locus-tag	class	description
FC605_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FC605_RS00010	COG0592	DNA-directed DNA polymerase activity
FC605_RS00015	COG2501	S4 domain
FC605_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FC605_RS00030	COG0187	DNA topoisomerase II activity
FC605_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FC605_RS00070	COG0517	IMP dehydrogenase activity
FC605_RS00070	COG0516	GMP reductase activity
FC605_RS00075	COG1686	Belongs to the peptidase S11 family
FC605_RS00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
FC605_RS00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FC605_RS00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FC605_RS00100	COG1428	Deoxynucleoside kinase
FC605_RS00105	COG1428	Deoxynucleoside kinase
FC605_RS00110	COG1388	LysM domain
FC605_RS00110	COG3858	chitin binding
FC605_RS00115	COG1335	isochorismatase
FC605_RS00120	COG0590	tRNA wobble adenosine to inosine editing
FC605_RS00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FC605_RS00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FC605_RS00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FC605_RS00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
FC605_RS00190	COG3853	Toxic anion resistance protein (TelA)
FC605_RS00195	COG1982	Orn Lys Arg decarboxylase major
FC605_RS00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FC605_RS00205	COG3870	Protein conserved in bacteria
FC605_RS00210	COG1728	Protein conserved in bacteria
FC605_RS00215	COG0470	DNA polymerase III
FC605_RS00220	COG1774	PSP1 C-terminal conserved region
FC605_RS00225	COG4467	Involved in initiation control of chromosome replication
FC605_RS00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FC605_RS00235	COG2827	Endonuclease containing a URI domain
FC605_RS00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FC605_RS00245	COG2002	toxin-antitoxin pair type II binding
FC605_RS00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FC605_RS00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FC605_RS00255	COG0084	hydrolase, TatD family'
FC605_RS00260	COG3584	3D domain protein
FC605_RS00260	COG3583	domain protein
FC605_RS00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FC605_RS00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FC605_RS00280	COG4466	Protein conserved in bacteria
FC605_RS00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FC605_RS00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FC605_RS00300	COG0251	oxidation-reduction process
FC605_RS00305	COG2088	sporulation resulting in formation of a cellular spore
FC605_RS00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FC605_RS00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FC605_RS00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FC605_RS00325	COG0193	aminoacyl-tRNA hydrolase activity
FC605_RS00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FC605_RS00340	COG2002	toxin-antitoxin pair type II binding
FC605_RS00345	COG2244	polysaccharide biosynthetic process
FC605_RS00350	COG3956	TIGRFAM MazG family protein
FC605_RS00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FC605_RS00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FC605_RS00375	COG1098	S1 RNA binding domain
FC605_RS00390	COG2208	phosphoserine phosphatase activity
FC605_RS00395	COG2304	oxidoreductase activity
FC605_RS00400	COG0515	serine threonine protein kinase
FC605_RS00405	COG0037	tRNA processing
FC605_RS00410	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FC605_RS00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FC605_RS00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FC605_RS00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FC605_RS00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FC605_RS00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FC605_RS00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FC605_RS00445	COG0512	Glutamine amidotransferase of anthranilate synthase
FC605_RS00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FC605_RS00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FC605_RS00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FC605_RS00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FC605_RS00470	COG1396	sequence-specific DNA binding
FC605_RS00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FC605_RS00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FC605_RS00560	COG4463	regulation of RNA biosynthetic process
FC605_RS00565	COG3880	PFAM UvrB UvrC protein
FC605_RS00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
FC605_RS00575	COG0542	response to heat
FC605_RS00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FC605_RS00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
FC605_RS00590	COG4956	integral membrane protein (PIN domain superfamily)
FC605_RS00595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FC605_RS00600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FC605_RS00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FC605_RS00615	COG1045	serine acetyltransferase
FC605_RS00620	COG0215	cysteine-tRNA ligase activity
FC605_RS00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FC605_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FC605_RS00635	COG3688	RNA-binding protein containing a PIN domain
FC605_RS00640	COG1595	DNA-templated transcription, initiation
FC605_RS00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FC605_RS00655	COG0250	Participates in transcription elongation, termination and antitermination
FC605_RS00665	COG0081	regulation of translation
FC605_RS00670	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FC605_RS00680	COG2813	Specifically methylates the guanine in position
FC605_RS00685	COG0085	RNA polymerase activity
FC605_RS00690	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FC605_RS00695	COG1358	cellular component organization or biogenesis
FC605_RS00700	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FC605_RS00705	COG0049	tRNA binding
FC605_RS00710	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FC605_RS00715	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FC605_RS00720	COG0596	Alpha beta hydrolase
FC605_RS00730	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FC605_RS00735	COG0088	Forms part of the polypeptide exit tunnel
FC605_RS00745	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FC605_RS00765	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FC605_RS00775	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FC605_RS00780	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FC605_RS00790	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FC605_RS00800	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FC605_RS00805	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FC605_RS00810	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FC605_RS00815	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FC605_RS00825	COG0200	Binds to the 23S rRNA
FC605_RS00830	COG0201	protein transport
FC605_RS00835	COG0563	adenylate kinase activity
FC605_RS00840	COG0024	Methionine aminopeptidase
FC605_RS00845	COG2163	COG2163 Ribosomal protein L14E L6E L27E
FC605_RS00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FC605_RS00860	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FC605_RS00865	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FC605_RS00870	COG0202	RNA polymerase activity
FC605_RS00875	COG0203	ribosomal protein L17
FC605_RS00880	COG1122	ATPase activity
FC605_RS00885	COG1122	ATPase activity
FC605_RS00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FC605_RS00895	COG0101	tRNA pseudouridine synthase activity
FC605_RS00900	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FC605_RS00905	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FC605_RS00920	COG0860	N-Acetylmuramoyl-L-alanine amidase
FC605_RS00925	COG0489	protein tyrosine kinase activity
FC605_RS00935	COG2194	sulfuric ester hydrolase activity
FC605_RS00940	COG0726	polysaccharide deacetylase
FC605_RS01025	COG0659	secondary active sulfate transmembrane transporter activity
FC605_RS01030	COG0385	Bile acid
FC605_RS01035	COG2819	hydrolase of the alpha beta superfamily
FC605_RS01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FC605_RS01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FC605_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FC605_RS01055	COG2207	Transcriptional regulator
FC605_RS01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FC605_RS01060	COG3876	Protein conserved in bacteria
FC605_RS01065	COG1472	Belongs to the glycosyl hydrolase 3 family
FC605_RS01070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FC605_RS01075	COG1263	PTS System
FC605_RS01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FC605_RS01080	COG1737	Transcriptional regulator
FC605_RS01085	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FC605_RS01090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FC605_RS01095	COG1683	Conserved Protein
FC605_RS01125	COG1595	DNA-templated transcription, initiation
FC605_RS01130	COG5662	AntiSigma factor
FC605_RS01135	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FC605_RS01140	COG4856	YbbR-like protein
FC605_RS01145	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FC605_RS01150	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FC605_RS01160	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FC605_RS01165	COG2169	Transcriptional regulator
FC605_RS01170	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FC605_RS01175	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FC605_RS01180	COG3002	Belongs to the UPF0753 family
FC605_RS01185	COG0288	reversible hydration of carbon dioxide
FC605_RS01195	COG5609	conserved protein (DUF2294)
FC605_RS01205	COG0640	Transcriptional regulator
FC605_RS01210	COG2814	Major facilitator Superfamily
FC605_RS01230	COG1136	(ABC) transporter
FC605_RS01255	COG1113	amino acid transport
FC605_RS01270	COG2602	Beta-lactamase
FC605_RS01275	COG2124	cytochrome p450
FC605_RS01290	COG0584	glycerophosphoryl diester phosphodiesterase
FC605_RS01295	COG2271	Major facilitator Superfamily
FC605_RS01310	COG1846	Transcriptional regulator
FC605_RS01310	COG0456	acetyltransferase
FC605_RS01315	COG2271	Major facilitator Superfamily
FC605_RS01320	COG0697	spore germination
FC605_RS01325	COG1917	Cupin 2, conserved barrel domain protein
FC605_RS01325	COG2207	Transcriptional regulator
FC605_RS01330	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FC605_RS01345	COG0596	Alpha beta hydrolase
FC605_RS01350	COG1183	phosphatidylcholine synthase activity
FC605_RS01355	COG0586	Pfam SNARE associated Golgi protein
FC605_RS01360	COG0688	phosphatidylethanolamine metabolic process
FC605_RS01370	COG2312	Erythromycin esterase
FC605_RS01375	COG2207	Transcriptional regulator
FC605_RS01380	COG1054	Belongs to the UPF0176 family
FC605_RS01385	COG1301	dicarboxylic acid transport
FC605_RS01390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FC605_RS01390	COG1263	PTS System
FC605_RS01390	COG2190	(PTS) system
FC605_RS01395	COG0363	glucosamine-6-phosphate deaminase activity
FC605_RS01400	COG2188	Transcriptional regulator
FC605_RS01410	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FC605_RS01415	COG0833	amino acid
FC605_RS01420	COG2040	homocysteine
FC605_RS01430	COG1115	amino acid carrier protein
FC605_RS01435	COG2066	Belongs to the glutaminase family
FC605_RS01440	COG4191	Histidine kinase
FC605_RS01445	COG0784	Response regulator, receiver
FC605_RS01455	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FC605_RS01460	COG1012	belongs to the aldehyde dehydrogenase family
FC605_RS01465	COG2271	Major facilitator Superfamily
FC605_RS01470	COG4948	Mandelate Racemase Muconate Lactonizing
FC605_RS01475	COG2186	Transcriptional regulator
FC605_RS01480	COG2721	sulfolactate sulfo-lyase activity
FC605_RS01485	COG3173	Aminoglycoside phosphotransferase
FC605_RS01495	COG0697	spore germination
FC605_RS01500	COG0745	RESPONSE REGULATOR receiver
FC605_RS01505	COG2205	protein histidine kinase activity
FC605_RS01510	COG1131	(ABC) transporter
FC605_RS01530	COG3773	Cell wall hydrolase
FC605_RS01535	COG2304	oxidoreductase activity
FC605_RS01545	COG3540	Alkaline phosphatase
FC605_RS01550	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FC605_RS01555	COG0805	protein transport
FC605_RS01560	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FC605_RS01570	COG0477	Major facilitator Superfamily
FC605_RS01575	COG1309	transcriptional regulator
FC605_RS01580	COG0252	asparaginase activity
FC605_RS01585	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FC605_RS01590	COG1714	RDD family
FC605_RS01595	COG1405	negative regulation of cell septum assembly
FC605_RS01595	COG3012	SEC-C Motif Domain Protein
FC605_RS01600	COG3290	protein histidine kinase activity
FC605_RS01605	COG3279	Response regulator of the LytR AlgR family
FC605_RS01610	COG4555	ABC transporter
FC605_RS01615	COG1668	transmembrane transport
FC605_RS01620	COG0667	Aldo Keto reductase
FC605_RS01635	COG1595	DNA-templated transcription, initiation
FC605_RS01640	COG1595	DNA-templated transcription, initiation
FC605_RS01645	COG1876	peptidase activity
FC605_RS01650	COG0457	Tetratricopeptide repeat
FC605_RS01655	COG1028	Short-chain dehydrogenase reductase Sdr
FC605_RS01660	COG0366	Alpha amylase catalytic
FC605_RS01665	COG0803	Belongs to the bacterial solute-binding protein 9 family
FC605_RS01670	COG1121	(ABC) transporter
FC605_RS01675	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FC605_RS01680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FC605_RS01685	COG2310	stress, protein
FC605_RS01690	COG2310	stress, protein
FC605_RS01695	COG2310	stress, protein
FC605_RS01700	COG0861	Integral membrane protein TerC family
FC605_RS01710	COG3853	Toxic anion resistance protein (TelA)
FC605_RS01715	COG0477	Major facilitator Superfamily
FC605_RS01725	COG2814	Major facilitator Superfamily
FC605_RS01730	COG0640	Transcriptional regulator
FC605_RS01735	COG0517	IMP dehydrogenase activity
FC605_RS01735	COG4175	Glycine betaine
FC605_RS01740	COG4176	ABC-type proline glycine betaine transport system permease component
FC605_RS01745	COG2113	Glycine betaine
FC605_RS01750	COG1473	amidohydrolase
FC605_RS01755	COG1288	antiporter activity
FC605_RS01765	COG0366	Alpha amylase catalytic
FC605_RS01770	COG0039	L-malate dehydrogenase activity
FC605_RS01775	COG1620	l-lactate permease
FC605_RS01780	COG2814	Major facilitator Superfamily
FC605_RS01785	COG1846	Transcriptional regulator
FC605_RS01790	COG1280	lysine exporter protein (LysE YggA)
FC605_RS01795	COG3403	YqcI/YcgG family
FC605_RS01800	COG1113	amino acid transport
FC605_RS01805	COG3665	Urea carboxylase-associated protein
FC605_RS01810	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FC605_RS01815	COG1660	Displays ATPase and GTPase activities
FC605_RS01820	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FC605_RS01825	COG2226	methyltransferase
FC605_RS01830	COG0583	DNA-binding transcription factor activity
FC605_RS01835	COG3458	cephalosporin-C deacetylase activity
FC605_RS01840	COG3541	Predicted nucleotidyltransferase
FC605_RS01845	COG0506	proline dehydrogenase activity
FC605_RS01850	COG1012	belongs to the aldehyde dehydrogenase family
FC605_RS01855	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FC605_RS01860	COG2508	Transcriptional regulator
FC605_RS01865	COG3689	TIGRFAM TIGR03943 family protein
FC605_RS01870	COG0701	Predicted permease
FC605_RS01875	COG2267	carboxylic ester hydrolase activity
FC605_RS01880	COG0492	ferredoxin-NADP+ reductase activity
FC605_RS01885	COG1587	Uroporphyrinogen-III synthase
FC605_RS01885	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FC605_RS01890	COG2146	nitrite reductase [NAD(P)H] activity
FC605_RS01895	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FC605_RS01900	COG0243	molybdopterin cofactor binding
FC605_RS01905	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FC605_RS01910	COG2223	nitrite transmembrane transporter activity
FC605_RS01915	COG1469	GTP cyclohydrolase I activity
FC605_RS01920	COG1376	ErfK ybiS ycfS ynhG family protein
FC605_RS01925	COG0523	cobalamin synthesis protein
FC605_RS01930	COG0765	amino acid transport
FC605_RS01935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FC605_RS01945	COG1714	RDD family
FC605_RS01955	COG1846	Transcriptional regulator
FC605_RS01965	COG3842	ATPase activity
FC605_RS01970	COG2723	6-phospho-beta-galactosidase activity
FC605_RS01980	COG3209	COG3209 Rhs family protein
FC605_RS01985	COG0840	transmembrane signaling receptor activity
FC605_RS01985	COG3290	protein histidine kinase activity
FC605_RS01990	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FC605_RS01995	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
FC605_RS02000	COG1733	regulation of RNA biosynthetic process
FC605_RS02005	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FC605_RS02010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FC605_RS02015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FC605_RS02020	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
FC605_RS02025	COG2814	Major facilitator Superfamily
FC605_RS02035	COG0697	spore germination
FC605_RS02040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FC605_RS02050	COG2364	Membrane
FC605_RS02055	COG1126	abc transporter atp-binding protein
FC605_RS02060	COG0765	amino acid transport
FC605_RS02065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FC605_RS02070	COG0583	DNA-binding transcription factor activity
FC605_RS02075	COG0163	prenyltransferase activity
FC605_RS02080	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FC605_RS02095	COG0596	Alpha beta hydrolase
FC605_RS02100	COG3104	oligopeptide transport
FC605_RS02105	COG5434	Belongs to the glycosyl hydrolase 28 family
FC605_RS02115	COG0697	spore germination
FC605_RS02125	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FC605_RS02130	COG1136	(ABC) transporter
FC605_RS02135	COG0577	efflux transmembrane transporter activity
FC605_RS02140	COG0745	RESPONSE REGULATOR receiver
FC605_RS02145	COG3850	Histidine kinase
FC605_RS02145	COG5002	protein histidine kinase activity
FC605_RS02150	COG0457	Tetratricopeptide repeat
FC605_RS02170	COG0527	aspartate kinase activity
FC605_RS02175	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FC605_RS02180	COG4605	iron ion homeostasis
FC605_RS02185	COG4604	ABC transporter, ATP-binding protein
FC605_RS02190	COG4607	ABC-type enterochelin transport system periplasmic component
FC605_RS02195	COG2814	Major facilitator Superfamily
FC605_RS02200	COG1309	transcriptional regulator
FC605_RS02205	COG0778	Nitroreductase
FC605_RS02210	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FC605_RS02215	COG0640	Transcriptional regulator
FC605_RS02220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FC605_RS02225	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FC605_RS02230	COG1012	belongs to the aldehyde dehydrogenase family
FC605_RS02235	COG4975	Glucose uptake
FC605_RS02240	COG1028	Short-chain dehydrogenase reductase Sdr
FC605_RS02245	COG4549	nuclear export factor GLE1
FC605_RS02250	COG2372	response to copper ion
FC605_RS02250	COG1276	copper resistance
FC605_RS02255	COG1349	DNA-binding transcription factor activity
FC605_RS02265	COG2213	PTS system mannitol-specific
FC605_RS02270	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FC605_RS02275	COG0246	Mannitol dehydrogenase
FC605_RS02280	COG0473	3-isopropylmalate dehydrogenase activity
FC605_RS02290	COG0412	Dienelactone hydrolase
FC605_RS02295	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FC605_RS02305	COG0561	phosphatase activity
FC605_RS02310	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FC605_RS02315	COG1914	H( )-stimulated, divalent metal cation uptake system
FC605_RS02320	COG4336	lyase activity
FC605_RS02325	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FC605_RS02330	COG1984	allophanate hydrolase subunit 2
FC605_RS02335	COG1414	Transcriptional regulator
FC605_RS02340	COG2755	lipolytic protein G-D-S-L family
FC605_RS02350	COG2329	Antibiotic biosynthesis monooxygenase
FC605_RS02355	COG0768	penicillin binding
FC605_RS02360	COG4989	oxidoreductase activity
FC605_RS02365	COG3711	transcriptional antiterminator
FC605_RS02370	COG0318	PFAM AMP-dependent synthetase and ligase
FC605_RS02375	COG2226	methyltransferase
FC605_RS02380	COG1028	Short-chain dehydrogenase reductase Sdr
FC605_RS02385	COG1917	Cupin 2, conserved barrel domain protein
FC605_RS02390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FC605_RS02395	COG3871	stress protein (general stress protein 26)
FC605_RS02405	COG2814	Major facilitator Superfamily
FC605_RS02410	COG1522	sequence-specific DNA binding
FC605_RS02415	COG0551	DNA topoisomerase type I activity
FC605_RS02415	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FC605_RS02420	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FC605_RS02425	COG3706	GGDEF domain
FC605_RS02430	COG5298	Protein conserved in bacteria
FC605_RS02435	COG1215	transferase activity, transferring glycosyl groups
FC605_RS02445	COG0531	amino acid
FC605_RS02455	COG0028	Belongs to the TPP enzyme family
FC605_RS02470	COG1914	H( )-stimulated, divalent metal cation uptake system
FC605_RS02475	COG2261	transglycosylase associated protein
FC605_RS02480	COG4876	unkown
FC605_RS02485	COG2217	Heavy metal translocating P-type atpase
FC605_RS02490	COG3729	General stress protein
FC605_RS02495	COG0662	Cupin 2, conserved barrel domain protein
FC605_RS02500	COG2329	Antibiotic biosynthesis monooxygenase
FC605_RS02505	COG3546	catalase activity
FC605_RS02510	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FC605_RS02515	COG3290	protein histidine kinase activity
FC605_RS02520	COG4565	transcriptional regulatory protein
FC605_RS02525	COG1301	dicarboxylic acid transport
FC605_RS02530	COG0628	permease
FC605_RS02535	COG1131	(ABC) transporter
FC605_RS02540	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FC605_RS02550	COG1960	acyl-CoA dehydrogenase activity
FC605_RS02565	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FC605_RS02570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FC605_RS02575	COG1181	Belongs to the D-alanine--D-alanine ligase family
FC605_RS02580	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FC605_RS02590	COG0513	Belongs to the DEAD box helicase family
FC605_RS02595	COG3402	PFAM membrane-flanked domain
FC605_RS02600	COG3428	Bacterial PH domain
