locus-tag	class	description
GII86_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GII86_RS00010	COG0592	DNA-directed DNA polymerase activity
GII86_RS00015	COG2501	S4 domain
GII86_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GII86_RS00030	COG0187	DNA topoisomerase II activity
GII86_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GII86_RS00070	COG0516	GMP reductase activity
GII86_RS00070	COG0517	IMP dehydrogenase activity
GII86_RS00075	COG1686	Belongs to the peptidase S11 family
GII86_RS00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GII86_RS00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GII86_RS00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GII86_RS00100	COG1428	Deoxynucleoside kinase
GII86_RS00105	COG1428	Deoxynucleoside kinase
GII86_RS00110	COG3858	chitin binding
GII86_RS00110	COG1388	LysM domain
GII86_RS00115	COG1335	isochorismatase
GII86_RS00120	COG0590	tRNA wobble adenosine to inosine editing
GII86_RS00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GII86_RS00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GII86_RS00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GII86_RS00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
GII86_RS00190	COG3853	Toxic anion resistance protein (TelA)
GII86_RS00195	COG1982	Orn Lys Arg decarboxylase major
GII86_RS00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GII86_RS00205	COG3870	Protein conserved in bacteria
GII86_RS00210	COG1728	Protein conserved in bacteria
GII86_RS00215	COG0470	DNA polymerase III
GII86_RS00220	COG1774	PSP1 C-terminal conserved region
GII86_RS00225	COG4467	Involved in initiation control of chromosome replication
GII86_RS00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GII86_RS00235	COG2827	Endonuclease containing a URI domain
GII86_RS00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GII86_RS00245	COG2002	toxin-antitoxin pair type II binding
GII86_RS00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII86_RS00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII86_RS00255	COG0084	hydrolase, TatD family'
GII86_RS00260	COG3583	domain protein
GII86_RS00260	COG3584	3D domain protein
GII86_RS00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GII86_RS00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GII86_RS00280	COG4466	Protein conserved in bacteria
GII86_RS00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GII86_RS00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GII86_RS00300	COG0251	oxidation-reduction process
GII86_RS00305	COG2088	sporulation resulting in formation of a cellular spore
GII86_RS00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GII86_RS00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GII86_RS00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GII86_RS00325	COG0193	aminoacyl-tRNA hydrolase activity
GII86_RS00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GII86_RS00340	COG2002	toxin-antitoxin pair type II binding
GII86_RS00345	COG2244	polysaccharide biosynthetic process
GII86_RS00350	COG3956	TIGRFAM MazG family protein
GII86_RS00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GII86_RS00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GII86_RS00375	COG1098	S1 RNA binding domain
GII86_RS00390	COG2208	phosphoserine phosphatase activity
GII86_RS00395	COG2304	oxidoreductase activity
GII86_RS00400	COG0515	serine threonine protein kinase
GII86_RS00405	COG0037	tRNA processing
GII86_RS00410	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GII86_RS00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GII86_RS00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GII86_RS00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GII86_RS00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GII86_RS00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GII86_RS00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GII86_RS00445	COG0512	Glutamine amidotransferase of anthranilate synthase
GII86_RS00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII86_RS00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GII86_RS00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GII86_RS00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GII86_RS00470	COG1396	sequence-specific DNA binding
GII86_RS00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GII86_RS00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GII86_RS00560	COG4463	regulation of RNA biosynthetic process
GII86_RS00565	COG3880	PFAM UvrB UvrC protein
GII86_RS00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
GII86_RS00575	COG0542	response to heat
GII86_RS00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GII86_RS00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
GII86_RS00590	COG4956	integral membrane protein (PIN domain superfamily)
GII86_RS00595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GII86_RS00600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GII86_RS00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GII86_RS00610	COG1045	serine acetyltransferase
GII86_RS00615	COG0215	cysteine-tRNA ligase activity
GII86_RS00620	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GII86_RS00625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GII86_RS00630	COG3688	RNA-binding protein containing a PIN domain
GII86_RS00635	COG1595	DNA-templated transcription, initiation
GII86_RS00645	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GII86_RS00650	COG0250	Participates in transcription elongation, termination and antitermination
GII86_RS00660	COG0081	regulation of translation
GII86_RS00665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GII86_RS00675	COG2813	Specifically methylates the guanine in position
GII86_RS00680	COG0085	RNA polymerase activity
GII86_RS00685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GII86_RS00690	COG1358	cellular component organization or biogenesis
GII86_RS00695	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GII86_RS00700	COG0049	tRNA binding
GII86_RS00705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GII86_RS00710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GII86_RS00715	COG0596	Alpha beta hydrolase
GII86_RS00725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GII86_RS00730	COG0088	Forms part of the polypeptide exit tunnel
GII86_RS00740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GII86_RS00755	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GII86_RS00760	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GII86_RS00770	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GII86_RS00775	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GII86_RS00785	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GII86_RS00795	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GII86_RS00800	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GII86_RS00805	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GII86_RS00810	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GII86_RS00820	COG0200	Binds to the 23S rRNA
GII86_RS00825	COG0201	protein transport
GII86_RS00830	COG0563	adenylate kinase activity
GII86_RS00835	COG0024	Methionine aminopeptidase
GII86_RS00840	COG2163	COG2163 Ribosomal protein L14E L6E L27E
GII86_RS00850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GII86_RS00855	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GII86_RS00860	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GII86_RS00865	COG0202	RNA polymerase activity
GII86_RS00870	COG0203	ribosomal protein L17
GII86_RS00875	COG1122	ATPase activity
GII86_RS00880	COG1122	ATPase activity
GII86_RS00885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GII86_RS00890	COG0101	tRNA pseudouridine synthase activity
GII86_RS00895	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GII86_RS00900	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GII86_RS00905	COG0582	viral genome integration into host DNA
GII86_RS01075	COG3953	SLT domain
GII86_RS01075	COG5412	phage tail tape measure protein
GII86_RS01110	COG4824	toxin secretion phage lysis holin
GII86_RS01115	COG1388	LysM domain
GII86_RS01115	COG3409	Peptidoglycan-binding domain 1 protein
GII86_RS01115	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII86_RS01135	COG2226	methyltransferase
GII86_RS01145	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII86_RS01150	COG0489	protein tyrosine kinase activity
GII86_RS01160	COG2194	sulfuric ester hydrolase activity
GII86_RS01165	COG0726	polysaccharide deacetylase
GII86_RS01245	COG0659	secondary active sulfate transmembrane transporter activity
GII86_RS01250	COG0385	Bile acid
GII86_RS01255	COG2819	hydrolase of the alpha beta superfamily
GII86_RS01260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII86_RS01265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII86_RS01270	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII86_RS01275	COG2207	Transcriptional regulator
GII86_RS01275	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII86_RS01280	COG3876	Protein conserved in bacteria
GII86_RS01285	COG1472	Belongs to the glycosyl hydrolase 3 family
GII86_RS01290	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GII86_RS01295	COG1263	PTS System
GII86_RS01295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII86_RS01300	COG1737	Transcriptional regulator
GII86_RS01305	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GII86_RS01310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII86_RS01315	COG1683	Conserved Protein
GII86_RS01345	COG1595	DNA-templated transcription, initiation
GII86_RS01350	COG5662	AntiSigma factor
GII86_RS01355	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GII86_RS01360	COG4856	YbbR-like protein
GII86_RS01365	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GII86_RS01375	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GII86_RS01385	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GII86_RS01390	COG2169	Transcriptional regulator
GII86_RS01395	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GII86_RS01400	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GII86_RS01405	COG3002	Belongs to the UPF0753 family
GII86_RS01410	COG0288	reversible hydration of carbon dioxide
GII86_RS01420	COG5609	conserved protein (DUF2294)
GII86_RS01425	COG0640	Transcriptional regulator
GII86_RS01430	COG2814	Major facilitator Superfamily
GII86_RS01445	COG0515	serine threonine protein kinase
GII86_RS01460	COG1113	amino acid transport
GII86_RS01480	COG2124	cytochrome p450
GII86_RS01490	COG0531	amino acid
GII86_RS01495	COG0584	glycerophosphoryl diester phosphodiesterase
GII86_RS01500	COG2271	Major facilitator Superfamily
GII86_RS01510	COG0456	acetyltransferase
GII86_RS01510	COG1846	Transcriptional regulator
GII86_RS01515	COG2271	Major facilitator Superfamily
GII86_RS01520	COG0697	spore germination
GII86_RS01525	COG2207	Transcriptional regulator
GII86_RS01525	COG1917	Cupin 2, conserved barrel domain protein
GII86_RS01550	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GII86_RS01555	COG3591	Belongs to the peptidase S1B family
GII86_RS01565	COG0596	Alpha beta hydrolase
GII86_RS01570	COG1183	phosphatidylcholine synthase activity
GII86_RS01575	COG0586	Pfam SNARE associated Golgi protein
GII86_RS01580	COG0688	phosphatidylethanolamine metabolic process
GII86_RS01590	COG2312	Erythromycin esterase
GII86_RS01595	COG2207	Transcriptional regulator
GII86_RS01600	COG1054	Belongs to the UPF0176 family
GII86_RS01605	COG1301	dicarboxylic acid transport
GII86_RS01610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII86_RS01610	COG1263	PTS System
GII86_RS01610	COG2190	(PTS) system
GII86_RS01615	COG0363	glucosamine-6-phosphate deaminase activity
GII86_RS01620	COG2188	Transcriptional regulator
GII86_RS01630	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII86_RS01635	COG0833	amino acid
GII86_RS01640	COG2040	homocysteine
GII86_RS01650	COG1115	amino acid carrier protein
GII86_RS01655	COG2066	Belongs to the glutaminase family
GII86_RS01660	COG4191	Histidine kinase
GII86_RS01665	COG0784	Response regulator, receiver
GII86_RS01670	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GII86_RS01675	COG1012	belongs to the aldehyde dehydrogenase family
GII86_RS01680	COG2271	Major facilitator Superfamily
GII86_RS01685	COG4948	Mandelate Racemase Muconate Lactonizing
GII86_RS01690	COG2186	Transcriptional regulator
GII86_RS01695	COG2721	sulfolactate sulfo-lyase activity
GII86_RS01700	COG3173	Aminoglycoside phosphotransferase
GII86_RS01710	COG0697	spore germination
GII86_RS01715	COG0745	RESPONSE REGULATOR receiver
GII86_RS01720	COG2205	protein histidine kinase activity
GII86_RS01725	COG1131	(ABC) transporter
GII86_RS01745	COG3773	Cell wall hydrolase
GII86_RS01750	COG2304	oxidoreductase activity
GII86_RS01760	COG3540	Alkaline phosphatase
GII86_RS01765	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GII86_RS01770	COG0805	protein transport
GII86_RS01775	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GII86_RS01780	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GII86_RS01785	COG0477	Major facilitator Superfamily
GII86_RS01790	COG1309	transcriptional regulator
GII86_RS01795	COG0252	asparaginase activity
GII86_RS01800	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GII86_RS01805	COG1714	RDD family
GII86_RS01810	COG1405	negative regulation of cell septum assembly
GII86_RS01810	COG3012	SEC-C Motif Domain Protein
GII86_RS01815	COG3290	protein histidine kinase activity
GII86_RS01820	COG3279	Response regulator of the LytR AlgR family
GII86_RS01825	COG4555	ABC transporter
GII86_RS01830	COG1668	transmembrane transport
GII86_RS01835	COG0667	Aldo Keto reductase
GII86_RS01850	COG1595	DNA-templated transcription, initiation
GII86_RS01855	COG1595	DNA-templated transcription, initiation
GII86_RS01860	COG1876	peptidase activity
GII86_RS01865	COG0457	Tetratricopeptide repeat
GII86_RS01870	COG1028	Short-chain dehydrogenase reductase Sdr
GII86_RS01875	COG0366	Alpha amylase catalytic
GII86_RS01880	COG0803	Belongs to the bacterial solute-binding protein 9 family
GII86_RS01885	COG1121	(ABC) transporter
GII86_RS01890	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GII86_RS01895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII86_RS01900	COG2310	stress, protein
GII86_RS01905	COG2310	stress, protein
GII86_RS01910	COG2310	stress, protein
GII86_RS01915	COG0861	Integral membrane protein TerC family
GII86_RS01925	COG3853	Toxic anion resistance protein (TelA)
GII86_RS01930	COG0477	Major facilitator Superfamily
GII86_RS01935	COG2814	Major facilitator Superfamily
GII86_RS01940	COG0640	Transcriptional regulator
GII86_RS01945	COG0517	IMP dehydrogenase activity
GII86_RS01945	COG4175	Glycine betaine
GII86_RS01950	COG4176	ABC-type proline glycine betaine transport system permease component
GII86_RS01955	COG2113	Glycine betaine
GII86_RS01960	COG1473	amidohydrolase
GII86_RS01965	COG1288	antiporter activity
GII86_RS01975	COG0366	Alpha amylase catalytic
GII86_RS01980	COG0039	L-malate dehydrogenase activity
GII86_RS01985	COG1620	l-lactate permease
GII86_RS01990	COG2814	Major facilitator Superfamily
GII86_RS01995	COG1846	Transcriptional regulator
GII86_RS02000	COG1280	lysine exporter protein (LysE YggA)
GII86_RS02005	COG3403	YqcI/YcgG family
GII86_RS02010	COG1113	amino acid transport
GII86_RS02015	COG3665	Urea carboxylase-associated protein
GII86_RS02020	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GII86_RS02025	COG1660	Displays ATPase and GTPase activities
GII86_RS02030	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GII86_RS02035	COG2226	methyltransferase
GII86_RS02040	COG0583	DNA-binding transcription factor activity
GII86_RS02045	COG3458	cephalosporin-C deacetylase activity
GII86_RS02050	COG3541	Predicted nucleotidyltransferase
GII86_RS02055	COG0506	proline dehydrogenase activity
GII86_RS02060	COG1012	belongs to the aldehyde dehydrogenase family
GII86_RS02065	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII86_RS02070	COG2508	Transcriptional regulator
GII86_RS02075	COG3689	TIGRFAM TIGR03943 family protein
GII86_RS02080	COG0701	Predicted permease
GII86_RS02085	COG2267	carboxylic ester hydrolase activity
GII86_RS02090	COG0492	ferredoxin-NADP+ reductase activity
GII86_RS02095	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GII86_RS02095	COG1587	Uroporphyrinogen-III synthase
GII86_RS02100	COG2146	nitrite reductase [NAD(P)H] activity
GII86_RS02105	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GII86_RS02110	COG0243	molybdopterin cofactor binding
GII86_RS02115	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GII86_RS02120	COG2223	nitrite transmembrane transporter activity
GII86_RS02125	COG1469	GTP cyclohydrolase I activity
GII86_RS02130	COG1376	ErfK ybiS ycfS ynhG family protein
GII86_RS02140	COG0523	cobalamin synthesis protein
GII86_RS02145	COG0765	amino acid transport
GII86_RS02150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII86_RS02170	COG1846	Transcriptional regulator
GII86_RS02180	COG3842	ATPase activity
GII86_RS02185	COG2723	6-phospho-beta-galactosidase activity
GII86_RS02195	COG3209	COG3209 Rhs family protein
GII86_RS02200	COG3290	protein histidine kinase activity
GII86_RS02200	COG0840	transmembrane signaling receptor activity
GII86_RS02205	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GII86_RS02210	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
GII86_RS02215	COG1733	regulation of RNA biosynthetic process
GII86_RS02220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII86_RS02225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII86_RS02230	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII86_RS02235	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
GII86_RS02240	COG2814	Major facilitator Superfamily
GII86_RS02250	COG0697	spore germination
GII86_RS02255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII86_RS02265	COG2364	Membrane
GII86_RS02270	COG1126	abc transporter atp-binding protein
GII86_RS02275	COG0765	amino acid transport
GII86_RS02280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII86_RS02285	COG0583	DNA-binding transcription factor activity
GII86_RS02290	COG0163	prenyltransferase activity
GII86_RS02295	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GII86_RS02310	COG0596	Alpha beta hydrolase
GII86_RS02315	COG3104	oligopeptide transport
GII86_RS02320	COG5434	Belongs to the glycosyl hydrolase 28 family
GII86_RS02330	COG0697	spore germination
GII86_RS02340	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GII86_RS02345	COG1136	(ABC) transporter
GII86_RS02350	COG0577	efflux transmembrane transporter activity
GII86_RS02355	COG0745	RESPONSE REGULATOR receiver
GII86_RS02360	COG5002	protein histidine kinase activity
GII86_RS02360	COG3850	Histidine kinase
GII86_RS02365	COG0457	Tetratricopeptide repeat
GII86_RS02385	COG0527	aspartate kinase activity
GII86_RS02390	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII86_RS02395	COG4605	iron ion homeostasis
GII86_RS02400	COG4604	ABC transporter, ATP-binding protein
GII86_RS02405	COG4607	ABC-type enterochelin transport system periplasmic component
GII86_RS02410	COG2814	Major facilitator Superfamily
GII86_RS02415	COG1309	transcriptional regulator
GII86_RS02420	COG0778	Nitroreductase
GII86_RS02425	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GII86_RS02430	COG0640	Transcriptional regulator
GII86_RS02435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII86_RS02440	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GII86_RS02445	COG1012	belongs to the aldehyde dehydrogenase family
GII86_RS02450	COG4975	Glucose uptake
GII86_RS02455	COG1028	Short-chain dehydrogenase reductase Sdr
GII86_RS02460	COG4549	nuclear export factor GLE1
GII86_RS02465	COG2372	response to copper ion
GII86_RS02465	COG1276	copper resistance
GII86_RS02470	COG1349	DNA-binding transcription factor activity
GII86_RS02480	COG2213	PTS system mannitol-specific
GII86_RS02485	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII86_RS02490	COG0246	Mannitol dehydrogenase
GII86_RS02495	COG0473	3-isopropylmalate dehydrogenase activity
GII86_RS02500	COG0681	Belongs to the peptidase S26 family
GII86_RS02510	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GII86_RS02520	COG0561	phosphatase activity
GII86_RS02525	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GII86_RS02530	COG1914	H( )-stimulated, divalent metal cation uptake system
GII86_RS02535	COG4336	lyase activity
GII86_RS02540	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GII86_RS02545	COG1984	allophanate hydrolase subunit 2
GII86_RS02550	COG1414	Transcriptional regulator
GII86_RS02555	COG2755	lipolytic protein G-D-S-L family
GII86_RS02565	COG2329	Antibiotic biosynthesis monooxygenase
GII86_RS02570	COG0768	penicillin binding
GII86_RS02575	COG4989	oxidoreductase activity
GII86_RS02580	COG3711	transcriptional antiterminator
GII86_RS02585	COG0318	PFAM AMP-dependent synthetase and ligase
GII86_RS02590	COG2226	methyltransferase
GII86_RS02595	COG1028	Short-chain dehydrogenase reductase Sdr
GII86_RS02600	COG1917	Cupin 2, conserved barrel domain protein
GII86_RS02605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII86_RS02610	COG3871	stress protein (general stress protein 26)
GII86_RS02620	COG2814	Major facilitator Superfamily
GII86_RS02625	COG1522	sequence-specific DNA binding
GII86_RS02630	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GII86_RS02630	COG0551	DNA topoisomerase type I activity
GII86_RS02635	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GII86_RS02640	COG3706	GGDEF domain
GII86_RS02645	COG5298	Protein conserved in bacteria
GII86_RS02650	COG1215	transferase activity, transferring glycosyl groups
GII86_RS02660	COG0531	amino acid
GII86_RS02665	COG0494	nUDIX hydrolase
GII86_RS02670	COG0028	Belongs to the TPP enzyme family
GII86_RS02695	COG1914	H( )-stimulated, divalent metal cation uptake system
GII86_RS02700	COG2261	transglycosylase associated protein
GII86_RS02705	COG4876	unkown
GII86_RS02710	COG2217	Heavy metal translocating P-type atpase
GII86_RS02715	COG3729	General stress protein
GII86_RS02720	COG0662	Cupin 2, conserved barrel domain protein
GII86_RS02725	COG2329	Antibiotic biosynthesis monooxygenase
GII86_RS02730	COG3546	catalase activity
GII86_RS02735	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GII86_RS02740	COG3290	protein histidine kinase activity
GII86_RS02745	COG4565	transcriptional regulatory protein
GII86_RS02750	COG1301	dicarboxylic acid transport
