locus-tag	class	description
OB04_RS00005	COG1686	Belongs to the peptidase S11 family
OB04_RS00010	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
OB04_RS00015	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
OB04_RS00025	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OB04_RS00035	COG1428	Deoxynucleoside kinase
OB04_RS00040	COG1428	Deoxynucleoside kinase
OB04_RS00045	COG1388	LysM domain
OB04_RS00045	COG3858	chitin binding
OB04_RS00050	COG1335	isochorismatase
OB04_RS00055	COG0590	tRNA wobble adenosine to inosine editing
OB04_RS00060	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OB04_RS00065	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OB04_RS00070	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OB04_RS00115	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
OB04_RS00120	COG3853	Toxic anion resistance protein (TelA)
OB04_RS00125	COG1982	Orn Lys Arg decarboxylase major
OB04_RS00130	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OB04_RS00135	COG3870	Protein conserved in bacteria
OB04_RS00140	COG1728	Protein conserved in bacteria
OB04_RS00145	COG0470	DNA polymerase III
OB04_RS00150	COG1774	PSP1 C-terminal conserved region
OB04_RS00155	COG4467	Involved in initiation control of chromosome replication
OB04_RS00160	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
OB04_RS00165	COG2827	Endonuclease containing a URI domain
OB04_RS00170	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OB04_RS00175	COG2002	toxin-antitoxin pair type II binding
OB04_RS00180	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OB04_RS00180	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OB04_RS00185	COG0084	hydrolase, TatD family'
OB04_RS00190	COG3584	3D domain protein
OB04_RS00190	COG3583	domain protein
OB04_RS00195	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
OB04_RS00200	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OB04_RS00210	COG4466	Protein conserved in bacteria
OB04_RS00220	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OB04_RS00225	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OB04_RS00230	COG0251	oxidation-reduction process
OB04_RS00235	COG2088	sporulation resulting in formation of a cellular spore
OB04_RS00245	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OB04_RS00250	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OB04_RS00255	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OB04_RS00260	COG0193	aminoacyl-tRNA hydrolase activity
OB04_RS00270	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OB04_RS00275	COG2002	toxin-antitoxin pair type II binding
OB04_RS00280	COG2244	polysaccharide biosynthetic process
OB04_RS00285	COG3956	TIGRFAM MazG family protein
OB04_RS00290	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
OB04_RS00305	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
OB04_RS00310	COG1098	S1 RNA binding domain
OB04_RS00325	COG2208	phosphoserine phosphatase activity
OB04_RS00330	COG2304	oxidoreductase activity
OB04_RS00335	COG0515	serine threonine protein kinase
OB04_RS00340	COG0037	tRNA processing
OB04_RS00345	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
OB04_RS00350	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OB04_RS00355	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
OB04_RS00360	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
OB04_RS00365	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OB04_RS00370	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OB04_RS00375	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OB04_RS00380	COG0512	Glutamine amidotransferase of anthranilate synthase
OB04_RS00385	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OB04_RS00390	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OB04_RS00395	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OB04_RS00400	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OB04_RS00405	COG1396	sequence-specific DNA binding
OB04_RS00410	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OB04_RS00415	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
OB04_RS00450	COG4463	regulation of RNA biosynthetic process
OB04_RS00455	COG3880	PFAM UvrB UvrC protein
OB04_RS00460	COG3869	Catalyzes the specific phosphorylation of arginine residues in
OB04_RS00465	COG0542	response to heat
OB04_RS00470	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
OB04_RS00475	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
OB04_RS00480	COG4956	integral membrane protein (PIN domain superfamily)
OB04_RS00485	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
OB04_RS00490	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
OB04_RS00495	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OB04_RS00505	COG1045	serine acetyltransferase
OB04_RS00510	COG0215	cysteine-tRNA ligase activity
OB04_RS00515	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
OB04_RS00520	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OB04_RS00525	COG3688	RNA-binding protein containing a PIN domain
OB04_RS00530	COG1595	DNA-templated transcription, initiation
OB04_RS00540	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
OB04_RS00545	COG0250	Participates in transcription elongation, termination and antitermination
OB04_RS00555	COG0081	regulation of translation
OB04_RS00560	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OB04_RS00570	COG2813	Specifically methylates the guanine in position
OB04_RS00575	COG0085	RNA polymerase activity
OB04_RS00580	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OB04_RS00585	COG1358	cellular component organization or biogenesis
OB04_RS00590	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OB04_RS00595	COG0049	tRNA binding
OB04_RS00600	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OB04_RS00605	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OB04_RS00610	COG0596	Alpha beta hydrolase
OB04_RS00620	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OB04_RS00625	COG0088	Forms part of the polypeptide exit tunnel
OB04_RS00635	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OB04_RS00655	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OB04_RS00665	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OB04_RS00670	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OB04_RS00680	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OB04_RS00690	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OB04_RS00695	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OB04_RS00700	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OB04_RS00705	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
OB04_RS00715	COG0200	Binds to the 23S rRNA
OB04_RS00720	COG0201	protein transport
OB04_RS00725	COG0563	adenylate kinase activity
OB04_RS00730	COG0024	Methionine aminopeptidase
OB04_RS00735	COG2163	COG2163 Ribosomal protein L14E L6E L27E
OB04_RS00745	COG0257	Belongs to the bacterial ribosomal protein bL36 family
OB04_RS00750	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OB04_RS00755	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OB04_RS00760	COG0202	RNA polymerase activity
OB04_RS00765	COG0203	ribosomal protein L17
OB04_RS00770	COG1122	ATPase activity
OB04_RS00775	COG1122	ATPase activity
OB04_RS00780	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OB04_RS00785	COG0101	tRNA pseudouridine synthase activity
OB04_RS00790	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OB04_RS00795	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OB04_RS00800	COG2226	methyltransferase
OB04_RS00810	COG0860	N-Acetylmuramoyl-L-alanine amidase
OB04_RS00815	COG0489	protein tyrosine kinase activity
OB04_RS00825	COG2194	sulfuric ester hydrolase activity
OB04_RS00830	COG0726	polysaccharide deacetylase
OB04_RS00865	COG0659	secondary active sulfate transmembrane transporter activity
OB04_RS00870	COG0385	Bile acid
OB04_RS00875	COG2819	hydrolase of the alpha beta superfamily
OB04_RS00880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OB04_RS00885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OB04_RS00890	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OB04_RS00895	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OB04_RS00895	COG2207	Transcriptional regulator
OB04_RS00900	COG3876	Protein conserved in bacteria
OB04_RS00905	COG1472	Belongs to the glycosyl hydrolase 3 family
OB04_RS00910	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OB04_RS00915	COG1263	PTS System
OB04_RS00915	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OB04_RS00920	COG1737	Transcriptional regulator
OB04_RS00925	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
OB04_RS00930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OB04_RS00935	COG1683	Conserved Protein
OB04_RS00965	COG1595	DNA-templated transcription, initiation
OB04_RS00970	COG5662	AntiSigma factor
OB04_RS00975	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OB04_RS00980	COG4856	YbbR-like protein
OB04_RS00985	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OB04_RS00990	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OB04_RS00995	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
OB04_RS01000	COG2169	Transcriptional regulator
OB04_RS01005	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OB04_RS01010	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OB04_RS01015	COG3002	Belongs to the UPF0753 family
OB04_RS01020	COG0288	reversible hydration of carbon dioxide
OB04_RS01030	COG5609	conserved protein (DUF2294)
OB04_RS01040	COG0640	Transcriptional regulator
OB04_RS01045	COG2814	Major facilitator Superfamily
OB04_RS01055	COG0596	Alpha beta hydrolase
OB04_RS01060	COG0745	RESPONSE REGULATOR receiver
OB04_RS01065	COG0642	Histidine kinase
OB04_RS01075	COG0515	serine threonine protein kinase
OB04_RS01090	COG1113	amino acid transport
OB04_RS01105	COG2602	Beta-lactamase
OB04_RS01110	COG2124	cytochrome p450
OB04_RS01120	COG0531	amino acid
OB04_RS01125	COG0584	glycerophosphoryl diester phosphodiesterase
OB04_RS01130	COG2271	Major facilitator Superfamily
OB04_RS01140	COG0456	acetyltransferase
OB04_RS01140	COG1846	Transcriptional regulator
OB04_RS01145	COG2271	Major facilitator Superfamily
OB04_RS01155	COG3409	Peptidoglycan-binding domain 1 protein
OB04_RS01160	COG0697	spore germination
OB04_RS01165	COG2207	Transcriptional regulator
OB04_RS01165	COG1917	Cupin 2, conserved barrel domain protein
OB04_RS01170	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
OB04_RS01175	COG3591	Belongs to the peptidase S1B family
OB04_RS01185	COG0596	Alpha beta hydrolase
OB04_RS01190	COG1183	phosphatidylcholine synthase activity
OB04_RS01195	COG0586	Pfam SNARE associated Golgi protein
OB04_RS01200	COG0688	phosphatidylethanolamine metabolic process
OB04_RS01215	COG2207	Transcriptional regulator
OB04_RS01220	COG1054	Belongs to the UPF0176 family
OB04_RS01225	COG1301	dicarboxylic acid transport
OB04_RS01230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OB04_RS01230	COG1263	PTS System
OB04_RS01230	COG2190	(PTS) system
OB04_RS01235	COG0363	glucosamine-6-phosphate deaminase activity
OB04_RS01240	COG2188	Transcriptional regulator
OB04_RS01250	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OB04_RS01255	COG0833	amino acid
OB04_RS01260	COG2040	homocysteine
OB04_RS01270	COG1115	amino acid carrier protein
OB04_RS01275	COG2066	Belongs to the glutaminase family
OB04_RS01280	COG4191	Histidine kinase
OB04_RS01285	COG0784	Response regulator, receiver
OB04_RS01290	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OB04_RS01295	COG1012	belongs to the aldehyde dehydrogenase family
OB04_RS01300	COG2271	Major facilitator Superfamily
OB04_RS01305	COG4948	Mandelate Racemase Muconate Lactonizing
OB04_RS01310	COG2186	Transcriptional regulator
OB04_RS01315	COG2721	sulfolactate sulfo-lyase activity
OB04_RS01320	COG3173	Aminoglycoside phosphotransferase
OB04_RS01330	COG0697	spore germination
OB04_RS01335	COG0745	RESPONSE REGULATOR receiver
OB04_RS01340	COG2205	protein histidine kinase activity
OB04_RS01345	COG1131	(ABC) transporter
OB04_RS01365	COG3773	Cell wall hydrolase
OB04_RS01370	COG2304	oxidoreductase activity
OB04_RS01380	COG3540	Alkaline phosphatase
OB04_RS01385	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OB04_RS01390	COG0805	protein transport
OB04_RS01395	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
OB04_RS01400	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OB04_RS01405	COG0477	Major facilitator Superfamily
OB04_RS01410	COG1309	transcriptional regulator
OB04_RS01415	COG0252	asparaginase activity
OB04_RS01420	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
OB04_RS01425	COG1714	RDD family
OB04_RS01430	COG1405	negative regulation of cell septum assembly
OB04_RS01430	COG3012	SEC-C Motif Domain Protein
OB04_RS01435	COG3290	protein histidine kinase activity
OB04_RS01440	COG3279	Response regulator of the LytR AlgR family
OB04_RS01445	COG4555	ABC transporter
OB04_RS01450	COG1668	transmembrane transport
OB04_RS01455	COG0667	Aldo Keto reductase
OB04_RS01465	COG1595	DNA-templated transcription, initiation
OB04_RS01470	COG1595	DNA-templated transcription, initiation
OB04_RS01475	COG1876	peptidase activity
OB04_RS01480	COG0457	Tetratricopeptide repeat
OB04_RS01485	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_RS01490	COG0366	Alpha amylase catalytic
OB04_RS01495	COG0803	Belongs to the bacterial solute-binding protein 9 family
OB04_RS01500	COG1121	(ABC) transporter
OB04_RS01505	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OB04_RS01510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OB04_RS01515	COG2310	stress, protein
OB04_RS01520	COG2310	stress, protein
OB04_RS01525	COG2310	stress, protein
OB04_RS01530	COG0861	Integral membrane protein TerC family
OB04_RS01540	COG3853	Toxic anion resistance protein (TelA)
OB04_RS01545	COG0477	Major facilitator Superfamily
OB04_RS01550	COG2814	Major facilitator Superfamily
OB04_RS01555	COG0640	Transcriptional regulator
OB04_RS01560	COG0517	IMP dehydrogenase activity
OB04_RS01560	COG4175	Glycine betaine
OB04_RS01565	COG4176	ABC-type proline glycine betaine transport system permease component
OB04_RS01570	COG2113	Glycine betaine
OB04_RS01575	COG1473	amidohydrolase
OB04_RS01580	COG1288	antiporter activity
OB04_RS01595	COG0366	Alpha amylase catalytic
OB04_RS01600	COG0039	L-malate dehydrogenase activity
OB04_RS01605	COG1620	l-lactate permease
OB04_RS01610	COG2814	Major facilitator Superfamily
OB04_RS01615	COG1846	Transcriptional regulator
OB04_RS01620	COG1280	lysine exporter protein (LysE YggA)
OB04_RS01625	COG3403	YqcI/YcgG family
OB04_RS01630	COG1113	amino acid transport
OB04_RS01635	COG3665	Urea carboxylase-associated protein
OB04_RS01640	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OB04_RS01645	COG1660	Displays ATPase and GTPase activities
OB04_RS01650	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OB04_RS01655	COG2226	methyltransferase
OB04_RS01660	COG0583	DNA-binding transcription factor activity
OB04_RS01665	COG3458	cephalosporin-C deacetylase activity
OB04_RS01670	COG3541	Predicted nucleotidyltransferase
OB04_RS01675	COG0506	proline dehydrogenase activity
OB04_RS01680	COG1012	belongs to the aldehyde dehydrogenase family
OB04_RS01685	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OB04_RS01690	COG2508	Transcriptional regulator
OB04_RS01695	COG3689	TIGRFAM TIGR03943 family protein
OB04_RS01700	COG0701	Predicted permease
OB04_RS01705	COG2267	carboxylic ester hydrolase activity
OB04_RS01710	COG0492	ferredoxin-NADP+ reductase activity
OB04_RS01715	COG1587	Uroporphyrinogen-III synthase
OB04_RS01715	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OB04_RS01720	COG2146	nitrite reductase [NAD(P)H] activity
OB04_RS01725	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OB04_RS01730	COG0243	molybdopterin cofactor binding
OB04_RS01735	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OB04_RS01740	COG2223	nitrite transmembrane transporter activity
OB04_RS01745	COG1469	GTP cyclohydrolase I activity
OB04_RS01750	COG1376	ErfK ybiS ycfS ynhG family protein
OB04_RS01760	COG0523	cobalamin synthesis protein
OB04_RS01765	COG0765	amino acid transport
OB04_RS01770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OB04_RS01780	COG1714	RDD family
OB04_RS01790	COG2723	6-phospho-beta-galactosidase activity
OB04_RS01800	COG3209	COG3209 Rhs family protein
OB04_RS01805	COG0840	transmembrane signaling receptor activity
OB04_RS01805	COG3290	protein histidine kinase activity
OB04_RS01810	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
OB04_RS01815	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
OB04_RS01820	COG1733	regulation of RNA biosynthetic process
OB04_RS01830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OB04_RS01835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OB04_RS01840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OB04_RS01845	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
OB04_RS01850	COG2814	Major facilitator Superfamily
OB04_RS01860	COG0697	spore germination
OB04_RS01865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OB04_RS01875	COG2364	Membrane
OB04_RS01880	COG1126	abc transporter atp-binding protein
OB04_RS01885	COG0765	amino acid transport
OB04_RS01890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OB04_RS01895	COG0583	DNA-binding transcription factor activity
OB04_RS01900	COG0163	prenyltransferase activity
OB04_RS01905	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
OB04_RS01920	COG0596	Alpha beta hydrolase
OB04_RS01925	COG3104	oligopeptide transport
OB04_RS01930	COG5434	Belongs to the glycosyl hydrolase 28 family
OB04_RS01940	COG0697	spore germination
OB04_RS01950	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OB04_RS01955	COG1136	(ABC) transporter
OB04_RS01960	COG0577	efflux transmembrane transporter activity
OB04_RS01965	COG0745	RESPONSE REGULATOR receiver
OB04_RS01970	COG5002	protein histidine kinase activity
OB04_RS01970	COG3850	Histidine kinase
OB04_RS01975	COG0457	Tetratricopeptide repeat
OB04_RS01995	COG0527	aspartate kinase activity
OB04_RS02000	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OB04_RS02005	COG4605	iron ion homeostasis
OB04_RS02010	COG4604	ABC transporter, ATP-binding protein
OB04_RS02015	COG4607	ABC-type enterochelin transport system periplasmic component
OB04_RS02020	COG2814	Major facilitator Superfamily
OB04_RS02025	COG1309	transcriptional regulator
OB04_RS02030	COG0778	Nitroreductase
OB04_RS02035	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
OB04_RS02040	COG0640	Transcriptional regulator
OB04_RS02045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OB04_RS02050	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OB04_RS02055	COG1012	belongs to the aldehyde dehydrogenase family
OB04_RS02060	COG4975	Glucose uptake
OB04_RS02065	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_RS02070	COG4549	nuclear export factor GLE1
OB04_RS02075	COG2372	response to copper ion
OB04_RS02075	COG1276	copper resistance
OB04_RS02080	COG1349	DNA-binding transcription factor activity
OB04_RS02090	COG2213	PTS system mannitol-specific
OB04_RS02095	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OB04_RS02100	COG0246	Mannitol dehydrogenase
OB04_RS02105	COG0473	3-isopropylmalate dehydrogenase activity
OB04_RS02110	COG0681	Belongs to the peptidase S26 family
OB04_RS02120	COG0412	Dienelactone hydrolase
OB04_RS02125	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OB04_RS02135	COG0561	phosphatase activity
OB04_RS02140	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
OB04_RS02145	COG1914	H( )-stimulated, divalent metal cation uptake system
OB04_RS02150	COG4336	lyase activity
OB04_RS02155	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
OB04_RS02160	COG1984	allophanate hydrolase subunit 2
OB04_RS02165	COG1414	Transcriptional regulator
OB04_RS02170	COG2755	lipolytic protein G-D-S-L family
OB04_RS02180	COG2329	Antibiotic biosynthesis monooxygenase
OB04_RS02185	COG0768	penicillin binding
OB04_RS02190	COG4989	oxidoreductase activity
OB04_RS02195	COG3711	transcriptional antiterminator
OB04_RS02200	COG0318	PFAM AMP-dependent synthetase and ligase
OB04_RS02205	COG2226	methyltransferase
OB04_RS02210	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_RS02215	COG1917	Cupin 2, conserved barrel domain protein
OB04_RS02220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OB04_RS02225	COG3871	stress protein (general stress protein 26)
OB04_RS02235	COG2814	Major facilitator Superfamily
OB04_RS02240	COG1522	sequence-specific DNA binding
OB04_RS02245	COG0551	DNA topoisomerase type I activity
OB04_RS02245	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OB04_RS02250	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
OB04_RS02255	COG3706	GGDEF domain
OB04_RS02260	COG5298	Protein conserved in bacteria
OB04_RS02265	COG1215	transferase activity, transferring glycosyl groups
OB04_RS02275	COG0531	amino acid
OB04_RS02280	COG0494	nUDIX hydrolase
OB04_RS02285	COG0028	Belongs to the TPP enzyme family
OB04_RS02300	COG1914	H( )-stimulated, divalent metal cation uptake system
OB04_RS02305	COG2261	transglycosylase associated protein
OB04_RS02310	COG4876	unkown
OB04_RS02315	COG2217	Heavy metal translocating P-type atpase
OB04_RS02320	COG3729	General stress protein
OB04_RS02325	COG0662	Cupin 2, conserved barrel domain protein
OB04_RS02330	COG2329	Antibiotic biosynthesis monooxygenase
OB04_RS02335	COG3546	catalase activity
OB04_RS02340	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OB04_RS02345	COG3290	protein histidine kinase activity
OB04_RS02350	COG4565	transcriptional regulatory protein
OB04_RS02355	COG1301	dicarboxylic acid transport
OB04_RS02360	COG0628	permease
OB04_RS02370	COG1131	(ABC) transporter
OB04_RS02375	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
OB04_RS02385	COG1960	acyl-CoA dehydrogenase activity
OB04_RS02400	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OB04_RS02405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OB04_RS02410	COG1181	Belongs to the D-alanine--D-alanine ligase family
OB04_RS02415	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OB04_RS02420	COG0513	Belongs to the DEAD box helicase family
OB04_RS02425	COG3402	PFAM membrane-flanked domain
OB04_RS02430	COG3428	Bacterial PH domain
OB04_RS02435	COG0705	Rhomboid family
OB04_RS02440	COG0736	holo-[acyl-carrier-protein] synthase activity
OB04_RS02445	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
