locus-tag	class	description
C7M16_RS00005	COG1472	Belongs to the glycosyl hydrolase 3 family
C7M16_RS00010	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M16_RS00015	COG1263	PTS System
C7M16_RS00015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M16_RS00020	COG1737	Transcriptional regulator
C7M16_RS00025	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C7M16_RS00035	COG1683	Conserved Protein
C7M16_RS00065	COG1595	DNA-templated transcription, initiation
C7M16_RS00070	COG5662	AntiSigma factor
C7M16_RS00075	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C7M16_RS00080	COG4856	YbbR-like protein
C7M16_RS00085	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7M16_RS00095	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C7M16_RS00105	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C7M16_RS00110	COG2169	Transcriptional regulator
C7M16_RS00115	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C7M16_RS00120	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C7M16_RS00125	COG3002	Belongs to the UPF0753 family
C7M16_RS00130	COG0288	reversible hydration of carbon dioxide
C7M16_RS00140	COG5609	conserved protein (DUF2294)
C7M16_RS00145	COG0640	Transcriptional regulator
C7M16_RS00150	COG2814	Major facilitator Superfamily
C7M16_RS00165	COG0596	Alpha beta hydrolase
C7M16_RS00170	COG0745	RESPONSE REGULATOR receiver
C7M16_RS00175	COG0642	Histidine kinase
C7M16_RS00185	COG0515	serine threonine protein kinase
C7M16_RS00200	COG1113	amino acid transport
C7M16_RS00215	COG2602	Beta-lactamase
C7M16_RS00220	COG2124	cytochrome p450
C7M16_RS00230	COG0531	amino acid
C7M16_RS00235	COG0584	glycerophosphoryl diester phosphodiesterase
C7M16_RS00240	COG2271	Major facilitator Superfamily
C7M16_RS00250	COG0456	acetyltransferase
C7M16_RS00250	COG1846	Transcriptional regulator
C7M16_RS00255	COG2271	Major facilitator Superfamily
C7M16_RS00270	COG3409	Peptidoglycan-binding domain 1 protein
C7M16_RS00275	COG0697	spore germination
C7M16_RS00280	COG2207	Transcriptional regulator
C7M16_RS00280	COG1917	Cupin 2, conserved barrel domain protein
C7M16_RS00285	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
C7M16_RS00290	COG3591	Belongs to the peptidase S1B family
C7M16_RS00300	COG0596	Alpha beta hydrolase
C7M16_RS00305	COG1183	phosphatidylcholine synthase activity
C7M16_RS00310	COG0586	Pfam SNARE associated Golgi protein
C7M16_RS00315	COG0688	phosphatidylethanolamine metabolic process
C7M16_RS00325	COG2312	Erythromycin esterase
C7M16_RS00335	COG1301	dicarboxylic acid transport
C7M16_RS00340	COG2190	(PTS) system
C7M16_RS00340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M16_RS00340	COG1263	PTS System
C7M16_RS00345	COG0363	glucosamine-6-phosphate deaminase activity
C7M16_RS00360	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7M16_RS00365	COG0833	amino acid
C7M16_RS00370	COG2040	homocysteine
C7M16_RS00380	COG1115	amino acid carrier protein
C7M16_RS00385	COG2066	Belongs to the glutaminase family
C7M16_RS00390	COG4191	Histidine kinase
C7M16_RS00395	COG0784	Response regulator, receiver
C7M16_RS00400	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C7M16_RS00405	COG1012	belongs to the aldehyde dehydrogenase family
C7M16_RS00410	COG2271	Major facilitator Superfamily
C7M16_RS00415	COG4948	Mandelate Racemase Muconate Lactonizing
C7M16_RS00420	COG2186	Transcriptional regulator
C7M16_RS00425	COG2721	sulfolactate sulfo-lyase activity
C7M16_RS00430	COG3173	Aminoglycoside phosphotransferase
C7M16_RS00440	COG0697	spore germination
C7M16_RS00445	COG0745	RESPONSE REGULATOR receiver
C7M16_RS00450	COG2205	protein histidine kinase activity
C7M16_RS00455	COG1131	(ABC) transporter
C7M16_RS00475	COG3773	Cell wall hydrolase
C7M16_RS00480	COG2304	oxidoreductase activity
C7M16_RS00490	COG3540	Alkaline phosphatase
C7M16_RS00495	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C7M16_RS00500	COG0805	protein transport
C7M16_RS00505	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
C7M16_RS00510	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C7M16_RS00515	COG0477	Major facilitator Superfamily
C7M16_RS00520	COG1309	transcriptional regulator
C7M16_RS00525	COG0252	asparaginase activity
C7M16_RS00530	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
C7M16_RS00535	COG1714	RDD family
C7M16_RS00540	COG3012	SEC-C Motif Domain Protein
C7M16_RS00540	COG1405	negative regulation of cell septum assembly
C7M16_RS00545	COG3290	protein histidine kinase activity
C7M16_RS00550	COG3279	Response regulator of the LytR AlgR family
C7M16_RS00555	COG4555	ABC transporter
C7M16_RS00560	COG1668	transmembrane transport
C7M16_RS00565	COG0667	Aldo Keto reductase
C7M16_RS00580	COG1595	DNA-templated transcription, initiation
C7M16_RS00585	COG1595	DNA-templated transcription, initiation
C7M16_RS00590	COG1876	peptidase activity
C7M16_RS00595	COG0457	Tetratricopeptide repeat
C7M16_RS00600	COG1028	Short-chain dehydrogenase reductase Sdr
C7M16_RS00605	COG0366	Alpha amylase catalytic
C7M16_RS00610	COG0803	Belongs to the bacterial solute-binding protein 9 family
C7M16_RS00615	COG1121	(ABC) transporter
C7M16_RS00620	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7M16_RS00625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M16_RS00630	COG2310	stress, protein
C7M16_RS00635	COG2310	stress, protein
C7M16_RS00640	COG2310	stress, protein
C7M16_RS00645	COG0861	Integral membrane protein TerC family
C7M16_RS00655	COG3853	Toxic anion resistance protein (TelA)
C7M16_RS00660	COG0477	Major facilitator Superfamily
C7M16_RS00665	COG2814	Major facilitator Superfamily
C7M16_RS00670	COG0640	Transcriptional regulator
C7M16_RS00675	COG0517	IMP dehydrogenase activity
C7M16_RS00675	COG4175	Glycine betaine
C7M16_RS00680	COG4176	ABC-type proline glycine betaine transport system permease component
C7M16_RS00685	COG2113	Glycine betaine
C7M16_RS00690	COG1473	amidohydrolase
C7M16_RS00695	COG1288	antiporter activity
C7M16_RS00705	COG0366	Alpha amylase catalytic
C7M16_RS00710	COG0039	L-malate dehydrogenase activity
C7M16_RS00715	COG1620	l-lactate permease
C7M16_RS00720	COG2814	Major facilitator Superfamily
C7M16_RS00725	COG1846	Transcriptional regulator
C7M16_RS00730	COG1280	lysine exporter protein (LysE YggA)
C7M16_RS00735	COG3403	YqcI/YcgG family
C7M16_RS00740	COG1113	amino acid transport
C7M16_RS00745	COG3665	Urea carboxylase-associated protein
C7M16_RS00750	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C7M16_RS00755	COG1660	Displays ATPase and GTPase activities
C7M16_RS00760	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C7M16_RS00765	COG2226	methyltransferase
C7M16_RS00770	COG0583	DNA-binding transcription factor activity
C7M16_RS00775	COG3458	cephalosporin-C deacetylase activity
C7M16_RS00780	COG3541	Predicted nucleotidyltransferase
C7M16_RS00785	COG0506	proline dehydrogenase activity
C7M16_RS00790	COG1012	belongs to the aldehyde dehydrogenase family
C7M16_RS00795	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M16_RS00800	COG2508	Transcriptional regulator
C7M16_RS00805	COG3689	TIGRFAM TIGR03943 family protein
C7M16_RS00810	COG0701	Predicted permease
C7M16_RS00815	COG2267	carboxylic ester hydrolase activity
C7M16_RS00820	COG0492	ferredoxin-NADP+ reductase activity
C7M16_RS00825	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C7M16_RS00825	COG1587	Uroporphyrinogen-III synthase
C7M16_RS00830	COG2146	nitrite reductase [NAD(P)H] activity
C7M16_RS00835	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7M16_RS00840	COG0243	molybdopterin cofactor binding
C7M16_RS00845	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7M16_RS00850	COG2223	nitrite transmembrane transporter activity
C7M16_RS00855	COG1469	GTP cyclohydrolase I activity
C7M16_RS00860	COG1376	ErfK ybiS ycfS ynhG family protein
C7M16_RS00870	COG0523	cobalamin synthesis protein
C7M16_RS00875	COG0765	amino acid transport
C7M16_RS00880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M16_RS00890	COG1714	RDD family
C7M16_RS00900	COG1846	Transcriptional regulator
C7M16_RS00910	COG3842	ATPase activity
C7M16_RS00915	COG2723	6-phospho-beta-galactosidase activity
C7M16_RS00925	COG3209	COG3209 Rhs family protein
C7M16_RS00930	COG0840	transmembrane signaling receptor activity
C7M16_RS00930	COG3290	protein histidine kinase activity
C7M16_RS00935	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C7M16_RS00940	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
C7M16_RS00945	COG1733	regulation of RNA biosynthetic process
C7M16_RS00950	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M16_RS00955	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M16_RS00960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M16_RS00965	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
C7M16_RS00970	COG2814	Major facilitator Superfamily
C7M16_RS00980	COG0697	spore germination
C7M16_RS00985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M16_RS00995	COG2364	Membrane
C7M16_RS01000	COG1126	abc transporter atp-binding protein
C7M16_RS01005	COG0765	amino acid transport
C7M16_RS01010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M16_RS01015	COG0583	DNA-binding transcription factor activity
C7M16_RS01020	COG0163	prenyltransferase activity
C7M16_RS01025	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C7M16_RS01045	COG3104	oligopeptide transport
C7M16_RS01050	COG5434	Belongs to the glycosyl hydrolase 28 family
C7M16_RS01060	COG0697	spore germination
C7M16_RS01070	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C7M16_RS01075	COG1136	(ABC) transporter
C7M16_RS01080	COG0577	efflux transmembrane transporter activity
C7M16_RS01085	COG0745	RESPONSE REGULATOR receiver
C7M16_RS01090	COG5002	protein histidine kinase activity
C7M16_RS01090	COG3850	Histidine kinase
C7M16_RS01095	COG0457	Tetratricopeptide repeat
C7M16_RS01115	COG0527	aspartate kinase activity
C7M16_RS01120	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M16_RS01125	COG4605	iron ion homeostasis
C7M16_RS01130	COG4604	ABC transporter, ATP-binding protein
C7M16_RS01135	COG4607	ABC-type enterochelin transport system periplasmic component
C7M16_RS01140	COG2814	Major facilitator Superfamily
C7M16_RS01145	COG1309	transcriptional regulator
C7M16_RS01150	COG0778	Nitroreductase
C7M16_RS01155	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C7M16_RS01160	COG0640	Transcriptional regulator
C7M16_RS01165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M16_RS01170	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C7M16_RS01175	COG1012	belongs to the aldehyde dehydrogenase family
C7M16_RS01180	COG4975	Glucose uptake
C7M16_RS01185	COG1028	Short-chain dehydrogenase reductase Sdr
C7M16_RS01190	COG4549	nuclear export factor GLE1
C7M16_RS01195	COG2372	response to copper ion
C7M16_RS01195	COG1276	copper resistance
C7M16_RS01200	COG1349	DNA-binding transcription factor activity
C7M16_RS01210	COG2213	PTS system mannitol-specific
C7M16_RS01215	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M16_RS01220	COG0246	Mannitol dehydrogenase
C7M16_RS01225	COG0473	3-isopropylmalate dehydrogenase activity
C7M16_RS01230	COG0681	Belongs to the peptidase S26 family
C7M16_RS01235	COG0412	Dienelactone hydrolase
C7M16_RS01240	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C7M16_RS01250	COG0561	phosphatase activity
C7M16_RS01255	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
C7M16_RS01260	COG1914	H( )-stimulated, divalent metal cation uptake system
C7M16_RS01265	COG4336	lyase activity
C7M16_RS01270	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C7M16_RS01275	COG1984	allophanate hydrolase subunit 2
C7M16_RS01280	COG1414	Transcriptional regulator
C7M16_RS01285	COG2755	lipolytic protein G-D-S-L family
C7M16_RS01295	COG2329	Antibiotic biosynthesis monooxygenase
C7M16_RS01300	COG0768	penicillin binding
C7M16_RS01305	COG4989	oxidoreductase activity
C7M16_RS01310	COG3711	transcriptional antiterminator
C7M16_RS01315	COG0318	PFAM AMP-dependent synthetase and ligase
C7M16_RS01320	COG2226	methyltransferase
C7M16_RS01325	COG1028	Short-chain dehydrogenase reductase Sdr
C7M16_RS01330	COG1917	Cupin 2, conserved barrel domain protein
C7M16_RS01335	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M16_RS01340	COG3871	stress protein (general stress protein 26)
C7M16_RS01350	COG2814	Major facilitator Superfamily
C7M16_RS01355	COG1522	sequence-specific DNA binding
C7M16_RS01360	COG0551	DNA topoisomerase type I activity
C7M16_RS01360	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C7M16_RS01365	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
C7M16_RS01370	COG3706	GGDEF domain
C7M16_RS01375	COG5298	Protein conserved in bacteria
C7M16_RS01380	COG1215	transferase activity, transferring glycosyl groups
C7M16_RS01390	COG0531	amino acid
C7M16_RS01395	COG0494	nUDIX hydrolase
C7M16_RS01400	COG0028	Belongs to the TPP enzyme family
C7M16_RS01410	COG1914	H( )-stimulated, divalent metal cation uptake system
C7M16_RS01415	COG2261	transglycosylase associated protein
C7M16_RS01420	COG4876	unkown
C7M16_RS01425	COG2217	Heavy metal translocating P-type atpase
C7M16_RS01430	COG3729	General stress protein
C7M16_RS01435	COG0662	Cupin 2, conserved barrel domain protein
C7M16_RS01440	COG2329	Antibiotic biosynthesis monooxygenase
C7M16_RS01445	COG3546	catalase activity
C7M16_RS01450	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C7M16_RS01455	COG3290	protein histidine kinase activity
C7M16_RS01460	COG4565	transcriptional regulatory protein
C7M16_RS01465	COG1301	dicarboxylic acid transport
C7M16_RS01470	COG0628	permease
C7M16_RS01475	COG1131	(ABC) transporter
C7M16_RS01480	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C7M16_RS01490	COG1960	acyl-CoA dehydrogenase activity
C7M16_RS01505	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C7M16_RS01510	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M16_RS01515	COG1181	Belongs to the D-alanine--D-alanine ligase family
C7M16_RS01520	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C7M16_RS01525	COG0513	Belongs to the DEAD box helicase family
C7M16_RS01530	COG3402	PFAM membrane-flanked domain
C7M16_RS01535	COG3428	Bacterial PH domain
C7M16_RS01540	COG0705	Rhomboid family
C7M16_RS01545	COG0736	holo-[acyl-carrier-protein] synthase activity
C7M16_RS01550	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C7M16_RS01555	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C7M16_RS01560	COG0864	Transcriptional regulator
C7M16_RS01565	COG2337	Toxic component of a toxin-antitoxin (TA) module
C7M16_RS01570	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M16_RS01575	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M16_RS01580	COG2172	sigma factor antagonist activity
C7M16_RS01585	COG2208	phosphoserine phosphatase activity
C7M16_RS01590	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M16_RS01595	COG2172	sigma factor antagonist activity
C7M16_RS01600	COG1191	sigma factor activity
C7M16_RS01605	COG2208	phosphoserine phosphatase activity
C7M16_RS01610	COG2183	response to ionizing radiation
C7M16_RS01620	COG3091	SprT-like family
C7M16_RS01660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M16_RS01700	COG1476	TRANSCRIPTIONal
C7M16_RS01730	COG1278	Cold shock
C7M16_RS01735	COG1329	Transcriptional regulator
C7M16_RS01745	COG1917	Cupin 2, conserved barrel domain protein
C7M16_RS01745	COG2207	Transcriptional regulator
C7M16_RS01750	COG0697	spore germination
C7M16_RS01755	COG2207	Transcriptional regulator
C7M16_RS01755	COG3708	Transcriptional regulator
C7M16_RS01760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M16_RS01765	COG0477	Major facilitator Superfamily
C7M16_RS01775	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
C7M16_RS01790	COG1309	transcriptional regulator
C7M16_RS01795	COG0697	spore germination
C7M16_RS01800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M16_RS01805	COG2030	dehydratase
C7M16_RS01810	COG3545	Serine hydrolase
C7M16_RS01815	COG1733	regulation of RNA biosynthetic process
C7M16_RS01820	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M16_RS01825	COG1733	regulation of RNA biosynthetic process
C7M16_RS01830	COG2249	NAD(P)H dehydrogenase (quinone) activity
C7M16_RS01835	COG2814	Major facilitator Superfamily
C7M16_RS01840	COG1309	transcriptional regulator
C7M16_RS01850	COG0640	Transcriptional regulator
C7M16_RS01855	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C7M16_RS01865	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M16_RS01870	COG0697	spore germination
C7M16_RS01875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M16_RS01880	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C7M16_RS01885	COG0640	Transcriptional regulator
C7M16_RS01890	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C7M16_RS01905	COG4585	Histidine kinase
C7M16_RS01910	COG2197	response regulator
C7M16_RS01915	COG2409	Drug exporters of the RND superfamily
C7M16_RS01920	COG0596	Alpha beta hydrolase
C7M16_RS01925	COG1811	Na channel or pump
C7M16_RS01930	COG4978	Transcriptional regulator
C7M16_RS01930	COG0789	Transcriptional regulator
C7M16_RS01935	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C7M16_RS01940	COG0778	Nitroreductase
C7M16_RS01945	COG0346	lactoylglutathione lyase activity
C7M16_RS01950	COG2259	Doxx family
C7M16_RS01955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M16_RS01970	COG2323	membrane
C7M16_RS01980	COG0071	Belongs to the small heat shock protein (HSP20) family
C7M16_RS01995	COG1309	transcriptional regulator
C7M16_RS02005	COG0456	acetyltransferase
C7M16_RS02015	COG0673	inositol 2-dehydrogenase activity
C7M16_RS02020	COG1609	Transcriptional regulator
C7M16_RS02025	COG2814	Major facilitator Superfamily
C7M16_RS02040	COG1113	amino acid transport
C7M16_RS02045	COG2318	DinB family
C7M16_RS02050	COG1846	Transcriptional regulator
C7M16_RS02055	COG1033	growth of symbiont in host cell
C7M16_RS02055	COG2409	Drug exporters of the RND superfamily
C7M16_RS02060	COG0778	Nitroreductase
C7M16_RS02065	COG1846	Transcriptional regulator
C7M16_RS02070	COG2814	Major facilitator Superfamily
C7M16_RS02075	COG0730	response to heat
C7M16_RS02080	COG1802	Transcriptional regulator
C7M16_RS02085	COG1388	LysM domain
C7M16_RS02085	COG3858	chitin binding
C7M16_RS02090	COG1819	glycosyl
C7M16_RS02100	COG1785	Belongs to the alkaline phosphatase family
C7M16_RS02105	COG5646	InterPro IPR014922
C7M16_RS02115	COG0454	-acetyltransferase
C7M16_RS02120	COG1078	dGTPase activity
C7M16_RS02125	COG1388	LysM domain
C7M16_RS02130	COG2814	Major facilitator Superfamily
C7M16_RS02135	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M16_RS02140	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7M16_RS02145	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M16_RS02150	COG2723	6-phospho-beta-galactosidase activity
C7M16_RS02155	COG2188	Transcriptional regulator
C7M16_RS02160	COG1940	carbohydrate kinase activity
C7M16_RS02165	COG1482	cell wall glycoprotein biosynthetic process
C7M16_RS02170	COG4124	Belongs to the glycosyl hydrolase 26 family
C7M16_RS02215	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C7M16_RS02220	COG0802	atpase or kinase
C7M16_RS02225	COG1214	PFAM Peptidase M22, glycoprotease
C7M16_RS02230	COG0456	acetyltransferase
C7M16_RS02235	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C7M16_RS02240	COG0488	(ABC) transporter
C7M16_RS02245	COG0315	cyclic pyranopterin monophosphate synthase activity
C7M16_RS02250	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
C7M16_RS02255	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C7M16_RS02260	COG0805	protein transport
C7M16_RS02270	COG1266	CAAX protease self-immunity
C7M16_RS02275	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
C7M16_RS02280	COG0459	protein refolding
C7M16_RS02290	COG1073	alpha beta
C7M16_RS02295	COG0457	Tetratricopeptide repeat
C7M16_RS02300	COG1063	alcohol dehydrogenase
C7M16_RS02305	COG2211	Major facilitator Superfamily
C7M16_RS02310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7M16_RS02315	COG1842	Phage shock protein A
C7M16_RS02320	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C7M16_RS02325	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
C7M16_RS02330	COG4260	virion core protein, lumpy skin disease virus
C7M16_RS02340	COG2814	Major facilitator Superfamily
C7M16_RS02345	COG1063	alcohol dehydrogenase
C7M16_RS02350	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C7M16_RS02355	COG0823	Involved in the tonB-independent uptake of proteins
C7M16_RS02370	COG2267	carboxylic ester hydrolase activity
C7M16_RS02380	COG2132	Multicopper oxidase
C7M16_RS02385	COG1113	amino acid transport
C7M16_RS02395	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C7M16_RS02400	COG0714	Associated with various cellular activities
C7M16_RS02405	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
C7M16_RS02410	COG1305	Transglutaminase-like
C7M16_RS02415	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C7M16_RS02415	COG0519	Catalyzes the synthesis of GMP from XMP
C7M16_RS02420	COG2252	PERMEase
C7M16_RS02425	COG3064	Membrane
C7M16_RS02435	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
C7M16_RS02445	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C7M16_RS02450	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C7M16_RS02455	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C7M16_RS02460	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C7M16_RS02465	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C7M16_RS02470	COG0047	phosphoribosylformylglycinamidine synthase activity
C7M16_RS02475	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C7M16_RS02480	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C7M16_RS02485	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C7M16_RS02490	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C7M16_RS02495	COG0138	bifunctional purine biosynthesis protein purh
C7M16_RS02500	COG0151	Belongs to the GarS family
C7M16_RS02505	COG1522	sequence-specific DNA binding
C7M16_RS02510	COG0531	amino acid
C7M16_RS02520	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C7M16_RS02525	COG1470	cell adhesion involved in biofilm formation
C7M16_RS02530	COG4496	protein, YerC YecD
C7M16_RS02535	COG0069	glutamate synthase activity
C7M16_RS02540	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
C7M16_RS02545	COG0210	DNA helicase
C7M16_RS02550	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C7M16_RS02555	COG4851	CamS sex pheromone cAM373 precursor