GII86_RS02755	COG0628	permease
GII86_RS02760	COG1131	(ABC) transporter
GII86_RS02765	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GII86_RS02775	COG1960	acyl-CoA dehydrogenase activity
GII86_RS02790	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GII86_RS02795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII86_RS02800	COG1181	Belongs to the D-alanine--D-alanine ligase family
GII86_RS02805	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GII86_RS02810	COG0513	Belongs to the DEAD box helicase family
GII86_RS02815	COG3402	PFAM membrane-flanked domain
GII86_RS02820	COG3428	Bacterial PH domain
GII86_RS02825	COG0705	Rhomboid family
GII86_RS02830	COG0736	holo-[acyl-carrier-protein] synthase activity
GII86_RS02835	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GII86_RS02840	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GII86_RS02845	COG0864	Transcriptional regulator
GII86_RS02850	COG2337	Toxic component of a toxin-antitoxin (TA) module
GII86_RS02855	COG1366	Belongs to the anti-sigma-factor antagonist family
GII86_RS02860	COG1366	Belongs to the anti-sigma-factor antagonist family
GII86_RS02865	COG2172	sigma factor antagonist activity
GII86_RS02870	COG2208	phosphoserine phosphatase activity
GII86_RS02875	COG1366	Belongs to the anti-sigma-factor antagonist family
GII86_RS02880	COG2172	sigma factor antagonist activity
GII86_RS02885	COG1191	sigma factor activity
GII86_RS02890	COG2208	phosphoserine phosphatase activity
GII86_RS02895	COG2183	response to ionizing radiation
GII86_RS02905	COG3091	SprT-like family
GII86_RS02950	COG0583	DNA-binding transcription factor activity
GII86_RS02955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII86_RS02965	COG5444	nuclease activity
GII86_RS02975	COG1476	TRANSCRIPTIONal
GII86_RS02995	COG0693	protein deglycase activity
GII86_RS03000	COG1278	Cold shock
GII86_RS03005	COG1329	Transcriptional regulator
GII86_RS03010	COG0697	spore germination
GII86_RS03015	COG2207	Transcriptional regulator
GII86_RS03015	COG1917	Cupin 2, conserved barrel domain protein
GII86_RS03020	COG0697	spore germination
GII86_RS03025	COG3708	Transcriptional regulator
GII86_RS03025	COG2207	Transcriptional regulator
GII86_RS03030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII86_RS03035	COG0477	Major facilitator Superfamily
GII86_RS03045	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
GII86_RS03065	COG1309	transcriptional regulator
GII86_RS03070	COG0697	spore germination
GII86_RS03075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII86_RS03080	COG2030	dehydratase
GII86_RS03085	COG3545	Serine hydrolase
GII86_RS03090	COG1733	regulation of RNA biosynthetic process
GII86_RS03095	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII86_RS03100	COG1733	regulation of RNA biosynthetic process
GII86_RS03105	COG2249	NAD(P)H dehydrogenase (quinone) activity
GII86_RS03110	COG2814	Major facilitator Superfamily
GII86_RS03115	COG1309	transcriptional regulator
GII86_RS03120	COG0640	Transcriptional regulator
GII86_RS03125	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GII86_RS03135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII86_RS03140	COG0697	spore germination
GII86_RS03145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII86_RS03150	COG0076	glutamate decarboxylase activity
GII86_RS03155	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GII86_RS03160	COG0640	Transcriptional regulator
GII86_RS03165	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GII86_RS03180	COG4585	Histidine kinase
GII86_RS03185	COG2197	response regulator
GII86_RS03190	COG2409	Drug exporters of the RND superfamily
GII86_RS03195	COG1811	Na channel or pump
GII86_RS03200	COG4978	Transcriptional regulator
GII86_RS03200	COG0789	Transcriptional regulator
GII86_RS03205	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GII86_RS03210	COG0778	Nitroreductase
GII86_RS03215	COG0346	lactoylglutathione lyase activity
GII86_RS03220	COG2259	Doxx family
GII86_RS03225	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII86_RS03245	COG2323	membrane
GII86_RS03250	COG0071	Belongs to the small heat shock protein (HSP20) family
GII86_RS03265	COG1309	transcriptional regulator
GII86_RS03275	COG0456	acetyltransferase
GII86_RS03280	COG0488	(ABC) transporter
GII86_RS03285	COG1113	amino acid transport
GII86_RS03290	COG2318	DinB family
GII86_RS03295	COG1846	Transcriptional regulator
GII86_RS03300	COG2409	Drug exporters of the RND superfamily
GII86_RS03300	COG1033	growth of symbiont in host cell
GII86_RS03305	COG0778	Nitroreductase
GII86_RS03310	COG1846	Transcriptional regulator
GII86_RS03315	COG2814	Major facilitator Superfamily
GII86_RS03320	COG0730	response to heat
GII86_RS03325	COG1802	Transcriptional regulator
GII86_RS03330	COG1388	LysM domain
GII86_RS03330	COG3858	chitin binding
GII86_RS03335	COG1819	glycosyl
GII86_RS03345	COG1785	Belongs to the alkaline phosphatase family
GII86_RS03350	COG5646	InterPro IPR014922
GII86_RS03360	COG0454	-acetyltransferase
GII86_RS03365	COG1078	dGTPase activity
GII86_RS03370	COG1388	LysM domain
GII86_RS03375	COG2814	Major facilitator Superfamily
GII86_RS03380	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII86_RS03385	COG1447	Phosphotransferase system cellobiose-specific component IIA
GII86_RS03390	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII86_RS03395	COG2723	6-phospho-beta-galactosidase activity
GII86_RS03400	COG2188	Transcriptional regulator
GII86_RS03405	COG1940	carbohydrate kinase activity
GII86_RS03410	COG1482	cell wall glycoprotein biosynthetic process
GII86_RS03415	COG4124	Belongs to the glycosyl hydrolase 26 family
GII86_RS03460	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GII86_RS03465	COG0802	atpase or kinase
GII86_RS03470	COG1214	PFAM Peptidase M22, glycoprotease
GII86_RS03475	COG0456	acetyltransferase
GII86_RS03480	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GII86_RS03485	COG0488	(ABC) transporter
GII86_RS03490	COG0315	cyclic pyranopterin monophosphate synthase activity
GII86_RS03495	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GII86_RS03500	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GII86_RS03505	COG0805	protein transport
GII86_RS03515	COG1266	CAAX protease self-immunity
GII86_RS03525	COG0459	protein refolding
GII86_RS03535	COG1073	alpha beta
GII86_RS03545	COG1063	alcohol dehydrogenase
GII86_RS03550	COG2211	Major facilitator Superfamily
GII86_RS03555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII86_RS03560	COG1842	Phage shock protein A
GII86_RS03565	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GII86_RS03570	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GII86_RS03575	COG4260	virion core protein, lumpy skin disease virus
GII86_RS03585	COG2814	Major facilitator Superfamily
GII86_RS03590	COG1063	alcohol dehydrogenase
GII86_RS03595	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GII86_RS03600	COG0823	Involved in the tonB-independent uptake of proteins
GII86_RS03615	COG2267	carboxylic ester hydrolase activity
GII86_RS03625	COG2132	Multicopper oxidase
GII86_RS03630	COG1113	amino acid transport
GII86_RS03640	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GII86_RS03645	COG0714	Associated with various cellular activities
GII86_RS03650	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
GII86_RS03655	COG1305	Transglutaminase-like
GII86_RS03660	COG0519	Catalyzes the synthesis of GMP from XMP
GII86_RS03660	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GII86_RS03675	COG2252	PERMEase
GII86_RS03680	COG3064	Membrane
GII86_RS03690	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
GII86_RS03700	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GII86_RS03705	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GII86_RS03710	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GII86_RS03715	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GII86_RS03720	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GII86_RS03725	COG0047	phosphoribosylformylglycinamidine synthase activity
GII86_RS03730	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GII86_RS03735	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GII86_RS03740	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GII86_RS03745	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GII86_RS03750	COG0138	bifunctional purine biosynthesis protein purh
GII86_RS03755	COG0151	Belongs to the GarS family
GII86_RS03760	COG1522	sequence-specific DNA binding
GII86_RS03765	COG0531	amino acid
GII86_RS03775	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GII86_RS03780	COG1470	cell adhesion involved in biofilm formation
GII86_RS03785	COG4496	protein, YerC YecD
GII86_RS03790	COG0069	glutamate synthase activity
GII86_RS03795	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
GII86_RS03800	COG0210	DNA helicase
GII86_RS03805	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GII86_RS03810	COG4851	CamS sex pheromone cAM373 precursor
GII86_RS03815	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII86_RS03820	COG1285	pathogenesis
GII86_RS03825	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII86_RS03830	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GII86_RS03835	COG0154	amidase activity
GII86_RS03840	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GII86_RS03845	COG1309	transcriptional regulator
GII86_RS03850	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GII86_RS03855	COG1597	lipid kinase activity
GII86_RS03860	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GII86_RS03880	COG1401	restriction endodeoxyribonuclease activity
GII86_RS03940	COG3586	endonuclease activity
GII86_RS03945	COG3391	amine dehydrogenase activity
GII86_RS03950	COG0457	Tetratricopeptide repeat
GII86_RS03960	COG0217	transcriptional regulatory protein
GII86_RS03970	COG1309	transcriptional regulator
GII86_RS03975	COG3631	Ketosteroid isomerase-related protein
GII86_RS03980	COG0702	epimerase
GII86_RS03995	COG3546	catalase activity
GII86_RS04000	COG0454	-acetyltransferase
GII86_RS04010	COG5578	integral membrane protein
GII86_RS04015	COG2972	Histidine kinase
GII86_RS04020	COG4753	response regulator
GII86_RS04020	COG2207	Transcriptional regulator
GII86_RS04025	COG1653	transport
GII86_RS04030	COG1175	transmembrane transport
GII86_RS04035	COG0395	ABC-type sugar transport system, permease component
GII86_RS04040	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GII86_RS04045	COG2207	Transcriptional regulator
GII86_RS04050	COG2755	lipolytic protein G-D-S-L family
GII86_RS04060	COG5578	integral membrane protein
GII86_RS04065	COG3401	FG-GAP repeat protein
GII86_RS04070	COG3401	FG-GAP repeat protein
GII86_RS04075	COG2755	lipolytic protein G-D-S-L family
GII86_RS04090	COG1653	transport
GII86_RS04095	COG4209	transmembrane transport
GII86_RS04100	COG0395	ABC-type sugar transport system, permease component
GII86_RS04105	COG1486	melibiose metabolic process
GII86_RS04110	COG2323	membrane
GII86_RS04115	COG2329	Antibiotic biosynthesis monooxygenase
GII86_RS04120	COG0346	lactoylglutathione lyase activity
GII86_RS04135	COG5583	Uncharacterized small protein (DUF2292)
GII86_RS04140	COG0670	Belongs to the BI1 family
GII86_RS04145	COG0697	spore germination
GII86_RS04150	COG1846	Transcriptional regulator
GII86_RS04155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GII86_RS04165	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GII86_RS04165	COG2124	cytochrome p450
GII86_RS04170	COG1368	sulfuric ester hydrolase activity
GII86_RS04175	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GII86_RS04180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII86_RS04185	COG1442	glycosyl transferase family 8
GII86_RS04190	COG1216	Glycosyl transferase, family 2
GII86_RS04195	COG1442	glycosyl transferase family 8
GII86_RS04200	COG2223	nitrite transmembrane transporter activity
GII86_RS04205	COG1011	Hydrolase
GII86_RS04210	COG0531	amino acid
GII86_RS04215	COG1012	belongs to the aldehyde dehydrogenase family
GII86_RS04220	COG0840	transmembrane signaling receptor activity
GII86_RS04225	COG0488	(ABC) transporter
GII86_RS04235	COG0789	Transcriptional regulator
GII86_RS04240	COG2814	Major facilitator Superfamily
GII86_RS04255	COG0488	(ABC) transporter
GII86_RS04260	COG0513	Belongs to the DEAD box helicase family
GII86_RS04265	COG0456	acetyltransferase
GII86_RS04270	COG2130	NADP-dependent
GII86_RS04275	COG1120	ATPase activity
GII86_RS04280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII86_RS04285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII86_RS04290	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GII86_RS04305	COG3866	Pectate lyase
GII86_RS04310	COG0471	metal ion transport
GII86_RS04315	COG3290	protein histidine kinase activity
GII86_RS04320	COG4565	transcriptional regulatory protein
GII86_RS04325	COG3181	Tripartite tricarboxylate transporter family receptor
GII86_RS04330	COG2851	Citrate transporter
GII86_RS04335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII86_RS04340	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
GII86_RS04345	COG1254	Belongs to the acylphosphatase family
GII86_RS04350	COG2258	MOSC domain
GII86_RS04370	COG0024	Methionine aminopeptidase
GII86_RS04375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII86_RS04375	COG1263	PTS System
GII86_RS04380	COG1368	sulfuric ester hydrolase activity
GII86_RS04395	COG1115	amino acid carrier protein
GII86_RS04400	COG0531	amino acid
GII86_RS04405	COG0697	spore germination
GII86_RS04410	COG0697	spore germination
GII86_RS04415	COG1263	PTS System
GII86_RS04415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII86_RS04420	COG0366	Alpha amylase catalytic
GII86_RS04425	COG2188	Transcriptional regulator
GII86_RS04430	COG0778	Nitroreductase
GII86_RS04435	COG0737	Belongs to the 5'-nucleotidase family
GII86_RS04440	COG0693	protein deglycase activity
GII86_RS04445	COG2814	Major facilitator Superfamily
GII86_RS04450	COG4840	Belongs to the UPF0435 family
GII86_RS04455	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GII86_RS04460	COG4980	gas vesicle protein
GII86_RS04465	COG1295	ribonuclease BN
GII86_RS04470	COG0477	Major facilitator Superfamily
GII86_RS04475	COG0387	Pfam Sodium calcium exchanger
GII86_RS04485	COG0668	transmembrane transport
GII86_RS04490	COG0535	radical SAM domain protein
GII86_RS04500	COG0726	polysaccharide deacetylase
GII86_RS04505	COG2084	Dehydrogenase
GII86_RS04510	COG0598	Magnesium transport protein CorA
GII86_RS04515	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GII86_RS04520	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GII86_RS04530	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GII86_RS04535	COG4637	Psort location Cytoplasmic, score
GII86_RS04545	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GII86_RS04550	COG0022	dehydrogenase e1 component
GII86_RS04555	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII86_RS04560	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GII86_RS04565	COG3284	Transcriptional regulator
GII86_RS04575	COG1742	UPF0060 membrane protein
GII86_RS04595	COG4842	Belongs to the WXG100 family
GII86_RS04600	COG1486	melibiose metabolic process
GII86_RS04605	COG1737	Transcriptional regulator
GII86_RS04610	COG1263	PTS System
GII86_RS04610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII86_RS04615	COG5434	Belongs to the glycosyl hydrolase 28 family
GII86_RS04620	COG1132	(ABC) transporter
GII86_RS04625	COG1132	(ABC) transporter
GII86_RS04630	COG2259	Doxx family
GII86_RS04635	COG2514	catechol 2,3-dioxygenase activity
GII86_RS04640	COG4977	sequence-specific DNA binding
GII86_RS04640	COG1917	Cupin 2, conserved barrel domain protein
GII86_RS04645	COG2814	Major facilitator Superfamily
GII86_RS04650	COG1082	Xylose isomerase domain protein TIM barrel
GII86_RS04655	COG0673	inositol 2-dehydrogenase activity
GII86_RS04660	COG4585	Histidine kinase
GII86_RS04665	COG2197	response regulator
GII86_RS04670	COG1131	(ABC) transporter
GII86_RS04675	COG1511	domain protein
GII86_RS04675	COG0842	Transport permease protein
GII86_RS04680	COG0842	Transport permease protein
GII86_RS04685	COG1695	Transcriptional regulator
GII86_RS04690	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GII86_RS04695	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
GII86_RS04700	COG1309	transcriptional regulator
GII86_RS04705	COG2814	Major facilitator Superfamily
GII86_RS04710	COG2318	DinB family
GII86_RS04715	COG2814	Major facilitator Superfamily
GII86_RS04720	COG1846	Transcriptional regulator
GII86_RS04725	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GII86_RS04725	COG0392	lysyltransferase activity
GII86_RS04730	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII86_RS04740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII86_RS04745	COG0384	phenazine biosynthesis protein PhzF
GII86_RS04750	COG0778	Nitroreductase
GII86_RS04765	COG1090	epimerase
GII86_RS04770	COG2137	regulation of response to DNA damage stimulus
GII86_RS04780	COG2814	Major facilitator Superfamily
GII86_RS04795	COG3103	Sh3 type 3 domain protein
GII86_RS04800	COG5658	integral membrane protein
GII86_RS04805	COG0596	Alpha beta hydrolase
GII86_RS04810	COG0463	Glycosyl transferase, family 2
GII86_RS04815	COG4485	Bacterial membrane protein, YfhO
GII86_RS04820	COG1988	membrane-bound metal-dependent
GII86_RS04825	COG1194	a g-specific adenine glycosylase
GII86_RS04835	COG1028	Short-chain dehydrogenase reductase Sdr
GII86_RS04850	COG3557	Belongs to the UPF0374 family
GII86_RS04855	COG1132	(ABC) transporter
GII86_RS04860	COG4129	membrane
GII86_RS04865	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GII86_RS04870	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GII86_RS04875	COG0735	belongs to the Fur family
GII86_RS04985	COG4326	sporulation control protein
GII86_RS04995	COG5577	PFAM Coat F domain
GII86_RS05000	COG3340	Belongs to the peptidase S51 family
GII86_RS05005	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GII86_RS05015	COG0753	catalase activity
GII86_RS05020	COG1116	anion transmembrane transporter activity
GII86_RS05025	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GII86_RS05030	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GII86_RS05035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII86_RS05045	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GII86_RS05055	COG1476	TRANSCRIPTIONal
GII86_RS05065	COG3382	B3 4 domain protein
GII86_RS05070	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GII86_RS05080	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GII86_RS05085	COG0789	Transcriptional regulator
GII86_RS05090	COG1664	Polymer-forming cytoskeletal
GII86_RS05095	COG1664	Polymer-forming cytoskeletal
GII86_RS05100	COG2766	serine protein kinase
GII86_RS05105	COG2718	Belongs to the UPF0229 family
GII86_RS05110	COG1846	Transcriptional regulator
GII86_RS05115	COG1566	PFAM secretion protein HlyD family protein
GII86_RS05120	COG2814	Major facilitator Superfamily
GII86_RS05125	COG0655	NAD(P)H dehydrogenase (quinone) activity
GII86_RS05145	COG1725	Transcriptional regulator
GII86_RS05150	COG1131	(ABC) transporter
GII86_RS05155	COG1131	(ABC) transporter
GII86_RS05160	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GII86_RS05165	COG1278	Cold shock
GII86_RS05175	COG3706	GGDEF domain
GII86_RS05180	COG1823	symporter activity
GII86_RS05215	COG5577	PFAM Coat F domain
GII86_RS05220	COG0737	Belongs to the 5'-nucleotidase family
GII86_RS05220	COG4085	toxin activity
GII86_RS05220	COG1525	nuclease
GII86_RS05225	COG3764	Sortase (surface protein transpeptidase)
GII86_RS05230	COG0564	pseudouridine synthase activity
GII86_RS05240	COG0517	IMP dehydrogenase activity
GII86_RS05245	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GII86_RS05250	COG3153	acetyltransferase
GII86_RS05250	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GII86_RS05255	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GII86_RS05260	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GII86_RS05265	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GII86_RS05270	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GII86_RS05275	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GII86_RS05280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GII86_RS05285	COG4585	Histidine kinase
GII86_RS05285	COG2203	Gaf domain
GII86_RS05290	COG2197	response regulator
GII86_RS05295	COG0431	NADPH-dependent FMN reductase
GII86_RS05310	COG0791	NLP P60 protein
GII86_RS05310	COG1388	LysM domain
GII86_RS05315	COG1959	2 iron, 2 sulfur cluster binding
GII86_RS05320	COG0668	transmembrane transport
GII86_RS05325	COG2719	SpoVR family
GII86_RS05330	COG1785	Belongs to the alkaline phosphatase family
GII86_RS05335	COG1388	LysM domain
GII86_RS05335	COG0791	NLP P60 protein
GII86_RS05340	COG0583	DNA-binding transcription factor activity
GII86_RS05345	COG0372	Belongs to the citrate synthase family
GII86_RS05355	COG0531	amino acid
GII86_RS05360	COG0733	neurotransmitter:sodium symporter activity
GII86_RS05370	COG0456	acetyltransferase
GII86_RS05385	COG1595	DNA-templated transcription, initiation
GII86_RS05390	COG0667	Aldo Keto reductase
GII86_RS05395	COG0204	Acyl-transferase
GII86_RS05405	COG1253	flavin adenine dinucleotide binding
GII86_RS05410	COG0789	Transcriptional regulator
GII86_RS05415	COG0436	Aminotransferase
GII86_RS05420	COG1253	flavin adenine dinucleotide binding
GII86_RS05425	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GII86_RS05430	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GII86_RS05435	COG0584	glycerophosphoryl diester phosphodiesterase
GII86_RS05445	COG0668	transmembrane transport
GII86_RS05450	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GII86_RS05455	COG0726	polysaccharide deacetylase
GII86_RS05460	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII86_RS05465	COG1757	Na H antiporter
GII86_RS05470	COG0589	response to stress
GII86_RS05480	COG1132	(ABC) transporter
GII86_RS05485	COG1132	(ABC) transporter
GII86_RS05490	COG0702	epimerase
GII86_RS05510	COG0189	ligase activity
GII86_RS05515	COG0189	ligase activity
GII86_RS05520	COG4399	Belongs to the UPF0754 family
GII86_RS05525	COG3679	Belongs to the UPF0342 family
GII86_RS05530	COG4335	DNA alkylation repair
GII86_RS05535	COG0561	phosphatase activity
GII86_RS05540	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GII86_RS05545	COG0475	glutathione-regulated potassium exporter activity
GII86_RS05550	COG0490	domain, Protein