OB04_RS02450	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OB04_RS02455	COG0864	Transcriptional regulator
OB04_RS02460	COG2337	Toxic component of a toxin-antitoxin (TA) module
OB04_RS02465	COG1366	Belongs to the anti-sigma-factor antagonist family
OB04_RS02470	COG1366	Belongs to the anti-sigma-factor antagonist family
OB04_RS02475	COG2172	sigma factor antagonist activity
OB04_RS02480	COG2208	phosphoserine phosphatase activity
OB04_RS02485	COG1366	Belongs to the anti-sigma-factor antagonist family
OB04_RS02490	COG2172	sigma factor antagonist activity
OB04_RS02495	COG1191	sigma factor activity
OB04_RS02500	COG2208	phosphoserine phosphatase activity
OB04_RS02505	COG1846	Transcriptional regulator
OB04_RS02510	COG2183	response to ionizing radiation
OB04_RS02520	COG3091	SprT-like family
OB04_RS02575	COG5444	nuclease activity
OB04_RS02580	COG1476	TRANSCRIPTIONal
OB04_RS02590	COG3239	Fatty acid desaturase
OB04_RS02600	COG1278	Cold shock
OB04_RS02605	COG1329	Transcriptional regulator
OB04_RS02610	COG0697	spore germination
OB04_RS02615	COG2207	Transcriptional regulator
OB04_RS02615	COG1917	Cupin 2, conserved barrel domain protein
OB04_RS02620	COG0697	spore germination
OB04_RS02630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OB04_RS02635	COG0477	Major facilitator Superfamily
OB04_RS02645	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
OB04_RS02675	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OB04_RS02680	COG1309	transcriptional regulator
OB04_RS02685	COG0697	spore germination
OB04_RS02690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OB04_RS02695	COG2030	dehydratase
OB04_RS02700	COG3545	Serine hydrolase
OB04_RS02705	COG1733	regulation of RNA biosynthetic process
OB04_RS02710	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OB04_RS02715	COG1733	regulation of RNA biosynthetic process
OB04_RS02725	COG2814	Major facilitator Superfamily
OB04_RS02730	COG1309	transcriptional regulator
OB04_RS02740	COG0640	Transcriptional regulator
OB04_RS02745	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OB04_RS02755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OB04_RS02760	COG0697	spore germination
OB04_RS02765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OB04_RS02770	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OB04_RS02775	COG0640	Transcriptional regulator
OB04_RS02780	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OB04_RS02795	COG4585	Histidine kinase
OB04_RS02800	COG2197	response regulator
OB04_RS02805	COG2409	Drug exporters of the RND superfamily
OB04_RS02810	COG0596	Alpha beta hydrolase
OB04_RS02815	COG1811	Na channel or pump
OB04_RS02820	COG4978	Transcriptional regulator
OB04_RS02820	COG0789	Transcriptional regulator
OB04_RS02825	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OB04_RS02830	COG0778	Nitroreductase
OB04_RS02835	COG0346	lactoylglutathione lyase activity
OB04_RS02840	COG2259	Doxx family
OB04_RS02845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OB04_RS02865	COG2323	membrane
OB04_RS02875	COG0071	Belongs to the small heat shock protein (HSP20) family
OB04_RS02890	COG1309	transcriptional regulator
OB04_RS02900	COG0456	acetyltransferase
OB04_RS02905	COG0488	(ABC) transporter
OB04_RS02910	COG1113	amino acid transport
OB04_RS02915	COG2318	DinB family
OB04_RS02920	COG1846	Transcriptional regulator
OB04_RS02925	COG1033	growth of symbiont in host cell
OB04_RS02925	COG2409	Drug exporters of the RND superfamily
OB04_RS02930	COG0778	Nitroreductase
OB04_RS02935	COG1846	Transcriptional regulator
OB04_RS02940	COG2814	Major facilitator Superfamily
OB04_RS02945	COG0730	response to heat
OB04_RS02950	COG1802	Transcriptional regulator
OB04_RS02955	COG1388	LysM domain
OB04_RS02955	COG3858	chitin binding
OB04_RS02960	COG1819	glycosyl
OB04_RS02970	COG1785	Belongs to the alkaline phosphatase family
OB04_RS02975	COG5646	InterPro IPR014922
OB04_RS02985	COG0454	-acetyltransferase
OB04_RS02990	COG1078	dGTPase activity
OB04_RS02995	COG1388	LysM domain
OB04_RS03000	COG2814	Major facilitator Superfamily
OB04_RS03005	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OB04_RS03010	COG1447	Phosphotransferase system cellobiose-specific component IIA
OB04_RS03015	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OB04_RS03020	COG2723	6-phospho-beta-galactosidase activity
OB04_RS03025	COG2188	Transcriptional regulator
OB04_RS03030	COG1940	carbohydrate kinase activity
OB04_RS03035	COG1482	cell wall glycoprotein biosynthetic process
OB04_RS03040	COG4124	Belongs to the glycosyl hydrolase 26 family
OB04_RS03095	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OB04_RS03100	COG0802	atpase or kinase
OB04_RS03105	COG1214	PFAM Peptidase M22, glycoprotease
OB04_RS03110	COG0456	acetyltransferase
OB04_RS03115	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OB04_RS03120	COG0488	(ABC) transporter
OB04_RS03125	COG0315	cyclic pyranopterin monophosphate synthase activity
OB04_RS03130	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
OB04_RS03135	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OB04_RS03140	COG0805	protein transport
OB04_RS03150	COG1266	CAAX protease self-immunity
OB04_RS03160	COG0459	protein refolding
OB04_RS03165	COG4974	Belongs to the 'phage' integrase family
OB04_RS03170	COG2856	Zn peptidase
OB04_RS03180	COG1396	sequence-specific DNA binding
OB04_RS03240	COG3935	DnaD domain protein
OB04_RS03245	COG1484	DNA-dependent DNA replication
OB04_RS03340	COG3677	Transposase
OB04_RS03355	COG5484	DNA packaging
OB04_RS03360	COG1783	phage Terminase large subunit
OB04_RS03480	COG3409	Peptidoglycan-binding domain 1 protein
OB04_RS03480	COG5632	N-Acetylmuramoyl-L-alanine amidase
OB04_RS03505	COG1073	alpha beta
OB04_RS03510	COG0457	Tetratricopeptide repeat
OB04_RS03515	COG1063	alcohol dehydrogenase
OB04_RS03520	COG2211	Major facilitator Superfamily
OB04_RS03525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OB04_RS03530	COG1842	Phage shock protein A
OB04_RS03535	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OB04_RS03540	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
OB04_RS03545	COG4260	virion core protein, lumpy skin disease virus
OB04_RS03555	COG2814	Major facilitator Superfamily
OB04_RS03560	COG1063	alcohol dehydrogenase
OB04_RS03565	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OB04_RS03570	COG0823	Involved in the tonB-independent uptake of proteins
OB04_RS03585	COG2267	carboxylic ester hydrolase activity
OB04_RS03595	COG2132	Multicopper oxidase
OB04_RS03600	COG1113	amino acid transport
OB04_RS03610	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OB04_RS03615	COG0714	Associated with various cellular activities
OB04_RS03620	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
OB04_RS03625	COG1305	Transglutaminase-like
OB04_RS03630	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OB04_RS03630	COG0519	Catalyzes the synthesis of GMP from XMP
OB04_RS03635	COG2252	PERMEase
OB04_RS03640	COG3064	Membrane
OB04_RS03650	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
OB04_RS03660	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
OB04_RS03665	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OB04_RS03670	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OB04_RS03675	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
OB04_RS03680	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OB04_RS03685	COG0047	phosphoribosylformylglycinamidine synthase activity
OB04_RS03690	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OB04_RS03695	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
OB04_RS03700	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
OB04_RS03705	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OB04_RS03710	COG0138	bifunctional purine biosynthesis protein purh
OB04_RS03715	COG0151	Belongs to the GarS family
OB04_RS03720	COG1522	sequence-specific DNA binding
OB04_RS03725	COG0531	amino acid
OB04_RS03735	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OB04_RS03740	COG1470	cell adhesion involved in biofilm formation
OB04_RS03745	COG4496	protein, YerC YecD
OB04_RS03750	COG0069	glutamate synthase activity
OB04_RS03760	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
OB04_RS03765	COG0210	DNA helicase
OB04_RS03770	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OB04_RS03775	COG4851	CamS sex pheromone cAM373 precursor
OB04_RS03780	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OB04_RS03785	COG1285	pathogenesis
OB04_RS03790	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OB04_RS03795	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OB04_RS03800	COG0154	amidase activity
OB04_RS03805	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OB04_RS03810	COG1309	transcriptional regulator
OB04_RS03815	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OB04_RS03820	COG1597	lipid kinase activity
OB04_RS03825	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OB04_RS03830	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
OB04_RS03840	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
OB04_RS03860	COG5444	nuclease activity
OB04_RS03865	COG3391	amine dehydrogenase activity
OB04_RS03870	COG0457	Tetratricopeptide repeat
OB04_RS03880	COG0217	transcriptional regulatory protein
OB04_RS03890	COG1309	transcriptional regulator
OB04_RS03895	COG3631	Ketosteroid isomerase-related protein
OB04_RS03900	COG0702	epimerase
OB04_RS03915	COG3546	catalase activity
OB04_RS03920	COG0454	-acetyltransferase
OB04_RS03930	COG5578	integral membrane protein
OB04_RS03935	COG2972	Histidine kinase
OB04_RS03940	COG4753	response regulator
OB04_RS03940	COG2207	Transcriptional regulator
OB04_RS03945	COG1653	transport
OB04_RS03950	COG1175	transmembrane transport
OB04_RS03955	COG0395	ABC-type sugar transport system, permease component
OB04_RS03960	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
OB04_RS03965	COG2207	Transcriptional regulator
OB04_RS03970	COG2755	lipolytic protein G-D-S-L family
OB04_RS03980	COG5578	integral membrane protein
OB04_RS03985	COG3401	FG-GAP repeat protein
OB04_RS03990	COG3401	FG-GAP repeat protein
OB04_RS03995	COG2755	lipolytic protein G-D-S-L family
OB04_RS04000	COG1874	Beta-galactosidase
OB04_RS04010	COG1653	transport
OB04_RS04015	COG4209	transmembrane transport
OB04_RS04020	COG0395	ABC-type sugar transport system, permease component
OB04_RS04025	COG1486	melibiose metabolic process
OB04_RS04030	COG2323	membrane
OB04_RS04035	COG2329	Antibiotic biosynthesis monooxygenase
OB04_RS04040	COG0346	lactoylglutathione lyase activity
OB04_RS04060	COG0670	Belongs to the BI1 family
OB04_RS04065	COG0697	spore germination
OB04_RS04070	COG1846	Transcriptional regulator
OB04_RS04075	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OB04_RS04085	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OB04_RS04085	COG2124	cytochrome p450
OB04_RS04090	COG1368	sulfuric ester hydrolase activity
OB04_RS04095	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OB04_RS04100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OB04_RS04105	COG1442	glycosyl transferase family 8
OB04_RS04110	COG1216	Glycosyl transferase, family 2
OB04_RS04115	COG1442	glycosyl transferase family 8
OB04_RS04120	COG2223	nitrite transmembrane transporter activity
OB04_RS04125	COG1011	Hydrolase
OB04_RS04130	COG0531	amino acid
OB04_RS04135	COG1012	belongs to the aldehyde dehydrogenase family
OB04_RS04140	COG0840	transmembrane signaling receptor activity
OB04_RS04145	COG0488	(ABC) transporter
OB04_RS04155	COG0789	Transcriptional regulator
OB04_RS04160	COG2814	Major facilitator Superfamily
OB04_RS04175	COG0488	(ABC) transporter
OB04_RS04180	COG0513	Belongs to the DEAD box helicase family
OB04_RS04185	COG0456	acetyltransferase
OB04_RS04190	COG2130	NADP-dependent
OB04_RS04195	COG1120	ATPase activity
OB04_RS04200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OB04_RS04205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OB04_RS04210	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
OB04_RS04225	COG3866	Pectate lyase
OB04_RS04230	COG0471	metal ion transport
OB04_RS04235	COG3290	protein histidine kinase activity
OB04_RS04240	COG4565	transcriptional regulatory protein
OB04_RS04245	COG3181	Tripartite tricarboxylate transporter family receptor
OB04_RS04255	COG2851	Citrate transporter
OB04_RS04260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OB04_RS04265	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
OB04_RS04270	COG1254	Belongs to the acylphosphatase family
OB04_RS04275	COG2258	MOSC domain
OB04_RS04295	COG0024	Methionine aminopeptidase
OB04_RS04300	COG1263	PTS System
OB04_RS04300	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OB04_RS04305	COG1368	sulfuric ester hydrolase activity
OB04_RS04315	COG1115	amino acid carrier protein
OB04_RS04320	COG0531	amino acid
OB04_RS04335	COG0697	spore germination
OB04_RS04340	COG1263	PTS System
OB04_RS04340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OB04_RS04345	COG0366	Alpha amylase catalytic
OB04_RS04350	COG2188	Transcriptional regulator
OB04_RS04355	COG0778	Nitroreductase
OB04_RS04360	COG0737	Belongs to the 5'-nucleotidase family
OB04_RS04365	COG0693	protein deglycase activity
OB04_RS04370	COG2814	Major facilitator Superfamily
OB04_RS04375	COG4840	Belongs to the UPF0435 family
OB04_RS04380	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OB04_RS04385	COG4980	gas vesicle protein
OB04_RS04390	COG1295	ribonuclease BN
OB04_RS04400	COG0477	Major facilitator Superfamily
OB04_RS04410	COG0387	Pfam Sodium calcium exchanger
OB04_RS04420	COG0668	transmembrane transport
OB04_RS04425	COG0535	radical SAM domain protein
OB04_RS04435	COG0726	polysaccharide deacetylase
OB04_RS04440	COG2084	Dehydrogenase
OB04_RS04445	COG0598	Magnesium transport protein CorA
OB04_RS04450	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
OB04_RS04455	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OB04_RS04465	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OB04_RS04470	COG4637	Psort location Cytoplasmic, score
OB04_RS04475	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OB04_RS04480	COG0022	dehydrogenase e1 component
OB04_RS04485	COG0508	dehydrogenase complex catalyzes the overall conversion of
OB04_RS04490	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OB04_RS04495	COG3284	Transcriptional regulator
OB04_RS04505	COG1742	UPF0060 membrane protein
OB04_RS04525	COG4842	Belongs to the WXG100 family
OB04_RS04530	COG1486	melibiose metabolic process
OB04_RS04535	COG1737	Transcriptional regulator
OB04_RS04540	COG1263	PTS System
OB04_RS04540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OB04_RS04545	COG1132	(ABC) transporter
OB04_RS04550	COG1132	(ABC) transporter
OB04_RS04555	COG2259	Doxx family
OB04_RS04560	COG2514	catechol 2,3-dioxygenase activity
OB04_RS04565	COG4585	Histidine kinase
OB04_RS04570	COG2197	response regulator
OB04_RS04575	COG1131	(ABC) transporter
OB04_RS04580	COG1511	domain protein
OB04_RS04580	COG0842	Transport permease protein
OB04_RS04585	COG0842	Transport permease protein
OB04_RS04590	COG1695	Transcriptional regulator
OB04_RS04595	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
OB04_RS04600	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
OB04_RS04605	COG1309	transcriptional regulator
OB04_RS04610	COG2814	Major facilitator Superfamily
OB04_RS04620	COG2814	Major facilitator Superfamily
OB04_RS04625	COG1846	Transcriptional regulator
OB04_RS04630	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
OB04_RS04630	COG0392	lysyltransferase activity
OB04_RS04635	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OB04_RS04640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OB04_RS04645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OB04_RS04650	COG0384	phenazine biosynthesis protein PhzF
OB04_RS04655	COG0778	Nitroreductase
OB04_RS04670	COG1090	epimerase
OB04_RS04675	COG2137	regulation of response to DNA damage stimulus
OB04_RS04690	COG2814	Major facilitator Superfamily
OB04_RS04705	COG3103	Sh3 type 3 domain protein
OB04_RS04710	COG5658	integral membrane protein
OB04_RS04715	COG0596	Alpha beta hydrolase
OB04_RS04720	COG0463	Glycosyl transferase, family 2
OB04_RS04725	COG4485	Bacterial membrane protein, YfhO
OB04_RS04730	COG1988	membrane-bound metal-dependent
OB04_RS04735	COG1194	a g-specific adenine glycosylase
OB04_RS04745	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_RS04760	COG3557	Belongs to the UPF0374 family
OB04_RS04765	COG1132	(ABC) transporter
OB04_RS04770	COG4129	membrane
OB04_RS04775	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OB04_RS04780	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OB04_RS04785	COG0735	belongs to the Fur family
OB04_RS04900	COG4326	sporulation control protein
OB04_RS04915	COG3340	Belongs to the peptidase S51 family
OB04_RS04920	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
OB04_RS04925	COG0277	FAD linked oxidase domain protein
OB04_RS04935	COG0753	catalase activity
OB04_RS04940	COG1116	anion transmembrane transporter activity
OB04_RS04945	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OB04_RS04950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OB04_RS04955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OB04_RS04965	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OB04_RS04975	COG1476	TRANSCRIPTIONal
OB04_RS04985	COG3382	B3 4 domain protein
OB04_RS04990	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OB04_RS05000	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OB04_RS05005	COG0789	Transcriptional regulator
OB04_RS05010	COG1664	Polymer-forming cytoskeletal
OB04_RS05015	COG1664	Polymer-forming cytoskeletal
OB04_RS05020	COG2766	serine protein kinase
OB04_RS05025	COG2718	Belongs to the UPF0229 family
OB04_RS05035	COG1846	Transcriptional regulator
OB04_RS05040	COG1566	PFAM secretion protein HlyD family protein
OB04_RS05045	COG2814	Major facilitator Superfamily
OB04_RS05050	COG0655	NAD(P)H dehydrogenase (quinone) activity
OB04_RS05065	COG1725	Transcriptional regulator
OB04_RS05070	COG1131	(ABC) transporter
OB04_RS05075	COG1131	(ABC) transporter
OB04_RS05080	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
OB04_RS05085	COG1278	Cold shock
OB04_RS05095	COG1464	Belongs to the NlpA lipoprotein family
OB04_RS05100	COG3706	GGDEF domain
OB04_RS05105	COG1823	symporter activity
OB04_RS05125	COG5577	PFAM Coat F domain
OB04_RS05130	COG0737	Belongs to the 5'-nucleotidase family
OB04_RS05130	COG1525	nuclease
OB04_RS05130	COG4085	toxin activity
OB04_RS05135	COG3764	Sortase (surface protein transpeptidase)
OB04_RS05140	COG0564	pseudouridine synthase activity
OB04_RS05150	COG0517	IMP dehydrogenase activity
OB04_RS05155	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OB04_RS05160	COG3153	acetyltransferase
OB04_RS05160	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OB04_RS05165	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OB04_RS05170	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
OB04_RS05175	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OB04_RS05180	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OB04_RS05185	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OB04_RS05190	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OB04_RS05195	COG2203	Gaf domain
OB04_RS05195	COG4585	Histidine kinase
OB04_RS05200	COG2197	response regulator
OB04_RS05205	COG0431	NADPH-dependent FMN reductase
OB04_RS05220	COG1388	LysM domain
OB04_RS05220	COG0791	NLP P60 protein
OB04_RS05225	COG1959	2 iron, 2 sulfur cluster binding
OB04_RS05230	COG0668	transmembrane transport
OB04_RS05235	COG2719	SpoVR family
OB04_RS05240	COG1785	Belongs to the alkaline phosphatase family
OB04_RS05245	COG1388	LysM domain
OB04_RS05245	COG0791	NLP P60 protein
OB04_RS05250	COG0583	DNA-binding transcription factor activity
OB04_RS05255	COG0372	Belongs to the citrate synthase family
OB04_RS05260	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_RS05265	COG0531	amino acid
OB04_RS05270	COG0733	neurotransmitter:sodium symporter activity
OB04_RS05275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OB04_RS05280	COG0456	acetyltransferase
OB04_RS05295	COG1595	DNA-templated transcription, initiation
OB04_RS05300	COG0667	Aldo Keto reductase
OB04_RS05305	COG0204	Acyl-transferase
OB04_RS05310	COG1253	flavin adenine dinucleotide binding
OB04_RS05315	COG0789	Transcriptional regulator
OB04_RS05320	COG0436	Aminotransferase
OB04_RS05325	COG1253	flavin adenine dinucleotide binding
OB04_RS05330	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OB04_RS05335	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OB04_RS05340	COG0584	glycerophosphoryl diester phosphodiesterase
OB04_RS05350	COG0668	transmembrane transport
OB04_RS05355	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OB04_RS05360	COG0726	polysaccharide deacetylase
OB04_RS05365	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OB04_RS05370	COG1757	Na H antiporter
OB04_RS05375	COG0589	response to stress
OB04_RS05385	COG1132	(ABC) transporter
OB04_RS05390	COG1132	(ABC) transporter
OB04_RS05395	COG0702	epimerase
OB04_RS05410	COG0189	ligase activity
OB04_RS05415	COG0189	ligase activity
OB04_RS05420	COG4399	Belongs to the UPF0754 family
OB04_RS05425	COG3679	Belongs to the UPF0342 family
OB04_RS05430	COG4335	DNA alkylation repair
OB04_RS05435	COG0561	phosphatase activity
OB04_RS05440	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OB04_RS05445	COG0475	glutathione-regulated potassium exporter activity
OB04_RS05450	COG0490	domain, Protein
OB04_RS05460	COG1024	Enoyl-CoA hydratase
OB04_RS05470	COG4152	abc transporter atp-binding protein
OB04_RS05475	COG1668	transmembrane transport
OB04_RS05480	COG0420	3'-5' exonuclease activity
OB04_RS05485	COG4717	serine-type aminopeptidase activity
OB04_RS05490	COG3481	metal-dependent phosphohydrolase, HD sub domain
OB04_RS05500	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OB04_RS05525	COG1846	Transcriptional regulator
OB04_RS05530	COG4980	gas vesicle protein
OB04_RS05545	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
OB04_RS05550	COG0537	adenosine 5'-monophosphoramidase activity
OB04_RS05555	COG1131	(ABC) transporter
OB04_RS05560	COG4473	ABC transporter
OB04_RS05570	COG1473	amidohydrolase
OB04_RS05575	COG3069	C4-dicarboxylate transmembrane transporter activity
OB04_RS05585	COG2329	Antibiotic biosynthesis monooxygenase