C7M16_RS02560	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7M16_RS02565	COG1285	pathogenesis
C7M16_RS02570	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M16_RS02575	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C7M16_RS02580	COG0154	amidase activity
C7M16_RS02585	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C7M16_RS02590	COG1309	transcriptional regulator
C7M16_RS02595	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C7M16_RS02600	COG1597	lipid kinase activity
C7M16_RS02605	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C7M16_RS02665	COG5444	nuclease activity
C7M16_RS02685	COG0457	Tetratricopeptide repeat
C7M16_RS02695	COG0217	transcriptional regulatory protein
C7M16_RS02705	COG1309	transcriptional regulator
C7M16_RS02710	COG3631	Ketosteroid isomerase-related protein
C7M16_RS02715	COG0702	epimerase
C7M16_RS02730	COG3546	catalase activity
C7M16_RS02735	COG0454	-acetyltransferase
C7M16_RS02745	COG5578	integral membrane protein
C7M16_RS02750	COG2972	Histidine kinase
C7M16_RS02755	COG4753	response regulator
C7M16_RS02755	COG2207	Transcriptional regulator
C7M16_RS02760	COG1653	transport
C7M16_RS02765	COG1175	transmembrane transport
C7M16_RS02770	COG0395	ABC-type sugar transport system, permease component
C7M16_RS02775	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
C7M16_RS02780	COG2207	Transcriptional regulator
C7M16_RS02785	COG2755	lipolytic protein G-D-S-L family
C7M16_RS02795	COG5578	integral membrane protein
C7M16_RS02800	COG3401	FG-GAP repeat protein
C7M16_RS02805	COG3401	FG-GAP repeat protein
C7M16_RS02810	COG2755	lipolytic protein G-D-S-L family
C7M16_RS02815	COG1874	Beta-galactosidase
C7M16_RS02825	COG1653	transport
C7M16_RS02830	COG4209	transmembrane transport
C7M16_RS02835	COG0395	ABC-type sugar transport system, permease component
C7M16_RS02840	COG1486	melibiose metabolic process
C7M16_RS02845	COG2323	membrane
C7M16_RS02850	COG2329	Antibiotic biosynthesis monooxygenase
C7M16_RS02855	COG0346	lactoylglutathione lyase activity
C7M16_RS02870	COG5583	Uncharacterized small protein (DUF2292)
C7M16_RS02875	COG0670	Belongs to the BI1 family
C7M16_RS02885	COG1846	Transcriptional regulator
C7M16_RS02890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C7M16_RS02905	COG2124	cytochrome p450
C7M16_RS02905	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C7M16_RS02910	COG1368	sulfuric ester hydrolase activity
C7M16_RS02915	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C7M16_RS02920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M16_RS02925	COG1442	glycosyl transferase family 8
C7M16_RS02930	COG1216	Glycosyl transferase, family 2
C7M16_RS02935	COG1442	glycosyl transferase family 8
C7M16_RS02940	COG2223	nitrite transmembrane transporter activity
C7M16_RS02945	COG1011	Hydrolase
C7M16_RS02950	COG0531	amino acid
C7M16_RS02955	COG1012	belongs to the aldehyde dehydrogenase family
C7M16_RS02960	COG0840	transmembrane signaling receptor activity
C7M16_RS02965	COG0488	(ABC) transporter
C7M16_RS02975	COG0789	Transcriptional regulator
C7M16_RS02980	COG2814	Major facilitator Superfamily
C7M16_RS02990	COG0488	(ABC) transporter
C7M16_RS02995	COG0513	Belongs to the DEAD box helicase family
C7M16_RS03000	COG0456	acetyltransferase
C7M16_RS03005	COG2130	NADP-dependent
C7M16_RS03010	COG2211	Major facilitator Superfamily
C7M16_RS03015	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C7M16_RS03020	COG1120	ATPase activity
C7M16_RS03025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M16_RS03030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M16_RS03035	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
C7M16_RS03050	COG3866	Pectate lyase
C7M16_RS03055	COG0471	metal ion transport
C7M16_RS03060	COG3290	protein histidine kinase activity
C7M16_RS03065	COG4565	transcriptional regulatory protein
C7M16_RS03070	COG3181	Tripartite tricarboxylate transporter family receptor
C7M16_RS03075	COG2851	Citrate transporter
C7M16_RS03080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M16_RS03085	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
C7M16_RS03090	COG1254	Belongs to the acylphosphatase family
C7M16_RS03095	COG2258	MOSC domain
C7M16_RS03115	COG0024	Methionine aminopeptidase
C7M16_RS03120	COG1263	PTS System
C7M16_RS03120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M16_RS03125	COG1368	sulfuric ester hydrolase activity
C7M16_RS03140	COG1115	amino acid carrier protein
C7M16_RS03145	COG0531	amino acid
C7M16_RS03160	COG0697	spore germination
C7M16_RS03165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M16_RS03165	COG1263	PTS System
C7M16_RS03170	COG0366	Alpha amylase catalytic
C7M16_RS03175	COG2188	Transcriptional regulator
C7M16_RS03180	COG0778	Nitroreductase
C7M16_RS03185	COG0737	Belongs to the 5'-nucleotidase family
C7M16_RS03190	COG0693	protein deglycase activity
C7M16_RS03195	COG2814	Major facilitator Superfamily
C7M16_RS03200	COG4840	Belongs to the UPF0435 family
C7M16_RS03205	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7M16_RS03210	COG4980	gas vesicle protein
C7M16_RS03215	COG1295	ribonuclease BN
C7M16_RS03220	COG0477	Major facilitator Superfamily
C7M16_RS03225	COG0387	Pfam Sodium calcium exchanger
C7M16_RS03235	COG0668	transmembrane transport
C7M16_RS03240	COG0535	radical SAM domain protein
C7M16_RS03250	COG0726	polysaccharide deacetylase
C7M16_RS03255	COG2084	Dehydrogenase
C7M16_RS03260	COG0598	Magnesium transport protein CorA
C7M16_RS03265	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C7M16_RS03270	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C7M16_RS03280	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7M16_RS03285	COG4637	Psort location Cytoplasmic, score
C7M16_RS03290	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C7M16_RS03295	COG0022	dehydrogenase e1 component
C7M16_RS03300	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7M16_RS03305	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7M16_RS03310	COG3284	Transcriptional regulator
C7M16_RS03320	COG1742	UPF0060 membrane protein
C7M16_RS03345	COG4842	Belongs to the WXG100 family
C7M16_RS03350	COG1486	melibiose metabolic process
C7M16_RS03355	COG1737	Transcriptional regulator
C7M16_RS03360	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M16_RS03360	COG1263	PTS System
C7M16_RS03365	COG1132	(ABC) transporter
C7M16_RS03370	COG1132	(ABC) transporter
C7M16_RS03375	COG2259	Doxx family
C7M16_RS03380	COG2514	catechol 2,3-dioxygenase activity
C7M16_RS03385	COG4585	Histidine kinase
C7M16_RS03390	COG2197	response regulator
C7M16_RS03395	COG1131	(ABC) transporter
C7M16_RS03400	COG1511	domain protein
C7M16_RS03400	COG0842	Transport permease protein
C7M16_RS03405	COG0842	Transport permease protein
C7M16_RS03415	COG1695	Transcriptional regulator
C7M16_RS03420	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
C7M16_RS03425	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
C7M16_RS03430	COG1309	transcriptional regulator
C7M16_RS03435	COG2814	Major facilitator Superfamily
C7M16_RS03440	COG2318	DinB family
C7M16_RS03445	COG2814	Major facilitator Superfamily
C7M16_RS03450	COG1846	Transcriptional regulator
C7M16_RS03455	COG0392	lysyltransferase activity
C7M16_RS03455	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
C7M16_RS03460	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M16_RS03465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M16_RS03470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M16_RS03475	COG0384	phenazine biosynthesis protein PhzF
C7M16_RS03480	COG0778	Nitroreductase
C7M16_RS03495	COG1090	epimerase
C7M16_RS03500	COG2137	regulation of response to DNA damage stimulus
C7M16_RS03510	COG2814	Major facilitator Superfamily
C7M16_RS03525	COG3103	Sh3 type 3 domain protein
C7M16_RS03530	COG5658	integral membrane protein
C7M16_RS03535	COG0596	Alpha beta hydrolase
C7M16_RS03540	COG0463	Glycosyl transferase, family 2
C7M16_RS03545	COG4485	Bacterial membrane protein, YfhO
C7M16_RS03550	COG1988	membrane-bound metal-dependent
C7M16_RS03555	COG1194	a g-specific adenine glycosylase
C7M16_RS03565	COG1028	Short-chain dehydrogenase reductase Sdr
C7M16_RS03580	COG3557	Belongs to the UPF0374 family
C7M16_RS03585	COG1132	(ABC) transporter
C7M16_RS03590	COG4129	membrane
C7M16_RS03595	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C7M16_RS03600	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C7M16_RS03605	COG0735	belongs to the Fur family
C7M16_RS03715	COG4326	sporulation control protein
C7M16_RS03725	COG5577	PFAM Coat F domain
C7M16_RS03730	COG3340	Belongs to the peptidase S51 family
C7M16_RS03735	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
C7M16_RS03740	COG0277	FAD linked oxidase domain protein
C7M16_RS03750	COG0753	catalase activity
C7M16_RS03755	COG1116	anion transmembrane transporter activity
C7M16_RS03760	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C7M16_RS03765	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C7M16_RS03770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M16_RS03780	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C7M16_RS03790	COG1476	TRANSCRIPTIONal
C7M16_RS03800	COG3382	B3 4 domain protein
C7M16_RS03805	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C7M16_RS03815	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C7M16_RS03820	COG0789	Transcriptional regulator
C7M16_RS03825	COG1664	Polymer-forming cytoskeletal
C7M16_RS03830	COG1664	Polymer-forming cytoskeletal
C7M16_RS03835	COG2766	serine protein kinase
C7M16_RS03840	COG2718	Belongs to the UPF0229 family
C7M16_RS03845	COG1846	Transcriptional regulator
C7M16_RS03850	COG1566	PFAM secretion protein HlyD family protein
C7M16_RS03855	COG2814	Major facilitator Superfamily
C7M16_RS03860	COG0655	NAD(P)H dehydrogenase (quinone) activity
C7M16_RS03880	COG1725	Transcriptional regulator
C7M16_RS03885	COG1131	(ABC) transporter
C7M16_RS03890	COG1131	(ABC) transporter
C7M16_RS03895	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C7M16_RS03900	COG1278	Cold shock
C7M16_RS03905	COG1464	Belongs to the NlpA lipoprotein family
C7M16_RS03910	COG3706	GGDEF domain
C7M16_RS03915	COG1823	symporter activity
C7M16_RS03935	COG5577	PFAM Coat F domain
C7M16_RS03940	COG0737	Belongs to the 5'-nucleotidase family
C7M16_RS03940	COG1525	nuclease
C7M16_RS03940	COG4085	toxin activity
C7M16_RS03945	COG3764	Sortase (surface protein transpeptidase)
C7M16_RS03950	COG0564	pseudouridine synthase activity
C7M16_RS03960	COG0517	IMP dehydrogenase activity
C7M16_RS03965	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7M16_RS03970	COG3153	acetyltransferase
C7M16_RS03970	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7M16_RS03975	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C7M16_RS03980	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
C7M16_RS03985	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C7M16_RS03990	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C7M16_RS03995	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C7M16_RS04000	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7M16_RS04005	COG4585	Histidine kinase
C7M16_RS04005	COG2203	Gaf domain
C7M16_RS04010	COG2197	response regulator
C7M16_RS04015	COG0431	NADPH-dependent FMN reductase
C7M16_RS04030	COG1388	LysM domain
C7M16_RS04030	COG0791	NLP P60 protein
C7M16_RS04035	COG1959	2 iron, 2 sulfur cluster binding
C7M16_RS04040	COG0668	transmembrane transport
C7M16_RS04045	COG2719	SpoVR family
C7M16_RS04050	COG1785	Belongs to the alkaline phosphatase family
C7M16_RS04055	COG1388	LysM domain
C7M16_RS04055	COG0791	NLP P60 protein
C7M16_RS04060	COG0583	DNA-binding transcription factor activity
C7M16_RS04065	COG0372	Belongs to the citrate synthase family
C7M16_RS04070	COG1028	Short-chain dehydrogenase reductase Sdr
C7M16_RS04075	COG0531	amino acid
C7M16_RS04080	COG0733	neurotransmitter:sodium symporter activity
C7M16_RS04085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M16_RS04090	COG0456	acetyltransferase
C7M16_RS04105	COG1595	DNA-templated transcription, initiation
C7M16_RS04110	COG0667	Aldo Keto reductase
C7M16_RS04115	COG0204	Acyl-transferase
C7M16_RS04120	COG1253	flavin adenine dinucleotide binding
C7M16_RS04125	COG0789	Transcriptional regulator
C7M16_RS04130	COG0436	Aminotransferase
C7M16_RS04135	COG1253	flavin adenine dinucleotide binding
C7M16_RS04140	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C7M16_RS04145	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C7M16_RS04150	COG0584	glycerophosphoryl diester phosphodiesterase
C7M16_RS04160	COG0668	transmembrane transport
C7M16_RS04165	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C7M16_RS04170	COG0726	polysaccharide deacetylase
C7M16_RS04175	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7M16_RS04180	COG1757	Na H antiporter
C7M16_RS04185	COG0589	response to stress
C7M16_RS04195	COG1132	(ABC) transporter
C7M16_RS04200	COG1132	(ABC) transporter
C7M16_RS04205	COG0702	epimerase
C7M16_RS04225	COG0189	ligase activity
C7M16_RS04230	COG0189	ligase activity
C7M16_RS04235	COG4399	Belongs to the UPF0754 family
C7M16_RS04240	COG3679	Belongs to the UPF0342 family
C7M16_RS04245	COG4335	DNA alkylation repair
C7M16_RS04250	COG0561	phosphatase activity
C7M16_RS04255	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C7M16_RS04260	COG0475	glutathione-regulated potassium exporter activity
C7M16_RS04265	COG0490	domain, Protein
C7M16_RS04275	COG1024	Enoyl-CoA hydratase
C7M16_RS04285	COG4152	abc transporter atp-binding protein
C7M16_RS04290	COG1668	transmembrane transport
C7M16_RS04295	COG0420	3'-5' exonuclease activity
C7M16_RS04300	COG4717	serine-type aminopeptidase activity
C7M16_RS04305	COG3481	metal-dependent phosphohydrolase, HD sub domain
C7M16_RS04315	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C7M16_RS04345	COG1846	Transcriptional regulator
C7M16_RS04350	COG4980	gas vesicle protein
C7M16_RS04365	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C7M16_RS04370	COG0537	adenosine 5'-monophosphoramidase activity
C7M16_RS04375	COG1131	(ABC) transporter
C7M16_RS04380	COG4473	ABC transporter
C7M16_RS04390	COG1473	amidohydrolase
C7M16_RS04395	COG3069	C4-dicarboxylate transmembrane transporter activity
C7M16_RS04405	COG2329	Antibiotic biosynthesis monooxygenase
C7M16_RS04410	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7M16_RS04415	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
C7M16_RS04430	COG1309	transcriptional regulator
C7M16_RS04435	COG1511	domain protein
C7M16_RS04440	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7M16_RS04445	COG4377	Putative membrane peptidase family (DUF2324)
C7M16_RS04455	COG1363	Peptidase, m42
C7M16_RS04460	COG4405	Protein conserved in bacteria
C7M16_RS04465	COG1301	dicarboxylic acid transport
C7M16_RS04475	COG1234	tRNA 3'-trailer cleavage
C7M16_RS04480	COG0095	Lipoate-protein ligase
C7M16_RS04485	COG0702	epimerase
C7M16_RS04490	COG0318	PFAM AMP-dependent synthetase and ligase
C7M16_RS04500	COG0501	Belongs to the peptidase M48B family
C7M16_RS04505	COG1404	Belongs to the peptidase S8 family
C7M16_RS04510	COG0456	acetyltransferase
C7M16_RS04515	COG0604	alcohol dehydrogenase
C7M16_RS04520	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
C7M16_RS04525	COG0406	alpha-ribazole phosphatase activity
C7M16_RS04530	COG0183	Belongs to the thiolase family
C7M16_RS04535	COG0318	PFAM AMP-dependent synthetase and ligase
C7M16_RS04540	COG1268	BioY protein
C7M16_RS04545	COG0840	transmembrane signaling receptor activity
C7M16_RS04550	COG0723	plastoquinol--plastocyanin reductase activity
C7M16_RS04550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7M16_RS04555	COG1028	Short-chain dehydrogenase reductase Sdr
C7M16_RS04565	COG4903	ComK protein
C7M16_RS04570	COG1028	Short-chain dehydrogenase reductase Sdr
C7M16_RS04580	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M16_RS04595	COG0398	Pfam SNARE associated Golgi protein
C7M16_RS04600	COG0681	Belongs to the peptidase S26 family
C7M16_RS04605	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C7M16_RS04610	COG1846	Transcriptional regulator
C7M16_RS04615	COG0738	Major facilitator superfamily
C7M16_RS04620	COG0673	inositol 2-dehydrogenase activity
C7M16_RS04625	COG0561	phosphatase activity
C7M16_RS04630	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C7M16_RS04635	COG1609	Transcriptional regulator
C7M16_RS04640	COG3180	Ammonia monooxygenase
C7M16_RS04645	COG2814	Major facilitator Superfamily
C7M16_RS04645	COG0477	Major facilitator Superfamily
C7M16_RS04650	COG4533	DNA binding
C7M16_RS04660	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
C7M16_RS04665	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
C7M16_RS04670	COG1074	ATP-dependent DNA helicase activity
C7M16_RS04675	COG0420	3'-5' exonuclease activity
C7M16_RS04680	COG0419	ATPase involved in DNA repair
C7M16_RS04685	COG1403	HNH endonuclease
C7M16_RS04725	COG5337	Spore coat protein CotH
C7M16_RS04730	COG0179	Fumarylacetoacetate (FAA) hydrolase
C7M16_RS04740	COG1404	Belongs to the peptidase S8 family
C7M16_RS04750	COG0367	asparagine synthase
C7M16_RS04755	COG2318	DinB family
C7M16_RS04760	COG1562	ergosterol biosynthetic process
C7M16_RS04765	COG0534	Mate efflux family protein
C7M16_RS04770	COG1917	Cupin 2, conserved barrel domain protein
C7M16_RS04770	COG2207	Transcriptional regulator
C7M16_RS04775	COG1609	Transcriptional regulator
C7M16_RS04780	COG0673	inositol 2-dehydrogenase activity
C7M16_RS04785	COG2318	DinB family
C7M16_RS04790	COG1279	arginine transmembrane transporter activity
C7M16_RS04795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M16_RS04800	COG1357	PFAM Pentapeptide repeats (8 copies)
C7M16_RS04805	COG2267	carboxylic ester hydrolase activity
C7M16_RS04810	COG0529	Catalyzes the synthesis of activated sulfate
C7M16_RS04815	COG2046	Belongs to the sulfate adenylyltransferase family
C7M16_RS04820	COG0175	sulfate reduction
C7M16_RS04825	COG2045	Belongs to the ComB family
C7M16_RS04830	COG1809	phosphosulfolactate synthase activity
C7M16_RS04835	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M16_RS04840	COG4948	Mandelate Racemase Muconate Lactonizing
C7M16_RS04845	COG2814	Major facilitator Superfamily
C7M16_RS04850	COG0454	-acetyltransferase
C7M16_RS04855	COG2153	protein acetylation
C7M16_RS04860	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C7M16_RS04860	COG0646	methionine synthase
C7M16_RS04865	COG1666	GTP binding
C7M16_RS04870	COG2996	Protein conserved in bacteria
C7M16_RS04890	COG1695	Transcriptional regulator
C7M16_RS04905	COG3227	Zinc metalloprotease (Elastase)
C7M16_RS04910	COG1307	EDD domain protein, DegV family
C7M16_RS04915	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M16_RS04930	COG0561	phosphatase activity
C7M16_RS04935	COG1073	alpha beta
C7M16_RS04940	COG2151	metal-sulfur cluster biosynthetic enzyme
C7M16_RS04950	COG0277	FAD linked oxidase domain protein
C7M16_RS04955	COG2271	Major facilitator Superfamily
C7M16_RS04960	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C7M16_RS04975	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C7M16_RS04980	COG0505	Belongs to the CarA family
C7M16_RS04985	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C7M16_RS04990	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C7M16_RS05005	COG2267	carboxylic ester hydrolase activity
C7M16_RS05015	COG1744	ABC transporter substrate-binding protein PnrA-like
C7M16_RS05030	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7M16_RS05035	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C7M16_RS05040	COG5504	Zn-dependent protease
C7M16_RS05045	COG0444	Belongs to the ABC transporter superfamily
C7M16_RS05050	COG4608	Belongs to the ABC transporter superfamily
C7M16_RS05060	COG0601	transmembrane transport
C7M16_RS05065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7M16_RS05075	COG0180	Tryptophanyl-tRNA synthetase
C7M16_RS05080	COG4166	transmembrane transport
C7M16_RS05085	COG0601	transmembrane transport
C7M16_RS05090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7M16_RS05095	COG0444	Belongs to the ABC transporter superfamily
C7M16_RS05100	COG4608	Belongs to the ABC transporter superfamily
C7M16_RS05105	COG2814	Major facilitator Superfamily
C7M16_RS05110	COG0456	acetyltransferase
C7M16_RS05115	COG1393	Belongs to the ArsC family
C7M16_RS05120	COG0861	Integral membrane protein TerC family
C7M16_RS05130	COG4862	establishment of competence for transformation
C7M16_RS05140	COG4469	Competence protein
C7M16_RS05145	COG1164	Oligoendopeptidase f
C7M16_RS05160	COG2346	COG2346, Truncated hemoglobins
C7M16_RS05165	COG0741	lytic transglycosylase activity
C7M16_RS05170	COG4116	CYTH
C7M16_RS05180	COG2357	RelA SpoT domain protein
C7M16_RS05185	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C7M16_RS05190	COG0564	pseudouridine synthase activity
C7M16_RS05195	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C7M16_RS05200	COG0475	glutathione-regulated potassium exporter activity
C7M16_RS05200	COG0569	domain protein
C7M16_RS05205	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C7M16_RS05210	COG0352	thiamine-phosphate diphosphorylase activity
C7M16_RS05215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7M16_RS05220	COG2104	thiamine diphosphate biosynthetic process
C7M16_RS05225	COG2022	thiamine diphosphate biosynthetic process
C7M16_RS05230	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C7M16_RS05235	COG0351	phosphomethylpyrimidine kinase
C7M16_RS05240	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C7M16_RS05295	COG0210	DNA helicase
C7M16_RS05305	COG2153	protein acetylation
C7M16_RS05310	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C7M16_RS05315	COG2382	esterase
C7M16_RS05320	COG0626	cystathionine gamma-synthase activity
C7M16_RS05325	COG0626	cystathionine gamma-synthase activity
C7M16_RS05330	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M16_RS05335	COG5505	Protein of unknown function (DUF819)
C7M16_RS05355	COG5444	nuclease activity
C7M16_RS05375	COG0457	Tetratricopeptide repeat
C7M16_RS05380	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C7M16_RS05385	COG1028	Short-chain dehydrogenase reductase Sdr
C7M16_RS05395	COG3711	transcriptional antiterminator
C7M16_RS05395	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M16_RS05400	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M16_RS05400	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M16_RS05400	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M16_RS05405	COG1482	cell wall glycoprotein biosynthetic process
