locus-tag	class	description
IRJ26_RS00010	COG0768	penicillin binding
IRJ26_RS00015	COG2340	Cysteine-rich secretory protein family
IRJ26_RS00020	COG2084	Dehydrogenase
IRJ26_RS00025	COG0840	transmembrane signaling receptor activity
IRJ26_RS00030	COG0456	acetyltransferase
IRJ26_RS00035	COG1533	DNA photolyase activity
IRJ26_RS00045	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IRJ26_RS00050	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IRJ26_RS00055	COG1263	PTS System
IRJ26_RS00055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IRJ26_RS00055	COG2190	(PTS) system
IRJ26_RS00060	COG3711	transcriptional antiterminator
IRJ26_RS00065	COG1609	Transcriptional regulator
IRJ26_RS00070	COG0006	proline dipeptidase activity
IRJ26_RS00080	COG2217	Heavy metal translocating P-type atpase
IRJ26_RS00085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IRJ26_RS00090	COG2244	polysaccharide biosynthetic process
IRJ26_RS00095	COG3773	Cell wall hydrolase
IRJ26_RS00105	COG4873	Protein conserved in bacteria
IRJ26_RS00115	COG3858	chitin binding
IRJ26_RS00120	COG3858	chitin binding
IRJ26_RS00125	COG1388	LysM domain
IRJ26_RS00130	COG1388	LysM domain
IRJ26_RS00130	COG4641	Protein conserved in bacteria
IRJ26_RS00135	COG1028	Short-chain dehydrogenase reductase Sdr
IRJ26_RS00140	COG1733	regulation of RNA biosynthetic process
IRJ26_RS00145	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IRJ26_RS00150	COG0602	queuosine metabolic process
IRJ26_RS00155	COG0720	synthase
IRJ26_RS00160	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IRJ26_RS00165	COG3949	Membrane
IRJ26_RS00170	COG0542	response to heat
IRJ26_RS00175	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IRJ26_RS00180	COG1360	Flagellar Motor Protein
IRJ26_RS00185	COG1846	Transcriptional regulator
IRJ26_RS00190	COG3852	Histidine kinase
IRJ26_RS00205	COG3339	Conserved Protein
IRJ26_RS00210	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
IRJ26_RS00215	COG0235	Class ii aldolase
IRJ26_RS00220	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
IRJ26_RS00225	COG1850	ribulose-bisphosphate carboxylase activity
IRJ26_RS00230	COG0436	Aminotransferase
IRJ26_RS00235	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IRJ26_RS00240	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
IRJ26_RS00245	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IRJ26_RS00255	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IRJ26_RS00260	COG5002	protein histidine kinase activity
IRJ26_RS00265	COG3594	Acyltransferase
IRJ26_RS00280	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IRJ26_RS00285	COG0501	Belongs to the peptidase M48B family
IRJ26_RS00305	COG1191	sigma factor activity
IRJ26_RS00310	COG0861	Integral membrane protein TerC family
IRJ26_RS00315	COG0586	Pfam SNARE associated Golgi protein
IRJ26_RS00320	COG3300	MHYT domain
IRJ26_RS00320	COG5001	Diguanylate cyclase
IRJ26_RS00325	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
IRJ26_RS00330	COG1793	dna ligase
IRJ26_RS00330	COG3285	dna ligase
IRJ26_RS00335	COG0463	Glycosyl transferase, family 2
IRJ26_RS00345	COG1408	metallophosphoesterase
IRJ26_RS00350	COG0726	polysaccharide deacetylase
IRJ26_RS00355	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IRJ26_RS00360	COG1846	Transcriptional regulator
IRJ26_RS00375	COG0789	Transcriptional regulator
IRJ26_RS00380	COG2239	Acts as a magnesium transporter
IRJ26_RS00390	COG3212	peptidase
IRJ26_RS00395	COG3212	peptidase
IRJ26_RS00400	COG3850	Histidine kinase
IRJ26_RS00400	COG5002	protein histidine kinase activity
IRJ26_RS00405	COG0745	RESPONSE REGULATOR receiver
IRJ26_RS00415	COG4721	ABC-type cobalt transport system, permease component
IRJ26_RS00420	COG1122	ATPase activity
IRJ26_RS00425	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IRJ26_RS00430	COG1366	Belongs to the anti-sigma-factor antagonist family
IRJ26_RS00435	COG1404	Belongs to the peptidase S8 family
IRJ26_RS00440	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IRJ26_RS00445	COG0590	tRNA wobble adenosine to inosine editing
IRJ26_RS00455	COG1764	response to oxidative stress
IRJ26_RS00460	COG1846	Transcriptional regulator
IRJ26_RS00465	COG1764	response to oxidative stress
IRJ26_RS00470	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IRJ26_RS00475	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IRJ26_RS00480	COG0788	formyltetrahydrofolate deformylase activity
IRJ26_RS00485	COG2076	Multidrug Resistance protein
IRJ26_RS00490	COG2076	Multidrug Resistance protein
IRJ26_RS00495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IRJ26_RS00500	COG2318	DinB family
IRJ26_RS00505	COG2323	membrane
IRJ26_RS00515	COG1017	nitric oxide dioxygenase activity
IRJ26_RS00515	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IRJ26_RS00520	COG1607	acyl-coa hydrolase
IRJ26_RS00525	COG1834	amidinotransferase
IRJ26_RS00530	COG2706	6-phosphogluconolactonase activity
IRJ26_RS00535	COG4608	Belongs to the ABC transporter superfamily
IRJ26_RS00540	COG0791	NLP P60 protein
IRJ26_RS00545	COG4948	Mandelate Racemase Muconate Lactonizing
IRJ26_RS00550	COG1619	proteins homologs of microcin C7 resistance protein MccF
IRJ26_RS00555	COG4166	transmembrane transport
IRJ26_RS00560	COG0444	Belongs to the ABC transporter superfamily
IRJ26_RS00565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IRJ26_RS00570	COG0601	transmembrane transport
IRJ26_RS00575	COG2362	D-Aminopeptidase
IRJ26_RS00580	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IRJ26_RS00585	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IRJ26_RS00595	COG0463	Glycosyl transferase, family 2
IRJ26_RS00600	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IRJ26_RS00610	COG0346	lactoylglutathione lyase activity
IRJ26_RS00615	COG0531	amino acid
IRJ26_RS00620	COG1392	Phosphate transport regulator
IRJ26_RS00625	COG0306	phosphate transporter
IRJ26_RS00645	COG3409	Peptidoglycan-binding domain 1 protein
IRJ26_RS00645	COG5632	N-Acetylmuramoyl-L-alanine amidase
IRJ26_RS00685	COG3778	Protein conserved in bacteria
IRJ26_RS00690	COG3299	homolog of phage Mu protein gp47
IRJ26_RS00695	COG3628	GPW Gp25 family protein
IRJ26_RS00705	COG4193	domain, Protein
IRJ26_RS00710	COG1652	LysM domain
IRJ26_RS00715	COG5412	phage tail tape measure protein
IRJ26_RS00715	COG3953	SLT domain
IRJ26_RS00765	COG4653	Phage capsid family
IRJ26_RS00770	COG0338	D12 class N6 adenine-specific DNA methyltransferase
IRJ26_RS00775	COG5518	Phage portal protein
IRJ26_RS00780	COG1783	phage Terminase large subunit
IRJ26_RS00785	COG3728	DNA packaging
IRJ26_RS00785	COG5484	DNA packaging
IRJ26_RS00790	COG1595	DNA-templated transcription, initiation
IRJ26_RS00810	COG1484	DNA-dependent DNA replication
IRJ26_RS00815	COG1522	sequence-specific DNA binding
IRJ26_RS00825	COG1396	sequence-specific DNA binding
IRJ26_RS00830	COG2856	Zn peptidase
IRJ26_RS00835	COG3546	catalase activity
IRJ26_RS00840	COG4195	phage-related replication protein
IRJ26_RS00850	COG1388	LysM domain
IRJ26_RS00850	COG3409	Peptidoglycan-binding domain 1 protein
IRJ26_RS00850	COG5632	N-Acetylmuramoyl-L-alanine amidase
IRJ26_RS00855	COG2350	Protein conserved in bacteria
IRJ26_RS00865	COG0457	Tetratricopeptide repeat
IRJ26_RS00870	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IRJ26_RS00875	COG2318	DinB family
IRJ26_RS00880	COG0730	response to heat
IRJ26_RS00885	COG2721	sulfolactate sulfo-lyase activity
IRJ26_RS00890	COG0246	Mannitol dehydrogenase
IRJ26_RS00895	COG1609	Transcriptional regulator
IRJ26_RS00900	COG2271	Major facilitator Superfamily
IRJ26_RS00905	COG1028	Short-chain dehydrogenase reductase Sdr
IRJ26_RS00910	COG1312	Catalyzes the dehydration of D-mannonate
IRJ26_RS00915	COG1063	alcohol dehydrogenase
IRJ26_RS00920	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
IRJ26_RS00925	COG2211	Major facilitator Superfamily
IRJ26_RS00930	COG1904	glucuronate isomerase
IRJ26_RS00935	COG1252	NADH dehydrogenase
IRJ26_RS00945	COG4297	protein containing double-stranded beta helix domain
IRJ26_RS00950	COG0697	spore germination
IRJ26_RS00955	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IRJ26_RS00960	COG0390	transport system, permease component
IRJ26_RS00965	COG1587	Uroporphyrinogen-III synthase
IRJ26_RS00975	COG1819	glycosyl
IRJ26_RS00980	COG2124	cytochrome p450
IRJ26_RS00990	COG1051	belongs to the nudix hydrolase family
IRJ26_RS01000	COG2427	Protein of unknown function (DUF1641)
IRJ26_RS01005	COG3383	formate dehydrogenase (NAD+) activity
IRJ26_RS01015	COG2205	protein histidine kinase activity
IRJ26_RS01020	COG5504	Zn-dependent protease
IRJ26_RS01035	COG0726	polysaccharide deacetylase
IRJ26_RS01045	COG0109	protoheme IX farnesyltransferase activity
IRJ26_RS01060	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IRJ26_RS01070	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IRJ26_RS01080	COG1482	cell wall glycoprotein biosynthetic process
IRJ26_RS01085	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IRJ26_RS01085	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IRJ26_RS01085	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IRJ26_RS01090	COG3711	transcriptional antiterminator
IRJ26_RS01090	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IRJ26_RS01100	COG1028	Short-chain dehydrogenase reductase Sdr
IRJ26_RS01105	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IRJ26_RS01110	COG5484	DNA packaging
IRJ26_RS01125	COG3677	Transposase
IRJ26_RS01160	COG5505	Protein of unknown function (DUF819)
IRJ26_RS01165	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IRJ26_RS01170	COG0626	cystathionine gamma-synthase activity
IRJ26_RS01175	COG0626	cystathionine gamma-synthase activity
IRJ26_RS01180	COG2382	esterase
IRJ26_RS01185	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IRJ26_RS01190	COG2153	protein acetylation
IRJ26_RS01200	COG0210	DNA helicase
IRJ26_RS01255	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IRJ26_RS01260	COG0351	phosphomethylpyrimidine kinase
IRJ26_RS01265	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IRJ26_RS01270	COG2022	thiamine diphosphate biosynthetic process
IRJ26_RS01275	COG2104	thiamine diphosphate biosynthetic process
IRJ26_RS01280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IRJ26_RS01285	COG0352	thiamine-phosphate diphosphorylase activity
IRJ26_RS01290	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IRJ26_RS01295	COG0475	glutathione-regulated potassium exporter activity
IRJ26_RS01295	COG0569	domain protein
IRJ26_RS01300	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IRJ26_RS01305	COG0564	pseudouridine synthase activity
IRJ26_RS01310	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IRJ26_RS01315	COG2357	RelA SpoT domain protein
IRJ26_RS01325	COG4116	CYTH
IRJ26_RS01330	COG0741	lytic transglycosylase activity
IRJ26_RS01335	COG2346	COG2346, Truncated hemoglobins
IRJ26_RS01340	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IRJ26_RS01350	COG1164	Oligoendopeptidase f
IRJ26_RS01355	COG4469	Competence protein
IRJ26_RS01365	COG4862	establishment of competence for transformation
IRJ26_RS01375	COG0861	Integral membrane protein TerC family
IRJ26_RS01380	COG1393	Belongs to the ArsC family
IRJ26_RS01385	COG0456	acetyltransferase
IRJ26_RS01390	COG2814	Major facilitator Superfamily
IRJ26_RS01395	COG4608	Belongs to the ABC transporter superfamily
IRJ26_RS01400	COG0444	Belongs to the ABC transporter superfamily
IRJ26_RS01405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IRJ26_RS01410	COG0601	transmembrane transport
IRJ26_RS01415	COG4166	transmembrane transport
IRJ26_RS01420	COG0180	Tryptophanyl-tRNA synthetase
IRJ26_RS01430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IRJ26_RS01435	COG0601	transmembrane transport
IRJ26_RS01445	COG4608	Belongs to the ABC transporter superfamily
IRJ26_RS01450	COG0444	Belongs to the ABC transporter superfamily
IRJ26_RS01455	COG5504	Zn-dependent protease
IRJ26_RS01460	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IRJ26_RS01465	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IRJ26_RS01480	COG1744	ABC transporter substrate-binding protein PnrA-like
IRJ26_RS01490	COG2267	carboxylic ester hydrolase activity
IRJ26_RS01505	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IRJ26_RS01510	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IRJ26_RS01515	COG0505	Belongs to the CarA family
IRJ26_RS01520	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IRJ26_RS01530	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IRJ26_RS01535	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IRJ26_RS01540	COG2271	Major facilitator Superfamily
IRJ26_RS01545	COG0277	FAD linked oxidase domain protein
IRJ26_RS01555	COG2151	metal-sulfur cluster biosynthetic enzyme
IRJ26_RS01560	COG1073	alpha beta
IRJ26_RS01565	COG0561	phosphatase activity
IRJ26_RS01585	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IRJ26_RS01590	COG1307	EDD domain protein, DegV family
IRJ26_RS01595	COG3227	Zinc metalloprotease (Elastase)
IRJ26_RS01610	COG1695	Transcriptional regulator
IRJ26_RS01630	COG2996	Protein conserved in bacteria
IRJ26_RS01635	COG1666	GTP binding
IRJ26_RS01640	COG0646	methionine synthase
IRJ26_RS01640	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IRJ26_RS01645	COG2153	protein acetylation
IRJ26_RS01650	COG0454	-acetyltransferase
IRJ26_RS01655	COG2814	Major facilitator Superfamily
IRJ26_RS01660	COG4948	Mandelate Racemase Muconate Lactonizing
IRJ26_RS01665	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IRJ26_RS01670	COG1809	phosphosulfolactate synthase activity
IRJ26_RS01675	COG2045	Belongs to the ComB family
IRJ26_RS01680	COG0175	sulfate reduction
IRJ26_RS01685	COG2046	Belongs to the sulfate adenylyltransferase family
IRJ26_RS01690	COG0529	Catalyzes the synthesis of activated sulfate
IRJ26_RS01695	COG2267	carboxylic ester hydrolase activity
IRJ26_RS01700	COG1357	PFAM Pentapeptide repeats (8 copies)
IRJ26_RS01705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IRJ26_RS01710	COG1279	arginine transmembrane transporter activity
IRJ26_RS01715	COG2318	DinB family
IRJ26_RS01720	COG0673	inositol 2-dehydrogenase activity
IRJ26_RS01725	COG1609	Transcriptional regulator
IRJ26_RS01730	COG1917	Cupin 2, conserved barrel domain protein
IRJ26_RS01730	COG2207	Transcriptional regulator
IRJ26_RS01735	COG0534	Mate efflux family protein
IRJ26_RS01740	COG1562	ergosterol biosynthetic process
IRJ26_RS01745	COG2318	DinB family
IRJ26_RS01750	COG0367	asparagine synthase
IRJ26_RS01760	COG1404	Belongs to the peptidase S8 family
IRJ26_RS01770	COG0179	Fumarylacetoacetate (FAA) hydrolase
IRJ26_RS01775	COG5337	Spore coat protein CotH
IRJ26_RS01815	COG1403	HNH endonuclease
IRJ26_RS01820	COG0419	ATPase involved in DNA repair
IRJ26_RS01825	COG0420	3'-5' exonuclease activity
IRJ26_RS01830	COG1074	ATP-dependent DNA helicase activity
IRJ26_RS01835	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
IRJ26_RS01840	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
IRJ26_RS01850	COG4533	DNA binding
IRJ26_RS01855	COG2814	Major facilitator Superfamily
IRJ26_RS01855	COG0477	Major facilitator Superfamily
IRJ26_RS01860	COG3180	Ammonia monooxygenase
IRJ26_RS01865	COG1609	Transcriptional regulator
IRJ26_RS01870	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IRJ26_RS01875	COG0561	phosphatase activity
IRJ26_RS01880	COG0673	inositol 2-dehydrogenase activity
IRJ26_RS01885	COG0738	Major facilitator superfamily
IRJ26_RS01890	COG1846	Transcriptional regulator
IRJ26_RS01895	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IRJ26_RS01900	COG0681	Belongs to the peptidase S26 family
IRJ26_RS01905	COG0398	Pfam SNARE associated Golgi protein
IRJ26_RS01920	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IRJ26_RS01930	COG1028	Short-chain dehydrogenase reductase Sdr
IRJ26_RS01935	COG4903	ComK protein
IRJ26_RS01945	COG1028	Short-chain dehydrogenase reductase Sdr
IRJ26_RS01950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IRJ26_RS01950	COG0723	plastoquinol--plastocyanin reductase activity
IRJ26_RS01955	COG0840	transmembrane signaling receptor activity
IRJ26_RS01960	COG1268	BioY protein
IRJ26_RS01965	COG0318	PFAM AMP-dependent synthetase and ligase
IRJ26_RS01970	COG0183	Belongs to the thiolase family
IRJ26_RS01975	COG0406	alpha-ribazole phosphatase activity
IRJ26_RS01980	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
IRJ26_RS01985	COG0604	alcohol dehydrogenase
IRJ26_RS01990	COG0456	acetyltransferase
IRJ26_RS01995	COG1404	Belongs to the peptidase S8 family
IRJ26_RS02000	COG0501	Belongs to the peptidase M48B family
IRJ26_RS02010	COG0318	PFAM AMP-dependent synthetase and ligase
IRJ26_RS02015	COG0702	epimerase
IRJ26_RS02020	COG0095	Lipoate-protein ligase
IRJ26_RS02025	COG1234	tRNA 3'-trailer cleavage
IRJ26_RS02035	COG1301	dicarboxylic acid transport
IRJ26_RS02040	COG4405	Protein conserved in bacteria
IRJ26_RS02045	COG1363	Peptidase, m42
IRJ26_RS02055	COG4377	Putative membrane peptidase family (DUF2324)
IRJ26_RS02060	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IRJ26_RS02065	COG1511	domain protein
IRJ26_RS02070	COG1309	transcriptional regulator
IRJ26_RS02075	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IRJ26_RS02080	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
IRJ26_RS02085	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IRJ26_RS02090	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IRJ26_RS02095	COG2329	Antibiotic biosynthesis monooxygenase
IRJ26_RS02105	COG3069	C4-dicarboxylate transmembrane transporter activity
IRJ26_RS02110	COG1473	amidohydrolase
IRJ26_RS02120	COG4473	ABC transporter
IRJ26_RS02125	COG1131	(ABC) transporter
IRJ26_RS02130	COG0537	adenosine 5'-monophosphoramidase activity
IRJ26_RS02135	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IRJ26_RS02150	COG4980	gas vesicle protein
IRJ26_RS02155	COG1846	Transcriptional regulator
IRJ26_RS02185	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IRJ26_RS02195	COG3481	metal-dependent phosphohydrolase, HD sub domain
IRJ26_RS02200	COG4717	serine-type aminopeptidase activity
IRJ26_RS02205	COG0420	3'-5' exonuclease activity
IRJ26_RS02210	COG1668	transmembrane transport
IRJ26_RS02215	COG4152	abc transporter atp-binding protein
IRJ26_RS02225	COG1024	Enoyl-CoA hydratase
IRJ26_RS02235	COG0490	domain, Protein
IRJ26_RS02240	COG0475	glutathione-regulated potassium exporter activity
IRJ26_RS02245	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IRJ26_RS02250	COG0561	phosphatase activity
IRJ26_RS02255	COG4335	DNA alkylation repair
IRJ26_RS02260	COG3679	Belongs to the UPF0342 family
IRJ26_RS02265	COG4399	Belongs to the UPF0754 family
IRJ26_RS02270	COG0189	ligase activity
IRJ26_RS02275	COG0189	ligase activity
IRJ26_RS02295	COG0702	epimerase
IRJ26_RS02300	COG1132	(ABC) transporter
IRJ26_RS02305	COG1132	(ABC) transporter
IRJ26_RS02315	COG0589	response to stress
IRJ26_RS02320	COG1757	Na H antiporter
IRJ26_RS02325	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IRJ26_RS02330	COG0726	polysaccharide deacetylase
IRJ26_RS02335	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IRJ26_RS02340	COG0668	transmembrane transport
IRJ26_RS02350	COG0584	glycerophosphoryl diester phosphodiesterase
IRJ26_RS02355	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IRJ26_RS02360	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IRJ26_RS02365	COG1253	flavin adenine dinucleotide binding
IRJ26_RS02370	COG0436	Aminotransferase
IRJ26_RS02375	COG0789	Transcriptional regulator
IRJ26_RS02380	COG1253	flavin adenine dinucleotide binding
IRJ26_RS02385	COG0204	Acyl-transferase
IRJ26_RS02390	COG0667	Aldo Keto reductase
IRJ26_RS02395	COG1595	DNA-templated transcription, initiation
IRJ26_RS02410	COG0456	acetyltransferase
IRJ26_RS02415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IRJ26_RS02420	COG0733	neurotransmitter:sodium symporter activity
IRJ26_RS02425	COG0531	amino acid
IRJ26_RS02430	COG1028	Short-chain dehydrogenase reductase Sdr
IRJ26_RS02435	COG0372	Belongs to the citrate synthase family
IRJ26_RS02440	COG0583	DNA-binding transcription factor activity
IRJ26_RS02445	COG0791	NLP P60 protein
IRJ26_RS02445	COG1388	LysM domain
IRJ26_RS02450	COG1785	Belongs to the alkaline phosphatase family
IRJ26_RS02455	COG2719	SpoVR family
IRJ26_RS02460	COG0668	transmembrane transport
IRJ26_RS02465	COG1959	2 iron, 2 sulfur cluster binding
IRJ26_RS02470	COG0791	NLP P60 protein
IRJ26_RS02470	COG1388	LysM domain
IRJ26_RS02485	COG0431	NADPH-dependent FMN reductase
IRJ26_RS02490	COG2197	response regulator
IRJ26_RS02495	COG2203	Gaf domain
IRJ26_RS02495	COG4585	Histidine kinase
IRJ26_RS02500	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IRJ26_RS02505	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IRJ26_RS02510	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IRJ26_RS02515	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IRJ26_RS02520	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
IRJ26_RS02525	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IRJ26_RS02530	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IRJ26_RS02530	COG3153	acetyltransferase
IRJ26_RS02535	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IRJ26_RS02540	COG0517	IMP dehydrogenase activity
IRJ26_RS02550	COG0564	pseudouridine synthase activity
IRJ26_RS02555	COG3764	Sortase (surface protein transpeptidase)
IRJ26_RS02560	COG1525	nuclease
IRJ26_RS02560	COG4085	toxin activity
IRJ26_RS02560	COG0737	Belongs to the 5'-nucleotidase family
IRJ26_RS02565	COG5577	PFAM Coat F domain
IRJ26_RS02585	COG1823	symporter activity
IRJ26_RS02590	COG3706	GGDEF domain
IRJ26_RS02595	COG1464	Belongs to the NlpA lipoprotein family
IRJ26_RS02600	COG1278	Cold shock
IRJ26_RS02605	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
IRJ26_RS02610	COG1131	(ABC) transporter
IRJ26_RS02615	COG1131	(ABC) transporter
IRJ26_RS02620	COG1725	Transcriptional regulator
IRJ26_RS02640	COG0655	NAD(P)H dehydrogenase (quinone) activity
IRJ26_RS02645	COG2814	Major facilitator Superfamily
IRJ26_RS02650	COG1566	PFAM secretion protein HlyD family protein
IRJ26_RS02655	COG1846	Transcriptional regulator
IRJ26_RS02660	COG2718	Belongs to the UPF0229 family
IRJ26_RS02665	COG2766	serine protein kinase
IRJ26_RS02670	COG1664	Polymer-forming cytoskeletal
IRJ26_RS02675	COG1664	Polymer-forming cytoskeletal
IRJ26_RS02680	COG0789	Transcriptional regulator
IRJ26_RS02685	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IRJ26_RS02695	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IRJ26_RS02700	COG3382	B3 4 domain protein
IRJ26_RS02710	COG1476	TRANSCRIPTIONal
IRJ26_RS02720	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IRJ26_RS02730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IRJ26_RS02735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IRJ26_RS02740	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IRJ26_RS02745	COG1116	anion transmembrane transporter activity
IRJ26_RS02750	COG0753	catalase activity
IRJ26_RS02760	COG0277	FAD linked oxidase domain protein
IRJ26_RS02765	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IRJ26_RS02770	COG3340	Belongs to the peptidase S51 family
IRJ26_RS02775	COG5577	PFAM Coat F domain
IRJ26_RS02785	COG4326	sporulation control protein
IRJ26_RS02895	COG0735	belongs to the Fur family
IRJ26_RS02900	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IRJ26_RS02905	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IRJ26_RS02910	COG4129	membrane
IRJ26_RS02915	COG1132	(ABC) transporter
IRJ26_RS02920	COG3557	Belongs to the UPF0374 family
IRJ26_RS02935	COG1028	Short-chain dehydrogenase reductase Sdr
IRJ26_RS02945	COG1194	a g-specific adenine glycosylase