OB04_RS05590	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OB04_RS05595	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OB04_RS05600	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
OB04_RS05605	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
OB04_RS05610	COG1309	transcriptional regulator
OB04_RS05615	COG1511	domain protein
OB04_RS05620	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OB04_RS05625	COG4377	Putative membrane peptidase family (DUF2324)
OB04_RS05635	COG1363	Peptidase, m42
OB04_RS05640	COG4405	Protein conserved in bacteria
OB04_RS05645	COG1301	dicarboxylic acid transport
OB04_RS05655	COG1234	tRNA 3'-trailer cleavage
OB04_RS05660	COG0095	Lipoate-protein ligase
OB04_RS05665	COG0702	epimerase
OB04_RS05670	COG0318	PFAM AMP-dependent synthetase and ligase
OB04_RS05680	COG0501	Belongs to the peptidase M48B family
OB04_RS05690	COG0456	acetyltransferase
OB04_RS05695	COG0604	alcohol dehydrogenase
OB04_RS05700	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
OB04_RS05705	COG0406	alpha-ribazole phosphatase activity
OB04_RS05710	COG0183	Belongs to the thiolase family
OB04_RS05715	COG0318	PFAM AMP-dependent synthetase and ligase
OB04_RS05720	COG1268	BioY protein
OB04_RS05725	COG0840	transmembrane signaling receptor activity
OB04_RS05730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OB04_RS05730	COG0723	plastoquinol--plastocyanin reductase activity
OB04_RS05735	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_RS05745	COG4903	ComK protein
OB04_RS05750	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_RS05760	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OB04_RS05775	COG0398	Pfam SNARE associated Golgi protein
OB04_RS05780	COG0681	Belongs to the peptidase S26 family
OB04_RS05785	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OB04_RS05790	COG1846	Transcriptional regulator
OB04_RS05795	COG0738	Major facilitator superfamily
OB04_RS05800	COG0673	inositol 2-dehydrogenase activity
OB04_RS05805	COG0561	phosphatase activity
OB04_RS05810	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OB04_RS05815	COG1609	Transcriptional regulator
OB04_RS05820	COG3180	Ammonia monooxygenase
OB04_RS05825	COG2814	Major facilitator Superfamily
OB04_RS05825	COG0477	Major facilitator Superfamily
OB04_RS05830	COG4533	DNA binding
OB04_RS05840	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
OB04_RS05845	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
OB04_RS05850	COG1074	ATP-dependent DNA helicase activity
OB04_RS05855	COG0420	3'-5' exonuclease activity
OB04_RS05860	COG0419	ATPase involved in DNA repair
OB04_RS05865	COG1403	HNH endonuclease
OB04_RS05910	COG5337	Spore coat protein CotH
OB04_RS05915	COG0179	Fumarylacetoacetate (FAA) hydrolase
OB04_RS05925	COG1404	Belongs to the peptidase S8 family
OB04_RS05935	COG0367	asparagine synthase
OB04_RS05940	COG2318	DinB family
OB04_RS05945	COG1562	ergosterol biosynthetic process
OB04_RS05950	COG0534	Mate efflux family protein
OB04_RS05955	COG2207	Transcriptional regulator
OB04_RS05955	COG1917	Cupin 2, conserved barrel domain protein
OB04_RS05960	COG1609	Transcriptional regulator
OB04_RS05965	COG0673	inositol 2-dehydrogenase activity
OB04_RS05970	COG2318	DinB family
OB04_RS05980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OB04_RS05985	COG1357	PFAM Pentapeptide repeats (8 copies)
OB04_RS05990	COG2267	carboxylic ester hydrolase activity
OB04_RS05995	COG0529	Catalyzes the synthesis of activated sulfate
OB04_RS06000	COG2046	Belongs to the sulfate adenylyltransferase family
OB04_RS06005	COG0175	sulfate reduction
OB04_RS06010	COG2045	Belongs to the ComB family
OB04_RS06015	COG1809	phosphosulfolactate synthase activity
OB04_RS06020	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OB04_RS06025	COG4948	Mandelate Racemase Muconate Lactonizing
OB04_RS06030	COG2814	Major facilitator Superfamily
OB04_RS06035	COG0454	-acetyltransferase
OB04_RS06040	COG2153	protein acetylation
OB04_RS06045	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
OB04_RS06045	COG0646	methionine synthase
OB04_RS06050	COG1666	GTP binding
OB04_RS06055	COG2996	Protein conserved in bacteria
OB04_RS06075	COG1695	Transcriptional regulator
OB04_RS06090	COG3227	Zinc metalloprotease (Elastase)
OB04_RS06095	COG1307	EDD domain protein, DegV family
OB04_RS06100	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OB04_RS06120	COG0561	phosphatase activity
OB04_RS06125	COG1073	alpha beta
OB04_RS06130	COG2151	metal-sulfur cluster biosynthetic enzyme
OB04_RS06140	COG0277	FAD linked oxidase domain protein
OB04_RS06145	COG2271	Major facilitator Superfamily
OB04_RS06150	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OB04_RS06155	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OB04_RS06165	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OB04_RS06170	COG0505	Belongs to the CarA family
OB04_RS06175	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
OB04_RS06180	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OB04_RS06195	COG2267	carboxylic ester hydrolase activity
OB04_RS06205	COG1744	ABC transporter substrate-binding protein PnrA-like
OB04_RS06220	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OB04_RS06225	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OB04_RS06230	COG5504	Zn-dependent protease
OB04_RS06235	COG0444	Belongs to the ABC transporter superfamily
OB04_RS06240	COG4608	Belongs to the ABC transporter superfamily
OB04_RS06250	COG0601	transmembrane transport
OB04_RS06255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OB04_RS06265	COG0180	Tryptophanyl-tRNA synthetase
OB04_RS06270	COG4166	transmembrane transport
OB04_RS06275	COG0601	transmembrane transport
OB04_RS06280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OB04_RS06285	COG0444	Belongs to the ABC transporter superfamily
OB04_RS06290	COG4608	Belongs to the ABC transporter superfamily
OB04_RS06295	COG2814	Major facilitator Superfamily
OB04_RS06300	COG0456	acetyltransferase
OB04_RS06305	COG1393	Belongs to the ArsC family
OB04_RS06310	COG0861	Integral membrane protein TerC family
OB04_RS06315	COG4862	establishment of competence for transformation
OB04_RS06320	COG4469	Competence protein
OB04_RS06325	COG1164	Oligoendopeptidase f
OB04_RS06340	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OB04_RS06345	COG2346	COG2346, Truncated hemoglobins
OB04_RS06350	COG0741	lytic transglycosylase activity
OB04_RS06355	COG4116	CYTH
OB04_RS06365	COG2357	RelA SpoT domain protein
OB04_RS06370	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OB04_RS06375	COG0564	pseudouridine synthase activity
OB04_RS06380	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OB04_RS06385	COG0569	domain protein
OB04_RS06385	COG0475	glutathione-regulated potassium exporter activity
OB04_RS06390	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OB04_RS06395	COG0352	thiamine-phosphate diphosphorylase activity
OB04_RS06400	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OB04_RS06405	COG2104	thiamine diphosphate biosynthetic process
OB04_RS06410	COG2022	thiamine diphosphate biosynthetic process
OB04_RS06415	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OB04_RS06420	COG0351	phosphomethylpyrimidine kinase
OB04_RS06425	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
OB04_RS06485	COG0210	DNA helicase
OB04_RS06495	COG2153	protein acetylation
OB04_RS06500	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
OB04_RS06505	COG2382	esterase
OB04_RS06510	COG0626	cystathionine gamma-synthase activity
OB04_RS06515	COG0626	cystathionine gamma-synthase activity
OB04_RS06520	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OB04_RS06525	COG5505	Protein of unknown function (DUF819)
OB04_RS06545	COG5444	nuclease activity
OB04_RS06565	COG0457	Tetratricopeptide repeat
OB04_RS06570	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
OB04_RS06575	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_RS06585	COG3711	transcriptional antiterminator
OB04_RS06585	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OB04_RS06590	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OB04_RS06590	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OB04_RS06590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OB04_RS06595	COG1482	cell wall glycoprotein biosynthetic process
OB04_RS06605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OB04_RS06615	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OB04_RS06630	COG0109	protoheme IX farnesyltransferase activity
OB04_RS06640	COG0726	polysaccharide deacetylase
OB04_RS06660	COG5504	Zn-dependent protease
OB04_RS06665	COG2205	protein histidine kinase activity
OB04_RS06675	COG3383	formate dehydrogenase (NAD+) activity
OB04_RS06680	COG2427	Protein of unknown function (DUF1641)
OB04_RS06690	COG1051	belongs to the nudix hydrolase family
OB04_RS06700	COG2124	cytochrome p450
OB04_RS06705	COG1819	glycosyl
OB04_RS06715	COG1587	Uroporphyrinogen-III synthase
OB04_RS06720	COG0390	transport system, permease component
OB04_RS06725	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OB04_RS06730	COG0697	spore germination
OB04_RS06735	COG4297	protein containing double-stranded beta helix domain
OB04_RS06745	COG1252	NADH dehydrogenase
OB04_RS06750	COG1904	glucuronate isomerase
OB04_RS06755	COG2211	Major facilitator Superfamily
OB04_RS06760	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
OB04_RS06765	COG1063	alcohol dehydrogenase
OB04_RS06770	COG1312	Catalyzes the dehydration of D-mannonate
OB04_RS06775	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_RS06780	COG2271	Major facilitator Superfamily
OB04_RS06785	COG1609	Transcriptional regulator
OB04_RS06790	COG0246	Mannitol dehydrogenase
OB04_RS06795	COG2721	sulfolactate sulfo-lyase activity
OB04_RS06800	COG0730	response to heat
OB04_RS06805	COG2318	DinB family
OB04_RS06810	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OB04_RS06815	COG0457	Tetratricopeptide repeat
OB04_RS06825	COG2350	Protein conserved in bacteria
OB04_RS06830	COG3409	Peptidoglycan-binding domain 1 protein
OB04_RS06830	COG1388	LysM domain
OB04_RS06830	COG5632	N-Acetylmuramoyl-L-alanine amidase
OB04_RS06840	COG4195	phage-related replication protein
OB04_RS06845	COG3546	catalase activity
OB04_RS06850	COG2856	Zn peptidase
OB04_RS06855	COG1396	sequence-specific DNA binding
OB04_RS06865	COG1522	sequence-specific DNA binding
OB04_RS06870	COG1484	DNA-dependent DNA replication
OB04_RS06895	COG1595	DNA-templated transcription, initiation
OB04_RS06900	COG3728	DNA packaging
OB04_RS06900	COG5484	DNA packaging
OB04_RS06905	COG1783	phage Terminase large subunit
OB04_RS06910	COG5518	Phage portal protein
OB04_RS06915	COG0338	D12 class N6 adenine-specific DNA methyltransferase
OB04_RS06920	COG4653	Phage capsid family
OB04_RS06975	COG1652	LysM domain
OB04_RS06980	COG4193	domain, Protein
OB04_RS06990	COG3628	GPW Gp25 family protein
OB04_RS06995	COG3299	homolog of phage Mu protein gp47
OB04_RS07000	COG3778	Protein conserved in bacteria
OB04_RS07040	COG5632	N-Acetylmuramoyl-L-alanine amidase
OB04_RS07040	COG3409	Peptidoglycan-binding domain 1 protein
OB04_RS07055	COG0306	phosphate transporter
OB04_RS07060	COG1392	Phosphate transport regulator
OB04_RS07065	COG0531	amino acid
OB04_RS07070	COG0346	lactoylglutathione lyase activity
OB04_RS07075	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OB04_RS07080	COG0463	Glycosyl transferase, family 2
OB04_RS07090	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OB04_RS07095	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OB04_RS07100	COG2362	D-Aminopeptidase
OB04_RS07105	COG0601	transmembrane transport
OB04_RS07110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OB04_RS07115	COG0444	Belongs to the ABC transporter superfamily
OB04_RS07120	COG4166	transmembrane transport
OB04_RS07125	COG1619	proteins homologs of microcin C7 resistance protein MccF
OB04_RS07130	COG4948	Mandelate Racemase Muconate Lactonizing
OB04_RS07135	COG0791	NLP P60 protein
OB04_RS07140	COG4608	Belongs to the ABC transporter superfamily
OB04_RS07145	COG2706	6-phosphogluconolactonase activity
OB04_RS07150	COG1834	amidinotransferase
OB04_RS07155	COG1607	acyl-coa hydrolase
OB04_RS07160	COG1017	nitric oxide dioxygenase activity
OB04_RS07160	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OB04_RS07170	COG2323	membrane
OB04_RS07175	COG2318	DinB family
OB04_RS07180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OB04_RS07185	COG2076	Multidrug Resistance protein
OB04_RS07190	COG2076	Multidrug Resistance protein
OB04_RS07195	COG0788	formyltetrahydrofolate deformylase activity
OB04_RS07200	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OB04_RS07205	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OB04_RS07210	COG1764	response to oxidative stress
OB04_RS07215	COG1846	Transcriptional regulator
OB04_RS07220	COG1764	response to oxidative stress
OB04_RS07230	COG0590	tRNA wobble adenosine to inosine editing
OB04_RS07235	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OB04_RS07240	COG1404	Belongs to the peptidase S8 family
OB04_RS07245	COG1366	Belongs to the anti-sigma-factor antagonist family
OB04_RS07250	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OB04_RS07255	COG1122	ATPase activity
OB04_RS07260	COG4721	ABC-type cobalt transport system, permease component
OB04_RS07270	COG0745	RESPONSE REGULATOR receiver
OB04_RS07275	COG3850	Histidine kinase
OB04_RS07275	COG5002	protein histidine kinase activity
OB04_RS07280	COG3212	peptidase
OB04_RS07285	COG3212	peptidase
OB04_RS07305	COG2239	Acts as a magnesium transporter
OB04_RS07310	COG0789	Transcriptional regulator
OB04_RS07325	COG1846	Transcriptional regulator
OB04_RS07330	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OB04_RS07335	COG0726	polysaccharide deacetylase
OB04_RS07340	COG1408	metallophosphoesterase
OB04_RS07350	COG0463	Glycosyl transferase, family 2
OB04_RS07355	COG1793	dna ligase
OB04_RS07355	COG3285	dna ligase
OB04_RS07360	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
OB04_RS07365	COG5001	Diguanylate cyclase
OB04_RS07365	COG3300	MHYT domain
OB04_RS07370	COG0586	Pfam SNARE associated Golgi protein
OB04_RS07375	COG0861	Integral membrane protein TerC family
OB04_RS07380	COG1191	sigma factor activity
OB04_RS07400	COG0501	Belongs to the peptidase M48B family
OB04_RS07405	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OB04_RS07420	COG3594	Acyltransferase
OB04_RS07425	COG5002	protein histidine kinase activity
OB04_RS07430	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OB04_RS07440	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
OB04_RS07445	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
OB04_RS07450	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OB04_RS07455	COG0436	Aminotransferase
OB04_RS07460	COG1850	ribulose-bisphosphate carboxylase activity
OB04_RS07465	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
OB04_RS07470	COG0235	Class ii aldolase
OB04_RS07475	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
OB04_RS07480	COG3339	Conserved Protein
OB04_RS07495	COG3852	Histidine kinase
OB04_RS07500	COG1846	Transcriptional regulator
OB04_RS07505	COG1360	Flagellar Motor Protein
OB04_RS07510	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
OB04_RS07515	COG0542	response to heat
OB04_RS07520	COG3949	Membrane
OB04_RS07525	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OB04_RS07530	COG0720	synthase
OB04_RS07535	COG0602	queuosine metabolic process
OB04_RS07540	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OB04_RS07545	COG1733	regulation of RNA biosynthetic process
OB04_RS07550	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_RS07555	COG4641	Protein conserved in bacteria
OB04_RS07555	COG1388	LysM domain
OB04_RS07560	COG1388	LysM domain
OB04_RS07565	COG3858	chitin binding
OB04_RS07575	COG4873	Protein conserved in bacteria
OB04_RS07590	COG3773	Cell wall hydrolase
OB04_RS07595	COG2244	polysaccharide biosynthetic process
OB04_RS07600	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OB04_RS07605	COG2217	Heavy metal translocating P-type atpase
OB04_RS07615	COG0006	proline dipeptidase activity
OB04_RS07625	COG1609	Transcriptional regulator
OB04_RS07630	COG3711	transcriptional antiterminator
OB04_RS07635	COG1263	PTS System
OB04_RS07635	COG2190	(PTS) system
OB04_RS07635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OB04_RS07640	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OB04_RS07645	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OB04_RS07655	COG1533	DNA photolyase activity
OB04_RS07660	COG0456	acetyltransferase
OB04_RS07665	COG0840	transmembrane signaling receptor activity
OB04_RS07670	COG2084	Dehydrogenase
OB04_RS07675	COG2340	Cysteine-rich secretory protein family
OB04_RS07680	COG0768	penicillin binding
OB04_RS07685	COG4191	Histidine kinase
OB04_RS07690	COG0436	Aminotransferase
OB04_RS07700	COG0835	chemotaxis
OB04_RS07700	COG0784	Response regulator, receiver
OB04_RS07710	COG2814	Major facilitator Superfamily
OB04_RS07715	COG1376	ErfK ybiS ycfS ynhG family protein
OB04_RS07720	COG1408	metallophosphoesterase
OB04_RS07725	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_RS07730	COG2200	EAL domain
OB04_RS07740	COG4703	Protein of unknown function (DUF1797)
OB04_RS07745	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
OB04_RS07755	COG0517	IMP dehydrogenase activity
OB04_RS07760	COG0583	DNA-binding transcription factor activity
OB04_RS07765	COG0716	FMN binding
OB04_RS07775	COG0716	FMN binding
OB04_RS07780	COG2171	N-acyltransferase activity
OB04_RS07785	COG1473	amidohydrolase
OB04_RS07795	COG0668	transmembrane transport
OB04_RS07800	COG0450	alkyl hydroperoxide reductase
OB04_RS07805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OB04_RS07820	COG0746	molybdenum cofactor guanylyltransferase activity
OB04_RS07825	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OB04_RS07830	COG0303	'Molybdopterin
OB04_RS07835	COG1763	Mo-molybdopterin cofactor biosynthetic process
OB04_RS07840	COG0314	molybdopterin synthase activity
OB04_RS07845	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
OB04_RS07850	COG1132	(ABC) transporter
OB04_RS07855	COG1132	(ABC) transporter
OB04_RS07865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OB04_RS07870	COG1136	(ABC) transporter
OB04_RS07875	COG0577	efflux transmembrane transporter activity
OB04_RS07880	COG1349	DNA-binding transcription factor activity
OB04_RS07885	COG1105	Belongs to the carbohydrate kinase PfkB family
OB04_RS07890	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OB04_RS07890	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OB04_RS07890	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OB04_RS07895	COG0681	Belongs to the peptidase S26 family
OB04_RS07905	COG0488	(ABC) transporter
OB04_RS07910	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OB04_RS07915	COG2309	aminopeptidase activity
OB04_RS07925	COG1077	Cell shape determining protein MreB Mrl
OB04_RS07930	COG2002	toxin-antitoxin pair type II binding
OB04_RS07935	COG3852	Histidine kinase
OB04_RS07940	COG2105	PFAM AIG2 family protein
OB04_RS07940	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
OB04_RS07945	COG0569	domain protein
OB04_RS07950	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OB04_RS07955	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OB04_RS07960	COG5503	Protein of unknown function (DUF1447)
OB04_RS07965	COG0561	phosphatase activity
OB04_RS07970	COG0242	peptide deformylase activity
OB04_RS07980	COG0497	DNA recombination
OB04_RS07985	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OB04_RS07990	COG0022	dehydrogenase e1 component
OB04_RS07995	COG0508	dehydrogenase complex catalyzes the overall conversion of
OB04_RS08000	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OB04_RS08005	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OB04_RS08010	COG1982	Orn Lys Arg decarboxylase major
OB04_RS08015	COG4476	Belongs to the UPF0223 family
OB04_RS08020	COG4493	Belongs to the UPF0637 family
OB04_RS08030	COG0483	inositol monophosphate 1-phosphatase activity
OB04_RS08040	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
OB04_RS08060	COG1595	DNA-templated transcription, initiation
OB04_RS08080	COG1217	gtp-binding protein TYPA
OB04_RS08090	COG4896	Protein conserved in bacteria
OB04_RS08100	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
OB04_RS08105	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OB04_RS08110	COG2066	Belongs to the glutaminase family
OB04_RS08115	COG4838	Belongs to the UPF0358 family
OB04_RS08120	COG0772	Belongs to the SEDS family
OB04_RS08125	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
OB04_RS08130	COG1612	heme a metabolic process
OB04_RS08135	COG0109	protoheme IX farnesyltransferase activity
OB04_RS08140	COG2010	Cytochrome c
OB04_RS08140	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OB04_RS08145	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OB04_RS08150	COG1845	cytochrome c oxidase, subunit III
OB04_RS08155	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
OB04_RS08160	COG3336	cytochrome c oxidase
OB04_RS08170	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
OB04_RS08175	COG2340	Cysteine-rich secretory protein family
OB04_RS08190	COG3679	Belongs to the UPF0342 family
OB04_RS08195	COG4471	UPF0298 protein
OB04_RS08200	COG0742	ribosomal rna small subunit methyltransferase
OB04_RS08205	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OB04_RS08210	COG3314	Sporulation integral membrane protein YlbJ
OB04_RS08215	COG1752	Esterase of the alpha-beta hydrolase superfamily
OB04_RS08220	COG3480	Lon protease (S16) C-terminal proteolytic domain
OB04_RS08225	COG1323	Belongs to the UPF0348 family
OB04_RS08235	COG1399	metal-binding, possibly nucleic acid-binding protein
OB04_RS08250	COG0454	-acetyltransferase
OB04_RS08255	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OB04_RS08260	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
OB04_RS08265	COG2001	Belongs to the MraZ family
OB04_RS08270	COG0275	rRNA processing
OB04_RS08275	COG4839	cell division protein FtsL
OB04_RS08280	COG0768	penicillin binding
OB04_RS08290	COG0768	penicillin binding
OB04_RS08300	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OB04_RS08310	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OB04_RS08315	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OB04_RS08320	COG0772	Belongs to the SEDS family
OB04_RS08325	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OB04_RS08330	COG0812	UDP-N-acetylmuramate dehydrogenase activity