GII86_RS05560	COG1024	Enoyl-CoA hydratase
GII86_RS05570	COG4152	abc transporter atp-binding protein
GII86_RS05575	COG1668	transmembrane transport
GII86_RS05580	COG0420	3'-5' exonuclease activity
GII86_RS05585	COG4717	serine-type aminopeptidase activity
GII86_RS05590	COG3481	metal-dependent phosphohydrolase, HD sub domain
GII86_RS05600	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GII86_RS05630	COG1846	Transcriptional regulator
GII86_RS05635	COG4980	gas vesicle protein
GII86_RS05650	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GII86_RS05655	COG0537	adenosine 5'-monophosphoramidase activity
GII86_RS05660	COG1131	(ABC) transporter
GII86_RS05665	COG4473	ABC transporter
GII86_RS05675	COG1473	amidohydrolase
GII86_RS05680	COG3069	C4-dicarboxylate transmembrane transporter activity
GII86_RS05690	COG2329	Antibiotic biosynthesis monooxygenase
GII86_RS05695	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII86_RS05700	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GII86_RS05705	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GII86_RS05710	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GII86_RS05715	COG1309	transcriptional regulator
GII86_RS05720	COG1511	domain protein
GII86_RS05725	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GII86_RS05730	COG4377	Putative membrane peptidase family (DUF2324)
GII86_RS05740	COG1363	Peptidase, m42
GII86_RS05745	COG4405	Protein conserved in bacteria
GII86_RS05750	COG1301	dicarboxylic acid transport
GII86_RS05760	COG1234	tRNA 3'-trailer cleavage
GII86_RS05765	COG0095	Lipoate-protein ligase
GII86_RS05770	COG0702	epimerase
GII86_RS05775	COG0318	PFAM AMP-dependent synthetase and ligase
GII86_RS05785	COG0501	Belongs to the peptidase M48B family
GII86_RS05790	COG1404	Belongs to the peptidase S8 family
GII86_RS05795	COG0456	acetyltransferase
GII86_RS05800	COG0604	alcohol dehydrogenase
GII86_RS05805	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GII86_RS05810	COG0406	alpha-ribazole phosphatase activity
GII86_RS05815	COG0183	Belongs to the thiolase family
GII86_RS05820	COG0318	PFAM AMP-dependent synthetase and ligase
GII86_RS05825	COG1268	BioY protein
GII86_RS05830	COG0840	transmembrane signaling receptor activity
GII86_RS05835	COG0723	plastoquinol--plastocyanin reductase activity
GII86_RS05835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GII86_RS05840	COG1028	Short-chain dehydrogenase reductase Sdr
GII86_RS05850	COG4903	ComK protein
GII86_RS05855	COG1028	Short-chain dehydrogenase reductase Sdr
GII86_RS05865	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII86_RS05880	COG0398	Pfam SNARE associated Golgi protein
GII86_RS05885	COG0681	Belongs to the peptidase S26 family
GII86_RS05890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GII86_RS05895	COG1846	Transcriptional regulator
GII86_RS05905	COG0738	Major facilitator superfamily
GII86_RS05910	COG0673	inositol 2-dehydrogenase activity
GII86_RS05915	COG0561	phosphatase activity
GII86_RS05920	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GII86_RS05925	COG1609	Transcriptional regulator
GII86_RS05930	COG3180	Ammonia monooxygenase
GII86_RS05935	COG2814	Major facilitator Superfamily
GII86_RS05935	COG0477	Major facilitator Superfamily
GII86_RS05940	COG4533	DNA binding
GII86_RS05950	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
GII86_RS05955	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GII86_RS05960	COG1074	ATP-dependent DNA helicase activity
GII86_RS05965	COG0420	3'-5' exonuclease activity
GII86_RS05970	COG0419	ATPase involved in DNA repair
GII86_RS05975	COG1403	HNH endonuclease
GII86_RS06015	COG5337	Spore coat protein CotH
GII86_RS06020	COG0179	Fumarylacetoacetate (FAA) hydrolase
GII86_RS06030	COG1404	Belongs to the peptidase S8 family
GII86_RS06040	COG0367	asparagine synthase
GII86_RS06045	COG1562	ergosterol biosynthetic process
GII86_RS06050	COG0534	Mate efflux family protein
GII86_RS06055	COG2207	Transcriptional regulator
GII86_RS06055	COG1917	Cupin 2, conserved barrel domain protein
GII86_RS06060	COG1609	Transcriptional regulator
GII86_RS06065	COG0673	inositol 2-dehydrogenase activity
GII86_RS06070	COG2318	DinB family
GII86_RS06075	COG1279	arginine transmembrane transporter activity
GII86_RS06080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GII86_RS06085	COG1357	PFAM Pentapeptide repeats (8 copies)
GII86_RS06090	COG2267	carboxylic ester hydrolase activity
GII86_RS06095	COG0529	Catalyzes the synthesis of activated sulfate
GII86_RS06100	COG2046	Belongs to the sulfate adenylyltransferase family
GII86_RS06105	COG0175	sulfate reduction
GII86_RS06110	COG2045	Belongs to the ComB family
GII86_RS06115	COG1809	phosphosulfolactate synthase activity
GII86_RS06120	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII86_RS06125	COG4948	Mandelate Racemase Muconate Lactonizing
GII86_RS06130	COG2814	Major facilitator Superfamily
GII86_RS06135	COG0454	-acetyltransferase
GII86_RS06140	COG2153	protein acetylation
GII86_RS06145	COG0646	methionine synthase
GII86_RS06145	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GII86_RS06150	COG1666	GTP binding
GII86_RS06155	COG2996	Protein conserved in bacteria
GII86_RS06175	COG1695	Transcriptional regulator
GII86_RS06190	COG3227	Zinc metalloprotease (Elastase)
GII86_RS06195	COG1307	EDD domain protein, DegV family
GII86_RS06200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII86_RS06215	COG0561	phosphatase activity
GII86_RS06220	COG1073	alpha beta
GII86_RS06225	COG2151	metal-sulfur cluster biosynthetic enzyme
GII86_RS06235	COG0277	FAD linked oxidase domain protein
GII86_RS06240	COG2271	Major facilitator Superfamily
GII86_RS06245	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GII86_RS06250	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GII86_RS06260	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GII86_RS06265	COG0505	Belongs to the CarA family
GII86_RS06270	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GII86_RS06275	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GII86_RS06290	COG2267	carboxylic ester hydrolase activity
GII86_RS06300	COG1744	ABC transporter substrate-binding protein PnrA-like
GII86_RS06315	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GII86_RS06320	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GII86_RS06325	COG5504	Zn-dependent protease
GII86_RS06330	COG0444	Belongs to the ABC transporter superfamily
GII86_RS06335	COG4608	Belongs to the ABC transporter superfamily
GII86_RS06345	COG0601	transmembrane transport
GII86_RS06350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GII86_RS06360	COG0180	Tryptophanyl-tRNA synthetase
GII86_RS06365	COG4166	transmembrane transport
GII86_RS06370	COG0601	transmembrane transport
GII86_RS06375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GII86_RS06380	COG0444	Belongs to the ABC transporter superfamily
GII86_RS06385	COG4608	Belongs to the ABC transporter superfamily
GII86_RS06390	COG2814	Major facilitator Superfamily
GII86_RS06395	COG0456	acetyltransferase
GII86_RS06400	COG1393	Belongs to the ArsC family
GII86_RS06405	COG0861	Integral membrane protein TerC family
GII86_RS06415	COG4862	establishment of competence for transformation
GII86_RS06425	COG4469	Competence protein
GII86_RS06430	COG1164	Oligoendopeptidase f
GII86_RS06440	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GII86_RS06445	COG2346	COG2346, Truncated hemoglobins
GII86_RS06450	COG0741	lytic transglycosylase activity
GII86_RS06455	COG4116	CYTH
GII86_RS06465	COG2357	RelA SpoT domain protein
GII86_RS06470	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GII86_RS06475	COG0564	pseudouridine synthase activity
GII86_RS06480	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GII86_RS06485	COG0475	glutathione-regulated potassium exporter activity
GII86_RS06485	COG0569	domain protein
GII86_RS06490	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GII86_RS06495	COG0352	thiamine-phosphate diphosphorylase activity
GII86_RS06500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GII86_RS06505	COG2104	thiamine diphosphate biosynthetic process
GII86_RS06510	COG2022	thiamine diphosphate biosynthetic process
GII86_RS06515	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GII86_RS06520	COG0351	phosphomethylpyrimidine kinase
GII86_RS06525	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GII86_RS06580	COG0210	DNA helicase
GII86_RS06590	COG2153	protein acetylation
GII86_RS06595	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GII86_RS06600	COG2382	esterase
GII86_RS06605	COG0626	cystathionine gamma-synthase activity
GII86_RS06610	COG0626	cystathionine gamma-synthase activity
GII86_RS06615	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII86_RS06620	COG5505	Protein of unknown function (DUF819)
GII86_RS06650	COG1396	sequence-specific DNA binding
GII86_RS06715	COG0457	Tetratricopeptide repeat
GII86_RS06720	COG5444	nuclease activity
GII86_RS06780	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GII86_RS06790	COG3711	transcriptional antiterminator
GII86_RS06790	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII86_RS06795	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII86_RS06795	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII86_RS06795	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII86_RS06800	COG1482	cell wall glycoprotein biosynthetic process
GII86_RS06810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII86_RS06820	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GII86_RS06835	COG0109	protoheme IX farnesyltransferase activity
GII86_RS06845	COG0726	polysaccharide deacetylase
GII86_RS06860	COG5504	Zn-dependent protease
GII86_RS06865	COG2205	protein histidine kinase activity
GII86_RS06875	COG3383	formate dehydrogenase (NAD+) activity
GII86_RS06880	COG2427	Protein of unknown function (DUF1641)
GII86_RS06890	COG1051	belongs to the nudix hydrolase family
GII86_RS06900	COG2124	cytochrome p450
GII86_RS06905	COG1819	glycosyl
GII86_RS06915	COG1587	Uroporphyrinogen-III synthase
GII86_RS06920	COG0390	transport system, permease component
GII86_RS06925	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GII86_RS06930	COG0697	spore germination
GII86_RS06935	COG4297	protein containing double-stranded beta helix domain
GII86_RS06945	COG1252	NADH dehydrogenase
GII86_RS06950	COG1904	glucuronate isomerase
GII86_RS06955	COG2211	Major facilitator Superfamily
GII86_RS06960	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GII86_RS06970	COG1312	Catalyzes the dehydration of D-mannonate
GII86_RS06975	COG1028	Short-chain dehydrogenase reductase Sdr
GII86_RS06980	COG2271	Major facilitator Superfamily
GII86_RS06985	COG1609	Transcriptional regulator
GII86_RS06990	COG0246	Mannitol dehydrogenase
GII86_RS06995	COG2721	sulfolactate sulfo-lyase activity
GII86_RS07000	COG0730	response to heat
GII86_RS07005	COG2318	DinB family
GII86_RS07010	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GII86_RS07015	COG0457	Tetratricopeptide repeat
GII86_RS07030	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII86_RS07030	COG1388	LysM domain
GII86_RS07030	COG3409	Peptidoglycan-binding domain 1 protein
GII86_RS07040	COG4195	phage-related replication protein
GII86_RS07045	COG3546	catalase activity
GII86_RS07050	COG2856	Zn peptidase
GII86_RS07055	COG1396	sequence-specific DNA binding
GII86_RS07065	COG1522	sequence-specific DNA binding
GII86_RS07070	COG1484	DNA-dependent DNA replication
GII86_RS07090	COG1595	DNA-templated transcription, initiation
GII86_RS07095	COG3728	DNA packaging
GII86_RS07095	COG5484	DNA packaging
GII86_RS07100	COG1783	phage Terminase large subunit
GII86_RS07105	COG5518	Phage portal protein
GII86_RS07110	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GII86_RS07115	COG4653	Phage capsid family
GII86_RS07165	COG3953	SLT domain
GII86_RS07165	COG5412	phage tail tape measure protein
GII86_RS07165	COG5412	phage tail tape measure protein
GII86_RS07165	COG3953	SLT domain
GII86_RS07165	COG5412	phage tail tape measure protein
GII86_RS07165	COG3953	SLT domain
GII86_RS07170	COG1652	LysM domain
GII86_RS07175	COG4193	domain, Protein
GII86_RS07185	COG3628	GPW Gp25 family protein
GII86_RS07190	COG3299	homolog of phage Mu protein gp47
GII86_RS07195	COG3778	Protein conserved in bacteria
GII86_RS07235	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII86_RS07235	COG3409	Peptidoglycan-binding domain 1 protein
GII86_RS07255	COG0306	phosphate transporter
GII86_RS07260	COG1392	Phosphate transport regulator
GII86_RS07265	COG0531	amino acid
GII86_RS07270	COG0346	lactoylglutathione lyase activity
GII86_RS07275	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GII86_RS07280	COG0463	Glycosyl transferase, family 2
GII86_RS07285	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII86_RS07290	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII86_RS07295	COG2362	D-Aminopeptidase
GII86_RS07300	COG0601	transmembrane transport
GII86_RS07305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GII86_RS07310	COG0444	Belongs to the ABC transporter superfamily
GII86_RS07315	COG4166	transmembrane transport
GII86_RS07320	COG1619	proteins homologs of microcin C7 resistance protein MccF
GII86_RS07325	COG4948	Mandelate Racemase Muconate Lactonizing
GII86_RS07330	COG0791	NLP P60 protein
GII86_RS07335	COG4608	Belongs to the ABC transporter superfamily
GII86_RS07340	COG2706	6-phosphogluconolactonase activity
GII86_RS07350	COG1607	acyl-coa hydrolase
GII86_RS07355	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GII86_RS07355	COG1017	nitric oxide dioxygenase activity
GII86_RS07365	COG2323	membrane
GII86_RS07370	COG2318	DinB family
GII86_RS07375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII86_RS07380	COG2076	Multidrug Resistance protein
GII86_RS07385	COG2076	Multidrug Resistance protein
GII86_RS07390	COG0788	formyltetrahydrofolate deformylase activity
GII86_RS07395	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GII86_RS07400	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GII86_RS07405	COG1764	response to oxidative stress
GII86_RS07410	COG1846	Transcriptional regulator
GII86_RS07415	COG1764	response to oxidative stress
GII86_RS07425	COG0590	tRNA wobble adenosine to inosine editing
GII86_RS07430	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GII86_RS07435	COG1404	Belongs to the peptidase S8 family
GII86_RS07440	COG1366	Belongs to the anti-sigma-factor antagonist family
GII86_RS07445	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GII86_RS07450	COG1122	ATPase activity
GII86_RS07455	COG4721	ABC-type cobalt transport system, permease component
GII86_RS07465	COG0745	RESPONSE REGULATOR receiver
GII86_RS07470	COG3850	Histidine kinase
GII86_RS07470	COG5002	protein histidine kinase activity
GII86_RS07475	COG3212	peptidase
GII86_RS07480	COG3212	peptidase
GII86_RS07495	COG2239	Acts as a magnesium transporter
GII86_RS07500	COG0789	Transcriptional regulator
GII86_RS07515	COG1846	Transcriptional regulator
GII86_RS07520	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GII86_RS07525	COG0726	polysaccharide deacetylase
GII86_RS07530	COG1408	metallophosphoesterase
GII86_RS07540	COG0463	Glycosyl transferase, family 2
GII86_RS07545	COG1793	dna ligase
GII86_RS07545	COG3285	dna ligase
GII86_RS07550	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GII86_RS07560	COG0586	Pfam SNARE associated Golgi protein
GII86_RS07565	COG0861	Integral membrane protein TerC family
GII86_RS07570	COG1191	sigma factor activity
GII86_RS07590	COG0501	Belongs to the peptidase M48B family
GII86_RS07595	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GII86_RS07610	COG3594	Acyltransferase
GII86_RS07615	COG5002	protein histidine kinase activity
GII86_RS07620	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GII86_RS07630	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GII86_RS07635	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
GII86_RS07640	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GII86_RS07645	COG0436	Aminotransferase
GII86_RS07650	COG1850	ribulose-bisphosphate carboxylase activity
GII86_RS07655	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
GII86_RS07660	COG0235	Class ii aldolase
GII86_RS07665	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
GII86_RS07670	COG3339	Conserved Protein
GII86_RS07685	COG3852	Histidine kinase
GII86_RS07690	COG1846	Transcriptional regulator
GII86_RS07695	COG1360	Flagellar Motor Protein
GII86_RS07700	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GII86_RS07705	COG0542	response to heat
GII86_RS07710	COG3949	Membrane
GII86_RS07715	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GII86_RS07720	COG0720	synthase
GII86_RS07725	COG0602	queuosine metabolic process
GII86_RS07730	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GII86_RS07735	COG1733	regulation of RNA biosynthetic process
GII86_RS07740	COG1028	Short-chain dehydrogenase reductase Sdr
GII86_RS07810	COG4873	Protein conserved in bacteria
GII86_RS07820	COG3773	Cell wall hydrolase
GII86_RS07825	COG2244	polysaccharide biosynthetic process
GII86_RS07830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII86_RS07835	COG2217	Heavy metal translocating P-type atpase
GII86_RS07845	COG0006	proline dipeptidase activity
GII86_RS07850	COG1609	Transcriptional regulator
GII86_RS07855	COG3711	transcriptional antiterminator
GII86_RS07860	COG1263	PTS System
GII86_RS07860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII86_RS07860	COG2190	(PTS) system
GII86_RS07865	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII86_RS07870	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GII86_RS07880	COG1533	DNA photolyase activity
GII86_RS07885	COG0456	acetyltransferase
GII86_RS07890	COG0840	transmembrane signaling receptor activity
GII86_RS07895	COG2084	Dehydrogenase
GII86_RS07900	COG2340	Cysteine-rich secretory protein family
GII86_RS07905	COG0768	penicillin binding
GII86_RS07910	COG4191	Histidine kinase
GII86_RS07915	COG0436	Aminotransferase
GII86_RS07925	COG0784	Response regulator, receiver
GII86_RS07925	COG0835	chemotaxis
GII86_RS07935	COG2814	Major facilitator Superfamily
GII86_RS07940	COG1376	ErfK ybiS ycfS ynhG family protein
GII86_RS07945	COG1408	metallophosphoesterase
GII86_RS07950	COG1028	Short-chain dehydrogenase reductase Sdr
GII86_RS07955	COG2200	EAL domain
GII86_RS07960	COG4703	Protein of unknown function (DUF1797)
GII86_RS07965	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
GII86_RS07975	COG0517	IMP dehydrogenase activity
GII86_RS07980	COG0583	DNA-binding transcription factor activity
GII86_RS07985	COG0716	FMN binding
GII86_RS07995	COG0716	FMN binding
GII86_RS08000	COG2171	N-acyltransferase activity
GII86_RS08005	COG1473	amidohydrolase
GII86_RS08015	COG0668	transmembrane transport
GII86_RS08020	COG0450	alkyl hydroperoxide reductase
GII86_RS08025	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII86_RS08040	COG0746	molybdenum cofactor guanylyltransferase activity
GII86_RS08045	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GII86_RS08050	COG0303	'Molybdopterin
GII86_RS08055	COG1763	Mo-molybdopterin cofactor biosynthetic process
GII86_RS08060	COG0314	molybdopterin synthase activity
GII86_RS08065	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GII86_RS08070	COG1132	(ABC) transporter
GII86_RS08075	COG1132	(ABC) transporter
GII86_RS08085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GII86_RS08090	COG1136	(ABC) transporter
GII86_RS08095	COG0577	efflux transmembrane transporter activity
GII86_RS08100	COG1349	DNA-binding transcription factor activity
GII86_RS08105	COG1105	Belongs to the carbohydrate kinase PfkB family
GII86_RS08110	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII86_RS08110	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GII86_RS08110	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII86_RS08115	COG0681	Belongs to the peptidase S26 family
GII86_RS08125	COG0488	(ABC) transporter
GII86_RS08130	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GII86_RS08135	COG2309	aminopeptidase activity
GII86_RS08145	COG1077	Cell shape determining protein MreB Mrl
GII86_RS08150	COG2002	toxin-antitoxin pair type II binding
GII86_RS08155	COG3852	Histidine kinase
GII86_RS08160	COG2105	PFAM AIG2 family protein
GII86_RS08160	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
GII86_RS08165	COG0569	domain protein
GII86_RS08170	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GII86_RS08175	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GII86_RS08180	COG5503	Protein of unknown function (DUF1447)
GII86_RS08185	COG0561	phosphatase activity
GII86_RS08190	COG0242	peptide deformylase activity
GII86_RS08200	COG0497	DNA recombination
GII86_RS08205	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GII86_RS08210	COG0022	dehydrogenase e1 component
GII86_RS08215	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII86_RS08220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GII86_RS08225	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII86_RS08235	COG1982	Orn Lys Arg decarboxylase major
GII86_RS08240	COG4476	Belongs to the UPF0223 family
GII86_RS08245	COG4493	Belongs to the UPF0637 family
GII86_RS08255	COG0483	inositol monophosphate 1-phosphatase activity
GII86_RS08265	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GII86_RS08275	COG1959	2 iron, 2 sulfur cluster binding
GII86_RS08300	COG1595	DNA-templated transcription, initiation
GII86_RS08320	COG1217	gtp-binding protein TYPA
GII86_RS08330	COG4896	Protein conserved in bacteria
GII86_RS08340	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GII86_RS08345	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GII86_RS08350	COG2066	Belongs to the glutaminase family
GII86_RS08355	COG4838	Belongs to the UPF0358 family
GII86_RS08360	COG0772	Belongs to the SEDS family
GII86_RS08365	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GII86_RS08370	COG1612	heme a metabolic process
GII86_RS08375	COG0109	protoheme IX farnesyltransferase activity
GII86_RS08380	COG2010	Cytochrome c
GII86_RS08380	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GII86_RS08385	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GII86_RS08390	COG1845	cytochrome c oxidase, subunit III
GII86_RS08395	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GII86_RS08400	COG3336	cytochrome c oxidase
GII86_RS08410	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
GII86_RS08415	COG2340	Cysteine-rich secretory protein family