IRJ26_RS02950	COG1988	membrane-bound metal-dependent
IRJ26_RS02955	COG4485	Bacterial membrane protein, YfhO
IRJ26_RS02960	COG0463	Glycosyl transferase, family 2
IRJ26_RS02965	COG0596	Alpha beta hydrolase
IRJ26_RS02970	COG5658	integral membrane protein
IRJ26_RS02975	COG3103	Sh3 type 3 domain protein
IRJ26_RS02990	COG2814	Major facilitator Superfamily
IRJ26_RS03000	COG2137	regulation of response to DNA damage stimulus
IRJ26_RS03005	COG1090	epimerase
IRJ26_RS03020	COG0778	Nitroreductase
IRJ26_RS03025	COG0384	phenazine biosynthesis protein PhzF
IRJ26_RS03030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IRJ26_RS03035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IRJ26_RS03040	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IRJ26_RS03045	COG0392	lysyltransferase activity
IRJ26_RS03045	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IRJ26_RS03050	COG1846	Transcriptional regulator
IRJ26_RS03055	COG2814	Major facilitator Superfamily
IRJ26_RS03060	COG2318	DinB family
IRJ26_RS03065	COG2814	Major facilitator Superfamily
IRJ26_RS03070	COG1309	transcriptional regulator
IRJ26_RS03075	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
IRJ26_RS03080	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
IRJ26_RS03085	COG1695	Transcriptional regulator
IRJ26_RS03090	COG0842	Transport permease protein
IRJ26_RS03095	COG0842	Transport permease protein
IRJ26_RS03095	COG1511	domain protein
IRJ26_RS03100	COG1131	(ABC) transporter
IRJ26_RS03105	COG2197	response regulator
IRJ26_RS03110	COG4585	Histidine kinase
IRJ26_RS03115	COG0673	inositol 2-dehydrogenase activity
IRJ26_RS03120	COG1082	Xylose isomerase domain protein TIM barrel
IRJ26_RS03125	COG2814	Major facilitator Superfamily
IRJ26_RS03130	COG1917	Cupin 2, conserved barrel domain protein
IRJ26_RS03130	COG4977	sequence-specific DNA binding
IRJ26_RS03135	COG2514	catechol 2,3-dioxygenase activity
IRJ26_RS03140	COG2259	Doxx family
IRJ26_RS03145	COG1132	(ABC) transporter
IRJ26_RS03150	COG1132	(ABC) transporter
IRJ26_RS03155	COG1263	PTS System
IRJ26_RS03155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IRJ26_RS03160	COG1737	Transcriptional regulator
IRJ26_RS03165	COG1486	melibiose metabolic process
IRJ26_RS03170	COG4842	Belongs to the WXG100 family
IRJ26_RS03195	COG1742	UPF0060 membrane protein
IRJ26_RS03205	COG3284	Transcriptional regulator
IRJ26_RS03210	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IRJ26_RS03215	COG0508	dehydrogenase complex catalyzes the overall conversion of
IRJ26_RS03220	COG0022	dehydrogenase e1 component
IRJ26_RS03225	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IRJ26_RS03235	COG4637	Psort location Cytoplasmic, score
IRJ26_RS03240	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IRJ26_RS03250	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IRJ26_RS03255	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IRJ26_RS03260	COG0598	Magnesium transport protein CorA
IRJ26_RS03265	COG2084	Dehydrogenase
IRJ26_RS03270	COG0726	polysaccharide deacetylase
IRJ26_RS03280	COG0535	radical SAM domain protein
IRJ26_RS03285	COG0668	transmembrane transport
IRJ26_RS03295	COG0387	Pfam Sodium calcium exchanger
IRJ26_RS03300	COG0477	Major facilitator Superfamily
IRJ26_RS03305	COG1295	ribonuclease BN
IRJ26_RS03310	COG4980	gas vesicle protein
IRJ26_RS03315	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IRJ26_RS03320	COG4840	Belongs to the UPF0435 family
IRJ26_RS03325	COG2814	Major facilitator Superfamily
IRJ26_RS03330	COG0693	protein deglycase activity
IRJ26_RS03335	COG0737	Belongs to the 5'-nucleotidase family
IRJ26_RS03340	COG0778	Nitroreductase
IRJ26_RS03345	COG2188	Transcriptional regulator
IRJ26_RS03350	COG0366	Alpha amylase catalytic
IRJ26_RS03355	COG1263	PTS System
IRJ26_RS03355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IRJ26_RS03360	COG0697	spore germination
IRJ26_RS03375	COG0531	amino acid
IRJ26_RS03380	COG1115	amino acid carrier protein
IRJ26_RS03395	COG1368	sulfuric ester hydrolase activity
IRJ26_RS03400	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IRJ26_RS03400	COG1263	PTS System
IRJ26_RS03405	COG0024	Methionine aminopeptidase
IRJ26_RS03425	COG2258	MOSC domain
IRJ26_RS03430	COG1254	Belongs to the acylphosphatase family
IRJ26_RS03435	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
IRJ26_RS03440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IRJ26_RS03445	COG2851	Citrate transporter
IRJ26_RS03450	COG3181	Tripartite tricarboxylate transporter family receptor
IRJ26_RS03455	COG4565	transcriptional regulatory protein
IRJ26_RS03460	COG3290	protein histidine kinase activity
IRJ26_RS03465	COG0471	metal ion transport
IRJ26_RS03470	COG3866	Pectate lyase
IRJ26_RS03485	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
IRJ26_RS03490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IRJ26_RS03495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IRJ26_RS03500	COG1120	ATPase activity
IRJ26_RS03505	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IRJ26_RS03510	COG2211	Major facilitator Superfamily
IRJ26_RS03515	COG2130	NADP-dependent
IRJ26_RS03520	COG0456	acetyltransferase
IRJ26_RS03525	COG0513	Belongs to the DEAD box helicase family
IRJ26_RS03530	COG0488	(ABC) transporter
IRJ26_RS03540	COG2814	Major facilitator Superfamily
IRJ26_RS03545	COG0789	Transcriptional regulator
IRJ26_RS03555	COG0488	(ABC) transporter
IRJ26_RS03560	COG0840	transmembrane signaling receptor activity
IRJ26_RS03565	COG1012	belongs to the aldehyde dehydrogenase family
IRJ26_RS03570	COG0531	amino acid
IRJ26_RS03575	COG1011	Hydrolase
IRJ26_RS03580	COG2223	nitrite transmembrane transporter activity
IRJ26_RS03585	COG1442	glycosyl transferase family 8
IRJ26_RS03590	COG1216	Glycosyl transferase, family 2
IRJ26_RS03595	COG1442	glycosyl transferase family 8
IRJ26_RS03600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IRJ26_RS03605	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IRJ26_RS03610	COG1368	sulfuric ester hydrolase activity
IRJ26_RS03615	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IRJ26_RS03615	COG2124	cytochrome p450
IRJ26_RS03625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IRJ26_RS03630	COG1846	Transcriptional regulator
IRJ26_RS03635	COG0697	spore germination
IRJ26_RS03640	COG0670	Belongs to the BI1 family
IRJ26_RS03645	COG5583	Uncharacterized small protein (DUF2292)
IRJ26_RS03660	COG0346	lactoylglutathione lyase activity
IRJ26_RS03665	COG2329	Antibiotic biosynthesis monooxygenase
IRJ26_RS03670	COG2323	membrane
IRJ26_RS03675	COG1486	melibiose metabolic process
IRJ26_RS03680	COG0395	ABC-type sugar transport system, permease component
IRJ26_RS03685	COG4209	transmembrane transport
IRJ26_RS03690	COG1653	transport
IRJ26_RS03700	COG1874	Beta-galactosidase
IRJ26_RS03705	COG2755	lipolytic protein G-D-S-L family
IRJ26_RS03710	COG3401	FG-GAP repeat protein
IRJ26_RS03715	COG3401	FG-GAP repeat protein
IRJ26_RS03720	COG5578	integral membrane protein
IRJ26_RS03730	COG2755	lipolytic protein G-D-S-L family
IRJ26_RS03735	COG2207	Transcriptional regulator
IRJ26_RS03740	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
IRJ26_RS03745	COG0395	ABC-type sugar transport system, permease component
IRJ26_RS03750	COG1175	transmembrane transport
IRJ26_RS03755	COG1653	transport
IRJ26_RS03760	COG2207	Transcriptional regulator
IRJ26_RS03760	COG4753	response regulator
IRJ26_RS03765	COG2972	Histidine kinase
IRJ26_RS03770	COG5578	integral membrane protein
IRJ26_RS03780	COG0454	-acetyltransferase
IRJ26_RS03785	COG3546	catalase activity
IRJ26_RS03800	COG0702	epimerase
IRJ26_RS03805	COG3631	Ketosteroid isomerase-related protein
IRJ26_RS03810	COG1309	transcriptional regulator
IRJ26_RS03820	COG0217	transcriptional regulatory protein
IRJ26_RS03830	COG0457	Tetratricopeptide repeat
IRJ26_RS03835	COG3391	amine dehydrogenase activity
IRJ26_RS03840	COG5444	nuclease activity
IRJ26_RS03860	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IRJ26_RS03865	COG1061	Type III restriction enzyme res subunit
IRJ26_RS03870	COG1002	Type II restriction enzyme, methylase subunits
IRJ26_RS03875	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IRJ26_RS03880	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IRJ26_RS03885	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IRJ26_RS03890	COG1597	lipid kinase activity
IRJ26_RS03895	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IRJ26_RS03900	COG1309	transcriptional regulator
IRJ26_RS03905	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IRJ26_RS03910	COG0154	amidase activity
IRJ26_RS03915	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IRJ26_RS03920	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IRJ26_RS03925	COG1285	pathogenesis
IRJ26_RS03930	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IRJ26_RS03935	COG4851	CamS sex pheromone cAM373 precursor
IRJ26_RS03940	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IRJ26_RS03945	COG0210	DNA helicase
IRJ26_RS03950	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
IRJ26_RS03955	COG0069	glutamate synthase activity
IRJ26_RS03960	COG4496	protein, YerC YecD
IRJ26_RS03965	COG1470	cell adhesion involved in biofilm formation
IRJ26_RS03970	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IRJ26_RS03980	COG0531	amino acid
IRJ26_RS03985	COG1522	sequence-specific DNA binding
IRJ26_RS03990	COG0151	Belongs to the GarS family
IRJ26_RS03995	COG0138	bifunctional purine biosynthesis protein purh
IRJ26_RS04000	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IRJ26_RS04005	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IRJ26_RS04010	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IRJ26_RS04015	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IRJ26_RS04020	COG0047	phosphoribosylformylglycinamidine synthase activity
IRJ26_RS04025	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IRJ26_RS04030	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IRJ26_RS04035	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IRJ26_RS04040	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IRJ26_RS04045	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IRJ26_RS04055	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
IRJ26_RS04065	COG3064	Membrane
IRJ26_RS04070	COG2252	PERMEase
IRJ26_RS04075	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IRJ26_RS04075	COG0519	Catalyzes the synthesis of GMP from XMP
IRJ26_RS04080	COG1305	Transglutaminase-like
IRJ26_RS04085	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
IRJ26_RS04090	COG0714	Associated with various cellular activities
IRJ26_RS04095	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IRJ26_RS04105	COG1113	amino acid transport
IRJ26_RS04110	COG2132	Multicopper oxidase
IRJ26_RS04120	COG2267	carboxylic ester hydrolase activity
IRJ26_RS04135	COG0823	Involved in the tonB-independent uptake of proteins
IRJ26_RS04140	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IRJ26_RS04145	COG1063	alcohol dehydrogenase
IRJ26_RS04150	COG2814	Major facilitator Superfamily
IRJ26_RS04160	COG4260	virion core protein, lumpy skin disease virus
IRJ26_RS04165	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IRJ26_RS04170	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IRJ26_RS04175	COG1842	Phage shock protein A
IRJ26_RS04180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IRJ26_RS04185	COG2211	Major facilitator Superfamily
IRJ26_RS04190	COG1063	alcohol dehydrogenase
IRJ26_RS04195	COG0457	Tetratricopeptide repeat
IRJ26_RS04215	COG1401	restriction endodeoxyribonuclease activity
IRJ26_RS04230	COG0270	DNA (cytosine-5-)-methyltransferase activity
IRJ26_RS04235	COG0270	DNA (cytosine-5-)-methyltransferase activity
IRJ26_RS04250	COG3378	Phage plasmid primase P4 family
IRJ26_RS04265	COG0459	protein refolding
IRJ26_RS04275	COG1266	CAAX protease self-immunity
IRJ26_RS04285	COG0805	protein transport
IRJ26_RS04290	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IRJ26_RS04295	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IRJ26_RS04300	COG0315	cyclic pyranopterin monophosphate synthase activity
IRJ26_RS04305	COG0488	(ABC) transporter
IRJ26_RS04310	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IRJ26_RS04315	COG0456	acetyltransferase
IRJ26_RS04320	COG1214	PFAM Peptidase M22, glycoprotease
IRJ26_RS04325	COG0802	atpase or kinase
IRJ26_RS04330	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IRJ26_RS04375	COG4124	Belongs to the glycosyl hydrolase 26 family
IRJ26_RS04380	COG1482	cell wall glycoprotein biosynthetic process
IRJ26_RS04385	COG1940	carbohydrate kinase activity
IRJ26_RS04390	COG2188	Transcriptional regulator
IRJ26_RS04395	COG2723	6-phospho-beta-galactosidase activity
IRJ26_RS04400	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IRJ26_RS04405	COG1447	Phosphotransferase system cellobiose-specific component IIA
IRJ26_RS04410	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IRJ26_RS04415	COG2814	Major facilitator Superfamily
IRJ26_RS04420	COG1388	LysM domain
IRJ26_RS04425	COG1078	dGTPase activity
IRJ26_RS04430	COG0454	-acetyltransferase
IRJ26_RS04440	COG5646	InterPro IPR014922
IRJ26_RS04445	COG1785	Belongs to the alkaline phosphatase family
IRJ26_RS04455	COG1819	glycosyl
IRJ26_RS04460	COG1388	LysM domain
IRJ26_RS04460	COG3858	chitin binding
IRJ26_RS04465	COG1802	Transcriptional regulator
IRJ26_RS04470	COG0730	response to heat
IRJ26_RS04475	COG2814	Major facilitator Superfamily
IRJ26_RS04480	COG1846	Transcriptional regulator
IRJ26_RS04485	COG0778	Nitroreductase
IRJ26_RS04490	COG2409	Drug exporters of the RND superfamily
IRJ26_RS04490	COG1033	growth of symbiont in host cell
IRJ26_RS04495	COG1846	Transcriptional regulator
IRJ26_RS04500	COG2318	DinB family
IRJ26_RS04505	COG1113	amino acid transport
IRJ26_RS04510	COG0488	(ABC) transporter
IRJ26_RS04515	COG0456	acetyltransferase
IRJ26_RS04525	COG1309	transcriptional regulator
IRJ26_RS04540	COG0071	Belongs to the small heat shock protein (HSP20) family
IRJ26_RS04545	COG2323	membrane
IRJ26_RS04550	COG2323	membrane
IRJ26_RS04570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IRJ26_RS04575	COG2259	Doxx family
IRJ26_RS04580	COG0346	lactoylglutathione lyase activity
IRJ26_RS04585	COG0778	Nitroreductase
IRJ26_RS04590	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IRJ26_RS04595	COG0789	Transcriptional regulator
IRJ26_RS04595	COG4978	Transcriptional regulator
IRJ26_RS04600	COG1811	Na channel or pump
IRJ26_RS04605	COG0596	Alpha beta hydrolase
IRJ26_RS04610	COG2409	Drug exporters of the RND superfamily
IRJ26_RS04615	COG2197	response regulator
IRJ26_RS04620	COG4585	Histidine kinase
IRJ26_RS04635	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IRJ26_RS04640	COG0640	Transcriptional regulator
IRJ26_RS04645	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IRJ26_RS04650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IRJ26_RS04655	COG0697	spore germination
IRJ26_RS04660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IRJ26_RS04670	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IRJ26_RS04675	COG0640	Transcriptional regulator
IRJ26_RS04680	COG1309	transcriptional regulator
IRJ26_RS04685	COG2814	Major facilitator Superfamily
IRJ26_RS04690	COG2249	NAD(P)H dehydrogenase (quinone) activity
IRJ26_RS04695	COG1733	regulation of RNA biosynthetic process
IRJ26_RS04700	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IRJ26_RS04705	COG1733	regulation of RNA biosynthetic process
IRJ26_RS04710	COG3545	Serine hydrolase
IRJ26_RS04715	COG2030	dehydratase
IRJ26_RS04720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IRJ26_RS04725	COG0697	spore germination
IRJ26_RS04735	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
IRJ26_RS04745	COG0477	Major facilitator Superfamily
IRJ26_RS04750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IRJ26_RS04755	COG2207	Transcriptional regulator
IRJ26_RS04755	COG3708	Transcriptional regulator
IRJ26_RS04760	COG0697	spore germination
IRJ26_RS04765	COG1917	Cupin 2, conserved barrel domain protein
IRJ26_RS04765	COG2207	Transcriptional regulator
IRJ26_RS04780	COG1329	Transcriptional regulator
IRJ26_RS04785	COG1278	Cold shock
IRJ26_RS04790	COG0693	protein deglycase activity
IRJ26_RS04810	COG2814	Major facilitator Superfamily
IRJ26_RS04815	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IRJ26_RS04820	COG1335	isochorismatase
IRJ26_RS04825	COG1522	sequence-specific DNA binding
IRJ26_RS04830	COG1522	sequence-specific DNA binding
IRJ26_RS04835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IRJ26_RS04850	COG0457	Tetratricopeptide repeat
IRJ26_RS04870	COG0741	lytic transglycosylase activity
IRJ26_RS04870	COG0791	NLP P60 protein
IRJ26_RS04875	COG5644	endopeptidase inhibitor activity
IRJ26_RS04885	COG0433	COG0433 Predicted ATPase
IRJ26_RS04920	COG2946	Replication initiation factor
IRJ26_RS04925	COG1674	ftsk spoiiie
IRJ26_RS04955	COG1396	sequence-specific DNA binding
IRJ26_RS04960	COG2856	Zn peptidase
IRJ26_RS04965	COG0582	viral genome integration into host DNA
IRJ26_RS05005	COG3091	SprT-like family
IRJ26_RS05015	COG2183	response to ionizing radiation
IRJ26_RS05020	COG1846	Transcriptional regulator
IRJ26_RS05025	COG1673	EVE domain
IRJ26_RS05045	COG2208	phosphoserine phosphatase activity
IRJ26_RS05050	COG1191	sigma factor activity
IRJ26_RS05055	COG2172	sigma factor antagonist activity
IRJ26_RS05060	COG1366	Belongs to the anti-sigma-factor antagonist family
IRJ26_RS05065	COG2208	phosphoserine phosphatase activity
IRJ26_RS05070	COG2172	sigma factor antagonist activity
IRJ26_RS05075	COG1366	Belongs to the anti-sigma-factor antagonist family
IRJ26_RS05080	COG1366	Belongs to the anti-sigma-factor antagonist family
IRJ26_RS05085	COG2337	Toxic component of a toxin-antitoxin (TA) module
IRJ26_RS05090	COG0864	Transcriptional regulator
IRJ26_RS05095	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IRJ26_RS05100	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IRJ26_RS05105	COG0736	holo-[acyl-carrier-protein] synthase activity
IRJ26_RS05110	COG0705	Rhomboid family
IRJ26_RS05115	COG3428	Bacterial PH domain
IRJ26_RS05120	COG3402	PFAM membrane-flanked domain
IRJ26_RS05125	COG0513	Belongs to the DEAD box helicase family
IRJ26_RS05130	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IRJ26_RS05135	COG1181	Belongs to the D-alanine--D-alanine ligase family
IRJ26_RS05140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IRJ26_RS05145	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IRJ26_RS05160	COG1960	acyl-CoA dehydrogenase activity
IRJ26_RS05170	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
IRJ26_RS05175	COG1131	(ABC) transporter
IRJ26_RS05185	COG0628	permease
IRJ26_RS05190	COG1301	dicarboxylic acid transport
IRJ26_RS05195	COG4565	transcriptional regulatory protein
IRJ26_RS05200	COG3290	protein histidine kinase activity
IRJ26_RS05205	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IRJ26_RS05210	COG3546	catalase activity
IRJ26_RS05215	COG2329	Antibiotic biosynthesis monooxygenase
IRJ26_RS05220	COG0662	Cupin 2, conserved barrel domain protein
IRJ26_RS05225	COG3729	General stress protein
IRJ26_RS05230	COG2217	Heavy metal translocating P-type atpase
IRJ26_RS05235	COG4876	unkown
IRJ26_RS05240	COG2261	transglycosylase associated protein
IRJ26_RS05245	COG1914	H( )-stimulated, divalent metal cation uptake system
IRJ26_RS05260	COG0028	Belongs to the TPP enzyme family
IRJ26_RS05265	COG0494	nUDIX hydrolase
IRJ26_RS05270	COG0531	amino acid
IRJ26_RS05280	COG1215	transferase activity, transferring glycosyl groups
IRJ26_RS05285	COG5298	Protein conserved in bacteria
IRJ26_RS05290	COG3706	GGDEF domain
IRJ26_RS05295	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
IRJ26_RS05300	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IRJ26_RS05300	COG0551	DNA topoisomerase type I activity
IRJ26_RS05305	COG1522	sequence-specific DNA binding
IRJ26_RS05310	COG2814	Major facilitator Superfamily
IRJ26_RS05320	COG3871	stress protein (general stress protein 26)
IRJ26_RS05325	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IRJ26_RS05330	COG1917	Cupin 2, conserved barrel domain protein
IRJ26_RS05335	COG1028	Short-chain dehydrogenase reductase Sdr
IRJ26_RS05340	COG2226	methyltransferase
IRJ26_RS05345	COG0318	PFAM AMP-dependent synthetase and ligase
IRJ26_RS05350	COG3711	transcriptional antiterminator
IRJ26_RS05355	COG4989	oxidoreductase activity
IRJ26_RS05360	COG0768	penicillin binding
IRJ26_RS05365	COG2329	Antibiotic biosynthesis monooxygenase
IRJ26_RS05375	COG2755	lipolytic protein G-D-S-L family
IRJ26_RS05380	COG1414	Transcriptional regulator
IRJ26_RS05385	COG1984	allophanate hydrolase subunit 2
IRJ26_RS05390	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
IRJ26_RS05395	COG4336	lyase activity
IRJ26_RS05400	COG1914	H( )-stimulated, divalent metal cation uptake system
IRJ26_RS05405	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
IRJ26_RS05410	COG0561	phosphatase activity
IRJ26_RS05420	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IRJ26_RS05425	COG0412	Dienelactone hydrolase
IRJ26_RS05430	COG0681	Belongs to the peptidase S26 family
IRJ26_RS05435	COG0473	3-isopropylmalate dehydrogenase activity
IRJ26_RS05440	COG0246	Mannitol dehydrogenase
IRJ26_RS05445	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IRJ26_RS05450	COG2213	PTS system mannitol-specific
IRJ26_RS05460	COG1349	DNA-binding transcription factor activity
IRJ26_RS05465	COG2372	response to copper ion
IRJ26_RS05465	COG1276	copper resistance
IRJ26_RS05470	COG4549	nuclear export factor GLE1
IRJ26_RS05475	COG1028	Short-chain dehydrogenase reductase Sdr
IRJ26_RS05480	COG4975	Glucose uptake
IRJ26_RS05485	COG1012	belongs to the aldehyde dehydrogenase family
IRJ26_RS05490	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IRJ26_RS05495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IRJ26_RS05500	COG0640	Transcriptional regulator
IRJ26_RS05505	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IRJ26_RS05510	COG0778	Nitroreductase
IRJ26_RS05515	COG1309	transcriptional regulator
IRJ26_RS05520	COG2814	Major facilitator Superfamily
IRJ26_RS05525	COG4607	ABC-type enterochelin transport system periplasmic component
IRJ26_RS05530	COG4604	ABC transporter, ATP-binding protein
IRJ26_RS05535	COG4605	iron ion homeostasis
IRJ26_RS05540	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IRJ26_RS05545	COG0527	aspartate kinase activity
IRJ26_RS05565	COG0457	Tetratricopeptide repeat
IRJ26_RS05570	COG3850	Histidine kinase
IRJ26_RS05570	COG5002	protein histidine kinase activity
IRJ26_RS05575	COG0745	RESPONSE REGULATOR receiver
IRJ26_RS05580	COG0577	efflux transmembrane transporter activity
IRJ26_RS05585	COG1136	(ABC) transporter
IRJ26_RS05590	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IRJ26_RS05600	COG0697	spore germination
IRJ26_RS05610	COG5434	Belongs to the glycosyl hydrolase 28 family
IRJ26_RS05615	COG3104	oligopeptide transport
IRJ26_RS05620	COG0596	Alpha beta hydrolase
IRJ26_RS05635	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IRJ26_RS05640	COG0163	prenyltransferase activity
IRJ26_RS05645	COG0583	DNA-binding transcription factor activity
IRJ26_RS05650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IRJ26_RS05655	COG0765	amino acid transport
IRJ26_RS05660	COG1126	abc transporter atp-binding protein
IRJ26_RS05665	COG2364	Membrane
IRJ26_RS05675	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IRJ26_RS05680	COG0697	spore germination
IRJ26_RS05690	COG2814	Major facilitator Superfamily
IRJ26_RS05695	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
