locus-tag	class	description
ETL58_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ETL58_RS00010	COG0592	DNA-directed DNA polymerase activity
ETL58_RS00015	COG2501	S4 domain
ETL58_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ETL58_RS00030	COG0187	DNA topoisomerase II activity
ETL58_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ETL58_RS00070	COG0516	GMP reductase activity
ETL58_RS00070	COG0517	IMP dehydrogenase activity
ETL58_RS00075	COG1686	Belongs to the peptidase S11 family
ETL58_RS00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ETL58_RS00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ETL58_RS00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ETL58_RS00100	COG1428	Deoxynucleoside kinase
ETL58_RS00105	COG1428	Deoxynucleoside kinase
ETL58_RS00110	COG1388	LysM domain
ETL58_RS00110	COG3858	chitin binding
ETL58_RS00115	COG1335	isochorismatase
ETL58_RS00120	COG0590	tRNA wobble adenosine to inosine editing
ETL58_RS00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ETL58_RS00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ETL58_RS00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ETL58_RS00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
ETL58_RS00190	COG3853	Toxic anion resistance protein (TelA)
ETL58_RS00195	COG1982	Orn Lys Arg decarboxylase major
ETL58_RS00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ETL58_RS00205	COG3870	Protein conserved in bacteria
ETL58_RS00210	COG1728	Protein conserved in bacteria
ETL58_RS00215	COG0470	DNA polymerase III
ETL58_RS00220	COG1774	PSP1 C-terminal conserved region
ETL58_RS00225	COG4467	Involved in initiation control of chromosome replication
ETL58_RS00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ETL58_RS00235	COG2827	Endonuclease containing a URI domain
ETL58_RS00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ETL58_RS00245	COG2002	toxin-antitoxin pair type II binding
ETL58_RS00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ETL58_RS00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ETL58_RS00255	COG0084	hydrolase, TatD family'
ETL58_RS00260	COG3583	domain protein
ETL58_RS00260	COG3584	3D domain protein
ETL58_RS00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ETL58_RS00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ETL58_RS00280	COG4466	Protein conserved in bacteria
ETL58_RS00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ETL58_RS00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ETL58_RS00300	COG0251	oxidation-reduction process
ETL58_RS00305	COG2088	sporulation resulting in formation of a cellular spore
ETL58_RS00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ETL58_RS00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ETL58_RS00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ETL58_RS00325	COG0193	aminoacyl-tRNA hydrolase activity
ETL58_RS00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ETL58_RS00340	COG2002	toxin-antitoxin pair type II binding
ETL58_RS00345	COG2244	polysaccharide biosynthetic process
ETL58_RS00350	COG3956	TIGRFAM MazG family protein
ETL58_RS00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ETL58_RS00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ETL58_RS00375	COG1098	S1 RNA binding domain
ETL58_RS00390	COG2208	phosphoserine phosphatase activity
ETL58_RS00395	COG2304	oxidoreductase activity
ETL58_RS00400	COG0515	serine threonine protein kinase
ETL58_RS00405	COG0037	tRNA processing
ETL58_RS00410	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ETL58_RS00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ETL58_RS00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ETL58_RS00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ETL58_RS00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ETL58_RS00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ETL58_RS00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ETL58_RS00445	COG0512	Glutamine amidotransferase of anthranilate synthase
ETL58_RS00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ETL58_RS00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ETL58_RS00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ETL58_RS00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ETL58_RS00470	COG1396	sequence-specific DNA binding
ETL58_RS00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ETL58_RS00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ETL58_RS00560	COG4463	regulation of RNA biosynthetic process
ETL58_RS00565	COG3880	PFAM UvrB UvrC protein
ETL58_RS00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
ETL58_RS00575	COG0542	response to heat
ETL58_RS00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ETL58_RS00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
ETL58_RS00590	COG4956	integral membrane protein (PIN domain superfamily)
ETL58_RS00595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ETL58_RS00600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ETL58_RS00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ETL58_RS00615	COG1045	serine acetyltransferase
ETL58_RS00620	COG0215	cysteine-tRNA ligase activity
ETL58_RS00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
ETL58_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ETL58_RS00635	COG3688	RNA-binding protein containing a PIN domain
ETL58_RS00640	COG1595	DNA-templated transcription, initiation
ETL58_RS00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ETL58_RS00655	COG0250	Participates in transcription elongation, termination and antitermination
ETL58_RS00665	COG0081	regulation of translation
ETL58_RS00670	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ETL58_RS00680	COG2813	Specifically methylates the guanine in position
ETL58_RS00685	COG0085	RNA polymerase activity
ETL58_RS00690	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ETL58_RS00695	COG1358	cellular component organization or biogenesis
ETL58_RS00700	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ETL58_RS00705	COG0049	tRNA binding
ETL58_RS00710	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ETL58_RS00715	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ETL58_RS00720	COG0596	Alpha beta hydrolase
ETL58_RS00730	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ETL58_RS00735	COG0088	Forms part of the polypeptide exit tunnel
ETL58_RS00745	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ETL58_RS00765	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ETL58_RS00775	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ETL58_RS00780	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ETL58_RS00790	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ETL58_RS00800	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ETL58_RS00805	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ETL58_RS00810	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ETL58_RS00815	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ETL58_RS00825	COG0200	Binds to the 23S rRNA
ETL58_RS00830	COG0201	protein transport
ETL58_RS00835	COG0563	adenylate kinase activity
ETL58_RS00840	COG0024	Methionine aminopeptidase
ETL58_RS00845	COG2163	COG2163 Ribosomal protein L14E L6E L27E
ETL58_RS00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ETL58_RS00860	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ETL58_RS00865	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ETL58_RS00870	COG0202	RNA polymerase activity
ETL58_RS00875	COG0203	ribosomal protein L17
ETL58_RS00880	COG1122	ATPase activity
ETL58_RS00885	COG1122	ATPase activity
ETL58_RS00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ETL58_RS00895	COG0101	tRNA pseudouridine synthase activity
ETL58_RS00900	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ETL58_RS00905	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ETL58_RS00910	COG2226	methyltransferase
ETL58_RS00920	COG0860	N-Acetylmuramoyl-L-alanine amidase
ETL58_RS00925	COG0489	protein tyrosine kinase activity
ETL58_RS00935	COG2194	sulfuric ester hydrolase activity
ETL58_RS00940	COG0726	polysaccharide deacetylase
ETL58_RS01115	COG0659	secondary active sulfate transmembrane transporter activity
ETL58_RS01120	COG0385	Bile acid
ETL58_RS01125	COG2819	hydrolase of the alpha beta superfamily
ETL58_RS01130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETL58_RS01135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETL58_RS01140	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ETL58_RS01145	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ETL58_RS01145	COG2207	Transcriptional regulator
ETL58_RS01150	COG3876	Protein conserved in bacteria
ETL58_RS01155	COG1472	Belongs to the glycosyl hydrolase 3 family
ETL58_RS01160	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ETL58_RS01165	COG1263	PTS System
ETL58_RS01165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETL58_RS01170	COG1737	Transcriptional regulator
ETL58_RS01175	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ETL58_RS01180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ETL58_RS01185	COG1683	Conserved Protein
ETL58_RS01215	COG1595	DNA-templated transcription, initiation
ETL58_RS01220	COG5662	AntiSigma factor
ETL58_RS01225	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ETL58_RS01230	COG4856	YbbR-like protein
ETL58_RS01235	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ETL58_RS01240	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ETL58_RS01250	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ETL58_RS01255	COG2169	Transcriptional regulator
ETL58_RS01260	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ETL58_RS01265	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ETL58_RS01270	COG3002	Belongs to the UPF0753 family
ETL58_RS01275	COG0288	reversible hydration of carbon dioxide
ETL58_RS01285	COG5609	conserved protein (DUF2294)
ETL58_RS01290	COG0640	Transcriptional regulator
ETL58_RS01295	COG2814	Major facilitator Superfamily
ETL58_RS01310	COG0596	Alpha beta hydrolase
ETL58_RS01315	COG0745	RESPONSE REGULATOR receiver
ETL58_RS01320	COG0642	Histidine kinase
ETL58_RS01330	COG0515	serine threonine protein kinase
ETL58_RS01345	COG1113	amino acid transport
ETL58_RS01365	COG2124	cytochrome p450
ETL58_RS01375	COG0531	amino acid
ETL58_RS01380	COG0584	glycerophosphoryl diester phosphodiesterase
ETL58_RS01385	COG2271	Major facilitator Superfamily
ETL58_RS01400	COG0456	acetyltransferase
ETL58_RS01400	COG1846	Transcriptional regulator
ETL58_RS01405	COG2271	Major facilitator Superfamily
ETL58_RS01415	COG3409	Peptidoglycan-binding domain 1 protein
ETL58_RS01420	COG0697	spore germination
ETL58_RS01425	COG2207	Transcriptional regulator
ETL58_RS01425	COG1917	Cupin 2, conserved barrel domain protein
ETL58_RS01430	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ETL58_RS01435	COG3591	Belongs to the peptidase S1B family
ETL58_RS01445	COG0596	Alpha beta hydrolase
ETL58_RS01450	COG1183	phosphatidylcholine synthase activity
ETL58_RS01455	COG0586	Pfam SNARE associated Golgi protein
ETL58_RS01460	COG0688	phosphatidylethanolamine metabolic process
ETL58_RS01470	COG1054	Belongs to the UPF0176 family
ETL58_RS01475	COG1301	dicarboxylic acid transport
ETL58_RS01480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETL58_RS01480	COG1263	PTS System
ETL58_RS01480	COG2190	(PTS) system
ETL58_RS01485	COG0363	glucosamine-6-phosphate deaminase activity
ETL58_RS01490	COG2188	Transcriptional regulator
ETL58_RS01500	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ETL58_RS01505	COG0833	amino acid
ETL58_RS01510	COG2040	homocysteine
ETL58_RS01520	COG1115	amino acid carrier protein
ETL58_RS01525	COG2066	Belongs to the glutaminase family
ETL58_RS01530	COG4191	Histidine kinase
ETL58_RS01535	COG0784	Response regulator, receiver
ETL58_RS01545	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ETL58_RS01550	COG1012	belongs to the aldehyde dehydrogenase family
ETL58_RS01555	COG2271	Major facilitator Superfamily
ETL58_RS01560	COG4948	Mandelate Racemase Muconate Lactonizing
ETL58_RS01565	COG2186	Transcriptional regulator
ETL58_RS01570	COG2721	sulfolactate sulfo-lyase activity
ETL58_RS01575	COG3173	Aminoglycoside phosphotransferase
ETL58_RS01590	COG0745	RESPONSE REGULATOR receiver
ETL58_RS01595	COG2205	protein histidine kinase activity
ETL58_RS01600	COG1131	(ABC) transporter
ETL58_RS01620	COG3773	Cell wall hydrolase
ETL58_RS01625	COG2304	oxidoreductase activity
ETL58_RS01635	COG3540	Alkaline phosphatase
ETL58_RS01640	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ETL58_RS01645	COG0805	protein transport
ETL58_RS01650	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
ETL58_RS01655	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ETL58_RS01660	COG0477	Major facilitator Superfamily
ETL58_RS01665	COG1309	transcriptional regulator
ETL58_RS01670	COG0252	asparaginase activity
ETL58_RS01675	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
ETL58_RS01680	COG1714	RDD family
ETL58_RS01685	COG1405	negative regulation of cell septum assembly
ETL58_RS01685	COG3012	SEC-C Motif Domain Protein
ETL58_RS01690	COG3290	protein histidine kinase activity
ETL58_RS01695	COG3279	Response regulator of the LytR AlgR family
ETL58_RS01700	COG4555	ABC transporter
ETL58_RS01705	COG1668	transmembrane transport
ETL58_RS01725	COG1595	DNA-templated transcription, initiation
ETL58_RS01730	COG1595	DNA-templated transcription, initiation
ETL58_RS01735	COG1876	peptidase activity
ETL58_RS01740	COG0457	Tetratricopeptide repeat
ETL58_RS01745	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_RS01750	COG0366	Alpha amylase catalytic
ETL58_RS01755	COG0803	Belongs to the bacterial solute-binding protein 9 family
ETL58_RS01760	COG1121	(ABC) transporter
ETL58_RS01765	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ETL58_RS01770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ETL58_RS01775	COG2310	stress, protein
ETL58_RS01780	COG2310	stress, protein
ETL58_RS01785	COG2310	stress, protein
ETL58_RS01790	COG0861	Integral membrane protein TerC family
ETL58_RS01800	COG3853	Toxic anion resistance protein (TelA)
ETL58_RS01805	COG0477	Major facilitator Superfamily
ETL58_RS01815	COG2814	Major facilitator Superfamily
ETL58_RS01820	COG0640	Transcriptional regulator
ETL58_RS01825	COG0517	IMP dehydrogenase activity
ETL58_RS01825	COG4175	Glycine betaine
ETL58_RS01830	COG4176	ABC-type proline glycine betaine transport system permease component
ETL58_RS01835	COG2113	Glycine betaine
ETL58_RS01840	COG1473	amidohydrolase
ETL58_RS01845	COG1288	antiporter activity
ETL58_RS01855	COG0366	Alpha amylase catalytic
ETL58_RS01860	COG0039	L-malate dehydrogenase activity
ETL58_RS01865	COG1620	l-lactate permease
ETL58_RS01870	COG2814	Major facilitator Superfamily
ETL58_RS01875	COG1846	Transcriptional regulator
ETL58_RS01880	COG1280	lysine exporter protein (LysE YggA)
ETL58_RS01885	COG3403	YqcI/YcgG family
ETL58_RS01890	COG1113	amino acid transport
ETL58_RS01895	COG3665	Urea carboxylase-associated protein
ETL58_RS01900	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ETL58_RS01905	COG1660	Displays ATPase and GTPase activities
ETL58_RS01910	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ETL58_RS01915	COG2226	methyltransferase
ETL58_RS01920	COG0583	DNA-binding transcription factor activity
ETL58_RS01925	COG3458	cephalosporin-C deacetylase activity
ETL58_RS01930	COG3541	Predicted nucleotidyltransferase
ETL58_RS01935	COG0506	proline dehydrogenase activity
ETL58_RS01940	COG1012	belongs to the aldehyde dehydrogenase family
ETL58_RS01945	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ETL58_RS01950	COG2508	Transcriptional regulator
ETL58_RS01955	COG3689	TIGRFAM TIGR03943 family protein
ETL58_RS01960	COG0701	Predicted permease
ETL58_RS01965	COG2267	carboxylic ester hydrolase activity
ETL58_RS01970	COG0492	ferredoxin-NADP+ reductase activity
ETL58_RS01975	COG1587	Uroporphyrinogen-III synthase
ETL58_RS01975	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ETL58_RS01980	COG2146	nitrite reductase [NAD(P)H] activity
ETL58_RS01985	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ETL58_RS01990	COG0243	molybdopterin cofactor binding
ETL58_RS01995	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ETL58_RS02000	COG2223	nitrite transmembrane transporter activity
ETL58_RS02005	COG1469	GTP cyclohydrolase I activity
ETL58_RS02010	COG1376	ErfK ybiS ycfS ynhG family protein
ETL58_RS02020	COG0523	cobalamin synthesis protein
ETL58_RS02025	COG0765	amino acid transport
ETL58_RS02030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETL58_RS02040	COG1714	RDD family
ETL58_RS02050	COG2723	6-phospho-beta-galactosidase activity
ETL58_RS02060	COG3209	COG3209 Rhs family protein
ETL58_RS02065	COG0840	transmembrane signaling receptor activity
ETL58_RS02065	COG3290	protein histidine kinase activity
ETL58_RS02070	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ETL58_RS02075	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ETL58_RS02080	COG1733	regulation of RNA biosynthetic process
ETL58_RS02085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETL58_RS02090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETL58_RS02095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETL58_RS02100	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
ETL58_RS02105	COG2814	Major facilitator Superfamily
ETL58_RS02115	COG0697	spore germination
ETL58_RS02120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ETL58_RS02130	COG2364	Membrane
ETL58_RS02140	COG1126	abc transporter atp-binding protein
ETL58_RS02145	COG0765	amino acid transport
ETL58_RS02150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETL58_RS02155	COG0583	DNA-binding transcription factor activity
ETL58_RS02160	COG0163	prenyltransferase activity
ETL58_RS02165	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ETL58_RS02180	COG0596	Alpha beta hydrolase
ETL58_RS02185	COG3104	oligopeptide transport
ETL58_RS02190	COG5434	Belongs to the glycosyl hydrolase 28 family
ETL58_RS02200	COG0697	spore germination
ETL58_RS02210	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ETL58_RS02215	COG1136	(ABC) transporter
ETL58_RS02220	COG0577	efflux transmembrane transporter activity
ETL58_RS02225	COG0745	RESPONSE REGULATOR receiver
ETL58_RS02230	COG3850	Histidine kinase
ETL58_RS02230	COG5002	protein histidine kinase activity
ETL58_RS02235	COG0457	Tetratricopeptide repeat
ETL58_RS02255	COG0527	aspartate kinase activity
ETL58_RS02260	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETL58_RS02265	COG4605	iron ion homeostasis
ETL58_RS02270	COG4604	ABC transporter, ATP-binding protein
ETL58_RS02275	COG4607	ABC-type enterochelin transport system periplasmic component
ETL58_RS02280	COG2814	Major facilitator Superfamily
ETL58_RS02285	COG1309	transcriptional regulator
ETL58_RS02290	COG0778	Nitroreductase
ETL58_RS02295	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ETL58_RS02300	COG0640	Transcriptional regulator
ETL58_RS02305	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ETL58_RS02310	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ETL58_RS02315	COG1012	belongs to the aldehyde dehydrogenase family
ETL58_RS02320	COG4975	Glucose uptake
ETL58_RS02325	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_RS02330	COG4549	nuclear export factor GLE1
ETL58_RS02335	COG2372	response to copper ion
ETL58_RS02335	COG1276	copper resistance
ETL58_RS02340	COG1349	DNA-binding transcription factor activity
ETL58_RS02350	COG2213	PTS system mannitol-specific
ETL58_RS02355	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETL58_RS02360	COG0246	Mannitol dehydrogenase
ETL58_RS02365	COG0473	3-isopropylmalate dehydrogenase activity
ETL58_RS02370	COG0681	Belongs to the peptidase S26 family
ETL58_RS02375	COG0412	Dienelactone hydrolase
ETL58_RS02380	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ETL58_RS02390	COG0561	phosphatase activity
ETL58_RS02395	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ETL58_RS02400	COG1914	H( )-stimulated, divalent metal cation uptake system
ETL58_RS02405	COG4336	lyase activity
ETL58_RS02410	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ETL58_RS02415	COG1984	allophanate hydrolase subunit 2
ETL58_RS02420	COG1414	Transcriptional regulator
ETL58_RS02425	COG2755	lipolytic protein G-D-S-L family
ETL58_RS02435	COG2329	Antibiotic biosynthesis monooxygenase
ETL58_RS02440	COG0768	penicillin binding
ETL58_RS02445	COG4989	oxidoreductase activity
ETL58_RS02450	COG3711	transcriptional antiterminator
ETL58_RS02455	COG0318	PFAM AMP-dependent synthetase and ligase
ETL58_RS02460	COG2226	methyltransferase
ETL58_RS02465	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_RS02470	COG1917	Cupin 2, conserved barrel domain protein
ETL58_RS02475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ETL58_RS02480	COG3871	stress protein (general stress protein 26)
ETL58_RS02490	COG2814	Major facilitator Superfamily
ETL58_RS02495	COG1522	sequence-specific DNA binding
ETL58_RS02500	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ETL58_RS02500	COG0551	DNA topoisomerase type I activity
ETL58_RS02505	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
ETL58_RS02510	COG3706	GGDEF domain
ETL58_RS02515	COG5298	Protein conserved in bacteria
ETL58_RS02520	COG1215	transferase activity, transferring glycosyl groups
ETL58_RS02530	COG0531	amino acid
ETL58_RS02535	COG0494	nUDIX hydrolase
ETL58_RS02540	COG0028	Belongs to the TPP enzyme family
ETL58_RS02550	COG1914	H( )-stimulated, divalent metal cation uptake system
ETL58_RS02555	COG2261	transglycosylase associated protein
ETL58_RS02560	COG4876	unkown
ETL58_RS02565	COG2217	Heavy metal translocating P-type atpase
ETL58_RS02570	COG3729	General stress protein
ETL58_RS02575	COG0662	Cupin 2, conserved barrel domain protein
ETL58_RS02580	COG2329	Antibiotic biosynthesis monooxygenase
ETL58_RS02585	COG3546	catalase activity
ETL58_RS02590	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ETL58_RS02595	COG3290	protein histidine kinase activity
ETL58_RS02600	COG4565	transcriptional regulatory protein
ETL58_RS02605	COG1301	dicarboxylic acid transport
ETL58_RS02610	COG0628	permease
ETL58_RS02615	COG1131	(ABC) transporter
ETL58_RS02620	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
ETL58_RS02630	COG1960	acyl-CoA dehydrogenase activity
ETL58_RS02645	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ETL58_RS02650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETL58_RS02655	COG1181	Belongs to the D-alanine--D-alanine ligase family
ETL58_RS02660	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ETL58_RS02670	COG0513	Belongs to the DEAD box helicase family
ETL58_RS02675	COG3402	PFAM membrane-flanked domain
ETL58_RS02680	COG3428	Bacterial PH domain
ETL58_RS02685	COG0705	Rhomboid family
ETL58_RS02690	COG0736	holo-[acyl-carrier-protein] synthase activity
