D0808_RS17885	COG1131	(ABC) transporter
D0808_RS17890	COG1725	Transcriptional regulator
D0808_RS17905	COG1242	4 iron, 4 sulfur cluster binding
D0808_RS17910	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
D0808_RS17920	COG2267	carboxylic ester hydrolase activity
D0808_RS17925	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D0808_RS17930	COG1113	amino acid transport
D0808_RS17935	COG0367	asparagine synthase
D0808_RS17940	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
D0808_RS17945	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
D0808_RS17955	COG1506	peptidase
D0808_RS17960	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D0808_RS17965	COG1116	anion transmembrane transporter activity
D0808_RS17970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D0808_RS17975	COG0494	nUDIX hydrolase
D0808_RS17980	COG4824	toxin secretion phage lysis holin
D0808_RS17985	COG0783	Belongs to the Dps family
D0808_RS18000	COG1854	S-ribosylhomocysteine lyase activity
D0808_RS18005	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
D0808_RS18010	COG0288	reversible hydration of carbon dioxide
D0808_RS18015	COG0254	rRNA binding
D0808_RS18020	COG1271	oxidase subunit
D0808_RS18025	COG1294	oxidase, subunit
D0808_RS18035	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D0808_RS18040	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D0808_RS18040	COG1321	iron dependent repressor
D0808_RS18045	COG1121	(ABC) transporter
D0808_RS18050	COG0803	Belongs to the bacterial solute-binding protein 9 family
D0808_RS18055	COG4948	Mandelate Racemase Muconate Lactonizing
D0808_RS18060	COG0318	PFAM AMP-dependent synthetase and ligase
D0808_RS18065	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
D0808_RS18070	COG0596	Alpha beta hydrolase
D0808_RS18075	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
D0808_RS18080	COG1169	isochorismate synthase
D0808_RS18085	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D0808_RS18090	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D0808_RS18095	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D0808_RS18100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D0808_RS18105	COG0438	transferase activity, transferring glycosyl groups
D0808_RS18115	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D0808_RS18120	COG0438	transferase activity, transferring glycosyl groups
D0808_RS18125	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D0808_RS18130	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
D0808_RS18135	COG0058	SHG alpha-glucan phosphorylase activity
D0808_RS18140	COG0297	glycogen (starch) synthase activity
D0808_RS18145	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D0808_RS18150	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D0808_RS18155	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
D0808_RS18280	COG3859	Proton-coupled thiamine transporter YuaJ
D0808_RS18285	COG1247	-acetyltransferase
D0808_RS18290	COG2268	Band 7 protein
D0808_RS18295	COG1585	Membrane protein implicated in regulation of membrane protease activity
D0808_RS18300	COG2318	DinB family
D0808_RS18310	COG1454	alcohol dehydrogenase
D0808_RS18315	COG1012	belongs to the aldehyde dehydrogenase family
D0808_RS18320	COG1510	regulation of RNA biosynthetic process
D0808_RS18330	COG0569	domain protein
D0808_RS18335	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D0808_RS18340	COG4682	membrane
D0808_RS18345	COG1705	Flagellar rod assembly protein muramidase FlgJ
D0808_RS18350	COG0477	Major facilitator Superfamily
D0808_RS18355	COG5553	Cysteine dioxygenase type I
D0808_RS18365	COG1968	undecaprenyl-diphosphatase activity
D0808_RS18370	COG0628	permease
D0808_RS18375	COG0673	inositol 2-dehydrogenase activity
D0808_RS18380	COG4806	L-rhamnose isomerase
D0808_RS18385	COG3254	rhamnose metabolic process
D0808_RS18390	COG1070	Carbohydrate kinase
D0808_RS18395	COG1349	DNA-binding transcription factor activity