FC605_RS02605	COG0705	Rhomboid family
FC605_RS02610	COG0736	holo-[acyl-carrier-protein] synthase activity
FC605_RS02615	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FC605_RS02620	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FC605_RS02625	COG0864	Transcriptional regulator
FC605_RS02630	COG2337	Toxic component of a toxin-antitoxin (TA) module
FC605_RS02635	COG1366	Belongs to the anti-sigma-factor antagonist family
FC605_RS02640	COG1366	Belongs to the anti-sigma-factor antagonist family
FC605_RS02645	COG2172	sigma factor antagonist activity
FC605_RS02650	COG2208	phosphoserine phosphatase activity
FC605_RS02655	COG1366	Belongs to the anti-sigma-factor antagonist family
FC605_RS02660	COG2172	sigma factor antagonist activity
FC605_RS02665	COG1191	sigma factor activity
FC605_RS02670	COG2208	phosphoserine phosphatase activity
FC605_RS02675	COG2183	response to ionizing radiation
FC605_RS02685	COG3091	SprT-like family
FC605_RS02745	COG1764	response to oxidative stress
FC605_RS02750	COG1846	Transcriptional regulator
FC605_RS02760	COG3764	Sortase (surface protein transpeptidase)
FC605_RS02770	COG0604	alcohol dehydrogenase
FC605_RS02780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FC605_RS02790	COG5444	nuclease activity
FC605_RS02800	COG1476	TRANSCRIPTIONal
FC605_RS02825	COG0693	protein deglycase activity
FC605_RS02830	COG1278	Cold shock
FC605_RS02835	COG1329	Transcriptional regulator
FC605_RS02845	COG0697	spore germination
FC605_RS02850	COG1917	Cupin 2, conserved barrel domain protein
FC605_RS02850	COG2207	Transcriptional regulator
FC605_RS02855	COG0697	spore germination
FC605_RS02860	COG2207	Transcriptional regulator
FC605_RS02860	COG3708	Transcriptional regulator
FC605_RS02865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FC605_RS02870	COG0477	Major facilitator Superfamily
FC605_RS02880	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
FC605_RS02900	COG1309	transcriptional regulator
FC605_RS02905	COG0697	spore germination
FC605_RS02910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FC605_RS02915	COG2030	dehydratase
FC605_RS02920	COG3545	Serine hydrolase
FC605_RS02925	COG1733	regulation of RNA biosynthetic process
FC605_RS02930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FC605_RS02935	COG1733	regulation of RNA biosynthetic process
FC605_RS02940	COG2249	NAD(P)H dehydrogenase (quinone) activity
FC605_RS02945	COG2814	Major facilitator Superfamily
FC605_RS02950	COG1309	transcriptional regulator
FC605_RS02955	COG0640	Transcriptional regulator
FC605_RS02960	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FC605_RS02970	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FC605_RS02975	COG0697	spore germination
FC605_RS02980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FC605_RS02985	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FC605_RS02990	COG0640	Transcriptional regulator
FC605_RS02995	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FC605_RS03010	COG4585	Histidine kinase
FC605_RS03015	COG2197	response regulator
FC605_RS03020	COG2409	Drug exporters of the RND superfamily
FC605_RS03025	COG0596	Alpha beta hydrolase
FC605_RS03030	COG1811	Na channel or pump
FC605_RS03035	COG4978	Transcriptional regulator
FC605_RS03035	COG0789	Transcriptional regulator
FC605_RS03040	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FC605_RS03045	COG0778	Nitroreductase
FC605_RS03050	COG0346	lactoylglutathione lyase activity
FC605_RS03055	COG2259	Doxx family
FC605_RS03060	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FC605_RS03075	COG2323	membrane
FC605_RS03080	COG2323	membrane
FC605_RS03085	COG0071	Belongs to the small heat shock protein (HSP20) family
FC605_RS03100	COG1309	transcriptional regulator
FC605_RS03110	COG0456	acetyltransferase
FC605_RS03120	COG1113	amino acid transport
FC605_RS03125	COG2318	DinB family
FC605_RS03130	COG1846	Transcriptional regulator
FC605_RS03135	COG1033	growth of symbiont in host cell
FC605_RS03135	COG2409	Drug exporters of the RND superfamily
FC605_RS03140	COG0778	Nitroreductase
FC605_RS03145	COG1846	Transcriptional regulator
FC605_RS03150	COG2814	Major facilitator Superfamily
FC605_RS03155	COG0730	response to heat
FC605_RS03160	COG1802	Transcriptional regulator
FC605_RS03165	COG3858	chitin binding
FC605_RS03165	COG1388	LysM domain
FC605_RS03170	COG1819	glycosyl
FC605_RS03180	COG1785	Belongs to the alkaline phosphatase family
FC605_RS03185	COG5646	InterPro IPR014922
FC605_RS03195	COG0454	-acetyltransferase
FC605_RS03200	COG1078	dGTPase activity
FC605_RS03205	COG1388	LysM domain
FC605_RS03210	COG2814	Major facilitator Superfamily
FC605_RS03215	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FC605_RS03220	COG1447	Phosphotransferase system cellobiose-specific component IIA
FC605_RS03225	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FC605_RS03230	COG2723	6-phospho-beta-galactosidase activity
FC605_RS03235	COG2188	Transcriptional regulator
FC605_RS03240	COG1940	carbohydrate kinase activity
FC605_RS03245	COG1482	cell wall glycoprotein biosynthetic process
FC605_RS03250	COG4124	Belongs to the glycosyl hydrolase 26 family
FC605_RS03295	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FC605_RS03300	COG0802	atpase or kinase
FC605_RS03305	COG1214	PFAM Peptidase M22, glycoprotease
FC605_RS03310	COG0456	acetyltransferase
FC605_RS03315	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FC605_RS03320	COG0488	(ABC) transporter
FC605_RS03325	COG0315	cyclic pyranopterin monophosphate synthase activity
FC605_RS03330	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FC605_RS03335	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FC605_RS03340	COG0805	protein transport
FC605_RS03350	COG1266	CAAX protease self-immunity
FC605_RS03360	COG0459	protein refolding
FC605_RS03370	COG1073	alpha beta
FC605_RS03375	COG0457	Tetratricopeptide repeat
FC605_RS03380	COG1063	alcohol dehydrogenase
FC605_RS03385	COG2211	Major facilitator Superfamily
FC605_RS03390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FC605_RS03395	COG1842	Phage shock protein A
FC605_RS03400	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FC605_RS03405	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FC605_RS03410	COG4260	virion core protein, lumpy skin disease virus
FC605_RS03420	COG2814	Major facilitator Superfamily
FC605_RS03425	COG1063	alcohol dehydrogenase
FC605_RS03430	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FC605_RS03435	COG0823	Involved in the tonB-independent uptake of proteins
FC605_RS03450	COG2267	carboxylic ester hydrolase activity
FC605_RS03460	COG2132	Multicopper oxidase
FC605_RS03465	COG1113	amino acid transport
FC605_RS03475	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FC605_RS03480	COG0714	Associated with various cellular activities
FC605_RS03485	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
FC605_RS03490	COG1305	Transglutaminase-like
FC605_RS03495	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FC605_RS03495	COG0519	Catalyzes the synthesis of GMP from XMP
FC605_RS03510	COG2252	PERMEase
FC605_RS03515	COG3064	Membrane
FC605_RS03525	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
FC605_RS03535	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FC605_RS03540	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FC605_RS03545	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FC605_RS03550	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FC605_RS03555	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FC605_RS03560	COG0047	phosphoribosylformylglycinamidine synthase activity
FC605_RS03565	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FC605_RS03570	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FC605_RS03575	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FC605_RS03580	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FC605_RS03585	COG0138	bifunctional purine biosynthesis protein purh
FC605_RS03590	COG0151	Belongs to the GarS family
FC605_RS03595	COG1522	sequence-specific DNA binding
FC605_RS03610	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FC605_RS03615	COG1470	cell adhesion involved in biofilm formation
FC605_RS03620	COG4496	protein, YerC YecD
FC605_RS03625	COG0069	glutamate synthase activity
FC605_RS03630	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
FC605_RS03635	COG0210	DNA helicase
FC605_RS03640	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FC605_RS03645	COG4851	CamS sex pheromone cAM373 precursor
FC605_RS03650	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FC605_RS03655	COG1285	pathogenesis
FC605_RS03660	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FC605_RS03665	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FC605_RS03670	COG0154	amidase activity
FC605_RS03675	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FC605_RS03680	COG1309	transcriptional regulator
FC605_RS03685	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FC605_RS03690	COG1597	lipid kinase activity
FC605_RS03695	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FC605_RS03740	COG1201	RNA secondary structure unwinding
FC605_RS03760	COG5444	nuclease activity
FC605_RS03770	COG3586	endonuclease activity
FC605_RS03780	COG0457	Tetratricopeptide repeat
FC605_RS03790	COG0217	transcriptional regulatory protein
FC605_RS03800	COG1309	transcriptional regulator
FC605_RS03805	COG3631	Ketosteroid isomerase-related protein
FC605_RS03810	COG0702	epimerase
FC605_RS03825	COG3546	catalase activity
FC605_RS03830	COG0454	-acetyltransferase
FC605_RS03840	COG5578	integral membrane protein
FC605_RS03845	COG2972	Histidine kinase
FC605_RS03850	COG4753	response regulator
FC605_RS03850	COG2207	Transcriptional regulator
FC605_RS03855	COG1653	transport
FC605_RS03860	COG1175	transmembrane transport
FC605_RS03865	COG0395	ABC-type sugar transport system, permease component
FC605_RS03870	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FC605_RS03880	COG2755	lipolytic protein G-D-S-L family
FC605_RS03890	COG5578	integral membrane protein
FC605_RS03895	COG3401	FG-GAP repeat protein
FC605_RS03900	COG3401	FG-GAP repeat protein
FC605_RS03905	COG2755	lipolytic protein G-D-S-L family
FC605_RS03910	COG1874	Beta-galactosidase
FC605_RS03920	COG1653	transport
FC605_RS03925	COG4209	transmembrane transport
FC605_RS03930	COG0395	ABC-type sugar transport system, permease component
FC605_RS03935	COG1486	melibiose metabolic process
FC605_RS03940	COG2323	membrane
FC605_RS03945	COG2329	Antibiotic biosynthesis monooxygenase
FC605_RS03950	COG0346	lactoylglutathione lyase activity
FC605_RS03965	COG5583	Uncharacterized small protein (DUF2292)
FC605_RS03970	COG0670	Belongs to the BI1 family
FC605_RS03975	COG0697	spore germination
FC605_RS03980	COG1846	Transcriptional regulator
FC605_RS03985	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FC605_RS03995	COG2124	cytochrome p450
FC605_RS03995	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FC605_RS04010	COG1368	sulfuric ester hydrolase activity
FC605_RS04015	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FC605_RS04020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FC605_RS04025	COG1442	glycosyl transferase family 8
FC605_RS04030	COG1216	Glycosyl transferase, family 2
FC605_RS04035	COG1442	glycosyl transferase family 8
FC605_RS04040	COG2223	nitrite transmembrane transporter activity
FC605_RS04045	COG1011	Hydrolase
FC605_RS04050	COG0531	amino acid
FC605_RS04055	COG1012	belongs to the aldehyde dehydrogenase family
FC605_RS04060	COG0840	transmembrane signaling receptor activity
FC605_RS04065	COG0488	(ABC) transporter
FC605_RS04075	COG0789	Transcriptional regulator
FC605_RS04080	COG2814	Major facilitator Superfamily
FC605_RS04095	COG0488	(ABC) transporter
FC605_RS04100	COG0513	Belongs to the DEAD box helicase family
FC605_RS04105	COG0456	acetyltransferase
FC605_RS04110	COG2130	NADP-dependent
FC605_RS04115	COG1120	ATPase activity
FC605_RS04120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FC605_RS04125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FC605_RS04130	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FC605_RS04145	COG3866	Pectate lyase
FC605_RS04150	COG0471	metal ion transport
FC605_RS04155	COG3290	protein histidine kinase activity
FC605_RS04160	COG4565	transcriptional regulatory protein
FC605_RS04165	COG3181	Tripartite tricarboxylate transporter family receptor
FC605_RS04170	COG2851	Citrate transporter
FC605_RS04175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FC605_RS04180	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
FC605_RS04185	COG1254	Belongs to the acylphosphatase family
FC605_RS04190	COG2258	MOSC domain
FC605_RS04210	COG0024	Methionine aminopeptidase
FC605_RS04215	COG1263	PTS System
FC605_RS04215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FC605_RS04220	COG1368	sulfuric ester hydrolase activity
FC605_RS04235	COG1115	amino acid carrier protein
FC605_RS04240	COG0531	amino acid
FC605_RS04255	COG0697	spore germination
FC605_RS04260	COG1263	PTS System
FC605_RS04260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FC605_RS04265	COG0366	Alpha amylase catalytic
FC605_RS04270	COG2188	Transcriptional regulator
FC605_RS04275	COG0778	Nitroreductase
FC605_RS04280	COG0737	Belongs to the 5'-nucleotidase family
FC605_RS04285	COG0693	protein deglycase activity
FC605_RS04290	COG2814	Major facilitator Superfamily
FC605_RS04295	COG4840	Belongs to the UPF0435 family
FC605_RS04300	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FC605_RS04305	COG4980	gas vesicle protein
FC605_RS04310	COG1295	ribonuclease BN
FC605_RS04315	COG0477	Major facilitator Superfamily
FC605_RS04320	COG0387	Pfam Sodium calcium exchanger
FC605_RS04330	COG0668	transmembrane transport
FC605_RS04335	COG0535	radical SAM domain protein
FC605_RS04345	COG0726	polysaccharide deacetylase
FC605_RS04350	COG2084	Dehydrogenase
FC605_RS04355	COG0598	Magnesium transport protein CorA
FC605_RS04360	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FC605_RS04365	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FC605_RS04375	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FC605_RS04380	COG4637	Psort location Cytoplasmic, score
FC605_RS04390	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FC605_RS04395	COG0022	dehydrogenase e1 component
FC605_RS04400	COG0508	dehydrogenase complex catalyzes the overall conversion of
FC605_RS04405	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FC605_RS04410	COG3284	Transcriptional regulator
FC605_RS04420	COG1742	UPF0060 membrane protein
FC605_RS04440	COG4842	Belongs to the WXG100 family
FC605_RS04445	COG1486	melibiose metabolic process
FC605_RS04450	COG1737	Transcriptional regulator
FC605_RS04455	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FC605_RS04455	COG1263	PTS System
FC605_RS04460	COG1132	(ABC) transporter
FC605_RS04465	COG1132	(ABC) transporter
FC605_RS04470	COG2259	Doxx family
FC605_RS04475	COG2514	catechol 2,3-dioxygenase activity
FC605_RS04480	COG4585	Histidine kinase
FC605_RS04485	COG2197	response regulator
FC605_RS04490	COG1131	(ABC) transporter
FC605_RS04495	COG1511	domain protein
FC605_RS04495	COG0842	Transport permease protein
FC605_RS04500	COG0842	Transport permease protein
FC605_RS04505	COG1695	Transcriptional regulator
FC605_RS04510	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FC605_RS04520	COG1309	transcriptional regulator
FC605_RS04525	COG2814	Major facilitator Superfamily
FC605_RS04530	COG2318	DinB family
FC605_RS04535	COG2814	Major facilitator Superfamily
FC605_RS04540	COG1846	Transcriptional regulator
FC605_RS04545	COG0392	lysyltransferase activity
FC605_RS04545	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FC605_RS04550	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FC605_RS04555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FC605_RS04560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FC605_RS04565	COG0384	phenazine biosynthesis protein PhzF
FC605_RS04570	COG0778	Nitroreductase
FC605_RS04585	COG1090	epimerase
FC605_RS04590	COG2137	regulation of response to DNA damage stimulus
FC605_RS04600	COG2814	Major facilitator Superfamily
FC605_RS04615	COG3103	Sh3 type 3 domain protein
FC605_RS04620	COG5658	integral membrane protein
FC605_RS04625	COG0596	Alpha beta hydrolase
FC605_RS04630	COG0463	Glycosyl transferase, family 2
FC605_RS04635	COG4485	Bacterial membrane protein, YfhO
FC605_RS04640	COG1988	membrane-bound metal-dependent
FC605_RS04645	COG1194	a g-specific adenine glycosylase
FC605_RS04655	COG1028	Short-chain dehydrogenase reductase Sdr
FC605_RS04670	COG3557	Belongs to the UPF0374 family
FC605_RS04675	COG1132	(ABC) transporter
FC605_RS04680	COG4129	membrane
FC605_RS04685	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FC605_RS04690	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FC605_RS04695	COG0735	belongs to the Fur family
FC605_RS04805	COG4326	sporulation control protein
FC605_RS04815	COG5577	PFAM Coat F domain
FC605_RS04820	COG3340	Belongs to the peptidase S51 family
FC605_RS04825	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FC605_RS04830	COG0277	FAD linked oxidase domain protein
FC605_RS04840	COG0753	catalase activity
FC605_RS04845	COG1116	anion transmembrane transporter activity
FC605_RS04850	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FC605_RS04855	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FC605_RS04860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FC605_RS04870	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FC605_RS04880	COG1476	TRANSCRIPTIONal
FC605_RS04890	COG3382	B3 4 domain protein
FC605_RS04905	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FC605_RS04910	COG0789	Transcriptional regulator
FC605_RS04915	COG1664	Polymer-forming cytoskeletal
FC605_RS04920	COG1664	Polymer-forming cytoskeletal
FC605_RS04925	COG2766	serine protein kinase
FC605_RS04930	COG2718	Belongs to the UPF0229 family
FC605_RS04935	COG1846	Transcriptional regulator
FC605_RS04940	COG1566	PFAM secretion protein HlyD family protein
FC605_RS04945	COG2814	Major facilitator Superfamily
FC605_RS04950	COG0655	NAD(P)H dehydrogenase (quinone) activity
FC605_RS04970	COG1725	Transcriptional regulator
FC605_RS04975	COG1131	(ABC) transporter
FC605_RS04980	COG1131	(ABC) transporter
FC605_RS04985	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FC605_RS04990	COG1278	Cold shock
FC605_RS05000	COG1464	Belongs to the NlpA lipoprotein family
FC605_RS05005	COG3706	GGDEF domain
FC605_RS05010	COG1823	symporter activity
FC605_RS05030	COG5577	PFAM Coat F domain
FC605_RS05035	COG4085	toxin activity
FC605_RS05035	COG0737	Belongs to the 5'-nucleotidase family
FC605_RS05035	COG1525	nuclease
FC605_RS05040	COG3764	Sortase (surface protein transpeptidase)
FC605_RS05045	COG0564	pseudouridine synthase activity
FC605_RS05055	COG0517	IMP dehydrogenase activity
FC605_RS05060	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FC605_RS05065	COG3153	acetyltransferase
FC605_RS05065	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FC605_RS05075	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FC605_RS05080	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FC605_RS05085	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FC605_RS05090	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FC605_RS05095	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FC605_RS05100	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FC605_RS05105	COG4585	Histidine kinase
FC605_RS05105	COG2203	Gaf domain
FC605_RS05110	COG2197	response regulator
FC605_RS05115	COG0431	NADPH-dependent FMN reductase
FC605_RS05130	COG1388	LysM domain
FC605_RS05130	COG0791	NLP P60 protein
FC605_RS05135	COG1959	2 iron, 2 sulfur cluster binding
FC605_RS05145	COG2719	SpoVR family
FC605_RS05150	COG1785	Belongs to the alkaline phosphatase family
FC605_RS05155	COG1388	LysM domain
FC605_RS05155	COG0791	NLP P60 protein
FC605_RS05160	COG0583	DNA-binding transcription factor activity
FC605_RS05165	COG0372	Belongs to the citrate synthase family
FC605_RS05170	COG1028	Short-chain dehydrogenase reductase Sdr
FC605_RS05175	COG0531	amino acid
FC605_RS05180	COG0733	neurotransmitter:sodium symporter activity
FC605_RS05185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FC605_RS05190	COG0456	acetyltransferase
FC605_RS05205	COG1595	DNA-templated transcription, initiation
FC605_RS05210	COG0667	Aldo Keto reductase
FC605_RS05215	COG0204	Acyl-transferase
FC605_RS05220	COG1253	flavin adenine dinucleotide binding
FC605_RS05225	COG0789	Transcriptional regulator
FC605_RS05230	COG0436	Aminotransferase
FC605_RS05235	COG1253	flavin adenine dinucleotide binding
FC605_RS05240	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FC605_RS05245	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FC605_RS05250	COG0584	glycerophosphoryl diester phosphodiesterase
FC605_RS05260	COG0668	transmembrane transport
FC605_RS05265	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FC605_RS05270	COG0726	polysaccharide deacetylase
FC605_RS05275	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FC605_RS05280	COG1757	Na H antiporter
FC605_RS05285	COG0589	response to stress
FC605_RS05295	COG1132	(ABC) transporter
FC605_RS05300	COG1132	(ABC) transporter
FC605_RS05305	COG0702	epimerase
FC605_RS05325	COG0189	ligase activity
FC605_RS05330	COG0189	ligase activity
FC605_RS05335	COG4399	Belongs to the UPF0754 family
FC605_RS05340	COG3679	Belongs to the UPF0342 family
FC605_RS05345	COG4335	DNA alkylation repair
FC605_RS05350	COG0561	phosphatase activity
FC605_RS05355	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FC605_RS05360	COG0475	glutathione-regulated potassium exporter activity
FC605_RS05365	COG0490	domain, Protein
FC605_RS05375	COG1024	Enoyl-CoA hydratase
FC605_RS05385	COG4152	abc transporter atp-binding protein
FC605_RS05390	COG1668	transmembrane transport
FC605_RS05395	COG0420	3'-5' exonuclease activity
FC605_RS05400	COG4717	serine-type aminopeptidase activity
FC605_RS05405	COG3481	metal-dependent phosphohydrolase, HD sub domain
FC605_RS05415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FC605_RS05445	COG1846	Transcriptional regulator
FC605_RS05450	COG4980	gas vesicle protein
FC605_RS05465	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FC605_RS05470	COG0537	adenosine 5'-monophosphoramidase activity
FC605_RS05475	COG1131	(ABC) transporter
FC605_RS05480	COG4473	ABC transporter
FC605_RS05490	COG1473	amidohydrolase