ETL58_RS02695	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ETL58_RS02700	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ETL58_RS02705	COG0864	Transcriptional regulator
ETL58_RS02710	COG2337	Toxic component of a toxin-antitoxin (TA) module
ETL58_RS02715	COG1366	Belongs to the anti-sigma-factor antagonist family
ETL58_RS02720	COG1366	Belongs to the anti-sigma-factor antagonist family
ETL58_RS02725	COG2172	sigma factor antagonist activity
ETL58_RS02730	COG2208	phosphoserine phosphatase activity
ETL58_RS02735	COG1366	Belongs to the anti-sigma-factor antagonist family
ETL58_RS02740	COG2172	sigma factor antagonist activity
ETL58_RS02745	COG1191	sigma factor activity
ETL58_RS02750	COG2208	phosphoserine phosphatase activity
ETL58_RS02755	COG2183	response to ionizing radiation
ETL58_RS02765	COG3091	SprT-like family
ETL58_RS02815	COG0515	serine threonine protein kinase
ETL58_RS02825	COG0515	serine threonine protein kinase
ETL58_RS02830	COG1132	(ABC) transporter
ETL58_RS02845	COG1476	TRANSCRIPTIONal
ETL58_RS02855	COG3239	Fatty acid desaturase
ETL58_RS02860	COG1278	Cold shock
ETL58_RS02865	COG1329	Transcriptional regulator
ETL58_RS02875	COG0697	spore germination
ETL58_RS02880	COG2207	Transcriptional regulator
ETL58_RS02880	COG1917	Cupin 2, conserved barrel domain protein
ETL58_RS02885	COG0697	spore germination
ETL58_RS02890	COG2207	Transcriptional regulator
ETL58_RS02890	COG3708	Transcriptional regulator
ETL58_RS02895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ETL58_RS02900	COG0477	Major facilitator Superfamily
ETL58_RS02910	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
ETL58_RS02925	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETL58_RS02930	COG1309	transcriptional regulator
ETL58_RS02940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ETL58_RS02945	COG2030	dehydratase
ETL58_RS02950	COG3545	Serine hydrolase
ETL58_RS02955	COG1733	regulation of RNA biosynthetic process
ETL58_RS02960	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETL58_RS02965	COG1733	regulation of RNA biosynthetic process
ETL58_RS02970	COG2249	NAD(P)H dehydrogenase (quinone) activity
ETL58_RS02975	COG2814	Major facilitator Superfamily
ETL58_RS02980	COG1309	transcriptional regulator
ETL58_RS02985	COG0640	Transcriptional regulator
ETL58_RS02990	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ETL58_RS03000	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ETL58_RS03005	COG0697	spore germination
ETL58_RS03010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ETL58_RS03015	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ETL58_RS03020	COG0640	Transcriptional regulator
ETL58_RS03025	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ETL58_RS03040	COG4585	Histidine kinase
ETL58_RS03045	COG2197	response regulator
ETL58_RS03050	COG2409	Drug exporters of the RND superfamily
ETL58_RS03055	COG0596	Alpha beta hydrolase
ETL58_RS03060	COG1811	Na channel or pump
ETL58_RS03065	COG0789	Transcriptional regulator
ETL58_RS03065	COG4978	Transcriptional regulator
ETL58_RS03070	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ETL58_RS03075	COG0778	Nitroreductase
ETL58_RS03080	COG0346	lactoylglutathione lyase activity
ETL58_RS03085	COG2259	Doxx family
ETL58_RS03090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETL58_RS03110	COG2323	membrane
ETL58_RS03115	COG2323	membrane
ETL58_RS03120	COG0071	Belongs to the small heat shock protein (HSP20) family
ETL58_RS03135	COG1309	transcriptional regulator
ETL58_RS03145	COG0456	acetyltransferase
ETL58_RS03150	COG0488	(ABC) transporter
ETL58_RS03155	COG1113	amino acid transport
ETL58_RS03160	COG2318	DinB family
ETL58_RS03165	COG1846	Transcriptional regulator
ETL58_RS03170	COG1033	growth of symbiont in host cell
ETL58_RS03170	COG2409	Drug exporters of the RND superfamily
ETL58_RS03175	COG0778	Nitroreductase
ETL58_RS03180	COG1846	Transcriptional regulator
ETL58_RS03185	COG2814	Major facilitator Superfamily
ETL58_RS03190	COG0730	response to heat
ETL58_RS03195	COG1802	Transcriptional regulator
ETL58_RS03200	COG1388	LysM domain
ETL58_RS03200	COG3858	chitin binding
ETL58_RS03205	COG1819	glycosyl
ETL58_RS03215	COG1785	Belongs to the alkaline phosphatase family
ETL58_RS03220	COG5646	InterPro IPR014922
ETL58_RS03230	COG0454	-acetyltransferase
ETL58_RS03235	COG1078	dGTPase activity
ETL58_RS03240	COG1388	LysM domain
ETL58_RS03245	COG2814	Major facilitator Superfamily
ETL58_RS03250	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETL58_RS03255	COG1447	Phosphotransferase system cellobiose-specific component IIA
ETL58_RS03260	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETL58_RS03265	COG2723	6-phospho-beta-galactosidase activity
ETL58_RS03270	COG2188	Transcriptional regulator
ETL58_RS03275	COG1940	carbohydrate kinase activity
ETL58_RS03280	COG1482	cell wall glycoprotein biosynthetic process
ETL58_RS03285	COG4124	Belongs to the glycosyl hydrolase 26 family
ETL58_RS03330	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ETL58_RS03335	COG0802	atpase or kinase
ETL58_RS03340	COG1214	PFAM Peptidase M22, glycoprotease
ETL58_RS03345	COG0456	acetyltransferase
ETL58_RS03350	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ETL58_RS03355	COG0488	(ABC) transporter
ETL58_RS03360	COG0315	cyclic pyranopterin monophosphate synthase activity
ETL58_RS03365	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ETL58_RS03370	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ETL58_RS03375	COG0805	protein transport
ETL58_RS03390	COG1266	CAAX protease self-immunity
ETL58_RS03400	COG0459	protein refolding
ETL58_RS03405	COG4974	Belongs to the 'phage' integrase family
ETL58_RS03410	COG2856	Zn peptidase
ETL58_RS03425	COG1396	sequence-specific DNA binding
ETL58_RS03475	COG5377	YqaJ viral recombinase family
ETL58_RS03480	COG3723	Recombinational DNA repair protein, rece pathway
ETL58_RS03485	COG3935	DnaD domain protein
ETL58_RS03490	COG1484	DNA-dependent DNA replication
ETL58_RS03570	COG3677	Transposase
ETL58_RS03580	COG5484	DNA packaging
ETL58_RS03585	COG1783	phage Terminase large subunit
ETL58_RS03705	COG3409	Peptidoglycan-binding domain 1 protein
ETL58_RS03705	COG5632	N-Acetylmuramoyl-L-alanine amidase
ETL58_RS03705	COG1388	LysM domain
ETL58_RS03745	COG1073	alpha beta
ETL58_RS03750	COG0457	Tetratricopeptide repeat
ETL58_RS03755	COG1063	alcohol dehydrogenase
ETL58_RS03760	COG2211	Major facilitator Superfamily
ETL58_RS03765	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ETL58_RS03770	COG1842	Phage shock protein A
ETL58_RS03775	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ETL58_RS03780	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ETL58_RS03785	COG4260	virion core protein, lumpy skin disease virus
ETL58_RS03795	COG2814	Major facilitator Superfamily
ETL58_RS03800	COG1063	alcohol dehydrogenase
ETL58_RS03805	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ETL58_RS03810	COG0823	Involved in the tonB-independent uptake of proteins
ETL58_RS03825	COG2267	carboxylic ester hydrolase activity
ETL58_RS03835	COG2132	Multicopper oxidase
ETL58_RS03840	COG1113	amino acid transport
ETL58_RS03850	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ETL58_RS03855	COG0714	Associated with various cellular activities
ETL58_RS03860	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
ETL58_RS03865	COG1305	Transglutaminase-like
ETL58_RS03870	COG0519	Catalyzes the synthesis of GMP from XMP
ETL58_RS03870	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ETL58_RS03885	COG2252	PERMEase
ETL58_RS03890	COG3064	Membrane
ETL58_RS03900	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
ETL58_RS03910	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ETL58_RS03915	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ETL58_RS03920	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ETL58_RS03925	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ETL58_RS03930	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ETL58_RS03935	COG0047	phosphoribosylformylglycinamidine synthase activity
ETL58_RS03940	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ETL58_RS03945	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ETL58_RS03950	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ETL58_RS03955	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ETL58_RS03960	COG0138	bifunctional purine biosynthesis protein purh
ETL58_RS03965	COG0151	Belongs to the GarS family
ETL58_RS03970	COG1522	sequence-specific DNA binding
ETL58_RS03975	COG0531	amino acid
ETL58_RS03985	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ETL58_RS03990	COG1470	cell adhesion involved in biofilm formation
ETL58_RS03995	COG4496	protein, YerC YecD
ETL58_RS04000	COG0069	glutamate synthase activity
ETL58_RS04005	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
ETL58_RS04010	COG0210	DNA helicase
ETL58_RS04015	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ETL58_RS04020	COG4851	CamS sex pheromone cAM373 precursor
ETL58_RS04025	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ETL58_RS04030	COG1285	pathogenesis
ETL58_RS04035	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ETL58_RS04040	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ETL58_RS04045	COG0154	amidase activity
ETL58_RS04050	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ETL58_RS04055	COG1309	transcriptional regulator
ETL58_RS04060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ETL58_RS04065	COG1597	lipid kinase activity
ETL58_RS04070	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ETL58_RS04095	COG0457	Tetratricopeptide repeat
ETL58_RS04110	COG5444	nuclease activity
ETL58_RS04115	COG3391	amine dehydrogenase activity
ETL58_RS04125	COG0457	Tetratricopeptide repeat
ETL58_RS04135	COG0217	transcriptional regulatory protein
ETL58_RS04145	COG1309	transcriptional regulator
ETL58_RS04150	COG3631	Ketosteroid isomerase-related protein
ETL58_RS04155	COG0702	epimerase
ETL58_RS04170	COG3546	catalase activity
ETL58_RS04175	COG0454	-acetyltransferase
ETL58_RS04185	COG5578	integral membrane protein
ETL58_RS04190	COG2972	Histidine kinase
ETL58_RS04195	COG4753	response regulator
ETL58_RS04195	COG2207	Transcriptional regulator
ETL58_RS04200	COG1653	transport
ETL58_RS04205	COG1175	transmembrane transport
ETL58_RS04210	COG0395	ABC-type sugar transport system, permease component
ETL58_RS04215	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
ETL58_RS04220	COG2207	Transcriptional regulator
ETL58_RS04225	COG2755	lipolytic protein G-D-S-L family
ETL58_RS04235	COG5578	integral membrane protein
ETL58_RS04240	COG3401	FG-GAP repeat protein
ETL58_RS04245	COG3401	FG-GAP repeat protein
ETL58_RS04250	COG2755	lipolytic protein G-D-S-L family
ETL58_RS04255	COG1874	Beta-galactosidase
ETL58_RS04265	COG1653	transport
ETL58_RS04270	COG4209	transmembrane transport
ETL58_RS04275	COG0395	ABC-type sugar transport system, permease component
ETL58_RS04280	COG1486	melibiose metabolic process
ETL58_RS04285	COG2323	membrane
ETL58_RS04290	COG2329	Antibiotic biosynthesis monooxygenase
ETL58_RS04295	COG0346	lactoylglutathione lyase activity
ETL58_RS04310	COG5583	Uncharacterized small protein (DUF2292)
ETL58_RS04315	COG0670	Belongs to the BI1 family
ETL58_RS04320	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ETL58_RS04355	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ETL58_RS04355	COG2124	cytochrome p450
ETL58_RS04360	COG1368	sulfuric ester hydrolase activity
ETL58_RS04365	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ETL58_RS04370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ETL58_RS04375	COG1442	glycosyl transferase family 8
ETL58_RS04380	COG1216	Glycosyl transferase, family 2
ETL58_RS04385	COG1442	glycosyl transferase family 8
ETL58_RS04390	COG2223	nitrite transmembrane transporter activity
ETL58_RS04395	COG1011	Hydrolase
ETL58_RS04400	COG0531	amino acid
ETL58_RS04405	COG1012	belongs to the aldehyde dehydrogenase family
ETL58_RS04410	COG0840	transmembrane signaling receptor activity
ETL58_RS04415	COG0488	(ABC) transporter
ETL58_RS04425	COG0789	Transcriptional regulator
ETL58_RS04430	COG2814	Major facilitator Superfamily
ETL58_RS04445	COG0488	(ABC) transporter
ETL58_RS04450	COG0513	Belongs to the DEAD box helicase family
ETL58_RS04455	COG0456	acetyltransferase
ETL58_RS04460	COG2130	NADP-dependent
ETL58_RS04470	COG2211	Major facilitator Superfamily
ETL58_RS04475	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ETL58_RS04480	COG1120	ATPase activity
ETL58_RS04485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETL58_RS04490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETL58_RS04495	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
ETL58_RS04510	COG3866	Pectate lyase
ETL58_RS04515	COG0471	metal ion transport
ETL58_RS04520	COG3290	protein histidine kinase activity
ETL58_RS04525	COG4565	transcriptional regulatory protein
ETL58_RS04530	COG3181	Tripartite tricarboxylate transporter family receptor
ETL58_RS04535	COG2851	Citrate transporter
ETL58_RS04540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETL58_RS04545	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
ETL58_RS04550	COG1254	Belongs to the acylphosphatase family
ETL58_RS04555	COG2258	MOSC domain
ETL58_RS04575	COG0024	Methionine aminopeptidase
ETL58_RS04580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETL58_RS04580	COG1263	PTS System
ETL58_RS04585	COG1368	sulfuric ester hydrolase activity
ETL58_RS04600	COG1115	amino acid carrier protein
ETL58_RS04605	COG0531	amino acid
ETL58_RS04620	COG0697	spore germination
ETL58_RS04625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETL58_RS04625	COG1263	PTS System
ETL58_RS04630	COG0366	Alpha amylase catalytic
ETL58_RS04635	COG2188	Transcriptional regulator
ETL58_RS04640	COG0778	Nitroreductase
ETL58_RS04645	COG0737	Belongs to the 5'-nucleotidase family
ETL58_RS04650	COG0693	protein deglycase activity
ETL58_RS04655	COG2814	Major facilitator Superfamily
ETL58_RS04660	COG4840	Belongs to the UPF0435 family
ETL58_RS04665	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ETL58_RS04670	COG4980	gas vesicle protein
ETL58_RS04675	COG1295	ribonuclease BN
ETL58_RS04680	COG0477	Major facilitator Superfamily
ETL58_RS04685	COG0387	Pfam Sodium calcium exchanger
ETL58_RS04695	COG0668	transmembrane transport
ETL58_RS04700	COG0535	radical SAM domain protein
ETL58_RS04710	COG0726	polysaccharide deacetylase
ETL58_RS04715	COG2084	Dehydrogenase
ETL58_RS04720	COG0598	Magnesium transport protein CorA
ETL58_RS04725	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ETL58_RS04730	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ETL58_RS04740	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ETL58_RS04745	COG4637	Psort location Cytoplasmic, score
ETL58_RS04755	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ETL58_RS04760	COG0022	dehydrogenase e1 component
ETL58_RS04765	COG0508	dehydrogenase complex catalyzes the overall conversion of
ETL58_RS04770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ETL58_RS04775	COG3284	Transcriptional regulator
ETL58_RS04785	COG1742	UPF0060 membrane protein
ETL58_RS04810	COG4842	Belongs to the WXG100 family
ETL58_RS04815	COG1486	melibiose metabolic process
ETL58_RS04820	COG1737	Transcriptional regulator
ETL58_RS04825	COG1263	PTS System
ETL58_RS04825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETL58_RS04830	COG1132	(ABC) transporter
ETL58_RS04835	COG1132	(ABC) transporter
ETL58_RS04840	COG2259	Doxx family
ETL58_RS04845	COG2514	catechol 2,3-dioxygenase activity
ETL58_RS04850	COG4585	Histidine kinase
ETL58_RS04855	COG2197	response regulator
ETL58_RS04860	COG1131	(ABC) transporter
ETL58_RS04865	COG1511	domain protein
ETL58_RS04865	COG0842	Transport permease protein
ETL58_RS04870	COG0842	Transport permease protein
ETL58_RS04875	COG1695	Transcriptional regulator
ETL58_RS04880	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
ETL58_RS04885	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
ETL58_RS04890	COG2318	DinB family
ETL58_RS04895	COG2814	Major facilitator Superfamily
ETL58_RS04900	COG1846	Transcriptional regulator
ETL58_RS04905	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ETL58_RS04905	COG0392	lysyltransferase activity
ETL58_RS04910	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ETL58_RS04915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETL58_RS04920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETL58_RS04925	COG0384	phenazine biosynthesis protein PhzF
ETL58_RS04930	COG0778	Nitroreductase
ETL58_RS04945	COG1090	epimerase
ETL58_RS04950	COG2137	regulation of response to DNA damage stimulus
ETL58_RS04960	COG2814	Major facilitator Superfamily
ETL58_RS04975	COG3103	Sh3 type 3 domain protein
ETL58_RS04980	COG5658	integral membrane protein
ETL58_RS04985	COG0596	Alpha beta hydrolase
ETL58_RS04990	COG0463	Glycosyl transferase, family 2
ETL58_RS04995	COG4485	Bacterial membrane protein, YfhO
ETL58_RS05000	COG1988	membrane-bound metal-dependent
ETL58_RS05005	COG1194	a g-specific adenine glycosylase
ETL58_RS05015	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_RS05030	COG3557	Belongs to the UPF0374 family
ETL58_RS05035	COG1132	(ABC) transporter
ETL58_RS05040	COG4129	membrane
ETL58_RS05045	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ETL58_RS05050	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ETL58_RS05055	COG0735	belongs to the Fur family
ETL58_RS05165	COG4326	sporulation control protein
ETL58_RS05175	COG5577	PFAM Coat F domain
ETL58_RS05180	COG3340	Belongs to the peptidase S51 family
ETL58_RS05185	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ETL58_RS05190	COG0277	FAD linked oxidase domain protein
ETL58_RS05200	COG0753	catalase activity
ETL58_RS05205	COG1116	anion transmembrane transporter activity
ETL58_RS05210	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ETL58_RS05215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ETL58_RS05220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ETL58_RS05230	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ETL58_RS05240	COG1476	TRANSCRIPTIONal
ETL58_RS05250	COG3382	B3 4 domain protein
ETL58_RS05255	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ETL58_RS05265	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ETL58_RS05270	COG0789	Transcriptional regulator
ETL58_RS05275	COG1664	Polymer-forming cytoskeletal
ETL58_RS05280	COG1664	Polymer-forming cytoskeletal
ETL58_RS05285	COG2766	serine protein kinase
ETL58_RS05290	COG2718	Belongs to the UPF0229 family
ETL58_RS05295	COG1846	Transcriptional regulator
ETL58_RS05300	COG1566	PFAM secretion protein HlyD family protein
ETL58_RS05305	COG2814	Major facilitator Superfamily
ETL58_RS05310	COG0655	NAD(P)H dehydrogenase (quinone) activity
ETL58_RS05330	COG1725	Transcriptional regulator
ETL58_RS05335	COG1131	(ABC) transporter
ETL58_RS05340	COG1131	(ABC) transporter
ETL58_RS05345	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
ETL58_RS05350	COG1278	Cold shock
ETL58_RS05360	COG1464	Belongs to the NlpA lipoprotein family
ETL58_RS05365	COG3706	GGDEF domain
ETL58_RS05370	COG1823	symporter activity
ETL58_RS05390	COG5577	PFAM Coat F domain
ETL58_RS05395	COG0737	Belongs to the 5'-nucleotidase family
ETL58_RS05395	COG1525	nuclease
ETL58_RS05395	COG4085	toxin activity
ETL58_RS05400	COG3764	Sortase (surface protein transpeptidase)
ETL58_RS05405	COG0564	pseudouridine synthase activity
ETL58_RS05415	COG0517	IMP dehydrogenase activity
ETL58_RS05420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ETL58_RS05425	COG3153	acetyltransferase
ETL58_RS05425	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ETL58_RS05430	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ETL58_RS05435	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
ETL58_RS05440	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ETL58_RS05445	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ETL58_RS05450	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ETL58_RS05455	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ETL58_RS05460	COG2203	Gaf domain
ETL58_RS05460	COG4585	Histidine kinase
ETL58_RS05465	COG2197	response regulator
ETL58_RS05470	COG0431	NADPH-dependent FMN reductase
ETL58_RS05485	COG0791	NLP P60 protein
ETL58_RS05485	COG1388	LysM domain
ETL58_RS05490	COG1959	2 iron, 2 sulfur cluster binding
ETL58_RS05495	COG0668	transmembrane transport
ETL58_RS05500	COG2719	SpoVR family
ETL58_RS05505	COG1785	Belongs to the alkaline phosphatase family
ETL58_RS05510	COG0791	NLP P60 protein
ETL58_RS05510	COG1388	LysM domain
ETL58_RS05515	COG0583	DNA-binding transcription factor activity
ETL58_RS05520	COG0372	Belongs to the citrate synthase family
ETL58_RS05525	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_RS05530	COG0531	amino acid
ETL58_RS05535	COG0733	neurotransmitter:sodium symporter activity
ETL58_RS05540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ETL58_RS05545	COG0456	acetyltransferase
ETL58_RS05560	COG1595	DNA-templated transcription, initiation
ETL58_RS05565	COG0667	Aldo Keto reductase
ETL58_RS05570	COG0204	Acyl-transferase
ETL58_RS05575	COG1253	flavin adenine dinucleotide binding
ETL58_RS05580	COG0789	Transcriptional regulator
ETL58_RS05585	COG0436	Aminotransferase
ETL58_RS05590	COG1253	flavin adenine dinucleotide binding
ETL58_RS05595	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ETL58_RS05600	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ETL58_RS05605	COG0584	glycerophosphoryl diester phosphodiesterase
ETL58_RS05615	COG0668	transmembrane transport
ETL58_RS05620	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ETL58_RS05625	COG0726	polysaccharide deacetylase
ETL58_RS05630	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ETL58_RS05635	COG1757	Na H antiporter
ETL58_RS05640	COG0589	response to stress
ETL58_RS05650	COG1132	(ABC) transporter
ETL58_RS05655	COG1132	(ABC) transporter
ETL58_RS05660	COG0702	epimerase
ETL58_RS05680	COG0189	ligase activity
ETL58_RS05685	COG0189	ligase activity
ETL58_RS05690	COG4399	Belongs to the UPF0754 family
ETL58_RS05695	COG3679	Belongs to the UPF0342 family
ETL58_RS05700	COG4335	DNA alkylation repair
ETL58_RS05705	COG0561	phosphatase activity
ETL58_RS05710	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ETL58_RS05715	COG0475	glutathione-regulated potassium exporter activity
ETL58_RS05720	COG0490	domain, Protein
ETL58_RS05730	COG1024	Enoyl-CoA hydratase
ETL58_RS05740	COG4152	abc transporter atp-binding protein
ETL58_RS05745	COG1668	transmembrane transport
ETL58_RS05750	COG0420	3'-5' exonuclease activity
ETL58_RS05755	COG4717	serine-type aminopeptidase activity
ETL58_RS05760	COG3481	metal-dependent phosphohydrolase, HD sub domain
ETL58_RS05770	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ETL58_RS05800	COG1846	Transcriptional regulator
ETL58_RS05805	COG4980	gas vesicle protein
ETL58_RS05820	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ETL58_RS05825	COG0537	adenosine 5'-monophosphoramidase activity