IRJ26_RS05700	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IRJ26_RS05705	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IRJ26_RS05725	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IRJ26_RS05730	COG1733	regulation of RNA biosynthetic process
IRJ26_RS05735	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
IRJ26_RS05740	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IRJ26_RS05745	COG0840	transmembrane signaling receptor activity
IRJ26_RS05745	COG3290	protein histidine kinase activity
IRJ26_RS05750	COG3209	COG3209 Rhs family protein
IRJ26_RS05760	COG2723	6-phospho-beta-galactosidase activity
IRJ26_RS05770	COG1714	RDD family
IRJ26_RS05780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IRJ26_RS05785	COG0765	amino acid transport
IRJ26_RS05790	COG0523	cobalamin synthesis protein
IRJ26_RS05800	COG1376	ErfK ybiS ycfS ynhG family protein
IRJ26_RS05805	COG1469	GTP cyclohydrolase I activity
IRJ26_RS05810	COG2223	nitrite transmembrane transporter activity
IRJ26_RS05815	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IRJ26_RS05820	COG0243	molybdopterin cofactor binding
IRJ26_RS05825	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IRJ26_RS05830	COG2146	nitrite reductase [NAD(P)H] activity
IRJ26_RS05835	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IRJ26_RS05835	COG1587	Uroporphyrinogen-III synthase
IRJ26_RS05840	COG0492	ferredoxin-NADP+ reductase activity
IRJ26_RS05845	COG2267	carboxylic ester hydrolase activity
IRJ26_RS05850	COG0701	Predicted permease
IRJ26_RS05855	COG3689	TIGRFAM TIGR03943 family protein
IRJ26_RS05860	COG2508	Transcriptional regulator
IRJ26_RS05870	COG1012	belongs to the aldehyde dehydrogenase family
IRJ26_RS05875	COG0506	proline dehydrogenase activity
IRJ26_RS05880	COG3541	Predicted nucleotidyltransferase
IRJ26_RS05885	COG3458	cephalosporin-C deacetylase activity
IRJ26_RS05890	COG0583	DNA-binding transcription factor activity
IRJ26_RS05895	COG2226	methyltransferase
IRJ26_RS05900	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IRJ26_RS05905	COG1660	Displays ATPase and GTPase activities
IRJ26_RS05910	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IRJ26_RS05915	COG3665	Urea carboxylase-associated protein
IRJ26_RS05920	COG1113	amino acid transport
IRJ26_RS05925	COG3403	YqcI/YcgG family
IRJ26_RS05930	COG1280	lysine exporter protein (LysE YggA)
IRJ26_RS05935	COG1846	Transcriptional regulator
IRJ26_RS05940	COG2814	Major facilitator Superfamily
IRJ26_RS05945	COG1620	l-lactate permease
IRJ26_RS05950	COG0039	L-malate dehydrogenase activity
IRJ26_RS05955	COG0366	Alpha amylase catalytic
IRJ26_RS05965	COG1288	antiporter activity
IRJ26_RS05970	COG1473	amidohydrolase
IRJ26_RS05975	COG2113	Glycine betaine
IRJ26_RS05980	COG4176	ABC-type proline glycine betaine transport system permease component
IRJ26_RS05985	COG0517	IMP dehydrogenase activity
IRJ26_RS05985	COG4175	Glycine betaine
IRJ26_RS05990	COG0640	Transcriptional regulator
IRJ26_RS05995	COG2814	Major facilitator Superfamily
IRJ26_RS06000	COG0477	Major facilitator Superfamily
IRJ26_RS06005	COG3853	Toxic anion resistance protein (TelA)
IRJ26_RS06015	COG0861	Integral membrane protein TerC family
IRJ26_RS06020	COG2310	stress, protein
IRJ26_RS06025	COG2310	stress, protein
IRJ26_RS06030	COG2310	stress, protein
IRJ26_RS06035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IRJ26_RS06040	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IRJ26_RS06045	COG1121	(ABC) transporter
IRJ26_RS06050	COG0803	Belongs to the bacterial solute-binding protein 9 family
IRJ26_RS06055	COG0366	Alpha amylase catalytic
IRJ26_RS06060	COG1028	Short-chain dehydrogenase reductase Sdr
IRJ26_RS06065	COG0457	Tetratricopeptide repeat
IRJ26_RS06070	COG1876	peptidase activity
IRJ26_RS06075	COG1595	DNA-templated transcription, initiation
IRJ26_RS06080	COG1595	DNA-templated transcription, initiation
IRJ26_RS06095	COG0667	Aldo Keto reductase
IRJ26_RS06100	COG1668	transmembrane transport
IRJ26_RS06105	COG4555	ABC transporter
IRJ26_RS06110	COG3279	Response regulator of the LytR AlgR family
IRJ26_RS06115	COG3290	protein histidine kinase activity
IRJ26_RS06120	COG1405	negative regulation of cell septum assembly
IRJ26_RS06120	COG3012	SEC-C Motif Domain Protein
IRJ26_RS06125	COG1714	RDD family
IRJ26_RS06130	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
IRJ26_RS06135	COG0252	asparaginase activity
IRJ26_RS06140	COG1309	transcriptional regulator
IRJ26_RS06145	COG0477	Major facilitator Superfamily
IRJ26_RS06150	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IRJ26_RS06155	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IRJ26_RS06160	COG0805	protein transport
IRJ26_RS06165	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IRJ26_RS06170	COG3540	Alkaline phosphatase
IRJ26_RS06180	COG2304	oxidoreductase activity
IRJ26_RS06185	COG3773	Cell wall hydrolase
IRJ26_RS06205	COG1131	(ABC) transporter
IRJ26_RS06210	COG2205	protein histidine kinase activity
IRJ26_RS06215	COG0745	RESPONSE REGULATOR receiver
IRJ26_RS06220	COG0697	spore germination
IRJ26_RS06230	COG3173	Aminoglycoside phosphotransferase
IRJ26_RS06235	COG2721	sulfolactate sulfo-lyase activity
IRJ26_RS06240	COG2186	Transcriptional regulator
IRJ26_RS06245	COG4948	Mandelate Racemase Muconate Lactonizing
IRJ26_RS06250	COG2271	Major facilitator Superfamily
IRJ26_RS06255	COG1012	belongs to the aldehyde dehydrogenase family
IRJ26_RS06260	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IRJ26_RS06265	COG0784	Response regulator, receiver
IRJ26_RS06270	COG4191	Histidine kinase
IRJ26_RS06275	COG2066	Belongs to the glutaminase family
IRJ26_RS06280	COG1115	amino acid carrier protein
IRJ26_RS06285	COG2040	homocysteine
IRJ26_RS06290	COG0833	amino acid
IRJ26_RS06295	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IRJ26_RS06305	COG2188	Transcriptional regulator
IRJ26_RS06310	COG0363	glucosamine-6-phosphate deaminase activity
IRJ26_RS06315	COG1263	PTS System
IRJ26_RS06315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IRJ26_RS06315	COG2190	(PTS) system
IRJ26_RS06320	COG1301	dicarboxylic acid transport
IRJ26_RS06325	COG1054	Belongs to the UPF0176 family
IRJ26_RS06330	COG2207	Transcriptional regulator
IRJ26_RS06335	COG2312	Erythromycin esterase
IRJ26_RS06345	COG0688	phosphatidylethanolamine metabolic process
IRJ26_RS06350	COG0586	Pfam SNARE associated Golgi protein
IRJ26_RS06355	COG1183	phosphatidylcholine synthase activity
IRJ26_RS06360	COG0596	Alpha beta hydrolase
IRJ26_RS06370	COG3591	Belongs to the peptidase S1B family
IRJ26_RS06375	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IRJ26_RS06380	COG1917	Cupin 2, conserved barrel domain protein
IRJ26_RS06380	COG2207	Transcriptional regulator
IRJ26_RS06385	COG0697	spore germination
IRJ26_RS06390	COG3409	Peptidoglycan-binding domain 1 protein
IRJ26_RS06400	COG2271	Major facilitator Superfamily
IRJ26_RS06405	COG0456	acetyltransferase
IRJ26_RS06405	COG1846	Transcriptional regulator
IRJ26_RS06415	COG2271	Major facilitator Superfamily
IRJ26_RS06420	COG0584	glycerophosphoryl diester phosphodiesterase
IRJ26_RS06425	COG0531	amino acid
IRJ26_RS06435	COG2124	cytochrome p450
IRJ26_RS06440	COG2602	Beta-lactamase
IRJ26_RS06455	COG1113	amino acid transport
IRJ26_RS06470	COG0515	serine threonine protein kinase
IRJ26_RS06480	COG0642	Histidine kinase
IRJ26_RS06485	COG0745	RESPONSE REGULATOR receiver
IRJ26_RS06490	COG0596	Alpha beta hydrolase
IRJ26_RS06495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IRJ26_RS06500	COG1413	lyase activity
IRJ26_RS06510	COG1131	(ABC) transporter
IRJ26_RS06515	COG1266	CAAX protease self-immunity
IRJ26_RS06520	COG0535	radical SAM domain protein
IRJ26_RS06535	COG2814	Major facilitator Superfamily
IRJ26_RS06540	COG0640	Transcriptional regulator
IRJ26_RS06545	COG5609	conserved protein (DUF2294)
IRJ26_RS06555	COG0288	reversible hydration of carbon dioxide
IRJ26_RS06560	COG3002	Belongs to the UPF0753 family
IRJ26_RS06565	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IRJ26_RS06570	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IRJ26_RS06575	COG2169	Transcriptional regulator
IRJ26_RS06580	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IRJ26_RS06590	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IRJ26_RS06595	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IRJ26_RS06600	COG4856	YbbR-like protein
IRJ26_RS06605	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IRJ26_RS06610	COG5662	AntiSigma factor
IRJ26_RS06615	COG1595	DNA-templated transcription, initiation
IRJ26_RS06645	COG1683	Conserved Protein
IRJ26_RS06650	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IRJ26_RS06655	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IRJ26_RS06660	COG1737	Transcriptional regulator
IRJ26_RS06665	COG1263	PTS System
IRJ26_RS06665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IRJ26_RS06670	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IRJ26_RS06675	COG1472	Belongs to the glycosyl hydrolase 3 family
IRJ26_RS06680	COG3876	Protein conserved in bacteria
IRJ26_RS06685	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IRJ26_RS06685	COG2207	Transcriptional regulator
IRJ26_RS06690	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IRJ26_RS06695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IRJ26_RS06700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IRJ26_RS06705	COG2819	hydrolase of the alpha beta superfamily
IRJ26_RS06710	COG0385	Bile acid
IRJ26_RS06715	COG0659	secondary active sulfate transmembrane transporter activity
IRJ26_RS06800	COG0726	polysaccharide deacetylase
IRJ26_RS06805	COG2194	sulfuric ester hydrolase activity
IRJ26_RS06815	COG0489	protein tyrosine kinase activity
IRJ26_RS06820	COG0860	N-Acetylmuramoyl-L-alanine amidase
IRJ26_RS06830	COG2226	methyltransferase
IRJ26_RS06835	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IRJ26_RS06840	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IRJ26_RS06845	COG0101	tRNA pseudouridine synthase activity
IRJ26_RS06850	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IRJ26_RS06855	COG1122	ATPase activity
IRJ26_RS06860	COG1122	ATPase activity
IRJ26_RS06865	COG0203	ribosomal protein L17
IRJ26_RS06870	COG0202	RNA polymerase activity
IRJ26_RS06875	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IRJ26_RS06880	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IRJ26_RS06885	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IRJ26_RS06895	COG2163	COG2163 Ribosomal protein L14E L6E L27E
IRJ26_RS06900	COG0024	Methionine aminopeptidase
IRJ26_RS06905	COG0563	adenylate kinase activity
IRJ26_RS06910	COG0201	protein transport
IRJ26_RS06915	COG0200	Binds to the 23S rRNA
IRJ26_RS06925	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IRJ26_RS06930	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IRJ26_RS06935	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IRJ26_RS06940	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IRJ26_RS06950	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IRJ26_RS06960	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IRJ26_RS06965	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IRJ26_RS06975	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IRJ26_RS06980	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IRJ26_RS06995	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IRJ26_RS07005	COG0088	Forms part of the polypeptide exit tunnel
IRJ26_RS07010	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IRJ26_RS07020	COG0596	Alpha beta hydrolase
IRJ26_RS07025	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IRJ26_RS07030	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IRJ26_RS07035	COG0049	tRNA binding
IRJ26_RS07040	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IRJ26_RS07045	COG1358	cellular component organization or biogenesis
IRJ26_RS07050	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IRJ26_RS07055	COG0085	RNA polymerase activity
IRJ26_RS07060	COG2813	Specifically methylates the guanine in position
IRJ26_RS07070	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IRJ26_RS07075	COG0081	regulation of translation
IRJ26_RS07085	COG0250	Participates in transcription elongation, termination and antitermination
IRJ26_RS07090	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IRJ26_RS07100	COG1595	DNA-templated transcription, initiation
IRJ26_RS07105	COG3688	RNA-binding protein containing a PIN domain
IRJ26_RS07110	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IRJ26_RS07115	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IRJ26_RS07120	COG0215	cysteine-tRNA ligase activity
IRJ26_RS07125	COG1045	serine acetyltransferase
IRJ26_RS07130	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IRJ26_RS07135	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
IRJ26_RS07140	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IRJ26_RS07145	COG4956	integral membrane protein (PIN domain superfamily)
IRJ26_RS07150	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
IRJ26_RS07155	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IRJ26_RS07160	COG0542	response to heat
IRJ26_RS07165	COG3869	Catalyzes the specific phosphorylation of arginine residues in
IRJ26_RS07170	COG3880	PFAM UvrB UvrC protein
IRJ26_RS07175	COG4463	regulation of RNA biosynthetic process
IRJ26_RS07255	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IRJ26_RS07260	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IRJ26_RS07265	COG1396	sequence-specific DNA binding
IRJ26_RS07270	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IRJ26_RS07275	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IRJ26_RS07280	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IRJ26_RS07285	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IRJ26_RS07290	COG0512	Glutamine amidotransferase of anthranilate synthase
IRJ26_RS07295	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IRJ26_RS07300	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IRJ26_RS07305	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IRJ26_RS07310	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IRJ26_RS07315	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IRJ26_RS07320	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IRJ26_RS07325	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
IRJ26_RS07330	COG0037	tRNA processing
IRJ26_RS07335	COG0515	serine threonine protein kinase
IRJ26_RS07340	COG2304	oxidoreductase activity
IRJ26_RS07345	COG2208	phosphoserine phosphatase activity
IRJ26_RS07360	COG1098	S1 RNA binding domain
IRJ26_RS07365	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IRJ26_RS07380	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IRJ26_RS07385	COG3956	TIGRFAM MazG family protein
IRJ26_RS07390	COG2244	polysaccharide biosynthetic process
IRJ26_RS07395	COG2002	toxin-antitoxin pair type II binding
IRJ26_RS07400	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IRJ26_RS07410	COG0193	aminoacyl-tRNA hydrolase activity
IRJ26_RS07415	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IRJ26_RS07420	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IRJ26_RS07425	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IRJ26_RS07430	COG2088	sporulation resulting in formation of a cellular spore
IRJ26_RS07435	COG0251	oxidation-reduction process
IRJ26_RS07440	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IRJ26_RS07445	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IRJ26_RS07455	COG4466	Protein conserved in bacteria
IRJ26_RS07465	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IRJ26_RS07470	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IRJ26_RS07475	COG3583	domain protein
IRJ26_RS07475	COG3584	3D domain protein
IRJ26_RS07480	COG0084	hydrolase, TatD family'
IRJ26_RS07485	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IRJ26_RS07485	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IRJ26_RS07490	COG2002	toxin-antitoxin pair type II binding
IRJ26_RS07495	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IRJ26_RS07500	COG2827	Endonuclease containing a URI domain
IRJ26_RS07505	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
IRJ26_RS07510	COG4467	Involved in initiation control of chromosome replication
IRJ26_RS07515	COG1774	PSP1 C-terminal conserved region
IRJ26_RS07520	COG0470	DNA polymerase III
IRJ26_RS07525	COG1728	Protein conserved in bacteria
IRJ26_RS07530	COG3870	Protein conserved in bacteria
IRJ26_RS07535	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IRJ26_RS07540	COG1982	Orn Lys Arg decarboxylase major
IRJ26_RS07545	COG3853	Toxic anion resistance protein (TelA)
IRJ26_RS07550	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
IRJ26_RS07595	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IRJ26_RS07600	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IRJ26_RS07605	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IRJ26_RS07615	COG0590	tRNA wobble adenosine to inosine editing
IRJ26_RS07620	COG1335	isochorismatase
IRJ26_RS07625	COG1388	LysM domain
IRJ26_RS07625	COG3858	chitin binding
IRJ26_RS07630	COG1428	Deoxynucleoside kinase
IRJ26_RS07635	COG1428	Deoxynucleoside kinase
IRJ26_RS07645	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IRJ26_RS07650	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IRJ26_RS07655	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IRJ26_RS07660	COG1686	Belongs to the peptidase S11 family
IRJ26_RS07665	COG0517	IMP dehydrogenase activity
IRJ26_RS07665	COG0516	GMP reductase activity
IRJ26_RS07700	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IRJ26_RS07705	COG0187	DNA topoisomerase II activity
IRJ26_RS07715	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IRJ26_RS07720	COG2501	S4 domain
IRJ26_RS07725	COG0592	DNA-directed DNA polymerase activity
IRJ26_RS07730	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IRJ26_RS07740	COG0594	ribonuclease P activity
IRJ26_RS07745	COG0706	membrane insertase activity
IRJ26_RS07750	COG1847	R3H domain protein
IRJ26_RS07755	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IRJ26_RS07760	COG0445	tRNA wobble uridine modification
IRJ26_RS07765	COG0357	Ribosomal RNA small subunit methyltransferase G
IRJ26_RS07770	COG1475	DNA binding
IRJ26_RS07780	COG1192	Involved in chromosome partitioning
IRJ26_RS07785	COG1475	DNA binding
IRJ26_RS07795	COG3949	Membrane
IRJ26_RS07800	COG4481	Protein conserved in bacteria
IRJ26_RS07805	COG0243	molybdopterin cofactor binding
IRJ26_RS07810	COG0012	GTP binding
IRJ26_RS07815	COG0360	Binds together with S18 to 16S ribosomal RNA
IRJ26_RS07820	COG0629	single-stranded DNA binding
IRJ26_RS07825	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IRJ26_RS07830	COG0708	Exodeoxyribonuclease III
IRJ26_RS07835	COG1609	Transcriptional regulator
IRJ26_RS07840	COG0346	lactoylglutathione lyase activity
IRJ26_RS07845	COG0110	maltose O-acetyltransferase activity
IRJ26_RS07850	COG0477	Major facilitator Superfamily
IRJ26_RS07850	COG2814	Major facilitator Superfamily
IRJ26_RS07855	COG1266	CAAX protease self-immunity
IRJ26_RS07860	COG1331	Highly conserved protein containing a thioredoxin domain
IRJ26_RS07865	COG0697	spore germination
IRJ26_RS07870	COG0789	Transcriptional regulator
IRJ26_RS07875	COG1331	Highly conserved protein containing a thioredoxin domain
IRJ26_RS07880	COG2814	Major facilitator Superfamily
IRJ26_RS07890	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IRJ26_RS07895	COG2315	Protein conserved in bacteria
IRJ26_RS07900	COG0456	acetyltransferase
IRJ26_RS07905	COG2364	Membrane
IRJ26_RS07910	COG2153	protein acetylation
IRJ26_RS07915	COG1846	Transcriptional regulator
IRJ26_RS07920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IRJ26_RS07935	COG2153	protein acetylation
IRJ26_RS07940	COG0583	DNA-binding transcription factor activity
IRJ26_RS07945	COG2814	Major facilitator Superfamily
IRJ26_RS07950	COG1357	PFAM Pentapeptide repeats (8 copies)
IRJ26_RS07955	COG4319	ketosteroid isomerase
IRJ26_RS07970	COG1131	(ABC) transporter
IRJ26_RS08015	COG2271	Major facilitator Superfamily
IRJ26_RS08030	COG1227	inorganic diphosphatase activity
IRJ26_RS08035	COG1733	regulation of RNA biosynthetic process
IRJ26_RS08040	COG5577	PFAM Coat F domain
IRJ26_RS08050	COG4241	membrane
IRJ26_RS08055	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
IRJ26_RS08060	COG0359	binds to the 23S rRNA
IRJ26_RS08065	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IRJ26_RS08070	COG2807	transmembrane transport
IRJ26_RS08075	COG3093	addiction module antidote protein HigA
IRJ26_RS08090	COG0305	Participates in initiation and elongation during chromosome replication
IRJ26_RS08095	COG0346	lactoylglutathione lyase activity
IRJ26_RS08125	COG0745	RESPONSE REGULATOR receiver
IRJ26_RS08130	COG5002	protein histidine kinase activity
IRJ26_RS08135	COG4863	YycH protein
IRJ26_RS08140	COG4853	Protein conserved in bacteria
IRJ26_RS08145	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
IRJ26_RS08150	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IRJ26_RS08165	COG3829	transcription factor binding
IRJ26_RS08170	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IRJ26_RS08175	COG0833	amino acid
IRJ26_RS08180	COG0010	Belongs to the arginase family
IRJ26_RS08190	COG0457	Tetratricopeptide repeat
IRJ26_RS08195	COG0456	acetyltransferase
IRJ26_RS08200	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
IRJ26_RS08220	COG1063	alcohol dehydrogenase
IRJ26_RS08235	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IRJ26_RS08240	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IRJ26_RS08250	COG5293	efflux transmembrane transporter activity
IRJ26_RS08255	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
IRJ26_RS08265	COG0535	radical SAM domain protein
IRJ26_RS08270	COG1994	Peptidase M50
IRJ26_RS08275	COG1131	(ABC) transporter
IRJ26_RS08290	COG2188	Transcriptional regulator
IRJ26_RS08295	COG1263	PTS System
IRJ26_RS08295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IRJ26_RS08295	COG2190	(PTS) system
IRJ26_RS08305	COG2723	6-phospho-beta-galactosidase activity
IRJ26_RS08310	COG3634	alkyl hydroperoxide reductase activity
IRJ26_RS08315	COG0450	alkyl hydroperoxide reductase
IRJ26_RS08320	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IRJ26_RS08325	COG2610	gluconate transmembrane transporter activity
IRJ26_RS08330	COG1070	Carbohydrate kinase
IRJ26_RS08335	COG1802	Transcriptional regulator
IRJ26_RS08340	COG1929	Belongs to the glycerate kinase type-1 family
IRJ26_RS08345	COG5039	Polysaccharide pyruvyl transferase
IRJ26_RS08350	COG1346	cytolysis
IRJ26_RS08355	COG1380	Effector of murein hydrolase LrgA
IRJ26_RS08360	COG1846	Transcriptional regulator
IRJ26_RS08365	COG1028	Short-chain dehydrogenase reductase Sdr
IRJ26_RS08370	COG1309	transcriptional regulator
IRJ26_RS08375	COG1917	Cupin 2, conserved barrel domain protein
IRJ26_RS08380	COG2311	Membrane
IRJ26_RS08385	COG1714	RDD family
IRJ26_RS08395	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IRJ26_RS08400	COG2814	Major facilitator Superfamily
IRJ26_RS08405	COG0367	asparagine synthase
IRJ26_RS08420	COG2226	methyltransferase
IRJ26_RS08425	COG2850	peptidyl-arginine hydroxylation
IRJ26_RS08430	COG0456	acetyltransferase
IRJ26_RS08435	COG1012	belongs to the aldehyde dehydrogenase family
IRJ26_RS08440	COG1309	transcriptional regulator
IRJ26_RS08445	COG1028	Short-chain dehydrogenase reductase Sdr
IRJ26_RS08455	COG0326	Molecular chaperone. Has ATPase activity
IRJ26_RS08460	COG2814	Major facilitator Superfamily
IRJ26_RS08475	COG0667	Aldo Keto reductase
IRJ26_RS08480	COG1349	DNA-binding transcription factor activity
IRJ26_RS08485	COG1012	belongs to the aldehyde dehydrogenase family