D0808_RS18400	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_RS18400	COG3347	Dehydrogenase
D0808_RS18405	COG0840	transmembrane signaling receptor activity
D0808_RS18410	COG0840	transmembrane signaling receptor activity
D0808_RS18415	COG0840	transmembrane signaling receptor activity
D0808_RS18420	COG0840	transmembrane signaling receptor activity
D0808_RS18435	COG0432	Pfam Uncharacterised protein family UPF0047
D0808_RS18445	COG0366	Alpha amylase catalytic
D0808_RS18450	COG1253	flavin adenine dinucleotide binding
D0808_RS18455	COG2738	Putative neutral zinc metallopeptidase
D0808_RS18470	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D0808_RS18485	COG0166	Belongs to the GPI family
D0808_RS18490	COG1979	alcohol dehydrogenase
D0808_RS18495	COG1979	alcohol dehydrogenase
D0808_RS18500	COG2155	Conserved Protein
D0808_RS18505	COG1098	S1 RNA binding domain
D0808_RS18510	COG0436	Aminotransferase
D0808_RS18515	COG1522	sequence-specific DNA binding
D0808_RS18520	COG2267	carboxylic ester hydrolase activity
D0808_RS18530	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
D0808_RS18535	COG2205	protein histidine kinase activity
D0808_RS18545	COG5018	Exonuclease
D0808_RS18555	COG2814	Major facilitator Superfamily
D0808_RS18560	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D0808_RS18565	COG3011	Protein conserved in bacteria
D0808_RS18575	COG3290	protein histidine kinase activity
D0808_RS18580	COG4565	transcriptional regulatory protein
D0808_RS18585	COG1744	ABC transporter substrate-binding protein PnrA-like
D0808_RS18590	COG3845	ABC transporter
D0808_RS18600	COG1079	Belongs to the binding-protein-dependent transport system permease family
D0808_RS18605	COG3493	citrate carrier protein
D0808_RS18615	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D0808_RS18615	COG2111	Na H antiporter
D0808_RS18620	COG2111	Na H antiporter
D0808_RS18625	COG1006	Multisubunit Na H antiporter MnhC subunit
D0808_RS18630	COG0651	ATP synthesis coupled electron transport
D0808_RS18635	COG1863	multisubunit Na H antiporter MnhE subunit
D0808_RS18640	COG2212	antiporter activity
D0808_RS18645	COG1320	monovalent cation:proton antiporter activity
D0808_RS18650	COG2050	protein possibly involved in aromatic compounds catabolism
D0808_RS18655	COG2197	response regulator
D0808_RS18660	COG4585	Histidine kinase
D0808_RS18670	COG0142	geranyltranstransferase activity
D0808_RS18685	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
D0808_RS18690	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
D0808_RS18695	COG1335	isochorismatase
D0808_RS18700	COG5506	Protein of unknown function (DUF1694)
D0808_RS18715	COG0628	permease
D0808_RS18730	COG1418	mRNA catabolic process
D0808_RS18735	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_RS18745	COG1511	domain protein
D0808_RS18750	COG1674	ftsk spoiiie
D0808_RS18750	COG0433	COG0433 Predicted ATPase
D0808_RS18755	COG4499	WXG100 protein secretion system (Wss), protein YukC
D0808_RS18760	COG5417	Belongs to the EsaB family
D0808_RS18765	COG4842	Belongs to the WXG100 family
D0808_RS18770	COG2508	Transcriptional regulator
D0808_RS18770	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
D0808_RS18775	COG0686	Belongs to the AlaDH PNT family
D0808_RS18780	COG5634	Uncharacterized conserved protein (DUF2278)
D0808_RS18785	COG3251	PFAM MbtH domain protein
D0808_RS18790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0808_RS18795	COG1535	isochorismatase
D0808_RS18795	COG3433	isochorismatase activity
D0808_RS18800	COG1021	2,3-dihydroxybenzoate-AMP ligase
D0808_RS18805	COG1169	isochorismate synthase
D0808_RS18810	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_RS18815	COG2819	hydrolase of the alpha beta superfamily
D0808_RS18820	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D0808_RS18825	COG1268	BioY protein
D0808_RS18830	COG2056	Na+-H+ antiporter family
D0808_RS18835	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
D0808_RS18840	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