ETL58_RS05830	COG1131	(ABC) transporter
ETL58_RS05835	COG4473	ABC transporter
ETL58_RS05845	COG1473	amidohydrolase
ETL58_RS05850	COG3069	C4-dicarboxylate transmembrane transporter activity
ETL58_RS05860	COG2329	Antibiotic biosynthesis monooxygenase
ETL58_RS05865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ETL58_RS05870	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ETL58_RS05875	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ETL58_RS05880	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
ETL58_RS05885	COG1309	transcriptional regulator
ETL58_RS05890	COG1511	domain protein
ETL58_RS05895	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ETL58_RS05900	COG4377	Putative membrane peptidase family (DUF2324)
ETL58_RS05910	COG1363	Peptidase, m42
ETL58_RS05915	COG4405	Protein conserved in bacteria
ETL58_RS05920	COG1301	dicarboxylic acid transport
ETL58_RS05930	COG1234	tRNA 3'-trailer cleavage
ETL58_RS05935	COG0095	Lipoate-protein ligase
ETL58_RS05940	COG0702	epimerase
ETL58_RS05945	COG0318	PFAM AMP-dependent synthetase and ligase
ETL58_RS05955	COG0501	Belongs to the peptidase M48B family
ETL58_RS05965	COG0456	acetyltransferase
ETL58_RS05970	COG0604	alcohol dehydrogenase
ETL58_RS05975	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
ETL58_RS05980	COG0406	alpha-ribazole phosphatase activity
ETL58_RS05985	COG0183	Belongs to the thiolase family
ETL58_RS05990	COG0318	PFAM AMP-dependent synthetase and ligase
ETL58_RS05995	COG1268	BioY protein
ETL58_RS06000	COG0840	transmembrane signaling receptor activity
ETL58_RS06005	COG0723	plastoquinol--plastocyanin reductase activity
ETL58_RS06005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ETL58_RS06010	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_RS06020	COG4903	ComK protein
ETL58_RS06025	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_RS06035	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ETL58_RS06050	COG0398	Pfam SNARE associated Golgi protein
ETL58_RS06055	COG0681	Belongs to the peptidase S26 family
ETL58_RS06060	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ETL58_RS06065	COG1846	Transcriptional regulator
ETL58_RS06070	COG0738	Major facilitator superfamily
ETL58_RS06075	COG0673	inositol 2-dehydrogenase activity
ETL58_RS06080	COG0561	phosphatase activity
ETL58_RS06085	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ETL58_RS06090	COG1609	Transcriptional regulator
ETL58_RS06095	COG3180	Ammonia monooxygenase
ETL58_RS06100	COG0477	Major facilitator Superfamily
ETL58_RS06100	COG2814	Major facilitator Superfamily
ETL58_RS06105	COG4533	DNA binding
ETL58_RS06115	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
ETL58_RS06120	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
ETL58_RS06125	COG1074	ATP-dependent DNA helicase activity
ETL58_RS06130	COG0420	3'-5' exonuclease activity
ETL58_RS06135	COG0419	ATPase involved in DNA repair
ETL58_RS06140	COG1403	HNH endonuclease
ETL58_RS06180	COG5337	Spore coat protein CotH
ETL58_RS06185	COG0179	Fumarylacetoacetate (FAA) hydrolase
ETL58_RS06195	COG1404	Belongs to the peptidase S8 family
ETL58_RS06205	COG0367	asparagine synthase
ETL58_RS06210	COG2318	DinB family
ETL58_RS06215	COG1562	ergosterol biosynthetic process
ETL58_RS06220	COG0534	Mate efflux family protein
ETL58_RS06225	COG1917	Cupin 2, conserved barrel domain protein
ETL58_RS06225	COG2207	Transcriptional regulator
ETL58_RS06230	COG1609	Transcriptional regulator
ETL58_RS06235	COG0673	inositol 2-dehydrogenase activity
ETL58_RS06240	COG2318	DinB family
ETL58_RS06245	COG1279	arginine transmembrane transporter activity
ETL58_RS06250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ETL58_RS06255	COG1357	PFAM Pentapeptide repeats (8 copies)
ETL58_RS06260	COG2267	carboxylic ester hydrolase activity
ETL58_RS06265	COG0529	Catalyzes the synthesis of activated sulfate
ETL58_RS06270	COG2046	Belongs to the sulfate adenylyltransferase family
ETL58_RS06275	COG0175	sulfate reduction
ETL58_RS06280	COG2045	Belongs to the ComB family
ETL58_RS06285	COG1809	phosphosulfolactate synthase activity
ETL58_RS06290	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETL58_RS06295	COG4948	Mandelate Racemase Muconate Lactonizing
ETL58_RS06300	COG2814	Major facilitator Superfamily
ETL58_RS06305	COG0454	-acetyltransferase
ETL58_RS06310	COG2153	protein acetylation
ETL58_RS06315	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ETL58_RS06315	COG0646	methionine synthase
ETL58_RS06320	COG1666	GTP binding
ETL58_RS06325	COG2996	Protein conserved in bacteria
ETL58_RS06345	COG1695	Transcriptional regulator
ETL58_RS06360	COG3227	Zinc metalloprotease (Elastase)
ETL58_RS06365	COG1307	EDD domain protein, DegV family
ETL58_RS06370	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETL58_RS06385	COG0561	phosphatase activity
ETL58_RS06390	COG1073	alpha beta
ETL58_RS06395	COG2151	metal-sulfur cluster biosynthetic enzyme
ETL58_RS06405	COG0277	FAD linked oxidase domain protein
ETL58_RS06410	COG2271	Major facilitator Superfamily
ETL58_RS06415	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ETL58_RS06420	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ETL58_RS06430	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ETL58_RS06435	COG0505	Belongs to the CarA family
ETL58_RS06440	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ETL58_RS06445	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ETL58_RS06460	COG2267	carboxylic ester hydrolase activity
ETL58_RS06470	COG1744	ABC transporter substrate-binding protein PnrA-like
ETL58_RS06485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ETL58_RS06490	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ETL58_RS06495	COG5504	Zn-dependent protease
ETL58_RS06500	COG0444	Belongs to the ABC transporter superfamily
ETL58_RS06505	COG4608	Belongs to the ABC transporter superfamily
ETL58_RS06515	COG0601	transmembrane transport
ETL58_RS06520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ETL58_RS06530	COG0180	Tryptophanyl-tRNA synthetase
ETL58_RS06535	COG4166	transmembrane transport
ETL58_RS06540	COG0601	transmembrane transport
ETL58_RS06545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ETL58_RS06550	COG0444	Belongs to the ABC transporter superfamily
ETL58_RS06555	COG4608	Belongs to the ABC transporter superfamily
ETL58_RS06560	COG2814	Major facilitator Superfamily
ETL58_RS06565	COG0456	acetyltransferase
ETL58_RS06570	COG1393	Belongs to the ArsC family
ETL58_RS06575	COG0861	Integral membrane protein TerC family
ETL58_RS06585	COG4862	establishment of competence for transformation
ETL58_RS06595	COG4469	Competence protein
ETL58_RS06600	COG1164	Oligoendopeptidase f
ETL58_RS06615	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ETL58_RS06620	COG2346	COG2346, Truncated hemoglobins
ETL58_RS06625	COG0741	lytic transglycosylase activity
ETL58_RS06630	COG4116	CYTH
ETL58_RS06640	COG2357	RelA SpoT domain protein
ETL58_RS06645	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ETL58_RS06650	COG0564	pseudouridine synthase activity
ETL58_RS06655	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ETL58_RS06660	COG0475	glutathione-regulated potassium exporter activity
ETL58_RS06660	COG0569	domain protein
ETL58_RS06665	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ETL58_RS06670	COG0352	thiamine-phosphate diphosphorylase activity
ETL58_RS06675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ETL58_RS06680	COG2104	thiamine diphosphate biosynthetic process
ETL58_RS06685	COG2022	thiamine diphosphate biosynthetic process
ETL58_RS06690	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ETL58_RS06695	COG0351	phosphomethylpyrimidine kinase
ETL58_RS06700	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ETL58_RS06755	COG0210	DNA helicase
ETL58_RS06765	COG2153	protein acetylation
ETL58_RS06770	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ETL58_RS06775	COG2382	esterase
ETL58_RS06780	COG0626	cystathionine gamma-synthase activity
ETL58_RS06785	COG0626	cystathionine gamma-synthase activity
ETL58_RS06790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ETL58_RS06795	COG5505	Protein of unknown function (DUF819)
ETL58_RS06830	COG5444	nuclease activity
ETL58_RS06855	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ETL58_RS06860	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_RS06870	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETL58_RS06870	COG3711	transcriptional antiterminator
ETL58_RS06875	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ETL58_RS06875	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ETL58_RS06875	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETL58_RS06880	COG1482	cell wall glycoprotein biosynthetic process
ETL58_RS06890	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ETL58_RS06900	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ETL58_RS06920	COG0109	protoheme IX farnesyltransferase activity
ETL58_RS06930	COG0726	polysaccharide deacetylase
ETL58_RS06945	COG5504	Zn-dependent protease
ETL58_RS06950	COG2205	protein histidine kinase activity
ETL58_RS06960	COG3383	formate dehydrogenase (NAD+) activity
ETL58_RS06965	COG2427	Protein of unknown function (DUF1641)
ETL58_RS06975	COG1051	belongs to the nudix hydrolase family
ETL58_RS06985	COG2124	cytochrome p450
ETL58_RS06990	COG1819	glycosyl
ETL58_RS07000	COG1587	Uroporphyrinogen-III synthase
ETL58_RS07005	COG0390	transport system, permease component
ETL58_RS07010	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ETL58_RS07015	COG0697	spore germination
ETL58_RS07020	COG4297	protein containing double-stranded beta helix domain
ETL58_RS07030	COG1252	NADH dehydrogenase
ETL58_RS07035	COG1904	glucuronate isomerase
ETL58_RS07040	COG2211	Major facilitator Superfamily
ETL58_RS07045	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ETL58_RS07050	COG1063	alcohol dehydrogenase
ETL58_RS07055	COG1312	Catalyzes the dehydration of D-mannonate
ETL58_RS07060	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_RS07065	COG2271	Major facilitator Superfamily
ETL58_RS07070	COG1609	Transcriptional regulator
ETL58_RS07075	COG0246	Mannitol dehydrogenase
ETL58_RS07080	COG2721	sulfolactate sulfo-lyase activity
ETL58_RS07085	COG0730	response to heat
ETL58_RS07090	COG2318	DinB family
ETL58_RS07095	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ETL58_RS07100	COG0457	Tetratricopeptide repeat
ETL58_RS07110	COG2350	Protein conserved in bacteria
ETL58_RS07115	COG5632	N-Acetylmuramoyl-L-alanine amidase
ETL58_RS07115	COG3409	Peptidoglycan-binding domain 1 protein
ETL58_RS07115	COG1388	LysM domain
ETL58_RS07125	COG4195	phage-related replication protein
ETL58_RS07130	COG3546	catalase activity
ETL58_RS07135	COG2856	Zn peptidase
ETL58_RS07140	COG1396	sequence-specific DNA binding
ETL58_RS07150	COG1522	sequence-specific DNA binding
ETL58_RS07155	COG1484	DNA-dependent DNA replication
ETL58_RS07175	COG1595	DNA-templated transcription, initiation
ETL58_RS07180	COG3728	DNA packaging
ETL58_RS07180	COG5484	DNA packaging
ETL58_RS07185	COG1783	phage Terminase large subunit
ETL58_RS07190	COG5518	Phage portal protein
ETL58_RS07195	COG0338	D12 class N6 adenine-specific DNA methyltransferase
ETL58_RS07200	COG4653	Phage capsid family
ETL58_RS07250	COG5412	phage tail tape measure protein
ETL58_RS07250	COG3953	SLT domain
ETL58_RS07255	COG1652	LysM domain
ETL58_RS07260	COG4193	domain, Protein
ETL58_RS07270	COG3628	GPW Gp25 family protein
ETL58_RS07275	COG3299	homolog of phage Mu protein gp47
ETL58_RS07280	COG3778	Protein conserved in bacteria
ETL58_RS07320	COG3409	Peptidoglycan-binding domain 1 protein
ETL58_RS07320	COG5632	N-Acetylmuramoyl-L-alanine amidase
ETL58_RS07340	COG0306	phosphate transporter
ETL58_RS07345	COG1392	Phosphate transport regulator
ETL58_RS07350	COG0531	amino acid
ETL58_RS07355	COG0346	lactoylglutathione lyase activity
ETL58_RS07360	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ETL58_RS07365	COG0463	Glycosyl transferase, family 2
ETL58_RS07370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETL58_RS07375	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ETL58_RS07380	COG2362	D-Aminopeptidase
ETL58_RS07385	COG0601	transmembrane transport
ETL58_RS07390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ETL58_RS07395	COG0444	Belongs to the ABC transporter superfamily
ETL58_RS07400	COG4166	transmembrane transport
ETL58_RS07405	COG1619	proteins homologs of microcin C7 resistance protein MccF
ETL58_RS07410	COG4948	Mandelate Racemase Muconate Lactonizing
ETL58_RS07415	COG0791	NLP P60 protein
ETL58_RS07420	COG4608	Belongs to the ABC transporter superfamily
ETL58_RS07425	COG2706	6-phosphogluconolactonase activity
ETL58_RS07430	COG1834	amidinotransferase
ETL58_RS07435	COG1607	acyl-coa hydrolase
ETL58_RS07440	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ETL58_RS07440	COG1017	nitric oxide dioxygenase activity
ETL58_RS07450	COG2323	membrane
ETL58_RS07455	COG2318	DinB family
ETL58_RS07460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ETL58_RS07465	COG2076	Multidrug Resistance protein
ETL58_RS07470	COG2076	Multidrug Resistance protein
ETL58_RS07475	COG0788	formyltetrahydrofolate deformylase activity
ETL58_RS07480	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ETL58_RS07485	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ETL58_RS07490	COG1764	response to oxidative stress
ETL58_RS07495	COG1846	Transcriptional regulator
ETL58_RS07500	COG1764	response to oxidative stress
ETL58_RS07510	COG0590	tRNA wobble adenosine to inosine editing
ETL58_RS07515	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ETL58_RS07520	COG1404	Belongs to the peptidase S8 family
ETL58_RS07525	COG1366	Belongs to the anti-sigma-factor antagonist family
ETL58_RS07530	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ETL58_RS07535	COG1122	ATPase activity
ETL58_RS07540	COG4721	ABC-type cobalt transport system, permease component
ETL58_RS07550	COG0745	RESPONSE REGULATOR receiver
ETL58_RS07555	COG3850	Histidine kinase
ETL58_RS07555	COG5002	protein histidine kinase activity
ETL58_RS07560	COG3212	peptidase
ETL58_RS07565	COG3212	peptidase
ETL58_RS07575	COG2239	Acts as a magnesium transporter
ETL58_RS07580	COG0789	Transcriptional regulator
ETL58_RS07595	COG1846	Transcriptional regulator
ETL58_RS07600	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ETL58_RS07605	COG0726	polysaccharide deacetylase
ETL58_RS07610	COG1408	metallophosphoesterase
ETL58_RS07620	COG0463	Glycosyl transferase, family 2
ETL58_RS07625	COG1793	dna ligase
ETL58_RS07625	COG3285	dna ligase
ETL58_RS07630	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
ETL58_RS07635	COG3300	MHYT domain
ETL58_RS07635	COG5001	Diguanylate cyclase
ETL58_RS07640	COG0586	Pfam SNARE associated Golgi protein
ETL58_RS07645	COG0861	Integral membrane protein TerC family
ETL58_RS07650	COG1191	sigma factor activity
ETL58_RS07670	COG0501	Belongs to the peptidase M48B family
ETL58_RS07675	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ETL58_RS07690	COG3594	Acyltransferase
ETL58_RS07695	COG5002	protein histidine kinase activity
ETL58_RS07700	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ETL58_RS07710	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ETL58_RS07715	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
ETL58_RS07720	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ETL58_RS07725	COG0436	Aminotransferase
ETL58_RS07730	COG1850	ribulose-bisphosphate carboxylase activity
ETL58_RS07735	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
ETL58_RS07740	COG0235	Class ii aldolase
ETL58_RS07745	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
ETL58_RS07750	COG3339	Conserved Protein
ETL58_RS07765	COG3852	Histidine kinase
ETL58_RS07770	COG1846	Transcriptional regulator
ETL58_RS07775	COG1360	Flagellar Motor Protein
ETL58_RS07780	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ETL58_RS07790	COG0542	response to heat
ETL58_RS07795	COG3949	Membrane
ETL58_RS07800	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ETL58_RS07805	COG0720	synthase
ETL58_RS07810	COG0602	queuosine metabolic process
ETL58_RS07815	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ETL58_RS07820	COG1733	regulation of RNA biosynthetic process
ETL58_RS07825	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_RS07835	COG1388	LysM domain
ETL58_RS07840	COG3858	chitin binding
ETL58_RS07850	COG4873	Protein conserved in bacteria
ETL58_RS07860	COG3773	Cell wall hydrolase
ETL58_RS07865	COG2244	polysaccharide biosynthetic process
ETL58_RS07870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETL58_RS07875	COG2217	Heavy metal translocating P-type atpase
ETL58_RS07885	COG0006	proline dipeptidase activity
ETL58_RS07890	COG1609	Transcriptional regulator
ETL58_RS07895	COG3711	transcriptional antiterminator
ETL58_RS07900	COG1263	PTS System
ETL58_RS07900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETL58_RS07900	COG2190	(PTS) system
ETL58_RS07905	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETL58_RS07910	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ETL58_RS07920	COG1533	DNA photolyase activity
ETL58_RS07925	COG0456	acetyltransferase
ETL58_RS07930	COG0840	transmembrane signaling receptor activity
ETL58_RS07935	COG2084	Dehydrogenase
ETL58_RS07940	COG2340	Cysteine-rich secretory protein family
ETL58_RS07945	COG0768	penicillin binding
ETL58_RS07950	COG4191	Histidine kinase
ETL58_RS07955	COG0436	Aminotransferase
ETL58_RS07965	COG0784	Response regulator, receiver
ETL58_RS07965	COG0835	chemotaxis
ETL58_RS07975	COG2814	Major facilitator Superfamily
ETL58_RS07980	COG1376	ErfK ybiS ycfS ynhG family protein
ETL58_RS07985	COG1408	metallophosphoesterase
ETL58_RS07990	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_RS07995	COG2200	EAL domain
ETL58_RS08000	COG4703	Protein of unknown function (DUF1797)
ETL58_RS08005	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
ETL58_RS08015	COG0517	IMP dehydrogenase activity
ETL58_RS08020	COG0583	DNA-binding transcription factor activity
ETL58_RS08025	COG0716	FMN binding
ETL58_RS08035	COG0716	FMN binding
ETL58_RS08040	COG2171	N-acyltransferase activity
ETL58_RS08045	COG1473	amidohydrolase
ETL58_RS08055	COG0668	transmembrane transport
ETL58_RS08060	COG0450	alkyl hydroperoxide reductase
ETL58_RS08065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETL58_RS08080	COG0746	molybdenum cofactor guanylyltransferase activity
ETL58_RS08085	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ETL58_RS08090	COG0303	'Molybdopterin
ETL58_RS08095	COG1763	Mo-molybdopterin cofactor biosynthetic process
ETL58_RS08100	COG0314	molybdopterin synthase activity
ETL58_RS08105	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ETL58_RS08110	COG1132	(ABC) transporter
ETL58_RS08115	COG1132	(ABC) transporter
ETL58_RS08125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ETL58_RS08130	COG1136	(ABC) transporter
ETL58_RS08135	COG0577	efflux transmembrane transporter activity
ETL58_RS08140	COG1349	DNA-binding transcription factor activity
ETL58_RS08145	COG1105	Belongs to the carbohydrate kinase PfkB family
ETL58_RS08150	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ETL58_RS08150	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ETL58_RS08150	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETL58_RS08155	COG0681	Belongs to the peptidase S26 family
ETL58_RS08165	COG0488	(ABC) transporter
ETL58_RS08170	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ETL58_RS08175	COG2309	aminopeptidase activity
ETL58_RS08185	COG1077	Cell shape determining protein MreB Mrl
ETL58_RS08190	COG2002	toxin-antitoxin pair type II binding
ETL58_RS08195	COG3852	Histidine kinase
ETL58_RS08200	COG2105	PFAM AIG2 family protein
ETL58_RS08200	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
ETL58_RS08205	COG0569	domain protein
ETL58_RS08210	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ETL58_RS08215	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ETL58_RS08220	COG5503	Protein of unknown function (DUF1447)
ETL58_RS08225	COG0561	phosphatase activity
ETL58_RS08230	COG0242	peptide deformylase activity
ETL58_RS08240	COG0497	DNA recombination
ETL58_RS08245	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ETL58_RS08250	COG0022	dehydrogenase e1 component
ETL58_RS08255	COG0508	dehydrogenase complex catalyzes the overall conversion of
ETL58_RS08260	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ETL58_RS08265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETL58_RS08275	COG1982	Orn Lys Arg decarboxylase major
ETL58_RS08280	COG4476	Belongs to the UPF0223 family
ETL58_RS08285	COG4493	Belongs to the UPF0637 family
ETL58_RS08295	COG0483	inositol monophosphate 1-phosphatase activity
ETL58_RS08305	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
ETL58_RS08325	COG1595	DNA-templated transcription, initiation
ETL58_RS08345	COG1217	gtp-binding protein TYPA
ETL58_RS08355	COG4896	Protein conserved in bacteria
ETL58_RS08365	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ETL58_RS08370	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ETL58_RS08375	COG2066	Belongs to the glutaminase family
ETL58_RS08380	COG4838	Belongs to the UPF0358 family
ETL58_RS08385	COG0772	Belongs to the SEDS family
ETL58_RS08390	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ETL58_RS08395	COG1612	heme a metabolic process
ETL58_RS08400	COG0109	protoheme IX farnesyltransferase activity
ETL58_RS08405	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ETL58_RS08405	COG2010	Cytochrome c
ETL58_RS08410	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ETL58_RS08415	COG1845	cytochrome c oxidase, subunit III
ETL58_RS08420	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ETL58_RS08425	COG3336	cytochrome c oxidase
ETL58_RS08435	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
ETL58_RS08440	COG2340	Cysteine-rich secretory protein family
ETL58_RS08455	COG3679	Belongs to the UPF0342 family
ETL58_RS08460	COG4471	UPF0298 protein
ETL58_RS08465	COG0742	ribosomal rna small subunit methyltransferase
ETL58_RS08470	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ETL58_RS08475	COG3314	Sporulation integral membrane protein YlbJ
ETL58_RS08480	COG1752	Esterase of the alpha-beta hydrolase superfamily
ETL58_RS08485	COG3480	Lon protease (S16) C-terminal proteolytic domain
ETL58_RS08490	COG1323	Belongs to the UPF0348 family
ETL58_RS08500	COG1399	metal-binding, possibly nucleic acid-binding protein
ETL58_RS08515	COG0454	-acetyltransferase
ETL58_RS08520	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ETL58_RS08525	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
ETL58_RS08530	COG2001	Belongs to the MraZ family
ETL58_RS08535	COG0275	rRNA processing
ETL58_RS08540	COG4839	cell division protein FtsL
ETL58_RS08545	COG0768	penicillin binding
ETL58_RS08550	COG0768	penicillin binding