C7M16_RS05415	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M16_RS05425	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C7M16_RS05440	COG0109	protoheme IX farnesyltransferase activity
C7M16_RS05450	COG0726	polysaccharide deacetylase
C7M16_RS05465	COG5504	Zn-dependent protease
C7M16_RS05470	COG2205	protein histidine kinase activity
C7M16_RS05480	COG3383	formate dehydrogenase (NAD+) activity
C7M16_RS05485	COG2427	Protein of unknown function (DUF1641)
C7M16_RS05495	COG1051	belongs to the nudix hydrolase family
C7M16_RS05505	COG2124	cytochrome p450
C7M16_RS05510	COG1819	glycosyl
C7M16_RS05520	COG1587	Uroporphyrinogen-III synthase
C7M16_RS05525	COG0390	transport system, permease component
C7M16_RS05530	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7M16_RS05535	COG0697	spore germination
C7M16_RS05540	COG4297	protein containing double-stranded beta helix domain
C7M16_RS05550	COG1252	NADH dehydrogenase
C7M16_RS05555	COG1904	glucuronate isomerase
C7M16_RS05560	COG2211	Major facilitator Superfamily
C7M16_RS05565	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C7M16_RS05570	COG1063	alcohol dehydrogenase
C7M16_RS05575	COG1312	Catalyzes the dehydration of D-mannonate
C7M16_RS05580	COG1028	Short-chain dehydrogenase reductase Sdr
C7M16_RS05585	COG2271	Major facilitator Superfamily
C7M16_RS05590	COG1609	Transcriptional regulator
C7M16_RS05595	COG0246	Mannitol dehydrogenase
C7M16_RS05600	COG2721	sulfolactate sulfo-lyase activity
C7M16_RS05605	COG0730	response to heat
C7M16_RS05610	COG2318	DinB family
C7M16_RS05615	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C7M16_RS05620	COG0457	Tetratricopeptide repeat
C7M16_RS05630	COG2350	Protein conserved in bacteria
C7M16_RS05635	COG3409	Peptidoglycan-binding domain 1 protein
C7M16_RS05635	COG5632	N-Acetylmuramoyl-L-alanine amidase
C7M16_RS05635	COG1388	LysM domain
C7M16_RS05645	COG4195	phage-related replication protein
C7M16_RS05650	COG3546	catalase activity
C7M16_RS05655	COG2856	Zn peptidase
C7M16_RS05660	COG1396	sequence-specific DNA binding
C7M16_RS05670	COG1522	sequence-specific DNA binding
C7M16_RS05675	COG1484	DNA-dependent DNA replication
C7M16_RS05695	COG1595	DNA-templated transcription, initiation
C7M16_RS05700	COG3728	DNA packaging
C7M16_RS05700	COG5484	DNA packaging
C7M16_RS05705	COG1783	phage Terminase large subunit
C7M16_RS05710	COG5518	Phage portal protein
C7M16_RS05715	COG0338	D12 class N6 adenine-specific DNA methyltransferase
C7M16_RS05720	COG4653	Phage capsid family
C7M16_RS05770	COG3953	SLT domain
C7M16_RS05770	COG5412	phage tail tape measure protein
C7M16_RS05775	COG1652	LysM domain
C7M16_RS05780	COG4193	domain, Protein
C7M16_RS05790	COG3628	GPW Gp25 family protein
C7M16_RS05795	COG3299	homolog of phage Mu protein gp47
C7M16_RS05800	COG3778	Protein conserved in bacteria
C7M16_RS05840	COG3409	Peptidoglycan-binding domain 1 protein
C7M16_RS05840	COG5632	N-Acetylmuramoyl-L-alanine amidase
C7M16_RS05860	COG0306	phosphate transporter
C7M16_RS05865	COG1392	Phosphate transport regulator
C7M16_RS05870	COG0531	amino acid
C7M16_RS05875	COG0346	lactoylglutathione lyase activity
C7M16_RS05880	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C7M16_RS05885	COG0463	Glycosyl transferase, family 2
C7M16_RS05890	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M16_RS05895	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7M16_RS05900	COG2362	D-Aminopeptidase
C7M16_RS05905	COG0601	transmembrane transport
C7M16_RS05910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7M16_RS05915	COG0444	Belongs to the ABC transporter superfamily
C7M16_RS05920	COG4166	transmembrane transport
C7M16_RS05925	COG1619	proteins homologs of microcin C7 resistance protein MccF
C7M16_RS05930	COG4948	Mandelate Racemase Muconate Lactonizing
C7M16_RS05935	COG0791	NLP P60 protein
C7M16_RS05940	COG4608	Belongs to the ABC transporter superfamily
C7M16_RS05945	COG2706	6-phosphogluconolactonase activity
C7M16_RS05950	COG1834	amidinotransferase
C7M16_RS05955	COG1607	acyl-coa hydrolase
C7M16_RS05960	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C7M16_RS05960	COG1017	nitric oxide dioxygenase activity
C7M16_RS05970	COG2323	membrane
C7M16_RS05975	COG2318	DinB family
C7M16_RS05980	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M16_RS05985	COG2076	Multidrug Resistance protein
C7M16_RS05990	COG2076	Multidrug Resistance protein
C7M16_RS05995	COG0788	formyltetrahydrofolate deformylase activity
C7M16_RS06000	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C7M16_RS06005	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C7M16_RS06010	COG1764	response to oxidative stress
C7M16_RS06015	COG1846	Transcriptional regulator
C7M16_RS06020	COG1764	response to oxidative stress
C7M16_RS06030	COG0590	tRNA wobble adenosine to inosine editing
C7M16_RS06040	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7M16_RS06045	COG1404	Belongs to the peptidase S8 family
C7M16_RS06050	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M16_RS06055	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C7M16_RS06060	COG1122	ATPase activity
C7M16_RS06065	COG4721	ABC-type cobalt transport system, permease component
C7M16_RS06075	COG0745	RESPONSE REGULATOR receiver
C7M16_RS06080	COG3850	Histidine kinase
C7M16_RS06080	COG5002	protein histidine kinase activity
C7M16_RS06085	COG3212	peptidase
C7M16_RS06090	COG3212	peptidase
C7M16_RS06100	COG2239	Acts as a magnesium transporter
C7M16_RS06105	COG0789	Transcriptional regulator
C7M16_RS06120	COG1846	Transcriptional regulator
C7M16_RS06130	COG0726	polysaccharide deacetylase
C7M16_RS06135	COG1408	metallophosphoesterase
C7M16_RS06145	COG0463	Glycosyl transferase, family 2
C7M16_RS06150	COG1793	dna ligase
C7M16_RS06150	COG3285	dna ligase
C7M16_RS06155	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
C7M16_RS06165	COG0586	Pfam SNARE associated Golgi protein
C7M16_RS06170	COG0861	Integral membrane protein TerC family
C7M16_RS06175	COG1191	sigma factor activity
C7M16_RS06195	COG0501	Belongs to the peptidase M48B family
C7M16_RS06200	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7M16_RS06215	COG3594	Acyltransferase
C7M16_RS06220	COG5002	protein histidine kinase activity
C7M16_RS06225	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C7M16_RS06235	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
C7M16_RS06240	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
C7M16_RS06245	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7M16_RS06250	COG0436	Aminotransferase
C7M16_RS06255	COG1850	ribulose-bisphosphate carboxylase activity
C7M16_RS06260	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
C7M16_RS06265	COG0235	Class ii aldolase
C7M16_RS06270	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
C7M16_RS06275	COG3339	Conserved Protein
C7M16_RS06290	COG3852	Histidine kinase
C7M16_RS06295	COG1846	Transcriptional regulator
C7M16_RS06300	COG1360	Flagellar Motor Protein
C7M16_RS06305	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C7M16_RS06310	COG0542	response to heat
C7M16_RS06315	COG3949	Membrane
C7M16_RS06320	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
C7M16_RS06325	COG0720	synthase
C7M16_RS06330	COG0602	queuosine metabolic process
C7M16_RS06335	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
C7M16_RS06340	COG1733	regulation of RNA biosynthetic process
C7M16_RS06345	COG1028	Short-chain dehydrogenase reductase Sdr
C7M16_RS06350	COG1388	LysM domain
C7M16_RS06350	COG4641	Protein conserved in bacteria
C7M16_RS06355	COG1388	LysM domain
C7M16_RS06360	COG3858	chitin binding
C7M16_RS06370	COG4873	Protein conserved in bacteria
C7M16_RS06380	COG3773	Cell wall hydrolase
C7M16_RS06385	COG2244	polysaccharide biosynthetic process
C7M16_RS06390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M16_RS06395	COG2217	Heavy metal translocating P-type atpase
C7M16_RS06405	COG0006	proline dipeptidase activity
C7M16_RS06410	COG1609	Transcriptional regulator
C7M16_RS06415	COG3711	transcriptional antiterminator
C7M16_RS06420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M16_RS06420	COG1263	PTS System
C7M16_RS06420	COG2190	(PTS) system
C7M16_RS06425	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M16_RS06430	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C7M16_RS06440	COG1533	DNA photolyase activity
C7M16_RS06445	COG0456	acetyltransferase
C7M16_RS06450	COG0840	transmembrane signaling receptor activity
C7M16_RS06455	COG2084	Dehydrogenase
C7M16_RS06460	COG2340	Cysteine-rich secretory protein family
C7M16_RS06465	COG0768	penicillin binding
C7M16_RS06470	COG4191	Histidine kinase
C7M16_RS06475	COG0436	Aminotransferase
C7M16_RS06485	COG0784	Response regulator, receiver
C7M16_RS06485	COG0835	chemotaxis
C7M16_RS06495	COG2814	Major facilitator Superfamily
C7M16_RS06500	COG1376	ErfK ybiS ycfS ynhG family protein
C7M16_RS06505	COG1408	metallophosphoesterase
C7M16_RS06510	COG1028	Short-chain dehydrogenase reductase Sdr
C7M16_RS06515	COG2200	EAL domain
C7M16_RS06520	COG4703	Protein of unknown function (DUF1797)
C7M16_RS06525	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
C7M16_RS06535	COG0517	IMP dehydrogenase activity
C7M16_RS06540	COG0583	DNA-binding transcription factor activity
C7M16_RS06545	COG0716	FMN binding
C7M16_RS06555	COG0716	FMN binding
C7M16_RS06560	COG2171	N-acyltransferase activity
C7M16_RS06565	COG1473	amidohydrolase
C7M16_RS06575	COG0668	transmembrane transport
C7M16_RS06580	COG0450	alkyl hydroperoxide reductase
C7M16_RS06585	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M16_RS06600	COG0746	molybdenum cofactor guanylyltransferase activity
C7M16_RS06605	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C7M16_RS06610	COG0303	'Molybdopterin
C7M16_RS06615	COG1763	Mo-molybdopterin cofactor biosynthetic process
C7M16_RS06620	COG0314	molybdopterin synthase activity
C7M16_RS06625	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C7M16_RS06630	COG1132	(ABC) transporter
C7M16_RS06635	COG1132	(ABC) transporter
C7M16_RS06645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7M16_RS06650	COG1136	(ABC) transporter
C7M16_RS06655	COG0577	efflux transmembrane transporter activity
C7M16_RS06660	COG1349	DNA-binding transcription factor activity
C7M16_RS06665	COG1105	Belongs to the carbohydrate kinase PfkB family
C7M16_RS06670	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M16_RS06670	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M16_RS06670	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M16_RS06675	COG0681	Belongs to the peptidase S26 family
C7M16_RS06685	COG0488	(ABC) transporter
C7M16_RS06690	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C7M16_RS06695	COG2309	aminopeptidase activity
C7M16_RS06705	COG1077	Cell shape determining protein MreB Mrl
C7M16_RS06710	COG2002	toxin-antitoxin pair type II binding
C7M16_RS06715	COG3852	Histidine kinase
C7M16_RS06720	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
C7M16_RS06720	COG2105	PFAM AIG2 family protein
C7M16_RS06725	COG0569	domain protein
C7M16_RS06730	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C7M16_RS06735	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C7M16_RS06745	COG0561	phosphatase activity
C7M16_RS06750	COG0242	peptide deformylase activity
C7M16_RS06760	COG0497	DNA recombination
C7M16_RS06765	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C7M16_RS06770	COG0022	dehydrogenase e1 component
C7M16_RS06775	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7M16_RS06780	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7M16_RS06785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M16_RS06795	COG1982	Orn Lys Arg decarboxylase major
C7M16_RS06800	COG4476	Belongs to the UPF0223 family
C7M16_RS06805	COG4493	Belongs to the UPF0637 family
C7M16_RS06815	COG0483	inositol monophosphate 1-phosphatase activity
C7M16_RS06825	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
C7M16_RS06845	COG1595	DNA-templated transcription, initiation
C7M16_RS06875	COG4896	Protein conserved in bacteria
C7M16_RS06885	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C7M16_RS06890	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C7M16_RS06895	COG2066	Belongs to the glutaminase family
C7M16_RS06900	COG4838	Belongs to the UPF0358 family
C7M16_RS06905	COG0772	Belongs to the SEDS family
C7M16_RS06910	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
C7M16_RS06915	COG1612	heme a metabolic process
C7M16_RS06920	COG0109	protoheme IX farnesyltransferase activity
C7M16_RS06925	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C7M16_RS06925	COG2010	Cytochrome c
C7M16_RS06930	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C7M16_RS06935	COG1845	cytochrome c oxidase, subunit III
C7M16_RS06940	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C7M16_RS06945	COG3336	cytochrome c oxidase
C7M16_RS06955	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
C7M16_RS06960	COG2340	Cysteine-rich secretory protein family
C7M16_RS06975	COG3679	Belongs to the UPF0342 family
C7M16_RS06980	COG4471	UPF0298 protein
C7M16_RS06985	COG0742	ribosomal rna small subunit methyltransferase
C7M16_RS06990	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C7M16_RS06995	COG3314	Sporulation integral membrane protein YlbJ
C7M16_RS07000	COG1752	Esterase of the alpha-beta hydrolase superfamily
C7M16_RS07005	COG3480	Lon protease (S16) C-terminal proteolytic domain
C7M16_RS07010	COG1323	Belongs to the UPF0348 family
C7M16_RS07020	COG1399	metal-binding, possibly nucleic acid-binding protein
C7M16_RS07025	COG0333	Belongs to the bacterial ribosomal protein bL32 family
C7M16_RS07035	COG0454	-acetyltransferase
C7M16_RS07040	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C7M16_RS07045	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
C7M16_RS07050	COG2001	Belongs to the MraZ family
C7M16_RS07055	COG0275	rRNA processing
C7M16_RS07060	COG4839	cell division protein FtsL
C7M16_RS07070	COG0768	penicillin binding
C7M16_RS07075	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C7M16_RS07080	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C7M16_RS07085	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C7M16_RS07090	COG0772	Belongs to the SEDS family
C7M16_RS07095	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C7M16_RS07100	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C7M16_RS07105	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C7M16_RS07110	COG3879	Bacterial protein of unknown function (DUF881)
C7M16_RS07115	COG3879	Bacterial protein of unknown function (DUF881)
C7M16_RS07120	COG3856	small basic protein
C7M16_RS07125	COG0849	cell division
C7M16_RS07130	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C7M16_RS07135	COG1404	Belongs to the peptidase S8 family
C7M16_RS07135	COG4412	M6 family metalloprotease domain protein
C7M16_RS07145	COG1191	sigma factor activity
C7M16_RS07150	COG1191	sigma factor activity
C7M16_RS07155	COG1119	ATPase activity
C7M16_RS07160	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M16_RS07165	COG1873	PFAM PRC-barrel domain
C7M16_RS07175	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C7M16_RS07180	COG1799	cell septum assembly
C7M16_RS07185	COG0762	integral membrane protein
C7M16_RS07190	COG2302	S4 RNA-binding domain
C7M16_RS07195	COG3599	regulation of cell shape
C7M16_RS07200	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C7M16_RS07205	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C7M16_RS07210	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
C7M16_RS07215	COG0564	pseudouridine synthase activity
C7M16_RS07220	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
C7M16_RS07225	COG2233	PERMEase
C7M16_RS07230	COG0540	Belongs to the ATCase OTCase family
C7M16_RS07235	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C7M16_RS07240	COG0505	Belongs to the CarA family
C7M16_RS07245	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C7M16_RS07250	COG0543	2 iron, 2 sulfur cluster binding
C7M16_RS07255	COG0167	dihydroorotate dehydrogenase activity
C7M16_RS07260	COG0284	orotidine-5'-phosphate decarboxylase activity
C7M16_RS07265	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C7M16_RS07270	COG0175	sulfate reduction
C7M16_RS07275	COG0306	phosphate transporter
C7M16_RS07280	COG2046	Belongs to the sulfate adenylyltransferase family
C7M16_RS07285	COG0529	Catalyzes the synthesis of activated sulfate
C7M16_RS07290	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C7M16_RS07295	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
C7M16_RS07300	COG1648	precorrin-2 dehydrogenase activity
C7M16_RS07310	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C7M16_RS07315	COG1561	YicC-like family, N-terminal region
C7M16_RS07320	COG2052	Domain of unknown function (DUF370)
C7M16_RS07325	COG0194	GDP metabolic process
C7M16_RS07330	COG1758	RNA polymerase activity
C7M16_RS07335	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C7M16_RS07340	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C7M16_RS07345	COG0242	peptide deformylase activity
C7M16_RS07350	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C7M16_RS07355	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7M16_RS07355	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C7M16_RS07360	COG0820	rRNA (adenine-C2-)-methyltransferase activity
C7M16_RS07365	COG0631	protein serine/threonine phosphatase activity
C7M16_RS07370	COG0515	serine threonine protein kinase
C7M16_RS07370	COG2815	serine threonine protein kinase
C7M16_RS07375	COG1162	GTPase activity
C7M16_RS07380	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C7M16_RS07385	COG1564	THIamine pyrophosphokinase
C7M16_RS07395	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C7M16_RS07400	COG1302	Protein conserved in bacteria
C7M16_RS07405	COG1461	Dihydroxyacetone kinase
C7M16_RS07410	COG1760	l-serine dehydratase
C7M16_RS07415	COG1760	l-serine dehydratase
C7M16_RS07420	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C7M16_RS07425	COG2050	protein possibly involved in aromatic compounds catabolism
C7M16_RS07425	COG1349	DNA-binding transcription factor activity
C7M16_RS07430	COG0416	fatty acid biosynthetic process
C7M16_RS07435	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C7M16_RS07440	COG1028	Short-chain dehydrogenase reductase Sdr
C7M16_RS07445	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M16_RS07450	COG0571	ribonuclease III activity
C7M16_RS07455	COG1196	nuclear chromosome segregation
C7M16_RS07460	COG0552	protein localization to endoplasmic reticulum
C7M16_RS07470	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
C7M16_RS07475	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C7M16_RS07480	COG0228	four-way junction DNA binding
C7M16_RS07485	COG1837	Belongs to the UPF0109 family
C7M16_RS07495	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C7M16_RS07500	COG0336	Belongs to the RNA methyltransferase TrmD family
C7M16_RS07505	COG0335	large ribosomal subunit rRNA binding
C7M16_RS07510	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C7M16_RS07515	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C7M16_RS07525	COG2257	FlhB HrpN YscU SpaS Family
C7M16_RS07530	COG0045	succinate-CoA ligase (ADP-forming) activity
C7M16_RS07535	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C7M16_RS07540	COG0758	DNA mediated transformation
C7M16_RS07545	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C7M16_RS07550	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
C7M16_RS07555	COG4974	Belongs to the 'phage' integrase family
C7M16_RS07560	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
C7M16_RS07565	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
C7M16_RS07570	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
C7M16_RS07575	COG1815	bacterial-type flagellum-dependent cell motility
C7M16_RS07580	COG1558	bacterial-type flagellum-dependent cell motility
C7M16_RS07585	COG1677	Flagellar hook-basal body complex protein FliE
C7M16_RS07590	COG1766	The M ring may be actively involved in energy transduction
C7M16_RS07595	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C7M16_RS07600	COG1317	bacterial-type flagellum organization
C7M16_RS07605	COG1157	protein secretion by the type III secretion system
C7M16_RS07610	COG2882	bacterial-type flagellum organization
C7M16_RS07615	COG3334	PFAM MgtE intracellular
C7M16_RS07620	COG3144	bacterial-type flagellum assembly
C7M16_RS07625	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C7M16_RS07630	COG4786	Flagellar basal body rod
C7M16_RS07635	COG1582	Flagellar protein (FlbD)
C7M16_RS07640	COG1580	Controls the rotational direction of flagella during chemotaxis
C7M16_RS07645	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C7M16_RS07650	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C7M16_RS07650	COG1776	CheC inhibitor of MCP methylation
C7M16_RS07655	COG2201	protein-glutamate methylesterase activity
C7M16_RS07660	COG3190	flagellar
C7M16_RS07665	COG1338	Plays a role in the flagellum-specific transport system
C7M16_RS07670	COG1987	bacterial-type flagellum assembly
C7M16_RS07675	COG1684	flagellar biosynthetic protein fliR
C7M16_RS07680	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C7M16_RS07685	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C7M16_RS07690	COG1419	protein localization to endoplasmic reticulum
C7M16_RS07695	COG0455	bacterial-type flagellum organization
C7M16_RS07700	COG2201	protein-glutamate methylesterase activity
C7M16_RS07705	COG2198	Histidine kinase
C7M16_RS07705	COG0643	Histidine kinase
C7M16_RS07710	COG0835	chemotaxis
C7M16_RS07715	COG1776	CheC inhibitor of MCP methylation
C7M16_RS07720	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
C7M16_RS07725	COG1191	sigma factor activity
C7M16_RS07735	COG0052	Belongs to the universal ribosomal protein uS2 family
C7M16_RS07740	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
C7M16_RS07745	COG0528	UMP kinase activity
C7M16_RS07750	COG0233	cytoplasmic translational termination
C7M16_RS07755	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C7M16_RS07760	COG4589	Belongs to the CDS family
C7M16_RS07765	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C7M16_RS07770	COG0750	zinc metalloprotease
C7M16_RS07775	COG0442	prolyl-tRNA aminoacylation
C7M16_RS07780	COG2176	DNA-directed DNA polymerase activity
C7M16_RS07785	COG0779	Required for maturation of 30S ribosomal subunits