D0808_RS18845	COG3584	3D domain protein
D0808_RS18860	COG1252	NADH dehydrogenase
D0808_RS18865	COG0492	ferredoxin-NADP+ reductase activity
D0808_RS18875	COG0516	GMP reductase activity
D0808_RS18880	COG2808	Putative FMN-binding domain
D0808_RS18885	COG0456	acetyltransferase
D0808_RS18890	COG0316	Belongs to the HesB IscA family
D0808_RS18895	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
D0808_RS18900	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D0808_RS18905	COG4844	belongs to the
D0808_RS18910	COG1252	NADH dehydrogenase
D0808_RS18915	COG4837	Protein of unknown function (DUF1462)
D0808_RS18920	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
D0808_RS18925	COG0823	Involved in the tonB-independent uptake of proteins
D0808_RS18925	COG1506	peptidase
D0808_RS18925	COG4946	Tricorn protease homolog
D0808_RS18930	COG0083	homoserine kinase activity
D0808_RS18935	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
D0808_RS18940	COG0460	homoserine dehydrogenase
D0808_RS18945	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D0808_RS18950	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D0808_RS18955	COG0647	UMP catabolic process
D0808_RS18960	COG2445	Protein of unknown function DUF86
D0808_RS18965	COG4470	Protein conserved in bacteria
D0808_RS18975	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
D0808_RS18980	COG0739	heme binding
D0808_RS18990	COG3377	Domain of unknown function (DUF1805)
D0808_RS18995	COG0737	Belongs to the 5'-nucleotidase family
D0808_RS19000	COG0730	response to heat
D0808_RS19005	COG1801	Protein of unknown function DUF72
D0808_RS19015	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D0808_RS19020	COG2508	Transcriptional regulator
D0808_RS19025	COG2233	PERMEase
D0808_RS19030	COG2233	PERMEase
D0808_RS19035	COG3648	Uricase
D0808_RS19035	COG3195	allantoin biosynthetic process
D0808_RS19040	COG2351	hydroxyisourate hydrolase activity
D0808_RS19050	COG2080	2 iron, 2 sulfur cluster binding
D0808_RS19055	COG1529	Aldehyde oxidase and xanthine dehydrogenase
D0808_RS19060	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
D0808_RS19065	COG2068	MobA-Related Protein
D0808_RS19070	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
D0808_RS19075	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
D0808_RS19080	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D0808_RS19090	COG2356	endonuclease I
D0808_RS19095	COG3842	ATPase activity
D0808_RS19100	COG2188	Transcriptional regulator
D0808_RS19105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D0808_RS19110	COG0395	ABC-type sugar transport system, permease component
D0808_RS19115	COG1175	transmembrane transport
D0808_RS19120	COG1653	transport
D0808_RS19125	COG2222	sugar isomerase
D0808_RS19130	COG0322	excinuclease ABC activity
D0808_RS19135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D0808_RS19150	COG0346	lactoylglutathione lyase activity
D0808_RS19155	COG0640	Transcriptional regulator
D0808_RS19160	COG0719	Fe-S assembly protein
D0808_RS19165	COG0822	iron-sulfur transferase activity
D0808_RS19170	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D0808_RS19175	COG0719	Fe-S assembly protein
D0808_RS19180	COG0396	ATPase activity
D0808_RS19190	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D0808_RS19195	COG1464	Belongs to the NlpA lipoprotein family
D0808_RS19200	COG2011	ABC-type metal ion transport system permease component
D0808_RS19205	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D0808_RS19215	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D0808_RS19220	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
D0808_RS19230	COG0509	glycine decarboxylation via glycine cleavage system
D0808_RS19235	COG1393	Belongs to the ArsC family
D0808_RS19240	COG1960	acyl-CoA dehydrogenase activity
D0808_RS19245	COG0183	Belongs to the thiolase family
D0808_RS19250	COG1250	3-hydroxyacyl-CoA dehydrogenase
D0808_RS19250	COG1024	Enoyl-CoA hydratase