ETL58_RS08555	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ETL58_RS08560	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ETL58_RS08565	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ETL58_RS08570	COG0772	Belongs to the SEDS family
ETL58_RS08575	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ETL58_RS08580	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ETL58_RS08585	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ETL58_RS08590	COG3879	Bacterial protein of unknown function (DUF881)
ETL58_RS08595	COG3879	Bacterial protein of unknown function (DUF881)
ETL58_RS08600	COG3856	small basic protein
ETL58_RS08605	COG0849	cell division
ETL58_RS08610	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ETL58_RS08615	COG4412	M6 family metalloprotease domain protein
ETL58_RS08615	COG1404	Belongs to the peptidase S8 family
ETL58_RS08625	COG1191	sigma factor activity
ETL58_RS08630	COG1191	sigma factor activity
ETL58_RS08635	COG1119	ATPase activity
ETL58_RS08640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ETL58_RS08645	COG1873	PFAM PRC-barrel domain
ETL58_RS08650	COG1496	oxidoreductase activity
ETL58_RS08655	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ETL58_RS08660	COG1799	cell septum assembly
ETL58_RS08665	COG0762	integral membrane protein
ETL58_RS08670	COG2302	S4 RNA-binding domain
ETL58_RS08675	COG3599	regulation of cell shape
ETL58_RS08680	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ETL58_RS08685	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ETL58_RS08690	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ETL58_RS08695	COG0564	pseudouridine synthase activity
ETL58_RS08700	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ETL58_RS08705	COG2233	PERMEase
ETL58_RS08710	COG0540	Belongs to the ATCase OTCase family
ETL58_RS08715	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ETL58_RS08720	COG0505	Belongs to the CarA family
ETL58_RS08725	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ETL58_RS08730	COG0543	2 iron, 2 sulfur cluster binding
ETL58_RS08735	COG0167	dihydroorotate dehydrogenase activity
ETL58_RS08740	COG0284	orotidine-5'-phosphate decarboxylase activity
ETL58_RS08745	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ETL58_RS08750	COG0175	sulfate reduction
ETL58_RS08755	COG0306	phosphate transporter
ETL58_RS08760	COG2046	Belongs to the sulfate adenylyltransferase family
ETL58_RS08765	COG0529	Catalyzes the synthesis of activated sulfate
ETL58_RS08770	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ETL58_RS08775	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
ETL58_RS08780	COG1648	precorrin-2 dehydrogenase activity
ETL58_RS08785	COG1293	RNA-binding protein homologous to eukaryotic snRNP
ETL58_RS08790	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ETL58_RS08795	COG1561	YicC-like family, N-terminal region
ETL58_RS08805	COG0194	GDP metabolic process
ETL58_RS08810	COG1758	RNA polymerase activity
ETL58_RS08815	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ETL58_RS08820	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ETL58_RS08825	COG0242	peptide deformylase activity
ETL58_RS08830	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ETL58_RS08835	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ETL58_RS08835	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ETL58_RS08840	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ETL58_RS08845	COG0631	protein serine/threonine phosphatase activity
ETL58_RS08850	COG0515	serine threonine protein kinase
ETL58_RS08850	COG2815	serine threonine protein kinase
ETL58_RS08855	COG1162	GTPase activity
ETL58_RS08860	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ETL58_RS08865	COG1564	THIamine pyrophosphokinase
ETL58_RS08875	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ETL58_RS08880	COG1302	Protein conserved in bacteria
ETL58_RS08885	COG1461	Dihydroxyacetone kinase
ETL58_RS08890	COG1760	l-serine dehydratase
ETL58_RS08895	COG1760	l-serine dehydratase
ETL58_RS08900	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ETL58_RS08905	COG2050	protein possibly involved in aromatic compounds catabolism
ETL58_RS08905	COG1349	DNA-binding transcription factor activity
ETL58_RS08910	COG0416	fatty acid biosynthetic process
ETL58_RS08915	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ETL58_RS08920	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_RS08930	COG0571	ribonuclease III activity
ETL58_RS08935	COG1196	nuclear chromosome segregation
ETL58_RS08940	COG0552	protein localization to endoplasmic reticulum
ETL58_RS08950	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
ETL58_RS08955	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ETL58_RS08960	COG0228	four-way junction DNA binding
ETL58_RS08965	COG1837	Belongs to the UPF0109 family
ETL58_RS08975	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ETL58_RS08980	COG0336	Belongs to the RNA methyltransferase TrmD family
ETL58_RS08985	COG0335	large ribosomal subunit rRNA binding
ETL58_RS08990	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ETL58_RS08995	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ETL58_RS09005	COG2257	FlhB HrpN YscU SpaS Family
ETL58_RS09010	COG0045	succinate-CoA ligase (ADP-forming) activity
ETL58_RS09015	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ETL58_RS09020	COG0758	DNA mediated transformation
ETL58_RS09025	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ETL58_RS09030	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
ETL58_RS09035	COG4974	Belongs to the 'phage' integrase family
ETL58_RS09040	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ETL58_RS09045	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ETL58_RS09050	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
ETL58_RS09055	COG1815	bacterial-type flagellum-dependent cell motility
ETL58_RS09060	COG1558	bacterial-type flagellum-dependent cell motility
ETL58_RS09065	COG1677	Flagellar hook-basal body complex protein FliE
ETL58_RS09070	COG1766	The M ring may be actively involved in energy transduction
ETL58_RS09075	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ETL58_RS09080	COG1317	bacterial-type flagellum organization
ETL58_RS09085	COG1157	protein secretion by the type III secretion system
ETL58_RS09090	COG2882	bacterial-type flagellum organization
ETL58_RS09095	COG3334	PFAM MgtE intracellular
ETL58_RS09100	COG3144	bacterial-type flagellum assembly
ETL58_RS09105	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ETL58_RS09110	COG4786	Flagellar basal body rod
ETL58_RS09115	COG1582	Flagellar protein (FlbD)
ETL58_RS09120	COG1580	Controls the rotational direction of flagella during chemotaxis
ETL58_RS09125	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ETL58_RS09130	COG1776	CheC inhibitor of MCP methylation
ETL58_RS09130	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ETL58_RS09135	COG2201	protein-glutamate methylesterase activity
ETL58_RS09140	COG3190	flagellar
ETL58_RS09145	COG1338	Plays a role in the flagellum-specific transport system
ETL58_RS09150	COG1987	bacterial-type flagellum assembly
ETL58_RS09155	COG1684	flagellar biosynthetic protein fliR
ETL58_RS09160	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ETL58_RS09165	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ETL58_RS09170	COG1419	protein localization to endoplasmic reticulum
ETL58_RS09175	COG0455	bacterial-type flagellum organization
ETL58_RS09180	COG2201	protein-glutamate methylesterase activity
ETL58_RS09185	COG0643	Histidine kinase
ETL58_RS09185	COG2198	Histidine kinase
ETL58_RS09190	COG0835	chemotaxis
ETL58_RS09195	COG1776	CheC inhibitor of MCP methylation
ETL58_RS09200	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ETL58_RS09205	COG1191	sigma factor activity
ETL58_RS09215	COG0052	Belongs to the universal ribosomal protein uS2 family
ETL58_RS09220	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ETL58_RS09225	COG0528	UMP kinase activity
ETL58_RS09230	COG0233	cytoplasmic translational termination
ETL58_RS09235	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ETL58_RS09240	COG4589	Belongs to the CDS family
ETL58_RS09245	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ETL58_RS09250	COG0750	zinc metalloprotease
ETL58_RS09255	COG0442	prolyl-tRNA aminoacylation
ETL58_RS09260	COG2176	DNA-directed DNA polymerase activity
ETL58_RS09265	COG0779	Required for maturation of 30S ribosomal subunits
ETL58_RS09270	COG0195	Participates in both transcription termination and antitermination
ETL58_RS09275	COG2740	Nucleic-acid-binding protein implicated in transcription termination
ETL58_RS09280	COG1358	cellular component organization or biogenesis
ETL58_RS09285	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ETL58_RS09290	COG1550	Protein conserved in bacteria
ETL58_RS09295	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ETL58_RS09300	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ETL58_RS09305	COG0196	riboflavin kinase activity
ETL58_RS09310	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ETL58_RS09315	COG1185	polyribonucleotide nucleotidyltransferase activity
ETL58_RS09320	COG0726	polysaccharide deacetylase
ETL58_RS09325	COG0612	Peptidase, M16
ETL58_RS09330	COG1873	PFAM PRC-barrel domain
ETL58_RS09335	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ETL58_RS09340	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ETL58_RS09345	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ETL58_RS09350	COG0527	aspartate kinase activity
ETL58_RS09355	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ETL58_RS09360	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ETL58_RS09365	COG0740	serine-type endopeptidase activity
ETL58_RS09375	COG4980	gas vesicle protein
ETL58_RS09375	COG1674	ftsk spoiiie
ETL58_RS09380	COG2188	Transcriptional regulator
ETL58_RS09385	COG2814	Major facilitator Superfamily
ETL58_RS09390	COG0612	Peptidase, M16
ETL58_RS09395	COG0612	Peptidase, M16
ETL58_RS09400	COG0300	oxidoreductase activity
ETL58_RS09415	COG1426	Protein conserved in bacteria
ETL58_RS09420	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ETL58_RS09425	COG1546	Belongs to the CinA family
ETL58_RS09425	COG1058	Belongs to the CinA family
ETL58_RS09430	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ETL58_RS09435	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ETL58_RS09440	COG1418	mRNA catabolic process
ETL58_RS09445	COG1692	metallophosphoesterase
ETL58_RS09450	COG2359	stage V sporulation protein S
ETL58_RS09455	COG1063	alcohol dehydrogenase
ETL58_RS09460	COG0156	8-amino-7-oxononanoate synthase activity
ETL58_RS09465	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ETL58_RS09470	COG4550	Control of competence regulator ComK, YlbF/YmcA
ETL58_RS09480	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ETL58_RS09485	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ETL58_RS09500	COG3226	Transcriptional regulator
ETL58_RS09505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETL58_RS09515	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ETL58_RS09520	COG3321	synthase
ETL58_RS09525	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ETL58_RS09525	COG2070	2-Nitropropane dioxygenase
ETL58_RS09530	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETL58_RS09535	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ETL58_RS09540	COG3425	synthase
ETL58_RS09545	COG1024	Enoyl-CoA hydratase
ETL58_RS09550	COG1024	Enoyl-CoA hydratase
ETL58_RS09555	COG3321	synthase
ETL58_RS09555	COG0318	PFAM AMP-dependent synthetase and ligase
ETL58_RS09555	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETL58_RS09555	COG0300	oxidoreductase activity
ETL58_RS09555	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_RS09560	COG4221	oxidoreductase activity
ETL58_RS09560	COG3321	synthase
ETL58_RS09560	COG0300	oxidoreductase activity
ETL58_RS09560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETL58_RS09565	COG3321	synthase
ETL58_RS09565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ETL58_RS09565	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETL58_RS09565	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETL58_RS09565	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_RS09570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETL58_RS09570	COG3321	synthase
ETL58_RS09570	COG4221	oxidoreductase activity
ETL58_RS09570	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_RS09575	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ETL58_RS09575	COG3321	synthase
ETL58_RS09575	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
ETL58_RS09575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETL58_RS09580	COG2124	cytochrome p450
ETL58_RS09590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETL58_RS09595	COG1404	Belongs to the peptidase S8 family
ETL58_RS09605	COG4195	phage-related replication protein
ETL58_RS09610	COG1764	response to oxidative stress
ETL58_RS09615	COG2076	Multidrug Resistance protein
ETL58_RS09620	COG2076	Multidrug Resistance protein
ETL58_RS09635	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ETL58_RS09640	COG1923	regulation of RNA biosynthetic process
ETL58_RS09655	COG1780	Probably involved in ribonucleotide reductase function
ETL58_RS09660	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ETL58_RS09665	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ETL58_RS09670	COG4112	unkown
ETL58_RS09675	COG0860	N-Acetylmuramoyl-L-alanine amidase
ETL58_RS09685	COG0464	growth
ETL58_RS09690	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ETL58_RS09695	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
ETL58_RS09700	COG0789	Transcriptional regulator
ETL58_RS09705	COG0174	glutamine synthetase
ETL58_RS09725	COG4824	toxin secretion phage lysis holin
ETL58_RS09755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ETL58_RS09770	COG3655	Transcriptional regulator
ETL58_RS09785	COG0135	phosphoribosylanthranilate isomerase activity
ETL58_RS09790	COG2211	Major facilitator Superfamily
ETL58_RS09795	COG3507	Belongs to the glycosyl hydrolase 43 family
ETL58_RS09800	COG1940	carbohydrate kinase activity
ETL58_RS09805	COG2115	Belongs to the xylose isomerase family
ETL58_RS09810	COG1070	Carbohydrate kinase
ETL58_RS09820	COG1525	nuclease
ETL58_RS09825	COG2814	Major facilitator Superfamily
ETL58_RS09830	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ETL58_RS09840	COG0756	dUTP diphosphatase activity
ETL58_RS09880	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ETL58_RS09895	COG3832	glyoxalase III activity
ETL58_RS09910	COG0697	spore germination
ETL58_RS09915	COG0531	amino acid
ETL58_RS09945	COG4195	phage-related replication protein
ETL58_RS09955	COG0346	lactoylglutathione lyase activity
ETL58_RS09965	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ETL58_RS09970	COG1388	LysM domain
ETL58_RS09975	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ETL58_RS09980	COG4224	UPF0291 protein
ETL58_RS09985	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ETL58_RS09995	COG3763	UPF0154 protein
ETL58_RS10005	COG0785	Cytochrome C biogenesis protein
ETL58_RS10010	COG2201	protein-glutamate methylesterase activity
ETL58_RS10015	COG4846	Membrane protein involved in cytochrome C biogenesis
ETL58_RS10025	COG0071	Belongs to the small heat shock protein (HSP20) family
ETL58_RS10040	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ETL58_RS10045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETL58_RS10065	COG0824	Thioesterase
ETL58_RS10075	COG4841	protein insertion into membrane
ETL58_RS10080	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ETL58_RS10085	COG1832	CoA-binding protein
ETL58_RS10090	COG0187	DNA topoisomerase II activity
ETL58_RS10095	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ETL58_RS10105	COG1115	amino acid carrier protein
ETL58_RS10110	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ETL58_RS10120	COG5520	Belongs to the glycosyl hydrolase 30 family
ETL58_RS10125	COG3507	Belongs to the glycosyl hydrolase 43 family
ETL58_RS10135	COG2246	polysaccharide biosynthetic process
ETL58_RS10140	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ETL58_RS10145	COG0586	Pfam SNARE associated Golgi protein
ETL58_RS10150	COG2404	hydrolase activity, acting on ester bonds
ETL58_RS10155	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ETL58_RS10160	COG1024	Enoyl-CoA hydratase
ETL58_RS10165	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ETL58_RS10170	COG0511	ligase activity, forming carbon-carbon bonds
ETL58_RS10175	COG0439	Biotin carboxylase
ETL58_RS10180	COG0318	PFAM AMP-dependent synthetase and ligase
ETL58_RS10185	COG1960	acyl-CoA dehydrogenase activity
ETL58_RS10195	COG1649	PFAM Uncharacterised BCR, COG1649
ETL58_RS10205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETL58_RS10205	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
ETL58_RS10210	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETL58_RS10215	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETL58_RS10220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETL58_RS10225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETL58_RS10230	COG2027	D-alanyl-D-alanine carboxypeptidase
ETL58_RS10235	COG2017	converts alpha-aldose to the beta-anomer
ETL58_RS10240	COG0534	Mate efflux family protein
ETL58_RS10255	COG0582	viral genome integration into host DNA
ETL58_RS10260	COG0166	Belongs to the GPI family
ETL58_RS10265	COG0405	Gamma-glutamyltransferase
ETL58_RS10270	COG0583	DNA-binding transcription factor activity
ETL58_RS10275	COG0604	alcohol dehydrogenase
ETL58_RS10280	COG0493	'glutamate synthase
ETL58_RS10285	COG0067	glutamate synthase
ETL58_RS10285	COG0070	glutamate synthase
ETL58_RS10285	COG0069	glutamate synthase activity
ETL58_RS10290	COG0583	DNA-binding transcription factor activity
ETL58_RS10295	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ETL58_RS10300	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ETL58_RS10310	COG0300	oxidoreductase activity
ETL58_RS10315	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
ETL58_RS10325	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ETL58_RS10340	COG2814	Major facilitator Superfamily
ETL58_RS10345	COG1070	Carbohydrate kinase
ETL58_RS10350	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ETL58_RS10355	COG0243	molybdopterin cofactor binding
ETL58_RS10385	COG0840	transmembrane signaling receptor activity
ETL58_RS10385	COG5278	phosphoserine phosphatase activity
ETL58_RS10390	COG2368	4-hydroxyphenylacetate
ETL58_RS10395	COG4305	rare lipoprotein A
ETL58_RS10400	COG3619	membrane
ETL58_RS10405	COG3866	Pectate lyase
ETL58_RS10410	COG2135	peptidase activity
ETL58_RS10435	COG0456	acetyltransferase
ETL58_RS10455	COG2720	vancomycin resistance protein
ETL58_RS10465	COG3655	Transcriptional regulator
ETL58_RS10470	COG3739	integral membrane protein
ETL58_RS10475	COG0583	DNA-binding transcription factor activity
ETL58_RS10480	COG0697	spore germination
ETL58_RS10490	COG0693	protein deglycase activity
ETL58_RS10495	COG2367	Beta-lactamase
ETL58_RS10515	COG3848	Pyruvate phosphate dikinase
ETL58_RS10515	COG0574	Belongs to the PEP-utilizing enzyme family
ETL58_RS10520	COG0726	polysaccharide deacetylase
ETL58_RS10530	COG2314	TM2 domain
ETL58_RS10535	COG1396	sequence-specific DNA binding
ETL58_RS10580	COG2723	6-phospho-beta-galactosidase activity
ETL58_RS10595	COG0395	ABC-type sugar transport system, permease component
ETL58_RS10600	COG1175	transmembrane transport
ETL58_RS10610	COG1940	carbohydrate kinase activity
ETL58_RS10625	COG5444	nuclease activity
ETL58_RS10630	COG4282	regulation of fungal-type cell wall biogenesis
ETL58_RS10635	COG1231	oxidoreductase activity
ETL58_RS10640	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ETL58_RS10645	COG0662	Cupin 2, conserved barrel domain protein
ETL58_RS10645	COG2207	Transcriptional regulator
ETL58_RS10650	COG0456	acetyltransferase
ETL58_RS10655	COG1309	transcriptional regulator
ETL58_RS10660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETL58_RS10665	COG3708	Transcriptional regulator
ETL58_RS10670	COG2378	regulation of single-species biofilm formation
ETL58_RS10680	COG0640	Transcriptional regulator
ETL58_RS10685	COG0741	lytic transglycosylase activity
ETL58_RS10690	COG2322	membrane
ETL58_RS10705	COG1619	proteins homologs of microcin C7 resistance protein MccF
ETL58_RS10710	COG3239	Fatty acid desaturase
ETL58_RS10715	COG4585	Histidine kinase
ETL58_RS10720	COG2197	response regulator
ETL58_RS10725	COG1388	LysM domain
ETL58_RS10725	COG3584	3D domain protein
ETL58_RS10730	COG0514	ATP-dependent DNA helicase (RecQ)
ETL58_RS10745	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ETL58_RS10750	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ETL58_RS10765	COG0071	Belongs to the small heat shock protein (HSP20) family
ETL58_RS10790	COG1012	belongs to the aldehyde dehydrogenase family
ETL58_RS10795	COG1657	PFAM Prenyltransferase squalene oxidase
ETL58_RS10800	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ETL58_RS10805	COG0733	neurotransmitter:sodium symporter activity
ETL58_RS10810	COG0385	Bile acid
ETL58_RS10815	COG0508	dehydrogenase complex catalyzes the overall conversion of
ETL58_RS10820	COG0567	Dehydrogenase, E1 component
ETL58_RS10825	COG4548	von Willebrand factor, type A
ETL58_RS10830	COG0714	Associated with various cellular activities
ETL58_RS10835	COG2032	superoxide dismutase activity
ETL58_RS10840	COG0791	NLP P60 protein
ETL58_RS10840	COG1388	LysM domain
ETL58_RS10845	COG1819	glycosyl
ETL58_RS10850	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ETL58_RS10855	COG0534	Mate efflux family protein
ETL58_RS10860	COG1366	Belongs to the anti-sigma-factor antagonist family
ETL58_RS10865	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ETL58_RS10870	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ETL58_RS10880	COG2962	Rard protein
ETL58_RS10895	COG2610	gluconate transmembrane transporter activity
ETL58_RS10900	COG1942	4-Oxalocrotonate Tautomerase
ETL58_RS10905	COG1733	regulation of RNA biosynthetic process
ETL58_RS10910	COG0778	Nitroreductase
ETL58_RS10915	COG0400	carboxylic ester hydrolase activity
ETL58_RS10920	COG0346	lactoylglutathione lyase activity
ETL58_RS10930	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ETL58_RS10935	COG3409	Peptidoglycan-binding domain 1 protein
ETL58_RS10935	COG0793	Belongs to the peptidase S41A family
ETL58_RS10940	COG2226	methyltransferase
ETL58_RS10950	COG1876	peptidase activity
ETL58_RS10955	COG0813	purine-nucleoside phosphorylase activity
ETL58_RS10970	COG0671	phosphoesterase, PA-phosphatase related
ETL58_RS10995	COG4479	Belongs to the UPF0346 family
ETL58_RS11005	COG1509	lysine 2,3-aminomutase activity
ETL58_RS11010	COG0456	acetyltransferase