IRJ26_RS08490	COG3718	enzyme involved in inositol metabolism
IRJ26_RS08495	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IRJ26_RS08500	COG3962	Belongs to the TPP enzyme family
IRJ26_RS08505	COG1082	Xylose isomerase domain protein TIM barrel
IRJ26_RS08510	COG2814	Major facilitator Superfamily
IRJ26_RS08515	COG0673	inositol 2-dehydrogenase activity
IRJ26_RS08520	COG1082	Xylose isomerase domain protein TIM barrel
IRJ26_RS08525	COG1082	Xylose isomerase domain protein TIM barrel
IRJ26_RS08530	COG0191	fructose-bisphosphate aldolase activity
IRJ26_RS08535	COG0745	RESPONSE REGULATOR receiver
IRJ26_RS08540	COG2205	protein histidine kinase activity
IRJ26_RS08545	COG1136	(ABC) transporter
IRJ26_RS08550	COG0577	efflux transmembrane transporter activity
IRJ26_RS08555	COG5294	Protein conserved in bacteria
IRJ26_RS08560	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IRJ26_RS08590	COG0561	phosphatase activity
IRJ26_RS08595	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
IRJ26_RS08605	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IRJ26_RS08610	COG0456	acetyltransferase
IRJ26_RS08615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IRJ26_RS08620	COG0765	amino acid transport
IRJ26_RS08625	COG1126	abc transporter atp-binding protein
IRJ26_RS08630	COG1473	amidohydrolase
IRJ26_RS08635	COG2079	MmgE PrpD family protein
IRJ26_RS08640	COG3192	ethanolamine utilization protein
IRJ26_RS08650	COG2390	Transcriptional regulator
IRJ26_RS08655	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IRJ26_RS08660	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IRJ26_RS08665	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
IRJ26_RS08670	COG0833	amino acid
IRJ26_RS08675	COG0010	Belongs to the arginase family
IRJ26_RS08680	COG1228	amidohydrolase
IRJ26_RS08685	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IRJ26_RS08690	COG2986	histidine ammonia-lyase
IRJ26_RS08705	COG3507	Belongs to the glycosyl hydrolase 43 family
IRJ26_RS08720	COG5444	nuclease activity
IRJ26_RS08735	COG1263	PTS System
IRJ26_RS08735	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IRJ26_RS08735	COG2190	(PTS) system
IRJ26_RS08740	COG2723	6-phospho-beta-galactosidase activity
IRJ26_RS08745	COG0589	response to stress
IRJ26_RS08750	COG0697	spore germination
IRJ26_RS08755	COG3209	COG3209 Rhs family protein
IRJ26_RS08815	COG3401	FG-GAP repeat protein
IRJ26_RS08815	COG2755	lipolytic protein G-D-S-L family
IRJ26_RS08820	COG0513	Belongs to the DEAD box helicase family
IRJ26_RS08825	COG2270	Major facilitator Superfamily
IRJ26_RS08835	COG3711	transcriptional antiterminator
IRJ26_RS08840	COG2273	Hydrolase Family 16
IRJ26_RS08845	COG2851	Citrate transporter
IRJ26_RS08850	COG0693	protein deglycase activity
IRJ26_RS08850	COG0753	catalase activity
IRJ26_RS08865	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IRJ26_RS08870	COG0500	methyltransferase
IRJ26_RS08875	COG2610	gluconate transmembrane transporter activity
IRJ26_RS08880	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IRJ26_RS08885	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IRJ26_RS08890	COG1028	Short-chain dehydrogenase reductase Sdr
IRJ26_RS08895	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IRJ26_RS08900	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IRJ26_RS08905	COG4894	glucomannan catabolic process
IRJ26_RS08915	COG2195	Cleaves the N-terminal amino acid of tripeptides
IRJ26_RS08920	COG2197	response regulator
IRJ26_RS08925	COG4585	Histidine kinase
IRJ26_RS08935	COG0583	DNA-binding transcription factor activity
IRJ26_RS08940	COG1881	PFAM PEBP family protein
IRJ26_RS08945	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IRJ26_RS08955	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IRJ26_RS08960	COG1012	belongs to the aldehyde dehydrogenase family
IRJ26_RS08965	COG2508	Transcriptional regulator
IRJ26_RS08970	COG3842	ATPase activity
IRJ26_RS08975	COG0726	polysaccharide deacetylase
IRJ26_RS08985	COG0501	Belongs to the peptidase M48B family
IRJ26_RS08990	COG3493	citrate carrier protein
IRJ26_RS08995	COG1271	oxidase subunit
IRJ26_RS09000	COG1294	oxidase, subunit
IRJ26_RS09005	COG4988	ABC transporter
IRJ26_RS09010	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IRJ26_RS09015	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IRJ26_RS09020	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IRJ26_RS09025	COG1595	DNA-templated transcription, initiation
IRJ26_RS09045	COG1131	(ABC) transporter
IRJ26_RS09050	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
IRJ26_RS09055	COG2814	Major facilitator Superfamily
IRJ26_RS09060	COG0753	catalase activity
IRJ26_RS09065	COG2094	Belongs to the DNA glycosylase MPG family
IRJ26_RS09075	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IRJ26_RS09075	COG3711	transcriptional antiterminator
IRJ26_RS09080	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IRJ26_RS09085	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IRJ26_RS09090	COG1447	Phosphotransferase system cellobiose-specific component IIA
IRJ26_RS09095	COG1486	melibiose metabolic process
IRJ26_RS09100	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IRJ26_RS09105	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
IRJ26_RS09110	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IRJ26_RS09115	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IRJ26_RS09120	COG1696	Membrane protein involved in D-alanine export
IRJ26_RS09125	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IRJ26_RS09140	COG1575	Belongs to the MenA family. Type 1 subfamily
IRJ26_RS09145	COG2357	RelA SpoT domain protein
IRJ26_RS09150	COG2234	aminopeptidase activity
IRJ26_RS09155	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IRJ26_RS09160	COG1846	Transcriptional regulator
IRJ26_RS09165	COG5522	Integral membrane protein (intg_mem_TP0381)
IRJ26_RS09170	COG1442	glycosyl transferase family 8
IRJ26_RS09175	COG3711	transcriptional antiterminator
IRJ26_RS09180	COG1263	PTS System
IRJ26_RS09180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IRJ26_RS09185	COG1404	Belongs to the peptidase S8 family
IRJ26_RS09190	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IRJ26_RS09200	COG0346	lactoylglutathione lyase activity
IRJ26_RS09205	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IRJ26_RS09210	COG4895	conserved protein (DUF2196)
IRJ26_RS09215	COG2814	Major facilitator Superfamily
IRJ26_RS09220	COG1346	cytolysis
IRJ26_RS09225	COG1380	Effector of murein hydrolase LrgA
IRJ26_RS09230	COG0583	DNA-binding transcription factor activity
IRJ26_RS09235	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IRJ26_RS09240	COG0352	thiamine-phosphate diphosphorylase activity
IRJ26_RS09245	COG0672	)-iron permease
IRJ26_RS09250	COG2822	iron ion transport
IRJ26_RS09255	COG2837	iron assimilation
IRJ26_RS09260	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IRJ26_RS09265	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IRJ26_RS09270	COG3162	membrane
IRJ26_RS09280	COG1309	transcriptional regulator
IRJ26_RS09285	COG2246	polysaccharide biosynthetic process
IRJ26_RS09290	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IRJ26_RS09295	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
IRJ26_RS09300	COG2261	transglycosylase associated protein
IRJ26_RS09305	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IRJ26_RS09310	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IRJ26_RS09315	COG1845	cytochrome c oxidase, subunit III
IRJ26_RS09320	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IRJ26_RS09330	COG0772	Belongs to the SEDS family
IRJ26_RS09335	COG0778	Nitroreductase
IRJ26_RS09340	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IRJ26_RS09345	COG1404	Belongs to the peptidase S8 family
IRJ26_RS09355	COG3711	transcriptional antiterminator
IRJ26_RS09360	COG2116	formate transmembrane transporter activity
IRJ26_RS09365	COG1263	PTS System
IRJ26_RS09365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IRJ26_RS09370	COG1621	beta-fructofuranosidase activity
IRJ26_RS09380	COG0351	phosphomethylpyrimidine kinase
IRJ26_RS09385	COG1695	Transcriptional regulator
IRJ26_RS09400	COG1216	Glycosyl transferase, family 2
IRJ26_RS09405	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IRJ26_RS09410	COG1012	belongs to the aldehyde dehydrogenase family
IRJ26_RS09420	COG2233	PERMEase
IRJ26_RS09425	COG2363	Small membrane protein
IRJ26_RS09435	COG0463	Glycosyl transferase, family 2
IRJ26_RS09440	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IRJ26_RS09445	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IRJ26_RS09450	COG0456	acetyltransferase
IRJ26_RS09455	COG2089	acid synthase
IRJ26_RS09460	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
IRJ26_RS09465	COG3980	spore coat polysaccharide biosynthesis protein
IRJ26_RS09470	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IRJ26_RS09475	COG1088	dTDP-glucose 4,6-dehydratase activity
IRJ26_RS09480	COG1091	dTDP-4-dehydrorhamnose reductase activity
IRJ26_RS09485	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
IRJ26_RS09495	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IRJ26_RS09500	COG1012	belongs to the aldehyde dehydrogenase family
IRJ26_RS09505	COG4187	Peptidase family M20/M25/M40
IRJ26_RS09510	COG0833	amino acid
IRJ26_RS09515	COG2814	Major facilitator Superfamily
IRJ26_RS09520	COG0077	Prephenate dehydratase
IRJ26_RS09525	COG1917	Cupin 2, conserved barrel domain protein
IRJ26_RS09530	COG1028	Short-chain dehydrogenase reductase Sdr
IRJ26_RS09535	COG0151	Belongs to the GarS family
IRJ26_RS09540	COG2814	Major facilitator Superfamily
IRJ26_RS09545	COG0436	Aminotransferase
IRJ26_RS09550	COG1028	Short-chain dehydrogenase reductase Sdr
IRJ26_RS09555	COG3253	May function as heme-dependent peroxidase
IRJ26_RS09560	COG0280	phosphate acetyltransferase
IRJ26_RS09565	COG0583	DNA-binding transcription factor activity
IRJ26_RS09570	COG0095	Lipoate-protein ligase
IRJ26_RS09575	COG0697	spore germination
IRJ26_RS09585	COG4844	belongs to the
IRJ26_RS09590	COG1078	dGTPase activity
IRJ26_RS09595	COG3465	dGTPase activity
IRJ26_RS09600	COG1959	2 iron, 2 sulfur cluster binding
IRJ26_RS09605	COG0477	Major facilitator Superfamily
IRJ26_RS09610	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IRJ26_RS09615	COG1846	Transcriptional regulator
IRJ26_RS09620	COG1942	4-Oxalocrotonate Tautomerase
IRJ26_RS09625	COG1994	Peptidase M50
IRJ26_RS09635	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IRJ26_RS09640	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IRJ26_RS09645	COG0010	Belongs to the arginase family
IRJ26_RS09650	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IRJ26_RS09660	COG0457	Tetratricopeptide repeat
IRJ26_RS09670	COG3391	amine dehydrogenase activity
IRJ26_RS09675	COG3391	amine dehydrogenase activity
IRJ26_RS09685	COG0612	Peptidase, M16
IRJ26_RS09690	COG0612	Peptidase, M16
IRJ26_RS09695	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IRJ26_RS09700	COG1131	(ABC) transporter
IRJ26_RS09710	COG0535	radical SAM domain protein
IRJ26_RS09725	COG4506	Protein conserved in bacteria
IRJ26_RS09730	COG0018	arginyl-trna synthetase
IRJ26_RS09735	COG2223	nitrite transmembrane transporter activity
IRJ26_RS09740	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IRJ26_RS09750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IRJ26_RS09755	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IRJ26_RS09760	COG1140	nitrate reductase beta subunit
IRJ26_RS09765	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
IRJ26_RS09770	COG2181	nitrate reductase activity
IRJ26_RS09780	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IRJ26_RS09785	COG1132	(ABC) transporter
IRJ26_RS09790	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IRJ26_RS09800	COG4294	response to UV
IRJ26_RS09805	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IRJ26_RS09810	COG0247	lactate metabolic process
IRJ26_RS09810	COG2181	nitrate reductase activity
IRJ26_RS09815	COG1960	acyl-CoA dehydrogenase activity
IRJ26_RS09820	COG3343	RNA polymerase activity
IRJ26_RS09825	COG0504	CTP synthase activity
IRJ26_RS09830	COG4821	SIS domain
IRJ26_RS09835	COG2204	response regulator
IRJ26_RS09840	COG0191	fructose-bisphosphate aldolase activity
IRJ26_RS09845	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IRJ26_RS09850	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IRJ26_RS09855	COG1494	fructose-1,6-bisphosphatase
IRJ26_RS09865	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IRJ26_RS09875	COG1435	thymidine kinase activity
IRJ26_RS09880	COG0281	malic enzyme
IRJ26_RS09885	COG0679	Auxin Efflux Carrier
IRJ26_RS09890	COG0789	Transcriptional regulator
IRJ26_RS09895	COG0346	lactoylglutathione lyase activity
IRJ26_RS09900	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IRJ26_RS09905	COG2890	protein-(glutamine-N5) methyltransferase activity
IRJ26_RS09925	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IRJ26_RS09930	COG0009	L-threonylcarbamoyladenylate synthase
IRJ26_RS09935	COG1971	Probably functions as a manganese efflux pump
IRJ26_RS09940	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IRJ26_RS09945	COG0698	ribose 5-phosphate isomerase
IRJ26_RS09950	COG4475	Protein of unknown function (DUF436)
IRJ26_RS09955	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IRJ26_RS09960	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IRJ26_RS09970	COG0356	it plays a direct role in the translocation of protons across the membrane
IRJ26_RS09980	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IRJ26_RS09985	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IRJ26_RS09990	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IRJ26_RS09995	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IRJ26_RS10000	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IRJ26_RS10005	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IRJ26_RS10015	COG4836	Membrane
IRJ26_RS10025	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IRJ26_RS10030	COG2385	sporulation resulting in formation of a cellular spore
IRJ26_RS10035	COG2304	oxidoreductase activity
IRJ26_RS10045	COG2304	oxidoreductase activity
IRJ26_RS10055	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IRJ26_RS10060	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IRJ26_RS10065	COG0457	Tetratricopeptide repeat
IRJ26_RS10070	COG1994	Peptidase M50
IRJ26_RS10075	COG3237	CsbD-like
IRJ26_RS10090	COG0831	urea catabolic process
IRJ26_RS10095	COG0832	Belongs to the urease beta subunit family
IRJ26_RS10100	COG0804	urea catabolic process
IRJ26_RS10105	COG1959	2 iron, 2 sulfur cluster binding
IRJ26_RS10110	COG2910	NAD(P)H-binding
IRJ26_RS10120	COG0789	Transcriptional regulator
IRJ26_RS10125	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IRJ26_RS10145	COG1247	-acetyltransferase
IRJ26_RS10150	COG0739	heme binding
IRJ26_RS10160	COG0671	phosphoesterase, PA-phosphatase related
IRJ26_RS10165	COG0347	Belongs to the P(II) protein family
IRJ26_RS10170	COG0004	ammonium transporteR
IRJ26_RS10180	COG1335	isochorismatase
IRJ26_RS10185	COG0477	Major facilitator Superfamily
IRJ26_RS10190	COG1953	Uracil, thiamine, allantoin
IRJ26_RS10195	COG3420	alginic acid biosynthetic process
IRJ26_RS10200	COG2814	Major facilitator Superfamily
IRJ26_RS10205	COG1846	Transcriptional regulator
IRJ26_RS10215	COG1609	Transcriptional regulator
IRJ26_RS10220	COG1077	Cell shape determining protein MreB Mrl
IRJ26_RS10225	COG4786	Flagellar basal body rod
IRJ26_RS10230	COG4786	Flagellar basal body rod
IRJ26_RS10235	COG0457	Tetratricopeptide repeat
IRJ26_RS10240	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IRJ26_RS10245	COG1970	mechanosensitive ion channel activity
IRJ26_RS10250	COG2972	Histidine kinase
IRJ26_RS10250	COG0745	RESPONSE REGULATOR receiver
IRJ26_RS10275	COG0629	single-stranded DNA binding
IRJ26_RS10280	COG1349	DNA-binding transcription factor activity
IRJ26_RS10285	COG0561	phosphatase activity
IRJ26_RS10290	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IRJ26_RS10295	COG4715	Zinc finger, swim domain protein
IRJ26_RS10305	COG3944	biosynthesis protein
IRJ26_RS10310	COG0489	protein tyrosine kinase activity
IRJ26_RS10315	COG4464	protein tyrosine phosphatase activity
IRJ26_RS10320	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IRJ26_RS10325	COG3878	Protein conserved in bacteria
IRJ26_RS10345	COG5444	nuclease activity
IRJ26_RS10350	COG2849	repeat protein
IRJ26_RS10355	COG1515	deoxyribonuclease V activity
IRJ26_RS10360	COG0583	DNA-binding transcription factor activity
IRJ26_RS10365	COG0655	NAD(P)H dehydrogenase (quinone) activity
IRJ26_RS10375	COG2059	Chromate
IRJ26_RS10380	COG2059	Chromate
IRJ26_RS10385	COG1522	sequence-specific DNA binding
IRJ26_RS10390	COG0405	Gamma-glutamyltransferase
IRJ26_RS10400	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IRJ26_RS10410	COG5337	Spore coat protein CotH
IRJ26_RS10425	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IRJ26_RS10430	COG0583	DNA-binding transcription factor activity
IRJ26_RS10435	COG0028	Belongs to the TPP enzyme family
IRJ26_RS10440	COG3527	Alpha-acetolactate decarboxylase
IRJ26_RS10445	COG2249	NAD(P)H dehydrogenase (quinone) activity
IRJ26_RS10455	COG3103	Sh3 type 3 domain protein
IRJ26_RS10460	COG1879	ABC-type sugar transport system periplasmic component
IRJ26_RS10465	COG1172	Belongs to the binding-protein-dependent transport system permease family
IRJ26_RS10470	COG1129	ABC transporter
IRJ26_RS10475	COG1869	D-ribose catabolic process
IRJ26_RS10480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IRJ26_RS10485	COG1609	Transcriptional regulator
IRJ26_RS10490	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IRJ26_RS10500	COG2843	Capsule synthesis protein
IRJ26_RS10510	COG0791	NLP P60 protein
IRJ26_RS10515	COG0561	phosphatase activity
IRJ26_RS10520	COG1316	TRANSCRIPTIONal
IRJ26_RS10525	COG2814	Major facilitator Superfamily
IRJ26_RS10535	COG0814	amino acid
IRJ26_RS10540	COG0697	spore germination
IRJ26_RS10545	COG1482	cell wall glycoprotein biosynthetic process
IRJ26_RS10550	COG4193	domain, Protein
IRJ26_RS10560	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IRJ26_RS10565	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
IRJ26_RS10570	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
IRJ26_RS10575	COG0438	transferase activity, transferring glycosyl groups
IRJ26_RS10580	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IRJ26_RS10585	COG1682	transport, permease protein
IRJ26_RS10590	COG1134	teichoic acid transport
IRJ26_RS10610	COG0463	Glycosyl transferase, family 2
IRJ26_RS10615	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IRJ26_RS10615	COG1215	transferase activity, transferring glycosyl groups
IRJ26_RS10625	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IRJ26_RS10630	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IRJ26_RS10635	COG1316	TRANSCRIPTIONal
IRJ26_RS10645	COG2247	cell wall binding repeat
IRJ26_RS10645	COG2385	sporulation resulting in formation of a cellular spore
IRJ26_RS10650	COG0860	N-Acetylmuramoyl-L-alanine amidase
IRJ26_RS10650	COG2247	cell wall binding repeat
IRJ26_RS10660	COG2244	polysaccharide biosynthetic process
IRJ26_RS10665	COG0297	glycogen (starch) synthase activity
IRJ26_RS10665	COG0438	transferase activity, transferring glycosyl groups
IRJ26_RS10670	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IRJ26_RS10675	COG3307	-O-antigen
IRJ26_RS10680	COG3206	protein involved in exopolysaccharide biosynthesis
IRJ26_RS10685	COG1215	transferase activity, transferring glycosyl groups
IRJ26_RS10690	COG0438	transferase activity, transferring glycosyl groups
IRJ26_RS10695	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IRJ26_RS10700	COG1316	TRANSCRIPTIONal
IRJ26_RS10705	COG1739	Uncharacterized protein family UPF0029
IRJ26_RS10710	COG4585	Histidine kinase
IRJ26_RS10715	COG2197	response regulator
IRJ26_RS10720	COG1307	EDD domain protein, DegV family
IRJ26_RS10725	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IRJ26_RS10735	COG1040	competence protein
IRJ26_RS10745	COG2747	anti-sigma28 factor FlgM
IRJ26_RS10750	COG3418	PFAM FlgN family protein
IRJ26_RS10755	COG4786	Flagellar basal body rod
IRJ26_RS10755	COG1256	bacterial-type flagellum assembly
IRJ26_RS10760	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IRJ26_RS10770	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
IRJ26_RS10775	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IRJ26_RS10780	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IRJ26_RS10785	COG1334	flagellar protein FlaG
IRJ26_RS10790	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IRJ26_RS10795	COG1516	flagellar protein fliS
IRJ26_RS10810	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IRJ26_RS10815	COG0653	protein targeting
IRJ26_RS10825	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IRJ26_RS10830	COG2010	Cytochrome c
IRJ26_RS10835	COG2884	Cell division ATP-binding protein ftsE
IRJ26_RS10840	COG2177	Part of the ABC transporter FtsEX involved in
IRJ26_RS10845	COG0793	Belongs to the peptidase S41A family
IRJ26_RS10845	COG3409	Peptidoglycan-binding domain 1 protein
IRJ26_RS10855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IRJ26_RS10860	COG2814	Major facilitator Superfamily
IRJ26_RS10865	COG1309	transcriptional regulator
IRJ26_RS10870	COG0574	Belongs to the PEP-utilizing enzyme family
IRJ26_RS10870	COG3848	Pyruvate phosphate dikinase
IRJ26_RS10875	COG4897	Protein conserved in bacteria
IRJ26_RS10880	COG0556	nucleotide-excision repair
IRJ26_RS10885	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IRJ26_RS10905	COG3595	metallopeptidase activity
IRJ26_RS10910	COG1983	PspC domain protein
IRJ26_RS10915	COG1950	PFAM Membrane protein of
IRJ26_RS10920	COG2814	Major facilitator Superfamily
IRJ26_RS10925	COG1846	Transcriptional regulator
IRJ26_RS10935	COG2124	cytochrome p450
IRJ26_RS10940	COG1846	Transcriptional regulator
IRJ26_RS10945	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IRJ26_RS10950	COG2188	Transcriptional regulator
IRJ26_RS10955	COG0363	glucosamine-6-phosphate deaminase activity
IRJ26_RS10960	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IRJ26_RS10965	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IRJ26_RS10970	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IRJ26_RS10975	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
IRJ26_RS10980	COG0546	phosphoglycolate phosphatase activity
IRJ26_RS10985	COG0110	maltose O-acetyltransferase activity
IRJ26_RS10990	COG5297	Belongs to the glycosyl hydrolase family 6
IRJ26_RS10995	COG4990	cell redox homeostasis
IRJ26_RS11000	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IRJ26_RS11005	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IRJ26_RS11010	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IRJ26_RS11015	COG0131	Imidazoleglycerol-phosphate dehydratase
IRJ26_RS11020	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IRJ26_RS11025	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IRJ26_RS11030	COG0107	imidazoleglycerol-phosphate synthase activity
IRJ26_RS11035	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IRJ26_RS11035	COG0140	phosphoribosyl-ATP diphosphatase activity
IRJ26_RS11055	COG1132	(ABC) transporter
IRJ26_RS11060	COG0457	Tetratricopeptide repeat
IRJ26_RS11065	COG3883	PFAM NLP P60 protein
IRJ26_RS11065	COG0791	NLP P60 protein
IRJ26_RS11070	COG0492	ferredoxin-NADP+ reductase activity
IRJ26_RS11075	COG1051	belongs to the nudix hydrolase family
IRJ26_RS11080	COG1660	Displays ATPase and GTPase activities