D0808_RS19270	COG5577	PFAM Coat F domain
D0808_RS19280	COG0477	Major facilitator Superfamily
D0808_RS19285	COG1942	4-Oxalocrotonate Tautomerase
D0808_RS19290	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_RS19295	COG0583	DNA-binding transcription factor activity
D0808_RS19305	COG1120	ATPase activity
D0808_RS19320	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_RS19325	COG0783	Belongs to the Dps family
D0808_RS19330	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D0808_RS19335	COG0745	RESPONSE REGULATOR receiver
D0808_RS19340	COG2770	Histidine kinase
D0808_RS19340	COG2205	protein histidine kinase activity
D0808_RS19350	COG1309	transcriptional regulator
D0808_RS19355	COG0114	fumarate hydratase activity
D0808_RS19365	COG0697	spore germination
D0808_RS19370	COG0814	amino acid
D0808_RS19380	COG2197	response regulator
D0808_RS19385	COG4585	Histidine kinase
D0808_RS19390	COG4758	membrane
D0808_RS19395	COG3595	metallopeptidase activity
D0808_RS19400	COG1842	Phage shock protein A
D0808_RS19405	COG4758	membrane
D0808_RS19410	COG2814	Major facilitator Superfamily
D0808_RS19415	COG2096	Adenosyltransferase
D0808_RS19420	COG1120	ATPase activity
D0808_RS19425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0808_RS19430	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D0808_RS19435	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_RS19440	COG3386	PFAM SMP-30 Gluconolaconase
D0808_RS19445	COG2205	protein histidine kinase activity
D0808_RS19450	COG0745	RESPONSE REGULATOR receiver
D0808_RS19460	COG1191	sigma factor activity
D0808_RS19470	COG2140	Oxalate decarboxylase
D0808_RS19480	COG0577	efflux transmembrane transporter activity
D0808_RS19485	COG1136	(ABC) transporter
D0808_RS19490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D0808_RS19495	COG1120	ATPase activity
D0808_RS19500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0808_RS19505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0808_RS19510	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D0808_RS19515	COG0531	amino acid
D0808_RS19525	COG1988	membrane-bound metal-dependent
D0808_RS19530	COG1368	sulfuric ester hydrolase activity
D0808_RS19535	COG1910	domain protein
D0808_RS19540	COG0725	ABC transporter, periplasmic molybdate-binding protein
D0808_RS19545	COG4149	molybdate abc transporter
D0808_RS19550	COG0656	L-ascorbic acid biosynthetic process
D0808_RS19560	COG0025	NhaP-type Na H and K H
D0808_RS19565	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D0808_RS19570	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D0808_RS19575	COG3973	AAA domain
D0808_RS19585	COG2860	membrane
D0808_RS19590	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
D0808_RS19595	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D0808_RS19600	COG2217	Heavy metal translocating P-type atpase
D0808_RS19605	COG2217	Heavy metal translocating P-type atpase
D0808_RS19610	COG2608	mercury ion transmembrane transporter activity
D0808_RS19615	COG1937	Protein conserved in bacteria
D0808_RS19620	COG0673	inositol 2-dehydrogenase activity
D0808_RS19625	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D0808_RS19630	COG1289	transmembrane transporter activity
D0808_RS19640	COG2076	Multidrug Resistance protein
D0808_RS19645	COG1309	transcriptional regulator
D0808_RS19650	COG1028	Short-chain dehydrogenase reductase Sdr
D0808_RS19660	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
D0808_RS19665	COG0557	exoribonuclease II activity
D0808_RS19670	COG1647	Serine aminopeptidase, S33
D0808_RS19675	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D0808_RS19680	COG0596	Alpha beta hydrolase
D0808_RS19685	COG1476	TRANSCRIPTIONal
D0808_RS19690	COG1396	sequence-specific DNA binding
D0808_RS19695	COG1396	sequence-specific DNA binding
D0808_RS19700	COG1733	regulation of RNA biosynthetic process
D0808_RS19705	COG0840	transmembrane signaling receptor activity
D0808_RS19710	COG1174	glycine betaine transport