ETL58_RS11015	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ETL58_RS11020	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ETL58_RS11025	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ETL58_RS11030	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ETL58_RS11045	COG0456	acetyltransferase
ETL58_RS11050	COG0463	Glycosyl transferase, family 2
ETL58_RS11065	COG4641	Protein conserved in bacteria
ETL58_RS11070	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
ETL58_RS11075	COG1086	Polysaccharide biosynthesis protein
ETL58_RS11080	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ETL58_RS11085	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ETL58_RS11090	COG1846	Transcriptional regulator
ETL58_RS11095	COG0534	Mate efflux family protein
ETL58_RS11105	COG4698	Protein conserved in bacteria
ETL58_RS11110	COG2755	lipolytic protein G-D-S-L family
ETL58_RS11115	COG1999	signal sequence binding
ETL58_RS11125	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ETL58_RS11130	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ETL58_RS11135	COG1272	protein, Hemolysin III
ETL58_RS11140	COG0204	Acyl-transferase
ETL58_RS11145	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ETL58_RS11150	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ETL58_RS11155	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ETL58_RS11165	COG2136	Putative SAM-dependent methyltransferase
ETL58_RS11165	COG2521	methyltransferase
ETL58_RS11175	COG0129	dihydroxy-acid dehydratase activity
ETL58_RS11180	COG1413	lyase activity
ETL58_RS11185	COG1418	mRNA catabolic process
ETL58_RS11190	COG0386	Belongs to the glutathione peroxidase family
ETL58_RS11195	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
ETL58_RS11200	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ETL58_RS11210	COG1278	Cold shock
ETL58_RS11230	COG0328	RNA-DNA hybrid ribonuclease activity
ETL58_RS11235	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ETL58_RS11240	COG0328	RNA-DNA hybrid ribonuclease activity
ETL58_RS11250	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ETL58_RS11265	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ETL58_RS11275	COG1755	Isoprenylcysteine carboxyl methyltransferase
ETL58_RS11280	COG3424	synthase
ETL58_RS11285	COG2233	PERMEase
ETL58_RS11290	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ETL58_RS11295	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
ETL58_RS11305	COG0800	Aldolase
ETL58_RS11310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ETL58_RS11315	COG1609	Transcriptional regulator
ETL58_RS11320	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
ETL58_RS11325	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_RS11330	COG1199	ATP-dependent helicase activity
ETL58_RS11345	COG0116	Belongs to the methyltransferase superfamily
ETL58_RS11360	COG4474	Belongs to the UPF0398 family
ETL58_RS11375	COG3359	exonuclease
ETL58_RS11380	COG1205	dead DEAH box helicase
ETL58_RS11380	COG1111	helicase
ETL58_RS11385	COG2190	(PTS) system
ETL58_RS11390	COG0071	Belongs to the small heat shock protein (HSP20) family
ETL58_RS11425	COG3331	DNA recombination
ETL58_RS11430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ETL58_RS11430	COG4499	WXG100 protein secretion system (Wss), protein YukC
ETL58_RS11440	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ETL58_RS11445	COG3935	DnaD domain protein
ETL58_RS11450	COG0017	Asparaginyl-tRNA synthetase
ETL58_RS11455	COG0436	Aminotransferase
ETL58_RS11460	COG5353	protein conserved in bacteria
ETL58_RS11470	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ETL58_RS11470	COG1199	ATP-dependent helicase activity
ETL58_RS11475	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ETL58_RS11480	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ETL58_RS11485	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ETL58_RS11490	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ETL58_RS11490	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ETL58_RS11495	COG0617	tRNA 3'-terminal CCA addition
ETL58_RS11500	COG0438	transferase activity, transferring glycosyl groups
ETL58_RS11505	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ETL58_RS11510	COG1803	Methylglyoxal synthase
ETL58_RS11515	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ETL58_RS11520	COG1694	Mazg nucleotide pyrophosphohydrolase
ETL58_RS11525	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETL58_RS11535	COG4347	Protein of unknown function (DUF1405)
ETL58_RS11540	COG2010	Cytochrome c
ETL58_RS11540	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ETL58_RS11545	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ETL58_RS11550	COG0723	plastoquinol--plastocyanin reductase activity
ETL58_RS11560	COG5582	Belongs to the UPF0302 family
ETL58_RS11565	COG0457	Tetratricopeptide repeat
ETL58_RS11570	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ETL58_RS11575	COG0287	Prephenate dehydrogenase
ETL58_RS11580	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ETL58_RS11585	COG0159	tryptophan synthase activity
ETL58_RS11590	COG0133	tryptophan synthase activity
ETL58_RS11595	COG0135	phosphoribosylanthranilate isomerase activity
ETL58_RS11605	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ETL58_RS11610	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ETL58_RS11615	COG4401	Chorismate mutase type I
ETL58_RS11620	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ETL58_RS11625	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ETL58_RS11630	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ETL58_RS11635	COG0105	UTP biosynthetic process
ETL58_RS11640	COG0142	geranyltranstransferase activity
ETL58_RS11645	COG2226	methyltransferase
ETL58_RS11650	COG0142	geranyltranstransferase activity
ETL58_RS11660	COG0302	gtp cyclohydrolase
ETL58_RS11665	COG0776	regulation of translation
ETL58_RS11670	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ETL58_RS11685	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ETL58_RS11690	COG1160	GTP binding
ETL58_RS11715	COG1304	FMN binding
ETL58_RS11720	COG0539	negative regulation of cytoplasmic translation
ETL58_RS11725	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ETL58_RS11735	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
ETL58_RS11740	COG2959	enzyme of heme biosynthesis
ETL58_RS11745	COG3409	Peptidoglycan-binding domain 1 protein
ETL58_RS11745	COG3773	Cell wall hydrolase
ETL58_RS11750	COG2339	peptidase activity
ETL58_RS11755	COG0492	ferredoxin-NADP+ reductase activity
ETL58_RS11760	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ETL58_RS11765	COG4862	establishment of competence for transformation
ETL58_RS11770	COG1408	metallophosphoesterase
ETL58_RS11780	COG1388	LysM domain
ETL58_RS11785	COG1266	CAAX protease self-immunity
ETL58_RS11790	COG0514	ATP-dependent DNA helicase (RecQ)
ETL58_RS11795	COG4955	Helix-turn-helix domain
ETL58_RS11800	COG1141	Ferredoxin
ETL58_RS11805	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
ETL58_RS11810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ETL58_RS11815	COG0710	3-dehydroquinate dehydratase activity
ETL58_RS11825	COG1595	DNA-templated transcription, initiation
ETL58_RS11830	COG5002	protein histidine kinase activity
ETL58_RS11835	COG0745	RESPONSE REGULATOR receiver
ETL58_RS11840	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ETL58_RS11845	COG1333	cytochrome c biogenesis protein
ETL58_RS11850	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETL58_RS11855	COG1187	pseudouridine synthase activity
ETL58_RS11860	COG0700	Nucleoside recognition
ETL58_RS11865	COG2715	membrane protein required for spore maturation
ETL58_RS11870	COG1686	Belongs to the peptidase S11 family
ETL58_RS11880	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ETL58_RS11885	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ETL58_RS11890	COG1547	Domain of unknown function (DUF309)
ETL58_RS11895	COG0456	acetyltransferase
ETL58_RS11900	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ETL58_RS11905	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ETL58_RS11905	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ETL58_RS11910	COG0307	riboflavin synthase, alpha
ETL58_RS11915	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ETL58_RS11915	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ETL58_RS11925	COG0681	Belongs to the peptidase S26 family
ETL58_RS11935	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
ETL58_RS11955	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ETL58_RS11965	COG4086	secreted protein
ETL58_RS11970	COG0019	diaminopimelate decarboxylase activity
ETL58_RS11975	COG0697	spore germination
ETL58_RS11990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ETL58_RS12010	COG1191	sigma factor activity
ETL58_RS12015	COG2172	sigma factor antagonist activity
ETL58_RS12020	COG1366	Belongs to the anti-sigma-factor antagonist family
ETL58_RS12025	COG1686	Belongs to the peptidase S11 family
ETL58_RS12030	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ETL58_RS12035	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ETL58_RS12040	COG4974	Belongs to the 'phage' integrase family
ETL58_RS12050	COG0735	belongs to the Fur family
ETL58_RS12055	COG1300	Membrane
ETL58_RS12065	COG0281	malic enzyme
ETL58_RS12070	COG1757	Na H antiporter
ETL58_RS12075	COG1027	Aspartate ammonia-lyase
ETL58_RS12080	COG0252	asparaginase activity
ETL58_RS12085	COG1396	sequence-specific DNA binding
ETL58_RS12090	COG1379	DNA repair
ETL58_RS12095	COG0494	nUDIX hydrolase
ETL58_RS12105	COG0667	Aldo Keto reductase
ETL58_RS12115	COG1073	alpha beta
ETL58_RS12125	COG4918	Iron-sulphur cluster biosynthesis
ETL58_RS12130	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ETL58_RS12130	COG0456	acetyltransferase
ETL58_RS12135	COG2329	Antibiotic biosynthesis monooxygenase
ETL58_RS12140	COG0456	acetyltransferase
ETL58_RS12150	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ETL58_RS12160	COG2211	Major facilitator Superfamily
ETL58_RS12165	COG0346	lactoylglutathione lyase activity
ETL58_RS12170	COG1072	(Pantothenic acid kinase))
ETL58_RS12175	COG3048	D-serine ammonia-lyase activity
ETL58_RS12180	COG0300	oxidoreductase activity
ETL58_RS12185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETL58_RS12190	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ETL58_RS12195	COG4187	Peptidase family M20/M25/M40
ETL58_RS12200	COG1902	pentaerythritol trinitrate reductase activity
ETL58_RS12205	COG0596	Alpha beta hydrolase
ETL58_RS12215	COG1234	tRNA 3'-trailer cleavage
ETL58_RS12220	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ETL58_RS12225	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ETL58_RS12230	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ETL58_RS12240	COG0706	membrane insertase activity
ETL58_RS12245	COG3361	conserved protein (COG2071)
ETL58_RS12250	COG2195	Cleaves the N-terminal amino acid of tripeptides
ETL58_RS12255	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ETL58_RS12260	COG0346	lactoylglutathione lyase activity
ETL58_RS12265	COG1376	ErfK ybiS ycfS ynhG family protein
ETL58_RS12270	COG4129	membrane
ETL58_RS12275	COG1126	abc transporter atp-binding protein
ETL58_RS12280	COG0765	amino acid transport
ETL58_RS12285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETL58_RS12295	COG1597	lipid kinase activity
ETL58_RS12300	COG2814	Major facilitator Superfamily
ETL58_RS12305	COG0789	Transcriptional regulator
ETL58_RS12305	COG4978	Transcriptional regulator
ETL58_RS12310	COG0508	dehydrogenase complex catalyzes the overall conversion of
ETL58_RS12315	COG0022	dehydrogenase e1 component
ETL58_RS12320	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ETL58_RS12325	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ETL58_RS12330	COG3426	butyrate kinase activity
ETL58_RS12335	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ETL58_RS12340	COG0280	phosphate acetyltransferase
ETL58_RS12345	COG3290	protein histidine kinase activity
ETL58_RS12345	COG3829	transcription factor binding
ETL58_RS12355	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ETL58_RS12360	COG2079	MmgE PrpD family protein
ETL58_RS12365	COG0372	Belongs to the citrate synthase family
ETL58_RS12370	COG1960	acyl-CoA dehydrogenase activity
ETL58_RS12375	COG1250	3-hydroxyacyl-CoA dehydrogenase
ETL58_RS12380	COG0183	Belongs to the thiolase family
ETL58_RS12385	COG0584	glycerophosphoryl diester phosphodiesterase
ETL58_RS12390	COG0860	N-Acetylmuramoyl-L-alanine amidase
ETL58_RS12405	COG1902	pentaerythritol trinitrate reductase activity
ETL58_RS12410	COG0745	RESPONSE REGULATOR receiver
ETL58_RS12415	COG0750	zinc metalloprotease
ETL58_RS12420	COG0497	DNA recombination
ETL58_RS12425	COG1438	arginine binding
ETL58_RS12430	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
ETL58_RS12435	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ETL58_RS12440	COG0142	geranyltranstransferase activity
ETL58_RS12445	COG1722	exodeoxyribonuclease VII activity
ETL58_RS12450	COG1570	exodeoxyribonuclease VII activity
ETL58_RS12455	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ETL58_RS12460	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ETL58_RS12465	COG1302	Protein conserved in bacteria
ETL58_RS12470	COG0439	Biotin carboxylase
ETL58_RS12475	COG0511	ligase activity, forming carbon-carbon bonds
ETL58_RS12515	COG3854	ATPases associated with a variety of cellular activities
ETL58_RS12525	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ETL58_RS12530	COG0006	proline dipeptidase activity
ETL58_RS12535	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ETL58_RS12545	COG3872	metal-dependent enzyme
ETL58_RS12555	COG1752	Esterase of the alpha-beta hydrolase superfamily
ETL58_RS12560	COG1321	iron dependent repressor
ETL58_RS12565	COG0095	Lipoate-protein ligase
ETL58_RS12570	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ETL58_RS12575	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ETL58_RS12580	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ETL58_RS12585	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ETL58_RS12590	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ETL58_RS12605	COG1396	sequence-specific DNA binding
ETL58_RS12615	COG0681	Belongs to the peptidase S26 family
ETL58_RS12640	COG4940	Competence protein ComGF
ETL58_RS12650	COG4970	Tfp pilus assembly protein FimT
ETL58_RS12655	COG4537	Required for transformation and DNA binding
ETL58_RS12660	COG1459	type II secretion system
ETL58_RS12665	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ETL58_RS12675	COG0598	Magnesium transport protein CorA
ETL58_RS12680	COG1253	flavin adenine dinucleotide binding
ETL58_RS12685	COG1366	Belongs to the anti-sigma-factor antagonist family
ETL58_RS12695	COG1393	Belongs to the ArsC family
ETL58_RS12705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETL58_RS12715	COG0011	TIGRFAM Protein of
ETL58_RS12725	COG2866	Carboxypeptidase
ETL58_RS12730	COG1368	sulfuric ester hydrolase activity
ETL58_RS12735	COG1940	carbohydrate kinase activity
ETL58_RS12740	COG4483	Protein conserved in bacteria
ETL58_RS12745	COG0705	Rhomboid family
ETL58_RS12745	COG0457	Tetratricopeptide repeat
ETL58_RS12755	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ETL58_RS12765	COG0438	transferase activity, transferring glycosyl groups
ETL58_RS12780	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ETL58_RS12785	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ETL58_RS12790	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ETL58_RS12795	COG0581	inorganic phosphate transmembrane transporter activity
ETL58_RS12800	COG0573	inorganic phosphate transmembrane transporter activity
ETL58_RS12805	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ETL58_RS12810	COG0768	penicillin binding
ETL58_RS12815	COG0477	Major facilitator Superfamily
ETL58_RS12820	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ETL58_RS12825	COG2839	Protein conserved in bacteria
ETL58_RS12830	COG5521	maltodextrose utilization protein MalA
ETL58_RS12835	COG1388	LysM domain
ETL58_RS12840	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ETL58_RS12845	COG4709	membrane
ETL58_RS12850	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
ETL58_RS12855	COG0735	belongs to the Fur family
ETL58_RS12860	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETL58_RS12870	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ETL58_RS12875	COG0513	Belongs to the DEAD box helicase family
ETL58_RS12885	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ETL58_RS12890	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ETL58_RS12895	COG2384	SAM-dependent methyltransferase
ETL58_RS12900	COG2010	Cytochrome c
ETL58_RS12910	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ETL58_RS12915	COG0358	DNA primase activity
ETL58_RS12920	COG1671	Belongs to the UPF0178 family
ETL58_RS12925	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ETL58_RS12930	COG0517	IMP dehydrogenase activity
ETL58_RS12935	COG0751	glycine-tRNA ligase activity
ETL58_RS12940	COG0752	glycyl-tRNA synthetase alpha subunit
ETL58_RS12945	COG1381	Involved in DNA repair and RecF pathway recombination
ETL58_RS12955	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ETL58_RS12960	COG0295	cytidine deaminase activity
ETL58_RS12965	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ETL58_RS12970	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ETL58_RS12975	COG1480	7TM receptor with intracellular HD hydrolase
ETL58_RS12980	COG1702	phosphate starvation-inducible protein PhoH
ETL58_RS12985	COG0561	phosphatase activity
ETL58_RS13000	COG4864	UPF0365 protein
ETL58_RS13005	COG1030	water channel activity
ETL58_RS13010	COG1610	YqeY-like protein
ETL58_RS13020	COG1283	sodium-dependent phosphate transmembrane transporter activity
ETL58_RS13025	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ETL58_RS13030	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ETL58_RS13035	COG2264	protein methyltransferase activity
ETL58_RS13040	COG0484	heat shock protein binding
ETL58_RS13045	COG0443	Heat shock 70 kDa protein
ETL58_RS13050	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ETL58_RS13055	COG1420	regulation of RNA biosynthetic process
ETL58_RS13060	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ETL58_RS13065	COG0481	GTPase activity
ETL58_RS13075	COG0860	N-Acetylmuramoyl-L-alanine amidase
ETL58_RS13080	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ETL58_RS13085	COG0268	Binds directly to 16S ribosomal RNA
ETL58_RS13090	COG1466	dna polymerase III delta subunit
ETL58_RS13105	COG2333	competence protein COMEC
ETL58_RS13105	COG0658	competence protein
ETL58_RS13110	COG2131	deaminase
ETL58_RS13115	COG1555	photosystem II stabilization
ETL58_RS13115	COG1596	polysaccharide export
ETL58_RS13120	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ETL58_RS13125	COG2226	methyltransferase
ETL58_RS13130	COG0799	negative regulation of ribosome biogenesis
ETL58_RS13135	COG1713	HD superfamily hydrolase involved in NAD metabolism
ETL58_RS13140	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ETL58_RS13145	COG1534	Rna-binding protein
ETL58_RS13150	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ETL58_RS13155	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ETL58_RS13160	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
ETL58_RS13170	COG2755	lipolytic protein G-D-S-L family
ETL58_RS13175	COG3409	Peptidoglycan-binding domain 1 protein
ETL58_RS13175	COG5632	N-Acetylmuramoyl-L-alanine amidase
ETL58_RS13180	COG0398	Pfam SNARE associated Golgi protein
ETL58_RS13185	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
ETL58_RS13195	COG3209	COG3209 Rhs family protein
ETL58_RS13205	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ETL58_RS13215	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ETL58_RS13220	COG0798	PFAM Bile acid sodium symporter
ETL58_RS13225	COG0346	lactoylglutathione lyase activity
ETL58_RS13230	COG0640	Transcriptional regulator
ETL58_RS13235	COG3403	YqcI/YcgG family
ETL58_RS13240	COG0457	Tetratricopeptide repeat
ETL58_RS13255	COG5444	nuclease activity
ETL58_RS13260	COG4282	regulation of fungal-type cell wall biogenesis
ETL58_RS13290	COG3409	Peptidoglycan-binding domain 1 protein
ETL58_RS13290	COG5632	N-Acetylmuramoyl-L-alanine amidase
ETL58_RS13295	COG4824	toxin secretion phage lysis holin
ETL58_RS13325	COG3778	Protein conserved in bacteria
ETL58_RS13330	COG3299	homolog of phage Mu protein gp47
ETL58_RS13335	COG3628	GPW Gp25 family protein
ETL58_RS13345	COG4193	domain, Protein
ETL58_RS13350	COG1652	LysM domain
ETL58_RS13355	COG3953	SLT domain
ETL58_RS13355	COG5280	Phage tail tape measure protein TP901
ETL58_RS13420	COG4653	Phage capsid family
ETL58_RS13425	COG0338	D12 class N6 adenine-specific DNA methyltransferase
ETL58_RS13435	COG2369	cell adhesion
ETL58_RS13440	COG5518	Phage portal protein
ETL58_RS13445	COG1783	phage Terminase large subunit
ETL58_RS13450	COG5484	DNA packaging
ETL58_RS13465	COG3677	Transposase
ETL58_RS13485	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
ETL58_RS13495	COG1484	DNA-dependent DNA replication
ETL58_RS13500	COG3935	DnaD domain protein
ETL58_RS13505	COG3723	Recombinational DNA repair protein, rece pathway
ETL58_RS13510	COG5377	YqaJ viral recombinase family
ETL58_RS13545	COG3620	sequence-specific DNA binding
ETL58_RS13555	COG0563	adenylate kinase activity
ETL58_RS13560	COG2856	Zn peptidase
ETL58_RS13585	COG3223	Belongs to the PsiE family
ETL58_RS13590	COG0642	Histidine kinase
ETL58_RS13590	COG5002	protein histidine kinase activity
ETL58_RS13595	COG0745	RESPONSE REGULATOR receiver
ETL58_RS13600	COG2311	Membrane
ETL58_RS13610	COG0454	-acetyltransferase
ETL58_RS13615	COG2249	NAD(P)H dehydrogenase (quinone) activity
ETL58_RS13625	COG0730	response to heat
ETL58_RS13630	COG0425	Belongs to the sulfur carrier protein TusA family
ETL58_RS13635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETL58_RS13635	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ETL58_RS13645	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ETL58_RS13645	COG0425	Belongs to the sulfur carrier protein TusA family
ETL58_RS13655	COG2210	Belongs to the sulfur carrier protein TusA family
ETL58_RS13660	COG1937	Protein conserved in bacteria
ETL58_RS13675	COG0662	Cupin 2, conserved barrel domain protein
ETL58_RS13690	COG4978	Transcriptional regulator
ETL58_RS13690	COG0789	Transcriptional regulator
ETL58_RS13695	COG2814	Major facilitator Superfamily
ETL58_RS13700	COG0456	acetyltransferase
ETL58_RS13705	COG1253	flavin adenine dinucleotide binding
ETL58_RS13715	COG0697	spore germination
ETL58_RS13720	COG0583	DNA-binding transcription factor activity
ETL58_RS13725	COG2072	flavoprotein involved in K transport
ETL58_RS13730	COG1230	cation diffusion facilitator family transporter
ETL58_RS13735	COG1942	4-Oxalocrotonate Tautomerase
ETL58_RS13740	COG0583	DNA-binding transcription factor activity
ETL58_RS13750	COG1114	Component of the transport system for branched-chain amino acids