GII86_RS08430	COG3679	Belongs to the UPF0342 family
GII86_RS08435	COG4471	UPF0298 protein
GII86_RS08440	COG0742	ribosomal rna small subunit methyltransferase
GII86_RS08445	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GII86_RS08450	COG3314	Sporulation integral membrane protein YlbJ
GII86_RS08455	COG1752	Esterase of the alpha-beta hydrolase superfamily
GII86_RS08460	COG3480	Lon protease (S16) C-terminal proteolytic domain
GII86_RS08465	COG1323	Belongs to the UPF0348 family
GII86_RS08475	COG1399	metal-binding, possibly nucleic acid-binding protein
GII86_RS08490	COG0454	-acetyltransferase
GII86_RS08495	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GII86_RS08500	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
GII86_RS08505	COG2001	Belongs to the MraZ family
GII86_RS08510	COG0275	rRNA processing
GII86_RS08515	COG4839	cell division protein FtsL
GII86_RS08520	COG0768	penicillin binding
GII86_RS08525	COG0768	penicillin binding
GII86_RS08530	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GII86_RS08535	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GII86_RS08540	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GII86_RS08545	COG0772	Belongs to the SEDS family
GII86_RS08550	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GII86_RS08555	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GII86_RS08560	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GII86_RS08565	COG3879	Bacterial protein of unknown function (DUF881)
GII86_RS08570	COG3879	Bacterial protein of unknown function (DUF881)
GII86_RS08575	COG3856	small basic protein
GII86_RS08580	COG0849	cell division
GII86_RS08585	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GII86_RS08590	COG4412	M6 family metalloprotease domain protein
GII86_RS08590	COG1404	Belongs to the peptidase S8 family
GII86_RS08600	COG1191	sigma factor activity
GII86_RS08605	COG1191	sigma factor activity
GII86_RS08610	COG1119	ATPase activity
GII86_RS08615	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII86_RS08620	COG1873	PFAM PRC-barrel domain
GII86_RS08625	COG1496	oxidoreductase activity
GII86_RS08630	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GII86_RS08635	COG1799	cell septum assembly
GII86_RS08640	COG0762	integral membrane protein
GII86_RS08645	COG2302	S4 RNA-binding domain
GII86_RS08650	COG3599	regulation of cell shape
GII86_RS08655	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GII86_RS08660	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GII86_RS08665	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GII86_RS08670	COG0564	pseudouridine synthase activity
GII86_RS08675	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GII86_RS08680	COG2233	PERMEase
GII86_RS08685	COG0540	Belongs to the ATCase OTCase family
GII86_RS08690	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GII86_RS08695	COG0505	Belongs to the CarA family
GII86_RS08700	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GII86_RS08705	COG0543	2 iron, 2 sulfur cluster binding
GII86_RS08710	COG0167	dihydroorotate dehydrogenase activity
GII86_RS08715	COG0284	orotidine-5'-phosphate decarboxylase activity
GII86_RS08720	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GII86_RS08725	COG0175	sulfate reduction
GII86_RS08730	COG0306	phosphate transporter
GII86_RS08735	COG2046	Belongs to the sulfate adenylyltransferase family
GII86_RS08740	COG0529	Catalyzes the synthesis of activated sulfate
GII86_RS08745	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GII86_RS08750	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
GII86_RS08755	COG1648	precorrin-2 dehydrogenase activity
GII86_RS08760	COG1293	RNA-binding protein homologous to eukaryotic snRNP
GII86_RS08765	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GII86_RS08770	COG1561	YicC-like family, N-terminal region
GII86_RS08780	COG0194	GDP metabolic process
GII86_RS08785	COG1758	RNA polymerase activity
GII86_RS08790	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GII86_RS08795	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GII86_RS08800	COG0242	peptide deformylase activity
GII86_RS08805	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GII86_RS08810	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GII86_RS08810	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GII86_RS08815	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GII86_RS08820	COG0631	protein serine/threonine phosphatase activity
GII86_RS08825	COG0515	serine threonine protein kinase
GII86_RS08825	COG2815	serine threonine protein kinase
GII86_RS08830	COG1162	GTPase activity
GII86_RS08835	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GII86_RS08840	COG1564	THIamine pyrophosphokinase
GII86_RS08850	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GII86_RS08855	COG1302	Protein conserved in bacteria
GII86_RS08860	COG1461	Dihydroxyacetone kinase
GII86_RS08865	COG1760	l-serine dehydratase
GII86_RS08870	COG1760	l-serine dehydratase
GII86_RS08875	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GII86_RS08880	COG2050	protein possibly involved in aromatic compounds catabolism
GII86_RS08880	COG1349	DNA-binding transcription factor activity
GII86_RS08885	COG0416	fatty acid biosynthetic process
GII86_RS08890	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GII86_RS08895	COG1028	Short-chain dehydrogenase reductase Sdr
GII86_RS08905	COG0571	ribonuclease III activity
GII86_RS08910	COG1196	nuclear chromosome segregation
GII86_RS08915	COG0552	protein localization to endoplasmic reticulum
GII86_RS08925	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GII86_RS08930	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GII86_RS08935	COG0228	four-way junction DNA binding
GII86_RS08940	COG1837	Belongs to the UPF0109 family
GII86_RS08950	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GII86_RS08955	COG0336	Belongs to the RNA methyltransferase TrmD family
GII86_RS08960	COG0335	large ribosomal subunit rRNA binding
GII86_RS08965	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GII86_RS08970	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GII86_RS08980	COG2257	FlhB HrpN YscU SpaS Family
GII86_RS08985	COG0045	succinate-CoA ligase (ADP-forming) activity
GII86_RS08990	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GII86_RS08995	COG0758	DNA mediated transformation
GII86_RS09000	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GII86_RS09005	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GII86_RS09010	COG4974	Belongs to the 'phage' integrase family
GII86_RS09015	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GII86_RS09020	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GII86_RS09025	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GII86_RS09030	COG1815	bacterial-type flagellum-dependent cell motility
GII86_RS09035	COG1558	bacterial-type flagellum-dependent cell motility
GII86_RS09040	COG1677	Flagellar hook-basal body complex protein FliE
GII86_RS09045	COG1766	The M ring may be actively involved in energy transduction
GII86_RS09050	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GII86_RS09055	COG1317	bacterial-type flagellum organization
GII86_RS09060	COG1157	protein secretion by the type III secretion system
GII86_RS09065	COG2882	bacterial-type flagellum organization
GII86_RS09070	COG3334	PFAM MgtE intracellular
GII86_RS09075	COG3144	bacterial-type flagellum assembly
GII86_RS09080	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GII86_RS09085	COG4786	Flagellar basal body rod
GII86_RS09090	COG1582	Flagellar protein (FlbD)
GII86_RS09095	COG1580	Controls the rotational direction of flagella during chemotaxis
GII86_RS09100	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GII86_RS09105	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GII86_RS09105	COG1776	CheC inhibitor of MCP methylation
GII86_RS09110	COG2201	protein-glutamate methylesterase activity
GII86_RS09115	COG3190	flagellar
GII86_RS09120	COG1338	Plays a role in the flagellum-specific transport system
GII86_RS09125	COG1987	bacterial-type flagellum assembly
GII86_RS09130	COG1684	flagellar biosynthetic protein fliR
GII86_RS09135	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GII86_RS09140	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GII86_RS09145	COG1419	protein localization to endoplasmic reticulum
GII86_RS09150	COG0455	bacterial-type flagellum organization
GII86_RS09155	COG2201	protein-glutamate methylesterase activity
GII86_RS09160	COG2198	Histidine kinase
GII86_RS09160	COG0643	Histidine kinase
GII86_RS09165	COG0835	chemotaxis
GII86_RS09170	COG1776	CheC inhibitor of MCP methylation
GII86_RS09175	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GII86_RS09180	COG1191	sigma factor activity
GII86_RS09190	COG0052	Belongs to the universal ribosomal protein uS2 family
GII86_RS09195	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GII86_RS09200	COG0528	UMP kinase activity
GII86_RS09205	COG0233	cytoplasmic translational termination
GII86_RS09210	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GII86_RS09215	COG4589	Belongs to the CDS family
GII86_RS09220	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GII86_RS09225	COG0750	zinc metalloprotease
GII86_RS09230	COG0442	prolyl-tRNA aminoacylation
GII86_RS09235	COG2176	DNA-directed DNA polymerase activity
GII86_RS09240	COG0779	Required for maturation of 30S ribosomal subunits
GII86_RS09245	COG0195	Participates in both transcription termination and antitermination
GII86_RS09250	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GII86_RS09255	COG1358	cellular component organization or biogenesis
GII86_RS09260	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GII86_RS09265	COG1550	Protein conserved in bacteria
GII86_RS09270	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GII86_RS09275	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GII86_RS09280	COG0196	riboflavin kinase activity
GII86_RS09285	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GII86_RS09290	COG1185	polyribonucleotide nucleotidyltransferase activity
GII86_RS09295	COG0726	polysaccharide deacetylase
GII86_RS09300	COG0612	Peptidase, M16
GII86_RS09305	COG1873	PFAM PRC-barrel domain
GII86_RS09310	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GII86_RS09315	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GII86_RS09320	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GII86_RS09325	COG0527	aspartate kinase activity
GII86_RS09330	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GII86_RS09335	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GII86_RS09340	COG0740	serine-type endopeptidase activity
GII86_RS09350	COG1674	ftsk spoiiie
GII86_RS09350	COG4980	gas vesicle protein
GII86_RS09355	COG2188	Transcriptional regulator
GII86_RS09360	COG2814	Major facilitator Superfamily
GII86_RS09365	COG0612	Peptidase, M16
GII86_RS09370	COG0612	Peptidase, M16
GII86_RS09375	COG0300	oxidoreductase activity
GII86_RS09390	COG1426	Protein conserved in bacteria
GII86_RS09395	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GII86_RS09400	COG1058	Belongs to the CinA family
GII86_RS09400	COG1546	Belongs to the CinA family
GII86_RS09405	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GII86_RS09410	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GII86_RS09415	COG1418	mRNA catabolic process
GII86_RS09420	COG1692	metallophosphoesterase
GII86_RS09425	COG2359	stage V sporulation protein S
GII86_RS09430	COG1063	alcohol dehydrogenase
GII86_RS09435	COG0156	8-amino-7-oxononanoate synthase activity
GII86_RS09440	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GII86_RS09445	COG4550	Control of competence regulator ComK, YlbF/YmcA
GII86_RS09455	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GII86_RS09460	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GII86_RS09490	COG0582	viral genome integration into host DNA
GII86_RS09535	COG3226	Transcriptional regulator
GII86_RS09545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII86_RS09550	COG1404	Belongs to the peptidase S8 family
GII86_RS09560	COG4195	phage-related replication protein
GII86_RS09565	COG1764	response to oxidative stress
GII86_RS09570	COG2076	Multidrug Resistance protein
GII86_RS09575	COG2076	Multidrug Resistance protein
GII86_RS09590	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GII86_RS09595	COG1923	regulation of RNA biosynthetic process
GII86_RS09610	COG1780	Probably involved in ribonucleotide reductase function
GII86_RS09615	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GII86_RS09620	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GII86_RS09625	COG4112	unkown
GII86_RS09630	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII86_RS09635	COG0464	growth
GII86_RS09640	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GII86_RS09645	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
GII86_RS09650	COG0789	Transcriptional regulator
GII86_RS09655	COG0174	glutamine synthetase
GII86_RS09675	COG4282	regulation of fungal-type cell wall biogenesis
GII86_RS09690	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII86_RS09705	COG3655	Transcriptional regulator
GII86_RS09730	COG0135	phosphoribosylanthranilate isomerase activity
GII86_RS09735	COG2211	Major facilitator Superfamily
GII86_RS09740	COG3507	Belongs to the glycosyl hydrolase 43 family
GII86_RS09745	COG1940	carbohydrate kinase activity
GII86_RS09750	COG2115	Belongs to the xylose isomerase family
GII86_RS09755	COG1070	Carbohydrate kinase
GII86_RS09765	COG1525	nuclease
GII86_RS09770	COG2814	Major facilitator Superfamily
GII86_RS09775	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GII86_RS09790	COG0756	dUTP diphosphatase activity
GII86_RS09830	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GII86_RS09840	COG3832	glyoxalase III activity
GII86_RS09850	COG0697	spore germination
GII86_RS09880	COG4195	phage-related replication protein
GII86_RS09890	COG0346	lactoylglutathione lyase activity
GII86_RS09895	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GII86_RS09900	COG1388	LysM domain
GII86_RS09905	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GII86_RS09910	COG4224	UPF0291 protein
GII86_RS09915	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GII86_RS09925	COG3763	UPF0154 protein
GII86_RS09935	COG0785	Cytochrome C biogenesis protein
GII86_RS09940	COG2201	protein-glutamate methylesterase activity
GII86_RS09945	COG4846	Membrane protein involved in cytochrome C biogenesis
GII86_RS09955	COG0071	Belongs to the small heat shock protein (HSP20) family
GII86_RS09970	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GII86_RS09975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII86_RS09995	COG0824	Thioesterase
GII86_RS10005	COG4841	protein insertion into membrane
GII86_RS10010	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GII86_RS10015	COG1832	CoA-binding protein
GII86_RS10020	COG0187	DNA topoisomerase II activity
GII86_RS10025	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GII86_RS10035	COG1115	amino acid carrier protein
GII86_RS10040	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
GII86_RS10050	COG5520	Belongs to the glycosyl hydrolase 30 family
GII86_RS10055	COG3507	Belongs to the glycosyl hydrolase 43 family
GII86_RS10060	COG2246	polysaccharide biosynthetic process
GII86_RS10065	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GII86_RS10070	COG0586	Pfam SNARE associated Golgi protein
GII86_RS10075	COG2404	hydrolase activity, acting on ester bonds
GII86_RS10080	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GII86_RS10085	COG1024	Enoyl-CoA hydratase
GII86_RS10090	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GII86_RS10095	COG0511	ligase activity, forming carbon-carbon bonds
GII86_RS10100	COG0439	Biotin carboxylase
GII86_RS10105	COG0318	PFAM AMP-dependent synthetase and ligase
GII86_RS10110	COG1960	acyl-CoA dehydrogenase activity
GII86_RS10125	COG1649	PFAM Uncharacterised BCR, COG1649
GII86_RS10135	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII86_RS10135	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GII86_RS10140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII86_RS10145	COG2027	D-alanyl-D-alanine carboxypeptidase
GII86_RS10150	COG2017	converts alpha-aldose to the beta-anomer
GII86_RS10155	COG0534	Mate efflux family protein
GII86_RS10170	COG0582	viral genome integration into host DNA
GII86_RS10175	COG0166	Belongs to the GPI family
GII86_RS10180	COG0405	Gamma-glutamyltransferase
GII86_RS10185	COG0583	DNA-binding transcription factor activity
GII86_RS10190	COG0604	alcohol dehydrogenase
GII86_RS10195	COG0493	'glutamate synthase
GII86_RS10200	COG0070	glutamate synthase
GII86_RS10200	COG0069	glutamate synthase activity
GII86_RS10200	COG0067	glutamate synthase
GII86_RS10205	COG0583	DNA-binding transcription factor activity
GII86_RS10210	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GII86_RS10215	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII86_RS10225	COG0300	oxidoreductase activity
GII86_RS10230	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GII86_RS10240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII86_RS10255	COG1131	(ABC) transporter
GII86_RS10265	COG2814	Major facilitator Superfamily
GII86_RS10270	COG1070	Carbohydrate kinase
GII86_RS10275	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GII86_RS10280	COG0243	molybdopterin cofactor binding
GII86_RS10290	COG2814	Major facilitator Superfamily
GII86_RS10295	COG0673	inositol 2-dehydrogenase activity
GII86_RS10300	COG1082	Xylose isomerase domain protein TIM barrel
GII86_RS10305	COG1609	Transcriptional regulator
GII86_RS10325	COG0840	transmembrane signaling receptor activity
GII86_RS10325	COG5278	phosphoserine phosphatase activity
GII86_RS10330	COG2368	4-hydroxyphenylacetate
GII86_RS10335	COG4305	rare lipoprotein A
GII86_RS10340	COG3619	membrane
GII86_RS10345	COG3866	Pectate lyase
GII86_RS10350	COG2135	peptidase activity
GII86_RS10355	COG2140	Oxalate decarboxylase
GII86_RS10380	COG2720	vancomycin resistance protein
GII86_RS10395	COG3739	integral membrane protein
GII86_RS10400	COG0583	DNA-binding transcription factor activity
GII86_RS10405	COG0697	spore germination
GII86_RS10415	COG0693	protein deglycase activity
GII86_RS10420	COG2367	Beta-lactamase
GII86_RS10445	COG0726	polysaccharide deacetylase
GII86_RS10450	COG2314	TM2 domain
GII86_RS10555	COG0457	Tetratricopeptide repeat
GII86_RS10560	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GII86_RS10570	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GII86_RS10575	COG2226	methyltransferase
GII86_RS10580	COG2211	Major facilitator Superfamily
GII86_RS10630	COG5444	nuclease activity
GII86_RS10635	COG4282	regulation of fungal-type cell wall biogenesis
GII86_RS10640	COG1231	oxidoreductase activity
GII86_RS10645	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII86_RS10650	COG0662	Cupin 2, conserved barrel domain protein
GII86_RS10650	COG2207	Transcriptional regulator
GII86_RS10655	COG0456	acetyltransferase
GII86_RS10660	COG1309	transcriptional regulator
GII86_RS10665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII86_RS10670	COG3708	Transcriptional regulator
GII86_RS10675	COG2378	regulation of single-species biofilm formation
GII86_RS10685	COG0640	Transcriptional regulator
GII86_RS10690	COG0741	lytic transglycosylase activity
GII86_RS10695	COG2322	membrane
GII86_RS10710	COG1619	proteins homologs of microcin C7 resistance protein MccF
GII86_RS10715	COG3239	Fatty acid desaturase
GII86_RS10720	COG4585	Histidine kinase
GII86_RS10725	COG2197	response regulator
GII86_RS10730	COG3584	3D domain protein
GII86_RS10730	COG1388	LysM domain
GII86_RS10735	COG0514	ATP-dependent DNA helicase (RecQ)
GII86_RS10745	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GII86_RS10750	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GII86_RS10765	COG0071	Belongs to the small heat shock protein (HSP20) family
GII86_RS10790	COG1012	belongs to the aldehyde dehydrogenase family
GII86_RS10795	COG1657	PFAM Prenyltransferase squalene oxidase
GII86_RS10800	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GII86_RS10805	COG0733	neurotransmitter:sodium symporter activity
GII86_RS10810	COG0385	Bile acid
GII86_RS10815	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII86_RS10820	COG0567	Dehydrogenase, E1 component
GII86_RS10825	COG4548	von Willebrand factor, type A
GII86_RS10830	COG0714	Associated with various cellular activities
GII86_RS10835	COG2032	superoxide dismutase activity
GII86_RS10840	COG1388	LysM domain
GII86_RS10840	COG0791	NLP P60 protein
GII86_RS10845	COG1819	glycosyl
GII86_RS10850	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GII86_RS10855	COG0534	Mate efflux family protein
GII86_RS10860	COG1366	Belongs to the anti-sigma-factor antagonist family
GII86_RS10865	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GII86_RS10870	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GII86_RS10880	COG2962	Rard protein
GII86_RS10900	COG1942	4-Oxalocrotonate Tautomerase
GII86_RS10905	COG1733	regulation of RNA biosynthetic process
GII86_RS10910	COG0778	Nitroreductase
GII86_RS10915	COG0400	carboxylic ester hydrolase activity
GII86_RS10920	COG0346	lactoylglutathione lyase activity
GII86_RS10930	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII86_RS10935	COG0793	Belongs to the peptidase S41A family
GII86_RS10935	COG3409	Peptidoglycan-binding domain 1 protein
GII86_RS10940	COG2226	methyltransferase
GII86_RS10950	COG1876	peptidase activity
GII86_RS10955	COG0813	purine-nucleoside phosphorylase activity
GII86_RS10970	COG0671	phosphoesterase, PA-phosphatase related
GII86_RS10990	COG4479	Belongs to the UPF0346 family
GII86_RS11000	COG1509	lysine 2,3-aminomutase activity
GII86_RS11005	COG0456	acetyltransferase
GII86_RS11010	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII86_RS11015	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GII86_RS11020	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GII86_RS11025	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GII86_RS11040	COG0456	acetyltransferase
GII86_RS11045	COG0463	Glycosyl transferase, family 2
GII86_RS11060	COG4641	Protein conserved in bacteria
GII86_RS11065	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
GII86_RS11070	COG1086	Polysaccharide biosynthesis protein
GII86_RS11075	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GII86_RS11080	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GII86_RS11085	COG1846	Transcriptional regulator