IRJ26_RS11085	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IRJ26_RS11090	COG1481	regulation of sporulation
IRJ26_RS11095	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IRJ26_RS11100	COG2162	N-hydroxyarylamine O-acetyltransferase activity
IRJ26_RS11110	COG0745	RESPONSE REGULATOR receiver
IRJ26_RS11115	COG5002	protein histidine kinase activity
IRJ26_RS11120	COG1136	(ABC) transporter
IRJ26_RS11125	COG0577	efflux transmembrane transporter activity
IRJ26_RS11130	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IRJ26_RS11135	COG0288	reversible hydration of carbon dioxide
IRJ26_RS11140	COG0659	secondary active sulfate transmembrane transporter activity
IRJ26_RS11145	COG1694	Mazg nucleotide pyrophosphohydrolase
IRJ26_RS11150	COG1611	Belongs to the LOG family
IRJ26_RS11155	COG1609	Transcriptional regulator
IRJ26_RS11160	COG0366	Alpha amylase catalytic
IRJ26_RS11165	COG2182	Extracellular solute-binding protein
IRJ26_RS11170	COG1175	transmembrane transport
IRJ26_RS11175	COG3833	ABC-type maltose transport systems, permease component
IRJ26_RS11180	COG5521	maltodextrose utilization protein MalA
IRJ26_RS11185	COG1554	hydrolase, family 65, central catalytic
IRJ26_RS11190	COG0366	Alpha amylase catalytic
IRJ26_RS11195	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IRJ26_RS11200	COG0740	serine-type endopeptidase activity
IRJ26_RS11210	COG3621	Patatin-like phospholipase
IRJ26_RS11215	COG0277	FAD linked oxidase domain protein
IRJ26_RS11225	COG2076	Multidrug Resistance protein
IRJ26_RS11230	COG2076	Multidrug Resistance protein
IRJ26_RS11235	COG1309	transcriptional regulator
IRJ26_RS11240	COG0531	amino acid
IRJ26_RS11245	COG1621	beta-fructofuranosidase activity
IRJ26_RS11250	COG1621	beta-fructofuranosidase activity
IRJ26_RS11255	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IRJ26_RS11260	COG1794	racemase activity, acting on amino acids and derivatives
IRJ26_RS11275	COG3479	Phenolic acid decarboxylase
IRJ26_RS11285	COG2272	Belongs to the type-B carboxylesterase lipase family
IRJ26_RS11290	COG1396	sequence-specific DNA binding
IRJ26_RS11295	COG3944	biosynthesis protein
IRJ26_RS11300	COG0489	protein tyrosine kinase activity
IRJ26_RS11305	COG1086	Polysaccharide biosynthesis protein
IRJ26_RS11310	COG0438	transferase activity, transferring glycosyl groups
IRJ26_RS11315	COG1215	transferase activity, transferring glycosyl groups
IRJ26_RS11320	COG0438	transferase activity, transferring glycosyl groups
IRJ26_RS11330	COG1216	Glycosyl transferase, family 2
IRJ26_RS11335	COG5039	Polysaccharide pyruvyl transferase
IRJ26_RS11340	COG1216	Glycosyl transferase, family 2
IRJ26_RS11345	COG2244	polysaccharide biosynthetic process
IRJ26_RS11350	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IRJ26_RS11355	COG0110	maltose O-acetyltransferase activity
IRJ26_RS11360	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IRJ26_RS11365	COG5039	Polysaccharide pyruvyl transferase
IRJ26_RS11375	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
IRJ26_RS11380	COG1620	l-lactate permease
IRJ26_RS11385	COG2186	Transcriptional regulator
IRJ26_RS11390	COG1609	Transcriptional regulator
IRJ26_RS11395	COG2182	Extracellular solute-binding protein
IRJ26_RS11400	COG1175	transmembrane transport
IRJ26_RS11405	COG3833	ABC-type maltose transport systems, permease component
IRJ26_RS11410	COG1874	Beta-galactosidase
IRJ26_RS11415	COG3867	Arabinogalactan endo-beta-1,4-galactanase
IRJ26_RS11420	COG2208	phosphoserine phosphatase activity
IRJ26_RS11425	COG0596	Alpha beta hydrolase
IRJ26_RS11430	COG1131	(ABC) transporter
IRJ26_RS11435	COG0842	Transport permease protein
IRJ26_RS11440	COG4585	Histidine kinase
IRJ26_RS11445	COG2197	response regulator
IRJ26_RS11450	COG0247	lactate metabolic process
IRJ26_RS11455	COG1139	Iron-sulfur cluster binding protein
IRJ26_RS11460	COG1556	Lactate utilization protein
IRJ26_RS11465	COG3858	chitin binding
IRJ26_RS11470	COG1113	amino acid transport
IRJ26_RS11475	COG0697	spore germination
IRJ26_RS11480	COG0583	DNA-binding transcription factor activity
IRJ26_RS11485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IRJ26_RS11490	COG1609	Transcriptional regulator
IRJ26_RS11495	COG2814	Major facilitator Superfamily
IRJ26_RS11500	COG2390	Transcriptional regulator
IRJ26_RS11505	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IRJ26_RS11510	COG0126	phosphoglycerate kinase activity
IRJ26_RS11515	COG0149	triose-phosphate isomerase activity
IRJ26_RS11520	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IRJ26_RS11525	COG0148	phosphopyruvate hydratase activity
IRJ26_RS11530	COG0456	acetyltransferase
IRJ26_RS11535	COG4640	response to antibiotic
IRJ26_RS11540	COG3064	Membrane
IRJ26_RS11550	COG2095	MarC family integral membrane protein
IRJ26_RS11555	COG1510	regulation of RNA biosynthetic process
IRJ26_RS11560	COG0517	IMP dehydrogenase activity
IRJ26_RS11560	COG1125	glycine betaine transport
IRJ26_RS11565	COG1174	glycine betaine transport
IRJ26_RS11570	COG1732	Glycine betaine
IRJ26_RS11575	COG1174	glycine betaine transport
IRJ26_RS11580	COG0640	Transcriptional regulator
IRJ26_RS11585	COG5658	integral membrane protein
IRJ26_RS11605	COG1510	regulation of RNA biosynthetic process
IRJ26_RS11610	COG0517	IMP dehydrogenase activity
IRJ26_RS11610	COG1125	glycine betaine transport
IRJ26_RS11615	COG1174	glycine betaine transport
IRJ26_RS11620	COG1732	Glycine betaine
IRJ26_RS11625	COG1174	glycine betaine transport
IRJ26_RS11630	COG0840	transmembrane signaling receptor activity
IRJ26_RS11635	COG1733	regulation of RNA biosynthetic process
IRJ26_RS11640	COG1396	sequence-specific DNA binding
IRJ26_RS11645	COG1396	sequence-specific DNA binding
IRJ26_RS11650	COG1476	TRANSCRIPTIONal
IRJ26_RS11655	COG0596	Alpha beta hydrolase
IRJ26_RS11660	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IRJ26_RS11665	COG1647	Serine aminopeptidase, S33
IRJ26_RS11670	COG0557	exoribonuclease II activity
IRJ26_RS11675	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IRJ26_RS11685	COG1028	Short-chain dehydrogenase reductase Sdr
IRJ26_RS11690	COG1309	transcriptional regulator
IRJ26_RS11695	COG2076	Multidrug Resistance protein
IRJ26_RS11705	COG1289	transmembrane transporter activity
IRJ26_RS11710	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IRJ26_RS11715	COG0673	inositol 2-dehydrogenase activity
IRJ26_RS11720	COG1937	Protein conserved in bacteria
IRJ26_RS11725	COG2608	mercury ion transmembrane transporter activity
IRJ26_RS11730	COG2217	Heavy metal translocating P-type atpase
IRJ26_RS11735	COG2217	Heavy metal translocating P-type atpase
IRJ26_RS11740	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IRJ26_RS11745	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
IRJ26_RS11750	COG2860	membrane
IRJ26_RS11755	COG3973	AAA domain
IRJ26_RS11760	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IRJ26_RS11765	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IRJ26_RS11770	COG0025	NhaP-type Na H and K H
IRJ26_RS11780	COG0656	L-ascorbic acid biosynthetic process
IRJ26_RS11785	COG4149	molybdate abc transporter
IRJ26_RS11790	COG0725	ABC transporter, periplasmic molybdate-binding protein
IRJ26_RS11795	COG1910	domain protein
IRJ26_RS11800	COG1368	sulfuric ester hydrolase activity
IRJ26_RS11805	COG1988	membrane-bound metal-dependent
IRJ26_RS11815	COG0531	amino acid
IRJ26_RS11820	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IRJ26_RS11825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IRJ26_RS11830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IRJ26_RS11835	COG1120	ATPase activity
IRJ26_RS11840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IRJ26_RS11845	COG1136	(ABC) transporter
IRJ26_RS11850	COG0577	efflux transmembrane transporter activity
IRJ26_RS11860	COG2140	Oxalate decarboxylase
IRJ26_RS11870	COG1191	sigma factor activity
IRJ26_RS11880	COG0745	RESPONSE REGULATOR receiver
IRJ26_RS11885	COG2205	protein histidine kinase activity
IRJ26_RS11890	COG3386	PFAM SMP-30 Gluconolaconase
IRJ26_RS11895	COG1028	Short-chain dehydrogenase reductase Sdr
IRJ26_RS11900	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IRJ26_RS11905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IRJ26_RS11910	COG1120	ATPase activity
IRJ26_RS11915	COG2096	Adenosyltransferase
IRJ26_RS11920	COG2814	Major facilitator Superfamily
IRJ26_RS11925	COG4758	membrane
IRJ26_RS11930	COG1842	Phage shock protein A
IRJ26_RS11935	COG3595	metallopeptidase activity
IRJ26_RS11940	COG4758	membrane
IRJ26_RS11945	COG4585	Histidine kinase
IRJ26_RS11950	COG2197	response regulator
IRJ26_RS11960	COG0814	amino acid
IRJ26_RS11965	COG0697	spore germination
IRJ26_RS11975	COG0114	fumarate hydratase activity
IRJ26_RS11980	COG1309	transcriptional regulator
IRJ26_RS11990	COG2205	protein histidine kinase activity
IRJ26_RS11990	COG2770	Histidine kinase
IRJ26_RS11995	COG0745	RESPONSE REGULATOR receiver
IRJ26_RS12000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IRJ26_RS12005	COG0783	Belongs to the Dps family
IRJ26_RS12010	COG1028	Short-chain dehydrogenase reductase Sdr
IRJ26_RS12025	COG1120	ATPase activity
IRJ26_RS12035	COG0583	DNA-binding transcription factor activity
IRJ26_RS12045	COG1942	4-Oxalocrotonate Tautomerase
IRJ26_RS12050	COG0477	Major facilitator Superfamily
IRJ26_RS12055	COG1846	Transcriptional regulator
IRJ26_RS12060	COG5577	PFAM Coat F domain
IRJ26_RS12070	COG0506	proline dehydrogenase activity
IRJ26_RS12080	COG1024	Enoyl-CoA hydratase
IRJ26_RS12080	COG1250	3-hydroxyacyl-CoA dehydrogenase
IRJ26_RS12085	COG0183	Belongs to the thiolase family
IRJ26_RS12090	COG1960	acyl-CoA dehydrogenase activity
IRJ26_RS12095	COG1393	Belongs to the ArsC family
IRJ26_RS12100	COG0509	glycine decarboxylation via glycine cleavage system
IRJ26_RS12110	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IRJ26_RS12115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IRJ26_RS12125	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IRJ26_RS12130	COG2011	ABC-type metal ion transport system permease component
IRJ26_RS12135	COG1464	Belongs to the NlpA lipoprotein family
IRJ26_RS12140	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IRJ26_RS12150	COG0396	ATPase activity
IRJ26_RS12155	COG0719	Fe-S assembly protein
IRJ26_RS12160	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IRJ26_RS12165	COG0822	iron-sulfur transferase activity
IRJ26_RS12170	COG0719	Fe-S assembly protein
IRJ26_RS12175	COG0640	Transcriptional regulator
IRJ26_RS12180	COG0346	lactoylglutathione lyase activity
IRJ26_RS12195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IRJ26_RS12200	COG0322	excinuclease ABC activity
IRJ26_RS12205	COG2222	sugar isomerase
IRJ26_RS12210	COG1653	transport
IRJ26_RS12215	COG1175	transmembrane transport
IRJ26_RS12220	COG0395	ABC-type sugar transport system, permease component
IRJ26_RS12225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IRJ26_RS12230	COG2188	Transcriptional regulator
IRJ26_RS12235	COG3842	ATPase activity
IRJ26_RS12240	COG2356	endonuclease I
IRJ26_RS12250	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IRJ26_RS12255	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IRJ26_RS12260	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IRJ26_RS12265	COG2068	MobA-Related Protein
IRJ26_RS12270	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
IRJ26_RS12275	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IRJ26_RS12280	COG2080	2 iron, 2 sulfur cluster binding
IRJ26_RS12290	COG2351	hydroxyisourate hydrolase activity
IRJ26_RS12295	COG3195	allantoin biosynthetic process
IRJ26_RS12295	COG3648	Uricase
IRJ26_RS12300	COG2233	PERMEase
IRJ26_RS12305	COG2233	PERMEase
IRJ26_RS12310	COG2508	Transcriptional regulator
IRJ26_RS12315	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IRJ26_RS12325	COG1801	Protein of unknown function DUF72
IRJ26_RS12330	COG0730	response to heat
IRJ26_RS12335	COG0737	Belongs to the 5'-nucleotidase family
IRJ26_RS12340	COG3377	Domain of unknown function (DUF1805)
IRJ26_RS12350	COG0739	heme binding
IRJ26_RS12355	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IRJ26_RS12365	COG4470	Protein conserved in bacteria
IRJ26_RS12370	COG2445	Protein of unknown function DUF86
IRJ26_RS12375	COG0647	UMP catabolic process
IRJ26_RS12380	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IRJ26_RS12385	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IRJ26_RS12390	COG0460	homoserine dehydrogenase
IRJ26_RS12395	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IRJ26_RS12400	COG0083	homoserine kinase activity
IRJ26_RS12405	COG0823	Involved in the tonB-independent uptake of proteins
IRJ26_RS12405	COG1506	peptidase
IRJ26_RS12405	COG4946	Tricorn protease homolog
IRJ26_RS12410	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
IRJ26_RS12415	COG4837	Protein of unknown function (DUF1462)
IRJ26_RS12420	COG1252	NADH dehydrogenase
IRJ26_RS12425	COG4844	belongs to the
IRJ26_RS12430	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IRJ26_RS12435	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IRJ26_RS12440	COG0316	Belongs to the HesB IscA family
IRJ26_RS12445	COG0456	acetyltransferase
IRJ26_RS12450	COG2808	Putative FMN-binding domain
IRJ26_RS12455	COG0516	GMP reductase activity
IRJ26_RS12465	COG0492	ferredoxin-NADP+ reductase activity
IRJ26_RS12470	COG1252	NADH dehydrogenase
IRJ26_RS12485	COG3584	3D domain protein
IRJ26_RS12490	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
IRJ26_RS12495	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IRJ26_RS12500	COG2056	Na+-H+ antiporter family
IRJ26_RS12505	COG1268	BioY protein
IRJ26_RS12510	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IRJ26_RS12515	COG2819	hydrolase of the alpha beta superfamily
IRJ26_RS12520	COG1028	Short-chain dehydrogenase reductase Sdr
IRJ26_RS12525	COG1169	isochorismate synthase
IRJ26_RS12530	COG1021	2,3-dihydroxybenzoate-AMP ligase
IRJ26_RS12535	COG1535	isochorismatase
IRJ26_RS12535	COG3433	isochorismatase activity
IRJ26_RS12540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IRJ26_RS12545	COG3251	PFAM MbtH domain protein
IRJ26_RS12550	COG5634	Uncharacterized conserved protein (DUF2278)
IRJ26_RS12555	COG0686	Belongs to the AlaDH PNT family
IRJ26_RS12560	COG2508	Transcriptional regulator
IRJ26_RS12560	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IRJ26_RS12565	COG4842	Belongs to the WXG100 family
IRJ26_RS12570	COG5417	Belongs to the EsaB family
IRJ26_RS12575	COG4499	WXG100 protein secretion system (Wss), protein YukC
IRJ26_RS12580	COG0433	COG0433 Predicted ATPase
IRJ26_RS12580	COG1674	ftsk spoiiie
IRJ26_RS12585	COG1511	domain protein
IRJ26_RS12595	COG1028	Short-chain dehydrogenase reductase Sdr
IRJ26_RS12600	COG1418	mRNA catabolic process
IRJ26_RS12615	COG0628	permease
IRJ26_RS12630	COG5506	Protein of unknown function (DUF1694)
IRJ26_RS12635	COG1335	isochorismatase
IRJ26_RS12640	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IRJ26_RS12645	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
IRJ26_RS12665	COG0142	geranyltranstransferase activity
IRJ26_RS12680	COG2197	response regulator
IRJ26_RS12685	COG2050	protein possibly involved in aromatic compounds catabolism
IRJ26_RS12690	COG1320	monovalent cation:proton antiporter activity
IRJ26_RS12695	COG2212	antiporter activity
IRJ26_RS12700	COG1863	multisubunit Na H antiporter MnhE subunit
IRJ26_RS12705	COG0651	ATP synthesis coupled electron transport
IRJ26_RS12710	COG1006	Multisubunit Na H antiporter MnhC subunit
IRJ26_RS12715	COG2111	Na H antiporter
IRJ26_RS12720	COG2111	Na H antiporter
IRJ26_RS12720	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IRJ26_RS12730	COG3493	citrate carrier protein
IRJ26_RS12735	COG1079	Belongs to the binding-protein-dependent transport system permease family
IRJ26_RS12740	COG4603	Belongs to the binding-protein-dependent transport system permease family
IRJ26_RS12745	COG3845	ABC transporter
IRJ26_RS12750	COG1744	ABC transporter substrate-binding protein PnrA-like
IRJ26_RS12755	COG4565	transcriptional regulatory protein
IRJ26_RS12760	COG3290	protein histidine kinase activity
IRJ26_RS12770	COG3011	Protein conserved in bacteria
IRJ26_RS12775	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IRJ26_RS12780	COG2814	Major facilitator Superfamily
IRJ26_RS12790	COG5018	Exonuclease
IRJ26_RS12800	COG2205	protein histidine kinase activity
IRJ26_RS12805	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
IRJ26_RS12815	COG2267	carboxylic ester hydrolase activity
IRJ26_RS12820	COG1522	sequence-specific DNA binding
IRJ26_RS12825	COG0436	Aminotransferase
IRJ26_RS12830	COG1098	S1 RNA binding domain
IRJ26_RS12835	COG2155	Conserved Protein
IRJ26_RS12840	COG1979	alcohol dehydrogenase
IRJ26_RS12845	COG1979	alcohol dehydrogenase
IRJ26_RS12850	COG0166	Belongs to the GPI family
IRJ26_RS12865	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IRJ26_RS12880	COG2738	Putative neutral zinc metallopeptidase
IRJ26_RS12885	COG1253	flavin adenine dinucleotide binding
IRJ26_RS12890	COG0366	Alpha amylase catalytic
IRJ26_RS12900	COG0432	Pfam Uncharacterised protein family UPF0047
IRJ26_RS12915	COG0840	transmembrane signaling receptor activity
IRJ26_RS12920	COG0840	transmembrane signaling receptor activity
IRJ26_RS12925	COG0840	transmembrane signaling receptor activity
IRJ26_RS12930	COG0840	transmembrane signaling receptor activity
IRJ26_RS12935	COG1028	Short-chain dehydrogenase reductase Sdr
IRJ26_RS12935	COG3347	Dehydrogenase
IRJ26_RS12940	COG1349	DNA-binding transcription factor activity
IRJ26_RS12945	COG1070	Carbohydrate kinase
IRJ26_RS12950	COG3254	rhamnose metabolic process
IRJ26_RS12955	COG4806	L-rhamnose isomerase
IRJ26_RS12960	COG0673	inositol 2-dehydrogenase activity
IRJ26_RS12965	COG0628	permease
IRJ26_RS12970	COG1968	undecaprenyl-diphosphatase activity
IRJ26_RS12980	COG5553	Cysteine dioxygenase type I
IRJ26_RS12985	COG0477	Major facilitator Superfamily
IRJ26_RS12990	COG1705	Flagellar rod assembly protein muramidase FlgJ
IRJ26_RS12995	COG4682	membrane
IRJ26_RS13000	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IRJ26_RS13005	COG0569	domain protein
IRJ26_RS13015	COG1510	regulation of RNA biosynthetic process
IRJ26_RS13020	COG1012	belongs to the aldehyde dehydrogenase family
IRJ26_RS13025	COG1454	alcohol dehydrogenase
IRJ26_RS13035	COG2318	DinB family
IRJ26_RS13040	COG1585	Membrane protein implicated in regulation of membrane protease activity
IRJ26_RS13045	COG2268	Band 7 protein
IRJ26_RS13050	COG1247	-acetyltransferase
IRJ26_RS13055	COG3859	Proton-coupled thiamine transporter YuaJ
IRJ26_RS13180	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IRJ26_RS13185	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IRJ26_RS13190	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IRJ26_RS13195	COG0297	glycogen (starch) synthase activity
IRJ26_RS13200	COG0058	SHG alpha-glucan phosphorylase activity
IRJ26_RS13205	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
IRJ26_RS13210	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IRJ26_RS13215	COG0438	transferase activity, transferring glycosyl groups
IRJ26_RS13220	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IRJ26_RS13230	COG0438	transferase activity, transferring glycosyl groups
IRJ26_RS13235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IRJ26_RS13240	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IRJ26_RS13245	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IRJ26_RS13250	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IRJ26_RS13255	COG1169	isochorismate synthase
IRJ26_RS13260	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IRJ26_RS13265	COG0596	Alpha beta hydrolase
IRJ26_RS13270	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IRJ26_RS13275	COG0318	PFAM AMP-dependent synthetase and ligase
IRJ26_RS13280	COG4948	Mandelate Racemase Muconate Lactonizing
IRJ26_RS13285	COG0803	Belongs to the bacterial solute-binding protein 9 family
IRJ26_RS13290	COG1121	(ABC) transporter
IRJ26_RS13295	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IRJ26_RS13295	COG1321	iron dependent repressor
IRJ26_RS13300	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IRJ26_RS13310	COG1294	oxidase, subunit
IRJ26_RS13315	COG1271	oxidase subunit
IRJ26_RS13320	COG0254	rRNA binding
IRJ26_RS13325	COG0288	reversible hydration of carbon dioxide
IRJ26_RS13330	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
IRJ26_RS13335	COG1854	S-ribosylhomocysteine lyase activity
IRJ26_RS13350	COG0783	Belongs to the Dps family
IRJ26_RS13355	COG4824	toxin secretion phage lysis holin
IRJ26_RS13360	COG0494	nUDIX hydrolase
IRJ26_RS13365	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IRJ26_RS13370	COG1116	anion transmembrane transporter activity
IRJ26_RS13375	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IRJ26_RS13380	COG1506	peptidase
IRJ26_RS13390	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IRJ26_RS13395	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IRJ26_RS13400	COG0367	asparagine synthase
IRJ26_RS13405	COG1113	amino acid transport
IRJ26_RS13410	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IRJ26_RS13415	COG2267	carboxylic ester hydrolase activity
IRJ26_RS13425	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
IRJ26_RS13430	COG1242	4 iron, 4 sulfur cluster binding
IRJ26_RS13445	COG1725	Transcriptional regulator
IRJ26_RS13450	COG1131	(ABC) transporter
IRJ26_RS13465	COG1136	(ABC) transporter
IRJ26_RS13470	COG0577	efflux transmembrane transporter activity
IRJ26_RS13475	COG0745	RESPONSE REGULATOR receiver
IRJ26_RS13480	COG2205	protein histidine kinase activity
IRJ26_RS13485	COG1136	(ABC) transporter
IRJ26_RS13490	COG0577	efflux transmembrane transporter activity
IRJ26_RS13495	COG2433	Pfam Transposase IS66
IRJ26_RS13500	COG2814	Major facilitator Superfamily
IRJ26_RS13505	COG1366	Belongs to the anti-sigma-factor antagonist family
IRJ26_RS13505	COG2202	Pas domain
IRJ26_RS13515	COG0495	leucyl-tRNA aminoacylation
IRJ26_RS13520	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IRJ26_RS13525	COG1486	melibiose metabolic process
IRJ26_RS13530	COG0395	ABC-type sugar transport system, permease component
IRJ26_RS13535	COG1175	transmembrane transport
IRJ26_RS13540	COG1653	transport
IRJ26_RS13545	COG1609	Transcriptional regulator
IRJ26_RS13550	COG1073	alpha beta
IRJ26_RS13555	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
IRJ26_RS13560	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IRJ26_RS13565	COG0156	8-amino-7-oxononanoate synthase activity
IRJ26_RS13570	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IRJ26_RS13575	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IRJ26_RS13580	COG2124	cytochrome p450
IRJ26_RS13585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IRJ26_RS13590	COG0395	ABC-type sugar transport system, permease component
IRJ26_RS13595	COG1653	transport
IRJ26_RS13600	COG2207	Transcriptional regulator
IRJ26_RS13605	COG4209	transmembrane transport
IRJ26_RS13610	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
IRJ26_RS13615	COG1653	transport
IRJ26_RS13620	COG0673	inositol 2-dehydrogenase activity
IRJ26_RS13625	COG5578	integral membrane protein
IRJ26_RS13635	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IRJ26_RS13640	COG2081	HI0933 family
IRJ26_RS13645	COG2244	polysaccharide biosynthetic process
IRJ26_RS13650	COG1187	pseudouridine synthase activity
IRJ26_RS13655	COG1349	DNA-binding transcription factor activity
IRJ26_RS13660	COG1131	(ABC) transporter
IRJ26_RS13665	COG4473	ABC transporter
IRJ26_RS13670	COG2252	PERMEase
IRJ26_RS13675	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IRJ26_RS13680	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IRJ26_RS13685	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IRJ26_RS13695	COG1597	lipid kinase activity