D0808_RS19715	COG1732	Glycine betaine
D0808_RS19720	COG1174	glycine betaine transport
D0808_RS19725	COG1125	glycine betaine transport
D0808_RS19725	COG0517	IMP dehydrogenase activity
D0808_RS19730	COG1510	regulation of RNA biosynthetic process
D0808_RS19735	COG1174	glycine betaine transport
D0808_RS19740	COG1732	Glycine betaine
D0808_RS19745	COG1174	glycine betaine transport
D0808_RS19750	COG0517	IMP dehydrogenase activity
D0808_RS19750	COG1125	glycine betaine transport
D0808_RS19755	COG1510	regulation of RNA biosynthetic process
D0808_RS19760	COG2095	MarC family integral membrane protein
D0808_RS19770	COG3064	Membrane
D0808_RS19775	COG4640	response to antibiotic
D0808_RS19780	COG0456	acetyltransferase
D0808_RS19785	COG0148	phosphopyruvate hydratase activity
D0808_RS19790	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
D0808_RS19795	COG0149	triose-phosphate isomerase activity
D0808_RS19800	COG0126	phosphoglycerate kinase activity
D0808_RS19805	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D0808_RS19810	COG2390	Transcriptional regulator
D0808_RS19815	COG2814	Major facilitator Superfamily
D0808_RS19820	COG1609	Transcriptional regulator
D0808_RS19825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D0808_RS19830	COG0583	DNA-binding transcription factor activity
D0808_RS19835	COG0697	spore germination
D0808_RS19840	COG1113	amino acid transport
D0808_RS19845	COG3858	chitin binding
D0808_RS19850	COG1556	Lactate utilization protein
D0808_RS19855	COG1139	Iron-sulfur cluster binding protein
D0808_RS19860	COG0247	lactate metabolic process
D0808_RS19865	COG2197	response regulator
D0808_RS19870	COG4585	Histidine kinase
D0808_RS19875	COG0842	Transport permease protein
D0808_RS19880	COG1131	(ABC) transporter
D0808_RS19885	COG0596	Alpha beta hydrolase
D0808_RS19890	COG2208	phosphoserine phosphatase activity
D0808_RS19895	COG3867	Arabinogalactan endo-beta-1,4-galactanase
D0808_RS19900	COG1874	Beta-galactosidase
D0808_RS19905	COG3833	ABC-type maltose transport systems, permease component
D0808_RS19910	COG1175	transmembrane transport
D0808_RS19915	COG2182	Extracellular solute-binding protein
D0808_RS19920	COG1609	Transcriptional regulator
D0808_RS19925	COG2186	Transcriptional regulator
D0808_RS19930	COG1620	l-lactate permease
D0808_RS19935	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
D0808_RS19945	COG5039	Polysaccharide pyruvyl transferase
D0808_RS19950	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D0808_RS19955	COG0110	maltose O-acetyltransferase activity
D0808_RS19960	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D0808_RS19965	COG2244	polysaccharide biosynthetic process
D0808_RS19970	COG1216	Glycosyl transferase, family 2
D0808_RS19975	COG5039	Polysaccharide pyruvyl transferase
D0808_RS19980	COG1216	Glycosyl transferase, family 2
D0808_RS19990	COG0438	transferase activity, transferring glycosyl groups
D0808_RS19995	COG1215	transferase activity, transferring glycosyl groups
D0808_RS20000	COG0438	transferase activity, transferring glycosyl groups
D0808_RS20005	COG1086	Polysaccharide biosynthesis protein
D0808_RS20010	COG0489	protein tyrosine kinase activity
D0808_RS20015	COG3944	biosynthesis protein
D0808_RS20020	COG1396	sequence-specific DNA binding
D0808_RS20025	COG2272	Belongs to the type-B carboxylesterase lipase family
D0808_RS20035	COG3479	Phenolic acid decarboxylase
D0808_RS20045	COG1794	racemase activity, acting on amino acids and derivatives
D0808_RS20050	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D0808_RS20060	COG1621	beta-fructofuranosidase activity
D0808_RS20065	COG1621	beta-fructofuranosidase activity
D0808_RS20070	COG0531	amino acid
D0808_RS20075	COG1309	transcriptional regulator
D0808_RS20080	COG2076	Multidrug Resistance protein
D0808_RS20085	COG2076	Multidrug Resistance protein
D0808_RS20095	COG3621	Patatin-like phospholipase
D0808_RS20105	COG0740	serine-type endopeptidase activity