GII86_RS11090	COG0534	Mate efflux family protein
GII86_RS11100	COG4698	Protein conserved in bacteria
GII86_RS11105	COG2755	lipolytic protein G-D-S-L family
GII86_RS11110	COG1999	signal sequence binding
GII86_RS11120	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GII86_RS11125	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GII86_RS11130	COG1272	protein, Hemolysin III
GII86_RS11135	COG0204	Acyl-transferase
GII86_RS11140	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GII86_RS11145	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GII86_RS11155	COG2136	Putative SAM-dependent methyltransferase
GII86_RS11155	COG2521	methyltransferase
GII86_RS11165	COG0129	dihydroxy-acid dehydratase activity
GII86_RS11170	COG1413	lyase activity
GII86_RS11175	COG1418	mRNA catabolic process
GII86_RS11180	COG0386	Belongs to the glutathione peroxidase family
GII86_RS11185	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GII86_RS11190	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GII86_RS11200	COG1278	Cold shock
GII86_RS11220	COG0328	RNA-DNA hybrid ribonuclease activity
GII86_RS11225	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GII86_RS11230	COG0328	RNA-DNA hybrid ribonuclease activity
GII86_RS11240	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GII86_RS11255	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GII86_RS11265	COG1755	Isoprenylcysteine carboxyl methyltransferase
GII86_RS11270	COG3424	synthase
GII86_RS11275	COG2233	PERMEase
GII86_RS11280	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GII86_RS11285	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GII86_RS11295	COG0800	Aldolase
GII86_RS11300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII86_RS11305	COG1609	Transcriptional regulator
GII86_RS11310	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
GII86_RS11315	COG1028	Short-chain dehydrogenase reductase Sdr
GII86_RS11320	COG1199	ATP-dependent helicase activity
GII86_RS11335	COG0116	Belongs to the methyltransferase superfamily
GII86_RS11350	COG4474	Belongs to the UPF0398 family
GII86_RS11365	COG3359	exonuclease
GII86_RS11370	COG1205	dead DEAH box helicase
GII86_RS11370	COG1111	helicase
GII86_RS11375	COG2190	(PTS) system
GII86_RS11380	COG0071	Belongs to the small heat shock protein (HSP20) family
GII86_RS11415	COG3331	DNA recombination
GII86_RS11420	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII86_RS11420	COG4499	WXG100 protein secretion system (Wss), protein YukC
GII86_RS11430	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GII86_RS11435	COG3935	DnaD domain protein
GII86_RS11440	COG0017	Asparaginyl-tRNA synthetase
GII86_RS11445	COG0436	Aminotransferase
GII86_RS11450	COG5353	protein conserved in bacteria
GII86_RS11460	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GII86_RS11460	COG1199	ATP-dependent helicase activity
GII86_RS11465	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GII86_RS11470	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GII86_RS11475	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GII86_RS11480	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GII86_RS11480	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GII86_RS11485	COG0617	tRNA 3'-terminal CCA addition
GII86_RS11490	COG0438	transferase activity, transferring glycosyl groups
GII86_RS11495	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GII86_RS11500	COG1803	Methylglyoxal synthase
GII86_RS11505	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GII86_RS11510	COG1694	Mazg nucleotide pyrophosphohydrolase
GII86_RS11515	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII86_RS11525	COG4347	Protein of unknown function (DUF1405)
GII86_RS11530	COG2010	Cytochrome c
GII86_RS11530	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GII86_RS11535	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GII86_RS11540	COG0723	plastoquinol--plastocyanin reductase activity
GII86_RS11550	COG5582	Belongs to the UPF0302 family
GII86_RS11555	COG0457	Tetratricopeptide repeat
GII86_RS11560	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GII86_RS11565	COG0287	Prephenate dehydrogenase
GII86_RS11580	COG0133	tryptophan synthase activity
GII86_RS11585	COG0135	phosphoribosylanthranilate isomerase activity
GII86_RS11595	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GII86_RS11600	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GII86_RS11605	COG4401	Chorismate mutase type I
GII86_RS11610	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GII86_RS11615	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GII86_RS11620	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GII86_RS11625	COG0105	UTP biosynthetic process
GII86_RS11630	COG0142	geranyltranstransferase activity
GII86_RS11635	COG2226	methyltransferase
GII86_RS11640	COG0142	geranyltranstransferase activity
GII86_RS11650	COG0302	gtp cyclohydrolase
GII86_RS11655	COG0776	regulation of translation
GII86_RS11660	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GII86_RS11675	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GII86_RS11680	COG1160	GTP binding
GII86_RS11705	COG1304	FMN binding
GII86_RS11710	COG0539	negative regulation of cytoplasmic translation
GII86_RS11715	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GII86_RS11725	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
GII86_RS11730	COG2959	enzyme of heme biosynthesis
GII86_RS11735	COG3773	Cell wall hydrolase
GII86_RS11735	COG3409	Peptidoglycan-binding domain 1 protein
GII86_RS11740	COG2339	peptidase activity
GII86_RS11745	COG0492	ferredoxin-NADP+ reductase activity
GII86_RS11750	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GII86_RS11755	COG4862	establishment of competence for transformation
GII86_RS11760	COG1408	metallophosphoesterase
GII86_RS11770	COG1388	LysM domain
GII86_RS11775	COG1266	CAAX protease self-immunity
GII86_RS11780	COG0514	ATP-dependent DNA helicase (RecQ)
GII86_RS11785	COG4955	Helix-turn-helix domain
GII86_RS11790	COG1141	Ferredoxin
GII86_RS11795	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GII86_RS11800	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GII86_RS11805	COG0710	3-dehydroquinate dehydratase activity
GII86_RS11815	COG1595	DNA-templated transcription, initiation
GII86_RS11820	COG5002	protein histidine kinase activity
GII86_RS11825	COG0745	RESPONSE REGULATOR receiver
GII86_RS11830	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GII86_RS11835	COG1333	cytochrome c biogenesis protein
GII86_RS11840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII86_RS11845	COG1187	pseudouridine synthase activity
GII86_RS11850	COG0700	Nucleoside recognition
GII86_RS11855	COG2715	membrane protein required for spore maturation
GII86_RS11860	COG1686	Belongs to the peptidase S11 family
GII86_RS11870	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GII86_RS11875	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GII86_RS11880	COG1547	Domain of unknown function (DUF309)
GII86_RS11885	COG0456	acetyltransferase
GII86_RS11890	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GII86_RS11895	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GII86_RS11895	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GII86_RS11900	COG0307	riboflavin synthase, alpha
GII86_RS11905	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GII86_RS11905	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GII86_RS11915	COG0681	Belongs to the peptidase S26 family
GII86_RS11920	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
GII86_RS11955	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GII86_RS11960	COG4086	secreted protein
GII86_RS11965	COG0019	diaminopimelate decarboxylase activity
GII86_RS11970	COG0697	spore germination
GII86_RS11985	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GII86_RS12005	COG1191	sigma factor activity
GII86_RS12010	COG2172	sigma factor antagonist activity
GII86_RS12015	COG1366	Belongs to the anti-sigma-factor antagonist family
GII86_RS12020	COG1686	Belongs to the peptidase S11 family
GII86_RS12025	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GII86_RS12030	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GII86_RS12035	COG4974	Belongs to the 'phage' integrase family
GII86_RS12045	COG0735	belongs to the Fur family
GII86_RS12050	COG1300	Membrane
GII86_RS12060	COG0281	malic enzyme
GII86_RS12065	COG1757	Na H antiporter
GII86_RS12070	COG1027	Aspartate ammonia-lyase
GII86_RS12075	COG0252	asparaginase activity
GII86_RS12080	COG1396	sequence-specific DNA binding
GII86_RS12085	COG1379	DNA repair
GII86_RS12090	COG0494	nUDIX hydrolase
GII86_RS12100	COG0667	Aldo Keto reductase
GII86_RS12110	COG1073	alpha beta
GII86_RS12120	COG4918	Iron-sulphur cluster biosynthesis
GII86_RS12125	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GII86_RS12125	COG0456	acetyltransferase
GII86_RS12130	COG2329	Antibiotic biosynthesis monooxygenase
GII86_RS12135	COG0456	acetyltransferase
GII86_RS12145	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GII86_RS12160	COG0346	lactoylglutathione lyase activity
GII86_RS12165	COG1072	(Pantothenic acid kinase))
GII86_RS12170	COG3048	D-serine ammonia-lyase activity
GII86_RS12175	COG0300	oxidoreductase activity
GII86_RS12180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII86_RS12185	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII86_RS12190	COG4187	Peptidase family M20/M25/M40
GII86_RS12195	COG1902	pentaerythritol trinitrate reductase activity
GII86_RS12200	COG0596	Alpha beta hydrolase
GII86_RS12210	COG1234	tRNA 3'-trailer cleavage
GII86_RS12215	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GII86_RS12220	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GII86_RS12225	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GII86_RS12235	COG0706	membrane insertase activity
GII86_RS12240	COG3361	conserved protein (COG2071)
GII86_RS12245	COG2195	Cleaves the N-terminal amino acid of tripeptides
GII86_RS12250	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GII86_RS12255	COG0346	lactoylglutathione lyase activity
GII86_RS12265	COG1376	ErfK ybiS ycfS ynhG family protein
GII86_RS12270	COG4129	membrane
GII86_RS12275	COG1126	abc transporter atp-binding protein
GII86_RS12280	COG0765	amino acid transport
GII86_RS12285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII86_RS12295	COG1597	lipid kinase activity
GII86_RS12300	COG2814	Major facilitator Superfamily
GII86_RS12305	COG0789	Transcriptional regulator
GII86_RS12305	COG4978	Transcriptional regulator
GII86_RS12310	COG0508	dehydrogenase complex catalyzes the overall conversion of
GII86_RS12315	COG0022	dehydrogenase e1 component
GII86_RS12320	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GII86_RS12325	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GII86_RS12330	COG3426	butyrate kinase activity
GII86_RS12335	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GII86_RS12340	COG0280	phosphate acetyltransferase
GII86_RS12345	COG3290	protein histidine kinase activity
GII86_RS12345	COG3829	transcription factor binding
GII86_RS12355	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GII86_RS12360	COG2079	MmgE PrpD family protein
GII86_RS12365	COG0372	Belongs to the citrate synthase family
GII86_RS12370	COG1960	acyl-CoA dehydrogenase activity
GII86_RS12375	COG1250	3-hydroxyacyl-CoA dehydrogenase
GII86_RS12380	COG0183	Belongs to the thiolase family
GII86_RS12385	COG0584	glycerophosphoryl diester phosphodiesterase
GII86_RS12390	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII86_RS12405	COG1902	pentaerythritol trinitrate reductase activity
GII86_RS12410	COG0745	RESPONSE REGULATOR receiver
GII86_RS12415	COG0750	zinc metalloprotease
GII86_RS12420	COG0497	DNA recombination
GII86_RS12425	COG1438	arginine binding
GII86_RS12430	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GII86_RS12435	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GII86_RS12440	COG0142	geranyltranstransferase activity
GII86_RS12445	COG1722	exodeoxyribonuclease VII activity
GII86_RS12450	COG1570	exodeoxyribonuclease VII activity
GII86_RS12455	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GII86_RS12460	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GII86_RS12465	COG1302	Protein conserved in bacteria
GII86_RS12470	COG0439	Biotin carboxylase
GII86_RS12475	COG0511	ligase activity, forming carbon-carbon bonds
GII86_RS12515	COG3854	ATPases associated with a variety of cellular activities
GII86_RS12525	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GII86_RS12530	COG0006	proline dipeptidase activity
GII86_RS12535	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GII86_RS12545	COG3872	metal-dependent enzyme
GII86_RS12555	COG1752	Esterase of the alpha-beta hydrolase superfamily
GII86_RS12560	COG1321	iron dependent repressor
GII86_RS12565	COG0095	Lipoate-protein ligase
GII86_RS12570	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII86_RS12575	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GII86_RS12580	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GII86_RS12585	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GII86_RS12590	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GII86_RS12605	COG1396	sequence-specific DNA binding
GII86_RS12615	COG0681	Belongs to the peptidase S26 family
GII86_RS12640	COG4940	Competence protein ComGF
GII86_RS12650	COG4970	Tfp pilus assembly protein FimT
GII86_RS12655	COG4537	Required for transformation and DNA binding
GII86_RS12660	COG1459	type II secretion system
GII86_RS12665	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GII86_RS12670	COG0517	IMP dehydrogenase activity
GII86_RS12675	COG0598	Magnesium transport protein CorA
GII86_RS12680	COG1253	flavin adenine dinucleotide binding
GII86_RS12685	COG1366	Belongs to the anti-sigma-factor antagonist family
GII86_RS12695	COG1393	Belongs to the ArsC family
GII86_RS12705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII86_RS12715	COG0011	TIGRFAM Protein of
GII86_RS12725	COG2866	Carboxypeptidase
GII86_RS12735	COG1940	carbohydrate kinase activity
GII86_RS12740	COG4483	Protein conserved in bacteria
GII86_RS12745	COG0457	Tetratricopeptide repeat
GII86_RS12745	COG0705	Rhomboid family
GII86_RS12755	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GII86_RS12765	COG0438	transferase activity, transferring glycosyl groups
GII86_RS12780	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GII86_RS12785	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GII86_RS12790	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GII86_RS12795	COG0581	inorganic phosphate transmembrane transporter activity
GII86_RS12800	COG0573	inorganic phosphate transmembrane transporter activity
GII86_RS12805	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GII86_RS12810	COG0768	penicillin binding
GII86_RS12815	COG0477	Major facilitator Superfamily
GII86_RS12820	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GII86_RS12825	COG2839	Protein conserved in bacteria
GII86_RS12830	COG5521	maltodextrose utilization protein MalA
GII86_RS12835	COG1388	LysM domain
GII86_RS12840	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GII86_RS12845	COG4709	membrane
GII86_RS12850	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
GII86_RS12855	COG0735	belongs to the Fur family
GII86_RS12860	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII86_RS12870	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GII86_RS12875	COG0513	Belongs to the DEAD box helicase family
GII86_RS12885	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GII86_RS12890	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GII86_RS12895	COG2384	SAM-dependent methyltransferase
GII86_RS12900	COG2010	Cytochrome c
GII86_RS12905	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GII86_RS12910	COG0358	DNA primase activity
GII86_RS12915	COG1671	Belongs to the UPF0178 family
GII86_RS12920	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GII86_RS12925	COG0517	IMP dehydrogenase activity
GII86_RS12930	COG0751	glycine-tRNA ligase activity
GII86_RS12935	COG0752	glycyl-tRNA synthetase alpha subunit
GII86_RS12940	COG1381	Involved in DNA repair and RecF pathway recombination
GII86_RS12950	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GII86_RS12955	COG0295	cytidine deaminase activity
GII86_RS12960	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GII86_RS12965	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GII86_RS12970	COG1480	7TM receptor with intracellular HD hydrolase
GII86_RS12975	COG1702	phosphate starvation-inducible protein PhoH
GII86_RS12980	COG0561	phosphatase activity
GII86_RS12995	COG4864	UPF0365 protein
GII86_RS13000	COG1030	water channel activity
GII86_RS13005	COG1610	YqeY-like protein
GII86_RS13015	COG1283	sodium-dependent phosphate transmembrane transporter activity
GII86_RS13020	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GII86_RS13025	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GII86_RS13030	COG2264	protein methyltransferase activity
GII86_RS13035	COG0484	heat shock protein binding
GII86_RS13040	COG0443	Heat shock 70 kDa protein
GII86_RS13045	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GII86_RS13050	COG1420	regulation of RNA biosynthetic process
GII86_RS13055	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GII86_RS13060	COG0481	GTPase activity
GII86_RS13070	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII86_RS13075	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GII86_RS13080	COG0268	Binds directly to 16S ribosomal RNA
GII86_RS13085	COG1466	dna polymerase III delta subunit
GII86_RS13100	COG0658	competence protein
GII86_RS13100	COG2333	competence protein COMEC
GII86_RS13105	COG2131	deaminase
GII86_RS13110	COG1555	photosystem II stabilization
GII86_RS13110	COG1596	polysaccharide export
GII86_RS13115	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GII86_RS13120	COG2226	methyltransferase
GII86_RS13125	COG0799	negative regulation of ribosome biogenesis
GII86_RS13130	COG1713	HD superfamily hydrolase involved in NAD metabolism
GII86_RS13135	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GII86_RS13140	COG1534	Rna-binding protein
GII86_RS13145	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GII86_RS13150	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GII86_RS13155	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GII86_RS13165	COG2755	lipolytic protein G-D-S-L family
GII86_RS13170	COG3409	Peptidoglycan-binding domain 1 protein
GII86_RS13170	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII86_RS13175	COG0398	Pfam SNARE associated Golgi protein
GII86_RS13180	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GII86_RS13190	COG3209	COG3209 Rhs family protein
GII86_RS13200	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GII86_RS13205	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GII86_RS13210	COG0798	PFAM Bile acid sodium symporter
GII86_RS13215	COG0346	lactoylglutathione lyase activity
GII86_RS13220	COG0640	Transcriptional regulator
GII86_RS13225	COG3403	YqcI/YcgG family
GII86_RS13230	COG0457	Tetratricopeptide repeat
GII86_RS13245	COG5444	nuclease activity
GII86_RS13265	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII86_RS13265	COG3409	Peptidoglycan-binding domain 1 protein
GII86_RS13270	COG4824	toxin secretion phage lysis holin
GII86_RS13300	COG3778	Protein conserved in bacteria
GII86_RS13305	COG3299	homolog of phage Mu protein gp47
GII86_RS13310	COG3628	GPW Gp25 family protein
GII86_RS13320	COG4193	domain, Protein
GII86_RS13325	COG1652	LysM domain
GII86_RS13330	COG3953	SLT domain
GII86_RS13330	COG5280	Phage tail tape measure protein TP901
GII86_RS13395	COG4653	Phage capsid family
GII86_RS13400	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GII86_RS13410	COG2369	cell adhesion
GII86_RS13415	COG5518	Phage portal protein
GII86_RS13420	COG1783	phage Terminase large subunit
GII86_RS13425	COG5484	DNA packaging
GII86_RS13435	COG3677	Transposase
GII86_RS13450	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
GII86_RS13460	COG1484	DNA-dependent DNA replication
GII86_RS13465	COG3935	DnaD domain protein
GII86_RS13470	COG3723	Recombinational DNA repair protein, rece pathway
GII86_RS13475	COG5377	YqaJ viral recombinase family
GII86_RS13505	COG1476	TRANSCRIPTIONal
GII86_RS13510	COG3620	sequence-specific DNA binding
GII86_RS13520	COG0563	adenylate kinase activity
GII86_RS13525	COG2856	Zn peptidase
GII86_RS13545	COG0114	fumarate hydratase activity
GII86_RS13550	COG0583	DNA-binding transcription factor activity
GII86_RS13560	COG0457	Tetratricopeptide repeat
GII86_RS13675	COG4978	Transcriptional regulator
GII86_RS13675	COG0789	Transcriptional regulator
GII86_RS13680	COG2814	Major facilitator Superfamily
GII86_RS13685	COG0456	acetyltransferase
GII86_RS13690	COG1253	flavin adenine dinucleotide binding
GII86_RS13700	COG0697	spore germination
GII86_RS13705	COG0583	DNA-binding transcription factor activity
GII86_RS13710	COG2072	flavoprotein involved in K transport
GII86_RS13715	COG1230	cation diffusion facilitator family transporter
GII86_RS13725	COG1114	Component of the transport system for branched-chain amino acids
GII86_RS13730	COG1687	branched-chain amino acid
GII86_RS13735	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GII86_RS13740	COG1522	sequence-specific DNA binding
GII86_RS13745	COG2732	(Barnase) inhibitor
GII86_RS13750	COG2124	cytochrome p450
GII86_RS13760	COG1335	isochorismatase
GII86_RS13775	COG2318	DinB family
GII86_RS13785	COG2070	2-Nitropropane dioxygenase
GII86_RS13790	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GII86_RS13810	COG3443	Belongs to the bacterial solute-binding protein 9 family
GII86_RS13815	COG1595	DNA-templated transcription, initiation
GII86_RS13820	COG0667	Aldo Keto reductase
GII86_RS13825	COG3409	Peptidoglycan-binding domain 1 protein
GII86_RS13830	COG5566	PFAM Mor transcription activator
GII86_RS13835	COG0596	Alpha beta hydrolase
GII86_RS13840	COG4991	sh3 domain protein
GII86_RS13845	COG4991	sh3 domain protein
GII86_RS13855	COG0346	lactoylglutathione lyase activity
GII86_RS13865	COG5577	PFAM Coat F domain
GII86_RS13870	COG1063	alcohol dehydrogenase
GII86_RS13880	COG5577	PFAM Coat F domain
GII86_RS13885	COG0789	Transcriptional regulator
GII86_RS13895	COG1064	alcohol dehydrogenase
GII86_RS13900	COG0693	protein deglycase activity
GII86_RS13905	COG1621	beta-fructofuranosidase activity