C7M16_RS07790	COG0195	Participates in both transcription termination and antitermination
C7M16_RS07795	COG2740	Nucleic-acid-binding protein implicated in transcription termination
C7M16_RS07800	COG1358	cellular component organization or biogenesis
C7M16_RS07805	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
C7M16_RS07810	COG1550	Protein conserved in bacteria
C7M16_RS07815	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C7M16_RS07820	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C7M16_RS07825	COG0196	riboflavin kinase activity
C7M16_RS07830	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C7M16_RS07835	COG1185	polyribonucleotide nucleotidyltransferase activity
C7M16_RS07840	COG0726	polysaccharide deacetylase
C7M16_RS07845	COG0612	Peptidase, M16
C7M16_RS07850	COG1873	PFAM PRC-barrel domain
C7M16_RS07855	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7M16_RS07860	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C7M16_RS07865	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C7M16_RS07870	COG0527	aspartate kinase activity
C7M16_RS07875	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C7M16_RS07880	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C7M16_RS07885	COG0740	serine-type endopeptidase activity
C7M16_RS07895	COG1674	ftsk spoiiie
C7M16_RS07895	COG4980	gas vesicle protein
C7M16_RS07900	COG2188	Transcriptional regulator
C7M16_RS07905	COG2814	Major facilitator Superfamily
C7M16_RS07910	COG0612	Peptidase, M16
C7M16_RS07915	COG0612	Peptidase, M16
C7M16_RS07920	COG0300	oxidoreductase activity
C7M16_RS07935	COG1426	Protein conserved in bacteria
C7M16_RS07940	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C7M16_RS07945	COG1546	Belongs to the CinA family
C7M16_RS07945	COG1058	Belongs to the CinA family
C7M16_RS07950	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C7M16_RS07955	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M16_RS07960	COG1418	mRNA catabolic process
C7M16_RS07965	COG1692	metallophosphoesterase
C7M16_RS07970	COG2359	stage V sporulation protein S
C7M16_RS07975	COG1063	alcohol dehydrogenase
C7M16_RS07980	COG0156	8-amino-7-oxononanoate synthase activity
C7M16_RS07985	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C7M16_RS07990	COG4550	Control of competence regulator ComK, YlbF/YmcA
C7M16_RS08000	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
C7M16_RS08005	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C7M16_RS08020	COG3226	Transcriptional regulator
C7M16_RS08025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M16_RS08035	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C7M16_RS08040	COG3321	synthase
C7M16_RS08045	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C7M16_RS08045	COG2070	2-Nitropropane dioxygenase
C7M16_RS08050	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M16_RS08055	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C7M16_RS08060	COG3425	synthase
C7M16_RS08065	COG1024	Enoyl-CoA hydratase
C7M16_RS08070	COG1024	Enoyl-CoA hydratase
C7M16_RS08075	COG0300	oxidoreductase activity
C7M16_RS08075	COG0318	PFAM AMP-dependent synthetase and ligase
C7M16_RS08075	COG3321	synthase
C7M16_RS08075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M16_RS08075	COG1028	Short-chain dehydrogenase reductase Sdr
C7M16_RS08080	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M16_RS08080	COG0300	oxidoreductase activity
C7M16_RS08080	COG3321	synthase
C7M16_RS08080	COG4221	oxidoreductase activity
C7M16_RS08085	COG3321	synthase
C7M16_RS08085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M16_RS08085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M16_RS08085	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M16_RS08085	COG1028	Short-chain dehydrogenase reductase Sdr
C7M16_RS08090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M16_RS08090	COG3321	synthase
C7M16_RS08090	COG1028	Short-chain dehydrogenase reductase Sdr
C7M16_RS08090	COG4221	oxidoreductase activity
C7M16_RS08095	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C7M16_RS08095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M16_RS08095	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
C7M16_RS08095	COG3321	synthase
C7M16_RS08100	COG2124	cytochrome p450
C7M16_RS08110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M16_RS08115	COG1404	Belongs to the peptidase S8 family
C7M16_RS08125	COG4195	phage-related replication protein
C7M16_RS08130	COG1764	response to oxidative stress
C7M16_RS08135	COG2076	Multidrug Resistance protein
C7M16_RS08140	COG2076	Multidrug Resistance protein
C7M16_RS08155	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
C7M16_RS08160	COG1923	regulation of RNA biosynthetic process
C7M16_RS08175	COG1780	Probably involved in ribonucleotide reductase function
C7M16_RS08180	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7M16_RS08185	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7M16_RS08190	COG4112	unkown
C7M16_RS08195	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M16_RS08200	COG0464	growth
C7M16_RS08205	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C7M16_RS08210	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
C7M16_RS08215	COG0789	Transcriptional regulator
C7M16_RS08220	COG0174	glutamine synthetase
C7M16_RS08255	COG0463	Glycosyl transferase, family 2
C7M16_RS08270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M16_RS08285	COG3655	Transcriptional regulator
C7M16_RS08300	COG0135	phosphoribosylanthranilate isomerase activity
C7M16_RS08305	COG2211	Major facilitator Superfamily
C7M16_RS08310	COG3507	Belongs to the glycosyl hydrolase 43 family
C7M16_RS08315	COG1940	carbohydrate kinase activity
C7M16_RS08320	COG2115	Belongs to the xylose isomerase family
C7M16_RS08325	COG1070	Carbohydrate kinase
C7M16_RS08335	COG1525	nuclease
C7M16_RS08340	COG2814	Major facilitator Superfamily
C7M16_RS08345	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C7M16_RS08355	COG0756	dUTP diphosphatase activity
C7M16_RS08400	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C7M16_RS08410	COG3832	glyoxalase III activity
C7M16_RS08420	COG0697	spore germination
C7M16_RS08425	COG0531	amino acid
C7M16_RS08455	COG4195	phage-related replication protein
C7M16_RS08465	COG0346	lactoylglutathione lyase activity
C7M16_RS08470	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C7M16_RS08475	COG1388	LysM domain
C7M16_RS08480	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C7M16_RS08485	COG4224	UPF0291 protein
C7M16_RS08490	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C7M16_RS08500	COG3763	UPF0154 protein
C7M16_RS08510	COG0785	Cytochrome C biogenesis protein
C7M16_RS08515	COG2201	protein-glutamate methylesterase activity
C7M16_RS08520	COG4846	Membrane protein involved in cytochrome C biogenesis
C7M16_RS08530	COG0071	Belongs to the small heat shock protein (HSP20) family
C7M16_RS08545	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C7M16_RS08550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M16_RS08570	COG0824	Thioesterase
C7M16_RS08580	COG4841	protein insertion into membrane
C7M16_RS08585	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
C7M16_RS08590	COG1832	CoA-binding protein
C7M16_RS08595	COG0187	DNA topoisomerase II activity
C7M16_RS08600	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C7M16_RS08610	COG1115	amino acid carrier protein
C7M16_RS08615	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
C7M16_RS08625	COG5520	Belongs to the glycosyl hydrolase 30 family
C7M16_RS08630	COG3507	Belongs to the glycosyl hydrolase 43 family
C7M16_RS08635	COG2246	polysaccharide biosynthetic process
C7M16_RS08640	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7M16_RS08645	COG0586	Pfam SNARE associated Golgi protein
C7M16_RS08650	COG2404	hydrolase activity, acting on ester bonds
C7M16_RS08655	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C7M16_RS08660	COG1024	Enoyl-CoA hydratase
C7M16_RS08665	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C7M16_RS08670	COG0511	ligase activity, forming carbon-carbon bonds
C7M16_RS08675	COG0439	Biotin carboxylase
C7M16_RS08680	COG0318	PFAM AMP-dependent synthetase and ligase
C7M16_RS08685	COG1960	acyl-CoA dehydrogenase activity
C7M16_RS08700	COG1649	PFAM Uncharacterised BCR, COG1649
C7M16_RS08710	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M16_RS08710	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
C7M16_RS08715	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M16_RS08720	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M16_RS08725	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M16_RS08730	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M16_RS08735	COG2027	D-alanyl-D-alanine carboxypeptidase
C7M16_RS08740	COG2017	converts alpha-aldose to the beta-anomer
C7M16_RS08745	COG0534	Mate efflux family protein
C7M16_RS08760	COG0582	viral genome integration into host DNA
C7M16_RS08765	COG0166	Belongs to the GPI family
C7M16_RS08770	COG0405	Gamma-glutamyltransferase
C7M16_RS08775	COG0583	DNA-binding transcription factor activity
C7M16_RS08780	COG0604	alcohol dehydrogenase
C7M16_RS08785	COG0493	'glutamate synthase
C7M16_RS08790	COG0067	glutamate synthase
C7M16_RS08790	COG0069	glutamate synthase activity
C7M16_RS08790	COG0070	glutamate synthase
C7M16_RS08795	COG0583	DNA-binding transcription factor activity
C7M16_RS08800	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C7M16_RS08805	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7M16_RS08815	COG0300	oxidoreductase activity
C7M16_RS08820	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
C7M16_RS08830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M16_RS08835	COG2814	Major facilitator Superfamily
C7M16_RS08840	COG1070	Carbohydrate kinase
C7M16_RS08845	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C7M16_RS08850	COG0243	molybdopterin cofactor binding
C7M16_RS08880	COG0840	transmembrane signaling receptor activity
C7M16_RS08880	COG5278	phosphoserine phosphatase activity
C7M16_RS08885	COG2368	4-hydroxyphenylacetate
C7M16_RS08890	COG4305	rare lipoprotein A
C7M16_RS08895	COG3619	membrane
C7M16_RS08900	COG3866	Pectate lyase
C7M16_RS08905	COG2135	peptidase activity
C7M16_RS08915	COG2140	Oxalate decarboxylase
C7M16_RS08925	COG0456	acetyltransferase
C7M16_RS08945	COG2720	vancomycin resistance protein
C7M16_RS08955	COG3655	Transcriptional regulator
C7M16_RS08960	COG3739	integral membrane protein
C7M16_RS08965	COG0583	DNA-binding transcription factor activity
C7M16_RS08970	COG0697	spore germination
C7M16_RS08980	COG0693	protein deglycase activity
C7M16_RS08985	COG2367	Beta-lactamase
C7M16_RS09005	COG3848	Pyruvate phosphate dikinase
C7M16_RS09005	COG0574	Belongs to the PEP-utilizing enzyme family
C7M16_RS09010	COG0726	polysaccharide deacetylase
C7M16_RS09015	COG2314	TM2 domain
C7M16_RS09070	COG0457	Tetratricopeptide repeat
C7M16_RS09085	COG4282	regulation of fungal-type cell wall biogenesis
C7M16_RS09090	COG1231	oxidoreductase activity
C7M16_RS09095	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M16_RS09100	COG2207	Transcriptional regulator
C7M16_RS09100	COG0662	Cupin 2, conserved barrel domain protein
C7M16_RS09105	COG0456	acetyltransferase
C7M16_RS09110	COG1309	transcriptional regulator
C7M16_RS09115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M16_RS09120	COG3708	Transcriptional regulator
C7M16_RS09125	COG2378	regulation of single-species biofilm formation
C7M16_RS09135	COG0640	Transcriptional regulator
C7M16_RS09140	COG0741	lytic transglycosylase activity
C7M16_RS09145	COG2322	membrane
C7M16_RS09160	COG1619	proteins homologs of microcin C7 resistance protein MccF
C7M16_RS09165	COG3239	Fatty acid desaturase
C7M16_RS09170	COG4585	Histidine kinase
C7M16_RS09175	COG2197	response regulator
C7M16_RS09180	COG1388	LysM domain
C7M16_RS09180	COG3584	3D domain protein
C7M16_RS09185	COG0514	ATP-dependent DNA helicase (RecQ)
C7M16_RS09195	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C7M16_RS09200	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C7M16_RS09215	COG0071	Belongs to the small heat shock protein (HSP20) family
C7M16_RS09240	COG1012	belongs to the aldehyde dehydrogenase family
C7M16_RS09245	COG1657	PFAM Prenyltransferase squalene oxidase
C7M16_RS09250	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C7M16_RS09255	COG0733	neurotransmitter:sodium symporter activity
C7M16_RS09260	COG0385	Bile acid
C7M16_RS09265	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7M16_RS09270	COG0567	Dehydrogenase, E1 component
C7M16_RS09275	COG4548	von Willebrand factor, type A
C7M16_RS09280	COG0714	Associated with various cellular activities
C7M16_RS09285	COG2032	superoxide dismutase activity
C7M16_RS09290	COG0791	NLP P60 protein
C7M16_RS09290	COG1388	LysM domain
C7M16_RS09295	COG1819	glycosyl
C7M16_RS09300	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C7M16_RS09305	COG0534	Mate efflux family protein
C7M16_RS09310	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M16_RS09315	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C7M16_RS09320	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C7M16_RS09330	COG2962	Rard protein
C7M16_RS09345	COG2610	gluconate transmembrane transporter activity
C7M16_RS09350	COG1942	4-Oxalocrotonate Tautomerase
C7M16_RS09355	COG1733	regulation of RNA biosynthetic process
C7M16_RS09360	COG0778	Nitroreductase
C7M16_RS09365	COG0400	carboxylic ester hydrolase activity
C7M16_RS09370	COG0346	lactoylglutathione lyase activity
C7M16_RS09380	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M16_RS09385	COG3409	Peptidoglycan-binding domain 1 protein
C7M16_RS09385	COG0793	Belongs to the peptidase S41A family
C7M16_RS09390	COG2226	methyltransferase
C7M16_RS09400	COG1876	peptidase activity
C7M16_RS09405	COG0813	purine-nucleoside phosphorylase activity
C7M16_RS09420	COG0671	phosphoesterase, PA-phosphatase related
C7M16_RS09440	COG4479	Belongs to the UPF0346 family
C7M16_RS09450	COG1509	lysine 2,3-aminomutase activity
C7M16_RS09455	COG0456	acetyltransferase
C7M16_RS09460	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M16_RS09465	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C7M16_RS09470	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C7M16_RS09475	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C7M16_RS09490	COG0456	acetyltransferase
C7M16_RS09495	COG0463	Glycosyl transferase, family 2
C7M16_RS09510	COG4641	Protein conserved in bacteria
C7M16_RS09515	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
C7M16_RS09520	COG1086	Polysaccharide biosynthesis protein
C7M16_RS09525	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C7M16_RS09530	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C7M16_RS09535	COG1846	Transcriptional regulator
C7M16_RS09540	COG0534	Mate efflux family protein
C7M16_RS09550	COG4698	Protein conserved in bacteria
C7M16_RS09555	COG2755	lipolytic protein G-D-S-L family
C7M16_RS09560	COG1999	signal sequence binding
C7M16_RS09570	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C7M16_RS09575	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C7M16_RS09580	COG1272	protein, Hemolysin III
C7M16_RS09585	COG0204	Acyl-transferase
C7M16_RS09590	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C7M16_RS09595	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
C7M16_RS09600	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C7M16_RS09610	COG2521	methyltransferase
C7M16_RS09610	COG2136	Putative SAM-dependent methyltransferase
C7M16_RS09620	COG0129	dihydroxy-acid dehydratase activity
C7M16_RS09625	COG1413	lyase activity
C7M16_RS09630	COG1418	mRNA catabolic process
C7M16_RS09635	COG0386	Belongs to the glutathione peroxidase family
C7M16_RS09640	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
C7M16_RS09645	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C7M16_RS09655	COG1278	Cold shock
C7M16_RS09675	COG0328	RNA-DNA hybrid ribonuclease activity
C7M16_RS09680	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C7M16_RS09685	COG0328	RNA-DNA hybrid ribonuclease activity
C7M16_RS09695	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7M16_RS09710	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C7M16_RS09720	COG1755	Isoprenylcysteine carboxyl methyltransferase
C7M16_RS09725	COG3424	synthase
C7M16_RS09730	COG2233	PERMEase
C7M16_RS09735	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7M16_RS09740	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
C7M16_RS09750	COG0800	Aldolase
C7M16_RS09755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7M16_RS09760	COG1609	Transcriptional regulator
C7M16_RS09765	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
C7M16_RS09770	COG1028	Short-chain dehydrogenase reductase Sdr
C7M16_RS09775	COG1199	ATP-dependent helicase activity
C7M16_RS09795	COG0116	Belongs to the methyltransferase superfamily
C7M16_RS09810	COG4474	Belongs to the UPF0398 family
C7M16_RS09825	COG3359	exonuclease
C7M16_RS09830	COG1111	helicase
C7M16_RS09830	COG1205	dead DEAH box helicase
C7M16_RS09835	COG2190	(PTS) system
C7M16_RS09840	COG0071	Belongs to the small heat shock protein (HSP20) family
C7M16_RS09875	COG3331	DNA recombination
C7M16_RS09880	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7M16_RS09880	COG4499	WXG100 protein secretion system (Wss), protein YukC
C7M16_RS09890	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C7M16_RS09895	COG3935	DnaD domain protein
C7M16_RS09900	COG0017	Asparaginyl-tRNA synthetase
C7M16_RS09905	COG0436	Aminotransferase
C7M16_RS09910	COG5353	protein conserved in bacteria
C7M16_RS09920	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C7M16_RS09920	COG1199	ATP-dependent helicase activity
C7M16_RS09925	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
C7M16_RS09930	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
C7M16_RS09935	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
C7M16_RS09940	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
C7M16_RS09940	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
C7M16_RS09945	COG0617	tRNA 3'-terminal CCA addition
C7M16_RS09950	COG0438	transferase activity, transferring glycosyl groups
C7M16_RS09955	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C7M16_RS09960	COG1803	Methylglyoxal synthase
C7M16_RS09965	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C7M16_RS09970	COG1694	Mazg nucleotide pyrophosphohydrolase
C7M16_RS09975	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M16_RS09985	COG4347	Protein of unknown function (DUF1405)
C7M16_RS09990	COG2010	Cytochrome c
C7M16_RS09990	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C7M16_RS09995	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C7M16_RS10000	COG0723	plastoquinol--plastocyanin reductase activity
C7M16_RS10010	COG5582	Belongs to the UPF0302 family
C7M16_RS10015	COG0457	Tetratricopeptide repeat
C7M16_RS10020	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C7M16_RS10025	COG0287	Prephenate dehydrogenase
C7M16_RS10035	COG0159	tryptophan synthase activity
C7M16_RS10040	COG0133	tryptophan synthase activity
C7M16_RS10045	COG0135	phosphoribosylanthranilate isomerase activity
C7M16_RS10055	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C7M16_RS10060	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C7M16_RS10065	COG4401	Chorismate mutase type I
C7M16_RS10070	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
C7M16_RS10075	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
C7M16_RS10080	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C7M16_RS10085	COG0105	UTP biosynthetic process
C7M16_RS10090	COG0142	geranyltranstransferase activity
C7M16_RS10095	COG2226	methyltransferase
C7M16_RS10100	COG0142	geranyltranstransferase activity
C7M16_RS10110	COG0302	gtp cyclohydrolase
C7M16_RS10115	COG0776	regulation of translation
C7M16_RS10120	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C7M16_RS10135	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
C7M16_RS10140	COG1160	GTP binding
C7M16_RS10165	COG1304	FMN binding
C7M16_RS10170	COG0539	negative regulation of cytoplasmic translation
C7M16_RS10175	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C7M16_RS10185	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
C7M16_RS10190	COG2959	enzyme of heme biosynthesis
C7M16_RS10195	COG3409	Peptidoglycan-binding domain 1 protein
C7M16_RS10195	COG3773	Cell wall hydrolase
C7M16_RS10200	COG2339	peptidase activity
C7M16_RS10205	COG0492	ferredoxin-NADP+ reductase activity
C7M16_RS10210	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C7M16_RS10215	COG4862	establishment of competence for transformation
C7M16_RS10220	COG1408	metallophosphoesterase
C7M16_RS10230	COG1388	LysM domain
C7M16_RS10235	COG1266	CAAX protease self-immunity
C7M16_RS10240	COG0514	ATP-dependent DNA helicase (RecQ)
C7M16_RS10245	COG4955	Helix-turn-helix domain
C7M16_RS10250	COG1141	Ferredoxin
C7M16_RS10255	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
C7M16_RS10260	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C7M16_RS10265	COG0710	3-dehydroquinate dehydratase activity
C7M16_RS10275	COG1595	DNA-templated transcription, initiation
C7M16_RS10280	COG5002	protein histidine kinase activity
C7M16_RS10285	COG0745	RESPONSE REGULATOR receiver
C7M16_RS10290	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C7M16_RS10295	COG1333	cytochrome c biogenesis protein
C7M16_RS10300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M16_RS10305	COG1187	pseudouridine synthase activity
C7M16_RS10310	COG0700	Nucleoside recognition
C7M16_RS10315	COG2715	membrane protein required for spore maturation
C7M16_RS10320	COG1686	Belongs to the peptidase S11 family
C7M16_RS10330	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C7M16_RS10335	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C7M16_RS10340	COG1547	Domain of unknown function (DUF309)
C7M16_RS10345	COG0456	acetyltransferase
C7M16_RS10350	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
C7M16_RS10355	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C7M16_RS10355	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C7M16_RS10360	COG0307	riboflavin synthase, alpha
C7M16_RS10365	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7M16_RS10365	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7M16_RS10375	COG0681	Belongs to the peptidase S26 family
C7M16_RS10425	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C7M16_RS10430	COG4086	secreted protein