D0808_RS20110	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D0808_RS20115	COG0366	Alpha amylase catalytic
D0808_RS20120	COG1554	hydrolase, family 65, central catalytic
D0808_RS20125	COG5521	maltodextrose utilization protein MalA
D0808_RS20130	COG3833	ABC-type maltose transport systems, permease component
D0808_RS20135	COG1175	transmembrane transport
D0808_RS20140	COG2182	Extracellular solute-binding protein
D0808_RS20145	COG0366	Alpha amylase catalytic
D0808_RS20150	COG1609	Transcriptional regulator
D0808_RS20155	COG1611	Belongs to the LOG family
D0808_RS20160	COG1694	Mazg nucleotide pyrophosphohydrolase
D0808_RS20165	COG0659	secondary active sulfate transmembrane transporter activity
D0808_RS20170	COG0288	reversible hydration of carbon dioxide
D0808_RS20175	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D0808_RS20180	COG0577	efflux transmembrane transporter activity
D0808_RS20185	COG1136	(ABC) transporter
D0808_RS20190	COG5002	protein histidine kinase activity
D0808_RS20195	COG0745	RESPONSE REGULATOR receiver
D0808_RS20205	COG2162	N-hydroxyarylamine O-acetyltransferase activity
D0808_RS20210	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0808_RS20215	COG1481	regulation of sporulation
D0808_RS20220	COG0391	Required for morphogenesis under gluconeogenic growth conditions
D0808_RS20225	COG1660	Displays ATPase and GTPase activities
D0808_RS20230	COG1051	belongs to the nudix hydrolase family
D0808_RS20235	COG0492	ferredoxin-NADP+ reductase activity
D0808_RS20240	COG0791	NLP P60 protein
D0808_RS20240	COG3883	PFAM NLP P60 protein
D0808_RS20245	COG0457	Tetratricopeptide repeat
D0808_RS20250	COG1132	(ABC) transporter
D0808_RS20285	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
D0808_RS20285	COG0140	phosphoribosyl-ATP diphosphatase activity
D0808_RS20290	COG0107	imidazoleglycerol-phosphate synthase activity
D0808_RS20295	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
D0808_RS20300	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
D0808_RS20305	COG0131	Imidazoleglycerol-phosphate dehydratase
D0808_RS20310	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
D0808_RS20315	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
D0808_RS20320	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
D0808_RS20325	COG4990	cell redox homeostasis
D0808_RS20330	COG5297	Belongs to the glycosyl hydrolase family 6
D0808_RS20335	COG0110	maltose O-acetyltransferase activity
D0808_RS20340	COG0546	phosphoglycolate phosphatase activity
D0808_RS20345	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
D0808_RS20350	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
D0808_RS20355	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
D0808_RS20360	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
D0808_RS20365	COG0363	glucosamine-6-phosphate deaminase activity
D0808_RS20370	COG2188	Transcriptional regulator
D0808_RS20375	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D0808_RS20380	COG1950	PFAM Membrane protein of
D0808_RS20385	COG1983	PspC domain protein
D0808_RS20390	COG3595	metallopeptidase activity
D0808_RS20405	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D0808_RS20410	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D0808_RS20415	COG0556	nucleotide-excision repair
D0808_RS20420	COG4897	Protein conserved in bacteria
D0808_RS20425	COG0574	Belongs to the PEP-utilizing enzyme family
D0808_RS20425	COG3848	Pyruvate phosphate dikinase
D0808_RS20430	COG1309	transcriptional regulator
D0808_RS20435	COG2814	Major facilitator Superfamily
D0808_RS20440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D0808_RS20450	COG3409	Peptidoglycan-binding domain 1 protein
D0808_RS20450	COG0793	Belongs to the peptidase S41A family
D0808_RS20455	COG2177	Part of the ABC transporter FtsEX involved in
D0808_RS20460	COG2884	Cell division ATP-binding protein ftsE
D0808_RS20465	COG2010	Cytochrome c
D0808_RS20470	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D0808_RS20480	COG0653	protein targeting