IRJ26_RS13700	COG1523	belongs to the glycosyl hydrolase 13 family
IRJ26_RS13705	COG0510	thiamine kinase activity
IRJ26_RS13715	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IRJ26_RS13720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IRJ26_RS13725	COG0281	malic enzyme
IRJ26_RS13730	COG5584	Small secreted protein
IRJ26_RS13735	COG1363	Peptidase, m42
IRJ26_RS13750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IRJ26_RS13755	COG4848	Belongs to the UPF0354 family
IRJ26_RS13760	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IRJ26_RS13765	COG1674	ftsk spoiiie
IRJ26_RS13770	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IRJ26_RS13775	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IRJ26_RS13780	COG4980	gas vesicle protein
IRJ26_RS13785	COG3118	belongs to the thioredoxin family
IRJ26_RS13790	COG1605	Chorismate mutase
IRJ26_RS13790	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
IRJ26_RS13795	COG1609	Transcriptional regulator
IRJ26_RS13800	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IRJ26_RS13805	COG1360	Flagellar Motor Protein
IRJ26_RS13810	COG0123	including yeast histone deacetylase and acetoin utilization protein
IRJ26_RS13815	COG0517	IMP dehydrogenase activity
IRJ26_RS13820	COG0454	-acetyltransferase
IRJ26_RS13825	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IRJ26_RS13830	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IRJ26_RS13835	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IRJ26_RS13840	COG2203	Gaf domain
IRJ26_RS13840	COG2199	diguanylate cyclase activity
IRJ26_RS13845	COG1956	GAF domain-containing protein
IRJ26_RS13850	COG1309	transcriptional regulator
IRJ26_RS13855	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
IRJ26_RS13860	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IRJ26_RS13865	COG1114	Component of the transport system for branched-chain amino acids
IRJ26_RS13870	COG1104	cysteine desulfurase activity
IRJ26_RS13875	COG0301	tRNA thio-modification
IRJ26_RS13885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IRJ26_RS13890	COG1574	metal-dependent hydrolase with the TIM-barrel fold
IRJ26_RS13895	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IRJ26_RS13900	COG0616	signal peptide processing
IRJ26_RS13905	COG1714	RDD family
IRJ26_RS13915	COG3874	Sporulation protein YtfJ
IRJ26_RS13920	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IRJ26_RS13925	COG0827	DNA restriction-modification system
IRJ26_RS13935	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IRJ26_RS13940	COG0521	Mo-molybdopterin cofactor biosynthetic process
IRJ26_RS13945	COG0137	argininosuccinate synthase activity
IRJ26_RS13950	COG0165	Argininosuccinate lyase
IRJ26_RS13955	COG1028	Short-chain dehydrogenase reductase Sdr
IRJ26_RS13960	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IRJ26_RS13965	COG0583	DNA-binding transcription factor activity
IRJ26_RS13970	COG0454	-acetyltransferase
IRJ26_RS13975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IRJ26_RS13980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IRJ26_RS13985	COG0765	amino acid transport
IRJ26_RS13990	COG0765	amino acid transport
IRJ26_RS13995	COG1126	abc transporter atp-binding protein
IRJ26_RS14000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IRJ26_RS14005	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IRJ26_RS14010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IRJ26_RS14015	COG0196	riboflavin kinase activity
IRJ26_RS14020	COG1473	amidohydrolase
IRJ26_RS14025	COG0730	response to heat
IRJ26_RS14030	COG4109	DRTGG domain
IRJ26_RS14040	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IRJ26_RS14060	COG0587	DNA-directed DNA polymerase activity
IRJ26_RS14065	COG0281	malic enzyme
IRJ26_RS14070	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IRJ26_RS14075	COG0825	malonyl-CoA metabolic process
IRJ26_RS14080	COG0205	6-phosphofructokinase activity
IRJ26_RS14085	COG0469	pyruvate kinase activity
IRJ26_RS14090	COG3030	protein affecting phage T7 exclusion by the F plasmid
IRJ26_RS14095	COG0628	permease
IRJ26_RS14100	COG2707	UPF0756 membrane protein
IRJ26_RS14105	COG0372	Belongs to the citrate synthase family
IRJ26_RS14110	COG0538	isocitrate dehydrogenase activity
IRJ26_RS14115	COG0039	L-malate dehydrogenase activity
IRJ26_RS14120	COG0745	RESPONSE REGULATOR receiver
IRJ26_RS14125	COG5002	protein histidine kinase activity
IRJ26_RS14130	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IRJ26_RS14130	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IRJ26_RS14135	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IRJ26_RS14140	COG1971	Probably functions as a manganese efflux pump
IRJ26_RS14145	COG0237	dephospho-CoA kinase activity
IRJ26_RS14150	COG0656	L-ascorbic acid biosynthetic process
IRJ26_RS14155	COG2814	Major facilitator Superfamily
IRJ26_RS14160	COG1733	regulation of RNA biosynthetic process
IRJ26_RS14165	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IRJ26_RS14170	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
IRJ26_RS14175	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IRJ26_RS14180	COG3611	Membrane attachment protein
IRJ26_RS14185	COG1484	DNA-dependent DNA replication
IRJ26_RS14190	COG0398	Pfam SNARE associated Golgi protein
IRJ26_RS14200	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IRJ26_RS14205	COG1011	Hydrolase
IRJ26_RS14210	COG3275	phosphorelay sensor kinase activity
IRJ26_RS14215	COG3279	Response regulator of the LytR AlgR family
IRJ26_RS14220	COG1380	Effector of murein hydrolase LrgA
IRJ26_RS14225	COG1346	cytolysis
IRJ26_RS14235	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IRJ26_RS14240	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IRJ26_RS14245	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IRJ26_RS14250	COG3326	Membrane
IRJ26_RS14260	COG1363	Peptidase, m42
IRJ26_RS14265	COG3507	Belongs to the glycosyl hydrolase 43 family
IRJ26_RS14270	COG2160	L-arabinose isomerase activity
IRJ26_RS14275	COG1069	ribulokinase activity
IRJ26_RS14280	COG0235	Class ii aldolase
IRJ26_RS14285	COG0647	UMP catabolic process
IRJ26_RS14290	COG0371	Dehydrogenase
IRJ26_RS14295	COG1653	transport
IRJ26_RS14300	COG1175	transmembrane transport
IRJ26_RS14305	COG0395	ABC-type sugar transport system, permease component
IRJ26_RS14310	COG3534	alpha-L-arabinofuranosidase
IRJ26_RS14315	COG1966	Carbon starvation protein
IRJ26_RS14325	COG0346	lactoylglutathione lyase activity
IRJ26_RS14330	COG0247	lactate metabolic process
IRJ26_RS14335	COG0277	FAD linked oxidase domain protein
IRJ26_RS14340	COG3835	regulator
IRJ26_RS14350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IRJ26_RS14360	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IRJ26_RS14365	COG0072	phenylalanine-tRNA ligase activity
IRJ26_RS14365	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IRJ26_RS14370	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IRJ26_RS14375	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IRJ26_RS14380	COG1286	toxin biosynthetic process
IRJ26_RS14385	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
IRJ26_RS14385	COG1796	DNA polymerase
IRJ26_RS14390	COG1193	negative regulation of DNA recombination
IRJ26_RS14395	COG3766	membrane
IRJ26_RS14400	COG0318	PFAM AMP-dependent synthetase and ligase
IRJ26_RS14405	COG1309	transcriptional regulator
IRJ26_RS14410	COG1024	Enoyl-CoA hydratase
IRJ26_RS14415	COG2086	electron transfer activity
IRJ26_RS14420	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
IRJ26_RS14425	COG3534	alpha-L-arabinofuranosidase
IRJ26_RS14435	COG3118	belongs to the thioredoxin family
IRJ26_RS14440	COG0322	excinuclease ABC activity
IRJ26_RS14445	COG0527	aspartate kinase activity
IRJ26_RS14450	COG1719	4-vinyl reductase, 4VR
IRJ26_RS14455	COG2009	succinate dehydrogenase
IRJ26_RS14460	COG1053	succinate dehydrogenase
IRJ26_RS14465	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IRJ26_RS14470	COG0824	Thioesterase
IRJ26_RS14475	COG2197	response regulator
IRJ26_RS14480	COG1846	Transcriptional regulator
IRJ26_RS14485	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IRJ26_RS14490	COG5401	PFAM Sporulation and spore germination
IRJ26_RS14495	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IRJ26_RS14500	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IRJ26_RS14505	COG0622	Phosphoesterase
IRJ26_RS14515	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
IRJ26_RS14520	COG0454	-acetyltransferase
IRJ26_RS14530	COG0028	Belongs to the TPP enzyme family
IRJ26_RS14535	COG0440	acetolactate synthase activity
IRJ26_RS14540	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IRJ26_RS14545	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IRJ26_RS14550	COG0473	3-isopropylmalate dehydrogenase activity
IRJ26_RS14555	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IRJ26_RS14560	COG0066	3-isopropylmalate dehydratase activity
IRJ26_RS14565	COG1477	protein flavinylation
IRJ26_RS14565	COG0457	Tetratricopeptide repeat
IRJ26_RS14570	COG0544	peptidyl-prolyl cis-trans isomerase activity
IRJ26_RS14575	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IRJ26_RS14580	COG0470	DNA polymerase III
IRJ26_RS14580	COG1067	ATP-dependent peptidase activity
IRJ26_RS14585	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IRJ26_RS14590	COG0218	Necessary for normal cell division and for the maintenance of normal septation
IRJ26_RS14600	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IRJ26_RS14605	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IRJ26_RS14610	COG0181	hydroxymethylbilane synthase activity
IRJ26_RS14615	COG1587	Uroporphyrinogen-III synthase
IRJ26_RS14620	COG0113	porphobilinogen synthase activity
IRJ26_RS14625	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IRJ26_RS14630	COG1388	LysM domain
IRJ26_RS14645	COG0525	valine-tRNA ligase activity
IRJ26_RS14650	COG0285	dihydrofolate synthase activity
IRJ26_RS14655	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
IRJ26_RS14665	COG0424	maF-like protein
IRJ26_RS14670	COG2003	Belongs to the UPF0758 family
IRJ26_RS14675	COG1077	Cell shape determining protein MreB Mrl
IRJ26_RS14685	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IRJ26_RS14690	COG0850	regulation of cytokinetic process
IRJ26_RS14695	COG2894	cell division
IRJ26_RS14700	COG0739	heme binding
IRJ26_RS14705	COG1994	Peptidase M50
IRJ26_RS14710	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IRJ26_RS14715	COG2868	ribosomal protein
IRJ26_RS14720	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IRJ26_RS14730	COG3290	protein histidine kinase activity
IRJ26_RS14735	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IRJ26_RS14740	COG4492	Belongs to the UPF0735 family
IRJ26_RS14745	COG0077	Prephenate dehydratase
IRJ26_RS14750	COG1827	regulation of RNA biosynthetic process
IRJ26_RS14755	COG1104	cysteine desulfurase activity
IRJ26_RS14760	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IRJ26_RS14765	COG0157	Belongs to the NadC ModD family
IRJ26_RS14770	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IRJ26_RS14775	COG1388	LysM domain
IRJ26_RS14785	COG0217	transcriptional regulatory protein
IRJ26_RS14790	COG1115	amino acid carrier protein
IRJ26_RS14810	COG2112	serine threonine protein kinase
IRJ26_RS14815	COG0673	inositol 2-dehydrogenase activity
IRJ26_RS14820	COG2814	Major facilitator Superfamily
IRJ26_RS14830	COG0632	four-way junction helicase activity
IRJ26_RS14835	COG2255	four-way junction helicase activity
IRJ26_RS14845	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IRJ26_RS14850	COG0343	queuine tRNA-ribosyltransferase activity
IRJ26_RS14855	COG1862	Preprotein translocase
IRJ26_RS14865	COG2323	membrane
IRJ26_RS14870	COG2244	polysaccharide biosynthetic process
IRJ26_RS14880	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IRJ26_RS14880	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IRJ26_RS14885	COG0490	domain, Protein
IRJ26_RS14890	COG5416	Lipopolysaccharide assembly protein A domain
IRJ26_RS14895	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IRJ26_RS14895	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
IRJ26_RS14900	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IRJ26_RS14905	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IRJ26_RS14910	COG1490	D-aminoacyl-tRNA deacylase activity
IRJ26_RS14915	COG0860	N-Acetylmuramoyl-L-alanine amidase
IRJ26_RS14915	COG3103	Sh3 type 3 domain protein
IRJ26_RS14915	COG4991	sh3 domain protein
IRJ26_RS14925	COG0124	histidyl-tRNA synthetase
IRJ26_RS14930	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IRJ26_RS14940	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IRJ26_RS14945	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IRJ26_RS14950	COG1959	2 iron, 2 sulfur cluster binding
IRJ26_RS14955	COG1104	cysteine desulfurase activity
IRJ26_RS14960	COG0482	sulfurtransferase activity
IRJ26_RS14965	COG0457	Tetratricopeptide repeat
IRJ26_RS14970	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IRJ26_RS14975	COG3881	PFAM PRC-barrel domain
IRJ26_RS14990	COG0765	amino acid transport
IRJ26_RS14995	COG0765	amino acid transport
IRJ26_RS15000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IRJ26_RS15005	COG1126	abc transporter atp-binding protein
IRJ26_RS15010	COG0628	permease
IRJ26_RS15015	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IRJ26_RS15020	COG4472	Bacterial protein of unknown function (DUF965)
IRJ26_RS15025	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IRJ26_RS15030	COG3906	Belongs to the UPF0473 family
IRJ26_RS15035	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IRJ26_RS15040	COG4122	O-methyltransferase activity
IRJ26_RS15045	COG0826	peptidase U32
IRJ26_RS15050	COG0826	peptidase U32
IRJ26_RS15055	COG0572	uridine kinase
IRJ26_RS15060	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IRJ26_RS15065	COG0768	penicillin binding
IRJ26_RS15080	COG2226	methyltransferase
IRJ26_RS15085	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IRJ26_RS15090	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IRJ26_RS15095	COG0626	cystathionine gamma-synthase activity
IRJ26_RS15105	COG2427	Protein of unknown function (DUF1641)
IRJ26_RS15110	COG3383	formate dehydrogenase (NAD+) activity
IRJ26_RS15115	COG5609	conserved protein (DUF2294)
IRJ26_RS15120	COG2116	formate transmembrane transporter activity
IRJ26_RS15135	COG2226	methyltransferase
IRJ26_RS15140	COG1309	transcriptional regulator
IRJ26_RS15145	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IRJ26_RS15145	COG2124	cytochrome p450
IRJ26_RS15155	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IRJ26_RS15155	COG2755	lipolytic protein G-D-S-L family
IRJ26_RS15165	COG1595	DNA-templated transcription, initiation
IRJ26_RS15170	COG1378	Sugar-specific transcriptional regulator TrmB
IRJ26_RS15175	COG1280	lysine exporter protein (LysE YggA)
IRJ26_RS15180	COG1113	amino acid transport
IRJ26_RS15190	COG3933	PFAM sigma-54 factor interaction domain-containing protein
IRJ26_RS15190	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
IRJ26_RS15195	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
IRJ26_RS15200	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IRJ26_RS15205	COG3715	PTS system
IRJ26_RS15210	COG3716	PTS system mannose fructose sorbose family IID component
IRJ26_RS15220	COG1621	beta-fructofuranosidase activity
IRJ26_RS15225	COG0693	protein deglycase activity
IRJ26_RS15230	COG1064	alcohol dehydrogenase
IRJ26_RS15240	COG0789	Transcriptional regulator
IRJ26_RS15245	COG5577	PFAM Coat F domain
IRJ26_RS15255	COG1063	alcohol dehydrogenase
IRJ26_RS15260	COG5577	PFAM Coat F domain
IRJ26_RS15270	COG0346	lactoylglutathione lyase activity
IRJ26_RS15280	COG4991	sh3 domain protein
IRJ26_RS15285	COG4991	sh3 domain protein
IRJ26_RS15290	COG0596	Alpha beta hydrolase
IRJ26_RS15295	COG5566	PFAM Mor transcription activator
IRJ26_RS15300	COG3409	Peptidoglycan-binding domain 1 protein
IRJ26_RS15305	COG2828	Protein conserved in bacteria
IRJ26_RS15310	COG0583	DNA-binding transcription factor activity
IRJ26_RS15315	COG2851	Citrate transporter
IRJ26_RS15320	COG0667	Aldo Keto reductase
IRJ26_RS15325	COG1595	DNA-templated transcription, initiation
IRJ26_RS15330	COG3443	Belongs to the bacterial solute-binding protein 9 family
IRJ26_RS15350	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IRJ26_RS15355	COG2070	2-Nitropropane dioxygenase
IRJ26_RS15365	COG2318	DinB family
IRJ26_RS15380	COG1335	isochorismatase
IRJ26_RS15395	COG2124	cytochrome p450
IRJ26_RS15400	COG2732	(Barnase) inhibitor
IRJ26_RS15405	COG1522	sequence-specific DNA binding
IRJ26_RS15410	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IRJ26_RS15415	COG1687	branched-chain amino acid
IRJ26_RS15420	COG1114	Component of the transport system for branched-chain amino acids
IRJ26_RS15430	COG0583	DNA-binding transcription factor activity
IRJ26_RS15435	COG1942	4-Oxalocrotonate Tautomerase
IRJ26_RS15440	COG1230	cation diffusion facilitator family transporter
IRJ26_RS15445	COG2072	flavoprotein involved in K transport
IRJ26_RS15450	COG0583	DNA-binding transcription factor activity
IRJ26_RS15455	COG0697	spore germination
IRJ26_RS15465	COG1253	flavin adenine dinucleotide binding
IRJ26_RS15470	COG0456	acetyltransferase
IRJ26_RS15475	COG2814	Major facilitator Superfamily
IRJ26_RS15480	COG0789	Transcriptional regulator
IRJ26_RS15480	COG4978	Transcriptional regulator
IRJ26_RS15495	COG0662	Cupin 2, conserved barrel domain protein
IRJ26_RS15505	COG1937	Protein conserved in bacteria
IRJ26_RS15510	COG2210	Belongs to the sulfur carrier protein TusA family
IRJ26_RS15520	COG0425	Belongs to the sulfur carrier protein TusA family
IRJ26_RS15520	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IRJ26_RS15535	COG0425	Belongs to the sulfur carrier protein TusA family
IRJ26_RS15540	COG0730	response to heat
IRJ26_RS15550	COG2249	NAD(P)H dehydrogenase (quinone) activity
IRJ26_RS15555	COG0454	-acetyltransferase
IRJ26_RS15565	COG2311	Membrane
IRJ26_RS15570	COG0745	RESPONSE REGULATOR receiver
IRJ26_RS15575	COG0642	Histidine kinase
IRJ26_RS15575	COG5002	protein histidine kinase activity
IRJ26_RS15580	COG3223	Belongs to the PsiE family
IRJ26_RS15605	COG2856	Zn peptidase
IRJ26_RS15610	COG0563	adenylate kinase activity
IRJ26_RS15620	COG3620	sequence-specific DNA binding
IRJ26_RS15625	COG1476	TRANSCRIPTIONal
IRJ26_RS15655	COG5377	YqaJ viral recombinase family
IRJ26_RS15660	COG3723	Recombinational DNA repair protein, rece pathway
IRJ26_RS15665	COG3935	DnaD domain protein
IRJ26_RS15670	COG1484	DNA-dependent DNA replication
IRJ26_RS15680	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
IRJ26_RS15695	COG3677	Transposase
IRJ26_RS15705	COG5484	DNA packaging
IRJ26_RS15710	COG1783	phage Terminase large subunit
IRJ26_RS15715	COG5518	Phage portal protein
IRJ26_RS15720	COG2369	cell adhesion
IRJ26_RS15730	COG0338	D12 class N6 adenine-specific DNA methyltransferase
IRJ26_RS15735	COG4653	Phage capsid family
IRJ26_RS15800	COG3953	SLT domain
IRJ26_RS15800	COG5280	Phage tail tape measure protein TP901
IRJ26_RS15805	COG1652	LysM domain
IRJ26_RS15810	COG4193	domain, Protein
IRJ26_RS15820	COG3628	GPW Gp25 family protein
IRJ26_RS15825	COG3299	homolog of phage Mu protein gp47
IRJ26_RS15830	COG3778	Protein conserved in bacteria
IRJ26_RS15860	COG4824	toxin secretion phage lysis holin
IRJ26_RS15865	COG3409	Peptidoglycan-binding domain 1 protein
IRJ26_RS15865	COG5632	N-Acetylmuramoyl-L-alanine amidase
IRJ26_RS15890	COG5444	nuclease activity
IRJ26_RS15905	COG0457	Tetratricopeptide repeat
IRJ26_RS15910	COG3403	YqcI/YcgG family
IRJ26_RS15915	COG0640	Transcriptional regulator
IRJ26_RS15920	COG0346	lactoylglutathione lyase activity
IRJ26_RS15925	COG0798	PFAM Bile acid sodium symporter
IRJ26_RS15930	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IRJ26_RS15940	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IRJ26_RS15950	COG3209	COG3209 Rhs family protein
IRJ26_RS15960	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
IRJ26_RS15965	COG0398	Pfam SNARE associated Golgi protein
IRJ26_RS15970	COG3409	Peptidoglycan-binding domain 1 protein
IRJ26_RS15970	COG5632	N-Acetylmuramoyl-L-alanine amidase
IRJ26_RS15975	COG2755	lipolytic protein G-D-S-L family
IRJ26_RS15985	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
IRJ26_RS15990	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IRJ26_RS15995	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IRJ26_RS16000	COG1534	Rna-binding protein
IRJ26_RS16005	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IRJ26_RS16010	COG1713	HD superfamily hydrolase involved in NAD metabolism
IRJ26_RS16015	COG0799	negative regulation of ribosome biogenesis
IRJ26_RS16020	COG2226	methyltransferase
IRJ26_RS16025	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IRJ26_RS16030	COG1555	photosystem II stabilization
IRJ26_RS16030	COG1596	polysaccharide export
IRJ26_RS16035	COG2131	deaminase
IRJ26_RS16040	COG0658	competence protein
IRJ26_RS16040	COG2333	competence protein COMEC
IRJ26_RS16055	COG1466	dna polymerase III delta subunit
IRJ26_RS16060	COG0268	Binds directly to 16S ribosomal RNA
IRJ26_RS16065	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IRJ26_RS16070	COG0860	N-Acetylmuramoyl-L-alanine amidase
IRJ26_RS16080	COG0481	GTPase activity
IRJ26_RS16085	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IRJ26_RS16090	COG1420	regulation of RNA biosynthetic process
IRJ26_RS16095	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IRJ26_RS16100	COG0443	Heat shock 70 kDa protein
IRJ26_RS16105	COG0484	heat shock protein binding
IRJ26_RS16110	COG2264	protein methyltransferase activity
IRJ26_RS16115	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IRJ26_RS16120	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IRJ26_RS16125	COG1283	sodium-dependent phosphate transmembrane transporter activity
IRJ26_RS16135	COG1610	YqeY-like protein
IRJ26_RS16140	COG1030	water channel activity
IRJ26_RS16145	COG4864	UPF0365 protein
IRJ26_RS16165	COG1702	phosphate starvation-inducible protein PhoH
IRJ26_RS16170	COG1480	7TM receptor with intracellular HD hydrolase
IRJ26_RS16175	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IRJ26_RS16180	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IRJ26_RS16185	COG0295	cytidine deaminase activity
IRJ26_RS16190	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IRJ26_RS16200	COG1381	Involved in DNA repair and RecF pathway recombination
IRJ26_RS16205	COG0752	glycyl-tRNA synthetase alpha subunit
IRJ26_RS16210	COG0751	glycine-tRNA ligase activity
IRJ26_RS16215	COG0517	IMP dehydrogenase activity
IRJ26_RS16220	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
IRJ26_RS16225	COG1671	Belongs to the UPF0178 family
IRJ26_RS16230	COG0358	DNA primase activity
IRJ26_RS16235	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IRJ26_RS16240	COG2010	Cytochrome c
IRJ26_RS16245	COG2384	SAM-dependent methyltransferase
IRJ26_RS16250	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IRJ26_RS16255	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IRJ26_RS16265	COG0513	Belongs to the DEAD box helicase family
IRJ26_RS16270	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IRJ26_RS16280	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IRJ26_RS16285	COG0735	belongs to the Fur family
IRJ26_RS16290	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
IRJ26_RS16295	COG4709	membrane
IRJ26_RS16300	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IRJ26_RS16305	COG1388	LysM domain