C7M16_RS10435	COG0019	diaminopimelate decarboxylase activity
C7M16_RS10440	COG0697	spore germination
C7M16_RS10455	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7M16_RS10475	COG1191	sigma factor activity
C7M16_RS10480	COG2172	sigma factor antagonist activity
C7M16_RS10485	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M16_RS10490	COG1686	Belongs to the peptidase S11 family
C7M16_RS10495	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
C7M16_RS10500	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
C7M16_RS10505	COG4974	Belongs to the 'phage' integrase family
C7M16_RS10515	COG0735	belongs to the Fur family
C7M16_RS10520	COG1300	Membrane
C7M16_RS10530	COG0281	malic enzyme
C7M16_RS10535	COG1757	Na H antiporter
C7M16_RS10540	COG1027	Aspartate ammonia-lyase
C7M16_RS10545	COG0252	asparaginase activity
C7M16_RS10550	COG1396	sequence-specific DNA binding
C7M16_RS10555	COG1379	DNA repair
C7M16_RS10560	COG0494	nUDIX hydrolase
C7M16_RS10570	COG0667	Aldo Keto reductase
C7M16_RS10580	COG1073	alpha beta
C7M16_RS10590	COG4918	Iron-sulphur cluster biosynthesis
C7M16_RS10595	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C7M16_RS10595	COG0456	acetyltransferase
C7M16_RS10600	COG2329	Antibiotic biosynthesis monooxygenase
C7M16_RS10605	COG0456	acetyltransferase
C7M16_RS10615	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7M16_RS10625	COG2211	Major facilitator Superfamily
C7M16_RS10630	COG0346	lactoylglutathione lyase activity
C7M16_RS10635	COG1072	(Pantothenic acid kinase))
C7M16_RS10640	COG3048	D-serine ammonia-lyase activity
C7M16_RS10645	COG0300	oxidoreductase activity
C7M16_RS10650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M16_RS10655	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7M16_RS10660	COG4187	Peptidase family M20/M25/M40
C7M16_RS10665	COG1902	pentaerythritol trinitrate reductase activity
C7M16_RS10670	COG0596	Alpha beta hydrolase
C7M16_RS10680	COG1234	tRNA 3'-trailer cleavage
C7M16_RS10685	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C7M16_RS10690	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C7M16_RS10695	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7M16_RS10705	COG0706	membrane insertase activity
C7M16_RS10730	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M16_RS10735	COG1028	Short-chain dehydrogenase reductase Sdr
C7M16_RS10740	COG2986	histidine ammonia-lyase
C7M16_RS10750	COG0109	protoheme IX farnesyltransferase activity
C7M16_RS10755	COG3361	conserved protein (COG2071)
C7M16_RS10760	COG2195	Cleaves the N-terminal amino acid of tripeptides
C7M16_RS10765	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C7M16_RS10770	COG0346	lactoylglutathione lyase activity
C7M16_RS10780	COG1376	ErfK ybiS ycfS ynhG family protein
C7M16_RS10785	COG4129	membrane
C7M16_RS10790	COG1126	abc transporter atp-binding protein
C7M16_RS10795	COG0765	amino acid transport
C7M16_RS10800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M16_RS10810	COG1597	lipid kinase activity
C7M16_RS10815	COG2814	Major facilitator Superfamily
C7M16_RS10820	COG4978	Transcriptional regulator
C7M16_RS10820	COG0789	Transcriptional regulator
C7M16_RS10825	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7M16_RS10830	COG0022	dehydrogenase e1 component
C7M16_RS10835	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C7M16_RS10840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7M16_RS10845	COG3426	butyrate kinase activity
C7M16_RS10850	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C7M16_RS10855	COG0280	phosphate acetyltransferase
C7M16_RS10860	COG3829	transcription factor binding
C7M16_RS10860	COG3290	protein histidine kinase activity
C7M16_RS10870	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C7M16_RS10875	COG2079	MmgE PrpD family protein
C7M16_RS10880	COG0372	Belongs to the citrate synthase family
C7M16_RS10885	COG1960	acyl-CoA dehydrogenase activity
C7M16_RS10890	COG1250	3-hydroxyacyl-CoA dehydrogenase
C7M16_RS10895	COG0183	Belongs to the thiolase family
C7M16_RS10900	COG0584	glycerophosphoryl diester phosphodiesterase
C7M16_RS10905	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M16_RS10920	COG1902	pentaerythritol trinitrate reductase activity
C7M16_RS10925	COG0745	RESPONSE REGULATOR receiver
C7M16_RS10930	COG0750	zinc metalloprotease
C7M16_RS10935	COG0497	DNA recombination
C7M16_RS10940	COG1438	arginine binding
C7M16_RS10945	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
C7M16_RS10950	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C7M16_RS10955	COG0142	geranyltranstransferase activity
C7M16_RS10960	COG1722	exodeoxyribonuclease VII activity
C7M16_RS10965	COG1570	exodeoxyribonuclease VII activity
C7M16_RS10970	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C7M16_RS10975	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7M16_RS10980	COG1302	Protein conserved in bacteria
C7M16_RS10985	COG0439	Biotin carboxylase
C7M16_RS10990	COG0511	ligase activity, forming carbon-carbon bonds
C7M16_RS11030	COG3854	ATPases associated with a variety of cellular activities
C7M16_RS11040	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C7M16_RS11045	COG0006	proline dipeptidase activity
C7M16_RS11050	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
C7M16_RS11060	COG3872	metal-dependent enzyme
C7M16_RS11070	COG1752	Esterase of the alpha-beta hydrolase superfamily
C7M16_RS11075	COG1321	iron dependent repressor
C7M16_RS11080	COG0095	Lipoate-protein ligase
C7M16_RS11085	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7M16_RS11090	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C7M16_RS11095	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C7M16_RS11100	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C7M16_RS11105	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C7M16_RS11120	COG1396	sequence-specific DNA binding
C7M16_RS11130	COG0681	Belongs to the peptidase S26 family
C7M16_RS11155	COG4940	Competence protein ComGF
C7M16_RS11165	COG4970	Tfp pilus assembly protein FimT
C7M16_RS11170	COG4537	Required for transformation and DNA binding
C7M16_RS11175	COG1459	type II secretion system
C7M16_RS11180	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C7M16_RS11185	COG0517	IMP dehydrogenase activity
C7M16_RS11190	COG0598	Magnesium transport protein CorA
C7M16_RS11195	COG1253	flavin adenine dinucleotide binding
C7M16_RS11200	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M16_RS11210	COG1393	Belongs to the ArsC family
C7M16_RS11220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M16_RS11230	COG0011	TIGRFAM Protein of
C7M16_RS11240	COG2866	Carboxypeptidase
C7M16_RS11245	COG1368	sulfuric ester hydrolase activity
C7M16_RS11250	COG1940	carbohydrate kinase activity
C7M16_RS11255	COG4483	Protein conserved in bacteria
C7M16_RS11260	COG0705	Rhomboid family
C7M16_RS11260	COG0457	Tetratricopeptide repeat
C7M16_RS11270	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C7M16_RS11275	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C7M16_RS11280	COG0438	transferase activity, transferring glycosyl groups
C7M16_RS11295	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C7M16_RS11300	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7M16_RS11305	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7M16_RS11310	COG0581	inorganic phosphate transmembrane transporter activity
C7M16_RS11315	COG0573	inorganic phosphate transmembrane transporter activity
C7M16_RS11320	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C7M16_RS11330	COG0477	Major facilitator Superfamily
C7M16_RS11335	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C7M16_RS11340	COG2839	Protein conserved in bacteria
C7M16_RS11345	COG5521	maltodextrose utilization protein MalA
C7M16_RS11355	COG1388	LysM domain
C7M16_RS11360	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
C7M16_RS11365	COG4709	membrane
C7M16_RS11370	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
C7M16_RS11375	COG0735	belongs to the Fur family
C7M16_RS11380	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M16_RS11390	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
C7M16_RS11395	COG0513	Belongs to the DEAD box helicase family
C7M16_RS11405	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
C7M16_RS11410	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C7M16_RS11415	COG2384	SAM-dependent methyltransferase
C7M16_RS11420	COG2010	Cytochrome c
C7M16_RS11425	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C7M16_RS11430	COG0358	DNA primase activity
C7M16_RS11435	COG1671	Belongs to the UPF0178 family
C7M16_RS11440	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
C7M16_RS11445	COG0517	IMP dehydrogenase activity
C7M16_RS11450	COG0751	glycine-tRNA ligase activity
C7M16_RS11455	COG0752	glycyl-tRNA synthetase alpha subunit
C7M16_RS11460	COG1381	Involved in DNA repair and RecF pathway recombination
C7M16_RS11470	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C7M16_RS11475	COG0295	cytidine deaminase activity
C7M16_RS11480	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C7M16_RS11485	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
C7M16_RS11490	COG1480	7TM receptor with intracellular HD hydrolase
C7M16_RS11495	COG1702	phosphate starvation-inducible protein PhoH
C7M16_RS11500	COG0561	phosphatase activity
C7M16_RS11515	COG4864	UPF0365 protein
C7M16_RS11520	COG1030	water channel activity
C7M16_RS11525	COG1610	YqeY-like protein
C7M16_RS11530	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C7M16_RS11535	COG1283	sodium-dependent phosphate transmembrane transporter activity
C7M16_RS11540	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C7M16_RS11545	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C7M16_RS11550	COG2264	protein methyltransferase activity
C7M16_RS11555	COG0484	heat shock protein binding
C7M16_RS11560	COG0443	Heat shock 70 kDa protein
C7M16_RS11565	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C7M16_RS11570	COG1420	regulation of RNA biosynthetic process
C7M16_RS11575	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C7M16_RS11580	COG0481	GTPase activity
C7M16_RS11590	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M16_RS11595	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C7M16_RS11600	COG0268	Binds directly to 16S ribosomal RNA
C7M16_RS11605	COG1466	dna polymerase III delta subunit
C7M16_RS11620	COG2333	competence protein COMEC
C7M16_RS11620	COG0658	competence protein
C7M16_RS11625	COG2131	deaminase
C7M16_RS11630	COG1596	polysaccharide export
C7M16_RS11630	COG1555	photosystem II stabilization
C7M16_RS11635	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7M16_RS11640	COG2226	methyltransferase
C7M16_RS11645	COG0799	negative regulation of ribosome biogenesis
C7M16_RS11650	COG1713	HD superfamily hydrolase involved in NAD metabolism
C7M16_RS11655	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C7M16_RS11660	COG1534	Rna-binding protein
C7M16_RS11665	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C7M16_RS11670	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C7M16_RS11675	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
C7M16_RS11685	COG2755	lipolytic protein G-D-S-L family
C7M16_RS11690	COG3409	Peptidoglycan-binding domain 1 protein
C7M16_RS11690	COG5632	N-Acetylmuramoyl-L-alanine amidase
C7M16_RS11695	COG0398	Pfam SNARE associated Golgi protein
C7M16_RS11700	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
C7M16_RS11710	COG3209	COG3209 Rhs family protein
C7M16_RS11730	COG4124	Belongs to the glycosyl hydrolase 26 family
C7M16_RS11735	COG0730	response to heat
C7M16_RS11740	COG0425	Belongs to the sulfur carrier protein TusA family
C7M16_RS11745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M16_RS11745	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7M16_RS11755	COG0425	Belongs to the sulfur carrier protein TusA family
C7M16_RS11755	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7M16_RS11765	COG2210	Belongs to the sulfur carrier protein TusA family
C7M16_RS11770	COG1937	Protein conserved in bacteria
C7M16_RS11775	COG0662	Cupin 2, conserved barrel domain protein
C7M16_RS11790	COG4978	Transcriptional regulator
C7M16_RS11790	COG0789	Transcriptional regulator
C7M16_RS11795	COG2814	Major facilitator Superfamily
C7M16_RS11800	COG0456	acetyltransferase
C7M16_RS11805	COG1253	flavin adenine dinucleotide binding
C7M16_RS11815	COG0697	spore germination
C7M16_RS11820	COG0583	DNA-binding transcription factor activity
C7M16_RS11825	COG2072	flavoprotein involved in K transport
C7M16_RS11830	COG1230	cation diffusion facilitator family transporter
C7M16_RS11835	COG1114	Component of the transport system for branched-chain amino acids
C7M16_RS11840	COG1687	branched-chain amino acid
C7M16_RS11845	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
C7M16_RS11850	COG1522	sequence-specific DNA binding
C7M16_RS11860	COG2124	cytochrome p450
C7M16_RS11865	COG1335	isochorismatase
C7M16_RS11880	COG2318	DinB family
C7M16_RS11890	COG2070	2-Nitropropane dioxygenase
C7M16_RS11910	COG3443	Belongs to the bacterial solute-binding protein 9 family
C7M16_RS11915	COG1595	DNA-templated transcription, initiation
C7M16_RS11920	COG0667	Aldo Keto reductase
C7M16_RS11925	COG2851	Citrate transporter
C7M16_RS11930	COG0583	DNA-binding transcription factor activity
C7M16_RS11935	COG2828	Protein conserved in bacteria
C7M16_RS11940	COG3409	Peptidoglycan-binding domain 1 protein
C7M16_RS11945	COG5566	PFAM Mor transcription activator
C7M16_RS11950	COG0596	Alpha beta hydrolase
C7M16_RS11955	COG4991	sh3 domain protein
C7M16_RS11960	COG4991	sh3 domain protein
C7M16_RS11965	COG0346	lactoylglutathione lyase activity
C7M16_RS11975	COG5577	PFAM Coat F domain
C7M16_RS11980	COG1063	alcohol dehydrogenase
C7M16_RS11990	COG5577	PFAM Coat F domain
C7M16_RS11995	COG0789	Transcriptional regulator
C7M16_RS12005	COG1064	alcohol dehydrogenase
C7M16_RS12010	COG0693	protein deglycase activity
C7M16_RS12015	COG1621	beta-fructofuranosidase activity
C7M16_RS12020	COG3716	PTS system mannose fructose sorbose family IID component
C7M16_RS12025	COG3715	PTS system
C7M16_RS12030	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M16_RS12035	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M16_RS12040	COG3933	PFAM sigma-54 factor interaction domain-containing protein
C7M16_RS12040	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C7M16_RS12050	COG1113	amino acid transport
C7M16_RS12055	COG1280	lysine exporter protein (LysE YggA)
C7M16_RS12060	COG1378	Sugar-specific transcriptional regulator TrmB
C7M16_RS12065	COG1595	DNA-templated transcription, initiation
C7M16_RS12075	COG2755	lipolytic protein G-D-S-L family
C7M16_RS12075	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C7M16_RS12085	COG2124	cytochrome p450
C7M16_RS12085	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C7M16_RS12090	COG1309	transcriptional regulator
C7M16_RS12095	COG2226	methyltransferase
C7M16_RS12110	COG2116	formate transmembrane transporter activity
C7M16_RS12115	COG5609	conserved protein (DUF2294)
C7M16_RS12120	COG3383	formate dehydrogenase (NAD+) activity
C7M16_RS12125	COG2427	Protein of unknown function (DUF1641)
C7M16_RS12135	COG0626	cystathionine gamma-synthase activity
C7M16_RS12140	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7M16_RS12145	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C7M16_RS12150	COG2226	methyltransferase
C7M16_RS12165	COG0768	penicillin binding
C7M16_RS12170	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C7M16_RS12175	COG0572	uridine kinase
C7M16_RS12195	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C7M16_RS12200	COG3906	Belongs to the UPF0473 family
C7M16_RS12205	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C7M16_RS12210	COG4472	Bacterial protein of unknown function (DUF965)
C7M16_RS12215	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C7M16_RS12220	COG0628	permease
C7M16_RS12225	COG1126	abc transporter atp-binding protein
C7M16_RS12230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M16_RS12235	COG0765	amino acid transport
C7M16_RS12240	COG0765	amino acid transport
C7M16_RS12255	COG3881	PFAM PRC-barrel domain
C7M16_RS12260	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C7M16_RS12265	COG0457	Tetratricopeptide repeat
C7M16_RS12270	COG0482	sulfurtransferase activity
C7M16_RS12275	COG1104	cysteine desulfurase activity
C7M16_RS12280	COG1959	2 iron, 2 sulfur cluster binding
C7M16_RS12285	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C7M16_RS12290	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C7M16_RS12300	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C7M16_RS12305	COG0124	histidyl-tRNA synthetase
C7M16_RS12315	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M16_RS12315	COG4991	sh3 domain protein
C7M16_RS12315	COG3103	Sh3 type 3 domain protein
C7M16_RS12320	COG1490	D-aminoacyl-tRNA deacylase activity
C7M16_RS12325	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C7M16_RS12330	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7M16_RS12335	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
C7M16_RS12335	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C7M16_RS12340	COG5416	Lipopolysaccharide assembly protein A domain
C7M16_RS12345	COG0490	domain, Protein
C7M16_RS12350	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C7M16_RS12350	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C7M16_RS12360	COG2244	polysaccharide biosynthetic process
C7M16_RS12365	COG2323	membrane
C7M16_RS12375	COG1862	Preprotein translocase
C7M16_RS12380	COG0343	queuine tRNA-ribosyltransferase activity
C7M16_RS12385	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
C7M16_RS12395	COG2255	four-way junction helicase activity
C7M16_RS12400	COG0632	four-way junction helicase activity
C7M16_RS12410	COG2814	Major facilitator Superfamily
C7M16_RS12415	COG0673	inositol 2-dehydrogenase activity
C7M16_RS12420	COG2112	serine threonine protein kinase
C7M16_RS12440	COG1115	amino acid carrier protein
C7M16_RS12445	COG0217	transcriptional regulatory protein
C7M16_RS12455	COG1388	LysM domain
C7M16_RS12460	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
C7M16_RS12465	COG0157	Belongs to the NadC ModD family
C7M16_RS12470	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C7M16_RS12475	COG1104	cysteine desulfurase activity
C7M16_RS12480	COG1827	regulation of RNA biosynthetic process
C7M16_RS12485	COG0077	Prephenate dehydratase
C7M16_RS12490	COG4492	Belongs to the UPF0735 family
C7M16_RS12495	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C7M16_RS12500	COG3290	protein histidine kinase activity
C7M16_RS12510	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C7M16_RS12515	COG2868	ribosomal protein
C7M16_RS12520	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C7M16_RS12525	COG1994	Peptidase M50
C7M16_RS12530	COG0739	heme binding
C7M16_RS12535	COG2894	cell division
C7M16_RS12540	COG0850	regulation of cytokinetic process
C7M16_RS12545	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C7M16_RS12550	COG1792	Involved in formation and maintenance of cell shape
C7M16_RS12555	COG1077	Cell shape determining protein MreB Mrl
C7M16_RS12560	COG2003	Belongs to the UPF0758 family
C7M16_RS12565	COG0424	maF-like protein
C7M16_RS12575	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C7M16_RS12580	COG0285	dihydrofolate synthase activity
C7M16_RS12585	COG0525	valine-tRNA ligase activity
C7M16_RS12595	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7M16_RS12600	COG1388	LysM domain
C7M16_RS12605	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C7M16_RS12610	COG0113	porphobilinogen synthase activity
C7M16_RS12615	COG1587	Uroporphyrinogen-III synthase
C7M16_RS12620	COG0181	hydroxymethylbilane synthase activity
C7M16_RS12625	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C7M16_RS12630	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
C7M16_RS12640	COG0218	Necessary for normal cell division and for the maintenance of normal septation
C7M16_RS12645	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C7M16_RS12650	COG1067	ATP-dependent peptidase activity
C7M16_RS12650	COG0470	DNA polymerase III
C7M16_RS12655	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
C7M16_RS12660	COG0544	peptidyl-prolyl cis-trans isomerase activity
C7M16_RS12665	COG1477	protein flavinylation
C7M16_RS12665	COG0457	Tetratricopeptide repeat
C7M16_RS12670	COG0066	3-isopropylmalate dehydratase activity
C7M16_RS12675	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
C7M16_RS12680	COG0473	3-isopropylmalate dehydrogenase activity
C7M16_RS12685	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C7M16_RS12690	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
C7M16_RS12695	COG0440	acetolactate synthase activity
C7M16_RS12700	COG0028	Belongs to the TPP enzyme family
C7M16_RS12710	COG0454	-acetyltransferase
C7M16_RS12715	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
C7M16_RS12725	COG0622	Phosphoesterase
C7M16_RS12730	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C7M16_RS12735	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
C7M16_RS12740	COG5401	PFAM Sporulation and spore germination
C7M16_RS12745	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C7M16_RS12750	COG1846	Transcriptional regulator
C7M16_RS12755	COG2197	response regulator
C7M16_RS12760	COG0824	Thioesterase
C7M16_RS12765	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C7M16_RS12770	COG1053	succinate dehydrogenase
C7M16_RS12775	COG2009	succinate dehydrogenase
C7M16_RS12780	COG1719	4-vinyl reductase, 4VR
C7M16_RS12785	COG0527	aspartate kinase activity
C7M16_RS12790	COG0322	excinuclease ABC activity
C7M16_RS12795	COG3118	belongs to the thioredoxin family
C7M16_RS12800	COG3534	alpha-L-arabinofuranosidase
C7M16_RS12805	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C7M16_RS12810	COG2086	electron transfer activity
C7M16_RS12815	COG1024	Enoyl-CoA hydratase
C7M16_RS12820	COG1309	transcriptional regulator
C7M16_RS12825	COG0318	PFAM AMP-dependent synthetase and ligase
C7M16_RS12830	COG3766	membrane
C7M16_RS12835	COG1193	negative regulation of DNA recombination
C7M16_RS12840	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C7M16_RS12840	COG1796	DNA polymerase
C7M16_RS12845	COG1286	toxin biosynthetic process
C7M16_RS12850	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