FC605_RS05495	COG3069	C4-dicarboxylate transmembrane transporter activity
FC605_RS05505	COG2329	Antibiotic biosynthesis monooxygenase
FC605_RS05510	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FC605_RS05515	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FC605_RS05520	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FC605_RS05525	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FC605_RS05530	COG1309	transcriptional regulator
FC605_RS05535	COG1511	domain protein
FC605_RS05540	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FC605_RS05545	COG4377	Putative membrane peptidase family (DUF2324)
FC605_RS05555	COG1363	Peptidase, m42
FC605_RS05560	COG4405	Protein conserved in bacteria
FC605_RS05565	COG1301	dicarboxylic acid transport
FC605_RS05580	COG0095	Lipoate-protein ligase
FC605_RS05585	COG0702	epimerase
FC605_RS05590	COG0318	PFAM AMP-dependent synthetase and ligase
FC605_RS05600	COG0501	Belongs to the peptidase M48B family
FC605_RS05610	COG0456	acetyltransferase
FC605_RS05615	COG0604	alcohol dehydrogenase
FC605_RS05620	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FC605_RS05625	COG0406	alpha-ribazole phosphatase activity
FC605_RS05630	COG0183	Belongs to the thiolase family
FC605_RS05635	COG0318	PFAM AMP-dependent synthetase and ligase
FC605_RS05640	COG1268	BioY protein
FC605_RS05650	COG0723	plastoquinol--plastocyanin reductase activity
FC605_RS05650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FC605_RS05655	COG1028	Short-chain dehydrogenase reductase Sdr
FC605_RS05665	COG4903	ComK protein
FC605_RS05670	COG1028	Short-chain dehydrogenase reductase Sdr
FC605_RS05680	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FC605_RS05695	COG0398	Pfam SNARE associated Golgi protein
FC605_RS05700	COG0681	Belongs to the peptidase S26 family
FC605_RS05705	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FC605_RS05710	COG1846	Transcriptional regulator
FC605_RS05715	COG0738	Major facilitator superfamily
FC605_RS05720	COG0673	inositol 2-dehydrogenase activity
FC605_RS05725	COG0561	phosphatase activity
FC605_RS05730	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FC605_RS05735	COG1609	Transcriptional regulator
FC605_RS05740	COG3180	Ammonia monooxygenase
FC605_RS05745	COG0477	Major facilitator Superfamily
FC605_RS05745	COG2814	Major facilitator Superfamily
FC605_RS05750	COG4533	DNA binding
FC605_RS05760	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
FC605_RS05765	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
FC605_RS05770	COG1074	ATP-dependent DNA helicase activity
FC605_RS05775	COG0420	3'-5' exonuclease activity
FC605_RS05780	COG0419	ATPase involved in DNA repair
FC605_RS05785	COG1403	HNH endonuclease
FC605_RS05825	COG5337	Spore coat protein CotH
FC605_RS05830	COG0179	Fumarylacetoacetate (FAA) hydrolase
FC605_RS05840	COG1404	Belongs to the peptidase S8 family
FC605_RS05855	COG2318	DinB family
FC605_RS05860	COG1562	ergosterol biosynthetic process
FC605_RS05865	COG0534	Mate efflux family protein
FC605_RS05870	COG1917	Cupin 2, conserved barrel domain protein
FC605_RS05870	COG2207	Transcriptional regulator
FC605_RS05875	COG1609	Transcriptional regulator
FC605_RS05880	COG0673	inositol 2-dehydrogenase activity
FC605_RS05885	COG2318	DinB family
FC605_RS05890	COG1279	arginine transmembrane transporter activity
FC605_RS05895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FC605_RS05900	COG1357	PFAM Pentapeptide repeats (8 copies)
FC605_RS05905	COG2267	carboxylic ester hydrolase activity
FC605_RS05910	COG0529	Catalyzes the synthesis of activated sulfate
FC605_RS05915	COG2046	Belongs to the sulfate adenylyltransferase family
FC605_RS05920	COG0175	sulfate reduction
FC605_RS05925	COG2045	Belongs to the ComB family
FC605_RS05930	COG1809	phosphosulfolactate synthase activity
FC605_RS05935	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FC605_RS05940	COG4948	Mandelate Racemase Muconate Lactonizing
FC605_RS05945	COG2814	Major facilitator Superfamily
FC605_RS05950	COG0454	-acetyltransferase
FC605_RS05955	COG2153	protein acetylation
FC605_RS05960	COG0646	methionine synthase
FC605_RS05960	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FC605_RS05965	COG1666	GTP binding
FC605_RS05970	COG2996	Protein conserved in bacteria
FC605_RS05990	COG1695	Transcriptional regulator
FC605_RS06005	COG3227	Zinc metalloprotease (Elastase)
FC605_RS06010	COG1307	EDD domain protein, DegV family
FC605_RS06015	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FC605_RS06030	COG0561	phosphatase activity
FC605_RS06035	COG1073	alpha beta
FC605_RS06040	COG2151	metal-sulfur cluster biosynthetic enzyme
FC605_RS06050	COG0277	FAD linked oxidase domain protein
FC605_RS06055	COG2271	Major facilitator Superfamily
FC605_RS06060	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FC605_RS06065	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FC605_RS06075	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FC605_RS06080	COG0505	Belongs to the CarA family
FC605_RS06085	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FC605_RS06090	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FC605_RS06105	COG2267	carboxylic ester hydrolase activity
FC605_RS06115	COG1744	ABC transporter substrate-binding protein PnrA-like
FC605_RS06130	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FC605_RS06135	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FC605_RS06140	COG5504	Zn-dependent protease
FC605_RS06145	COG0444	Belongs to the ABC transporter superfamily
FC605_RS06150	COG4608	Belongs to the ABC transporter superfamily
FC605_RS06160	COG0601	transmembrane transport
FC605_RS06165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FC605_RS06175	COG0180	Tryptophanyl-tRNA synthetase
FC605_RS06180	COG4166	transmembrane transport
FC605_RS06185	COG0601	transmembrane transport
FC605_RS06190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FC605_RS06195	COG0444	Belongs to the ABC transporter superfamily
FC605_RS06200	COG4608	Belongs to the ABC transporter superfamily
FC605_RS06205	COG2814	Major facilitator Superfamily
FC605_RS06210	COG0456	acetyltransferase
FC605_RS06215	COG1393	Belongs to the ArsC family
FC605_RS06220	COG0861	Integral membrane protein TerC family
FC605_RS06230	COG4862	establishment of competence for transformation
FC605_RS06240	COG4469	Competence protein
FC605_RS06245	COG1164	Oligoendopeptidase f
FC605_RS06260	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FC605_RS06265	COG2346	COG2346, Truncated hemoglobins
FC605_RS06270	COG0741	lytic transglycosylase activity
FC605_RS06275	COG4116	CYTH
FC605_RS06285	COG2357	RelA SpoT domain protein
FC605_RS06290	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FC605_RS06295	COG0564	pseudouridine synthase activity
FC605_RS06300	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FC605_RS06305	COG0475	glutathione-regulated potassium exporter activity
FC605_RS06305	COG0569	domain protein
FC605_RS06310	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FC605_RS06315	COG0352	thiamine-phosphate diphosphorylase activity
FC605_RS06320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FC605_RS06325	COG2104	thiamine diphosphate biosynthetic process
FC605_RS06330	COG2022	thiamine diphosphate biosynthetic process
FC605_RS06335	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FC605_RS06340	COG0351	phosphomethylpyrimidine kinase
FC605_RS06345	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FC605_RS06400	COG0210	DNA helicase
FC605_RS06410	COG2153	protein acetylation
FC605_RS06415	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FC605_RS06420	COG2382	esterase
FC605_RS06425	COG0626	cystathionine gamma-synthase activity
FC605_RS06430	COG0626	cystathionine gamma-synthase activity
FC605_RS06435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FC605_RS06440	COG5505	Protein of unknown function (DUF819)
FC605_RS06460	COG5444	nuclease activity
FC605_RS06530	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FC605_RS06535	COG1028	Short-chain dehydrogenase reductase Sdr
FC605_RS06545	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FC605_RS06545	COG3711	transcriptional antiterminator
FC605_RS06550	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FC605_RS06550	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FC605_RS06550	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FC605_RS06555	COG1482	cell wall glycoprotein biosynthetic process
FC605_RS06565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FC605_RS06575	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FC605_RS06595	COG0109	protoheme IX farnesyltransferase activity
FC605_RS06605	COG0726	polysaccharide deacetylase
FC605_RS06620	COG5504	Zn-dependent protease
FC605_RS06625	COG2205	protein histidine kinase activity
FC605_RS06635	COG3383	formate dehydrogenase (NAD+) activity
FC605_RS06640	COG2427	Protein of unknown function (DUF1641)
FC605_RS06650	COG1051	belongs to the nudix hydrolase family
FC605_RS06660	COG2124	cytochrome p450
FC605_RS06665	COG1819	glycosyl
FC605_RS06675	COG1587	Uroporphyrinogen-III synthase
FC605_RS06680	COG0390	transport system, permease component
FC605_RS06685	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FC605_RS06690	COG0697	spore germination
FC605_RS06695	COG4297	protein containing double-stranded beta helix domain
FC605_RS06705	COG1252	NADH dehydrogenase
FC605_RS06710	COG1904	glucuronate isomerase
FC605_RS06715	COG2211	Major facilitator Superfamily
FC605_RS06720	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FC605_RS06725	COG1063	alcohol dehydrogenase
FC605_RS06730	COG1312	Catalyzes the dehydration of D-mannonate
FC605_RS06735	COG1028	Short-chain dehydrogenase reductase Sdr
FC605_RS06740	COG2271	Major facilitator Superfamily
FC605_RS06745	COG1609	Transcriptional regulator
FC605_RS06750	COG0246	Mannitol dehydrogenase
FC605_RS06755	COG2721	sulfolactate sulfo-lyase activity
FC605_RS06760	COG0730	response to heat
FC605_RS06765	COG2318	DinB family
FC605_RS06770	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FC605_RS06775	COG0457	Tetratricopeptide repeat
FC605_RS06785	COG2350	Protein conserved in bacteria
FC605_RS06790	COG5632	N-Acetylmuramoyl-L-alanine amidase
FC605_RS06790	COG3409	Peptidoglycan-binding domain 1 protein
FC605_RS06790	COG1388	LysM domain
FC605_RS06800	COG4195	phage-related replication protein
FC605_RS06805	COG3546	catalase activity
FC605_RS06810	COG2856	Zn peptidase
FC605_RS06815	COG1396	sequence-specific DNA binding
FC605_RS06825	COG1522	sequence-specific DNA binding
FC605_RS06830	COG1484	DNA-dependent DNA replication
FC605_RS06850	COG1595	DNA-templated transcription, initiation
FC605_RS06855	COG5484	DNA packaging
FC605_RS06855	COG3728	DNA packaging
FC605_RS06860	COG1783	phage Terminase large subunit
FC605_RS06865	COG5518	Phage portal protein
FC605_RS06870	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FC605_RS06875	COG4653	Phage capsid family
FC605_RS06925	COG5412	phage tail tape measure protein
FC605_RS06925	COG3953	SLT domain
FC605_RS06930	COG1652	LysM domain
FC605_RS06935	COG4193	domain, Protein
FC605_RS06945	COG3628	GPW Gp25 family protein
FC605_RS06950	COG3299	homolog of phage Mu protein gp47
FC605_RS06955	COG3778	Protein conserved in bacteria
FC605_RS06995	COG5632	N-Acetylmuramoyl-L-alanine amidase
FC605_RS06995	COG3409	Peptidoglycan-binding domain 1 protein
FC605_RS07015	COG0306	phosphate transporter
FC605_RS07020	COG1392	Phosphate transport regulator
FC605_RS07025	COG0531	amino acid
FC605_RS07030	COG0346	lactoylglutathione lyase activity
FC605_RS07035	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FC605_RS07040	COG0463	Glycosyl transferase, family 2
FC605_RS07050	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FC605_RS07055	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FC605_RS07060	COG2362	D-Aminopeptidase
FC605_RS07065	COG0601	transmembrane transport
FC605_RS07070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FC605_RS07075	COG0444	Belongs to the ABC transporter superfamily
FC605_RS07080	COG4166	transmembrane transport
FC605_RS07085	COG1619	proteins homologs of microcin C7 resistance protein MccF
FC605_RS07090	COG4948	Mandelate Racemase Muconate Lactonizing
FC605_RS07095	COG0791	NLP P60 protein
FC605_RS07100	COG4608	Belongs to the ABC transporter superfamily
FC605_RS07105	COG2706	6-phosphogluconolactonase activity
FC605_RS07115	COG1607	acyl-coa hydrolase
FC605_RS07120	COG1017	nitric oxide dioxygenase activity
FC605_RS07120	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FC605_RS07130	COG2323	membrane
FC605_RS07135	COG2318	DinB family
FC605_RS07140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FC605_RS07145	COG2076	Multidrug Resistance protein
FC605_RS07150	COG2076	Multidrug Resistance protein
FC605_RS07155	COG0788	formyltetrahydrofolate deformylase activity
FC605_RS07160	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FC605_RS07165	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FC605_RS07170	COG1764	response to oxidative stress
FC605_RS07175	COG1846	Transcriptional regulator
FC605_RS07180	COG1764	response to oxidative stress
FC605_RS07190	COG0590	tRNA wobble adenosine to inosine editing
FC605_RS07200	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FC605_RS07205	COG1404	Belongs to the peptidase S8 family
FC605_RS07210	COG1366	Belongs to the anti-sigma-factor antagonist family
FC605_RS07215	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FC605_RS07220	COG1122	ATPase activity
FC605_RS07225	COG4721	ABC-type cobalt transport system, permease component
FC605_RS07235	COG0745	RESPONSE REGULATOR receiver
FC605_RS07240	COG3850	Histidine kinase
FC605_RS07240	COG5002	protein histidine kinase activity
FC605_RS07245	COG3212	peptidase
FC605_RS07250	COG3212	peptidase
FC605_RS07260	COG2239	Acts as a magnesium transporter
FC605_RS07265	COG0789	Transcriptional regulator
FC605_RS07280	COG1846	Transcriptional regulator
FC605_RS07285	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FC605_RS07290	COG0726	polysaccharide deacetylase
FC605_RS07295	COG1408	metallophosphoesterase
FC605_RS07305	COG0463	Glycosyl transferase, family 2
FC605_RS07310	COG1793	dna ligase
FC605_RS07310	COG3285	dna ligase
FC605_RS07315	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FC605_RS07320	COG5001	Diguanylate cyclase
FC605_RS07320	COG3300	MHYT domain
FC605_RS07325	COG0586	Pfam SNARE associated Golgi protein
FC605_RS07330	COG0861	Integral membrane protein TerC family
FC605_RS07335	COG1191	sigma factor activity
FC605_RS07355	COG0501	Belongs to the peptidase M48B family
FC605_RS07360	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FC605_RS07375	COG3594	Acyltransferase
FC605_RS07380	COG5002	protein histidine kinase activity
FC605_RS07385	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FC605_RS07395	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FC605_RS07400	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
FC605_RS07405	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FC605_RS07410	COG0436	Aminotransferase
FC605_RS07415	COG1850	ribulose-bisphosphate carboxylase activity
FC605_RS07420	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
FC605_RS07425	COG0235	Class ii aldolase
FC605_RS07430	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FC605_RS07435	COG3339	Conserved Protein
FC605_RS07450	COG3852	Histidine kinase
FC605_RS07455	COG1846	Transcriptional regulator
FC605_RS07460	COG1360	Flagellar Motor Protein
FC605_RS07465	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FC605_RS07470	COG0542	response to heat
FC605_RS07475	COG3949	Membrane
FC605_RS07480	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FC605_RS07485	COG0720	synthase
FC605_RS07490	COG0602	queuosine metabolic process
FC605_RS07495	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FC605_RS07500	COG1733	regulation of RNA biosynthetic process
FC605_RS07505	COG1028	Short-chain dehydrogenase reductase Sdr
FC605_RS07510	COG1388	LysM domain
FC605_RS07510	COG4641	Protein conserved in bacteria
FC605_RS07515	COG1388	LysM domain
FC605_RS07520	COG3858	chitin binding
FC605_RS07530	COG4873	Protein conserved in bacteria
FC605_RS07540	COG3773	Cell wall hydrolase
FC605_RS07545	COG2244	polysaccharide biosynthetic process
FC605_RS07555	COG2217	Heavy metal translocating P-type atpase
FC605_RS07565	COG0006	proline dipeptidase activity
FC605_RS07570	COG1609	Transcriptional regulator
FC605_RS07575	COG3711	transcriptional antiterminator
FC605_RS07580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FC605_RS07580	COG2190	(PTS) system
FC605_RS07580	COG1263	PTS System
FC605_RS07585	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FC605_RS07590	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FC605_RS07600	COG1533	DNA photolyase activity
FC605_RS07605	COG0456	acetyltransferase
FC605_RS07610	COG0840	transmembrane signaling receptor activity
FC605_RS07615	COG2084	Dehydrogenase
FC605_RS07620	COG2340	Cysteine-rich secretory protein family
FC605_RS07625	COG0768	penicillin binding
FC605_RS07630	COG4191	Histidine kinase
FC605_RS07635	COG0436	Aminotransferase
FC605_RS07645	COG0835	chemotaxis
FC605_RS07645	COG0784	Response regulator, receiver
FC605_RS07655	COG2814	Major facilitator Superfamily
FC605_RS07660	COG1376	ErfK ybiS ycfS ynhG family protein
FC605_RS07665	COG1408	metallophosphoesterase
FC605_RS07670	COG1028	Short-chain dehydrogenase reductase Sdr
FC605_RS07675	COG2200	EAL domain
FC605_RS07680	COG4703	Protein of unknown function (DUF1797)
FC605_RS07685	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
FC605_RS07695	COG0517	IMP dehydrogenase activity
FC605_RS07700	COG0583	DNA-binding transcription factor activity
FC605_RS07705	COG0716	FMN binding
FC605_RS07715	COG0716	FMN binding
FC605_RS07720	COG2171	N-acyltransferase activity
FC605_RS07725	COG1473	amidohydrolase
FC605_RS07735	COG0668	transmembrane transport
FC605_RS07740	COG0450	alkyl hydroperoxide reductase
FC605_RS07745	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FC605_RS07760	COG0746	molybdenum cofactor guanylyltransferase activity
FC605_RS07765	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FC605_RS07770	COG0303	'Molybdopterin
FC605_RS07775	COG1763	Mo-molybdopterin cofactor biosynthetic process
FC605_RS07780	COG0314	molybdopterin synthase activity
FC605_RS07785	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FC605_RS07790	COG1132	(ABC) transporter
FC605_RS07795	COG1132	(ABC) transporter
FC605_RS07805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FC605_RS07810	COG1136	(ABC) transporter
FC605_RS07815	COG0577	efflux transmembrane transporter activity
FC605_RS07820	COG1349	DNA-binding transcription factor activity
FC605_RS07825	COG1105	Belongs to the carbohydrate kinase PfkB family
FC605_RS07830	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FC605_RS07830	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FC605_RS07830	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FC605_RS07835	COG0681	Belongs to the peptidase S26 family
FC605_RS07845	COG0488	(ABC) transporter
FC605_RS07850	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FC605_RS07855	COG2309	aminopeptidase activity
FC605_RS07865	COG1077	Cell shape determining protein MreB Mrl
FC605_RS07870	COG2002	toxin-antitoxin pair type II binding
FC605_RS07875	COG3852	Histidine kinase
FC605_RS07880	COG2105	PFAM AIG2 family protein
FC605_RS07880	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FC605_RS07885	COG0569	domain protein
FC605_RS07890	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FC605_RS07895	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FC605_RS07900	COG5503	Protein of unknown function (DUF1447)
FC605_RS07905	COG0561	phosphatase activity
FC605_RS07910	COG0242	peptide deformylase activity
FC605_RS07920	COG0497	DNA recombination
FC605_RS07925	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FC605_RS07930	COG0022	dehydrogenase e1 component
FC605_RS07935	COG0508	dehydrogenase complex catalyzes the overall conversion of
FC605_RS07940	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FC605_RS07945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FC605_RS07955	COG1982	Orn Lys Arg decarboxylase major
FC605_RS07960	COG4476	Belongs to the UPF0223 family
FC605_RS07965	COG4493	Belongs to the UPF0637 family
FC605_RS07975	COG0483	inositol monophosphate 1-phosphatase activity
FC605_RS07985	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FC605_RS08005	COG1595	DNA-templated transcription, initiation
FC605_RS08025	COG1217	gtp-binding protein TYPA
FC605_RS08035	COG4896	Protein conserved in bacteria
FC605_RS08045	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FC605_RS08050	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FC605_RS08055	COG2066	Belongs to the glutaminase family
FC605_RS08060	COG4838	Belongs to the UPF0358 family
FC605_RS08065	COG0772	Belongs to the SEDS family
FC605_RS08070	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FC605_RS08075	COG1612	heme a metabolic process
FC605_RS08080	COG0109	protoheme IX farnesyltransferase activity
FC605_RS08085	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FC605_RS08085	COG2010	Cytochrome c
FC605_RS08090	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FC605_RS08095	COG1845	cytochrome c oxidase, subunit III
FC605_RS08100	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FC605_RS08105	COG3336	cytochrome c oxidase
FC605_RS08115	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FC605_RS08120	COG2340	Cysteine-rich secretory protein family
FC605_RS08135	COG3679	Belongs to the UPF0342 family
FC605_RS08140	COG4471	UPF0298 protein
FC605_RS08145	COG0742	ribosomal rna small subunit methyltransferase
FC605_RS08150	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FC605_RS08155	COG3314	Sporulation integral membrane protein YlbJ
FC605_RS08160	COG1752	Esterase of the alpha-beta hydrolase superfamily
FC605_RS08165	COG3480	Lon protease (S16) C-terminal proteolytic domain
FC605_RS08170	COG1323	Belongs to the UPF0348 family
FC605_RS08180	COG1399	metal-binding, possibly nucleic acid-binding protein
FC605_RS08195	COG0454	-acetyltransferase
FC605_RS08200	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FC605_RS08205	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
FC605_RS08210	COG2001	Belongs to the MraZ family
FC605_RS08215	COG0275	rRNA processing
FC605_RS08220	COG4839	cell division protein FtsL
FC605_RS08225	COG0768	penicillin binding