D0808_RS20485	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
D0808_RS20500	COG1516	flagellar protein fliS
D0808_RS20505	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
D0808_RS20510	COG1334	flagellar protein FlaG
D0808_RS20515	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D0808_RS20520	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
D0808_RS20525	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
D0808_RS20535	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D0808_RS20540	COG4786	Flagellar basal body rod
D0808_RS20540	COG1256	bacterial-type flagellum assembly
D0808_RS20545	COG3418	PFAM FlgN family protein
D0808_RS20550	COG2747	anti-sigma28 factor FlgM
D0808_RS20560	COG1040	competence protein
D0808_RS20570	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
D0808_RS20575	COG1307	EDD domain protein, DegV family
D0808_RS20580	COG2197	response regulator
D0808_RS20585	COG4585	Histidine kinase
D0808_RS20590	COG1739	Uncharacterized protein family UPF0029
D0808_RS20595	COG1316	TRANSCRIPTIONal
D0808_RS20600	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D0808_RS20605	COG0438	transferase activity, transferring glycosyl groups
D0808_RS20610	COG1215	transferase activity, transferring glycosyl groups
D0808_RS20615	COG3206	protein involved in exopolysaccharide biosynthesis
D0808_RS20620	COG3307	-O-antigen
D0808_RS20625	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D0808_RS20630	COG0297	glycogen (starch) synthase activity
D0808_RS20630	COG0438	transferase activity, transferring glycosyl groups
D0808_RS20635	COG2244	polysaccharide biosynthetic process
D0808_RS20645	COG0860	N-Acetylmuramoyl-L-alanine amidase
D0808_RS20645	COG2247	cell wall binding repeat
D0808_RS20650	COG2385	sporulation resulting in formation of a cellular spore
D0808_RS20650	COG2247	cell wall binding repeat
D0808_RS20660	COG1316	TRANSCRIPTIONal
D0808_RS20665	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
D0808_RS20670	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D0808_RS20690	COG1215	transferase activity, transferring glycosyl groups
D0808_RS20690	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D0808_RS20695	COG0463	Glycosyl transferase, family 2
D0808_RS20710	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D0808_RS20715	COG1134	teichoic acid transport
D0808_RS20720	COG1682	transport, permease protein
D0808_RS20725	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D0808_RS20730	COG0438	transferase activity, transferring glycosyl groups
D0808_RS20735	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
D0808_RS20740	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
D0808_RS20745	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D0808_RS20755	COG4193	domain, Protein
D0808_RS20760	COG1482	cell wall glycoprotein biosynthetic process
D0808_RS20765	COG0697	spore germination
D0808_RS20770	COG0814	amino acid
D0808_RS20780	COG2814	Major facilitator Superfamily
D0808_RS20785	COG1316	TRANSCRIPTIONal
D0808_RS20790	COG0561	phosphatase activity
D0808_RS20795	COG0791	NLP P60 protein
D0808_RS20805	COG2843	Capsule synthesis protein
D0808_RS20815	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
D0808_RS20820	COG1609	Transcriptional regulator
D0808_RS20825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D0808_RS20830	COG1869	D-ribose catabolic process
D0808_RS20835	COG1129	ABC transporter
D0808_RS20840	COG1172	Belongs to the binding-protein-dependent transport system permease family
D0808_RS20845	COG1879	ABC-type sugar transport system periplasmic component
D0808_RS20850	COG3103	Sh3 type 3 domain protein
D0808_RS20860	COG2249	NAD(P)H dehydrogenase (quinone) activity
D0808_RS20865	COG3527	Alpha-acetolactate decarboxylase
D0808_RS20870	COG0028	Belongs to the TPP enzyme family
D0808_RS20875	COG0583	DNA-binding transcription factor activity
D0808_RS20880	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D0808_RS20895	COG5337	Spore coat protein CotH