IRJ26_RS16315	COG5521	maltodextrose utilization protein MalA
IRJ26_RS16320	COG2839	Protein conserved in bacteria
IRJ26_RS16325	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IRJ26_RS16330	COG0477	Major facilitator Superfamily
IRJ26_RS16335	COG0768	penicillin binding
IRJ26_RS16340	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IRJ26_RS16345	COG0573	inorganic phosphate transmembrane transporter activity
IRJ26_RS16350	COG0581	inorganic phosphate transmembrane transporter activity
IRJ26_RS16355	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IRJ26_RS16360	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IRJ26_RS16365	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IRJ26_RS16380	COG0438	transferase activity, transferring glycosyl groups
IRJ26_RS16390	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IRJ26_RS16400	COG0457	Tetratricopeptide repeat
IRJ26_RS16400	COG0705	Rhomboid family
IRJ26_RS16405	COG4483	Protein conserved in bacteria
IRJ26_RS16410	COG1940	carbohydrate kinase activity
IRJ26_RS16415	COG1368	sulfuric ester hydrolase activity
IRJ26_RS16420	COG2866	Carboxypeptidase
IRJ26_RS16430	COG0011	TIGRFAM Protein of
IRJ26_RS16440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IRJ26_RS16450	COG1393	Belongs to the ArsC family
IRJ26_RS16460	COG1366	Belongs to the anti-sigma-factor antagonist family
IRJ26_RS16465	COG1253	flavin adenine dinucleotide binding
IRJ26_RS16470	COG0598	Magnesium transport protein CorA
IRJ26_RS16475	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IRJ26_RS16480	COG1459	type II secretion system
IRJ26_RS16485	COG4537	Required for transformation and DNA binding
IRJ26_RS16490	COG4970	Tfp pilus assembly protein FimT
IRJ26_RS16500	COG4940	Competence protein ComGF
IRJ26_RS16525	COG0681	Belongs to the peptidase S26 family
IRJ26_RS16535	COG1396	sequence-specific DNA binding
IRJ26_RS16550	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IRJ26_RS16555	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IRJ26_RS16560	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IRJ26_RS16565	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IRJ26_RS16570	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IRJ26_RS16575	COG0095	Lipoate-protein ligase
IRJ26_RS16580	COG1321	iron dependent repressor
IRJ26_RS16585	COG1752	Esterase of the alpha-beta hydrolase superfamily
IRJ26_RS16595	COG3872	metal-dependent enzyme
IRJ26_RS16605	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IRJ26_RS16610	COG0006	proline dipeptidase activity
IRJ26_RS16615	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IRJ26_RS16625	COG3854	ATPases associated with a variety of cellular activities
IRJ26_RS16665	COG0511	ligase activity, forming carbon-carbon bonds
IRJ26_RS16670	COG0439	Biotin carboxylase
IRJ26_RS16675	COG1302	Protein conserved in bacteria
IRJ26_RS16680	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IRJ26_RS16685	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IRJ26_RS16690	COG1570	exodeoxyribonuclease VII activity
IRJ26_RS16695	COG1722	exodeoxyribonuclease VII activity
IRJ26_RS16700	COG0142	geranyltranstransferase activity
IRJ26_RS16705	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IRJ26_RS16710	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
IRJ26_RS16715	COG1438	arginine binding
IRJ26_RS16720	COG0497	DNA recombination
IRJ26_RS16725	COG0750	zinc metalloprotease
IRJ26_RS16730	COG0745	RESPONSE REGULATOR receiver
IRJ26_RS16735	COG1902	pentaerythritol trinitrate reductase activity
IRJ26_RS16750	COG0860	N-Acetylmuramoyl-L-alanine amidase
IRJ26_RS16755	COG0584	glycerophosphoryl diester phosphodiesterase
IRJ26_RS16760	COG0183	Belongs to the thiolase family
IRJ26_RS16765	COG1250	3-hydroxyacyl-CoA dehydrogenase
IRJ26_RS16770	COG1960	acyl-CoA dehydrogenase activity
IRJ26_RS16775	COG0372	Belongs to the citrate synthase family
IRJ26_RS16780	COG2079	MmgE PrpD family protein
IRJ26_RS16785	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IRJ26_RS16795	COG3829	transcription factor binding
IRJ26_RS16795	COG3290	protein histidine kinase activity
IRJ26_RS16800	COG0280	phosphate acetyltransferase
IRJ26_RS16805	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IRJ26_RS16810	COG3426	butyrate kinase activity
IRJ26_RS16815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IRJ26_RS16820	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IRJ26_RS16825	COG0022	dehydrogenase e1 component
IRJ26_RS16830	COG0508	dehydrogenase complex catalyzes the overall conversion of
IRJ26_RS16835	COG0789	Transcriptional regulator
IRJ26_RS16835	COG4978	Transcriptional regulator
IRJ26_RS16840	COG2814	Major facilitator Superfamily
IRJ26_RS16845	COG1597	lipid kinase activity
IRJ26_RS16855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IRJ26_RS16860	COG0765	amino acid transport
IRJ26_RS16865	COG1126	abc transporter atp-binding protein
IRJ26_RS16870	COG4129	membrane
IRJ26_RS16875	COG1376	ErfK ybiS ycfS ynhG family protein
IRJ26_RS16885	COG0346	lactoylglutathione lyase activity
IRJ26_RS16890	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IRJ26_RS16895	COG2195	Cleaves the N-terminal amino acid of tripeptides
IRJ26_RS16900	COG3361	conserved protein (COG2071)
IRJ26_RS16905	COG0706	membrane insertase activity
IRJ26_RS16915	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IRJ26_RS16920	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IRJ26_RS16925	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IRJ26_RS16930	COG1234	tRNA 3'-trailer cleavage
IRJ26_RS16940	COG0596	Alpha beta hydrolase
IRJ26_RS16945	COG1902	pentaerythritol trinitrate reductase activity
IRJ26_RS16950	COG4187	Peptidase family M20/M25/M40
IRJ26_RS16955	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IRJ26_RS16960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IRJ26_RS16965	COG0300	oxidoreductase activity
IRJ26_RS16970	COG3048	D-serine ammonia-lyase activity
IRJ26_RS16975	COG1072	(Pantothenic acid kinase))
IRJ26_RS16980	COG0346	lactoylglutathione lyase activity
IRJ26_RS16990	COG2211	Major facilitator Superfamily
IRJ26_RS17000	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IRJ26_RS17010	COG0456	acetyltransferase
IRJ26_RS17015	COG2329	Antibiotic biosynthesis monooxygenase
IRJ26_RS17020	COG0456	acetyltransferase
IRJ26_RS17020	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IRJ26_RS17025	COG4918	Iron-sulphur cluster biosynthesis
IRJ26_RS17035	COG1073	alpha beta
IRJ26_RS17045	COG0667	Aldo Keto reductase
IRJ26_RS17055	COG0494	nUDIX hydrolase
IRJ26_RS17060	COG1379	DNA repair
IRJ26_RS17065	COG1396	sequence-specific DNA binding
IRJ26_RS17070	COG0252	asparaginase activity
IRJ26_RS17075	COG1027	Aspartate ammonia-lyase
IRJ26_RS17080	COG1757	Na H antiporter
IRJ26_RS17085	COG0281	malic enzyme
IRJ26_RS17095	COG1300	Membrane
IRJ26_RS17100	COG0735	belongs to the Fur family
IRJ26_RS17110	COG4974	Belongs to the 'phage' integrase family
IRJ26_RS17115	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
IRJ26_RS17120	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IRJ26_RS17125	COG1686	Belongs to the peptidase S11 family
IRJ26_RS17130	COG1366	Belongs to the anti-sigma-factor antagonist family
IRJ26_RS17135	COG2172	sigma factor antagonist activity
IRJ26_RS17140	COG1191	sigma factor activity
IRJ26_RS17160	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IRJ26_RS17175	COG0697	spore germination
IRJ26_RS17180	COG0019	diaminopimelate decarboxylase activity
IRJ26_RS17185	COG4086	secreted protein
IRJ26_RS17190	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IRJ26_RS17205	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
IRJ26_RS17215	COG0681	Belongs to the peptidase S26 family
IRJ26_RS17225	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IRJ26_RS17225	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IRJ26_RS17230	COG0307	riboflavin synthase, alpha
IRJ26_RS17235	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IRJ26_RS17235	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IRJ26_RS17240	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IRJ26_RS17245	COG0456	acetyltransferase
IRJ26_RS17255	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IRJ26_RS17260	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IRJ26_RS17270	COG1686	Belongs to the peptidase S11 family
IRJ26_RS17275	COG2715	membrane protein required for spore maturation
IRJ26_RS17280	COG0700	Nucleoside recognition
IRJ26_RS17285	COG1187	pseudouridine synthase activity
IRJ26_RS17290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IRJ26_RS17295	COG1333	cytochrome c biogenesis protein
IRJ26_RS17300	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IRJ26_RS17305	COG0745	RESPONSE REGULATOR receiver
IRJ26_RS17310	COG5002	protein histidine kinase activity
IRJ26_RS17315	COG1595	DNA-templated transcription, initiation
IRJ26_RS17325	COG0710	3-dehydroquinate dehydratase activity
IRJ26_RS17330	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IRJ26_RS17335	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IRJ26_RS17340	COG1141	Ferredoxin
IRJ26_RS17345	COG4955	Helix-turn-helix domain
IRJ26_RS17350	COG0514	ATP-dependent DNA helicase (RecQ)
IRJ26_RS17355	COG1266	CAAX protease self-immunity
IRJ26_RS17360	COG1388	LysM domain
IRJ26_RS17370	COG1408	metallophosphoesterase
IRJ26_RS17375	COG4862	establishment of competence for transformation
IRJ26_RS17380	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IRJ26_RS17385	COG0492	ferredoxin-NADP+ reductase activity
IRJ26_RS17390	COG2339	peptidase activity
IRJ26_RS17395	COG3409	Peptidoglycan-binding domain 1 protein
IRJ26_RS17395	COG3773	Cell wall hydrolase
IRJ26_RS17400	COG2959	enzyme of heme biosynthesis
IRJ26_RS17405	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
IRJ26_RS17415	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IRJ26_RS17420	COG0539	negative regulation of cytoplasmic translation
IRJ26_RS17425	COG1304	FMN binding
IRJ26_RS17450	COG1160	GTP binding
IRJ26_RS17455	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
IRJ26_RS17470	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
IRJ26_RS17475	COG0776	regulation of translation
IRJ26_RS17480	COG0302	gtp cyclohydrolase
IRJ26_RS17490	COG0142	geranyltranstransferase activity
IRJ26_RS17495	COG2226	methyltransferase
IRJ26_RS17500	COG0142	geranyltranstransferase activity
IRJ26_RS17505	COG0105	UTP biosynthetic process
IRJ26_RS17510	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IRJ26_RS17515	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IRJ26_RS17520	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IRJ26_RS17525	COG4401	Chorismate mutase type I
IRJ26_RS17530	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IRJ26_RS17535	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IRJ26_RS17545	COG0135	phosphoribosylanthranilate isomerase activity
IRJ26_RS17550	COG0133	tryptophan synthase activity
IRJ26_RS17555	COG0159	tryptophan synthase activity
IRJ26_RS17560	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IRJ26_RS17565	COG0287	Prephenate dehydrogenase
IRJ26_RS17570	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IRJ26_RS17575	COG0457	Tetratricopeptide repeat
IRJ26_RS17580	COG5582	Belongs to the UPF0302 family
IRJ26_RS17590	COG0723	plastoquinol--plastocyanin reductase activity
IRJ26_RS17595	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IRJ26_RS17600	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IRJ26_RS17600	COG2010	Cytochrome c
IRJ26_RS17605	COG4347	Protein of unknown function (DUF1405)
IRJ26_RS17615	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IRJ26_RS17620	COG1694	Mazg nucleotide pyrophosphohydrolase
IRJ26_RS17625	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IRJ26_RS17630	COG1803	Methylglyoxal synthase
IRJ26_RS17635	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IRJ26_RS17640	COG0438	transferase activity, transferring glycosyl groups
IRJ26_RS17645	COG0617	tRNA 3'-terminal CCA addition
IRJ26_RS17650	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
IRJ26_RS17650	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
IRJ26_RS17655	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IRJ26_RS17660	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IRJ26_RS17665	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
IRJ26_RS17670	COG1199	ATP-dependent helicase activity
IRJ26_RS17670	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IRJ26_RS17680	COG5353	protein conserved in bacteria
IRJ26_RS17685	COG0436	Aminotransferase
IRJ26_RS17690	COG0017	Asparaginyl-tRNA synthetase
IRJ26_RS17695	COG3935	DnaD domain protein
IRJ26_RS17700	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IRJ26_RS17710	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IRJ26_RS17710	COG4499	WXG100 protein secretion system (Wss), protein YukC
IRJ26_RS17715	COG3331	DNA recombination
IRJ26_RS17750	COG0071	Belongs to the small heat shock protein (HSP20) family
IRJ26_RS17755	COG2190	(PTS) system
IRJ26_RS17760	COG1205	dead DEAH box helicase
IRJ26_RS17760	COG1111	helicase
IRJ26_RS17765	COG3359	exonuclease
IRJ26_RS17780	COG4474	Belongs to the UPF0398 family
IRJ26_RS17795	COG0116	Belongs to the methyltransferase superfamily
IRJ26_RS17810	COG1199	ATP-dependent helicase activity
IRJ26_RS17815	COG1028	Short-chain dehydrogenase reductase Sdr
IRJ26_RS17820	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
IRJ26_RS17825	COG1609	Transcriptional regulator
IRJ26_RS17830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IRJ26_RS17835	COG0800	Aldolase
IRJ26_RS17845	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IRJ26_RS17850	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IRJ26_RS17855	COG2233	PERMEase
IRJ26_RS17860	COG3424	synthase
IRJ26_RS17865	COG1755	Isoprenylcysteine carboxyl methyltransferase
IRJ26_RS17875	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
IRJ26_RS17890	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IRJ26_RS17900	COG0328	RNA-DNA hybrid ribonuclease activity
IRJ26_RS17905	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IRJ26_RS17910	COG0328	RNA-DNA hybrid ribonuclease activity
IRJ26_RS17930	COG1278	Cold shock
IRJ26_RS17940	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IRJ26_RS17945	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
IRJ26_RS17950	COG0386	Belongs to the glutathione peroxidase family
IRJ26_RS17955	COG1418	mRNA catabolic process
IRJ26_RS17960	COG1413	lyase activity
IRJ26_RS17965	COG0129	dihydroxy-acid dehydratase activity
IRJ26_RS17975	COG2521	methyltransferase
IRJ26_RS17975	COG2136	Putative SAM-dependent methyltransferase
IRJ26_RS17985	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IRJ26_RS17990	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IRJ26_RS17995	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IRJ26_RS18000	COG0204	Acyl-transferase
IRJ26_RS18005	COG1272	protein, Hemolysin III
IRJ26_RS18010	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
IRJ26_RS18015	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IRJ26_RS18025	COG1999	signal sequence binding
IRJ26_RS18030	COG2755	lipolytic protein G-D-S-L family
IRJ26_RS18035	COG4698	Protein conserved in bacteria
IRJ26_RS18045	COG0534	Mate efflux family protein
IRJ26_RS18050	COG1846	Transcriptional regulator
IRJ26_RS18055	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IRJ26_RS18060	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IRJ26_RS18065	COG1086	Polysaccharide biosynthesis protein
IRJ26_RS18070	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IRJ26_RS18095	COG2746	aminoglycoside 3-N-acetyltransferase activity
IRJ26_RS18105	COG1525	nuclease
IRJ26_RS18120	COG4282	regulation of fungal-type cell wall biogenesis
IRJ26_RS18125	COG5444	nuclease activity
IRJ26_RS18140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IRJ26_RS18170	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IRJ26_RS18185	COG2274	protein secretion by the type I secretion system
IRJ26_RS18185	COG3271	cysteine-type peptidase activity
IRJ26_RS18190	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IRJ26_RS18195	COG0463	Glycosyl transferase, family 2
IRJ26_RS18200	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
IRJ26_RS18215	COG5632	N-Acetylmuramoyl-L-alanine amidase
IRJ26_RS18230	COG4632	Exopolysaccharide biosynthesis protein
IRJ26_RS18230	COG5434	Belongs to the glycosyl hydrolase 28 family
IRJ26_RS18240	COG2433	Pfam Transposase IS66
IRJ26_RS18250	COG0739	heme binding
IRJ26_RS18250	COG0741	lytic transglycosylase activity
IRJ26_RS18250	COG1196	nuclear chromosome segregation
IRJ26_RS18280	COG0582	viral genome integration into host DNA
IRJ26_RS18380	COG4373	Mu-like prophage FluMu protein gp28
IRJ26_RS18415	COG0776	regulation of translation
IRJ26_RS18430	COG1395	domain, Protein
IRJ26_RS18470	COG3655	Transcriptional regulator
IRJ26_RS18550	COG0582	viral genome integration into host DNA
IRJ26_RS18565	COG3655	Transcriptional regulator
IRJ26_RS18620	COG3645	SOS response
IRJ26_RS18620	COG3646	Phage regulatory protein
IRJ26_RS18640	COG1388	LysM domain
IRJ26_RS18650	COG4474	Belongs to the UPF0398 family
IRJ26_RS18705	COG1793	dna ligase
IRJ26_RS18710	COG2135	peptidase activity
IRJ26_RS18725	COG4195	phage-related replication protein
IRJ26_RS18730	COG3420	alginic acid biosynthetic process
IRJ26_RS18730	COG5434	Belongs to the glycosyl hydrolase 28 family
IRJ26_RS18760	COG2887	Belongs to the helicase family. UvrD subfamily
IRJ26_RS18770	COG0305	Participates in initiation and elongation during chromosome replication
IRJ26_RS18775	COG0358	DNA primase activity
IRJ26_RS18780	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IRJ26_RS18785	COG0587	DNA-directed DNA polymerase activity
IRJ26_RS18790	COG3584	3D domain protein
IRJ26_RS18815	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IRJ26_RS18820	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
IRJ26_RS18830	COG0270	DNA (cytosine-5-)-methyltransferase activity
IRJ26_RS18920	COG1780	Probably involved in ribonucleotide reductase function
IRJ26_RS18950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IRJ26_RS18955	COG0756	dUTP diphosphatase activity
IRJ26_RS18960	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
IRJ26_RS18995	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IRJ26_RS19050	COG3331	DNA recombination
IRJ26_RS19060	COG1086	Polysaccharide biosynthesis protein
IRJ26_RS19065	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
IRJ26_RS19070	COG4641	Protein conserved in bacteria
IRJ26_RS19085	COG0463	Glycosyl transferase, family 2
IRJ26_RS19090	COG0456	acetyltransferase
IRJ26_RS19105	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IRJ26_RS19110	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IRJ26_RS19115	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IRJ26_RS19120	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IRJ26_RS19125	COG0456	acetyltransferase
IRJ26_RS19130	COG1509	lysine 2,3-aminomutase activity
IRJ26_RS19140	COG4479	Belongs to the UPF0346 family
IRJ26_RS19160	COG0671	phosphoesterase, PA-phosphatase related
IRJ26_RS19175	COG0813	purine-nucleoside phosphorylase activity
IRJ26_RS19180	COG1876	peptidase activity
IRJ26_RS19190	COG2226	methyltransferase
IRJ26_RS19195	COG0793	Belongs to the peptidase S41A family
IRJ26_RS19195	COG3409	Peptidoglycan-binding domain 1 protein
IRJ26_RS19200	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IRJ26_RS19210	COG0346	lactoylglutathione lyase activity
IRJ26_RS19215	COG0400	carboxylic ester hydrolase activity
IRJ26_RS19220	COG0778	Nitroreductase
IRJ26_RS19225	COG1733	regulation of RNA biosynthetic process
IRJ26_RS19230	COG1942	4-Oxalocrotonate Tautomerase
IRJ26_RS19235	COG2610	gluconate transmembrane transporter activity
IRJ26_RS19250	COG2962	Rard protein
IRJ26_RS19260	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IRJ26_RS19265	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IRJ26_RS19270	COG1366	Belongs to the anti-sigma-factor antagonist family
IRJ26_RS19275	COG0534	Mate efflux family protein
IRJ26_RS19280	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IRJ26_RS19285	COG1819	glycosyl
IRJ26_RS19290	COG0791	NLP P60 protein
IRJ26_RS19290	COG1388	LysM domain
IRJ26_RS19295	COG2032	superoxide dismutase activity
IRJ26_RS19300	COG0714	Associated with various cellular activities
IRJ26_RS19305	COG4548	von Willebrand factor, type A
IRJ26_RS19310	COG0567	Dehydrogenase, E1 component
IRJ26_RS19315	COG0508	dehydrogenase complex catalyzes the overall conversion of
IRJ26_RS19320	COG0385	Bile acid
IRJ26_RS19325	COG0733	neurotransmitter:sodium symporter activity
IRJ26_RS19330	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IRJ26_RS19335	COG1657	PFAM Prenyltransferase squalene oxidase
IRJ26_RS19340	COG1012	belongs to the aldehyde dehydrogenase family
IRJ26_RS19365	COG0071	Belongs to the small heat shock protein (HSP20) family
IRJ26_RS19380	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IRJ26_RS19385	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IRJ26_RS19395	COG0514	ATP-dependent DNA helicase (RecQ)
IRJ26_RS19400	COG1388	LysM domain
IRJ26_RS19400	COG3584	3D domain protein
IRJ26_RS19405	COG2197	response regulator
IRJ26_RS19410	COG4585	Histidine kinase
IRJ26_RS19415	COG3239	Fatty acid desaturase
IRJ26_RS19420	COG1619	proteins homologs of microcin C7 resistance protein MccF
IRJ26_RS19435	COG2322	membrane
IRJ26_RS19440	COG0741	lytic transglycosylase activity
IRJ26_RS19445	COG0640	Transcriptional regulator
IRJ26_RS19455	COG2378	regulation of single-species biofilm formation
IRJ26_RS19460	COG3708	Transcriptional regulator
IRJ26_RS19465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IRJ26_RS19470	COG1309	transcriptional regulator
IRJ26_RS19475	COG0456	acetyltransferase
IRJ26_RS19480	COG0662	Cupin 2, conserved barrel domain protein
IRJ26_RS19480	COG2207	Transcriptional regulator
IRJ26_RS19485	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IRJ26_RS19490	COG5434	Belongs to the glycosyl hydrolase 28 family
IRJ26_RS19495	COG1231	oxidoreductase activity
IRJ26_RS19500	COG4282	regulation of fungal-type cell wall biogenesis
IRJ26_RS19505	COG5444	nuclease activity
IRJ26_RS19530	COG5290	Psort location Cytoplasmic, score
IRJ26_RS19555	COG0457	Tetratricopeptide repeat
IRJ26_RS19595	COG2135	peptidase activity
IRJ26_RS19615	COG1396	sequence-specific DNA binding
IRJ26_RS19620	COG2314	TM2 domain
IRJ26_RS19625	COG0726	polysaccharide deacetylase
IRJ26_RS19630	COG0574	Belongs to the PEP-utilizing enzyme family
IRJ26_RS19630	COG3848	Pyruvate phosphate dikinase
IRJ26_RS19650	COG2367	Beta-lactamase
IRJ26_RS19655	COG0693	protein deglycase activity
IRJ26_RS19665	COG0697	spore germination
IRJ26_RS19670	COG0583	DNA-binding transcription factor activity
IRJ26_RS19675	COG3739	integral membrane protein
IRJ26_RS19680	COG3655	Transcriptional regulator
IRJ26_RS19690	COG2720	vancomycin resistance protein
IRJ26_RS19710	COG0456	acetyltransferase
IRJ26_RS19725	COG2140	Oxalate decarboxylase
IRJ26_RS19735	COG2135	peptidase activity
IRJ26_RS19740	COG3866	Pectate lyase
IRJ26_RS19745	COG3619	membrane
IRJ26_RS19750	COG4305	rare lipoprotein A
IRJ26_RS19755	COG2368	4-hydroxyphenylacetate
IRJ26_RS19760	COG0840	transmembrane signaling receptor activity
IRJ26_RS19760	COG5278	phosphoserine phosphatase activity
IRJ26_RS19790	COG0243	molybdopterin cofactor binding
IRJ26_RS19795	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IRJ26_RS19800	COG1070	Carbohydrate kinase
IRJ26_RS19805	COG2814	Major facilitator Superfamily