FC605_RS08230	COG0768	penicillin binding
FC605_RS08235	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FC605_RS08240	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FC605_RS08245	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FC605_RS08250	COG0772	Belongs to the SEDS family
FC605_RS08255	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FC605_RS08260	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FC605_RS08265	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FC605_RS08270	COG3879	Bacterial protein of unknown function (DUF881)
FC605_RS08275	COG3879	Bacterial protein of unknown function (DUF881)
FC605_RS08280	COG3856	small basic protein
FC605_RS08285	COG0849	cell division
FC605_RS08290	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FC605_RS08295	COG1404	Belongs to the peptidase S8 family
FC605_RS08295	COG4412	M6 family metalloprotease domain protein
FC605_RS08305	COG1191	sigma factor activity
FC605_RS08310	COG1191	sigma factor activity
FC605_RS08315	COG1119	ATPase activity
FC605_RS08320	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FC605_RS08325	COG1873	PFAM PRC-barrel domain
FC605_RS08330	COG1496	oxidoreductase activity
FC605_RS08335	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FC605_RS08340	COG1799	cell septum assembly
FC605_RS08345	COG0762	integral membrane protein
FC605_RS08350	COG2302	S4 RNA-binding domain
FC605_RS08355	COG3599	regulation of cell shape
FC605_RS08360	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FC605_RS08365	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FC605_RS08370	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FC605_RS08375	COG0564	pseudouridine synthase activity
FC605_RS08380	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FC605_RS08385	COG2233	PERMEase
FC605_RS08390	COG0540	Belongs to the ATCase OTCase family
FC605_RS08395	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FC605_RS08400	COG0505	Belongs to the CarA family
FC605_RS08405	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FC605_RS08410	COG0543	2 iron, 2 sulfur cluster binding
FC605_RS08415	COG0167	dihydroorotate dehydrogenase activity
FC605_RS08420	COG0284	orotidine-5'-phosphate decarboxylase activity
FC605_RS08425	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FC605_RS08430	COG0175	sulfate reduction
FC605_RS08435	COG0306	phosphate transporter
FC605_RS08440	COG2046	Belongs to the sulfate adenylyltransferase family
FC605_RS08445	COG0529	Catalyzes the synthesis of activated sulfate
FC605_RS08450	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FC605_RS08455	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
FC605_RS08460	COG1648	precorrin-2 dehydrogenase activity
FC605_RS08465	COG1293	RNA-binding protein homologous to eukaryotic snRNP
FC605_RS08470	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FC605_RS08475	COG1561	YicC-like family, N-terminal region
FC605_RS08485	COG0194	GDP metabolic process
FC605_RS08490	COG1758	RNA polymerase activity
FC605_RS08495	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FC605_RS08500	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FC605_RS08505	COG0242	peptide deformylase activity
FC605_RS08510	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FC605_RS08515	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FC605_RS08515	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FC605_RS08520	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FC605_RS08525	COG0631	protein serine/threonine phosphatase activity
FC605_RS08530	COG2815	serine threonine protein kinase
FC605_RS08530	COG0515	serine threonine protein kinase
FC605_RS08535	COG1162	GTPase activity
FC605_RS08540	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FC605_RS08545	COG1564	THIamine pyrophosphokinase
FC605_RS08555	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FC605_RS08560	COG1302	Protein conserved in bacteria
FC605_RS08565	COG1461	Dihydroxyacetone kinase
FC605_RS08570	COG1760	l-serine dehydratase
FC605_RS08575	COG1760	l-serine dehydratase
FC605_RS08580	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FC605_RS08585	COG2050	protein possibly involved in aromatic compounds catabolism
FC605_RS08585	COG1349	DNA-binding transcription factor activity
FC605_RS08590	COG0416	fatty acid biosynthetic process
FC605_RS08595	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FC605_RS08600	COG1028	Short-chain dehydrogenase reductase Sdr
FC605_RS08610	COG0571	ribonuclease III activity
FC605_RS08620	COG0552	protein localization to endoplasmic reticulum
FC605_RS08630	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
FC605_RS08635	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FC605_RS08640	COG0228	four-way junction DNA binding
FC605_RS08645	COG1837	Belongs to the UPF0109 family
FC605_RS08655	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FC605_RS08660	COG0336	Belongs to the RNA methyltransferase TrmD family
FC605_RS08665	COG0335	large ribosomal subunit rRNA binding
FC605_RS08670	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FC605_RS08675	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FC605_RS08685	COG2257	FlhB HrpN YscU SpaS Family
FC605_RS08690	COG0045	succinate-CoA ligase (ADP-forming) activity
FC605_RS08695	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FC605_RS08700	COG0758	DNA mediated transformation
FC605_RS08705	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FC605_RS08710	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FC605_RS08715	COG4974	Belongs to the 'phage' integrase family
FC605_RS08720	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FC605_RS08725	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FC605_RS08730	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FC605_RS08735	COG1815	bacterial-type flagellum-dependent cell motility
FC605_RS08740	COG1558	bacterial-type flagellum-dependent cell motility
FC605_RS08745	COG1677	Flagellar hook-basal body complex protein FliE
FC605_RS08750	COG1766	The M ring may be actively involved in energy transduction
FC605_RS08755	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FC605_RS08760	COG1317	bacterial-type flagellum organization
FC605_RS08765	COG1157	protein secretion by the type III secretion system
FC605_RS08770	COG2882	bacterial-type flagellum organization
FC605_RS08775	COG3334	PFAM MgtE intracellular
FC605_RS08780	COG3144	bacterial-type flagellum assembly
FC605_RS08785	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FC605_RS08790	COG4786	Flagellar basal body rod
FC605_RS08795	COG1582	Flagellar protein (FlbD)
FC605_RS08800	COG1580	Controls the rotational direction of flagella during chemotaxis
FC605_RS08805	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FC605_RS08810	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FC605_RS08810	COG1776	CheC inhibitor of MCP methylation
FC605_RS08815	COG2201	protein-glutamate methylesterase activity
FC605_RS08820	COG3190	flagellar
FC605_RS08825	COG1338	Plays a role in the flagellum-specific transport system
FC605_RS08830	COG1987	bacterial-type flagellum assembly
FC605_RS08835	COG1684	flagellar biosynthetic protein fliR
FC605_RS08840	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FC605_RS08845	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FC605_RS08850	COG1419	protein localization to endoplasmic reticulum
FC605_RS08855	COG0455	bacterial-type flagellum organization
FC605_RS08860	COG2201	protein-glutamate methylesterase activity
FC605_RS08865	COG2198	Histidine kinase
FC605_RS08865	COG0643	Histidine kinase
FC605_RS08870	COG0835	chemotaxis
FC605_RS08875	COG1776	CheC inhibitor of MCP methylation
FC605_RS08880	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FC605_RS08885	COG1191	sigma factor activity
FC605_RS08895	COG0052	Belongs to the universal ribosomal protein uS2 family
FC605_RS08900	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FC605_RS08905	COG0528	UMP kinase activity
FC605_RS08910	COG0233	cytoplasmic translational termination
FC605_RS08915	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FC605_RS08920	COG4589	Belongs to the CDS family
FC605_RS08925	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FC605_RS08930	COG0750	zinc metalloprotease
FC605_RS08935	COG0442	prolyl-tRNA aminoacylation
FC605_RS08940	COG2176	DNA-directed DNA polymerase activity
FC605_RS08945	COG0779	Required for maturation of 30S ribosomal subunits
FC605_RS08950	COG0195	Participates in both transcription termination and antitermination
FC605_RS08955	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FC605_RS08960	COG1358	cellular component organization or biogenesis
FC605_RS08965	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FC605_RS08970	COG1550	Protein conserved in bacteria
FC605_RS08975	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FC605_RS08980	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FC605_RS08985	COG0196	riboflavin kinase activity
FC605_RS08990	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FC605_RS08995	COG1185	polyribonucleotide nucleotidyltransferase activity
FC605_RS09000	COG0726	polysaccharide deacetylase
FC605_RS09005	COG0612	Peptidase, M16
FC605_RS09010	COG1873	PFAM PRC-barrel domain
FC605_RS09015	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FC605_RS09020	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FC605_RS09025	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FC605_RS09030	COG0527	aspartate kinase activity
FC605_RS09035	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FC605_RS09040	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FC605_RS09045	COG0740	serine-type endopeptidase activity
FC605_RS09055	COG4980	gas vesicle protein
FC605_RS09055	COG1674	ftsk spoiiie
FC605_RS09060	COG2188	Transcriptional regulator
FC605_RS09065	COG2814	Major facilitator Superfamily
FC605_RS09070	COG0612	Peptidase, M16
FC605_RS09075	COG0612	Peptidase, M16
FC605_RS09080	COG0300	oxidoreductase activity
FC605_RS09095	COG1426	Protein conserved in bacteria
FC605_RS09100	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FC605_RS09105	COG1546	Belongs to the CinA family
FC605_RS09105	COG1058	Belongs to the CinA family
FC605_RS09110	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FC605_RS09115	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FC605_RS09120	COG1418	mRNA catabolic process
FC605_RS09125	COG1692	metallophosphoesterase
FC605_RS09130	COG2359	stage V sporulation protein S
FC605_RS09135	COG1063	alcohol dehydrogenase
FC605_RS09140	COG0156	8-amino-7-oxononanoate synthase activity
FC605_RS09145	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FC605_RS09150	COG4550	Control of competence regulator ComK, YlbF/YmcA
FC605_RS09160	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FC605_RS09165	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FC605_RS09180	COG3226	Transcriptional regulator
FC605_RS09185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FC605_RS09195	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FC605_RS09200	COG3321	synthase
FC605_RS09205	COG2070	2-Nitropropane dioxygenase
FC605_RS09205	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FC605_RS09210	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FC605_RS09215	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FC605_RS09220	COG3425	synthase
FC605_RS09225	COG1024	Enoyl-CoA hydratase
FC605_RS09230	COG1024	Enoyl-CoA hydratase
FC605_RS09235	COG3321	synthase
FC605_RS09235	COG0300	oxidoreductase activity
FC605_RS09235	COG1028	Short-chain dehydrogenase reductase Sdr
FC605_RS09235	COG0318	PFAM AMP-dependent synthetase and ligase
FC605_RS09235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FC605_RS09250	COG3321	synthase
FC605_RS09250	COG1028	Short-chain dehydrogenase reductase Sdr
FC605_RS09250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FC605_RS09250	COG4221	oxidoreductase activity
FC605_RS09255	COG3321	synthase
FC605_RS09255	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FC605_RS09255	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FC605_RS09255	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FC605_RS09260	COG2124	cytochrome p450
FC605_RS09270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FC605_RS09275	COG1404	Belongs to the peptidase S8 family
FC605_RS09285	COG4195	phage-related replication protein
FC605_RS09290	COG1764	response to oxidative stress
FC605_RS09295	COG2076	Multidrug Resistance protein
FC605_RS09300	COG2076	Multidrug Resistance protein
FC605_RS09315	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FC605_RS09320	COG1923	regulation of RNA biosynthetic process
FC605_RS09335	COG1780	Probably involved in ribonucleotide reductase function
FC605_RS09340	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FC605_RS09345	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FC605_RS09350	COG4112	unkown
FC605_RS09355	COG0860	N-Acetylmuramoyl-L-alanine amidase
FC605_RS09365	COG0464	growth
FC605_RS09370	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FC605_RS09375	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FC605_RS09380	COG0789	Transcriptional regulator
FC605_RS09385	COG0174	glutamine synthetase
FC605_RS09420	COG0463	Glycosyl transferase, family 2
FC605_RS09435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FC605_RS09460	COG0135	phosphoribosylanthranilate isomerase activity
FC605_RS09465	COG2211	Major facilitator Superfamily
FC605_RS09470	COG3507	Belongs to the glycosyl hydrolase 43 family
FC605_RS09475	COG1940	carbohydrate kinase activity
FC605_RS09480	COG2115	Belongs to the xylose isomerase family
FC605_RS09485	COG1070	Carbohydrate kinase
FC605_RS09495	COG1525	nuclease
FC605_RS09500	COG2814	Major facilitator Superfamily
FC605_RS09505	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FC605_RS09515	COG0756	dUTP diphosphatase activity
FC605_RS09530	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FC605_RS09560	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FC605_RS09570	COG3832	glyoxalase III activity
FC605_RS09580	COG0697	spore germination
FC605_RS09585	COG0531	amino acid
FC605_RS09615	COG4195	phage-related replication protein
FC605_RS09625	COG0346	lactoylglutathione lyase activity
FC605_RS09635	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FC605_RS09640	COG1388	LysM domain
FC605_RS09645	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FC605_RS09650	COG4224	UPF0291 protein
FC605_RS09655	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FC605_RS09665	COG3763	UPF0154 protein
FC605_RS09675	COG0785	Cytochrome C biogenesis protein
FC605_RS09680	COG2201	protein-glutamate methylesterase activity
FC605_RS09685	COG4846	Membrane protein involved in cytochrome C biogenesis
FC605_RS09695	COG0071	Belongs to the small heat shock protein (HSP20) family
FC605_RS09710	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FC605_RS09715	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FC605_RS09735	COG0824	Thioesterase
FC605_RS09745	COG4841	protein insertion into membrane
FC605_RS09750	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FC605_RS09755	COG1832	CoA-binding protein
FC605_RS09760	COG0187	DNA topoisomerase II activity
FC605_RS09765	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FC605_RS09775	COG1115	amino acid carrier protein
FC605_RS09780	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FC605_RS09790	COG5520	Belongs to the glycosyl hydrolase 30 family
FC605_RS09795	COG3507	Belongs to the glycosyl hydrolase 43 family
FC605_RS09805	COG2246	polysaccharide biosynthetic process
FC605_RS09810	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FC605_RS09815	COG0586	Pfam SNARE associated Golgi protein
FC605_RS09820	COG2404	hydrolase activity, acting on ester bonds
FC605_RS09825	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FC605_RS09830	COG1024	Enoyl-CoA hydratase
FC605_RS09835	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FC605_RS09840	COG0511	ligase activity, forming carbon-carbon bonds
FC605_RS09845	COG0439	Biotin carboxylase
FC605_RS09850	COG0318	PFAM AMP-dependent synthetase and ligase
FC605_RS09855	COG1960	acyl-CoA dehydrogenase activity
FC605_RS09870	COG1649	PFAM Uncharacterised BCR, COG1649
FC605_RS09880	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FC605_RS09880	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FC605_RS09885	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FC605_RS09890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FC605_RS09895	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FC605_RS09900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FC605_RS09905	COG2027	D-alanyl-D-alanine carboxypeptidase
FC605_RS09910	COG2017	converts alpha-aldose to the beta-anomer
FC605_RS09930	COG0582	viral genome integration into host DNA
FC605_RS09935	COG0166	Belongs to the GPI family
FC605_RS09940	COG0405	Gamma-glutamyltransferase
FC605_RS09945	COG0583	DNA-binding transcription factor activity
FC605_RS09950	COG0604	alcohol dehydrogenase
FC605_RS09955	COG0493	'glutamate synthase
FC605_RS09960	COG0069	glutamate synthase activity
FC605_RS09960	COG0070	glutamate synthase
FC605_RS09960	COG0067	glutamate synthase
FC605_RS09965	COG0583	DNA-binding transcription factor activity
FC605_RS09970	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FC605_RS09975	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FC605_RS09985	COG0300	oxidoreductase activity
FC605_RS09990	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
FC605_RS10000	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FC605_RS10005	COG2814	Major facilitator Superfamily
FC605_RS10010	COG1070	Carbohydrate kinase
FC605_RS10015	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FC605_RS10020	COG0243	molybdopterin cofactor binding
FC605_RS10045	COG0840	transmembrane signaling receptor activity
FC605_RS10045	COG5278	phosphoserine phosphatase activity
FC605_RS10050	COG2368	4-hydroxyphenylacetate
FC605_RS10055	COG4305	rare lipoprotein A
FC605_RS10060	COG3619	membrane
FC605_RS10070	COG2135	peptidase activity
FC605_RS10080	COG2140	Oxalate decarboxylase
FC605_RS10095	COG0456	acetyltransferase
FC605_RS10115	COG2720	vancomycin resistance protein
FC605_RS10125	COG3655	Transcriptional regulator
FC605_RS10130	COG3739	integral membrane protein
FC605_RS10135	COG0583	DNA-binding transcription factor activity
FC605_RS10140	COG0697	spore germination
FC605_RS10150	COG0693	protein deglycase activity
FC605_RS10155	COG2367	Beta-lactamase
FC605_RS10180	COG0574	Belongs to the PEP-utilizing enzyme family
FC605_RS10180	COG3848	Pyruvate phosphate dikinase
FC605_RS10185	COG0726	polysaccharide deacetylase
FC605_RS10195	COG2314	TM2 domain
FC605_RS10200	COG1396	sequence-specific DNA binding
FC605_RS10235	COG1793	dna ligase
FC605_RS10275	COG1388	LysM domain
FC605_RS10305	COG0457	Tetratricopeptide repeat
FC605_RS10340	COG0457	Tetratricopeptide repeat
FC605_RS10355	COG5444	nuclease activity
FC605_RS10360	COG4282	regulation of fungal-type cell wall biogenesis
FC605_RS10365	COG1231	oxidoreductase activity
FC605_RS10370	COG5434	Belongs to the glycosyl hydrolase 28 family
FC605_RS10375	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FC605_RS10380	COG2207	Transcriptional regulator
FC605_RS10380	COG0662	Cupin 2, conserved barrel domain protein
FC605_RS10385	COG0456	acetyltransferase
FC605_RS10390	COG1309	transcriptional regulator
FC605_RS10395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FC605_RS10400	COG3708	Transcriptional regulator
FC605_RS10405	COG2378	regulation of single-species biofilm formation
FC605_RS10415	COG0640	Transcriptional regulator
FC605_RS10420	COG0741	lytic transglycosylase activity
FC605_RS10425	COG2322	membrane
FC605_RS10445	COG3239	Fatty acid desaturase
FC605_RS10450	COG4585	Histidine kinase
FC605_RS10455	COG2197	response regulator
FC605_RS10460	COG3584	3D domain protein
FC605_RS10460	COG1388	LysM domain
FC605_RS10465	COG0514	ATP-dependent DNA helicase (RecQ)
FC605_RS10475	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FC605_RS10480	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FC605_RS10495	COG0071	Belongs to the small heat shock protein (HSP20) family
FC605_RS10520	COG1012	belongs to the aldehyde dehydrogenase family
FC605_RS10525	COG1657	PFAM Prenyltransferase squalene oxidase
FC605_RS10530	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FC605_RS10535	COG0733	neurotransmitter:sodium symporter activity
FC605_RS10540	COG0385	Bile acid
FC605_RS10545	COG0508	dehydrogenase complex catalyzes the overall conversion of
FC605_RS10550	COG0567	Dehydrogenase, E1 component
FC605_RS10555	COG4548	von Willebrand factor, type A
FC605_RS10560	COG0714	Associated with various cellular activities
FC605_RS10565	COG2032	superoxide dismutase activity
FC605_RS10570	COG1388	LysM domain
FC605_RS10570	COG0791	NLP P60 protein
FC605_RS10575	COG1819	glycosyl
FC605_RS10580	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FC605_RS10585	COG0534	Mate efflux family protein
FC605_RS10590	COG1366	Belongs to the anti-sigma-factor antagonist family
FC605_RS10595	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FC605_RS10600	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FC605_RS10610	COG2962	Rard protein
FC605_RS10625	COG2610	gluconate transmembrane transporter activity
FC605_RS10630	COG1942	4-Oxalocrotonate Tautomerase
FC605_RS10635	COG1733	regulation of RNA biosynthetic process
FC605_RS10640	COG0778	Nitroreductase
FC605_RS10645	COG0400	carboxylic ester hydrolase activity
FC605_RS10650	COG0346	lactoylglutathione lyase activity
FC605_RS10660	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FC605_RS10665	COG3409	Peptidoglycan-binding domain 1 protein
FC605_RS10665	COG0793	Belongs to the peptidase S41A family
FC605_RS10670	COG2226	methyltransferase
FC605_RS10680	COG1876	peptidase activity
FC605_RS10685	COG0813	purine-nucleoside phosphorylase activity
FC605_RS10700	COG0671	phosphoesterase, PA-phosphatase related
FC605_RS10725	COG4479	Belongs to the UPF0346 family
FC605_RS10735	COG1509	lysine 2,3-aminomutase activity
FC605_RS10740	COG0456	acetyltransferase
FC605_RS10745	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FC605_RS10750	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FC605_RS10755	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FC605_RS10760	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FC605_RS10775	COG0456	acetyltransferase