C7M16_RS12855	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C7M16_RS12860	COG0072	phenylalanine-tRNA ligase activity
C7M16_RS12860	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M16_RS12865	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C7M16_RS12875	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7M16_RS12885	COG3835	regulator
C7M16_RS12890	COG0277	FAD linked oxidase domain protein
C7M16_RS12895	COG0247	lactate metabolic process
C7M16_RS12900	COG0346	lactoylglutathione lyase activity
C7M16_RS12910	COG1966	Carbon starvation protein
C7M16_RS12915	COG3534	alpha-L-arabinofuranosidase
C7M16_RS12920	COG0395	ABC-type sugar transport system, permease component
C7M16_RS12925	COG1175	transmembrane transport
C7M16_RS12930	COG1653	transport
C7M16_RS12935	COG0371	Dehydrogenase
C7M16_RS12940	COG0647	UMP catabolic process
C7M16_RS12945	COG0235	Class ii aldolase
C7M16_RS12950	COG1069	ribulokinase activity
C7M16_RS12955	COG2160	L-arabinose isomerase activity
C7M16_RS12960	COG3507	Belongs to the glycosyl hydrolase 43 family
C7M16_RS12965	COG1363	Peptidase, m42
C7M16_RS12975	COG3326	Membrane
C7M16_RS12980	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C7M16_RS12985	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C7M16_RS12990	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C7M16_RS13000	COG1346	cytolysis
C7M16_RS13005	COG1380	Effector of murein hydrolase LrgA
C7M16_RS13010	COG3279	Response regulator of the LytR AlgR family
C7M16_RS13015	COG3275	phosphorelay sensor kinase activity
C7M16_RS13025	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C7M16_RS13035	COG0398	Pfam SNARE associated Golgi protein
C7M16_RS13040	COG1484	DNA-dependent DNA replication
C7M16_RS13045	COG3611	Membrane attachment protein
C7M16_RS13050	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C7M16_RS13055	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
C7M16_RS13060	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C7M16_RS13065	COG1733	regulation of RNA biosynthetic process
C7M16_RS13070	COG2814	Major facilitator Superfamily
C7M16_RS13075	COG0656	L-ascorbic acid biosynthetic process
C7M16_RS13080	COG0237	dephospho-CoA kinase activity
C7M16_RS13085	COG1971	Probably functions as a manganese efflux pump
C7M16_RS13090	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C7M16_RS13095	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7M16_RS13095	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7M16_RS13100	COG5002	protein histidine kinase activity
C7M16_RS13105	COG0745	RESPONSE REGULATOR receiver
C7M16_RS13110	COG0039	L-malate dehydrogenase activity
C7M16_RS13115	COG0538	isocitrate dehydrogenase activity
C7M16_RS13120	COG0372	Belongs to the citrate synthase family
C7M16_RS13125	COG2707	UPF0756 membrane protein
C7M16_RS13130	COG0628	permease
C7M16_RS13135	COG3030	protein affecting phage T7 exclusion by the F plasmid
C7M16_RS13140	COG0469	pyruvate kinase activity
C7M16_RS13145	COG0205	6-phosphofructokinase activity
C7M16_RS13150	COG0825	malonyl-CoA metabolic process
C7M16_RS13155	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
C7M16_RS13160	COG0281	malic enzyme
C7M16_RS13165	COG0587	DNA-directed DNA polymerase activity
C7M16_RS13185	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C7M16_RS13195	COG4109	DRTGG domain
C7M16_RS13200	COG0730	response to heat
C7M16_RS13205	COG1473	amidohydrolase
C7M16_RS13210	COG0196	riboflavin kinase activity
C7M16_RS13215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M16_RS13220	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C7M16_RS13225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M16_RS13230	COG1126	abc transporter atp-binding protein
C7M16_RS13235	COG0765	amino acid transport
C7M16_RS13240	COG0765	amino acid transport
C7M16_RS13245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M16_RS13250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M16_RS13255	COG0454	-acetyltransferase
C7M16_RS13260	COG0583	DNA-binding transcription factor activity
C7M16_RS13265	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
C7M16_RS13270	COG1028	Short-chain dehydrogenase reductase Sdr
C7M16_RS13280	COG0165	Argininosuccinate lyase
C7M16_RS13285	COG0137	argininosuccinate synthase activity
C7M16_RS13290	COG0521	Mo-molybdopterin cofactor biosynthetic process
C7M16_RS13295	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C7M16_RS13305	COG0827	DNA restriction-modification system
C7M16_RS13310	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
C7M16_RS13315	COG3874	Sporulation protein YtfJ
C7M16_RS13325	COG1714	RDD family
C7M16_RS13330	COG0616	signal peptide processing
C7M16_RS13335	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C7M16_RS13340	COG1574	metal-dependent hydrolase with the TIM-barrel fold
C7M16_RS13345	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C7M16_RS13355	COG0301	tRNA thio-modification
C7M16_RS13360	COG1104	cysteine desulfurase activity
C7M16_RS13365	COG1114	Component of the transport system for branched-chain amino acids
C7M16_RS13370	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
C7M16_RS13375	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C7M16_RS13380	COG1309	transcriptional regulator
C7M16_RS13385	COG1956	GAF domain-containing protein
C7M16_RS13390	COG2199	diguanylate cyclase activity
C7M16_RS13390	COG2203	Gaf domain
C7M16_RS13400	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
C7M16_RS13405	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C7M16_RS13410	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C7M16_RS13415	COG0454	-acetyltransferase
C7M16_RS13420	COG0517	IMP dehydrogenase activity
C7M16_RS13425	COG0123	including yeast histone deacetylase and acetoin utilization protein
C7M16_RS13430	COG1360	Flagellar Motor Protein
C7M16_RS13435	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C7M16_RS13440	COG1609	Transcriptional regulator
C7M16_RS13445	COG1605	Chorismate mutase
C7M16_RS13445	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
C7M16_RS13450	COG3118	belongs to the thioredoxin family
C7M16_RS13455	COG4980	gas vesicle protein
C7M16_RS13460	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
C7M16_RS13465	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C7M16_RS13470	COG1674	ftsk spoiiie
C7M16_RS13475	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M16_RS13480	COG4848	Belongs to the UPF0354 family
C7M16_RS13485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M16_RS13500	COG1363	Peptidase, m42
C7M16_RS13505	COG5584	Small secreted protein
C7M16_RS13510	COG0281	malic enzyme
C7M16_RS13515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M16_RS13520	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C7M16_RS13530	COG0510	thiamine kinase activity
C7M16_RS13535	COG1523	belongs to the glycosyl hydrolase 13 family
C7M16_RS13540	COG1597	lipid kinase activity
C7M16_RS13550	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C7M16_RS13555	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7M16_RS13560	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M16_RS13565	COG2252	PERMEase
C7M16_RS13570	COG4473	ABC transporter
C7M16_RS13575	COG1131	(ABC) transporter
C7M16_RS13580	COG1349	DNA-binding transcription factor activity
C7M16_RS13585	COG1187	pseudouridine synthase activity
C7M16_RS13590	COG2244	polysaccharide biosynthetic process
C7M16_RS13595	COG2081	HI0933 family
C7M16_RS13600	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C7M16_RS13610	COG5578	integral membrane protein
C7M16_RS13615	COG0673	inositol 2-dehydrogenase activity
C7M16_RS13620	COG1653	transport
C7M16_RS13625	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
C7M16_RS13630	COG4209	transmembrane transport
C7M16_RS13635	COG2207	Transcriptional regulator
C7M16_RS13640	COG1653	transport
C7M16_RS13645	COG0395	ABC-type sugar transport system, permease component
C7M16_RS13650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M16_RS13655	COG2124	cytochrome p450
C7M16_RS13660	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C7M16_RS13670	COG0156	8-amino-7-oxononanoate synthase activity
C7M16_RS13675	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C7M16_RS13685	COG1073	alpha beta
C7M16_RS13710	COG1486	melibiose metabolic process
C7M16_RS13715	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7M16_RS13720	COG0495	leucyl-tRNA aminoacylation
C7M16_RS13730	COG2202	Pas domain
C7M16_RS13730	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M16_RS13735	COG2814	Major facilitator Superfamily
C7M16_RS13740	COG2433	Pfam Transposase IS66
C7M16_RS13745	COG0577	efflux transmembrane transporter activity
C7M16_RS13750	COG1136	(ABC) transporter
C7M16_RS13755	COG2205	protein histidine kinase activity
C7M16_RS13760	COG0745	RESPONSE REGULATOR receiver
C7M16_RS13765	COG0577	efflux transmembrane transporter activity
C7M16_RS13770	COG1136	(ABC) transporter
C7M16_RS13785	COG1131	(ABC) transporter
C7M16_RS13790	COG1725	Transcriptional regulator
C7M16_RS13805	COG1242	4 iron, 4 sulfur cluster binding
C7M16_RS13810	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
C7M16_RS13820	COG2267	carboxylic ester hydrolase activity
C7M16_RS13825	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C7M16_RS13830	COG1113	amino acid transport
C7M16_RS13835	COG0367	asparagine synthase
C7M16_RS13840	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C7M16_RS13845	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
C7M16_RS13855	COG1506	peptidase
C7M16_RS13860	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C7M16_RS13865	COG1116	anion transmembrane transporter activity
C7M16_RS13870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C7M16_RS13875	COG0494	nUDIX hydrolase
C7M16_RS13880	COG4824	toxin secretion phage lysis holin
C7M16_RS13885	COG0783	Belongs to the Dps family
C7M16_RS13900	COG1854	S-ribosylhomocysteine lyase activity
C7M16_RS13905	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C7M16_RS13910	COG0288	reversible hydration of carbon dioxide
C7M16_RS13915	COG0254	rRNA binding
C7M16_RS13920	COG1271	oxidase subunit
C7M16_RS13925	COG1294	oxidase, subunit
C7M16_RS13935	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7M16_RS13940	COG1321	iron dependent repressor
C7M16_RS13940	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7M16_RS13945	COG1121	(ABC) transporter
C7M16_RS13950	COG0803	Belongs to the bacterial solute-binding protein 9 family
C7M16_RS13955	COG4948	Mandelate Racemase Muconate Lactonizing
C7M16_RS13960	COG0318	PFAM AMP-dependent synthetase and ligase
C7M16_RS13965	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C7M16_RS13970	COG0596	Alpha beta hydrolase
C7M16_RS13975	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
C7M16_RS13980	COG1169	isochorismate synthase
C7M16_RS13985	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C7M16_RS13990	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7M16_RS13995	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C7M16_RS14000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M16_RS14005	COG0438	transferase activity, transferring glycosyl groups
C7M16_RS14015	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7M16_RS14020	COG0438	transferase activity, transferring glycosyl groups
C7M16_RS14025	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7M16_RS14030	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
C7M16_RS14035	COG0058	SHG alpha-glucan phosphorylase activity
C7M16_RS14040	COG0297	glycogen (starch) synthase activity
C7M16_RS14045	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C7M16_RS14050	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C7M16_RS14055	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C7M16_RS14180	COG3859	Proton-coupled thiamine transporter YuaJ
C7M16_RS14185	COG1247	-acetyltransferase
C7M16_RS14190	COG2268	Band 7 protein
C7M16_RS14195	COG1585	Membrane protein implicated in regulation of membrane protease activity
C7M16_RS14200	COG2318	DinB family
C7M16_RS14210	COG1454	alcohol dehydrogenase
C7M16_RS14220	COG1510	regulation of RNA biosynthetic process
C7M16_RS14230	COG0569	domain protein
C7M16_RS14235	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7M16_RS14240	COG4682	membrane
C7M16_RS14245	COG1705	Flagellar rod assembly protein muramidase FlgJ
C7M16_RS14250	COG0477	Major facilitator Superfamily
C7M16_RS14255	COG5553	Cysteine dioxygenase type I
C7M16_RS14265	COG1968	undecaprenyl-diphosphatase activity
C7M16_RS14270	COG0628	permease
C7M16_RS14275	COG0673	inositol 2-dehydrogenase activity
C7M16_RS14280	COG4806	L-rhamnose isomerase
C7M16_RS14285	COG3254	rhamnose metabolic process
C7M16_RS14290	COG1070	Carbohydrate kinase
C7M16_RS14295	COG1349	DNA-binding transcription factor activity
C7M16_RS14300	COG1028	Short-chain dehydrogenase reductase Sdr
C7M16_RS14300	COG3347	Dehydrogenase
C7M16_RS14305	COG0840	transmembrane signaling receptor activity
C7M16_RS14310	COG0840	transmembrane signaling receptor activity
C7M16_RS14315	COG0840	transmembrane signaling receptor activity
C7M16_RS14320	COG0840	transmembrane signaling receptor activity
C7M16_RS14335	COG0432	Pfam Uncharacterised protein family UPF0047
C7M16_RS14345	COG0366	Alpha amylase catalytic
C7M16_RS14350	COG1253	flavin adenine dinucleotide binding
C7M16_RS14355	COG2738	Putative neutral zinc metallopeptidase
C7M16_RS14370	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C7M16_RS14385	COG0166	Belongs to the GPI family
C7M16_RS14390	COG1979	alcohol dehydrogenase
C7M16_RS14395	COG1979	alcohol dehydrogenase
C7M16_RS14400	COG2155	Conserved Protein
C7M16_RS14405	COG1098	S1 RNA binding domain
C7M16_RS14410	COG0436	Aminotransferase
C7M16_RS14415	COG1522	sequence-specific DNA binding
C7M16_RS14420	COG2267	carboxylic ester hydrolase activity
C7M16_RS14430	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C7M16_RS14435	COG2205	protein histidine kinase activity
C7M16_RS14445	COG5018	Exonuclease
C7M16_RS14455	COG2814	Major facilitator Superfamily
C7M16_RS14460	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7M16_RS14465	COG3011	Protein conserved in bacteria
C7M16_RS14475	COG3290	protein histidine kinase activity
C7M16_RS14480	COG4565	transcriptional regulatory protein
C7M16_RS14505	COG3493	citrate carrier protein
C7M16_RS14515	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C7M16_RS14515	COG2111	Na H antiporter
C7M16_RS14520	COG2111	Na H antiporter
C7M16_RS14525	COG1006	Multisubunit Na H antiporter MnhC subunit
C7M16_RS14530	COG0651	ATP synthesis coupled electron transport
C7M16_RS14535	COG1863	multisubunit Na H antiporter MnhE subunit
C7M16_RS14540	COG2212	antiporter activity
C7M16_RS14545	COG1320	monovalent cation:proton antiporter activity
C7M16_RS14550	COG2050	protein possibly involved in aromatic compounds catabolism
C7M16_RS14555	COG2197	response regulator
C7M16_RS14560	COG4585	Histidine kinase
C7M16_RS14570	COG0142	geranyltranstransferase activity
C7M16_RS14590	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
C7M16_RS14595	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C7M16_RS14600	COG1335	isochorismatase
C7M16_RS14605	COG5506	Protein of unknown function (DUF1694)
C7M16_RS14620	COG0628	permease
C7M16_RS14635	COG1418	mRNA catabolic process
C7M16_RS14640	COG1028	Short-chain dehydrogenase reductase Sdr
C7M16_RS14650	COG1511	domain protein
C7M16_RS14655	COG1674	ftsk spoiiie
C7M16_RS14655	COG0433	COG0433 Predicted ATPase
C7M16_RS14660	COG4499	WXG100 protein secretion system (Wss), protein YukC
C7M16_RS14665	COG5417	Belongs to the EsaB family
C7M16_RS14670	COG4842	Belongs to the WXG100 family
C7M16_RS14675	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
C7M16_RS14675	COG2508	Transcriptional regulator
C7M16_RS14680	COG0686	Belongs to the AlaDH PNT family
C7M16_RS14685	COG5634	Uncharacterized conserved protein (DUF2278)
C7M16_RS14690	COG3251	PFAM MbtH domain protein
C7M16_RS14695	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M16_RS14700	COG1535	isochorismatase
C7M16_RS14700	COG3433	isochorismatase activity
C7M16_RS14705	COG1021	2,3-dihydroxybenzoate-AMP ligase
C7M16_RS14710	COG1169	isochorismate synthase
C7M16_RS14715	COG1028	Short-chain dehydrogenase reductase Sdr
C7M16_RS14720	COG2819	hydrolase of the alpha beta superfamily
C7M16_RS14725	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C7M16_RS14730	COG1268	BioY protein
C7M16_RS14735	COG2056	Na+-H+ antiporter family
C7M16_RS14740	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C7M16_RS14745	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
C7M16_RS14750	COG3584	3D domain protein
C7M16_RS14765	COG1252	NADH dehydrogenase
C7M16_RS14770	COG0492	ferredoxin-NADP+ reductase activity
C7M16_RS14780	COG0516	GMP reductase activity
C7M16_RS14785	COG2808	Putative FMN-binding domain
C7M16_RS14790	COG0456	acetyltransferase
C7M16_RS14795	COG0316	Belongs to the HesB IscA family
C7M16_RS14800	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
C7M16_RS14805	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7M16_RS14810	COG4844	belongs to the
C7M16_RS14815	COG1252	NADH dehydrogenase
C7M16_RS14820	COG4837	Protein of unknown function (DUF1462)
C7M16_RS14825	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
C7M16_RS14830	COG1506	peptidase
C7M16_RS14830	COG4946	Tricorn protease homolog
C7M16_RS14830	COG0823	Involved in the tonB-independent uptake of proteins
C7M16_RS14835	COG0083	homoserine kinase activity
C7M16_RS14840	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C7M16_RS14845	COG0460	homoserine dehydrogenase
C7M16_RS14850	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7M16_RS14855	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C7M16_RS14860	COG0647	UMP catabolic process
C7M16_RS14865	COG2445	Protein of unknown function DUF86
C7M16_RS14870	COG4470	Protein conserved in bacteria
C7M16_RS14880	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C7M16_RS14885	COG0739	heme binding
C7M16_RS14895	COG3377	Domain of unknown function (DUF1805)
C7M16_RS14900	COG0737	Belongs to the 5'-nucleotidase family
C7M16_RS14905	COG0730	response to heat
C7M16_RS14910	COG1801	Protein of unknown function DUF72
C7M16_RS14920	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C7M16_RS14925	COG2508	Transcriptional regulator
C7M16_RS14930	COG2233	PERMEase
C7M16_RS14935	COG2233	PERMEase
C7M16_RS14940	COG3195	allantoin biosynthetic process
C7M16_RS14940	COG3648	Uricase
C7M16_RS14945	COG2351	hydroxyisourate hydrolase activity
C7M16_RS14955	COG2080	2 iron, 2 sulfur cluster binding
C7M16_RS14960	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C7M16_RS14965	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C7M16_RS14970	COG2068	MobA-Related Protein
C7M16_RS14975	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C7M16_RS14980	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C7M16_RS14985	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M16_RS14995	COG2356	endonuclease I
C7M16_RS15000	COG3842	ATPase activity
C7M16_RS15005	COG2188	Transcriptional regulator
C7M16_RS15010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7M16_RS15015	COG0395	ABC-type sugar transport system, permease component
C7M16_RS15020	COG1175	transmembrane transport
C7M16_RS15025	COG1653	transport
C7M16_RS15030	COG2222	sugar isomerase
C7M16_RS15035	COG0322	excinuclease ABC activity
C7M16_RS15040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7M16_RS15055	COG0346	lactoylglutathione lyase activity
C7M16_RS15060	COG0640	Transcriptional regulator
C7M16_RS15065	COG0719	Fe-S assembly protein
C7M16_RS15070	COG0822	iron-sulfur transferase activity
C7M16_RS15075	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C7M16_RS15080	COG0719	Fe-S assembly protein
C7M16_RS15085	COG0396	ATPase activity
C7M16_RS15095	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C7M16_RS15100	COG1464	Belongs to the NlpA lipoprotein family
C7M16_RS15105	COG2011	ABC-type metal ion transport system permease component
C7M16_RS15110	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C7M16_RS15120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M16_RS15125	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C7M16_RS15135	COG0509	glycine decarboxylation via glycine cleavage system
C7M16_RS15140	COG1393	Belongs to the ArsC family
C7M16_RS15145	COG1960	acyl-CoA dehydrogenase activity
C7M16_RS15150	COG0183	Belongs to the thiolase family
C7M16_RS15155	COG1250	3-hydroxyacyl-CoA dehydrogenase
C7M16_RS15155	COG1024	Enoyl-CoA hydratase
C7M16_RS15165	COG0506	proline dehydrogenase activity
C7M16_RS15175	COG5577	PFAM Coat F domain
C7M16_RS15180	COG1846	Transcriptional regulator
C7M16_RS15185	COG0477	Major facilitator Superfamily
C7M16_RS15190	COG1942	4-Oxalocrotonate Tautomerase
C7M16_RS15195	COG1028	Short-chain dehydrogenase reductase Sdr
C7M16_RS15200	COG0583	DNA-binding transcription factor activity
C7M16_RS15210	COG1120	ATPase activity
C7M16_RS15225	COG1028	Short-chain dehydrogenase reductase Sdr
C7M16_RS15230	COG0783	Belongs to the Dps family
C7M16_RS15235	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M16_RS15240	COG0745	RESPONSE REGULATOR receiver
C7M16_RS15245	COG2770	Histidine kinase
C7M16_RS15245	COG2205	protein histidine kinase activity
C7M16_RS15255	COG1309	transcriptional regulator
C7M16_RS15260	COG0114	fumarate hydratase activity
C7M16_RS15270	COG0697	spore germination
C7M16_RS15275	COG0814	amino acid
C7M16_RS15285	COG2197	response regulator
C7M16_RS15290	COG4585	Histidine kinase
C7M16_RS15295	COG4758	membrane
C7M16_RS15300	COG3595	metallopeptidase activity
C7M16_RS15305	COG1842	Phage shock protein A
C7M16_RS15310	COG4758	membrane
C7M16_RS15315	COG2814	Major facilitator Superfamily
C7M16_RS15320	COG2096	Adenosyltransferase
C7M16_RS15325	COG1120	ATPase activity
C7M16_RS15330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M16_RS15335	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M16_RS15340	COG1028	Short-chain dehydrogenase reductase Sdr
C7M16_RS15345	COG3386	PFAM SMP-30 Gluconolaconase
C7M16_RS15350	COG2205	protein histidine kinase activity
C7M16_RS15355	COG0745	RESPONSE REGULATOR receiver
C7M16_RS15365	COG1191	sigma factor activity
C7M16_RS15375	COG2140	Oxalate decarboxylase
C7M16_RS15385	COG0577	efflux transmembrane transporter activity
C7M16_RS15390	COG1136	(ABC) transporter
C7M16_RS15395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7M16_RS15400	COG1120	ATPase activity