OB04_RS08335	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OB04_RS08340	COG3879	Bacterial protein of unknown function (DUF881)
OB04_RS08345	COG3879	Bacterial protein of unknown function (DUF881)
OB04_RS08350	COG3856	small basic protein
OB04_RS08355	COG0849	cell division
OB04_RS08360	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OB04_RS08365	COG4412	M6 family metalloprotease domain protein
OB04_RS08365	COG1404	Belongs to the peptidase S8 family
OB04_RS08375	COG1191	sigma factor activity
OB04_RS08380	COG1191	sigma factor activity
OB04_RS08385	COG1119	ATPase activity
OB04_RS08390	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OB04_RS08395	COG1873	PFAM PRC-barrel domain
OB04_RS08400	COG1496	oxidoreductase activity
OB04_RS08405	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OB04_RS08410	COG1799	cell septum assembly
OB04_RS08415	COG0762	integral membrane protein
OB04_RS08420	COG2302	S4 RNA-binding domain
OB04_RS08425	COG3599	regulation of cell shape
OB04_RS08430	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OB04_RS08435	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OB04_RS08440	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OB04_RS08445	COG0564	pseudouridine synthase activity
OB04_RS08450	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
OB04_RS08455	COG2233	PERMEase
OB04_RS08460	COG0540	Belongs to the ATCase OTCase family
OB04_RS08465	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OB04_RS08470	COG0505	Belongs to the CarA family
OB04_RS08475	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
OB04_RS08480	COG0543	2 iron, 2 sulfur cluster binding
OB04_RS08485	COG0167	dihydroorotate dehydrogenase activity
OB04_RS08490	COG0284	orotidine-5'-phosphate decarboxylase activity
OB04_RS08495	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OB04_RS08505	COG0175	sulfate reduction
OB04_RS08510	COG0306	phosphate transporter
OB04_RS08515	COG2046	Belongs to the sulfate adenylyltransferase family
OB04_RS08520	COG0529	Catalyzes the synthesis of activated sulfate
OB04_RS08525	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OB04_RS08530	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
OB04_RS08535	COG1648	precorrin-2 dehydrogenase activity
OB04_RS08540	COG1293	RNA-binding protein homologous to eukaryotic snRNP
OB04_RS08545	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
OB04_RS08550	COG1561	YicC-like family, N-terminal region
OB04_RS08560	COG0194	GDP metabolic process
OB04_RS08565	COG1758	RNA polymerase activity
OB04_RS08570	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OB04_RS08575	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OB04_RS08580	COG0242	peptide deformylase activity
OB04_RS08585	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OB04_RS08590	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OB04_RS08590	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OB04_RS08595	COG0820	rRNA (adenine-C2-)-methyltransferase activity
OB04_RS08600	COG0631	protein serine/threonine phosphatase activity
OB04_RS08605	COG2815	serine threonine protein kinase
OB04_RS08605	COG0515	serine threonine protein kinase
OB04_RS08610	COG1162	GTPase activity
OB04_RS08615	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OB04_RS08620	COG1564	THIamine pyrophosphokinase
OB04_RS08630	COG0227	Belongs to the bacterial ribosomal protein bL28 family
OB04_RS08635	COG1302	Protein conserved in bacteria
OB04_RS08640	COG1461	Dihydroxyacetone kinase
OB04_RS08645	COG1760	l-serine dehydratase
OB04_RS08650	COG1760	l-serine dehydratase
OB04_RS08655	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OB04_RS08660	COG2050	protein possibly involved in aromatic compounds catabolism
OB04_RS08660	COG1349	DNA-binding transcription factor activity
OB04_RS08665	COG0416	fatty acid biosynthetic process
OB04_RS08670	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OB04_RS08675	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_RS08685	COG0571	ribonuclease III activity
OB04_RS08690	COG1196	nuclear chromosome segregation
OB04_RS08695	COG0552	protein localization to endoplasmic reticulum
OB04_RS08705	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
OB04_RS08710	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OB04_RS08715	COG0228	four-way junction DNA binding
OB04_RS08720	COG1837	Belongs to the UPF0109 family
OB04_RS08730	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OB04_RS08735	COG0336	Belongs to the RNA methyltransferase TrmD family
OB04_RS08740	COG0335	large ribosomal subunit rRNA binding
OB04_RS08745	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OB04_RS08750	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OB04_RS08760	COG2257	FlhB HrpN YscU SpaS Family
OB04_RS08765	COG0045	succinate-CoA ligase (ADP-forming) activity
OB04_RS08770	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OB04_RS08775	COG0758	DNA mediated transformation
OB04_RS08780	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OB04_RS08785	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
OB04_RS08790	COG4974	Belongs to the 'phage' integrase family
OB04_RS08795	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
OB04_RS08800	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OB04_RS08805	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
OB04_RS08810	COG1815	bacterial-type flagellum-dependent cell motility
OB04_RS08815	COG1558	bacterial-type flagellum-dependent cell motility
OB04_RS08820	COG1677	Flagellar hook-basal body complex protein FliE
OB04_RS08825	COG1766	The M ring may be actively involved in energy transduction
OB04_RS08830	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OB04_RS08835	COG1317	bacterial-type flagellum organization
OB04_RS08840	COG1157	protein secretion by the type III secretion system
OB04_RS08845	COG2882	bacterial-type flagellum organization
OB04_RS08850	COG3334	PFAM MgtE intracellular
OB04_RS08855	COG3144	bacterial-type flagellum assembly
OB04_RS08860	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
OB04_RS08865	COG4786	Flagellar basal body rod
OB04_RS08870	COG1582	Flagellar protein (FlbD)
OB04_RS08875	COG1580	Controls the rotational direction of flagella during chemotaxis
OB04_RS08880	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OB04_RS08885	COG1776	CheC inhibitor of MCP methylation
OB04_RS08885	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OB04_RS08890	COG2201	protein-glutamate methylesterase activity
OB04_RS08895	COG3190	flagellar
OB04_RS08900	COG1338	Plays a role in the flagellum-specific transport system
OB04_RS08905	COG1987	bacterial-type flagellum assembly
OB04_RS08910	COG1684	flagellar biosynthetic protein fliR
OB04_RS08915	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OB04_RS08920	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OB04_RS08925	COG1419	protein localization to endoplasmic reticulum
OB04_RS08930	COG0455	bacterial-type flagellum organization
OB04_RS08935	COG2201	protein-glutamate methylesterase activity
OB04_RS08940	COG2198	Histidine kinase
OB04_RS08940	COG0643	Histidine kinase
OB04_RS08945	COG0835	chemotaxis
OB04_RS08950	COG1776	CheC inhibitor of MCP methylation
OB04_RS08955	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
OB04_RS08960	COG1191	sigma factor activity
OB04_RS08970	COG0052	Belongs to the universal ribosomal protein uS2 family
OB04_RS08975	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OB04_RS08980	COG0528	UMP kinase activity
OB04_RS08985	COG0233	cytoplasmic translational termination
OB04_RS08990	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OB04_RS08995	COG4589	Belongs to the CDS family
OB04_RS09000	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
OB04_RS09005	COG0750	zinc metalloprotease
OB04_RS09010	COG0442	prolyl-tRNA aminoacylation
OB04_RS09015	COG2176	DNA-directed DNA polymerase activity
OB04_RS09020	COG0779	Required for maturation of 30S ribosomal subunits
OB04_RS09025	COG0195	Participates in both transcription termination and antitermination
OB04_RS09030	COG2740	Nucleic-acid-binding protein implicated in transcription termination
OB04_RS09035	COG1358	cellular component organization or biogenesis
OB04_RS09040	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OB04_RS09045	COG1550	Protein conserved in bacteria
OB04_RS09050	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OB04_RS09055	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OB04_RS09060	COG0196	riboflavin kinase activity
OB04_RS09065	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OB04_RS09070	COG1185	polyribonucleotide nucleotidyltransferase activity
OB04_RS09075	COG0726	polysaccharide deacetylase
OB04_RS09080	COG0612	Peptidase, M16
OB04_RS09085	COG1873	PFAM PRC-barrel domain
OB04_RS09095	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OB04_RS09100	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OB04_RS09105	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OB04_RS09110	COG0527	aspartate kinase activity
OB04_RS09115	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OB04_RS09120	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OB04_RS09125	COG0740	serine-type endopeptidase activity
OB04_RS09135	COG4980	gas vesicle protein
OB04_RS09135	COG1674	ftsk spoiiie
OB04_RS09140	COG2188	Transcriptional regulator
OB04_RS09145	COG2814	Major facilitator Superfamily
OB04_RS09150	COG0612	Peptidase, M16
OB04_RS09155	COG0612	Peptidase, M16
OB04_RS09160	COG0300	oxidoreductase activity
OB04_RS09175	COG1426	Protein conserved in bacteria
OB04_RS09180	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OB04_RS09185	COG1058	Belongs to the CinA family
OB04_RS09185	COG1546	Belongs to the CinA family
OB04_RS09190	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OB04_RS09195	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OB04_RS09200	COG1418	mRNA catabolic process
OB04_RS09205	COG1692	metallophosphoesterase
OB04_RS09210	COG2359	stage V sporulation protein S
OB04_RS09215	COG1063	alcohol dehydrogenase
OB04_RS09220	COG0156	8-amino-7-oxononanoate synthase activity
OB04_RS09225	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OB04_RS09230	COG4550	Control of competence regulator ComK, YlbF/YmcA
OB04_RS09240	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OB04_RS09245	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OB04_RS09260	COG3226	Transcriptional regulator
OB04_RS09265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OB04_RS09275	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OB04_RS09280	COG3321	synthase
OB04_RS09285	COG2070	2-Nitropropane dioxygenase
OB04_RS09285	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OB04_RS09290	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OB04_RS09295	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OB04_RS09300	COG3425	synthase
OB04_RS09305	COG1024	Enoyl-CoA hydratase
OB04_RS09310	COG1024	Enoyl-CoA hydratase
OB04_RS09315	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_RS09315	COG3321	synthase
OB04_RS09315	COG0300	oxidoreductase activity
OB04_RS09315	COG0318	PFAM AMP-dependent synthetase and ligase
OB04_RS09315	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OB04_RS09320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OB04_RS09320	COG0300	oxidoreductase activity
OB04_RS09320	COG3321	synthase
OB04_RS09320	COG4221	oxidoreductase activity
OB04_RS09325	COG3321	synthase
OB04_RS09325	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_RS09325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OB04_RS09325	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OB04_RS09325	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OB04_RS09330	COG4221	oxidoreductase activity
OB04_RS09330	COG3321	synthase
OB04_RS09330	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_RS09330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OB04_RS09335	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
OB04_RS09335	COG3321	synthase
OB04_RS09335	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OB04_RS09335	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OB04_RS09340	COG2124	cytochrome p450
OB04_RS09350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OB04_RS09355	COG1404	Belongs to the peptidase S8 family
OB04_RS09365	COG4195	phage-related replication protein
OB04_RS09370	COG1764	response to oxidative stress
OB04_RS09375	COG2076	Multidrug Resistance protein
OB04_RS09380	COG2076	Multidrug Resistance protein
OB04_RS09395	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OB04_RS09400	COG1923	regulation of RNA biosynthetic process
OB04_RS09415	COG1780	Probably involved in ribonucleotide reductase function
OB04_RS09420	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OB04_RS09425	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OB04_RS09430	COG4112	unkown
OB04_RS09435	COG0860	N-Acetylmuramoyl-L-alanine amidase
OB04_RS09440	COG0464	growth
OB04_RS09450	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OB04_RS09455	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
OB04_RS09460	COG0789	Transcriptional regulator
OB04_RS09465	COG0174	glutamine synthetase
OB04_RS09500	COG0463	Glycosyl transferase, family 2
OB04_RS09515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OB04_RS09530	COG3655	Transcriptional regulator
OB04_RS09545	COG0135	phosphoribosylanthranilate isomerase activity
OB04_RS09555	COG2211	Major facilitator Superfamily
OB04_RS09560	COG3507	Belongs to the glycosyl hydrolase 43 family
OB04_RS09565	COG1940	carbohydrate kinase activity
OB04_RS09570	COG2115	Belongs to the xylose isomerase family
OB04_RS09575	COG1070	Carbohydrate kinase
OB04_RS09580	COG1525	nuclease
OB04_RS09585	COG2814	Major facilitator Superfamily
OB04_RS09590	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OB04_RS09600	COG0756	dUTP diphosphatase activity
OB04_RS09610	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OB04_RS09645	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OB04_RS09660	COG3832	glyoxalase III activity
OB04_RS09675	COG0697	spore germination
OB04_RS09680	COG0531	amino acid
OB04_RS09710	COG4195	phage-related replication protein
OB04_RS09720	COG0346	lactoylglutathione lyase activity
OB04_RS09730	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OB04_RS09735	COG1388	LysM domain
OB04_RS09740	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OB04_RS09745	COG4224	UPF0291 protein
OB04_RS09750	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OB04_RS09760	COG3763	UPF0154 protein
OB04_RS09770	COG0785	Cytochrome C biogenesis protein
OB04_RS09775	COG2201	protein-glutamate methylesterase activity
OB04_RS09780	COG4846	Membrane protein involved in cytochrome C biogenesis
OB04_RS09790	COG0071	Belongs to the small heat shock protein (HSP20) family
OB04_RS09805	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OB04_RS09810	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OB04_RS09830	COG0824	Thioesterase
OB04_RS09840	COG4841	protein insertion into membrane
OB04_RS09845	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
OB04_RS09850	COG1832	CoA-binding protein
OB04_RS09855	COG0187	DNA topoisomerase II activity
OB04_RS09860	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OB04_RS09875	COG1115	amino acid carrier protein
OB04_RS09880	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
OB04_RS09890	COG5520	Belongs to the glycosyl hydrolase 30 family
OB04_RS09895	COG3507	Belongs to the glycosyl hydrolase 43 family
OB04_RS09900	COG2246	polysaccharide biosynthetic process
OB04_RS09905	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OB04_RS09910	COG0586	Pfam SNARE associated Golgi protein
OB04_RS09915	COG2404	hydrolase activity, acting on ester bonds
OB04_RS09920	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OB04_RS09925	COG1024	Enoyl-CoA hydratase
OB04_RS09930	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OB04_RS09935	COG0511	ligase activity, forming carbon-carbon bonds
OB04_RS09940	COG0439	Biotin carboxylase
OB04_RS09945	COG0318	PFAM AMP-dependent synthetase and ligase
OB04_RS09950	COG1960	acyl-CoA dehydrogenase activity
OB04_RS09965	COG1649	PFAM Uncharacterised BCR, COG1649
OB04_RS09975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OB04_RS09975	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
OB04_RS09980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OB04_RS09985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OB04_RS09990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OB04_RS09995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OB04_RS10000	COG2027	D-alanyl-D-alanine carboxypeptidase
OB04_RS10005	COG2017	converts alpha-aldose to the beta-anomer
OB04_RS10010	COG0534	Mate efflux family protein
OB04_RS10025	COG0582	viral genome integration into host DNA
OB04_RS10030	COG0166	Belongs to the GPI family
OB04_RS10035	COG0405	Gamma-glutamyltransferase
OB04_RS10040	COG0583	DNA-binding transcription factor activity
OB04_RS10045	COG0604	alcohol dehydrogenase
OB04_RS10050	COG0493	'glutamate synthase
OB04_RS10055	COG0067	glutamate synthase
OB04_RS10055	COG0069	glutamate synthase activity
OB04_RS10055	COG0070	glutamate synthase
OB04_RS10060	COG0583	DNA-binding transcription factor activity
OB04_RS10065	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OB04_RS10070	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OB04_RS10080	COG0300	oxidoreductase activity
OB04_RS10085	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
OB04_RS10095	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OB04_RS10100	COG2814	Major facilitator Superfamily
OB04_RS10105	COG1070	Carbohydrate kinase
OB04_RS10110	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OB04_RS10115	COG0243	molybdopterin cofactor binding
OB04_RS10140	COG0840	transmembrane signaling receptor activity
OB04_RS10140	COG5278	phosphoserine phosphatase activity
OB04_RS10145	COG2368	4-hydroxyphenylacetate
OB04_RS10150	COG4305	rare lipoprotein A
OB04_RS10155	COG3619	membrane
OB04_RS10160	COG3866	Pectate lyase
OB04_RS10165	COG2135	peptidase activity
OB04_RS10175	COG2140	Oxalate decarboxylase
OB04_RS10185	COG0456	acetyltransferase
OB04_RS10205	COG2720	vancomycin resistance protein
OB04_RS10215	COG3655	Transcriptional regulator
OB04_RS10220	COG3739	integral membrane protein
OB04_RS10225	COG0583	DNA-binding transcription factor activity
OB04_RS10230	COG0697	spore germination
OB04_RS10240	COG0693	protein deglycase activity
OB04_RS10245	COG2367	Beta-lactamase
OB04_RS10265	COG3848	Pyruvate phosphate dikinase
OB04_RS10265	COG0574	Belongs to the PEP-utilizing enzyme family
OB04_RS10270	COG0726	polysaccharide deacetylase
OB04_RS10280	COG2314	TM2 domain
OB04_RS10285	COG1396	sequence-specific DNA binding
OB04_RS10325	COG2723	6-phospho-beta-galactosidase activity
OB04_RS10340	COG0395	ABC-type sugar transport system, permease component
OB04_RS10345	COG1175	transmembrane transport
OB04_RS10355	COG1940	carbohydrate kinase activity
OB04_RS10365	COG5444	nuclease activity
OB04_RS10370	COG4282	regulation of fungal-type cell wall biogenesis
OB04_RS10375	COG1231	oxidoreductase activity
OB04_RS10380	COG5434	Belongs to the glycosyl hydrolase 28 family
OB04_RS10385	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OB04_RS10390	COG0662	Cupin 2, conserved barrel domain protein
OB04_RS10390	COG2207	Transcriptional regulator
OB04_RS10395	COG0456	acetyltransferase
OB04_RS10400	COG1309	transcriptional regulator
OB04_RS10405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OB04_RS10410	COG3708	Transcriptional regulator
OB04_RS10415	COG2378	regulation of single-species biofilm formation
OB04_RS10425	COG0640	Transcriptional regulator
OB04_RS10430	COG0741	lytic transglycosylase activity
OB04_RS10435	COG2322	membrane
OB04_RS10450	COG1619	proteins homologs of microcin C7 resistance protein MccF
OB04_RS10455	COG3239	Fatty acid desaturase
OB04_RS10460	COG4585	Histidine kinase
OB04_RS10465	COG2197	response regulator
OB04_RS10470	COG1388	LysM domain
OB04_RS10470	COG3584	3D domain protein
OB04_RS10475	COG0514	ATP-dependent DNA helicase (RecQ)
OB04_RS10485	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OB04_RS10490	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OB04_RS10505	COG0071	Belongs to the small heat shock protein (HSP20) family
OB04_RS10530	COG1012	belongs to the aldehyde dehydrogenase family
OB04_RS10535	COG1657	PFAM Prenyltransferase squalene oxidase
OB04_RS10540	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OB04_RS10545	COG0733	neurotransmitter:sodium symporter activity
OB04_RS10550	COG0385	Bile acid
OB04_RS10555	COG0508	dehydrogenase complex catalyzes the overall conversion of
OB04_RS10560	COG0567	Dehydrogenase, E1 component
OB04_RS10565	COG4548	von Willebrand factor, type A
OB04_RS10570	COG0714	Associated with various cellular activities
OB04_RS10575	COG2032	superoxide dismutase activity
OB04_RS10580	COG0791	NLP P60 protein
OB04_RS10580	COG1388	LysM domain
OB04_RS10585	COG1819	glycosyl
OB04_RS10590	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OB04_RS10595	COG0534	Mate efflux family protein
OB04_RS10600	COG1366	Belongs to the anti-sigma-factor antagonist family
OB04_RS10605	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OB04_RS10610	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OB04_RS10620	COG2962	Rard protein
OB04_RS10635	COG2610	gluconate transmembrane transporter activity
OB04_RS10640	COG1942	4-Oxalocrotonate Tautomerase
OB04_RS10645	COG1733	regulation of RNA biosynthetic process
OB04_RS10650	COG0778	Nitroreductase
OB04_RS10655	COG0400	carboxylic ester hydrolase activity
OB04_RS10660	COG0346	lactoylglutathione lyase activity
OB04_RS10670	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OB04_RS10675	COG3409	Peptidoglycan-binding domain 1 protein
OB04_RS10675	COG0793	Belongs to the peptidase S41A family
OB04_RS10680	COG2226	methyltransferase
OB04_RS10690	COG1876	peptidase activity
OB04_RS10695	COG0813	purine-nucleoside phosphorylase activity
OB04_RS10710	COG0671	phosphoesterase, PA-phosphatase related
OB04_RS10735	COG4479	Belongs to the UPF0346 family
OB04_RS10745	COG1509	lysine 2,3-aminomutase activity
OB04_RS10750	COG0456	acetyltransferase
OB04_RS10755	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OB04_RS10760	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OB04_RS10765	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OB04_RS10770	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OB04_RS10785	COG0456	acetyltransferase