FC605_RS10780	COG0463	Glycosyl transferase, family 2
FC605_RS10795	COG4641	Protein conserved in bacteria
FC605_RS10800	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
FC605_RS10805	COG1086	Polysaccharide biosynthesis protein
FC605_RS10810	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FC605_RS10815	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FC605_RS10820	COG1846	Transcriptional regulator
FC605_RS10825	COG0534	Mate efflux family protein
FC605_RS10835	COG4698	Protein conserved in bacteria
FC605_RS10840	COG2755	lipolytic protein G-D-S-L family
FC605_RS10845	COG1999	signal sequence binding
FC605_RS10855	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FC605_RS10860	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FC605_RS10865	COG1272	protein, Hemolysin III
FC605_RS10870	COG0204	Acyl-transferase
FC605_RS10875	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FC605_RS10880	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FC605_RS10885	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FC605_RS10895	COG2521	methyltransferase
FC605_RS10895	COG2136	Putative SAM-dependent methyltransferase
FC605_RS10905	COG0129	dihydroxy-acid dehydratase activity
FC605_RS10910	COG1413	lyase activity
FC605_RS10915	COG1418	mRNA catabolic process
FC605_RS10920	COG0386	Belongs to the glutathione peroxidase family
FC605_RS10925	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FC605_RS10930	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FC605_RS10940	COG1278	Cold shock
FC605_RS10960	COG0328	RNA-DNA hybrid ribonuclease activity
FC605_RS10965	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FC605_RS10970	COG0328	RNA-DNA hybrid ribonuclease activity
FC605_RS10980	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FC605_RS10995	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FC605_RS11005	COG1755	Isoprenylcysteine carboxyl methyltransferase
FC605_RS11010	COG3424	synthase
FC605_RS11015	COG2233	PERMEase
FC605_RS11020	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FC605_RS11035	COG0800	Aldolase
FC605_RS11040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FC605_RS11045	COG1609	Transcriptional regulator
FC605_RS11050	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FC605_RS11055	COG1028	Short-chain dehydrogenase reductase Sdr
FC605_RS11060	COG1199	ATP-dependent helicase activity
FC605_RS11075	COG0116	Belongs to the methyltransferase superfamily
FC605_RS11090	COG4474	Belongs to the UPF0398 family
FC605_RS11105	COG3359	exonuclease
FC605_RS11110	COG1205	dead DEAH box helicase
FC605_RS11110	COG1111	helicase
FC605_RS11115	COG2190	(PTS) system
FC605_RS11120	COG0071	Belongs to the small heat shock protein (HSP20) family
FC605_RS11155	COG3331	DNA recombination
FC605_RS11160	COG4499	WXG100 protein secretion system (Wss), protein YukC
FC605_RS11160	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FC605_RS11170	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FC605_RS11175	COG3935	DnaD domain protein
FC605_RS11180	COG0017	Asparaginyl-tRNA synthetase
FC605_RS11185	COG0436	Aminotransferase
FC605_RS11190	COG5353	protein conserved in bacteria
FC605_RS11200	COG1199	ATP-dependent helicase activity
FC605_RS11200	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FC605_RS11205	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FC605_RS11210	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FC605_RS11215	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FC605_RS11220	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FC605_RS11220	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FC605_RS11225	COG0617	tRNA 3'-terminal CCA addition
FC605_RS11230	COG0438	transferase activity, transferring glycosyl groups
FC605_RS11235	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FC605_RS11240	COG1803	Methylglyoxal synthase
FC605_RS11245	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FC605_RS11250	COG1694	Mazg nucleotide pyrophosphohydrolase
FC605_RS11255	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FC605_RS11265	COG4347	Protein of unknown function (DUF1405)
FC605_RS11270	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FC605_RS11270	COG2010	Cytochrome c
FC605_RS11275	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FC605_RS11280	COG0723	plastoquinol--plastocyanin reductase activity
FC605_RS11290	COG5582	Belongs to the UPF0302 family
FC605_RS11295	COG0457	Tetratricopeptide repeat
FC605_RS11300	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FC605_RS11305	COG0287	Prephenate dehydrogenase
FC605_RS11320	COG0133	tryptophan synthase activity
FC605_RS11325	COG0135	phosphoribosylanthranilate isomerase activity
FC605_RS11335	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FC605_RS11340	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FC605_RS11345	COG4401	Chorismate mutase type I
FC605_RS11350	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FC605_RS11355	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FC605_RS11360	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FC605_RS11365	COG0105	UTP biosynthetic process
FC605_RS11370	COG0142	geranyltranstransferase activity
FC605_RS11375	COG2226	methyltransferase
FC605_RS11380	COG0142	geranyltranstransferase activity
FC605_RS11390	COG0302	gtp cyclohydrolase
FC605_RS11395	COG0776	regulation of translation
FC605_RS11400	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FC605_RS11415	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FC605_RS11420	COG1160	GTP binding
FC605_RS11445	COG1304	FMN binding
FC605_RS11450	COG0539	negative regulation of cytoplasmic translation
FC605_RS11455	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FC605_RS11465	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
FC605_RS11470	COG2959	enzyme of heme biosynthesis
FC605_RS11475	COG3773	Cell wall hydrolase
FC605_RS11475	COG3409	Peptidoglycan-binding domain 1 protein
FC605_RS11480	COG2339	peptidase activity
FC605_RS11485	COG0492	ferredoxin-NADP+ reductase activity
FC605_RS11490	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FC605_RS11495	COG4862	establishment of competence for transformation
FC605_RS11500	COG1408	metallophosphoesterase
FC605_RS11510	COG1388	LysM domain
FC605_RS11515	COG1266	CAAX protease self-immunity
FC605_RS11520	COG0514	ATP-dependent DNA helicase (RecQ)
FC605_RS11525	COG4955	Helix-turn-helix domain
FC605_RS11530	COG1141	Ferredoxin
FC605_RS11535	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FC605_RS11540	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FC605_RS11545	COG0710	3-dehydroquinate dehydratase activity
FC605_RS11555	COG1595	DNA-templated transcription, initiation
FC605_RS11560	COG5002	protein histidine kinase activity
FC605_RS11565	COG0745	RESPONSE REGULATOR receiver
FC605_RS11570	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FC605_RS11575	COG1333	cytochrome c biogenesis protein
FC605_RS11580	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FC605_RS11585	COG1187	pseudouridine synthase activity
FC605_RS11590	COG0700	Nucleoside recognition
FC605_RS11595	COG2715	membrane protein required for spore maturation
FC605_RS11600	COG1686	Belongs to the peptidase S11 family
FC605_RS11610	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FC605_RS11615	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FC605_RS11620	COG1547	Domain of unknown function (DUF309)
FC605_RS11625	COG0456	acetyltransferase
FC605_RS11630	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FC605_RS11635	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FC605_RS11635	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FC605_RS11640	COG0307	riboflavin synthase, alpha
FC605_RS11645	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FC605_RS11645	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FC605_RS11655	COG0681	Belongs to the peptidase S26 family
FC605_RS11665	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
FC605_RS11745	COG0457	Tetratricopeptide repeat
FC605_RS11750	COG5444	nuclease activity
FC605_RS11790	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FC605_RS11805	COG4086	secreted protein
FC605_RS11810	COG0019	diaminopimelate decarboxylase activity
FC605_RS11815	COG0697	spore germination
FC605_RS11830	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FC605_RS11850	COG1191	sigma factor activity
FC605_RS11855	COG2172	sigma factor antagonist activity
FC605_RS11860	COG1366	Belongs to the anti-sigma-factor antagonist family
FC605_RS11865	COG1686	Belongs to the peptidase S11 family
FC605_RS11870	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FC605_RS11875	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FC605_RS11880	COG4974	Belongs to the 'phage' integrase family
FC605_RS11890	COG0735	belongs to the Fur family
FC605_RS11895	COG1300	Membrane
FC605_RS11905	COG0281	malic enzyme
FC605_RS11910	COG1757	Na H antiporter
FC605_RS11915	COG1027	Aspartate ammonia-lyase
FC605_RS11920	COG0252	asparaginase activity
FC605_RS11925	COG1396	sequence-specific DNA binding
FC605_RS11930	COG1379	DNA repair
FC605_RS11935	COG0494	nUDIX hydrolase
FC605_RS11945	COG0667	Aldo Keto reductase
FC605_RS11955	COG1073	alpha beta
FC605_RS11965	COG4918	Iron-sulphur cluster biosynthesis
FC605_RS11970	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FC605_RS11970	COG0456	acetyltransferase
FC605_RS11975	COG2329	Antibiotic biosynthesis monooxygenase
FC605_RS11980	COG0456	acetyltransferase
FC605_RS11990	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FC605_RS12000	COG2211	Major facilitator Superfamily
FC605_RS12005	COG0346	lactoylglutathione lyase activity
FC605_RS12010	COG1072	(Pantothenic acid kinase))
FC605_RS12015	COG3048	D-serine ammonia-lyase activity
FC605_RS12020	COG0300	oxidoreductase activity
FC605_RS12025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FC605_RS12030	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FC605_RS12035	COG4187	Peptidase family M20/M25/M40
FC605_RS12040	COG1902	pentaerythritol trinitrate reductase activity
FC605_RS12045	COG0596	Alpha beta hydrolase
FC605_RS12055	COG1234	tRNA 3'-trailer cleavage
FC605_RS12060	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FC605_RS12065	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FC605_RS12070	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FC605_RS12080	COG0706	membrane insertase activity
FC605_RS12085	COG3361	conserved protein (COG2071)
FC605_RS12090	COG2195	Cleaves the N-terminal amino acid of tripeptides
FC605_RS12095	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FC605_RS12100	COG0346	lactoylglutathione lyase activity
FC605_RS12105	COG1376	ErfK ybiS ycfS ynhG family protein
FC605_RS12110	COG4129	membrane
FC605_RS12115	COG1126	abc transporter atp-binding protein
FC605_RS12120	COG0765	amino acid transport
FC605_RS12125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FC605_RS12135	COG1597	lipid kinase activity
FC605_RS12140	COG2814	Major facilitator Superfamily
FC605_RS12145	COG4978	Transcriptional regulator
FC605_RS12145	COG0789	Transcriptional regulator
FC605_RS12150	COG0508	dehydrogenase complex catalyzes the overall conversion of
FC605_RS12155	COG0022	dehydrogenase e1 component
FC605_RS12160	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FC605_RS12165	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FC605_RS12170	COG3426	butyrate kinase activity
FC605_RS12175	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FC605_RS12180	COG0280	phosphate acetyltransferase
FC605_RS12185	COG3290	protein histidine kinase activity
FC605_RS12185	COG3829	transcription factor binding
FC605_RS12195	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FC605_RS12200	COG2079	MmgE PrpD family protein
FC605_RS12205	COG0372	Belongs to the citrate synthase family
FC605_RS12210	COG1960	acyl-CoA dehydrogenase activity
FC605_RS12215	COG1250	3-hydroxyacyl-CoA dehydrogenase
FC605_RS12220	COG0183	Belongs to the thiolase family
FC605_RS12225	COG0584	glycerophosphoryl diester phosphodiesterase
FC605_RS12230	COG0860	N-Acetylmuramoyl-L-alanine amidase
FC605_RS12245	COG1902	pentaerythritol trinitrate reductase activity
FC605_RS12250	COG0745	RESPONSE REGULATOR receiver
FC605_RS12255	COG0750	zinc metalloprotease
FC605_RS12260	COG0497	DNA recombination
FC605_RS12265	COG1438	arginine binding
FC605_RS12270	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FC605_RS12275	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FC605_RS12280	COG0142	geranyltranstransferase activity
FC605_RS12285	COG1722	exodeoxyribonuclease VII activity
FC605_RS12290	COG1570	exodeoxyribonuclease VII activity
FC605_RS12295	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FC605_RS12300	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FC605_RS12305	COG1302	Protein conserved in bacteria
FC605_RS12310	COG0439	Biotin carboxylase
FC605_RS12315	COG0511	ligase activity, forming carbon-carbon bonds
FC605_RS12355	COG3854	ATPases associated with a variety of cellular activities
FC605_RS12365	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FC605_RS12370	COG0006	proline dipeptidase activity
FC605_RS12375	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FC605_RS12385	COG3872	metal-dependent enzyme
FC605_RS12395	COG1752	Esterase of the alpha-beta hydrolase superfamily
FC605_RS12400	COG1321	iron dependent repressor
FC605_RS12405	COG0095	Lipoate-protein ligase
FC605_RS12410	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FC605_RS12415	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FC605_RS12420	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FC605_RS12425	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FC605_RS12430	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FC605_RS12445	COG1396	sequence-specific DNA binding
FC605_RS12455	COG0681	Belongs to the peptidase S26 family
FC605_RS12480	COG4940	Competence protein ComGF
FC605_RS12490	COG4970	Tfp pilus assembly protein FimT
FC605_RS12495	COG4537	Required for transformation and DNA binding
FC605_RS12500	COG1459	type II secretion system
FC605_RS12505	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FC605_RS12515	COG0598	Magnesium transport protein CorA
FC605_RS12520	COG1253	flavin adenine dinucleotide binding
FC605_RS12525	COG1366	Belongs to the anti-sigma-factor antagonist family
FC605_RS12535	COG1393	Belongs to the ArsC family
FC605_RS12545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FC605_RS12555	COG0011	TIGRFAM Protein of
FC605_RS12565	COG2866	Carboxypeptidase
FC605_RS12570	COG1368	sulfuric ester hydrolase activity
FC605_RS12575	COG1940	carbohydrate kinase activity
FC605_RS12580	COG4483	Protein conserved in bacteria
FC605_RS12585	COG0457	Tetratricopeptide repeat
FC605_RS12585	COG0705	Rhomboid family
FC605_RS12595	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FC605_RS12605	COG0438	transferase activity, transferring glycosyl groups
FC605_RS12620	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FC605_RS12625	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FC605_RS12630	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FC605_RS12635	COG0581	inorganic phosphate transmembrane transporter activity
FC605_RS12640	COG0573	inorganic phosphate transmembrane transporter activity
FC605_RS12645	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FC605_RS12650	COG0768	penicillin binding
FC605_RS12655	COG0477	Major facilitator Superfamily
FC605_RS12660	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FC605_RS12665	COG2839	Protein conserved in bacteria
FC605_RS12670	COG5521	maltodextrose utilization protein MalA
FC605_RS12675	COG1388	LysM domain
FC605_RS12680	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FC605_RS12685	COG4709	membrane
FC605_RS12690	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
FC605_RS12695	COG0735	belongs to the Fur family
FC605_RS12700	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FC605_RS12710	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FC605_RS12715	COG0513	Belongs to the DEAD box helicase family
FC605_RS12725	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FC605_RS12730	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FC605_RS12735	COG2384	SAM-dependent methyltransferase
FC605_RS12740	COG2010	Cytochrome c
FC605_RS12750	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FC605_RS12755	COG0358	DNA primase activity
FC605_RS12760	COG1671	Belongs to the UPF0178 family
FC605_RS12765	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FC605_RS12770	COG0517	IMP dehydrogenase activity
FC605_RS12775	COG0751	glycine-tRNA ligase activity
FC605_RS12780	COG0752	glycyl-tRNA synthetase alpha subunit
FC605_RS12785	COG1381	Involved in DNA repair and RecF pathway recombination
FC605_RS12795	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FC605_RS12800	COG0295	cytidine deaminase activity
FC605_RS12805	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FC605_RS12810	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FC605_RS12815	COG1480	7TM receptor with intracellular HD hydrolase
FC605_RS12820	COG1702	phosphate starvation-inducible protein PhoH
FC605_RS12825	COG0561	phosphatase activity
FC605_RS12840	COG4864	UPF0365 protein
FC605_RS12845	COG1030	water channel activity
FC605_RS12850	COG1610	YqeY-like protein
FC605_RS12860	COG1283	sodium-dependent phosphate transmembrane transporter activity
FC605_RS12865	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FC605_RS12870	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FC605_RS12875	COG2264	protein methyltransferase activity
FC605_RS12880	COG0484	heat shock protein binding
FC605_RS12885	COG0443	Heat shock 70 kDa protein
FC605_RS12890	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FC605_RS12895	COG1420	regulation of RNA biosynthetic process
FC605_RS12900	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FC605_RS12905	COG0481	GTPase activity
FC605_RS12915	COG0860	N-Acetylmuramoyl-L-alanine amidase
FC605_RS12920	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FC605_RS12925	COG0268	Binds directly to 16S ribosomal RNA
FC605_RS12930	COG1466	dna polymerase III delta subunit
FC605_RS12945	COG2333	competence protein COMEC
FC605_RS12945	COG0658	competence protein
FC605_RS12950	COG2131	deaminase
FC605_RS12955	COG1555	photosystem II stabilization
FC605_RS12955	COG1596	polysaccharide export
FC605_RS12960	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FC605_RS12965	COG2226	methyltransferase
FC605_RS12970	COG0799	negative regulation of ribosome biogenesis
FC605_RS12975	COG1713	HD superfamily hydrolase involved in NAD metabolism
FC605_RS12980	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FC605_RS12985	COG1534	Rna-binding protein
FC605_RS12990	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FC605_RS12995	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FC605_RS13000	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FC605_RS13010	COG2755	lipolytic protein G-D-S-L family
FC605_RS13015	COG5632	N-Acetylmuramoyl-L-alanine amidase
FC605_RS13015	COG3409	Peptidoglycan-binding domain 1 protein
FC605_RS13020	COG0398	Pfam SNARE associated Golgi protein
FC605_RS13025	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FC605_RS13035	COG3209	COG3209 Rhs family protein
FC605_RS13045	COG1846	Transcriptional regulator
FC605_RS13050	COG0477	Major facilitator Superfamily
FC605_RS13055	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FC605_RS13065	COG4124	Belongs to the glycosyl hydrolase 26 family
FC605_RS13075	COG2808	Putative FMN-binding domain
FC605_RS13080	COG0456	acetyltransferase
FC605_RS13085	COG1846	Transcriptional regulator
FC605_RS13090	COG2364	Membrane
FC605_RS13100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FC605_RS13105	COG0457	Tetratricopeptide repeat
FC605_RS13110	COG5444	nuclease activity
FC605_RS13120	COG5632	N-Acetylmuramoyl-L-alanine amidase
FC605_RS13120	COG3409	Peptidoglycan-binding domain 1 protein
FC605_RS13135	COG5484	DNA packaging
FC605_RS13155	COG3677	Transposase
FC605_RS13200	COG0563	adenylate kinase activity
FC605_RS13205	COG2856	Zn peptidase
FC605_RS13225	COG4124	Belongs to the glycosyl hydrolase 26 family
FC605_RS13230	COG0730	response to heat
FC605_RS13235	COG0425	Belongs to the sulfur carrier protein TusA family
FC605_RS13240	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FC605_RS13240	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FC605_RS13250	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FC605_RS13250	COG0425	Belongs to the sulfur carrier protein TusA family
FC605_RS13260	COG2210	Belongs to the sulfur carrier protein TusA family
FC605_RS13265	COG1937	Protein conserved in bacteria
FC605_RS13280	COG0662	Cupin 2, conserved barrel domain protein
FC605_RS13295	COG0789	Transcriptional regulator
FC605_RS13295	COG4978	Transcriptional regulator
FC605_RS13300	COG2814	Major facilitator Superfamily
FC605_RS13305	COG0456	acetyltransferase
FC605_RS13310	COG1253	flavin adenine dinucleotide binding
FC605_RS13320	COG0697	spore germination
FC605_RS13325	COG0583	DNA-binding transcription factor activity
FC605_RS13330	COG2072	flavoprotein involved in K transport
FC605_RS13335	COG1230	cation diffusion facilitator family transporter
FC605_RS13340	COG1942	4-Oxalocrotonate Tautomerase
FC605_RS13345	COG0583	DNA-binding transcription factor activity
FC605_RS13355	COG1114	Component of the transport system for branched-chain amino acids
FC605_RS13360	COG1687	branched-chain amino acid
FC605_RS13365	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FC605_RS13370	COG1522	sequence-specific DNA binding
FC605_RS13375	COG2732	(Barnase) inhibitor
FC605_RS13380	COG2124	cytochrome p450
FC605_RS13395	COG1335	isochorismatase
FC605_RS13410	COG2318	DinB family
FC605_RS13420	COG2070	2-Nitropropane dioxygenase
FC605_RS13435	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FC605_RS13455	COG3443	Belongs to the bacterial solute-binding protein 9 family
FC605_RS13460	COG1595	DNA-templated transcription, initiation
FC605_RS13465	COG0667	Aldo Keto reductase
FC605_RS13470	COG2851	Citrate transporter
FC605_RS13475	COG0583	DNA-binding transcription factor activity
FC605_RS13480	COG2828	Protein conserved in bacteria
FC605_RS13485	COG3409	Peptidoglycan-binding domain 1 protein
FC605_RS13490	COG5566	PFAM Mor transcription activator
FC605_RS13495	COG0596	Alpha beta hydrolase
FC605_RS13500	COG4991	sh3 domain protein
FC605_RS13505	COG4991	sh3 domain protein