C7M16_RS15405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M16_RS15410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M16_RS15415	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M16_RS15420	COG0531	amino acid
C7M16_RS15430	COG1988	membrane-bound metal-dependent
C7M16_RS15435	COG1368	sulfuric ester hydrolase activity
C7M16_RS15440	COG1910	domain protein
C7M16_RS15445	COG0725	ABC transporter, periplasmic molybdate-binding protein
C7M16_RS15450	COG4149	molybdate abc transporter
C7M16_RS15455	COG0656	L-ascorbic acid biosynthetic process
C7M16_RS15465	COG0025	NhaP-type Na H and K H
C7M16_RS15470	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7M16_RS15475	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C7M16_RS15480	COG3973	AAA domain
C7M16_RS15490	COG2860	membrane
C7M16_RS15495	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C7M16_RS15500	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C7M16_RS15505	COG2217	Heavy metal translocating P-type atpase
C7M16_RS15510	COG2217	Heavy metal translocating P-type atpase
C7M16_RS15515	COG2608	mercury ion transmembrane transporter activity
C7M16_RS15520	COG1937	Protein conserved in bacteria
C7M16_RS15525	COG0673	inositol 2-dehydrogenase activity
C7M16_RS15530	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C7M16_RS15535	COG1289	transmembrane transporter activity
C7M16_RS15545	COG2076	Multidrug Resistance protein
C7M16_RS15550	COG1309	transcriptional regulator
C7M16_RS15555	COG1028	Short-chain dehydrogenase reductase Sdr
C7M16_RS15565	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
C7M16_RS15570	COG0557	exoribonuclease II activity
C7M16_RS15575	COG1647	Serine aminopeptidase, S33
C7M16_RS15580	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C7M16_RS15585	COG0596	Alpha beta hydrolase
C7M16_RS15590	COG1476	TRANSCRIPTIONal
C7M16_RS15595	COG1396	sequence-specific DNA binding
C7M16_RS15600	COG1396	sequence-specific DNA binding
C7M16_RS15605	COG1733	regulation of RNA biosynthetic process
C7M16_RS15615	COG1174	glycine betaine transport
C7M16_RS15620	COG1732	Glycine betaine
C7M16_RS15625	COG1174	glycine betaine transport
C7M16_RS15630	COG0517	IMP dehydrogenase activity
C7M16_RS15630	COG1125	glycine betaine transport
C7M16_RS15635	COG1510	regulation of RNA biosynthetic process
C7M16_RS15655	COG5658	integral membrane protein
C7M16_RS15660	COG0640	Transcriptional regulator
C7M16_RS15665	COG1174	glycine betaine transport
C7M16_RS15670	COG1732	Glycine betaine
C7M16_RS15675	COG1174	glycine betaine transport
C7M16_RS15680	COG1125	glycine betaine transport
C7M16_RS15680	COG0517	IMP dehydrogenase activity
C7M16_RS15685	COG1510	regulation of RNA biosynthetic process
C7M16_RS15700	COG3064	Membrane
C7M16_RS15705	COG4640	response to antibiotic
C7M16_RS15710	COG0456	acetyltransferase
C7M16_RS15715	COG0148	phosphopyruvate hydratase activity
C7M16_RS15720	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
C7M16_RS15725	COG0149	triose-phosphate isomerase activity
C7M16_RS15730	COG0126	phosphoglycerate kinase activity
C7M16_RS15735	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C7M16_RS15740	COG2390	Transcriptional regulator
C7M16_RS15745	COG2814	Major facilitator Superfamily
C7M16_RS15750	COG1609	Transcriptional regulator
C7M16_RS15755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M16_RS15760	COG0583	DNA-binding transcription factor activity
C7M16_RS15765	COG0697	spore germination
C7M16_RS15770	COG1113	amino acid transport
C7M16_RS15775	COG3858	chitin binding
C7M16_RS15780	COG1556	Lactate utilization protein
C7M16_RS15785	COG1139	Iron-sulfur cluster binding protein
C7M16_RS15790	COG0247	lactate metabolic process
C7M16_RS15795	COG2197	response regulator
C7M16_RS15800	COG4585	Histidine kinase
C7M16_RS15805	COG0842	Transport permease protein
C7M16_RS15810	COG1131	(ABC) transporter
C7M16_RS15815	COG0596	Alpha beta hydrolase
C7M16_RS15820	COG2208	phosphoserine phosphatase activity
C7M16_RS15825	COG3867	Arabinogalactan endo-beta-1,4-galactanase
C7M16_RS15830	COG1874	Beta-galactosidase
C7M16_RS15835	COG3833	ABC-type maltose transport systems, permease component
C7M16_RS15840	COG1175	transmembrane transport
C7M16_RS15845	COG2182	Extracellular solute-binding protein
C7M16_RS15850	COG1609	Transcriptional regulator
C7M16_RS15855	COG2186	Transcriptional regulator
C7M16_RS15860	COG1620	l-lactate permease
C7M16_RS15865	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C7M16_RS15875	COG5039	Polysaccharide pyruvyl transferase
C7M16_RS15880	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C7M16_RS15885	COG0110	maltose O-acetyltransferase activity
C7M16_RS15890	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C7M16_RS15895	COG2244	polysaccharide biosynthetic process
C7M16_RS15900	COG1216	Glycosyl transferase, family 2
C7M16_RS15905	COG5039	Polysaccharide pyruvyl transferase
C7M16_RS15910	COG1216	Glycosyl transferase, family 2
C7M16_RS15920	COG0438	transferase activity, transferring glycosyl groups
C7M16_RS15925	COG1215	transferase activity, transferring glycosyl groups
C7M16_RS15930	COG0438	transferase activity, transferring glycosyl groups
C7M16_RS15935	COG1086	Polysaccharide biosynthesis protein
C7M16_RS15940	COG0489	protein tyrosine kinase activity
C7M16_RS15945	COG3944	biosynthesis protein
C7M16_RS15950	COG1396	sequence-specific DNA binding
C7M16_RS15955	COG2272	Belongs to the type-B carboxylesterase lipase family
C7M16_RS15965	COG3479	Phenolic acid decarboxylase
C7M16_RS15975	COG1794	racemase activity, acting on amino acids and derivatives
C7M16_RS15980	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M16_RS15985	COG1621	beta-fructofuranosidase activity
C7M16_RS15990	COG1621	beta-fructofuranosidase activity
C7M16_RS15995	COG0531	amino acid
C7M16_RS16000	COG1309	transcriptional regulator
C7M16_RS16005	COG2076	Multidrug Resistance protein
C7M16_RS16010	COG2076	Multidrug Resistance protein
C7M16_RS16020	COG0277	FAD linked oxidase domain protein
C7M16_RS16025	COG3621	Patatin-like phospholipase
C7M16_RS16035	COG0740	serine-type endopeptidase activity
C7M16_RS16040	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7M16_RS16045	COG0366	Alpha amylase catalytic
C7M16_RS16050	COG1554	hydrolase, family 65, central catalytic
C7M16_RS16055	COG5521	maltodextrose utilization protein MalA
C7M16_RS16060	COG3833	ABC-type maltose transport systems, permease component
C7M16_RS16065	COG1175	transmembrane transport
C7M16_RS16070	COG2182	Extracellular solute-binding protein
C7M16_RS16075	COG0366	Alpha amylase catalytic
C7M16_RS16080	COG1609	Transcriptional regulator
C7M16_RS16085	COG1611	Belongs to the LOG family
C7M16_RS16090	COG1694	Mazg nucleotide pyrophosphohydrolase
C7M16_RS16095	COG0659	secondary active sulfate transmembrane transporter activity
C7M16_RS16100	COG0288	reversible hydration of carbon dioxide
C7M16_RS16105	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7M16_RS16110	COG0577	efflux transmembrane transporter activity
C7M16_RS16115	COG1136	(ABC) transporter
C7M16_RS16120	COG5002	protein histidine kinase activity
C7M16_RS16125	COG0745	RESPONSE REGULATOR receiver
C7M16_RS16135	COG2162	N-hydroxyarylamine O-acetyltransferase activity
C7M16_RS16140	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M16_RS16145	COG1481	regulation of sporulation
C7M16_RS16150	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C7M16_RS16155	COG1660	Displays ATPase and GTPase activities
C7M16_RS16160	COG1051	belongs to the nudix hydrolase family
C7M16_RS16165	COG0492	ferredoxin-NADP+ reductase activity
C7M16_RS16170	COG0791	NLP P60 protein
C7M16_RS16170	COG3883	PFAM NLP P60 protein
C7M16_RS16175	COG0457	Tetratricopeptide repeat
C7M16_RS16180	COG1132	(ABC) transporter
C7M16_RS16200	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C7M16_RS16200	COG0140	phosphoribosyl-ATP diphosphatase activity
C7M16_RS16205	COG0107	imidazoleglycerol-phosphate synthase activity
C7M16_RS16210	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
C7M16_RS16215	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C7M16_RS16220	COG0131	Imidazoleglycerol-phosphate dehydratase
C7M16_RS16225	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C7M16_RS16230	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C7M16_RS16235	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
C7M16_RS16240	COG4990	cell redox homeostasis
C7M16_RS16245	COG5297	Belongs to the glycosyl hydrolase family 6
C7M16_RS16250	COG0110	maltose O-acetyltransferase activity
C7M16_RS16255	COG0546	phosphoglycolate phosphatase activity
C7M16_RS16260	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
C7M16_RS16265	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C7M16_RS16270	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
C7M16_RS16275	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C7M16_RS16280	COG0363	glucosamine-6-phosphate deaminase activity
C7M16_RS16290	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C7M16_RS16295	COG1846	Transcriptional regulator
C7M16_RS16300	COG2124	cytochrome p450
C7M16_RS16310	COG1846	Transcriptional regulator
C7M16_RS16315	COG2814	Major facilitator Superfamily
C7M16_RS16320	COG1950	PFAM Membrane protein of
C7M16_RS16325	COG1983	PspC domain protein
C7M16_RS16330	COG3595	metallopeptidase activity
C7M16_RS16345	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C7M16_RS16350	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C7M16_RS16355	COG0556	nucleotide-excision repair
C7M16_RS16360	COG4897	Protein conserved in bacteria
C7M16_RS16365	COG0574	Belongs to the PEP-utilizing enzyme family
C7M16_RS16365	COG3848	Pyruvate phosphate dikinase
C7M16_RS16370	COG1309	transcriptional regulator
C7M16_RS16375	COG2814	Major facilitator Superfamily
C7M16_RS16380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M16_RS16390	COG0793	Belongs to the peptidase S41A family
C7M16_RS16390	COG3409	Peptidoglycan-binding domain 1 protein
C7M16_RS16395	COG2177	Part of the ABC transporter FtsEX involved in
C7M16_RS16400	COG2884	Cell division ATP-binding protein ftsE
C7M16_RS16405	COG2010	Cytochrome c
C7M16_RS16410	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M16_RS16420	COG0653	protein targeting
C7M16_RS16425	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C7M16_RS16440	COG1516	flagellar protein fliS
C7M16_RS16445	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C7M16_RS16450	COG1334	flagellar protein FlaG
C7M16_RS16455	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C7M16_RS16460	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
C7M16_RS16465	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
C7M16_RS16475	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C7M16_RS16480	COG4786	Flagellar basal body rod
C7M16_RS16480	COG1256	bacterial-type flagellum assembly
C7M16_RS16485	COG3418	PFAM FlgN family protein
C7M16_RS16490	COG2747	anti-sigma28 factor FlgM
C7M16_RS16500	COG1040	competence protein
C7M16_RS16510	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
C7M16_RS16515	COG1307	EDD domain protein, DegV family
C7M16_RS16520	COG2197	response regulator
C7M16_RS16525	COG4585	Histidine kinase
C7M16_RS16530	COG1739	Uncharacterized protein family UPF0029
C7M16_RS16535	COG1316	TRANSCRIPTIONal
C7M16_RS16540	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C7M16_RS16545	COG0438	transferase activity, transferring glycosyl groups
C7M16_RS16550	COG1215	transferase activity, transferring glycosyl groups
C7M16_RS16555	COG3206	protein involved in exopolysaccharide biosynthesis
C7M16_RS16560	COG3307	-O-antigen
C7M16_RS16565	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C7M16_RS16570	COG0297	glycogen (starch) synthase activity
C7M16_RS16570	COG0438	transferase activity, transferring glycosyl groups
C7M16_RS16575	COG2244	polysaccharide biosynthetic process
C7M16_RS16590	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M16_RS16590	COG2247	cell wall binding repeat
C7M16_RS16595	COG2385	sporulation resulting in formation of a cellular spore
C7M16_RS16595	COG2247	cell wall binding repeat
C7M16_RS16605	COG1316	TRANSCRIPTIONal
C7M16_RS16610	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C7M16_RS16630	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7M16_RS16635	COG1134	teichoic acid transport
C7M16_RS16640	COG1682	transport, permease protein
C7M16_RS16655	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7M16_RS16655	COG1215	transferase activity, transferring glycosyl groups
C7M16_RS16660	COG0463	Glycosyl transferase, family 2
C7M16_RS16705	COG4193	domain, Protein
C7M16_RS16710	COG1482	cell wall glycoprotein biosynthetic process
C7M16_RS16715	COG0697	spore germination
C7M16_RS16720	COG0814	amino acid
C7M16_RS16730	COG2814	Major facilitator Superfamily
C7M16_RS16735	COG1316	TRANSCRIPTIONal
C7M16_RS16740	COG0561	phosphatase activity
C7M16_RS16745	COG0791	NLP P60 protein
C7M16_RS16755	COG2843	Capsule synthesis protein
C7M16_RS16765	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C7M16_RS16770	COG1609	Transcriptional regulator
C7M16_RS16775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7M16_RS16780	COG1869	D-ribose catabolic process
C7M16_RS16785	COG1129	ABC transporter
C7M16_RS16790	COG1172	Belongs to the binding-protein-dependent transport system permease family
C7M16_RS16795	COG1879	ABC-type sugar transport system periplasmic component
C7M16_RS16800	COG3103	Sh3 type 3 domain protein
C7M16_RS16810	COG2249	NAD(P)H dehydrogenase (quinone) activity
C7M16_RS16815	COG3527	Alpha-acetolactate decarboxylase
C7M16_RS16820	COG0028	Belongs to the TPP enzyme family
C7M16_RS16825	COG0583	DNA-binding transcription factor activity
C7M16_RS16830	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C7M16_RS16845	COG5337	Spore coat protein CotH
C7M16_RS16855	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C7M16_RS16865	COG0405	Gamma-glutamyltransferase
C7M16_RS16870	COG1522	sequence-specific DNA binding
C7M16_RS16875	COG2059	Chromate
C7M16_RS16880	COG2059	Chromate
C7M16_RS16890	COG0655	NAD(P)H dehydrogenase (quinone) activity
C7M16_RS16895	COG0583	DNA-binding transcription factor activity
C7M16_RS16910	COG5444	nuclease activity
C7M16_RS16930	COG3878	Protein conserved in bacteria
C7M16_RS16935	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C7M16_RS16940	COG4464	protein tyrosine phosphatase activity
C7M16_RS16945	COG0489	protein tyrosine kinase activity
C7M16_RS16950	COG3944	biosynthesis protein
C7M16_RS16960	COG4715	Zinc finger, swim domain protein
C7M16_RS16965	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C7M16_RS16970	COG0561	phosphatase activity
C7M16_RS16975	COG1349	DNA-binding transcription factor activity
C7M16_RS16980	COG0629	single-stranded DNA binding
C7M16_RS16995	COG3764	Sortase (surface protein transpeptidase)
C7M16_RS17005	COG0745	RESPONSE REGULATOR receiver
C7M16_RS17005	COG2972	Histidine kinase
C7M16_RS17010	COG1970	mechanosensitive ion channel activity
C7M16_RS17015	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C7M16_RS17020	COG0457	Tetratricopeptide repeat
C7M16_RS17025	COG4786	Flagellar basal body rod
C7M16_RS17030	COG4786	Flagellar basal body rod
C7M16_RS17035	COG1077	Cell shape determining protein MreB Mrl
C7M16_RS17040	COG1609	Transcriptional regulator
C7M16_RS17050	COG1846	Transcriptional regulator
C7M16_RS17055	COG2814	Major facilitator Superfamily
C7M16_RS17060	COG3420	alginic acid biosynthetic process
C7M16_RS17065	COG1953	Uracil, thiamine, allantoin
C7M16_RS17070	COG0477	Major facilitator Superfamily
C7M16_RS17075	COG1335	isochorismatase
C7M16_RS17085	COG0004	ammonium transporteR
C7M16_RS17090	COG0347	Belongs to the P(II) protein family
C7M16_RS17095	COG0671	phosphoesterase, PA-phosphatase related
C7M16_RS17105	COG0739	heme binding
C7M16_RS17110	COG1247	-acetyltransferase
C7M16_RS17130	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7M16_RS17135	COG0789	Transcriptional regulator
C7M16_RS17145	COG2910	NAD(P)H-binding
C7M16_RS17150	COG1959	2 iron, 2 sulfur cluster binding
C7M16_RS17155	COG0804	urea catabolic process
C7M16_RS17160	COG0832	Belongs to the urease beta subunit family
C7M16_RS17165	COG0831	urea catabolic process
C7M16_RS17180	COG3237	CsbD-like
C7M16_RS17185	COG1994	Peptidase M50
C7M16_RS17190	COG0457	Tetratricopeptide repeat
C7M16_RS17195	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C7M16_RS17200	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C7M16_RS17210	COG2304	oxidoreductase activity
C7M16_RS17220	COG2304	oxidoreductase activity
C7M16_RS17225	COG2385	sporulation resulting in formation of a cellular spore
C7M16_RS17230	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C7M16_RS17240	COG4836	Membrane
C7M16_RS17250	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C7M16_RS17255	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C7M16_RS17260	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C7M16_RS17265	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
C7M16_RS17270	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C7M16_RS17275	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
C7M16_RS17280	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C7M16_RS17285	COG0356	it plays a direct role in the translocation of protons across the membrane
C7M16_RS17295	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C7M16_RS17300	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C7M16_RS17305	COG4475	Protein of unknown function (DUF436)
C7M16_RS17310	COG0698	ribose 5-phosphate isomerase
C7M16_RS17315	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7M16_RS17320	COG1971	Probably functions as a manganese efflux pump
C7M16_RS17325	COG0009	L-threonylcarbamoyladenylate synthase
C7M16_RS17330	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C7M16_RS17350	COG2890	protein-(glutamine-N5) methyltransferase activity
C7M16_RS17355	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C7M16_RS17360	COG0346	lactoylglutathione lyase activity
C7M16_RS17365	COG0789	Transcriptional regulator
C7M16_RS17370	COG0679	Auxin Efflux Carrier
C7M16_RS17375	COG0281	malic enzyme
C7M16_RS17380	COG1435	thymidine kinase activity
C7M16_RS17385	COG0254	rRNA binding
C7M16_RS17390	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C7M16_RS17400	COG1494	fructose-1,6-bisphosphatase
C7M16_RS17405	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C7M16_RS17410	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C7M16_RS17415	COG0191	fructose-bisphosphate aldolase activity
C7M16_RS17420	COG2204	response regulator
C7M16_RS17425	COG4821	SIS domain
C7M16_RS17430	COG0504	CTP synthase activity
C7M16_RS17435	COG3343	RNA polymerase activity
C7M16_RS17440	COG1960	acyl-CoA dehydrogenase activity
C7M16_RS17445	COG2181	nitrate reductase activity
C7M16_RS17445	COG0247	lactate metabolic process
C7M16_RS17450	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7M16_RS17455	COG4294	response to UV
C7M16_RS17465	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C7M16_RS17470	COG1132	(ABC) transporter
C7M16_RS17475	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7M16_RS17485	COG2181	nitrate reductase activity
C7M16_RS17490	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C7M16_RS17495	COG1140	nitrate reductase beta subunit
C7M16_RS17500	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C7M16_RS17505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7M16_RS17515	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7M16_RS17520	COG2223	nitrite transmembrane transporter activity
C7M16_RS17525	COG0018	arginyl-trna synthetase
C7M16_RS17530	COG4506	Protein conserved in bacteria
C7M16_RS17545	COG0535	radical SAM domain protein
C7M16_RS17555	COG1131	(ABC) transporter
C7M16_RS17560	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C7M16_RS17565	COG0612	Peptidase, M16
C7M16_RS17570	COG0612	Peptidase, M16
C7M16_RS17580	COG3391	amine dehydrogenase activity
C7M16_RS17585	COG3391	amine dehydrogenase activity
C7M16_RS17595	COG0457	Tetratricopeptide repeat
C7M16_RS17610	COG0010	Belongs to the arginase family
C7M16_RS17615	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
C7M16_RS17620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7M16_RS17630	COG1994	Peptidase M50
C7M16_RS17635	COG1942	4-Oxalocrotonate Tautomerase
C7M16_RS17640	COG1846	Transcriptional regulator
C7M16_RS17645	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C7M16_RS17650	COG0477	Major facilitator Superfamily
C7M16_RS17655	COG1959	2 iron, 2 sulfur cluster binding
C7M16_RS17660	COG3465	dGTPase activity
C7M16_RS17665	COG1078	dGTPase activity
C7M16_RS17670	COG4844	belongs to the
C7M16_RS17680	COG0697	spore germination
C7M16_RS17685	COG0095	Lipoate-protein ligase
C7M16_RS17690	COG0583	DNA-binding transcription factor activity
C7M16_RS17695	COG0280	phosphate acetyltransferase
C7M16_RS17705	COG1028	Short-chain dehydrogenase reductase Sdr
C7M16_RS17710	COG0436	Aminotransferase
C7M16_RS17715	COG2814	Major facilitator Superfamily
C7M16_RS17720	COG0151	Belongs to the GarS family
C7M16_RS17725	COG1028	Short-chain dehydrogenase reductase Sdr
C7M16_RS17730	COG1917	Cupin 2, conserved barrel domain protein
C7M16_RS17735	COG0077	Prephenate dehydratase
C7M16_RS17740	COG2814	Major facilitator Superfamily
C7M16_RS17745	COG0833	amino acid
C7M16_RS17750	COG4187	Peptidase family M20/M25/M40
C7M16_RS17755	COG1012	belongs to the aldehyde dehydrogenase family
C7M16_RS17760	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C7M16_RS17770	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
C7M16_RS17775	COG1091	dTDP-4-dehydrorhamnose reductase activity
C7M16_RS17780	COG1088	dTDP-glucose 4,6-dehydratase activity
C7M16_RS17785	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C7M16_RS17790	COG3980	spore coat polysaccharide biosynthesis protein
C7M16_RS17795	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
C7M16_RS17800	COG2089	acid synthase
C7M16_RS17805	COG0456	acetyltransferase
C7M16_RS17810	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C7M16_RS17815	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7M16_RS17820	COG0463	Glycosyl transferase, family 2
C7M16_RS17830	COG2363	Small membrane protein
C7M16_RS17835	COG2233	PERMEase
C7M16_RS17845	COG1012	belongs to the aldehyde dehydrogenase family
C7M16_RS17850	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
C7M16_RS17855	COG1216	Glycosyl transferase, family 2
C7M16_RS17870	COG1695	Transcriptional regulator
C7M16_RS17875	COG0351	phosphomethylpyrimidine kinase