OB04_RS10790	COG0463	Glycosyl transferase, family 2
OB04_RS10805	COG4641	Protein conserved in bacteria
OB04_RS10810	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
OB04_RS10815	COG1086	Polysaccharide biosynthesis protein
OB04_RS10820	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OB04_RS10825	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OB04_RS10830	COG1846	Transcriptional regulator
OB04_RS10835	COG0534	Mate efflux family protein
OB04_RS10845	COG4698	Protein conserved in bacteria
OB04_RS10850	COG2755	lipolytic protein G-D-S-L family
OB04_RS10855	COG1999	signal sequence binding
OB04_RS10870	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OB04_RS10875	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
OB04_RS10880	COG1272	protein, Hemolysin III
OB04_RS10885	COG0204	Acyl-transferase
OB04_RS10890	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OB04_RS10895	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OB04_RS10900	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
OB04_RS10910	COG2521	methyltransferase
OB04_RS10910	COG2136	Putative SAM-dependent methyltransferase
OB04_RS10920	COG0129	dihydroxy-acid dehydratase activity
OB04_RS10925	COG1413	lyase activity
OB04_RS10930	COG1418	mRNA catabolic process
OB04_RS10935	COG0386	Belongs to the glutathione peroxidase family
OB04_RS10940	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
OB04_RS10945	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OB04_RS10950	COG1278	Cold shock
OB04_RS10970	COG0328	RNA-DNA hybrid ribonuclease activity
OB04_RS10975	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
OB04_RS10980	COG0328	RNA-DNA hybrid ribonuclease activity
OB04_RS10990	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OB04_RS11010	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
OB04_RS11015	COG1755	Isoprenylcysteine carboxyl methyltransferase
OB04_RS11020	COG3424	synthase
OB04_RS11025	COG2233	PERMEase
OB04_RS11030	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OB04_RS11035	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
OB04_RS11045	COG0800	Aldolase
OB04_RS11050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OB04_RS11055	COG1609	Transcriptional regulator
OB04_RS11060	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
OB04_RS11065	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_RS11070	COG1199	ATP-dependent helicase activity
OB04_RS11080	COG0116	Belongs to the methyltransferase superfamily
OB04_RS11090	COG4474	Belongs to the UPF0398 family
OB04_RS11100	COG3359	exonuclease
OB04_RS11105	COG1111	helicase
OB04_RS11105	COG1205	dead DEAH box helicase
OB04_RS11110	COG2190	(PTS) system
OB04_RS11115	COG0071	Belongs to the small heat shock protein (HSP20) family
OB04_RS11150	COG3331	DNA recombination
OB04_RS11155	COG4499	WXG100 protein secretion system (Wss), protein YukC
OB04_RS11155	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OB04_RS11165	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OB04_RS11170	COG3935	DnaD domain protein
OB04_RS11175	COG0017	Asparaginyl-tRNA synthetase
OB04_RS11180	COG0436	Aminotransferase
OB04_RS11185	COG5353	protein conserved in bacteria
OB04_RS11195	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OB04_RS11195	COG1199	ATP-dependent helicase activity
OB04_RS11200	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
OB04_RS11205	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OB04_RS11210	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
OB04_RS11215	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
OB04_RS11215	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
OB04_RS11220	COG0617	tRNA 3'-terminal CCA addition
OB04_RS11225	COG0438	transferase activity, transferring glycosyl groups
OB04_RS11230	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OB04_RS11235	COG1803	Methylglyoxal synthase
OB04_RS11240	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
OB04_RS11245	COG1694	Mazg nucleotide pyrophosphohydrolase
OB04_RS11250	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OB04_RS11260	COG4347	Protein of unknown function (DUF1405)
OB04_RS11265	COG2010	Cytochrome c
OB04_RS11265	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
OB04_RS11270	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
OB04_RS11275	COG0723	plastoquinol--plastocyanin reductase activity
OB04_RS11285	COG5582	Belongs to the UPF0302 family
OB04_RS11290	COG0457	Tetratricopeptide repeat
OB04_RS11295	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OB04_RS11300	COG0287	Prephenate dehydrogenase
OB04_RS11310	COG0159	tryptophan synthase activity
OB04_RS11315	COG0133	tryptophan synthase activity
OB04_RS11320	COG0135	phosphoribosylanthranilate isomerase activity
OB04_RS11330	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OB04_RS11335	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OB04_RS11340	COG4401	Chorismate mutase type I
OB04_RS11345	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OB04_RS11350	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OB04_RS11355	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
OB04_RS11365	COG0105	UTP biosynthetic process
OB04_RS11370	COG0142	geranyltranstransferase activity
OB04_RS11375	COG2226	methyltransferase
OB04_RS11380	COG0142	geranyltranstransferase activity
OB04_RS11390	COG0302	gtp cyclohydrolase
OB04_RS11395	COG0776	regulation of translation
OB04_RS11400	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
OB04_RS11415	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
OB04_RS11420	COG1160	GTP binding
OB04_RS11445	COG1304	FMN binding
OB04_RS11450	COG0539	negative regulation of cytoplasmic translation
OB04_RS11455	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
OB04_RS11465	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
OB04_RS11470	COG2959	enzyme of heme biosynthesis
OB04_RS11475	COG3409	Peptidoglycan-binding domain 1 protein
OB04_RS11475	COG3773	Cell wall hydrolase
OB04_RS11480	COG2339	peptidase activity
OB04_RS11485	COG0492	ferredoxin-NADP+ reductase activity
OB04_RS11490	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OB04_RS11495	COG4862	establishment of competence for transformation
OB04_RS11500	COG1408	metallophosphoesterase
OB04_RS11510	COG1388	LysM domain
OB04_RS11515	COG1266	CAAX protease self-immunity
OB04_RS11520	COG0514	ATP-dependent DNA helicase (RecQ)
OB04_RS11525	COG4955	Helix-turn-helix domain
OB04_RS11530	COG1141	Ferredoxin
OB04_RS11535	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
OB04_RS11545	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OB04_RS11550	COG0710	3-dehydroquinate dehydratase activity
OB04_RS11560	COG1595	DNA-templated transcription, initiation
OB04_RS11565	COG5002	protein histidine kinase activity
OB04_RS11570	COG0745	RESPONSE REGULATOR receiver
OB04_RS11575	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OB04_RS11580	COG1333	cytochrome c biogenesis protein
OB04_RS11585	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OB04_RS11590	COG1187	pseudouridine synthase activity
OB04_RS11595	COG0700	Nucleoside recognition
OB04_RS11600	COG2715	membrane protein required for spore maturation
OB04_RS11605	COG1686	Belongs to the peptidase S11 family
OB04_RS11615	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OB04_RS11620	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OB04_RS11625	COG1547	Domain of unknown function (DUF309)
OB04_RS11630	COG0456	acetyltransferase
OB04_RS11635	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
OB04_RS11640	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OB04_RS11640	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OB04_RS11645	COG0307	riboflavin synthase, alpha
OB04_RS11650	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OB04_RS11650	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OB04_RS11660	COG0681	Belongs to the peptidase S26 family
OB04_RS11665	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
OB04_RS11685	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OB04_RS11690	COG4086	secreted protein
OB04_RS11695	COG0019	diaminopimelate decarboxylase activity
OB04_RS11700	COG0697	spore germination
OB04_RS11715	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OB04_RS11735	COG1191	sigma factor activity
OB04_RS11740	COG2172	sigma factor antagonist activity
OB04_RS11745	COG1366	Belongs to the anti-sigma-factor antagonist family
OB04_RS11750	COG1686	Belongs to the peptidase S11 family
OB04_RS11755	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
OB04_RS11760	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
OB04_RS11765	COG4974	Belongs to the 'phage' integrase family
OB04_RS11775	COG0735	belongs to the Fur family
OB04_RS11780	COG1300	Membrane
OB04_RS11790	COG0281	malic enzyme
OB04_RS11795	COG1757	Na H antiporter
OB04_RS11800	COG1027	Aspartate ammonia-lyase
OB04_RS11805	COG0252	asparaginase activity
OB04_RS11810	COG1396	sequence-specific DNA binding
OB04_RS11815	COG1379	DNA repair
OB04_RS11820	COG0494	nUDIX hydrolase
OB04_RS11830	COG0667	Aldo Keto reductase
OB04_RS11850	COG4918	Iron-sulphur cluster biosynthesis
OB04_RS11855	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OB04_RS11855	COG0456	acetyltransferase
OB04_RS11860	COG2329	Antibiotic biosynthesis monooxygenase
OB04_RS11865	COG0456	acetyltransferase
OB04_RS11875	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OB04_RS11900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OB04_RS11905	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OB04_RS11925	COG0492	ferredoxin-NADP+ reductase activity
OB04_RS11930	COG3118	belongs to the thioredoxin family
OB04_RS11940	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OB04_RS11950	COG0509	glycine decarboxylation via glycine cleavage system
OB04_RS11960	COG1309	transcriptional regulator
OB04_RS11965	COG1609	Transcriptional regulator
OB04_RS11975	COG1175	transmembrane transport
OB04_RS11980	COG0395	ABC-type sugar transport system, permease component
OB04_RS11990	COG1621	beta-fructofuranosidase activity
OB04_RS12035	COG0210	DNA helicase
OB04_RS12045	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OB04_RS12075	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OB04_RS12085	COG2211	Major facilitator Superfamily
OB04_RS12095	COG0346	lactoylglutathione lyase activity
OB04_RS12100	COG1072	(Pantothenic acid kinase))
OB04_RS12105	COG3048	D-serine ammonia-lyase activity
OB04_RS12110	COG0300	oxidoreductase activity
OB04_RS12115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OB04_RS12120	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OB04_RS12125	COG4187	Peptidase family M20/M25/M40
OB04_RS12130	COG1902	pentaerythritol trinitrate reductase activity
OB04_RS12135	COG0596	Alpha beta hydrolase
OB04_RS12145	COG1234	tRNA 3'-trailer cleavage
OB04_RS12150	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OB04_RS12155	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OB04_RS12160	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OB04_RS12170	COG0706	membrane insertase activity
OB04_RS12175	COG3361	conserved protein (COG2071)
OB04_RS12180	COG2195	Cleaves the N-terminal amino acid of tripeptides
OB04_RS12185	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OB04_RS12190	COG0346	lactoylglutathione lyase activity
OB04_RS12200	COG1376	ErfK ybiS ycfS ynhG family protein
OB04_RS12205	COG4129	membrane
OB04_RS12210	COG1126	abc transporter atp-binding protein
OB04_RS12215	COG0765	amino acid transport
OB04_RS12220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OB04_RS12230	COG1597	lipid kinase activity
OB04_RS12235	COG2814	Major facilitator Superfamily
OB04_RS12240	COG0789	Transcriptional regulator
OB04_RS12240	COG4978	Transcriptional regulator
OB04_RS12245	COG0508	dehydrogenase complex catalyzes the overall conversion of
OB04_RS12250	COG0022	dehydrogenase e1 component
OB04_RS12255	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OB04_RS12260	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OB04_RS12265	COG3426	butyrate kinase activity
OB04_RS12270	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OB04_RS12275	COG0280	phosphate acetyltransferase
OB04_RS12280	COG3290	protein histidine kinase activity
OB04_RS12280	COG3829	transcription factor binding
OB04_RS12290	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
OB04_RS12295	COG2079	MmgE PrpD family protein
OB04_RS12300	COG0372	Belongs to the citrate synthase family
OB04_RS12305	COG1960	acyl-CoA dehydrogenase activity
OB04_RS12310	COG1250	3-hydroxyacyl-CoA dehydrogenase
OB04_RS12315	COG0183	Belongs to the thiolase family
OB04_RS12320	COG0584	glycerophosphoryl diester phosphodiesterase
OB04_RS12325	COG0860	N-Acetylmuramoyl-L-alanine amidase
OB04_RS12340	COG1902	pentaerythritol trinitrate reductase activity
OB04_RS12350	COG0745	RESPONSE REGULATOR receiver
OB04_RS12360	COG0750	zinc metalloprotease
OB04_RS12365	COG0497	DNA recombination
OB04_RS12370	COG1438	arginine binding
OB04_RS12375	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
OB04_RS12380	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OB04_RS12385	COG0142	geranyltranstransferase activity
OB04_RS12390	COG1722	exodeoxyribonuclease VII activity
OB04_RS12395	COG1570	exodeoxyribonuclease VII activity
OB04_RS12400	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OB04_RS12405	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OB04_RS12410	COG1302	Protein conserved in bacteria
OB04_RS12415	COG0439	Biotin carboxylase
OB04_RS12420	COG0511	ligase activity, forming carbon-carbon bonds
OB04_RS12460	COG3854	ATPases associated with a variety of cellular activities
OB04_RS12470	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OB04_RS12475	COG0006	proline dipeptidase activity
OB04_RS12480	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
OB04_RS12490	COG3872	metal-dependent enzyme
OB04_RS12500	COG1752	Esterase of the alpha-beta hydrolase superfamily
OB04_RS12505	COG1321	iron dependent repressor
OB04_RS12510	COG0095	Lipoate-protein ligase
OB04_RS12515	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OB04_RS12520	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OB04_RS12525	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OB04_RS12530	COG0404	The glycine cleavage system catalyzes the degradation of glycine
OB04_RS12535	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OB04_RS12550	COG1396	sequence-specific DNA binding
OB04_RS12560	COG0681	Belongs to the peptidase S26 family
OB04_RS12585	COG4940	Competence protein ComGF
OB04_RS12595	COG4970	Tfp pilus assembly protein FimT
OB04_RS12600	COG4537	Required for transformation and DNA binding
OB04_RS12605	COG1459	type II secretion system
OB04_RS12610	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OB04_RS12625	COG0598	Magnesium transport protein CorA
OB04_RS12630	COG1253	flavin adenine dinucleotide binding
OB04_RS12635	COG1366	Belongs to the anti-sigma-factor antagonist family
OB04_RS12645	COG1393	Belongs to the ArsC family
OB04_RS12655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OB04_RS12665	COG0011	TIGRFAM Protein of
OB04_RS12675	COG2866	Carboxypeptidase
OB04_RS12680	COG1368	sulfuric ester hydrolase activity
OB04_RS12685	COG1940	carbohydrate kinase activity
OB04_RS12690	COG4483	Protein conserved in bacteria
OB04_RS12695	COG0705	Rhomboid family
OB04_RS12695	COG0457	Tetratricopeptide repeat
OB04_RS12705	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OB04_RS12715	COG0438	transferase activity, transferring glycosyl groups
OB04_RS12730	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OB04_RS12735	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OB04_RS12740	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OB04_RS12745	COG0581	inorganic phosphate transmembrane transporter activity
OB04_RS12750	COG0573	inorganic phosphate transmembrane transporter activity
OB04_RS12755	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OB04_RS12760	COG0768	penicillin binding
OB04_RS12765	COG0477	Major facilitator Superfamily
OB04_RS12770	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OB04_RS12775	COG2839	Protein conserved in bacteria
OB04_RS12780	COG5521	maltodextrose utilization protein MalA
OB04_RS12785	COG1388	LysM domain
OB04_RS12790	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OB04_RS12795	COG4709	membrane
OB04_RS12800	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
OB04_RS12805	COG0735	belongs to the Fur family
OB04_RS12810	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OB04_RS12820	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
OB04_RS12825	COG0513	Belongs to the DEAD box helicase family
OB04_RS12835	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OB04_RS12840	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OB04_RS12845	COG2384	SAM-dependent methyltransferase
OB04_RS12850	COG2010	Cytochrome c
OB04_RS12855	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OB04_RS12860	COG0358	DNA primase activity
OB04_RS12865	COG1671	Belongs to the UPF0178 family
OB04_RS12870	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
OB04_RS12875	COG0517	IMP dehydrogenase activity
OB04_RS12880	COG0751	glycine-tRNA ligase activity
OB04_RS12885	COG0752	glycyl-tRNA synthetase alpha subunit
OB04_RS12890	COG1381	Involved in DNA repair and RecF pathway recombination
OB04_RS12900	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OB04_RS12905	COG0295	cytidine deaminase activity
OB04_RS12910	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
OB04_RS12915	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OB04_RS12920	COG1480	7TM receptor with intracellular HD hydrolase
OB04_RS12930	COG1702	phosphate starvation-inducible protein PhoH
OB04_RS12935	COG0561	phosphatase activity
OB04_RS12950	COG4864	UPF0365 protein
OB04_RS12955	COG1030	water channel activity
OB04_RS12960	COG1610	YqeY-like protein
OB04_RS12970	COG1283	sodium-dependent phosphate transmembrane transporter activity
OB04_RS12975	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OB04_RS12980	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OB04_RS12985	COG2264	protein methyltransferase activity
OB04_RS12990	COG0484	heat shock protein binding
OB04_RS12995	COG0443	Heat shock 70 kDa protein
OB04_RS13000	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OB04_RS13005	COG1420	regulation of RNA biosynthetic process
OB04_RS13010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OB04_RS13015	COG0481	GTPase activity
OB04_RS13025	COG0860	N-Acetylmuramoyl-L-alanine amidase
OB04_RS13030	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
OB04_RS13035	COG0268	Binds directly to 16S ribosomal RNA
OB04_RS13040	COG1466	dna polymerase III delta subunit
OB04_RS13050	COG0658	competence protein
OB04_RS13050	COG2333	competence protein COMEC
OB04_RS13055	COG2131	deaminase
OB04_RS13060	COG1555	photosystem II stabilization
OB04_RS13060	COG1596	polysaccharide export
OB04_RS13065	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OB04_RS13070	COG2226	methyltransferase
OB04_RS13075	COG0799	negative regulation of ribosome biogenesis
OB04_RS13080	COG1713	HD superfamily hydrolase involved in NAD metabolism
OB04_RS13085	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OB04_RS13090	COG1534	Rna-binding protein
OB04_RS13095	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OB04_RS13100	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OB04_RS13105	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
OB04_RS13120	COG2755	lipolytic protein G-D-S-L family
OB04_RS13130	COG3409	Peptidoglycan-binding domain 1 protein
OB04_RS13130	COG5632	N-Acetylmuramoyl-L-alanine amidase
OB04_RS13135	COG0398	Pfam SNARE associated Golgi protein
OB04_RS13140	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
OB04_RS13150	COG3209	COG3209 Rhs family protein
OB04_RS13170	COG2249	NAD(P)H dehydrogenase (quinone) activity
OB04_RS13180	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OB04_RS13190	COG2315	Protein conserved in bacteria
OB04_RS13195	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OB04_RS13215	COG2272	Belongs to the type-B carboxylesterase lipase family
OB04_RS13220	COG0457	Tetratricopeptide repeat
OB04_RS13225	COG5444	nuclease activity
OB04_RS13265	COG1783	phage Terminase large subunit
OB04_RS13275	COG3677	Transposase
OB04_RS13300	COG0563	adenylate kinase activity
OB04_RS13305	COG2856	Zn peptidase
OB04_RS13325	COG4124	Belongs to the glycosyl hydrolase 26 family
OB04_RS13330	COG0730	response to heat
OB04_RS13335	COG0425	Belongs to the sulfur carrier protein TusA family
OB04_RS13340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OB04_RS13340	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OB04_RS13350	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OB04_RS13350	COG0425	Belongs to the sulfur carrier protein TusA family
OB04_RS13355	COG2210	Belongs to the sulfur carrier protein TusA family
OB04_RS13360	COG1937	Protein conserved in bacteria
OB04_RS13365	COG0662	Cupin 2, conserved barrel domain protein
OB04_RS13380	COG0789	Transcriptional regulator
OB04_RS13380	COG4978	Transcriptional regulator
OB04_RS13385	COG2814	Major facilitator Superfamily
OB04_RS13390	COG0456	acetyltransferase
OB04_RS13395	COG1253	flavin adenine dinucleotide binding
OB04_RS13405	COG0697	spore germination
OB04_RS13410	COG0583	DNA-binding transcription factor activity
OB04_RS13415	COG2072	flavoprotein involved in K transport
OB04_RS13420	COG1230	cation diffusion facilitator family transporter
OB04_RS13425	COG1942	4-Oxalocrotonate Tautomerase
OB04_RS13430	COG0583	DNA-binding transcription factor activity
OB04_RS13440	COG1114	Component of the transport system for branched-chain amino acids
OB04_RS13445	COG1687	branched-chain amino acid
OB04_RS13450	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
OB04_RS13455	COG1522	sequence-specific DNA binding
OB04_RS13460	COG2732	(Barnase) inhibitor
OB04_RS13465	COG2124	cytochrome p450
OB04_RS13475	COG1335	isochorismatase
OB04_RS13485	COG2318	DinB family
OB04_RS13495	COG2070	2-Nitropropane dioxygenase
OB04_RS13500	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OB04_RS13515	COG3443	Belongs to the bacterial solute-binding protein 9 family
OB04_RS13520	COG1595	DNA-templated transcription, initiation
OB04_RS13525	COG0667	Aldo Keto reductase
OB04_RS13530	COG2851	Citrate transporter
OB04_RS13535	COG0583	DNA-binding transcription factor activity