IRJ26_RS19810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IRJ26_RS19820	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IRJ26_RS19825	COG0300	oxidoreductase activity
IRJ26_RS19835	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IRJ26_RS19840	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IRJ26_RS19845	COG0583	DNA-binding transcription factor activity
IRJ26_RS19850	COG0067	glutamate synthase
IRJ26_RS19850	COG0069	glutamate synthase activity
IRJ26_RS19850	COG0070	glutamate synthase
IRJ26_RS19855	COG0493	'glutamate synthase
IRJ26_RS19860	COG0604	alcohol dehydrogenase
IRJ26_RS19865	COG0583	DNA-binding transcription factor activity
IRJ26_RS19870	COG0405	Gamma-glutamyltransferase
IRJ26_RS19875	COG0166	Belongs to the GPI family
IRJ26_RS19880	COG0582	viral genome integration into host DNA
IRJ26_RS19895	COG0534	Mate efflux family protein
IRJ26_RS19900	COG2017	converts alpha-aldose to the beta-anomer
IRJ26_RS19905	COG2027	D-alanyl-D-alanine carboxypeptidase
IRJ26_RS19910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IRJ26_RS19915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IRJ26_RS19920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IRJ26_RS19925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IRJ26_RS19930	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
IRJ26_RS19930	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IRJ26_RS19940	COG1649	PFAM Uncharacterised BCR, COG1649
IRJ26_RS19955	COG1960	acyl-CoA dehydrogenase activity
IRJ26_RS19960	COG0318	PFAM AMP-dependent synthetase and ligase
IRJ26_RS19965	COG0439	Biotin carboxylase
IRJ26_RS19970	COG0511	ligase activity, forming carbon-carbon bonds
IRJ26_RS19975	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IRJ26_RS19980	COG1024	Enoyl-CoA hydratase
IRJ26_RS19985	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IRJ26_RS19990	COG2404	hydrolase activity, acting on ester bonds
IRJ26_RS19995	COG0586	Pfam SNARE associated Golgi protein
IRJ26_RS20000	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IRJ26_RS20005	COG2246	polysaccharide biosynthetic process
IRJ26_RS20010	COG3507	Belongs to the glycosyl hydrolase 43 family
IRJ26_RS20015	COG5520	Belongs to the glycosyl hydrolase 30 family
IRJ26_RS20025	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IRJ26_RS20030	COG1115	amino acid carrier protein
IRJ26_RS20040	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IRJ26_RS20045	COG0187	DNA topoisomerase II activity
IRJ26_RS20050	COG1832	CoA-binding protein
IRJ26_RS20055	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
IRJ26_RS20060	COG4841	protein insertion into membrane
IRJ26_RS20070	COG0824	Thioesterase
IRJ26_RS20090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IRJ26_RS20095	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IRJ26_RS20110	COG0071	Belongs to the small heat shock protein (HSP20) family
IRJ26_RS20120	COG4846	Membrane protein involved in cytochrome C biogenesis
IRJ26_RS20125	COG2201	protein-glutamate methylesterase activity
IRJ26_RS20130	COG0785	Cytochrome C biogenesis protein
IRJ26_RS20140	COG3763	UPF0154 protein
IRJ26_RS20150	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IRJ26_RS20155	COG4224	UPF0291 protein
IRJ26_RS20160	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IRJ26_RS20165	COG1388	LysM domain
IRJ26_RS20170	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IRJ26_RS20180	COG0346	lactoylglutathione lyase activity
IRJ26_RS20190	COG4195	phage-related replication protein
IRJ26_RS20220	COG0531	amino acid
IRJ26_RS20225	COG0697	spore germination
IRJ26_RS20235	COG3832	glyoxalase III activity
IRJ26_RS20250	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IRJ26_RS20275	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IRJ26_RS20290	COG0756	dUTP diphosphatase activity
IRJ26_RS20300	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IRJ26_RS20305	COG2814	Major facilitator Superfamily
IRJ26_RS20310	COG1525	nuclease
IRJ26_RS20320	COG1070	Carbohydrate kinase
IRJ26_RS20325	COG2115	Belongs to the xylose isomerase family
IRJ26_RS20330	COG1940	carbohydrate kinase activity
IRJ26_RS20335	COG3507	Belongs to the glycosyl hydrolase 43 family
IRJ26_RS20340	COG2211	Major facilitator Superfamily
IRJ26_RS20345	COG0135	phosphoribosylanthranilate isomerase activity
IRJ26_RS20375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IRJ26_RS20385	COG4282	regulation of fungal-type cell wall biogenesis
IRJ26_RS20405	COG0174	glutamine synthetase
IRJ26_RS20410	COG0789	Transcriptional regulator
IRJ26_RS20415	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
IRJ26_RS20420	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IRJ26_RS20425	COG0464	growth
IRJ26_RS20430	COG0860	N-Acetylmuramoyl-L-alanine amidase
IRJ26_RS20435	COG4112	unkown
IRJ26_RS20440	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IRJ26_RS20445	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IRJ26_RS20450	COG1780	Probably involved in ribonucleotide reductase function
IRJ26_RS20465	COG1923	regulation of RNA biosynthetic process
IRJ26_RS20470	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IRJ26_RS20485	COG2076	Multidrug Resistance protein
IRJ26_RS20490	COG2076	Multidrug Resistance protein
IRJ26_RS20495	COG1764	response to oxidative stress
IRJ26_RS20500	COG4195	phage-related replication protein
IRJ26_RS20505	COG1404	Belongs to the peptidase S8 family
IRJ26_RS20510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IRJ26_RS20520	COG2124	cytochrome p450
IRJ26_RS20525	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IRJ26_RS20525	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IRJ26_RS20525	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
IRJ26_RS20525	COG3321	synthase
IRJ26_RS20530	COG4221	oxidoreductase activity
IRJ26_RS20530	COG3321	synthase
IRJ26_RS20530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IRJ26_RS20530	COG1028	Short-chain dehydrogenase reductase Sdr
IRJ26_RS20535	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IRJ26_RS20535	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IRJ26_RS20535	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IRJ26_RS20535	COG1028	Short-chain dehydrogenase reductase Sdr
IRJ26_RS20535	COG3321	synthase
IRJ26_RS20540	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IRJ26_RS20540	COG0300	oxidoreductase activity
IRJ26_RS20540	COG3321	synthase
IRJ26_RS20540	COG4221	oxidoreductase activity
IRJ26_RS20545	COG3321	synthase
IRJ26_RS20545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IRJ26_RS20545	COG1028	Short-chain dehydrogenase reductase Sdr
IRJ26_RS20545	COG0300	oxidoreductase activity
IRJ26_RS20545	COG0318	PFAM AMP-dependent synthetase and ligase
IRJ26_RS20550	COG1024	Enoyl-CoA hydratase
IRJ26_RS20555	COG1024	Enoyl-CoA hydratase
IRJ26_RS20560	COG3425	synthase
IRJ26_RS20565	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IRJ26_RS20570	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IRJ26_RS20575	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IRJ26_RS20575	COG2070	2-Nitropropane dioxygenase
IRJ26_RS20580	COG3321	synthase
IRJ26_RS20585	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IRJ26_RS20595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IRJ26_RS20600	COG3226	Transcriptional regulator
IRJ26_RS20615	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IRJ26_RS20620	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IRJ26_RS20630	COG4550	Control of competence regulator ComK, YlbF/YmcA
IRJ26_RS20635	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IRJ26_RS20640	COG0156	8-amino-7-oxononanoate synthase activity
IRJ26_RS20645	COG1063	alcohol dehydrogenase
IRJ26_RS20650	COG2359	stage V sporulation protein S
IRJ26_RS20655	COG1692	metallophosphoesterase
IRJ26_RS20660	COG1418	mRNA catabolic process
IRJ26_RS20665	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IRJ26_RS20670	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IRJ26_RS20675	COG1546	Belongs to the CinA family
IRJ26_RS20675	COG1058	Belongs to the CinA family
IRJ26_RS20680	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IRJ26_RS20685	COG1426	Protein conserved in bacteria
IRJ26_RS20700	COG0300	oxidoreductase activity
IRJ26_RS20705	COG0612	Peptidase, M16
IRJ26_RS20710	COG0612	Peptidase, M16
IRJ26_RS20715	COG2814	Major facilitator Superfamily
IRJ26_RS20720	COG2188	Transcriptional regulator
IRJ26_RS20725	COG1674	ftsk spoiiie
IRJ26_RS20725	COG4980	gas vesicle protein
IRJ26_RS20735	COG0740	serine-type endopeptidase activity
IRJ26_RS20740	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IRJ26_RS20745	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IRJ26_RS20750	COG0527	aspartate kinase activity
IRJ26_RS20755	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IRJ26_RS20760	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IRJ26_RS20765	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IRJ26_RS20770	COG1873	PFAM PRC-barrel domain
IRJ26_RS20775	COG0612	Peptidase, M16
IRJ26_RS20780	COG0726	polysaccharide deacetylase
IRJ26_RS20785	COG1185	polyribonucleotide nucleotidyltransferase activity
IRJ26_RS20790	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IRJ26_RS20795	COG0196	riboflavin kinase activity
IRJ26_RS20800	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IRJ26_RS20805	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IRJ26_RS20810	COG1550	Protein conserved in bacteria
IRJ26_RS20815	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IRJ26_RS20820	COG1358	cellular component organization or biogenesis
IRJ26_RS20825	COG2740	Nucleic-acid-binding protein implicated in transcription termination
IRJ26_RS20830	COG0195	Participates in both transcription termination and antitermination
IRJ26_RS20835	COG0779	Required for maturation of 30S ribosomal subunits
IRJ26_RS20840	COG2176	DNA-directed DNA polymerase activity
IRJ26_RS20845	COG0442	prolyl-tRNA aminoacylation
IRJ26_RS20850	COG0750	zinc metalloprotease
IRJ26_RS20855	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
IRJ26_RS20860	COG4589	Belongs to the CDS family
IRJ26_RS20865	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IRJ26_RS20870	COG0233	cytoplasmic translational termination
IRJ26_RS20875	COG0528	UMP kinase activity
IRJ26_RS20880	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IRJ26_RS20885	COG0052	Belongs to the universal ribosomal protein uS2 family
IRJ26_RS20895	COG1191	sigma factor activity
IRJ26_RS20900	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
IRJ26_RS20905	COG1776	CheC inhibitor of MCP methylation
IRJ26_RS20910	COG0835	chemotaxis
IRJ26_RS20915	COG0643	Histidine kinase
IRJ26_RS20915	COG2198	Histidine kinase
IRJ26_RS20920	COG2201	protein-glutamate methylesterase activity
IRJ26_RS20925	COG0455	bacterial-type flagellum organization
IRJ26_RS20930	COG1419	protein localization to endoplasmic reticulum
IRJ26_RS20935	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IRJ26_RS20940	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IRJ26_RS20945	COG1684	flagellar biosynthetic protein fliR
IRJ26_RS20950	COG1987	bacterial-type flagellum assembly
IRJ26_RS20955	COG1338	Plays a role in the flagellum-specific transport system
IRJ26_RS20960	COG3190	flagellar
IRJ26_RS20965	COG2201	protein-glutamate methylesterase activity
IRJ26_RS20970	COG1776	CheC inhibitor of MCP methylation
IRJ26_RS20970	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IRJ26_RS20975	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IRJ26_RS20980	COG1580	Controls the rotational direction of flagella during chemotaxis
IRJ26_RS20985	COG1582	Flagellar protein (FlbD)
IRJ26_RS20990	COG4786	Flagellar basal body rod
IRJ26_RS20995	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
IRJ26_RS21000	COG3144	bacterial-type flagellum assembly
IRJ26_RS21005	COG3334	PFAM MgtE intracellular
IRJ26_RS21010	COG2882	bacterial-type flagellum organization
IRJ26_RS21015	COG1157	protein secretion by the type III secretion system
IRJ26_RS21020	COG1317	bacterial-type flagellum organization
IRJ26_RS21025	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IRJ26_RS21035	COG1677	Flagellar hook-basal body complex protein FliE
IRJ26_RS21040	COG1558	bacterial-type flagellum-dependent cell motility
IRJ26_RS21045	COG1815	bacterial-type flagellum-dependent cell motility
IRJ26_RS21050	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IRJ26_RS21055	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IRJ26_RS21060	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IRJ26_RS21065	COG4974	Belongs to the 'phage' integrase family
IRJ26_RS21070	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IRJ26_RS21075	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IRJ26_RS21080	COG0758	DNA mediated transformation
IRJ26_RS21085	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IRJ26_RS21090	COG0045	succinate-CoA ligase (ADP-forming) activity
IRJ26_RS21095	COG2257	FlhB HrpN YscU SpaS Family
IRJ26_RS21105	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IRJ26_RS21110	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IRJ26_RS21115	COG0335	large ribosomal subunit rRNA binding
IRJ26_RS21120	COG0336	Belongs to the RNA methyltransferase TrmD family
IRJ26_RS21125	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IRJ26_RS21135	COG1837	Belongs to the UPF0109 family
IRJ26_RS21140	COG0228	four-way junction DNA binding
IRJ26_RS21145	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IRJ26_RS21150	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IRJ26_RS21160	COG0552	protein localization to endoplasmic reticulum
IRJ26_RS21165	COG1196	nuclear chromosome segregation
IRJ26_RS21170	COG0571	ribonuclease III activity
IRJ26_RS21180	COG1028	Short-chain dehydrogenase reductase Sdr
IRJ26_RS21185	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IRJ26_RS21190	COG0416	fatty acid biosynthetic process
IRJ26_RS21195	COG1349	DNA-binding transcription factor activity
IRJ26_RS21195	COG2050	protein possibly involved in aromatic compounds catabolism
IRJ26_RS21200	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IRJ26_RS21205	COG1760	l-serine dehydratase
IRJ26_RS21210	COG1760	l-serine dehydratase
IRJ26_RS21215	COG1461	Dihydroxyacetone kinase
IRJ26_RS21220	COG1302	Protein conserved in bacteria
IRJ26_RS21225	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IRJ26_RS21235	COG1564	THIamine pyrophosphokinase
IRJ26_RS21240	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IRJ26_RS21245	COG1162	GTPase activity
IRJ26_RS21250	COG2815	serine threonine protein kinase
IRJ26_RS21250	COG0515	serine threonine protein kinase
IRJ26_RS21255	COG0631	protein serine/threonine phosphatase activity
IRJ26_RS21260	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IRJ26_RS21265	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IRJ26_RS21265	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IRJ26_RS21270	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IRJ26_RS21275	COG0242	peptide deformylase activity
IRJ26_RS21280	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IRJ26_RS21285	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IRJ26_RS21290	COG1758	RNA polymerase activity
IRJ26_RS21295	COG0194	GDP metabolic process
IRJ26_RS21305	COG1561	YicC-like family, N-terminal region
IRJ26_RS21310	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IRJ26_RS21315	COG1293	RNA-binding protein homologous to eukaryotic snRNP
IRJ26_RS21320	COG1648	precorrin-2 dehydrogenase activity
IRJ26_RS21325	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
IRJ26_RS21330	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IRJ26_RS21335	COG0529	Catalyzes the synthesis of activated sulfate
IRJ26_RS21340	COG2046	Belongs to the sulfate adenylyltransferase family
IRJ26_RS21345	COG0306	phosphate transporter
IRJ26_RS21350	COG0175	sulfate reduction
IRJ26_RS21355	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IRJ26_RS21360	COG0284	orotidine-5'-phosphate decarboxylase activity
IRJ26_RS21365	COG0167	dihydroorotate dehydrogenase activity
IRJ26_RS21370	COG0543	2 iron, 2 sulfur cluster binding
IRJ26_RS21375	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IRJ26_RS21380	COG0505	Belongs to the CarA family
IRJ26_RS21385	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IRJ26_RS21390	COG0540	Belongs to the ATCase OTCase family
IRJ26_RS21395	COG2233	PERMEase
IRJ26_RS21400	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IRJ26_RS21405	COG0564	pseudouridine synthase activity
IRJ26_RS21410	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IRJ26_RS21415	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IRJ26_RS21420	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IRJ26_RS21425	COG3599	regulation of cell shape
IRJ26_RS21430	COG2302	S4 RNA-binding domain
IRJ26_RS21435	COG0762	integral membrane protein
IRJ26_RS21440	COG1799	cell septum assembly
IRJ26_RS21445	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IRJ26_RS21450	COG1496	oxidoreductase activity
IRJ26_RS21455	COG1873	PFAM PRC-barrel domain
IRJ26_RS21460	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IRJ26_RS21465	COG1119	ATPase activity
IRJ26_RS21470	COG1191	sigma factor activity
IRJ26_RS21475	COG1191	sigma factor activity
IRJ26_RS21485	COG1404	Belongs to the peptidase S8 family
IRJ26_RS21485	COG4412	M6 family metalloprotease domain protein
IRJ26_RS21490	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IRJ26_RS21495	COG0849	cell division
IRJ26_RS21500	COG3856	small basic protein
IRJ26_RS21505	COG3879	Bacterial protein of unknown function (DUF881)
IRJ26_RS21510	COG3879	Bacterial protein of unknown function (DUF881)
IRJ26_RS21515	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IRJ26_RS21520	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IRJ26_RS21525	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IRJ26_RS21530	COG0772	Belongs to the SEDS family
IRJ26_RS21535	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IRJ26_RS21540	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IRJ26_RS21545	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IRJ26_RS21550	COG0768	penicillin binding
IRJ26_RS21560	COG0768	penicillin binding
IRJ26_RS21565	COG4839	cell division protein FtsL
IRJ26_RS21570	COG0275	rRNA processing
IRJ26_RS21575	COG2001	Belongs to the MraZ family
IRJ26_RS21580	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
IRJ26_RS21585	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IRJ26_RS21590	COG0454	-acetyltransferase
IRJ26_RS21605	COG1399	metal-binding, possibly nucleic acid-binding protein
IRJ26_RS21615	COG1323	Belongs to the UPF0348 family
IRJ26_RS21620	COG3480	Lon protease (S16) C-terminal proteolytic domain
IRJ26_RS21625	COG1752	Esterase of the alpha-beta hydrolase superfamily
IRJ26_RS21630	COG3314	Sporulation integral membrane protein YlbJ
IRJ26_RS21635	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IRJ26_RS21640	COG0742	ribosomal rna small subunit methyltransferase
IRJ26_RS21645	COG4471	UPF0298 protein
IRJ26_RS21650	COG3679	Belongs to the UPF0342 family
IRJ26_RS21665	COG2340	Cysteine-rich secretory protein family
IRJ26_RS21670	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
IRJ26_RS21680	COG3336	cytochrome c oxidase
IRJ26_RS21685	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IRJ26_RS21690	COG1845	cytochrome c oxidase, subunit III
IRJ26_RS21695	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IRJ26_RS21700	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IRJ26_RS21700	COG2010	Cytochrome c
IRJ26_RS21705	COG0109	protoheme IX farnesyltransferase activity
IRJ26_RS21710	COG1612	heme a metabolic process
IRJ26_RS21715	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IRJ26_RS21720	COG0772	Belongs to the SEDS family
IRJ26_RS21725	COG4838	Belongs to the UPF0358 family
IRJ26_RS21730	COG2066	Belongs to the glutaminase family
IRJ26_RS21735	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IRJ26_RS21740	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IRJ26_RS21750	COG4896	Protein conserved in bacteria
IRJ26_RS21760	COG1217	gtp-binding protein TYPA
IRJ26_RS21780	COG1595	DNA-templated transcription, initiation
IRJ26_RS21800	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IRJ26_RS21810	COG0483	inositol monophosphate 1-phosphatase activity
IRJ26_RS21820	COG4493	Belongs to the UPF0637 family
IRJ26_RS21825	COG4476	Belongs to the UPF0223 family
IRJ26_RS21830	COG1982	Orn Lys Arg decarboxylase major
IRJ26_RS21840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IRJ26_RS21845	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IRJ26_RS21850	COG0508	dehydrogenase complex catalyzes the overall conversion of
IRJ26_RS21855	COG0022	dehydrogenase e1 component
IRJ26_RS21860	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IRJ26_RS21865	COG0497	DNA recombination
IRJ26_RS21875	COG0242	peptide deformylase activity
IRJ26_RS21880	COG0561	phosphatase activity
IRJ26_RS21885	COG5503	Protein of unknown function (DUF1447)
IRJ26_RS21890	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IRJ26_RS21895	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IRJ26_RS21900	COG0569	domain protein
IRJ26_RS21905	COG2105	PFAM AIG2 family protein
IRJ26_RS21905	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
IRJ26_RS21910	COG3852	Histidine kinase
IRJ26_RS21915	COG2002	toxin-antitoxin pair type II binding
IRJ26_RS21920	COG1077	Cell shape determining protein MreB Mrl
IRJ26_RS21930	COG2309	aminopeptidase activity
IRJ26_RS21935	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IRJ26_RS21940	COG0488	(ABC) transporter
IRJ26_RS21950	COG0681	Belongs to the peptidase S26 family
IRJ26_RS21955	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IRJ26_RS21955	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IRJ26_RS21955	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IRJ26_RS21960	COG1105	Belongs to the carbohydrate kinase PfkB family
IRJ26_RS21965	COG1349	DNA-binding transcription factor activity
IRJ26_RS21970	COG0577	efflux transmembrane transporter activity
IRJ26_RS21975	COG1136	(ABC) transporter
IRJ26_RS21980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IRJ26_RS21990	COG1132	(ABC) transporter
IRJ26_RS21995	COG1132	(ABC) transporter
IRJ26_RS22000	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IRJ26_RS22005	COG0314	molybdopterin synthase activity
IRJ26_RS22010	COG1763	Mo-molybdopterin cofactor biosynthetic process
IRJ26_RS22015	COG0303	'Molybdopterin
IRJ26_RS22020	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IRJ26_RS22025	COG0746	molybdenum cofactor guanylyltransferase activity
IRJ26_RS22040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IRJ26_RS22045	COG0450	alkyl hydroperoxide reductase
IRJ26_RS22050	COG0668	transmembrane transport
IRJ26_RS22060	COG1473	amidohydrolase
IRJ26_RS22065	COG2171	N-acyltransferase activity
IRJ26_RS22070	COG0716	FMN binding
IRJ26_RS22080	COG0716	FMN binding
IRJ26_RS22085	COG0583	DNA-binding transcription factor activity
IRJ26_RS22090	COG0517	IMP dehydrogenase activity
IRJ26_RS22100	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
IRJ26_RS22105	COG4703	Protein of unknown function (DUF1797)
IRJ26_RS22110	COG2200	EAL domain
IRJ26_RS22120	COG3409	Peptidoglycan-binding domain 1 protein
IRJ26_RS22125	COG3409	Peptidoglycan-binding domain 1 protein
IRJ26_RS22130	COG1028	Short-chain dehydrogenase reductase Sdr
IRJ26_RS22135	COG1408	metallophosphoesterase
IRJ26_RS22140	COG1376	ErfK ybiS ycfS ynhG family protein
IRJ26_RS22145	COG2814	Major facilitator Superfamily
IRJ26_RS22155	COG0784	Response regulator, receiver
IRJ26_RS22155	COG0835	chemotaxis
IRJ26_RS22165	COG0436	Aminotransferase