FC605_RS13515	COG0346	lactoylglutathione lyase activity
FC605_RS13525	COG5577	PFAM Coat F domain
FC605_RS13530	COG1063	alcohol dehydrogenase
FC605_RS13540	COG5577	PFAM Coat F domain
FC605_RS13545	COG0789	Transcriptional regulator
FC605_RS13555	COG1064	alcohol dehydrogenase
FC605_RS13560	COG0693	protein deglycase activity
FC605_RS13565	COG1621	beta-fructofuranosidase activity
FC605_RS13570	COG3716	PTS system mannose fructose sorbose family IID component
FC605_RS13575	COG3715	PTS system
FC605_RS13580	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FC605_RS13585	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FC605_RS13590	COG3933	PFAM sigma-54 factor interaction domain-containing protein
FC605_RS13590	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FC605_RS13600	COG1113	amino acid transport
FC605_RS13605	COG1280	lysine exporter protein (LysE YggA)
FC605_RS13610	COG1378	Sugar-specific transcriptional regulator TrmB
FC605_RS13615	COG1595	DNA-templated transcription, initiation
FC605_RS13625	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FC605_RS13625	COG2755	lipolytic protein G-D-S-L family
FC605_RS13635	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FC605_RS13635	COG2124	cytochrome p450
FC605_RS13640	COG1309	transcriptional regulator
FC605_RS13645	COG2226	methyltransferase
FC605_RS13660	COG2116	formate transmembrane transporter activity
FC605_RS13665	COG5609	conserved protein (DUF2294)
FC605_RS13670	COG3383	formate dehydrogenase (NAD+) activity
FC605_RS13675	COG2427	Protein of unknown function (DUF1641)
FC605_RS13685	COG0626	cystathionine gamma-synthase activity
FC605_RS13690	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FC605_RS13695	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FC605_RS13700	COG2226	methyltransferase
FC605_RS13715	COG0768	penicillin binding
FC605_RS13720	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FC605_RS13725	COG0572	uridine kinase
FC605_RS13730	COG0826	peptidase U32
FC605_RS13735	COG0826	peptidase U32
FC605_RS13740	COG4122	O-methyltransferase activity
FC605_RS13745	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FC605_RS13750	COG3906	Belongs to the UPF0473 family
FC605_RS13755	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FC605_RS13760	COG4472	Bacterial protein of unknown function (DUF965)
FC605_RS13765	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FC605_RS13770	COG0628	permease
FC605_RS13775	COG1126	abc transporter atp-binding protein
FC605_RS13780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FC605_RS13785	COG0765	amino acid transport
FC605_RS13790	COG0765	amino acid transport
FC605_RS13805	COG3881	PFAM PRC-barrel domain
FC605_RS13810	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FC605_RS13815	COG0457	Tetratricopeptide repeat
FC605_RS13820	COG0482	sulfurtransferase activity
FC605_RS13825	COG1104	cysteine desulfurase activity
FC605_RS13830	COG1959	2 iron, 2 sulfur cluster binding
FC605_RS13835	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FC605_RS13840	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FC605_RS13850	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FC605_RS13855	COG0124	histidyl-tRNA synthetase
FC605_RS13865	COG0860	N-Acetylmuramoyl-L-alanine amidase
FC605_RS13865	COG3103	Sh3 type 3 domain protein
FC605_RS13865	COG4991	sh3 domain protein
FC605_RS13870	COG1490	D-aminoacyl-tRNA deacylase activity
FC605_RS13875	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FC605_RS13880	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FC605_RS13885	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FC605_RS13885	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FC605_RS13890	COG5416	Lipopolysaccharide assembly protein A domain
FC605_RS13895	COG0490	domain, Protein
FC605_RS13900	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FC605_RS13900	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FC605_RS13910	COG2244	polysaccharide biosynthetic process
FC605_RS13915	COG2323	membrane
FC605_RS13925	COG1862	Preprotein translocase
FC605_RS13930	COG0343	queuine tRNA-ribosyltransferase activity
FC605_RS13935	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FC605_RS13945	COG2255	four-way junction helicase activity
FC605_RS13950	COG0632	four-way junction helicase activity
FC605_RS13960	COG2814	Major facilitator Superfamily
FC605_RS13965	COG0673	inositol 2-dehydrogenase activity
FC605_RS13970	COG2112	serine threonine protein kinase
FC605_RS13990	COG1115	amino acid carrier protein
FC605_RS13995	COG0217	transcriptional regulatory protein
FC605_RS14005	COG1388	LysM domain
FC605_RS14010	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FC605_RS14015	COG0157	Belongs to the NadC ModD family
FC605_RS14020	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FC605_RS14025	COG1104	cysteine desulfurase activity
FC605_RS14030	COG1827	regulation of RNA biosynthetic process
FC605_RS14035	COG0077	Prephenate dehydratase
FC605_RS14040	COG4492	Belongs to the UPF0735 family
FC605_RS14045	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FC605_RS14050	COG3290	protein histidine kinase activity
FC605_RS14060	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FC605_RS14065	COG2868	ribosomal protein
FC605_RS14070	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FC605_RS14075	COG1994	Peptidase M50
FC605_RS14080	COG0739	heme binding
FC605_RS14085	COG2894	cell division
FC605_RS14090	COG0850	regulation of cytokinetic process
FC605_RS14095	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FC605_RS14105	COG1077	Cell shape determining protein MreB Mrl
FC605_RS14110	COG2003	Belongs to the UPF0758 family
FC605_RS14115	COG0424	maF-like protein
FC605_RS14125	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FC605_RS14130	COG0285	dihydrofolate synthase activity
FC605_RS14135	COG0525	valine-tRNA ligase activity
FC605_RS14145	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FC605_RS14150	COG1388	LysM domain
FC605_RS14155	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FC605_RS14160	COG0113	porphobilinogen synthase activity
FC605_RS14165	COG1587	Uroporphyrinogen-III synthase
FC605_RS14170	COG0181	hydroxymethylbilane synthase activity
FC605_RS14175	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FC605_RS14180	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FC605_RS14190	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FC605_RS14195	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FC605_RS14205	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FC605_RS14210	COG0544	peptidyl-prolyl cis-trans isomerase activity
FC605_RS14215	COG0457	Tetratricopeptide repeat
FC605_RS14215	COG1477	protein flavinylation
FC605_RS14220	COG0066	3-isopropylmalate dehydratase activity
FC605_RS14225	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FC605_RS14230	COG0473	3-isopropylmalate dehydrogenase activity
FC605_RS14235	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FC605_RS14240	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FC605_RS14245	COG0440	acetolactate synthase activity
FC605_RS14250	COG0028	Belongs to the TPP enzyme family
FC605_RS14260	COG0454	-acetyltransferase
FC605_RS14265	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
FC605_RS14275	COG0622	Phosphoesterase
FC605_RS14280	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FC605_RS14285	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FC605_RS14290	COG5401	PFAM Sporulation and spore germination
FC605_RS14295	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FC605_RS14300	COG1846	Transcriptional regulator
FC605_RS14305	COG2197	response regulator
FC605_RS14310	COG0824	Thioesterase
FC605_RS14315	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FC605_RS14320	COG1053	succinate dehydrogenase
FC605_RS14325	COG2009	succinate dehydrogenase
FC605_RS14330	COG1719	4-vinyl reductase, 4VR
FC605_RS14335	COG0527	aspartate kinase activity
FC605_RS14345	COG0322	excinuclease ABC activity
FC605_RS14350	COG3118	belongs to the thioredoxin family
FC605_RS14360	COG3534	alpha-L-arabinofuranosidase
FC605_RS14365	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FC605_RS14370	COG2086	electron transfer activity
FC605_RS14375	COG1024	Enoyl-CoA hydratase
FC605_RS14380	COG1309	transcriptional regulator
FC605_RS14385	COG0318	PFAM AMP-dependent synthetase and ligase
FC605_RS14390	COG3766	membrane
FC605_RS14395	COG1193	negative regulation of DNA recombination
FC605_RS14400	COG1796	DNA polymerase
FC605_RS14400	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FC605_RS14405	COG1286	toxin biosynthetic process
FC605_RS14410	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FC605_RS14415	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FC605_RS14420	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FC605_RS14420	COG0072	phenylalanine-tRNA ligase activity
FC605_RS14425	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FC605_RS14435	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FC605_RS14445	COG3835	regulator
FC605_RS14450	COG0277	FAD linked oxidase domain protein
FC605_RS14455	COG0247	lactate metabolic process
FC605_RS14460	COG0346	lactoylglutathione lyase activity
FC605_RS14470	COG1966	Carbon starvation protein
FC605_RS14475	COG3534	alpha-L-arabinofuranosidase
FC605_RS14480	COG0395	ABC-type sugar transport system, permease component
FC605_RS14485	COG1175	transmembrane transport
FC605_RS14490	COG1653	transport
FC605_RS14495	COG0371	Dehydrogenase
FC605_RS14500	COG0647	UMP catabolic process
FC605_RS14505	COG0235	Class ii aldolase
FC605_RS14510	COG1069	ribulokinase activity
FC605_RS14515	COG2160	L-arabinose isomerase activity
FC605_RS14520	COG3507	Belongs to the glycosyl hydrolase 43 family
FC605_RS14525	COG1363	Peptidase, m42
FC605_RS14535	COG3326	Membrane
FC605_RS14540	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FC605_RS14545	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FC605_RS14550	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FC605_RS14560	COG1346	cytolysis
FC605_RS14565	COG1380	Effector of murein hydrolase LrgA
FC605_RS14570	COG3279	Response regulator of the LytR AlgR family
FC605_RS14575	COG3275	phosphorelay sensor kinase activity
FC605_RS14580	COG1011	Hydrolase
FC605_RS14585	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FC605_RS14595	COG0398	Pfam SNARE associated Golgi protein
FC605_RS14600	COG1484	DNA-dependent DNA replication
FC605_RS14605	COG3611	Membrane attachment protein
FC605_RS14610	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FC605_RS14615	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FC605_RS14620	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FC605_RS14630	COG2814	Major facilitator Superfamily
FC605_RS14635	COG0656	L-ascorbic acid biosynthetic process
FC605_RS14640	COG0237	dephospho-CoA kinase activity
FC605_RS14645	COG1971	Probably functions as a manganese efflux pump
FC605_RS14650	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FC605_RS14655	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FC605_RS14655	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FC605_RS14660	COG5002	protein histidine kinase activity
FC605_RS14665	COG0745	RESPONSE REGULATOR receiver
FC605_RS14670	COG0039	L-malate dehydrogenase activity
FC605_RS14675	COG0538	isocitrate dehydrogenase activity
FC605_RS14680	COG0372	Belongs to the citrate synthase family
FC605_RS14685	COG2707	UPF0756 membrane protein
FC605_RS14690	COG0628	permease
FC605_RS14695	COG3030	protein affecting phage T7 exclusion by the F plasmid
FC605_RS14700	COG0469	pyruvate kinase activity
FC605_RS14705	COG0205	6-phosphofructokinase activity
FC605_RS14710	COG0825	malonyl-CoA metabolic process
FC605_RS14715	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FC605_RS14720	COG0281	malic enzyme
FC605_RS14725	COG0587	DNA-directed DNA polymerase activity
FC605_RS14745	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FC605_RS14755	COG4109	DRTGG domain
FC605_RS14760	COG0730	response to heat
FC605_RS14765	COG1473	amidohydrolase
FC605_RS14770	COG0196	riboflavin kinase activity
FC605_RS14775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FC605_RS14780	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FC605_RS14785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FC605_RS14790	COG1126	abc transporter atp-binding protein
FC605_RS14795	COG0765	amino acid transport
FC605_RS14800	COG0765	amino acid transport
FC605_RS14805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FC605_RS14810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FC605_RS14815	COG0454	-acetyltransferase
FC605_RS14820	COG0583	DNA-binding transcription factor activity
FC605_RS14825	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FC605_RS14830	COG1028	Short-chain dehydrogenase reductase Sdr
FC605_RS14835	COG0165	Argininosuccinate lyase
FC605_RS14840	COG0137	argininosuccinate synthase activity
FC605_RS14845	COG0521	Mo-molybdopterin cofactor biosynthetic process
FC605_RS14850	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FC605_RS14860	COG0827	DNA restriction-modification system
FC605_RS14865	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FC605_RS14870	COG3874	Sporulation protein YtfJ
FC605_RS14880	COG1714	RDD family
FC605_RS14885	COG0616	signal peptide processing
FC605_RS14890	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FC605_RS14895	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FC605_RS14910	COG0301	tRNA thio-modification
FC605_RS14915	COG1104	cysteine desulfurase activity
FC605_RS14920	COG1114	Component of the transport system for branched-chain amino acids
FC605_RS14925	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
FC605_RS14930	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FC605_RS14935	COG1309	transcriptional regulator
FC605_RS14940	COG1956	GAF domain-containing protein
FC605_RS14945	COG2199	diguanylate cyclase activity
FC605_RS14945	COG2203	Gaf domain
FC605_RS14955	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FC605_RS14960	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FC605_RS14965	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FC605_RS14970	COG0454	-acetyltransferase
FC605_RS14975	COG0517	IMP dehydrogenase activity
FC605_RS14980	COG0123	including yeast histone deacetylase and acetoin utilization protein
FC605_RS14985	COG1360	Flagellar Motor Protein
FC605_RS14990	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FC605_RS14995	COG1609	Transcriptional regulator
FC605_RS15000	COG1605	Chorismate mutase
FC605_RS15000	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FC605_RS15005	COG3118	belongs to the thioredoxin family
FC605_RS15010	COG4980	gas vesicle protein
FC605_RS15015	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
FC605_RS15020	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FC605_RS15025	COG1674	ftsk spoiiie
FC605_RS15030	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FC605_RS15035	COG4848	Belongs to the UPF0354 family
FC605_RS15040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FC605_RS15055	COG1363	Peptidase, m42
FC605_RS15060	COG5584	Small secreted protein
FC605_RS15065	COG0281	malic enzyme
FC605_RS15070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FC605_RS15075	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FC605_RS15085	COG0510	thiamine kinase activity
FC605_RS15090	COG1523	belongs to the glycosyl hydrolase 13 family
FC605_RS15095	COG1597	lipid kinase activity
FC605_RS15105	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FC605_RS15110	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FC605_RS15115	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FC605_RS15120	COG2252	PERMEase
FC605_RS15125	COG4473	ABC transporter
FC605_RS15130	COG1131	(ABC) transporter
FC605_RS15135	COG1349	DNA-binding transcription factor activity
FC605_RS15140	COG1187	pseudouridine synthase activity
FC605_RS15145	COG2244	polysaccharide biosynthetic process
FC605_RS15150	COG2081	HI0933 family
FC605_RS15155	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FC605_RS15165	COG5578	integral membrane protein
FC605_RS15170	COG0673	inositol 2-dehydrogenase activity
FC605_RS15175	COG1653	transport
FC605_RS15180	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FC605_RS15185	COG4209	transmembrane transport
FC605_RS15190	COG2207	Transcriptional regulator
FC605_RS15195	COG1653	transport
FC605_RS15200	COG0395	ABC-type sugar transport system, permease component
FC605_RS15205	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FC605_RS15210	COG2124	cytochrome p450
FC605_RS15215	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FC605_RS15225	COG0156	8-amino-7-oxononanoate synthase activity
FC605_RS15230	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FC605_RS15240	COG1073	alpha beta
FC605_RS15245	COG1609	Transcriptional regulator
FC605_RS15250	COG1653	transport
FC605_RS15255	COG1175	transmembrane transport
FC605_RS15260	COG0395	ABC-type sugar transport system, permease component
FC605_RS15265	COG1486	melibiose metabolic process
FC605_RS15270	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FC605_RS15275	COG0495	leucyl-tRNA aminoacylation
FC605_RS15285	COG1366	Belongs to the anti-sigma-factor antagonist family
FC605_RS15285	COG2202	Pas domain
FC605_RS15290	COG2814	Major facilitator Superfamily
FC605_RS15295	COG2433	Pfam Transposase IS66
FC605_RS15300	COG0577	efflux transmembrane transporter activity
FC605_RS15305	COG1136	(ABC) transporter
FC605_RS15310	COG2205	protein histidine kinase activity
FC605_RS15315	COG0745	RESPONSE REGULATOR receiver
FC605_RS15320	COG0577	efflux transmembrane transporter activity
FC605_RS15325	COG1136	(ABC) transporter
FC605_RS15340	COG1131	(ABC) transporter
FC605_RS15345	COG1725	Transcriptional regulator
FC605_RS15360	COG1242	4 iron, 4 sulfur cluster binding
FC605_RS15365	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FC605_RS15375	COG2267	carboxylic ester hydrolase activity
FC605_RS15380	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FC605_RS15385	COG1113	amino acid transport
FC605_RS15390	COG0367	asparagine synthase
FC605_RS15395	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FC605_RS15400	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FC605_RS15410	COG1506	peptidase
FC605_RS15415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FC605_RS15420	COG1116	anion transmembrane transporter activity
FC605_RS15425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FC605_RS15430	COG0494	nUDIX hydrolase
FC605_RS15435	COG4824	toxin secretion phage lysis holin
FC605_RS15440	COG0783	Belongs to the Dps family
FC605_RS15455	COG1854	S-ribosylhomocysteine lyase activity
FC605_RS15460	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FC605_RS15465	COG0288	reversible hydration of carbon dioxide
FC605_RS15470	COG0254	rRNA binding
FC605_RS15480	COG1294	oxidase, subunit
FC605_RS15490	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FC605_RS15495	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FC605_RS15495	COG1321	iron dependent repressor
FC605_RS15500	COG1121	(ABC) transporter
FC605_RS15505	COG0803	Belongs to the bacterial solute-binding protein 9 family
FC605_RS15510	COG4948	Mandelate Racemase Muconate Lactonizing
FC605_RS15515	COG0318	PFAM AMP-dependent synthetase and ligase
FC605_RS15520	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FC605_RS15525	COG0596	Alpha beta hydrolase
FC605_RS15530	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FC605_RS15535	COG1169	isochorismate synthase
FC605_RS15545	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FC605_RS15550	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FC605_RS15555	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FC605_RS15560	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FC605_RS15565	COG0438	transferase activity, transferring glycosyl groups
FC605_RS15575	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FC605_RS15580	COG0438	transferase activity, transferring glycosyl groups
FC605_RS15585	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FC605_RS15590	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FC605_RS15595	COG0058	SHG alpha-glucan phosphorylase activity
FC605_RS15600	COG0297	glycogen (starch) synthase activity
FC605_RS15605	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FC605_RS15610	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FC605_RS15615	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FC605_RS15740	COG3859	Proton-coupled thiamine transporter YuaJ
FC605_RS15745	COG1247	-acetyltransferase
FC605_RS15750	COG2268	Band 7 protein
FC605_RS15755	COG1585	Membrane protein implicated in regulation of membrane protease activity
FC605_RS15760	COG2318	DinB family
FC605_RS15770	COG1454	alcohol dehydrogenase
FC605_RS15775	COG1012	belongs to the aldehyde dehydrogenase family
FC605_RS15780	COG1510	regulation of RNA biosynthetic process
FC605_RS15790	COG0569	domain protein
FC605_RS15795	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FC605_RS15800	COG4682	membrane
FC605_RS15805	COG1705	Flagellar rod assembly protein muramidase FlgJ
FC605_RS15810	COG0477	Major facilitator Superfamily
FC605_RS15815	COG5553	Cysteine dioxygenase type I
FC605_RS15825	COG1968	undecaprenyl-diphosphatase activity
FC605_RS15830	COG0628	permease
FC605_RS15835	COG0673	inositol 2-dehydrogenase activity
FC605_RS15840	COG4806	L-rhamnose isomerase
FC605_RS15845	COG3254	rhamnose metabolic process
FC605_RS15850	COG1070	Carbohydrate kinase
FC605_RS15855	COG1349	DNA-binding transcription factor activity
FC605_RS15860	COG3347	Dehydrogenase
FC605_RS15860	COG1028	Short-chain dehydrogenase reductase Sdr
FC605_RS15870	COG0840	transmembrane signaling receptor activity
FC605_RS15875	COG0840	transmembrane signaling receptor activity
FC605_RS15880	COG0840	transmembrane signaling receptor activity
FC605_RS15885	COG0840	transmembrane signaling receptor activity
FC605_RS15900	COG0432	Pfam Uncharacterised protein family UPF0047
FC605_RS15910	COG0366	Alpha amylase catalytic
FC605_RS15915	COG1253	flavin adenine dinucleotide binding
FC605_RS15920	COG2738	Putative neutral zinc metallopeptidase
FC605_RS15935	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FC605_RS15950	COG0166	Belongs to the GPI family
FC605_RS15955	COG1979	alcohol dehydrogenase
FC605_RS15960	COG1979	alcohol dehydrogenase
FC605_RS15965	COG2155	Conserved Protein
FC605_RS15970	COG1098	S1 RNA binding domain