OB04_RS13540	COG2828	Protein conserved in bacteria
OB04_RS13545	COG3409	Peptidoglycan-binding domain 1 protein
OB04_RS13550	COG5566	PFAM Mor transcription activator
OB04_RS13555	COG0596	Alpha beta hydrolase
OB04_RS13560	COG4991	sh3 domain protein
OB04_RS13565	COG4991	sh3 domain protein
OB04_RS13570	COG0346	lactoylglutathione lyase activity
OB04_RS13580	COG5577	PFAM Coat F domain
OB04_RS13585	COG1063	alcohol dehydrogenase
OB04_RS13595	COG5577	PFAM Coat F domain
OB04_RS13600	COG0789	Transcriptional regulator
OB04_RS13610	COG1064	alcohol dehydrogenase
OB04_RS13615	COG0693	protein deglycase activity
OB04_RS13620	COG1621	beta-fructofuranosidase activity
OB04_RS13625	COG3716	PTS system mannose fructose sorbose family IID component
OB04_RS13630	COG3715	PTS system
OB04_RS13635	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OB04_RS13640	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
OB04_RS13645	COG3933	PFAM sigma-54 factor interaction domain-containing protein
OB04_RS13645	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
OB04_RS13650	COG1113	amino acid transport
OB04_RS13655	COG1280	lysine exporter protein (LysE YggA)
OB04_RS13660	COG1378	Sugar-specific transcriptional regulator TrmB
OB04_RS13665	COG1595	DNA-templated transcription, initiation
OB04_RS13675	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
OB04_RS13675	COG2755	lipolytic protein G-D-S-L family
OB04_RS13685	COG2124	cytochrome p450
OB04_RS13685	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OB04_RS13690	COG1309	transcriptional regulator
OB04_RS13695	COG2226	methyltransferase
OB04_RS13710	COG2116	formate transmembrane transporter activity
OB04_RS13715	COG5609	conserved protein (DUF2294)
OB04_RS13720	COG3383	formate dehydrogenase (NAD+) activity
OB04_RS13725	COG2427	Protein of unknown function (DUF1641)
OB04_RS13735	COG0626	cystathionine gamma-synthase activity
OB04_RS13740	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OB04_RS13745	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OB04_RS13750	COG2226	methyltransferase
OB04_RS13765	COG0768	penicillin binding
OB04_RS13770	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OB04_RS13775	COG0572	uridine kinase
OB04_RS13780	COG0826	peptidase U32
OB04_RS13785	COG0826	peptidase U32
OB04_RS13790	COG4122	O-methyltransferase activity
OB04_RS13795	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OB04_RS13800	COG3906	Belongs to the UPF0473 family
OB04_RS13805	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OB04_RS13810	COG4472	Bacterial protein of unknown function (DUF965)
OB04_RS13815	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OB04_RS13820	COG0628	permease
OB04_RS13825	COG1126	abc transporter atp-binding protein
OB04_RS13830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OB04_RS13835	COG0765	amino acid transport
OB04_RS13840	COG0765	amino acid transport
OB04_RS13855	COG3881	PFAM PRC-barrel domain
OB04_RS13860	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OB04_RS13865	COG0457	Tetratricopeptide repeat
OB04_RS13870	COG0482	sulfurtransferase activity
OB04_RS13875	COG1104	cysteine desulfurase activity
OB04_RS13880	COG1959	2 iron, 2 sulfur cluster binding
OB04_RS13885	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OB04_RS13890	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OB04_RS13900	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OB04_RS13905	COG0124	histidyl-tRNA synthetase
OB04_RS13915	COG4991	sh3 domain protein
OB04_RS13915	COG3103	Sh3 type 3 domain protein
OB04_RS13915	COG0860	N-Acetylmuramoyl-L-alanine amidase
OB04_RS13920	COG1490	D-aminoacyl-tRNA deacylase activity
OB04_RS13925	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OB04_RS13930	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OB04_RS13935	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
OB04_RS13935	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OB04_RS13940	COG5416	Lipopolysaccharide assembly protein A domain
OB04_RS13945	COG0490	domain, Protein
OB04_RS13950	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OB04_RS13950	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OB04_RS13960	COG2244	polysaccharide biosynthetic process
OB04_RS13965	COG2323	membrane
OB04_RS13975	COG1862	Preprotein translocase
OB04_RS13980	COG0343	queuine tRNA-ribosyltransferase activity
OB04_RS13985	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OB04_RS13995	COG2255	four-way junction helicase activity
OB04_RS14000	COG0632	four-way junction helicase activity
OB04_RS14010	COG2814	Major facilitator Superfamily
OB04_RS14015	COG0673	inositol 2-dehydrogenase activity
OB04_RS14020	COG2112	serine threonine protein kinase
OB04_RS14040	COG1115	amino acid carrier protein
OB04_RS14045	COG0217	transcriptional regulatory protein
OB04_RS14055	COG1388	LysM domain
OB04_RS14060	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OB04_RS14065	COG0157	Belongs to the NadC ModD family
OB04_RS14070	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
OB04_RS14075	COG1104	cysteine desulfurase activity
OB04_RS14080	COG1827	regulation of RNA biosynthetic process
OB04_RS14085	COG0077	Prephenate dehydratase
OB04_RS14090	COG4492	Belongs to the UPF0735 family
OB04_RS14095	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OB04_RS14100	COG3290	protein histidine kinase activity
OB04_RS14110	COG0211	Belongs to the bacterial ribosomal protein bL27 family
OB04_RS14115	COG2868	ribosomal protein
OB04_RS14120	COG0261	This protein binds to 23S rRNA in the presence of protein L20
OB04_RS14125	COG1994	Peptidase M50
OB04_RS14130	COG0739	heme binding
OB04_RS14135	COG2894	cell division
OB04_RS14140	COG0850	regulation of cytokinetic process
OB04_RS14145	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
OB04_RS14155	COG1077	Cell shape determining protein MreB Mrl
OB04_RS14160	COG2003	Belongs to the UPF0758 family
OB04_RS14165	COG0424	maF-like protein
OB04_RS14175	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
OB04_RS14180	COG0285	dihydrofolate synthase activity
OB04_RS14185	COG0525	valine-tRNA ligase activity
OB04_RS14195	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OB04_RS14200	COG1388	LysM domain
OB04_RS14205	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OB04_RS14210	COG0113	porphobilinogen synthase activity
OB04_RS14215	COG1587	Uroporphyrinogen-III synthase
OB04_RS14220	COG0181	hydroxymethylbilane synthase activity
OB04_RS14225	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OB04_RS14230	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
OB04_RS14240	COG0218	Necessary for normal cell division and for the maintenance of normal septation
OB04_RS14245	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
OB04_RS14250	COG0470	DNA polymerase III
OB04_RS14250	COG1067	ATP-dependent peptidase activity
OB04_RS14255	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OB04_RS14260	COG0544	peptidyl-prolyl cis-trans isomerase activity
OB04_RS14265	COG1477	protein flavinylation
OB04_RS14265	COG0457	Tetratricopeptide repeat
OB04_RS14270	COG0066	3-isopropylmalate dehydratase activity
OB04_RS14275	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OB04_RS14280	COG0473	3-isopropylmalate dehydrogenase activity
OB04_RS14285	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OB04_RS14290	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OB04_RS14295	COG0440	acetolactate synthase activity
OB04_RS14300	COG0028	Belongs to the TPP enzyme family
OB04_RS14310	COG0454	-acetyltransferase
OB04_RS14325	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
OB04_RS14335	COG0622	Phosphoesterase
OB04_RS14340	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OB04_RS14345	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OB04_RS14350	COG5401	PFAM Sporulation and spore germination
OB04_RS14355	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OB04_RS14360	COG1846	Transcriptional regulator
OB04_RS14365	COG2197	response regulator
OB04_RS14370	COG0824	Thioesterase
OB04_RS14375	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OB04_RS14380	COG1053	succinate dehydrogenase
OB04_RS14385	COG2009	succinate dehydrogenase
OB04_RS14395	COG1719	4-vinyl reductase, 4VR
OB04_RS14400	COG0527	aspartate kinase activity
OB04_RS14405	COG0322	excinuclease ABC activity
OB04_RS14410	COG3118	belongs to the thioredoxin family
OB04_RS14415	COG3534	alpha-L-arabinofuranosidase
OB04_RS14420	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
OB04_RS14425	COG2086	electron transfer activity
OB04_RS14430	COG1024	Enoyl-CoA hydratase
OB04_RS14435	COG1309	transcriptional regulator
OB04_RS14440	COG0318	PFAM AMP-dependent synthetase and ligase
OB04_RS14445	COG3766	membrane
OB04_RS14450	COG1193	negative regulation of DNA recombination
OB04_RS14455	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
OB04_RS14455	COG1796	DNA polymerase
OB04_RS14460	COG1286	toxin biosynthetic process
OB04_RS14465	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
OB04_RS14470	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OB04_RS14475	COG0072	phenylalanine-tRNA ligase activity
OB04_RS14475	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OB04_RS14480	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OB04_RS14490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OB04_RS14500	COG3835	regulator
OB04_RS14505	COG0277	FAD linked oxidase domain protein
OB04_RS14510	COG0247	lactate metabolic process
OB04_RS14515	COG0346	lactoylglutathione lyase activity
OB04_RS14520	COG1966	Carbon starvation protein
OB04_RS14525	COG3534	alpha-L-arabinofuranosidase
OB04_RS14530	COG0395	ABC-type sugar transport system, permease component
OB04_RS14535	COG1175	transmembrane transport
OB04_RS14540	COG1653	transport
OB04_RS14545	COG0371	Dehydrogenase
OB04_RS14550	COG0647	UMP catabolic process
OB04_RS14555	COG0235	Class ii aldolase
OB04_RS14560	COG1069	ribulokinase activity
OB04_RS14565	COG2160	L-arabinose isomerase activity
OB04_RS14570	COG3507	Belongs to the glycosyl hydrolase 43 family
OB04_RS14575	COG1363	Peptidase, m42
OB04_RS14585	COG3326	Membrane
OB04_RS14590	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OB04_RS14595	COG0291	Belongs to the bacterial ribosomal protein bL35 family
OB04_RS14600	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OB04_RS14610	COG1346	cytolysis
OB04_RS14615	COG1380	Effector of murein hydrolase LrgA
OB04_RS14620	COG3279	Response regulator of the LytR AlgR family
OB04_RS14625	COG3275	phosphorelay sensor kinase activity
OB04_RS14630	COG1011	Hydrolase
OB04_RS14635	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OB04_RS14645	COG0398	Pfam SNARE associated Golgi protein
OB04_RS14650	COG1484	DNA-dependent DNA replication
OB04_RS14655	COG3611	Membrane attachment protein
OB04_RS14660	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OB04_RS14665	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
OB04_RS14670	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OB04_RS14675	COG1733	regulation of RNA biosynthetic process
OB04_RS14680	COG2814	Major facilitator Superfamily
OB04_RS14685	COG0656	L-ascorbic acid biosynthetic process
OB04_RS14690	COG0237	dephospho-CoA kinase activity
OB04_RS14705	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OB04_RS14710	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OB04_RS14710	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OB04_RS14715	COG5002	protein histidine kinase activity
OB04_RS14720	COG0745	RESPONSE REGULATOR receiver
OB04_RS14725	COG0039	L-malate dehydrogenase activity
OB04_RS14730	COG0538	isocitrate dehydrogenase activity
OB04_RS14735	COG0372	Belongs to the citrate synthase family
OB04_RS14740	COG2707	UPF0756 membrane protein
OB04_RS14745	COG0628	permease
OB04_RS14750	COG3030	protein affecting phage T7 exclusion by the F plasmid
OB04_RS14755	COG0469	pyruvate kinase activity
OB04_RS14760	COG0205	6-phosphofructokinase activity
OB04_RS14765	COG0825	malonyl-CoA metabolic process
OB04_RS14770	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OB04_RS14775	COG0281	malic enzyme
OB04_RS14780	COG0587	DNA-directed DNA polymerase activity
OB04_RS14800	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
OB04_RS14810	COG4109	DRTGG domain
OB04_RS14820	COG0730	response to heat
OB04_RS14825	COG1473	amidohydrolase
OB04_RS14830	COG0196	riboflavin kinase activity
OB04_RS14835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OB04_RS14840	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
OB04_RS14845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OB04_RS14850	COG1126	abc transporter atp-binding protein
OB04_RS14855	COG0765	amino acid transport
OB04_RS14860	COG0765	amino acid transport
OB04_RS14865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OB04_RS14870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OB04_RS14875	COG0454	-acetyltransferase
OB04_RS14880	COG0583	DNA-binding transcription factor activity
OB04_RS14885	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
OB04_RS14890	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_RS14900	COG0165	Argininosuccinate lyase
OB04_RS14905	COG0137	argininosuccinate synthase activity
OB04_RS14910	COG0521	Mo-molybdopterin cofactor biosynthetic process
OB04_RS14915	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OB04_RS14920	COG0827	DNA restriction-modification system
OB04_RS14925	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
OB04_RS14930	COG3874	Sporulation protein YtfJ
OB04_RS14940	COG1714	RDD family
OB04_RS14945	COG0616	signal peptide processing
OB04_RS14950	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OB04_RS14955	COG1574	metal-dependent hydrolase with the TIM-barrel fold
OB04_RS14960	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OB04_RS14970	COG0301	tRNA thio-modification
OB04_RS14975	COG1104	cysteine desulfurase activity
OB04_RS14980	COG1114	Component of the transport system for branched-chain amino acids
OB04_RS14985	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
OB04_RS14990	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
OB04_RS14995	COG1309	transcriptional regulator
OB04_RS15000	COG1956	GAF domain-containing protein
OB04_RS15005	COG2199	diguanylate cyclase activity
OB04_RS15005	COG2203	Gaf domain
OB04_RS15010	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OB04_RS15020	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OB04_RS15025	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OB04_RS15030	COG0454	-acetyltransferase
OB04_RS15035	COG0517	IMP dehydrogenase activity
OB04_RS15040	COG0123	including yeast histone deacetylase and acetoin utilization protein
OB04_RS15045	COG1360	Flagellar Motor Protein
OB04_RS15050	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
OB04_RS15055	COG1609	Transcriptional regulator
OB04_RS15060	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
OB04_RS15060	COG1605	Chorismate mutase
OB04_RS15065	COG3118	belongs to the thioredoxin family
OB04_RS15070	COG4980	gas vesicle protein
OB04_RS15075	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
OB04_RS15080	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OB04_RS15085	COG1674	ftsk spoiiie
OB04_RS15090	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OB04_RS15095	COG4848	Belongs to the UPF0354 family
OB04_RS15100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OB04_RS15110	COG1363	Peptidase, m42
OB04_RS15115	COG5584	Small secreted protein
OB04_RS15120	COG0281	malic enzyme
OB04_RS15125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OB04_RS15130	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OB04_RS15140	COG0510	thiamine kinase activity
OB04_RS15145	COG1523	belongs to the glycosyl hydrolase 13 family
OB04_RS15150	COG1597	lipid kinase activity
OB04_RS15160	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
OB04_RS15165	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OB04_RS15170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OB04_RS15175	COG2252	PERMEase
OB04_RS15180	COG4473	ABC transporter
OB04_RS15185	COG1131	(ABC) transporter
OB04_RS15190	COG1349	DNA-binding transcription factor activity
OB04_RS15195	COG1187	pseudouridine synthase activity
OB04_RS15200	COG2244	polysaccharide biosynthetic process
OB04_RS15205	COG2081	HI0933 family
OB04_RS15210	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OB04_RS15220	COG5578	integral membrane protein
OB04_RS15225	COG0673	inositol 2-dehydrogenase activity
OB04_RS15230	COG1653	transport
OB04_RS15235	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
OB04_RS15240	COG4209	transmembrane transport
OB04_RS15245	COG2207	Transcriptional regulator
OB04_RS15250	COG1653	transport
OB04_RS15255	COG0395	ABC-type sugar transport system, permease component
OB04_RS15260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OB04_RS15265	COG2124	cytochrome p450
OB04_RS15270	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OB04_RS15280	COG0156	8-amino-7-oxononanoate synthase activity
OB04_RS15285	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OB04_RS15295	COG1073	alpha beta
OB04_RS15300	COG1609	Transcriptional regulator
OB04_RS15305	COG1653	transport
OB04_RS15310	COG1175	transmembrane transport
OB04_RS15315	COG0395	ABC-type sugar transport system, permease component
OB04_RS15320	COG1486	melibiose metabolic process
OB04_RS15325	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OB04_RS15330	COG0495	leucyl-tRNA aminoacylation
OB04_RS15340	COG2202	Pas domain
OB04_RS15340	COG1366	Belongs to the anti-sigma-factor antagonist family
OB04_RS15345	COG2814	Major facilitator Superfamily
OB04_RS15350	COG2433	Pfam Transposase IS66
OB04_RS15355	COG0577	efflux transmembrane transporter activity
OB04_RS15360	COG1136	(ABC) transporter
OB04_RS15365	COG2205	protein histidine kinase activity
OB04_RS15370	COG0745	RESPONSE REGULATOR receiver
OB04_RS15375	COG0577	efflux transmembrane transporter activity
OB04_RS15380	COG1136	(ABC) transporter
OB04_RS15395	COG1131	(ABC) transporter
OB04_RS15400	COG1725	Transcriptional regulator
OB04_RS15415	COG1242	4 iron, 4 sulfur cluster binding
OB04_RS15420	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
OB04_RS15430	COG2267	carboxylic ester hydrolase activity
OB04_RS15435	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OB04_RS15440	COG1113	amino acid transport
OB04_RS15445	COG0367	asparagine synthase
OB04_RS15450	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OB04_RS15455	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
OB04_RS15465	COG1506	peptidase
OB04_RS15470	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OB04_RS15475	COG1116	anion transmembrane transporter activity
OB04_RS15480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OB04_RS15485	COG0494	nUDIX hydrolase
OB04_RS15490	COG4824	toxin secretion phage lysis holin
OB04_RS15495	COG0783	Belongs to the Dps family
OB04_RS15510	COG1854	S-ribosylhomocysteine lyase activity
OB04_RS15515	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
OB04_RS15520	COG0288	reversible hydration of carbon dioxide
OB04_RS15525	COG0254	rRNA binding
OB04_RS15530	COG1271	oxidase subunit
OB04_RS15535	COG1294	oxidase, subunit
OB04_RS15545	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OB04_RS15550	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OB04_RS15550	COG1321	iron dependent repressor
OB04_RS15555	COG1121	(ABC) transporter
OB04_RS15560	COG0803	Belongs to the bacterial solute-binding protein 9 family
OB04_RS15565	COG4948	Mandelate Racemase Muconate Lactonizing
OB04_RS15570	COG0318	PFAM AMP-dependent synthetase and ligase
OB04_RS15575	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
OB04_RS15580	COG0596	Alpha beta hydrolase
OB04_RS15585	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
OB04_RS15590	COG1169	isochorismate synthase
OB04_RS15595	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OB04_RS15600	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OB04_RS15605	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OB04_RS15610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OB04_RS15615	COG0438	transferase activity, transferring glycosyl groups
OB04_RS15625	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OB04_RS15630	COG0438	transferase activity, transferring glycosyl groups
OB04_RS15635	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OB04_RS15640	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
OB04_RS15645	COG0058	SHG alpha-glucan phosphorylase activity
OB04_RS15650	COG0297	glycogen (starch) synthase activity
OB04_RS15655	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
OB04_RS15660	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
OB04_RS15665	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OB04_RS15825	COG3859	Proton-coupled thiamine transporter YuaJ
OB04_RS15830	COG1247	-acetyltransferase
OB04_RS15835	COG2268	Band 7 protein
OB04_RS15840	COG1585	Membrane protein implicated in regulation of membrane protease activity
OB04_RS15845	COG2318	DinB family
OB04_RS15855	COG1454	alcohol dehydrogenase
OB04_RS15860	COG1012	belongs to the aldehyde dehydrogenase family
OB04_RS15865	COG1510	regulation of RNA biosynthetic process
OB04_RS15875	COG0569	domain protein
OB04_RS15880	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OB04_RS15885	COG4682	membrane
OB04_RS15890	COG1705	Flagellar rod assembly protein muramidase FlgJ
OB04_RS15895	COG0477	Major facilitator Superfamily
OB04_RS15900	COG5553	Cysteine dioxygenase type I
OB04_RS15910	COG1968	undecaprenyl-diphosphatase activity
OB04_RS15915	COG0628	permease
OB04_RS15920	COG0673	inositol 2-dehydrogenase activity
OB04_RS15925	COG4806	L-rhamnose isomerase
OB04_RS15930	COG3254	rhamnose metabolic process
OB04_RS15935	COG1070	Carbohydrate kinase
OB04_RS15940	COG1349	DNA-binding transcription factor activity
OB04_RS15945	COG3347	Dehydrogenase
OB04_RS15945	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_RS15950	COG0840	transmembrane signaling receptor activity
OB04_RS15955	COG0840	transmembrane signaling receptor activity
OB04_RS15960	COG0840	transmembrane signaling receptor activity
OB04_RS15965	COG0840	transmembrane signaling receptor activity
OB04_RS15980	COG0432	Pfam Uncharacterised protein family UPF0047
OB04_RS15985	COG0366	Alpha amylase catalytic
OB04_RS15990	COG1253	flavin adenine dinucleotide binding
OB04_RS15995	COG2738	Putative neutral zinc metallopeptidase
OB04_RS16010	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OB04_RS16025	COG0166	Belongs to the GPI family