GII86_RS13910	COG3716	PTS system mannose fructose sorbose family IID component
GII86_RS13915	COG3715	PTS system
GII86_RS13920	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII86_RS13925	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII86_RS13930	COG3933	PFAM sigma-54 factor interaction domain-containing protein
GII86_RS13930	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GII86_RS13940	COG1113	amino acid transport
GII86_RS13945	COG1280	lysine exporter protein (LysE YggA)
GII86_RS13950	COG1378	Sugar-specific transcriptional regulator TrmB
GII86_RS13955	COG1595	DNA-templated transcription, initiation
GII86_RS13965	COG2755	lipolytic protein G-D-S-L family
GII86_RS13965	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GII86_RS13975	COG2124	cytochrome p450
GII86_RS13975	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GII86_RS13980	COG1309	transcriptional regulator
GII86_RS13985	COG2226	methyltransferase
GII86_RS14000	COG2116	formate transmembrane transporter activity
GII86_RS14005	COG5609	conserved protein (DUF2294)
GII86_RS14010	COG3383	formate dehydrogenase (NAD+) activity
GII86_RS14015	COG2427	Protein of unknown function (DUF1641)
GII86_RS14025	COG0626	cystathionine gamma-synthase activity
GII86_RS14030	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GII86_RS14035	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GII86_RS14040	COG2226	methyltransferase
GII86_RS14055	COG0768	penicillin binding
GII86_RS14060	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GII86_RS14075	COG5444	nuclease activity
GII86_RS14090	COG1388	LysM domain
GII86_RS14090	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII86_RS14090	COG3409	Peptidoglycan-binding domain 1 protein
GII86_RS14125	COG1705	Flagellar rod assembly protein muramidase FlgJ
GII86_RS14135	COG3953	SLT domain
GII86_RS14135	COG5280	Phage tail tape measure protein TP901
GII86_RS14230	COG0582	viral genome integration into host DNA
GII86_RS14320	COG1396	sequence-specific DNA binding
GII86_RS14340	COG0572	uridine kinase
GII86_RS14345	COG0826	peptidase U32
GII86_RS14350	COG0826	peptidase U32
GII86_RS14355	COG4122	O-methyltransferase activity
GII86_RS14360	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GII86_RS14365	COG3906	Belongs to the UPF0473 family
GII86_RS14370	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GII86_RS14375	COG4472	Bacterial protein of unknown function (DUF965)
GII86_RS14380	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GII86_RS14385	COG0628	permease
GII86_RS14390	COG1126	abc transporter atp-binding protein
GII86_RS14395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII86_RS14400	COG0765	amino acid transport
GII86_RS14405	COG0765	amino acid transport
GII86_RS14420	COG3881	PFAM PRC-barrel domain
GII86_RS14425	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GII86_RS14430	COG0457	Tetratricopeptide repeat
GII86_RS14435	COG0482	sulfurtransferase activity
GII86_RS14440	COG1104	cysteine desulfurase activity
GII86_RS14445	COG1959	2 iron, 2 sulfur cluster binding
GII86_RS14450	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GII86_RS14455	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GII86_RS14465	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GII86_RS14470	COG0124	histidyl-tRNA synthetase
GII86_RS14480	COG4991	sh3 domain protein
GII86_RS14480	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII86_RS14480	COG3103	Sh3 type 3 domain protein
GII86_RS14485	COG1490	D-aminoacyl-tRNA deacylase activity
GII86_RS14490	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GII86_RS14495	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GII86_RS14500	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GII86_RS14500	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GII86_RS14505	COG5416	Lipopolysaccharide assembly protein A domain
GII86_RS14510	COG0490	domain, Protein
GII86_RS14515	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GII86_RS14515	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GII86_RS14525	COG2244	polysaccharide biosynthetic process
GII86_RS14530	COG2323	membrane
GII86_RS14540	COG1862	Preprotein translocase
GII86_RS14545	COG0343	queuine tRNA-ribosyltransferase activity
GII86_RS14550	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GII86_RS14560	COG2255	four-way junction helicase activity
GII86_RS14565	COG0632	four-way junction helicase activity
GII86_RS14575	COG2814	Major facilitator Superfamily
GII86_RS14580	COG0673	inositol 2-dehydrogenase activity
GII86_RS14585	COG2112	serine threonine protein kinase
GII86_RS14605	COG1115	amino acid carrier protein
GII86_RS14610	COG0217	transcriptional regulatory protein
GII86_RS14620	COG1388	LysM domain
GII86_RS14625	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GII86_RS14630	COG0157	Belongs to the NadC ModD family
GII86_RS14635	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GII86_RS14640	COG1104	cysteine desulfurase activity
GII86_RS14645	COG1827	regulation of RNA biosynthetic process
GII86_RS14650	COG0077	Prephenate dehydratase
GII86_RS14655	COG4492	Belongs to the UPF0735 family
GII86_RS14660	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GII86_RS14665	COG3290	protein histidine kinase activity
GII86_RS14675	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GII86_RS14680	COG2868	ribosomal protein
GII86_RS14685	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GII86_RS14690	COG1994	Peptidase M50
GII86_RS14695	COG0739	heme binding
GII86_RS14700	COG2894	cell division
GII86_RS14705	COG0850	regulation of cytokinetic process
GII86_RS14710	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GII86_RS14720	COG1077	Cell shape determining protein MreB Mrl
GII86_RS14735	COG3409	Peptidoglycan-binding domain 1 protein
GII86_RS14735	COG5632	N-Acetylmuramoyl-L-alanine amidase
GII86_RS14740	COG4824	toxin secretion phage lysis holin
GII86_RS14775	COG3953	SLT domain
GII86_RS14775	COG5412	phage tail tape measure protein
GII86_RS14895	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GII86_RS14895	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GII86_RS14935	COG1396	sequence-specific DNA binding
GII86_RS14950	COG2003	Belongs to the UPF0758 family
GII86_RS14955	COG0424	maF-like protein
GII86_RS14965	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GII86_RS14970	COG0285	dihydrofolate synthase activity
GII86_RS14975	COG0525	valine-tRNA ligase activity
GII86_RS14985	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII86_RS14990	COG1388	LysM domain
GII86_RS14995	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GII86_RS15000	COG0113	porphobilinogen synthase activity
GII86_RS15005	COG1587	Uroporphyrinogen-III synthase
GII86_RS15010	COG0181	hydroxymethylbilane synthase activity
GII86_RS15015	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GII86_RS15020	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GII86_RS15030	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GII86_RS15035	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GII86_RS15040	COG1067	ATP-dependent peptidase activity
GII86_RS15040	COG0470	DNA polymerase III
GII86_RS15045	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GII86_RS15050	COG0544	peptidyl-prolyl cis-trans isomerase activity
GII86_RS15055	COG1477	protein flavinylation
GII86_RS15055	COG0457	Tetratricopeptide repeat
GII86_RS15060	COG0066	3-isopropylmalate dehydratase activity
GII86_RS15065	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GII86_RS15070	COG0473	3-isopropylmalate dehydrogenase activity
GII86_RS15075	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GII86_RS15080	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GII86_RS15085	COG0440	acetolactate synthase activity
GII86_RS15090	COG0028	Belongs to the TPP enzyme family
GII86_RS15100	COG0454	-acetyltransferase
GII86_RS15105	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
GII86_RS15115	COG0622	Phosphoesterase
GII86_RS15120	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GII86_RS15125	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GII86_RS15130	COG5401	PFAM Sporulation and spore germination
GII86_RS15135	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GII86_RS15140	COG1846	Transcriptional regulator
GII86_RS15145	COG2197	response regulator
GII86_RS15150	COG0824	Thioesterase
GII86_RS15155	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GII86_RS15160	COG1053	succinate dehydrogenase
GII86_RS15165	COG2009	succinate dehydrogenase
GII86_RS15170	COG1719	4-vinyl reductase, 4VR
GII86_RS15175	COG0527	aspartate kinase activity
GII86_RS15180	COG0322	excinuclease ABC activity
GII86_RS15185	COG3118	belongs to the thioredoxin family
GII86_RS15190	COG3534	alpha-L-arabinofuranosidase
GII86_RS15195	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GII86_RS15200	COG2086	electron transfer activity
GII86_RS15205	COG1024	Enoyl-CoA hydratase
GII86_RS15210	COG1309	transcriptional regulator
GII86_RS15215	COG0318	PFAM AMP-dependent synthetase and ligase
GII86_RS15220	COG3766	membrane
GII86_RS15225	COG1193	negative regulation of DNA recombination
GII86_RS15230	COG1796	DNA polymerase
GII86_RS15230	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GII86_RS15235	COG1286	toxin biosynthetic process
GII86_RS15240	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GII86_RS15245	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GII86_RS15250	COG0072	phenylalanine-tRNA ligase activity
GII86_RS15250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII86_RS15255	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GII86_RS15265	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GII86_RS15275	COG3835	regulator
GII86_RS15280	COG0277	FAD linked oxidase domain protein
GII86_RS15285	COG0247	lactate metabolic process
GII86_RS15290	COG0346	lactoylglutathione lyase activity
GII86_RS15300	COG1966	Carbon starvation protein
GII86_RS15305	COG3534	alpha-L-arabinofuranosidase
GII86_RS15310	COG0395	ABC-type sugar transport system, permease component
GII86_RS15315	COG1175	transmembrane transport
GII86_RS15320	COG1653	transport
GII86_RS15325	COG0371	Dehydrogenase
GII86_RS15330	COG0647	UMP catabolic process
GII86_RS15335	COG0235	Class ii aldolase
GII86_RS15340	COG1069	ribulokinase activity
GII86_RS15345	COG2160	L-arabinose isomerase activity
GII86_RS15350	COG3507	Belongs to the glycosyl hydrolase 43 family
GII86_RS15355	COG1363	Peptidase, m42
GII86_RS15365	COG3326	Membrane
GII86_RS15370	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GII86_RS15375	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GII86_RS15380	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GII86_RS15390	COG1346	cytolysis
GII86_RS15395	COG1380	Effector of murein hydrolase LrgA
GII86_RS15400	COG3279	Response regulator of the LytR AlgR family
GII86_RS15405	COG3275	phosphorelay sensor kinase activity
GII86_RS15410	COG1011	Hydrolase
GII86_RS15415	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GII86_RS15425	COG0398	Pfam SNARE associated Golgi protein
GII86_RS15430	COG1484	DNA-dependent DNA replication
GII86_RS15435	COG3611	Membrane attachment protein
GII86_RS15440	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GII86_RS15445	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GII86_RS15450	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GII86_RS15455	COG1733	regulation of RNA biosynthetic process
GII86_RS15460	COG2814	Major facilitator Superfamily
GII86_RS15465	COG0656	L-ascorbic acid biosynthetic process
GII86_RS15470	COG0237	dephospho-CoA kinase activity
GII86_RS15475	COG1971	Probably functions as a manganese efflux pump
GII86_RS15480	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GII86_RS15485	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GII86_RS15485	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GII86_RS15490	COG5002	protein histidine kinase activity
GII86_RS15495	COG0745	RESPONSE REGULATOR receiver
GII86_RS15500	COG0039	L-malate dehydrogenase activity
GII86_RS15505	COG0538	isocitrate dehydrogenase activity
GII86_RS15510	COG0372	Belongs to the citrate synthase family
GII86_RS15515	COG2707	UPF0756 membrane protein
GII86_RS15520	COG0628	permease
GII86_RS15525	COG3030	protein affecting phage T7 exclusion by the F plasmid
GII86_RS15530	COG0469	pyruvate kinase activity
GII86_RS15535	COG0205	6-phosphofructokinase activity
GII86_RS15540	COG0825	malonyl-CoA metabolic process
GII86_RS15545	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GII86_RS15550	COG0281	malic enzyme
GII86_RS15555	COG0587	DNA-directed DNA polymerase activity
GII86_RS15575	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GII86_RS15585	COG4109	DRTGG domain
GII86_RS15590	COG0730	response to heat
GII86_RS15595	COG1473	amidohydrolase
GII86_RS15600	COG0196	riboflavin kinase activity
GII86_RS15605	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII86_RS15610	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GII86_RS15615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII86_RS15620	COG1126	abc transporter atp-binding protein
GII86_RS15625	COG0765	amino acid transport
GII86_RS15630	COG0765	amino acid transport
GII86_RS15635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII86_RS15640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII86_RS15645	COG0454	-acetyltransferase
GII86_RS15650	COG0583	DNA-binding transcription factor activity
GII86_RS15655	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GII86_RS15660	COG1028	Short-chain dehydrogenase reductase Sdr
GII86_RS15670	COG0165	Argininosuccinate lyase
GII86_RS15675	COG0137	argininosuccinate synthase activity
GII86_RS15680	COG0521	Mo-molybdopterin cofactor biosynthetic process
GII86_RS15685	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GII86_RS15695	COG0827	DNA restriction-modification system
GII86_RS15700	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GII86_RS15705	COG3874	Sporulation protein YtfJ
GII86_RS15715	COG1714	RDD family
GII86_RS15720	COG0616	signal peptide processing
GII86_RS15725	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GII86_RS15730	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GII86_RS15735	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GII86_RS15745	COG0301	tRNA thio-modification
GII86_RS15750	COG1104	cysteine desulfurase activity
GII86_RS15755	COG1114	Component of the transport system for branched-chain amino acids
GII86_RS15760	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GII86_RS15765	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GII86_RS15770	COG1309	transcriptional regulator
GII86_RS15775	COG1956	GAF domain-containing protein
GII86_RS15780	COG2199	diguanylate cyclase activity
GII86_RS15780	COG2203	Gaf domain
GII86_RS15790	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GII86_RS15795	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GII86_RS15800	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GII86_RS15805	COG0454	-acetyltransferase
GII86_RS15810	COG0517	IMP dehydrogenase activity
GII86_RS15815	COG0123	including yeast histone deacetylase and acetoin utilization protein
GII86_RS15820	COG1360	Flagellar Motor Protein
GII86_RS15825	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GII86_RS15830	COG1609	Transcriptional regulator
GII86_RS15835	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GII86_RS15835	COG1605	Chorismate mutase
GII86_RS15840	COG3118	belongs to the thioredoxin family
GII86_RS15845	COG4980	gas vesicle protein
GII86_RS15850	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GII86_RS15855	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GII86_RS15860	COG1674	ftsk spoiiie
GII86_RS15865	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GII86_RS15870	COG4848	Belongs to the UPF0354 family
GII86_RS15875	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII86_RS15890	COG1363	Peptidase, m42
GII86_RS15895	COG5584	Small secreted protein
GII86_RS15900	COG0281	malic enzyme
GII86_RS15905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII86_RS15910	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GII86_RS15920	COG0510	thiamine kinase activity
GII86_RS15925	COG1523	belongs to the glycosyl hydrolase 13 family
GII86_RS15930	COG1597	lipid kinase activity
GII86_RS15940	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GII86_RS15945	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GII86_RS15950	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII86_RS15955	COG2252	PERMEase
GII86_RS15960	COG4473	ABC transporter
GII86_RS15965	COG1131	(ABC) transporter
GII86_RS15970	COG1349	DNA-binding transcription factor activity
GII86_RS15975	COG1187	pseudouridine synthase activity
GII86_RS15980	COG2244	polysaccharide biosynthetic process
GII86_RS15985	COG2081	HI0933 family
GII86_RS15990	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GII86_RS16000	COG5578	integral membrane protein
GII86_RS16005	COG0673	inositol 2-dehydrogenase activity
GII86_RS16010	COG1653	transport
GII86_RS16015	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GII86_RS16020	COG4209	transmembrane transport
GII86_RS16025	COG2207	Transcriptional regulator
GII86_RS16030	COG1653	transport
GII86_RS16035	COG0395	ABC-type sugar transport system, permease component
GII86_RS16040	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII86_RS16045	COG2124	cytochrome p450
GII86_RS16050	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GII86_RS16060	COG0156	8-amino-7-oxononanoate synthase activity
GII86_RS16065	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GII86_RS16075	COG1073	alpha beta
GII86_RS16080	COG1609	Transcriptional regulator
GII86_RS16085	COG1653	transport
GII86_RS16090	COG1175	transmembrane transport
GII86_RS16095	COG0395	ABC-type sugar transport system, permease component
GII86_RS16100	COG1486	melibiose metabolic process
GII86_RS16105	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GII86_RS16110	COG0495	leucyl-tRNA aminoacylation
GII86_RS16120	COG2202	Pas domain
GII86_RS16120	COG1366	Belongs to the anti-sigma-factor antagonist family
GII86_RS16125	COG2814	Major facilitator Superfamily
GII86_RS16135	COG0577	efflux transmembrane transporter activity
GII86_RS16140	COG1136	(ABC) transporter
GII86_RS16145	COG2205	protein histidine kinase activity
GII86_RS16150	COG0745	RESPONSE REGULATOR receiver
GII86_RS16155	COG0577	efflux transmembrane transporter activity
GII86_RS16160	COG1136	(ABC) transporter
GII86_RS16175	COG1131	(ABC) transporter
GII86_RS16180	COG1725	Transcriptional regulator
GII86_RS16195	COG1242	4 iron, 4 sulfur cluster binding
GII86_RS16200	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GII86_RS16210	COG2267	carboxylic ester hydrolase activity
GII86_RS16215	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GII86_RS16220	COG1113	amino acid transport
GII86_RS16225	COG0367	asparagine synthase
GII86_RS16230	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GII86_RS16235	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GII86_RS16245	COG1506	peptidase
GII86_RS16250	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GII86_RS16255	COG1116	anion transmembrane transporter activity
GII86_RS16260	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GII86_RS16265	COG0494	nUDIX hydrolase
GII86_RS16270	COG4824	toxin secretion phage lysis holin
GII86_RS16275	COG0783	Belongs to the Dps family
GII86_RS16290	COG1854	S-ribosylhomocysteine lyase activity
GII86_RS16295	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GII86_RS16300	COG0288	reversible hydration of carbon dioxide
GII86_RS16305	COG0254	rRNA binding
GII86_RS16310	COG1271	oxidase subunit
GII86_RS16315	COG1294	oxidase, subunit
GII86_RS16325	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GII86_RS16330	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GII86_RS16330	COG1321	iron dependent repressor
GII86_RS16335	COG1121	(ABC) transporter
GII86_RS16340	COG0803	Belongs to the bacterial solute-binding protein 9 family
GII86_RS16345	COG4948	Mandelate Racemase Muconate Lactonizing
GII86_RS16350	COG0318	PFAM AMP-dependent synthetase and ligase
GII86_RS16355	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GII86_RS16360	COG0596	Alpha beta hydrolase
GII86_RS16365	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GII86_RS16370	COG1169	isochorismate synthase
GII86_RS16375	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GII86_RS16380	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GII86_RS16385	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GII86_RS16390	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GII86_RS16395	COG0438	transferase activity, transferring glycosyl groups
GII86_RS16405	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII86_RS16410	COG0438	transferase activity, transferring glycosyl groups
GII86_RS16415	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII86_RS16420	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
GII86_RS16425	COG0058	SHG alpha-glucan phosphorylase activity
GII86_RS16430	COG0297	glycogen (starch) synthase activity
GII86_RS16435	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GII86_RS16440	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GII86_RS16445	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GII86_RS16570	COG3859	Proton-coupled thiamine transporter YuaJ
GII86_RS16575	COG1247	-acetyltransferase
GII86_RS16580	COG2268	Band 7 protein
GII86_RS16585	COG1585	Membrane protein implicated in regulation of membrane protease activity
GII86_RS16590	COG2318	DinB family
GII86_RS16600	COG1454	alcohol dehydrogenase
GII86_RS16605	COG1012	belongs to the aldehyde dehydrogenase family
GII86_RS16610	COG1510	regulation of RNA biosynthetic process
GII86_RS16620	COG0569	domain protein
GII86_RS16625	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GII86_RS16630	COG4682	membrane
GII86_RS16635	COG1705	Flagellar rod assembly protein muramidase FlgJ
GII86_RS16640	COG0477	Major facilitator Superfamily
GII86_RS16645	COG5553	Cysteine dioxygenase type I
GII86_RS16655	COG1968	undecaprenyl-diphosphatase activity
GII86_RS16660	COG0628	permease
GII86_RS16665	COG0673	inositol 2-dehydrogenase activity
GII86_RS16670	COG4806	L-rhamnose isomerase
GII86_RS16675	COG3254	rhamnose metabolic process
GII86_RS16680	COG1070	Carbohydrate kinase
GII86_RS16685	COG1349	DNA-binding transcription factor activity
GII86_RS16690	COG3347	Dehydrogenase
GII86_RS16690	COG1028	Short-chain dehydrogenase reductase Sdr