FC605_RS15975	COG0436	Aminotransferase
FC605_RS15980	COG1522	sequence-specific DNA binding
FC605_RS15985	COG2267	carboxylic ester hydrolase activity
FC605_RS15995	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FC605_RS16000	COG2205	protein histidine kinase activity
FC605_RS16010	COG5018	Exonuclease
FC605_RS16020	COG2814	Major facilitator Superfamily
FC605_RS16025	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FC605_RS16030	COG3011	Protein conserved in bacteria
FC605_RS16040	COG3290	protein histidine kinase activity
FC605_RS16045	COG4565	transcriptional regulatory protein
FC605_RS16050	COG1744	ABC transporter substrate-binding protein PnrA-like
FC605_RS16055	COG3845	ABC transporter
FC605_RS16060	COG4603	Belongs to the binding-protein-dependent transport system permease family
FC605_RS16065	COG1079	Belongs to the binding-protein-dependent transport system permease family
FC605_RS16070	COG3493	citrate carrier protein
FC605_RS16080	COG2111	Na H antiporter
FC605_RS16080	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FC605_RS16085	COG2111	Na H antiporter
FC605_RS16090	COG1006	Multisubunit Na H antiporter MnhC subunit
FC605_RS16095	COG0651	ATP synthesis coupled electron transport
FC605_RS16100	COG1863	multisubunit Na H antiporter MnhE subunit
FC605_RS16105	COG2212	antiporter activity
FC605_RS16110	COG1320	monovalent cation:proton antiporter activity
FC605_RS16115	COG2050	protein possibly involved in aromatic compounds catabolism
FC605_RS16120	COG2197	response regulator
FC605_RS16125	COG4585	Histidine kinase
FC605_RS16135	COG0142	geranyltranstransferase activity
FC605_RS16155	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FC605_RS16160	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FC605_RS16165	COG1335	isochorismatase
FC605_RS16170	COG5506	Protein of unknown function (DUF1694)
FC605_RS16185	COG0628	permease
FC605_RS16200	COG1418	mRNA catabolic process
FC605_RS16205	COG1028	Short-chain dehydrogenase reductase Sdr
FC605_RS16215	COG1511	domain protein
FC605_RS16220	COG0433	COG0433 Predicted ATPase
FC605_RS16220	COG1674	ftsk spoiiie
FC605_RS16230	COG5417	Belongs to the EsaB family
FC605_RS16235	COG4842	Belongs to the WXG100 family
FC605_RS16245	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FC605_RS16245	COG2508	Transcriptional regulator
FC605_RS16250	COG0686	Belongs to the AlaDH PNT family
FC605_RS16255	COG5634	Uncharacterized conserved protein (DUF2278)
FC605_RS16260	COG3251	PFAM MbtH domain protein
FC605_RS16265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FC605_RS16270	COG3433	isochorismatase activity
FC605_RS16270	COG1535	isochorismatase
FC605_RS16275	COG1021	2,3-dihydroxybenzoate-AMP ligase
FC605_RS16280	COG1169	isochorismate synthase
FC605_RS16285	COG1028	Short-chain dehydrogenase reductase Sdr
FC605_RS16290	COG2819	hydrolase of the alpha beta superfamily
FC605_RS16295	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FC605_RS16300	COG1268	BioY protein
FC605_RS16305	COG2056	Na+-H+ antiporter family
FC605_RS16310	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FC605_RS16315	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FC605_RS16320	COG3584	3D domain protein
FC605_RS16340	COG0492	ferredoxin-NADP+ reductase activity
FC605_RS16350	COG0516	GMP reductase activity
FC605_RS16360	COG2808	Putative FMN-binding domain
FC605_RS16365	COG0456	acetyltransferase
FC605_RS16370	COG0316	Belongs to the HesB IscA family
FC605_RS16375	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FC605_RS16380	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FC605_RS16385	COG4844	belongs to the
FC605_RS16390	COG1252	NADH dehydrogenase
FC605_RS16395	COG4837	Protein of unknown function (DUF1462)
FC605_RS16400	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FC605_RS16405	COG1506	peptidase
FC605_RS16405	COG0823	Involved in the tonB-independent uptake of proteins
FC605_RS16405	COG4946	Tricorn protease homolog
FC605_RS16410	COG0083	homoserine kinase activity
FC605_RS16415	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FC605_RS16420	COG0460	homoserine dehydrogenase
FC605_RS16425	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FC605_RS16430	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FC605_RS16435	COG0647	UMP catabolic process
FC605_RS16440	COG2445	Protein of unknown function DUF86
FC605_RS16445	COG4470	Protein conserved in bacteria
FC605_RS16455	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FC605_RS16460	COG0739	heme binding
FC605_RS16470	COG3377	Domain of unknown function (DUF1805)
FC605_RS16475	COG0737	Belongs to the 5'-nucleotidase family
FC605_RS16480	COG0730	response to heat
FC605_RS16485	COG1801	Protein of unknown function DUF72
FC605_RS16495	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FC605_RS16500	COG2508	Transcriptional regulator
FC605_RS16505	COG2233	PERMEase
FC605_RS16510	COG2233	PERMEase
FC605_RS16515	COG3195	allantoin biosynthetic process
FC605_RS16515	COG3648	Uricase
FC605_RS16520	COG2351	hydroxyisourate hydrolase activity
FC605_RS16530	COG2080	2 iron, 2 sulfur cluster binding
FC605_RS16535	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FC605_RS16540	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FC605_RS16545	COG2068	MobA-Related Protein
FC605_RS16550	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FC605_RS16555	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FC605_RS16560	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FC605_RS16570	COG2356	endonuclease I
FC605_RS16575	COG3842	ATPase activity
FC605_RS16580	COG2188	Transcriptional regulator
FC605_RS16585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FC605_RS16590	COG0395	ABC-type sugar transport system, permease component
FC605_RS16595	COG1175	transmembrane transport
FC605_RS16600	COG1653	transport
FC605_RS16605	COG2222	sugar isomerase
FC605_RS16610	COG0322	excinuclease ABC activity
FC605_RS16615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FC605_RS16630	COG0346	lactoylglutathione lyase activity
FC605_RS16635	COG0640	Transcriptional regulator
FC605_RS16640	COG0719	Fe-S assembly protein
FC605_RS16645	COG0822	iron-sulfur transferase activity
FC605_RS16650	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FC605_RS16655	COG0719	Fe-S assembly protein
FC605_RS16660	COG0396	ATPase activity
FC605_RS16675	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FC605_RS16680	COG1464	Belongs to the NlpA lipoprotein family
FC605_RS16685	COG2011	ABC-type metal ion transport system permease component
FC605_RS16690	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FC605_RS16700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FC605_RS16705	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FC605_RS16715	COG0509	glycine decarboxylation via glycine cleavage system
FC605_RS16720	COG1393	Belongs to the ArsC family
FC605_RS16725	COG1960	acyl-CoA dehydrogenase activity
FC605_RS16730	COG0183	Belongs to the thiolase family
FC605_RS16735	COG1250	3-hydroxyacyl-CoA dehydrogenase
FC605_RS16735	COG1024	Enoyl-CoA hydratase
FC605_RS16745	COG0506	proline dehydrogenase activity
FC605_RS16755	COG5577	PFAM Coat F domain
FC605_RS16760	COG1846	Transcriptional regulator
FC605_RS16765	COG0477	Major facilitator Superfamily
FC605_RS16770	COG1942	4-Oxalocrotonate Tautomerase
FC605_RS16775	COG1028	Short-chain dehydrogenase reductase Sdr
FC605_RS16780	COG0583	DNA-binding transcription factor activity
FC605_RS16790	COG1120	ATPase activity
FC605_RS16805	COG1028	Short-chain dehydrogenase reductase Sdr
FC605_RS16810	COG0783	Belongs to the Dps family
FC605_RS16815	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FC605_RS16820	COG0745	RESPONSE REGULATOR receiver
FC605_RS16825	COG2205	protein histidine kinase activity
FC605_RS16825	COG2770	Histidine kinase
FC605_RS16835	COG1309	transcriptional regulator
FC605_RS16840	COG0114	fumarate hydratase activity
FC605_RS16850	COG0697	spore germination
FC605_RS16855	COG0814	amino acid
FC605_RS16865	COG2197	response regulator
FC605_RS16870	COG4585	Histidine kinase
FC605_RS16875	COG4758	membrane
FC605_RS16880	COG3595	metallopeptidase activity
FC605_RS16885	COG1842	Phage shock protein A
FC605_RS16895	COG2814	Major facilitator Superfamily
FC605_RS16900	COG2096	Adenosyltransferase
FC605_RS16905	COG1120	ATPase activity
FC605_RS16910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FC605_RS16915	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FC605_RS16920	COG1028	Short-chain dehydrogenase reductase Sdr
FC605_RS16925	COG3386	PFAM SMP-30 Gluconolaconase
FC605_RS16930	COG2205	protein histidine kinase activity
FC605_RS16935	COG0745	RESPONSE REGULATOR receiver
FC605_RS16945	COG1191	sigma factor activity
FC605_RS16955	COG2140	Oxalate decarboxylase
FC605_RS16965	COG0577	efflux transmembrane transporter activity
FC605_RS16970	COG1136	(ABC) transporter
FC605_RS16975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FC605_RS16980	COG1120	ATPase activity
FC605_RS16985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FC605_RS16990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FC605_RS16995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FC605_RS17005	COG0531	amino acid
FC605_RS17020	COG1988	membrane-bound metal-dependent
FC605_RS17025	COG1368	sulfuric ester hydrolase activity
FC605_RS17030	COG1910	domain protein
FC605_RS17035	COG0725	ABC transporter, periplasmic molybdate-binding protein
FC605_RS17040	COG4149	molybdate abc transporter
FC605_RS17045	COG0656	L-ascorbic acid biosynthetic process
FC605_RS17055	COG0025	NhaP-type Na H and K H
FC605_RS17060	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FC605_RS17065	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FC605_RS17070	COG3973	AAA domain
FC605_RS17075	COG2860	membrane
FC605_RS17080	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FC605_RS17085	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FC605_RS17090	COG2217	Heavy metal translocating P-type atpase
FC605_RS17095	COG2217	Heavy metal translocating P-type atpase
FC605_RS17100	COG2608	mercury ion transmembrane transporter activity
FC605_RS17105	COG1937	Protein conserved in bacteria
FC605_RS17110	COG0673	inositol 2-dehydrogenase activity
FC605_RS17115	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FC605_RS17120	COG1289	transmembrane transporter activity
FC605_RS17130	COG2076	Multidrug Resistance protein
FC605_RS17135	COG1309	transcriptional regulator
FC605_RS17140	COG1028	Short-chain dehydrogenase reductase Sdr
FC605_RS17150	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FC605_RS17155	COG0557	exoribonuclease II activity
FC605_RS17160	COG1647	Serine aminopeptidase, S33
FC605_RS17165	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FC605_RS17170	COG0596	Alpha beta hydrolase
FC605_RS17175	COG1476	TRANSCRIPTIONal
FC605_RS17180	COG1396	sequence-specific DNA binding
FC605_RS17185	COG1396	sequence-specific DNA binding
FC605_RS17190	COG1733	regulation of RNA biosynthetic process
FC605_RS17195	COG0840	transmembrane signaling receptor activity
FC605_RS17200	COG1174	glycine betaine transport
FC605_RS17205	COG1732	Glycine betaine
FC605_RS17210	COG1174	glycine betaine transport
FC605_RS17215	COG0517	IMP dehydrogenase activity
FC605_RS17215	COG1125	glycine betaine transport
FC605_RS17220	COG1510	regulation of RNA biosynthetic process
FC605_RS17225	COG1174	glycine betaine transport
FC605_RS17230	COG1732	Glycine betaine
FC605_RS17235	COG1174	glycine betaine transport
FC605_RS17240	COG0517	IMP dehydrogenase activity
FC605_RS17240	COG1125	glycine betaine transport
FC605_RS17245	COG1510	regulation of RNA biosynthetic process
FC605_RS17250	COG2095	MarC family integral membrane protein
FC605_RS17260	COG3064	Membrane
FC605_RS17265	COG4640	response to antibiotic
FC605_RS17270	COG0456	acetyltransferase
FC605_RS17275	COG0148	phosphopyruvate hydratase activity
FC605_RS17280	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FC605_RS17285	COG0149	triose-phosphate isomerase activity
FC605_RS17290	COG0126	phosphoglycerate kinase activity
FC605_RS17295	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FC605_RS17300	COG2390	Transcriptional regulator
FC605_RS17305	COG2814	Major facilitator Superfamily
FC605_RS17310	COG1609	Transcriptional regulator
FC605_RS17315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FC605_RS17325	COG0583	DNA-binding transcription factor activity
FC605_RS17330	COG0697	spore germination
FC605_RS17335	COG1113	amino acid transport
FC605_RS17340	COG3858	chitin binding
FC605_RS17345	COG1556	Lactate utilization protein
FC605_RS17350	COG1139	Iron-sulfur cluster binding protein
FC605_RS17355	COG0247	lactate metabolic process
FC605_RS17360	COG2197	response regulator
FC605_RS17365	COG4585	Histidine kinase
FC605_RS17370	COG0842	Transport permease protein
FC605_RS17375	COG1131	(ABC) transporter
FC605_RS17380	COG0596	Alpha beta hydrolase
FC605_RS17385	COG2208	phosphoserine phosphatase activity
FC605_RS17390	COG3867	Arabinogalactan endo-beta-1,4-galactanase
FC605_RS17395	COG1874	Beta-galactosidase
FC605_RS17400	COG3833	ABC-type maltose transport systems, permease component
FC605_RS17405	COG1175	transmembrane transport
FC605_RS17410	COG2182	Extracellular solute-binding protein
FC605_RS17415	COG1609	Transcriptional regulator
FC605_RS17420	COG2186	Transcriptional regulator
FC605_RS17425	COG1620	l-lactate permease
FC605_RS17440	COG5039	Polysaccharide pyruvyl transferase
FC605_RS17445	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FC605_RS17450	COG0110	maltose O-acetyltransferase activity
FC605_RS17455	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FC605_RS17460	COG2244	polysaccharide biosynthetic process
FC605_RS17465	COG1216	Glycosyl transferase, family 2
FC605_RS17470	COG5039	Polysaccharide pyruvyl transferase
FC605_RS17475	COG1216	Glycosyl transferase, family 2
FC605_RS17485	COG0438	transferase activity, transferring glycosyl groups
FC605_RS17490	COG1215	transferase activity, transferring glycosyl groups
FC605_RS17495	COG0438	transferase activity, transferring glycosyl groups
FC605_RS17500	COG1086	Polysaccharide biosynthesis protein
FC605_RS17510	COG3944	biosynthesis protein
FC605_RS17515	COG1396	sequence-specific DNA binding
FC605_RS17520	COG2272	Belongs to the type-B carboxylesterase lipase family
FC605_RS17530	COG3479	Phenolic acid decarboxylase
FC605_RS17540	COG1794	racemase activity, acting on amino acids and derivatives
FC605_RS17545	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FC605_RS17550	COG1621	beta-fructofuranosidase activity
FC605_RS17555	COG1621	beta-fructofuranosidase activity
FC605_RS17560	COG0531	amino acid
FC605_RS17565	COG1309	transcriptional regulator
FC605_RS17570	COG2076	Multidrug Resistance protein
FC605_RS17575	COG2076	Multidrug Resistance protein
FC605_RS17585	COG0277	FAD linked oxidase domain protein
FC605_RS17600	COG0740	serine-type endopeptidase activity
FC605_RS17605	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FC605_RS17610	COG0366	Alpha amylase catalytic
FC605_RS17615	COG1554	hydrolase, family 65, central catalytic
FC605_RS17620	COG5521	maltodextrose utilization protein MalA
FC605_RS17625	COG3833	ABC-type maltose transport systems, permease component
FC605_RS17630	COG1175	transmembrane transport
FC605_RS17635	COG2182	Extracellular solute-binding protein
FC605_RS17640	COG0366	Alpha amylase catalytic
FC605_RS17645	COG1609	Transcriptional regulator
FC605_RS17650	COG1611	Belongs to the LOG family
FC605_RS17655	COG1694	Mazg nucleotide pyrophosphohydrolase
FC605_RS17660	COG0659	secondary active sulfate transmembrane transporter activity
FC605_RS17665	COG0288	reversible hydration of carbon dioxide
FC605_RS17670	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FC605_RS17675	COG0577	efflux transmembrane transporter activity
FC605_RS17680	COG1136	(ABC) transporter
FC605_RS17685	COG5002	protein histidine kinase activity
FC605_RS17690	COG0745	RESPONSE REGULATOR receiver
FC605_RS17700	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FC605_RS17705	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FC605_RS17710	COG1481	regulation of sporulation
FC605_RS17715	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FC605_RS17720	COG1660	Displays ATPase and GTPase activities
FC605_RS17725	COG1051	belongs to the nudix hydrolase family
FC605_RS17730	COG0492	ferredoxin-NADP+ reductase activity
FC605_RS17735	COG3883	PFAM NLP P60 protein
FC605_RS17735	COG0791	NLP P60 protein
FC605_RS17740	COG0457	Tetratricopeptide repeat
FC605_RS17745	COG1132	(ABC) transporter
FC605_RS17780	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FC605_RS17780	COG0140	phosphoribosyl-ATP diphosphatase activity
FC605_RS17785	COG0107	imidazoleglycerol-phosphate synthase activity
FC605_RS17790	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FC605_RS17795	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FC605_RS17800	COG0131	Imidazoleglycerol-phosphate dehydratase
FC605_RS17805	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FC605_RS17810	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FC605_RS17815	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FC605_RS17820	COG4990	cell redox homeostasis
FC605_RS17825	COG5297	Belongs to the glycosyl hydrolase family 6
FC605_RS17830	COG0110	maltose O-acetyltransferase activity
FC605_RS17835	COG0546	phosphoglycolate phosphatase activity
FC605_RS17840	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FC605_RS17845	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FC605_RS17850	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FC605_RS17855	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FC605_RS17860	COG0363	glucosamine-6-phosphate deaminase activity
FC605_RS17865	COG2188	Transcriptional regulator
FC605_RS17870	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FC605_RS17875	COG1846	Transcriptional regulator
FC605_RS17880	COG2124	cytochrome p450
FC605_RS17890	COG1846	Transcriptional regulator
FC605_RS17895	COG2814	Major facilitator Superfamily
FC605_RS17900	COG1950	PFAM Membrane protein of
FC605_RS17905	COG1983	PspC domain protein
FC605_RS17910	COG3595	metallopeptidase activity
FC605_RS17925	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FC605_RS17930	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FC605_RS17935	COG0556	nucleotide-excision repair
FC605_RS17940	COG4897	Protein conserved in bacteria
FC605_RS17945	COG3848	Pyruvate phosphate dikinase
FC605_RS17945	COG0574	Belongs to the PEP-utilizing enzyme family
FC605_RS17950	COG1309	transcriptional regulator
FC605_RS17955	COG2814	Major facilitator Superfamily
FC605_RS17960	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FC605_RS17970	COG3409	Peptidoglycan-binding domain 1 protein
FC605_RS17970	COG0793	Belongs to the peptidase S41A family
FC605_RS17975	COG2177	Part of the ABC transporter FtsEX involved in
FC605_RS17980	COG2884	Cell division ATP-binding protein ftsE
FC605_RS18005	COG0494	nUDIX hydrolase
FC605_RS18010	COG1011	Hydrolase
FC605_RS18040	COG4555	ABC transporter
FC605_RS18050	COG2010	Cytochrome c
FC605_RS18055	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FC605_RS18065	COG0653	protein targeting
FC605_RS18070	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FC605_RS18085	COG1516	flagellar protein fliS
FC605_RS18090	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FC605_RS18095	COG1334	flagellar protein FlaG
FC605_RS18100	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FC605_RS18105	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FC605_RS18110	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
FC605_RS18120	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FC605_RS18125	COG4786	Flagellar basal body rod
FC605_RS18125	COG1256	bacterial-type flagellum assembly
FC605_RS18130	COG3418	PFAM FlgN family protein
FC605_RS18135	COG2747	anti-sigma28 factor FlgM
FC605_RS18145	COG1040	competence protein
FC605_RS18155	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FC605_RS18160	COG1307	EDD domain protein, DegV family
FC605_RS18165	COG2197	response regulator
FC605_RS18170	COG4585	Histidine kinase
FC605_RS18175	COG1739	Uncharacterized protein family UPF0029
FC605_RS18180	COG1316	TRANSCRIPTIONal
FC605_RS18185	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FC605_RS18190	COG0438	transferase activity, transferring glycosyl groups
FC605_RS18195	COG1215	transferase activity, transferring glycosyl groups
FC605_RS18200	COG3206	protein involved in exopolysaccharide biosynthesis
FC605_RS18205	COG3307	-O-antigen
FC605_RS18210	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FC605_RS18215	COG0438	transferase activity, transferring glycosyl groups
FC605_RS18215	COG0297	glycogen (starch) synthase activity
FC605_RS18220	COG2244	polysaccharide biosynthetic process
FC605_RS18230	COG2247	cell wall binding repeat
FC605_RS18230	COG0860	N-Acetylmuramoyl-L-alanine amidase
FC605_RS18235	COG2385	sporulation resulting in formation of a cellular spore
FC605_RS18235	COG2247	cell wall binding repeat
FC605_RS18245	COG1316	TRANSCRIPTIONal
FC605_RS18250	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FC605_RS18255	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FC605_RS18270	COG1215	transferase activity, transferring glycosyl groups
FC605_RS18270	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FC605_RS18275	COG0463	Glycosyl transferase, family 2
FC605_RS18290	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FC605_RS18295	COG1134	teichoic acid transport
FC605_RS18300	COG1682	transport, permease protein
FC605_RS18305	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FC605_RS18310	COG0438	transferase activity, transferring glycosyl groups
FC605_RS18315	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FC605_RS18320	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FC605_RS18325	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FC605_RS18335	COG4193	domain, Protein
FC605_RS18340	COG1482	cell wall glycoprotein biosynthetic process
FC605_RS18345	COG0697	spore germination
FC605_RS18350	COG0814	amino acid
FC605_RS18360	COG2814	Major facilitator Superfamily
FC605_RS18370	COG0561	phosphatase activity
FC605_RS18375	COG0791	NLP P60 protein
FC605_RS18385	COG2843	Capsule synthesis protein
FC605_RS18395	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FC605_RS18405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FC605_RS18410	COG1869	D-ribose catabolic process