ETL58_RS13755	COG1687	branched-chain amino acid
ETL58_RS13760	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ETL58_RS13765	COG1522	sequence-specific DNA binding
ETL58_RS13775	COG2124	cytochrome p450
ETL58_RS13780	COG1335	isochorismatase
ETL58_RS13795	COG2318	DinB family
ETL58_RS13805	COG2070	2-Nitropropane dioxygenase
ETL58_RS13840	COG3443	Belongs to the bacterial solute-binding protein 9 family
ETL58_RS13845	COG1595	DNA-templated transcription, initiation
ETL58_RS13850	COG0667	Aldo Keto reductase
ETL58_RS13855	COG2851	Citrate transporter
ETL58_RS13860	COG0583	DNA-binding transcription factor activity
ETL58_RS13865	COG2828	Protein conserved in bacteria
ETL58_RS13870	COG3409	Peptidoglycan-binding domain 1 protein
ETL58_RS13875	COG5566	PFAM Mor transcription activator
ETL58_RS13880	COG0596	Alpha beta hydrolase
ETL58_RS13885	COG4991	sh3 domain protein
ETL58_RS13890	COG4991	sh3 domain protein
ETL58_RS13900	COG0346	lactoylglutathione lyase activity
ETL58_RS13910	COG5577	PFAM Coat F domain
ETL58_RS13915	COG1063	alcohol dehydrogenase
ETL58_RS13925	COG5577	PFAM Coat F domain
ETL58_RS13930	COG0789	Transcriptional regulator
ETL58_RS13940	COG1064	alcohol dehydrogenase
ETL58_RS13945	COG0693	protein deglycase activity
ETL58_RS13950	COG1621	beta-fructofuranosidase activity
ETL58_RS13955	COG3716	PTS system mannose fructose sorbose family IID component
ETL58_RS13960	COG3715	PTS system
ETL58_RS13965	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETL58_RS13970	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETL58_RS13975	COG3933	PFAM sigma-54 factor interaction domain-containing protein
ETL58_RS13975	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ETL58_RS13985	COG1113	amino acid transport
ETL58_RS13990	COG1280	lysine exporter protein (LysE YggA)
ETL58_RS13995	COG1378	Sugar-specific transcriptional regulator TrmB
ETL58_RS14000	COG1595	DNA-templated transcription, initiation
ETL58_RS14010	COG2755	lipolytic protein G-D-S-L family
ETL58_RS14010	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ETL58_RS14020	COG2124	cytochrome p450
ETL58_RS14020	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ETL58_RS14025	COG1309	transcriptional regulator
ETL58_RS14030	COG2226	methyltransferase
ETL58_RS14045	COG2116	formate transmembrane transporter activity
ETL58_RS14050	COG5609	conserved protein (DUF2294)
ETL58_RS14055	COG3383	formate dehydrogenase (NAD+) activity
ETL58_RS14060	COG2427	Protein of unknown function (DUF1641)
ETL58_RS14070	COG0626	cystathionine gamma-synthase activity
ETL58_RS14075	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ETL58_RS14080	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ETL58_RS14085	COG2226	methyltransferase
ETL58_RS14100	COG0768	penicillin binding
ETL58_RS14105	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ETL58_RS14110	COG0572	uridine kinase
ETL58_RS14115	COG0826	peptidase U32
ETL58_RS14120	COG0826	peptidase U32
ETL58_RS14125	COG4122	O-methyltransferase activity
ETL58_RS14130	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ETL58_RS14135	COG3906	Belongs to the UPF0473 family
ETL58_RS14140	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ETL58_RS14145	COG4472	Bacterial protein of unknown function (DUF965)
ETL58_RS14150	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ETL58_RS14155	COG0628	permease
ETL58_RS14160	COG1126	abc transporter atp-binding protein
ETL58_RS14165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETL58_RS14170	COG0765	amino acid transport
ETL58_RS14175	COG0765	amino acid transport
ETL58_RS14190	COG3881	PFAM PRC-barrel domain
ETL58_RS14195	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ETL58_RS14200	COG0457	Tetratricopeptide repeat
ETL58_RS14205	COG0482	sulfurtransferase activity
ETL58_RS14210	COG1104	cysteine desulfurase activity
ETL58_RS14215	COG1959	2 iron, 2 sulfur cluster binding
ETL58_RS14220	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ETL58_RS14225	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ETL58_RS14235	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ETL58_RS14240	COG0124	histidyl-tRNA synthetase
ETL58_RS14250	COG0860	N-Acetylmuramoyl-L-alanine amidase
ETL58_RS14250	COG4991	sh3 domain protein
ETL58_RS14250	COG3103	Sh3 type 3 domain protein
ETL58_RS14255	COG1490	D-aminoacyl-tRNA deacylase activity
ETL58_RS14260	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ETL58_RS14265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ETL58_RS14270	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ETL58_RS14270	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ETL58_RS14275	COG5416	Lipopolysaccharide assembly protein A domain
ETL58_RS14280	COG0490	domain, Protein
ETL58_RS14285	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ETL58_RS14285	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ETL58_RS14295	COG2244	polysaccharide biosynthetic process
ETL58_RS14300	COG2323	membrane
ETL58_RS14310	COG1862	Preprotein translocase
ETL58_RS14315	COG0343	queuine tRNA-ribosyltransferase activity
ETL58_RS14320	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ETL58_RS14330	COG2255	four-way junction helicase activity
ETL58_RS14335	COG0632	four-way junction helicase activity
ETL58_RS14345	COG2814	Major facilitator Superfamily
ETL58_RS14350	COG0673	inositol 2-dehydrogenase activity
ETL58_RS14355	COG2112	serine threonine protein kinase
ETL58_RS14375	COG1115	amino acid carrier protein
ETL58_RS14380	COG0217	transcriptional regulatory protein
ETL58_RS14390	COG1388	LysM domain
ETL58_RS14395	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ETL58_RS14400	COG0157	Belongs to the NadC ModD family
ETL58_RS14405	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ETL58_RS14410	COG1104	cysteine desulfurase activity
ETL58_RS14415	COG1827	regulation of RNA biosynthetic process
ETL58_RS14420	COG0077	Prephenate dehydratase
ETL58_RS14425	COG4492	Belongs to the UPF0735 family
ETL58_RS14430	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ETL58_RS14435	COG3290	protein histidine kinase activity
ETL58_RS14445	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ETL58_RS14450	COG2868	ribosomal protein
ETL58_RS14455	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ETL58_RS14460	COG1994	Peptidase M50
ETL58_RS14465	COG0739	heme binding
ETL58_RS14470	COG2894	cell division
ETL58_RS14475	COG0850	regulation of cytokinetic process
ETL58_RS14480	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ETL58_RS14490	COG1077	Cell shape determining protein MreB Mrl
ETL58_RS14495	COG2003	Belongs to the UPF0758 family
ETL58_RS14500	COG0424	maF-like protein
ETL58_RS14510	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ETL58_RS14515	COG0285	dihydrofolate synthase activity
ETL58_RS14520	COG0525	valine-tRNA ligase activity
ETL58_RS14530	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ETL58_RS14535	COG1388	LysM domain
ETL58_RS14540	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ETL58_RS14545	COG0113	porphobilinogen synthase activity
ETL58_RS14550	COG1587	Uroporphyrinogen-III synthase
ETL58_RS14555	COG0181	hydroxymethylbilane synthase activity
ETL58_RS14560	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ETL58_RS14565	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ETL58_RS14575	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ETL58_RS14580	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ETL58_RS14585	COG0470	DNA polymerase III
ETL58_RS14585	COG1067	ATP-dependent peptidase activity
ETL58_RS14590	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ETL58_RS14595	COG0544	peptidyl-prolyl cis-trans isomerase activity
ETL58_RS14600	COG0457	Tetratricopeptide repeat
ETL58_RS14600	COG1477	protein flavinylation
ETL58_RS14605	COG0066	3-isopropylmalate dehydratase activity
ETL58_RS14610	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ETL58_RS14615	COG0473	3-isopropylmalate dehydrogenase activity
ETL58_RS14620	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ETL58_RS14625	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ETL58_RS14630	COG0440	acetolactate synthase activity
ETL58_RS14635	COG0028	Belongs to the TPP enzyme family
ETL58_RS14645	COG0454	-acetyltransferase
ETL58_RS14655	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
ETL58_RS14665	COG0622	Phosphoesterase
ETL58_RS14670	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ETL58_RS14675	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ETL58_RS14680	COG5401	PFAM Sporulation and spore germination
ETL58_RS14685	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ETL58_RS14690	COG1846	Transcriptional regulator
ETL58_RS14695	COG2197	response regulator
ETL58_RS14700	COG0824	Thioesterase
ETL58_RS14705	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ETL58_RS14710	COG1053	succinate dehydrogenase
ETL58_RS14715	COG2009	succinate dehydrogenase
ETL58_RS14720	COG1719	4-vinyl reductase, 4VR
ETL58_RS14725	COG0527	aspartate kinase activity
ETL58_RS14735	COG0322	excinuclease ABC activity
ETL58_RS14740	COG3118	belongs to the thioredoxin family
ETL58_RS14750	COG3534	alpha-L-arabinofuranosidase
ETL58_RS14755	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ETL58_RS14760	COG2086	electron transfer activity
ETL58_RS14765	COG1024	Enoyl-CoA hydratase
ETL58_RS14770	COG1309	transcriptional regulator
ETL58_RS14775	COG0318	PFAM AMP-dependent synthetase and ligase
ETL58_RS14780	COG3766	membrane
ETL58_RS14785	COG1193	negative regulation of DNA recombination
ETL58_RS14790	COG1796	DNA polymerase
ETL58_RS14790	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ETL58_RS14795	COG1286	toxin biosynthetic process
ETL58_RS14800	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
ETL58_RS14805	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ETL58_RS14810	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ETL58_RS14810	COG0072	phenylalanine-tRNA ligase activity
ETL58_RS14815	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ETL58_RS14825	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ETL58_RS14835	COG3835	regulator
ETL58_RS14840	COG0277	FAD linked oxidase domain protein
ETL58_RS14845	COG0247	lactate metabolic process
ETL58_RS14850	COG0346	lactoylglutathione lyase activity
ETL58_RS14860	COG1966	Carbon starvation protein
ETL58_RS14865	COG3534	alpha-L-arabinofuranosidase
ETL58_RS14870	COG0395	ABC-type sugar transport system, permease component
ETL58_RS14875	COG1175	transmembrane transport
ETL58_RS14880	COG1653	transport
ETL58_RS14885	COG0371	Dehydrogenase
ETL58_RS14890	COG0647	UMP catabolic process
ETL58_RS14895	COG0235	Class ii aldolase
ETL58_RS14900	COG1069	ribulokinase activity
ETL58_RS14905	COG2160	L-arabinose isomerase activity
ETL58_RS14910	COG3507	Belongs to the glycosyl hydrolase 43 family
ETL58_RS14915	COG1363	Peptidase, m42
ETL58_RS14925	COG3326	Membrane
ETL58_RS14930	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ETL58_RS14935	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ETL58_RS14940	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ETL58_RS14950	COG1346	cytolysis
ETL58_RS14955	COG1380	Effector of murein hydrolase LrgA
ETL58_RS14960	COG3279	Response regulator of the LytR AlgR family
ETL58_RS14965	COG3275	phosphorelay sensor kinase activity
ETL58_RS14970	COG1011	Hydrolase
ETL58_RS14975	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ETL58_RS14985	COG0398	Pfam SNARE associated Golgi protein
ETL58_RS14990	COG1484	DNA-dependent DNA replication
ETL58_RS14995	COG3611	Membrane attachment protein
ETL58_RS15000	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ETL58_RS15005	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ETL58_RS15010	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ETL58_RS15015	COG1733	regulation of RNA biosynthetic process
ETL58_RS15020	COG2814	Major facilitator Superfamily
ETL58_RS15025	COG0656	L-ascorbic acid biosynthetic process
ETL58_RS15030	COG0237	dephospho-CoA kinase activity
ETL58_RS15035	COG1971	Probably functions as a manganese efflux pump
ETL58_RS15040	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ETL58_RS15045	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ETL58_RS15045	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ETL58_RS15050	COG5002	protein histidine kinase activity
ETL58_RS15055	COG0745	RESPONSE REGULATOR receiver
ETL58_RS15060	COG0039	L-malate dehydrogenase activity
ETL58_RS15065	COG0538	isocitrate dehydrogenase activity
ETL58_RS15070	COG0372	Belongs to the citrate synthase family
ETL58_RS15075	COG2707	UPF0756 membrane protein
ETL58_RS15080	COG0628	permease
ETL58_RS15085	COG3030	protein affecting phage T7 exclusion by the F plasmid
ETL58_RS15090	COG0469	pyruvate kinase activity
ETL58_RS15095	COG0205	6-phosphofructokinase activity
ETL58_RS15100	COG0825	malonyl-CoA metabolic process
ETL58_RS15105	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ETL58_RS15110	COG0281	malic enzyme
ETL58_RS15115	COG0587	DNA-directed DNA polymerase activity
ETL58_RS15135	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ETL58_RS15145	COG4109	DRTGG domain
ETL58_RS15150	COG0730	response to heat
ETL58_RS15155	COG1473	amidohydrolase
ETL58_RS15160	COG0196	riboflavin kinase activity
ETL58_RS15165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ETL58_RS15170	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ETL58_RS15175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ETL58_RS15180	COG1126	abc transporter atp-binding protein
ETL58_RS15185	COG0765	amino acid transport
ETL58_RS15190	COG0765	amino acid transport
ETL58_RS15195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETL58_RS15200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETL58_RS15205	COG0454	-acetyltransferase
ETL58_RS15210	COG0583	DNA-binding transcription factor activity
ETL58_RS15215	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ETL58_RS15220	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_RS15230	COG0165	Argininosuccinate lyase
ETL58_RS15235	COG0137	argininosuccinate synthase activity
ETL58_RS15240	COG0521	Mo-molybdopterin cofactor biosynthetic process
ETL58_RS15245	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ETL58_RS15255	COG0827	DNA restriction-modification system
ETL58_RS15260	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ETL58_RS15265	COG3874	Sporulation protein YtfJ
ETL58_RS15275	COG1714	RDD family
ETL58_RS15280	COG0616	signal peptide processing
ETL58_RS15285	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ETL58_RS15290	COG1574	metal-dependent hydrolase with the TIM-barrel fold
ETL58_RS15295	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ETL58_RS15305	COG0301	tRNA thio-modification
ETL58_RS15310	COG1104	cysteine desulfurase activity
ETL58_RS15315	COG1114	Component of the transport system for branched-chain amino acids
ETL58_RS15320	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
ETL58_RS15325	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ETL58_RS15330	COG1309	transcriptional regulator
ETL58_RS15335	COG1956	GAF domain-containing protein
ETL58_RS15340	COG2199	diguanylate cyclase activity
ETL58_RS15340	COG2203	Gaf domain
ETL58_RS15350	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ETL58_RS15355	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ETL58_RS15360	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ETL58_RS15365	COG0454	-acetyltransferase
ETL58_RS15370	COG0517	IMP dehydrogenase activity
ETL58_RS15375	COG0123	including yeast histone deacetylase and acetoin utilization protein
ETL58_RS15380	COG1360	Flagellar Motor Protein
ETL58_RS15385	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ETL58_RS15390	COG1609	Transcriptional regulator
ETL58_RS15395	COG1605	Chorismate mutase
ETL58_RS15395	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ETL58_RS15400	COG3118	belongs to the thioredoxin family
ETL58_RS15405	COG4980	gas vesicle protein
ETL58_RS15410	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
ETL58_RS15415	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ETL58_RS15420	COG1674	ftsk spoiiie
ETL58_RS15425	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ETL58_RS15430	COG4848	Belongs to the UPF0354 family
ETL58_RS15435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETL58_RS15450	COG1363	Peptidase, m42
ETL58_RS15455	COG5584	Small secreted protein
ETL58_RS15460	COG0281	malic enzyme
ETL58_RS15465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETL58_RS15470	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ETL58_RS15480	COG0510	thiamine kinase activity
ETL58_RS15485	COG1523	belongs to the glycosyl hydrolase 13 family
ETL58_RS15490	COG1597	lipid kinase activity
ETL58_RS15500	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ETL58_RS15505	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ETL58_RS15510	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ETL58_RS15515	COG2252	PERMEase
ETL58_RS15520	COG4473	ABC transporter
ETL58_RS15525	COG1131	(ABC) transporter
ETL58_RS15530	COG1349	DNA-binding transcription factor activity
ETL58_RS15535	COG1187	pseudouridine synthase activity
ETL58_RS15540	COG2244	polysaccharide biosynthetic process
ETL58_RS15545	COG2081	HI0933 family
ETL58_RS15550	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ETL58_RS15560	COG5578	integral membrane protein
ETL58_RS15565	COG0673	inositol 2-dehydrogenase activity
ETL58_RS15570	COG1653	transport
ETL58_RS15575	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
ETL58_RS15580	COG4209	transmembrane transport
ETL58_RS15585	COG2207	Transcriptional regulator
ETL58_RS15590	COG1653	transport
ETL58_RS15595	COG0395	ABC-type sugar transport system, permease component
ETL58_RS15600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ETL58_RS15605	COG2124	cytochrome p450
ETL58_RS15610	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ETL58_RS15620	COG0156	8-amino-7-oxononanoate synthase activity
ETL58_RS15625	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ETL58_RS15635	COG1073	alpha beta
ETL58_RS15640	COG1609	Transcriptional regulator
ETL58_RS15645	COG1653	transport
ETL58_RS15650	COG1175	transmembrane transport
ETL58_RS15655	COG0395	ABC-type sugar transport system, permease component
ETL58_RS15660	COG1486	melibiose metabolic process
ETL58_RS15665	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ETL58_RS15670	COG0495	leucyl-tRNA aminoacylation
ETL58_RS15680	COG2202	Pas domain
ETL58_RS15680	COG1366	Belongs to the anti-sigma-factor antagonist family
ETL58_RS15685	COG2814	Major facilitator Superfamily
ETL58_RS15690	COG2433	Pfam Transposase IS66
ETL58_RS15695	COG0577	efflux transmembrane transporter activity
ETL58_RS15700	COG1136	(ABC) transporter
ETL58_RS15705	COG2205	protein histidine kinase activity
ETL58_RS15710	COG0745	RESPONSE REGULATOR receiver
ETL58_RS15715	COG0577	efflux transmembrane transporter activity
ETL58_RS15720	COG1136	(ABC) transporter
ETL58_RS15735	COG1131	(ABC) transporter
ETL58_RS15740	COG1725	Transcriptional regulator
ETL58_RS15755	COG1242	4 iron, 4 sulfur cluster binding
ETL58_RS15760	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
ETL58_RS15770	COG2267	carboxylic ester hydrolase activity
ETL58_RS15775	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ETL58_RS15780	COG1113	amino acid transport
ETL58_RS15785	COG0367	asparagine synthase
ETL58_RS15790	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ETL58_RS15795	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ETL58_RS15805	COG1506	peptidase
ETL58_RS15810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ETL58_RS15815	COG1116	anion transmembrane transporter activity
ETL58_RS15820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ETL58_RS15825	COG0494	nUDIX hydrolase
ETL58_RS15830	COG4824	toxin secretion phage lysis holin
ETL58_RS15835	COG0783	Belongs to the Dps family
ETL58_RS15850	COG1854	S-ribosylhomocysteine lyase activity
ETL58_RS15855	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ETL58_RS15860	COG0288	reversible hydration of carbon dioxide
ETL58_RS15865	COG0254	rRNA binding
ETL58_RS15870	COG1271	oxidase subunit
ETL58_RS15875	COG1294	oxidase, subunit
ETL58_RS15885	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ETL58_RS15890	COG1321	iron dependent repressor
ETL58_RS15890	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ETL58_RS15895	COG1121	(ABC) transporter
ETL58_RS15900	COG0803	Belongs to the bacterial solute-binding protein 9 family
ETL58_RS15905	COG4948	Mandelate Racemase Muconate Lactonizing
ETL58_RS15910	COG0318	PFAM AMP-dependent synthetase and ligase
ETL58_RS15915	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ETL58_RS15920	COG0596	Alpha beta hydrolase
ETL58_RS15925	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ETL58_RS15930	COG1169	isochorismate synthase
ETL58_RS15940	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ETL58_RS15945	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ETL58_RS15950	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ETL58_RS15955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ETL58_RS15960	COG0438	transferase activity, transferring glycosyl groups
ETL58_RS15970	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ETL58_RS15975	COG0438	transferase activity, transferring glycosyl groups
ETL58_RS15980	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ETL58_RS15985	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
ETL58_RS15990	COG0058	SHG alpha-glucan phosphorylase activity
ETL58_RS15995	COG0297	glycogen (starch) synthase activity
ETL58_RS16000	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ETL58_RS16005	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ETL58_RS16010	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ETL58_RS16135	COG3859	Proton-coupled thiamine transporter YuaJ
ETL58_RS16140	COG1247	-acetyltransferase
ETL58_RS16145	COG2268	Band 7 protein
ETL58_RS16150	COG1585	Membrane protein implicated in regulation of membrane protease activity
ETL58_RS16155	COG2318	DinB family
ETL58_RS16165	COG1454	alcohol dehydrogenase
ETL58_RS16170	COG1012	belongs to the aldehyde dehydrogenase family
ETL58_RS16175	COG1510	regulation of RNA biosynthetic process
ETL58_RS16185	COG0569	domain protein
ETL58_RS16190	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ETL58_RS16195	COG4682	membrane
ETL58_RS16200	COG1705	Flagellar rod assembly protein muramidase FlgJ
ETL58_RS16205	COG0477	Major facilitator Superfamily
ETL58_RS16210	COG5553	Cysteine dioxygenase type I
ETL58_RS16220	COG1968	undecaprenyl-diphosphatase activity
ETL58_RS16225	COG0628	permease
ETL58_RS16230	COG0673	inositol 2-dehydrogenase activity
ETL58_RS16235	COG4806	L-rhamnose isomerase
ETL58_RS16240	COG3254	rhamnose metabolic process
ETL58_RS16245	COG1070	Carbohydrate kinase
ETL58_RS16250	COG1349	DNA-binding transcription factor activity