OB04_RS16030	COG1979	alcohol dehydrogenase
OB04_RS16035	COG1979	alcohol dehydrogenase
OB04_RS16040	COG2155	Conserved Protein
OB04_RS16045	COG1098	S1 RNA binding domain
OB04_RS16050	COG0436	Aminotransferase
OB04_RS16055	COG1522	sequence-specific DNA binding
OB04_RS16060	COG2267	carboxylic ester hydrolase activity
OB04_RS16070	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
OB04_RS16075	COG2205	protein histidine kinase activity
OB04_RS16085	COG5018	Exonuclease
OB04_RS16095	COG2814	Major facilitator Superfamily
OB04_RS16100	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OB04_RS16105	COG3011	Protein conserved in bacteria
OB04_RS16115	COG3290	protein histidine kinase activity
OB04_RS16120	COG4565	transcriptional regulatory protein
OB04_RS16125	COG1744	ABC transporter substrate-binding protein PnrA-like
OB04_RS16130	COG3845	ABC transporter
OB04_RS16135	COG4603	Belongs to the binding-protein-dependent transport system permease family
OB04_RS16140	COG1079	Belongs to the binding-protein-dependent transport system permease family
OB04_RS16145	COG3493	citrate carrier protein
OB04_RS16155	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OB04_RS16155	COG2111	Na H antiporter
OB04_RS16160	COG2111	Na H antiporter
OB04_RS16165	COG1006	Multisubunit Na H antiporter MnhC subunit
OB04_RS16170	COG0651	ATP synthesis coupled electron transport
OB04_RS16175	COG1863	multisubunit Na H antiporter MnhE subunit
OB04_RS16180	COG2212	antiporter activity
OB04_RS16185	COG1320	monovalent cation:proton antiporter activity
OB04_RS16190	COG2050	protein possibly involved in aromatic compounds catabolism
OB04_RS16195	COG2197	response regulator
OB04_RS16200	COG4585	Histidine kinase
OB04_RS16210	COG0142	geranyltranstransferase activity
OB04_RS16225	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
OB04_RS16230	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
OB04_RS16235	COG1335	isochorismatase
OB04_RS16240	COG5506	Protein of unknown function (DUF1694)
OB04_RS16255	COG0628	permease
OB04_RS16270	COG1418	mRNA catabolic process
OB04_RS16275	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_RS16285	COG1511	domain protein
OB04_RS16290	COG0433	COG0433 Predicted ATPase
OB04_RS16290	COG1674	ftsk spoiiie
OB04_RS16295	COG4499	WXG100 protein secretion system (Wss), protein YukC
OB04_RS16300	COG5417	Belongs to the EsaB family
OB04_RS16305	COG4842	Belongs to the WXG100 family
OB04_RS16310	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
OB04_RS16310	COG2508	Transcriptional regulator
OB04_RS16315	COG0686	Belongs to the AlaDH PNT family
OB04_RS16320	COG5634	Uncharacterized conserved protein (DUF2278)
OB04_RS16325	COG3251	PFAM MbtH domain protein
OB04_RS16330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OB04_RS16335	COG1535	isochorismatase
OB04_RS16335	COG3433	isochorismatase activity
OB04_RS16340	COG1021	2,3-dihydroxybenzoate-AMP ligase
OB04_RS16345	COG1169	isochorismate synthase
OB04_RS16350	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_RS16355	COG2819	hydrolase of the alpha beta superfamily
OB04_RS16360	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OB04_RS16365	COG1268	BioY protein
OB04_RS16370	COG2056	Na+-H+ antiporter family
OB04_RS16375	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OB04_RS16380	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
OB04_RS16385	COG3584	3D domain protein
OB04_RS16400	COG1252	NADH dehydrogenase
OB04_RS16405	COG0492	ferredoxin-NADP+ reductase activity
OB04_RS16415	COG0516	GMP reductase activity
OB04_RS16420	COG2808	Putative FMN-binding domain
OB04_RS16425	COG0456	acetyltransferase
OB04_RS16430	COG0316	Belongs to the HesB IscA family
OB04_RS16435	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OB04_RS16440	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OB04_RS16445	COG4844	belongs to the
OB04_RS16450	COG1252	NADH dehydrogenase
OB04_RS16455	COG4837	Protein of unknown function (DUF1462)
OB04_RS16460	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
OB04_RS16465	COG0823	Involved in the tonB-independent uptake of proteins
OB04_RS16465	COG1506	peptidase
OB04_RS16465	COG4946	Tricorn protease homolog
OB04_RS16470	COG0083	homoserine kinase activity
OB04_RS16475	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OB04_RS16480	COG0460	homoserine dehydrogenase
OB04_RS16485	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OB04_RS16490	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
OB04_RS16495	COG0647	UMP catabolic process
OB04_RS16500	COG2445	Protein of unknown function DUF86
OB04_RS16505	COG4470	Protein conserved in bacteria
OB04_RS16515	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OB04_RS16520	COG0739	heme binding
OB04_RS16530	COG3377	Domain of unknown function (DUF1805)
OB04_RS16535	COG0737	Belongs to the 5'-nucleotidase family
OB04_RS16540	COG0730	response to heat
OB04_RS16545	COG1801	Protein of unknown function DUF72
OB04_RS16555	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OB04_RS16560	COG2508	Transcriptional regulator
OB04_RS16565	COG2233	PERMEase
OB04_RS16570	COG2233	PERMEase
OB04_RS16575	COG3648	Uricase
OB04_RS16575	COG3195	allantoin biosynthetic process
OB04_RS16580	COG2351	hydroxyisourate hydrolase activity
OB04_RS16590	COG2080	2 iron, 2 sulfur cluster binding
OB04_RS16595	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OB04_RS16600	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
OB04_RS16605	COG2068	MobA-Related Protein
OB04_RS16610	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
OB04_RS16615	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
OB04_RS16620	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OB04_RS16630	COG2356	endonuclease I
OB04_RS16635	COG3842	ATPase activity
OB04_RS16640	COG2188	Transcriptional regulator
OB04_RS16645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OB04_RS16650	COG0395	ABC-type sugar transport system, permease component
OB04_RS16655	COG1175	transmembrane transport
OB04_RS16660	COG1653	transport
OB04_RS16665	COG2222	sugar isomerase
OB04_RS16670	COG0322	excinuclease ABC activity
OB04_RS16675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OB04_RS16690	COG0719	Fe-S assembly protein
OB04_RS16695	COG0822	iron-sulfur transferase activity
OB04_RS16700	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OB04_RS16705	COG0719	Fe-S assembly protein
OB04_RS16710	COG0396	ATPase activity
OB04_RS16720	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OB04_RS16725	COG1464	Belongs to the NlpA lipoprotein family
OB04_RS16730	COG2011	ABC-type metal ion transport system permease component
OB04_RS16735	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OB04_RS16745	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OB04_RS16750	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
OB04_RS16760	COG0509	glycine decarboxylation via glycine cleavage system
OB04_RS16765	COG1393	Belongs to the ArsC family
OB04_RS16770	COG1960	acyl-CoA dehydrogenase activity
OB04_RS16775	COG0183	Belongs to the thiolase family
OB04_RS16780	COG1250	3-hydroxyacyl-CoA dehydrogenase
OB04_RS16780	COG1024	Enoyl-CoA hydratase
OB04_RS16800	COG5577	PFAM Coat F domain
OB04_RS16805	COG1846	Transcriptional regulator
OB04_RS16810	COG0477	Major facilitator Superfamily
OB04_RS16815	COG1942	4-Oxalocrotonate Tautomerase
OB04_RS16820	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_RS16825	COG0583	DNA-binding transcription factor activity
OB04_RS16835	COG1120	ATPase activity
OB04_RS16850	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_RS16855	COG0783	Belongs to the Dps family
OB04_RS16860	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OB04_RS16865	COG0745	RESPONSE REGULATOR receiver
OB04_RS16870	COG2205	protein histidine kinase activity
OB04_RS16870	COG2770	Histidine kinase
OB04_RS16880	COG1309	transcriptional regulator
OB04_RS16885	COG0114	fumarate hydratase activity
OB04_RS16895	COG0697	spore germination
OB04_RS16900	COG0814	amino acid
OB04_RS16910	COG2197	response regulator
OB04_RS16915	COG4585	Histidine kinase
OB04_RS16920	COG4758	membrane
OB04_RS16925	COG3595	metallopeptidase activity
OB04_RS16930	COG1842	Phage shock protein A
OB04_RS16935	COG4758	membrane
OB04_RS16940	COG2814	Major facilitator Superfamily
OB04_RS16945	COG2096	Adenosyltransferase
OB04_RS16950	COG1120	ATPase activity
OB04_RS16955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OB04_RS16960	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OB04_RS16970	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_RS16975	COG3386	PFAM SMP-30 Gluconolaconase
OB04_RS16980	COG2205	protein histidine kinase activity
OB04_RS16985	COG0745	RESPONSE REGULATOR receiver
OB04_RS16995	COG1191	sigma factor activity
OB04_RS17005	COG2140	Oxalate decarboxylase
OB04_RS17015	COG0577	efflux transmembrane transporter activity
OB04_RS17020	COG1136	(ABC) transporter
OB04_RS17025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OB04_RS17030	COG1120	ATPase activity
OB04_RS17035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OB04_RS17040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OB04_RS17045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OB04_RS17050	COG0531	amino acid
OB04_RS17060	COG1988	membrane-bound metal-dependent
OB04_RS17065	COG1368	sulfuric ester hydrolase activity
OB04_RS17070	COG1910	domain protein
OB04_RS17075	COG0725	ABC transporter, periplasmic molybdate-binding protein
OB04_RS17080	COG4149	molybdate abc transporter
OB04_RS17085	COG0656	L-ascorbic acid biosynthetic process
OB04_RS17095	COG0025	NhaP-type Na H and K H
OB04_RS17100	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OB04_RS17105	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OB04_RS17110	COG3973	AAA domain
OB04_RS17120	COG2860	membrane
OB04_RS17125	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
OB04_RS17130	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OB04_RS17135	COG2217	Heavy metal translocating P-type atpase
OB04_RS17140	COG2217	Heavy metal translocating P-type atpase
OB04_RS17145	COG2608	mercury ion transmembrane transporter activity
OB04_RS17150	COG1937	Protein conserved in bacteria
OB04_RS17155	COG0673	inositol 2-dehydrogenase activity
OB04_RS17160	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OB04_RS17165	COG1289	transmembrane transporter activity
OB04_RS17175	COG2076	Multidrug Resistance protein
OB04_RS17180	COG1309	transcriptional regulator
OB04_RS17185	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_RS17190	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OB04_RS17195	COG0557	exoribonuclease II activity
OB04_RS17200	COG1647	Serine aminopeptidase, S33
OB04_RS17205	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
OB04_RS17210	COG0596	Alpha beta hydrolase
OB04_RS17215	COG1476	TRANSCRIPTIONal
OB04_RS17220	COG1396	sequence-specific DNA binding
OB04_RS17225	COG1396	sequence-specific DNA binding
OB04_RS17230	COG1733	regulation of RNA biosynthetic process
OB04_RS17235	COG0840	transmembrane signaling receptor activity
OB04_RS17240	COG1174	glycine betaine transport
OB04_RS17245	COG1732	Glycine betaine
OB04_RS17250	COG1174	glycine betaine transport
OB04_RS17255	COG1125	glycine betaine transport
OB04_RS17255	COG0517	IMP dehydrogenase activity
OB04_RS17260	COG1510	regulation of RNA biosynthetic process
OB04_RS17280	COG5658	integral membrane protein
OB04_RS17285	COG0640	Transcriptional regulator
OB04_RS17290	COG1174	glycine betaine transport
OB04_RS17295	COG1732	Glycine betaine
OB04_RS17300	COG1174	glycine betaine transport
OB04_RS17305	COG0517	IMP dehydrogenase activity
OB04_RS17305	COG1125	glycine betaine transport
OB04_RS17310	COG1510	regulation of RNA biosynthetic process
OB04_RS17315	COG2095	MarC family integral membrane protein
OB04_RS17325	COG3064	Membrane
OB04_RS17330	COG4640	response to antibiotic
OB04_RS17335	COG0456	acetyltransferase
OB04_RS17340	COG0148	phosphopyruvate hydratase activity
OB04_RS17345	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
OB04_RS17350	COG0149	triose-phosphate isomerase activity
OB04_RS17355	COG0126	phosphoglycerate kinase activity
OB04_RS17365	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OB04_RS17370	COG2390	Transcriptional regulator
OB04_RS17375	COG2814	Major facilitator Superfamily
OB04_RS17380	COG1609	Transcriptional regulator
OB04_RS17385	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OB04_RS17390	COG0583	DNA-binding transcription factor activity
OB04_RS17395	COG0697	spore germination
OB04_RS17400	COG1113	amino acid transport
OB04_RS17405	COG3858	chitin binding
OB04_RS17410	COG1556	Lactate utilization protein
OB04_RS17415	COG1139	Iron-sulfur cluster binding protein
OB04_RS17420	COG0247	lactate metabolic process
OB04_RS17425	COG2197	response regulator
OB04_RS17430	COG4585	Histidine kinase
OB04_RS17435	COG0842	Transport permease protein
OB04_RS17440	COG1131	(ABC) transporter
OB04_RS17445	COG3867	Arabinogalactan endo-beta-1,4-galactanase
OB04_RS17450	COG1874	Beta-galactosidase
OB04_RS17455	COG3833	ABC-type maltose transport systems, permease component
OB04_RS17460	COG1175	transmembrane transport
OB04_RS17465	COG2182	Extracellular solute-binding protein
OB04_RS17470	COG1609	Transcriptional regulator
OB04_RS17475	COG2186	Transcriptional regulator
OB04_RS17480	COG1620	l-lactate permease
OB04_RS17485	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
OB04_RS17495	COG5039	Polysaccharide pyruvyl transferase
OB04_RS17500	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OB04_RS17505	COG0110	maltose O-acetyltransferase activity
OB04_RS17510	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OB04_RS17515	COG2244	polysaccharide biosynthetic process
OB04_RS17520	COG1216	Glycosyl transferase, family 2
OB04_RS17525	COG5039	Polysaccharide pyruvyl transferase
OB04_RS17530	COG1216	Glycosyl transferase, family 2
OB04_RS17540	COG0438	transferase activity, transferring glycosyl groups
OB04_RS17545	COG1215	transferase activity, transferring glycosyl groups
OB04_RS17550	COG0438	transferase activity, transferring glycosyl groups
OB04_RS17555	COG1086	Polysaccharide biosynthesis protein
OB04_RS17560	COG0489	protein tyrosine kinase activity
OB04_RS17565	COG3944	biosynthesis protein
OB04_RS17570	COG1396	sequence-specific DNA binding
OB04_RS17585	COG3479	Phenolic acid decarboxylase
OB04_RS17595	COG1794	racemase activity, acting on amino acids and derivatives
OB04_RS17600	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OB04_RS17605	COG1621	beta-fructofuranosidase activity
OB04_RS17610	COG1621	beta-fructofuranosidase activity
OB04_RS17615	COG0531	amino acid
OB04_RS17620	COG1309	transcriptional regulator
OB04_RS17625	COG2076	Multidrug Resistance protein
OB04_RS17630	COG2076	Multidrug Resistance protein
OB04_RS17640	COG0277	FAD linked oxidase domain protein
OB04_RS17645	COG3621	Patatin-like phospholipase
OB04_RS17655	COG0740	serine-type endopeptidase activity
OB04_RS17660	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OB04_RS17665	COG0366	Alpha amylase catalytic
OB04_RS17670	COG1554	hydrolase, family 65, central catalytic
OB04_RS17675	COG5521	maltodextrose utilization protein MalA
OB04_RS17680	COG3833	ABC-type maltose transport systems, permease component
OB04_RS17685	COG1175	transmembrane transport
OB04_RS17690	COG2182	Extracellular solute-binding protein
OB04_RS17700	COG1609	Transcriptional regulator
OB04_RS17705	COG1611	Belongs to the LOG family
OB04_RS17710	COG1694	Mazg nucleotide pyrophosphohydrolase
OB04_RS17715	COG0659	secondary active sulfate transmembrane transporter activity
OB04_RS17720	COG0288	reversible hydration of carbon dioxide
OB04_RS17725	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OB04_RS17730	COG0577	efflux transmembrane transporter activity
OB04_RS17735	COG1136	(ABC) transporter
OB04_RS17740	COG5002	protein histidine kinase activity
OB04_RS17745	COG0745	RESPONSE REGULATOR receiver
OB04_RS17755	COG2162	N-hydroxyarylamine O-acetyltransferase activity
OB04_RS17760	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OB04_RS17765	COG1481	regulation of sporulation
OB04_RS17770	COG0391	Required for morphogenesis under gluconeogenic growth conditions
OB04_RS17775	COG1660	Displays ATPase and GTPase activities
OB04_RS17780	COG1051	belongs to the nudix hydrolase family
OB04_RS17785	COG0492	ferredoxin-NADP+ reductase activity
OB04_RS17790	COG3883	PFAM NLP P60 protein
OB04_RS17790	COG0791	NLP P60 protein
OB04_RS17795	COG0457	Tetratricopeptide repeat
OB04_RS17800	COG1132	(ABC) transporter
OB04_RS17820	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OB04_RS17820	COG0140	phosphoribosyl-ATP diphosphatase activity
OB04_RS17825	COG0107	imidazoleglycerol-phosphate synthase activity
OB04_RS17830	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OB04_RS17835	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OB04_RS17840	COG0131	Imidazoleglycerol-phosphate dehydratase
OB04_RS17845	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OB04_RS17850	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OB04_RS17855	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
OB04_RS17860	COG4990	cell redox homeostasis
OB04_RS17865	COG5297	Belongs to the glycosyl hydrolase family 6
OB04_RS17870	COG0110	maltose O-acetyltransferase activity
OB04_RS17875	COG0546	phosphoglycolate phosphatase activity
OB04_RS17880	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
OB04_RS17885	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OB04_RS17890	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
OB04_RS17895	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
OB04_RS17900	COG0363	glucosamine-6-phosphate deaminase activity
OB04_RS17905	COG2188	Transcriptional regulator
OB04_RS17910	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OB04_RS17915	COG1950	PFAM Membrane protein of
OB04_RS17920	COG1983	PspC domain protein
OB04_RS17925	COG3595	metallopeptidase activity
OB04_RS17940	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OB04_RS17945	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OB04_RS17950	COG0556	nucleotide-excision repair
OB04_RS17955	COG4897	Protein conserved in bacteria
OB04_RS17960	COG3848	Pyruvate phosphate dikinase
OB04_RS17960	COG0574	Belongs to the PEP-utilizing enzyme family
OB04_RS17965	COG1309	transcriptional regulator
OB04_RS17970	COG2814	Major facilitator Superfamily
OB04_RS17975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OB04_RS17985	COG3409	Peptidoglycan-binding domain 1 protein
OB04_RS17985	COG0793	Belongs to the peptidase S41A family
OB04_RS17990	COG2177	Part of the ABC transporter FtsEX involved in
OB04_RS17995	COG2884	Cell division ATP-binding protein ftsE
OB04_RS18000	COG2010	Cytochrome c
OB04_RS18005	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OB04_RS18010	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
OB04_RS18015	COG0653	protein targeting
OB04_RS18020	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
OB04_RS18035	COG1516	flagellar protein fliS
OB04_RS18040	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
OB04_RS18045	COG1334	flagellar protein FlaG
OB04_RS18050	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OB04_RS18055	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
OB04_RS18060	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
OB04_RS18070	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OB04_RS18075	COG4786	Flagellar basal body rod
OB04_RS18075	COG1256	bacterial-type flagellum assembly
OB04_RS18080	COG3418	PFAM FlgN family protein
OB04_RS18085	COG2747	anti-sigma28 factor FlgM
OB04_RS18095	COG1040	competence protein
OB04_RS18105	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
OB04_RS18110	COG1307	EDD domain protein, DegV family
OB04_RS18115	COG2197	response regulator
OB04_RS18120	COG4585	Histidine kinase
OB04_RS18125	COG1739	Uncharacterized protein family UPF0029
OB04_RS18130	COG1316	TRANSCRIPTIONal
OB04_RS18135	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OB04_RS18140	COG0438	transferase activity, transferring glycosyl groups
OB04_RS18145	COG1215	transferase activity, transferring glycosyl groups
OB04_RS18150	COG3206	protein involved in exopolysaccharide biosynthesis
OB04_RS18155	COG3307	-O-antigen
OB04_RS18160	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OB04_RS18165	COG0297	glycogen (starch) synthase activity
OB04_RS18165	COG0438	transferase activity, transferring glycosyl groups
OB04_RS18170	COG2244	polysaccharide biosynthetic process
OB04_RS18180	COG0860	N-Acetylmuramoyl-L-alanine amidase
OB04_RS18180	COG2247	cell wall binding repeat
OB04_RS18185	COG2385	sporulation resulting in formation of a cellular spore
OB04_RS18185	COG2247	cell wall binding repeat
OB04_RS18195	COG1316	TRANSCRIPTIONal
OB04_RS18200	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
OB04_RS18205	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OB04_RS18210	COG1134	teichoic acid transport
OB04_RS18215	COG1682	transport, permease protein
OB04_RS18220	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OB04_RS18225	COG0438	transferase activity, transferring glycosyl groups
OB04_RS18230	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
OB04_RS18235	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
OB04_RS18240	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OB04_RS18250	COG4193	domain, Protein
OB04_RS18255	COG1482	cell wall glycoprotein biosynthetic process
OB04_RS18265	COG0697	spore germination
OB04_RS18270	COG0814	amino acid
OB04_RS18280	COG2814	Major facilitator Superfamily
OB04_RS18285	COG1316	TRANSCRIPTIONal
OB04_RS18290	COG0561	phosphatase activity
OB04_RS18295	COG0791	NLP P60 protein
OB04_RS18305	COG2843	Capsule synthesis protein
OB04_RS18315	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OB04_RS18320	COG1609	Transcriptional regulator
OB04_RS18325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OB04_RS18330	COG1869	D-ribose catabolic process
OB04_RS18335	COG1129	ABC transporter
OB04_RS18340	COG1172	Belongs to the binding-protein-dependent transport system permease family
OB04_RS18345	COG1879	ABC-type sugar transport system periplasmic component
OB04_RS18350	COG3103	Sh3 type 3 domain protein
OB04_RS18360	COG2249	NAD(P)H dehydrogenase (quinone) activity
OB04_RS18365	COG3527	Alpha-acetolactate decarboxylase
OB04_RS18370	COG0028	Belongs to the TPP enzyme family
OB04_RS18375	COG0583	DNA-binding transcription factor activity