GII86_RS16695	COG0840	transmembrane signaling receptor activity
GII86_RS16700	COG0840	transmembrane signaling receptor activity
GII86_RS16705	COG0840	transmembrane signaling receptor activity
GII86_RS16710	COG0840	transmembrane signaling receptor activity
GII86_RS16725	COG0432	Pfam Uncharacterised protein family UPF0047
GII86_RS16735	COG0366	Alpha amylase catalytic
GII86_RS16740	COG1253	flavin adenine dinucleotide binding
GII86_RS16745	COG2738	Putative neutral zinc metallopeptidase
GII86_RS16760	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GII86_RS16775	COG0166	Belongs to the GPI family
GII86_RS16780	COG1979	alcohol dehydrogenase
GII86_RS16785	COG1979	alcohol dehydrogenase
GII86_RS16790	COG2155	Conserved Protein
GII86_RS16795	COG1098	S1 RNA binding domain
GII86_RS16800	COG0436	Aminotransferase
GII86_RS16805	COG1522	sequence-specific DNA binding
GII86_RS16810	COG2267	carboxylic ester hydrolase activity
GII86_RS16820	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GII86_RS16825	COG2205	protein histidine kinase activity
GII86_RS16835	COG5018	Exonuclease
GII86_RS16845	COG2814	Major facilitator Superfamily
GII86_RS16850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII86_RS16855	COG3011	Protein conserved in bacteria
GII86_RS16865	COG3290	protein histidine kinase activity
GII86_RS16870	COG4565	transcriptional regulatory protein
GII86_RS16875	COG1744	ABC transporter substrate-binding protein PnrA-like
GII86_RS16880	COG3845	ABC transporter
GII86_RS16885	COG4603	Belongs to the binding-protein-dependent transport system permease family
GII86_RS16890	COG1079	Belongs to the binding-protein-dependent transport system permease family
GII86_RS16895	COG3493	citrate carrier protein
GII86_RS16905	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GII86_RS16905	COG2111	Na H antiporter
GII86_RS16910	COG2111	Na H antiporter
GII86_RS16915	COG1006	Multisubunit Na H antiporter MnhC subunit
GII86_RS16920	COG0651	ATP synthesis coupled electron transport
GII86_RS16925	COG1863	multisubunit Na H antiporter MnhE subunit
GII86_RS16930	COG2212	antiporter activity
GII86_RS16935	COG1320	monovalent cation:proton antiporter activity
GII86_RS16940	COG2050	protein possibly involved in aromatic compounds catabolism
GII86_RS16945	COG2197	response regulator
GII86_RS16950	COG4585	Histidine kinase
GII86_RS16960	COG0142	geranyltranstransferase activity
GII86_RS16980	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GII86_RS16985	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GII86_RS16990	COG1335	isochorismatase
GII86_RS16995	COG5506	Protein of unknown function (DUF1694)
GII86_RS17010	COG0628	permease
GII86_RS17025	COG1418	mRNA catabolic process
GII86_RS17030	COG1028	Short-chain dehydrogenase reductase Sdr
GII86_RS17040	COG1511	domain protein
GII86_RS17045	COG0433	COG0433 Predicted ATPase
GII86_RS17045	COG1674	ftsk spoiiie
GII86_RS17050	COG4499	WXG100 protein secretion system (Wss), protein YukC
GII86_RS17055	COG5417	Belongs to the EsaB family
GII86_RS17060	COG4842	Belongs to the WXG100 family
GII86_RS17065	COG2508	Transcriptional regulator
GII86_RS17065	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GII86_RS17070	COG0686	Belongs to the AlaDH PNT family
GII86_RS17075	COG5634	Uncharacterized conserved protein (DUF2278)
GII86_RS17080	COG3251	PFAM MbtH domain protein
GII86_RS17085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII86_RS17090	COG3433	isochorismatase activity
GII86_RS17090	COG1535	isochorismatase
GII86_RS17095	COG1021	2,3-dihydroxybenzoate-AMP ligase
GII86_RS17100	COG1169	isochorismate synthase
GII86_RS17105	COG1028	Short-chain dehydrogenase reductase Sdr
GII86_RS17110	COG2819	hydrolase of the alpha beta superfamily
GII86_RS17115	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GII86_RS17120	COG1268	BioY protein
GII86_RS17125	COG2056	Na+-H+ antiporter family
GII86_RS17130	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GII86_RS17135	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
GII86_RS17140	COG3584	3D domain protein
GII86_RS17155	COG1252	NADH dehydrogenase
GII86_RS17160	COG0492	ferredoxin-NADP+ reductase activity
GII86_RS17170	COG0516	GMP reductase activity
GII86_RS17175	COG2808	Putative FMN-binding domain
GII86_RS17180	COG0456	acetyltransferase
GII86_RS17185	COG0316	Belongs to the HesB IscA family
GII86_RS17190	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GII86_RS17195	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GII86_RS17200	COG4844	belongs to the
GII86_RS17205	COG1252	NADH dehydrogenase
GII86_RS17210	COG4837	Protein of unknown function (DUF1462)
GII86_RS17215	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GII86_RS17220	COG0823	Involved in the tonB-independent uptake of proteins
GII86_RS17220	COG1506	peptidase
GII86_RS17220	COG4946	Tricorn protease homolog
GII86_RS17225	COG0083	homoserine kinase activity
GII86_RS17230	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GII86_RS17235	COG0460	homoserine dehydrogenase
GII86_RS17240	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GII86_RS17245	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GII86_RS17250	COG0647	UMP catabolic process
GII86_RS17255	COG2445	Protein of unknown function DUF86
GII86_RS17260	COG4470	Protein conserved in bacteria
GII86_RS17270	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GII86_RS17275	COG0739	heme binding
GII86_RS17285	COG3377	Domain of unknown function (DUF1805)
GII86_RS17290	COG0737	Belongs to the 5'-nucleotidase family
GII86_RS17295	COG0730	response to heat
GII86_RS17300	COG1801	Protein of unknown function DUF72
GII86_RS17310	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GII86_RS17315	COG2508	Transcriptional regulator
GII86_RS17320	COG2233	PERMEase
GII86_RS17325	COG2233	PERMEase
GII86_RS17330	COG3195	allantoin biosynthetic process
GII86_RS17330	COG3648	Uricase
GII86_RS17335	COG2351	hydroxyisourate hydrolase activity
GII86_RS17345	COG2080	2 iron, 2 sulfur cluster binding
GII86_RS17350	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GII86_RS17355	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GII86_RS17360	COG2068	MobA-Related Protein
GII86_RS17365	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GII86_RS17370	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GII86_RS17375	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GII86_RS17385	COG2356	endonuclease I
GII86_RS17390	COG3842	ATPase activity
GII86_RS17395	COG2188	Transcriptional regulator
GII86_RS17400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII86_RS17405	COG0395	ABC-type sugar transport system, permease component
GII86_RS17410	COG1175	transmembrane transport
GII86_RS17415	COG1653	transport
GII86_RS17420	COG2222	sugar isomerase
GII86_RS17425	COG0322	excinuclease ABC activity
GII86_RS17430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GII86_RS17445	COG0346	lactoylglutathione lyase activity
GII86_RS17450	COG0640	Transcriptional regulator
GII86_RS17455	COG0719	Fe-S assembly protein
GII86_RS17460	COG0822	iron-sulfur transferase activity
GII86_RS17465	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GII86_RS17470	COG0719	Fe-S assembly protein
GII86_RS17475	COG0396	ATPase activity
GII86_RS17485	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GII86_RS17490	COG1464	Belongs to the NlpA lipoprotein family
GII86_RS17495	COG2011	ABC-type metal ion transport system permease component
GII86_RS17500	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GII86_RS17510	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GII86_RS17515	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GII86_RS17525	COG0509	glycine decarboxylation via glycine cleavage system
GII86_RS17530	COG1393	Belongs to the ArsC family
GII86_RS17535	COG1960	acyl-CoA dehydrogenase activity
GII86_RS17540	COG0183	Belongs to the thiolase family
GII86_RS17545	COG1024	Enoyl-CoA hydratase
GII86_RS17545	COG1250	3-hydroxyacyl-CoA dehydrogenase
GII86_RS17555	COG0506	proline dehydrogenase activity
GII86_RS17565	COG5577	PFAM Coat F domain
GII86_RS17570	COG1846	Transcriptional regulator
GII86_RS17575	COG0477	Major facilitator Superfamily
GII86_RS17580	COG1942	4-Oxalocrotonate Tautomerase
GII86_RS17585	COG1028	Short-chain dehydrogenase reductase Sdr
GII86_RS17590	COG0583	DNA-binding transcription factor activity
GII86_RS17600	COG1120	ATPase activity
GII86_RS17615	COG1028	Short-chain dehydrogenase reductase Sdr
GII86_RS17620	COG0783	Belongs to the Dps family
GII86_RS17625	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII86_RS17630	COG0745	RESPONSE REGULATOR receiver
GII86_RS17635	COG2770	Histidine kinase
GII86_RS17635	COG2205	protein histidine kinase activity
GII86_RS17645	COG1309	transcriptional regulator
GII86_RS17650	COG0114	fumarate hydratase activity
GII86_RS17660	COG0697	spore germination
GII86_RS17665	COG0814	amino acid
GII86_RS17675	COG2197	response regulator
GII86_RS17680	COG4585	Histidine kinase
GII86_RS17685	COG4758	membrane
GII86_RS17690	COG3595	metallopeptidase activity
GII86_RS17695	COG1842	Phage shock protein A
GII86_RS17700	COG4758	membrane
GII86_RS17705	COG2814	Major facilitator Superfamily
GII86_RS17710	COG2096	Adenosyltransferase
GII86_RS17715	COG1120	ATPase activity
GII86_RS17720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII86_RS17725	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII86_RS17730	COG1028	Short-chain dehydrogenase reductase Sdr
GII86_RS17735	COG3386	PFAM SMP-30 Gluconolaconase
GII86_RS17740	COG2205	protein histidine kinase activity
GII86_RS17745	COG0745	RESPONSE REGULATOR receiver
GII86_RS17755	COG1191	sigma factor activity
GII86_RS17765	COG2140	Oxalate decarboxylase
GII86_RS17775	COG0577	efflux transmembrane transporter activity
GII86_RS17780	COG1136	(ABC) transporter
GII86_RS17785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GII86_RS17790	COG1120	ATPase activity
GII86_RS17795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII86_RS17800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GII86_RS17805	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII86_RS17810	COG0531	amino acid
GII86_RS17820	COG1988	membrane-bound metal-dependent
GII86_RS17825	COG1368	sulfuric ester hydrolase activity
GII86_RS17830	COG1910	domain protein
GII86_RS17835	COG0725	ABC transporter, periplasmic molybdate-binding protein
GII86_RS17840	COG4149	molybdate abc transporter
GII86_RS17845	COG0656	L-ascorbic acid biosynthetic process
GII86_RS17855	COG0025	NhaP-type Na H and K H
GII86_RS17860	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GII86_RS17865	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GII86_RS17870	COG3973	AAA domain
GII86_RS17880	COG2860	membrane
GII86_RS17885	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GII86_RS17890	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GII86_RS17895	COG2217	Heavy metal translocating P-type atpase
GII86_RS17900	COG2217	Heavy metal translocating P-type atpase
GII86_RS17905	COG2608	mercury ion transmembrane transporter activity
GII86_RS17910	COG1937	Protein conserved in bacteria
GII86_RS17915	COG0673	inositol 2-dehydrogenase activity
GII86_RS17920	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GII86_RS17925	COG1289	transmembrane transporter activity
GII86_RS17935	COG2076	Multidrug Resistance protein
GII86_RS17940	COG1309	transcriptional regulator
GII86_RS17945	COG1028	Short-chain dehydrogenase reductase Sdr
GII86_RS17955	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GII86_RS17960	COG0557	exoribonuclease II activity
GII86_RS17965	COG1647	Serine aminopeptidase, S33
GII86_RS17970	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GII86_RS17975	COG0596	Alpha beta hydrolase
GII86_RS17980	COG1476	TRANSCRIPTIONal
GII86_RS17985	COG1396	sequence-specific DNA binding
GII86_RS17990	COG1396	sequence-specific DNA binding
GII86_RS17995	COG1733	regulation of RNA biosynthetic process
GII86_RS18000	COG0840	transmembrane signaling receptor activity
GII86_RS18005	COG1174	glycine betaine transport
GII86_RS18010	COG1732	Glycine betaine
GII86_RS18015	COG1174	glycine betaine transport
GII86_RS18020	COG1125	glycine betaine transport
GII86_RS18020	COG0517	IMP dehydrogenase activity
GII86_RS18025	COG1510	regulation of RNA biosynthetic process
GII86_RS18030	COG1174	glycine betaine transport
GII86_RS18035	COG1732	Glycine betaine
GII86_RS18040	COG1174	glycine betaine transport
GII86_RS18045	COG1125	glycine betaine transport
GII86_RS18045	COG0517	IMP dehydrogenase activity
GII86_RS18050	COG1510	regulation of RNA biosynthetic process
GII86_RS18055	COG2095	MarC family integral membrane protein
GII86_RS18065	COG3064	Membrane
GII86_RS18070	COG4640	response to antibiotic
GII86_RS18075	COG0456	acetyltransferase
GII86_RS18080	COG0148	phosphopyruvate hydratase activity
GII86_RS18085	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GII86_RS18090	COG0149	triose-phosphate isomerase activity
GII86_RS18095	COG0126	phosphoglycerate kinase activity
GII86_RS18100	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GII86_RS18105	COG2390	Transcriptional regulator
GII86_RS18110	COG2814	Major facilitator Superfamily
GII86_RS18115	COG1609	Transcriptional regulator
GII86_RS18120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII86_RS18125	COG0583	DNA-binding transcription factor activity
GII86_RS18130	COG0697	spore germination
GII86_RS18135	COG1113	amino acid transport
GII86_RS18140	COG3858	chitin binding
GII86_RS18145	COG1556	Lactate utilization protein
GII86_RS18150	COG1139	Iron-sulfur cluster binding protein
GII86_RS18155	COG0247	lactate metabolic process
GII86_RS18170	COG2197	response regulator
GII86_RS18175	COG4585	Histidine kinase
GII86_RS18180	COG0842	Transport permease protein
GII86_RS18185	COG1131	(ABC) transporter
GII86_RS18205	COG0596	Alpha beta hydrolase
GII86_RS18210	COG2208	phosphoserine phosphatase activity
GII86_RS18215	COG3867	Arabinogalactan endo-beta-1,4-galactanase
GII86_RS18220	COG1874	Beta-galactosidase
GII86_RS18225	COG3833	ABC-type maltose transport systems, permease component
GII86_RS18230	COG1175	transmembrane transport
GII86_RS18235	COG2182	Extracellular solute-binding protein
GII86_RS18240	COG1609	Transcriptional regulator
GII86_RS18245	COG2186	Transcriptional regulator
GII86_RS18250	COG1620	l-lactate permease
GII86_RS18255	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GII86_RS18265	COG5039	Polysaccharide pyruvyl transferase
GII86_RS18270	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GII86_RS18275	COG0110	maltose O-acetyltransferase activity
GII86_RS18280	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GII86_RS18285	COG2244	polysaccharide biosynthetic process
GII86_RS18290	COG1216	Glycosyl transferase, family 2
GII86_RS18295	COG5039	Polysaccharide pyruvyl transferase
GII86_RS18300	COG1216	Glycosyl transferase, family 2
GII86_RS18310	COG0438	transferase activity, transferring glycosyl groups
GII86_RS18315	COG1215	transferase activity, transferring glycosyl groups
GII86_RS18320	COG0438	transferase activity, transferring glycosyl groups
GII86_RS18325	COG1086	Polysaccharide biosynthesis protein
GII86_RS18330	COG0489	protein tyrosine kinase activity
GII86_RS18335	COG3944	biosynthesis protein
GII86_RS18340	COG1396	sequence-specific DNA binding
GII86_RS18345	COG2272	Belongs to the type-B carboxylesterase lipase family
GII86_RS18355	COG3479	Phenolic acid decarboxylase
GII86_RS18365	COG1794	racemase activity, acting on amino acids and derivatives
GII86_RS18370	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GII86_RS18375	COG1621	beta-fructofuranosidase activity
GII86_RS18380	COG1621	beta-fructofuranosidase activity
GII86_RS18385	COG0531	amino acid
GII86_RS18390	COG1309	transcriptional regulator
GII86_RS18395	COG2076	Multidrug Resistance protein
GII86_RS18400	COG2076	Multidrug Resistance protein
GII86_RS18415	COG0740	serine-type endopeptidase activity
GII86_RS18420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GII86_RS18425	COG0366	Alpha amylase catalytic
GII86_RS18430	COG1554	hydrolase, family 65, central catalytic
GII86_RS18435	COG5521	maltodextrose utilization protein MalA
GII86_RS18440	COG3833	ABC-type maltose transport systems, permease component
GII86_RS18445	COG1175	transmembrane transport
GII86_RS18450	COG2182	Extracellular solute-binding protein
GII86_RS18460	COG1609	Transcriptional regulator
GII86_RS18470	COG1694	Mazg nucleotide pyrophosphohydrolase
GII86_RS18475	COG0659	secondary active sulfate transmembrane transporter activity
GII86_RS18480	COG0288	reversible hydration of carbon dioxide
GII86_RS18485	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GII86_RS18490	COG0577	efflux transmembrane transporter activity
GII86_RS18495	COG1136	(ABC) transporter
GII86_RS18500	COG5002	protein histidine kinase activity
GII86_RS18505	COG0745	RESPONSE REGULATOR receiver
GII86_RS18515	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GII86_RS18520	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GII86_RS18525	COG1481	regulation of sporulation
GII86_RS18530	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GII86_RS18535	COG1660	Displays ATPase and GTPase activities
GII86_RS18540	COG1051	belongs to the nudix hydrolase family
GII86_RS18545	COG0492	ferredoxin-NADP+ reductase activity
GII86_RS18550	COG0791	NLP P60 protein
GII86_RS18550	COG3883	PFAM NLP P60 protein
GII86_RS18555	COG0457	Tetratricopeptide repeat
GII86_RS18560	COG1132	(ABC) transporter
GII86_RS18580	COG0140	phosphoribosyl-ATP diphosphatase activity
GII86_RS18580	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GII86_RS18585	COG0107	imidazoleglycerol-phosphate synthase activity
GII86_RS18590	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GII86_RS18595	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GII86_RS18600	COG0131	Imidazoleglycerol-phosphate dehydratase
GII86_RS18605	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GII86_RS18610	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GII86_RS18615	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GII86_RS18620	COG4990	cell redox homeostasis
GII86_RS18625	COG5297	Belongs to the glycosyl hydrolase family 6
GII86_RS18630	COG0110	maltose O-acetyltransferase activity
GII86_RS18635	COG0546	phosphoglycolate phosphatase activity
GII86_RS18640	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GII86_RS18645	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GII86_RS18650	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GII86_RS18655	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GII86_RS18660	COG0363	glucosamine-6-phosphate deaminase activity
GII86_RS18665	COG2188	Transcriptional regulator
GII86_RS18670	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GII86_RS18675	COG1846	Transcriptional regulator
GII86_RS18680	COG2124	cytochrome p450
GII86_RS18690	COG1846	Transcriptional regulator
GII86_RS18695	COG2814	Major facilitator Superfamily
GII86_RS18700	COG1950	PFAM Membrane protein of
GII86_RS18705	COG1983	PspC domain protein
GII86_RS18710	COG3595	metallopeptidase activity
GII86_RS18725	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GII86_RS18730	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GII86_RS18735	COG0556	nucleotide-excision repair
GII86_RS18740	COG4897	Protein conserved in bacteria
GII86_RS18745	COG0574	Belongs to the PEP-utilizing enzyme family
GII86_RS18745	COG3848	Pyruvate phosphate dikinase
GII86_RS18750	COG1309	transcriptional regulator
GII86_RS18755	COG2814	Major facilitator Superfamily
GII86_RS18760	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII86_RS18770	COG3409	Peptidoglycan-binding domain 1 protein
GII86_RS18770	COG0793	Belongs to the peptidase S41A family
GII86_RS18775	COG2177	Part of the ABC transporter FtsEX involved in
GII86_RS18780	COG2884	Cell division ATP-binding protein ftsE
GII86_RS18785	COG2010	Cytochrome c
GII86_RS18790	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII86_RS18800	COG0653	protein targeting
GII86_RS18805	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GII86_RS18820	COG1516	flagellar protein fliS
GII86_RS18825	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GII86_RS18830	COG1334	flagellar protein FlaG
GII86_RS18835	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GII86_RS18840	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GII86_RS18845	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
GII86_RS18855	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GII86_RS18860	COG4786	Flagellar basal body rod
GII86_RS18860	COG1256	bacterial-type flagellum assembly
GII86_RS18865	COG3418	PFAM FlgN family protein
GII86_RS18870	COG2747	anti-sigma28 factor FlgM
GII86_RS18880	COG1040	competence protein
GII86_RS18890	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GII86_RS18895	COG1307	EDD domain protein, DegV family
GII86_RS18900	COG2197	response regulator
GII86_RS18905	COG4585	Histidine kinase
GII86_RS18910	COG1739	Uncharacterized protein family UPF0029
GII86_RS18915	COG1316	TRANSCRIPTIONal
GII86_RS18945	COG1131	(ABC) transporter
GII86_RS18955	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GII86_RS18960	COG0438	transferase activity, transferring glycosyl groups
GII86_RS18965	COG1215	transferase activity, transferring glycosyl groups
GII86_RS18970	COG3206	protein involved in exopolysaccharide biosynthesis
GII86_RS18975	COG3307	-O-antigen
GII86_RS18980	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GII86_RS18985	COG0438	transferase activity, transferring glycosyl groups
GII86_RS18985	COG0297	glycogen (starch) synthase activity
GII86_RS18990	COG2244	polysaccharide biosynthetic process
GII86_RS19000	COG2247	cell wall binding repeat
GII86_RS19000	COG0860	N-Acetylmuramoyl-L-alanine amidase
GII86_RS19005	COG2385	sporulation resulting in formation of a cellular spore
GII86_RS19005	COG2247	cell wall binding repeat
GII86_RS19020	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GII86_RS19025	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GII86_RS19035	COG1134	teichoic acid transport
GII86_RS19040	COG1682	transport, permease protein
GII86_RS19055	COG0463	Glycosyl transferase, family 2
GII86_RS19055	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GII86_RS19060	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GII86_RS19065	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GII86_RS19070	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GII86_RS19075	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GII86_RS19080	COG4193	domain, Protein