ETL58_RS16255	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_RS16255	COG3347	Dehydrogenase
ETL58_RS16265	COG0840	transmembrane signaling receptor activity
ETL58_RS16270	COG0840	transmembrane signaling receptor activity
ETL58_RS16275	COG0840	transmembrane signaling receptor activity
ETL58_RS16295	COG0432	Pfam Uncharacterised protein family UPF0047
ETL58_RS16305	COG0366	Alpha amylase catalytic
ETL58_RS16310	COG1253	flavin adenine dinucleotide binding
ETL58_RS16315	COG2738	Putative neutral zinc metallopeptidase
ETL58_RS16330	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ETL58_RS16345	COG0166	Belongs to the GPI family
ETL58_RS16350	COG1979	alcohol dehydrogenase
ETL58_RS16355	COG1979	alcohol dehydrogenase
ETL58_RS16360	COG2155	Conserved Protein
ETL58_RS16365	COG1098	S1 RNA binding domain
ETL58_RS16370	COG0436	Aminotransferase
ETL58_RS16375	COG1522	sequence-specific DNA binding
ETL58_RS16380	COG2267	carboxylic ester hydrolase activity
ETL58_RS16390	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ETL58_RS16395	COG2205	protein histidine kinase activity
ETL58_RS16405	COG5018	Exonuclease
ETL58_RS16415	COG2814	Major facilitator Superfamily
ETL58_RS16420	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ETL58_RS16425	COG3011	Protein conserved in bacteria
ETL58_RS16435	COG3290	protein histidine kinase activity
ETL58_RS16440	COG4565	transcriptional regulatory protein
ETL58_RS16445	COG1744	ABC transporter substrate-binding protein PnrA-like
ETL58_RS16450	COG3845	ABC transporter
ETL58_RS16455	COG4603	Belongs to the binding-protein-dependent transport system permease family
ETL58_RS16460	COG1079	Belongs to the binding-protein-dependent transport system permease family
ETL58_RS16465	COG3493	citrate carrier protein
ETL58_RS16475	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ETL58_RS16475	COG2111	Na H antiporter
ETL58_RS16480	COG2111	Na H antiporter
ETL58_RS16485	COG1006	Multisubunit Na H antiporter MnhC subunit
ETL58_RS16490	COG0651	ATP synthesis coupled electron transport
ETL58_RS16495	COG1863	multisubunit Na H antiporter MnhE subunit
ETL58_RS16500	COG2212	antiporter activity
ETL58_RS16505	COG1320	monovalent cation:proton antiporter activity
ETL58_RS16510	COG2050	protein possibly involved in aromatic compounds catabolism
ETL58_RS16515	COG2197	response regulator
ETL58_RS16520	COG4585	Histidine kinase
ETL58_RS16530	COG0142	geranyltranstransferase activity
ETL58_RS16550	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ETL58_RS16555	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ETL58_RS16560	COG1335	isochorismatase
ETL58_RS16565	COG5506	Protein of unknown function (DUF1694)
ETL58_RS16580	COG0628	permease
ETL58_RS16595	COG1418	mRNA catabolic process
ETL58_RS16600	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_RS16610	COG1511	domain protein
ETL58_RS16615	COG0433	COG0433 Predicted ATPase
ETL58_RS16615	COG1674	ftsk spoiiie
ETL58_RS16620	COG4499	WXG100 protein secretion system (Wss), protein YukC
ETL58_RS16625	COG5417	Belongs to the EsaB family
ETL58_RS16630	COG4842	Belongs to the WXG100 family
ETL58_RS16640	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
ETL58_RS16640	COG2508	Transcriptional regulator
ETL58_RS16645	COG0686	Belongs to the AlaDH PNT family
ETL58_RS16650	COG5634	Uncharacterized conserved protein (DUF2278)
ETL58_RS16655	COG3251	PFAM MbtH domain protein
ETL58_RS16660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETL58_RS16665	COG3433	isochorismatase activity
ETL58_RS16665	COG1535	isochorismatase
ETL58_RS16670	COG1021	2,3-dihydroxybenzoate-AMP ligase
ETL58_RS16675	COG1169	isochorismate synthase
ETL58_RS16680	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_RS16685	COG2819	hydrolase of the alpha beta superfamily
ETL58_RS16690	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ETL58_RS16695	COG1268	BioY protein
ETL58_RS16700	COG2056	Na+-H+ antiporter family
ETL58_RS16705	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ETL58_RS16710	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
ETL58_RS16715	COG3584	3D domain protein
ETL58_RS16730	COG1252	NADH dehydrogenase
ETL58_RS16735	COG0492	ferredoxin-NADP+ reductase activity
ETL58_RS16745	COG0516	GMP reductase activity
ETL58_RS16750	COG2808	Putative FMN-binding domain
ETL58_RS16755	COG0456	acetyltransferase
ETL58_RS16760	COG0316	Belongs to the HesB IscA family
ETL58_RS16765	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ETL58_RS16770	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ETL58_RS16775	COG4844	belongs to the
ETL58_RS16780	COG1252	NADH dehydrogenase
ETL58_RS16785	COG4837	Protein of unknown function (DUF1462)
ETL58_RS16790	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ETL58_RS16795	COG1506	peptidase
ETL58_RS16795	COG0823	Involved in the tonB-independent uptake of proteins
ETL58_RS16795	COG4946	Tricorn protease homolog
ETL58_RS16800	COG0083	homoserine kinase activity
ETL58_RS16805	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ETL58_RS16810	COG0460	homoserine dehydrogenase
ETL58_RS16820	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ETL58_RS16825	COG0647	UMP catabolic process
ETL58_RS16830	COG2445	Protein of unknown function DUF86
ETL58_RS16835	COG4470	Protein conserved in bacteria
ETL58_RS16845	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ETL58_RS16850	COG0739	heme binding
ETL58_RS16860	COG3377	Domain of unknown function (DUF1805)
ETL58_RS16865	COG0737	Belongs to the 5'-nucleotidase family
ETL58_RS16870	COG0730	response to heat
ETL58_RS16875	COG1801	Protein of unknown function DUF72
ETL58_RS16885	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ETL58_RS16890	COG2508	Transcriptional regulator
ETL58_RS16895	COG2233	PERMEase
ETL58_RS16900	COG2233	PERMEase
ETL58_RS16905	COG3648	Uricase
ETL58_RS16905	COG3195	allantoin biosynthetic process
ETL58_RS16910	COG2351	hydroxyisourate hydrolase activity
ETL58_RS16920	COG2080	2 iron, 2 sulfur cluster binding
ETL58_RS16925	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ETL58_RS16930	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ETL58_RS16935	COG2068	MobA-Related Protein
ETL58_RS16940	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ETL58_RS16945	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ETL58_RS16950	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ETL58_RS16960	COG2356	endonuclease I
ETL58_RS16965	COG3842	ATPase activity
ETL58_RS16970	COG2188	Transcriptional regulator
ETL58_RS16975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ETL58_RS16980	COG0395	ABC-type sugar transport system, permease component
ETL58_RS16985	COG1175	transmembrane transport
ETL58_RS16990	COG1653	transport
ETL58_RS16995	COG2222	sugar isomerase
ETL58_RS17000	COG0322	excinuclease ABC activity
ETL58_RS17005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ETL58_RS17020	COG0346	lactoylglutathione lyase activity
ETL58_RS17025	COG0640	Transcriptional regulator
ETL58_RS17030	COG0719	Fe-S assembly protein
ETL58_RS17035	COG0822	iron-sulfur transferase activity
ETL58_RS17040	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ETL58_RS17045	COG0719	Fe-S assembly protein
ETL58_RS17050	COG0396	ATPase activity
ETL58_RS17065	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ETL58_RS17070	COG1464	Belongs to the NlpA lipoprotein family
ETL58_RS17075	COG2011	ABC-type metal ion transport system permease component
ETL58_RS17080	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ETL58_RS17090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETL58_RS17095	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ETL58_RS17105	COG0509	glycine decarboxylation via glycine cleavage system
ETL58_RS17110	COG1393	Belongs to the ArsC family
ETL58_RS17115	COG1960	acyl-CoA dehydrogenase activity
ETL58_RS17120	COG0183	Belongs to the thiolase family
ETL58_RS17125	COG1024	Enoyl-CoA hydratase
ETL58_RS17125	COG1250	3-hydroxyacyl-CoA dehydrogenase
ETL58_RS17135	COG0506	proline dehydrogenase activity
ETL58_RS17145	COG5577	PFAM Coat F domain
ETL58_RS17150	COG1846	Transcriptional regulator
ETL58_RS17155	COG0477	Major facilitator Superfamily
ETL58_RS17160	COG1942	4-Oxalocrotonate Tautomerase
ETL58_RS17165	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_RS17170	COG0583	DNA-binding transcription factor activity
ETL58_RS17180	COG1120	ATPase activity
ETL58_RS17195	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_RS17200	COG0783	Belongs to the Dps family
ETL58_RS17205	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETL58_RS17210	COG0745	RESPONSE REGULATOR receiver
ETL58_RS17215	COG2205	protein histidine kinase activity
ETL58_RS17215	COG2770	Histidine kinase
ETL58_RS17225	COG1309	transcriptional regulator
ETL58_RS17230	COG0114	fumarate hydratase activity
ETL58_RS17240	COG0697	spore germination
ETL58_RS17245	COG0814	amino acid
ETL58_RS17255	COG2197	response regulator
ETL58_RS17260	COG4585	Histidine kinase
ETL58_RS17265	COG4758	membrane
ETL58_RS17270	COG3595	metallopeptidase activity
ETL58_RS17275	COG1842	Phage shock protein A
ETL58_RS17280	COG4758	membrane
ETL58_RS17285	COG2814	Major facilitator Superfamily
ETL58_RS17290	COG2096	Adenosyltransferase
ETL58_RS17295	COG1120	ATPase activity
ETL58_RS17300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETL58_RS17305	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ETL58_RS17310	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_RS17315	COG3386	PFAM SMP-30 Gluconolaconase
ETL58_RS17320	COG2205	protein histidine kinase activity
ETL58_RS17325	COG0745	RESPONSE REGULATOR receiver
ETL58_RS17335	COG1191	sigma factor activity
ETL58_RS17345	COG2140	Oxalate decarboxylase
ETL58_RS17355	COG0577	efflux transmembrane transporter activity
ETL58_RS17360	COG1136	(ABC) transporter
ETL58_RS17365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ETL58_RS17370	COG1120	ATPase activity
ETL58_RS17375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETL58_RS17380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETL58_RS17385	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ETL58_RS17395	COG0531	amino acid
ETL58_RS17410	COG1988	membrane-bound metal-dependent
ETL58_RS17415	COG1368	sulfuric ester hydrolase activity
ETL58_RS17420	COG1910	domain protein
ETL58_RS17425	COG0725	ABC transporter, periplasmic molybdate-binding protein
ETL58_RS17430	COG4149	molybdate abc transporter
ETL58_RS17435	COG0656	L-ascorbic acid biosynthetic process
ETL58_RS17445	COG0025	NhaP-type Na H and K H
ETL58_RS17450	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ETL58_RS17455	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ETL58_RS17460	COG3973	AAA domain
ETL58_RS17465	COG2860	membrane
ETL58_RS17470	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ETL58_RS17475	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ETL58_RS17480	COG2217	Heavy metal translocating P-type atpase
ETL58_RS17485	COG2217	Heavy metal translocating P-type atpase
ETL58_RS17490	COG2608	mercury ion transmembrane transporter activity
ETL58_RS17495	COG1937	Protein conserved in bacteria
ETL58_RS17500	COG0673	inositol 2-dehydrogenase activity
ETL58_RS17505	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ETL58_RS17510	COG1289	transmembrane transporter activity
ETL58_RS17520	COG2076	Multidrug Resistance protein
ETL58_RS17525	COG1309	transcriptional regulator
ETL58_RS17530	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_RS17540	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ETL58_RS17545	COG0557	exoribonuclease II activity
ETL58_RS17550	COG1647	Serine aminopeptidase, S33
ETL58_RS17555	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ETL58_RS17560	COG0596	Alpha beta hydrolase
ETL58_RS17565	COG1476	TRANSCRIPTIONal
ETL58_RS17570	COG1396	sequence-specific DNA binding
ETL58_RS17575	COG1396	sequence-specific DNA binding
ETL58_RS17580	COG1733	regulation of RNA biosynthetic process
ETL58_RS17585	COG0840	transmembrane signaling receptor activity
ETL58_RS17590	COG1174	glycine betaine transport
ETL58_RS17595	COG1732	Glycine betaine
ETL58_RS17600	COG1174	glycine betaine transport
ETL58_RS17605	COG0517	IMP dehydrogenase activity
ETL58_RS17605	COG1125	glycine betaine transport
ETL58_RS17610	COG1510	regulation of RNA biosynthetic process
ETL58_RS17615	COG1174	glycine betaine transport
ETL58_RS17620	COG1732	Glycine betaine
ETL58_RS17625	COG1174	glycine betaine transport
ETL58_RS17630	COG0517	IMP dehydrogenase activity
ETL58_RS17630	COG1125	glycine betaine transport
ETL58_RS17635	COG1510	regulation of RNA biosynthetic process
ETL58_RS17640	COG2095	MarC family integral membrane protein
ETL58_RS17650	COG3064	Membrane
ETL58_RS17655	COG4640	response to antibiotic
ETL58_RS17660	COG0456	acetyltransferase
ETL58_RS17665	COG0148	phosphopyruvate hydratase activity
ETL58_RS17670	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ETL58_RS17675	COG0149	triose-phosphate isomerase activity
ETL58_RS17680	COG0126	phosphoglycerate kinase activity
ETL58_RS17685	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ETL58_RS17690	COG2390	Transcriptional regulator
ETL58_RS17695	COG2814	Major facilitator Superfamily
ETL58_RS17700	COG1609	Transcriptional regulator
ETL58_RS17705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ETL58_RS17715	COG0583	DNA-binding transcription factor activity
ETL58_RS17720	COG0697	spore germination
ETL58_RS17725	COG1113	amino acid transport
ETL58_RS17730	COG3858	chitin binding
ETL58_RS17735	COG1556	Lactate utilization protein
ETL58_RS17740	COG1139	Iron-sulfur cluster binding protein
ETL58_RS17745	COG0247	lactate metabolic process
ETL58_RS17750	COG2197	response regulator
ETL58_RS17755	COG4585	Histidine kinase
ETL58_RS17760	COG0842	Transport permease protein
ETL58_RS17765	COG1131	(ABC) transporter
ETL58_RS17770	COG0596	Alpha beta hydrolase
ETL58_RS17775	COG2208	phosphoserine phosphatase activity
ETL58_RS17780	COG3867	Arabinogalactan endo-beta-1,4-galactanase
ETL58_RS17785	COG1874	Beta-galactosidase
ETL58_RS17790	COG3833	ABC-type maltose transport systems, permease component
ETL58_RS17795	COG1175	transmembrane transport
ETL58_RS17800	COG2182	Extracellular solute-binding protein
ETL58_RS17805	COG1609	Transcriptional regulator
ETL58_RS17810	COG2186	Transcriptional regulator
ETL58_RS17815	COG1620	l-lactate permease
ETL58_RS17820	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ETL58_RS17830	COG5039	Polysaccharide pyruvyl transferase
ETL58_RS17835	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ETL58_RS17840	COG0110	maltose O-acetyltransferase activity
ETL58_RS17845	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ETL58_RS17850	COG2244	polysaccharide biosynthetic process
ETL58_RS17855	COG1216	Glycosyl transferase, family 2
ETL58_RS17860	COG5039	Polysaccharide pyruvyl transferase
ETL58_RS17865	COG1216	Glycosyl transferase, family 2
ETL58_RS17875	COG0438	transferase activity, transferring glycosyl groups
ETL58_RS17880	COG1215	transferase activity, transferring glycosyl groups
ETL58_RS17885	COG0438	transferase activity, transferring glycosyl groups
ETL58_RS17890	COG1086	Polysaccharide biosynthesis protein
ETL58_RS17895	COG0489	protein tyrosine kinase activity
ETL58_RS17900	COG3944	biosynthesis protein
ETL58_RS17905	COG1396	sequence-specific DNA binding
ETL58_RS17910	COG2272	Belongs to the type-B carboxylesterase lipase family
ETL58_RS17920	COG3479	Phenolic acid decarboxylase
ETL58_RS17930	COG1794	racemase activity, acting on amino acids and derivatives
ETL58_RS17935	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ETL58_RS17940	COG1621	beta-fructofuranosidase activity
ETL58_RS17945	COG1621	beta-fructofuranosidase activity
ETL58_RS17950	COG0531	amino acid
ETL58_RS17955	COG1309	transcriptional regulator
ETL58_RS17960	COG2076	Multidrug Resistance protein
ETL58_RS17965	COG2076	Multidrug Resistance protein
ETL58_RS17975	COG0277	FAD linked oxidase domain protein
ETL58_RS17980	COG3621	Patatin-like phospholipase
ETL58_RS17990	COG0740	serine-type endopeptidase activity
ETL58_RS17995	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ETL58_RS18000	COG0366	Alpha amylase catalytic
ETL58_RS18005	COG1554	hydrolase, family 65, central catalytic
ETL58_RS18010	COG5521	maltodextrose utilization protein MalA
ETL58_RS18015	COG3833	ABC-type maltose transport systems, permease component
ETL58_RS18020	COG1175	transmembrane transport
ETL58_RS18025	COG2182	Extracellular solute-binding protein
ETL58_RS18035	COG1609	Transcriptional regulator
ETL58_RS18040	COG1611	Belongs to the LOG family
ETL58_RS18045	COG1694	Mazg nucleotide pyrophosphohydrolase
ETL58_RS18050	COG0659	secondary active sulfate transmembrane transporter activity
ETL58_RS18055	COG0288	reversible hydration of carbon dioxide
ETL58_RS18065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ETL58_RS18070	COG0577	efflux transmembrane transporter activity
ETL58_RS18075	COG1136	(ABC) transporter
ETL58_RS18080	COG5002	protein histidine kinase activity
ETL58_RS18085	COG0745	RESPONSE REGULATOR receiver
ETL58_RS18095	COG2162	N-hydroxyarylamine O-acetyltransferase activity
ETL58_RS18100	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETL58_RS18105	COG1481	regulation of sporulation
ETL58_RS18110	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ETL58_RS18115	COG1660	Displays ATPase and GTPase activities
ETL58_RS18120	COG1051	belongs to the nudix hydrolase family
ETL58_RS18125	COG0492	ferredoxin-NADP+ reductase activity
ETL58_RS18130	COG0791	NLP P60 protein
ETL58_RS18130	COG3883	PFAM NLP P60 protein
ETL58_RS18135	COG0457	Tetratricopeptide repeat
ETL58_RS18140	COG1132	(ABC) transporter
ETL58_RS18165	COG0140	phosphoribosyl-ATP diphosphatase activity
ETL58_RS18165	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ETL58_RS18170	COG0107	imidazoleglycerol-phosphate synthase activity
ETL58_RS18175	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ETL58_RS18180	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ETL58_RS18185	COG0131	Imidazoleglycerol-phosphate dehydratase
ETL58_RS18190	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ETL58_RS18195	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ETL58_RS18200	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ETL58_RS18205	COG4990	cell redox homeostasis
ETL58_RS18210	COG5297	Belongs to the glycosyl hydrolase family 6
ETL58_RS18215	COG0110	maltose O-acetyltransferase activity
ETL58_RS18220	COG0546	phosphoglycolate phosphatase activity
ETL58_RS18225	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ETL58_RS18230	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ETL58_RS18235	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ETL58_RS18240	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ETL58_RS18245	COG0363	glucosamine-6-phosphate deaminase activity
ETL58_RS18250	COG2188	Transcriptional regulator
ETL58_RS18255	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ETL58_RS18260	COG1846	Transcriptional regulator
ETL58_RS18265	COG2124	cytochrome p450
ETL58_RS18275	COG1846	Transcriptional regulator
ETL58_RS18280	COG2814	Major facilitator Superfamily
ETL58_RS18285	COG1950	PFAM Membrane protein of
ETL58_RS18290	COG1983	PspC domain protein
ETL58_RS18295	COG3595	metallopeptidase activity
ETL58_RS18310	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ETL58_RS18315	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ETL58_RS18325	COG4897	Protein conserved in bacteria
ETL58_RS18330	COG3848	Pyruvate phosphate dikinase
ETL58_RS18330	COG0574	Belongs to the PEP-utilizing enzyme family
ETL58_RS18335	COG1309	transcriptional regulator
ETL58_RS18340	COG2814	Major facilitator Superfamily
ETL58_RS18345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETL58_RS18355	COG0793	Belongs to the peptidase S41A family
ETL58_RS18355	COG3409	Peptidoglycan-binding domain 1 protein
ETL58_RS18360	COG2177	Part of the ABC transporter FtsEX involved in
ETL58_RS18365	COG2884	Cell division ATP-binding protein ftsE
ETL58_RS18370	COG2010	Cytochrome c
ETL58_RS18375	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETL58_RS18385	COG0653	protein targeting
ETL58_RS18390	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ETL58_RS18405	COG1516	flagellar protein fliS
ETL58_RS18410	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ETL58_RS18415	COG1334	flagellar protein FlaG
ETL58_RS18420	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ETL58_RS18425	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ETL58_RS18430	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
ETL58_RS18440	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ETL58_RS18445	COG4786	Flagellar basal body rod
ETL58_RS18445	COG1256	bacterial-type flagellum assembly
ETL58_RS18450	COG3418	PFAM FlgN family protein
ETL58_RS18455	COG2747	anti-sigma28 factor FlgM
ETL58_RS18465	COG1040	competence protein
ETL58_RS18475	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
ETL58_RS18480	COG1307	EDD domain protein, DegV family
ETL58_RS18485	COG2197	response regulator
ETL58_RS18490	COG4585	Histidine kinase
ETL58_RS18495	COG1739	Uncharacterized protein family UPF0029
ETL58_RS18500	COG1316	TRANSCRIPTIONal
ETL58_RS18505	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ETL58_RS18510	COG0438	transferase activity, transferring glycosyl groups
ETL58_RS18515	COG1215	transferase activity, transferring glycosyl groups
ETL58_RS18520	COG3206	protein involved in exopolysaccharide biosynthesis
ETL58_RS18525	COG3307	-O-antigen
ETL58_RS18530	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ETL58_RS18535	COG0297	glycogen (starch) synthase activity
ETL58_RS18535	COG0438	transferase activity, transferring glycosyl groups
ETL58_RS18540	COG2244	polysaccharide biosynthetic process
ETL58_RS18555	COG2247	cell wall binding repeat
ETL58_RS18555	COG0860	N-Acetylmuramoyl-L-alanine amidase
ETL58_RS18560	COG2247	cell wall binding repeat
ETL58_RS18560	COG2385	sporulation resulting in formation of a cellular spore
ETL58_RS18570	COG1316	TRANSCRIPTIONal
ETL58_RS18575	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ETL58_RS18595	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ETL58_RS18600	COG1134	teichoic acid transport
ETL58_RS18605	COG1682	transport, permease protein
ETL58_RS18625	COG0463	Glycosyl transferase, family 2
ETL58_RS18670	COG4193	domain, Protein
ETL58_RS18675	COG1482	cell wall glycoprotein biosynthetic process
ETL58_RS18680	COG0697	spore germination
ETL58_RS18685	COG0814	amino acid
ETL58_RS18695	COG2814	Major facilitator Superfamily
ETL58_RS18700	COG1316	TRANSCRIPTIONal
ETL58_RS18705	COG0561	phosphatase activity
ETL58_RS18710	COG0791	NLP P60 protein
ETL58_RS18720	COG2843	Capsule synthesis protein
ETL58_RS18730	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ETL58_RS18740	COG1609	Transcriptional regulator
ETL58_RS18745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ETL58_RS18750	COG1869	D-ribose catabolic process
ETL58_RS18755	COG1129	ABC transporter