C7M16_RS17885	COG1621	beta-fructofuranosidase activity
C7M16_RS17890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M16_RS17890	COG1263	PTS System
C7M16_RS17895	COG2116	formate transmembrane transporter activity
C7M16_RS17900	COG3711	transcriptional antiterminator
C7M16_RS17910	COG1404	Belongs to the peptidase S8 family
C7M16_RS17915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M16_RS17920	COG0778	Nitroreductase
C7M16_RS17925	COG0772	Belongs to the SEDS family
C7M16_RS17935	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C7M16_RS17940	COG1845	cytochrome c oxidase, subunit III
C7M16_RS17945	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C7M16_RS17950	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C7M16_RS17955	COG2261	transglycosylase associated protein
C7M16_RS17960	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
C7M16_RS17965	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C7M16_RS17970	COG2246	polysaccharide biosynthetic process
C7M16_RS17975	COG1309	transcriptional regulator
C7M16_RS17985	COG3162	membrane
C7M16_RS17990	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M16_RS17995	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C7M16_RS18000	COG2837	iron assimilation
C7M16_RS18005	COG2822	iron ion transport
C7M16_RS18010	COG0672	)-iron permease
C7M16_RS18015	COG0352	thiamine-phosphate diphosphorylase activity
C7M16_RS18020	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
C7M16_RS18025	COG0583	DNA-binding transcription factor activity
C7M16_RS18030	COG1380	Effector of murein hydrolase LrgA
C7M16_RS18035	COG1346	cytolysis
C7M16_RS18040	COG2814	Major facilitator Superfamily
C7M16_RS18045	COG4895	conserved protein (DUF2196)
C7M16_RS18050	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C7M16_RS18055	COG0346	lactoylglutathione lyase activity
C7M16_RS18065	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M16_RS18070	COG1404	Belongs to the peptidase S8 family
C7M16_RS18075	COG1263	PTS System
C7M16_RS18075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M16_RS18080	COG3711	transcriptional antiterminator
C7M16_RS18085	COG1442	glycosyl transferase family 8
C7M16_RS18090	COG5522	Integral membrane protein (intg_mem_TP0381)
C7M16_RS18095	COG1846	Transcriptional regulator
C7M16_RS18100	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C7M16_RS18105	COG2234	aminopeptidase activity
C7M16_RS18120	COG2814	Major facilitator Superfamily
C7M16_RS18125	COG2357	RelA SpoT domain protein
C7M16_RS18130	COG1575	Belongs to the MenA family. Type 1 subfamily
C7M16_RS18145	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M16_RS18150	COG1696	Membrane protein involved in D-alanine export
C7M16_RS18155	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M16_RS18160	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
C7M16_RS18165	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
C7M16_RS18170	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7M16_RS18175	COG1486	melibiose metabolic process
C7M16_RS18180	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7M16_RS18185	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M16_RS18190	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M16_RS18195	COG3711	transcriptional antiterminator
C7M16_RS18195	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M16_RS18205	COG2094	Belongs to the DNA glycosylase MPG family
C7M16_RS18210	COG0753	catalase activity
C7M16_RS18215	COG2814	Major facilitator Superfamily
C7M16_RS18220	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C7M16_RS18225	COG1131	(ABC) transporter
C7M16_RS18245	COG1595	DNA-templated transcription, initiation
C7M16_RS18250	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C7M16_RS18255	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C7M16_RS18260	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C7M16_RS18265	COG4988	ABC transporter
C7M16_RS18270	COG1294	oxidase, subunit
C7M16_RS18275	COG1271	oxidase subunit
C7M16_RS18280	COG3493	citrate carrier protein
C7M16_RS18285	COG0501	Belongs to the peptidase M48B family
C7M16_RS18295	COG0726	polysaccharide deacetylase
C7M16_RS18300	COG3842	ATPase activity
C7M16_RS18305	COG2508	Transcriptional regulator
C7M16_RS18310	COG1012	belongs to the aldehyde dehydrogenase family
C7M16_RS18315	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M16_RS18325	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7M16_RS18335	COG4585	Histidine kinase
C7M16_RS18340	COG2197	response regulator
C7M16_RS18345	COG2195	Cleaves the N-terminal amino acid of tripeptides
C7M16_RS18355	COG4894	glucomannan catabolic process
C7M16_RS18360	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7M16_RS18365	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7M16_RS18370	COG1028	Short-chain dehydrogenase reductase Sdr
C7M16_RS18375	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C7M16_RS18380	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C7M16_RS18385	COG2610	gluconate transmembrane transporter activity
C7M16_RS18390	COG0500	methyltransferase
C7M16_RS18395	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7M16_RS18410	COG0753	catalase activity
C7M16_RS18410	COG0693	protein deglycase activity
C7M16_RS18415	COG2851	Citrate transporter
C7M16_RS18420	COG2273	Hydrolase Family 16
C7M16_RS18425	COG3711	transcriptional antiterminator
C7M16_RS18435	COG2270	Major facilitator Superfamily
C7M16_RS18440	COG0513	Belongs to the DEAD box helicase family
C7M16_RS18445	COG2755	lipolytic protein G-D-S-L family
C7M16_RS18445	COG3401	FG-GAP repeat protein
C7M16_RS18515	COG0697	spore germination
C7M16_RS18520	COG0589	response to stress
C7M16_RS18525	COG2723	6-phospho-beta-galactosidase activity
C7M16_RS18530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M16_RS18530	COG2190	(PTS) system
C7M16_RS18530	COG1263	PTS System
C7M16_RS18540	COG5444	nuclease activity
C7M16_RS18555	COG3507	Belongs to the glycosyl hydrolase 43 family
C7M16_RS18565	COG2986	histidine ammonia-lyase
C7M16_RS18570	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
C7M16_RS18575	COG1228	amidohydrolase
C7M16_RS18580	COG0010	Belongs to the arginase family
C7M16_RS18585	COG0833	amino acid
C7M16_RS18590	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
C7M16_RS18595	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7M16_RS18600	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
C7M16_RS18605	COG2390	Transcriptional regulator
C7M16_RS18615	COG3192	ethanolamine utilization protein
C7M16_RS18620	COG2079	MmgE PrpD family protein
C7M16_RS18630	COG1126	abc transporter atp-binding protein
C7M16_RS18635	COG0765	amino acid transport
C7M16_RS18640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M16_RS18660	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
C7M16_RS18665	COG0561	phosphatase activity
C7M16_RS18695	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M16_RS18700	COG5294	Protein conserved in bacteria
C7M16_RS18705	COG0577	efflux transmembrane transporter activity
C7M16_RS18710	COG1136	(ABC) transporter
C7M16_RS18715	COG2205	protein histidine kinase activity
C7M16_RS18720	COG0745	RESPONSE REGULATOR receiver
C7M16_RS18725	COG0191	fructose-bisphosphate aldolase activity
C7M16_RS18730	COG1082	Xylose isomerase domain protein TIM barrel
C7M16_RS18735	COG1082	Xylose isomerase domain protein TIM barrel
C7M16_RS18740	COG0673	inositol 2-dehydrogenase activity
C7M16_RS18745	COG2814	Major facilitator Superfamily
C7M16_RS18750	COG1082	Xylose isomerase domain protein TIM barrel
C7M16_RS18755	COG3962	Belongs to the TPP enzyme family
C7M16_RS18760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7M16_RS18770	COG1012	belongs to the aldehyde dehydrogenase family
C7M16_RS18775	COG1349	DNA-binding transcription factor activity
C7M16_RS18780	COG0667	Aldo Keto reductase
C7M16_RS18795	COG2814	Major facilitator Superfamily
C7M16_RS18800	COG0326	Molecular chaperone. Has ATPase activity
C7M16_RS18810	COG1028	Short-chain dehydrogenase reductase Sdr
C7M16_RS18815	COG1309	transcriptional regulator
C7M16_RS18820	COG1012	belongs to the aldehyde dehydrogenase family
C7M16_RS18825	COG1714	RDD family
C7M16_RS18830	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C7M16_RS18840	COG1714	RDD family
C7M16_RS18845	COG2311	Membrane
C7M16_RS18850	COG1917	Cupin 2, conserved barrel domain protein
C7M16_RS18855	COG1309	transcriptional regulator
C7M16_RS18860	COG1028	Short-chain dehydrogenase reductase Sdr
C7M16_RS18865	COG1846	Transcriptional regulator
C7M16_RS18870	COG1380	Effector of murein hydrolase LrgA
C7M16_RS18875	COG1346	cytolysis
C7M16_RS18880	COG5039	Polysaccharide pyruvyl transferase
C7M16_RS18885	COG1929	Belongs to the glycerate kinase type-1 family
C7M16_RS18890	COG1802	Transcriptional regulator
C7M16_RS18895	COG1070	Carbohydrate kinase
C7M16_RS18900	COG2610	gluconate transmembrane transporter activity
C7M16_RS18905	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C7M16_RS18910	COG0450	alkyl hydroperoxide reductase
C7M16_RS18915	COG3634	alkyl hydroperoxide reductase activity
C7M16_RS18925	COG2723	6-phospho-beta-galactosidase activity
C7M16_RS18940	COG2188	Transcriptional regulator
C7M16_RS18955	COG1131	(ABC) transporter
C7M16_RS18960	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
C7M16_RS18980	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
C7M16_RS18995	COG1063	alcohol dehydrogenase
C7M16_RS19015	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
C7M16_RS19020	COG0456	acetyltransferase
C7M16_RS19025	COG0457	Tetratricopeptide repeat
C7M16_RS19035	COG0010	Belongs to the arginase family
C7M16_RS19040	COG0833	amino acid
C7M16_RS19045	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C7M16_RS19050	COG3829	transcription factor binding
C7M16_RS19055	COG5002	protein histidine kinase activity
C7M16_RS19080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M16_RS19085	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C7M16_RS19090	COG4853	Protein conserved in bacteria
C7M16_RS19095	COG4863	YycH protein
C7M16_RS19100	COG5002	protein histidine kinase activity
C7M16_RS19105	COG0745	RESPONSE REGULATOR receiver
C7M16_RS19135	COG0346	lactoylglutathione lyase activity
C7M16_RS19140	COG0305	Participates in initiation and elongation during chromosome replication
C7M16_RS19155	COG3093	addiction module antidote protein HigA
C7M16_RS19160	COG2807	transmembrane transport
C7M16_RS19165	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C7M16_RS19170	COG0359	binds to the 23S rRNA
C7M16_RS19175	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
C7M16_RS19180	COG4241	membrane
C7M16_RS19190	COG5577	PFAM Coat F domain
C7M16_RS19195	COG1733	regulation of RNA biosynthetic process
C7M16_RS19200	COG1227	inorganic diphosphatase activity
C7M16_RS19210	COG2271	Major facilitator Superfamily
C7M16_RS19215	COG4978	Transcriptional regulator
C7M16_RS19215	COG0789	Transcriptional regulator
C7M16_RS19225	COG4319	ketosteroid isomerase
C7M16_RS19230	COG1357	PFAM Pentapeptide repeats (8 copies)
C7M16_RS19235	COG2814	Major facilitator Superfamily
C7M16_RS19240	COG0583	DNA-binding transcription factor activity
C7M16_RS19245	COG2153	protein acetylation
C7M16_RS19255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M16_RS19260	COG1846	Transcriptional regulator
C7M16_RS19265	COG2153	protein acetylation
C7M16_RS19270	COG2364	Membrane
C7M16_RS19275	COG0456	acetyltransferase
C7M16_RS19280	COG2315	Protein conserved in bacteria
C7M16_RS19285	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C7M16_RS19295	COG2814	Major facilitator Superfamily
C7M16_RS19305	COG1331	Highly conserved protein containing a thioredoxin domain
C7M16_RS19310	COG0789	Transcriptional regulator
C7M16_RS19315	COG0697	spore germination
C7M16_RS19320	COG1331	Highly conserved protein containing a thioredoxin domain
C7M16_RS19325	COG1266	CAAX protease self-immunity
C7M16_RS19330	COG0477	Major facilitator Superfamily
C7M16_RS19330	COG2814	Major facilitator Superfamily
C7M16_RS19335	COG0110	maltose O-acetyltransferase activity
C7M16_RS19340	COG0346	lactoylglutathione lyase activity
C7M16_RS19345	COG1609	Transcriptional regulator
C7M16_RS19350	COG0708	Exodeoxyribonuclease III
C7M16_RS19355	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C7M16_RS19360	COG0629	single-stranded DNA binding
C7M16_RS19365	COG0360	Binds together with S18 to 16S ribosomal RNA
C7M16_RS19370	COG0012	GTP binding
C7M16_RS19375	COG0243	molybdopterin cofactor binding
C7M16_RS19380	COG4481	Protein conserved in bacteria
C7M16_RS19385	COG3949	Membrane
C7M16_RS19395	COG1475	DNA binding
C7M16_RS19400	COG1192	Involved in chromosome partitioning
C7M16_RS19410	COG1475	DNA binding
C7M16_RS19415	COG0357	Ribosomal RNA small subunit methyltransferase G
C7M16_RS19420	COG0445	tRNA wobble uridine modification
C7M16_RS19425	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C7M16_RS19430	COG1847	R3H domain protein
C7M16_RS19435	COG0706	membrane insertase activity
C7M16_RS19440	COG0594	ribonuclease P activity
C7M16_RS19445	COG0230	Belongs to the bacterial ribosomal protein bL34 family
C7M16_RS19450	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C7M16_RS19455	COG0592	DNA-directed DNA polymerase activity
C7M16_RS19460	COG2501	S4 domain
C7M16_RS19465	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C7M16_RS19475	COG0187	DNA topoisomerase II activity
C7M16_RS19480	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C7M16_RS19515	COG0517	IMP dehydrogenase activity
C7M16_RS19515	COG0516	GMP reductase activity
C7M16_RS19520	COG1686	Belongs to the peptidase S11 family
C7M16_RS19525	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
C7M16_RS19530	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
C7M16_RS19535	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C7M16_RS19545	COG1428	Deoxynucleoside kinase
C7M16_RS19550	COG1428	Deoxynucleoside kinase
C7M16_RS19555	COG3858	chitin binding
C7M16_RS19555	COG1388	LysM domain
C7M16_RS19560	COG1335	isochorismatase
C7M16_RS19565	COG0590	tRNA wobble adenosine to inosine editing
C7M16_RS19575	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C7M16_RS19580	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C7M16_RS19585	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C7M16_RS19630	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
C7M16_RS19635	COG3853	Toxic anion resistance protein (TelA)
C7M16_RS19640	COG1982	Orn Lys Arg decarboxylase major
C7M16_RS19645	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C7M16_RS19650	COG3870	Protein conserved in bacteria
C7M16_RS19655	COG1728	Protein conserved in bacteria
C7M16_RS19660	COG0470	DNA polymerase III
C7M16_RS19665	COG1774	PSP1 C-terminal conserved region
C7M16_RS19670	COG4467	Involved in initiation control of chromosome replication
C7M16_RS19675	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C7M16_RS19680	COG2827	Endonuclease containing a URI domain
C7M16_RS19685	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C7M16_RS19690	COG2002	toxin-antitoxin pair type II binding
C7M16_RS19695	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M16_RS19695	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M16_RS19700	COG0084	hydrolase, TatD family'
C7M16_RS19705	COG3583	domain protein
C7M16_RS19705	COG3584	3D domain protein
C7M16_RS19710	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C7M16_RS19715	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C7M16_RS19725	COG4466	Protein conserved in bacteria
C7M16_RS19735	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
C7M16_RS19740	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7M16_RS19745	COG0251	oxidation-reduction process
C7M16_RS19750	COG2088	sporulation resulting in formation of a cellular spore
C7M16_RS19755	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C7M16_RS19760	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C7M16_RS19765	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
C7M16_RS19770	COG0193	aminoacyl-tRNA hydrolase activity
C7M16_RS19780	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C7M16_RS19785	COG2002	toxin-antitoxin pair type II binding
C7M16_RS19790	COG2244	polysaccharide biosynthetic process
C7M16_RS19795	COG3956	TIGRFAM MazG family protein
C7M16_RS19800	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C7M16_RS19815	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
C7M16_RS19820	COG1098	S1 RNA binding domain
C7M16_RS19835	COG2208	phosphoserine phosphatase activity
C7M16_RS19840	COG2304	oxidoreductase activity
C7M16_RS19845	COG0515	serine threonine protein kinase
C7M16_RS19850	COG0037	tRNA processing
C7M16_RS19860	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C7M16_RS19865	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
C7M16_RS19870	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C7M16_RS19875	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C7M16_RS19880	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7M16_RS19885	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C7M16_RS19890	COG0512	Glutamine amidotransferase of anthranilate synthase
C7M16_RS19895	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7M16_RS19900	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C7M16_RS19905	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C7M16_RS19910	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C7M16_RS19915	COG1396	sequence-specific DNA binding
C7M16_RS19920	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7M16_RS19925	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C7M16_RS20005	COG4463	regulation of RNA biosynthetic process
C7M16_RS20010	COG3880	PFAM UvrB UvrC protein
C7M16_RS20015	COG3869	Catalyzes the specific phosphorylation of arginine residues in
C7M16_RS20020	COG0542	response to heat
C7M16_RS20025	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C7M16_RS20030	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
C7M16_RS20035	COG4956	integral membrane protein (PIN domain superfamily)
C7M16_RS20040	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
C7M16_RS20045	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
C7M16_RS20050	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C7M16_RS20055	COG1045	serine acetyltransferase
C7M16_RS20060	COG0215	cysteine-tRNA ligase activity
C7M16_RS20065	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
C7M16_RS20070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7M16_RS20075	COG3688	RNA-binding protein containing a PIN domain
C7M16_RS20080	COG1595	DNA-templated transcription, initiation
C7M16_RS20085	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C7M16_RS20090	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C7M16_RS20095	COG0250	Participates in transcription elongation, termination and antitermination
C7M16_RS20100	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
C7M16_RS20105	COG0081	regulation of translation
C7M16_RS20110	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C7M16_RS20115	COG0222	ribosome binding
C7M16_RS20120	COG2813	Specifically methylates the guanine in position
C7M16_RS20125	COG0085	RNA polymerase activity
C7M16_RS20130	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C7M16_RS20135	COG1358	cellular component organization or biogenesis
C7M16_RS20140	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C7M16_RS20145	COG0049	tRNA binding
C7M16_RS20150	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C7M16_RS20155	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C7M16_RS20160	COG0596	Alpha beta hydrolase
C7M16_RS20165	COG0051	transcription antitermination factor activity, RNA binding
C7M16_RS20170	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C7M16_RS20175	COG0088	Forms part of the polypeptide exit tunnel
C7M16_RS20180	COG0089	rRNA binding
C7M16_RS20185	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C7M16_RS20190	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C7M16_RS20195	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
C7M16_RS20200	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
C7M16_RS20205	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
C7M16_RS20210	COG0255	Belongs to the universal ribosomal protein uL29 family
C7M16_RS20215	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
C7M16_RS20220	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
C7M16_RS20230	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C7M16_RS20240	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
C7M16_RS20245	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
C7M16_RS20250	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
C7M16_RS20255	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
C7M16_RS20260	COG1841	ribosomal large subunit assembly
C7M16_RS20265	COG0200	Binds to the 23S rRNA
C7M16_RS20270	COG0201	protein transport
C7M16_RS20275	COG0563	adenylate kinase activity
C7M16_RS20280	COG0024	Methionine aminopeptidase
C7M16_RS20290	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C7M16_RS20295	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C7M16_RS20300	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C7M16_RS20305	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C7M16_RS20310	COG0202	RNA polymerase activity
C7M16_RS20315	COG0203	ribosomal protein L17
C7M16_RS20320	COG1122	ATPase activity
C7M16_RS20325	COG1122	ATPase activity
C7M16_RS20330	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C7M16_RS20335	COG0101	tRNA pseudouridine synthase activity
C7M16_RS20340	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C7M16_RS20345	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C7M16_RS20350	COG2226	methyltransferase
C7M16_RS20360	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M16_RS20365	COG0489	protein tyrosine kinase activity
C7M16_RS20375	COG2194	sulfuric ester hydrolase activity
C7M16_RS20380	COG0726	polysaccharide deacetylase
C7M16_RS20460	COG0659	secondary active sulfate transmembrane transporter activity
C7M16_RS20465	COG0385	Bile acid
C7M16_RS20470	COG2819	hydrolase of the alpha beta superfamily
C7M16_RS20475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M16_RS20480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M16_RS20485	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M16_RS20490	COG2207	Transcriptional regulator
C7M16_RS20490	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M16_RS20495	COG3876	Protein conserved in bacteria