GII86_RS19085	COG1482	cell wall glycoprotein biosynthetic process
GII86_RS19090	COG0697	spore germination
GII86_RS19095	COG0814	amino acid
GII86_RS19105	COG2814	Major facilitator Superfamily
GII86_RS19110	COG1316	TRANSCRIPTIONal
GII86_RS19115	COG0561	phosphatase activity
GII86_RS19120	COG0791	NLP P60 protein
GII86_RS19130	COG2843	Capsule synthesis protein
GII86_RS19140	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GII86_RS19145	COG1609	Transcriptional regulator
GII86_RS19150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII86_RS19155	COG1869	D-ribose catabolic process
GII86_RS19160	COG1129	ABC transporter
GII86_RS19165	COG1172	Belongs to the binding-protein-dependent transport system permease family
GII86_RS19170	COG1879	ABC-type sugar transport system periplasmic component
GII86_RS19175	COG3103	Sh3 type 3 domain protein
GII86_RS19185	COG2249	NAD(P)H dehydrogenase (quinone) activity
GII86_RS19190	COG3527	Alpha-acetolactate decarboxylase
GII86_RS19195	COG0028	Belongs to the TPP enzyme family
GII86_RS19200	COG0583	DNA-binding transcription factor activity
GII86_RS19205	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GII86_RS19220	COG5337	Spore coat protein CotH
GII86_RS19230	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GII86_RS19240	COG0405	Gamma-glutamyltransferase
GII86_RS19245	COG1522	sequence-specific DNA binding
GII86_RS19250	COG2059	Chromate
GII86_RS19255	COG2059	Chromate
GII86_RS19265	COG0655	NAD(P)H dehydrogenase (quinone) activity
GII86_RS19270	COG0583	DNA-binding transcription factor activity
GII86_RS19300	COG5444	nuclease activity
GII86_RS19320	COG3878	Protein conserved in bacteria
GII86_RS19325	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GII86_RS19330	COG4464	protein tyrosine phosphatase activity
GII86_RS19335	COG0489	protein tyrosine kinase activity
GII86_RS19340	COG3944	biosynthesis protein
GII86_RS19350	COG4715	Zinc finger, swim domain protein
GII86_RS19355	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GII86_RS19360	COG0561	phosphatase activity
GII86_RS19365	COG1349	DNA-binding transcription factor activity
GII86_RS19370	COG0629	single-stranded DNA binding
GII86_RS19385	COG3764	Sortase (surface protein transpeptidase)
GII86_RS19390	COG2972	Histidine kinase
GII86_RS19390	COG0745	RESPONSE REGULATOR receiver
GII86_RS19395	COG1970	mechanosensitive ion channel activity
GII86_RS19400	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GII86_RS19405	COG0457	Tetratricopeptide repeat
GII86_RS19410	COG4786	Flagellar basal body rod
GII86_RS19415	COG4786	Flagellar basal body rod
GII86_RS19420	COG1077	Cell shape determining protein MreB Mrl
GII86_RS19425	COG1609	Transcriptional regulator
GII86_RS19435	COG1846	Transcriptional regulator
GII86_RS19440	COG2814	Major facilitator Superfamily
GII86_RS19445	COG3420	alginic acid biosynthetic process
GII86_RS19450	COG1953	Uracil, thiamine, allantoin
GII86_RS19455	COG0477	Major facilitator Superfamily
GII86_RS19460	COG1335	isochorismatase
GII86_RS19470	COG0004	ammonium transporteR
GII86_RS19475	COG0347	Belongs to the P(II) protein family
GII86_RS19480	COG0671	phosphoesterase, PA-phosphatase related
GII86_RS19490	COG0739	heme binding
GII86_RS19495	COG1247	-acetyltransferase
GII86_RS19505	COG2089	acid synthase
GII86_RS19515	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GII86_RS19520	COG0789	Transcriptional regulator
GII86_RS19530	COG2910	NAD(P)H-binding
GII86_RS19535	COG1959	2 iron, 2 sulfur cluster binding
GII86_RS19540	COG0804	urea catabolic process
GII86_RS19545	COG0832	Belongs to the urease beta subunit family
GII86_RS19550	COG0831	urea catabolic process
GII86_RS19565	COG3237	CsbD-like
GII86_RS19570	COG1994	Peptidase M50
GII86_RS19575	COG0457	Tetratricopeptide repeat
GII86_RS19580	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GII86_RS19585	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GII86_RS19595	COG2304	oxidoreductase activity
GII86_RS19605	COG2304	oxidoreductase activity
GII86_RS19610	COG2385	sporulation resulting in formation of a cellular spore
GII86_RS19615	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GII86_RS19625	COG4836	Membrane
GII86_RS19635	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GII86_RS19640	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GII86_RS19645	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GII86_RS19650	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GII86_RS19655	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GII86_RS19660	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GII86_RS19670	COG0356	it plays a direct role in the translocation of protons across the membrane
GII86_RS19680	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GII86_RS19685	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GII86_RS19690	COG4475	Protein of unknown function (DUF436)
GII86_RS19695	COG0698	ribose 5-phosphate isomerase
GII86_RS19700	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GII86_RS19705	COG1971	Probably functions as a manganese efflux pump
GII86_RS19710	COG0009	L-threonylcarbamoyladenylate synthase
GII86_RS19715	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GII86_RS19735	COG2890	protein-(glutamine-N5) methyltransferase activity
GII86_RS19740	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GII86_RS19745	COG0346	lactoylglutathione lyase activity
GII86_RS19750	COG0789	Transcriptional regulator
GII86_RS19755	COG0679	Auxin Efflux Carrier
GII86_RS19760	COG0281	malic enzyme
GII86_RS19765	COG1435	thymidine kinase activity
GII86_RS19775	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GII86_RS19785	COG1494	fructose-1,6-bisphosphatase
GII86_RS19790	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GII86_RS19795	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GII86_RS19800	COG0191	fructose-bisphosphate aldolase activity
GII86_RS19805	COG2204	response regulator
GII86_RS19810	COG4821	SIS domain
GII86_RS19815	COG0504	CTP synthase activity
GII86_RS19820	COG3343	RNA polymerase activity
GII86_RS19825	COG1960	acyl-CoA dehydrogenase activity
GII86_RS19830	COG0247	lactate metabolic process
GII86_RS19830	COG2181	nitrate reductase activity
GII86_RS19835	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GII86_RS19840	COG4294	response to UV
GII86_RS19850	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GII86_RS19860	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GII86_RS19870	COG2181	nitrate reductase activity
GII86_RS19875	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GII86_RS19880	COG1140	nitrate reductase beta subunit
GII86_RS19885	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GII86_RS19890	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GII86_RS19900	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GII86_RS19905	COG2223	nitrite transmembrane transporter activity
GII86_RS19910	COG0018	arginyl-trna synthetase
GII86_RS19915	COG4506	Protein conserved in bacteria
GII86_RS19930	COG0535	radical SAM domain protein
GII86_RS19940	COG1131	(ABC) transporter
GII86_RS19945	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GII86_RS19950	COG0612	Peptidase, M16
GII86_RS19955	COG0612	Peptidase, M16
GII86_RS19965	COG3391	amine dehydrogenase activity
GII86_RS19970	COG3391	amine dehydrogenase activity
GII86_RS19980	COG0457	Tetratricopeptide repeat
GII86_RS19995	COG0010	Belongs to the arginase family
GII86_RS20000	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GII86_RS20005	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GII86_RS20020	COG1994	Peptidase M50
GII86_RS20025	COG1942	4-Oxalocrotonate Tautomerase
GII86_RS20030	COG1846	Transcriptional regulator
GII86_RS20035	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GII86_RS20040	COG0477	Major facilitator Superfamily
GII86_RS20045	COG1959	2 iron, 2 sulfur cluster binding
GII86_RS20050	COG3465	dGTPase activity
GII86_RS20055	COG1078	dGTPase activity
GII86_RS20060	COG4844	belongs to the
GII86_RS20070	COG0697	spore germination
GII86_RS20075	COG0095	Lipoate-protein ligase
GII86_RS20080	COG0583	DNA-binding transcription factor activity
GII86_RS20085	COG0280	phosphate acetyltransferase
GII86_RS20090	COG3253	May function as heme-dependent peroxidase
GII86_RS20095	COG1028	Short-chain dehydrogenase reductase Sdr
GII86_RS20100	COG0436	Aminotransferase
GII86_RS20105	COG2814	Major facilitator Superfamily
GII86_RS20110	COG0151	Belongs to the GarS family
GII86_RS20115	COG1028	Short-chain dehydrogenase reductase Sdr
GII86_RS20120	COG1917	Cupin 2, conserved barrel domain protein
GII86_RS20125	COG0077	Prephenate dehydratase
GII86_RS20130	COG2814	Major facilitator Superfamily
GII86_RS20135	COG0833	amino acid
GII86_RS20140	COG4187	Peptidase family M20/M25/M40
GII86_RS20145	COG1012	belongs to the aldehyde dehydrogenase family
GII86_RS20150	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GII86_RS20160	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
GII86_RS20165	COG1091	dTDP-4-dehydrorhamnose reductase activity
GII86_RS20170	COG1088	dTDP-glucose 4,6-dehydratase activity
GII86_RS20175	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GII86_RS20180	COG3980	spore coat polysaccharide biosynthesis protein
GII86_RS20185	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
GII86_RS20190	COG2089	acid synthase
GII86_RS20195	COG0456	acetyltransferase
GII86_RS20200	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GII86_RS20205	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GII86_RS20210	COG0463	Glycosyl transferase, family 2
GII86_RS20220	COG2363	Small membrane protein
GII86_RS20225	COG2233	PERMEase
GII86_RS20235	COG1012	belongs to the aldehyde dehydrogenase family
GII86_RS20240	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GII86_RS20245	COG1216	Glycosyl transferase, family 2
GII86_RS20250	COG0351	phosphomethylpyrimidine kinase
GII86_RS20260	COG1621	beta-fructofuranosidase activity
GII86_RS20265	COG1263	PTS System
GII86_RS20265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII86_RS20270	COG2116	formate transmembrane transporter activity
GII86_RS20275	COG3711	transcriptional antiterminator
GII86_RS20285	COG1404	Belongs to the peptidase S8 family
GII86_RS20290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII86_RS20295	COG0778	Nitroreductase
GII86_RS20300	COG0772	Belongs to the SEDS family
GII86_RS20315	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GII86_RS20320	COG1845	cytochrome c oxidase, subunit III
GII86_RS20325	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GII86_RS20330	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GII86_RS20335	COG2261	transglycosylase associated protein
GII86_RS20340	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GII86_RS20345	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GII86_RS20350	COG2246	polysaccharide biosynthetic process
GII86_RS20355	COG1309	transcriptional regulator
GII86_RS20365	COG3162	membrane
GII86_RS20370	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GII86_RS20375	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GII86_RS20380	COG2837	iron assimilation
GII86_RS20385	COG2822	iron ion transport
GII86_RS20390	COG0672	)-iron permease
GII86_RS20395	COG0352	thiamine-phosphate diphosphorylase activity
GII86_RS20400	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GII86_RS20405	COG0583	DNA-binding transcription factor activity
GII86_RS20410	COG1380	Effector of murein hydrolase LrgA
GII86_RS20415	COG1346	cytolysis
GII86_RS20420	COG2814	Major facilitator Superfamily
GII86_RS20425	COG4895	conserved protein (DUF2196)
GII86_RS20430	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GII86_RS20435	COG0346	lactoylglutathione lyase activity
GII86_RS20445	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII86_RS20450	COG1404	Belongs to the peptidase S8 family
GII86_RS20455	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII86_RS20455	COG1263	PTS System
GII86_RS20460	COG3711	transcriptional antiterminator
GII86_RS20465	COG1442	glycosyl transferase family 8
GII86_RS20470	COG5522	Integral membrane protein (intg_mem_TP0381)
GII86_RS20475	COG1846	Transcriptional regulator
GII86_RS20480	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GII86_RS20485	COG2234	aminopeptidase activity
GII86_RS20490	COG2357	RelA SpoT domain protein
GII86_RS20495	COG1575	Belongs to the MenA family. Type 1 subfamily
GII86_RS20510	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GII86_RS20515	COG1696	Membrane protein involved in D-alanine export
GII86_RS20520	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GII86_RS20525	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GII86_RS20530	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
GII86_RS20535	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GII86_RS20540	COG1486	melibiose metabolic process
GII86_RS20545	COG1447	Phosphotransferase system cellobiose-specific component IIA
GII86_RS20550	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII86_RS20555	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GII86_RS20570	COG2094	Belongs to the DNA glycosylase MPG family
GII86_RS20575	COG0753	catalase activity
GII86_RS20580	COG2814	Major facilitator Superfamily
GII86_RS20585	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GII86_RS20590	COG1131	(ABC) transporter
GII86_RS20610	COG1595	DNA-templated transcription, initiation
GII86_RS20615	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GII86_RS20620	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GII86_RS20625	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GII86_RS20630	COG4988	ABC transporter
GII86_RS20635	COG1294	oxidase, subunit
GII86_RS20640	COG1271	oxidase subunit
GII86_RS20645	COG3493	citrate carrier protein
GII86_RS20650	COG0501	Belongs to the peptidase M48B family
GII86_RS20660	COG0726	polysaccharide deacetylase
GII86_RS20665	COG3842	ATPase activity
GII86_RS20670	COG2508	Transcriptional regulator
GII86_RS20675	COG1012	belongs to the aldehyde dehydrogenase family
GII86_RS20680	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GII86_RS20685	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GII86_RS20695	COG4585	Histidine kinase
GII86_RS20700	COG2197	response regulator
GII86_RS20705	COG2195	Cleaves the N-terminal amino acid of tripeptides
GII86_RS20715	COG4894	glucomannan catabolic process
GII86_RS20720	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GII86_RS20725	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GII86_RS20730	COG1028	Short-chain dehydrogenase reductase Sdr
GII86_RS20735	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GII86_RS20740	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GII86_RS20745	COG2610	gluconate transmembrane transporter activity
GII86_RS20750	COG0500	methyltransferase
GII86_RS20755	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GII86_RS20770	COG0753	catalase activity
GII86_RS20770	COG0693	protein deglycase activity
GII86_RS20775	COG2851	Citrate transporter
GII86_RS20780	COG2273	Hydrolase Family 16
GII86_RS20785	COG3711	transcriptional antiterminator
GII86_RS20795	COG2270	Major facilitator Superfamily
GII86_RS20800	COG0513	Belongs to the DEAD box helicase family
GII86_RS20805	COG2755	lipolytic protein G-D-S-L family
GII86_RS20805	COG3401	FG-GAP repeat protein
GII86_RS20940	COG0697	spore germination
GII86_RS20945	COG0589	response to stress
GII86_RS20950	COG2723	6-phospho-beta-galactosidase activity
GII86_RS20955	COG2190	(PTS) system
GII86_RS20955	COG1263	PTS System
GII86_RS20955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GII86_RS20965	COG5444	nuclease activity
GII86_RS20975	COG5444	nuclease activity
GII86_RS20990	COG3507	Belongs to the glycosyl hydrolase 43 family
GII86_RS21005	COG2986	histidine ammonia-lyase
GII86_RS21010	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GII86_RS21015	COG1228	amidohydrolase
GII86_RS21020	COG0010	Belongs to the arginase family
GII86_RS21025	COG0833	amino acid
GII86_RS21030	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GII86_RS21035	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GII86_RS21040	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GII86_RS21045	COG2390	Transcriptional regulator
GII86_RS21055	COG3192	ethanolamine utilization protein
GII86_RS21060	COG2079	MmgE PrpD family protein
GII86_RS21065	COG1473	amidohydrolase
GII86_RS21070	COG1126	abc transporter atp-binding protein
GII86_RS21075	COG0765	amino acid transport
GII86_RS21080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GII86_RS21085	COG0456	acetyltransferase
GII86_RS21090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GII86_RS21095	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
GII86_RS21100	COG0561	phosphatase activity
GII86_RS21130	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GII86_RS21135	COG5294	Protein conserved in bacteria
GII86_RS21140	COG0577	efflux transmembrane transporter activity
GII86_RS21145	COG1136	(ABC) transporter
GII86_RS21150	COG2205	protein histidine kinase activity
GII86_RS21155	COG0745	RESPONSE REGULATOR receiver
GII86_RS21160	COG0191	fructose-bisphosphate aldolase activity
GII86_RS21165	COG1082	Xylose isomerase domain protein TIM barrel
GII86_RS21170	COG1082	Xylose isomerase domain protein TIM barrel
GII86_RS21175	COG0673	inositol 2-dehydrogenase activity
GII86_RS21180	COG2814	Major facilitator Superfamily
GII86_RS21185	COG1082	Xylose isomerase domain protein TIM barrel
GII86_RS21190	COG3962	Belongs to the TPP enzyme family
GII86_RS21195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GII86_RS21205	COG1012	belongs to the aldehyde dehydrogenase family
GII86_RS21210	COG1349	DNA-binding transcription factor activity
GII86_RS21215	COG0667	Aldo Keto reductase
GII86_RS21230	COG2814	Major facilitator Superfamily
GII86_RS21235	COG0326	Molecular chaperone. Has ATPase activity
GII86_RS21245	COG1028	Short-chain dehydrogenase reductase Sdr
GII86_RS21250	COG1309	transcriptional regulator
GII86_RS21255	COG1012	belongs to the aldehyde dehydrogenase family
GII86_RS21260	COG1714	RDD family
GII86_RS21270	COG1714	RDD family
GII86_RS21275	COG2311	Membrane
GII86_RS21280	COG1917	Cupin 2, conserved barrel domain protein
GII86_RS21285	COG1309	transcriptional regulator
GII86_RS21290	COG1028	Short-chain dehydrogenase reductase Sdr
GII86_RS21295	COG1846	Transcriptional regulator
GII86_RS21300	COG1380	Effector of murein hydrolase LrgA
GII86_RS21305	COG1346	cytolysis
GII86_RS21310	COG5039	Polysaccharide pyruvyl transferase
GII86_RS21315	COG1929	Belongs to the glycerate kinase type-1 family
GII86_RS21320	COG1802	Transcriptional regulator
GII86_RS21325	COG1070	Carbohydrate kinase
GII86_RS21330	COG2610	gluconate transmembrane transporter activity
GII86_RS21335	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GII86_RS21340	COG0450	alkyl hydroperoxide reductase
GII86_RS21345	COG3634	alkyl hydroperoxide reductase activity
GII86_RS21350	COG2723	6-phospho-beta-galactosidase activity
GII86_RS21365	COG2188	Transcriptional regulator
GII86_RS21375	COG1131	(ABC) transporter
GII86_RS21380	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
GII86_RS21410	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GII86_RS21425	COG1063	alcohol dehydrogenase
GII86_RS21445	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GII86_RS21450	COG0456	acetyltransferase
GII86_RS21455	COG0457	Tetratricopeptide repeat
GII86_RS21465	COG0010	Belongs to the arginase family
GII86_RS21470	COG0833	amino acid
GII86_RS21475	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GII86_RS21495	COG5658	integral membrane protein
GII86_RS21500	COG0640	Transcriptional regulator
GII86_RS21505	COG3829	transcription factor binding
GII86_RS21520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GII86_RS21525	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GII86_RS21530	COG4853	Protein conserved in bacteria
GII86_RS21535	COG4863	YycH protein
GII86_RS21540	COG5002	protein histidine kinase activity
GII86_RS21545	COG0745	RESPONSE REGULATOR receiver
GII86_RS21575	COG0346	lactoylglutathione lyase activity
GII86_RS21580	COG0305	Participates in initiation and elongation during chromosome replication
GII86_RS21595	COG3093	addiction module antidote protein HigA
GII86_RS21600	COG2807	transmembrane transport
GII86_RS21605	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GII86_RS21610	COG0359	binds to the 23S rRNA
GII86_RS21615	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
GII86_RS21620	COG4241	membrane
GII86_RS21630	COG5577	PFAM Coat F domain
GII86_RS21635	COG1733	regulation of RNA biosynthetic process
GII86_RS21640	COG1227	inorganic diphosphatase activity
GII86_RS21650	COG2271	Major facilitator Superfamily
GII86_RS21655	COG0789	Transcriptional regulator
GII86_RS21655	COG4978	Transcriptional regulator
GII86_RS21665	COG4319	ketosteroid isomerase
GII86_RS21670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GII86_RS21675	COG1846	Transcriptional regulator
GII86_RS21680	COG2153	protein acetylation
GII86_RS21685	COG2364	Membrane
GII86_RS21690	COG0456	acetyltransferase
GII86_RS21695	COG2315	Protein conserved in bacteria
GII86_RS21700	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GII86_RS21705	COG1331	Highly conserved protein containing a thioredoxin domain
GII86_RS21710	COG1266	CAAX protease self-immunity
GII86_RS21715	COG2814	Major facilitator Superfamily
GII86_RS21715	COG0477	Major facilitator Superfamily
GII86_RS21720	COG0110	maltose O-acetyltransferase activity
GII86_RS21725	COG0346	lactoylglutathione lyase activity
GII86_RS21730	COG1609	Transcriptional regulator
GII86_RS21735	COG0708	Exodeoxyribonuclease III
GII86_RS21740	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GII86_RS21745	COG0629	single-stranded DNA binding
GII86_RS21750	COG0360	Binds together with S18 to 16S ribosomal RNA
GII86_RS21755	COG0012	GTP binding
GII86_RS21760	COG0243	molybdopterin cofactor binding
GII86_RS21765	COG4481	Protein conserved in bacteria
GII86_RS21770	COG3949	Membrane
GII86_RS21780	COG1475	DNA binding
GII86_RS21785	COG1192	Involved in chromosome partitioning
GII86_RS21795	COG1475	DNA binding
GII86_RS21800	COG0357	Ribosomal RNA small subunit methyltransferase G
GII86_RS21805	COG0445	tRNA wobble uridine modification
GII86_RS21810	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GII86_RS21815	COG1847	R3H domain protein
GII86_RS21820	COG0706	membrane insertase activity
GII86_RS21825	COG0594	ribonuclease P activity