ETL58_RS18760	COG1172	Belongs to the binding-protein-dependent transport system permease family
ETL58_RS18765	COG1879	ABC-type sugar transport system periplasmic component
ETL58_RS18770	COG3103	Sh3 type 3 domain protein
ETL58_RS18780	COG2249	NAD(P)H dehydrogenase (quinone) activity
ETL58_RS18785	COG3527	Alpha-acetolactate decarboxylase
ETL58_RS18790	COG0028	Belongs to the TPP enzyme family
ETL58_RS18795	COG0583	DNA-binding transcription factor activity
ETL58_RS18800	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ETL58_RS18815	COG5337	Spore coat protein CotH
ETL58_RS18825	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ETL58_RS18835	COG0405	Gamma-glutamyltransferase
ETL58_RS18840	COG1522	sequence-specific DNA binding
ETL58_RS18845	COG2059	Chromate
ETL58_RS18850	COG2059	Chromate
ETL58_RS18860	COG0655	NAD(P)H dehydrogenase (quinone) activity
ETL58_RS18865	COG0583	DNA-binding transcription factor activity
ETL58_RS18880	COG5444	nuclease activity
ETL58_RS18900	COG3878	Protein conserved in bacteria
ETL58_RS18905	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ETL58_RS18910	COG4464	protein tyrosine phosphatase activity
ETL58_RS18915	COG0489	protein tyrosine kinase activity
ETL58_RS18920	COG3944	biosynthesis protein
ETL58_RS18930	COG4715	Zinc finger, swim domain protein
ETL58_RS18935	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ETL58_RS18945	COG0561	phosphatase activity
ETL58_RS18950	COG1349	DNA-binding transcription factor activity
ETL58_RS18955	COG0629	single-stranded DNA binding
ETL58_RS18970	COG3764	Sortase (surface protein transpeptidase)
ETL58_RS18975	COG2972	Histidine kinase
ETL58_RS18975	COG0745	RESPONSE REGULATOR receiver
ETL58_RS18980	COG1970	mechanosensitive ion channel activity
ETL58_RS18985	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ETL58_RS18990	COG0457	Tetratricopeptide repeat
ETL58_RS18995	COG4786	Flagellar basal body rod
ETL58_RS19000	COG4786	Flagellar basal body rod
ETL58_RS19005	COG1077	Cell shape determining protein MreB Mrl
ETL58_RS19010	COG1609	Transcriptional regulator
ETL58_RS19020	COG1846	Transcriptional regulator
ETL58_RS19025	COG2814	Major facilitator Superfamily
ETL58_RS19030	COG3420	alginic acid biosynthetic process
ETL58_RS19035	COG1953	Uracil, thiamine, allantoin
ETL58_RS19040	COG0477	Major facilitator Superfamily
ETL58_RS19045	COG1335	isochorismatase
ETL58_RS19055	COG0004	ammonium transporteR
ETL58_RS19060	COG0347	Belongs to the P(II) protein family
ETL58_RS19065	COG0671	phosphoesterase, PA-phosphatase related
ETL58_RS19075	COG0739	heme binding
ETL58_RS19080	COG1247	-acetyltransferase
ETL58_RS19100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ETL58_RS19105	COG0789	Transcriptional regulator
ETL58_RS19115	COG2910	NAD(P)H-binding
ETL58_RS19120	COG1959	2 iron, 2 sulfur cluster binding
ETL58_RS19125	COG0804	urea catabolic process
ETL58_RS19130	COG0832	Belongs to the urease beta subunit family
ETL58_RS19135	COG0831	urea catabolic process
ETL58_RS19150	COG3237	CsbD-like
ETL58_RS19155	COG1994	Peptidase M50
ETL58_RS19160	COG0457	Tetratricopeptide repeat
ETL58_RS19165	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ETL58_RS19170	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ETL58_RS19180	COG2304	oxidoreductase activity
ETL58_RS19190	COG2304	oxidoreductase activity
ETL58_RS19195	COG2385	sporulation resulting in formation of a cellular spore
ETL58_RS19200	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ETL58_RS19210	COG4836	Membrane
ETL58_RS19220	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ETL58_RS19225	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ETL58_RS19230	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ETL58_RS19235	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ETL58_RS19240	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ETL58_RS19245	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ETL58_RS19255	COG0356	it plays a direct role in the translocation of protons across the membrane
ETL58_RS19265	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ETL58_RS19270	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ETL58_RS19275	COG4475	Protein of unknown function (DUF436)
ETL58_RS19280	COG0698	ribose 5-phosphate isomerase
ETL58_RS19285	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ETL58_RS19290	COG1971	Probably functions as a manganese efflux pump
ETL58_RS19295	COG0009	L-threonylcarbamoyladenylate synthase
ETL58_RS19300	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ETL58_RS19320	COG2890	protein-(glutamine-N5) methyltransferase activity
ETL58_RS19325	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ETL58_RS19330	COG0346	lactoylglutathione lyase activity
ETL58_RS19335	COG0789	Transcriptional regulator
ETL58_RS19340	COG0679	Auxin Efflux Carrier
ETL58_RS19345	COG0281	malic enzyme
ETL58_RS19350	COG1435	thymidine kinase activity
ETL58_RS19360	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ETL58_RS19370	COG1494	fructose-1,6-bisphosphatase
ETL58_RS19375	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ETL58_RS19380	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ETL58_RS19385	COG0191	fructose-bisphosphate aldolase activity
ETL58_RS19390	COG2204	response regulator
ETL58_RS19395	COG4821	SIS domain
ETL58_RS19400	COG0504	CTP synthase activity
ETL58_RS19405	COG3343	RNA polymerase activity
ETL58_RS19410	COG1960	acyl-CoA dehydrogenase activity
ETL58_RS19415	COG0247	lactate metabolic process
ETL58_RS19415	COG2181	nitrate reductase activity
ETL58_RS19420	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ETL58_RS19425	COG4294	response to UV
ETL58_RS19435	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ETL58_RS19440	COG1132	(ABC) transporter
ETL58_RS19445	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ETL58_RS19455	COG2181	nitrate reductase activity
ETL58_RS19460	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
ETL58_RS19465	COG1140	nitrate reductase beta subunit
ETL58_RS19470	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ETL58_RS19475	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ETL58_RS19485	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ETL58_RS19490	COG2223	nitrite transmembrane transporter activity
ETL58_RS19495	COG0018	arginyl-trna synthetase
ETL58_RS19500	COG4506	Protein conserved in bacteria
ETL58_RS19515	COG0535	radical SAM domain protein
ETL58_RS19525	COG1131	(ABC) transporter
ETL58_RS19530	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ETL58_RS19535	COG0612	Peptidase, M16
ETL58_RS19540	COG0612	Peptidase, M16
ETL58_RS19550	COG3391	amine dehydrogenase activity
ETL58_RS19555	COG3391	amine dehydrogenase activity
ETL58_RS19565	COG0457	Tetratricopeptide repeat
ETL58_RS19595	COG1131	(ABC) transporter
ETL58_RS19605	COG0010	Belongs to the arginase family
ETL58_RS19610	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ETL58_RS19615	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ETL58_RS19630	COG1994	Peptidase M50
ETL58_RS19635	COG1942	4-Oxalocrotonate Tautomerase
ETL58_RS19640	COG1846	Transcriptional regulator
ETL58_RS19645	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ETL58_RS19655	COG0477	Major facilitator Superfamily
ETL58_RS19660	COG1959	2 iron, 2 sulfur cluster binding
ETL58_RS19665	COG3465	dGTPase activity
ETL58_RS19670	COG1078	dGTPase activity
ETL58_RS19675	COG4844	belongs to the
ETL58_RS19685	COG0697	spore germination
ETL58_RS19690	COG0095	Lipoate-protein ligase
ETL58_RS19695	COG0583	DNA-binding transcription factor activity
ETL58_RS19700	COG0280	phosphate acetyltransferase
ETL58_RS19705	COG3253	May function as heme-dependent peroxidase
ETL58_RS19710	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_RS19715	COG0436	Aminotransferase
ETL58_RS19720	COG2814	Major facilitator Superfamily
ETL58_RS19725	COG0151	Belongs to the GarS family
ETL58_RS19730	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_RS19735	COG1917	Cupin 2, conserved barrel domain protein
ETL58_RS19740	COG0077	Prephenate dehydratase
ETL58_RS19745	COG2814	Major facilitator Superfamily
ETL58_RS19750	COG0833	amino acid
ETL58_RS19755	COG4187	Peptidase family M20/M25/M40
ETL58_RS19760	COG1012	belongs to the aldehyde dehydrogenase family
ETL58_RS19765	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ETL58_RS19775	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
ETL58_RS19780	COG1091	dTDP-4-dehydrorhamnose reductase activity
ETL58_RS19785	COG1088	dTDP-glucose 4,6-dehydratase activity
ETL58_RS19790	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ETL58_RS19795	COG3980	spore coat polysaccharide biosynthesis protein
ETL58_RS19800	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
ETL58_RS19805	COG2089	acid synthase
ETL58_RS19810	COG0456	acetyltransferase
ETL58_RS19815	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ETL58_RS19820	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ETL58_RS19825	COG0463	Glycosyl transferase, family 2
ETL58_RS19840	COG2363	Small membrane protein
ETL58_RS19845	COG2233	PERMEase
ETL58_RS19855	COG1012	belongs to the aldehyde dehydrogenase family
ETL58_RS19860	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ETL58_RS19865	COG1216	Glycosyl transferase, family 2
ETL58_RS19880	COG1695	Transcriptional regulator
ETL58_RS19885	COG0351	phosphomethylpyrimidine kinase
ETL58_RS19895	COG1621	beta-fructofuranosidase activity
ETL58_RS19900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETL58_RS19900	COG1263	PTS System
ETL58_RS19905	COG2116	formate transmembrane transporter activity
ETL58_RS19910	COG3711	transcriptional antiterminator
ETL58_RS19920	COG1404	Belongs to the peptidase S8 family
ETL58_RS19925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ETL58_RS19930	COG0778	Nitroreductase
ETL58_RS19935	COG0772	Belongs to the SEDS family
ETL58_RS19945	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ETL58_RS19950	COG1845	cytochrome c oxidase, subunit III
ETL58_RS19955	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ETL58_RS19960	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ETL58_RS19965	COG2261	transglycosylase associated protein
ETL58_RS19970	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
ETL58_RS19975	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ETL58_RS19980	COG2246	polysaccharide biosynthetic process
ETL58_RS19985	COG1309	transcriptional regulator
ETL58_RS19995	COG3162	membrane
ETL58_RS20000	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ETL58_RS20005	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ETL58_RS20010	COG2837	iron assimilation
ETL58_RS20015	COG2822	iron ion transport
ETL58_RS20020	COG0672	)-iron permease
ETL58_RS20025	COG0352	thiamine-phosphate diphosphorylase activity
ETL58_RS20030	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ETL58_RS20035	COG0583	DNA-binding transcription factor activity
ETL58_RS20040	COG1380	Effector of murein hydrolase LrgA
ETL58_RS20045	COG1346	cytolysis
ETL58_RS20050	COG2814	Major facilitator Superfamily
ETL58_RS20055	COG4895	conserved protein (DUF2196)
ETL58_RS20060	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ETL58_RS20065	COG0346	lactoylglutathione lyase activity
ETL58_RS20070	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETL58_RS20075	COG1404	Belongs to the peptidase S8 family
ETL58_RS20080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETL58_RS20080	COG1263	PTS System
ETL58_RS20085	COG3711	transcriptional antiterminator
ETL58_RS20090	COG1442	glycosyl transferase family 8
ETL58_RS20095	COG5522	Integral membrane protein (intg_mem_TP0381)
ETL58_RS20100	COG1846	Transcriptional regulator
ETL58_RS20105	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ETL58_RS20110	COG2234	aminopeptidase activity
ETL58_RS20125	COG2814	Major facilitator Superfamily
ETL58_RS20130	COG2357	RelA SpoT domain protein
ETL58_RS20135	COG1575	Belongs to the MenA family. Type 1 subfamily
ETL58_RS20155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETL58_RS20160	COG1696	Membrane protein involved in D-alanine export
ETL58_RS20165	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETL58_RS20170	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
ETL58_RS20175	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
ETL58_RS20180	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ETL58_RS20185	COG1486	melibiose metabolic process
ETL58_RS20190	COG1447	Phosphotransferase system cellobiose-specific component IIA
ETL58_RS20195	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETL58_RS20200	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETL58_RS20205	COG3711	transcriptional antiterminator
ETL58_RS20205	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETL58_RS20215	COG2094	Belongs to the DNA glycosylase MPG family
ETL58_RS20220	COG0753	catalase activity
ETL58_RS20225	COG2814	Major facilitator Superfamily
ETL58_RS20230	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
ETL58_RS20235	COG1131	(ABC) transporter
ETL58_RS20255	COG1595	DNA-templated transcription, initiation
ETL58_RS20260	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ETL58_RS20265	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ETL58_RS20270	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ETL58_RS20275	COG4988	ABC transporter
ETL58_RS20280	COG1294	oxidase, subunit
ETL58_RS20285	COG1271	oxidase subunit
ETL58_RS20290	COG3493	citrate carrier protein
ETL58_RS20295	COG0501	Belongs to the peptidase M48B family
ETL58_RS20305	COG0726	polysaccharide deacetylase
ETL58_RS20310	COG3842	ATPase activity
ETL58_RS20315	COG2508	Transcriptional regulator
ETL58_RS20320	COG1012	belongs to the aldehyde dehydrogenase family
ETL58_RS20325	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETL58_RS20335	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ETL58_RS20340	COG1881	PFAM PEBP family protein
ETL58_RS20345	COG0583	DNA-binding transcription factor activity
ETL58_RS20355	COG4585	Histidine kinase
ETL58_RS20360	COG2197	response regulator
ETL58_RS20365	COG2195	Cleaves the N-terminal amino acid of tripeptides
ETL58_RS20375	COG4894	glucomannan catabolic process
ETL58_RS20380	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ETL58_RS20385	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ETL58_RS20390	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_RS20395	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ETL58_RS20400	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ETL58_RS20405	COG2610	gluconate transmembrane transporter activity
ETL58_RS20410	COG0500	methyltransferase
ETL58_RS20415	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ETL58_RS20430	COG0693	protein deglycase activity
ETL58_RS20430	COG0753	catalase activity
ETL58_RS20435	COG2851	Citrate transporter
ETL58_RS20440	COG2273	Hydrolase Family 16
ETL58_RS20445	COG3711	transcriptional antiterminator
ETL58_RS20455	COG2270	Major facilitator Superfamily
ETL58_RS20460	COG0513	Belongs to the DEAD box helicase family
ETL58_RS20465	COG3401	FG-GAP repeat protein
ETL58_RS20465	COG2755	lipolytic protein G-D-S-L family
ETL58_RS20515	COG3209	COG3209 Rhs family protein
ETL58_RS20520	COG0697	spore germination
ETL58_RS20530	COG0789	Transcriptional regulator
ETL58_RS20550	COG0589	response to stress
ETL58_RS20555	COG2723	6-phospho-beta-galactosidase activity
ETL58_RS20560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETL58_RS20560	COG1263	PTS System
ETL58_RS20560	COG2190	(PTS) system
ETL58_RS20585	COG5444	nuclease activity
ETL58_RS20605	COG0494	nUDIX hydrolase
ETL58_RS20610	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
ETL58_RS20615	COG3507	Belongs to the glycosyl hydrolase 43 family
ETL58_RS20625	COG2986	histidine ammonia-lyase
ETL58_RS20630	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ETL58_RS20635	COG1228	amidohydrolase
ETL58_RS20640	COG0010	Belongs to the arginase family
ETL58_RS20645	COG0833	amino acid
ETL58_RS20650	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
ETL58_RS20655	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ETL58_RS20660	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ETL58_RS20665	COG2390	Transcriptional regulator
ETL58_RS20675	COG3192	ethanolamine utilization protein
ETL58_RS20680	COG2079	MmgE PrpD family protein
ETL58_RS20685	COG1473	amidohydrolase
ETL58_RS20690	COG1126	abc transporter atp-binding protein
ETL58_RS20695	COG0765	amino acid transport
ETL58_RS20700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETL58_RS20705	COG0456	acetyltransferase
ETL58_RS20710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ETL58_RS20720	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
ETL58_RS20725	COG0561	phosphatase activity
ETL58_RS20755	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ETL58_RS20760	COG5294	Protein conserved in bacteria
ETL58_RS20765	COG0577	efflux transmembrane transporter activity
ETL58_RS20770	COG1136	(ABC) transporter
ETL58_RS20775	COG2205	protein histidine kinase activity
ETL58_RS20780	COG0745	RESPONSE REGULATOR receiver
ETL58_RS20785	COG0191	fructose-bisphosphate aldolase activity
ETL58_RS20790	COG1082	Xylose isomerase domain protein TIM barrel
ETL58_RS20795	COG1082	Xylose isomerase domain protein TIM barrel
ETL58_RS20800	COG0673	inositol 2-dehydrogenase activity
ETL58_RS20805	COG2814	Major facilitator Superfamily
ETL58_RS20810	COG1082	Xylose isomerase domain protein TIM barrel
ETL58_RS20815	COG3962	Belongs to the TPP enzyme family
ETL58_RS20820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ETL58_RS20830	COG1012	belongs to the aldehyde dehydrogenase family
ETL58_RS20835	COG1349	DNA-binding transcription factor activity
ETL58_RS20840	COG0667	Aldo Keto reductase
ETL58_RS20855	COG2814	Major facilitator Superfamily
ETL58_RS20860	COG0326	Molecular chaperone. Has ATPase activity
ETL58_RS20870	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_RS20875	COG1309	transcriptional regulator
ETL58_RS20880	COG1012	belongs to the aldehyde dehydrogenase family
ETL58_RS20885	COG0456	acetyltransferase
ETL58_RS20890	COG2850	peptidyl-arginine hydroxylation
ETL58_RS20895	COG2226	methyltransferase
ETL58_RS20910	COG0367	asparagine synthase
ETL58_RS20915	COG2814	Major facilitator Superfamily
ETL58_RS20920	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ETL58_RS20930	COG1714	RDD family
ETL58_RS20935	COG2311	Membrane
ETL58_RS20940	COG1917	Cupin 2, conserved barrel domain protein
ETL58_RS20945	COG1309	transcriptional regulator
ETL58_RS20950	COG1028	Short-chain dehydrogenase reductase Sdr
ETL58_RS20955	COG1846	Transcriptional regulator
ETL58_RS20960	COG1380	Effector of murein hydrolase LrgA
ETL58_RS20965	COG1346	cytolysis
ETL58_RS20970	COG5039	Polysaccharide pyruvyl transferase
ETL58_RS20975	COG1929	Belongs to the glycerate kinase type-1 family
ETL58_RS20980	COG1802	Transcriptional regulator
ETL58_RS20985	COG1070	Carbohydrate kinase
ETL58_RS20990	COG2610	gluconate transmembrane transporter activity
ETL58_RS20995	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ETL58_RS21000	COG0450	alkyl hydroperoxide reductase
ETL58_RS21005	COG3634	alkyl hydroperoxide reductase activity
ETL58_RS21015	COG2723	6-phospho-beta-galactosidase activity
ETL58_RS21030	COG2188	Transcriptional regulator
ETL58_RS21040	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
ETL58_RS21075	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ETL58_RS21090	COG1063	alcohol dehydrogenase
ETL58_RS21110	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
ETL58_RS21115	COG0456	acetyltransferase
ETL58_RS21120	COG0457	Tetratricopeptide repeat
ETL58_RS21130	COG0010	Belongs to the arginase family
ETL58_RS21135	COG0833	amino acid
ETL58_RS21140	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ETL58_RS21145	COG3829	transcription factor binding
ETL58_RS21150	COG5002	protein histidine kinase activity
ETL58_RS21155	COG0745	RESPONSE REGULATOR receiver
ETL58_RS21175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETL58_RS21180	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ETL58_RS21185	COG4853	Protein conserved in bacteria
ETL58_RS21190	COG4863	YycH protein
ETL58_RS21195	COG5002	protein histidine kinase activity
ETL58_RS21200	COG0745	RESPONSE REGULATOR receiver
ETL58_RS21230	COG0346	lactoylglutathione lyase activity
ETL58_RS21235	COG0305	Participates in initiation and elongation during chromosome replication
ETL58_RS21250	COG3093	addiction module antidote protein HigA
ETL58_RS21255	COG2807	transmembrane transport
ETL58_RS21260	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ETL58_RS21265	COG0359	binds to the 23S rRNA
ETL58_RS21270	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
ETL58_RS21275	COG4241	membrane
ETL58_RS21285	COG5577	PFAM Coat F domain
ETL58_RS21290	COG1733	regulation of RNA biosynthetic process
ETL58_RS21295	COG1227	inorganic diphosphatase activity
ETL58_RS21305	COG2271	Major facilitator Superfamily
ETL58_RS21310	COG0789	Transcriptional regulator
ETL58_RS21310	COG4978	Transcriptional regulator
ETL58_RS21320	COG4319	ketosteroid isomerase
ETL58_RS21325	COG1357	PFAM Pentapeptide repeats (8 copies)
ETL58_RS21330	COG2814	Major facilitator Superfamily
ETL58_RS21335	COG0583	DNA-binding transcription factor activity
ETL58_RS21340	COG2153	protein acetylation
ETL58_RS21355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETL58_RS21360	COG1846	Transcriptional regulator
ETL58_RS21365	COG2153	protein acetylation
ETL58_RS21370	COG2364	Membrane
ETL58_RS21375	COG0456	acetyltransferase
ETL58_RS21380	COG2315	Protein conserved in bacteria
ETL58_RS21385	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ETL58_RS21395	COG2814	Major facilitator Superfamily
ETL58_RS21405	COG1331	Highly conserved protein containing a thioredoxin domain
ETL58_RS21410	COG1266	CAAX protease self-immunity
ETL58_RS21415	COG0477	Major facilitator Superfamily
ETL58_RS21415	COG2814	Major facilitator Superfamily
ETL58_RS21420	COG0110	maltose O-acetyltransferase activity
ETL58_RS21425	COG0346	lactoylglutathione lyase activity
ETL58_RS21430	COG1609	Transcriptional regulator
ETL58_RS21435	COG0708	Exodeoxyribonuclease III
ETL58_RS21440	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ETL58_RS21445	COG0629	single-stranded DNA binding
ETL58_RS21450	COG0360	Binds together with S18 to 16S ribosomal RNA
ETL58_RS21455	COG0012	GTP binding
ETL58_RS21460	COG0243	molybdopterin cofactor binding
ETL58_RS21465	COG4481	Protein conserved in bacteria
ETL58_RS21470	COG3949	Membrane
ETL58_RS21480	COG1475	DNA binding
ETL58_RS21485	COG1192	Involved in chromosome partitioning
ETL58_RS21495	COG1475	DNA binding
ETL58_RS21500	COG0357	Ribosomal RNA small subunit methyltransferase G
ETL58_RS21505	COG0445	tRNA wobble uridine modification
ETL58_RS21510	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ETL58_RS21515	COG1847	R3H domain protein
ETL58_RS21520	COG0706	membrane insertase activity
ETL58_RS21525	COG0594	ribonuclease P activity