FC605_RS18415	COG1129	ABC transporter
FC605_RS18420	COG1172	Belongs to the binding-protein-dependent transport system permease family
FC605_RS18425	COG1879	ABC-type sugar transport system periplasmic component
FC605_RS18430	COG3103	Sh3 type 3 domain protein
FC605_RS18440	COG2249	NAD(P)H dehydrogenase (quinone) activity
FC605_RS18445	COG3527	Alpha-acetolactate decarboxylase
FC605_RS18450	COG0028	Belongs to the TPP enzyme family
FC605_RS18455	COG0583	DNA-binding transcription factor activity
FC605_RS18460	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FC605_RS18475	COG5337	Spore coat protein CotH
FC605_RS18485	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FC605_RS18495	COG0405	Gamma-glutamyltransferase
FC605_RS18500	COG1522	sequence-specific DNA binding
FC605_RS18505	COG2059	Chromate
FC605_RS18510	COG2059	Chromate
FC605_RS18520	COG0655	NAD(P)H dehydrogenase (quinone) activity
FC605_RS18525	COG0583	DNA-binding transcription factor activity
FC605_RS18575	COG5444	nuclease activity
FC605_RS18595	COG3878	Protein conserved in bacteria
FC605_RS18600	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FC605_RS18605	COG4464	protein tyrosine phosphatase activity
FC605_RS18610	COG0489	protein tyrosine kinase activity
FC605_RS18615	COG3944	biosynthesis protein
FC605_RS18625	COG4715	Zinc finger, swim domain protein
FC605_RS18630	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FC605_RS18640	COG0561	phosphatase activity
FC605_RS18645	COG1349	DNA-binding transcription factor activity
FC605_RS18650	COG0629	single-stranded DNA binding
FC605_RS18665	COG3764	Sortase (surface protein transpeptidase)
FC605_RS18670	COG0745	RESPONSE REGULATOR receiver
FC605_RS18670	COG2972	Histidine kinase
FC605_RS18675	COG1970	mechanosensitive ion channel activity
FC605_RS18680	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FC605_RS18685	COG0457	Tetratricopeptide repeat
FC605_RS18690	COG4786	Flagellar basal body rod
FC605_RS18695	COG4786	Flagellar basal body rod
FC605_RS18700	COG1077	Cell shape determining protein MreB Mrl
FC605_RS18705	COG1609	Transcriptional regulator
FC605_RS18715	COG1846	Transcriptional regulator
FC605_RS18720	COG2814	Major facilitator Superfamily
FC605_RS18725	COG3420	alginic acid biosynthetic process
FC605_RS18730	COG1953	Uracil, thiamine, allantoin
FC605_RS18735	COG0477	Major facilitator Superfamily
FC605_RS18740	COG1335	isochorismatase
FC605_RS18750	COG0004	ammonium transporteR
FC605_RS18755	COG0347	Belongs to the P(II) protein family
FC605_RS18760	COG0671	phosphoesterase, PA-phosphatase related
FC605_RS18770	COG0739	heme binding
FC605_RS18775	COG1247	-acetyltransferase
FC605_RS18795	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FC605_RS18800	COG0789	Transcriptional regulator
FC605_RS18810	COG2910	NAD(P)H-binding
FC605_RS18815	COG1959	2 iron, 2 sulfur cluster binding
FC605_RS18820	COG0804	urea catabolic process
FC605_RS18825	COG0832	Belongs to the urease beta subunit family
FC605_RS18830	COG0831	urea catabolic process
FC605_RS18845	COG3237	CsbD-like
FC605_RS18850	COG1994	Peptidase M50
FC605_RS18855	COG0457	Tetratricopeptide repeat
FC605_RS18860	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FC605_RS18865	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FC605_RS18875	COG2304	oxidoreductase activity
FC605_RS18885	COG2304	oxidoreductase activity
FC605_RS18890	COG2385	sporulation resulting in formation of a cellular spore
FC605_RS18895	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FC605_RS18905	COG4836	Membrane
FC605_RS18915	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FC605_RS18920	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FC605_RS18925	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FC605_RS18930	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FC605_RS18935	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FC605_RS18940	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FC605_RS18950	COG0356	it plays a direct role in the translocation of protons across the membrane
FC605_RS18960	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FC605_RS18965	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FC605_RS18970	COG4475	Protein of unknown function (DUF436)
FC605_RS18975	COG0698	ribose 5-phosphate isomerase
FC605_RS18980	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FC605_RS18985	COG1971	Probably functions as a manganese efflux pump
FC605_RS18990	COG0009	L-threonylcarbamoyladenylate synthase
FC605_RS18995	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FC605_RS19015	COG2890	protein-(glutamine-N5) methyltransferase activity
FC605_RS19020	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FC605_RS19025	COG0346	lactoylglutathione lyase activity
FC605_RS19030	COG0789	Transcriptional regulator
FC605_RS19035	COG0679	Auxin Efflux Carrier
FC605_RS19040	COG0281	malic enzyme
FC605_RS19045	COG1435	thymidine kinase activity
FC605_RS19055	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FC605_RS19065	COG1494	fructose-1,6-bisphosphatase
FC605_RS19070	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FC605_RS19075	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FC605_RS19080	COG0191	fructose-bisphosphate aldolase activity
FC605_RS19085	COG2204	response regulator
FC605_RS19090	COG4821	SIS domain
FC605_RS19095	COG0504	CTP synthase activity
FC605_RS19100	COG3343	RNA polymerase activity
FC605_RS19105	COG1960	acyl-CoA dehydrogenase activity
FC605_RS19110	COG0247	lactate metabolic process
FC605_RS19110	COG2181	nitrate reductase activity
FC605_RS19115	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FC605_RS19120	COG4294	response to UV
FC605_RS19135	COG1132	(ABC) transporter
FC605_RS19140	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FC605_RS19150	COG2181	nitrate reductase activity
FC605_RS19155	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FC605_RS19160	COG1140	nitrate reductase beta subunit
FC605_RS19165	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FC605_RS19170	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FC605_RS19180	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FC605_RS19185	COG2223	nitrite transmembrane transporter activity
FC605_RS19190	COG0018	arginyl-trna synthetase
FC605_RS19195	COG4506	Protein conserved in bacteria
FC605_RS19210	COG0535	radical SAM domain protein
FC605_RS19220	COG1131	(ABC) transporter
FC605_RS19225	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FC605_RS19230	COG0612	Peptidase, M16
FC605_RS19235	COG0612	Peptidase, M16
FC605_RS19245	COG3391	amine dehydrogenase activity
FC605_RS19250	COG3391	amine dehydrogenase activity
FC605_RS19260	COG0457	Tetratricopeptide repeat
FC605_RS19275	COG0010	Belongs to the arginase family
FC605_RS19280	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FC605_RS19285	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FC605_RS19300	COG1994	Peptidase M50
FC605_RS19305	COG1942	4-Oxalocrotonate Tautomerase
FC605_RS19310	COG1846	Transcriptional regulator
FC605_RS19315	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FC605_RS19325	COG0477	Major facilitator Superfamily
FC605_RS19330	COG1959	2 iron, 2 sulfur cluster binding
FC605_RS19335	COG3465	dGTPase activity
FC605_RS19340	COG1078	dGTPase activity
FC605_RS19345	COG4844	belongs to the
FC605_RS19355	COG0697	spore germination
FC605_RS19360	COG0095	Lipoate-protein ligase
FC605_RS19365	COG0583	DNA-binding transcription factor activity
FC605_RS19370	COG0280	phosphate acetyltransferase
FC605_RS19375	COG3253	May function as heme-dependent peroxidase
FC605_RS19380	COG1028	Short-chain dehydrogenase reductase Sdr
FC605_RS19385	COG0436	Aminotransferase
FC605_RS19390	COG2814	Major facilitator Superfamily
FC605_RS19395	COG0151	Belongs to the GarS family
FC605_RS19400	COG1028	Short-chain dehydrogenase reductase Sdr
FC605_RS19405	COG1917	Cupin 2, conserved barrel domain protein
FC605_RS19410	COG0077	Prephenate dehydratase
FC605_RS19415	COG2814	Major facilitator Superfamily
FC605_RS19420	COG0833	amino acid
FC605_RS19425	COG4187	Peptidase family M20/M25/M40
FC605_RS19430	COG1012	belongs to the aldehyde dehydrogenase family
FC605_RS19435	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FC605_RS19445	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FC605_RS19450	COG1091	dTDP-4-dehydrorhamnose reductase activity
FC605_RS19455	COG1088	dTDP-glucose 4,6-dehydratase activity
FC605_RS19460	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FC605_RS19465	COG3980	spore coat polysaccharide biosynthesis protein
FC605_RS19470	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
FC605_RS19475	COG2089	acid synthase
FC605_RS19480	COG0456	acetyltransferase
FC605_RS19485	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FC605_RS19490	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FC605_RS19495	COG0463	Glycosyl transferase, family 2
FC605_RS19510	COG2363	Small membrane protein
FC605_RS19515	COG2233	PERMEase
FC605_RS19525	COG1012	belongs to the aldehyde dehydrogenase family
FC605_RS19530	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FC605_RS19535	COG1216	Glycosyl transferase, family 2
FC605_RS19550	COG1695	Transcriptional regulator
FC605_RS19555	COG0351	phosphomethylpyrimidine kinase
FC605_RS19565	COG1621	beta-fructofuranosidase activity
FC605_RS19570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FC605_RS19570	COG1263	PTS System
FC605_RS19575	COG2116	formate transmembrane transporter activity
FC605_RS19580	COG3711	transcriptional antiterminator
FC605_RS19590	COG1404	Belongs to the peptidase S8 family
FC605_RS19595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FC605_RS19600	COG0778	Nitroreductase
FC605_RS19605	COG0772	Belongs to the SEDS family
FC605_RS19620	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FC605_RS19625	COG1845	cytochrome c oxidase, subunit III
FC605_RS19630	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FC605_RS19635	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FC605_RS19640	COG2261	transglycosylase associated protein
FC605_RS19645	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
FC605_RS19650	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FC605_RS19655	COG2246	polysaccharide biosynthetic process
FC605_RS19660	COG1309	transcriptional regulator
FC605_RS19670	COG3162	membrane
FC605_RS19675	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FC605_RS19680	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FC605_RS19685	COG2837	iron assimilation
FC605_RS19695	COG0672	)-iron permease
FC605_RS19700	COG0352	thiamine-phosphate diphosphorylase activity
FC605_RS19705	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FC605_RS19710	COG0583	DNA-binding transcription factor activity
FC605_RS19715	COG1380	Effector of murein hydrolase LrgA
FC605_RS19720	COG1346	cytolysis
FC605_RS19725	COG2814	Major facilitator Superfamily
FC605_RS19730	COG4895	conserved protein (DUF2196)
FC605_RS19735	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FC605_RS19740	COG0346	lactoylglutathione lyase activity
FC605_RS19745	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FC605_RS19750	COG1404	Belongs to the peptidase S8 family
FC605_RS19755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FC605_RS19755	COG1263	PTS System
FC605_RS19760	COG3711	transcriptional antiterminator
FC605_RS19765	COG1442	glycosyl transferase family 8
FC605_RS19770	COG5522	Integral membrane protein (intg_mem_TP0381)
FC605_RS19775	COG1846	Transcriptional regulator
FC605_RS19780	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FC605_RS19785	COG2234	aminopeptidase activity
FC605_RS19800	COG2814	Major facilitator Superfamily
FC605_RS19805	COG2357	RelA SpoT domain protein
FC605_RS19810	COG1575	Belongs to the MenA family. Type 1 subfamily
FC605_RS19830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FC605_RS19835	COG1696	Membrane protein involved in D-alanine export
FC605_RS19840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FC605_RS19845	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FC605_RS19850	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FC605_RS19855	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FC605_RS19860	COG1486	melibiose metabolic process
FC605_RS19865	COG1447	Phosphotransferase system cellobiose-specific component IIA
FC605_RS19870	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FC605_RS19875	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FC605_RS19880	COG3711	transcriptional antiterminator
FC605_RS19880	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FC605_RS19890	COG2094	Belongs to the DNA glycosylase MPG family
FC605_RS19895	COG0753	catalase activity
FC605_RS19900	COG2814	Major facilitator Superfamily
FC605_RS19905	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FC605_RS19910	COG1131	(ABC) transporter
FC605_RS19930	COG1595	DNA-templated transcription, initiation
FC605_RS19935	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FC605_RS19940	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FC605_RS19945	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FC605_RS19950	COG4988	ABC transporter
FC605_RS19955	COG1294	oxidase, subunit
FC605_RS19960	COG1271	oxidase subunit
FC605_RS19965	COG3493	citrate carrier protein
FC605_RS19970	COG0501	Belongs to the peptidase M48B family
FC605_RS19980	COG0726	polysaccharide deacetylase
FC605_RS19985	COG3842	ATPase activity
FC605_RS19990	COG2508	Transcriptional regulator
FC605_RS19995	COG1012	belongs to the aldehyde dehydrogenase family
FC605_RS20000	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FC605_RS20010	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FC605_RS20020	COG4585	Histidine kinase
FC605_RS20025	COG2197	response regulator
FC605_RS20030	COG2195	Cleaves the N-terminal amino acid of tripeptides
FC605_RS20040	COG4894	glucomannan catabolic process
FC605_RS20045	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FC605_RS20050	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FC605_RS20055	COG1028	Short-chain dehydrogenase reductase Sdr
FC605_RS20060	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FC605_RS20065	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FC605_RS20070	COG2610	gluconate transmembrane transporter activity
FC605_RS20075	COG0500	methyltransferase
FC605_RS20080	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FC605_RS20100	COG2851	Citrate transporter
FC605_RS20105	COG2273	Hydrolase Family 16
FC605_RS20110	COG3711	transcriptional antiterminator
FC605_RS20125	COG2270	Major facilitator Superfamily
FC605_RS20130	COG0513	Belongs to the DEAD box helicase family
FC605_RS20135	COG3401	FG-GAP repeat protein
FC605_RS20135	COG2755	lipolytic protein G-D-S-L family
FC605_RS20190	COG0589	response to stress
FC605_RS20195	COG2723	6-phospho-beta-galactosidase activity
FC605_RS20200	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FC605_RS20200	COG1263	PTS System
FC605_RS20200	COG2190	(PTS) system
FC605_RS20205	COG5444	nuclease activity
FC605_RS20215	COG5444	nuclease activity
FC605_RS20230	COG3507	Belongs to the glycosyl hydrolase 43 family
FC605_RS20240	COG2986	histidine ammonia-lyase
FC605_RS20245	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FC605_RS20250	COG1228	amidohydrolase
FC605_RS20255	COG0010	Belongs to the arginase family
FC605_RS20260	COG0833	amino acid
FC605_RS20265	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FC605_RS20270	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FC605_RS20275	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FC605_RS20280	COG2390	Transcriptional regulator
FC605_RS20290	COG3192	ethanolamine utilization protein
FC605_RS20295	COG2079	MmgE PrpD family protein
FC605_RS20300	COG1473	amidohydrolase
FC605_RS20305	COG1126	abc transporter atp-binding protein
FC605_RS20310	COG0765	amino acid transport
FC605_RS20315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FC605_RS20320	COG0456	acetyltransferase
FC605_RS20325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FC605_RS20330	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
FC605_RS20335	COG0561	phosphatase activity
FC605_RS20365	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FC605_RS20370	COG5294	Protein conserved in bacteria
FC605_RS20375	COG0577	efflux transmembrane transporter activity
FC605_RS20380	COG1136	(ABC) transporter
FC605_RS20385	COG2205	protein histidine kinase activity
FC605_RS20390	COG0745	RESPONSE REGULATOR receiver
FC605_RS20395	COG0191	fructose-bisphosphate aldolase activity
FC605_RS20400	COG1082	Xylose isomerase domain protein TIM barrel
FC605_RS20405	COG1082	Xylose isomerase domain protein TIM barrel
FC605_RS20410	COG0673	inositol 2-dehydrogenase activity
FC605_RS20415	COG2814	Major facilitator Superfamily
FC605_RS20420	COG1082	Xylose isomerase domain protein TIM barrel
FC605_RS20425	COG3962	Belongs to the TPP enzyme family
FC605_RS20430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FC605_RS20440	COG1012	belongs to the aldehyde dehydrogenase family
FC605_RS20445	COG1349	DNA-binding transcription factor activity
FC605_RS20450	COG0667	Aldo Keto reductase
FC605_RS20465	COG2814	Major facilitator Superfamily
FC605_RS20470	COG0326	Molecular chaperone. Has ATPase activity
FC605_RS20480	COG1028	Short-chain dehydrogenase reductase Sdr
FC605_RS20485	COG1309	transcriptional regulator
FC605_RS20490	COG1012	belongs to the aldehyde dehydrogenase family
FC605_RS20500	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FC605_RS20510	COG1714	RDD family
FC605_RS20515	COG2311	Membrane
FC605_RS20520	COG1917	Cupin 2, conserved barrel domain protein
FC605_RS20525	COG1309	transcriptional regulator
FC605_RS20530	COG1028	Short-chain dehydrogenase reductase Sdr
FC605_RS20535	COG1846	Transcriptional regulator
FC605_RS20540	COG1380	Effector of murein hydrolase LrgA
FC605_RS20545	COG1346	cytolysis
FC605_RS20550	COG5039	Polysaccharide pyruvyl transferase
FC605_RS20555	COG1929	Belongs to the glycerate kinase type-1 family
FC605_RS20560	COG1802	Transcriptional regulator
FC605_RS20565	COG1070	Carbohydrate kinase
FC605_RS20570	COG2610	gluconate transmembrane transporter activity
FC605_RS20575	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FC605_RS20580	COG0450	alkyl hydroperoxide reductase
FC605_RS20585	COG3634	alkyl hydroperoxide reductase activity
FC605_RS20590	COG2723	6-phospho-beta-galactosidase activity
FC605_RS20595	COG2190	(PTS) system
FC605_RS20600	COG2190	(PTS) system
FC605_RS20600	COG1263	PTS System
FC605_RS20600	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FC605_RS20605	COG2188	Transcriptional regulator
FC605_RS20615	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
FC605_RS20620	COG0210	DNA helicase
FC605_RS20640	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FC605_RS20655	COG1063	alcohol dehydrogenase
FC605_RS20675	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
FC605_RS20680	COG0456	acetyltransferase
FC605_RS20685	COG0457	Tetratricopeptide repeat
FC605_RS20695	COG0010	Belongs to the arginase family
FC605_RS20705	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FC605_RS20710	COG3829	transcription factor binding
FC605_RS20715	COG5002	protein histidine kinase activity
FC605_RS20720	COG0745	RESPONSE REGULATOR receiver
FC605_RS20740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FC605_RS20745	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FC605_RS20750	COG4853	Protein conserved in bacteria
FC605_RS20755	COG4863	YycH protein
FC605_RS20760	COG5002	protein histidine kinase activity
FC605_RS20765	COG0745	RESPONSE REGULATOR receiver
FC605_RS20795	COG0346	lactoylglutathione lyase activity
FC605_RS20800	COG0305	Participates in initiation and elongation during chromosome replication
FC605_RS20815	COG3093	addiction module antidote protein HigA
FC605_RS20820	COG2807	transmembrane transport
FC605_RS20825	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FC605_RS20830	COG0359	binds to the 23S rRNA
FC605_RS20835	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
FC605_RS20840	COG4241	membrane
FC605_RS20850	COG5577	PFAM Coat F domain
FC605_RS20855	COG1733	regulation of RNA biosynthetic process
FC605_RS20860	COG1227	inorganic diphosphatase activity
FC605_RS20870	COG2271	Major facilitator Superfamily
FC605_RS20875	COG4978	Transcriptional regulator
FC605_RS20875	COG0789	Transcriptional regulator
FC605_RS20885	COG4319	ketosteroid isomerase
FC605_RS20890	COG1357	PFAM Pentapeptide repeats (8 copies)
FC605_RS20895	COG2814	Major facilitator Superfamily
FC605_RS20900	COG0583	DNA-binding transcription factor activity
FC605_RS20905	COG2153	protein acetylation
FC605_RS20920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FC605_RS20925	COG1846	Transcriptional regulator
FC605_RS20930	COG2153	protein acetylation
FC605_RS20935	COG2364	Membrane
FC605_RS20940	COG0456	acetyltransferase
FC605_RS20945	COG2315	Protein conserved in bacteria
FC605_RS20950	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FC605_RS20960	COG2814	Major facilitator Superfamily
FC605_RS20970	COG1331	Highly conserved protein containing a thioredoxin domain
FC605_RS20975	COG0789	Transcriptional regulator
FC605_RS20980	COG0697	spore germination
FC605_RS20985	COG1331	Highly conserved protein containing a thioredoxin domain
FC605_RS20990	COG1266	CAAX protease self-immunity
FC605_RS20995	COG2814	Major facilitator Superfamily
FC605_RS20995	COG0477	Major facilitator Superfamily
FC605_RS21000	COG0110	maltose O-acetyltransferase activity
FC605_RS21005	COG0346	lactoylglutathione lyase activity
FC605_RS21010	COG1609	Transcriptional regulator
FC605_RS21015	COG0708	Exodeoxyribonuclease III
FC605_RS21020	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FC605_RS21025	COG0629	single-stranded DNA binding
FC605_RS21030	COG0360	Binds together with S18 to 16S ribosomal RNA
FC605_RS21035	COG0012	GTP binding
FC605_RS21040	COG0243	molybdopterin cofactor binding
FC605_RS21045	COG4481	Protein conserved in bacteria
FC605_RS21050	COG3949	Membrane
FC605_RS21060	COG1475	DNA binding
FC605_RS21065	COG1192	Involved in chromosome partitioning
FC605_RS21075	COG1475	DNA binding
FC605_RS21080	COG0357	Ribosomal RNA small subunit methyltransferase G
FC605_RS21085	COG0445	tRNA wobble uridine modification
FC605_RS21090	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FC605_RS21095	COG1847	R3H domain protein
FC605_RS21100	COG0706	membrane insertase activity
FC605_RS21105	COG0594	ribonuclease P activity