OB04_RS18380	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OB04_RS18395	COG5337	Spore coat protein CotH
OB04_RS18405	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OB04_RS18415	COG0405	Gamma-glutamyltransferase
OB04_RS18420	COG1522	sequence-specific DNA binding
OB04_RS18425	COG2059	Chromate
OB04_RS18430	COG2059	Chromate
OB04_RS18440	COG0655	NAD(P)H dehydrogenase (quinone) activity
OB04_RS18445	COG0583	DNA-binding transcription factor activity
OB04_RS18460	COG5444	nuclease activity
OB04_RS18475	COG5444	nuclease activity
OB04_RS18490	COG3878	Protein conserved in bacteria
OB04_RS18495	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OB04_RS18500	COG4464	protein tyrosine phosphatase activity
OB04_RS18505	COG0489	protein tyrosine kinase activity
OB04_RS18510	COG3944	biosynthesis protein
OB04_RS18520	COG4715	Zinc finger, swim domain protein
OB04_RS18525	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OB04_RS18530	COG0561	phosphatase activity
OB04_RS18535	COG1349	DNA-binding transcription factor activity
OB04_RS18540	COG0629	single-stranded DNA binding
OB04_RS18555	COG3764	Sortase (surface protein transpeptidase)
OB04_RS18560	COG0745	RESPONSE REGULATOR receiver
OB04_RS18560	COG2972	Histidine kinase
OB04_RS18565	COG1970	mechanosensitive ion channel activity
OB04_RS18570	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OB04_RS18575	COG0457	Tetratricopeptide repeat
OB04_RS18580	COG4786	Flagellar basal body rod
OB04_RS18585	COG4786	Flagellar basal body rod
OB04_RS18590	COG1077	Cell shape determining protein MreB Mrl
OB04_RS18595	COG1609	Transcriptional regulator
OB04_RS18600	COG1846	Transcriptional regulator
OB04_RS18605	COG2814	Major facilitator Superfamily
OB04_RS18610	COG3420	alginic acid biosynthetic process
OB04_RS18615	COG1953	Uracil, thiamine, allantoin
OB04_RS18620	COG0477	Major facilitator Superfamily
OB04_RS18625	COG1335	isochorismatase
OB04_RS18635	COG0004	ammonium transporteR
OB04_RS18640	COG0347	Belongs to the P(II) protein family
OB04_RS18645	COG0671	phosphoesterase, PA-phosphatase related
OB04_RS18655	COG0739	heme binding
OB04_RS18660	COG1247	-acetyltransferase
OB04_RS18680	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OB04_RS18685	COG0789	Transcriptional regulator
OB04_RS18695	COG2910	NAD(P)H-binding
OB04_RS18700	COG1959	2 iron, 2 sulfur cluster binding
OB04_RS18705	COG0804	urea catabolic process
OB04_RS18710	COG0832	Belongs to the urease beta subunit family
OB04_RS18715	COG0831	urea catabolic process
OB04_RS18730	COG3237	CsbD-like
OB04_RS18735	COG1994	Peptidase M50
OB04_RS18740	COG0457	Tetratricopeptide repeat
OB04_RS18745	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OB04_RS18750	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OB04_RS18760	COG2304	oxidoreductase activity
OB04_RS18770	COG2304	oxidoreductase activity
OB04_RS18775	COG2385	sporulation resulting in formation of a cellular spore
OB04_RS18780	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OB04_RS18790	COG4836	Membrane
OB04_RS18800	COG0355	proton-transporting ATP synthase activity, rotational mechanism
OB04_RS18805	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OB04_RS18810	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OB04_RS18815	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OB04_RS18820	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OB04_RS18825	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OB04_RS18840	COG0356	it plays a direct role in the translocation of protons across the membrane
OB04_RS18850	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OB04_RS18855	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OB04_RS18860	COG4475	Protein of unknown function (DUF436)
OB04_RS18865	COG0698	ribose 5-phosphate isomerase
OB04_RS18870	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OB04_RS18875	COG1971	Probably functions as a manganese efflux pump
OB04_RS18880	COG0009	L-threonylcarbamoyladenylate synthase
OB04_RS18885	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
OB04_RS18905	COG2890	protein-(glutamine-N5) methyltransferase activity
OB04_RS18910	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OB04_RS18915	COG0346	lactoylglutathione lyase activity
OB04_RS18920	COG0789	Transcriptional regulator
OB04_RS18925	COG0679	Auxin Efflux Carrier
OB04_RS18930	COG0281	malic enzyme
OB04_RS18935	COG1435	thymidine kinase activity
OB04_RS18945	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
OB04_RS18955	COG1494	fructose-1,6-bisphosphatase
OB04_RS18960	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OB04_RS18965	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OB04_RS18970	COG0191	fructose-bisphosphate aldolase activity
OB04_RS18975	COG2204	response regulator
OB04_RS18980	COG4821	SIS domain
OB04_RS18985	COG0504	CTP synthase activity
OB04_RS18990	COG3343	RNA polymerase activity
OB04_RS18995	COG1960	acyl-CoA dehydrogenase activity
OB04_RS19000	COG2181	nitrate reductase activity
OB04_RS19000	COG0247	lactate metabolic process
OB04_RS19005	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OB04_RS19010	COG4294	response to UV
OB04_RS19020	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OB04_RS19025	COG1132	(ABC) transporter
OB04_RS19030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OB04_RS19035	COG2181	nitrate reductase activity
OB04_RS19040	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
OB04_RS19045	COG1140	nitrate reductase beta subunit
OB04_RS19050	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OB04_RS19055	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OB04_RS19065	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OB04_RS19070	COG2223	nitrite transmembrane transporter activity
OB04_RS19075	COG0018	arginyl-trna synthetase
OB04_RS19080	COG4506	Protein conserved in bacteria
OB04_RS19090	COG0535	radical SAM domain protein
OB04_RS19100	COG1131	(ABC) transporter
OB04_RS19105	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
OB04_RS19110	COG0612	Peptidase, M16
OB04_RS19115	COG0612	Peptidase, M16
OB04_RS19125	COG3391	amine dehydrogenase activity
OB04_RS19130	COG3391	amine dehydrogenase activity
OB04_RS19140	COG0457	Tetratricopeptide repeat
OB04_RS19170	COG1131	(ABC) transporter
OB04_RS19180	COG0010	Belongs to the arginase family
OB04_RS19185	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
OB04_RS19190	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OB04_RS19200	COG1994	Peptidase M50
OB04_RS19205	COG1942	4-Oxalocrotonate Tautomerase
OB04_RS19210	COG1846	Transcriptional regulator
OB04_RS19215	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OB04_RS19225	COG0477	Major facilitator Superfamily
OB04_RS19230	COG1959	2 iron, 2 sulfur cluster binding
OB04_RS19235	COG3465	dGTPase activity
OB04_RS19240	COG1078	dGTPase activity
OB04_RS19245	COG4844	belongs to the
OB04_RS19255	COG0697	spore germination
OB04_RS19260	COG0095	Lipoate-protein ligase
OB04_RS19265	COG0583	DNA-binding transcription factor activity
OB04_RS19270	COG0280	phosphate acetyltransferase
OB04_RS19275	COG3253	May function as heme-dependent peroxidase
OB04_RS19280	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_RS19285	COG0436	Aminotransferase
OB04_RS19290	COG2814	Major facilitator Superfamily
OB04_RS19295	COG0151	Belongs to the GarS family
OB04_RS19300	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_RS19305	COG1917	Cupin 2, conserved barrel domain protein
OB04_RS19310	COG0077	Prephenate dehydratase
OB04_RS19315	COG2814	Major facilitator Superfamily
OB04_RS19320	COG0833	amino acid
OB04_RS19325	COG4187	Peptidase family M20/M25/M40
OB04_RS19330	COG1012	belongs to the aldehyde dehydrogenase family
OB04_RS19335	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OB04_RS19345	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
OB04_RS19350	COG1091	dTDP-4-dehydrorhamnose reductase activity
OB04_RS19355	COG1088	dTDP-glucose 4,6-dehydratase activity
OB04_RS19360	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
OB04_RS19365	COG3980	spore coat polysaccharide biosynthesis protein
OB04_RS19370	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
OB04_RS19375	COG2089	acid synthase
OB04_RS19380	COG0456	acetyltransferase
OB04_RS19385	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OB04_RS19390	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OB04_RS19395	COG0463	Glycosyl transferase, family 2
OB04_RS19410	COG2363	Small membrane protein
OB04_RS19415	COG2233	PERMEase
OB04_RS19425	COG1012	belongs to the aldehyde dehydrogenase family
OB04_RS19430	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OB04_RS19435	COG1216	Glycosyl transferase, family 2
OB04_RS19450	COG1695	Transcriptional regulator
OB04_RS19455	COG0351	phosphomethylpyrimidine kinase
OB04_RS19465	COG1621	beta-fructofuranosidase activity
OB04_RS19470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OB04_RS19470	COG1263	PTS System
OB04_RS19475	COG2116	formate transmembrane transporter activity
OB04_RS19480	COG3711	transcriptional antiterminator
OB04_RS19490	COG1404	Belongs to the peptidase S8 family
OB04_RS19495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OB04_RS19500	COG0778	Nitroreductase
OB04_RS19505	COG0772	Belongs to the SEDS family
OB04_RS19515	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
OB04_RS19520	COG1845	cytochrome c oxidase, subunit III
OB04_RS19525	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OB04_RS19530	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OB04_RS19535	COG2261	transglycosylase associated protein
OB04_RS19540	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
OB04_RS19545	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
OB04_RS19550	COG2246	polysaccharide biosynthetic process
OB04_RS19555	COG1309	transcriptional regulator
OB04_RS19565	COG3162	membrane
OB04_RS19570	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OB04_RS19575	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OB04_RS19580	COG2837	iron assimilation
OB04_RS19585	COG2822	iron ion transport
OB04_RS19590	COG0672	)-iron permease
OB04_RS19595	COG0352	thiamine-phosphate diphosphorylase activity
OB04_RS19600	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
OB04_RS19605	COG0583	DNA-binding transcription factor activity
OB04_RS19610	COG1380	Effector of murein hydrolase LrgA
OB04_RS19615	COG1346	cytolysis
OB04_RS19620	COG2814	Major facilitator Superfamily
OB04_RS19625	COG4895	conserved protein (DUF2196)
OB04_RS19630	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OB04_RS19635	COG0346	lactoylglutathione lyase activity
OB04_RS19645	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OB04_RS19650	COG1404	Belongs to the peptidase S8 family
OB04_RS19655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OB04_RS19655	COG1263	PTS System
OB04_RS19660	COG3711	transcriptional antiterminator
OB04_RS19665	COG1442	glycosyl transferase family 8
OB04_RS19670	COG5522	Integral membrane protein (intg_mem_TP0381)
OB04_RS19675	COG1846	Transcriptional regulator
OB04_RS19680	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OB04_RS19685	COG2234	aminopeptidase activity
OB04_RS19700	COG2814	Major facilitator Superfamily
OB04_RS19705	COG2357	RelA SpoT domain protein
OB04_RS19710	COG1575	Belongs to the MenA family. Type 1 subfamily
OB04_RS19725	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OB04_RS19730	COG1696	Membrane protein involved in D-alanine export
OB04_RS19735	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OB04_RS19740	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
OB04_RS19745	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
OB04_RS19750	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OB04_RS19755	COG1486	melibiose metabolic process
OB04_RS19760	COG1447	Phosphotransferase system cellobiose-specific component IIA
OB04_RS19765	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OB04_RS19770	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OB04_RS19775	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OB04_RS19775	COG3711	transcriptional antiterminator
OB04_RS19785	COG2094	Belongs to the DNA glycosylase MPG family
OB04_RS19790	COG0753	catalase activity
OB04_RS19795	COG2814	Major facilitator Superfamily
OB04_RS19800	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
OB04_RS19805	COG1131	(ABC) transporter
OB04_RS19825	COG1595	DNA-templated transcription, initiation
OB04_RS19830	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OB04_RS19835	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OB04_RS19840	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
OB04_RS19845	COG4988	ABC transporter
OB04_RS19850	COG1294	oxidase, subunit
OB04_RS19855	COG1271	oxidase subunit
OB04_RS19860	COG3493	citrate carrier protein
OB04_RS19865	COG0501	Belongs to the peptidase M48B family
OB04_RS19875	COG0726	polysaccharide deacetylase
OB04_RS19880	COG3842	ATPase activity
OB04_RS19885	COG2508	Transcriptional regulator
OB04_RS19890	COG1012	belongs to the aldehyde dehydrogenase family
OB04_RS19895	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OB04_RS19905	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OB04_RS19915	COG4585	Histidine kinase
OB04_RS19920	COG2197	response regulator
OB04_RS19925	COG2195	Cleaves the N-terminal amino acid of tripeptides
OB04_RS19940	COG4894	glucomannan catabolic process
OB04_RS19945	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OB04_RS19950	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OB04_RS19955	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_RS19960	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OB04_RS19965	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OB04_RS19970	COG2610	gluconate transmembrane transporter activity
OB04_RS19980	COG0500	methyltransferase
OB04_RS19985	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OB04_RS20000	COG0753	catalase activity
OB04_RS20000	COG0693	protein deglycase activity
OB04_RS20005	COG2851	Citrate transporter
OB04_RS20010	COG2273	Hydrolase Family 16
OB04_RS20015	COG3711	transcriptional antiterminator
OB04_RS20025	COG2270	Major facilitator Superfamily
OB04_RS20030	COG0513	Belongs to the DEAD box helicase family
OB04_RS20035	COG2755	lipolytic protein G-D-S-L family
OB04_RS20035	COG3401	FG-GAP repeat protein
OB04_RS20095	COG3209	COG3209 Rhs family protein
OB04_RS20100	COG0697	spore germination
OB04_RS20105	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_RS20115	COG0589	response to stress
OB04_RS20120	COG2723	6-phospho-beta-galactosidase activity
OB04_RS20125	COG2190	(PTS) system
OB04_RS20125	COG1263	PTS System
OB04_RS20125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OB04_RS20140	COG5444	nuclease activity
OB04_RS20155	COG3507	Belongs to the glycosyl hydrolase 43 family
OB04_RS20165	COG2986	histidine ammonia-lyase
OB04_RS20170	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
OB04_RS20175	COG1228	amidohydrolase
OB04_RS20180	COG0010	Belongs to the arginase family
OB04_RS20185	COG0833	amino acid
OB04_RS20190	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
OB04_RS20195	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OB04_RS20200	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
OB04_RS20205	COG2390	Transcriptional regulator
OB04_RS20215	COG3192	ethanolamine utilization protein
OB04_RS20220	COG2079	MmgE PrpD family protein
OB04_RS20225	COG1473	amidohydrolase
OB04_RS20230	COG1126	abc transporter atp-binding protein
OB04_RS20235	COG0765	amino acid transport
OB04_RS20240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OB04_RS20245	COG0456	acetyltransferase
OB04_RS20250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OB04_RS20255	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
OB04_RS20260	COG0561	phosphatase activity
OB04_RS20290	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OB04_RS20295	COG5294	Protein conserved in bacteria
OB04_RS20300	COG0577	efflux transmembrane transporter activity
OB04_RS20305	COG1136	(ABC) transporter
OB04_RS20310	COG2205	protein histidine kinase activity
OB04_RS20315	COG0745	RESPONSE REGULATOR receiver
OB04_RS20320	COG0191	fructose-bisphosphate aldolase activity
OB04_RS20325	COG1082	Xylose isomerase domain protein TIM barrel
OB04_RS20330	COG1082	Xylose isomerase domain protein TIM barrel
OB04_RS20335	COG0673	inositol 2-dehydrogenase activity
OB04_RS20340	COG2814	Major facilitator Superfamily
OB04_RS20345	COG1082	Xylose isomerase domain protein TIM barrel
OB04_RS20350	COG3962	Belongs to the TPP enzyme family
OB04_RS20355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OB04_RS20365	COG1012	belongs to the aldehyde dehydrogenase family
OB04_RS20370	COG1349	DNA-binding transcription factor activity
OB04_RS20375	COG0667	Aldo Keto reductase
OB04_RS20390	COG2814	Major facilitator Superfamily
OB04_RS20395	COG0326	Molecular chaperone. Has ATPase activity
OB04_RS20405	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_RS20410	COG1309	transcriptional regulator
OB04_RS20415	COG1012	belongs to the aldehyde dehydrogenase family
OB04_RS20420	COG0456	acetyltransferase
OB04_RS20425	COG2850	peptidyl-arginine hydroxylation
OB04_RS20430	COG2226	methyltransferase
OB04_RS20445	COG0367	asparagine synthase
OB04_RS20450	COG2814	Major facilitator Superfamily
OB04_RS20455	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OB04_RS20465	COG1714	RDD family
OB04_RS20470	COG2311	Membrane
OB04_RS20475	COG1917	Cupin 2, conserved barrel domain protein
OB04_RS20480	COG1309	transcriptional regulator
OB04_RS20485	COG1028	Short-chain dehydrogenase reductase Sdr
OB04_RS20490	COG1846	Transcriptional regulator
OB04_RS20495	COG1380	Effector of murein hydrolase LrgA
OB04_RS20500	COG1346	cytolysis
OB04_RS20505	COG5039	Polysaccharide pyruvyl transferase
OB04_RS20510	COG1929	Belongs to the glycerate kinase type-1 family
OB04_RS20515	COG1802	Transcriptional regulator
OB04_RS20520	COG1070	Carbohydrate kinase
OB04_RS20525	COG2610	gluconate transmembrane transporter activity
OB04_RS20530	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OB04_RS20535	COG0450	alkyl hydroperoxide reductase
OB04_RS20540	COG3634	alkyl hydroperoxide reductase activity
OB04_RS20545	COG2723	6-phospho-beta-galactosidase activity
OB04_RS20550	COG2190	(PTS) system
OB04_RS20555	COG2188	Transcriptional regulator
OB04_RS20570	COG1131	(ABC) transporter
OB04_RS20575	COG1994	Peptidase M50
OB04_RS20580	COG0535	radical SAM domain protein
OB04_RS20590	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
OB04_RS20605	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OB04_RS20615	COG1063	alcohol dehydrogenase
OB04_RS20635	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
OB04_RS20640	COG0456	acetyltransferase
OB04_RS20645	COG0457	Tetratricopeptide repeat
OB04_RS20655	COG0010	Belongs to the arginase family
OB04_RS20660	COG0833	amino acid
OB04_RS20665	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OB04_RS20670	COG3829	transcription factor binding
OB04_RS20680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OB04_RS20685	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
OB04_RS20690	COG4853	Protein conserved in bacteria
OB04_RS20695	COG4863	YycH protein
OB04_RS20700	COG5002	protein histidine kinase activity
OB04_RS20705	COG0745	RESPONSE REGULATOR receiver
OB04_RS20735	COG0346	lactoylglutathione lyase activity
OB04_RS20740	COG0305	Participates in initiation and elongation during chromosome replication
OB04_RS20765	COG2807	transmembrane transport
OB04_RS20770	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OB04_RS20775	COG0359	binds to the 23S rRNA
OB04_RS20780	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
OB04_RS20785	COG4241	membrane
OB04_RS20795	COG5577	PFAM Coat F domain
OB04_RS20800	COG1733	regulation of RNA biosynthetic process
OB04_RS20805	COG1227	inorganic diphosphatase activity
OB04_RS20820	COG2271	Major facilitator Superfamily
OB04_RS20825	COG4978	Transcriptional regulator
OB04_RS20825	COG0789	Transcriptional regulator
OB04_RS20835	COG4319	ketosteroid isomerase
OB04_RS20840	COG1357	PFAM Pentapeptide repeats (8 copies)
OB04_RS20845	COG2814	Major facilitator Superfamily
OB04_RS20850	COG0583	DNA-binding transcription factor activity
OB04_RS20855	COG2153	protein acetylation
OB04_RS20865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OB04_RS20870	COG1846	Transcriptional regulator
OB04_RS20875	COG2153	protein acetylation
OB04_RS20880	COG2364	Membrane
OB04_RS20885	COG0456	acetyltransferase
OB04_RS20890	COG2315	Protein conserved in bacteria
OB04_RS20895	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OB04_RS20900	COG2814	Major facilitator Superfamily
OB04_RS20905	COG1331	Highly conserved protein containing a thioredoxin domain
OB04_RS20910	COG1266	CAAX protease self-immunity
OB04_RS20915	COG0477	Major facilitator Superfamily
OB04_RS20915	COG2814	Major facilitator Superfamily
OB04_RS20920	COG0110	maltose O-acetyltransferase activity
OB04_RS20925	COG0346	lactoylglutathione lyase activity
OB04_RS20930	COG1609	Transcriptional regulator
OB04_RS20935	COG0708	Exodeoxyribonuclease III
OB04_RS20940	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OB04_RS20945	COG0629	single-stranded DNA binding
OB04_RS20950	COG0360	Binds together with S18 to 16S ribosomal RNA
OB04_RS20955	COG0012	GTP binding
OB04_RS20960	COG0243	molybdopterin cofactor binding
OB04_RS20965	COG4481	Protein conserved in bacteria
OB04_RS20970	COG3949	Membrane
OB04_RS20980	COG1475	DNA binding
OB04_RS20985	COG1192	Involved in chromosome partitioning
OB04_RS20995	COG1475	DNA binding
OB04_RS21000	COG0357	Ribosomal RNA small subunit methyltransferase G
OB04_RS21005	COG0445	tRNA wobble uridine modification
OB04_RS21010	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OB04_RS21015	COG1847	R3H domain protein
OB04_RS21020	COG0706	membrane insertase activity
OB04_RS21025	COG0594	ribonuclease P activity
OB04_RS21035	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OB04_RS21040	COG0592	DNA-directed DNA polymerase activity
OB04_RS21045	COG2501	S4 domain
OB04_RS21050	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OB04_RS21060	COG0187	DNA topoisomerase II activity
OB04_RS21065	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OB04_RS21100	COG0517	IMP dehydrogenase activity
OB04_RS21100	COG0516	GMP reductase activity
OB04_RS21140	COG5412	phage tail tape measure protein
OB04_RS21140	COG3953	SLT domain
OB04_RS21160	COG1971	Probably functions as a manganese efflux pump